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Search of human proteins with 195972866
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195972866 keratin 10 [Homo sapiens]
(584 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195972866 keratin 10 [Homo sapiens] 1179 0.0
gi|55956899 keratin 9 [Homo sapiens] 601 e-172
gi|192807292 keratin 24 [Homo sapiens] 521 e-148
gi|15431310 keratin 14 [Homo sapiens] 491 e-138
gi|131412228 keratin 13 isoform b [Homo sapiens] 489 e-138
gi|131412225 keratin 13 isoform a [Homo sapiens] 489 e-138
gi|24430192 keratin 16 [Homo sapiens] 489 e-138
gi|24430190 keratin 15 [Homo sapiens] 488 e-138
gi|4557699 keratin 12 [Homo sapiens] 487 e-137
gi|114431246 keratin 25D [Homo sapiens] 468 e-132
gi|4557701 keratin 17 [Homo sapiens] 463 e-130
gi|153945736 keratin 27 [Homo sapiens] 459 e-129
gi|31559829 keratin 25 [Homo sapiens] 450 e-126
gi|24234699 keratin 19 [Homo sapiens] 434 e-122
gi|31559815 keratin 26 [Homo sapiens] 416 e-116
gi|119395750 keratin 1 [Homo sapiens] 370 e-102
gi|4504927 keratin 36 [Homo sapiens] 359 3e-99
gi|94538345 keratin 35 [Homo sapiens] 355 8e-98
gi|116488398 keratin 32 [Homo sapiens] 337 1e-92
gi|14917115 keratin 31 [Homo sapiens] 333 3e-91
gi|14917117 keratin 33A [Homo sapiens] 332 6e-91
gi|47132620 keratin 2 [Homo sapiens] 330 3e-90
gi|10337581 type I hair keratin 3B [Homo sapiens] 327 1e-89
gi|27894337 keratin 20 [Homo sapiens] 326 3e-89
gi|40354195 keratin 18 [Homo sapiens] 324 1e-88
gi|4557888 keratin 18 [Homo sapiens] 324 1e-88
gi|14917119 keratin 34 [Homo sapiens] 318 9e-87
gi|109148552 keratin 3 [Homo sapiens] 298 1e-80
gi|153791670 keratin 76 [Homo sapiens] 296 5e-80
gi|125490370 type I hair keratin KA36 [Homo sapiens] 295 1e-79
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 1179 bits (3049), Expect = 0.0
Identities = 584/584 (100%), Positives = 584/584 (100%)
Query: 1 MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRG 60
MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRG
Sbjct: 1 MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRG 60
Query: 61 SSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGG 120
SSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGG
Sbjct: 61 SSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGG 120
Query: 121 GFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKE 180
GFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKE
Sbjct: 121 GFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKE 180
Query: 181 WYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYEN 240
WYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYEN
Sbjct: 181 WYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYEN 240
Query: 241 EVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTG 300
EVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTG
Sbjct: 241 EVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTG 300
Query: 301 DVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISS 360
DVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISS
Sbjct: 301 DVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISS 360
Query: 361 YKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQ 420
YKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQ
Sbjct: 361 YKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQ 420
Query: 421 IRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGG 480
IRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGG
Sbjct: 421 IRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGG 480
Query: 481 GSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGG 540
GSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGG
Sbjct: 481 GSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGG 540
Query: 541 GYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584
GYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY
Sbjct: 541 GYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 601 bits (1549), Expect = e-172
Identities = 349/623 (56%), Positives = 408/623 (65%), Gaps = 49/623 (7%)
Query: 1 MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSL--RISSSKGSLGGG-FSSGGFSGGSF 57
MS R SS + S S GGGGGGG G GG + S R SSS G GGG FSS GG
Sbjct: 1 MSCRQFSSSYLSRS---GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGS 57
Query: 58 SR--GSSGGGCFG-----GSSGGYGGL---GGFGGGSFRGSYGSSSFGGSYGGSFGGGSF 107
SR G GGG FG GS GG+ GGFGGGS RG G+S G S G FGGG F
Sbjct: 58 SRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGS-RGFGGASGGGYSSSGGFGGG-F 115
Query: 108 GGGSFGGGSFGGG-GFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRA 166
GGGS GG FGGG G G GGFGG GG GGDGG+L+ NEK TMQ LN RLASYLDKV+A
Sbjct: 116 GGGS--GGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQA 173
Query: 167 LEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDN 226
LEE+N +LE KI++WY+K G + ++YS YY TIDDLK+QI++LT N LL IDN
Sbjct: 174 LEEANNDLENKIQDWYDKKGPA--AIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDN 231
Query: 227 ARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKN 286
R+ DDFR+K+E E LRQ V+ADINGLR+VLD LT+ K+DLEMQ E+L EEL LKKN
Sbjct: 232 TRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKN 291
Query: 287 HEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKE 346
H+EEM L ++GDVNVE+N APG DLT+ LN+MR +YEQL +NRKD E + + +
Sbjct: 292 HKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQ 351
Query: 347 LTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQ 406
+ E+ ++ +++ S E+T+LR VQ LEIELQSQL+ K +LE SL +T+ RYC QL
Sbjct: 352 IEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQM 411
Query: 407 IQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLE---------GEG 457
IQ QIS LE Q+ +R E ECQN EY LL IK+RLE EI+TY +LLE G G
Sbjct: 412 IQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAG 471
Query: 458 SSGGGGRG--GGSFGGGY---GGGSSGGGSSGGGHGGGHG--GSSGGGYGGGSSGGGSSG 510
G GGRG GGS+G G GGS GGG SGGG+GGG G G SGG YGGGS GG SG
Sbjct: 472 KIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSG 531
Query: 511 GGYGGGS-------SSGGHGGSSSGGYGG--GSSGGGGGGYGGGSSGGGSSSGGGYGGGS 561
GGYGGGS S GGH G S G YGG GS GG GGGYGGG SG SGG +GGGS
Sbjct: 532 GGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG-SGSRGGSGGSHGGGS 590
Query: 562 SSGGHKSSSSGSVGESSSKGPRY 584
GG S G E+S G Y
Sbjct: 591 GFGGESGGSYGGGEEASGSGGGY 613
Score = 124 bits (311), Expect = 2e-28
Identities = 65/112 (58%), Positives = 66/112 (58%), Gaps = 14/112 (12%)
Query: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYG 514
G G GGG GGGS GGG+ GGS GGGH G SGG YGGGS GG SGGGYG
Sbjct: 525 GSGGGSGGGYGGGS-GGGHSGGS----------GGGHSGGSGGNYGGGSGSGGGSGGGYG 573
Query: 515 GGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGH 566
GGS S G G S GG G G G GG YGGG G SGGGYGGGS H
Sbjct: 574 GGSGSRGGSGGSHGG-GSGFGGESGGSYGGGEEASG--SGGGYGGGSGKSSH 622
Score = 68.9 bits (167), Expect = 1e-11
Identities = 42/96 (43%), Positives = 46/96 (47%), Gaps = 16/96 (16%)
Query: 11 YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS 70
+S GG GG G GGG S GG S GG+ GGS SRG S GGS
Sbjct: 542 HSGGSGGGHSGGSGGNYGGGSGS-----------GGGSGGGYGGGSGSRGGS-----GGS 585
Query: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGS 106
GG G GG GGS+ G +S GG YGG G S
Sbjct: 586 HGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
Score = 35.0 bits (79), Expect = 0.19
Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 16/67 (23%)
Query: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGG 65
S + S S GG GG GG G GG S G + GG + GS GG
Sbjct: 568 SGGGYGGGSGSRGGSGGSHGGGSG--------------FGGESGGSYGGGEEASGSGGG- 612
Query: 66 CFGGSSG 72
+GG SG
Sbjct: 613 -YGGGSG 618
Score = 32.7 bits (73), Expect = 0.95
Identities = 17/30 (56%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 454 EGEGSSGGGGRGGGSFGGGYGGGSSGGGSS 483
E GS GGG GS GGGYGGGS S
Sbjct: 595 ESGGSYGGGEEASGS-GGGYGGGSGKSSHS 623
Score = 30.8 bits (68), Expect = 3.6
Identities = 18/48 (37%), Positives = 19/48 (39%)
Query: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFS 53
S S+ S GGG G GG GG S S G GGG S
Sbjct: 576 SGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 521 bits (1341), Expect = e-148
Identities = 297/503 (59%), Positives = 349/503 (69%), Gaps = 24/503 (4%)
Query: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG- 64
S S SSSR+GG GG SS S+ LGG S+ GF GG+ S SGG
Sbjct: 2 SCSSRASSSRAGGSSSARVSAGGSSFSS----GSRCGLGGS-SAQGFRGGASSCSLSGGS 56
Query: 65 -GCFGGS-SGGYGGL---GGFGG--GSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSF 117
G FGGS GG+G GGFGG GS G G SSFGG G G G G F G+
Sbjct: 57 SGAFGGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGAT 116
Query: 118 GGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGK 177
GG GGG GGG G DGGL SG EK TMQNLNDRLA+YLDKVRALEE+N +LE K
Sbjct: 117 GGFYSYGGGMGGGVG-----DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENK 171
Query: 178 IKEWYEKHG--NSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFR 235
IKEWY+K+G + G RDYSKYY I+DL+NQI+ T +NA I+L IDNARLAADDFR
Sbjct: 172 IKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFR 231
Query: 236 LKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLR 295
LKYENE+ LRQSVEADINGLR+VLD+LT+T++DLEMQIES TEELAYL+KNHEEEMK+++
Sbjct: 232 LKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQ 291
Query: 296 NVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNI 355
S G+V VEMNAAPG DLT+LLN+MR+QYE+LAEQNR++AE FN++S L +I +
Sbjct: 292 GSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDA 351
Query: 356 EQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALE 415
+S K+EITEL+R +QALEIELQSQLA+K SLE +LA+TE Y QLS+IQ QISALE
Sbjct: 352 GAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALE 411
Query: 416 EQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGG----GGRGGGSFGG 471
E++ QI ET+CQN EY+QLLDIK RLE EI+TYR LL+GEG GGR GS
Sbjct: 412 EEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNM 471
Query: 472 GYGGGSSGGGSSGGGHGGGHGGS 494
G SG SG G G S
Sbjct: 472 GSRDLVSGDSRSGSCSGQGRDSS 494
Score = 84.0 bits (206), Expect = 4e-16
Identities = 52/113 (46%), Positives = 60/113 (53%), Gaps = 11/113 (9%)
Query: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG-----SSGGG 512
SSG GGS G+ GG+S SGG G GGS GGG+G S GGG SG G
Sbjct: 28 SSGSRCGLGGSSAQGFRGGASSCSLSGGS-SGAFGGSFGGGFGSCSVGGGFGGASGSGTG 86
Query: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGG 565
+GGGSS GG G+G GS G + G++GG S GGG GGG GG
Sbjct: 87 FGGGSSFGG-----VSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGG 134
Score = 81.3 bits (199), Expect = 2e-15
Identities = 57/126 (45%), Positives = 64/126 (50%), Gaps = 9/126 (7%)
Query: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYG--G 515
S R GGS S+GG S G G GGSS G+ GG+S SGG G G
Sbjct: 5 SRASSSRAGGSSSARV---SAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFG 61
Query: 516 GSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVG 575
GS GG G S GG GG+SG G G +GGGSS GG S G+G GS G SSG+ G
Sbjct: 62 GSFGGGFGSCSVGGGFGGASGSGTG-FGGGSSFGGVS---GFGRGSGFCGSSRFSSGATG 117
Query: 576 ESSSKG 581
S G
Sbjct: 118 GFYSYG 123
Score = 78.2 bits (191), Expect = 2e-14
Identities = 55/110 (50%), Positives = 59/110 (53%), Gaps = 18/110 (16%)
Query: 457 GSSGGGGRGG-----------GSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG 505
GSS G RGG G+FGG +GGG G S GGG GG G SG G+GGGSS
Sbjct: 37 GSSAQGFRGGASSCSLSGGSSGAFGGSFGGGF-GSCSVGGGFGGASG--SGTGFGGGSSF 93
Query: 506 GGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGG 555
GG S G+G GS G SSG GG S GGG GGG GG SGG
Sbjct: 94 GGVS--GFGRGSGFCGSSRFSSGATGGFYS--YGGGMGGGVGDGGLFSGG 139
Score = 45.8 bits (107), Expect = 1e-04
Identities = 27/64 (42%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGG--GYGGGSSGGGSSGGG 512
G S G G GGGS GG G G G G G++GG YGGG GG GG
Sbjct: 78 GGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFS--SGATGGFYSYGGGMGGGVGDGGL 135
Query: 513 YGGG 516
+ GG
Sbjct: 136 FSGG 139
Score = 38.1 bits (87), Expect = 0.023
Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Query: 517 SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGG-GSSSGGGYGGGSSSGGHKSSSSGSVG 575
S S S +GG GG + GS G G SS G+ GG+SS SSG+ G
Sbjct: 2 SCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFG 61
Query: 576 ESSSKG 581
S G
Sbjct: 62 GSFGGG 67
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 491 bits (1263), Expect = e-138
Identities = 273/424 (64%), Positives = 314/424 (74%), Gaps = 17/424 (4%)
Query: 37 SSSKGSLGGGFSSGGFSGGSFSRGSS---GGGCFGGSSGGYGGLGGFGGGSFRGSYGSS- 92
SS KGS G G GG GGS SR SS GG C S+ G GG S R S G +
Sbjct: 12 SSMKGSCGIG---GGIGGGS-SRISSVLAGGSCRAPSTYG----GGLSVSSSRFSSGGAY 63
Query: 93 SFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQN 152
GG YGG F S GS GG +GGG G G GGGFGGGF G GLL G+EKVTMQN
Sbjct: 64 GLGGGYGGGFSSSSSSFGSGFGGGYGGGL--GAGLGGGFGGGFAGGDGLLVGSEKVTMQN 121
Query: 153 LNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILN 212
LNDRLASYLDKVRALEE+N +LE KI++WY++ E +DYS Y+KTI+DL+N+IL
Sbjct: 122 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQ---RPAEIKDYSPYFKTIEDLRNKILT 178
Query: 213 LTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQ 272
T DNAN+LLQIDNARLAADDFR KYE E+ LR SVEADINGLRRVLDELTL +ADLEMQ
Sbjct: 179 ATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQ 238
Query: 273 IESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQN 332
IESL EELAYLKKNHEEEM LR GDVNVEM+AAPGVDL+++LN MR QYE++AE+N
Sbjct: 239 IESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKN 298
Query: 333 RKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEAS 392
RKDAE WF K++EL E+ N E + S KSEI+ELRR +Q LEIELQSQL++K SLE S
Sbjct: 299 RKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENS 358
Query: 393 LAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSL 452
L ET+GRYC+QL+QIQ I ++EEQL Q+R E E QN EY+ LLD+K RLE EI TYR L
Sbjct: 359 LEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRL 418
Query: 453 LEGE 456
LEGE
Sbjct: 419 LEGE 422
Score = 74.3 bits (181), Expect = 3e-13
Identities = 47/102 (46%), Positives = 54/102 (52%), Gaps = 13/102 (12%)
Query: 458 SSGGGGRGGGSFGGGYGGGSS------GGGS--SGGGHGGGHGGSSGGGYGGGSSGGGSS 509
+S +G GGG GGGSS GGS + +GGG SS GG+ G
Sbjct: 9 TSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYG---L 65
Query: 510 GGGYGGG--SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGG 549
GGGYGGG SSS G GGYGGG G GGG+GGG +GG
Sbjct: 66 GGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGG 107
Score = 63.2 bits (152), Expect = 7e-10
Identities = 39/77 (50%), Positives = 42/77 (54%), Gaps = 10/77 (12%)
Query: 496 GGGYGGGSS------GGGS--SGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSS 547
GGG GGGSS GGS + YGGG S SS G YG G GG GGG+ SS
Sbjct: 21 GGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLG--GGYGGGFSSSSS 78
Query: 548 GGGSSSGGGYGGGSSSG 564
GS GGGYGGG +G
Sbjct: 79 SFGSGFGGGYGGGLGAG 95
Score = 57.8 bits (138), Expect = 3e-08
Identities = 32/60 (53%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 459 SGGGGRGGGSFGGGYGGGSSGGGSS-GGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS 517
S GG G GGGYGGG S SS G G GGG+GG G G GGG GG + G G GS
Sbjct: 58 SSGGAYG---LGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGS 114
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/42 (50%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSG 496
G G S G FGGGYGGG G GGG GGG G G
Sbjct: 70 GGGFSSSSSSFGSGFGGGYGGGL--GAGLGGGFGGGFAGGDG 109
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/82 (40%), Positives = 36/82 (43%), Gaps = 7/82 (8%)
Query: 505 GGGSSGGGYGGGSS---SGGHGGS--SSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGG 559
G GGG GGGSS S GGS + YGGG S GG+ G G GGG+
Sbjct: 16 GSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSS 75
Query: 560 GSSSGGHKSSSSGSVGESSSKG 581
SSS G S G G G
Sbjct: 76 SSSSFG--SGFGGGYGGGLGAG 95
Score = 37.4 bits (85), Expect = 0.038
Identities = 31/75 (41%), Positives = 31/75 (41%), Gaps = 18/75 (24%)
Query: 525 SSSGGYGGGSSGGGG---------GG-------YGGGSSGGGS--SSGGGYGGGSSSGGH 566
S G G G GGG GG YGGG S S SSGG YG G GG
Sbjct: 13 SMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGG 72
Query: 567 KSSSSGSVGESSSKG 581
SSSS S G G
Sbjct: 73 FSSSSSSFGSGFGGG 87
Score = 36.2 bits (82), Expect = 0.086
Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 3/44 (6%)
Query: 449 YRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHG 492
Y SS G G GGG +GGG G G GG GGG GG G
Sbjct: 69 YGGGFSSSSSSFGSGFGGG-YGGGLGAGL--GGGFGGGFAGGDG 109
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 489 bits (1259), Expect = e-138
Identities = 265/432 (61%), Positives = 314/432 (72%), Gaps = 29/432 (6%)
Query: 33 SLRISSSKGSLGGGFSSGG--FSGGSFSRGSSGGGCFGGSSGGYGG--LGGFGGGSFRGS 88
SLR+ SS S GGGF G GG S GGS+GGYGG GFGGG+
Sbjct: 2 SLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGA---- 57
Query: 89 YGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGF----GGDGGLLSG 144
S FGG YGG GGG +GGG GGGFGGGF GGF DGGLL+G
Sbjct: 58 --GSGFGGGYGGGLGGG------YGGGL-------GGGFGGGFAGGFVDFGACDGGLLTG 102
Query: 145 NEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTID 204
NEK+TMQNLNDRLASYL+KVRALEE+N +LE KI++W+ K S RDYS YYKTI+
Sbjct: 103 NEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQ--SPASPERDYSPYYKTIE 160
Query: 205 DLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTL 264
+L+++IL T +N ++L+IDNARLAADDFRLKYENE+ALRQSVEADINGLRRVLDELTL
Sbjct: 161 ELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTL 220
Query: 265 TKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQ 324
+K DLEMQIESL EELAY+KKNHEEEMK+ N G VNVEM+A PG+DLT++L MR Q
Sbjct: 221 SKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQ 280
Query: 325 YEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLA 384
YE +AE+NR+DAE WF+ KS EL E+ N I + K+EITELRR +Q LEIELQSQL+
Sbjct: 281 YEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLS 340
Query: 385 LKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLEN 444
+K LE ++AETE RY +QL QIQ IS++E QL ++R+E ECQN EY+ LLDIK RLE
Sbjct: 341 MKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQ 400
Query: 445 EIQTYRSLLEGE 456
EI TYRSLLEG+
Sbjct: 401 EIATYRSLLEGQ 412
Score = 82.4 bits (202), Expect = 1e-15
Identities = 46/105 (43%), Positives = 56/105 (53%), Gaps = 13/105 (12%)
Query: 453 LEGEGSSGGGGRGGGS--FGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510
L+ +S GGG GGGS GGG G + GG GG+GG G+GGG+ G
Sbjct: 5 LQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGA------G 58
Query: 511 GGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGG 555
G+G GG+GG GGYGGG GG GGG+ GG G+ GG
Sbjct: 59 SGFG-----GGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
Score = 77.8 bits (190), Expect = 3e-14
Identities = 40/84 (47%), Positives = 49/84 (58%), Gaps = 3/84 (3%)
Query: 482 SSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGG 541
SS +GGG GG G GG G + + G S+GG+GG S G+GGG+ G GGG
Sbjct: 7 SSSASYGGGFGG--GSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGG 64
Query: 542 YGGGSSGG-GSSSGGGYGGGSSSG 564
YGGG GG G GGG+GGG + G
Sbjct: 65 YGGGLGGGYGGGLGGGFGGGFAGG 88
Score = 70.9 bits (172), Expect = 3e-12
Identities = 40/90 (44%), Positives = 48/90 (53%), Gaps = 13/90 (14%)
Query: 438 IKIRLENEIQTYRSLLEGEGSSGGGGRG---------GGSFGGGYGGGSSGG--GSSGGG 486
+ +RL++ +Y G GGGRG G GGYGGG S G G +G G
Sbjct: 1 MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60
Query: 487 HGGGHGGSSGGGYGGGSSGGGSSGGGYGGG 516
GGG+GG GGGYGGG GG GGG+ GG
Sbjct: 61 FGGGYGGGLGGGYGGGL--GGGFGGGFAGG 88
Score = 67.0 bits (162), Expect = 5e-11
Identities = 34/64 (53%), Positives = 38/64 (59%)
Query: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGG 516
G S GG GG S G G G GS GG GGG GGG+GG GGG+GGG +GG G GG
Sbjct: 39 GGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
Query: 517 SSSG 520
+G
Sbjct: 99 LLTG 102
Score = 37.7 bits (86), Expect = 0.029
Identities = 28/61 (45%), Positives = 29/61 (47%), Gaps = 14/61 (22%)
Query: 525 SSSGGYGGGSSGGGGGGYGGGS----------SGGGSSSGGGYGGGSSSGGHKSSSSGSV 574
SSS YGGG GGG GGG SGG S GGYGGG S G + SG
Sbjct: 7 SSSASYGGGF-GGGSCQLGGGRGVSTCSTRFVSGG---SAGGYGGGVSCGFGGGAGSGFG 62
Query: 575 G 575
G
Sbjct: 63 G 63
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 489 bits (1259), Expect = e-138
Identities = 265/432 (61%), Positives = 314/432 (72%), Gaps = 29/432 (6%)
Query: 33 SLRISSSKGSLGGGFSSGG--FSGGSFSRGSSGGGCFGGSSGGYGG--LGGFGGGSFRGS 88
SLR+ SS S GGGF G GG S GGS+GGYGG GFGGG+
Sbjct: 2 SLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGA---- 57
Query: 89 YGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGF----GGDGGLLSG 144
S FGG YGG GGG +GGG GGGFGGGF GGF DGGLL+G
Sbjct: 58 --GSGFGGGYGGGLGGG------YGGGL-------GGGFGGGFAGGFVDFGACDGGLLTG 102
Query: 145 NEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTID 204
NEK+TMQNLNDRLASYL+KVRALEE+N +LE KI++W+ K S RDYS YYKTI+
Sbjct: 103 NEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQ--SPASPERDYSPYYKTIE 160
Query: 205 DLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTL 264
+L+++IL T +N ++L+IDNARLAADDFRLKYENE+ALRQSVEADINGLRRVLDELTL
Sbjct: 161 ELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTL 220
Query: 265 TKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQ 324
+K DLEMQIESL EELAY+KKNHEEEMK+ N G VNVEM+A PG+DLT++L MR Q
Sbjct: 221 SKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQ 280
Query: 325 YEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLA 384
YE +AE+NR+DAE WF+ KS EL E+ N I + K+EITELRR +Q LEIELQSQL+
Sbjct: 281 YEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLS 340
Query: 385 LKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLEN 444
+K LE ++AETE RY +QL QIQ IS++E QL ++R+E ECQN EY+ LLDIK RLE
Sbjct: 341 MKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQ 400
Query: 445 EIQTYRSLLEGE 456
EI TYRSLLEG+
Sbjct: 401 EIATYRSLLEGQ 412
Score = 82.4 bits (202), Expect = 1e-15
Identities = 46/105 (43%), Positives = 56/105 (53%), Gaps = 13/105 (12%)
Query: 453 LEGEGSSGGGGRGGGS--FGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510
L+ +S GGG GGGS GGG G + GG GG+GG G+GGG+ G
Sbjct: 5 LQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGA------G 58
Query: 511 GGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGG 555
G+G GG+GG GGYGGG GG GGG+ GG G+ GG
Sbjct: 59 SGFG-----GGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
Score = 77.8 bits (190), Expect = 3e-14
Identities = 40/84 (47%), Positives = 49/84 (58%), Gaps = 3/84 (3%)
Query: 482 SSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGG 541
SS +GGG GG G GG G + + G S+GG+GG S G+GGG+ G GGG
Sbjct: 7 SSSASYGGGFGG--GSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGG 64
Query: 542 YGGGSSGG-GSSSGGGYGGGSSSG 564
YGGG GG G GGG+GGG + G
Sbjct: 65 YGGGLGGGYGGGLGGGFGGGFAGG 88
Score = 70.9 bits (172), Expect = 3e-12
Identities = 40/90 (44%), Positives = 48/90 (53%), Gaps = 13/90 (14%)
Query: 438 IKIRLENEIQTYRSLLEGEGSSGGGGRG---------GGSFGGGYGGGSSGG--GSSGGG 486
+ +RL++ +Y G GGGRG G GGYGGG S G G +G G
Sbjct: 1 MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60
Query: 487 HGGGHGGSSGGGYGGGSSGGGSSGGGYGGG 516
GGG+GG GGGYGGG GG GGG+ GG
Sbjct: 61 FGGGYGGGLGGGYGGGL--GGGFGGGFAGG 88
Score = 67.0 bits (162), Expect = 5e-11
Identities = 34/64 (53%), Positives = 38/64 (59%)
Query: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGG 516
G S GG GG S G G G GS GG GGG GGG+GG GGG+GGG +GG G GG
Sbjct: 39 GGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
Query: 517 SSSG 520
+G
Sbjct: 99 LLTG 102
Score = 37.7 bits (86), Expect = 0.029
Identities = 28/61 (45%), Positives = 29/61 (47%), Gaps = 14/61 (22%)
Query: 525 SSSGGYGGGSSGGGGGGYGGGS----------SGGGSSSGGGYGGGSSSGGHKSSSSGSV 574
SSS YGGG GGG GGG SGG S GGYGGG S G + SG
Sbjct: 7 SSSASYGGGF-GGGSCQLGGGRGVSTCSTRFVSGG---SAGGYGGGVSCGFGGGAGSGFG 62
Query: 575 G 575
G
Sbjct: 63 G 63
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 489 bits (1259), Expect = e-138
Identities = 268/424 (63%), Positives = 316/424 (74%), Gaps = 15/424 (3%)
Query: 37 SSSKGSLGGGFSSGGFSGGSFSRGSS---GGGCFGGSSGGYGGLGGFGGGSFRGSYGSSS 93
SS KGS G G GG GGS SR SS GG C S+ G GG S S G+
Sbjct: 12 SSMKGSCGIG---GGIGGGS-SRISSVLAGGSCRAPSTYG----GGLSVSSRFSSGGACG 63
Query: 94 FGGSYGGSFGGGSFGGGSFGGGSFGGGGFG-GGGFGGGFGGGFGGDGGLLSGNEKVTMQN 152
GG YGG F S G FGGG GG G G GGG G GFGGGF G GLL G+EKVTMQN
Sbjct: 64 LGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVTMQN 123
Query: 153 LNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILN 212
LNDRLASYLDKVRALEE+N +LE KI++WY++ S E +DYS Y+KTI+DL+N+I+
Sbjct: 124 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPS---EIKDYSPYFKTIEDLRNKIIA 180
Query: 213 LTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQ 272
T +NA +LQIDNARLAADDFR KYE+E+ALRQ+VEAD+NGLRRVLDELTL + DLEMQ
Sbjct: 181 ATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQ 240
Query: 273 IESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQN 332
IE L EELAYL+KNHEEEM LR + GDVNVEM+AAPGVDL+++LN MR QYEQ+AE+N
Sbjct: 241 IEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKN 300
Query: 333 RKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEAS 392
R+DAE WF K++EL E+ +N E + S +SE+TELRR +Q LEIELQSQL++K SLE S
Sbjct: 301 RRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENS 360
Query: 393 LAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSL 452
L ET+GRYC+QLSQIQ I ++EEQL Q+R E E Q+ EYQ LLD+K RLE EI TYR L
Sbjct: 361 LEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRL 420
Query: 453 LEGE 456
LEGE
Sbjct: 421 LEGE 424
Score = 71.6 bits (174), Expect = 2e-12
Identities = 44/101 (43%), Positives = 51/101 (50%), Gaps = 9/101 (8%)
Query: 458 SSGGGGRGGGSFGGGYGGGSS------GGGS--SGGGHGGGHGGSSGGGYGGGSSGGGSS 509
+S +G GGG GGGSS GGS + +GGG SS GG GG
Sbjct: 9 TSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGY 68
Query: 510 GGGYGGGSSSG-GHGGSSSGGYGGGSSGGGGGGYGGGSSGG 549
GGG+ SS G G GG GG G G GG G G+GGG +GG
Sbjct: 69 GGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGG 109
Score = 70.5 bits (171), Expect = 4e-12
Identities = 44/98 (44%), Positives = 49/98 (50%), Gaps = 15/98 (15%)
Query: 456 EGSSG-GGGRGGGS------FGGG-------YGGGSSGGGSSGGGHGGGHGGSSGGGYGG 501
+GS G GGG GGGS GG YGGG S G G GG GGG+
Sbjct: 15 KGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSS 74
Query: 502 GSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGG 539
SS G GGGYGGG + G GG G+GGG +GG G
Sbjct: 75 SSSFGSGFGGGYGGGLGA-GFGGGLGAGFGGGFAGGDG 111
Score = 68.2 bits (165), Expect = 2e-11
Identities = 44/97 (45%), Positives = 49/97 (50%), Gaps = 14/97 (14%)
Query: 472 GYGGGSSGGGSSGGGHGGGHGGSSGGGYGGG-------SSGGGSS-GGGYGGGSSSGGHG 523
G GGG GG S G + YGGG SSGG GGGYGGG SS
Sbjct: 19 GIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSF 78
Query: 524 GSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGG 560
GS G+GGG GG G G+GGG G+ GGG+ GG
Sbjct: 79 GS---GFGGGYGGGLGAGFGGGL---GAGFGGGFAGG 109
Score = 60.5 bits (145), Expect = 4e-09
Identities = 30/60 (50%), Positives = 34/60 (56%)
Query: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS 517
SSGG GG +GGG+ SS G GGG+GGG G GGG G G GG + G G GS
Sbjct: 57 SSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGS 116
Score = 58.9 bits (141), Expect = 1e-08
Identities = 41/91 (45%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 479 GGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS--SSGGHGGSSSGGYGGG--S 534
G GGG GGG S GG + GGG S SSGG G GGYGGG S
Sbjct: 16 GSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLG-GGYGGGFSS 74
Query: 535 SGGGGGGYGGGSSGG-GSSSGGGYGGGSSSG 564
S G G+GGG GG G+ GGG G G G
Sbjct: 75 SSSFGSGFGGGYGGGLGAGFGGGLGAGFGGG 105
Score = 53.1 bits (126), Expect = 7e-07
Identities = 37/84 (44%), Positives = 41/84 (48%), Gaps = 13/84 (15%)
Query: 494 SSGGGYGGGSSGGGSSGGG------YGGGS----SSGGHGGSSSGGYGGGSSGGGGGGYG 543
SS G GGG GG GGS S+ G G S S + G + G GGGYG
Sbjct: 10 SSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYG 69
Query: 544 GG---SSGGGSSSGGGYGGGSSSG 564
GG SS GS GGGYGGG +G
Sbjct: 70 GGFSSSSSFGSGFGGGYGGGLGAG 93
Score = 52.8 bits (125), Expect = 9e-07
Identities = 38/88 (43%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 496 GGGYGGGSSGGGS--SGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSS 553
GGG GGGSS S +GG S+ GG G S S + G + G GGGYGGG S SS
Sbjct: 21 GGGIGGGSSRISSVLAGGSCRAPSTYGG-GLSVSSRFSSGGACGLGGGYGGGFSSS-SSF 78
Query: 554 GGGYGGGSSSGGHKSSSSGSVGESSSKG 581
G G+GG GG + G +G G
Sbjct: 79 GSGFGG-GYGGGLGAGFGGGLGAGFGGG 105
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/76 (46%), Positives = 35/76 (46%), Gaps = 18/76 (23%)
Query: 505 GGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGG-------SSGGGSSSGGGY 557
G GGG GGGSS S GGS YGGG SSGG GGGY
Sbjct: 16 GSCGIGGGIGGGSSR------ISSVLAGGSCRAPST-YGGGLSVSSRFSSGGACGLGGGY 68
Query: 558 GGGSSSGGHKSSSSGS 573
GGG SS SSS GS
Sbjct: 69 GGGFSS----SSSFGS 80
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 488 bits (1257), Expect = e-138
Identities = 269/431 (62%), Positives = 315/431 (73%), Gaps = 14/431 (3%)
Query: 48 SSGGFSGGSFSRGS---SGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGG 104
SS F GGS GS GGG GGS G GG S R + SS GG YGG
Sbjct: 9 SSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSAR--FVSSGSGGGYGGGMRV 66
Query: 105 GSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGG-DGGLLSGNEKVTMQNLNDRLASYLDK 163
FGGG+ GS GGGFGGG GGGFGGGFGG DGGLLSGNEK+TMQNLNDRLASYLDK
Sbjct: 67 CGFGGGA---GSVFGGGFGGG-VGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDK 122
Query: 164 VRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQ 223
VRALEE+N +LE KI +WY+K + DYS+Y+KTI++L+++I+ T DN+ ++L+
Sbjct: 123 VRALEEANADLEVKIHDWYQKQ--TPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILE 180
Query: 224 IDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYL 283
IDNARLAADDFRLKYENE+ALRQ VEADINGLRRVLDELTL + DLEMQIE L EELAYL
Sbjct: 181 IDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYL 240
Query: 284 KKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEK 343
KKNHEEEMK+ + G VNVEM+AAPGVDLT++L MR QYE +AE+NR+D EAWF K
Sbjct: 241 KKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSK 300
Query: 344 SKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQ 403
++EL E+ +N E I + K+EIT+LRR +Q LEIELQSQL++K LE SLAETE RY Q
Sbjct: 301 TEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQ 360
Query: 404 LSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGS--SGG 461
L QIQ I LE QL ++R E E QN EY+ LLDIK RLE EI TYRSLLEG+ + +G
Sbjct: 361 LQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGI 420
Query: 462 GGRGGGSFGGG 472
G R S GGG
Sbjct: 421 GIREASSGGGG 431
Score = 79.7 bits (195), Expect = 7e-15
Identities = 47/102 (46%), Positives = 52/102 (50%), Gaps = 15/102 (14%)
Query: 473 YGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGS-------SGGGYGGGSSSGGHGGS 525
+GGGS+ GGS G GG GGS GG G S S SGGGYGGG G GG
Sbjct: 13 FGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGG 72
Query: 526 SSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHK 567
+ +GGG GG GGG+GGG GG GG SG K
Sbjct: 73 AGSVFGGGFGGGVGGGFGGGFGGG--------DGGLLSGNEK 106
Score = 71.2 bits (173), Expect = 2e-12
Identities = 42/90 (46%), Positives = 47/90 (52%), Gaps = 10/90 (11%)
Query: 465 GGGSFGGGY---GGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGG----GYGGGS 517
GGGS GG GGG GGGS GG G +S + SGGG GG G+GGG+
Sbjct: 14 GGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGA 73
Query: 518 SS---GGHGGSSSGGYGGGSSGGGGGGYGG 544
S GG GG GG+GGG GG GG G
Sbjct: 74 GSVFGGGFGGGVGGGFGGGFGGGDGGLLSG 103
Score = 68.6 bits (166), Expect = 2e-11
Identities = 42/91 (46%), Positives = 47/91 (51%), Gaps = 22/91 (24%)
Query: 494 SSGGGYGGGSSGGGS---SGGGYGGGSSSGGHGG-------------SSSGGYGGGSS-- 535
+S +GGGS+ GGS GGG+GGGS SGG G S GGYGGG
Sbjct: 8 TSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVC 67
Query: 536 --GGGGGGYGGGSSGGGSSSGGGYGGGSSSG 564
GGG G GG GGG GGG+GGG G
Sbjct: 68 GFGGGAGSVFGGGFGGG--VGGGFGGGFGGG 96
Score = 64.7 bits (156), Expect = 2e-10
Identities = 40/82 (48%), Positives = 45/82 (54%), Gaps = 15/82 (18%)
Query: 459 SGGGGRGGGSFGGGYGGGSSGGGS-------SGGGHGGG-----HGGSSGGGYGGGSSGG 506
+GGGG GGGS GG G S S SGGG+GGG GG +G +GGG G
Sbjct: 25 AGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGF--G 82
Query: 507 GSSGGGYGGGSSSGGHGGSSSG 528
G GGG+GGG GG GG SG
Sbjct: 83 GGVGGGFGGG-FGGGDGGLLSG 103
Score = 55.5 bits (132), Expect = 1e-07
Identities = 27/48 (56%), Positives = 30/48 (62%), Gaps = 2/48 (4%)
Query: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG 505
S GGG GGG G+GGG+ G GGG GGG GG GGG+GGG G
Sbjct: 54 SGSGGGYGGGMRVCGFGGGA--GSVFGGGFGGGVGGGFGGGFGGGDGG 99
Score = 47.4 bits (111), Expect = 4e-05
Identities = 29/49 (59%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
Query: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG 505
G GGG R G FGG G GS GG GGG GGG GG GGG GG SG
Sbjct: 58 GGYGGGMRVCG-FGG--GAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSG 103
Score = 46.6 bits (109), Expect = 6e-05
Identities = 27/52 (51%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 6 SSSKHYSSSRSGGGGGGGG--CGGGGGVSSLRISSSKGSLGGGFSSGGFSGG 55
+SS + SS SGGG GGG CG GGG S+ G +GGGF GGF GG
Sbjct: 46 ASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFG-GGFGGG 96
Score = 45.4 bits (106), Expect = 1e-04
Identities = 25/51 (49%), Positives = 30/51 (58%)
Query: 525 SSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVG 575
+SS +GGGS+ GG GGG GGGS SGGG S+ + SSGS G
Sbjct: 8 TSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGG 58
Score = 35.8 bits (81), Expect = 0.11
Identities = 23/47 (48%), Positives = 27/47 (57%), Gaps = 6/47 (12%)
Query: 534 SSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580
SS GGG GGS G GGG+GGGS SGG S S+ SS++
Sbjct: 10 SSTFGGGSTRGGSLLAG---GGGFGGGSLSGG---GGSRSISASSAR 50
Score = 35.4 bits (80), Expect = 0.15
Identities = 17/28 (60%), Positives = 18/28 (64%), Gaps = 3/28 (10%)
Query: 455 GEGSSGGGGRGG---GSFGGGYGGGSSG 479
G GS GGG GG G FGGG+GGG G
Sbjct: 72 GAGSVFGGGFGGGVGGGFGGGFGGGDGG 99
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 487 bits (1254), Expect = e-137
Identities = 263/432 (60%), Positives = 314/432 (72%), Gaps = 12/432 (2%)
Query: 31 VSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYG 90
+SS + + G+ G +F G+S GG F +S +G GFGGGS GS
Sbjct: 21 LSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASM-FGSSSGFGGGS--GSSM 77
Query: 91 SSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTM 150
+ G YG + GGGSFGG G GFGG GG G G DGGLLSG+EK TM
Sbjct: 78 AGGLGAGYGRALGGGSFGG--------LGMGFGGSPGGGSLGILSGNDGGLLSGSEKETM 129
Query: 151 QNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHG-NSHQGEPRDYSKYYKTIDDLKNQ 209
QNLNDRLASYLDKVRALEE+N ELE KI+EWYE G + DYSKYY I+DL+N+
Sbjct: 130 QNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNK 189
Query: 210 ILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADL 269
I++ + NA +LLQIDNARLAA+DFR+KYENE+ALRQ VEADINGLRRVLDELTLT+ DL
Sbjct: 190 IISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDL 249
Query: 270 EMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLA 329
EMQIESL EELAY+KKNHE+E++ R G+V+VEM+AAPGVDLT+LLN+MR+QYE +A
Sbjct: 250 EMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIA 309
Query: 330 EQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSL 389
EQNRKDAEAWF EKS EL EI N EQ+ S KSE+T+LRR Q LEIELQSQLA+K+SL
Sbjct: 310 EQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSL 369
Query: 390 EASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTY 449
E SLAE EG YC QLSQ+Q IS LE QL Q+RA+ E QN ++Q+LL++K RLE EI+TY
Sbjct: 370 EDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETY 429
Query: 450 RSLLEGEGSSGG 461
R LL+GE G
Sbjct: 430 RRLLDGEAQGDG 441
Score = 72.4 bits (176), Expect = 1e-12
Identities = 43/97 (44%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Query: 474 GGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSS-SGGHGGSSSGGYGG 532
G +S GS GG G G S GGG+ S G SSG G G GSS +GG G GG
Sbjct: 32 GMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGG 91
Query: 533 GSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSS 569
GS GG G G+GG GG G GG SG K +
Sbjct: 92 GSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKET 128
Score = 64.7 bits (156), Expect = 2e-10
Identities = 43/93 (46%), Positives = 45/93 (48%), Gaps = 11/93 (11%)
Query: 463 GRGGGSFGGGYGGGSSG-GGSSGGGHGGGH--GGSSGGGYGGGSSGGGSSGGGYGGGSSS 519
G S G GYGG + G G S GGG G SSG G G GSS G G GYG
Sbjct: 32 GMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRAL-- 89
Query: 520 GGHGGSSSGGYG---GGSSGGGGGGYGGGSSGG 549
GG S GG G GGS GGG G G+ GG
Sbjct: 90 ---GGGSFGGLGMGFGGSPGGGSLGILSGNDGG 119
Score = 62.0 bits (149), Expect = 1e-09
Identities = 43/97 (44%), Positives = 46/97 (47%), Gaps = 8/97 (8%)
Query: 489 GGHGGSSGGGYGGGSSG-GGSSGGGYGGGS---SSGGHGGSSSGGYGGGSSGGGGGGYGG 544
G S G GYGG + G G S GGG+ S SS G GG S GG G G GG
Sbjct: 32 GMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGG 91
Query: 545 GSSGG-GSSSGGGYGGGS---SSGGHKSSSSGSVGES 577
GS GG G GG GGGS SG SGS E+
Sbjct: 92 GSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKET 128
Score = 60.1 bits (144), Expect = 6e-09
Identities = 44/88 (50%), Positives = 46/88 (52%), Gaps = 9/88 (10%)
Query: 458 SSGGGGRGGGSFGGGY--GGGSSGGG--SSGGGHGGGHGGSSGGGYGGG---SSGGGSSG 510
SS G G GG +FG G GGG S S G GGG G S GG G G + GGGS G
Sbjct: 36 SSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFG 95
Query: 511 G-GYG-GGSSSGGHGGSSSGGYGGGSSG 536
G G G GGS GG G SG GG SG
Sbjct: 96 GLGMGFGGSPGGGSLGILSGNDGGLLSG 123
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/76 (46%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Query: 455 GEGSSGGGGRGGGS-FGGGYGGGSSGGGSSGGGHGGGHGGSSGGG-YGGGSSGGGSSGGG 512
G G+S GGG S FG G G G S GG G G+G + GGG +GG G G S GG
Sbjct: 48 GFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGG 107
Query: 513 YGGGSSSGGHGGSSSG 528
G SG GG SG
Sbjct: 108 GSLGILSGNDGGLLSG 123
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/77 (45%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 508 SSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGG---GYG---GGS 561
S G GYGG S+ G G S GG+ S G G+GGGS G S +GG GYG GG
Sbjct: 37 SVGSGYGG--SAFGFGASCGGGFSAASMFGSSSGFGGGS--GSSMAGGLGAGYGRALGGG 92
Query: 562 SSGGHKSSSSGSVGESS 578
S GG GS G S
Sbjct: 93 SFGGLGMGFGGSPGGGS 109
Score = 40.4 bits (93), Expect = 0.005
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 3/69 (4%)
Query: 516 GSSSGGHGGSSSGGYGGGSSGGG---GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572
G G S GYGG + G G GGG+ S G SS GG G S +GG +
Sbjct: 28 GRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGR 87
Query: 573 SVGESSSKG 581
++G S G
Sbjct: 88 ALGGGSFGG 96
Score = 37.7 bits (86), Expect = 0.029
Identities = 26/49 (53%), Positives = 28/49 (57%), Gaps = 5/49 (10%)
Query: 451 SLLEGEGSSGGGGRGGGSFGG-GYG-GGSSGGGSSG---GGHGGGHGGS 494
S+ G G+ G GGGSFGG G G GGS GGGS G G GG GS
Sbjct: 76 SMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGS 124
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 468 bits (1203), Expect = e-132
Identities = 252/403 (62%), Positives = 298/403 (73%), Gaps = 8/403 (1%)
Query: 81 GGGSFRGSYGSSSFGGSY--GGSFGGGSFGGGSFGG-GSFGGGGFGGGGFGGGFGGGFGG 137
G GS R G + F GS GGS G F GG GS GG GG G GF G
Sbjct: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
Query: 138 -DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHG-NSHQGEPRD 195
+GGLLSGNEKVTMQNLNDRLASYLD VRALEE+N ELE KIK WYEK+G S +G D
Sbjct: 77 SEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHD 136
Query: 196 YSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGL 255
YS+Y+ TI+DLKN+I++ TT NAN++LQIDNARLAADDFRLKYENE+ L Q+VEADINGL
Sbjct: 137 YSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGL 196
Query: 256 RRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLT 315
RRVLDELTL + D E+Q ESL+EE+ YLKKNHEEEMK L+ + G+VNVEMNAAPGVDL
Sbjct: 197 RRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLA 256
Query: 316 QLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQAL 375
LLNNMR++YE LAEQNRKDAEAWFNEKS L +I ++ + +S++TE+RR +Q L
Sbjct: 257 VLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTL 316
Query: 376 EIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQL 435
EI+LQS +A K SLE SL ETE YC QL+QIQAQI ALEEQL Q+R ETE Q EY+ L
Sbjct: 317 EIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHL 376
Query: 436 LDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSS 478
LD+K+ LE EI+TY L++G+G+S +G FG G G SS
Sbjct: 377 LDVKVHLEKEIETYCRLIDGDGNSCSKSKG---FGSGSPGNSS 416
Score = 40.4 bits (93), Expect = 0.005
Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 500 GGGSSGGGSSGGGYGGGSSSGGH--GGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSG-GG 556
G GS + G G+ G S+ GG G S GGG GG + GG+ G + G G
Sbjct: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
Query: 557 YGGGSSSGGHK 567
GG SG K
Sbjct: 77 SEGGLLSGNEK 87
Score = 38.1 bits (87), Expect = 0.023
Identities = 26/68 (38%), Positives = 29/68 (42%)
Query: 465 GGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGG 524
G GS GG G S+ GG G S G G GS GGS GG G ++ G G
Sbjct: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
Query: 525 SSSGGYGG 532
S G G
Sbjct: 77 SEGGLLSG 84
Score = 37.4 bits (85), Expect = 0.038
Identities = 29/73 (39%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
Query: 452 LLEGEGS----SGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507
L G GS +GG G G S GG GS + GGG G GGS GG G ++ G
Sbjct: 14 LRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG 73
Query: 508 SSGGGYGGGSSSG 520
+G GG SG
Sbjct: 74 FAGS--EGGLLSG 84
Score = 36.2 bits (82), Expect = 0.086
Identities = 21/64 (32%), Positives = 27/64 (42%)
Query: 486 GHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGG 545
G G + G G+ G S+ GGS G + GG G G + GG+ G G
Sbjct: 17 GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAG 76
Query: 546 SSGG 549
S GG
Sbjct: 77 SEGG 80
Score = 35.0 bits (79), Expect = 0.19
Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Query: 478 SGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGG 537
SG GS +GG G +G GGS G GGG S G + G G + G
Sbjct: 16 SGAGSVRPLNGGA--GFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG 73
Query: 538 GGGGYGGGSSG 548
G GG SG
Sbjct: 74 FAGSEGGLLSG 84
Score = 32.3 bits (72), Expect = 1.2
Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 6/79 (7%)
Query: 482 SSGGGH-----GGGHGGSSGGGYG-GGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSS 535
S+G H G G GG G GSS G S G + GG GS GG G +
Sbjct: 6 SNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGA 65
Query: 536 GGGGGGYGGGSSGGGSSSG 554
G G S GG SG
Sbjct: 66 LGNAACIGFAGSEGGLLSG 84
Score = 32.3 bits (72), Expect = 1.2
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
Query: 518 SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGY----GGGSSSGGHKSSSSGS 573
S+G G G GG G+ G S+ GGS +G + GGG S S + G+
Sbjct: 6 SNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGA 65
Query: 574 VGESSSKG 581
+G ++ G
Sbjct: 66 LGNAACIG 73
Score = 31.6 bits (70), Expect = 2.1
Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 3/71 (4%)
Query: 459 SGGGGRGGGSFGGGYGGGSSGGGSSGGGHGG-GHGGSSGGGYGGGSSGGGSSGGGYGGGS 517
SG G + G G+ G S+ GGS G GG G GG +GG G
Sbjct: 16 SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIG-- 73
Query: 518 SSGGHGGSSSG 528
+G GG SG
Sbjct: 74 FAGSEGGLLSG 84
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 463 bits (1192), Expect = e-130
Identities = 254/388 (65%), Positives = 294/388 (75%), Gaps = 7/388 (1%)
Query: 70 SSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG-GSFGGGSFGGGGFGGGGFG 128
SS G G GGGS R S S GG GS GS GG GS GGS + G G
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLS--GGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGS-G 66
Query: 129 GGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNS 188
GG+G FGG GLL+G EK TMQNLNDRLASYLDKVRALEE+N ELE KI++WY++
Sbjct: 67 GGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQA-- 124
Query: 189 HQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSV 248
G RDYS+YY+TI++L+N+IL T DNANILLQIDNARLAADDFR K+E E ALR SV
Sbjct: 125 -PGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSV 183
Query: 249 EADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNA 308
EADINGLRRVLDELTL +ADLEMQIE+L EELAYLKKNHEEEM LR G++NVEM+A
Sbjct: 184 EADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDA 243
Query: 309 APGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITEL 368
APGVDL+++LN MR QYE++AE+NRKDAE WF K++EL E+ N E + S KSEI+EL
Sbjct: 244 APGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISEL 303
Query: 369 RRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQ 428
RR +QALEIELQSQL++K SLE +LAETE RYCVQLSQIQ I ++EEQL Q+R E E Q
Sbjct: 304 RRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQ 363
Query: 429 NTEYQQLLDIKIRLENEIQTYRSLLEGE 456
N EY+ LLD+K RLE EI TYR LLEGE
Sbjct: 364 NQEYKILLDVKTRLEQEIATYRRLLEGE 391
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/79 (40%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
Query: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510
S+ G GG R GG G GS GS+GG GS+ GG S SG
Sbjct: 13 SIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGL------GSTLGGSSYSSCYSFGSG 66
Query: 511 GGYGGGSSSGGHGGSSSGG 529
GGY GSS GG G +GG
Sbjct: 67 GGY--GSSFGGVDGLLAGG 83
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/82 (40%), Positives = 38/82 (46%), Gaps = 10/82 (12%)
Query: 477 SSGGGSSGGGHGGGHGGSS---GGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGG 533
SS G GGG +S GG G GS GS+GG GS+ GG SS Y G
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGL---GSTLGGSSYSSC--YSFG 64
Query: 534 SSGGGGGGYGG--GSSGGGSSS 553
S GG G +GG G GG +
Sbjct: 65 SGGGYGSSFGGVDGLLAGGEKA 86
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 503 SSGGGSSGGGYGGGSSSGG---HGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGG 559
SS G GGGSS GG +G GS+GG G GG S S G G G
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
Query: 560 GSSSGG 565
GSS GG
Sbjct: 70 GSSFGG 75
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/69 (42%), Positives = 31/69 (44%), Gaps = 6/69 (8%)
Query: 493 GSSGGGYGGGSSGGGSSGGGYGGGS----SSGGHGGSSSG-GYGGGSSGGGGGGYGGGSS 547
GSSG G GG S GG G GS S+GG G + G Y S G GGGYG
Sbjct: 16 GSSGLG-GGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFG 74
Query: 548 GGGSSSGGG 556
G GG
Sbjct: 75 GVDGLLAGG 83
Score = 37.7 bits (86), Expect = 0.029
Identities = 31/64 (48%), Positives = 33/64 (51%), Gaps = 8/64 (12%)
Query: 518 SSGGHGGSS------SGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSS 571
SSG GGSS SGG G GS G G G GS+ GGSS Y G S GG+ SS
Sbjct: 17 SSGLGGGSSRTSCRLSGGLGAGSCRLGSAG-GLGSTLGGSSYSSCYSFG-SGGGYGSSFG 74
Query: 572 GSVG 575
G G
Sbjct: 75 GVDG 78
Score = 34.3 bits (77), Expect = 0.33
Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 517 SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGG--YGGGSSSGGHKSSSSGSV 574
SSS G S GG +S GG G GS GS+ G G GG S S + S G
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGY 69
Query: 575 GES 577
G S
Sbjct: 70 GSS 72
Score = 31.2 bits (69), Expect = 2.8
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Query: 530 YGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGS----SSGGHKSSSSGS 573
+ SS G G GGGSS GG G GS S+GG S+ GS
Sbjct: 8 FTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGS 55
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 459 bits (1181), Expect = e-129
Identities = 252/404 (62%), Positives = 300/404 (74%), Gaps = 16/404 (3%)
Query: 77 LGGFGG-GSFRGSYGSSSFG-GSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGG 134
LG GG GS R S G + FG G+ G G GS +FGG S GG+GGG GGG
Sbjct: 12 LGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSS------SAGGYGGGLGGG 65
Query: 135 F-------GGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHG- 186
G + GLLSGNEKVTMQNLNDRLASYL+ VRALEE+N +LE KIK WYEK G
Sbjct: 66 SASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGP 125
Query: 187 NSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQ 246
S +G DYS+Y+ ID+LKNQI++ TT NA+++LQ DNARL ADDFRLK+ENE+AL Q
Sbjct: 126 GSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQ 185
Query: 247 SVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEM 306
SVEADINGLRRVLDELTL + DLE+Q+E+L+EELAYLKKNHEEEMK L+ + G+VNVEM
Sbjct: 186 SVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEM 245
Query: 307 NAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEIT 366
NAAPGVDLT LLNNMR++YE LAEQNR+DAEAWFNEKS L +I ++ +S ++E+
Sbjct: 246 NAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELI 305
Query: 367 ELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETE 426
E++R +Q LEIELQS LA K SLE SL ETE YC QL+QIQAQI ALEEQL Q+R ETE
Sbjct: 306 EMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETE 365
Query: 427 CQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFG 470
Q EY+QLLDIK+ LE EI+TY L++GE S +G G G
Sbjct: 366 GQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPG 409
Score = 47.8 bits (112), Expect = 3e-05
Identities = 30/66 (45%), Positives = 38/66 (57%), Gaps = 4/66 (6%)
Query: 497 GGYGGGSSGGGSSGG-GYGGGSSSG--GHGGSSSGGYGGGSSGGG-GGGYGGGSSGGGSS 552
G GG S SSGG G+G G++ G G G S +GG SS GG GGG GGGS+ +
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
Query: 553 SGGGYG 558
+G +G
Sbjct: 73 TGNEHG 78
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/69 (42%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 472 GYGGGSSGGGSSGGGHGGGHGGSSG-GGYGGGSS---GGGSSGGGYGGGSSSGGHGGSSS 527
G GG+ S GG G G G + G G G G S GG SS GGYGGG G G +S
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGL---GGGSASC 69
Query: 528 GGYGGGSSG 536
+ G G
Sbjct: 70 AAFTGNEHG 78
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/62 (45%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 457 GSSGGGGRGGGSFGG-GYGGGSSGGGSS-GGGHGGGHGGSSG-GGYGGGSSGGGSSGGGY 513
GS GG G S GG G+G G++ G G G GGSS GGYGGG GG +S +
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
Query: 514 GG 515
G
Sbjct: 73 TG 74
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/59 (45%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 507 GSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGG-GYGGGSSGGGSSSGGGYGGGSSSG 564
GS GG SSGG G+G G++ G G G G + GGSSS GGYGGG G
Sbjct: 13 GSCGGTGSVRLSSGG------AGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGG 65
Score = 40.4 bits (93), Expect = 0.005
Identities = 27/59 (45%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 461 GGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSS 519
G G GS GG G G++ G G G G S +GG SS GG GGG GGGS+S
Sbjct: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCA--FGGSSSAGG-YGGGLGGGSAS 68
Score = 33.9 bits (76), Expect = 0.43
Identities = 20/43 (46%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGH-GGGHGGSSG 496
G GS GG S GGYGGG GG +S G HG SG
Sbjct: 40 GIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAFTGNEHGLLSG 82
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 450 bits (1157), Expect = e-126
Identities = 247/412 (59%), Positives = 293/412 (71%), Gaps = 21/412 (5%)
Query: 69 GSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFG 128
GS YGG FG G+ S G S G + +FGG S GG + GGG
Sbjct: 19 GSLRLYGGGTSFGTGN---SCGISGIGSGFSSAFGGSSSGGNT-----------GGGNPC 64
Query: 129 GGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHG-N 187
GF + GLLSGNEKVTMQNLNDRLASYLD V ALEE+N +LE KIK WYEK G
Sbjct: 65 AGF---TVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPG 121
Query: 188 SHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQS 247
S +G DYS+Y+ IDDLKNQI+ TT NAN +LQIDNARL ADDFRLKYENE+AL QS
Sbjct: 122 SCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQS 181
Query: 248 VEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMN 307
VEAD+NGLRRVLDE+TL + DLE+Q E+L+EE+ YLKKNH+EEM+ L+ + G+VNVEMN
Sbjct: 182 VEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMN 241
Query: 308 AAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITE 367
AAPGVDLT LLNNMR++YE LAEQNR+DAEAWFNEKS L +I ++ +S ++E+TE
Sbjct: 242 AAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTE 301
Query: 368 LRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETEC 427
++R +Q LEIELQS LA K SLE SL ETE YC QL+QIQAQI ALEEQL Q+R ETE
Sbjct: 302 MKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEG 361
Query: 428 QNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSG 479
Q EY+QLLDIK+ LE EI+TY L+ G G + GG YG G+ G
Sbjct: 362 QKLEYEQLLDIKLHLEKEIETYCLLI---GGDDGACKSGGYKSKDYGSGNVG 410
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 10/60 (16%)
Query: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572
YGGG+S G G S G G G G S+ GGSSSGG GGG+ G + G
Sbjct: 24 YGGGTSFGT----------GNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERG 73
Score = 37.0 bits (84), Expect = 0.050
Identities = 22/44 (50%), Positives = 28/44 (63%), Gaps = 3/44 (6%)
Query: 473 YGGGSS-GGGSSGGGHGGGHGGSS--GGGYGGGSSGGGSSGGGY 513
YGGG+S G G+S G G G G SS GG GG++GGG+ G+
Sbjct: 24 YGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGF 67
Score = 36.2 bits (82), Expect = 0.086
Identities = 33/88 (37%), Positives = 40/88 (45%), Gaps = 20/88 (22%)
Query: 1 MSVRYSSSKHYS-------SSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFS 53
MS+R SS+ S S R GGG G G G+S + G GFSS
Sbjct: 1 MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGI---------GSGFSSA--F 49
Query: 54 GGSFSRGSSGGG--CFGGSSGGYGGLGG 79
GGS S G++GGG C G + G L G
Sbjct: 50 GGSSSGGNTGGGNPCAGFTVNERGLLSG 77
Score = 35.4 bits (80), Expect = 0.15
Identities = 22/43 (51%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
Query: 499 YGGGSS-GGGSSGG--GYGGGSSSGGHGGSSSGGYGGGSSGGG 538
YGGG+S G G+S G G G G SS G SS G GGG+ G
Sbjct: 24 YGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAG 66
Score = 35.0 bits (79), Expect = 0.19
Identities = 20/44 (45%), Positives = 24/44 (54%)
Query: 453 LEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSG 496
L G G+S G G G G G G S+ GGSS GG+ GG +G
Sbjct: 23 LYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAG 66
Score = 30.4 bits (67), Expect = 4.7
Identities = 18/36 (50%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 542 YGGGSSGGGSSSGG--GYGGGSSSGGHKSSSSGSVG 575
YGGG+S G +S G G G G SS SSS G+ G
Sbjct: 24 YGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTG 59
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 434 bits (1117), Expect = e-122
Identities = 234/386 (60%), Positives = 286/386 (74%), Gaps = 16/386 (4%)
Query: 84 SFRGSYGSSSFGGSYGGS--FGGG-SFGGGSFGGGSFGGG----------GFGGGGFGGG 130
S+R S +SSFGG GGS FG G +F S GGS G G G +GGG
Sbjct: 5 SYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGG 64
Query: 131 FGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQ 190
+GG GLL+GNEK+TMQNLNDRLASYLDKVRALE +N ELE KI++WY+K G
Sbjct: 65 YGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQG---P 121
Query: 191 GEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEA 250
G RDYS YY TI DL+++IL T +N+ I+LQIDNARLAADDFR K+E E ALR SVEA
Sbjct: 122 GPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181
Query: 251 DINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAP 310
DINGLRRVLDELTL + DLEMQIE L EELAYLKKNHEEE+ LR G V+VE+++AP
Sbjct: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAP 241
Query: 311 GVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRR 370
G DL ++L++MRSQYE +AEQNRKDAEAWF +++EL E+ + EQ+ +SE+T+LRR
Sbjct: 242 GTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRR 301
Query: 371 NVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNT 430
+Q LEIELQSQL++K +LE +LAETE R+ QL+ IQA IS +E QL +RA++E QN
Sbjct: 302 TLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQ 361
Query: 431 EYQQLLDIKIRLENEIQTYRSLLEGE 456
EYQ+L+DIK RLE EI TYRSLLEG+
Sbjct: 362 EYQRLMDIKSRLEQEIATYRSLLEGQ 387
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 448 TYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507
T S + +S GG GGGS +G G + S G GG G S SS G
Sbjct: 2 TSYSYRQSSATSSFGGLGGGSVR--FGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSG 59
Query: 508 SSGGGYGG 515
+ GGGYGG
Sbjct: 60 AYGGGYGG 67
Score = 38.5 bits (88), Expect = 0.017
Identities = 31/77 (40%), Positives = 35/77 (45%), Gaps = 9/77 (11%)
Query: 499 YGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGG---GSSSGG 555
Y S SS GG GGGS G G + + S GG GG G S SSS G
Sbjct: 4 YSYRQSSATSSFGGLGGGSVRFGPGVA----FRAPSIHGGSGGRGVSVSSARFVSSSSSG 59
Query: 556 GYGGGSSSGGHKSSSSG 572
YGGG GG ++S G
Sbjct: 60 AYGGG--YGGVLTASDG 74
Score = 34.3 bits (77), Expect = 0.33
Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 477 SSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSG 536
SS S GG GG G + S GGS G G SS+ SSSG YGGG G
Sbjct: 9 SSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGV-SVSSARFVSSSSSGAYGGGYGG 67
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 416 bits (1070), Expect = e-116
Identities = 240/406 (59%), Positives = 281/406 (69%), Gaps = 19/406 (4%)
Query: 53 SGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSF 112
SGGS S G G SGG G G G GS SSF + G GGSF
Sbjct: 6 SGGSRRICSRTGS--GRLSGG--GTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNS-- 59
Query: 113 GGGSFGGGGFGGGGFGGGFGGGF-GGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESN 171
GGG G G GF G + LLSGNEKVTMQNLNDRLASYLD V ALEE+N
Sbjct: 60 -----------GGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEAN 108
Query: 172 YELEGKIKEWYEK-HGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLA 230
+LE KIK YEK S + DYS+Y+ I+DLK QI + T NA+I+LQ DNARL
Sbjct: 109 ADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLT 168
Query: 231 ADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEE 290
ADDFRLKYENE+AL SVEAD +GLRRVLDELTL DLE+Q E+L+EEL YLKK+HEEE
Sbjct: 169 ADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEE 228
Query: 291 MKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTE 350
M+ L+ + G+VNVEMNA PGVDLT LLNNMR++YE LAEQNRKDAEAWFNE+S L +
Sbjct: 229 MEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQ 288
Query: 351 IDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQ 410
I ++ ++ ++E+TEL+RN+Q LEIELQS +A+K S E SLAETEG YC QL QIQ Q
Sbjct: 289 ISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQ 348
Query: 411 ISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGE 456
I +EEQLQQIR ETE Q EY+QLLD+KI LE EI Y +LL+GE
Sbjct: 349 IGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGE 394
Score = 32.3 bits (72), Expect = 1.2
Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 455 GEGSSGGGGRG--GGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGG 506
G G GGG G G+ G G SS + G GG +SGGG G G+ G
Sbjct: 17 GSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAG 70
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 11/80 (13%)
Query: 1 MSVRYSSSKHYSSSRSGGG----GGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGS 56
MS R S SR+G G GG G G V S SS +L G SGGS
Sbjct: 1 MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTL-----EGISSGGS 55
Query: 57 FSRGSSGGGCFGGSSGGYGG 76
F +SGGG G+ G+ G
Sbjct: 56 FC--NSGGGLGSGACAGFLG 73
Score = 30.4 bits (67), Expect = 4.7
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 514 GGGSSSGGHGGSSSGGY--GGGSSGGGGGGYGGGSSGGG-SSSGGGYGGGSSSG 564
G G SGG G +G G G+ G SSGG +SGGG G G+ +G
Sbjct: 17 GSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAG 70
Score = 30.0 bits (66), Expect = 6.1
Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 7/74 (9%)
Query: 459 SGGGGR-----GGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513
SGG R G G GG G +G G G + G GGS +SGGG
Sbjct: 6 SGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSF--CNSGGGL 63
Query: 514 GGGSSSGGHGGSSS 527
G G+ +G G S
Sbjct: 64 GSGACAGFLGNEHS 77
Score = 30.0 bits (66), Expect = 6.1
Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 480 GGSSGGGHGGGHGGSSGGGYG--GGS----SGGGSSGGGYGGGSSSGGHGGSSSGGYGGG 533
GGS G G SGGG G G+ SG SS G SSGG +S GG G G
Sbjct: 7 GGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSG 66
Query: 534 SSGG 537
+ G
Sbjct: 67 ACAG 70
Score = 30.0 bits (66), Expect = 6.1
Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 8/56 (14%)
Query: 500 GGGSSGGGSSGGGYGGGSSSGGHGGSSS------GGYGGGSSGGGGGGYGGGSSGG 549
G G GG G G+ G+ G G SS G GGS GGG G G+ G
Sbjct: 17 GSGRLSGG--GTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAG 70
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 370 bits (950), Expect = e-102
Identities = 237/631 (37%), Positives = 343/631 (54%), Gaps = 85/631 (13%)
Query: 3 VRYSSSKHYSSSRSGGGGGG--GGCGGGGGVSSLRISSSKGSLGGGFSSGGFS--GGSFS 58
+ Y SS+R GGGGG CGGGGG S G+ GGGF S GGS S
Sbjct: 25 INYQRRTTSSSTRRSGGGGGRFSSCGGGGG--------SFGA-GGGFGSRSLVNLGGSKS 75
Query: 59 RGSS---GGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGG 115
S GGG G GGYGG GGFGGG F G GG GG GGG FGG GGG
Sbjct: 76 ISISVARGGGRGSGFGGGYGG-GGFGGGGFGG-------GGFGGGGIGGGGFGGFGSGGG 127
Query: 116 SFGGGGFGGGGFGGGFGGGFGGDGGL-----------------------LSGNEKVTMQN 152
FGGGGFGGGG+GGG+G GG+ + E+ +++
Sbjct: 128 GFGGGGFGGGGYGGGYGP-VCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKS 186
Query: 153 LNDRLASYLDKVRALEESNYELEGK--IKEWYEKHGNSHQGEPRDYSKYYKT-IDDLKNQ 209
LN++ AS++DKVR LE+ N L+ K + + + +H EP Y+++ I++L+ +
Sbjct: 187 LNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEP-----YFESFINNLRRR 241
Query: 210 ILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADL 269
+ L +D + + ++ N + +D+R KYE+E+ R + E + +++ +D +TK DL
Sbjct: 242 VDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDL 301
Query: 270 EMQIESLTEELAYLKKNHEEEMKDLRN-VSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQL 328
+ ++++L +E+ +L ++ E+ ++ +S +V + M+ +DL ++ +++QYE +
Sbjct: 302 QAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDI 361
Query: 329 AEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQS 388
A++++ +AE+ + K +EL + + + + K EI+EL R +Q L E+ + +
Sbjct: 362 AQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISN 421
Query: 389 LEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQT 448
L+ S+++ E R L + +++ LE+ LQQ + + +YQ+L++ K+ L+ EI T
Sbjct: 422 LQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIAT 481
Query: 449 YRSLLEGEGS---------------------SGGGGRGGGSFGGGYGGGSSGGGSSGGGH 487
YR+LLEGE S SGGG RGGG GGGYG G S GS GG +
Sbjct: 482 YRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGG--GGGYGSGGSSYGSGGGSY 539
Query: 488 GGGHGGSSG-GGYGGGSSGGGSSGGGYGGGSSSGGHG----GSSSGGYGGGSSGGGGGGY 542
G G GG G G YG G S GS GG YG G GGHG GSSSGGY GGS GGGGG
Sbjct: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSS 599
Query: 543 GGGSSGGGSSSGGGYGGGSSSGGHKSSSSGS 573
GG SGGGSS G G GSSSGG KSS S
Sbjct: 600 GGRGSGGGSSGGSIGGRGSSSGGVKSSGGSS 630
Score = 103 bits (256), Expect = 6e-22
Identities = 63/142 (44%), Positives = 70/142 (49%), Gaps = 16/142 (11%)
Query: 2 SVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGS 61
+V S S +++ GG GGGG G G G SS GS GG + SGG GG
Sbjct: 500 NVSVSVSTSHTTISGGGSRGGGGGGYGSG------GSSYGSGGGSYGSGGGGGGGRGSYG 553
Query: 62 SGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGG 121
SGG +G G YG GG GG GSYGS S G Y G GGG GGGS GG G
Sbjct: 554 SGGSSYGSGGGSYGSGGGGGG---HGSYGSGSSSGGYRGGSGGG-------GGGSSGGRG 603
Query: 122 FGGGGFGGGFGGGFGGDGGLLS 143
GGG GG GG GG+ S
Sbjct: 604 SGGGSSGGSIGGRGSSSGGVKS 625
Score = 96.3 bits (238), Expect = 7e-20
Identities = 61/143 (42%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Query: 1 MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRG 60
+SV S+S S GGGGGG G GG SS GS GG + SGG GG
Sbjct: 501 VSVSVSTSHTTISGGGSRGGGGGGYGSGG--------SSYGSGGGSYGSGGGGGGGRGSY 552
Query: 61 SSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFG--GGSFGGGSFG 118
SGG +G G YG GG GG GSYGS S G Y G GGG G GG GG
Sbjct: 553 GSGGSSYGSGGGSYGSGGGGGG---HGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSS 609
Query: 119 GGGFGGGGFGGGFGGGFGGDGGL 141
GG GG G G GG +
Sbjct: 610 GGSIGGRGSSSGGVKSSGGSSSV 632
Score = 75.9 bits (185), Expect = 1e-13
Identities = 57/142 (40%), Positives = 64/142 (45%), Gaps = 27/142 (19%)
Query: 464 RGGGSFGGGYGGGSSG--------GGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYG- 514
R G GGG+ GS+G SS GGG G S G GGGS G +GGG+G
Sbjct: 8 RSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFG---AGGGFGS 64
Query: 515 ------GGSSSGGHGGSSSGGYGGGSSGGGGGG-------YGGGSSGGGSSSGGGYGG-G 560
GGS S + GG G G GGG GG +GGG GGG GGG+GG G
Sbjct: 65 RSLVNLGGSKSISISVARGGGRGSGF-GGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFG 123
Query: 561 SSSGGHKSSSSGSVGESSSKGP 582
S GG G G GP
Sbjct: 124 SGGGGFGGGGFGGGGYGGGYGP 145
Score = 67.0 bits (162), Expect = 5e-11
Identities = 42/99 (42%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 11 YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS 70
Y S S G GGG G GGG GS G G SSGG+ GGS G GGG GG
Sbjct: 552 YGSGGSSYGSGGGSYGSGGG------GGGHGSYGSGSSSGGYRGGS---GGGGGGSSGGR 602
Query: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG 109
G G GG GG S G S GGS F ++ G
Sbjct: 603 GSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSG 641
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/56 (57%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Query: 532 GGSSGG-GGGGYGGG----SSGGGS-SSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581
GG S G GGGGYG G SGGGS SGGG GGG S G SS GS G S G
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSG 569
Score = 38.5 bits (88), Expect = 0.017
Identities = 19/46 (41%), Positives = 19/46 (41%)
Query: 539 GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584
GGG GG GG S G YG G S G G G S G Y
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSY 559
Score = 30.8 bits (68), Expect = 3.6
Identities = 23/69 (33%), Positives = 26/69 (37%), Gaps = 14/69 (20%)
Query: 525 SSSGGYGGGSSGGGGGGY--------------GGGSSGGGSSSGGGYGGGSSSGGHKSSS 570
S SG GG G G GG G SS GGG G + GG S S
Sbjct: 7 SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRS 66
Query: 571 SGSVGESSS 579
++G S S
Sbjct: 67 LVNLGGSKS 75
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 359 bits (922), Expect = 3e-99
Identities = 212/399 (53%), Positives = 266/399 (66%), Gaps = 21/399 (5%)
Query: 70 SSGGYGGLGGFGGGSFR-------GSYGSSSFGGSYG--GSFGGGSFGGGSFGGGSFGGG 120
S+G GL G GG R GS S G+ G S G G GS GS+
Sbjct: 11 STGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSS 70
Query: 121 GFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKE 180
GF G GG+ +G +G+EK TMQ LNDRLA+YL+KVR LE N ELE +I+E
Sbjct: 71 ECHTSGFVGS--GGWFCEGSF-NGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQE 127
Query: 181 WYEKHGNSHQGEPR---DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLK 237
WYE P DY Y+KTI+D + +IL ++NA ++LQIDNA+LAADDFR K
Sbjct: 128 WYEFQ------IPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTK 181
Query: 238 YENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNV 297
YE E++LRQ VEADINGLRR+LDELTL KADLE Q+ESL EEL LKKNHEEE+ LR
Sbjct: 182 YETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQ 241
Query: 298 STGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQ 357
+NVE++AAP VDL ++L +MR QYE L E NR+D EAWFN +++EL ++ ++ EQ
Sbjct: 242 LGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQ 301
Query: 358 ISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQ 417
+ ++EI ELRR V ALEIELQ+Q +++ SLE++LAETE RY QL+Q+Q IS +E Q
Sbjct: 302 LQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQ 361
Query: 418 LQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGE 456
L +IR + E QN EYQ LLD+K RLE EI TYR LLEGE
Sbjct: 362 LSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGE 400
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 355 bits (910), Expect = 8e-98
Identities = 208/407 (51%), Positives = 267/407 (65%), Gaps = 25/407 (6%)
Query: 68 GGSSGGYGGLGGFGGGSFRGS--YGSSSFG----GSYGGSFGGGSFGGGSFGGGSFGGGG 121
G SSG GG GGS R S Y SSS SF S G G S+
Sbjct: 9 GFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVG---LGRSSYRATS 65
Query: 122 ------FGGGGFGGGFGGGFGGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYEL 174
GGF + GG G G G+L+GNEK TMQ+LNDRLA YL+KVR LE+ N L
Sbjct: 66 CLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASL 125
Query: 175 EGKIKEWYEKHGNSHQGEPR---DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAA 231
E +I+EW E Q P DY Y++TI++L+ + L +NA ++++IDNA+LAA
Sbjct: 126 ESRIREWCE------QQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAA 179
Query: 232 DDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEM 291
DDFR KYE EV+LRQ VE+DINGLRR+LD+LTL K+DLE Q+ESL EEL LKKNHEEE+
Sbjct: 180 DDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEV 239
Query: 292 KDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEI 351
LR +NVE++AAP VDL ++L MR QYE L E NR+DAE W + +S+EL ++
Sbjct: 240 NSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQV 299
Query: 352 DNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQI 411
++ EQ+ S ++EI ELRR V ALEIELQ+Q +++ +LE++LAETE RY QL+Q+Q I
Sbjct: 300 VSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMI 359
Query: 412 SALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGS 458
+ +E QL +IRA+ E QN EYQ LLD++ RLE EI TYR LLE E S
Sbjct: 360 TNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDS 406
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 337 bits (865), Expect = 1e-92
Identities = 180/331 (54%), Positives = 234/331 (70%), Gaps = 3/331 (0%)
Query: 126 GFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKH 185
G G G G G +GNEK TMQ LNDRLASYL +VR LE+ N ELE +I+E H
Sbjct: 76 GISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQE--ASH 133
Query: 186 GNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALR 245
P DY +++TI++L+ +IL +NA +++ IDNA+LAADDFR KYE E+A+R
Sbjct: 134 SQVLTMTP-DYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMR 192
Query: 246 QSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVE 305
Q VEADINGLRR+LD+LTL KADLE Q+ESL EEL LKKNHEEE+ LR +N+E
Sbjct: 193 QLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIE 252
Query: 306 MNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEI 365
++AAP VDLT++L MR QYE + E NR+D E WFN + +EL ++ + EQ+ +Y+S+I
Sbjct: 253 VDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDI 312
Query: 366 TELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAET 425
+LRR V LEIELQ+Q +L+ SLE +L E+E RY QL+Q+Q I+ +E QL +IRA+
Sbjct: 313 IDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADL 372
Query: 426 ECQNTEYQQLLDIKIRLENEIQTYRSLLEGE 456
E QN EYQ LLD++ RLE EI TYRSLLE E
Sbjct: 373 ERQNQEYQVLLDVRARLEGEINTYRSLLENE 403
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 333 bits (853), Expect = 3e-91
Identities = 179/320 (55%), Positives = 233/320 (72%), Gaps = 9/320 (2%)
Query: 140 GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPR---DY 196
G +G+EK TMQ LNDRLASYL+KVR LE N ELE I+E S Q EP Y
Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE------RSQQQEPLLCPSY 103
Query: 197 SKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLR 256
Y+KTI++L+ +IL ++NA +++QIDNA+LAADDFR KY+ E++LRQ VE+DINGLR
Sbjct: 104 QSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLR 163
Query: 257 RVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQ 316
R+LDELTL K+DLE Q+ESL EEL LK NHE+E+ LR +NVE++AAP VDL +
Sbjct: 164 RILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNR 223
Query: 317 LLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALE 376
+LN RSQYE L E NR++ E WF +++EL ++ ++ EQ+ SY++EI ELRR V ALE
Sbjct: 224 VLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALE 283
Query: 377 IELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLL 436
IELQ+Q L+ SLE +L E+E RY QLSQ+Q+ I+ +E QL +IR++ E QN EYQ LL
Sbjct: 284 IELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLL 343
Query: 437 DIKIRLENEIQTYRSLLEGE 456
D++ RLE EI TYRSLLE E
Sbjct: 344 DVRARLECEINTYRSLLESE 363
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 332 bits (851), Expect = 6e-91
Identities = 179/320 (55%), Positives = 233/320 (72%), Gaps = 9/320 (2%)
Query: 140 GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEP---RDY 196
G +G+EK TMQ LNDRLASYL+KVR LE N ELE I+E S Q EP Y
Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE------RSQQQEPLVCASY 103
Query: 197 SKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLR 256
Y+KTI++L+ +IL ++NA +++QIDNA+LA+DDFR KYE E++LRQ VE+DINGLR
Sbjct: 104 QSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLR 163
Query: 257 RVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQ 316
R+LDELTL ++DLE Q+ESL EEL LK+NHE+E+ LR +NVE++AAP VDL Q
Sbjct: 164 RILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQ 223
Query: 317 LLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALE 376
+LN RSQYE L E NR++ E WF +++EL ++ ++ EQ+ SY++EI ELRR V ALE
Sbjct: 224 VLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALE 283
Query: 377 IELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLL 436
IELQ+Q L+ SLE +L E+E RY QLSQ+Q I+ +E QL +IR++ E QN EYQ LL
Sbjct: 284 IELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLL 343
Query: 437 DIKIRLENEIQTYRSLLEGE 456
D++ RLE EI TYRSLLE E
Sbjct: 344 DVRARLECEINTYRSLLESE 363
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 330 bits (845), Expect = 3e-90
Identities = 224/637 (35%), Positives = 327/637 (51%), Gaps = 87/637 (13%)
Query: 12 SSSRSGGGGGGGGCGGGGGV---------SSLRISSSKGSLGGGFSSGGFS-------GG 55
S R GGGGG G G V SS S G GGGF GGF GG
Sbjct: 9 SRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68
Query: 56 --SFSRGSSGGGCFGGSSGGYGGLGG-FGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSF 112
S S +GGG G++GG+GG GG FGGGS SFGG G F GG FGGG F
Sbjct: 69 TKSISISVAGGGGGFGAAGGFGGRGGGFGGGS--------SFGG--GSGFSGGGFGGGGF 118
Query: 113 GGGSFGG----GGFGGGGFGGGFGGGFGGDGGL-----------------------LSGN 145
GGG FGG GG GG G GGFG G G GG+ +
Sbjct: 119 GGGRFGGFGGPGGVGGLGGPGGFGPG-GYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQ 177
Query: 146 EKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDD 205
E+ ++ LN++ AS++DKVR LE+ N L+ K + + + + + Y ID
Sbjct: 178 EREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGY--IDS 235
Query: 206 LKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLT 265
LK + LT + + +++N + +D++ KYE+E+ R + E D L++ +D +
Sbjct: 236 LKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMI 295
Query: 266 KADLEMQIESLTEELAYLKKNHEEEMKDL-RNVSTGDVNVEMNAAPGVDLTQLLNNMRSQ 324
K +L+ +++ L +E+ +LK ++ E+ + ++V+ +V + M+ + +DL ++ +++Q
Sbjct: 296 KVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQ 355
Query: 325 YEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLA 384
YE++A++++++AEA ++ K +EL + + + + K EI+EL R +Q L+ E+
Sbjct: 356 YEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKK 415
Query: 385 LKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLEN 444
++++ ++A+ E R L + +++ LEE LQQ + + +YQ+L+++K+ L+
Sbjct: 416 QCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDV 475
Query: 445 EIQTYRSLLEGEGSSGGGGRGGG------------------SFGGGYG-GGSSGGGSSGG 485
EI TYR LLEGE G +FGG G G SSGGG S G
Sbjct: 476 EIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSG 535
Query: 486 GHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGG- 544
G GG G GG GG SGGGYG G SGG GS G GG SGGG G GG
Sbjct: 536 SSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGK 595
Query: 545 ----GSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGES 577
G S GGSSSGGGYG G GG SS GS GE+
Sbjct: 596 HSSGGGSRGGSSSGGGYGSG---GGGSSSVKGSSGEA 629
Score = 93.2 bits (230), Expect = 6e-19
Identities = 58/140 (41%), Positives = 66/140 (47%), Gaps = 27/140 (19%)
Query: 463 GRGGGSFGGGYGGGSSGGGSSGGG-------------HGGGHGGSSGGGYG-------GG 502
GRGGG GGG+ G SSG GG HGGG GG GGG+G GG
Sbjct: 11 GRGGG--GGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68
Query: 503 SSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSS 562
+ S G GGG + G G GG+GGGSS GGG G+ GG GG GG+GGG
Sbjct: 69 TKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGG-----GGFGGGRF 123
Query: 563 SGGHKSSSSGSVGESSSKGP 582
G G +G GP
Sbjct: 124 GGFGGPGGVGGLGGPGGFGP 143
Score = 87.8 bits (216), Expect = 2e-17
Identities = 58/129 (44%), Positives = 63/129 (48%), Gaps = 6/129 (4%)
Query: 8 SKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCF 67
S + +S + GG GG G GGG SS S G G G GGS S G G G
Sbjct: 509 SSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSG-- 566
Query: 68 GGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGF 127
GGS G YG GG GGS G G S GG + S GGGS GG S GGG +G GG G
Sbjct: 567 GGSGGRYGSGGGSKGGSISGG-GYGSGGGKH--SSGGGSRGGSSSGGG-YGSGGGGSSSV 622
Query: 128 GGGFGGGFG 136
G G FG
Sbjct: 623 KGSSGEAFG 631
Score = 79.7 bits (195), Expect = 7e-15
Identities = 57/129 (44%), Positives = 63/129 (48%), Gaps = 30/129 (23%)
Query: 6 SSSKHYSSSRSGGGGGG------GGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSR 59
SS YSS S G GG GG GGGG +S GGG+ SGG SGG +
Sbjct: 527 SSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSIS-----------GGGYGSGGGSGGRYG- 574
Query: 60 GSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGG 119
SGGG GGS G GG+G G + S G GGS GGS GG +G G GGGS
Sbjct: 575 --SGGGSKGGSISG----GGYGSGGGKHSSG----GGSRGGSSSGGGYGSG--GGGSSSV 622
Query: 120 GGFGGGGFG 128
G G FG
Sbjct: 623 KGSSGEAFG 631
Score = 75.9 bits (185), Expect = 1e-13
Identities = 51/105 (48%), Positives = 55/105 (52%), Gaps = 6/105 (5%)
Query: 2 SVRYSSSKHYSSSRSGGGGGGGGCGGG---GGVSSLRISSSKGSLGGGFSSGGFSGGSFS 58
S Y S S SR G GGGG GGG GG S R S GS GG S GG+ G
Sbjct: 536 SSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGG-G 594
Query: 59 RGSSGGGCFGGSSGGYG-GLGGFGGGSFRGSYGSSSFGGSYGGSF 102
+ SSGGG GGSS G G G GG G S +GS G +FG S SF
Sbjct: 595 KHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSG-EAFGSSVTFSF 638
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 327 bits (839), Expect = 1e-89
Identities = 177/320 (55%), Positives = 232/320 (72%), Gaps = 9/320 (2%)
Query: 140 GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPR---DY 196
G +G+EK TMQ LNDRLASYL+KVR LE N ELE I+E S Q EP Y
Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE------RSQQQEPLLCPSY 103
Query: 197 SKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLR 256
Y+KTI++L+ +IL ++NA +++QIDNA+LAADDFR KY+ E +LRQ VE+DIN LR
Sbjct: 104 QSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLR 163
Query: 257 RVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQ 316
R+LDELTL ++DLE Q+ESL EEL LK+NHE+E+ LR +NVE++AAP VDL Q
Sbjct: 164 RILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQ 223
Query: 317 LLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALE 376
+LN R+QYE L E NR++ E WF +++EL ++ ++ EQ+ SY++EI ELRR V ALE
Sbjct: 224 VLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALE 283
Query: 377 IELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLL 436
IELQ+Q L+ SLE +L E+E RY QLSQ+Q+ I+ +E QL +IR++ E QN EYQ LL
Sbjct: 284 IELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLL 343
Query: 437 DIKIRLENEIQTYRSLLEGE 456
D++ RLE EI TYRSLLE E
Sbjct: 344 DVRARLECEINTYRSLLESE 363
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 326 bits (836), Expect = 3e-89
Identities = 175/344 (50%), Positives = 236/344 (68%), Gaps = 10/344 (2%)
Query: 120 GGFGGGGFG-------GGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNY 172
GG GG G +G G G L GNEK+ MQNLNDRLASYL+KVR LE+SN
Sbjct: 37 GGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNS 96
Query: 173 ELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAAD 232
+LE +IK+WYE + RDYS YY+ I++L++QI + NA +LQIDNA+LAA+
Sbjct: 97 KLEVQIKQWYETNAPR---AGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAE 153
Query: 233 DFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMK 292
DFRLKYE E +R +VEAD+ GL +V D+LTL K DLE+QIE L ++LA LKK H+EE+
Sbjct: 154 DFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVD 213
Query: 293 DLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEID 352
L VNVE++AAPG++L ++N MR +YE +A++N ++A+ F ++ L ++
Sbjct: 214 GLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVT 273
Query: 353 NNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQIS 412
N E++ + ++TELRR Q+LEIELQS L++K+SLE +L ET+ RY QL+ +Q+ +S
Sbjct: 274 VNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLS 333
Query: 413 ALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGE 456
+LE QL QIR+ E QN EY LLDIK RLE EI TYR LLEGE
Sbjct: 334 SLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGE 377
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 324 bits (831), Expect = 1e-88
Identities = 182/385 (47%), Positives = 255/385 (66%), Gaps = 10/385 (2%)
Query: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGG 130
S Y LG S+ G+ SS Y G+ G GS S + GG G GG G
Sbjct: 10 STNYRSLGSVQAPSY-GARPVSSAASVYAGAGGSGS--RISVSRSTSFRGGMGSGGLATG 66
Query: 131 FGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQ 190
GG G GG+ NEK TMQ+LNDRLASYLD+VR+LE N LE KI+E EK G
Sbjct: 67 IAGGLAGMGGIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP--- 121
Query: 191 GEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEA 250
+ RD+S Y+K I+DL+ QI T DNA I+LQIDNARLAADDFR+KYE E+A+RQSVE
Sbjct: 122 -QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
Query: 251 DINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLR-NVSTGDVNVEMNAA 309
DI+GLR+V+D+ +T+ LE +IE+L EEL ++KKNHEEE+K L+ +++ + VE++A
Sbjct: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
Query: 310 PGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELR 369
DL +++ ++R+QY++LA +NR++ + +++++ +E TT + ++ + ++ +TELR
Sbjct: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
Query: 370 RNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQN 429
R VQ+LEI+L S LK SLE SL E E RY +Q+ Q+ + LE +L Q RAE + Q
Sbjct: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360
Query: 430 TEYQQLLDIKIRLENEIQTYRSLLE 454
EY+ LL+IK++LE EI TYR LLE
Sbjct: 361 QEYEALLNIKVKLEAEIATYRRLLE 385
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 324 bits (831), Expect = 1e-88
Identities = 182/385 (47%), Positives = 255/385 (66%), Gaps = 10/385 (2%)
Query: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGG 130
S Y LG S+ G+ SS Y G+ G GS S + GG G GG G
Sbjct: 10 STNYRSLGSVQAPSY-GARPVSSAASVYAGAGGSGS--RISVSRSTSFRGGMGSGGLATG 66
Query: 131 FGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQ 190
GG G GG+ NEK TMQ+LNDRLASYLD+VR+LE N LE KI+E EK G
Sbjct: 67 IAGGLAGMGGIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP--- 121
Query: 191 GEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEA 250
+ RD+S Y+K I+DL+ QI T DNA I+LQIDNARLAADDFR+KYE E+A+RQSVE
Sbjct: 122 -QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
Query: 251 DINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLR-NVSTGDVNVEMNAA 309
DI+GLR+V+D+ +T+ LE +IE+L EEL ++KKNHEEE+K L+ +++ + VE++A
Sbjct: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
Query: 310 PGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELR 369
DL +++ ++R+QY++LA +NR++ + +++++ +E TT + ++ + ++ +TELR
Sbjct: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
Query: 370 RNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQN 429
R VQ+LEI+L S LK SLE SL E E RY +Q+ Q+ + LE +L Q RAE + Q
Sbjct: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360
Query: 430 TEYQQLLDIKIRLENEIQTYRSLLE 454
EY+ LL+IK++LE EI TYR LLE
Sbjct: 361 QEYEALLNIKVKLEAEIATYRRLLE 385
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 318 bits (815), Expect = 9e-87
Identities = 174/320 (54%), Positives = 226/320 (70%), Gaps = 9/320 (2%)
Query: 140 GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPR---DY 196
G +G+EK TMQ LNDRLASYL+KVR LE N ELE I+E S Q EP Y
Sbjct: 92 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQE------RSQQQEPLLCPSY 145
Query: 197 SKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLR 256
Y+KTI++L+ +IL +NA +++ IDNA+LA+DDFR KY+ E +LR VE+DIN +R
Sbjct: 146 QSYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIR 205
Query: 257 RVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQ 316
R+LDELTL K+DLE Q+ESL EEL LKKNHEEE+ LR+ +NVE++ AP VDL Q
Sbjct: 206 RILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQ 265
Query: 317 LLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALE 376
+LN RSQYE L E NR++ E WF +++EL ++ ++ EQ+ S ++EI ELRR V ALE
Sbjct: 266 VLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALE 325
Query: 377 IELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLL 436
IELQ+Q L+ SLE +L E+E Y QLSQ+Q+ I+ +E QL +IR + E QN EYQ LL
Sbjct: 326 IELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLL 385
Query: 437 DIKIRLENEIQTYRSLLEGE 456
D++ RLE EI TYRSLLE E
Sbjct: 386 DVRARLECEINTYRSLLESE 405
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 298 bits (762), Expect = 1e-80
Identities = 212/635 (33%), Positives = 318/635 (50%), Gaps = 76/635 (11%)
Query: 13 SSRSGGGGGGGGCGGGGGVS-SLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS- 70
+S++ GGG G G VS S R+S S G G + GF G+ GS GG+
Sbjct: 5 ASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNK 64
Query: 71 ------SGGYGGLGGFGGG----SFRGSYGS---SSFGGSYGGSFGGGSFGGGSFGG-GS 116
+ G GGFGGG +F G YG S +GG +GG FGGG GG FGG G
Sbjct: 65 SISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGG 124
Query: 117 FGG-GGFGG-GGFGG--GFGG--GFGGDGGL----------------------------- 141
FGG GGFGG GGFGG GFGG GFGG G L
Sbjct: 125 FGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLN 184
Query: 142 ---------LSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGE 192
+ E+ ++ LN++ AS++DKVR LE+ N LE K ++ +S G
Sbjct: 185 VEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGT 244
Query: 193 PRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADI 252
+ I+ L++ + N+ + + ++ N +DF+ KYE+E+ R + E +
Sbjct: 245 NNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEF 304
Query: 253 NGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRN-VSTGDVNVEMNAAPG 311
L++ +D + K +L+ ++++L +E+ +L+ ++ E+ +++ +S V + M+
Sbjct: 305 VTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRS 364
Query: 312 VDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRN 371
+DL ++ +R+QYE +A++++ +AEA + K EL T + + + + KSEI EL R
Sbjct: 365 LDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRM 424
Query: 372 VQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTE 431
+Q L E++ +L+ ++AE E + L A++ L+ LQQ + + +
Sbjct: 425 IQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRD 484
Query: 432 YQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGH 491
YQ+L+++K+ L+ EI TYR LLEGE G SS +S GG+GGG+
Sbjct: 485 YQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVS--SSTTSASAGGYGGGY 542
Query: 492 GGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGG- 550
GG GGG GGG S GG SG G+G G GG GG+GGGSSG GG G GS G
Sbjct: 543 GGGMGGGLGGGFSAGGGSGSGFGRGG-----GGGIGGGFGGGSSG-FSGGSGFGSISGAR 596
Query: 551 -SSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584
SGGG+ S+ GG S +SS RY
Sbjct: 597 YGVSGGGFSSASNRGG-----SIKFSQSSQSSQRY 626
Score = 296 bits (757), Expect = 5e-80
Identities = 206/602 (34%), Positives = 304/602 (50%), Gaps = 71/602 (11%)
Query: 7 SSKHYSSSRSGGGGGGG-----GCGGGGGVSSLRISSSKGS----LGGGFSSGGFSGGSF 57
SS+ + SGG GGG G GG G S + +K GG +GGF GG
Sbjct: 26 SSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRS 85
Query: 58 S---RGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG-GSFG 113
S G GGG G GG+GG GFGGG RG G FGG+ GG G G FGG G FG
Sbjct: 86 SCAFAGGYGGGFGSGYGGGFGG--GFGGG--RGMGGG--FGGA-GGFGGAGGFGGAGGFG 138
Query: 114 G-GSFGG-GGFGG-------GGFG-GGFGGG-----------------FGGDGGLLSGNE 146
G G FGG GGFGG GGFG GGF GG G + E
Sbjct: 139 GPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQE 198
Query: 147 KVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDL 206
+ ++ LN++ AS++DKVR LE+ N LE K ++ +S G + I+ L
Sbjct: 199 REQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYL 258
Query: 207 KNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTK 266
++ + N+ + + ++ N +DF+ KYE+E+ R + E + L++ +D + K
Sbjct: 259 RSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNK 318
Query: 267 ADLEMQIESLTEELAYLKKNHEEEMKDLR-NVSTGDVNVEMNAAPGVDLTQLLNNMRSQY 325
+L+ ++++L +E+ +L+ ++ E+ ++ ++S V + M+ +DL ++ +R+QY
Sbjct: 319 VELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRAQY 378
Query: 326 EQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLAL 385
E +A++++ +AEA + K EL T + + + + KSEI EL R +Q L E++
Sbjct: 379 EDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVKKQ 438
Query: 386 KQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENE 445
+L+ ++AE E + L A++ L+ LQQ + + +YQ+L+++K+ L+ E
Sbjct: 439 NANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALDVE 498
Query: 446 IQTYRSLLEGEG----------------SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGG 489
I TYR LLEGE SS G +GGGYGGG GGG GG
Sbjct: 499 IATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGG------MGGGLGG 552
Query: 490 GHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGG 549
G G G G G GGG GGG+GGG SSG GGS G G G GGG+ S+ G
Sbjct: 553 GFSAGGGSGSGFGRGGGGGIGGGFGGG-SSGFSGGSGFGSISGARYGVSGGGFSSASNRG 611
Query: 550 GS 551
GS
Sbjct: 612 GS 613
Score = 73.9 bits (180), Expect = 4e-13
Identities = 51/111 (45%), Positives = 57/111 (51%), Gaps = 18/111 (16%)
Query: 1 MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRG 60
+S+ SS S+S G GGG GG GGG LGGGFS+GG SG F RG
Sbjct: 521 VSISVVSSSTTSASAGGYGGGYGGGMGGG-------------LGGGFSAGGGSGSGFGRG 567
Query: 61 SSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGS 111
GGG GG G GG GF GGS GS + +G S GG F S GGS
Sbjct: 568 --GGGGIGGGFG--GGSSGFSGGSGFGSISGARYGVS-GGGFSSASNRGGS 613
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 296 bits (757), Expect = 5e-80
Identities = 218/623 (34%), Positives = 316/623 (50%), Gaps = 57/623 (9%)
Query: 6 SSSKHYSSSRSGGGGGGGGCG-----GGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRG 60
S S S GG GGG CG G G SL S S+ ++G G F G
Sbjct: 25 SGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGG 84
Query: 61 SSGGGCFGGSSGGYGGL--GGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG-GSFGG-GS 116
S G GG GG+GG GGFGGG GS FGG+ GG G G FGG G FGG GS
Sbjct: 85 RSSCGFAGGYGGGFGGSYGGGFGGGRGVGS----GFGGA-GGFGGAGGFGGPGVFGGPGS 139
Query: 117 FGG-GGFGGGGFGGGFGGGFGGDG-------------GLLSGNEKVTMQNLNDRLASYLD 162
FGG GGFG GGF GG G + E+ ++ LN++ AS++D
Sbjct: 140 FGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFID 199
Query: 163 KVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKT-IDDLKNQILNLTTDNANIL 221
KVR LE+ N LE K W + P +++ I L Q+ +L + N+
Sbjct: 200 KVRFLEQQNKVLETK---WELLQQQTTGSGPSSLEPCFESYISFLCKQLDSLLGERGNLE 256
Query: 222 LQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELA 281
++ + + +DF+ KYE+E+ R + E + GL++ +D + K +L+ +++SLT+E++
Sbjct: 257 GELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVELQAKVDSLTDEVS 316
Query: 282 YLKKNHEEEMKDLRN-VSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWF 340
+L+ +E E+ +++ S V + M+ +DL ++ +R+QYE++A++++ +AEA +
Sbjct: 317 FLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEIAQRSKSEAEALY 376
Query: 341 NEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRY 400
K EL T + + + + KSEI EL R +Q L E+++ +L+ ++AE E R
Sbjct: 377 QTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNANLQTAIAEAEQRG 436
Query: 401 CVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSG 460
+ L A++ L+ LQ+ + + +YQ+L+++K+ L+ EI TYR LLEGE
Sbjct: 437 EMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM 496
Query: 461 GGGRGGGSFGGGYGGGSSGGGSSGGGHG--GGHGGSSGGGYGGGSSGGGSSGGGYGGGSS 518
G +S GSSG G GG GS GGY GGSS SSG G GGS
Sbjct: 497 SGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSG 556
Query: 519 SGGHGGSSSGGYGG-GSSG-----------GGGGGYGGGSSGGGSSS-------GGGY-- 557
S G+GG SSG GG GSSG GG G SG GSSS G GY
Sbjct: 557 S-GYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKS 615
Query: 558 GGGSSSGGHKSSSSGSVGESSSK 580
GGG S+ S ++ S SS+K
Sbjct: 616 GGGGSTSIRFSQTTSSSQHSSTK 638
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/121 (39%), Positives = 54/121 (44%), Gaps = 9/121 (7%)
Query: 462 GGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGG 521
GG GGG+ G G GS G S + G S GSS G GGG +GG
Sbjct: 37 GGAGGGACGFRSGAGSFGSRSL---YNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGG 93
Query: 522 HGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581
+GG G YGGG GG G G G G + GG GG+GG GG GS G G
Sbjct: 94 YGGGFGGSYGGGFGGGRGVGSGFGGA-GGFGGAGGFGGPGVFGG-----PGSFGGPGGFG 147
Query: 582 P 582
P
Sbjct: 148 P 148
Score = 64.3 bits (155), Expect = 3e-10
Identities = 50/126 (39%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query: 468 SFGG---GYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGG--YGGGSS---- 518
SF G G+ G S+ S G +GGG G SG GS G Y GS+
Sbjct: 9 SFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSIS 68
Query: 519 -SGGHGGSSSGGYGGG-SSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGE 576
S G S +GG+GGG SS G GGYGGG G S GGG+GGG G + G G
Sbjct: 69 ISVAAGSSRAGGFGGGRSSCGFAGGYGGGF---GGSYGGGFGGGRGVGSGFGGAGGFGGA 125
Query: 577 SSSKGP 582
GP
Sbjct: 126 GGFGGP 131
Score = 58.9 bits (141), Expect = 1e-08
Identities = 49/135 (36%), Positives = 54/135 (40%), Gaps = 29/135 (21%)
Query: 2 SVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGS 61
+V +S SS GG G G G G+ GGS S S
Sbjct: 511 NVTSTSGSSGSSRGVFGGVSGSGSG------------------------GYKGGSSSSSS 546
Query: 62 SGGGCFGGSSGGYGGL--GGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGG 119
SG G GGS GYGG+ G GG GSY SSS G GG+ GS G GS G
Sbjct: 547 SGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGA---GSISVSHSGMGSSSG 603
Query: 120 GGFGGGGFGGGFGGG 134
GG G GGG
Sbjct: 604 SIQTSGGSGYKSGGG 618
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 295 bits (754), Expect = 1e-79
Identities = 160/324 (49%), Positives = 222/324 (68%), Gaps = 9/324 (2%)
Query: 138 DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPR--- 194
+ G+ + NEK TMQ LNDRLASYL+KVR+LEE+N ELE +I+E E Q P
Sbjct: 81 EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCE------QDIPMVCP 134
Query: 195 DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADING 254
DY +Y+ TI+DL+ +IL +N+ + +Q+DN +LA DDF+ KYE+E++LRQ +EADI+
Sbjct: 135 DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISS 194
Query: 255 LRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDL 314
L +L+ELTL K+DLE +ESL E+L LKKNHEEE+ LR ++VE++ AP +DL
Sbjct: 195 LHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDL 254
Query: 315 TQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQA 374
++L+ MR Q E + NR++AE W +++EL + ++ EQ+ + EI EL+R A
Sbjct: 255 NRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASA 314
Query: 375 LEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQ 434
LEIELQ+Q +L +SLE ++AETE +Y QL+QIQ I LE QL +IR + E QN EYQ
Sbjct: 315 LEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQV 374
Query: 435 LLDIKIRLENEIQTYRSLLEGEGS 458
LLD+K RLE EI TY LL+ E S
Sbjct: 375 LLDVKARLEGEINTYWGLLDSEDS 398
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.134 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,411,150
Number of Sequences: 37866
Number of extensions: 1778343
Number of successful extensions: 118964
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1015
Number of HSP's successfully gapped in prelim test: 767
Number of HSP's that attempted gapping in prelim test: 16596
Number of HSP's gapped (non-prelim): 38901
length of query: 584
length of database: 18,247,518
effective HSP length: 108
effective length of query: 476
effective length of database: 14,157,990
effective search space: 6739203240
effective search space used: 6739203240
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.