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Search of human proteins with 21040349
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
(260 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 540 e-154
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 502 e-142
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 493 e-140
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 493 e-140
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 456 e-128
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 339 2e-93
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 311 3e-85
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 295 2e-80
gi|17986001 major histocompatibility complex, class I, B precurs... 177 1e-44
gi|149158702 major histocompatibility complex, class I, F isofor... 166 1e-41
gi|149158698 major histocompatibility complex, class I, F isofor... 166 1e-41
gi|52630342 major histocompatibility complex, class I, C precurs... 166 1e-41
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 166 1e-41
gi|24797067 major histocompatibility complex, class I, A precurs... 163 2e-40
gi|4504415 major histocompatibility complex, class I, G precurso... 159 2e-39
gi|4504417 major histocompatibility complex, class I-related [Ho... 157 7e-39
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 157 1e-38
gi|62912479 major histocompatibility complex, class I, E precurs... 155 3e-38
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 117 1e-26
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 113 2e-25
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 109 3e-24
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 109 3e-24
gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s... 99 4e-21
gi|239740918 PREDICTED: similar to major histocompatibility comp... 93 2e-19
gi|239740920 PREDICTED: similar to major histocompatibility comp... 93 3e-19
gi|169168591 PREDICTED: similar to major histocompatibility comp... 89 3e-18
gi|150418002 major histocompatibility complex, class II, DQ beta... 86 4e-17
gi|239740863 PREDICTED: similar to major histocompatibility comp... 85 6e-17
gi|239513955 PREDICTED: similar to major histocompatibility comp... 85 6e-17
gi|239758095 PREDICTED: similar to major histocompatibility comp... 85 7e-17
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 540 bits (1391), Expect = e-154
Identities = 260/260 (100%), Positives = 260/260 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
Query: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPP 120
CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPP
Sbjct: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPP 120
Query: 121 LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 180
LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI
Sbjct: 121 LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 180
Query: 181 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 240
TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII
Sbjct: 181 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 240
Query: 241 LRKRQGSRGAMGHYVLAERE 260
LRKRQGSRGAMGHYVLAERE
Sbjct: 241 LRKRQGSRGAMGHYVLAERE 260
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 502 bits (1293), Expect = e-142
Identities = 246/260 (94%), Positives = 246/260 (94%), Gaps = 14/260 (5%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
Query: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPP 120
CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV
Sbjct: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV-- 118
Query: 121 LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 180
TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI
Sbjct: 119 ------------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 166
Query: 181 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 240
TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII
Sbjct: 167 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 226
Query: 241 LRKRQGSRGAMGHYVLAERE 260
LRKRQGSRGAMGHYVLAERE
Sbjct: 227 LRKRQGSRGAMGHYVLAERE 246
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 493 bits (1270), Expect = e-140
Identities = 234/235 (99%), Positives = 235/235 (100%)
Query: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 91 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 150
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 145
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ
Sbjct: 151 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 210
Query: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 211 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 270
Query: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 260
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 271 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
Score = 50.1 bits (118), Expect = 2e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 493 bits (1270), Expect = e-140
Identities = 234/235 (99%), Positives = 235/235 (100%)
Query: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 114 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 173
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 145
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ
Sbjct: 174 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 233
Query: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 234 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 293
Query: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 260
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 294 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
Score = 59.3 bits (142), Expect = 3e-09
Identities = 31/52 (59%), Positives = 37/52 (71%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGY 52
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGY 52
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 456 bits (1172), Expect = e-128
Identities = 220/235 (93%), Positives = 221/235 (94%), Gaps = 14/235 (5%)
Query: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 114 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 173
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 145
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV TTLRCRALNYYPQ
Sbjct: 174 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV--------------TTLRCRALNYYPQ 219
Query: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 220 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 279
Query: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 260
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 280 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
Score = 59.3 bits (142), Expect = 3e-09
Identities = 31/52 (59%), Positives = 37/52 (71%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGY 52
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGY 52
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 339 bits (869), Expect = 2e-93
Identities = 182/261 (69%), Positives = 198/261 (75%), Gaps = 6/261 (2%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY F
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 CPDTLDWRAAEPRA-WPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVP 119
+ R EPR W + + ++ Q+ + ++E +VP
Sbjct: 61 YDH--ESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN---HSKVP 115
Query: 120 PLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGW 179
PLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGW
Sbjct: 116 PLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGW 175
Query: 180 ITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFI 239
ITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFI
Sbjct: 176 ITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFI 235
Query: 240 ILRKRQGSRGAMGHYVLAERE 260
ILRKRQGSRGAMGHYVLAERE
Sbjct: 236 ILRKRQGSRGAMGHYVLAERE 256
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 311 bits (798), Expect = 3e-85
Identities = 173/260 (66%), Positives = 189/260 (72%), Gaps = 18/260 (6%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY F
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPP 120
+ R EPR W +I ++ QL Q L+ +
Sbjct: 61 YDH--ESRRVEPRT-----PWVSSRISSQMW---------LQLSQSLKGWDHMFTVDFWT 104
Query: 121 LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 180
+++ +H S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI
Sbjct: 105 IMENHNH--SKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 162
Query: 181 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 240
TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII
Sbjct: 163 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 222
Query: 241 LRKRQGSRGAMGHYVLAERE 260
LRKRQGSRGAMGHYVLAERE
Sbjct: 223 LRKRQGSRGAMGHYVLAERE 242
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 295 bits (756), Expect = 2e-80
Identities = 142/143 (99%), Positives = 143/143 (100%)
Query: 118 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 177
+PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ
Sbjct: 26 LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 178 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 237
GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
Query: 238 FIILRKRQGSRGAMGHYVLAERE 260
FIILRKRQGSRGAMGHYVLAERE
Sbjct: 146 FIILRKRQGSRGAMGHYVLAERE 168
Score = 50.1 bits (118), Expect = 2e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 177 bits (448), Expect = 1e-44
Identities = 91/231 (39%), Positives = 138/231 (59%), Gaps = 5/231 (2%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GC++ D G+ +Y YDG+D++ D W AA+ A T+ +WE +
Sbjct: 116 SHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR 175
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
A Q RAYLE +C L++ LE G+ L++ PP VTHH ++ TLRC AL +YP
Sbjct: 176 -EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYP 234
Query: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
IT+ W +D + ++ E + P GD T+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKP 293
Query: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 254
L + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G G Y
Sbjct: 294 LTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 166 bits (421), Expect = 1e-41
Identities = 88/231 (38%), Positives = 134/231 (58%), Gaps = 5/231 (2%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GC+M D GY ++ YDG+D++ D W AA+ A T+ +E +
Sbjct: 113 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE 172
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
A + R YLE +C L++ LE G+ L + PP V HH ++ TLRC AL +YP
Sbjct: 173 Y-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYP 231
Query: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QP
Sbjct: 232 AEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQP 290
Query: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 254
LI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 291 LILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 166 bits (421), Expect = 1e-41
Identities = 88/231 (38%), Positives = 134/231 (58%), Gaps = 5/231 (2%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GC+M D GY ++ YDG+D++ D W AA+ A T+ +E +
Sbjct: 113 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE 172
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
A + R YLE +C L++ LE G+ L + PP V HH ++ TLRC AL +YP
Sbjct: 173 Y-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYP 231
Query: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QP
Sbjct: 232 AEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQP 290
Query: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 254
LI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 291 LILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 166 bits (421), Expect = 1e-41
Identities = 91/229 (39%), Positives = 132/229 (57%), Gaps = 5/229 (2%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GC++ D GY + YDG+D++ D W AA+ A T+ + E +
Sbjct: 116 SHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR 175
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSS-VTTLRCRALNYYP 144
A Q RAYLE C L++ LE G+ L + PP VTHH S TLRC AL +YP
Sbjct: 176 A-AEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYP 234
Query: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
IT+ W +D + ++ E + P GDGT+Q W + VP G+EQRYTC ++H GL +P
Sbjct: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEP 293
Query: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 252
L + WEPS T+ ++G+++G+AV VV+ +G + + R+ S G G
Sbjct: 294 LTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKG 342
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 166 bits (421), Expect = 1e-41
Identities = 91/228 (39%), Positives = 132/228 (57%), Gaps = 5/228 (2%)
Query: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ++ GC++ D G+ + YDG+D++ D W AA+ A TK + E
Sbjct: 129 SHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQITKRKREAAG 188
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
RQ R YLE C L++ LE G+ L + PP VTHH ++ TLRC AL +YP
Sbjct: 189 AAERQ-RNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRCWALGFYP 247
Query: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRYTC+V+H GL +P
Sbjct: 248 EEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGLQEP 306
Query: 205 LIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 252
L + WEP + L++G+I G+ + VV L G + I +KR G G G
Sbjct: 307 LTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 163 bits (412), Expect = 2e-40
Identities = 87/234 (37%), Positives = 133/234 (56%), Gaps = 5/234 (2%)
Query: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHT+Q++ GC++ D GY + YDG+D++ D W AA+ A TK +WE
Sbjct: 116 SHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH 175
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
A Q RAYL+ C L++ LE G+ L + PP +THH ++ TLRC AL +YP
Sbjct: 176 -EAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYP 234
Query: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 235 AEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKP 293
Query: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLA 257
L + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S G Y A
Sbjct: 294 LTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQA 347
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 159 bits (403), Expect = 2e-39
Identities = 86/224 (38%), Positives = 129/224 (57%), Gaps = 5/224 (2%)
Query: 27 SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ ++GC++ D GY +Y YDG+D+L D W AA+ A +K + E
Sbjct: 116 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN 175
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
+ A Q RAYLE C L + LE G+ +L + PP VTHH V TLRC AL +YP
Sbjct: 176 V-AEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYP 234
Query: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
I + W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 235 AEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP 293
Query: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 247
L++ W+ S T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 294 LMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 157 bits (398), Expect = 7e-39
Identities = 87/219 (39%), Positives = 127/219 (57%), Gaps = 4/219 (1%)
Query: 27 SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKI 86
SHT Q ++GCE+ ED ST G+ +Y YDGQD L F DTL W A + A K WE ++
Sbjct: 111 SHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQH 170
Query: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVT-SSVTTLRCRALNYYPQ 145
+ +LE +C A L++ LE G+ L + PPLV+V T VT L C+A +YP
Sbjct: 171 ELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPP 230
Query: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205
I M W+K+ + + +E + D+LP+GDGTYQ W ++ + P Y+C VEH G+ L
Sbjct: 231 EIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVL 289
Query: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 244
V E S + LV+ +SG V V++L G+ ++ R+R
Sbjct: 290 QVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 157 bits (396), Expect = 1e-38
Identities = 77/190 (40%), Positives = 113/190 (59%), Gaps = 9/190 (4%)
Query: 27 SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKI 86
SH LQ GCE++ + S+ +WKY YDG+D++EF + W +P A TK +WE +
Sbjct: 114 SHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPV 173
Query: 87 RARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRALNYYPQ 145
++ +AYLE +CPA L++ L+ + +LD+Q PP V VT H L+C A ++YP
Sbjct: 174 YVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPG 233
Query: 146 NITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD 202
I + W + + EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L
Sbjct: 234 KIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLA 288
Query: 203 QPLIVIWEPS 212
QPL+V WE S
Sbjct: 289 QPLVVPWEAS 298
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 155 bits (392), Expect = 3e-38
Identities = 85/235 (36%), Positives = 130/235 (55%), Gaps = 5/235 (2%)
Query: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
SHTLQ + GCE+ D GY ++ YDG+D+L D W A + A ++ +
Sbjct: 113 SHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDA 171
Query: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
A RAYLE C L + LE G+ L PP VTHH ++ TLRC AL +YP
Sbjct: 172 SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYP 231
Query: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 232 AEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP 290
Query: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 258
+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G G Y AE
Sbjct: 291 VTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAE 345
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 117 bits (293), Expect = 1e-26
Identities = 74/222 (33%), Positives = 112/222 (50%), Gaps = 22/222 (9%)
Query: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRA-----AEPRAWPTKLEWE 82
H+LQ I CE+ EDNST + YDG+ L +T +W A+ A + +
Sbjct: 111 HSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLK 170
Query: 83 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT-TLRCRALN 141
++ + + + DC +L++ L+ G VL + VPP+V VT S T+ CRA
Sbjct: 171 EDAMKTKTHYHAMHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASG 229
Query: 142 YYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL 201
+YP NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+TC +EH G
Sbjct: 230 FYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGN 289
Query: 202 DQPLIVIWEPSPSG----------TLVIGVISGIAVFVVILF 233
P PSG T + ++ A+FV+I+F
Sbjct: 290 HST-----HPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIF 326
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 113 bits (282), Expect = 2e-25
Identities = 68/198 (34%), Positives = 107/198 (54%), Gaps = 12/198 (6%)
Query: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQ----DHLEFCPDTLDWRA-AEPRAWPTKLEWE 82
H+LQ I CE+ ED+ST G + YDG+ +LE T+ + A+ A W+
Sbjct: 111 HSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWK 170
Query: 83 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRALN 141
++ + + ++ DC +LQ+ L+ G + + VPP+V VT V+ T+ CRA +
Sbjct: 171 EDAMKTKTHYRAMQADCLQKLQRYLKSGVAIR-RTVPPMVNVTCSEVSEGNITVTCRASS 229
Query: 142 YYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL 201
+YP+NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+TC +EH G
Sbjct: 230 FYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGN 289
Query: 202 DQPLIVIWEPSPSGTLVI 219
P PSG ++
Sbjct: 290 HGT-----HPVPSGKALV 302
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 109 bits (272), Expect = 3e-24
Identities = 64/212 (30%), Positives = 108/212 (50%), Gaps = 5/212 (2%)
Query: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIR 87
+TLQ +LGCE+ DN++ K+ +G++ + F W P A W++
Sbjct: 111 YTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKA 170
Query: 88 ARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALNYYPQN 146
A + +L CP +L++ LE GRG L+ + PP +++ +S + L C A ++YP
Sbjct: 171 ANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPE 230
Query: 147 ITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLI 206
+ +++L++ + D PN DG++ +L V G+E Y C V+H GL QPL
Sbjct: 231 LQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLR 287
Query: 207 VIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 237
V E P+ S LV+G++ G+ + G L
Sbjct: 288 VELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 109 bits (272), Expect = 3e-24
Identities = 64/212 (30%), Positives = 108/212 (50%), Gaps = 5/212 (2%)
Query: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIR 87
+TLQ +LGCE+ DN++ K+ +G++ + F W P A W++
Sbjct: 111 YTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKA 170
Query: 88 ARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALNYYPQN 146
A + +L CP +L++ LE GRG L+ + PP +++ +S + L C A ++YP
Sbjct: 171 ANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPE 230
Query: 147 ITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLI 206
+ +++L++ + D PN DG++ +L V G+E Y C V+H GL QPL
Sbjct: 231 LQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLR 287
Query: 207 VIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 237
V E P+ S LV+G++ G+ + G L
Sbjct: 288 VELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|21040357 hemochromatosis protein isoform 11 precursor [Homo
sapiens]
Length = 76
Score = 99.0 bits (245), Expect = 4e-21
Identities = 50/51 (98%), Positives = 51/51 (100%)
Query: 210 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 260
+PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 26 QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76
Score = 52.0 bits (123), Expect = 5e-07
Identities = 26/26 (100%), Positives = 26/26 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLQ 26
MGPRARPALLLLMLLQTAVLQGRLLQ
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQ 26
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 93.2 bits (230), Expect = 2e-19
Identities = 76/258 (29%), Positives = 117/258 (45%), Gaps = 13/258 (5%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTE---GYWKYGYDGQDHL 58
G R L+L +L T V +GR + G N TE G +Y Y+ +++
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGM-CYFTNGTERVRGVTRYIYNREEYA 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D +RA P P W K + RA L+ C Q LEL R L ++V
Sbjct: 71 RFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 PPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 175
P V ++ T ++ L C ++YP I ++W ++ Q + ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQE-ETTGVVSTPLIRNGDWT 186
Query: 176 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 234
+Q + L + P YTC VEHP L P+IV W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 235 GILFIILRKRQGSRGAMG 252
G+ II + Q G
Sbjct: 246 GLGLIIHHRSQKGEEPQG 263
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 92.8 bits (229), Expect = 3e-19
Identities = 75/251 (29%), Positives = 116/251 (46%), Gaps = 13/251 (5%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTE---GYWKYGYDGQDHL 58
G R L+L +L T V +GR + G N TE G +Y Y+ +++
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGM-CYFTNGTERVRGVTRYIYNREEYA 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D +RA P P W K + RA L+ C Q LEL R L ++V
Sbjct: 71 RFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 PPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 175
P V ++ T ++ L C ++YP I ++W ++ Q + ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQE-ETTGVVSTPLIRNGDWT 186
Query: 176 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 234
+Q + L + P YTC VEHP L P+IV W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 235 GILFIILRKRQ 245
G+ II + Q
Sbjct: 246 GLGLIIHHRSQ 256
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 89.4 bits (220), Expect = 3e-18
Identities = 74/251 (29%), Positives = 115/251 (45%), Gaps = 13/251 (5%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTE---GYWKYGYDGQDHL 58
G R L+L +L T V +GR + G N TE G +Y Y+ +++
Sbjct: 12 GLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGM-CYFTNGTERVRGVTRYIYNREEYA 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D +RA P P W K + RA ++ C Q LEL R L ++V
Sbjct: 71 RFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 PPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 175
P V ++ T ++ L C ++YP I ++W ++ Q A ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-LIRNGDWT 186
Query: 176 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 234
+Q + L + P YTC VEHP L P+ V W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 235 GILFIILRKRQ 245
G+ II + Q
Sbjct: 246 GLGLIIHHRSQ 256
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 85.5 bits (210), Expect = 4e-17
Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 9/201 (4%)
Query: 49 KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLE 108
+Y Y+ +++ F D +RA P+ P W K RA L+ C +
Sbjct: 61 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAF- 119
Query: 109 LGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEP 165
RG+L ++V P V ++ T ++ L C ++YP I ++W ++ Q A
Sbjct: 120 --RGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVST 177
Query: 166 KDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGI 225
++ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SG+
Sbjct: 178 P-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGV 235
Query: 226 AVFVV-ILFIGILFIILRKRQ 245
FV+ ++F+G+ II ++ Q
Sbjct: 236 GGFVLGLIFLGLGLIIRQRSQ 256
>gi|239740863 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 85.1 bits (209), Expect = 6e-17
Identities = 74/258 (28%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYG---YDGQDHL 58
G RA L+L +L T V +GR + G N TE Y+ ++ +
Sbjct: 12 GLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGM-CYFTNGTERVRLVSRSIYNREEIV 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D ++RA P W K + RA ++R C Q LEL R L ++V
Sbjct: 71 RFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 PPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 175
P V ++ T ++ L C ++YP I ++W ++ Q A ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-LIRNGDWT 186
Query: 176 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 234
+Q + L + P YTC VEHP L P+ V W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 235 GILFIILRKRQGSRGAMG 252
G+ II + Q G
Sbjct: 246 GLGLIIHHRSQKGEEPQG 263
>gi|239513955 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 85.1 bits (209), Expect = 6e-17
Identities = 74/258 (28%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYG---YDGQDHL 58
G RA L+L +L T V +GR + G N TE Y+ ++ +
Sbjct: 12 GLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGM-CYFTNGTERVRLVSRSIYNREEIV 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D ++RA P W K + RA ++R C Q LEL R L ++V
Sbjct: 71 RFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 PPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 175
P V ++ T ++ L C ++YP I ++W ++ Q A ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-LIRNGDWT 186
Query: 176 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 234
+Q + L + P YTC VEHP L P+ V W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 235 GILFIILRKRQGSRGAMG 252
G+ II + Q G
Sbjct: 246 GLGLIIHHRSQKGEEPQG 263
>gi|239758095 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 84.7 bits (208), Expect = 7e-17
Identities = 74/258 (28%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Query: 2 GPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYG---YDGQDHL 58
G RA L+L +L T V +GR + G N TE Y+ ++ +
Sbjct: 12 GLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGM-CYFTNGTERVRLVSRSIYNREEIV 70
Query: 59 EFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQV 118
F D ++RA P W K + RA ++R C Q LEL R L ++V
Sbjct: 71 RFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQ--LEL-RTTLQRRV 127
Query: 119 PPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 175
P V ++ T ++ L C ++YP I ++W ++ Q A ++ NGD T
Sbjct: 128 EPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTP-LIRNGDWT 186
Query: 176 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFI 234
+Q + L + P YTC VEHP L P+ V W + S + ++SGI FV+ ++F+
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGFVLGLIFL 245
Query: 235 GILFIILRKRQGSRGAMG 252
G+ II + Q G
Sbjct: 246 GLGLIIHHRSQKGEEPQG 263
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,267,205
Number of Sequences: 37866
Number of extensions: 543339
Number of successful extensions: 1513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1290
Number of HSP's gapped (non-prelim): 153
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.