BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sapiens] (242 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 498 e-141 gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 489 e-138 gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 311 2e-85 gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 311 4e-85 gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 271 3e-73 gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 271 3e-73 gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 271 3e-73 gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 269 2e-72 gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 110 1e-24 gi|149158702 major histocompatibility complex, class I, F isofor... 108 3e-24 gi|149158698 major histocompatibility complex, class I, F isofor... 108 3e-24 gi|17986001 major histocompatibility complex, class I, B precurs... 108 4e-24 gi|52630342 major histocompatibility complex, class I, C precurs... 108 4e-24 gi|62912479 major histocompatibility complex, class I, E precurs... 100 9e-22 gi|24797067 major histocompatibility complex, class I, A precurs... 100 2e-21 gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s... 99 3e-21 gi|4504415 major histocompatibility complex, class I, G precurso... 94 1e-19 gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 80 1e-15 gi|4504417 major histocompatibility complex, class I-related [Ho... 79 4e-15 gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 75 5e-14 gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 73 2e-13 gi|239740855 PREDICTED: similar to major histocompatibility comp... 68 6e-12 gi|239740853 PREDICTED: similar to major histocompatibility comp... 68 6e-12 gi|18641375 major histocompatibility complex, class II, DR beta ... 68 8e-12 gi|52630344 major histocompatibility complex, class II, DR beta ... 67 1e-11 gi|239758092 PREDICTED: similar to HLA class II histocompatibili... 67 1e-11 gi|239758090 PREDICTED: major histocompatibility complex, class ... 67 1e-11 gi|239748785 PREDICTED: similar to HLA class II histocompatibili... 67 1e-11 gi|239740745 PREDICTED: similar to HLA class II histocompatibili... 67 1e-11 gi|239740743 PREDICTED: similar to HLA class II histocompatibili... 67 1e-11 >gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sapiens] Length = 242 Score = 498 bits (1283), Expect = e-141 Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCR 120 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCR Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCR 120 Query: 121 ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH 180 ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH Sbjct: 121 ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH 180 Query: 181 PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 240 PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE Sbjct: 181 PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 240 Query: 241 RE 242 RE Sbjct: 241 RE 242 >gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sapiens] Length = 256 Score = 489 bits (1258), Expect = e-138 Identities = 242/256 (94%), Positives = 242/256 (94%), Gaps = 14/256 (5%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKV------ 114 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKV Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVPPLVKV 120 Query: 115 --------TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV 166 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV Sbjct: 121 THHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAV 180 Query: 167 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 226 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR Sbjct: 181 PPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 240 Query: 227 QGSRGAMGHYVLAERE 242 QGSRGAMGHYVLAERE Sbjct: 241 QGSRGAMGHYVLAERE 256 >gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sapiens] Length = 260 Score = 311 bits (798), Expect = 2e-85 Identities = 173/260 (66%), Positives = 189/260 (72%), Gaps = 18/260 (6%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY F Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60 Query: 61 YDH--ESRRVEPRT-----PWVSSRISSQMW---------LQLSQSLKGWDHMFTVDFWT 104 + R EPR W +I ++ QL Q L+ + Sbjct: 61 CPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPP 120 Query: 105 IMENHNH--SKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 162 +++ +H S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI Sbjct: 121 LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWI 180 Query: 163 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 222 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII Sbjct: 181 TLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFII 240 Query: 223 LRKRQGSRGAMGHYVLAERE 242 LRKRQGSRGAMGHYVLAERE Sbjct: 241 LRKRQGSRGAMGHYVLAERE 260 >gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sapiens] Length = 246 Score = 311 bits (796), Expect = 4e-85 Identities = 168/247 (68%), Positives = 184/247 (74%), Gaps = 6/247 (2%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY F Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEF 60 Query: 61 YDH--ESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN---HSKVT 115 + R EPR W + + ++ Q+ + ++E +VT Sbjct: 61 CPDTLDWRAAEPRA-WPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVT 119 Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT Sbjct: 120 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 179 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH 235 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH Sbjct: 180 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGH 239 Query: 236 YVLAERE 242 YVLAERE Sbjct: 240 YVLAERE 246 >gi|21040355 hemochromatosis protein isoform 10 precursor [Homo sapiens] Length = 168 Score = 271 bits (694), Expect = 3e-73 Identities = 131/135 (97%), Positives = 132/135 (97%) Query: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167 +H S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP Sbjct: 34 HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 93 Query: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ Sbjct: 94 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 153 Query: 228 GSRGAMGHYVLAERE 242 GSRGAMGHYVLAERE Sbjct: 154 GSRGAMGHYVLAERE 168 Score = 50.1 bits (118), Expect = 2e-06 Identities = 25/25 (100%), Positives = 25/25 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 MGPRARPALLLLMLLQTAVLQGRLL Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 >gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sapiens] Length = 325 Score = 271 bits (694), Expect = 3e-73 Identities = 131/135 (97%), Positives = 132/135 (97%) Query: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167 +H S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP Sbjct: 191 HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 250 Query: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ Sbjct: 251 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 310 Query: 228 GSRGAMGHYVLAERE 242 GSRGAMGHYVLAERE Sbjct: 311 GSRGAMGHYVLAERE 325 Score = 174 bits (440), Expect = 8e-44 Identities = 89/113 (78%), Positives = 89/113 (78%), Gaps = 23/113 (20%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37 Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK Sbjct: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 90 >gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sapiens] Length = 348 Score = 271 bits (694), Expect = 3e-73 Identities = 131/135 (97%), Positives = 132/135 (97%) Query: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167 +H S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP Sbjct: 214 HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 273 Query: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ Sbjct: 274 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 333 Query: 228 GSRGAMGHYVLAERE 242 GSRGAMGHYVLAERE Sbjct: 334 GSRGAMGHYVLAERE 348 Score = 234 bits (597), Expect = 5e-62 Identities = 113/113 (100%), Positives = 113/113 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 >gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sapiens] Length = 334 Score = 269 bits (687), Expect = 2e-72 Identities = 129/130 (99%), Positives = 130/130 (100%) Query: 113 KVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ 172 +VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ Sbjct: 205 QVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQ 264 Query: 173 RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA 232 RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA Sbjct: 265 RYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGA 324 Query: 233 MGHYVLAERE 242 MGHYVLAERE Sbjct: 325 MGHYVLAERE 334 Score = 234 bits (597), Expect = 5e-62 Identities = 113/113 (100%), Positives = 113/113 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 >gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapiens] Length = 366 Score = 110 bits (274), Expect = 1e-24 Identities = 52/119 (43%), Positives = 76/119 (63%), Gaps = 2/119 (1%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRC AL +YP+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRYT Sbjct: 237 TLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYT 295 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234 C+V+H GL +PL + WEP + L++G+I G+ + VV L G + I +KR G G G Sbjct: 296 CRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353 Score = 53.1 bits (126), Expect = 2e-07 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 3/89 (3%) Query: 27 SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84 SHSL Y + S LG F ++GYVDD FV +D +S R EPR PW+ + W Sbjct: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97 Query: 85 LQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 + ++ +K F V T+ +N S+ Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSE 126 >gi|149158702 major histocompatibility complex, class I, F isoform 1 precursor [Homo sapiens] Length = 442 Score = 108 bits (271), Expect = 3e-24 Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYT Sbjct: 221 TLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYT 279 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234 C V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G Sbjct: 280 CHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRG 339 Query: 235 HY 236 Y Sbjct: 340 SY 341 Score = 47.0 bits (110), Expect = 1e-05 Identities = 34/119 (28%), Positives = 50/119 (42%), Gaps = 3/119 (2%) Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66 P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++ Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62 Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCRALN 123 R+EPR PWV Q W + K V ++ +N S+ + + +N Sbjct: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120 >gi|149158698 major histocompatibility complex, class I, F isoform 2 precursor [Homo sapiens] Length = 346 Score = 108 bits (271), Expect = 3e-24 Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRYT Sbjct: 221 TLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYT 279 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234 C V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S G Sbjct: 280 CHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRG 339 Query: 235 HY 236 Y Sbjct: 340 SY 341 Score = 47.0 bits (110), Expect = 1e-05 Identities = 34/119 (28%), Positives = 50/119 (42%), Gaps = 3/119 (2%) Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66 P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++ Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62 Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTTLRCRALN 123 R+EPR PWV Q W + K V ++ +N S+ + + +N Sbjct: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120 >gi|17986001 major histocompatibility complex, class I, B precursor [Homo sapiens] Length = 362 Score = 108 bits (270), Expect = 4e-24 Identities = 50/122 (40%), Positives = 77/122 (63%), Gaps = 2/122 (1%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRC AL +YP IT+ W +D + ++ E + P GD T+Q W + VP GEEQRYT Sbjct: 224 TLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYT 282 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234 C V+H GL +PL + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G G Sbjct: 283 CHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGG 342 Query: 235 HY 236 Y Sbjct: 343 SY 344 Score = 49.7 bits (117), Expect = 2e-06 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 3/88 (3%) Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64 P +LL+L L SHS+ Y + S G F ++GYVDD FV +D + Sbjct: 6 PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65 Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLK 92 S R EPR PW+ + W + +Q K Sbjct: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYK 92 >gi|52630342 major histocompatibility complex, class I, C precursor [Homo sapiens] Length = 366 Score = 108 bits (270), Expect = 4e-24 Identities = 50/120 (41%), Positives = 76/120 (63%), Gaps = 2/120 (1%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP G+EQRYT Sbjct: 224 TLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYT 282 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234 C ++H GL +PL + WEPS T+ ++G+++G+AV VV+ +G + + R+ S G G Sbjct: 283 CHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKG 342 Score = 48.1 bits (113), Expect = 7e-06 Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 7/94 (7%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 M PRA LLL+L L SHS+ Y S G F ++GYVDD FV Sbjct: 4 MAPRA----LLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVR 59 Query: 61 YDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLK 92 +D + S R EPR PWV + W + +Q K Sbjct: 60 FDSDAASPRGEPRAPWVEQE-GPEYWDRETQKYK 92 >gi|62912479 major histocompatibility complex, class I, E precursor [Homo sapiens] Length = 358 Score = 100 bits (250), Expect = 9e-22 Identities = 47/126 (37%), Positives = 78/126 (61%), Gaps = 2/126 (1%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYT Sbjct: 221 TLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYT 279 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234 C V+H GL +P+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G G Sbjct: 280 CHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGG 339 Query: 235 HYVLAE 240 Y AE Sbjct: 340 SYSKAE 345 Score = 55.8 bits (133), Expect = 3e-08 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 3/106 (2%) Query: 10 LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67 LLL+L + L SHSL Y S G F ++GYVDD FV +D++ S R Sbjct: 6 LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65 Query: 68 VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 + PR PW+ S+ W + ++S + +F V+ T+ +N S+ Sbjct: 66 MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSE 110 >gi|24797067 major histocompatibility complex, class I, A precursor [Homo sapiens] Length = 365 Score = 99.8 bits (247), Expect = 2e-21 Identities = 48/125 (38%), Positives = 75/125 (60%), Gaps = 2/125 (1%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYT Sbjct: 224 TLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYT 282 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234 C V+H GL +PL + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S G Sbjct: 283 CHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGG 342 Query: 235 HYVLA 239 Y A Sbjct: 343 SYTQA 347 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%) Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64 P LLL+L L SHS+ Y F S G F A+GYVDD FV +D + Sbjct: 6 PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65 Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 S+R+EPR PW+ + W Q ++++K VD T+ +N S+ Sbjct: 66 SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSE 113 >gi|21040357 hemochromatosis protein isoform 11 precursor [Homo sapiens] Length = 76 Score = 99.0 bits (245), Expect = 3e-21 Identities = 50/51 (98%), Positives = 51/51 (100%) Query: 192 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 242 +PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE Sbjct: 26 QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/53 (54%), Positives = 37/53 (69%), Gaps = 3/53 (5%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYV 53 MGPRARPALLLLMLLQTAVLQGRLL+ L +G G+++F + ++ Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQPSPSGTLVIGVIS---GIAVFVVILFI 50 >gi|4504415 major histocompatibility complex, class I, G precursor [Homo sapiens] Length = 338 Score = 94.0 bits (232), Expect = 1e-19 Identities = 43/115 (37%), Positives = 71/115 (61%), Gaps = 2/115 (1%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 TLRC AL +YP I + W +D + ++ E + P GDGT+Q W + VP GEEQRYT Sbjct: 224 TLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYT 282 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 229 C V+H GL +PL++ W+ S T+ ++G+++G+ V ++ + +L +++ S Sbjct: 283 CHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337 Score = 53.9 bits (128), Expect = 1e-07 Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 3/112 (2%) Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66 P L L+L L SHS+ Y S G F A+GYVDD FV +D +S Sbjct: 6 PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65 Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKVTT 116 R+EPR PWV + W + +++ K ++ T+ +N S+ ++ Sbjct: 66 CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASS 116 >gi|4557751 MHC class I polypeptide-related sequence A [Homo sapiens] Length = 383 Score = 80.5 bits (197), Expect = 1e-15 Identities = 41/110 (37%), Positives = 59/110 (53%), Gaps = 15/110 (13%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 T+ CRA +YP NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+T Sbjct: 222 TVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFT 281 Query: 176 CQVEHPGLDQPLIVIWEPSPSG----------TLVIGVISGIAVFVVILF 215 C +EH G P PSG T + ++ A+FV+I+F Sbjct: 282 CYMEHSGNHST-----HPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIF 326 Score = 30.8 bits (68), Expect = 1.1 Identities = 22/87 (25%), Positives = 35/87 (40%) Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66 P LLL + G HSL Y S S F ++D Q F+ D + Sbjct: 5 PVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC 64 Query: 67 RVEPRTPWVSSRISSQMWLQLSQSLKG 93 R +P+ W + ++ W + ++ L G Sbjct: 65 RAKPQGQWAEDVLGNKTWDRETRDLTG 91 >gi|4504417 major histocompatibility complex, class I-related [Homo sapiens] Length = 341 Score = 79.0 bits (193), Expect = 4e-15 Identities = 43/113 (38%), Positives = 67/113 (59%), Gaps = 3/113 (2%) Query: 114 VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQR 173 VT L C+A +YP I M W+K+ + + +E + D+LP+GDGTYQ W ++ + P Sbjct: 217 VTALFCKAHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNL 275 Query: 174 YTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 226 Y+C VEH G+ L V E S + LV+ +SG V V++L G+ ++ R+R Sbjct: 276 YSCHVEHCGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326 Score = 75.1 bits (183), Expect = 5e-14 Identities = 35/102 (34%), Positives = 58/102 (56%) Query: 11 LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEP 70 LL L+ +++ R+HSL Y +G S+ G+ F ++GYVD YD +R+ EP Sbjct: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67 Query: 71 RTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112 R PW++ ++ W + +Q L+GW MF V+ + ++NHS Sbjct: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS 109 >gi|167857788 MHC class I polypeptide-related sequence B [Homo sapiens] Length = 383 Score = 75.1 bits (183), Expect = 5e-14 Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 5/86 (5%) Query: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175 T+ CRA ++YP+NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+T Sbjct: 222 TVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFT 281 Query: 176 CQVEHPGLDQPLIVIWEPSPSGTLVI 201 C +EH G P PSG ++ Sbjct: 282 CYMEHSGNHGT-----HPVPSGKALV 302 Score = 42.0 bits (97), Expect = 5e-04 Identities = 20/57 (35%), Positives = 31/57 (54%) Query: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMW 84 HSL Y M S+ S F A G++D Q F+ YD + RR +P+ W + + ++ W Sbjct: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTW 82 >gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] Length = 298 Score = 73.2 bits (178), Expect = 2e-13 Identities = 35/81 (43%), Positives = 49/81 (60%), Gaps = 8/81 (9%) Query: 117 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQR 173 L+C A ++YP I + W + + EP+ DVL NG+GTYQ W+ +AVPP + Sbjct: 223 LKCLAYDFYPGKIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAP 277 Query: 174 YTCQVEHPGLDQPLIVIWEPS 194 Y+C V+H L QPL+V WE S Sbjct: 278 YSCHVQHSSLAQPLVVPWEAS 298 Score = 46.6 bits (109), Expect = 2e-05 Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 2/110 (1%) Query: 4 RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62 R P LL LL+LL AV Q +SL Y++ G S+ + F+ALG ++D F Y+ Sbjct: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62 Query: 63 HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS 112 + R+ +P W + W Q SQ K + +F I+E +N S Sbjct: 63 SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDS 111 >gi|239740855 PREDICTED: similar to major histocompatibility complex, class II, DR beta 3 isoform 1 [Homo sapiens] Length = 267 Score = 68.2 bits (165), Expect = 6e-12 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 139 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 192 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 193 TVPRSGEVYTCQVEHPSVTSPLTVEWS-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 251 Query: 224 RKRQGSRG 231 R ++G G Sbjct: 252 RNQKGHSG 259 >gi|239740853 PREDICTED: similar to major histocompatibility complex, class II, DR beta 3 isoform 2 [Homo sapiens] Length = 266 Score = 68.2 bits (165), Expect = 6e-12 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 138 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 191 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 192 TVPRSGEVYTCQVEHPSVTSPLTVEWS-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250 Query: 224 RKRQGSRG 231 R ++G G Sbjct: 251 RNQKGHSG 258 >gi|18641375 major histocompatibility complex, class II, DR beta 5 precursor [Homo sapiens] Length = 266 Score = 67.8 bits (164), Expect = 8e-12 Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 138 LQHHN-----LLVCSVNGFYPGSIEVRWFRNSQEEKAGVVST-GLIQNGDWTFQTLVMLE 191 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 192 TVPRSGEVYTCQVEHPSVTSPLTVEWR-AQSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250 Query: 224 RKRQGSRG 231 + ++G G Sbjct: 251 KNQKGHSG 258 >gi|52630344 major histocompatibility complex, class II, DR beta 4 precursor [Homo sapiens] Length = 266 Score = 67.4 bits (163), Expect = 1e-11 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 138 LQHHN-----LLVCSVNGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 191 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 192 TVPRSGEVYTCQVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFLGTGLFIYF 250 Query: 224 RKRQGSRG 231 R ++G G Sbjct: 251 RNQKGHSG 258 >gi|239758092 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain [Homo sapiens] Length = 253 Score = 67.4 bits (163), Expect = 1e-11 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 125 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 178 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 179 TVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 237 Query: 224 RKRQGSRG 231 R ++G G Sbjct: 238 RNQKGHSG 245 >gi|239758090 PREDICTED: major histocompatibility complex, class II, DR beta 4 [Homo sapiens] Length = 278 Score = 67.4 bits (163), Expect = 1e-11 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 150 LQHHN-----LLVCSVNGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 203 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 204 TVPRSGEVYTCQVEHPSMMSPLTVQWS-ARSESAQSKMLSGVGGFVLGLLFLGTGLFIYF 262 Query: 224 RKRQGSRG 231 R ++G G Sbjct: 263 RNQKGHSG 270 >gi|239748785 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-9 beta chain [Homo sapiens] Length = 266 Score = 67.4 bits (163), Expect = 1e-11 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 138 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 191 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 192 TVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250 Query: 224 RKRQGSRG 231 R ++G G Sbjct: 251 RNQKGHSG 258 >gi|239740745 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain isoform 1 [Homo sapiens] Length = 266 Score = 67.4 bits (163), Expect = 1e-11 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 138 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 191 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 192 TVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 250 Query: 224 RKRQGSRG 231 R ++G G Sbjct: 251 RNQKGHSG 258 >gi|239740743 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain isoform 2 [Homo sapiens] Length = 264 Score = 67.4 bits (163), Expect = 1e-11 Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 9/128 (7%) Query: 106 MENHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLA 165 +++HN L C +YP +I ++W ++ Q A ++ NGD T+Q + L Sbjct: 136 LQHHN-----LLVCSVSGFYPGSIEVRWFRNGQEEKAGVVST-GLIQNGDWTFQTLVMLE 189 Query: 166 VPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVV-ILFIGI-LFIIL 223 P + YTCQVEHP + PL V W + S + ++SG+ FV+ +LF+G LFI Sbjct: 190 TVPRSGEVYTCQVEHPSVMSPLTVEWR-ARSESAQSKMLSGVGGFVLGLLFLGAGLFIYF 248 Query: 224 RKRQGSRG 231 R ++G G Sbjct: 249 RNQKGHSG 256 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.139 0.439 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,809,217 Number of Sequences: 37866 Number of extensions: 451372 Number of successful extensions: 1306 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 85 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 1114 Number of HSP's gapped (non-prelim): 157 length of query: 242 length of database: 18,247,518 effective HSP length: 99 effective length of query: 143 effective length of database: 14,498,784 effective search space: 2073326112 effective search space used: 2073326112 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.