Guide to the Human Genome
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Search of human proteins with 209915594

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209915594 transcription factor 3 isoform E47 [Homo sapiens]
         (651 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209915594 transcription factor 3 isoform E47 [Homo sapiens]       1311   0.0  
gi|27777636 transcription factor 3 isoform E12 [Homo sapiens]        1268   0.0  
gi|46370084 transcription factor 12 isoform b [Homo sapiens]          581   e-166
gi|4507391 transcription factor 12 isoform b [Homo sapiens]           581   e-166
gi|46370082 transcription factor 12 isoform a [Homo sapiens]          570   e-162
gi|46370080 transcription factor 12 isoform a [Homo sapiens]          570   e-162
gi|145312267 transcription factor 4 isoform a [Homo sapiens]          562   e-160
gi|4507399 transcription factor 4 isoform b [Homo sapiens]            560   e-159
gi|46370086 transcription factor 12 isoform c [Homo sapiens]          421   e-118
gi|57864582 hornerin [Homo sapiens]                                    61   3e-09
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      59   2e-08
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      59   2e-08
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    58   3e-08
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    58   3e-08
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       57   4e-08
gi|22027580 alpha 1 type XIII collagen isoform 6 [Homo sapiens]        57   7e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        56   1e-07
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            55   3e-07
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]             54   5e-07
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...    54   5e-07
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...    54   5e-07
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...    54   5e-07
gi|5031805 insulin receptor substrate 1 [Homo sapiens]                 54   6e-07
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...    54   6e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    53   1e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    53   1e-06
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    53   1e-06
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  52   1e-06
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 52   1e-06
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    51   3e-06

>gi|209915594 transcription factor 3 isoform E47 [Homo sapiens]
          Length = 651

 Score = 1311 bits (3392), Expect = 0.0
 Identities = 651/651 (100%), Positives = 651/651 (100%)

Query: 1   MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG 60
           MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG
Sbjct: 1   MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG 60

Query: 61  SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL 120
           SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL
Sbjct: 61  SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL 120

Query: 121 TQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL 180
           TQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL
Sbjct: 121 TQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL 180

Query: 181 PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPML 240
           PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPML
Sbjct: 181 PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPML 240

Query: 241 GGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGAT 300
           GGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGAT
Sbjct: 241 GGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGAT 300

Query: 301 YGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP 360
           YGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP
Sbjct: 301 YGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP 360

Query: 361 QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP 420
           QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP
Sbjct: 361 QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP 420

Query: 421 GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPD 480
           GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPD
Sbjct: 421 GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPD 480

Query: 481 SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSSTDEVLSLEEK 540
           SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSSTDEVLSLEEK
Sbjct: 481 SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSSTDEVLSLEEK 540

Query: 541 DLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLE 600
           DLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLE
Sbjct: 541 DLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLE 600

Query: 601 QQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651
           QQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM
Sbjct: 601 QQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651


>gi|27777636 transcription factor 3 isoform E12 [Homo sapiens]
          Length = 654

 Score = 1268 bits (3282), Expect = 0.0
 Identities = 630/654 (96%), Positives = 640/654 (97%), Gaps = 3/654 (0%)

Query: 1   MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG 60
           MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG
Sbjct: 1   MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG 60

Query: 61  SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL 120
           SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL
Sbjct: 61  SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL 120

Query: 121 TQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL 180
           TQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL
Sbjct: 121 TQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGL 180

Query: 181 PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPML 240
           PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPML
Sbjct: 181 PSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPML 240

Query: 241 GGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGAT 300
           GGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGAT
Sbjct: 241 GGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGAT 300

Query: 301 YGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP 360
           YGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP
Sbjct: 301 YGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP 360

Query: 361 QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP 420
           QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP
Sbjct: 361 QGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP 420

Query: 421 GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPD 480
           GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPD
Sbjct: 421 GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPD 480

Query: 481 SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTS---STDEVLSL 537
           SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTS     D++L  
Sbjct: 481 SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPP 540

Query: 538 EEKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVIL 597
           E+K  R++ERR+ANNARER+RVRDINEAF+ELGRMCQ+HL S+K QTKLLIL QAV VIL
Sbjct: 541 EQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVIL 600

Query: 598 GLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651
            LEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM
Sbjct: 601 NLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 654


>gi|46370084 transcription factor 12 isoform b [Homo sapiens]
          Length = 682

 Score =  581 bits (1498), Expect = e-166
 Identities = 347/698 (49%), Positives = 445/698 (63%), Gaps = 68/698 (9%)

Query: 3   QPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSG 62
           Q QRMA +GTDKELSDLLDFS MF  PV +GK RP +L  +QF GSG+++R  + SWG+ 
Sbjct: 4   QQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTS 63

Query: 63  DQSSSSFDPSRTFSEGTHFTE--------SHSSLSSSTFLGPGLGGKSGERGAYASFGRD 114
            Q S S+D SR F++  H+++        +H  LS + F+   L GK+ ERG+++ + RD
Sbjct: 64  GQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRD 123

Query: 115 AGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQP---K 171
            G+ G  Q+  L  +L L SP  LS SG  GT+ YY   + SSRRR    S    P   K
Sbjct: 124 TGLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTA-YYSFSATSSRRRPLHDSAALDPLQAK 181

Query: 172 KVRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP 230
           KVRKVPPGLPSSVY PS + +D+ R++ +YPS K P+S + + F++ DG+ H S++LWS 
Sbjct: 182 KVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT-HNSSDLWSS 240

Query: 231 PG---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGA---EVN 284
                Q GFG +LG  +S +              SS++G LH H+R+ Y  H     ++N
Sbjct: 241 SNGMSQPGFGGILGTSTSHM------------SQSSSYGNLHSHDRLSYPPHSVSPTDIN 288

Query: 285 GGLPSASSFSSAPGATYGGVS-SHTPPVSGADSLLGSRGTTAGSS--GDALGKALASIYS 341
             LP  SSF     ++   V+ SHTPP++G+DS+LG+RG  AGSS  GDALGKALASIYS
Sbjct: 289 TSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYS 348

Query: 342 PDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLD--- 398
           PDH+S++F S+PSTPVGSP  L GTSQWPR G     SPSY+  LH LQS++ED LD   
Sbjct: 349 PDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLD 408

Query: 399 EAIHVLRSHAVGTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGS 446
           +AIHVLR+HAVG +        D+H+LL P H    G+L S + G   +    +  + G+
Sbjct: 409 DAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGT 468

Query: 447 HPEDGLAGSTSLMHNHAALPSQPGTLP-DLS-RPPDSY-SGLGRAGATAAASEIKREEKE 503
           H ED    S SL  NH+ L S   T   DL+ +  ++Y  GL     T   +EIK E KE
Sbjct: 469 HRED----SVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKE 524

Query: 504 DEENTSAADHSEEEK-------KELK-APRARTSST--DEVLSLEEKDLRDRERRMANNA 553
            +EN      S++ K       K++K + R RTSST  DE L+ E+K  R++ERRMANNA
Sbjct: 525 KDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNA 584

Query: 554 RERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAA 613
           RER+RVRDINEAF+ELGRMCQ+HLKS+K QTKLLIL QAV VIL LEQQVRERNLNPKAA
Sbjct: 585 RERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAA 644

Query: 614 CLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651
           CLKRREEEKVS V  +P   L   HPGLSE  NP GHM
Sbjct: 645 CLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682


>gi|4507391 transcription factor 12 isoform b [Homo sapiens]
          Length = 682

 Score =  581 bits (1498), Expect = e-166
 Identities = 347/698 (49%), Positives = 445/698 (63%), Gaps = 68/698 (9%)

Query: 3   QPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSG 62
           Q QRMA +GTDKELSDLLDFS MF  PV +GK RP +L  +QF GSG+++R  + SWG+ 
Sbjct: 4   QQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTS 63

Query: 63  DQSSSSFDPSRTFSEGTHFTE--------SHSSLSSSTFLGPGLGGKSGERGAYASFGRD 114
            Q S S+D SR F++  H+++        +H  LS + F+   L GK+ ERG+++ + RD
Sbjct: 64  GQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRD 123

Query: 115 AGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQP---K 171
            G+ G  Q+  L  +L L SP  LS SG  GT+ YY   + SSRRR    S    P   K
Sbjct: 124 TGLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTA-YYSFSATSSRRRPLHDSAALDPLQAK 181

Query: 172 KVRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP 230
           KVRKVPPGLPSSVY PS + +D+ R++ +YPS K P+S + + F++ DG+ H S++LWS 
Sbjct: 182 KVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT-HNSSDLWSS 240

Query: 231 PG---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGA---EVN 284
                Q GFG +LG  +S +              SS++G LH H+R+ Y  H     ++N
Sbjct: 241 SNGMSQPGFGGILGTSTSHM------------SQSSSYGNLHSHDRLSYPPHSVSPTDIN 288

Query: 285 GGLPSASSFSSAPGATYGGVS-SHTPPVSGADSLLGSRGTTAGSS--GDALGKALASIYS 341
             LP  SSF     ++   V+ SHTPP++G+DS+LG+RG  AGSS  GDALGKALASIYS
Sbjct: 289 TSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYS 348

Query: 342 PDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLD--- 398
           PDH+S++F S+PSTPVGSP  L GTSQWPR G     SPSY+  LH LQS++ED LD   
Sbjct: 349 PDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLD 408

Query: 399 EAIHVLRSHAVGTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGS 446
           +AIHVLR+HAVG +        D+H+LL P H    G+L S + G   +    +  + G+
Sbjct: 409 DAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGT 468

Query: 447 HPEDGLAGSTSLMHNHAALPSQPGTLP-DLS-RPPDSY-SGLGRAGATAAASEIKREEKE 503
           H ED    S SL  NH+ L S   T   DL+ +  ++Y  GL     T   +EIK E KE
Sbjct: 469 HRED----SVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKE 524

Query: 504 DEENTSAADHSEEEK-------KELK-APRARTSST--DEVLSLEEKDLRDRERRMANNA 553
            +EN      S++ K       K++K + R RTSST  DE L+ E+K  R++ERRMANNA
Sbjct: 525 KDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNA 584

Query: 554 RERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAA 613
           RER+RVRDINEAF+ELGRMCQ+HLKS+K QTKLLIL QAV VIL LEQQVRERNLNPKAA
Sbjct: 585 RERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAA 644

Query: 614 CLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651
           CLKRREEEKVS V  +P   L   HPGLSE  NP GHM
Sbjct: 645 CLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682


>gi|46370082 transcription factor 12 isoform a [Homo sapiens]
          Length = 706

 Score =  570 bits (1469), Expect = e-162
 Identities = 345/722 (47%), Positives = 445/722 (61%), Gaps = 92/722 (12%)

Query: 3   QPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSG 62
           Q QRMA +GTDKELSDLLDFS MF  PV +GK RP +L  +QF GSG+++R  + SWG+ 
Sbjct: 4   QQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTS 63

Query: 63  DQSSSSFDPSRTFSEGTHFTE--------SHSSLSSSTFLGPGLGGKSGERGAYASFGRD 114
            Q S S+D SR F++  H+++        +H  LS + F+   L GK+ ERG+++ + RD
Sbjct: 64  GQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRD 123

Query: 115 AGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQP---K 171
            G+ G  Q+  L  +L L SP  LS SG  GT+ YY   + SSRRR    S    P   K
Sbjct: 124 TGLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTA-YYSFSATSSRRRPLHDSAALDPLQAK 181

Query: 172 KVRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP 230
           KVRKVPPGLPSSVY PS + +D+ R++ +YPS K P+S + + F++ DG+ H S++LWS 
Sbjct: 182 KVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT-HNSSDLWSS 240

Query: 231 PG---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGA---EVN 284
                Q GFG +LG  +S +              SS++G LH H+R+ Y  H     ++N
Sbjct: 241 SNGMSQPGFGGILGTSTSHM------------SQSSSYGNLHSHDRLSYPPHSVSPTDIN 288

Query: 285 GGLPSASSFSSAPGATYGGVS-SHTPPVSGADSLLGSRGTTAGSS--GDALGKALASIYS 341
             LP  SSF     ++   V+ SHTPP++G+DS+LG+RG  AGSS  GDALGKALASIYS
Sbjct: 289 TSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYS 348

Query: 342 PDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIE------- 394
           PDH+S++F S+PSTPVGSP  L GTSQWPR G     SPSY+  LH L++++E       
Sbjct: 349 PDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLKNRVEQQLHEHL 408

Query: 395 --------------------DHLDEAIHVLRSHAVGTA-------GDMHTLL-PGH---- 422
                               D LD+AIHVLR+HAVG +        D+H+LL P H    
Sbjct: 409 QDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPI 468

Query: 423 GALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLP-DLS-RPPD 480
           G+L S + G   +    +  + G+H ED    S SL  NH+ L S   T   DL+ +  +
Sbjct: 469 GSLNSNYGGSSLVASSRSASMVGTHRED----SVSLNGNHSVLSSTVTTSSTDLNHKTQE 524

Query: 481 SY-SGLGRAGATAAASEIKREEKEDEENTSAADHSEEEK-------KELK-APRARTSST 531
           +Y  GL     T   +EIK E KE +EN      S++ K       K++K + R RTSST
Sbjct: 525 NYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSST 584

Query: 532 --DEVLSLEEKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLIL 589
             DE L+ E+K  R++ERRMANNARER+RVRDINEAF+ELGRMCQ+HLKS+K QTKLLIL
Sbjct: 585 NEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLIL 644

Query: 590 QQAVQVILGLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAG 649
            QAV VIL LEQQVRERNLNPKAACLKRREEEKVS V  +P   L   HPGLSE  NP G
Sbjct: 645 HQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMG 704

Query: 650 HM 651
           HM
Sbjct: 705 HM 706


>gi|46370080 transcription factor 12 isoform a [Homo sapiens]
          Length = 706

 Score =  570 bits (1469), Expect = e-162
 Identities = 345/722 (47%), Positives = 445/722 (61%), Gaps = 92/722 (12%)

Query: 3   QPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSG 62
           Q QRMA +GTDKELSDLLDFS MF  PV +GK RP +L  +QF GSG+++R  + SWG+ 
Sbjct: 4   QQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTS 63

Query: 63  DQSSSSFDPSRTFSEGTHFTE--------SHSSLSSSTFLGPGLGGKSGERGAYASFGRD 114
            Q S S+D SR F++  H+++        +H  LS + F+   L GK+ ERG+++ + RD
Sbjct: 64  GQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRD 123

Query: 115 AGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQP---K 171
            G+ G  Q+  L  +L L SP  LS SG  GT+ YY   + SSRRR    S    P   K
Sbjct: 124 TGLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTA-YYSFSATSSRRRPLHDSAALDPLQAK 181

Query: 172 KVRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP 230
           KVRKVPPGLPSSVY PS + +D+ R++ +YPS K P+S + + F++ DG+ H S++LWS 
Sbjct: 182 KVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT-HNSSDLWSS 240

Query: 231 PG---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGA---EVN 284
                Q GFG +LG  +S +              SS++G LH H+R+ Y  H     ++N
Sbjct: 241 SNGMSQPGFGGILGTSTSHM------------SQSSSYGNLHSHDRLSYPPHSVSPTDIN 288

Query: 285 GGLPSASSFSSAPGATYGGVS-SHTPPVSGADSLLGSRGTTAGSS--GDALGKALASIYS 341
             LP  SSF     ++   V+ SHTPP++G+DS+LG+RG  AGSS  GDALGKALASIYS
Sbjct: 289 TSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYS 348

Query: 342 PDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIE------- 394
           PDH+S++F S+PSTPVGSP  L GTSQWPR G     SPSY+  LH L++++E       
Sbjct: 349 PDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLKNRVEQQLHEHL 408

Query: 395 --------------------DHLDEAIHVLRSHAVGTA-------GDMHTLL-PGH---- 422
                               D LD+AIHVLR+HAVG +        D+H+LL P H    
Sbjct: 409 QDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPI 468

Query: 423 GALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLP-DLS-RPPD 480
           G+L S + G   +    +  + G+H ED    S SL  NH+ L S   T   DL+ +  +
Sbjct: 469 GSLNSNYGGSSLVASSRSASMVGTHRED----SVSLNGNHSVLSSTVTTSSTDLNHKTQE 524

Query: 481 SY-SGLGRAGATAAASEIKREEKEDEENTSAADHSEEEK-------KELK-APRARTSST 531
           +Y  GL     T   +EIK E KE +EN      S++ K       K++K + R RTSST
Sbjct: 525 NYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSST 584

Query: 532 --DEVLSLEEKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLIL 589
             DE L+ E+K  R++ERRMANNARER+RVRDINEAF+ELGRMCQ+HLKS+K QTKLLIL
Sbjct: 585 NEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLIL 644

Query: 590 QQAVQVILGLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAG 649
            QAV VIL LEQQVRERNLNPKAACLKRREEEKVS V  +P   L   HPGLSE  NP G
Sbjct: 645 HQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMG 704

Query: 650 HM 651
           HM
Sbjct: 705 HM 706


>gi|145312267 transcription factor 4 isoform a [Homo sapiens]
          Length = 671

 Score =  562 bits (1449), Expect = e-160
 Identities = 351/698 (50%), Positives = 456/698 (65%), Gaps = 74/698 (10%)

Query: 1   MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG 60
           M+  QRMA +GTDKELSDLLDFS MF  PV++GK  P SLA   F GS +EDR SSGSWG
Sbjct: 1   MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG 60

Query: 61  SGDQSSSSFDPSRTFSEGT---HFTE----SHSSLSSSTFLGPGLGGKSGERGAYASFGR 113
           +G   S    PSR + +GT   H T     SH +LS   F+   +  K+ ERG+Y+S+GR
Sbjct: 61  NGGHPS----PSRNYGDGTPYDHMTSRDLGSHDNLSPP-FVNSRIQSKT-ERGSYSSYGR 114

Query: 114 DAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGS-LDTQPKK 172
           ++ + G  Q   L G++ + +PG LSP+  K  SQYY   S + RRR    S ++ Q KK
Sbjct: 115 ESNLQGCHQQSLLGGDMDMGNPGTLSPT--KPGSQYYQYSSNNPRRRPLHSSAMEVQTKK 172

Query: 173 VRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPP 231
           VRKVPPGLPSSVY PS S  DY RD+  YPS+K  +ST+P+ F++ DG  H S++ WS  
Sbjct: 173 VRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG--HHSSDPWSSS 230

Query: 232 G---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHG-AEVNGGL 287
               Q G+  MLG  SS +P             SS++  LH HER+ Y  H  A++N  L
Sbjct: 231 SGMNQPGYAGMLGN-SSHIP------------QSSSYCSLHPHERLSYPSHSSADINSSL 277

Query: 288 PSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT-TAGSS--GDALGKALASIYSPDH 344
           P  S+F  + G  +   SS TPP +G DS++ +RG+  AGSS  GDALGKALASIYSPDH
Sbjct: 278 PPMSTFHRS-GTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDH 336

Query: 345 SSNNFSSSPSTPVGSPQGL-AGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHL---DEA 400
           ++N+FSS+PSTPVGSP  L AGT+ W R G   + SP+Y+G LH LQS+IED L   D+A
Sbjct: 337 TNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDA 396

Query: 401 IHVLRSHAVGTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGSHP 448
           IHVLR+HAVG +       GDMH ++ P H    G L SG+   +    RH+ +VG +H 
Sbjct: 397 IHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVG-THR 455

Query: 449 EDGLA--GSTSLMHNHAALPSQP---GTLPDLSRPPDSYSGL--GRAG--ATAAASEIKR 499
           EDG+A  GS SL+ N   +P  P    T PDL+ P D Y G+  G  G   ++ +SEIK 
Sbjct: 456 EDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKS 515

Query: 500 EEKEDE--ENTSAADHS--EEEKKELKA-PRARTSSTD-EVLSLEEKDLRDRERRMANNA 553
           +++ DE  ++T +++    +++KK++K+  R+R+S+ D E L+ E+K  R++ERRMANNA
Sbjct: 516 DDEGDENLQDTKSSEDKKLDDDKKDIKSITRSRSSNNDDEDLTPEQKAEREKERRMANNA 575

Query: 554 RERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAA 613
           RER+RVRDINEAF+ELGRM Q+HLKSDK QTKLLIL QAV VIL LEQQVRERNLNPKAA
Sbjct: 576 RERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAA 635

Query: 614 CLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651
           CLKRREEEKVS     P + L+ PHPG+ +A N  G M
Sbjct: 636 CLKRREEEKVSS--EPPPLSLAGPHPGMGDASNHMGQM 671


>gi|4507399 transcription factor 4 isoform b [Homo sapiens]
          Length = 667

 Score =  560 bits (1444), Expect = e-159
 Identities = 348/696 (50%), Positives = 453/696 (65%), Gaps = 74/696 (10%)

Query: 1   MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWG 60
           M+  QRMA +GTDKELSDLLDFS MF  PV++GK  P SLA   F GS +EDR SSGSWG
Sbjct: 1   MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWG 60

Query: 61  SGDQSSSSFDPSRTFSEGT---HFTE----SHSSLSSSTFLGPGLGGKSGERGAYASFGR 113
           +G   S    PSR + +GT   H T     SH +LS   F+   +  K+ ERG+Y+S+GR
Sbjct: 61  NGGHPS----PSRNYGDGTPYDHMTSRDLGSHDNLSPP-FVNSRIQSKT-ERGSYSSYGR 114

Query: 114 DAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGS-LDTQPKK 172
           ++ + G  Q   L G++ + +PG LSP+  K  SQYY   S + RRR    S ++ Q KK
Sbjct: 115 ESNLQGCHQQSLLGGDMDMGNPGTLSPT--KPGSQYYQYSSNNPRRRPLHSSAMEVQTKK 172

Query: 173 VRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPP 231
           VRKVPPGLPSSVY PS S  DY RD+  YPS+K  +ST+P+ F++ DG  H S++ WS  
Sbjct: 173 VRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG--HHSSDPWSSS 230

Query: 232 G---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHG-AEVNGGL 287
               Q G+  MLG  SS +P             SS++  LH HER+ Y  H  A++N  L
Sbjct: 231 SGMNQPGYAGMLGN-SSHIP------------QSSSYCSLHPHERLSYPSHSSADINSSL 277

Query: 288 PSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT-TAGSS--GDALGKALASIYSPDH 344
           P  S+F  + G  +   SS TPP +G DS++ +RG+  AGSS  GDALGKALASIYSPDH
Sbjct: 278 PPMSTFHRS-GTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDH 336

Query: 345 SSNNFSSSPSTPVGSPQGL-AGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHL---DEA 400
           ++N+FSS+PSTPVGSP  L AGT+ W R G   + SP+Y+G LH LQS+IED L   D+A
Sbjct: 337 TNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDA 396

Query: 401 IHVLRSHAVGTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGSHP 448
           IHVLR+HAVG +       GDMH ++ P H    G L SG+   +    RH+ +VG +H 
Sbjct: 397 IHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVG-THR 455

Query: 449 EDGLA--GSTSLMHNHAALPSQP---GTLPDLSRPPDSYSGL--GRAG--ATAAASEIKR 499
           EDG+A  GS SL+ N   +P  P    T PDL+ P D Y G+  G  G   ++ +SEIK 
Sbjct: 456 EDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKS 515

Query: 500 EEKEDE--ENTSAADHS--EEEKKELKAPRARTSSTDEVLSLEEKDLRDRERRMANNARE 555
           +++ DE  ++T +++    +++KK++K+    +++ DE L+ E+K  R++ERRMANNARE
Sbjct: 516 DDEGDENLQDTKSSEDKKLDDDKKDIKS--ITSNNDDEDLTPEQKAEREKERRMANNARE 573

Query: 556 RVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAACL 615
           R+RVRDINEAF+ELGRM Q+HLKSDK QTKLLIL QAV VIL LEQQVRERNLNPKAACL
Sbjct: 574 RLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACL 633

Query: 616 KRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651
           KRREEEKVS     P + L+ PHPG+ +A N  G M
Sbjct: 634 KRREEEKVSS--EPPPLSLAGPHPGMGDASNHMGQM 667


>gi|46370086 transcription factor 12 isoform c [Homo sapiens]
          Length = 512

 Score =  421 bits (1083), Expect = e-118
 Identities = 255/507 (50%), Positives = 326/507 (64%), Gaps = 55/507 (10%)

Query: 183 SVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPG---QAGFGP 238
           +VY PS + +D+ R++ +YPS K P+S + + F++ DG+ H S++LWS      Q GFG 
Sbjct: 23  TVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT-HNSSDLWSSSNGMSQPGFGG 81

Query: 239 MLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGA---EVNGGLPSASSFSS 295
           +LG  +S +              SS++G LH H+R+ Y  H     ++N  LP  SSF  
Sbjct: 82  ILGTSTSHM------------SQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHR 129

Query: 296 APGATYGGVS-SHTPPVSGADSLLGSRGTTAGSS--GDALGKALASIYSPDHSSNNFSSS 352
              ++   V+ SHTPP++G+DS+LG+RG  AGSS  GDALGKALASIYSPDH+S++F S+
Sbjct: 130 GSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSN 189

Query: 353 PSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLD---EAIHVLRSHAV 409
           PSTPVGSP  L GTSQWPR G     SPSY+  LH LQS++ED LD   +AIHVLR+HAV
Sbjct: 190 PSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAV 249

Query: 410 GTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTS 457
           G +        D+H+LL P H    G+L S + G   +    +  + G+H ED    S S
Sbjct: 250 GPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHRED----SVS 305

Query: 458 LMHNHAALPSQPGTLP-DLS-RPPDSY-SGLGRAGATAAASEIKREEKEDEENTSAADHS 514
           L  NH+ L S   T   DL+ +  ++Y  GL     T   +EIK E KE +EN      S
Sbjct: 306 LNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSS 365

Query: 515 EEEK-------KELK-APRARTSST--DEVLSLEEKDLRDRERRMANNARERVRVRDINE 564
           ++ K       K++K + R RTSST  DE L+ E+K  R++ERRMANNARER+RVRDINE
Sbjct: 366 DDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINE 425

Query: 565 AFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAACLKRREEEKVS 624
           AF+ELGRMCQ+HLKS+K QTKLLIL QAV VIL LEQQVRERNLNPKAACLKRREEEKVS
Sbjct: 426 AFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVS 485

Query: 625 GVVGDPQMVLSAPHPGLSEAHNPAGHM 651
            V  +P   L   HPGLSE  NP GHM
Sbjct: 486 AVSAEPPTTLPGTHPGLSETTNPMGHM 512


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 114/439 (25%), Positives = 154/439 (35%), Gaps = 55/439 (12%)

Query: 32   NGKGRPASLAGAQFG-GSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS 90
            +G G   SL   Q G GSG    PS G  GSG   SSS+ P R+   G+ ++ S     S
Sbjct: 986  HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS---GSGWSSSRGPYES 1042

Query: 91   STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYY 150
             +    GLG +    G  + +G+     G +      G    ++ G  S  G  G S   
Sbjct: 1043 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG----STSGQSSSCGQHGAS--- 1095

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTY 210
               SG S      GS  +Q     +   G         SG+  G       S ++PS   
Sbjct: 1096 ---SGQSSSHGQHGSGSSQSSGYGRQGSG---------SGQSPGHGQRGSGSRQSPSYGR 1143

Query: 211  PAPFYVADGSLHPSAELWSPPGQ-AGFG-PMLGGGSSPLPLPPGSGPVGSSGSSSTFGGL 268
                    G    S +  S  G+ +GFG      G S      GSG    SG SS +G  
Sbjct: 1144 HGS---GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG----SGHSSGYG-- 1194

Query: 269  HQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSS 328
             QH     Q    E +G    +SS     G+     S H    SG+         + G  
Sbjct: 1195 -QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS-----GHSPSRGRH 1248

Query: 329  GDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDG---- 384
            G  LG    S     H S +  SS   P  S  G +       +G+  + + S  G    
Sbjct: 1249 GSGLGH---SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 1305

Query: 385  -----GLHGLQSKIEDHLD-EAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGR 438
                 G HG  S      D E     +S + G  G   +   G+G   +G +G     GR
Sbjct: 1306 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAG-SGQSPSRGR 1364

Query: 439  HAGLVGGSHPEDGLAGSTS 457
            H G   G     G  GS S
Sbjct: 1365 H-GSGSGHSSSYGQHGSGS 1382



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 117/510 (22%), Positives = 174/510 (34%), Gaps = 70/510 (13%)

Query: 47   GSGLEDRPSSGSWGSGDQSSSSF-----DPSRTFSEGTHFTES-HSSLSSSTFLGPGLGG 100
            GS      S G  GSG   SSS+        ++ S G H + S HSS       G G   
Sbjct: 1797 GSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1856

Query: 101  KSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRR 160
             SG  G  +  G+ +G G    + + S     +  G    SG   + + + S SG S R 
Sbjct: 1857 SSGRHG--SGSGQSSGFGHHESSSWQSSGYTQHGSG----SGHSSSYEQHGSRSGQSSRG 1910

Query: 161  AADGSLDTQPKKVRKVPPGLPSSV----YPPSSGEDYGRDATAYPSAKTPSSTYPAPFYV 216
               GS         +   G   S+    +   SG+        + S    SS+Y  P+  
Sbjct: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY-GPYGS 1969

Query: 217  ADGSLHPSAELWSP---PGQAGFGPM--LGGGSSPLPLPPGSGPVG-SSGSSSTFG---- 266
              G        WS    P ++G G    LG   S      G G  G SSG SST G    
Sbjct: 1970 GSG--------WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2021

Query: 267  --------GLHQHERMGYQLHGAEVNGGLPSA------SSFSSAPGATYGGVSSHTPPVS 312
                    G H         HG   +G   S+      S    +PG    G  S   P  
Sbjct: 2022 ASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 2081

Query: 313  GADSLLGSRGTTAGSSGDALGKA-------LASIYSPDHSSNNFSSSPSTPVGSPQGLAG 365
            G       R +++G  G  LG++        +S  S  +S +   S  S+  G     +G
Sbjct: 2082 GRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG 2141

Query: 366  -TSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGA 424
             +S+  R G+    S  Y  G HG  S+              H    +G  H+   G   
Sbjct: 2142 QSSRGERHGSSSGSSSRY--GQHGSGSRQSS----------GHGRQGSGSGHSPSRGRHG 2189

Query: 425  LASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSG 484
              SG +      G  +G      P +  +G +S+   H +                 +  
Sbjct: 2190 SGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 2249

Query: 485  LGRAGATAA-ASEIKREEKEDEENTSAADH 513
             G+ G+T+  +S   +E     +++S   H
Sbjct: 2250 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQH 2279



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 113/439 (25%), Positives = 154/439 (35%), Gaps = 55/439 (12%)

Query: 32   NGKGRPASLAGAQFG-GSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS 90
            +G G   SL   Q G GSG    PS G  GSG   SSS+ P   +  G+ ++ S     S
Sbjct: 2396 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSP---YGSGSGWSSSRGPYES 2452

Query: 91   STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYY 150
             +    GLG +    G  + +G+     G +      G    ++ G  S  G  G S   
Sbjct: 2453 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG----STSGQSSSCGQHGAS--- 2505

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTY 210
               SG S      GS  +Q     +   G         SG+  G       S ++PS   
Sbjct: 2506 ---SGQSSSHGQHGSGSSQSSGYGRQGSG---------SGQSPGHGQRGSGSRQSPSYGR 2553

Query: 211  PAPFYVADGSLHPSAELWSPPGQ-AGFG-PMLGGGSSPLPLPPGSGPVGSSGSSSTFGGL 268
                    G    S +  S  G+ +GFG      G S      GSG    SG SS +G  
Sbjct: 2554 HGS---GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG----SGHSSGYG-- 2604

Query: 269  HQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSS 328
             QH     Q    E +G    +SS     G+     S H    SG+      +  + G  
Sbjct: 2605 -QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS-----GQSPSRGRH 2658

Query: 329  GDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDG---- 384
            G  LG    S     H S +  SS   P  S  G +       +G+  + + S  G    
Sbjct: 2659 GSGLGH---SSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSG 2715

Query: 385  -----GLHGLQSKIEDHLD-EAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGR 438
                 G HG  S      D E     +S + G  G   +   G+G   +G +G     GR
Sbjct: 2716 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAG-SGQSLSHGR 2774

Query: 439  HAGLVGGSHPEDGLAGSTS 457
            H G   G     G  GS S
Sbjct: 2775 H-GSGSGQSSSYGQHGSGS 2792



 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 127/511 (24%), Positives = 172/511 (33%), Gaps = 53/511 (10%)

Query: 32   NGKGRPASLAGAQFG-GSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS 90
            +G G   SL   Q G GSG    PS G  GSG   SSS+ P   +  G+ ++ S     S
Sbjct: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP---YGSGSGWSSSRGPYES 1982

Query: 91   STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYY 150
             +    GLG +    G  + +G+     G +      G    ++ G  S  G  G S   
Sbjct: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG----SASGQSSSCGQHGAS--- 2035

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTY 210
               SG S      GS  +Q     +   G         SG+  G       S ++PS   
Sbjct: 2036 ---SGQSSSHGQHGSGSSQSSGYGRQGSG---------SGQSPGHGQRGSGSRQSPSYGR 2083

Query: 211  PAPFYVADGSLHPSAELWSPPG---QAGFG-PMLGGGSSPLPLPPGSGPVGSSG---SSS 263
                    GS   S+     PG    +GFG      G S      GSG   SSG     S
Sbjct: 2084 H-----GSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 2138

Query: 264  TFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTP------PVSGADSL 317
              G   + ER G     +   G   S S  SS  G   G  S H+P        SG  S 
Sbjct: 2139 RSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG-RQGSGSGHSPSRGRHGSGSGHSSS 2197

Query: 318  LGSRGTTAG---SSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGA 374
             G  G+ +G   S G    ++  S     H S +  SS  +  GS  G    SQ      
Sbjct: 2198 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG-HFCSQGQHGST 2256

Query: 375  PGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMS 434
             G  S     G    QS    H        +S + G  G      P  G   SG +G  S
Sbjct: 2257 SGQSSTFDQEGSSTGQS--SSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG-SGHSS 2313

Query: 435  LGGRHAGLVGGSHPE----DGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGA 490
              G+H    G S        G   S+   H+ ++     G     S    S S       
Sbjct: 2314 SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSR 2373

Query: 491  TAAASEIKREEKEDEENTSAADHSEEEKKEL 521
            +  +S  +R       ++S   H    ++ L
Sbjct: 2374 SGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 2404



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 106/402 (26%), Positives = 140/402 (34%), Gaps = 53/402 (13%)

Query: 32   NGKGRPASLAGAQFG-GSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS 90
            +G G   SL   Q G GSG    PS G  GSG   SSS+ P   +  G+ ++ S     S
Sbjct: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSP---YGSGSGWSSSRGPYES 1512

Query: 91   STFLGPGLG---GKSGERGAYASFGRDAGVGGL-TQAGFLSGELAL-----NSPGPLSPS 141
             +    GLG    +SG+   Y   G  +G      Q G  SG+ +       S G  S  
Sbjct: 1513 GSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1572

Query: 142  GMKGTSQYYP-------SYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYG 194
            G  G+            S SG S      GS   Q     +   G   S      G   G
Sbjct: 1573 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1632

Query: 195  RDA--TAYPSAKTPSSTYPAPFYVADGSLHPS--AELWSPPGQAGFGPMLGGGS------ 244
              +    + S+   SS+Y        GS H S   +  S  GQ+  G   G  S      
Sbjct: 1633 ESSGFGHHESSSGQSSSYSQH---GSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY 1689

Query: 245  ----SPLPLPPGSGPVGSSGSSSTFGGLH--------QHERMGYQLHGAEVNGGLPSASS 292
                S      G G  GS    S   G H         H + G     +   G   S S 
Sbjct: 1690 GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSG 1749

Query: 293  FSSA-----PGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSN 347
             SS       G+ +    S     SG     G  G+T+G S     +  ++  S  H  +
Sbjct: 1750 HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQH 1809

Query: 348  NFSSSPSTPVGSPQGLAGTSQWPRAGAPGALS-PSYDGGLHG 388
               SS S+  G  QG +G+ Q P  G  G+ S  S   G HG
Sbjct: 1810 GSGSSQSSSYGQ-QG-SGSGQSPSRGRHGSGSGHSSSYGQHG 1849



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 122/521 (23%), Positives = 172/521 (33%), Gaps = 64/521 (12%)

Query: 41   AGAQFGGSGLEDRPS--SGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGL 98
            A   F   G     S  S S G  D SS            +H         S +   PG 
Sbjct: 834  ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGH 893

Query: 99   GGKSGERGAYASFGR-DAGVGGLTQAG-FLSGELALNSPGPLSPSGMKGTSQYYPSYSGS 156
            G +    G   S+GR  +G G  + +G   SG    +  G  S SG       + S SG 
Sbjct: 894  GQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGH 953

Query: 157  SRRRAADGSLDTQPKKVRK--VPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPF 214
            S      GS   Q  +  +     G  SS     SG    R +  +    + S   P+P 
Sbjct: 954  SSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSG---SRQSLGHGQHGSGSGQSPSPS 1010

Query: 215  YVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERM 274
                GS    +  + P     +    G  SS  P   GSG     G   +  G    +  
Sbjct: 1011 RGRHGSGSGQSSSYGP-----YRSGSGWSSSRGPYESGSGHSSGLGHRESRSG----QSS 1061

Query: 275  GYQLHGAE--------VNGGLPSASSFSSAPGATYGGVSSHTPPVSGA--DSLLGSRGTT 324
            GY  HG+          +G     SS     GA+ G  SSH    SG+   S  G +G+ 
Sbjct: 1062 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1121

Query: 325  AGSSGDALGKALASIYSPD---HSSNNFSSSPSTPVGSPQGLAG-----------TSQWP 370
            +G S     +   S  SP    H S +  SS S   GS  G +            +S + 
Sbjct: 1122 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1181

Query: 371  RAGAPGALSPSY--DGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASG 428
            + G+    S  Y   G   G  S+ E H   +     S   G  G       GHG   SG
Sbjct: 1182 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS---GSSSHYGQHGSGSRQSSGHGRQGSG 1238

Query: 429  FTGPMSLGGRHAGLVG-----GSH-----------PEDGLAGSTSLMHNHAALPSQPGTL 472
             +G     GRH   +G     G H           P +  +G +S+   H +        
Sbjct: 1239 -SGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAY 1297

Query: 473  PDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADH 513
                     +   G+ G+T+  S    +E      +S+  H
Sbjct: 1298 SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGH 1338



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 121/502 (24%), Positives = 170/502 (33%), Gaps = 80/502 (15%)

Query: 47   GSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERG 106
            G+G    PS G  GSG   SSS+        G H + S  S SSS   G G G  SG   
Sbjct: 1353 GAGSGQSPSRGRHGSGSGHSSSY--------GQHGSGSGWS-SSSGRHGSGSGQSSGFGH 1403

Query: 107  AYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSL 166
              +S  + +   G TQ G  SG  +       S SG     + + S SGSS      GS 
Sbjct: 1404 HESSSWQSS---GCTQHGSGSGHSSSYEQHG-SRSGQSSRGERHGSSSGSSSSYGQHGSG 1459

Query: 167  DTQ----------------PKKVRKVPPGLPSSVYPP-SSGEDYGRDATAYPSAKTPSST 209
              Q                P + R       SS Y P  SG  +      Y S  + SS 
Sbjct: 1460 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSS- 1518

Query: 210  YPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLH 269
                     G  H  +      G    G   G  S+        G  GS+   S+  G H
Sbjct: 1519 ---------GLGHRESRSGQSSGYGQHGSSSGHSST-------HGQHGSTSGQSSSCGQH 1562

Query: 270  QHERMGYQLHGAEVNGGLPSA------SSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT 323
                     HG   +G   S+      S    +PG    G  S   P  G       R +
Sbjct: 1563 GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS 1622

Query: 324  TAGSSGDALGKA-------LASIYSPDHSSNNFSSSPSTPVGSPQGLAG-TSQWPRAGAP 375
            ++G  G  LG++        +S  S  +S +   S  S+  G     +G +S+  R G+ 
Sbjct: 1623 SSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSS 1682

Query: 376  GALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSL 435
               S  Y  G HG  S+            +S   G  G      P  G   SG  G  S 
Sbjct: 1683 SRSSSRY--GQHGSGSR------------QSSGHGRQGSGSGQSPSRGRHGSGL-GHSSS 1727

Query: 436  GGRHAGLVGGSH---PEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATA 492
             G+H    G S    P +  +G +S+   H +                 +   G+ G+T+
Sbjct: 1728 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1787

Query: 493  A-ASEIKREEKEDEENTSAADH 513
              +S   +E     +++S   H
Sbjct: 1788 GQSSTFDQEGSSTGQSSSHGQH 1809



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 122/476 (25%), Positives = 162/476 (34%), Gaps = 65/476 (13%)

Query: 47  GSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERG 106
           GSG    P+ G  GSG   SSS D   T   G+  +   S   SS          SG+  
Sbjct: 196 GSGSGQSPNYGQHGSGSGQSSSND---THGSGSGQSSGFSQHKSS----------SGQSS 242

Query: 107 AYASFGRDAG-VGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRR----RA 161
            Y+  G  +G   G  Q G  SG+   +S G    S    +S Y    SGS +     R 
Sbjct: 243 GYSQHGSGSGHSSGYGQHGSRSGQ---SSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQ 299

Query: 162 ADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSL 221
             GS  +          G  SS     SG  Y      Y S    +S +        GS 
Sbjct: 300 GSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQH---ESGSG 356

Query: 222 HPSAELWSPPGQ-AGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLH----------- 269
             S   +S  G  +G     G   S       SG  GSS   S+  G H           
Sbjct: 357 QSSG--YSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414

Query: 270 QHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSG 329
           QH     Q  G    G     S  S   G  +G  SS  P VSG+       G ++G   
Sbjct: 415 QHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGS-------GYSSGFGH 467

Query: 330 DALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGL 389
                  +S Y+  H S +  SS     GS  G   +S+  R G+    S SY  G HG 
Sbjct: 468 HESSSEHSSGYT-QHGSGSGHSSGHGQHGSRSG--QSSRGERQGSSAGSSSSY--GQHGS 522

Query: 390 QSKIEDHLDEAIHVLRS----------HAVGTAGDMHTLLPGHGALASGFTGPMSLGGRH 439
            S+    L  + H   S          H  G+         G+G+  S   GP   G  H
Sbjct: 523 GSR--QSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGH 580

Query: 440 AGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAAS 495
           +  +G    ++  +G +S    H +      T           S  G+ GAT+  S
Sbjct: 581 SSGLG---HQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQS 633



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 130/505 (25%), Positives = 170/505 (33%), Gaps = 84/505 (16%)

Query: 47   GSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLG------- 99
            GSG    P  G  GSG + S S+        G H + S  S SS    GPGLG       
Sbjct: 2059 GSGSGQSPGHGQRGSGSRQSPSY--------GRHGSGSGRSSSSGQH-GPGLGESSGFGH 2109

Query: 100  --GKSGERGAYASFGRDAG-VGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGS 156
                SG+  +Y+  G  +G   G  Q G  SG+   +S G    S    +S+Y    SGS
Sbjct: 2110 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ---SSRGERHGSSSGSSSRYGQHGSGS 2166

Query: 157  SRR----RAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPA 212
             +     R   GS  +  +       G  SS     SG         Y S    SS +  
Sbjct: 2167 RQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ 2226

Query: 213  PFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFG----GL 268
                  GS H SA      G   F      GS+            S+G SS+ G    G 
Sbjct: 2227 H---ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS 2283

Query: 269  HQHERMGYQLHGAEVNGGLPSASSFSSAPG--ATYGGVSSHTPPVSGADSLLGSRGTTAG 326
             Q    G Q  G+   G  PS     S  G  ++YG   S     SG  S  G  G+ +G
Sbjct: 2284 SQSSSYGQQGSGS---GQSPSRGRHGSGSGHSSSYGQHGSG----SGWSSSSGRHGSGSG 2336

Query: 327  SS---GDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYD 383
             S   G     +  S     H S +  SS     GS  G +  S+  R G+    S SY 
Sbjct: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS--SRGERHGSSSGSSSSY- 2393

Query: 384  GGLHGLQSKIEDHLDEAIHVLRS----------HAVGTAGDMHTLLPGHGALASGFTGPM 433
             G HG  S+    L    H   S          H  G+         G G+  S   GP 
Sbjct: 2394 -GQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPY 2450

Query: 434  SLGGRHAGLVG----------------------GSHPEDG-LAGSTSLMHNHAALPSQPG 470
              G  H+  +G                       +H + G  +G +S    H A   Q  
Sbjct: 2451 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 2510

Query: 471  TLPDLSRPPDSYSGLGRAGATAAAS 495
            +           SG GR G+ +  S
Sbjct: 2511 SHGQHGSGSSQSSGYGRQGSGSGQS 2535



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 139/590 (23%), Positives = 202/590 (34%), Gaps = 108/590 (18%)

Query: 31   TNGKGRPASLAGAQFG--GSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSL 88
            ++G+    S   +++G  GSG    PS G  GS    SSS+    + S  +     H S+
Sbjct: 635  SHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSV 694

Query: 89   SSSTFLGPGLGGKSGERGAYASFGRDAG-VGGLTQAGFLSGELAL-----NSPGPLSPSG 142
            S  +  G G    SG+   Y+  G  +    G  + G  SG+ +      +S G  S  G
Sbjct: 695  SGQS-SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYG 753

Query: 143  MKGTSQYYP-------SYSGSSRRRAADGSLDTQPKKVRKVPPGLPSS------------ 183
              G+  +         S SG S  R   GS         +   G   S            
Sbjct: 754  QHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQ 813

Query: 184  -----VYPPSSGEDYGRDATA----------------------YPSAKTPSSTY----PA 212
                  +   SG+ Y +  +A                      + S+   SS+Y     A
Sbjct: 814  ASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESA 873

Query: 213  PFYVADGSLHPSAELWSP-PGQAGFG----PMLGGGSSPLPLPPGSGPVGS-SGSSSTFG 266
              + +    H S    SP  GQ G G    P  G   S       SG  GS SG SS FG
Sbjct: 874  SHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFG 933

Query: 267  GLHQH-ERMGYQLHGA--------EVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSL 317
                  +  GY  HG+        E +G     SS S   G++ G  SS+    SG+   
Sbjct: 934  HKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQS 993

Query: 318  L--GSRGTTAGSSGD------ALGKALASIYSPDHSSNNFSSS---------PSTPVGSP 360
            L  G  G+ +G S          G   +S Y P  S + +SSS          S+ +G  
Sbjct: 994  LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHR 1053

Query: 361  QGLAGTSQW-----------PRAGAPGALS-PSYDGGLHGLQS-KIEDHLDEAIHVLRSH 407
            +  +G S                G  G+ S  S   G HG  S +   H        +S 
Sbjct: 1054 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 1113

Query: 408  AVGTAGDMHTLLPGHGALASGFTGPMSLG--GRHAGLVGGSHPEDGLAGSTSLMHNHAAL 465
              G  G      PGHG   SG     S G  G  +G    S       G +S   +H + 
Sbjct: 1114 GYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESS 1173

Query: 466  PSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSE 515
              Q  +           SG G+ G+ +  S   R E+    + S++ + +
Sbjct: 1174 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQS--SRGERHGSSSGSSSHYGQ 1221



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 114/451 (25%), Positives = 148/451 (32%), Gaps = 79/451 (17%)

Query: 41  AGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGG 100
           A     G G     S  S G G + S S     +   GT F  S SS       GP + G
Sbjct: 406 ASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS-------GPYVSG 458

Query: 101 KSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRR 160
                G            G TQ G  SG  + +     S SG     +   S +GSS   
Sbjct: 459 SGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG-SRSGQSSRGERQGSSAGSSSSY 517

Query: 161 AADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGS 220
              GS   Q          L  S +   SG+        + S    SS+Y          
Sbjct: 518 GQHGSGSRQ---------SLGHSRHGSGSGQSPSPSRGRHESGSRQSSSY---------- 558

Query: 221 LHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHG 280
                      G  G+G   G  SS  P   GSG     G   +  G    +  GY  HG
Sbjct: 559 -----------GPHGYGS--GRSSSRGPYESGSGHSSGLGHQESRSG----QSSGYGQHG 601

Query: 281 AE--------VNGGLPSASSFSSAPGATYGGVSSHTPPVSGA--DSLLGSRGTTAGSS-- 328
           +          +G     SS     GAT G  SSH    SG+   S  G +G+ +G S  
Sbjct: 602 SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPS 661

Query: 329 ----GDALGKALASIYSPDHSSNNFSSS---------PSTPVGSPQGLAGTSQWPRAGAP 375
               G   G   +S Y    S + +SSS          S+  G   G   +S + + G+ 
Sbjct: 662 RGRHGSDFGH--SSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSG 719

Query: 376 GALSPSY--DGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPM 433
            + S  Y   G   G  S+ E H   +     S + G  G       GHG   SG +G  
Sbjct: 720 SSHSSGYRKHGSRSGQSSRSEQHGSSS---GLSSSYGQHGSGSHQSSGHGRQGSG-SGHS 775

Query: 434 SLGGRHAGLVG--GSHPEDGLAGSTSLMHNH 462
               RH    G   SH + G   S S    H
Sbjct: 776 PSRVRHGSSSGHSSSHGQHGSGTSCSSSCGH 806


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 103/414 (24%), Positives = 134/414 (32%), Gaps = 47/414 (11%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
            PG  GK GE+G     G     G   + GF         PGP  P G  G     P   G
Sbjct: 652  PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGA----PGNDG 707

Query: 156  SSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFY 215
            +     A G+  +Q     +  PG   +   P    D G DA    +  +P         
Sbjct: 708  AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG-DAGPKGADGSPGKDGVRGL- 765

Query: 216  VADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGS----GPVGSSGSSSTFGGLHQH 271
               G + P     +P  +   GP    G +     PG     GP G +G +   G   Q 
Sbjct: 766  --TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823

Query: 272  ERMGYQLH-GAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGD 330
               G     GA+ + G P  +  +  PG   G V        GA    G+RG+       
Sbjct: 824  GAKGEPGDAGAKGDAGPPGPAGPAGPPG-PIGNV--------GAPGAKGARGSAGPPGAT 874

Query: 331  ALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQ 390
                A   +  P  S N     P  P G   G     +   AG PG + P    G  G +
Sbjct: 875  GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEK 934

Query: 391  SKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHA--GLVG--GS 446
                             A G AG   T  PG   +A G  G + L G+    G  G  G 
Sbjct: 935  GS-------------PGADGPAGAPGT--PGPQGIA-GQRGVVGLPGQRGERGFPGLPGP 978

Query: 447  HPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKRE 500
              E G  G +         P  P   P L+ PP      GR GA  A     R+
Sbjct: 979  SGEPGKQGPSGASGERG--PPGPMGPPGLAGPPGE---SGREGAPGAEGSPGRD 1027



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 80/326 (24%), Positives = 106/326 (32%), Gaps = 38/326 (11%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKG----TSQYYP 151
           PG  G  G  GA  + G     G     GF     A    GP  P G +G      +  P
Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP 375

Query: 152 SYSGSSRRRAADGSLDTQP-KKVRKVPPGLPSSV-YPPSSGEDYGRDATAYPSAKTPSST 209
                +   A +   D QP  K     PG+  +  +P + G    +     P  K  S  
Sbjct: 376 PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435

Query: 210 YPAPFYVAD----GSLHPSAELWSPPGQAGFGPMLGGGSSP----LPLPPG--------- 252
             AP    D    G   P   +  PPG AG     G    P    LP PPG         
Sbjct: 436 PGAPGSKGDTGAKGEPGP-VGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRG 494

Query: 253 -------SGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVS 305
                  +GP G +G   + G        G    G     GLP A   + +PG+      
Sbjct: 495 FPGADGVAGPKGPAGERGSPGPAGPKGSPGEA--GRPGEAGLPGAKGLTGSPGSPGPDGK 552

Query: 306 SHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAG 365
           +  P  +G D   G  G   G+ G A    +     P  ++     +    V  P G  G
Sbjct: 553 TGPPGPAGQDGRPGPPG-PPGARGQA---GVMGFPGPKGAAGEPGKAGERGVPGPPGAVG 608

Query: 366 -TSQWPRAGAPGALSPSYDGGLHGLQ 390
              +   AGA G   P+   G  G Q
Sbjct: 609 PAGKDGEAGAQGPPGPAGPAGERGEQ 634



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 81/295 (27%), Positives = 101/295 (34%), Gaps = 46/295 (15%)

Query: 97  GLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGS 156
           G  G+ G RG     GR    G     G      A   PGP  P+G  G    +P   G+
Sbjct: 296 GAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG----FPGAVGA 351

Query: 157 SRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYV 216
                  G   ++  +  +  PG P          + G D    P AK  +    AP  +
Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD--GQPGAKGANG---AP-GI 405

Query: 217 ADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGS-GPVGSSGSSSTFGGLHQHERMG 275
           A     P A   S P   G GP    G+S  P  PGS G  G+ G     G        G
Sbjct: 406 AGAPGFPGARGPSGPQGPG-GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG 464

Query: 276 YQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKA 335
            +  G     G P  +     PG   G  S   P   GAD + G +G  AG  G      
Sbjct: 465 EE--GKRGARGEPGPTGLPGPPGERGGPGSRGFP---GADGVAGPKG-PAGERG------ 512

Query: 336 LASIYSPDHSSNNFSSSPSTPVGSP--QGLAGTSQWPRA----GAPGALSPSYDG 384
                         S  P+ P GSP   G  G +  P A    G+PG  SP  DG
Sbjct: 513 --------------SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPG--SPGPDG 551



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 79/316 (25%), Positives = 106/316 (33%), Gaps = 33/316 (10%)

Query: 95   GPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGT-------- 146
            G G  G++G  G     G     G   + G    +    +PG   P G+ G         
Sbjct: 906  GKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPG 965

Query: 147  ---SQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSA 203
                + +P   G S      G      ++    P G P    PP    + GR+    P A
Sbjct: 966  QRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPG---ESGREGA--PGA 1020

Query: 204  KTPSSTYPAPFYVAD-GSLHPSAELWSP--PGQAG-FGPMLGGGSSPLPLPPG-SGPVGS 258
            +       +P    D G   P+    +P  PG  G  GP    G      P G +GPVG 
Sbjct: 1021 EGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP 1080

Query: 259  SGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLL 318
             G+    G   Q  R      G + + G+     FS   G      S      SGA    
Sbjct: 1081 VGARGPAG--PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPA 1138

Query: 319  GSRGT--TAGSSG-DALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAP 375
            G RG   +AG+ G D L      I  P        + P  P G P G  G    P AG  
Sbjct: 1139 GPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPG-PPGPPGPPGPPSAGFD 1197

Query: 376  GALSP------SYDGG 385
             +  P      ++DGG
Sbjct: 1198 FSFLPQPPQEKAHDGG 1213



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 80/326 (24%), Positives = 101/326 (30%), Gaps = 72/326 (22%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
            PG  G +G  G     G++ G G   + G       +  PGP  P+G KG+         
Sbjct: 886  PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP-------- 937

Query: 156  SSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFY 215
                  ADG            P G P +  P   G    R     P  +     +P    
Sbjct: 938  -----GADG------------PAGAPGT--PGPQGIAGQRGVVGLPGQRGERG-FP---- 973

Query: 216  VADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPL-PPG-SGPVGSSGSSSTFGGLHQHER 273
               G   PS E    PG+ G     G    P P+ PPG +GP G SG     G      R
Sbjct: 974  ---GLPGPSGE----PGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGR 1026

Query: 274  MGYQL----HGAEVNGGLPSASSFSSAPG----ATYGGVSSHTPPVSGADSL--LGSRGT 323
             G        G     G P A     APG    A   G    T P   A  +  +G+RG 
Sbjct: 1027 DGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP 1086

Query: 324  TA-----------GSSGDALGKALASIY----------SPDHSSNNFSSSPSTPVGSPQG 362
                         G  GD   K                SP     + +S P+ P G P  
Sbjct: 1087 AGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGS 1146

Query: 363  LAGTSQWPRAGAPGALSPSYDGGLHG 388
                 +    G PG + P    G  G
Sbjct: 1147 AGAPGKDGLNGLPGPIGPPGPRGRTG 1172



 Score = 37.0 bits (84), Expect = 0.057
 Identities = 73/298 (24%), Positives = 96/298 (32%), Gaps = 48/298 (16%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
           PGLGG    + +Y    +  G               ++ PGP+ PSG +G     P   G
Sbjct: 153 PGLGGNFAPQLSYGYDEKSTG--------------GISVPGPMGPSGPRG----LPGPPG 194

Query: 156 SSRRRAADGSLDTQPKKVRKVPPGLPSSVYPP-SSGEDYGRDATAYPSAKTPSSTYPAPF 214
           +   +   G      +     P G      PP  +G+D        P  + P    P P 
Sbjct: 195 APGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGP----PGP- 249

Query: 215 YVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERM 274
                 L  +A L    G  GF  + G      P    +GP G  GS    G   Q    
Sbjct: 250 -QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP----AGPKGEPGSPGENGAPGQMGPR 304

Query: 275 GYQLHGAEVNGGLPSASSFSSAPGAT-YGGVSSHTPPVS--GADSLLGSRGTTAGSSGDA 331
           G  L G     G P  +      GAT   G    T P    G    +G++G  AG  G  
Sbjct: 305 G--LPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKG-EAGPQGP- 360

Query: 332 LGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRA-GAPGALSPSYDGGLHG 388
                                P  P   P G AG +  P A G PGA   +   G+ G
Sbjct: 361 ---------RGSEGPQGVRGEPGPP--GPAGAAGPAGNPGADGQPGAKGANGAPGIAG 407



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 38/138 (27%), Positives = 49/138 (35%), Gaps = 22/138 (15%)

Query: 57   GSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAG 116
            G+ G         D   T  +G    + H   S      PG  G  GE+G   + G  AG
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQG-PPGPPGSPGEQGPSGASG-PAG 1139

Query: 117  VGGLTQAGFLSGELALNS-PGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRK 175
              G   +    G+  LN  PGP+ P G +G              R  D      P     
Sbjct: 1140 PRGPPGSAGAPGKDGLNGLPGPIGPPGPRG--------------RTGDAGPVGPPG---- 1181

Query: 176  VPPGLPSSVYPPSSGEDY 193
             PPG P    PPS+G D+
Sbjct: 1182 -PPGPPGPPGPPSAGFDF 1198


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 83/306 (27%), Positives = 98/306 (32%), Gaps = 32/306 (10%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
           PG GG  GE G     G     G     G   G+    +PG   P G+ G     P   G
Sbjct: 644 PGTGGPPGENGKPGEPGPKGDAGA---PGAPGGKGDAGAPGERGPPGLAGA----PGLRG 696

Query: 156 SSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAP- 213
            +     +G       K    PPG P +   P   G    R     P  K        P 
Sbjct: 697 GAGPPGPEGG------KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPG 750

Query: 214 ---FYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ 270
                  DG   P+  +  PPG AG     G G +P  LP  +GP GS G     G    
Sbjct: 751 ADGVPGKDGPRGPTGPI-GPPGPAGQPGDKGEGGAP-GLPGIAGPRGSPGERGETGPPGP 808

Query: 271 HERMGYQLHGAEVNG----GLPSASSFSSAPGAT--YGGVSSHTPPVSGADSLLGSRGTT 324
               G      E  G    G P        PG     GG     PP  G   + G RG+ 
Sbjct: 809 AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP--GPQGVKGERGSP 866

Query: 325 AGSSGDALGKALASIYSPDHSSNNFSSSPSTPVG--SPQGLAGTSQWPRAGAPGALSPSY 382
            G        A      P  + N     PS   G   P G AG +  P  G+PG   P  
Sbjct: 867 GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP--GSPGVSGPKG 924

Query: 383 DGGLHG 388
           D G  G
Sbjct: 925 DAGQPG 930



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 105/378 (27%), Positives = 132/378 (34%), Gaps = 79/378 (20%)

Query: 27   PLPVTNGKGRPASLAGAQFGGS-GLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESH 85
            P  V   +G P     A F G+ GL   P  GS G+      S  P +    G     + 
Sbjct: 856  PQGVKGERGSPGGPGAAGFPGARGLPGPP--GSNGNPGPPGPSGSPGKDGPPGP--AGNT 911

Query: 86   SSLSSSTFLGP-GLGGKSGERGAYASFGRDA-----GVGGLTQAGFLSGELALNSP-GPL 138
             +  S    GP G  G+ GE+G+  + G        G+ G+T A  L+G   +  P G  
Sbjct: 912  GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSP 971

Query: 139  SPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDAT 198
             P G+KG S   P  +G S  R   G            P GLP      ++GE  GRD  
Sbjct: 972  GPQGVKGESG-KPGANGLSGERGPPG------------PQGLPG--LAGTAGEP-GRDG- 1014

Query: 199  AYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPG-SGPVG 257
                   P S         DG   P  +  SP G+   G     G+   P  PG  GPVG
Sbjct: 1015 ------NPGS---------DGL--PGRD-GSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056

Query: 258  SSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSL 317
             +G S   G             G     G P  +    APG              GA  +
Sbjct: 1057 PAGKSGDRGE-----------SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI 1105

Query: 318  LGSRG-----TTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVG--SPQGLAGTSQWP 370
             G RG        GS G A      +I SP        + P  PVG   P G  GTS   
Sbjct: 1106 KGHRGFPGNPGAPGSPGPA--GQQGAIGSPG------PAGPRGPVGPSGPPGKDGTS--- 1154

Query: 371  RAGAPGALSPSYDGGLHG 388
              G PG + P    G  G
Sbjct: 1155 --GHPGPIGPPGPRGNRG 1170



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 116/456 (25%), Positives = 140/456 (30%), Gaps = 69/456 (15%)

Query: 97  GLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGS 156
           G  G +G RGA    GRD   GG    G         S G   P G +G S   P   G 
Sbjct: 510 GAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESG-RPGPPGP 568

Query: 157 SRRRAADGSL--------DTQP-KKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAK--- 204
           S  R   G +        D  P K   +  PG P    PP    + G      P+     
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGD 628

Query: 205 --TPSSTYPAPFYVADGSLHPSAELWSP--PGQAG--FGPMLGGGSSPLPLPPGSGPVGS 258
                   P       G+  P  E   P  PG  G    P   GG      P   GP G 
Sbjct: 629 KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688

Query: 259 SGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPG--ATYGGVSSHTPPVS---- 312
           +G+    GG       G +  GA    G P A+      G     GG+ S  P       
Sbjct: 689 AGAPGLRGGAGPPGPEGGK--GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEP 746

Query: 313 ---GADSLLGS---RGTTA-----------GSSGDALGKALASIYSPDHS-SNNFSSSPS 354
              GAD + G    RG T            G  G+     L  I  P  S      + P 
Sbjct: 747 GGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPP 806

Query: 355 TPVGSPQGLAGTSQWP----RAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVG 410
            P G P G  G +  P      GAPG        G+ G               ++     
Sbjct: 807 GPAGFP-GAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGS 865

Query: 411 TAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVG--GSHPEDGLAG-----------STS 457
             G      PG    A G  GP    G + G  G  GS  +DG  G             S
Sbjct: 866 PGGPGAAGFPG----ARGLPGPPGSNG-NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS 920

Query: 458 LMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAA 493
                A  P + G+ P    PP +   LG AG T A
Sbjct: 921 GPKGDAGQPGEKGS-PGAQGPPGAPGPLGIAGITGA 955



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 121/486 (24%), Positives = 146/486 (30%), Gaps = 153/486 (31%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGF-----LSGEL-------------------- 130
           PG  G  G  GA  S G+    G    AGF       GE+                    
Sbjct: 314 PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP 373

Query: 131 -----ALNSPGP------------LSPSGMKGT--------------SQYYPSYSGSSRR 159
                A   PGP            + P+G+ G               +   P   G +  
Sbjct: 374 QGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGE 433

Query: 160 RAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRD-------ATAYPSAK----TPSS 208
              +G+      +  +   G+P    P + GED G+D       A   P A      P  
Sbjct: 434 PGKNGAKGEPGPRGERGEAGIPG--VPGAKGED-GKDGSPGEPGANGLPGAAGERGAPGF 490

Query: 209 TYPAPFYVADGSLHPSAELWSP-----------PGQAGF--GPML--------GGGSSPL 247
             PA      G   P+ E  +P           PG+ G   GP +        G GS   
Sbjct: 491 RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550

Query: 248 PLPPGS-GPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSS 306
           P PPGS G  G  G     G   Q   MG+   G + N G P  +     PG   G    
Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFP--GPKGNDGAPGKNGERGGPG---GPGPQ 605

Query: 307 HTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGT 366
             P  +G     G  G T G  GD                    + P  P G  QGL GT
Sbjct: 606 GPPGKNGETGPQGPPGPT-GPGGD-----------------KGDTGPPGPQGL-QGLPGT 646

Query: 367 SQWP-RAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGAL 425
              P   G PG   P  D G  G                   A G  GD         A 
Sbjct: 647 GGPPGENGKPGEPGPKGDAGAPG-------------------APGGKGD---------AG 678

Query: 426 ASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGT--LPDLSRPPDSYS 483
           A G  GP  L G   GL GG+ P     G  +     A  P  PG    P L   P    
Sbjct: 679 APGERGPPGLAGA-PGLRGGAGPPGPEGGKGA-----AGPPGPPGAAGTPGLQGMPGERG 732

Query: 484 GLGRAG 489
           GLG  G
Sbjct: 733 GLGSPG 738



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 67/249 (26%), Positives = 83/249 (33%), Gaps = 53/249 (21%)

Query: 96   PGLGGKSGERGAYASFGRDA---------GVGGLTQAGFLSGELALNSPGPLSPSGMKGT 146
            PGL G +GE G   + G D          G G   + G      A   PGP  P G  G 
Sbjct: 1001 PGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGK 1060

Query: 147  SQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAK-- 204
            S      SG +    A G   ++     + P G          GE   R A      +  
Sbjct: 1061 SG-DRGESGPAGPAGAPGPAGSRGAPGPQGPRG--------DKGETGERGAAGIKGHRGF 1111

Query: 205  -----TPSSTYPAPFYVADGSLHPSAELWSPPGQAG-FGPMLGGGSSPLPLPPG-SGPVG 257
                  P S  PA    A GS  P+     P G  G  GP    G+S  P P G  GP G
Sbjct: 1112 PGNPGAPGSPGPAGQQGAIGSPGPA----GPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG 1167

Query: 258  SSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSL 317
            + G   +               G+  + G P       APG   GGV        GA ++
Sbjct: 1168 NRGERGS--------------EGSPGHPGQPGPPGPPGAPGPCCGGV--------GAAAI 1205

Query: 318  LGSRGTTAG 326
             G  G  AG
Sbjct: 1206 AGIGGEKAG 1214



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 38/156 (24%), Positives = 57/156 (36%), Gaps = 14/156 (8%)

Query: 29   PVTNGKGRPASLAG--AQFGGSGLEDRPS-SGSWGSGDQSSSSFDPSRTFSEGTHFTESH 85
            P   G   PA  +G   + G +G    P  +GS G+        D   T   G    + H
Sbjct: 1049 PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH 1108

Query: 86   SSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKG 145
                 +    PG  G +G++GA  S G     G +  +G    +     PGP+ P G + 
Sbjct: 1109 RGFPGNPG-APGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPR- 1166

Query: 146  TSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLP 181
                     G+   R ++GS     +     PPG P
Sbjct: 1167 ---------GNRGERGSEGSPGHPGQPGPPGPPGAP 1193


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 122/459 (26%), Positives = 143/459 (31%), Gaps = 103/459 (22%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGF-----------LSGELAL-NSPGPLSPSGM 143
            PG GGK G++G     G    VG   + GF           L G   L  +PG   P G 
Sbjct: 674  PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 733

Query: 144  KGT-----SQYYPSYSGSSRRRAADGSLDTQPKKVR-----KVPPGLPSSVYPPSSGEDY 193
             G      +Q  P   G    R A G     PK  R     K P G P        G+D 
Sbjct: 734  SGPAGPPGAQGPPGLQGMPGERGAAGI--AGPKGDRGDVGEKGPEGAP--------GKDG 783

Query: 194  GRDATAYPSAKTPSSTY----------PAPFYVADGSLHPSAELWSPPGQAGFGPMLGGG 243
            GR  T       P+             PA    A G+     E   PPG AGF    G  
Sbjct: 784  GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET-GPPGPAGFAGPPGAD 842

Query: 244  SSP--------------LPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPS 289
              P                 P   GP G+ G     G        G Q  G     G P 
Sbjct: 843  GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ--GPPGATGFPG 900

Query: 290  ASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTA--GSSGDALGKALASIYSPDHSSN 347
            A+     PG+         P  SG D   G+RG +   G +G+   +  A    P     
Sbjct: 901  AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG--PPGEKGE 958

Query: 348  NFSSSPSTPVG--SPQGLAG-------TSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLD 398
                 PS   G   PQGLAG         Q    G PG   PS + G  G          
Sbjct: 959  PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG---------- 1008

Query: 399  EAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHP--EDGLAGST 456
                     A G +GD     P       G TGP    GR  G  G   P   DG AG  
Sbjct: 1009 ---------APGASGDRG---PPGPVGPPGLTGPAGEPGRE-GSPGADGPPGRDGAAGVK 1055

Query: 457  SLMHNHAAL-----PSQPGTLPDLSRPPDSYSGLGRAGA 490
                   A+     P  PG+ P  + P       G AGA
Sbjct: 1056 GDRGETGAVGAPGAPGPPGS-PGPAGPTGKQGDRGEAGA 1093



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 95/376 (25%), Positives = 122/376 (32%), Gaps = 57/376 (15%)

Query: 29  PVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSL 88
           P   G+  P    G + G  G    P  G+ GS   + +S +P      G   +     +
Sbjct: 371 PGAKGEAGPTGARGPE-GAQGPRGEP--GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 427

Query: 89  SSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQ 148
           + +    PG  G  G +GA    G     G    AGF   +     PGP  P G      
Sbjct: 428 AGAPGF-PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA----- 481

Query: 149 YYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKT--- 205
             P  +G   +R A G    +P  V   P G P     P +    G+D  A P       
Sbjct: 482 --PGPAGEEGKRGARG----EPGGVG--PIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 533

Query: 206 -------PSSTYPAPFYVADGSLHPSAELWSPPGQAG----FGPMLGGGSSPLPLPPGSG 254
                  P      P    +  L  +  L   PG AG     GP    G    P PP  G
Sbjct: 534 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP--G 591

Query: 255 PVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGA 314
           P G+ G     G        G    G     GLP A      PG   G   +  PP  G 
Sbjct: 592 PQGARGQPGVMGFPGPKGANGEP--GKAGEKGLPGAPGLRGLPGKD-GETGAAGPP--GP 646

Query: 315 DSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP--QGLAGTSQWPRA 372
               G RG   G+ G +  + L                P    G P  QG+ G      A
Sbjct: 647 AGPAGERG-EQGAPGPSGFQGLPG-----------PPGPPGEGGKPGDQGVPG-----EA 689

Query: 373 GAPGALSPSYDGGLHG 388
           GAPG + P  + G  G
Sbjct: 690 GAPGLVGPRGERGFPG 705



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 103/363 (28%), Positives = 121/363 (33%), Gaps = 61/363 (16%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELA----LNSPGPLSPSGMKGTSQYYP 151
            PG  G++G  G  A F    G  G   A    GE        +PGP  PSG  G  Q   
Sbjct: 821  PGERGETGPPGP-AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP-QGPT 878

Query: 152  SYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYP 211
              +G    R A G             PG    V PP S  + G      PS K       
Sbjct: 879  GVTGPKGARGAQGPPGATGF------PGAAGRVGPPGSNGNPGPPGPPGPSGK------- 925

Query: 212  APFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPL--PPGSGPVGSSGSSSTFGGLH 269
                  DG      +   PPG+AG   + G    P     P   GP G+ G     G   
Sbjct: 926  ------DGPKGARGDS-GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 978

Query: 270  QHERMGYQLHGAEVNGGLPSASSFSSAPG--ATYGGVSSHTPPVS-GADSLLGSRGTTA- 325
            Q   +G  L G     G P     S  PG     G      PP   G   L G  G    
Sbjct: 979  QRGIVG--LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036

Query: 326  -GSSG--DALGKALASIYSPDHSSNNFSSSPSTP--VGSPQGLAGTS--QWPR--AGAPG 376
             GS G     G+  A+    D        +P  P   GSP G AG +  Q  R  AGA G
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP-GPAGPTGKQGDRGEAGAQG 1095

Query: 377  ALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALAS--GFTGPMS 434
             + PS   G  G+Q       D+          G AG+     PG   L    GFTG   
Sbjct: 1096 PMGPSGPAGARGIQGPQGPRGDK----------GEAGE-----PGERGLKGHRGFTGLQG 1140

Query: 435  LGG 437
            L G
Sbjct: 1141 LPG 1143



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 79/303 (26%), Positives = 104/303 (34%), Gaps = 38/303 (12%)

Query: 96   PGLGGKSGERGAYASFGRD--AGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSY 153
            PG  GK G +GA    G    AG  GL       GE     PG   PSG +G     P  
Sbjct: 920  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG--EPGDDGPSGAEGP----PGP 973

Query: 154  SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKT--PSSTYP 211
             G + +R   G +    ++  +  PGLP     P      G      P      P  T P
Sbjct: 974  QGLAGQR---GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030

Query: 212  APFYVADGSLHPSAELWSPPGQAGFGPMLG--GGSSPLPLPPGSGPVGSSGSSSTFGGLH 269
            A     +GS  P A+   PPG+ G   + G  G +  +  P   GP GS G +   G   
Sbjct: 1031 AGEPGREGS--PGAD--GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086

Query: 270  QHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSG 329
                 G Q     +    P+ +     P    G       P  G   L G RG T     
Sbjct: 1087 DRGEAGAQ---GPMGPSGPAGARGIQGPQGPRGDKGEAGEP--GERGLKGHRGFTG---- 1137

Query: 330  DALGKALASIYSPDHSSNNFSSS----PSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGG 385
                  L  +  P   S +  +S    PS P G P  +  + +    G PG + P    G
Sbjct: 1138 ------LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG 1191

Query: 386  LHG 388
              G
Sbjct: 1192 RSG 1194



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 104/408 (25%), Positives = 131/408 (32%), Gaps = 112/408 (27%)

Query: 96  PGLGGKSGERGAYASFGR--DAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSY 153
           PGL G  G RG     G   +AG  G+       GE    SPGP+ P G+ G  +     
Sbjct: 281 PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG--SPGPMGPRGLPG-ERGRTGP 337

Query: 154 SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
           +G++  R  DG    QP      P G P  V P       G      P AK         
Sbjct: 338 AGAAGARGNDG----QPG-----PAGPPGPVGPAG-----GPGFPGAPGAK--------- 374

Query: 214 FYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGS-GPVGSSGSSSTFGGLHQHE 272
                G   P+            GP    G    P  PGS GP G+SG+  T G      
Sbjct: 375 -----GEAGPT---------GARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG------ 414

Query: 273 RMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDAL 332
                + GA+ + G P  +     PG          P   GA   LG +G T G  G A 
Sbjct: 415 -----IPGAKGSAGAPGIAGAPGFPG------PRGPPGPQGATGPLGPKGQT-GEPGIAG 462

Query: 333 GKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSK 392
            K                  P+ P G+P       +    G PG + P    G  G    
Sbjct: 463 FKG--------EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERG---- 510

Query: 393 IEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRH--AGLVG--GSHP 448
                          A G  G      PG   LA    GP    G    +GL G  G++ 
Sbjct: 511 ---------------APGNRG-----FPGQDGLA----GPKGAPGERGPSGLAGPKGANG 546

Query: 449 EDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASE 496
           + G  G           P  PG      RP D+    G+ G + A  E
Sbjct: 547 DPGRPGE----------PGLPGARGLTGRPGDA-GPQGKVGPSGAPGE 583



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 68/252 (26%), Positives = 80/252 (31%), Gaps = 67/252 (26%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLS--GELAL----------NSPGPLSPSGM 143
            PGL G +GE G   S G D   G    AG     GE              SPGP  P+G 
Sbjct: 1025 PGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGK 1084

Query: 144  KGT-----SQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPG------------LPSSVYP 186
            +G      +Q     SG +  R   G    +  K     PG            L     P
Sbjct: 1085 QGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP 1144

Query: 187  PSSGEDYGRDATAYPSAKT--PSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGS 244
            P    D G    A PS     P    P+    A+G   P      PPG  G     G   
Sbjct: 1145 PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG----PPGPRGRSGETGPAG 1200

Query: 245  SP-LPLPPGS-GPVGSSGSSSTF----------------------GGLHQHERMGYQLHG 280
             P  P PPG  GP G     S F                      GGL QH+        
Sbjct: 1201 PPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHD-------- 1252

Query: 281  AEVNGGLPSASS 292
            AEV+  L S ++
Sbjct: 1253 AEVDATLKSLNN 1264



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 46/176 (26%), Positives = 57/176 (32%), Gaps = 27/176 (15%)

Query: 33   GKGRPASLAGAQ--FGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS 90
            GK      AGAQ   G SG      +G+ G         D       G    + H   + 
Sbjct: 1083 GKQGDRGEAGAQGPMGPSG-----PAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1137

Query: 91   STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYY 150
               L PG  G SG++GA    G     G     G    + A   PGP+ P G +G     
Sbjct: 1138 LQGL-PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR---- 1192

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTP 206
               SG +      G+            PG P    PP  G D    A   P  K P
Sbjct: 1193 ---SGETGPAGPPGN------------PGPPGPPGPPGPGIDMSAFAGLGPREKGP 1233


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 122/459 (26%), Positives = 143/459 (31%), Gaps = 103/459 (22%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGF-----------LSGELAL-NSPGPLSPSGM 143
            PG GGK G++G     G    VG   + GF           L G   L  +PG   P G 
Sbjct: 605  PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 664

Query: 144  KGT-----SQYYPSYSGSSRRRAADGSLDTQPKKVR-----KVPPGLPSSVYPPSSGEDY 193
             G      +Q  P   G    R A G     PK  R     K P G P        G+D 
Sbjct: 665  SGPAGPPGAQGPPGLQGMPGERGAAGI--AGPKGDRGDVGEKGPEGAP--------GKDG 714

Query: 194  GRDATAYPSAKTPSSTY----------PAPFYVADGSLHPSAELWSPPGQAGFGPMLGGG 243
            GR  T       P+             PA    A G+     E   PPG AGF    G  
Sbjct: 715  GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET-GPPGPAGFAGPPGAD 773

Query: 244  SSP--------------LPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPS 289
              P                 P   GP G+ G     G        G Q  G     G P 
Sbjct: 774  GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ--GPPGATGFPG 831

Query: 290  ASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTA--GSSGDALGKALASIYSPDHSSN 347
            A+     PG+         P  SG D   G+RG +   G +G+   +  A    P     
Sbjct: 832  AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG--PPGEKGE 889

Query: 348  NFSSSPSTPVG--SPQGLAG-------TSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLD 398
                 PS   G   PQGLAG         Q    G PG   PS + G  G          
Sbjct: 890  PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG---------- 939

Query: 399  EAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHP--EDGLAGST 456
                     A G +GD     P       G TGP    GR  G  G   P   DG AG  
Sbjct: 940  ---------APGASGDRG---PPGPVGPPGLTGPAGEPGRE-GSPGADGPPGRDGAAGVK 986

Query: 457  SLMHNHAAL-----PSQPGTLPDLSRPPDSYSGLGRAGA 490
                   A+     P  PG+ P  + P       G AGA
Sbjct: 987  GDRGETGAVGAPGAPGPPGS-PGPAGPTGKQGDRGEAGA 1024



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 95/376 (25%), Positives = 122/376 (32%), Gaps = 57/376 (15%)

Query: 29  PVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSL 88
           P   G+  P    G + G  G    P  G+ GS   + +S +P      G   +     +
Sbjct: 302 PGAKGEAGPTGARGPE-GAQGPRGEP--GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 358

Query: 89  SSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQ 148
           + +    PG  G  G +GA    G     G    AGF   +     PGP  P G      
Sbjct: 359 AGAPGF-PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA----- 412

Query: 149 YYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKT--- 205
             P  +G   +R A G    +P  V   P G P     P +    G+D  A P       
Sbjct: 413 --PGPAGEEGKRGARG----EPGGVG--PIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 464

Query: 206 -------PSSTYPAPFYVADGSLHPSAELWSPPGQAG----FGPMLGGGSSPLPLPPGSG 254
                  P      P    +  L  +  L   PG AG     GP    G    P PP  G
Sbjct: 465 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP--G 522

Query: 255 PVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGA 314
           P G+ G     G        G    G     GLP A      PG   G   +  PP  G 
Sbjct: 523 PQGARGQPGVMGFPGPKGANGEP--GKAGEKGLPGAPGLRGLPGKD-GETGAAGPP--GP 577

Query: 315 DSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSP--QGLAGTSQWPRA 372
               G RG   G+ G +  + L                P    G P  QG+ G      A
Sbjct: 578 AGPAGERG-EQGAPGPSGFQGLPG-----------PPGPPGEGGKPGDQGVPG-----EA 620

Query: 373 GAPGALSPSYDGGLHG 388
           GAPG + P  + G  G
Sbjct: 621 GAPGLVGPRGERGFPG 636



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 103/363 (28%), Positives = 121/363 (33%), Gaps = 61/363 (16%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELA----LNSPGPLSPSGMKGTSQYYP 151
            PG  G++G  G  A F    G  G   A    GE        +PGP  PSG  G  Q   
Sbjct: 752  PGERGETGPPGP-AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP-QGPT 809

Query: 152  SYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYP 211
              +G    R A G             PG    V PP S  + G      PS K       
Sbjct: 810  GVTGPKGARGAQGPPGATGF------PGAAGRVGPPGSNGNPGPPGPPGPSGK------- 856

Query: 212  APFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPL--PPGSGPVGSSGSSSTFGGLH 269
                  DG      +   PPG+AG   + G    P     P   GP G+ G     G   
Sbjct: 857  ------DGPKGARGDS-GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 909

Query: 270  QHERMGYQLHGAEVNGGLPSASSFSSAPG--ATYGGVSSHTPPVS-GADSLLGSRGTTA- 325
            Q   +G  L G     G P     S  PG     G      PP   G   L G  G    
Sbjct: 910  QRGIVG--LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 967

Query: 326  -GSSG--DALGKALASIYSPDHSSNNFSSSPSTP--VGSPQGLAGTS--QWPR--AGAPG 376
             GS G     G+  A+    D        +P  P   GSP G AG +  Q  R  AGA G
Sbjct: 968  EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP-GPAGPTGKQGDRGEAGAQG 1026

Query: 377  ALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALAS--GFTGPMS 434
             + PS   G  G+Q       D+          G AG+     PG   L    GFTG   
Sbjct: 1027 PMGPSGPAGARGIQGPQGPRGDK----------GEAGE-----PGERGLKGHRGFTGLQG 1071

Query: 435  LGG 437
            L G
Sbjct: 1072 LPG 1074



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 79/303 (26%), Positives = 104/303 (34%), Gaps = 38/303 (12%)

Query: 96   PGLGGKSGERGAYASFGRD--AGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSY 153
            PG  GK G +GA    G    AG  GL       GE     PG   PSG +G     P  
Sbjct: 851  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG--EPGDDGPSGAEGP----PGP 904

Query: 154  SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKT--PSSTYP 211
             G + +R   G +    ++  +  PGLP     P      G      P      P  T P
Sbjct: 905  QGLAGQR---GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 961

Query: 212  APFYVADGSLHPSAELWSPPGQAGFGPMLG--GGSSPLPLPPGSGPVGSSGSSSTFGGLH 269
            A     +GS  P A+   PPG+ G   + G  G +  +  P   GP GS G +   G   
Sbjct: 962  AGEPGREGS--PGAD--GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017

Query: 270  QHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSG 329
                 G Q     +    P+ +     P    G       P  G   L G RG T     
Sbjct: 1018 DRGEAGAQ---GPMGPSGPAGARGIQGPQGPRGDKGEAGEP--GERGLKGHRGFTG---- 1068

Query: 330  DALGKALASIYSPDHSSNNFSSS----PSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGG 385
                  L  +  P   S +  +S    PS P G P  +  + +    G PG + P    G
Sbjct: 1069 ------LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG 1122

Query: 386  LHG 388
              G
Sbjct: 1123 RSG 1125



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 104/408 (25%), Positives = 131/408 (32%), Gaps = 112/408 (27%)

Query: 96  PGLGGKSGERGAYASFGR--DAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSY 153
           PGL G  G RG     G   +AG  G+       GE    SPGP+ P G+ G  +     
Sbjct: 212 PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG--SPGPMGPRGLPG-ERGRTGP 268

Query: 154 SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
           +G++  R  DG    QP      P G P  V P       G      P AK         
Sbjct: 269 AGAAGARGNDG----QPG-----PAGPPGPVGPAG-----GPGFPGAPGAK--------- 305

Query: 214 FYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGS-GPVGSSGSSSTFGGLHQHE 272
                G   P+            GP    G    P  PGS GP G+SG+  T G      
Sbjct: 306 -----GEAGPT---------GARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG------ 345

Query: 273 RMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDAL 332
                + GA+ + G P  +     PG          P   GA   LG +G T G  G A 
Sbjct: 346 -----IPGAKGSAGAPGIAGAPGFPG------PRGPPGPQGATGPLGPKGQT-GEPGIAG 393

Query: 333 GKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSK 392
            K                  P+ P G+P       +    G PG + P    G  G    
Sbjct: 394 FKG--------EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERG---- 441

Query: 393 IEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRH--AGLVG--GSHP 448
                          A G  G      PG   LA    GP    G    +GL G  G++ 
Sbjct: 442 ---------------APGNRG-----FPGQDGLA----GPKGAPGERGPSGLAGPKGANG 477

Query: 449 EDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASE 496
           + G  G           P  PG      RP D+    G+ G + A  E
Sbjct: 478 DPGRPGE----------PGLPGARGLTGRPGDA-GPQGKVGPSGAPGE 514



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 68/252 (26%), Positives = 80/252 (31%), Gaps = 67/252 (26%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLS--GELAL----------NSPGPLSPSGM 143
            PGL G +GE G   S G D   G    AG     GE              SPGP  P+G 
Sbjct: 956  PGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGK 1015

Query: 144  KGT-----SQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPG------------LPSSVYP 186
            +G      +Q     SG +  R   G    +  K     PG            L     P
Sbjct: 1016 QGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP 1075

Query: 187  PSSGEDYGRDATAYPSAKT--PSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGS 244
            P    D G    A PS     P    P+    A+G   P      PPG  G     G   
Sbjct: 1076 PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG----PPGPRGRSGETGPAG 1131

Query: 245  SP-LPLPPGS-GPVGSSGSSSTF----------------------GGLHQHERMGYQLHG 280
             P  P PPG  GP G     S F                      GGL QH+        
Sbjct: 1132 PPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHD-------- 1183

Query: 281  AEVNGGLPSASS 292
            AEV+  L S ++
Sbjct: 1184 AEVDATLKSLNN 1195



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 46/176 (26%), Positives = 57/176 (32%), Gaps = 27/176 (15%)

Query: 33   GKGRPASLAGAQ--FGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSS 90
            GK      AGAQ   G SG      +G+ G         D       G    + H   + 
Sbjct: 1014 GKQGDRGEAGAQGPMGPSG-----PAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1068

Query: 91   STFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYY 150
               L PG  G SG++GA    G     G     G    + A   PGP+ P G +G     
Sbjct: 1069 LQGL-PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR---- 1123

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTP 206
               SG +      G+            PG P    PP  G D    A   P  K P
Sbjct: 1124 ---SGETGPAGPPGN------------PGPPGPPGPPGPGIDMSAFAGLGPREKGP 1164


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 123/484 (25%), Positives = 154/484 (31%), Gaps = 60/484 (12%)

Query: 34  KGRPASLAGAQFGGS-GLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSST 92
           KGRP         G  G+  +P +               SR FS      +  S L S  
Sbjct: 149 KGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQV 208

Query: 93  FLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTS--QYY 150
            L PG  G  G RG     G+  G G     G          PGP+ P G +G       
Sbjct: 209 GLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPG------EPGDPGPMGPIGSRGPEGPPGK 262

Query: 151 PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAK--TPSS 208
           P   G   R    G +        +  PG P     P      G      P  +   P S
Sbjct: 263 PGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGL---PGLKGHRGHKGLEGPKGEVGAPGS 319

Query: 209 TYPAPFYVADGSLHPSAELWSPPGQAGFGPMLG---GGSSPLPLPPG-SGPVGSSGSSST 264
              A      G++ P      P  +   GP       G+  +P  PG  GP+G  GSS  
Sbjct: 320 KGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGF 379

Query: 265 FGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTT 324
            G        G    GA    G P      + P    G  S   P   G D   G++G T
Sbjct: 380 PGNPGMKGEAGPT--GARGPEG-PQGQRGETGPPGPVG--SPGLPGAIGTDGTPGAKGPT 434

Query: 325 A--GSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRA-GAPGALSPS 381
              G+SG            P  +    S  P    G PQG+ G    P   G  G   P 
Sbjct: 435 GSPGTSG-----------PPGSAGPPGSPGPQGSTG-PQGIRGQPGDPGVPGFKGEAGPK 482

Query: 382 YDGGLHGLQSKIEDHLDEAIHVLRSH--AVGTAGDM-HTLLPGHGAL--ASGFTGPMSLG 436
            + G HG+Q  I    +E     R     VG  G +     PG+     + G  GP    
Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQ 542

Query: 437 GRHAGLVGGSHP-----------EDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGL 485
           G   G VG S P           E GL G+  L  N   +    G L  L  P +     
Sbjct: 543 GER-GPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN-PGVQGPEGKLGPLGAPGED---- 596

Query: 486 GRAG 489
           GR G
Sbjct: 597 GRPG 600



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 91/368 (24%), Positives = 112/368 (30%), Gaps = 56/368 (15%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGF---LSGELALNSPGPLSPSGMKGTSQYY-- 150
            PGL G  GERG   + G     GG+ + G       + A   PGPL P G  G +     
Sbjct: 758  PGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE 817

Query: 151  ---------PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYP 201
                     P   G+   R  +G          + P G P     P      G   +  P
Sbjct: 818  PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP 877

Query: 202  SAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLG--GGSSPLPLPPGSGPVGSS 259
                 S     P  V    L        PPG  GF    G  G   P   P  +GP+G  
Sbjct: 878  QGLAGSPGPHGPNGVP--GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935

Query: 260  GSS---STFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADS 316
            G        G    H R+     G     G P        PG   G      PP  G   
Sbjct: 936  GKEGPPGLRGDPGSHGRV-----GDRGPAGPPGGPGDKGDPGED-GQPGPDGPP--GPAG 987

Query: 317  LLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGT--SQWPRAGA 374
              G RG   G  G    + +  +  P  +      + +T    P G  G   S  P  G 
Sbjct: 988  TTGQRG-IVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGP-VGE 1045

Query: 375  PGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGAL-----ASGF 429
            PG   P+ + G  G                R  AVG  GD     PG   L     A G 
Sbjct: 1046 PGPEGPAGNDGTPG----------------RDGAVGERGDRGD--PGPAGLPGSQGAPGT 1087

Query: 430  TGPMSLGG 437
             GP+   G
Sbjct: 1088 PGPVGAPG 1095



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 116/472 (24%), Positives = 146/472 (30%), Gaps = 101/472 (21%)

Query: 57  GSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAG 116
           G  GS     S  DP R    G       +         PG+ G  G+ G   + G D  
Sbjct: 546 GPVGSSGPKGSQGDPGRPGEPGLPGARGLTG-------NPGVQGPEGKLGPLGAPGEDGR 598

Query: 117 VGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKV 176
            G     G      ++  PGP   SG  G     P  +G++      G+    P K  +V
Sbjct: 599 PGPPGSIGIRGQPGSMGLPGPKGSSGDPGK----PGEAGNAGVPGQRGA----PGKDGEV 650

Query: 177 PPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP--------------FYVADGSLH 222
            P  P  V PP    + G      P+        P P                 A G L 
Sbjct: 651 GPSGP--VGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLG 708

Query: 223 PSAELWSP-----------PGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQH 271
           P  E  +P           PG+ G    + GG  P       GP GS G S T G     
Sbjct: 709 PRGERGNPGERGEPGITGLPGEKG----MAGGHGP------DGPKGSPGPSGTPGDT--- 755

Query: 272 ERMGYQLHGAEVNGGLPSASSFSSAPG--ATYGGV----SSHTPPVSGADSLLGSRGT-- 323
                   G     G+P     +  PG     GG+    +  T    GA  L G  G   
Sbjct: 756 --------GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807

Query: 324 TAGSSGDALGKALASIYSPDHSSNNFSS----SPSTPVG-----SPQGLAGTSQWPRAGA 374
            AG +G+        +  P  S  N  S     P+  VG      P G  G    P  G 
Sbjct: 808 PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP--GE 865

Query: 375 PGALSPSYDGGLHGLQSKIEDHLDEAIHVLRS--------HAVGTAGDMHTLLPGHGALA 426
           PG    +   G  GL      H    +  L+          A G  G    + P   A A
Sbjct: 866 PGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGA 925

Query: 427 SGFTGPMSLGGRHA--GLVG--GSHPEDGLAGSTSLMHNHAALPSQPGTLPD 474
            G  GP+   G+    GL G  GSH   G  G        A  P  PG   D
Sbjct: 926 PGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP-------AGPPGGPGDKGD 970



 Score = 29.6 bits (65), Expect = 9.1
 Identities = 44/171 (25%), Positives = 56/171 (32%), Gaps = 34/171 (19%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
            PG  G  G +GA  + G     G   Q G         S GP+ P G  G  +  P   G
Sbjct: 1073 PGPAGLPGSQGAPGTPGPVGAPGDAGQRG------DPGSRGPIGPPGRAG-KRGLPGPQG 1125

Query: 156  SSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFY 215
                +   G    + +K  +   GL     PP             P+ +  S+  P PF 
Sbjct: 1126 PRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPG------------PNGEQGSAGIPGPFG 1173

Query: 216  VADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFG 266
                          PPG  G     G   +P PL P  GP G  GS    G
Sbjct: 1174 PR-----------GPPGPVG---PSGKEGNPGPLGP-IGPPGVRGSVGEAG 1209


>gi|22027580 alpha 1 type XIII collagen isoform 6 [Homo sapiens]
          Length = 702

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 85/313 (27%), Positives = 107/313 (34%), Gaps = 44/313 (14%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
           PGL G  G +G     G D  VG   Q G      A    GP  P G KG         G
Sbjct: 390 PGLPGPPGPKG---EAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGE-------PG 439

Query: 156 SSRRRAADGSLDTQPKKVRKV----PPGLPSSVYPPSS-------GE-----DYGRDATA 199
                  +G+++   +++R +    PPGLP  + PP +       GE       G D   
Sbjct: 440 KGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEK 499

Query: 200 YPSAKTPSSTYPAPFYV--ADGSLHPSAELWSP--PGQAGFGPMLGGGSSPLP-LPPGSG 254
            P  K      P P      DG      E   P  PG+ G     G   SP+P LP   G
Sbjct: 500 GPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEG 559

Query: 255 PVGSSGSSSTFG-----GLHQHE-RMGYQ-LHGAEVNGGLPSASSFSSAPGATYGGVSSH 307
           P G  G     G     GL   +   G+Q   G     GLP AS     PG         
Sbjct: 560 PPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIG 619

Query: 308 TPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTS 367
            P  +G     GS+G   G +G      L  ++ P     N           P+G  G  
Sbjct: 620 VPGPAGPKGERGSKG-DPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQ 678

Query: 368 QWPRAGAPGALSP 380
                GAPG  +P
Sbjct: 679 -----GAPGLDAP 686



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 76/319 (23%), Positives = 101/319 (31%), Gaps = 46/319 (14%)

Query: 93  FLGP-GLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYP 151
           F GP G  G  G++GA    GR   VG         G+  L+  GP  P G  GT + +P
Sbjct: 123 FQGPTGRPGLPGDKGAIGMPGR---VGS-------PGDAGLSIIGPRGPPGQPGT-RGFP 171

Query: 152 SYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSS----GEDYGRDA-TAYPSAKTP 206
            + G        G    +       PPG P            GE   R+  ++ P+A   
Sbjct: 172 GFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRS 231

Query: 207 SSTYPAPFYVADGSL----------------HPSAELWSPPGQAGFGPMLGGGSSPLPLP 250
           S            S+                   A +  PPG  G      G S PL  P
Sbjct: 232 SQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPG----PPGPSGPLGHP 287

Query: 251 PGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPP 310
              GP+G  G     G        GY  HG +   G+P       A GA    V+     
Sbjct: 288 GLPGPMGPPGLPGPPGPKGDPGIQGY--HGRKGERGMPGMPGKHGAKGAPGIAVAG---- 341

Query: 311 VSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAG-TSQW 369
           + G   + G++G         L   L        + N+       P   P GL G     
Sbjct: 342 MKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEP--GPPGLPGPPGPK 399

Query: 370 PRAGAPGALSPSYDGGLHG 388
             AG  G + P    G  G
Sbjct: 400 GEAGVDGQVGPPGQPGDKG 418


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 123/571 (21%), Positives = 191/571 (33%), Gaps = 98/571 (17%)

Query: 31   TNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSE-GTHFTESHSSLS 89
            T+ +   A+L+ A    SG+ +  S+     G   +++F  S T S      T SHSS  
Sbjct: 4085 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQG 4144

Query: 90   SS-TFLGPGLGGKSGERGAYASFGRDAG------------VGGLTQAGF----LSGELAL 132
            S+   L PG    S       +F    G              GL +A       +G L  
Sbjct: 4145 STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 4204

Query: 133  N-SPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSV---YPPS 188
              +P   + +G++  S  + S+  SS    +  S    P +V       PSS    +  +
Sbjct: 4205 TLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSA 4264

Query: 189  SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP-PGQAGFGPMLGGGSSPL 247
            S    GR   +     +P +T  A F        P+    S   G+    P+  G +   
Sbjct: 4265 SSTTLGRSEESTTVHSSPGATGTALF--------PTRSATSVLVGEPTTSPISSGSTETT 4316

Query: 248  PLPPGSGPVGSSGSSSTF------------------GGLHQHERMGYQLHGAEVNGGLPS 289
             LP  +   G S  S+TF                   G+ +     +   G+      PS
Sbjct: 4317 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPS 4376

Query: 290  ASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSG-------------------- 329
            +++    PG +    +SH+ P S  D+ L    TTA S G                    
Sbjct: 4377 STTM---PGVSQESTASHSSPGS-TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPD 4432

Query: 330  DALGKALASIYSPDHSSNNFSSSPSTPVGSP--QGLAGTSQ-WPRAGAPGALSPSYDGGL 386
            +     L    +P HSS     +  +P GS   QG + T Q WP +       P+     
Sbjct: 4433 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 4492

Query: 387  HGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGS 446
              L +              S +  T G        H +  +  T P       +GLV  S
Sbjct: 4493 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES 4552

Query: 447  HPEDGLAGSTSLMH----------------NHAA----LPSQPGTLPDLSRPPDSYSGLG 486
                   GST  MH                +H++    + S P T   L   P SY    
Sbjct: 4553 TTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 4612

Query: 487  RAGATAAASEIKREEKEDEENTSAADHSEEE 517
             + AT    +        EE+T++  HS ++
Sbjct: 4613 GSTATTHFPDSSTTSGRSEESTAS--HSSQD 4641



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 121/571 (21%), Positives = 189/571 (33%), Gaps = 98/571 (17%)

Query: 31   TNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSE-GTHFTESHSSLS 89
            T+ +   A+L+ A    SG+ +  S+     G   +++F  S T S      T SHSS  
Sbjct: 3002 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQG 3061

Query: 90   SS-TFLGPGLGGKSGERGAYASFGRDAG------------VGGLTQAGF----LSGELAL 132
            S+   L PG    S       +F    G              GL +A       +G L  
Sbjct: 3062 STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 3121

Query: 133  N-SPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSV---YPPS 188
              +P   + +G++  S  + S+  SS    +       P +V       PSS    +  +
Sbjct: 3122 TLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSA 3181

Query: 189  SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP-PGQAGFGPMLGGGSSPL 247
            S    GR   +     +P +T  A F        P+    S   G+    P+  G +   
Sbjct: 3182 SSTTLGRSEESTTVHSSPGATGTALF--------PTRSATSVLVGEPTTSPISSGSTETT 3233

Query: 248  PLPPGSGPVGSSGSSSTF------------------GGLHQHERMGYQLHGAEVNGGLPS 289
             LP  +   G S  S+TF                   G+ +     +   G+      P 
Sbjct: 3234 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 3293

Query: 290  ASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSG-------------------- 329
            +++    PG +    +SH+ P S  D+ L    TTA S G                    
Sbjct: 3294 STTM---PGVSQESTASHSSPGS-TDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPD 3349

Query: 330  DALGKALASIYSPDHSSNNFSSSPSTPVGSP--QGLAGTSQ-WPRAGAPGALSPSYDGGL 386
            +     L    +P HSS     +  +P GS   QG + T Q WP +       P+     
Sbjct: 3350 NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 3409

Query: 387  HGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGS 446
              L +              S +  T G        H +  +  T P       +GLV  S
Sbjct: 3410 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES 3469

Query: 447  HPEDGLAGSTSLMH----------------NHAA----LPSQPGTLPDLSRPPDSYSGLG 486
                   GST  MH                +H++    + S P T   L   P SY    
Sbjct: 3470 TTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 3529

Query: 487  RAGATAAASEIKREEKEDEENTSAADHSEEE 517
             + AT    +        EE+T++  HS ++
Sbjct: 3530 GSTATTHFPDSSTTSGRSEESTAS--HSSQD 3558



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 118/557 (21%), Positives = 181/557 (32%), Gaps = 90/557 (16%)

Query: 26   FPLPVTNGKGRPASLA----GAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFS-EGTH 80
            F  P T   G P+S+      A+   SGL +  ++     G   +  F  S T S  G  
Sbjct: 797  FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 856

Query: 81   FTESHSSLS-----------------SSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQA 123
             T SHSS +                 +S    PG    +    +  + GR         +
Sbjct: 857  STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 916

Query: 124  GFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVP----PG 179
               +G + L  P   + S + G S   P  SGS    A  GS  T     R       P 
Sbjct: 917  QDATGTIVL--PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPR 974

Query: 180  LPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVA--------------------DG 219
             P++   P+S    G    +  S   P ST+   F  +                    D 
Sbjct: 975  SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 1034

Query: 220  SLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLH 279
            +L P++   S P Q         GS+   L PGS    S G  ST    +          
Sbjct: 1035 TLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFP 1094

Query: 280  GAEVNGGLPSAS----SFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKA 335
             +  + G+  AS    S + +P  T    SS +P + G  +   +   +  ++      A
Sbjct: 1095 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 1154

Query: 336  LASIYSPDHSSNNFSSSP-STPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIE 394
             A    P   S  +  SP STP         T+ +P +              H  +S I 
Sbjct: 1155 TA----PVEESTTYHRSPGSTP---------TTHFPASSTTSG---------HSEKSTI- 1191

Query: 395  DHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAG 454
                   H     +  T    H+   G G      T  +S G      + GS    GL+ 
Sbjct: 1192 ------FHSSPDASGTTPSSAHSTTSGRG---ESTTSRISPGSTEITTLPGSTTTPGLSE 1242

Query: 455  STSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHS 514
            +++  ++    P  P T   LS    +  G+G    T+ +            +T+    S
Sbjct: 1243 ASTTFYSS---PRSPTT--TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS 1297

Query: 515  EEEKKELKAPRARTSST 531
            EE      + R  T +T
Sbjct: 1298 EESTTVYSSSRGSTETT 1314



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 93/360 (25%), Positives = 128/360 (35%), Gaps = 25/360 (6%)

Query: 13   DKELSDLLDFSMMFP-LPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDP 71
            D   S L + S  FP  P +   G PA+L  A  G        SSGS G+   S +    
Sbjct: 2430 DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-TLSPARSTT 2488

Query: 72   SRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELA 131
            S    E T    S SS  ++T  G        E+         +    L+ A   S  ++
Sbjct: 2489 SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 2548

Query: 132  LNSPGPLSPSGMKGTSQYYPSYS--GSSRR----RAADGSLDTQPKKVRKVPPGLPSSVY 185
              S    S  G   T+ +  S +  G SR      ++ GS DT          G PS   
Sbjct: 2549 EESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG-PSQES 2607

Query: 186  PPSSGEDYGRDATAYPSAKTPSS--TYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGG 243
              S       D    P + T  S       F+ + GS H +     P      G  +   
Sbjct: 2608 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL---FPDSTTSSG--IVEA 2662

Query: 244  SSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAP---GAT 300
            S+ +    GS     S +SST  GL Q E   +Q H A  +   PS  S ++AP     T
Sbjct: 2663 STRVHSSTGSPRTTLSPASSTSPGL-QGESTTFQTHPASTH-TTPSPPSTATAPVEESTT 2720

Query: 301  YGGVSSHTP----PVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTP 356
            Y      TP    P S   S    + T   SS DA G   +S +S        ++S  +P
Sbjct: 2721 YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 2780



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 113/522 (21%), Positives = 174/522 (33%), Gaps = 68/522 (13%)

Query: 39   SLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGT--HFTESHSSLSSS-TFLG 95
            +L+ A    SG+ +  ++     G   +++F PS T   G     T SHSS  S+ T L 
Sbjct: 4344 TLSPASTTSSGVSEESTTSHSRPGSMHTTAF-PSSTTMPGVSQESTASHSSPGSTDTTLS 4402

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLT---QAGFLSGELALNSPGPLSPSGMKGTSQYYPS 152
            PG    S       +F    G    T        SG L  ++P   S     G+     S
Sbjct: 4403 PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSST----GSPHTTLS 4458

Query: 153  YSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPA 212
             +GS+ R+    +  + P      P        PP++   +   +T   S  +PSST   
Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPA-------PPTTTSAFVELSTT--SHGSPSSTPTT 4509

Query: 213  PFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHE 272
             F  +  +L  S E                 S+ +   P +     S + ST  GL +  
Sbjct: 4510 HFSASSTTLGRSEE-----------------STTVHSSPVATATTPSPARSTTSGLVEES 4552

Query: 273  RMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDAL 332
               +   G+      P +++ S     +    SS T  +S A S   +      S   + 
Sbjct: 4553 TTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 4612

Query: 333  GKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGAL------SPSYDGGL 386
            G   A+ + PD S+ +  S  ST   S Q   GT   P       L      SP   G +
Sbjct: 4613 GST-ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 4671

Query: 387  H-----------GLQSKIEDHLDEAIHVLRSH---AVGTAGDMHTLLPGHGALASGFTGP 432
                        GL  K             +H   +  T G        H +  +  T P
Sbjct: 4672 ETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP 4731

Query: 433  MSLGGRHAGLVGGSHPEDGLAGSTSLMH----------NHAALPSQPGTLPDLSRPPDSY 482
                   +GLV  S       GST  MH          +  +  S   T   +S PP + 
Sbjct: 4732 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 4791

Query: 483  SGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAP 524
            S L     +  +S          E+++ +  SEE      +P
Sbjct: 4792 SALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSP 4833



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 89/372 (23%), Positives = 136/372 (36%), Gaps = 52/372 (13%)

Query: 29  PVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSL 88
           P+T+      +L G+    +GL ++ S+  + S      +  P+RT S G     S  S 
Sbjct: 256 PITSASMETTALPGSTTT-AGLSEK-STTFYSSPRSPDRTLSPARTTSSGV----SEKST 309

Query: 89  SSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALN-----SPGPLSPSGM 143
           +S +  GP             +F     + G++Q    S  +  +     SPG  +PS +
Sbjct: 310 TSHSRPGPT---------HTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSL 360

Query: 144 KGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVP----PGLPSSVYPPSSGEDYGRDATA 199
              S  + S  G ++      +  T        P     G P +   PSS   +  + T 
Sbjct: 361 GPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTT 420

Query: 200 YPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGG----GSSPLPLPPGSGP 255
           + S  +   T PAP       +  S    S P               G S    P  S P
Sbjct: 421 FQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSP 480

Query: 256 VGSS-----GSSSTFGGLHQHERMGY-QLHGAEVNGGLPSASSFS--SAPGATYGGVSSH 307
           V ++       S+T G  H  E   Y +  G+      P +S+ S  S   AT+ G ++H
Sbjct: 481 VATATTPPPARSATSG--HVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTH 538

Query: 308 ----TPPVSGA------DSLLGSRGTT-AGSSGDALGKALASIYSPDHSSNNFSSSPSTP 356
               TP  + A       S LGS  TT    S    G++  S     HSS +  ++   P
Sbjct: 539 TKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEES--KASHSSPDAMATTVLP 596

Query: 357 VGS-PQGLAGTS 367
            GS P  L G S
Sbjct: 597 AGSTPSVLVGDS 608



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 95/484 (19%), Positives = 162/484 (33%), Gaps = 25/484 (5%)

Query: 60   GSGDQSSSSFDPS-RTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVG 118
            G G++S++S   +  T S     T +     +S    PG    +    +  + GR     
Sbjct: 3492 GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 3551

Query: 119  GLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVP- 177
                +   +G + L  P   + S + G S   P  SGS    A  GS  T     +    
Sbjct: 3552 ASHSSQDATGTIVL--PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTF 3609

Query: 178  ---PGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQA 234
               P  P++   P+S    G    +  S   P ST+   F   D +  P     S    +
Sbjct: 3610 HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF--PDSTTTPGLSRHSTTSHS 3667

Query: 235  GFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFS 294
                   G +    LP  +   GSS  S+T                         +++F 
Sbjct: 3668 S-----PGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFH 3722

Query: 295  SAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPS 354
            S+PG+T+  +   +   SG         ++ GS    L  A ++       S  F + P+
Sbjct: 3723 SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 3782

Query: 355  TPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRS--HAVGTA 412
            +   +P   +  +           SP      H   S       E   +  S   A GT 
Sbjct: 3783 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 3842

Query: 413  -GDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPS---Q 468
                H+   G G      T  +S G      + GS    GL+ +++  ++    P+    
Sbjct: 3843 PSSAHSTTSGRG---ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 3899

Query: 469  PGTLPDLSRPPDSYSGLGRAGAT--AAASEIKREEKEDEENTSAADHSEEEKKELKAPRA 526
            P ++  L    +S +   + G+T    +          EE+T+    S    +    PR+
Sbjct: 3900 PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRS 3959

Query: 527  RTSS 530
             T+S
Sbjct: 3960 TTTS 3963



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 105/511 (20%), Positives = 165/511 (32%), Gaps = 75/511 (14%)

Query: 61   SGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGL 120
            S   S  S +   + S  TH   S  S +S+    P     S    A   F   +   G 
Sbjct: 1930 SSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 1989

Query: 121  TQAGFLS-------GELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKV 173
            ++    S       G + L  P   + S + G S   P  SGS    A  GS  T     
Sbjct: 1990 SEESTASHSSQDATGTIVL--PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 2047

Query: 174  RKVP----PGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVA------------ 217
            +       P  P++   P+S    G    +  S   P ST+   F  +            
Sbjct: 2048 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 2107

Query: 218  --------DGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLH 269
                    D +L P++   S P Q         GS+   L PGS    S G  ST     
Sbjct: 2108 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 2167

Query: 270  QHERMGYQLHGAEVNGGLPSAS----SFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTA 325
                       +  + G+  AS    S + +P  T    SS +P + G  +   +   + 
Sbjct: 2168 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 2227

Query: 326  GSSGDALGKALASIYSPDHSSNNFSSSP-STPVGSPQGLAGTSQWPRAGAPGALSPSYDG 384
             ++      A A    P   S  +  SP STP         T+ +P +            
Sbjct: 2228 HTTPSPPSTATA----PVEESTTYHRSPGSTP---------TTHFPASSTTSG------- 2267

Query: 385  GLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVG 444
              H  +S I        H     +  T    H+   G G      T  +S G      + 
Sbjct: 2268 --HSEKSTI-------FHSSPDASGTTPSSAHSTTSGRG---ESTTSRISPGSTEITTLP 2315

Query: 445  GSHPEDGLAGSTSLMHNHAALPS---QPGTLPDLSRPPDSYSGLGRAGAT--AAASEIKR 499
            GS    GL+ +++  ++    P+    P ++  L    +S +   + G+T    +     
Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2375

Query: 500  EEKEDEENTSAADHSEEEKKELKAPRARTSS 530
                 EE+T+    S    +    PR  T+S
Sbjct: 2376 TPGLSEESTTVYSSSPGSTETTVFPRTPTTS 2406



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 112/510 (21%), Positives = 171/510 (33%), Gaps = 67/510 (13%)

Query: 31   TNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSE-GTHFTESHSSLS 89
            T+ +   A+L+ A    SG+ +  S+     G   +++F  S T S+     T SHSS  
Sbjct: 1445 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 1504

Query: 90   SS-TFLGPGLGGKSG---ERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKG 145
            S+   L PG    S    +   + S   D     L      SG +  ++P   S   +  
Sbjct: 1505 STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 1564

Query: 146  TSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKT 205
            T    P+ S S+  +    +  + P      P        PP +       +T Y S   
Sbjct: 1565 TLT--PASSTSAGLQEESTTFQSWPSSSDTTPS-------PPGTTAAPVEVSTTYHSR-- 1613

Query: 206  PSSTYPAPFYVADGSLHPSAE---LWSPPGQAGFGPM-LGGGSSPLPLPPGSGPVGSSGS 261
            PSST    F  +  +L  S E   + S PG  G         +S L   P + P+ SSGS
Sbjct: 1614 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI-SSGS 1672

Query: 262  SSTFGGLHQHERMGYQLHGAEVNGGLPSASS-FSSAPGATYGGVSSHTPPVSGADSLLGS 320
            + T             L G+    GL   S+ F S+P +    +S    P S   S +  
Sbjct: 1673 TETTA-----------LPGSTTTAGLSEKSTTFYSSPRSPDTTLS----PASTTSSGVSE 1717

Query: 321  RGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSP 380
              TT+ S     G    + + P  ++    S  ST   S  G   T+  P +    +L P
Sbjct: 1718 ESTTSHSRP---GSTHTTAF-PGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP 1773

Query: 381  SYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHA 440
                                 H        + G   T L      ASG    +       
Sbjct: 1774 E----------------STTFH-------SSPGSTETTLLPDNTTASGL---LEASTPVH 1807

Query: 441  GLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKRE 500
               G  H     AGST+         S P +   +  PP + S       T+  S     
Sbjct: 1808 SSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTP 1867

Query: 501  EKEDEENTSAADHSEEEKKELKAPRARTSS 530
                  +++    SEE      +P A  ++
Sbjct: 1868 TTHFSASSTTLGRSEESTTVHSSPVATATT 1897



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 117/562 (20%), Positives = 174/562 (30%), Gaps = 55/562 (9%)

Query: 13   DKELSDLLDFSMMFP-LPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDP 71
            D   S L + S  FP  P +   G PA+L  A  G        SSGS G+   S +    
Sbjct: 2904 DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-TLSPARSTT 2962

Query: 72   SRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELA 131
            S    E T    S SS  ++T  G        E+         +    L+ A   S  ++
Sbjct: 2963 SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 3022

Query: 132  LNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLP--------SS 183
              S    S  G   T+ +  S + S   +    S  +Q      + PG          S+
Sbjct: 3023 EESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQST 3082

Query: 184  VYPPSSGEDYGRDATAYPSAKTPSSTYPA--PFYVADGSLHPSAELWSPPGQAGFG---- 237
             +  S G+    + T  P     S    A  P + + GSLH +    +P      G    
Sbjct: 3083 TFHSSPGDT---ETTLLPDDTITSGLVEASTPTHSSTGSLHTTL---TPASSTSAGLQEE 3136

Query: 238  ----PMLGGGSSPLPLPPG-----------------SGPVGSSGSSSTFGGLHQHERMGY 276
                      S   P PPG                 S P     +SST  G  +     +
Sbjct: 3137 STTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVH 3196

Query: 277  QLHGAEVNGGLPSASSFSSAPGA------TYGGVSSHTPPVSGADSLLGSRGTTAGSSGD 330
               GA      P+ S+ S   G       + G   +   P S   + L  + TT  SS  
Sbjct: 3197 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 3256

Query: 331  ALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLA--GTSQWPRAGAPGALSPSYDGGLHG 388
            +    L+   +     +  S++  +  GS    A  G++  P        S S  G    
Sbjct: 3257 SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT 3316

Query: 389  LQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHP 448
              S              +   G      TLLP +   ASG    +          G  H 
Sbjct: 3317 TLSPGSTTASSLGPESTTFHSGPGSTETTLLPDN-TTASGL---LEASTPVHSSTGSPHT 3372

Query: 449  EDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENT 508
                AGST+         S P +      PP + S       T+  S           ++
Sbjct: 3373 TLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS 3432

Query: 509  SAADHSEEEKKELKAPRARTSS 530
            +    SEE      +P A  ++
Sbjct: 3433 TTLGRSEESTTVHSSPVATATT 3454



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 111/521 (21%), Positives = 183/521 (35%), Gaps = 74/521 (14%)

Query: 21   DFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTH 80
            D +++     T+G  + ++ + +  G +     P S +  S  Q S++F  S   +  T 
Sbjct: 3673 DTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 3732

Query: 81   FTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSP 140
            F +S +S              SG   A        G    T            SP   + 
Sbjct: 3733 FPDSTTS--------------SGIVEASTRVHSSTGSPRTTL-----------SPASSTS 3767

Query: 141  SGMKGTSQYYPSYSGSSRRRAADGSLDTQPKK----VRKVPPGLPSSVYPPSS-GEDYGR 195
             G++G S  + ++  S+    +  S  T P +      + P   P++ +P SS    +  
Sbjct: 3768 PGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSE 3827

Query: 196  DATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGP 255
             +T + S+   S T P+       S H +    S  G++    +  G +    LP  +  
Sbjct: 3828 KSTIFHSSPDASGTTPS-------SAHSTT---SGRGESTTSRISPGSTEITTLPGSTTT 3877

Query: 256  VGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGAD 315
             G S +S+TF    +              G    +++  S PG+T+  VS    P S   
Sbjct: 3878 PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS----PASTTT 3933

Query: 316  SLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAP 375
              L    TT  SS    G    +++    +++     P+T    P     T     +   
Sbjct: 3934 PGLSEESTTVYSSSP--GSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTS 3991

Query: 376  GAL--SPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPM 433
            G    S ++ G     Q+ +   L  A            G+  T  P     +SG TG  
Sbjct: 3992 GLTEESTAFPGSPASTQTGLPATLTTA----------DLGEESTTFPS----SSGSTGTK 4037

Query: 434  SLGGRH--AGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDS-YSGLGRAGA 490
                R   +GLVG S P      ST        LP  P T P LS    + Y+      A
Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTET----TTLPGSP-TTPSLSEKSTTFYTSPRSPDA 4092

Query: 491  TAAASEIKREEKEDEENTSAADHSEEEKKELKA-PRARTSS 530
            T + +        +E +TS   HS+       A P + T+S
Sbjct: 4093 TLSPATTTSSGVSEESSTS---HSQPGSTHTTAFPDSTTTS 4130



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 93/468 (19%), Positives = 149/468 (31%), Gaps = 90/468 (19%)

Query: 134  SPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLD----TQPKKVRKVPPGLPSSVYPPSS 189
            SP   + SG+   S    S  GS+   A  GS      +Q        PG   +   P S
Sbjct: 1706 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS 1765

Query: 190  --GEDYGRDATAYPSAKTPSSTYPAPFYV-ADGSLHPSAELWSPPGQAGFGPMLGGGSSP 246
                  G ++T + S+   + T   P    A G L  S  + S  G            SP
Sbjct: 1766 TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTG------------SP 1813

Query: 247  LPLPPGSGPVGSSGSSSTFGGLHQHE--------------RMGYQLHGAEVNGGLPSASS 292
                  +G     G S+TF      +               +    HG+  +      S+
Sbjct: 1814 HTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 1873

Query: 293  FSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAG---------------------SSGDA 331
             S+  G +    + H+ PV+ A +   +R TT+G                      S  A
Sbjct: 1874 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTA 1933

Query: 332  LGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQS 391
             G++  S  S   +++  SS PST     +        P + A      S        +S
Sbjct: 1934 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 1993

Query: 392  KIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDG 451
                   +A   +   A  T   +         L    T P+S G      + GS    G
Sbjct: 1994 TASHSSQDATGTIVLPARSTTSVL---------LGESTTSPISSGSMETTALPGSTTTPG 2044

Query: 452  LAGSTSLMHNHAALP----------------------SQPGTLPDLSRPPDSYS-GLGRA 488
            L+  ++  H+    P                      S+PG+    + P  + + GL R 
Sbjct: 2045 LSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRH 2104

Query: 489  GATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSSTDEVLS 536
              T+ +S    +      +T+ +  S+E      +P     STD  LS
Sbjct: 2105 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSP----GSTDTALS 2148



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 82/400 (20%), Positives = 140/400 (35%), Gaps = 66/400 (16%)

Query: 134  SPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLD----TQPKKVRKVPPGLPSSVYPPSS 189
            SP   + SG+   S    S  GS+   A  GS      +Q        PG   +   P S
Sbjct: 3263 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS 3322

Query: 190  --GEDYGRDATAYPSAKTPSSTYPAPFYV-ADGSLHPSAELWSPPGQAGFGPMLGGGSSP 246
                  G ++T + S    + T   P    A G L  S  + S  G            SP
Sbjct: 3323 TTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTG------------SP 3370

Query: 247  LPLPPGSGPVGSSGSSSTFGGLHQHE--------------RMGYQLHGAEVNGGLPSASS 292
                  +G     G S+TF      +               +    HG+  +      S+
Sbjct: 3371 HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 3430

Query: 293  FSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAG-----SSGDALGKALASIYSPD---- 343
             S+  G +    + H+ PV+ A +   +R TT+G     ++  +   +  +++ P+    
Sbjct: 3431 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT 3490

Query: 344  -----HSSNNFSSSPSTPVGSPQGLAGTSQWPRA--GAPGALSPSYDGGLHGLQSKIEDH 396
                  S+ + SS+  T   +P   +   + P +   +PG+ + ++         + E+ 
Sbjct: 3491 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE- 3549

Query: 397  LDEAIHVLRSHAVGTAGDMHTLLPGHGA----LASGFTGPMSLGGRHAGLVGGSHPEDGL 452
               A H  +  A GT      +LP        L    T P+S G      + GS    GL
Sbjct: 3550 -STASHSSQD-ATGTI-----VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 3602

Query: 453  AGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATA 492
            +  ++  H+    P  P T   LS    + SG+     T+
Sbjct: 3603 SEKSTTFHSS---PRSPAT--TLSPASTTSSGVSEESTTS 3637



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 55/237 (23%), Positives = 82/237 (34%), Gaps = 18/237 (7%)

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPG------LPSSVYPPSSGEDYGRDATAYPSAK 204
            P  SG++   A   +         ++ PG      LP S   P   E      T Y S +
Sbjct: 1196 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE---ASTTFYSSPR 1252

Query: 205  TPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSST 264
            +P++T       + G    S    S PG           ++P  L   S  V SS   ST
Sbjct: 1253 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP-GLSEESTTVYSSSRGST 1311

Query: 265  FGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTT 324
               +  H      +HG E        ++F S P +T+  + +     SG      +   +
Sbjct: 1312 ETTVFPHSTTT-SVHGEE-------PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS 1363

Query: 325  AGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPS 381
              S+   L   L +    + S+   SSS ST        + TS       P  LSPS
Sbjct: 1364 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS 1420



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 23/167 (13%)

Query: 65   SSSSFDPSRTFS--EGTHFTESHSSLSSSTFLGPGLGGKSGE-RGAYASFGRDAGVGGLT 121
            SS S +P+  +S  E TH T   +S ++S     GL  +S        S       G +T
Sbjct: 4903 SSISGEPTSLYSQAESTHTTAFPASTTTS-----GLSQESTTFHSKPGSTETTLSPGSIT 4957

Query: 122  QAGFLS----------GELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPK 171
             + F              L+  SP   +  G+   S  + S  GS+   A   S      
Sbjct: 4958 TSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIH 5017

Query: 172  KVRKVP----PGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAP 213
              +  P    PG   +V P + +  D G+++TA+ S+   + T P P
Sbjct: 5018 SQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLP 5064


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 102/452 (22%), Positives = 152/452 (33%), Gaps = 56/452 (12%)

Query: 32  NGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSE------GTHFTESH 85
           +G   P+    A    SG    PS+  W S   S +S      ++        T      
Sbjct: 10  SGVSTPSGSGWASSSASGAST-PSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGW 68

Query: 86  SSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGF-LSGELALNSPGPLSPSGMK 144
           +S S+S    P   G +    ++AS   D+G    + +G  +  +    SP   S SG  
Sbjct: 69  ASFSASWASIPSDSGWASPSASWASTPSDSGWASPSASGASIPSDSGWASP---SVSGAS 125

Query: 145 GTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAK 204
             S ++ S S S     +D    +            PS+ +  +S +       A PSA 
Sbjct: 126 IPSAFWASPSASGASTPSDSGWAS------------PSASWASTSSDS----GWASPSAS 169

Query: 205 TPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSST 264
             S +       A G+  PS   W+ P      P     SSP      S P  S  +SS+
Sbjct: 170 WTSPSASCASSSASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSS 229

Query: 265 FGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVS---SHTPPVSGADSLLGSR 321
              +               +G   S+ S  ++P A++   S   + T   SG  S   S 
Sbjct: 230 ASCI-----------SPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASW 278

Query: 322 GTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPS 381
            +    SG     A  +  S   +S    S  S+P  S       S W    A GA +PS
Sbjct: 279 DSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPS 338

Query: 382 YDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAG 441
             G      S +    D       +    T+ D            SG+  P S       
Sbjct: 339 DSGWTSHSASGVSTTSDSGWASPSASGASTSSD------------SGWASP-SASWASPS 385

Query: 442 LVGGSHPEDGLAGSTSLMHNHAALPSQPGTLP 473
             G S P D  +G  S   + A++PS P   P
Sbjct: 386 ASGASTPSD--SGWASPSASGASMPSAPSLCP 415


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 65/242 (26%), Positives = 93/242 (38%), Gaps = 36/242 (14%)

Query: 224  SAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEV 283
            ++E    P  +G  P +GGGS+P    PG+   GS+G S+                    
Sbjct: 1607 TSERAGTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSA---------------GSITA 1651

Query: 284  NGGLPSASSFSSAPGAT-------YGGVSSHTPPVSGADSLLG-SRGTTAGSSGDALGKA 335
            + G  + SS SS  G T        G  SS      G   + G S G+TAGS  +   K 
Sbjct: 1652 SPGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKT 1711

Query: 336  LASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIED 395
              +  SP         SP +P G   G  GT++W      GA   +  G L   +  +E 
Sbjct: 1712 SFTGSSPPGKLTR--PSPGSP-GHFSG--GTTEWGNVATTGAAGENTSGALGSTEGSVEA 1766

Query: 396  HLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGS 455
                       +  GT+G   T  PG+ A++     P+   G   G  G S P +   G+
Sbjct: 1767 TTSAG----SGNTAGTSGTGDT-GPGNTAVSG---TPVVSPGATPGAPGSSTPGEADIGN 1818

Query: 456  TS 457
            TS
Sbjct: 1819 TS 1820



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 85/326 (26%), Positives = 131/326 (40%), Gaps = 60/326 (18%)

Query: 46   GGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGER 105
            GG         G+  SG    S+   S T S G   T S SS S +T  GP +GGK+G  
Sbjct: 1624 GGGSTPGEAGPGATVSGSTGVSA--GSITASPGASATSSESSKSGTT--GPSVGGKTGAT 1679

Query: 106  GAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGS 165
             + A+     G+ G+T            S G  + S  + T++   S++GSS        
Sbjct: 1680 SSEAT--SSEGMSGVTG----------QSLGSTAGSDSEITAK--TSFTGSS-------- 1717

Query: 166  LDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLH--P 223
                P K+ +  PG P   +      ++G  AT   + +  S    +     +GS+    
Sbjct: 1718 ---PPGKLTRPSPGSPG--HFSGGTTEWGNVATTGAAGENTSGALGS----TEGSVEATT 1768

Query: 224  SAELWSPPGQAGFGPMLGGGSSPLPLP---PGSGPVGSSGSS---------STFG--GLH 269
            SA   +  G +G G    G ++    P   PG+ P G+ GSS         ++FG  G  
Sbjct: 1769 SAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATP-GAPGSSTPGEADIGNTSFGKSGKS 1827

Query: 270  QHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSG-ADSLLGSRGTTAGSS 328
             H+ +        +N      +   SA   T   VS HT   S  A ++ GS+  T G+ 
Sbjct: 1828 GHDSL------TVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 1881

Query: 329  GDAL-GKALASIYSPDHSSNNFSSSP 353
            G A  G  + S +S   +S   S++P
Sbjct: 1882 GGATSGGKITSGWSSSGTSTGSSNTP 1907


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
            sapiens]
          Length = 2134

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 65/242 (26%), Positives = 93/242 (38%), Gaps = 36/242 (14%)

Query: 224  SAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEV 283
            ++E    P  +G  P +GGGS+P    PG+   GS+G S+                    
Sbjct: 1791 TSERAGTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSA---------------GSITA 1835

Query: 284  NGGLPSASSFSSAPGAT-------YGGVSSHTPPVSGADSLLG-SRGTTAGSSGDALGKA 335
            + G  + SS SS  G T        G  SS      G   + G S G+TAGS  +   K 
Sbjct: 1836 SPGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKT 1895

Query: 336  LASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIED 395
              +  SP         SP +P G   G  GT++W      GA   +  G L   +  +E 
Sbjct: 1896 SFTGSSPPGKLTR--PSPGSP-GHFSG--GTTEWGNVATTGAAGENTSGALGSTEGSVEA 1950

Query: 396  HLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGS 455
                       +  GT+G   T  PG+ A++     P+   G   G  G S P +   G+
Sbjct: 1951 TTSAG----SGNTAGTSGTGDT-GPGNTAVSG---TPVVSPGATPGAPGSSTPGEADIGN 2002

Query: 456  TS 457
            TS
Sbjct: 2003 TS 2004



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 85/326 (26%), Positives = 131/326 (40%), Gaps = 60/326 (18%)

Query: 46   GGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGER 105
            GG         G+  SG    S+   S T S G   T S SS S +T  GP +GGK+G  
Sbjct: 1808 GGGSTPGEAGPGATVSGSTGVSA--GSITASPGASATSSESSKSGTT--GPSVGGKTGAT 1863

Query: 106  GAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGS 165
             + A+     G+ G+T            S G  + S  + T++   S++GSS        
Sbjct: 1864 SSEAT--SSEGMSGVTG----------QSLGSTAGSDSEITAK--TSFTGSS-------- 1901

Query: 166  LDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLH--P 223
                P K+ +  PG P   +      ++G  AT   + +  S    +     +GS+    
Sbjct: 1902 ---PPGKLTRPSPGSPG--HFSGGTTEWGNVATTGAAGENTSGALGS----TEGSVEATT 1952

Query: 224  SAELWSPPGQAGFGPMLGGGSSPLPLP---PGSGPVGSSGSS---------STFG--GLH 269
            SA   +  G +G G    G ++    P   PG+ P G+ GSS         ++FG  G  
Sbjct: 1953 SAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATP-GAPGSSTPGEADIGNTSFGKSGKS 2011

Query: 270  QHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSG-ADSLLGSRGTTAGSS 328
             H+ +        +N      +   SA   T   VS HT   S  A ++ GS+  T G+ 
Sbjct: 2012 GHDSL------TVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 2065

Query: 329  GDAL-GKALASIYSPDHSSNNFSSSP 353
            G A  G  + S +S   +S   S++P
Sbjct: 2066 GGATSGGKITSGWSSSGTSTGSSNTP 2091


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
           sapiens]
          Length = 1691

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 122/452 (26%), Positives = 143/452 (31%), Gaps = 112/452 (24%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKG--------TS 147
           PGL G  G+RG+  + G  AG  GL               GPL PSG KG        T 
Sbjct: 509 PGLKGARGDRGSGGAQG-PAGAPGLV--------------GPLGPSGPKGKKGEPILSTI 553

Query: 148 QYYPSYSGSSRRRAADGSLDTQPK--------------------------------KVRK 175
           Q  P   G S  +   G +    K                                K   
Sbjct: 554 QGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHP 613

Query: 176 VPPGLPSSVYPPSSGE-----DYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP 230
            PPGLP +  P   G      D G+D          S     P  +  GS  PS      
Sbjct: 614 GPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLP-CIIPGSYGPSGF---- 668

Query: 231 PGQAGF-GPMLGGGSSPLPLPPGS-GPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLP 288
           PG  GF GP    GS  LP  PG  G  GS G   + G +H  E  G+   G     GLP
Sbjct: 669 PGTPGFPGPK---GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFP--GPRGEKGLP 723

Query: 289 SASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNN 348
               F   PG          P + G+  L GS+G T    G   G               
Sbjct: 724 ---GFPGLPG------KDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKG 774

Query: 349 FSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHA 408
           F      P     GL G       G PG L P  + G  G   ++            S  
Sbjct: 775 FLGDSGLP-----GLKGVH-----GKPGLLGPKGERGSPGTPGQVGQPGTPG----SSGP 820

Query: 409 VGTAGDMHTLLPGHGALASGFTG----PMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAA 464
            G  G   + LPG    A GF G    P   G R      GS  + GL G   L  N   
Sbjct: 821 YGIKG--KSGLPG----APGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGL 874

Query: 465 L-----PSQPGT--LPDLSRPPDSYSGLGRAG 489
           +     P  PG   LP LS P      +G  G
Sbjct: 875 VGLKGSPGSPGVAGLPALSGPKGEKGSVGFVG 906



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 87/325 (26%), Positives = 108/325 (33%), Gaps = 90/325 (27%)

Query: 96  PGLGGKSGERG-------AYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQ 148
           PGL G+ G +G       ++     D G+ GL   G    + A   PG + P+G  G   
Sbjct: 148 PGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLD--GITGPQGAPGFPGAVGPAGPPGLQ- 204

Query: 149 YYPSYSGSSRRRAADGS--LDTQPKKVRKVPPGLPSSVYPP-SSGEDYGRDATAYPSAKT 205
                 G       DG+  L  Q +K  K   GLP    PP S+GE    +   +P  K 
Sbjct: 205 ---GPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGE---LEFMGFPKGKK 258

Query: 206 PSSTYPAPFYVADGSLHPSAELWSPPGQAGFG-------------PMLGGGSSPLPLPPG 252
            S   P P      S         PPG  G G             P L G   P+     
Sbjct: 259 GSKGEPGPKGFPGIS--------GPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGV 310

Query: 253 SGPVGSSGSSSTFG--GLHQHERMGYQ-LHGAEVNGGLPSASSFSSAPGATYGGVSSHTP 309
            GP G  G   T G  GL+     G+Q + G + + GLP    F    GA   G +   P
Sbjct: 311 QGPPGQQGKKGTLGFPGLN-----GFQGIEGQKGDIGLPGPDVFIDIDGAVISG-NPGDP 364

Query: 310 PVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQW 369
            V G   L G  G                                      QGL G S  
Sbjct: 365 GVPGLPGLKGDEGI-------------------------------------QGLRGPSGV 387

Query: 370 PR----AGAPGALSPSYDGGLHGLQ 390
           P     +G PGAL P    GL G Q
Sbjct: 388 PGLPALSGVPGALGPQGFPGLKGDQ 412



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 112/435 (25%), Positives = 144/435 (33%), Gaps = 104/435 (23%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAG--------FLSGELAL-NSPGPLSPSGMKGT 146
            PG  G+ GE G   + GRD  +G +   G         +SG++ L  +PG    +GM+G 
Sbjct: 1081 PGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGE 1140

Query: 147  SQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTP 206
                P   GSS  + A G L +      K  PG P            G   T  PS    
Sbjct: 1141 ----PGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSI--- 1193

Query: 207  SSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFG 266
             +  P P           A L  P G+ G+              PG G +G+ G     G
Sbjct: 1194 -TGVPGP-----------AGLPGPKGEKGY--------------PGIG-IGAPGKPGLRG 1226

Query: 267  GLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAG 326
               Q    G+         GL   +    APG +   + +  P   G   L G RG   G
Sbjct: 1227 ---QKGDRGFP--------GLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG-RPG 1274

Query: 327  SSGDALGKALASIYSPDHSSNNFSS--SPSTPVGSPQGLAGTSQWPR------------- 371
             +G   G    S    D     F     P  P G  QG+ G S  P              
Sbjct: 1275 PAGPP-GPPGPSSNQGDTGDPGFPGIPGPKGPKGD-QGIPGFSGLPGELGLKGMRGEPGF 1332

Query: 372  AGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGF-- 429
             G PG + P  D G  G++ K               + G  GD     PG    A     
Sbjct: 1333 MGTPGKVGPPGDPGFPGMKGKAGPR----------GSSGLQGD-----PGQTPTAEAVQV 1377

Query: 430  -TGPMSLGGRHA--GLVG--GSHPEDGLAGSTSL-----MHNHAALPSQPGT-----LPD 474
              GP+ L G     GL G  G+    GL GS  L         + LP  PG      LP 
Sbjct: 1378 PPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPG 1437

Query: 475  LSRPPDSYSGLGRAG 489
            L  PP      G+ G
Sbjct: 1438 LQGPPGFEGAPGQQG 1452



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 88/329 (26%), Positives = 109/329 (33%), Gaps = 41/329 (12%)

Query: 95  GPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYS 154
           G GL G  G RG     G+D   G     G     L    PG   PSG  GT    P + 
Sbjct: 620 GNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT----PGFP 675

Query: 155 GSSRRRAADGSLDTQPKKVRKVPPGLPSSVY-PPSSGEDYGRDATAYPSAKTPSSTYPAP 213
           G    R   G+         K  PG P  V+ P   G    R     P           P
Sbjct: 676 GPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLP 735

Query: 214 FYVAD----GSLHPSAELW----SPPGQAGFGPMLGG----GSSPLP-------LPPGSG 254
             +      GS   + +++      PG+ G   + G     G S LP        P   G
Sbjct: 736 GMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG 795

Query: 255 PVGSSGSSSTFGGLHQHERMGYQ-LHGAEVNGGLPSASSFSSAPG--ATYGGVSSHTPPV 311
           P G  GS  T G + Q    G    +G +   GLP A  F    G     G      PP 
Sbjct: 796 PKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPG 855

Query: 312 S-------GADSLLGSRGTTA--GSSGDALGKALASIYSP--DHSSNNFSSSPSTPVGSP 360
           S       G   L G+ G     GS G      L ++  P  +  S  F   P  P G P
Sbjct: 856 SIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP-GLP 914

Query: 361 QGLAGTSQWPR-AGAPGALSPSYDGGLHG 388
            G+ GT       G+ G + PS   G  G
Sbjct: 915 -GIPGTRGLKGIPGSTGKMGPSGRAGTPG 942



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 88/344 (25%), Positives = 111/344 (32%), Gaps = 74/344 (21%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTS-------- 147
           PGL G +G +GA    G D G  GL     L G+        L+P   KG          
Sbjct: 121 PGLDGCNGTQGAVGFPGPD-GYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGL 179

Query: 148 ------QYYPSYSGSSRRRAADG-----------------SLDTQPKKVRKVPPGLPSSV 184
                 Q  P + G+       G                  L  Q +K  K   GLP   
Sbjct: 180 DGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPA 239

Query: 185 -YPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFG------ 237
             PPS+GE    +   +P  K  S   P P             +  PPG  G G      
Sbjct: 240 GPPPSTGE---LEFMGFPKGKKGSKGEPGP--------KGFPGISGPPGFPGLGTTGEKG 288

Query: 238 -------PMLGGGSSPLPLPPGSGPVGSSGSSSTFG--GLHQHERMGYQ-LHGAEVNGGL 287
                  P L G   P+      GP G  G   T G  GL+     G+Q + G + + GL
Sbjct: 289 EKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLN-----GFQGIEGQKGDIGL 343

Query: 288 PSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTA--GSSGDALGKALASI---YSP 342
           P    F    GA   G +   P V G   L G  G     G SG     AL+ +     P
Sbjct: 344 PGPDVFIDIDGAVISG-NPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGP 402

Query: 343 D--HSSNNFSSSPSTPVGSPQGLAGTSQWP-RAGAPGALSPSYD 383
                      +P        GL G    P   G PG  SP ++
Sbjct: 403 QGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFE 446



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 96/391 (24%), Positives = 128/391 (32%), Gaps = 59/391 (15%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLS-PSGMKGTSQYY---- 150
            PGL G  G RG     G    +G   +AG    +    +PGP+  PS  +  S  +    
Sbjct: 911  PGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGD 970

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTY 210
                GS+      G    + +  R  PPGLP +  P   G   G      P         
Sbjct: 971  KGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGA--PGLPGIIKGVSGKPGPPGFMGIRGL 1028

Query: 211  PAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ 270
            P         L  S+ +   PG  G     G   SP  LP  SG  G  G +        
Sbjct: 1029 P--------GLKGSSGITGFPGMPGESGSQGIRGSP-GLPGASGLPGLKGDNG------- 1072

Query: 271  HERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGD 330
                  ++ G+    G P  S F    G      +   P   G D  +G  G        
Sbjct: 1073 ---QTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAP 1129

Query: 331  ALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQ 390
                       P    ++       P+GSP GL G   +P  G PG        GL+GL 
Sbjct: 1130 GFPGVAGMRGEPGLPGSSGHQGAIGPLGSP-GLIGPKGFP--GFPGL------HGLNGLP 1180

Query: 391  SKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPED 450
                 H             GT G   T +PG     +G  GP    G + G+  G+  + 
Sbjct: 1181 GTKGTH-------------GTPGPSITGVPG----PAGLPGPKGEKG-YPGIGIGAPGKP 1222

Query: 451  GLAGSTS-----LMHNHAALPSQPG-TLPDL 475
            GL G         +   A LP  PG +LP L
Sbjct: 1223 GLRGQKGDRGFPGLQGPAGLPGAPGISLPSL 1253



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 72/300 (24%), Positives = 90/300 (30%), Gaps = 66/300 (22%)

Query: 97  GLGGKSGERG---AYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSY 153
           GL G  GERG       +G     G +   GFL        PG   P G  G        
Sbjct: 71  GLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPG-------- 122

Query: 154 SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
                    DG   TQ       P G P  + PP      G        +K      P  
Sbjct: 123 --------LDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKG--------SKGDPVLAPGS 166

Query: 214 F--YVADGSLHPSAELWSPPGQAGFGPMLGGGSSP-LPLPPG-SGPVGSSGSSSTFGGLH 269
           F     D  L     +  P G  GF   +G    P L  PPG  GP+G  G+        
Sbjct: 167 FKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMG------ 220

Query: 270 QHERMGYQ-LHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSS 328
               +G+Q   G + + GLP  +                 PP +G    +G      GS 
Sbjct: 221 ----LGFQGEKGVKGDVGLPGPAG---------------PPPSTGELEFMGFPKGKKGSK 261

Query: 329 GDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHG 388
           G+   K    I  P          P       +G  G    P  G PG   P    G+ G
Sbjct: 262 GEPGPKGFPGISGP-------PGFPGLGTTGEKGEKGEKGIP--GLPGPRGPMGSEGVQG 312


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
           sapiens]
          Length = 1690

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 122/452 (26%), Positives = 143/452 (31%), Gaps = 112/452 (24%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKG--------TS 147
           PGL G  G+RG+  + G  AG  GL               GPL PSG KG        T 
Sbjct: 508 PGLKGARGDRGSGGAQG-PAGAPGLV--------------GPLGPSGPKGKKGEPILSTI 552

Query: 148 QYYPSYSGSSRRRAADGSLDTQPK--------------------------------KVRK 175
           Q  P   G S  +   G +    K                                K   
Sbjct: 553 QGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHP 612

Query: 176 VPPGLPSSVYPPSSGE-----DYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP 230
            PPGLP +  P   G      D G+D          S     P  +  GS  PS      
Sbjct: 613 GPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLP-CIIPGSYGPSGF---- 667

Query: 231 PGQAGF-GPMLGGGSSPLPLPPGS-GPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLP 288
           PG  GF GP    GS  LP  PG  G  GS G   + G +H  E  G+   G     GLP
Sbjct: 668 PGTPGFPGPK---GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFP--GPRGEKGLP 722

Query: 289 SASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNN 348
               F   PG          P + G+  L GS+G T    G   G               
Sbjct: 723 ---GFPGLPG------KDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKG 773

Query: 349 FSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHA 408
           F      P     GL G       G PG L P  + G  G   ++            S  
Sbjct: 774 FLGDSGLP-----GLKGVH-----GKPGLLGPKGERGSPGTPGQVGQPGTPG----SSGP 819

Query: 409 VGTAGDMHTLLPGHGALASGFTG----PMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAA 464
            G  G   + LPG    A GF G    P   G R      GS  + GL G   L  N   
Sbjct: 820 YGIKG--KSGLPG----APGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGL 873

Query: 465 L-----PSQPGT--LPDLSRPPDSYSGLGRAG 489
           +     P  PG   LP LS P      +G  G
Sbjct: 874 VGLKGSPGSPGVAGLPALSGPKGEKGSVGFVG 905



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 87/325 (26%), Positives = 108/325 (33%), Gaps = 90/325 (27%)

Query: 96  PGLGGKSGERG-------AYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQ 148
           PGL G+ G +G       ++     D G+ GL   G    + A   PG + P+G  G   
Sbjct: 147 PGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLD--GITGPQGAPGFPGAVGPAGPPGLQ- 203

Query: 149 YYPSYSGSSRRRAADGS--LDTQPKKVRKVPPGLPSSVYPP-SSGEDYGRDATAYPSAKT 205
                 G       DG+  L  Q +K  K   GLP    PP S+GE    +   +P  K 
Sbjct: 204 ---GPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGE---LEFMGFPKGKK 257

Query: 206 PSSTYPAPFYVADGSLHPSAELWSPPGQAGFG-------------PMLGGGSSPLPLPPG 252
            S   P P      S         PPG  G G             P L G   P+     
Sbjct: 258 GSKGEPGPKGFPGIS--------GPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGV 309

Query: 253 SGPVGSSGSSSTFG--GLHQHERMGYQ-LHGAEVNGGLPSASSFSSAPGATYGGVSSHTP 309
            GP G  G   T G  GL+     G+Q + G + + GLP    F    GA   G +   P
Sbjct: 310 QGPPGQQGKKGTLGFPGLN-----GFQGIEGQKGDIGLPGPDVFIDIDGAVISG-NPGDP 363

Query: 310 PVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQW 369
            V G   L G  G                                      QGL G S  
Sbjct: 364 GVPGLPGLKGDEGI-------------------------------------QGLRGPSGV 386

Query: 370 PR----AGAPGALSPSYDGGLHGLQ 390
           P     +G PGAL P    GL G Q
Sbjct: 387 PGLPALSGVPGALGPQGFPGLKGDQ 411



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 112/435 (25%), Positives = 144/435 (33%), Gaps = 104/435 (23%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAG--------FLSGELAL-NSPGPLSPSGMKGT 146
            PG  G+ GE G   + GRD  +G +   G         +SG++ L  +PG    +GM+G 
Sbjct: 1080 PGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGE 1139

Query: 147  SQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTP 206
                P   GSS  + A G L +      K  PG P            G   T  PS    
Sbjct: 1140 ----PGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSI--- 1192

Query: 207  SSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFG 266
             +  P P           A L  P G+ G+              PG G +G+ G     G
Sbjct: 1193 -TGVPGP-----------AGLPGPKGEKGY--------------PGIG-IGAPGKPGLRG 1225

Query: 267  GLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAG 326
               Q    G+         GL   +    APG +   + +  P   G   L G RG   G
Sbjct: 1226 ---QKGDRGFP--------GLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG-RPG 1273

Query: 327  SSGDALGKALASIYSPDHSSNNFSS--SPSTPVGSPQGLAGTSQWPR------------- 371
             +G   G    S    D     F     P  P G  QG+ G S  P              
Sbjct: 1274 PAGPP-GPPGPSSNQGDTGDPGFPGIPGPKGPKGD-QGIPGFSGLPGELGLKGMRGEPGF 1331

Query: 372  AGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGF-- 429
             G PG + P  D G  G++ K               + G  GD     PG    A     
Sbjct: 1332 MGTPGKVGPPGDPGFPGMKGKAGPR----------GSSGLQGD-----PGQTPTAEAVQV 1376

Query: 430  -TGPMSLGGRHA--GLVG--GSHPEDGLAGSTSL-----MHNHAALPSQPGT-----LPD 474
              GP+ L G     GL G  G+    GL GS  L         + LP  PG      LP 
Sbjct: 1377 PPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPG 1436

Query: 475  LSRPPDSYSGLGRAG 489
            L  PP      G+ G
Sbjct: 1437 LQGPPGFEGAPGQQG 1451



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 88/329 (26%), Positives = 109/329 (33%), Gaps = 41/329 (12%)

Query: 95  GPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYS 154
           G GL G  G RG     G+D   G     G     L    PG   PSG  GT    P + 
Sbjct: 619 GNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT----PGFP 674

Query: 155 GSSRRRAADGSLDTQPKKVRKVPPGLPSSVY-PPSSGEDYGRDATAYPSAKTPSSTYPAP 213
           G    R   G+         K  PG P  V+ P   G    R     P           P
Sbjct: 675 GPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLP 734

Query: 214 FYVAD----GSLHPSAELW----SPPGQAGFGPMLGG----GSSPLP-------LPPGSG 254
             +      GS   + +++      PG+ G   + G     G S LP        P   G
Sbjct: 735 GMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG 794

Query: 255 PVGSSGSSSTFGGLHQHERMGYQ-LHGAEVNGGLPSASSFSSAPG--ATYGGVSSHTPPV 311
           P G  GS  T G + Q    G    +G +   GLP A  F    G     G      PP 
Sbjct: 795 PKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPG 854

Query: 312 S-------GADSLLGSRGTTA--GSSGDALGKALASIYSP--DHSSNNFSSSPSTPVGSP 360
           S       G   L G+ G     GS G      L ++  P  +  S  F   P  P G P
Sbjct: 855 SIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP-GLP 913

Query: 361 QGLAGTSQWPR-AGAPGALSPSYDGGLHG 388
            G+ GT       G+ G + PS   G  G
Sbjct: 914 -GIPGTRGLKGIPGSTGKMGPSGRAGTPG 941



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 88/344 (25%), Positives = 111/344 (32%), Gaps = 74/344 (21%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTS-------- 147
           PGL G +G +GA    G D G  GL     L G+        L+P   KG          
Sbjct: 120 PGLDGCNGTQGAVGFPGPD-GYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGL 178

Query: 148 ------QYYPSYSGSSRRRAADG-----------------SLDTQPKKVRKVPPGLPSSV 184
                 Q  P + G+       G                  L  Q +K  K   GLP   
Sbjct: 179 DGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPA 238

Query: 185 -YPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFG------ 237
             PPS+GE    +   +P  K  S   P P             +  PPG  G G      
Sbjct: 239 GPPPSTGE---LEFMGFPKGKKGSKGEPGP--------KGFPGISGPPGFPGLGTTGEKG 287

Query: 238 -------PMLGGGSSPLPLPPGSGPVGSSGSSSTFG--GLHQHERMGYQ-LHGAEVNGGL 287
                  P L G   P+      GP G  G   T G  GL+     G+Q + G + + GL
Sbjct: 288 EKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLN-----GFQGIEGQKGDIGL 342

Query: 288 PSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTA--GSSGDALGKALASI---YSP 342
           P    F    GA   G +   P V G   L G  G     G SG     AL+ +     P
Sbjct: 343 PGPDVFIDIDGAVISG-NPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGP 401

Query: 343 D--HSSNNFSSSPSTPVGSPQGLAGTSQWP-RAGAPGALSPSYD 383
                      +P        GL G    P   G PG  SP ++
Sbjct: 402 QGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFE 445



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 96/391 (24%), Positives = 128/391 (32%), Gaps = 59/391 (15%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLS-PSGMKGTSQYY---- 150
            PGL G  G RG     G    +G   +AG    +    +PGP+  PS  +  S  +    
Sbjct: 910  PGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGD 969

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTY 210
                GS+      G    + +  R  PPGLP +  P   G   G      P         
Sbjct: 970  KGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGA--PGLPGIIKGVSGKPGPPGFMGIRGL 1027

Query: 211  PAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQ 270
            P         L  S+ +   PG  G     G   SP  LP  SG  G  G +        
Sbjct: 1028 P--------GLKGSSGITGFPGMPGESGSQGIRGSP-GLPGASGLPGLKGDNG------- 1071

Query: 271  HERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGD 330
                  ++ G+    G P  S F    G      +   P   G D  +G  G        
Sbjct: 1072 ---QTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAP 1128

Query: 331  ALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQ 390
                       P    ++       P+GSP GL G   +P  G PG        GL+GL 
Sbjct: 1129 GFPGVAGMRGEPGLPGSSGHQGAIGPLGSP-GLIGPKGFP--GFPGL------HGLNGLP 1179

Query: 391  SKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPED 450
                 H             GT G   T +PG     +G  GP    G + G+  G+  + 
Sbjct: 1180 GTKGTH-------------GTPGPSITGVPG----PAGLPGPKGEKG-YPGIGIGAPGKP 1221

Query: 451  GLAGSTS-----LMHNHAALPSQPG-TLPDL 475
            GL G         +   A LP  PG +LP L
Sbjct: 1222 GLRGQKGDRGFPGLQGPAGLPGAPGISLPSL 1252



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 72/300 (24%), Positives = 90/300 (30%), Gaps = 66/300 (22%)

Query: 97  GLGGKSGERG---AYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSY 153
           GL G  GERG       +G     G +   GFL        PG   P G  G        
Sbjct: 70  GLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPG-------- 121

Query: 154 SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
                    DG   TQ       P G P  + PP      G        +K      P  
Sbjct: 122 --------LDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKG--------SKGDPVLAPGS 165

Query: 214 F--YVADGSLHPSAELWSPPGQAGFGPMLGGGSSP-LPLPPG-SGPVGSSGSSSTFGGLH 269
           F     D  L     +  P G  GF   +G    P L  PPG  GP+G  G+        
Sbjct: 166 FKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMG------ 219

Query: 270 QHERMGYQ-LHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSS 328
               +G+Q   G + + GLP  +                 PP +G    +G      GS 
Sbjct: 220 ----LGFQGEKGVKGDVGLPGPAG---------------PPPSTGELEFMGFPKGKKGSK 260

Query: 329 GDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHG 388
           G+   K    I  P          P       +G  G    P  G PG   P    G+ G
Sbjct: 261 GEPGPKGFPGISGP-------PGFPGLGTTGEKGEKGEKGIP--GLPGPRGPMGSEGVQG 311


>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
          Length = 1242

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 71/266 (26%), Positives = 101/266 (37%), Gaps = 32/266 (12%)

Query: 119  GLTQAGFLSGELALNS------PGPLSPSGMK---GTSQYYPSYSGSSRRRAADGSLDTQ 169
            G  Q+G+LSG +A +S      P  L P+  +   GT +Y     G  RR A   S   +
Sbjct: 902  GSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVE 961

Query: 170  PKKVRKVPPGLPSSVYP----PSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSA 225
              ++   PPG  S   P    PSS  DY     + P      ++  AP   AD     +A
Sbjct: 962  MGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAA 1021

Query: 226  ELWSPPGQAGFGPMLGGGSSPLPLPPG------------SGPVGSSGSSS-TFGGLHQHE 272
            E  S P            +S  P  P              GP G  G S+ T   L  + 
Sbjct: 1022 EEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNR 1081

Query: 273  RMGYQLHGAEVNG--GLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGD 330
                ++  A+  G     S+ +FSS P AT  G   +T P  GA + +G  G ++ SS D
Sbjct: 1082 NQSAKVIRADPQGCRRRHSSETFSSTPSATRVG---NTVPF-GAGAAVGGGGGSSSSSED 1137

Query: 331  ALGKALASIYSPDHSSNNFSSSPSTP 356
                + AS  +          +P  P
Sbjct: 1138 VKRHSSASFENVWLRPGELGGAPKEP 1163



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 87/369 (23%), Positives = 128/369 (34%), Gaps = 87/369 (23%)

Query: 151 PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGED-YGRDATAYPSAKTPSST 209
           PS  G +RR   +    T P  +    PG    V   S GE    R A+   S  +PS+ 
Sbjct: 294 PSQVGLTRRSRTESITATSPASMVGGKPG-SFRVRASSDGEGTMSRPASVDGSPVSPSTN 352

Query: 210 YP-APFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPL----PPGSGPVGSSGSSST 264
              A  +     LHP              P+    S P+P     P  + PV  S SS++
Sbjct: 353 RTHAHRHRGSARLHP--------------PLNHSRSIPMPASRCSPSATSPVSLSSSSTS 398

Query: 265 FGGLHQH----ERMGYQLHGAEVNGGLPSASSFSSAP---GATYGGVS----SHTPPVSG 313
             G         R    + G+  +GG  S+  + S+P    +++  V+     HTPP  G
Sbjct: 399 GHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARG 458

Query: 314 ADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAG 373
            + L  S     G  G +   A    Y      N    +P T +G+   LAG      A 
Sbjct: 459 EEEL--SNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAA- 515

Query: 374 APGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDM-HTLLPGHGALAS----- 427
                                  LD      R+H+ GT+  + H   P   ++AS     
Sbjct: 516 ----------------------DLDNRFR-KRTHSAGTSPTITHQKTPSQSSVASIEEYT 552

Query: 428 ---------GFTGPMSLGGRHAGLV-GGSHPEDGL-------------AGSTSLMHNHAA 464
                    G +G    G RH+  V   S+PE+GL               S++L  +   
Sbjct: 553 EMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGY 612

Query: 465 LPSQPGTLP 473
           +P  PG  P
Sbjct: 613 MPMSPGVAP 621


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
            sapiens]
          Length = 2134

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 65/242 (26%), Positives = 93/242 (38%), Gaps = 36/242 (14%)

Query: 224  SAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEV 283
            ++E    P  +G  P +GGGS+P    PG+   GS+G S+                    
Sbjct: 1791 TSERAGTPRVSGETPAVGGGSTPGEAGPGATVSGSTGVSA---------------GSITA 1835

Query: 284  NGGLPSASSFSSAPGAT-------YGGVSSHTPPVSGADSLLG-SRGTTAGSSGDALGKA 335
            + G  + SS SS  G T        G  SS      G   + G S G+TAGS  +   K 
Sbjct: 1836 SPGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKT 1895

Query: 336  LASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIED 395
              +  SP         SP +P G   G  GT++W      GA   +  G L   +  +E 
Sbjct: 1896 SFTGSSPPGKLTR--PSPGSP-GHFSG--GTTEWGNVATTGAAGENTSGALGSTEGSVEA 1950

Query: 396  HLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGS 455
                       +  GT+G   T  PG+ A++     P+   G   G  G S P +   G+
Sbjct: 1951 TTSAG----SGNTAGTSGTGDT-GPGNTAVSG---TPVVSPGATPGAPGSSTPGEADIGN 2002

Query: 456  TS 457
            TS
Sbjct: 2003 TS 2004



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 85/326 (26%), Positives = 131/326 (40%), Gaps = 60/326 (18%)

Query: 46   GGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGER 105
            GG         G+  SG    S+   S T S G   T S SS S +T  GP +GGK+G  
Sbjct: 1808 GGGSTPGEAGPGATVSGSTGVSA--GSITASPGASATSSESSKSGTT--GPSVGGKTGAT 1863

Query: 106  GAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGS 165
             + A+     G+ G+T            S G  + S  + T++   S++GSS        
Sbjct: 1864 SSEAT--SSEGMSGVTG----------QSLGSTAGSDSEITAK--TSFTGSS-------- 1901

Query: 166  LDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLH--P 223
                P K+ +  PG P   +      ++G  AT   + +  S    +     +GS+    
Sbjct: 1902 ---PPGKLTRPSPGSPG--HFSGGTTEWGNVATTGAAGENTSGALGS----TEGSVEATT 1952

Query: 224  SAELWSPPGQAGFGPMLGGGSSPLPLP---PGSGPVGSSGSS---------STFG--GLH 269
            SA   +  G +G G    G ++    P   PG+ P G+ GSS         ++FG  G  
Sbjct: 1953 SAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATP-GAPGSSTPGEADIGNTSFGKSGKS 2011

Query: 270  QHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSG-ADSLLGSRGTTAGSS 328
             H+ +        +N      +   SA   T   VS HT   S  A ++ GS+  T G+ 
Sbjct: 2012 GHDSL------TVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 2065

Query: 329  GDAL-GKALASIYSPDHSSNNFSSSP 353
            G A  G  + S +S   +S   S++P
Sbjct: 2066 GGATSGGKITSGWSSSGTSTGASNTP 2091


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 81/306 (26%), Positives = 98/306 (32%), Gaps = 36/306 (11%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGT-----SQYY 150
            PG  G +G  GA    G   GVG L   G         SPG     G+KG       +  
Sbjct: 1096 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1155

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAK-----T 205
                G        G       K    P G P    PP  G   G+D       +      
Sbjct: 1156 SGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1215

Query: 206  PSSTYPAPFYVADGSLHPSAELWSP--PGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSS 263
            P S  P       G L       SP   G+ G G    G    +  P  +GPVG +G + 
Sbjct: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG-GKGAKGDPGAIGAPGKTGPVGPAGPAG 1274

Query: 264  TFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT 323
                            G +   GLP +      PGAT  G +    PV G   L G RG 
Sbjct: 1275 K--------------PGPDGLRGLPGSVGQQGRPGAT--GQAGPPGPV-GPPGLPGLRG- 1316

Query: 324  TAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYD 383
             AG+ G+     L  +  P              +  PQG  G  Q    G PGA  P   
Sbjct: 1317 DAGAKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGPQGSPG--QKGEMGIPGASGPIGP 1371

Query: 384  GGLHGL 389
            GG  GL
Sbjct: 1372 GGPPGL 1377



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 122/526 (23%), Positives = 160/526 (30%), Gaps = 74/526 (14%)

Query: 29   PVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSL 88
            P   GK  PA L G   G  GL    ++G  G       S  P    S G    E  ++ 
Sbjct: 886  PGAPGKDGPAGLRGFP-GERGLPG--TAGGPGLKGNEGPSGPPGPAGSPG----ERGAAG 938

Query: 89   SSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQ 148
            S      PG  G  G  GA    G     G +   G    +  +  PGP  P G+ G   
Sbjct: 939  SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-- 996

Query: 149  YYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSS 208
                  G        G   T+  K    PPG P  + P   G+     A   P A+ P  
Sbjct: 997  -----DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP--VGQPGAAGADGEPGARGPQG 1049

Query: 209  TYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGL 268
             + A                   G  GF     G   P+ L    GP G  G +   G +
Sbjct: 1050 HFGAK---------------GDEGTRGF----NGPPGPIGLQGLPGPSGEKGETGDVGPM 1090

Query: 269  HQHERMGYQ----LHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT- 323
                  G +     +GA+   G P        PG       S +P + G   + G RG  
Sbjct: 1091 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150

Query: 324  ----TAGSSGDALGKALASIYSPDHSSNN-----FSSSPSTP-VGSPQGLAGT----SQW 369
                 +G  G+            D    N     F   P  P  G P+G  G      + 
Sbjct: 1151 GEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1210

Query: 370  PRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGF 429
               G PG+  P+ + G  G   K            R    G  GD     PG    A G 
Sbjct: 1211 GEPGQPGSPGPTGENGPPGPLGK-RGPAGSPGSEGRQGGKGAKGD-----PG-AIGAPGK 1263

Query: 430  TGPMSLGGRHAGLVGGSHPED--GLAGSTSLMHNHAAL-------PSQPGTLPDLSRPPD 480
            TGP+      AG  G   P+   GL GS        A        P  P  LP L     
Sbjct: 1264 TGPVG----PAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1319

Query: 481  SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRA 526
            +    G  G          + ++ +        S  +K E+  P A
Sbjct: 1320 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1365



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 83/328 (25%), Positives = 102/328 (31%), Gaps = 51/328 (15%)

Query: 97   GLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGT-----SQYYP 151
            GL GKSG RG     G     G     G    +      GP  P G +G         +P
Sbjct: 743  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802

Query: 152  SYSGSSRRRAADGSLDTQPKKVRKV-------PPGLPSSVYPP-SSGEDYGRDATAYPSA 203
               G       DG L   P +  +V       PPG P  V P  ++GE        +P  
Sbjct: 803  GPKGPPGPPGKDG-LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 861

Query: 204  KTPSSTYPAPFYV-------------ADGSLHPSAELWSP-----PGQAGFGPMLGGGSS 245
              P      P                A G   P+     P     PG AG GP L G   
Sbjct: 862  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG-GPGLKGNEG 920

Query: 246  PLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVS 305
            P   P  +G  G  G++ + G +    R G Q        G P A+     PG       
Sbjct: 921  PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ--------GPPGAAGEKGVPGEKGPIGP 972

Query: 306  SHTPPVSGADSLLGSRGT--TAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGL 363
            +    V G   L G  G    AG  GD        +  P       +     P G P  +
Sbjct: 973  TGRDGVQGPVGLPGPAGPPGVAGEDGDK-----GEVGDPGQKGTKGNKGEHGPPGPPGPI 1027

Query: 364  AGTSQWPRAGA---PGALSPSYDGGLHG 388
                Q   AGA   PGA  P    G  G
Sbjct: 1028 GPVGQPGAAGADGEPGARGPQGHFGAKG 1055



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 49/184 (26%), Positives = 62/184 (33%), Gaps = 30/184 (16%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTS--QYYPSY 153
            PG  GK G  G+  S GR  G G     G +         GP  P+G  G    +  P  
Sbjct: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287

Query: 154  SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYP-----------S 202
             G   R  A G     P  V   PPGLP        G+   +    +P            
Sbjct: 1288 VGQQGRPGATGQAG-PPGPVG--PPGLPG-----LRGDAGAKGEKGHPGLIGLIGPPGEQ 1339

Query: 203  AKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSS 262
             +      P P     GS     E+  P      GP   GG   LP P  +GP G+ G++
Sbjct: 1340 GEKGDRGLPGP----QGSPGQKGEMGIPGASGPIGP---GGPPGLPGP--AGPKGAKGAT 1390

Query: 263  STFG 266
               G
Sbjct: 1391 GPGG 1394



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/250 (26%), Positives = 80/250 (32%), Gaps = 46/250 (18%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQY--YPSY 153
           PGL G+SG+ G     G     G   +AG      A  + G     G+KG   +   P  
Sbjct: 421 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 480

Query: 154 SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
            G    R   G+             GLP    PP    + G D    P    P  + P  
Sbjct: 481 PGEKGHRGDTGA------------QGLPG---PPGEDGERGDDGEIGPRG-LPGESGPR- 523

Query: 214 FYVADGSLHPSAE--LWSPPGQAGF----GPMLGGGSSPLPLPPG-SGPVGSSGSSSTFG 266
                G L P     +  PPG  G     GP    G    P PPG  G  G+ G     G
Sbjct: 524 -----GLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 578

Query: 267 GLHQHERMGYQ----LHGAEVNGGLPSASSFSSAPGATYGGVSSHTPP----------VS 312
            +  H   G Q    L G   + G P        PG T G      P           V 
Sbjct: 579 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG-TKGNQGPSGPQGPLGYPGPRGVK 637

Query: 313 GADSLLGSRG 322
           G D + G +G
Sbjct: 638 GVDGIRGLKG 647



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 80/299 (26%), Positives = 94/299 (31%), Gaps = 49/299 (16%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
           PG  G+ GERG     G     G     G L         GP  P G+ G     P   G
Sbjct: 496 PGPPGEDGERGDDGEIGPRGLPGESGPRGLL---------GPKGPPGIPGP----PGVRG 542

Query: 156 SSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFY 215
               +   GSL  Q +       G P +   P      G      P  K      P    
Sbjct: 543 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG--- 599

Query: 216 VADGSL-HPSAELWSPPGQAG-FGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHER 273
            +DG   HP  E   PPG  G  GP   G   PL  P   G  G  G      GL  H+ 
Sbjct: 600 -SDGPPGHPGKE--GPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDG----IRGLKGHK- 649

Query: 274 MGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALG 333
                 G +   G P    F    G          P   G D   G +G T G +GD   
Sbjct: 650 ------GEKGEDGFP---GFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT-GPTGDPGP 699

Query: 334 KALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSK 392
             L      +         P  P    QG  G+  +P  G PGA   S + G  GL  K
Sbjct: 700 PGLMG----EKGKLGVPGLPGYP--GRQGPKGSLGFP--GFPGA---SGEKGARGLSGK 747


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 81/306 (26%), Positives = 98/306 (32%), Gaps = 36/306 (11%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGT-----SQYY 150
            PG  G +G  GA    G   GVG L   G         SPG     G+KG       +  
Sbjct: 1075 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1134

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAK-----T 205
                G        G       K    P G P    PP  G   G+D       +      
Sbjct: 1135 SGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1194

Query: 206  PSSTYPAPFYVADGSLHPSAELWSP--PGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSS 263
            P S  P       G L       SP   G+ G G    G    +  P  +GPVG +G + 
Sbjct: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG-GKGAKGDPGAIGAPGKTGPVGPAGPAG 1253

Query: 264  TFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT 323
                            G +   GLP +      PGAT  G +    PV G   L G RG 
Sbjct: 1254 K--------------PGPDGLRGLPGSVGQQGRPGAT--GQAGPPGPV-GPPGLPGLRG- 1295

Query: 324  TAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYD 383
             AG+ G+     L  +  P              +  PQG  G  Q    G PGA  P   
Sbjct: 1296 DAGAKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGPQGSPG--QKGEMGIPGASGPIGP 1350

Query: 384  GGLHGL 389
            GG  GL
Sbjct: 1351 GGPPGL 1356



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 122/526 (23%), Positives = 160/526 (30%), Gaps = 74/526 (14%)

Query: 29   PVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSL 88
            P   GK  PA L G   G  GL    ++G  G       S  P    S G    E  ++ 
Sbjct: 865  PGAPGKDGPAGLRGFP-GERGLPG--TAGGPGLKGNEGPSGPPGPAGSPG----ERGAAG 917

Query: 89   SSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQ 148
            S      PG  G  G  GA    G     G +   G    +  +  PGP  P G+ G   
Sbjct: 918  SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-- 975

Query: 149  YYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSS 208
                  G        G   T+  K    PPG P  + P   G+     A   P A+ P  
Sbjct: 976  -----DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP--VGQPGAAGADGEPGARGPQG 1028

Query: 209  TYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGL 268
             + A                   G  GF     G   P+ L    GP G  G +   G +
Sbjct: 1029 HFGAK---------------GDEGTRGF----NGPPGPIGLQGLPGPSGEKGETGDVGPM 1069

Query: 269  HQHERMGYQ----LHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT- 323
                  G +     +GA+   G P        PG       S +P + G   + G RG  
Sbjct: 1070 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1129

Query: 324  ----TAGSSGDALGKALASIYSPDHSSNN-----FSSSPSTP-VGSPQGLAGT----SQW 369
                 +G  G+            D    N     F   P  P  G P+G  G      + 
Sbjct: 1130 GEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1189

Query: 370  PRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGF 429
               G PG+  P+ + G  G   K            R    G  GD     PG    A G 
Sbjct: 1190 GEPGQPGSPGPTGENGPPGPLGK-RGPAGSPGSEGRQGGKGAKGD-----PG-AIGAPGK 1242

Query: 430  TGPMSLGGRHAGLVGGSHPED--GLAGSTSLMHNHAAL-------PSQPGTLPDLSRPPD 480
            TGP+      AG  G   P+   GL GS        A        P  P  LP L     
Sbjct: 1243 TGPVG----PAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1298

Query: 481  SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRA 526
            +    G  G          + ++ +        S  +K E+  P A
Sbjct: 1299 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1344



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 83/328 (25%), Positives = 102/328 (31%), Gaps = 51/328 (15%)

Query: 97   GLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGT-----SQYYP 151
            GL GKSG RG     G     G     G    +      GP  P G +G         +P
Sbjct: 722  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781

Query: 152  SYSGSSRRRAADGSLDTQPKKVRKV-------PPGLPSSVYPP-SSGEDYGRDATAYPSA 203
               G       DG L   P +  +V       PPG P  V P  ++GE        +P  
Sbjct: 782  GPKGPPGPPGKDG-LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840

Query: 204  KTPSSTYPAPFYV-------------ADGSLHPSAELWSP-----PGQAGFGPMLGGGSS 245
              P      P                A G   P+     P     PG AG GP L G   
Sbjct: 841  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG-GPGLKGNEG 899

Query: 246  PLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVS 305
            P   P  +G  G  G++ + G +    R G Q        G P A+     PG       
Sbjct: 900  PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ--------GPPGAAGEKGVPGEKGPIGP 951

Query: 306  SHTPPVSGADSLLGSRGT--TAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGL 363
            +    V G   L G  G    AG  GD        +  P       +     P G P  +
Sbjct: 952  TGRDGVQGPVGLPGPAGPPGVAGEDGDK-----GEVGDPGQKGTKGNKGEHGPPGPPGPI 1006

Query: 364  AGTSQWPRAGA---PGALSPSYDGGLHG 388
                Q   AGA   PGA  P    G  G
Sbjct: 1007 GPVGQPGAAGADGEPGARGPQGHFGAKG 1034



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 49/184 (26%), Positives = 62/184 (33%), Gaps = 30/184 (16%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTS--QYYPSY 153
            PG  GK G  G+  S GR  G G     G +         GP  P+G  G    +  P  
Sbjct: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266

Query: 154  SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYP-----------S 202
             G   R  A G     P  V   PPGLP        G+   +    +P            
Sbjct: 1267 VGQQGRPGATGQAG-PPGPVG--PPGLPG-----LRGDAGAKGEKGHPGLIGLIGPPGEQ 1318

Query: 203  AKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSS 262
             +      P P     GS     E+  P      GP   GG   LP P  +GP G+ G++
Sbjct: 1319 GEKGDRGLPGP----QGSPGQKGEMGIPGASGPIGP---GGPPGLPGP--AGPKGAKGAT 1369

Query: 263  STFG 266
               G
Sbjct: 1370 GPGG 1373



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/250 (26%), Positives = 80/250 (32%), Gaps = 46/250 (18%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQY--YPSY 153
           PGL G+SG+ G     G     G   +AG      A  + G     G+KG   +   P  
Sbjct: 400 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 459

Query: 154 SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
            G    R   G+             GLP    PP    + G D    P    P  + P  
Sbjct: 460 PGEKGHRGDTGA------------QGLPG---PPGEDGERGDDGEIGPRG-LPGESGPR- 502

Query: 214 FYVADGSLHPSAE--LWSPPGQAGF----GPMLGGGSSPLPLPPG-SGPVGSSGSSSTFG 266
                G L P     +  PPG  G     GP    G    P PPG  G  G+ G     G
Sbjct: 503 -----GLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 557

Query: 267 GLHQHERMGYQ----LHGAEVNGGLPSASSFSSAPGATYGGVSSHTPP----------VS 312
            +  H   G Q    L G   + G P        PG T G      P           V 
Sbjct: 558 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG-TKGNQGPSGPQGPLGYPGPRGVK 616

Query: 313 GADSLLGSRG 322
           G D + G +G
Sbjct: 617 GVDGIRGLKG 626



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 80/299 (26%), Positives = 94/299 (31%), Gaps = 49/299 (16%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
           PG  G+ GERG     G     G     G L         GP  P G+ G     P   G
Sbjct: 475 PGPPGEDGERGDDGEIGPRGLPGESGPRGLL---------GPKGPPGIPGP----PGVRG 521

Query: 156 SSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFY 215
               +   GSL  Q +       G P +   P      G      P  K      P    
Sbjct: 522 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG--- 578

Query: 216 VADGSL-HPSAELWSPPGQAG-FGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHER 273
            +DG   HP  E   PPG  G  GP   G   PL  P   G  G  G      GL  H+ 
Sbjct: 579 -SDGPPGHPGKE--GPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDG----IRGLKGHK- 628

Query: 274 MGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALG 333
                 G +   G P    F    G          P   G D   G +G T G +GD   
Sbjct: 629 ------GEKGEDGFP---GFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT-GPTGDPGP 678

Query: 334 KALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSK 392
             L      +         P  P    QG  G+  +P  G PGA   S + G  GL  K
Sbjct: 679 PGLMG----EKGKLGVPGLPGYP--GRQGPKGSLGFP--GFPGA---SGEKGARGLSGK 726


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 81/306 (26%), Positives = 98/306 (32%), Gaps = 36/306 (11%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGT-----SQYY 150
            PG  G +G  GA    G   GVG L   G         SPG     G+KG       +  
Sbjct: 1182 PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1241

Query: 151  PSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAK-----T 205
                G        G       K    P G P    PP  G   G+D       +      
Sbjct: 1242 SGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQ 1301

Query: 206  PSSTYPAPFYVADGSLHPSAELWSP--PGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSS 263
            P S  P       G L       SP   G+ G G    G    +  P  +GPVG +G + 
Sbjct: 1302 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG-GKGAKGDPGAIGAPGKTGPVGPAGPAG 1360

Query: 264  TFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT 323
                            G +   GLP +      PGAT  G +    PV G   L G RG 
Sbjct: 1361 K--------------PGPDGLRGLPGSVGQQGRPGAT--GQAGPPGPV-GPPGLPGLRG- 1402

Query: 324  TAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYD 383
             AG+ G+     L  +  P              +  PQG  G  Q    G PGA  P   
Sbjct: 1403 DAGAKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGPQGSPG--QKGEMGIPGASGPIGP 1457

Query: 384  GGLHGL 389
            GG  GL
Sbjct: 1458 GGPPGL 1463



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 122/526 (23%), Positives = 160/526 (30%), Gaps = 74/526 (14%)

Query: 29   PVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSL 88
            P   GK  PA L G   G  GL    ++G  G       S  P    S G    E  ++ 
Sbjct: 972  PGAPGKDGPAGLRGFP-GERGLPG--TAGGPGLKGNEGPSGPPGPAGSPG----ERGAAG 1024

Query: 89   SSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQ 148
            S      PG  G  G  GA    G     G +   G    +  +  PGP  P G+ G   
Sbjct: 1025 SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-- 1082

Query: 149  YYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSS 208
                  G        G   T+  K    PPG P  + P   G+     A   P A+ P  
Sbjct: 1083 -----DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP--VGQPGAAGADGEPGARGPQG 1135

Query: 209  TYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGL 268
             + A                   G  GF     G   P+ L    GP G  G +   G +
Sbjct: 1136 HFGAK---------------GDEGTRGF----NGPPGPIGLQGLPGPSGEKGETGDVGPM 1176

Query: 269  HQHERMGYQ----LHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGT- 323
                  G +     +GA+   G P        PG       S +P + G   + G RG  
Sbjct: 1177 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1236

Query: 324  ----TAGSSGDALGKALASIYSPDHSSNN-----FSSSPSTP-VGSPQGLAGT----SQW 369
                 +G  G+            D    N     F   P  P  G P+G  G      + 
Sbjct: 1237 GEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1296

Query: 370  PRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGF 429
               G PG+  P+ + G  G   K            R    G  GD     PG    A G 
Sbjct: 1297 GEPGQPGSPGPTGENGPPGPLGK-RGPAGSPGSEGRQGGKGAKGD-----PG-AIGAPGK 1349

Query: 430  TGPMSLGGRHAGLVGGSHPED--GLAGSTSLMHNHAAL-------PSQPGTLPDLSRPPD 480
            TGP+      AG  G   P+   GL GS        A        P  P  LP L     
Sbjct: 1350 TGPVG----PAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1405

Query: 481  SYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRA 526
            +    G  G          + ++ +        S  +K E+  P A
Sbjct: 1406 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1451



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 83/328 (25%), Positives = 102/328 (31%), Gaps = 51/328 (15%)

Query: 97   GLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGT-----SQYYP 151
            GL GKSG RG     G     G     G    +      GP  P G +G         +P
Sbjct: 829  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888

Query: 152  SYSGSSRRRAADGSLDTQPKKVRKV-------PPGLPSSVYPP-SSGEDYGRDATAYPSA 203
               G       DG L   P +  +V       PPG P  V P  ++GE        +P  
Sbjct: 889  GPKGPPGPPGKDG-LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 947

Query: 204  KTPSSTYPAPFYV-------------ADGSLHPSAELWSP-----PGQAGFGPMLGGGSS 245
              P      P                A G   P+     P     PG AG GP L G   
Sbjct: 948  PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG-GPGLKGNEG 1006

Query: 246  PLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVS 305
            P   P  +G  G  G++ + G +    R G Q        G P A+     PG       
Sbjct: 1007 PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ--------GPPGAAGEKGVPGEKGPIGP 1058

Query: 306  SHTPPVSGADSLLGSRGT--TAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGL 363
            +    V G   L G  G    AG  GD        +  P       +     P G P  +
Sbjct: 1059 TGRDGVQGPVGLPGPAGPPGVAGEDGDK-----GEVGDPGQKGTKGNKGEHGPPGPPGPI 1113

Query: 364  AGTSQWPRAGA---PGALSPSYDGGLHG 388
                Q   AGA   PGA  P    G  G
Sbjct: 1114 GPVGQPGAAGADGEPGARGPQGHFGAKG 1141



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 49/184 (26%), Positives = 62/184 (33%), Gaps = 30/184 (16%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTS--QYYPSY 153
            PG  GK G  G+  S GR  G G     G +         GP  P+G  G    +  P  
Sbjct: 1314 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1373

Query: 154  SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYP-----------S 202
             G   R  A G     P  V   PPGLP        G+   +    +P            
Sbjct: 1374 VGQQGRPGATGQAG-PPGPVG--PPGLPG-----LRGDAGAKGEKGHPGLIGLIGPPGEQ 1425

Query: 203  AKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSS 262
             +      P P     GS     E+  P      GP   GG   LP P  +GP G+ G++
Sbjct: 1426 GEKGDRGLPGP----QGSPGQKGEMGIPGASGPIGP---GGPPGLPGP--AGPKGAKGAT 1476

Query: 263  STFG 266
               G
Sbjct: 1477 GPGG 1480



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/250 (26%), Positives = 80/250 (32%), Gaps = 46/250 (18%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQY--YPSY 153
           PGL G+SG+ G     G     G   +AG      A  + G     G+KG   +   P  
Sbjct: 507 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 566

Query: 154 SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
            G    R   G+             GLP    PP    + G D    P    P  + P  
Sbjct: 567 PGEKGHRGDTGA------------QGLPG---PPGEDGERGDDGEIGPRG-LPGESGPR- 609

Query: 214 FYVADGSLHPSAE--LWSPPGQAGF----GPMLGGGSSPLPLPPG-SGPVGSSGSSSTFG 266
                G L P     +  PPG  G     GP    G    P PPG  G  G+ G     G
Sbjct: 610 -----GLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 664

Query: 267 GLHQHERMGYQ----LHGAEVNGGLPSASSFSSAPGATYGGVSSHTPP----------VS 312
            +  H   G Q    L G   + G P        PG T G      P           V 
Sbjct: 665 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG-TKGNQGPSGPQGPLGYPGPRGVK 723

Query: 313 GADSLLGSRG 322
           G D + G +G
Sbjct: 724 GVDGIRGLKG 733



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 80/299 (26%), Positives = 94/299 (31%), Gaps = 49/299 (16%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
           PG  G+ GERG     G     G     G L         GP  P G+ G     P   G
Sbjct: 582 PGPPGEDGERGDDGEIGPRGLPGESGPRGLL---------GPKGPPGIPGP----PGVRG 628

Query: 156 SSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFY 215
               +   GSL  Q +       G P +   P      G      P  K      P    
Sbjct: 629 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG--- 685

Query: 216 VADGSL-HPSAELWSPPGQAG-FGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHER 273
            +DG   HP  E   PPG  G  GP   G   PL  P   G  G  G      GL  H+ 
Sbjct: 686 -SDGPPGHPGKE--GPPGTKGNQGP--SGPQGPLGYPGPRGVKGVDG----IRGLKGHK- 735

Query: 274 MGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALG 333
                 G +   G P    F    G          P   G D   G +G T G +GD   
Sbjct: 736 ------GEKGEDGFP---GFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT-GPTGDPGP 785

Query: 334 KALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSK 392
             L      +         P  P    QG  G+  +P  G PGA   S + G  GL  K
Sbjct: 786 PGLMG----EKGKLGVPGLPGYP--GRQGPKGSLGFP--GFPGA---SGEKGARGLSGK 833


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 91/370 (24%), Positives = 128/370 (34%), Gaps = 47/370 (12%)

Query: 35   GRPASLAGAQFGGSGLEDRPSSGSWGSGD-QSSSSFDPSRTFSEGTHFTESHSSLSSSTF 93
            G+P+S   +Q+  SG      S S  S    SSSS   S           S S LSSS +
Sbjct: 1075 GKPSS--HSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMY 1132

Query: 94   LGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSY 153
               G  G S  + +  S G+  G   +T+ G  SG  +        PS +   S   P+ 
Sbjct: 1133 SSQGSSGSSQSKNSSQSGGK-PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNI 1191

Query: 154  SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
            S S  R    G  D     ++ VP   PSS                   AK+P S+    
Sbjct: 1192 SPSHSR--PPGGSDKLASPMKPVPGTPPSS------------------KAKSPISS---- 1227

Query: 214  FYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHER 273
                 G  H S    S  G      +   GS     PP S     + SSS+F        
Sbjct: 1228 ---GSGGSHMSGTS-SSSGMKSSSGLGSSGSLSQKTPPSSN--SCTASSSSFSSSGSSMS 1281

Query: 274  MGYQLHGAEVNGGLPSAS---SFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGD 330
                 HG+   G  PS +   S ++       GV +  P   G D L G  G +  SS  
Sbjct: 1282 SSQNQHGSS-KGKSPSRNKKPSLTAVIDKLKHGVVTSGP--GGEDPLDGQMGVSTNSSSH 1338

Query: 331  ALGK----ALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGA---LSPSYD 383
             +      +          S+   S  ST   S      TS+    G+ G    +   +D
Sbjct: 1339 PMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHD 1398

Query: 384  GGLHGLQSKI 393
            GG   +++K+
Sbjct: 1399 GGSPSIKAKV 1408



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 99/399 (24%), Positives = 146/399 (36%), Gaps = 67/399 (16%)

Query: 37   PASLAGAQFGGSGLEDRPSSGSWGSG---------DQSSSSF-----DPSRTFSEGTHFT 82
            PA L  A   GS   D P++  +  G          QS S F     D S    +   F 
Sbjct: 838  PADLI-ADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDF- 895

Query: 83   ESHSSLSSSTFLGPGLGGKSGERGAYASFGRDA------GVGGLTQAGFLSGELALNSPG 136
            +  +S + +T   P LGG +GE     +   D        V G   A     E    S G
Sbjct: 896  KGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQG 955

Query: 137  PLSPSGMKG---TSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDY 193
            PL  +G  G   T +     +G+S    +   LD++P K  + P     S   P   +  
Sbjct: 956  PLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKA 1015

Query: 194  GRDATAYPSAKTPSSTYPAPFYVADGSLHPSA--ELWSPPGQAGFGPMLGGGSSPLP--- 248
              +  + PS  + +  +  P     GS  P +     +PPG A         + P+P   
Sbjct: 1016 DTEGKS-PSHSSSNRPFTPPTSTG-GSKSPGSAGRSQTPPGVA---------TPPIPKIT 1064

Query: 249  --LPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSS 306
              +P G+  VG   S S +         G + H         S SS SS+  +T G + S
Sbjct: 1065 IQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHH--------SHSSSSSSSASTSGKMKS 1116

Query: 307  HTPPVSGADSLLGSRGTTAGSSGDAL--------GKALASIYSPDHSSNNFSSSPSTPVG 358
                 S +  L  S  ++ GSSG +         GK  +S  +    S+  SS+   P G
Sbjct: 1117 SKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQG 1176

Query: 359  SPQGLAGTSQWPRAGAPGALSPSYD---GGLHGLQSKIE 394
             P  L      P    P  +SPS+    GG   L S ++
Sbjct: 1177 KPSSLMN----PSLSKPN-ISPSHSRPPGGSDKLASPMK 1210



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 70/273 (25%), Positives = 101/273 (36%), Gaps = 29/273 (10%)

Query: 4    PQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGD 63
            P    P G   +L+     S M P+P T    +  S   +  GGS +    SS    SG 
Sbjct: 1193 PSHSRPPGGSDKLA-----SPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSS----SGM 1243

Query: 64   QSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVG---GL 120
            +SSS    S + S+ T  + +  + SSS+F   G    S +    +S G+         L
Sbjct: 1244 KSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSL 1303

Query: 121  TQA-GFLSGELALNSPGPLSP-SGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPP 178
            T     L   +  + PG   P  G  G S    S+  SS+   + G    + +K  K   
Sbjct: 1304 TAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKD-- 1361

Query: 179  GLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVA--DG---SLHPSAELWSPPGQ 233
               S V    S  D  +  +    +K   ST  A   ++  DG   S+     L  P   
Sbjct: 1362 --KSKVSTSGSSVDSSKKTS---ESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGES 1416

Query: 234  AGFG---PMLGGGSSPLPLPPGSGPVGSSGSSS 263
            +G G    M    +   PL  GS P    GS S
Sbjct: 1417 SGEGLRPQMASSKNYGSPLISGSTPKHERGSPS 1449


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 83/289 (28%), Positives = 96/289 (33%), Gaps = 47/289 (16%)

Query: 98  LGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSS 157
           L G  G +G   S G   G  G      + G L    PGP  P G KG S   P   G  
Sbjct: 565 LRGSPGPKGDMGSPG-PKGDRGFPGTPGIPGPLG--HPGPQGPKGQKG-SVGDPGMEGPM 620

Query: 158 RRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVA 217
            +R  +G            P G      PP SGE   R A   P    P           
Sbjct: 621 GQRGREG------------PMGPRGEAGPPGSGEKGERGAAGEPGPHGPPG--------V 660

Query: 218 DGSLHPSAELWSPPGQAGFGPM-LGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGY 276
            GS+ P     SP  Q   GP+ L G    + LP   G  G  G     G   Q E+   
Sbjct: 661 PGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKG--DQGEKGPR 718

Query: 277 QLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKAL 336
            L G     GLP A     A GA            +G D   G RG   G +G      +
Sbjct: 719 GLTGEPGMRGLPGAVGEPGAKGAM---------GPAGPDGHQGPRG-EQGLTG------M 762

Query: 337 ASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWP----RAGAPGALSPS 381
             I  P   S +      T    PQGL GT   P      GAPG +  S
Sbjct: 763 PGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTS 811



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 82/328 (25%), Positives = 107/328 (32%), Gaps = 89/328 (27%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSP-------------GPLSPSG 142
            PG  G+ G +GA    G D   G   + G L+G   +  P             GP  P G
Sbjct: 730  PGAVGEPGAKGAMGPAGPDGHQGPRGEQG-LTGMPGIRGPPGPSGDPGKPGLTGPQGPQG 788

Query: 143  MKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKV---PPGLPSSVYPPSSGEDYGRDATA 199
            + GT    P   G      A G + T           PPG P ++ PP            
Sbjct: 789  LPGT----PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGP---------- 834

Query: 200  YPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAG----FGPMLGGGSSP-------LP 248
             P A  P+     P +           L  PPG  G     GP + G   P       LP
Sbjct: 835  -PGAPGPAGPAGLPGH------QEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLP 887

Query: 249  LPPG-------------SGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSS 295
             PPG             SGP G  G     G        G+Q  G +   GLP    FS+
Sbjct: 888  GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQ--GEQ---GLP---GFST 939

Query: 296  APGATYGGVSSHTPPVSGADSLLGSRGT--TAGSSGDALGKALASIYSPDHSSNNFSSSP 353
            +  +++G      P   G     G +G     G+ G   G +         SS  + S P
Sbjct: 940  SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPS-----EGGSSSTMYVSGP 994

Query: 354  STPVGSPQGLAGTSQWPRAGAPGALSPS 381
              P G P            G PG++S S
Sbjct: 995  PGPPGPP------------GPPGSISSS 1010



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 79/299 (26%), Positives = 106/299 (35%), Gaps = 57/299 (19%)

Query: 89   SSSTFLG-----PGLGGKSGERGAYASFGR--DAGVGGLTQAGFLSGELALNSP-GPLSP 140
            +S TFL      PG  G  G++G     G   + G+ G + +G  S  L L  P GP  P
Sbjct: 899  NSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGP 958

Query: 141  SGMKGTS--QYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDAT 198
             G KG       P   G     +  GS  T        PPG P    PP S    G++  
Sbjct: 959  QGPKGDKGDPGVPGALGIPSGPSEGGSSSTM---YVSGPPGPPGPPGPPGSISSSGQEIQ 1015

Query: 199  AYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGS 258
             Y S    S +  +      G          PPG  G              PP  GPV +
Sbjct: 1016 QYISEYMQSDSIRSYLSGVQG----------PPGPPG--------------PP--GPVTT 1049

Query: 259  -SGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSL 317
             +G +  +  L  H     +  G  V+    S SS           V  +         L
Sbjct: 1050 ITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYL-----RQYL 1104

Query: 318  LGSRGTTA--GSSGDALGKALASIYSPDHSSN--NFSSSPSTPVG-----SPQGLAGTS 367
            +G RG     G+SGD    +L S+   + SS   ++ SS    +G      P GL GTS
Sbjct: 1105 MGPRGPPGPPGASGDG---SLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTS 1160



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 55/225 (24%), Positives = 78/225 (34%), Gaps = 25/225 (11%)

Query: 46   GGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSL---SSSTFLGPGLGGKS 102
            G S L    +S S GS   S SS     +   G+ ++ S S+    + S   G   G  +
Sbjct: 1277 GDSRLLSTDASHSRGSSSSSHSS-----SVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA 1331

Query: 103  GERGAYAS-FGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRA 161
            G+RG Y +  G   G G   + G  +G       G L  +   G   Y       S    
Sbjct: 1332 GDRGPYGTDIGPGGGYGAAAEGGMYAGN------GGLLGADFAGDLDYNELAVRVSESMQ 1385

Query: 162  ADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSL 221
              G L      V+  PPG P    PP   + +    +AY +       +   +    G  
Sbjct: 1386 RQGLLQGMAYTVQG-PPGQPGPQGPPGISKVF----SAYSNVTADLMDFFQTYGAIQGPP 1440

Query: 222  HPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFG 266
                E+ +P  +   GP    G    P PP  GP G  G     G
Sbjct: 1441 GQKGEMGTPGPKGDRGP---AGPPGHPGPP--GPRGHKGEKGDKG 1480



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 93/408 (22%), Positives = 122/408 (29%), Gaps = 46/408 (11%)

Query: 95   GPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQY----- 149
            GP   G+ GERGA    G     G     G +  + +  SPGP  P G  G         
Sbjct: 636  GPPGSGEKGERGAAGEPGPHGPPG---VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVG 692

Query: 150  YPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSST 209
             P   G        G    Q +K  +   G P     P +  + G      P+       
Sbjct: 693  LPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAG------ 746

Query: 210  YPAPFYVADGSLHPSAE--------LWSPPGQAG--FGPMLGGGSSPLPLPPGSGPVGSS 259
                    DG   P  E        +  PPG +G    P L G   P  LP   G  G  
Sbjct: 747  -------PDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIK 799

Query: 260  GSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLG 319
            G     G +   E  G  +       G P A      PGA      +  P   G   +L 
Sbjct: 800  GEPGAPGKIVTSE--GSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLP---GHQEVLN 854

Query: 320  SRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALS 379
             +G   G  G   G    SI  P             P G P      S+   +G PG   
Sbjct: 855  LQG-PPGPPGPR-GPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPG 912

Query: 380  PSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRH 439
            P    G  G         ++ +    +    + G ++   P       G  G     G  
Sbjct: 913  PPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFG-LNLQGPPGPPGPQGPKGDKGDPGVP 971

Query: 440  AGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGR 487
              L   S P +G + ST  +      P  PG       PP S S  G+
Sbjct: 972  GALGIPSGPSEGGSSSTMYVSGPPGPPGPPG-------PPGSISSSGQ 1012



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 79/316 (25%), Positives = 107/316 (33%), Gaps = 48/316 (15%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTS-QYYPSYS 154
            PG  G SG+ G+  S    A +     +   S  +++  PGP  P G+ GTS +   S  
Sbjct: 1111 PGPPGASGD-GSLLSLDY-AELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLL 1168

Query: 155  GSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGED-----YGRDATAYPSAKTPSST 209
              S  R   G            PPG+P +V+   S ED     +    +  P    P   
Sbjct: 1169 RGSEFRGIVGPPGPPG------PPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGP 1222

Query: 210  YPAP-----------FYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPG-SGPVG 257
             P P            Y A+ S    +EL S          + G       PPG  GP G
Sbjct: 1223 -PGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG-------PPGPPGPQG 1274

Query: 258  SSGSSSTFGGLHQHER-MGYQLHGAEVNGGLPSASSFSS--------APGATYGGVSSHT 308
              G S        H R      H + V  G   +SS S+          G  +G  +   
Sbjct: 1275 PPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDR 1334

Query: 309  PPVSGADSLLGSRGTTA-GSSGDALGKALASIYSPDHSSNNFSSSPSTPV---GSPQGLA 364
             P        G  G  A G      G  L + ++ D   N  +   S  +   G  QG+A
Sbjct: 1335 GPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMA 1394

Query: 365  GTSQWPRAGAPGALSP 380
             T Q P  G PG   P
Sbjct: 1395 YTVQGP-PGQPGPQGP 1409


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 99/371 (26%), Positives = 127/371 (34%), Gaps = 56/371 (15%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTS--QYYPSY 153
            PG  G  G  G     GRD   G   + G     L    PGP    G +G    +  P +
Sbjct: 1142 PGFPGSPGPMGIRGDQGRDGIPGPAGEKGETG--LLRAPPGPRGNPGAQGAKGDRGAPGF 1199

Query: 154  SGSSRRRAADGSLDTQPKKVRKV-----PPGLPSSVYPPSSGE---DYGRDATAYPSAKT 205
             G   R+ A G  D  P+    +     PPGLP ++ P  +G       R +   P    
Sbjct: 1200 PGLPGRKGAMG--DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257

Query: 206  PSSTYPAPFYVADGSL-HPSAELWSPPGQAG-FGP--MLGGGSSP-LPLPPGS------- 253
            P  ++        GS+ HP  +   PPG AG  GP   LG   +P LP P G        
Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPK--GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFP 1315

Query: 254  GPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSG 313
            G  G  G+    G +     +G +  G     G P      S PG      S   P   G
Sbjct: 1316 GVKGEKGNPGFLGSIGPPGPIGPK--GPPGVRGDPGTLKIISLPG------SPGPPGTPG 1367

Query: 314  ADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAG 373
               + G  G   G  G+ LG                   P TP   P G  G       G
Sbjct: 1368 EPGMQGEPG-PPGPPGN-LGPC------GPRGKPGKDGKPGTP--GPAGEKGNK-----G 1412

Query: 374  APGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLP----GHGALASGF 429
            + G   P+   GL GL+ K  D    A    R   V T     T +P    G   L SGF
Sbjct: 1413 SKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF-VFTRHSQTTAIPSCPEGTVPLYSGF 1471

Query: 430  TGPMSLGGRHA 440
            +     G + A
Sbjct: 1472 SFLFVQGNQRA 1482



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 51/178 (28%), Positives = 66/178 (37%), Gaps = 19/178 (10%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSY-- 153
           PGL GK G+ G     G +   G     G +  +      G + P G +G ++YY +Y  
Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQE 352

Query: 154 SGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
            G        G    +  +    PPG+P S   P S     R A  +P  K        P
Sbjct: 353 KGDEGTPGPPGPRGARGPQGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRP 409

Query: 214 FYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPG-----SGPVGSSGSSSTFG 266
              A G+  P +     PG AG  P L G   P P PPG      GP G  G     G
Sbjct: 410 GKDAMGT--PGS-----PGCAG-SPGLPGSPGP-PGPPGDIVFRKGPPGDHGLPGYLG 458



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 61/241 (25%), Positives = 81/241 (33%), Gaps = 23/241 (9%)

Query: 96   PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
            PG  G +G+ G     G+   +G     G L       +PG     G+ G     P   G
Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK----PGPHG 1119

Query: 156  SSRRRAADGSLDTQPKKVRKVP--PGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAP 213
                +   G L   P  +R  P  PG P S  P     D GRD    P+ +   +     
Sbjct: 1120 DLGFKGIKGLLG--PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET----- 1172

Query: 214  FYVADGSLH-PSAELWSPPGQAGFGPMLGGGSSPLPLPPGS-GPVGSSGSSSTFGGLHQH 271
                 G L  P     +P  Q   G     G   LP   G+ G  G  G +   G     
Sbjct: 1173 -----GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPP 1227

Query: 272  ERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTA--GSSG 329
               G  + G   N G P +     APG   G   SH   + G    +G  G     G++G
Sbjct: 1228 GLPGAIIPGQTGNRGPPGSRGSPGAPGPP-GPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 330  D 330
            D
Sbjct: 1287 D 1287



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 84/336 (25%), Positives = 109/336 (32%), Gaps = 29/336 (8%)

Query: 62  GDQSSSSFD--PSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGG 119
           G Q    F   P  T S+G          S S    PGL G  G  G Y   G     G 
Sbjct: 73  GPQGPKGFPGLPGLTGSKGVRGISGLPGFSGS----PGLPGTPGNTGPYGLVGVPGCSGS 128

Query: 120 LTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQP-KKVRKVPP 178
             + GF      L  PG    +G+KG                 D  L   P  +    PP
Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPP 188

Query: 179 GLPSSVYPPSSGEDYGRDATAYPSAKTPSST--YPAPFYVADGSLHPSAELWSPPGQAGF 236
           G P  V PP     +G     +P A  P     +     +          L  PPG  G 
Sbjct: 189 GFPGPVGPPGPPGFFG-----FPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243

Query: 237 GPM-LGGGSSPLPLPPGSGPVGSSGSSSTFG--GLHQHERMGYQLHGAEVNGGL---PSA 290
             + L G  +   L    G  G+ G     G  GL   E  G +  GA  + GL   P  
Sbjct: 244 VIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL-PGESYGSE-KGAPGDPGLQGKPGK 301

Query: 291 SSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFS 350
                 PG+     +   P + G D + G +G   G  G          Y      +  +
Sbjct: 302 DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG-DIGPPGFRGPTEYYDTY--QEKGDEGT 358

Query: 351 SSPSTPVGS--PQGLAGTSQWPRAGAPGALSPSYDG 384
             P  P G+  PQG +G    P  G+PG+  P   G
Sbjct: 359 PGPPGPRGARGPQGPSGPPGVP--GSPGSSRPGLRG 392



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 103/399 (25%), Positives = 123/399 (30%), Gaps = 93/399 (23%)

Query: 96  PGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSG 155
           PGL G  G  G     GR    G       L G     SPG    +G+ G    +P + G
Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAG-------LKG-----SPGSPGNTGLPG----FPGFPG 529

Query: 156 SSRRRAADGSLDT--QPKKVRKVP--PGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYP 211
           +       G      QP+    VP  PGL     P   G D G   T  P  K      P
Sbjct: 530 AQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQ--PGRKGLD-GIPGT--PGVKG----LP 580

Query: 212 APFYVADGSLHPSAELWS--PPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLH 269
            P     G L  S E     PPG  G  P   G + P   PPG GP G  G   T     
Sbjct: 581 GP----KGELALSGEKGDQGPPGDPG-SPGSPGPAGPAG-PPGYGPQGEPGLQGT----- 629

Query: 270 QHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSG 329
                           G+P A       G    G  S + PV G     G  G       
Sbjct: 630 ---------------QGVPGAPGPPGEAGPR--GELSVSTPVPGPPGPPGPPGHPGPQGP 672

Query: 330 DALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGL 389
             +  +L     P              +  P G  G    P  G PG   P  D G  G 
Sbjct: 673 PGIPGSLGKCGDPG-------------LPGPDGEPGI---PGIGFPGPPGPKGDQGFPGT 716

Query: 390 QSKI--EDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHA--GLVG- 444
           +  +     + E     +    G  G+    +PG G    GF G     G H   GL G 
Sbjct: 717 KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 445 ----GSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPP 479
               G+   +GL G           P QPG  P    PP
Sbjct: 776 PGLPGTPGNEGLDGP-------RGDPGQPGP-PGEQGPP 806


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.129    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,085,535
Number of Sequences: 37866
Number of extensions: 1850976
Number of successful extensions: 14428
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 144
Number of HSP's successfully gapped in prelim test: 822
Number of HSP's that attempted gapping in prelim test: 10299
Number of HSP's gapped (non-prelim): 3386
length of query: 651
length of database: 18,247,518
effective HSP length: 109
effective length of query: 542
effective length of database: 14,120,124
effective search space: 7653107208
effective search space used: 7653107208
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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