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Search of human proteins with 19743848
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19743848 decorin isoform b precursor [Homo sapiens]
(250 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19743848 decorin isoform b precursor [Homo sapiens] 510 e-145
gi|19743850 decorin isoform c precursor [Homo sapiens] 418 e-117
gi|19743846 decorin isoform a preproprotein [Homo sapiens] 365 e-101
gi|4503271 decorin isoform a preproprotein [Homo sapiens] 365 e-101
gi|19743852 decorin isoform d precursor [Homo sapiens] 254 5e-68
gi|4502403 biglycan preproprotein [Homo sapiens] 217 7e-57
gi|41350214 asporin [Homo sapiens] 212 3e-55
gi|19743854 decorin isoform e precursor [Homo sapiens] 150 1e-36
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 77 1e-14
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 77 1e-14
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 77 1e-14
gi|4505047 lumican precursor [Homo sapiens] 74 9e-14
gi|45505137 podocan [Homo sapiens] 74 9e-14
gi|188528675 slit homolog 1 [Homo sapiens] 73 3e-13
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 72 3e-13
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 72 3e-13
gi|71040111 fibromodulin precursor [Homo sapiens] 72 5e-13
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 70 1e-12
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 70 1e-12
gi|41349454 proline arginine-rich end leucine-rich repeat protei... 70 2e-12
gi|4506041 proline arginine-rich end leucine-rich repeat protein... 70 2e-12
gi|109150416 peroxidasin [Homo sapiens] 69 5e-12
gi|11321571 slit homolog 3 [Homo sapiens] 69 5e-12
gi|5901992 keratocan [Homo sapiens] 67 2e-11
gi|51317373 netrin-G1 ligand [Homo sapiens] 66 3e-11
gi|4759146 slit homolog 2 [Homo sapiens] 64 1e-10
gi|62912472 leucine-rich repeat-containing G protein-coupled rec... 64 1e-10
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 64 1e-10
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 64 2e-10
gi|4826876 osteomodulin [Homo sapiens] 63 2e-10
>gi|19743848 decorin isoform b precursor [Homo sapiens]
Length = 250
Score = 510 bits (1314), Expect = e-145
Identities = 250/250 (100%), Positives = 250/250 (100%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLD 120
HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLD
Sbjct: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLD 120
Query: 121 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA
Sbjct: 121 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
Query: 181 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 240
EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV
Sbjct: 181 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 240
Query: 241 RSAIQLGNYK 250
RSAIQLGNYK
Sbjct: 241 RSAIQLGNYK 250
>gi|19743850 decorin isoform c precursor [Homo sapiens]
Length = 212
Score = 418 bits (1074), Expect = e-117
Identities = 212/250 (84%), Positives = 212/250 (84%), Gaps = 38/250 (15%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLD 120
HLRVVQCSDL GLPPSLTELHLD
Sbjct: 61 HLRVVQCSDL--------------------------------------GLPPSLTELHLD 82
Query: 121 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA
Sbjct: 83 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 142
Query: 181 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 240
EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV
Sbjct: 143 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 202
Query: 241 RSAIQLGNYK 250
RSAIQLGNYK
Sbjct: 203 RSAIQLGNYK 212
>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 365 bits (938), Expect = e-101
Identities = 180/181 (99%), Positives = 181/181 (100%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
+ELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA
Sbjct: 179 IELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 238
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 189
ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY
Sbjct: 239 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 298
Query: 190 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 249
LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY
Sbjct: 299 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 358
Query: 250 K 250
K
Sbjct: 359 K 359
>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 365 bits (938), Expect = e-101
Identities = 180/181 (99%), Positives = 181/181 (100%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
+ELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA
Sbjct: 179 IELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 238
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 189
ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY
Sbjct: 239 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 298
Query: 190 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 249
LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY
Sbjct: 299 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 358
Query: 250 K 250
K
Sbjct: 359 K 359
>gi|19743852 decorin isoform d precursor [Homo sapiens]
Length = 172
Score = 254 bits (649), Expect = 5e-68
Identities = 141/250 (56%), Positives = 148/250 (59%), Gaps = 78/250 (31%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLD 120
HLRVVQCSDL + +P+ LPP T L L
Sbjct: 61 HLRVVQCSDL-------------------------------GLDKVPKDLPPDTTLLDLQ 89
Query: 121 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
NKI+ + K L NL + L N+IS V
Sbjct: 90 NNKITEIKDGDFKNLKNLHVVYLHNNNISVV----------------------------- 120
Query: 181 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 240
GSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV
Sbjct: 121 ------------------GSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 162
Query: 241 RSAIQLGNYK 250
RSAIQLGNYK
Sbjct: 163 RSAIQLGNYK 172
>gi|4502403 biglycan preproprotein [Homo sapiens]
Length = 368
Score = 217 bits (553), Expect = 7e-57
Identities = 107/189 (56%), Positives = 138/189 (73%), Gaps = 3/189 (1%)
Query: 62 LRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDG 121
LR + C +E+G NPL++SG E GAF G+K L+Y+RI++ +T IP+ LP +L ELHLD
Sbjct: 182 LRNMNC--IEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDH 238
Query: 122 NKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAE 181
NKI ++ L + L +LGL N I ++NGSL+ P LRELHLDNNKL RVP GL +
Sbjct: 239 NKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPD 298
Query: 182 HKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVR 241
K +QVVYLH+NNI+ VG +DFCP G K+A Y+G+SLF+NPV YWE+QP+TFRCV R
Sbjct: 299 LKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDR 358
Query: 242 SAIQLGNYK 250
AIQ GNYK
Sbjct: 359 LAIQFGNYK 367
Score = 89.4 bits (220), Expect = 3e-18
Identities = 71/238 (29%), Positives = 104/238 (43%), Gaps = 48/238 (20%)
Query: 7 LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57
L+ L +S A PF+QRG +DF L+D EASG V D P+ +CPF
Sbjct: 7 LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66
Query: 58 CQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTEL 117
C CHLRVVQCSDL G+K S+P+ + P T L
Sbjct: 67 CHCHLRVVQCSDL------------------GLK-------------SVPKEISPDTTLL 95
Query: 118 HLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG 177
L N IS + KGL +L L L N IS + + + L++L++ N L +P
Sbjct: 96 DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPP 155
Query: 178 GLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTF 235
L + + +H+N I V P G + + + + + NP++ +P F
Sbjct: 156 NLPSS--LVELRIHDNRIRKV------PKGVFSGLRNMNCIEMGGNPLENSGFEPGAF 205
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 212 bits (539), Expect = 3e-55
Identities = 98/180 (54%), Positives = 137/180 (76%), Gaps = 1/180 (0%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
LE+ NPL ++GIE GAF+G+ + +IRIA+ +TS+P+GLPP+L ELHLD NKIS V+
Sbjct: 200 LEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVEL 258
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 189
K L +LGL N I+ ++NGSLAN P +RE+HL+NNKL ++P GL E KY+Q+++
Sbjct: 259 EDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELKYLQIIF 318
Query: 190 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 249
LH+N+I+ VG +DFCP KK+ YS +SLF+NPV+YWE+QP+TFRCV R ++QLGN+
Sbjct: 319 LHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQPATFRCVLSRMSVQLGNF 378
Score = 75.1 bits (183), Expect = 5e-14
Identities = 72/262 (27%), Positives = 103/262 (39%), Gaps = 62/262 (23%)
Query: 1 MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ 45
MK ++LL LA S A PF L + ML+D + DD D
Sbjct: 1 MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPT 59
Query: 46 -------FEPSLGPVCPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRI 98
F L P+CPF CQC+ RVV CSDL L
Sbjct: 60 REPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGL-------------------------- 93
Query: 99 ADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 158
TS+P +P L L NKI + KGL +L L L+ N ++ + +
Sbjct: 94 -----TSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLT 148
Query: 159 TPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV 218
T LR L+L +N+L+ +P L K + + +H N + + F G N +
Sbjct: 149 TKKLRRLYLSHNQLSEIPLNLP--KSLAELRIHENKVKKIQKDTF--KGMNALHV----L 200
Query: 219 SLFSNPVQYWEIQPSTFRCVYV 240
+ +NP+ I+P F V V
Sbjct: 201 EMSANPLDNNGIEPGAFEGVTV 222
>gi|19743854 decorin isoform e precursor [Homo sapiens]
Length = 75
Score = 150 bits (378), Expect = 1e-36
Identities = 70/70 (100%), Positives = 70/70 (100%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDL 70
HLRVVQCSDL
Sbjct: 61 HLRVVQCSDL 70
>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
Length = 421
Score = 77.4 bits (189), Expect = 1e-14
Identities = 51/157 (32%), Positives = 80/157 (50%), Gaps = 5/157 (3%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 122
R Q +L L N L SG++ F + L Y+ ++ +T++P GLP +L LHL N
Sbjct: 147 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRN 206
Query: 123 KISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
+I +V+AA L G L L L N + S + G+L L LHL N L RVP L
Sbjct: 207 RIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP 266
Query: 181 EHKYIQVVYLHNNNISVVGSSDF-CPPGHNTKKASYS 216
+ ++ + L +N+++ +G+ D PG +Y+
Sbjct: 267 --RRLRALVLPHNHVAALGARDLVATPGLTELNLAYN 301
Score = 52.8 bits (125), Expect = 3e-07
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L L N L SSG+ GA + ++ L + + + +P LP L L L N ++ + A
Sbjct: 225 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 284
Query: 130 ASLKGLNNLAKLGLSFNSISA--VDNGSLANTPHLRELHLDNNKLTRVPGGL 179
L L +L L++N +++ V + + LR L L N+LTR+P GL
Sbjct: 285 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGL 336
Score = 52.0 bits (123), Expect = 5e-07
Identities = 27/87 (31%), Positives = 47/87 (54%)
Query: 68 SDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRV 127
++L L N L S+ + + AF+ ++ L + +A +T +P GLP L L L N++ +
Sbjct: 294 TELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRML 353
Query: 128 DAASLKGLNNLAKLGLSFNSISAVDNG 154
+ L GL+ L +L L+ N + D G
Sbjct: 354 EPEPLAGLDQLRELSLAHNRLRVGDIG 380
Score = 42.0 bits (97), Expect = 5e-04
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 27/133 (20%)
Query: 54 CPFRCQC-HLRVVQCSDLELGTNP-----------LKSSGIENGAFQGMKKLSYIRIADT 101
CP RC C + V C L+L P L+++ ++ + + +LS +R +
Sbjct: 44 CPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNL 103
Query: 102 NITSIP-QGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTP 160
+ I +GLP E SL L +L N IS V G+L+
Sbjct: 104 HNNLISSEGLPDEAFE--------------SLTQLQHLCVAHNKNNLISKVPRGALSRQT 149
Query: 161 HLRELHLDNNKLT 173
LREL+L +N+LT
Sbjct: 150 QLRELYLQHNQLT 162
>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
Length = 510
Score = 77.4 bits (189), Expect = 1e-14
Identities = 51/157 (32%), Positives = 80/157 (50%), Gaps = 5/157 (3%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 122
R Q +L L N L SG++ F + L Y+ ++ +T++P GLP +L LHL N
Sbjct: 236 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRN 295
Query: 123 KISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
+I +V+AA L G L L L N + S + G+L L LHL N L RVP L
Sbjct: 296 RIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP 355
Query: 181 EHKYIQVVYLHNNNISVVGSSDF-CPPGHNTKKASYS 216
+ ++ + L +N+++ +G+ D PG +Y+
Sbjct: 356 --RRLRALVLPHNHVAALGARDLVATPGLTELNLAYN 390
Score = 68.6 bits (166), Expect = 5e-12
Identities = 41/129 (31%), Positives = 69/129 (53%), Gaps = 4/129 (3%)
Query: 72 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 131
L N L ++G+ AF+G + ++ + +++ ++ +P LPPSL LHL N IS+V +
Sbjct: 174 LHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGA 233
Query: 132 LKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 189
L L +L L N + S +D + + L L L +N+LT VP GL + + +++
Sbjct: 234 LSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLP--RTLAILH 291
Query: 190 LHNNNISVV 198
L N I V
Sbjct: 292 LGRNRIRQV 300
Score = 57.0 bits (136), Expect = 2e-08
Identities = 42/154 (27%), Positives = 74/154 (48%), Gaps = 24/154 (15%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRV-- 127
L L N + S G+ + AF+ + +L ++ +A ++ PQ LP SL L N++ +
Sbjct: 101 LNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFP 160
Query: 128 ----DAASLKGL----NNLAKLGL---SFNSISAVDNGSLANT----------PHLRELH 166
+ +L+ + N L+ GL +F A+ SL+N P L LH
Sbjct: 161 LTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLH 220
Query: 167 LDNNKLTRVP-GGLAEHKYIQVVYLHNNNISVVG 199
L NN +++VP G L+ ++ +YL +N ++ G
Sbjct: 221 LQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 254
Score = 52.8 bits (125), Expect = 3e-07
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L L N L SSG+ GA + ++ L + + + +P LP L L L N ++ + A
Sbjct: 314 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 373
Query: 130 ASLKGLNNLAKLGLSFNSISA--VDNGSLANTPHLRELHLDNNKLTRVPGGL 179
L L +L L++N +++ V + + LR L L N+LTR+P GL
Sbjct: 374 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGL 425
Score = 52.0 bits (123), Expect = 5e-07
Identities = 27/87 (31%), Positives = 47/87 (54%)
Query: 68 SDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRV 127
++L L N L S+ + + AF+ ++ L + +A +T +P GLP L L L N++ +
Sbjct: 383 TELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRML 442
Query: 128 DAASLKGLNNLAKLGLSFNSISAVDNG 154
+ L GL+ L +L L+ N + D G
Sbjct: 443 EPEPLAGLDQLRELSLAHNRLRVGDIG 469
>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
Length = 512
Score = 77.4 bits (189), Expect = 1e-14
Identities = 51/157 (32%), Positives = 80/157 (50%), Gaps = 5/157 (3%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 122
R Q +L L N L SG++ F + L Y+ ++ +T++P GLP +L LHL N
Sbjct: 238 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRN 297
Query: 123 KISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
+I +V+AA L G L L L N + S + G+L L LHL N L RVP L
Sbjct: 298 RIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP 357
Query: 181 EHKYIQVVYLHNNNISVVGSSDF-CPPGHNTKKASYS 216
+ ++ + L +N+++ +G+ D PG +Y+
Sbjct: 358 --RRLRALVLPHNHVAALGARDLVATPGLTELNLAYN 392
Score = 68.6 bits (166), Expect = 5e-12
Identities = 41/129 (31%), Positives = 69/129 (53%), Gaps = 4/129 (3%)
Query: 72 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 131
L N L ++G+ AF+G + ++ + +++ ++ +P LPPSL LHL N IS+V +
Sbjct: 176 LHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGA 235
Query: 132 LKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 189
L L +L L N + S +D + + L L L +N+LT VP GL + + +++
Sbjct: 236 LSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLP--RTLAILH 293
Query: 190 LHNNNISVV 198
L N I V
Sbjct: 294 LGRNRIRQV 302
Score = 57.0 bits (136), Expect = 2e-08
Identities = 42/154 (27%), Positives = 74/154 (48%), Gaps = 24/154 (15%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRV-- 127
L L N + S G+ + AF+ + +L ++ +A ++ PQ LP SL L N++ +
Sbjct: 103 LNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFP 162
Query: 128 ----DAASLKGL----NNLAKLGL---SFNSISAVDNGSLANT----------PHLRELH 166
+ +L+ + N L+ GL +F A+ SL+N P L LH
Sbjct: 163 LTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLH 222
Query: 167 LDNNKLTRVP-GGLAEHKYIQVVYLHNNNISVVG 199
L NN +++VP G L+ ++ +YL +N ++ G
Sbjct: 223 LQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 256
Score = 52.8 bits (125), Expect = 3e-07
Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L L N L SSG+ GA + ++ L + + + +P LP L L L N ++ + A
Sbjct: 316 LLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGA 375
Query: 130 ASLKGLNNLAKLGLSFNSISA--VDNGSLANTPHLRELHLDNNKLTRVPGGL 179
L L +L L++N +++ V + + LR L L N+LTR+P GL
Sbjct: 376 RDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGL 427
Score = 52.0 bits (123), Expect = 5e-07
Identities = 27/87 (31%), Positives = 47/87 (54%)
Query: 68 SDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRV 127
++L L N L S+ + + AF+ ++ L + +A +T +P GLP L L L N++ +
Sbjct: 385 TELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRML 444
Query: 128 DAASLKGLNNLAKLGLSFNSISAVDNG 154
+ L GL+ L +L L+ N + D G
Sbjct: 445 EPEPLAGLDQLRELSLAHNRLRVGDIG 471
>gi|4505047 lumican precursor [Homo sapiens]
Length = 338
Score = 74.3 bits (181), Expect = 9e-14
Identities = 53/184 (28%), Positives = 84/184 (45%), Gaps = 5/184 (2%)
Query: 64 VVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNK 123
+V + + L N LK + + AF+G+K L Y+ ++ I +P GLP SL L+LD NK
Sbjct: 158 LVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNK 216
Query: 124 ISRVDAASLKGLNNLAKLGLSFNSIS-AVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH 182
IS + K N L L LS N ++ + G+ N L EL L NKL +P +
Sbjct: 217 ISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIP---TVN 273
Query: 183 KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRS 242
+ ++ YL N + FC + + L N + + P + C+ V +
Sbjct: 274 ENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVAN 333
Query: 243 AIQL 246
+ L
Sbjct: 334 EVTL 337
Score = 55.8 bits (133), Expect = 3e-08
Identities = 50/181 (27%), Positives = 83/181 (45%), Gaps = 32/181 (17%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVD- 128
L L N L++S I+ F +K+L + I N+T LP SL +L L NKI+++
Sbjct: 95 LILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGS 154
Query: 129 ----------------------AASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELH 166
+A+ KGL +L L LSFN I+ + +G + L L+
Sbjct: 155 FEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVS---LLTLY 211
Query: 167 LDNNKLTRVPGG-LAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPV 225
LDNNK++ +P +Q + L +N ++ G PG++ +S + L N +
Sbjct: 212 LDNNKISNIPDEYFKRFNALQYLRLSHNELADSGI-----PGNSFNVSSLVELDLSYNKL 266
Query: 226 Q 226
+
Sbjct: 267 K 267
Score = 42.7 bits (99), Expect = 3e-04
Identities = 28/103 (27%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 100 DTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLA 157
+ + S+P +PP + L+L N+I +D + + + +L L L N + S + +
Sbjct: 55 ELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFS 113
Query: 158 NTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGS 200
L++LH+++N LT G L K ++ + L +N I+ +GS
Sbjct: 114 KLKQLKKLHINHNNLTESVGPLP--KSLEDLQLTHNKITKLGS 154
>gi|45505137 podocan [Homo sapiens]
Length = 661
Score = 74.3 bits (181), Expect = 9e-14
Identities = 47/137 (34%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Query: 69 DLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVD 128
+L L N L G++N F + L Y+ ++ N++ +P GLP SL LHL+ N I VD
Sbjct: 314 ELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVD 373
Query: 129 AASLKGLNNLAKLGLSFNSISAVDNGSLA--NTPHLRELHLDNNKLTRVPGGLAEHKYIQ 186
A L + +L L L N + LA L +HL NN L RVP GL + ++
Sbjct: 374 ANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLP--RRVR 431
Query: 187 VVYLHNNNISVVGSSDF 203
+ + +N I+ +G DF
Sbjct: 432 TLMILHNQITGIGREDF 448
Score = 65.1 bits (157), Expect = 6e-11
Identities = 45/167 (26%), Positives = 81/167 (48%), Gaps = 10/167 (5%)
Query: 72 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 131
L N L +G+ + F G + + ++ + +P+ LPP+L +LHL NK+ ++ +
Sbjct: 246 LHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGA 305
Query: 132 LKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 189
L++L +L L N ++ +DN + L L L +N L+RVP GL + + +++
Sbjct: 306 FSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLP--RSLVLLH 363
Query: 190 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFR 236
L N I V ++ P S + L SN ++ I P F+
Sbjct: 364 LEKNAIRSVDANVLTP------IRSLEYLLLHSNQLREQGIHPLAFQ 404
Score = 63.2 bits (152), Expect = 2e-10
Identities = 45/170 (26%), Positives = 84/170 (49%), Gaps = 10/170 (5%)
Query: 69 DLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVD 128
+L L N + S + AF+ ++ L + ++ + ++P GLP ++ L + N+++ +
Sbjct: 456 ELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALA 515
Query: 129 AASLKGLNNLAKLGLSFNSISAVDNGSLA--NTPHLRELHLDNNKLTRVPGGLAEHKYIQ 186
+L G+ L +L L+ N + + G A + HL+ L + N+LT +P GL E ++
Sbjct: 516 RGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPES--LE 573
Query: 187 VVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFR 236
+YL NN IS V ++ F + G+ L N + + S FR
Sbjct: 574 YLYLQNNKISAVPANAF------DSTPNLKGIFLRFNKLAVGSVVDSAFR 617
Score = 58.5 bits (140), Expect = 5e-09
Identities = 36/109 (33%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Query: 64 VVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNK 123
+ Q +L L +N L+S + A+ + L + IA +T IP+GLP SL L+L NK
Sbjct: 522 MAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNK 581
Query: 124 ISRVDAASLKGLNNLAKLGLSFN--SISAVDNGSLANTPHLRELHLDNN 170
IS V A + NL + L FN ++ +V + + HL+ L ++ N
Sbjct: 582 ISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630
Score = 57.4 bits (137), Expect = 1e-08
Identities = 46/161 (28%), Positives = 78/161 (48%), Gaps = 24/161 (14%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 122
R+ + L L N L S G+ AF+ + L+Y+ +A+ +T P+ LP +L + N
Sbjct: 166 RLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAAN 225
Query: 123 KISRV------DAASLKGL----NNLAKLGL---SFNSISAVDNGSLANT---------- 159
++++ +L+ + N LA GL FN S V+ L++
Sbjct: 226 YLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLP 285
Query: 160 PHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNNNISVVG 199
P L +LHL NNKL ++ PG +E ++ +YL NN ++ G
Sbjct: 286 PALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEG 326
Score = 55.1 bits (131), Expect = 6e-08
Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L L +N L+ GI AFQG+K+L + + + + +P GLP + L + N+I+ +
Sbjct: 386 LLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGR 445
Query: 130 ASLKGLNNLAKLGLSFNSISA--VDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYI 185
L +L LS+N I++ V + LR L L N+L +P GL + ++
Sbjct: 446 EDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHV 503
Score = 38.9 bits (89), Expect = 0.004
Identities = 46/205 (22%), Positives = 69/205 (33%), Gaps = 66/205 (32%)
Query: 26 DFMLEDEASGIGPEVPDDRDFEPSLGPV---CPFRCQCHLR-VVQCSDLELGTNPLKSSG 81
+F E+ + PE EP GP CP C C VV C ++L
Sbjct: 92 EFAEEEPVLVLSPE-------EPGPGPAAVSCPRDCACSQEGVVDCGGIDL--------- 135
Query: 82 IENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKL 141
P LP L L N++ ++ L L+ L L
Sbjct: 136 ----------------------REFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETL 173
Query: 142 GLSFNSISA--VDNGSLANTPHLRELHLDNNKLTRVPGGL-------------------- 179
L N +++ + + + +L L+L NNKLT P L
Sbjct: 174 NLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGL 233
Query: 180 --AEHKYIQVVYLHNNNISVVGSSD 202
+ ++ VYLHNN ++ G D
Sbjct: 234 TFGQKPNLRSVYLHNNKLADAGLPD 258
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 72.8 bits (177), Expect = 3e-13
Identities = 54/196 (27%), Positives = 87/196 (44%), Gaps = 41/196 (20%)
Query: 53 VCPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPP 112
VCP +C+C VV+CS L+L T IP+ +P
Sbjct: 512 VCPHKCRCEANVVECSSLKL-------------------------------TKIPERIPQ 540
Query: 113 SLTELHLDGNKISRVDAASL-KGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 171
S EL L+ N+IS ++A + K L +L K+ LS N +S +++G+ + ELHL N+
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 172 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEI 230
L + G+ ++ + L NN IS + + F T + +SL+ N Q +
Sbjct: 601 LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSF------TGLRNVRLLSLYDN--QITTV 652
Query: 231 QPSTFRCVYVRSAIQL 246
P F + S + L
Sbjct: 653 SPGAFDTLQSLSTLNL 668
Score = 56.6 bits (135), Expect = 2e-08
Identities = 38/131 (29%), Positives = 68/131 (51%), Gaps = 8/131 (6%)
Query: 96 IRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 155
+R ++ ++ ++P+G+P ++TEL+LDGN+ + V L L + LS N IS++ N S
Sbjct: 745 VRCSNKHLRALPKGIPKNVTELYLDGNQFTLV-PGQLSTFKYLQLVDLSNNKISSLSNSS 803
Query: 156 LANTPHLRELHLDNNKLTRVPG-GLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKAS 214
N L L L N L +P + ++++ LH N+IS + F S
Sbjct: 804 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIF------ADVTS 857
Query: 215 YSGVSLFSNPV 225
S +++ +NP+
Sbjct: 858 LSHLAIGANPL 868
Score = 56.2 bits (134), Expect = 3e-08
Identities = 41/168 (24%), Positives = 77/168 (45%), Gaps = 18/168 (10%)
Query: 54 CPFRCQCHLRVVQC---------SDLELGTNPLKSSG-----IENGAFQGMKKLSYIRIA 99
CP C C V C ++ T L+ +G I F G+K+L +++
Sbjct: 34 CPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLM 93
Query: 100 DTNITSIPQGLPPSLTELH---LDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSL 156
+ I ++ +G + EL L+ N++ + + L++L LS N+I A+ +
Sbjct: 94 ENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAF 153
Query: 157 ANTPHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNNNISVVGSSDF 203
L+ L LD N+++ + G + ++V+ L+NNNI+ + S F
Sbjct: 154 RGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Score = 49.3 bits (116), Expect = 3e-06
Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 7/125 (5%)
Query: 103 ITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHL 162
+T+IP LP ++TE+ L+ N I + + L ++ LS N I+ + + L
Sbjct: 300 LTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSL 359
Query: 163 RELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLF 221
L L NK+T +P G+ Y +Q++ L+ N I+ + F + S +SL+
Sbjct: 360 NSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF------QDLQNLSLLSLY 413
Query: 222 SNPVQ 226
N +Q
Sbjct: 414 DNKIQ 418
Score = 45.4 bits (106), Expect = 5e-05
Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 5/104 (4%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHL---DGNKISR 126
++L N + I AFQG++ L+ + + IT +P+G+ L L L + NKI+
Sbjct: 338 IDLSNNQIAE--IAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINC 395
Query: 127 VDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNN 170
+ + + L NL+ L L N I ++ G+ + ++ LHL N
Sbjct: 396 IRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 44.7 bits (104), Expect = 8e-05
Identities = 36/138 (26%), Positives = 58/138 (42%), Gaps = 34/138 (24%)
Query: 62 LRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIP-------------- 107
LRV+Q + ++G +E GAF MK+L +R+ + +P
Sbjct: 87 LRVLQLMENQIGA-------VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLD 139
Query: 108 ------QGLP-------PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 154
Q +P L L LD N+IS ++ + + L L L L+ N+I+ +
Sbjct: 140 LSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVS 199
Query: 155 SLANTPHLRELHLDNNKL 172
S + P LR L +N L
Sbjct: 200 SFNHMPKLRTFRLHSNHL 217
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 72.4 bits (176), Expect = 3e-13
Identities = 48/131 (36%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L+L N + SSGI AF+ +KKL + + N+ IP LP +L EL ++ N + +D
Sbjct: 372 LDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDE 431
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNGSLANTP--HLRELHLDNNKLTRVPGGLAEHKYIQV 187
SL LN L L L N++S + LA P L L L NK +P GL I+
Sbjct: 432 ESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGS--IEE 489
Query: 188 VYLHNNNISVV 198
+YL NN I +
Sbjct: 490 LYLENNQIEEI 500
Score = 64.3 bits (155), Expect = 9e-11
Identities = 56/193 (29%), Positives = 89/193 (46%), Gaps = 7/193 (3%)
Query: 58 CQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTEL 117
C H R + + L N ++ + I A+ + L I ++ + +P LP SL L
Sbjct: 504 CFNHTRKINV--IVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHL 561
Query: 118 HLDGNKISRVDAASLKGLN-NLAKLGLSFNSIS--AVDNGSLANTPH-LRELHLDNNKLT 173
L GN+I R+ + L L LSFN ++ +D S H LREL LD+N L
Sbjct: 562 VLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLK 621
Query: 174 RVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPS 233
+P G+ E K + + L+NN I + + C ++ + L +N ++ EI
Sbjct: 622 SIPPGIQEMKALHFLRLNNNKIRNILPEEIC-NAEEDDDSNLEHLHLENNYIKIREIPSY 680
Query: 234 TFRCVYVRSAIQL 246
TF C+ S+I L
Sbjct: 681 TFSCIRSYSSIVL 693
Score = 60.5 bits (145), Expect = 1e-09
Identities = 41/129 (31%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Query: 66 QCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKIS 125
Q LEL N L + + AF+ +K L+Y+R+ IPQGLP S+ EL+L+ N+I
Sbjct: 439 QLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIE 498
Query: 126 RVDAASLKGLNNLAKLGLSFNSISAVDNGSLA--NTPHLRELHLDNNKLTRVPGGLAEHK 183
+ + + L +N I LA N +L + L NKL VP L +
Sbjct: 499 EITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPK-S 557
Query: 184 YIQVVYLHN 192
+ +V L N
Sbjct: 558 LLHLVLLGN 566
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/110 (31%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
Query: 93 LSYIRIADTN--ITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISA 150
LSY I+ N +T IP P +T L L GN I+ + + GL NL +L LS N+I++
Sbjct: 322 LSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITS 381
Query: 151 VDNGSLA--NTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVV 198
G A L L++D N L ++P L ++ + ++ NN+ +
Sbjct: 382 SGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLP--STLEELKVNENNLQAI 429
>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
sapiens]
Length = 674
Score = 72.4 bits (176), Expect = 3e-13
Identities = 46/136 (33%), Positives = 73/136 (53%), Gaps = 3/136 (2%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 122
R+ L L N + + IE AF K+L + ++ +++SIP GLP +L EL LD N
Sbjct: 149 RIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDN 208
Query: 123 KISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
+IS + + KGLN+L +L L N ++ + + + + +L EL L N L P L
Sbjct: 209 RISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLP 268
Query: 181 EHKYIQVVYLHNNNIS 196
++Q +YL +N IS
Sbjct: 269 S-AHLQKLYLQDNAIS 283
Score = 61.2 bits (147), Expect = 8e-10
Identities = 47/162 (29%), Positives = 78/162 (48%), Gaps = 19/162 (11%)
Query: 54 CPFRCQCHLRVVQCSDLELGTNP-----------LKSSGIEN-GAFQGMK---KLSYIRI 98
CP C+C + C+D L + P L+++ I N G Q +K + I +
Sbjct: 54 CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYL 113
Query: 99 ADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSL 156
+ ++ P LP SL ELHL N + + SL + L KL L NS+S +++ +
Sbjct: 114 YENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAF 173
Query: 157 ANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVV 198
A++ L+ L L N L+ +P GL ++ + L +N IS +
Sbjct: 174 ADSKQLKLLFLSRNHLSSIPSGLPH--TLEELRLDDNRISTI 213
>gi|71040111 fibromodulin precursor [Homo sapiens]
Length = 376
Score = 72.0 bits (175), Expect = 5e-13
Identities = 48/134 (35%), Positives = 68/134 (50%), Gaps = 3/134 (2%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
+ L N + S + F ++ L + + N+T +P LP SL ELHLD N+ISRV
Sbjct: 134 IALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPN 193
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 189
+L+GL NL L L N I V S+ L L L N L +VP GL ++ +Y
Sbjct: 194 NALEGLENLTALYLQHNEIQEV-GSSMRGLRSLILLDLSYNHLRKVPDGLP--SALEQLY 250
Query: 190 LHNNNISVVGSSDF 203
+ +NN+ V S F
Sbjct: 251 MEHNNVYTVPDSYF 264
Score = 55.5 bits (132), Expect = 4e-08
Identities = 34/122 (27%), Positives = 65/122 (53%), Gaps = 8/122 (6%)
Query: 86 AFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSF 145
+ +G++ L + ++ ++ +P GLP +L +L+++ N + V + +G L + LS
Sbjct: 218 SMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSH 277
Query: 146 NSISAVDNGSLANT---PHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSD 202
NS++ +NG +NT L EL L N+L ++P + ++ +YL N I+ S
Sbjct: 278 NSLT--NNGLASNTFNSSSLLELDLSYNQLQKIP---PVNTNLENLYLQGNRINEFSISS 332
Query: 203 FC 204
FC
Sbjct: 333 FC 334
Score = 32.7 bits (73), Expect = 0.30
Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 18/105 (17%)
Query: 82 IENGAFQGMKKLSYIRIADTNITSIPQGL------PPSLTELHLDGNKISRVDAASLKGL 135
+ + F+G KL Y+R++ ++T+ GL SL EL L N++ ++ +
Sbjct: 259 VPDSYFRGAPKLLYVRLSHNSLTN--NGLASNTFNSSSLLELDLSYNQLQKIPPVN---- 312
Query: 136 NNLAKLGLSFNSISAVDNGS------LANTPHLRELHLDNNKLTR 174
NL L L N I+ S + N L+ L LD N++ R
Sbjct: 313 TNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKR 357
>gi|38202222 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 70.5 bits (171), Expect = 1e-12
Identities = 45/143 (31%), Positives = 78/143 (54%), Gaps = 3/143 (2%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 122
++ +L L N + + IE GAF+ L + ++ ++++IP GLP ++ EL LD N
Sbjct: 126 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDN 185
Query: 123 KISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
+IS + + SL+GL +L +L L N ++ + + N +L EL L N LT P L
Sbjct: 186 RISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLP 245
Query: 181 EHKYIQVVYLHNNNISVVGSSDF 203
++ +YL +N+I+ V + F
Sbjct: 246 GTN-LRKLYLQDNHINRVPPNAF 267
Score = 66.2 bits (160), Expect = 2e-11
Identities = 48/165 (29%), Positives = 78/165 (47%), Gaps = 21/165 (12%)
Query: 54 CPFRCQCHLRVVQCSD----------------LELGTNPLKSSGIENGAFQGMKKLSYIR 97
CP C+C + C+D L L N + ++GI + + + K+ I
Sbjct: 31 CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSD-LKNLLKVERIY 89
Query: 98 IADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV--DNGS 155
+ ++ P LP + ELHL N I + SL + L +L L NS+SAV + G+
Sbjct: 90 LYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGA 149
Query: 156 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGS 200
++ +LR L L N L+ +P GL + I+ + L +N IS + S
Sbjct: 150 FRDSNYLRLLFLSRNHLSTIPWGLP--RTIEELRLDDNRISTISS 192
>gi|7019383 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 70.5 bits (171), Expect = 1e-12
Identities = 45/143 (31%), Positives = 78/143 (54%), Gaps = 3/143 (2%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 122
++ +L L N + + IE GAF+ L + ++ ++++IP GLP ++ EL LD N
Sbjct: 126 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDN 185
Query: 123 KISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
+IS + + SL+GL +L +L L N ++ + + N +L EL L N LT P L
Sbjct: 186 RISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLP 245
Query: 181 EHKYIQVVYLHNNNISVVGSSDF 203
++ +YL +N+I+ V + F
Sbjct: 246 GTN-LRKLYLQDNHINRVPPNAF 267
Score = 66.2 bits (160), Expect = 2e-11
Identities = 48/165 (29%), Positives = 78/165 (47%), Gaps = 21/165 (12%)
Query: 54 CPFRCQCHLRVVQCSD----------------LELGTNPLKSSGIENGAFQGMKKLSYIR 97
CP C+C + C+D L L N + ++GI + + + K+ I
Sbjct: 31 CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSD-LKNLLKVERIY 89
Query: 98 IADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV--DNGS 155
+ ++ P LP + ELHL N I + SL + L +L L NS+SAV + G+
Sbjct: 90 LYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGA 149
Query: 156 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGS 200
++ +LR L L N L+ +P GL + I+ + L +N IS + S
Sbjct: 150 FRDSNYLRLLFLSRNHLSTIPWGLP--RTIEELRLDDNRISTISS 192
>gi|41349454 proline arginine-rich end leucine-rich repeat protein
precursor [Homo sapiens]
Length = 382
Score = 69.7 bits (169), Expect = 2e-12
Identities = 41/139 (29%), Positives = 73/139 (52%), Gaps = 8/139 (5%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L+L N L + F G+K L + +A + +P +P ++ +L+LD NKI +
Sbjct: 200 LDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPN 259
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNG---SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQ 186
K NLA + L++N ++ D G + N +L LHL +N+++ VP A + ++
Sbjct: 260 GYFKSFPNLAFIRLNYNKLT--DRGLPKNSFNISNLLVLHLSHNRISSVP---AINNRLE 314
Query: 187 VVYLHNNNISVVGSSDFCP 205
+YL+NN+I + + CP
Sbjct: 315 HLYLNNNSIEKINGTQICP 333
Score = 47.0 bits (110), Expect = 2e-05
Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 9/134 (6%)
Query: 102 NITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPH 161
N+ +P +PP + L+L N I+ + S + L + L N I +D L P
Sbjct: 93 NLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPG 151
Query: 162 LRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLF 221
L L+++ N+L VP L + ++ + L N+IS + PPG +K + + L
Sbjct: 152 LVFLYMEKNQLEEVPSALPRN--LEQLRLSQNHISRI------PPGVFSKLENLLLLDLQ 203
Query: 222 SNPVQYWEIQPSTF 235
N + +P TF
Sbjct: 204 HNRLSDGVFKPDTF 217
Score = 46.2 bits (108), Expect = 3e-05
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 29/124 (23%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPS------LTELHLDGNK 123
L L +N +++ I NG F+ L++IR+ +T +GLP + L LHL N+
Sbjct: 247 LYLDSNKIET--IPNGYFKSFPNLAFIRLNYNKLTD--RGLPKNSFNISNLLVLHLSHNR 302
Query: 124 ISRVDAASLKGLNNLAKLGLSFNSISAVD---------------NGSLANTPHLRELHLD 168
IS V A + N L L L+ NSI ++ + L N PHLR L LD
Sbjct: 303 ISSVPAIN----NRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLD 358
Query: 169 NNKL 172
N L
Sbjct: 359 GNYL 362
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/124 (25%), Positives = 55/124 (44%), Gaps = 4/124 (3%)
Query: 82 IENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKL 141
I+ + + L ++ + + +P LP +L +L L N ISR+ L NL L
Sbjct: 141 IDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLL 200
Query: 142 GLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVG 199
L N +S + +L +L+L +N L ++P + I +YL +N I +
Sbjct: 201 DLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVP--TAIHQLYLDSNKIETIP 258
Query: 200 SSDF 203
+ F
Sbjct: 259 NGYF 262
>gi|4506041 proline arginine-rich end leucine-rich repeat protein
precursor [Homo sapiens]
Length = 382
Score = 69.7 bits (169), Expect = 2e-12
Identities = 41/139 (29%), Positives = 73/139 (52%), Gaps = 8/139 (5%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L+L N L + F G+K L + +A + +P +P ++ +L+LD NKI +
Sbjct: 200 LDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPN 259
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNG---SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQ 186
K NLA + L++N ++ D G + N +L LHL +N+++ VP A + ++
Sbjct: 260 GYFKSFPNLAFIRLNYNKLT--DRGLPKNSFNISNLLVLHLSHNRISSVP---AINNRLE 314
Query: 187 VVYLHNNNISVVGSSDFCP 205
+YL+NN+I + + CP
Sbjct: 315 HLYLNNNSIEKINGTQICP 333
Score = 47.0 bits (110), Expect = 2e-05
Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 9/134 (6%)
Query: 102 NITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPH 161
N+ +P +PP + L+L N I+ + S + L + L N I +D L P
Sbjct: 93 NLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPG 151
Query: 162 LRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLF 221
L L+++ N+L VP L + ++ + L N+IS + PPG +K + + L
Sbjct: 152 LVFLYMEKNQLEEVPSALPRN--LEQLRLSQNHISRI------PPGVFSKLENLLLLDLQ 203
Query: 222 SNPVQYWEIQPSTF 235
N + +P TF
Sbjct: 204 HNRLSDGVFKPDTF 217
Score = 46.2 bits (108), Expect = 3e-05
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 29/124 (23%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPS------LTELHLDGNK 123
L L +N +++ I NG F+ L++IR+ +T +GLP + L LHL N+
Sbjct: 247 LYLDSNKIET--IPNGYFKSFPNLAFIRLNYNKLTD--RGLPKNSFNISNLLVLHLSHNR 302
Query: 124 ISRVDAASLKGLNNLAKLGLSFNSISAVD---------------NGSLANTPHLRELHLD 168
IS V A + N L L L+ NSI ++ + L N PHLR L LD
Sbjct: 303 ISSVPAIN----NRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLD 358
Query: 169 NNKL 172
N L
Sbjct: 359 GNYL 362
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/124 (25%), Positives = 55/124 (44%), Gaps = 4/124 (3%)
Query: 82 IENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKL 141
I+ + + L ++ + + +P LP +L +L L N ISR+ L NL L
Sbjct: 141 IDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLL 200
Query: 142 GLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVG 199
L N +S + +L +L+L +N L ++P + I +YL +N I +
Sbjct: 201 DLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVP--TAIHQLYLDSNKIETIP 258
Query: 200 SSDF 203
+ F
Sbjct: 259 NGYF 262
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 68.6 bits (166), Expect = 5e-12
Identities = 46/148 (31%), Positives = 67/148 (45%), Gaps = 16/148 (10%)
Query: 51 GPVCPFRCQCHLRVVQCSDLELGTNPL-------------KSSGIENGAFQGMKKLSYIR 97
G CP RC C V+C L L P + I+ GAF+ ++ L+ +
Sbjct: 33 GAGCPSRCLCFRTTVRCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLL 92
Query: 98 IADTNITSIPQGLPPSLTEL---HLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 154
+ + I IP G L L +L N+I +D + KGL +L +L L FN I +D
Sbjct: 93 LNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPD 152
Query: 155 SLANTPHLRELHLDNNKLTRVPGGLAEH 182
S + P L L L NN++T + G H
Sbjct: 153 SFQHLPKLERLFLHNNRITHLVPGTFNH 180
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 68.6 bits (166), Expect = 5e-12
Identities = 54/180 (30%), Positives = 83/180 (46%), Gaps = 45/180 (25%)
Query: 50 LGPVCPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQG 109
L P CP +C C VV+CS+ + ++P+G
Sbjct: 721 LSPRCPEQCTCMETVVRCSN-------------------------------KGLRALPRG 749
Query: 110 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 169
+P +TEL+L+GN ++ V L L +L + LS NSIS + N + +N HL L L
Sbjct: 750 MPKDVTELYLEGNHLTAV-PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSY 808
Query: 170 NKLTRVP----GGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPV 225
N+L +P GL + ++V+ LH N+IS V P G S S ++L +NP+
Sbjct: 809 NRLRCIPVHAFNGL---RSLRVLTLHGNDISSV------PEGSFNDLTSLSHLALGTNPL 859
Score = 60.5 bits (145), Expect = 1e-09
Identities = 41/139 (29%), Positives = 72/139 (51%), Gaps = 11/139 (7%)
Query: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGL---PPSLTEL 117
+LRV+ D ++ S IE GAFQ +K+L +R+ + +P+ L P LT L
Sbjct: 86 NLRVLHLEDNQV-------SVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRL 138
Query: 118 HLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG 177
L N+I + + +G+ ++ L L N IS +++G+ L L L+NN ++R+
Sbjct: 139 DLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILV 198
Query: 178 GLAEH-KYIQVVYLHNNNI 195
H I+ + LH+N++
Sbjct: 199 TSFNHMPKIRTLRLHSNHL 217
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/160 (27%), Positives = 72/160 (45%), Gaps = 19/160 (11%)
Query: 53 VCPFRCQCHLRVVQCSD--------------LELGTNPLKSSGIE-NGAFQGMKKLSYIR 97
VCP +C+C +V CS+ +L N + S +E G F+ + L I
Sbjct: 504 VCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKIN 563
Query: 98 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 154
+++ I + +G S+ EL L GN++ V +GL+ L L L N I V N
Sbjct: 564 LSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSND 623
Query: 155 SLANTPHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNN 193
+ A +R L L +N++T + PG + + L +N
Sbjct: 624 TFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 55.8 bits (133), Expect = 3e-08
Identities = 52/161 (32%), Positives = 73/161 (45%), Gaps = 24/161 (14%)
Query: 54 CPFRCQCHLRVVQCS----------------DLELGTNPLKSSGIENGAFQGMKKLSYIR 97
CP C C +V C ++ L N +K+ I GAF KKL I
Sbjct: 280 CPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKA--IPAGAFTQYKKLKRID 337
Query: 98 IADTNITSIP----QGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDN 153
I+ I+ I QGL SLT L L GNKI+ + GL +L L L+ N I+ +
Sbjct: 338 ISKNQISDIAPDAFQGLK-SLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRV 396
Query: 154 GSLANTPHLRELHLDNNKLTRVPGGL-AEHKYIQVVYLHNN 193
+ + +L L L +NKL + GL A + IQ ++L N
Sbjct: 397 NTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Score = 53.5 bits (127), Expect = 2e-07
Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 31/123 (25%)
Query: 54 CPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPS 113
CP +C C V C L L ++P+G+P +
Sbjct: 34 CPTKCTCSAASVDCHGLGL-------------------------------RAVPRGIPRN 62
Query: 114 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT 173
L LD N I+R+ GL NL L L N +S ++ G+ + L L L+ NKL
Sbjct: 63 AERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQ 122
Query: 174 RVP 176
+P
Sbjct: 123 VLP 125
Score = 43.9 bits (102), Expect = 1e-04
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 103 ITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHL 162
+ IP LP + E+ L+ N I + A + L ++ +S N IS + + L
Sbjct: 298 LMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSL 357
Query: 163 RELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNISVVGSSDF 203
L L NK+T + GL + +Q++ L+ N I+ + + F
Sbjct: 358 TSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTF 399
>gi|5901992 keratocan [Homo sapiens]
Length = 352
Score = 66.6 bits (161), Expect = 2e-11
Identities = 45/154 (29%), Positives = 72/154 (46%), Gaps = 9/154 (5%)
Query: 52 PVCPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP 111
P PF LR + L N + + GIE GA +KKL ++ + D + +P LP
Sbjct: 87 PEKPFENATQLRWIN-----LNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLP 141
Query: 112 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDN 169
SL +L L NK+SR+ + L NL L L N + +A + +L +L++
Sbjct: 142 RSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAK 201
Query: 170 NKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 203
N L +P L + ++L NN+I + + F
Sbjct: 202 NALRNMPPRLPAN--TMQLFLDNNSIEGIPENYF 233
Score = 57.8 bits (138), Expect = 9e-09
Identities = 40/139 (28%), Positives = 69/139 (49%), Gaps = 8/139 (5%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L+L N L + + F+G+K L + +A + ++P LP + +L LD N I +
Sbjct: 171 LDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPE 230
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNGSLA---NTPHLRELHLDNNKLTRVPGGLAEHKYIQ 186
+ +A L L+ N +S D G + + + +L L +N+LT+VP A ++Q
Sbjct: 231 NYFNVIPKVAFLRLNHNKLS--DEGLPSRGFDVSSILDLQLSHNQLTKVPRISA---HLQ 285
Query: 187 VVYLHNNNISVVGSSDFCP 205
++L +N I V S CP
Sbjct: 286 HLHLDHNKIKSVNVSVICP 304
Score = 38.5 bits (88), Expect = 0.006
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 12/103 (11%)
Query: 70 LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129
L L N L G+ + F + + ++++ +T +P+ + L LHLD NKI V+
Sbjct: 242 LRLNHNKLSDEGLPSRGFD-VSSILDLQLSHNQLTKVPR-ISAHLQHLHLDHNKIKSVNV 299
Query: 130 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 172
+ + S+ + S + PHLR L LD N++
Sbjct: 300 SVI----------CPSPSMLPAERDSFSYGPHLRYLRLDGNEI 332
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 65.9 bits (159), Expect = 3e-11
Identities = 43/133 (32%), Positives = 70/133 (52%), Gaps = 3/133 (2%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPP-SLTELHLDG 121
R+ L+LG + S I GAF+G+ L Y+ +A N+ IP P L EL L G
Sbjct: 170 RIPSLRRLDLGELK-RLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSG 228
Query: 122 NKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL-A 180
N +S + S +GL +L KL + + I ++ + N L E++L +N LT +P L
Sbjct: 229 NHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFT 288
Query: 181 EHKYIQVVYLHNN 193
+++ ++LH+N
Sbjct: 289 PLHHLERIHLHHN 301
Score = 49.7 bits (117), Expect = 2e-06
Identities = 31/103 (30%), Positives = 52/103 (50%), Gaps = 1/103 (0%)
Query: 102 NITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPH 161
N+ +P G+ + L+L N+I + S K L +L L LS N I ++ G+ +
Sbjct: 66 NLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLAN 125
Query: 162 LRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 203
L L L +N+LT +P G + ++ ++L NN I + S F
Sbjct: 126 LNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAF 168
Score = 47.4 bits (111), Expect = 1e-05
Identities = 40/147 (27%), Positives = 69/147 (46%), Gaps = 9/147 (6%)
Query: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQG---LPPSLTEL 117
HLR ++ L+L N +++ IE GAF G+ L+ + + D +T+IP G L EL
Sbjct: 98 HLRHLEI--LQLSRNHIRT--IEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKEL 153
Query: 118 HLDGNKISRVDAASLKGLNNLAKLGL-SFNSISAVDNGSLANTPHLRELHLDNNKLTRVP 176
L N I + + + + +L +L L +S + G+ +LR L+L L +P
Sbjct: 154 WLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIP 213
Query: 177 GGLAEHKYIQVVYLHNNNISVVGSSDF 203
L + + L N++S + F
Sbjct: 214 -NLTPLIKLDELDLSGNHLSAIRPGSF 239
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 63.9 bits (154), Expect = 1e-10
Identities = 55/187 (29%), Positives = 87/187 (46%), Gaps = 41/187 (21%)
Query: 42 DDRDFEPSLGPV--CPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIA 99
DD + + S P+ CP C C VV+CS+ +G+K L
Sbjct: 713 DDGNDDNSCSPLSRCPTECTCLDTVVRCSN------------------KGLKVL------ 748
Query: 100 DTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 159
P+G+P +TEL+LDGN+ + V L +L + LS N IS + N S +N
Sbjct: 749 -------PKGIPRDVTELYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNM 800
Query: 160 PHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV 218
L L L N+L +P + K ++++ LH N+ISVV P G ++ S +
Sbjct: 801 TQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVV------PEGAFNDLSALSHL 854
Query: 219 SLFSNPV 225
++ +NP+
Sbjct: 855 AIGANPL 861
Score = 62.4 bits (150), Expect = 4e-10
Identities = 41/139 (29%), Positives = 70/139 (50%), Gaps = 11/139 (7%)
Query: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGL---PPSLTEL 117
HLRV+Q + ++ T IE GAFQ +K+L +R+ ++ P+ L L L
Sbjct: 80 HLRVLQLMENKIST-------IERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRL 132
Query: 118 HLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG 177
L N+I + + +G ++ L L +N IS +++G+ L L L+NN +TR+
Sbjct: 133 DLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSV 192
Query: 178 GLAEH-KYIQVVYLHNNNI 195
H ++ LH+NN+
Sbjct: 193 ASFNHMPKLRTFRLHSNNL 211
Score = 50.8 bits (120), Expect = 1e-06
Identities = 48/161 (29%), Positives = 74/161 (45%), Gaps = 24/161 (14%)
Query: 54 CPFRCQCHLRVVQC----------------SDLELGTNPLKSSGIENGAFQGMKKLSYIR 97
CP C C +V C +++ L N +K I GAF KKL I
Sbjct: 273 CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKV--IPPGAFSPYKKLRRID 330
Query: 98 IADTNITSIP----QGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDN 153
+++ I+ + QGL SL L L GNKI+ + + +GL +L L L+ N I+ +
Sbjct: 331 LSNNQISELAPDAFQGLR-SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRV 389
Query: 154 GSLANTPHLRELHLDNNKL-TRVPGGLAEHKYIQVVYLHNN 193
+ + +L L L +NKL T G + + IQ ++L N
Sbjct: 390 DAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 49.3 bits (116), Expect = 3e-06
Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 31/123 (25%)
Query: 54 CPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPS 113
CP +C C V C L L S+P+ +P +
Sbjct: 28 CPAQCSCSGSTVDCHGLAL-------------------------------RSVPRNIPRN 56
Query: 114 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT 173
L L+GN I+R+ GL +L L L N IS ++ G+ + L L L+ N L
Sbjct: 57 TERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQ 116
Query: 174 RVP 176
P
Sbjct: 117 LFP 119
Score = 48.1 bits (113), Expect = 7e-06
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 103 ITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHL 162
+T IP LP ++TE+ L+ N I + + L ++ LS N IS + + L
Sbjct: 291 LTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSL 350
Query: 163 RELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNIS 196
L L NK+T +P L E + +Q++ L+ N I+
Sbjct: 351 NSLVLYGNKITELPKSLFEGLFSLQLLLLNANKIN 385
Score = 45.8 bits (107), Expect = 3e-05
Identities = 44/195 (22%), Positives = 84/195 (43%), Gaps = 25/195 (12%)
Query: 40 VPDDRDFEPSLGP------VCPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKL 93
+P D+ L CP +C+C V CS+ +L P + +L
Sbjct: 486 IPGTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHIP-----QYTAELRL 540
Query: 94 SYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDN 153
+ T I + LP L +++ NKI+ ++ + +G + + ++ L+ N + V +
Sbjct: 541 NNNEFTVLEATGIFKKLP-QLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQH 599
Query: 154 GSLANTPHLRELHLDNNKLTRVPG----GLAEHKYIQVVYLHNNNISVVGSSDFCPPGHN 209
L+ L L +N++T V GL+ ++++ L++N I+ V PG
Sbjct: 600 KMFKGLESLKTLMLRSNRITCVGNDSFIGLSS---VRLLSLYDNQITTVA------PGAF 650
Query: 210 TKKASYSGVSLFSNP 224
S S ++L +NP
Sbjct: 651 DTLHSLSTLNLLANP 665
>gi|62912472 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 2 [Homo sapiens]
Length = 915
Score = 63.9 bits (154), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 8/147 (5%)
Query: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP---PSLTEL 117
HLR ++ +L L N L S I AF G+ L + + + + IP PSL L
Sbjct: 36 HLRFLE--ELRLSGNHL--SHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSL 91
Query: 118 HLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG 177
LD N IS V S +GL++L L L N+++ + +L N P L+ + L N+++ +P
Sbjct: 92 RLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPD 151
Query: 178 GLAEH-KYIQVVYLHNNNISVVGSSDF 203
++ + V++LHNN I +G+ F
Sbjct: 152 YAFQNLTSLVVLHLHNNRIQHLGTHSF 178
Score = 50.8 bits (120), Expect = 1e-06
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 86 AFQGMKKLSYIRIADTNITSIPQGLP---PSLTELHLDGNKISRVDAASLKGLNNLAKLG 142
+F+G+ L ++ + D +T IP P+L + L N+IS + + + L +L L
Sbjct: 105 SFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLH 164
Query: 143 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSD 202
L N I + S +L L L+ NKL P + +Q + HNNNI +
Sbjct: 165 LHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKA 224
Query: 203 FCPPGHNTKKASYSGVSLFSNPVQY 227
F + + NP+Q+
Sbjct: 225 F------MGNPLLQTIHFYDNPIQF 243
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 13/172 (7%)
Query: 71 ELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELH---LDGNKISRV 127
ELG + I AF G L I D I + + L +LH L+G +
Sbjct: 209 ELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG-AMDIQ 267
Query: 128 DAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQV 187
+ LKG +L L L+ I + +G P LR L L +N++ +P L + ++
Sbjct: 268 EFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKLEE 326
Query: 188 VYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVY 239
+ L +N I +G+ F ++ +S + L N ++ I P F ++
Sbjct: 327 IGLQHNRIWEIGADTF------SQLSSLQALDLSWNAIR--SIHPEAFSTLH 370
Score = 40.0 bits (92), Expect = 0.002
Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 5/107 (4%)
Query: 82 IENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKGLNNLAK 140
+ +G Q + +L + ++ I +P L E+ L N+I + A + L++L
Sbjct: 291 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQA 350
Query: 141 LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVP----GGLAEHK 183
L LS+N+I ++ + + L +L L +N+LT +P GGL K
Sbjct: 351 LDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397
Score = 30.8 bits (68), Expect = 1.2
Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 143 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNI 195
LS N+++ + G + L EL L N L+ +PG Y ++++ L NN +
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQL 74
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 63.9 bits (154), Expect = 1e-10
Identities = 47/147 (31%), Positives = 76/147 (51%), Gaps = 8/147 (5%)
Query: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP---PSLTEL 117
HLR ++ +L L N L S I AF G+ L + + + + IP PSL L
Sbjct: 88 HLRFLE--ELRLSGNHL--SHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSL 143
Query: 118 HLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG 177
LD N IS V S +GL++L L L N+++ + +L N P L+ + L N+++ +P
Sbjct: 144 RLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPD 203
Query: 178 GLAEH-KYIQVVYLHNNNISVVGSSDF 203
++ + V++LHNN I +G+ F
Sbjct: 204 YAFQNLTSLVVLHLHNNRIQHLGTHSF 230
Score = 50.8 bits (120), Expect = 1e-06
Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 9/145 (6%)
Query: 86 AFQGMKKLSYIRIADTNITSIPQGLP---PSLTELHLDGNKISRVDAASLKGLNNLAKLG 142
+F+G+ L ++ + D +T IP P+L + L N+IS + + + L +L L
Sbjct: 157 SFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLH 216
Query: 143 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSD 202
L N I + S +L L L+ NKL P + +Q + HNNNI +
Sbjct: 217 LHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKA 276
Query: 203 FCPPGHNTKKASYSGVSLFSNPVQY 227
F + + NP+Q+
Sbjct: 277 F------MGNPLLQTIHFYDNPIQF 295
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 13/172 (7%)
Query: 71 ELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELH---LDGNKISRV 127
ELG + I AF G L I D I + + L +LH L+G +
Sbjct: 261 ELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG-AMDIQ 319
Query: 128 DAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQV 187
+ LKG +L L L+ I + +G P LR L L +N++ +P L + ++
Sbjct: 320 EFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKLEE 378
Query: 188 VYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVY 239
+ L +N I +G+ F ++ +S + L N ++ I P F ++
Sbjct: 379 IGLQHNRIWEIGADTF------SQLSSLQALDLSWNAIR--SIHPEAFSTLH 422
Score = 40.0 bits (92), Expect = 0.002
Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 5/107 (4%)
Query: 82 IENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKGLNNLAK 140
+ +G Q + +L + ++ I +P L E+ L N+I + A + L++L
Sbjct: 343 LPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQA 402
Query: 141 LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVP----GGLAEHK 183
L LS+N+I ++ + + L +L L +N+LT +P GGL K
Sbjct: 403 LDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 449
Score = 32.7 bits (73), Expect = 0.30
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 139 AKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNI 195
A L LS N+++ + G + L EL L N L+ +PG Y ++++ L NN +
Sbjct: 69 AYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQL 126
>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
sapiens]
Length = 660
Score = 63.5 bits (153), Expect = 2e-10
Identities = 37/143 (25%), Positives = 78/143 (54%), Gaps = 3/143 (2%)
Query: 63 RVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 122
++++ +L L N + + G+E+GAF+ L + ++ +++S+P GLP L EL +D N
Sbjct: 131 QLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDEN 190
Query: 123 KISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
+I+ + + + L +L +L + N ++ + G+ ++ L+E + N L+ P L
Sbjct: 191 RIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLP 250
Query: 181 EHKYIQVVYLHNNNISVVGSSDF 203
I+ +YL +N I+ + + F
Sbjct: 251 GTHLIR-LYLQDNQINHIPLTAF 272
Score = 59.7 bits (143), Expect = 2e-09
Identities = 46/167 (27%), Positives = 73/167 (43%), Gaps = 19/167 (11%)
Query: 54 CPFRCQCHLRVVQCSDLELGTNPL-----------KSSGIENGAF----QGMKKLSYIRI 98
CP C+C V C++ L + PL ++ I N F ++ + + +
Sbjct: 36 CPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYL 95
Query: 99 ADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSL 156
+ P LP ++ LHL N I + A+L L L +L L NSIS V++G+
Sbjct: 96 YGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAF 155
Query: 157 ANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 203
L+ L L N L+ VP GL +Q + + N I+V+ F
Sbjct: 156 REAISLKLLFLSKNHLSSVPVGLPVD--LQELRVDENRIAVISDMAF 200
>gi|4826876 osteomodulin [Homo sapiens]
Length = 421
Score = 63.2 bits (152), Expect = 2e-10
Identities = 42/144 (29%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
Query: 62 LRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDG 121
+ ++ L N +KS I+ G F + L + + N+ P LP SL L L
Sbjct: 112 INATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGY 171
Query: 122 NKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHLDNNKLTRVPGGL 179
N+IS++ ++ GL NL L L +N + S + + A L +L+L +N+L +P GL
Sbjct: 172 NEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGL 231
Query: 180 AEHKYIQVVYLHNNNISVVGSSDF 203
+ + L NN+IS + F
Sbjct: 232 PSS--LMYLSLENNSISSIPEKYF 253
Score = 61.2 bits (147), Expect = 8e-10
Identities = 45/145 (31%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Query: 64 VVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNK 123
+V + L+L N L S +++ F M+KL + + + S+P GLP SL L L+ N
Sbjct: 185 LVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNS 244
Query: 124 ISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTR---VPGGLA 180
IS + L L L +S N + + ++ N P++ EL + +NKL + +P L
Sbjct: 245 ISSIPEKYFDKLPKLHTLRMSHNKLQDIPY-NIFNLPNIVELSVGHNKLKQAFYIPRNL- 302
Query: 181 EHKYIQVVYLHNNNISVVGSSDFCP 205
EH +YL NN I + + CP
Sbjct: 303 EH-----LYLQNNEIEKMNLTVMCP 322
Score = 36.2 bits (82), Expect = 0.028
Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 10/92 (10%)
Query: 107 PQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELH 166
P P S+ + D K+ + + ++ +L L FN I AV S N HL+E++
Sbjct: 69 PTNFPSSM---YCDNRKLKTIPNIPM----HIQQLYLQFNEIEAVTANSFINATHLKEIN 121
Query: 167 LDNNKLTRVP---GGLAEHKYIQVVYLHNNNI 195
L +NK+ G A+ + ++L +NN+
Sbjct: 122 LSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNL 153
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,090,544
Number of Sequences: 37866
Number of extensions: 449458
Number of successful extensions: 2115
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 958
Number of HSP's gapped (non-prelim): 769
length of query: 250
length of database: 18,247,518
effective HSP length: 100
effective length of query: 150
effective length of database: 14,460,918
effective search space: 2169137700
effective search space used: 2169137700
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.