Guide to the Human Genome
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Search of human proteins with 21040341

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
         (242 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa...   498   e-141
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa...   489   e-138
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa...   311   2e-85
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa...   311   4e-85
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s...   271   3e-73
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa...   271   3e-73
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap...   271   3e-73
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa...   269   2e-72
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi...   110   1e-24
gi|149158702 major histocompatibility complex, class I, F isofor...   108   3e-24
gi|149158698 major histocompatibility complex, class I, F isofor...   108   3e-24
gi|17986001 major histocompatibility complex, class I, B precurs...   108   4e-24
gi|52630342 major histocompatibility complex, class I, C precurs...   108   4e-24
gi|62912479 major histocompatibility complex, class I, E precurs...   100   9e-22
gi|24797067 major histocompatibility complex, class I, A precurs...   100   2e-21
gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s...    99   3e-21
gi|4504415 major histocompatibility complex, class I, G precurso...    94   1e-19
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi...    80   1e-15
gi|4504417 major histocompatibility complex, class I-related [Ho...    79   4e-15
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa...    75   5e-14
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]                 73   2e-13
gi|239740855 PREDICTED: similar to major histocompatibility comp...    68   6e-12
gi|239740853 PREDICTED: similar to major histocompatibility comp...    68   6e-12
gi|18641375 major histocompatibility complex, class II, DR beta ...    68   8e-12
gi|52630344 major histocompatibility complex, class II, DR beta ...    67   1e-11
gi|239758092 PREDICTED: similar to HLA class II histocompatibili...    67   1e-11
gi|239758090 PREDICTED: major histocompatibility complex, class ...    67   1e-11
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...    67   1e-11
gi|239740745 PREDICTED: similar to HLA class II histocompatibili...    67   1e-11
gi|239740743 PREDICTED: similar to HLA class II histocompatibili...    67   1e-11

>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
           sapiens]
          Length = 242

 Score =  498 bits (1283), Expect = e-141
 Identities = 242/242 (100%), Positives = 242/242 (100%)

Query: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
           MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60

Query: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCR 120
           YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCR
Sbjct: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCR 120

Query: 121 ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH 180
           ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH
Sbjct: 121 ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH 180

Query: 181 PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 240
           PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE
Sbjct: 181 PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 240

Query: 241 RE 242
           RE
Sbjct: 241 RE 242


>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
           sapiens]
          Length = 256

 Score =  489 bits (1258), Expect = e-138
 Identities = 242/256 (94%), Positives = 242/256 (94%), Gaps = 14/256 (5%)

Query: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
           MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60

Query: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKV------ 114
           YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKV      
Sbjct: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLVKV 120

Query: 115 --------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV 166
                   TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV
Sbjct: 121 THHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV 180

Query: 167 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 226
           PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR
Sbjct: 181 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 240

Query: 227 QGSRGAMGHYVLAERE 242
           QGSRGAMGHYVLAERE
Sbjct: 241 QGSRGAMGHYVLAERE 256


>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
           sapiens]
          Length = 260

 Score =  311 bits (798), Expect = 2e-85
 Identities = 173/260 (66%), Positives = 189/260 (72%), Gaps = 18/260 (6%)

Query: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
           MGPRARPALLLLMLLQTAVLQGRLL+SH+L  +     ++D     +   GY       F
Sbjct: 1   MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60

Query: 61  YDH--ESRRVEPRT-----PWVSSRISSQMW---------LQLSQSLKGWDHMFTVDFWT 104
                + R  EPR       W   +I ++            QL Q L+    +       
Sbjct: 61  CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPP 120

Query: 105 IMENHNH--SKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 162
           +++  +H  S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI
Sbjct: 121 LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 180

Query: 163 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 222
           TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII
Sbjct: 181 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 240

Query: 223 LRKRQGSRGAMGHYVLAERE 242
           LRKRQGSRGAMGHYVLAERE
Sbjct: 241 LRKRQGSRGAMGHYVLAERE 260


>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
           sapiens]
          Length = 246

 Score =  311 bits (796), Expect = 4e-85
 Identities = 168/247 (68%), Positives = 184/247 (74%), Gaps = 6/247 (2%)

Query: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
           MGPRARPALLLLMLLQTAVLQGRLL+SH+L  +     ++D     +   GY       F
Sbjct: 1   MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60

Query: 61  YDH--ESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN---HSKVT 115
                + R  EPR  W +     +  ++  Q+    +         ++E        +VT
Sbjct: 61  CPDTLDWRAAEPRA-WPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVT 119

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT
Sbjct: 120 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 179

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH 235
           CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH
Sbjct: 180 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH 239

Query: 236 YVLAERE 242
           YVLAERE
Sbjct: 240 YVLAERE 246


>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
           sapiens]
          Length = 168

 Score =  271 bits (694), Expect = 3e-73
 Identities = 131/135 (97%), Positives = 132/135 (97%)

Query: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167
           +H  S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP
Sbjct: 34  HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 93

Query: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227
           PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ
Sbjct: 94  PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 153

Query: 228 GSRGAMGHYVLAERE 242
           GSRGAMGHYVLAERE
Sbjct: 154 GSRGAMGHYVLAERE 168



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLL 25
          MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLL 25


>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
           sapiens]
          Length = 325

 Score =  271 bits (694), Expect = 3e-73
 Identities = 131/135 (97%), Positives = 132/135 (97%)

Query: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167
           +H  S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP
Sbjct: 191 HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 250

Query: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227
           PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ
Sbjct: 251 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 310

Query: 228 GSRGAMGHYVLAERE 242
           GSRGAMGHYVLAERE
Sbjct: 311 GSRGAMGHYVLAERE 325



 Score =  174 bits (440), Expect = 8e-44
 Identities = 89/113 (78%), Positives = 89/113 (78%), Gaps = 23/113 (20%)

Query: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
           MGPRARPALLLLMLLQTAVLQGRLL                        LGYVDDQLFVF
Sbjct: 1   MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37

Query: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
           YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 38  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 90


>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
           sapiens]
          Length = 348

 Score =  271 bits (694), Expect = 3e-73
 Identities = 131/135 (97%), Positives = 132/135 (97%)

Query: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167
           +H  S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP
Sbjct: 214 HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 273

Query: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227
           PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ
Sbjct: 274 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 333

Query: 228 GSRGAMGHYVLAERE 242
           GSRGAMGHYVLAERE
Sbjct: 334 GSRGAMGHYVLAERE 348



 Score =  234 bits (597), Expect = 5e-62
 Identities = 113/113 (100%), Positives = 113/113 (100%)

Query: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
           MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60

Query: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
           YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113


>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
           sapiens]
          Length = 334

 Score =  269 bits (687), Expect = 2e-72
 Identities = 129/130 (99%), Positives = 130/130 (100%)

Query: 113 KVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ 172
           +VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ
Sbjct: 205 QVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ 264

Query: 173 RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA 232
           RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA
Sbjct: 265 RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA 324

Query: 233 MGHYVLAERE 242
           MGHYVLAERE
Sbjct: 325 MGHYVLAERE 334



 Score =  234 bits (597), Expect = 5e-62
 Identities = 113/113 (100%), Positives = 113/113 (100%)

Query: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
           MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1   MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60

Query: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
           YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61  YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113


>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
           sapiens]
          Length = 366

 Score =  110 bits (274), Expect = 1e-24
 Identities = 52/119 (43%), Positives = 76/119 (63%), Gaps = 2/119 (1%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRC AL +YP+ I++ W ++ +    ++ E  +  P+GDGT+Q W  L VP GEEQRYT
Sbjct: 237 TLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYT 295

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
           C+V+H GL +PL + WEP  +  L++G+I G+ + VV L  G + I  +KR G  G  G
Sbjct: 296 CRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 27  SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84
           SHSL Y +   S   LG   F ++GYVDD  FV +D +S   R EPR PW+      + W
Sbjct: 39  SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97

Query: 85  LQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
            + ++ +K     F V   T+   +N S+
Sbjct: 98  DEQTRIVKDTAQSFRVGLNTLRGYYNQSE 126


>gi|149158702 major histocompatibility complex, class I, F isoform 1
           precursor [Homo sapiens]
          Length = 442

 Score =  108 bits (271), Expect = 3e-24
 Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q W  + VPPGEEQRYT
Sbjct: 221 TLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYT 279

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
           C V+H GL QPLI+ WE SP  T+ ++G+++G+ V   ++   ++  ++ +++ S    G
Sbjct: 280 CHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRG 339

Query: 235 HY 236
            Y
Sbjct: 340 SY 341



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 34/119 (28%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 7   PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
           P  LLL+L     L      SHSL Y     S    G   + A+ YVDD  F+ +D ++ 
Sbjct: 3   PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62

Query: 67  --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCRALN 123
             R+EPR PWV      Q W   +   K       V    ++  +N S+  +   + +N
Sbjct: 63  IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120


>gi|149158698 major histocompatibility complex, class I, F isoform 2
           precursor [Homo sapiens]
          Length = 346

 Score =  108 bits (271), Expect = 3e-24
 Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q W  + VPPGEEQRYT
Sbjct: 221 TLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYT 279

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
           C V+H GL QPLI+ WE SP  T+ ++G+++G+ V   ++   ++  ++ +++ S    G
Sbjct: 280 CHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRG 339

Query: 235 HY 236
            Y
Sbjct: 340 SY 341



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 34/119 (28%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 7   PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
           P  LLL+L     L      SHSL Y     S    G   + A+ YVDD  F+ +D ++ 
Sbjct: 3   PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62

Query: 67  --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCRALN 123
             R+EPR PWV      Q W   +   K       V    ++  +N S+  +   + +N
Sbjct: 63  IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120


>gi|17986001 major histocompatibility complex, class I, B precursor
           [Homo sapiens]
          Length = 362

 Score =  108 bits (270), Expect = 4e-24
 Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRC AL +YP  IT+ W +D +    ++ E  +  P GD T+Q W  + VP GEEQRYT
Sbjct: 224 TLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYT 282

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
           C V+H GL +PL + WEPS   T+ ++G+++G+AV  V++   ++  ++ +R+ S G  G
Sbjct: 283 CHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGG 342

Query: 235 HY 236
            Y
Sbjct: 343 SY 344



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 7  PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
          P  +LL+L     L      SHS+ Y +   S    G   F ++GYVDD  FV +D +  
Sbjct: 6  PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65

Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLK 92
          S R EPR PW+      + W + +Q  K
Sbjct: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYK 92


>gi|52630342 major histocompatibility complex, class I, C precursor
           [Homo sapiens]
          Length = 366

 Score =  108 bits (270), Expect = 4e-24
 Identities = 50/120 (41%), Positives = 76/120 (63%), Gaps = 2/120 (1%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q W  + VP G+EQRYT
Sbjct: 224 TLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYT 282

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
           C ++H GL +PL + WEPS   T+ ++G+++G+AV VV+  +G +   +  R+ S G  G
Sbjct: 283 CHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKG 342



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
          M PRA    LLL+L     L      SHS+ Y     S    G   F ++GYVDD  FV 
Sbjct: 4  MAPRA----LLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVR 59

Query: 61 YDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLK 92
          +D +  S R EPR PWV      + W + +Q  K
Sbjct: 60 FDSDAASPRGEPRAPWVEQE-GPEYWDRETQKYK 92


>gi|62912479 major histocompatibility complex, class I, E precursor
           [Homo sapiens]
          Length = 358

 Score =  100 bits (250), Expect = 9e-22
 Identities = 47/126 (37%), Positives = 78/126 (61%), Gaps = 2/126 (1%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q W  + VP GEEQRYT
Sbjct: 221 TLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYT 279

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
           C V+H GL +P+ + W+P+   T+ ++G+I+G+ +   ++   ++  ++ +++ S G  G
Sbjct: 280 CHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGG 339

Query: 235 HYVLAE 240
            Y  AE
Sbjct: 340 SYSKAE 345



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 3/106 (2%)

Query: 10  LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67
           LLL+L +   L      SHSL Y     S    G   F ++GYVDD  FV +D++  S R
Sbjct: 6   LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65

Query: 68  VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
           + PR PW+     S+ W + ++S +    +F V+  T+   +N S+
Sbjct: 66  MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSE 110


>gi|24797067 major histocompatibility complex, class I, A precursor
           [Homo sapiens]
          Length = 365

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 48/125 (38%), Positives = 75/125 (60%), Gaps = 2/125 (1%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRC AL +YP  IT+ W +D +    ++ E  +  P GDGT+Q W  + VP GEEQRYT
Sbjct: 224 TLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYT 282

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
           C V+H GL +PL + WE S   T+ ++G+I+G+ +   ++   ++  ++ +R+ S    G
Sbjct: 283 CHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGG 342

Query: 235 HYVLA 239
            Y  A
Sbjct: 343 SYTQA 347



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)

Query: 7   PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
           P  LLL+L     L      SHS+ Y F   S    G   F A+GYVDD  FV +D +  
Sbjct: 6   PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65

Query: 65  SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
           S+R+EPR PW+      + W Q ++++K       VD  T+   +N S+
Sbjct: 66  SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSE 113


>gi|21040357 hemochromatosis protein isoform 11 precursor [Homo
           sapiens]
          Length = 76

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 50/51 (98%), Positives = 51/51 (100%)

Query: 192 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 242
           +PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 26  QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/53 (54%), Positives = 37/53 (69%), Gaps = 3/53 (5%)

Query: 1  MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYV 53
          MGPRARPALLLLMLLQTAVLQGRLL+      L +G      G+++F  + ++
Sbjct: 1  MGPRARPALLLLMLLQTAVLQGRLLQPSPSGTLVIGVIS---GIAVFVVILFI 50


>gi|4504415 major histocompatibility complex, class I, G precursor
           [Homo sapiens]
          Length = 338

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 43/115 (37%), Positives = 71/115 (61%), Gaps = 2/115 (1%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           TLRC AL +YP  I + W +D +    ++ E  +  P GDGT+Q W  + VP GEEQRYT
Sbjct: 224 TLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYT 282

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 229
           C V+H GL +PL++ W+ S   T+ ++G+++G+ V   ++    +  +L +++ S
Sbjct: 283 CHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 3/112 (2%)

Query: 7   PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
           P  L L+L     L      SHS+ Y     S    G   F A+GYVDD  FV +D +S 
Sbjct: 6   PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65

Query: 67  --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTT 116
             R+EPR PWV      + W + +++ K       ++  T+   +N S+ ++
Sbjct: 66  CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASS 116


>gi|4557751 MHC class I polypeptide-related sequence A [Homo
           sapiens]
          Length = 383

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 41/110 (37%), Positives = 59/110 (53%), Gaps = 15/110 (13%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           T+ CRA  +YP NIT+ W +D   +     +  DVLP+G+GTYQ W+   +  GEEQR+T
Sbjct: 222 TVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFT 281

Query: 176 CQVEHPGLDQPLIVIWEPSPSG----------TLVIGVISGIAVFVVILF 215
           C +EH G          P PSG          T  +  ++  A+FV+I+F
Sbjct: 282 CYMEHSGNHST-----HPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIF 326



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 22/87 (25%), Positives = 35/87 (40%)

Query: 7  PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
          P  LLL  +      G     HSL Y     S      S F    ++D Q F+  D +  
Sbjct: 5  PVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC 64

Query: 67 RVEPRTPWVSSRISSQMWLQLSQSLKG 93
          R +P+  W    + ++ W + ++ L G
Sbjct: 65 RAKPQGQWAEDVLGNKTWDRETRDLTG 91


>gi|4504417 major histocompatibility complex, class I-related [Homo
           sapiens]
          Length = 341

 Score = 79.0 bits (193), Expect = 4e-15
 Identities = 43/113 (38%), Positives = 67/113 (59%), Gaps = 3/113 (2%)

Query: 114 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 173
           VT L C+A  +YP  I M W+K+ + +  +E +  D+LP+GDGTYQ W ++ + P     
Sbjct: 217 VTALFCKAHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNL 275

Query: 174 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 226
           Y+C VEH G+   L V  E S +  LV+  +SG  V V++L  G+  ++ R+R
Sbjct: 276 YSCHVEHCGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326



 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 35/102 (34%), Positives = 58/102 (56%)

Query: 11  LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEP 70
           LL L+   +++    R+HSL Y  +G S+   G+  F ++GYVD      YD  +R+ EP
Sbjct: 8   LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67

Query: 71  RTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
           R PW++  ++   W + +Q L+GW  MF V+   +  ++NHS
Sbjct: 68  RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS 109


>gi|167857788 MHC class I polypeptide-related sequence B [Homo
           sapiens]
          Length = 383

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 5/86 (5%)

Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
           T+ CRA ++YP+NIT+ W +D   +     +  DVLP+G+GTYQ W+   +  GEEQR+T
Sbjct: 222 TVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFT 281

Query: 176 CQVEHPGLDQPLIVIWEPSPSGTLVI 201
           C +EH G          P PSG  ++
Sbjct: 282 CYMEHSGNHGT-----HPVPSGKALV 302



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 20/57 (35%), Positives = 31/57 (54%)

Query: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMW 84
          HSL Y  M  S+     S F A G++D Q F+ YD + RR +P+  W  + + ++ W
Sbjct: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTW 82


>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
          Length = 298

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 35/81 (43%), Positives = 49/81 (60%), Gaps = 8/81 (9%)

Query: 117 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQR 173
           L+C A ++YP  I + W +  +       EP+   DVL NG+GTYQ W+ +AVPP +   
Sbjct: 223 LKCLAYDFYPGKIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAP 277

Query: 174 YTCQVEHPGLDQPLIVIWEPS 194
           Y+C V+H  L QPL+V WE S
Sbjct: 278 YSCHVQHSSLAQPLVVPWEAS 298



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 2/110 (1%)

Query: 4   RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62
           R  P LL LL+LL  AV Q      +SL Y++ G S+    +  F+ALG ++D  F  Y+
Sbjct: 3   RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62

Query: 63  HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112
            + R+ +P   W       + W Q SQ  K  + +F      I+E +N S
Sbjct: 63  SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDS 111


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 139 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 192

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 193 TVPRSGEVYTCQVEHPSVTSPLTVEWS-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 251

Query: 224 RKRQGSRG 231
           R ++G  G
Sbjct: 252 RNQKGHSG 259


>gi|239740853 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 138 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 191

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 192 TVPRSGEVYTCQVEHPSVTSPLTVEWS-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250

Query: 224 RKRQGSRG 231
           R ++G  G
Sbjct: 251 RNQKGHSG 258


>gi|18641375 major histocompatibility complex, class II, DR beta 5
           precursor [Homo sapiens]
          Length = 266

 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 138 LQHHN-----LLVCSVNGFYPGSIEVRWFRNSQEEKAGVVST-GLIQNGDWTFQTLVMLE 191

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 192 TVPRSGEVYTCQVEHPSVTSPLTVEWR-AQSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250

Query: 224 RKRQGSRG 231
           + ++G  G
Sbjct: 251 KNQKGHSG 258


>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 138 LQHHN-----LLVCSVNGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 191

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 192 TVPRSGEVYTCQVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFLGTGLFIYF 250

Query: 224 RKRQGSRG 231
           R ++G  G
Sbjct: 251 RNQKGHSG 258


>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 125 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 178

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 179 TVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 237

Query: 224 RKRQGSRG 231
           R ++G  G
Sbjct: 238 RNQKGHSG 245


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 150 LQHHN-----LLVCSVNGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 203

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 204 TVPRSGEVYTCQVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFLGTGLFIYF 262

Query: 224 RKRQGSRG 231
           R ++G  G
Sbjct: 263 RNQKGHSG 270


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 138 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 191

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 192 TVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250

Query: 224 RKRQGSRG 231
           R ++G  G
Sbjct: 251 RNQKGHSG 258


>gi|239740745 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 138 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 191

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 192 TVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250

Query: 224 RKRQGSRG 231
           R ++G  G
Sbjct: 251 RNQKGHSG 258


>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%)

Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165
           +++HN      L C    +YP +I ++W ++ Q   A       ++ NGD T+Q  + L 
Sbjct: 136 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 189

Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223
             P   + YTCQVEHP +  PL V W  + S +    ++SG+  FV+ +LF+G  LFI  
Sbjct: 190 TVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 248

Query: 224 RKRQGSRG 231
           R ++G  G
Sbjct: 249 RNQKGHSG 256


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,809,217
Number of Sequences: 37866
Number of extensions: 451372
Number of successful extensions: 1306
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1114
Number of HSP's gapped (non-prelim): 157
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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