Guide to the Human Genome
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Search of human proteins with 194018748

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194018748 CD6 molecule [Homo sapiens]
         (668 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194018748 CD6 molecule [Homo sapiens]                             1402   0.0  
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...   255   1e-67
gi|148539842 deleted in malignant brain tumors 1 isoform b precu...   250   3e-66
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]     247   3e-65
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...   244   2e-64
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]     241   2e-63
gi|44889963 CD163 antigen isoform b [Homo sapiens]                    201   1e-51
gi|44662834 CD163 antigen isoform a [Homo sapiens]                    201   1e-51
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H...   199   7e-51
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]           192   1e-48
gi|5174411 CD5 molecule-like [Homo sapiens]                           191   2e-48
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]            179   6e-45
gi|18152779 scavenger receptor cysteine rich domain containing, ...   174   2e-43
gi|4506143 neurotrypsin precursor [Homo sapiens]                      170   3e-42
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]             135   1e-31
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]             134   3e-31
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]              130   3e-30
gi|5031863 galectin 3 binding protein [Homo sapiens]                  102   1e-21
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]              89   1e-17
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo...    86   8e-17
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]        84   4e-16
gi|5803080 macrophage receptor with collagenous structure [Homo ...    75   3e-13
gi|166197668 CD5 molecule [Homo sapiens]                               62   2e-09
gi|56117844 synovial sarcoma translocation, chromosome 18 isofor...    42   0.001
gi|223942069 enterokinase precursor [Homo sapiens]                     42   0.002
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     42   0.002
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     42   0.002
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       41   0.004
gi|47132519 Ras association and pleckstrin homology domains 1 is...    40   0.009
gi|15529996 son of sevenless homolog 1 [Homo sapiens]                  39   0.012

>gi|194018748 CD6 molecule [Homo sapiens]
          Length = 668

 Score = 1402 bits (3628), Expect = 0.0
 Identities = 668/668 (100%), Positives = 668/668 (100%)

Query: 1   MWLFFGITGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEV 60
           MWLFFGITGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEV
Sbjct: 1   MWLFFGITGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEV 60

Query: 61  RLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANAT 120
           RLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANAT
Sbjct: 61  RLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANAT 120

Query: 121 LAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHG 180
           LAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHG
Sbjct: 121 LAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHG 180

Query: 181 EWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC 240
           EWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC
Sbjct: 181 EWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC 240

Query: 241 PGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK 300
           PGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK
Sbjct: 241 PGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK 300

Query: 301 VLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360
           VLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC
Sbjct: 301 VLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360

Query: 361 SASRSLHNLSTPEVPASVQTVTIESSVTVKIENKESRELMLLIPSIVLGILLLGSLIFIA 420
           SASRSLHNLSTPEVPASVQTVTIESSVTVKIENKESRELMLLIPSIVLGILLLGSLIFIA
Sbjct: 361 SASRSLHNLSTPEVPASVQTVTIESSVTVKIENKESRELMLLIPSIVLGILLLGSLIFIA 420

Query: 421 FILLRIKGKYALPVMVNHQHLPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPPPEDSDS 480
           FILLRIKGKYALPVMVNHQHLPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPPPEDSDS
Sbjct: 421 FILLRIKGKYALPVMVNHQHLPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPPPEDSDS 480

Query: 481 GSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTA 540
           GSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTA
Sbjct: 481 GSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTA 540

Query: 541 NPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPWNPQVFSSERSSFLEQPP 600
           NPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPWNPQVFSSERSSFLEQPP
Sbjct: 541 NPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPWNPQVFSSERSSFLEQPP 600

Query: 601 NLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDND 660
           NLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDND
Sbjct: 601 NLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDND 660

Query: 661 DYDDISAA 668
           DYDDISAA
Sbjct: 661 DYDDISAA 668


>gi|148539844 deleted in malignant brain tumors 1 isoform c
           precursor [Homo sapiens]
          Length = 2403

 Score =  255 bits (651), Expect = 1e-67
 Identities = 165/423 (39%), Positives = 209/423 (49%), Gaps = 55/423 (13%)

Query: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
           G++ +A    P+P+P D   TS A +    P   L +RL NG   C G VEV    SW  
Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 386

Query: 69  ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
            C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 431

Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAE----------------NRALRLVDGG 167
           CSG E  L        + H C+     A V C++                + ALRLV+GG
Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSDTLPTITLPASTVGSESSLALRLVNGG 490

Query: 168 GACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQ 227
             C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D 
Sbjct: 491 DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDD 550

Query: 228 VNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS---WRLTGGADRCEGQVEVHFR 283
           V CSG E+YLW CP      H CGH EDAG +CS  +S    RL  G DRC+G+VEV +R
Sbjct: 551 VRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYR 610

Query: 284 GVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSN 339
           G W TVCD  W  ++A V+C+ LGCG A   P        SG +      C+G E  L +
Sbjct: 611 GSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 670

Query: 340 CSWRFNNSNLCSQSLAARVLCSASRSL-----HNLSTPEVPASVQTVTIESSVTVKIENK 394
           C      S+ C     A V+CSA++S        LST  +P S  TV  ESS+T+++ N 
Sbjct: 671 CPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPS--TVGSESSLTLRLVNG 728

Query: 395 ESR 397
             R
Sbjct: 729 SDR 731



 Score =  243 bits (619), Expect = 5e-64
 Identities = 163/450 (36%), Positives = 204/450 (45%), Gaps = 80/450 (17%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +     P+P+P D   TS A +    P   L +RL NG   C G VEV    SW  
Sbjct: 819  GVICSVSQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 875

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 876  VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 920

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157
            CSG E  L        + H C+     A V C+                           
Sbjct: 921  CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 979

Query: 158  NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217
            + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F 
Sbjct: 980  SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 1039

Query: 218  PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W--- 265
             G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W   
Sbjct: 1040 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 1099

Query: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312
                         RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 1100 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 1159

Query: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368
              P        SG +      C+G E  L +C      S+ C     A V+CSAS+S   
Sbjct: 1160 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1219

Query: 369  LSTPEVPAS-VQTVTIESSVTVKIENKESR 397
             S    P S   T   ESS+ +++ N   R
Sbjct: 1220 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1249



 Score =  241 bits (615), Expect = 2e-63
 Identities = 160/450 (35%), Positives = 201/450 (44%), Gaps = 78/450 (17%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A     +P P D L+T +           L +RL NGS  C G VEV    SW  
Sbjct: 688  GVICSAAQSRSTPRP-DTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGT 746

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +               A GN      +       + 
Sbjct: 747  VCDDSWDTNDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 791

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 792  CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSL 850

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 851  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 910

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSW------------- 265
             GPI  D V CSG E+YLW CP      H C H EDAG +CS   SW             
Sbjct: 911  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 970

Query: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312
                         RL  G DRC+G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 971  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1030

Query: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368
              P        SG +      C+G E  L +C      S+ C  S  A V+CSAS+S   
Sbjct: 1031 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1090

Query: 369  LSTPEVPAS-VQTVTIESSVTVKIENKESR 397
             S    P S   T   ESS+ +++ N   R
Sbjct: 1091 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1120



 Score =  239 bits (611), Expect = 5e-63
 Identities = 163/448 (36%), Positives = 202/448 (45%), Gaps = 78/448 (17%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 1079 GVICSASQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1135

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 1136 VCDDYWDTNDANVVCRQLGCGWAMSAP---------------GNARFGQGSGPIVLDDVR 1180

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 1181 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1239

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 1240 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1299

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 1300 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1359

Query: 266  -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314
                       RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A   
Sbjct: 1360 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1419

Query: 315  PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370
            P        SG +      C+G E  L +C      S+ C     A V+CSAS+S    S
Sbjct: 1420 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1479

Query: 371  TPEVPAS-VQTVTIESSVTVKIENKESR 397
                P S   T   ES++ +++ N   R
Sbjct: 1480 PDTWPTSRASTAGSESTLALRLVNGGDR 1507



 Score =  238 bits (606), Expect = 2e-62
 Identities = 155/411 (37%), Positives = 197/411 (47%), Gaps = 57/411 (13%)

Query: 39  PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA---- 94
           P   L +RL NG   C G VEV    SW   C   WD+  A  VCR LGCG A +A    
Sbjct: 586 PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 645

Query: 95  --SQLAPPTPELPPPPAAGNTS----------VAANATLAGAPALLCSGAEWRLCEVVEH 142
              Q + P   L     +G+ S          ++ N        ++CS A+ R     + 
Sbjct: 646 RFGQGSGPIV-LDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT 704

Query: 143 ACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202
                   + V    +  LRLV+G   C GRVE+L  G WG+VCDD+WD  DA+VVCRQL
Sbjct: 705 LSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 764

Query: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSE 261
           GCGWA  A     F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS 
Sbjct: 765 GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 824

Query: 262 HQS--------W----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPS 297
            QS        W                RL  G DRC+G+VEV +RG W TVCD  W  S
Sbjct: 825 SQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 884

Query: 298 EAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQS 353
           +A V+C+ LGCG A   P        SG +      C+G E  L +C      S+ C  S
Sbjct: 885 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 944

Query: 354 LAARVLCSASRSLHNLSTPEVPASVQTVTI-------ESSVTVKIENKESR 397
             A V+CSA+   H+ STP  P ++ T+T+       ESS+ +++ N   R
Sbjct: 945 EDAGVICSAA---HSWSTPS-PDTLPTITLPASTVGSESSLALRLVNGGDR 991



 Score =  235 bits (600), Expect = 9e-62
 Identities = 163/452 (36%), Positives = 204/452 (45%), Gaps = 84/452 (18%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 1208 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1264

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 1265 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1309

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 1310 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1368

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 1369 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1428

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 1429 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 1488

Query: 266  -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314
                       RL  G DRC G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+  
Sbjct: 1489 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1548

Query: 315  PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL---- 366
            P        SG +      C+G E  L +C      S+ C     A V+CSA++S     
Sbjct: 1549 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1608

Query: 367  -HNLSTPEVPASVQTVTIESSVTVKIENKESR 397
                 T  +PA   TV  ESS+ +++ N   R
Sbjct: 1609 PDTWLTTNLPA--LTVGSESSLALRLVNGGDR 1638



 Score =  234 bits (598), Expect = 1e-61
 Identities = 160/430 (37%), Positives = 195/430 (45%), Gaps = 85/430 (19%)

Query: 30  SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88
           S+ ES + E  +  L +RL NG   C G VE+    SW   C   WD+  A  VCR LGC
Sbjct: 86  STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145

Query: 89  GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143
           G A +               A GN      +       + CSG E  L        + H 
Sbjct: 146 GWAMS---------------APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190

Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176
           C   G  A V C+                            + ALRLV+GG  C GRVE+
Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249

Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236
           L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG E+Y
Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309

Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271
           LW CP      H CGH EDAG +CS  QS        W                RL  G 
Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 369

Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329
           DRC+G+VEV +RG W TVCD  W  S+A V+C+ LGCG A   P        SG +    
Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429

Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSV 387
             C+G E  L +C      S+ C  S  A V+CS       L T  +PAS  TV  ESS+
Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS-----DTLPTITLPAS--TVGSESSL 482

Query: 388 TVKIENKESR 397
            +++ N   R
Sbjct: 483 ALRLVNGGDR 492



 Score =  232 bits (591), Expect = 1e-60
 Identities = 152/416 (36%), Positives = 190/416 (45%), Gaps = 79/416 (18%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 1337 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1393

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 1394 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1438

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 1439 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTL 1497

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G
Sbjct: 1498 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 1557

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 1558 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1617

Query: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312
                         RL  G DRC G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 1618 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1677

Query: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364
              P        SG +      C+G E  L +C  +   ++ C     A V+CSA++
Sbjct: 1678 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1733



 Score =  200 bits (508), Expect = 4e-51
 Identities = 133/344 (38%), Positives = 164/344 (47%), Gaps = 44/344 (12%)

Query: 95  SQLAPPTPELPPPPAAGNT----SVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR 150
           + L P    L P  A G+     S   +    G+P  L S  E     V E +       
Sbjct: 31  ASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLE---STVAEGSLIPSEST 87

Query: 151 ARVTCAENR----ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206
              T AE      ALRLV+G G C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGW
Sbjct: 88  LESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGW 147

Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ-- 263
           A+ A     F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  Q  
Sbjct: 148 AMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQ 207

Query: 264 ------SW-------------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298
                 SW                   RL  G DRC G+VEV +RG W TVCD  W  ++
Sbjct: 208 STLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTND 267

Query: 299 AKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSL 354
           A V+C+ LGCG A+  P        SG +      C+G E  L +C      ++ C  S 
Sbjct: 268 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSE 327

Query: 355 AARVLCSASRSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397
            A V+CSA +S    S    P S   T   ESS+ +++ N   R
Sbjct: 328 DAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR 371



 Score =  180 bits (456), Expect = 4e-45
 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 1466 GVICSASQSQPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 1522

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 1523 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 1581

Query: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172
              ++ N        ++CS A+ +     +    ++     V    + ALRLV+GG  C G
Sbjct: 1582 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1641

Query: 173  RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232
            RVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG
Sbjct: 1642 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1701

Query: 233  AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291
             E+YLW CP      H CGH EDAG +CS  Q                       N+   
Sbjct: 1702 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1739

Query: 292  SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342
              W+P+       S  CG  +    G   S S   YY  N      + C W
Sbjct: 1740 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1784



 Score =  117 bits (292), Expect = 4e-26
 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 159  RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
            R + L    G CAGRVE+   G WG+VCDD+W +++A VVCRQLGCG AV AL   +F  
Sbjct: 1874 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1933

Query: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260
            G GPI  D V CSG E+ LW C       H C H+EDAG +CS
Sbjct: 1934 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1976



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%)

Query: 274  CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328
            C G+VE++  G W TVCD  W   EA+V+C+ LGCG AV        S  G  Y+     
Sbjct: 1885 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1936

Query: 329  -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372
                    C+G E TL  C  R   S+ C+    A V+CS     ++LSTP
Sbjct: 1937 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1983



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 45   VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94
            +RL N +SS   C+G VE+    +W   C   W  + AE VCR LGCG A +A
Sbjct: 1873 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1925


>gi|148539842 deleted in malignant brain tumors 1 isoform b
           precursor [Homo sapiens]
          Length = 2413

 Score =  250 bits (639), Expect = 3e-66
 Identities = 165/433 (38%), Positives = 208/433 (48%), Gaps = 65/433 (15%)

Query: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
           G++ +A    P+P+P D   TS A +    P   L +RL NG   C G VEV    SW  
Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 386

Query: 69  ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
            C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 431

Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157
           CSG E  L        + H C+     A V C+                           
Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 490

Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217
           + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F 
Sbjct: 491 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG 550

Query: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS---WRLTGGADR 273
            G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  +S    RL  G DR
Sbjct: 551 QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDR 610

Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS--- 329
           C+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A   P        SG +      
Sbjct: 611 CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVR 670

Query: 330 CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLSTPEVPASVQTVTIE 384
           C+G E  L +C      S+ C     A V+CSA++S        LST  +P S  TV  E
Sbjct: 671 CSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPS--TVGSE 728

Query: 385 SSVTVKIENKESR 397
           SS+T+++ N   R
Sbjct: 729 SSLTLRLVNGSDR 741



 Score =  243 bits (619), Expect = 5e-64
 Identities = 163/450 (36%), Positives = 204/450 (45%), Gaps = 80/450 (17%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +     P+P+P D   TS A +    P   L +RL NG   C G VEV    SW  
Sbjct: 829  GVICSVSQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 885

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 886  VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 930

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157
            CSG E  L        + H C+     A V C+                           
Sbjct: 931  CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 989

Query: 158  NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217
            + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F 
Sbjct: 990  SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 1049

Query: 218  PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W--- 265
             G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W   
Sbjct: 1050 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 1109

Query: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312
                         RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 1110 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 1169

Query: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368
              P        SG +      C+G E  L +C      S+ C     A V+CSAS+S   
Sbjct: 1170 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1229

Query: 369  LSTPEVPAS-VQTVTIESSVTVKIENKESR 397
             S    P S   T   ESS+ +++ N   R
Sbjct: 1230 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1259



 Score =  241 bits (615), Expect = 2e-63
 Identities = 160/450 (35%), Positives = 201/450 (44%), Gaps = 78/450 (17%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A     +P P D L+T +           L +RL NGS  C G VEV    SW  
Sbjct: 698  GVICSAAQSRSTPRP-DTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGT 756

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +               A GN      +       + 
Sbjct: 757  VCDDSWDTNDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 801

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 802  CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSL 860

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 861  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 920

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSW------------- 265
             GPI  D V CSG E+YLW CP      H C H EDAG +CS   SW             
Sbjct: 921  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 980

Query: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312
                         RL  G DRC+G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 981  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1040

Query: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368
              P        SG +      C+G E  L +C      S+ C  S  A V+CSAS+S   
Sbjct: 1041 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100

Query: 369  LSTPEVPAS-VQTVTIESSVTVKIENKESR 397
             S    P S   T   ESS+ +++ N   R
Sbjct: 1101 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1130



 Score =  239 bits (611), Expect = 5e-63
 Identities = 163/448 (36%), Positives = 202/448 (45%), Gaps = 78/448 (17%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 1089 GVICSASQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1145

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 1146 VCDDYWDTNDANVVCRQLGCGWAMSAP---------------GNARFGQGSGPIVLDDVR 1190

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 1191 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1249

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 1250 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1309

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 1310 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1369

Query: 266  -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314
                       RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A   
Sbjct: 1370 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1429

Query: 315  PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370
            P        SG +      C+G E  L +C      S+ C     A V+CSAS+S    S
Sbjct: 1430 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1489

Query: 371  TPEVPAS-VQTVTIESSVTVKIENKESR 397
                P S   T   ES++ +++ N   R
Sbjct: 1490 PDTWPTSRASTAGSESTLALRLVNGGDR 1517



 Score =  238 bits (608), Expect = 1e-62
 Identities = 161/437 (36%), Positives = 201/437 (45%), Gaps = 89/437 (20%)

Query: 30  SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88
           S+ ES + E  +  L +RL NG   C G VE+    SW   C   WD+  A  VCR LGC
Sbjct: 86  STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145

Query: 89  GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143
           G A +A                GN      +       + CSG E  L        + H 
Sbjct: 146 GWAMSAP---------------GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190

Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176
           C   G  A V C+                            + ALRLV+GG  C GRVE+
Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249

Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236
           L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG E+Y
Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309

Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271
           LW CP      H CGH EDAG +CS  QS        W                RL  G 
Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 369

Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329
           DRC+G+VEV +RG W TVCD  W  S+A V+C+ LGCG A   P        SG +    
Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429

Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTI---- 383
             C+G E  L +C      S+ C  S  A V+CSA+   H+ STP  P ++ T+T+    
Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA---HSWSTPS-PDTLPTITLPAST 485

Query: 384 ---ESSVTVKIENKESR 397
              ESS+ +++ N   R
Sbjct: 486 VGSESSLALRLVNGGDR 502



 Score =  238 bits (606), Expect = 2e-62
 Identities = 155/411 (37%), Positives = 197/411 (47%), Gaps = 57/411 (13%)

Query: 39   PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA---- 94
            P   L +RL NG   C G VEV    SW   C   WD+  A  VCR LGCG A +A    
Sbjct: 596  PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 655

Query: 95   --SQLAPPTPELPPPPAAGNTS----------VAANATLAGAPALLCSGAEWRLCEVVEH 142
               Q + P   L     +G+ S          ++ N        ++CS A+ R     + 
Sbjct: 656  RFGQGSGPIV-LDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT 714

Query: 143  ACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202
                    + V    +  LRLV+G   C GRVE+L  G WG+VCDD+WD  DA+VVCRQL
Sbjct: 715  LSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 774

Query: 203  GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSE 261
            GCGWA  A     F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS 
Sbjct: 775  GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 834

Query: 262  HQS--------W----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPS 297
             QS        W                RL  G DRC+G+VEV +RG W TVCD  W  S
Sbjct: 835  SQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 894

Query: 298  EAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQS 353
            +A V+C+ LGCG A   P        SG +      C+G E  L +C      S+ C  S
Sbjct: 895  DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 954

Query: 354  LAARVLCSASRSLHNLSTPEVPASVQTVTI-------ESSVTVKIENKESR 397
              A V+CSA+   H+ STP  P ++ T+T+       ESS+ +++ N   R
Sbjct: 955  EDAGVICSAA---HSWSTPS-PDTLPTITLPASTVGSESSLALRLVNGGDR 1001



 Score =  235 bits (600), Expect = 9e-62
 Identities = 163/452 (36%), Positives = 204/452 (45%), Gaps = 84/452 (18%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 1218 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1274

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 1275 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1319

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 1320 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1378

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 1379 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1438

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 1439 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 1498

Query: 266  -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314
                       RL  G DRC G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+  
Sbjct: 1499 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1558

Query: 315  PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL---- 366
            P        SG +      C+G E  L +C      S+ C     A V+CSA++S     
Sbjct: 1559 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1618

Query: 367  -HNLSTPEVPASVQTVTIESSVTVKIENKESR 397
                 T  +PA   TV  ESS+ +++ N   R
Sbjct: 1619 PDTWLTTNLPA--LTVGSESSLALRLVNGGDR 1648



 Score =  232 bits (591), Expect = 1e-60
 Identities = 152/416 (36%), Positives = 190/416 (45%), Gaps = 79/416 (18%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 1347 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1403

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 1404 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1448

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 1449 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTL 1507

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G
Sbjct: 1508 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 1567

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 1568 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1627

Query: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312
                         RL  G DRC G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 1628 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1687

Query: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364
              P        SG +      C+G E  L +C  +   ++ C     A V+CSA++
Sbjct: 1688 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1743



 Score =  200 bits (508), Expect = 4e-51
 Identities = 133/344 (38%), Positives = 164/344 (47%), Gaps = 44/344 (12%)

Query: 95  SQLAPPTPELPPPPAAGNT----SVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR 150
           + L P    L P  A G+     S   +    G+P  L S  E     V E +       
Sbjct: 31  ASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLE---STVAEGSLIPSEST 87

Query: 151 ARVTCAENR----ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206
              T AE      ALRLV+G G C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGW
Sbjct: 88  LESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGW 147

Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ-- 263
           A+ A     F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  Q  
Sbjct: 148 AMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQ 207

Query: 264 ------SW-------------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298
                 SW                   RL  G DRC G+VEV +RG W TVCD  W  ++
Sbjct: 208 STLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTND 267

Query: 299 AKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSL 354
           A V+C+ LGCG A+  P        SG +      C+G E  L +C      ++ C  S 
Sbjct: 268 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSE 327

Query: 355 AARVLCSASRSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397
            A V+CSA +S    S    P S   T   ESS+ +++ N   R
Sbjct: 328 DAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR 371



 Score =  180 bits (456), Expect = 4e-45
 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 1476 GVICSASQSQPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 1532

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 1533 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 1591

Query: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172
              ++ N        ++CS A+ +     +    ++     V    + ALRLV+GG  C G
Sbjct: 1592 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1651

Query: 173  RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232
            RVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG
Sbjct: 1652 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1711

Query: 233  AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291
             E+YLW CP      H CGH EDAG +CS  Q                       N+   
Sbjct: 1712 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1749

Query: 292  SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342
              W+P+       S  CG  +    G   S S   YY  N      + C W
Sbjct: 1750 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1794



 Score =  117 bits (292), Expect = 4e-26
 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 159  RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
            R + L    G CAGRVE+   G WG+VCDD+W +++A VVCRQLGCG AV AL   +F  
Sbjct: 1884 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1943

Query: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260
            G GPI  D V CSG E+ LW C       H C H+EDAG +CS
Sbjct: 1944 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%)

Query: 274  CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328
            C G+VE++  G W TVCD  W   EA+V+C+ LGCG AV        S  G  Y+     
Sbjct: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1946

Query: 329  -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372
                    C+G E TL  C  R   S+ C+    A V+CS     ++LSTP
Sbjct: 1947 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1993



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 45   VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94
            +RL N +SS   C+G VE+    +W   C   W  + AE VCR LGCG A +A
Sbjct: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1935


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score =  247 bits (630), Expect = 3e-65
 Identities = 162/441 (36%), Positives = 208/441 (47%), Gaps = 59/441 (13%)

Query: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
           G++ +A     +P+P D L T +  +        L +RL NG   C G VEV    SW  
Sbjct: 459 GVICSAAHSWSTPSP-DTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517

Query: 69  ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPE---------LPPPPAAGNTS----- 114
            C   WD+  A  VCR LGCG A     LAP             L     +GN S     
Sbjct: 518 VCDDSWDTNDANVVCRQLGCGWA----MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSC 573

Query: 115 -----VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCA---ENRALRLVDG 166
                ++ N   +    ++CS  +W    +   +  S    A  TC     + ALRLV+G
Sbjct: 574 PHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSS--HALQTCKGPESSLALRLVNG 631

Query: 167 GGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRD 226
           G  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA  A     F  G GPI  D
Sbjct: 632 GDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD 691

Query: 227 QVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W------------ 265
            V CSG E+YLW CP      H CGH EDAG +CS  QS        W            
Sbjct: 692 DVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSES 751

Query: 266 ----RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHS 321
               RL  G DRC+G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+  P      
Sbjct: 752 SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 811

Query: 322 L-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPAS 377
             SG +      C+G E  L +C      S+ C  S  A V+CSAS+S    S    P S
Sbjct: 812 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 871

Query: 378 -VQTVTIESSVTVKIENKESR 397
              T   ES++ +++ N   R
Sbjct: 872 RASTAGSESTLALRLVNGGDR 892



 Score =  240 bits (613), Expect = 3e-63
 Identities = 162/439 (36%), Positives = 208/439 (47%), Gaps = 55/439 (12%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +AL   P+P  P    +S A      P   L +RL NG   C G VEV    SW  
Sbjct: 590  GVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGT 649

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 650  VCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPNN 708

Query: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172
              ++ N        ++CS A+ R     +    S    A      + ALRLV+GG  C G
Sbjct: 709  GWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAG--SESSLALRLVNGGDRCQG 766

Query: 173  RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232
            RVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG
Sbjct: 767  RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 826

Query: 233  AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RL 267
             E+YLW CP      H CGH EDAG +CS  QS        W                RL
Sbjct: 827  HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRL 886

Query: 268  TGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRM 326
              G DRC G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+  P        SG +
Sbjct: 887  VNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPI 946

Query: 327  YYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLSTPEVPASV 378
                  C+G E  L +C      S+ C     A V+CSA++S          T  +PA  
Sbjct: 947  VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPA-- 1004

Query: 379  QTVTIESSVTVKIENKESR 397
             TV  ESS+ +++ N   R
Sbjct: 1005 LTVGSESSLALRLVNGGDR 1023



 Score =  238 bits (608), Expect = 1e-62
 Identities = 161/437 (36%), Positives = 201/437 (45%), Gaps = 89/437 (20%)

Query: 30  SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88
           S+ ES + E  +  L +RL NG   C G VE+    SW   C   WD+  A  VCR LGC
Sbjct: 86  STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145

Query: 89  GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143
           G A +               A GN      +       + CSG E  L        + H 
Sbjct: 146 GWAMS---------------APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190

Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176
           C   G  A V C+                            + ALRLV+GG  C GRVE+
Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249

Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236
           L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG E+Y
Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309

Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271
           LW CP      H CGH EDAG +CS  QS        W                RL  G 
Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGG 369

Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329
           DRC+G+VEV +RG W TVCD  W  S+A V+C+ LGCG A   P        SG +    
Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429

Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTI---- 383
             C+G E  L +C      S+ C  S  A V+CSA+   H+ STP  P ++ T+T+    
Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA---HSWSTPS-PDTLPTITLPAST 485

Query: 384 ---ESSVTVKIENKESR 397
              ESS+ +++ N   R
Sbjct: 486 VGSESSLALRLVNGGDR 502



 Score =  236 bits (602), Expect = 5e-62
 Identities = 162/453 (35%), Positives = 203/453 (44%), Gaps = 83/453 (18%)

Query: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
           G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 386

Query: 69  ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
            C   WD+  A  VCR LGCG A +               A GN      +       + 
Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 431

Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157
           CSG E  L        + H C+     A V C+                           
Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQ-HSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 490

Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217
           + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F 
Sbjct: 491 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG 550

Query: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ---------SW-- 265
            G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  Q         SW  
Sbjct: 551 QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPS 610

Query: 266 ----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309
                           RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG
Sbjct: 611 SHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 670

Query: 310 TAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRS 365
            A   P        SG +      C+G E  L +C      S+ C     A V+CSA++S
Sbjct: 671 WATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQS 730

Query: 366 LHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397
                    P S   T   ESS+ +++ N   R
Sbjct: 731 RSTPRPDTWPTSHASTAGSESSLALRLVNGGDR 763



 Score =  229 bits (585), Expect = 5e-60
 Identities = 152/404 (37%), Positives = 197/404 (48%), Gaps = 55/404 (13%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A     +P P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 722  GVICSAAQSRSTPRP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYQGSWGT 778

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 779  VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPHN 837

Query: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENR-ALRLVDGGGACA 171
              ++ N   +    ++CS ++ R     +    S   RA    +E+  ALRLV+GG  C 
Sbjct: 838  GWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS---RASTAGSESTLALRLVNGGDRCR 894

Query: 172  GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231
            GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CS
Sbjct: 895  GRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCS 954

Query: 232  GAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------- 265
            G E+YLW CP      H CGH EDAG +CS  QS        W                 
Sbjct: 955  GHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLA 1014

Query: 266  -RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-S 323
             RL  G DRC G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+  P        S
Sbjct: 1015 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1074

Query: 324  GRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364
            G +      C+G E  L +C  +   ++ C     A V+CSA++
Sbjct: 1075 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1118



 Score =  228 bits (580), Expect = 2e-59
 Identities = 155/422 (36%), Positives = 188/422 (44%), Gaps = 86/422 (20%)

Query: 43  LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102
           L +RL NG   C G VEV    SW   C   WD+  A  VCR LGCG A +A        
Sbjct: 232 LALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP------- 284

Query: 103 ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHACRSDGRRARVTCA- 156
                   GN      +       + CSG E  L        + H C      A V C+ 
Sbjct: 285 --------GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNC-GHSEDAGVICSA 335

Query: 157 -----------------------ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLE 193
                                   + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  
Sbjct: 336 PQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395

Query: 194 DAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHK 252
           DA+VVCRQLGCGWA  A     F  G GPI  D V CSG E+YLW CP      H C H 
Sbjct: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455

Query: 253 EDAGAVCSEHQSW--------------------------RLTGGADRCEGQVEVHFRGVW 286
           EDAG +CS   SW                          RL  G DRC+G+VEV +RG W
Sbjct: 456 EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSW 515

Query: 287 NTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSW 342
            TVCD  W  ++A V+C+ LGCG A+  P        SG +      C+G E  L +C  
Sbjct: 516 GTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPH 575

Query: 343 RFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPAS------VQTVT-IESSVTVKIENKE 395
               S+ C  S  A V+CSA   L  L TP  P S      +QT    ESS+ +++ N  
Sbjct: 576 NGWLSHNCGHSEDAGVICSA---LQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGG 632

Query: 396 SR 397
            R
Sbjct: 633 DR 634



 Score =  180 bits (456), Expect = 4e-45
 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 851  GVICSASQSRPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 907

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 908  VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 966

Query: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172
              ++ N        ++CS A+ +     +    ++     V    + ALRLV+GG  C G
Sbjct: 967  GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1026

Query: 173  RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232
            RVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG
Sbjct: 1027 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1086

Query: 233  AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291
             E+YLW CP      H CGH EDAG +CS  Q                       N+   
Sbjct: 1087 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1124

Query: 292  SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342
              W+P+       S  CG  +    G   S S   YY  N      + C W
Sbjct: 1125 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1169



 Score =  117 bits (292), Expect = 4e-26
 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 159  RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
            R + L    G CAGRVE+   G WG+VCDD+W +++A VVCRQLGCG AV AL   +F  
Sbjct: 1259 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1318

Query: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260
            G GPI  D V CSG E+ LW C       H C H+EDAG +CS
Sbjct: 1319 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%)

Query: 274  CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328
            C G+VE++  G W TVCD  W   EA+V+C+ LGCG AV        S  G  Y+     
Sbjct: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1321

Query: 329  -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372
                    C+G E TL  C  R   S+ C+    A V+CS     ++LSTP
Sbjct: 1322 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1368



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 45   VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94
            +RL N +SS   C+G VE+    +W   C   W  + AE VCR LGCG A +A
Sbjct: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1310


>gi|148539840 deleted in malignant brain tumors 1 isoform a
           precursor [Homo sapiens]
          Length = 1785

 Score =  244 bits (622), Expect = 2e-64
 Identities = 164/450 (36%), Positives = 205/450 (45%), Gaps = 80/450 (17%)

Query: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
           G++ +A    P+P+P D   TS A +    P   L +RL NG   C G VEV    SW  
Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 386

Query: 69  ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
            C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 431

Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157
           CSG E  L        + H C+     A V C+                           
Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 490

Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217
           + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F 
Sbjct: 491 SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 550

Query: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W--- 265
            G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W   
Sbjct: 551 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 610

Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312
                        RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 611 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 670

Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368
             P        SG +      C+G E  L +C      S+ C     A V+CSAS+S   
Sbjct: 671 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 730

Query: 369 LSTPEVPAS-VQTVTIESSVTVKIENKESR 397
            S    P S   T   ESS+ +++ N   R
Sbjct: 731 PSPDTWPTSHASTAGSESSLALRLVNGGDR 760



 Score =  238 bits (608), Expect = 1e-62
 Identities = 161/437 (36%), Positives = 201/437 (45%), Gaps = 89/437 (20%)

Query: 30  SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88
           S+ ES + E  +  L +RL NG   C G VE+    SW   C   WD+  A  VCR LGC
Sbjct: 86  STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145

Query: 89  GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143
           G A +               A GN      +       + CSG E  L        + H 
Sbjct: 146 GWAMS---------------APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190

Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176
           C   G  A V C+                            + ALRLV+GG  C GRVE+
Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249

Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236
           L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG E+Y
Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309

Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271
           LW CP      H CGH EDAG +CS  QS        W                RL  G 
Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 369

Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329
           DRC+G+VEV +RG W TVCD  W  S+A V+C+ LGCG A   P        SG +    
Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429

Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTI---- 383
             C+G E  L +C      S+ C  S  A V+CSA+   H+ STP  P ++ T+T+    
Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA---HSWSTPS-PDTLPTITLPAST 485

Query: 384 ---ESSVTVKIENKESR 397
              ESS+ +++ N   R
Sbjct: 486 VGSESSLALRLVNGGDR 502



 Score =  235 bits (599), Expect = 1e-61
 Identities = 163/452 (36%), Positives = 204/452 (45%), Gaps = 84/452 (18%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 590  GVICSASQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 646

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 647  VCDDYWDTNDANVVCRQLGCGWAMSAP---------------GNARFGQGSGPIVLDDVR 691

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 692  CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 750

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 751  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 810

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 811  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 870

Query: 266  -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314
                       RL  G DRC G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+  
Sbjct: 871  STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 930

Query: 315  PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL---- 366
            P        SG +      C+G E  L +C      S+ C     A V+CSA++S     
Sbjct: 931  PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 990

Query: 367  -HNLSTPEVPASVQTVTIESSVTVKIENKESR 397
                 T  +PA   TV  ESS+ +++ N   R
Sbjct: 991  PDTWLTTNLPA--LTVGSESSLALRLVNGGDR 1020



 Score =  232 bits (591), Expect = 1e-60
 Identities = 152/416 (36%), Positives = 190/416 (45%), Gaps = 79/416 (18%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 719  GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 775

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 776  VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 820

Query: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 821  CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTL 879

Query: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G
Sbjct: 880  ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 939

Query: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 940  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 999

Query: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312
                         RL  G DRC G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 1000 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1059

Query: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364
              P        SG +      C+G E  L +C  +   ++ C     A V+CSA++
Sbjct: 1060 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1115



 Score =  200 bits (508), Expect = 4e-51
 Identities = 133/344 (38%), Positives = 164/344 (47%), Gaps = 44/344 (12%)

Query: 95  SQLAPPTPELPPPPAAGNT----SVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR 150
           + L P    L P  A G+     S   +    G+P  L S  E     V E +       
Sbjct: 31  ASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLE---STVAEGSLIPSEST 87

Query: 151 ARVTCAENR----ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206
              T AE      ALRLV+G G C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGW
Sbjct: 88  LESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGW 147

Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ-- 263
           A+ A     F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  Q  
Sbjct: 148 AMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQ 207

Query: 264 ------SW-------------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298
                 SW                   RL  G DRC G+VEV +RG W TVCD  W  ++
Sbjct: 208 STLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTND 267

Query: 299 AKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSL 354
           A V+C+ LGCG A+  P        SG +      C+G E  L +C      ++ C  S 
Sbjct: 268 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSE 327

Query: 355 AARVLCSASRSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397
            A V+CSA +S    S    P S   T   ESS+ +++ N   R
Sbjct: 328 DAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR 371



 Score =  180 bits (456), Expect = 4e-45
 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 848  GVICSASQSQPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 904

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 905  VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 963

Query: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172
              ++ N        ++CS A+ +     +    ++     V    + ALRLV+GG  C G
Sbjct: 964  GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1023

Query: 173  RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232
            RVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG
Sbjct: 1024 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1083

Query: 233  AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291
             E+YLW CP      H CGH EDAG +CS  Q                       N+   
Sbjct: 1084 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1121

Query: 292  SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342
              W+P+       S  CG  +    G   S S   YY  N      + C W
Sbjct: 1122 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1166



 Score =  117 bits (292), Expect = 4e-26
 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 159  RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
            R + L    G CAGRVE+   G WG+VCDD+W +++A VVCRQLGCG AV AL   +F  
Sbjct: 1256 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1315

Query: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260
            G GPI  D V CSG E+ LW C       H C H+EDAG +CS
Sbjct: 1316 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1358



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%)

Query: 274  CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328
            C G+VE++  G W TVCD  W   EA+V+C+ LGCG AV        S  G  Y+     
Sbjct: 1267 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1318

Query: 329  -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372
                    C+G E TL  C  R   S+ C+    A V+CS     ++LSTP
Sbjct: 1319 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1365



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 45   VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94
            +RL N +SS   C+G VE+    +W   C   W  + AE VCR LGCG A +A
Sbjct: 1255 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1307


>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score =  241 bits (615), Expect = 2e-63
 Identities = 165/455 (36%), Positives = 207/455 (45%), Gaps = 84/455 (18%)

Query: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
           G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 386

Query: 69  ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128
            C   WD+  A  VCR LGCG A +               A GN      +       + 
Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 431

Query: 129 CSGAEWRLCEV-----VEHACR------------------SDGRRAR------------- 152
           CSG E  L        + H C+                  S G R R             
Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPAST 491

Query: 153 VTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212
           V    + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A  
Sbjct: 492 VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPG 551

Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS------- 264
              F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS       
Sbjct: 552 NARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPD 611

Query: 265 -W----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLG 307
            W                RL  G DRC+G+VEV ++G W TVCD  W  ++A V+C+ LG
Sbjct: 612 TWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLG 671

Query: 308 CGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSAS 363
           CG A+  P        SG +      C+G E  L +C      S+ C  S  A V+CSAS
Sbjct: 672 CGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 731

Query: 364 RSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397
           +S    S    P S   T   ES++ +++ N   R
Sbjct: 732 QSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR 766



 Score =  235 bits (600), Expect = 9e-62
 Identities = 159/439 (36%), Positives = 195/439 (44%), Gaps = 87/439 (19%)

Query: 30  SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88
           S+ ES + E  +  L +RL NG   C G VE+    SW   C   WD+  A  VCR LGC
Sbjct: 86  STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145

Query: 89  GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143
           G A +A                GN      +       + CSG E  L        + H 
Sbjct: 146 GWAMSAP---------------GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190

Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176
           C   G  A V C+                            + ALRLV+GG  C GRVE+
Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249

Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236
           L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG E+Y
Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309

Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271
           LW CP      H CGH EDAG +CS  QS        W                RL  G 
Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGG 369

Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329
           DRC+G+VEV +RG W TVCD  W  S+A V+C+ LGCG A   P        SG +    
Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429

Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS---------TPEVPASV 378
             C+G E  L +C      S+ C  S  A V+CSA+ S    S          P +    
Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPA 489

Query: 379 QTVTIESSVTVKIENKESR 397
            TV  ESS+ +++ N   R
Sbjct: 490 STVGSESSLALRLVNGGDR 508



 Score =  235 bits (599), Expect = 1e-61
 Identities = 161/447 (36%), Positives = 207/447 (46%), Gaps = 66/447 (14%)

Query: 9   GLLTAALSGHPSPAP-----PDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLE 63
           G++ +A     +P+P      D L T +  +        L +RL NG   C G VEV   
Sbjct: 459 GVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYR 518

Query: 64  ASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPE---------LPPPPAAGNTS 114
            SW   C   WD+  A  VCR LGCG A     LAP             L     +GN S
Sbjct: 519 GSWGTVCDDSWDTNDANVVCRQLGCGWA----MLAPGNARFGQGSGPIVLDDVRCSGNES 574

Query: 115 ----------VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLV 164
                     ++ N   +    ++CS A+ R     +    S    A      + ALRLV
Sbjct: 575 YLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAG--SESSLALRLV 632

Query: 165 DGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIH 224
           +GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI 
Sbjct: 633 NGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 692

Query: 225 RDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W---------- 265
            D V CSG E+YLW CP      H CGH EDAG +CS  QS        W          
Sbjct: 693 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGS 752

Query: 266 ------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLP 319
                 RL  G DRC G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+  P    
Sbjct: 753 ESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQ 812

Query: 320 HSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLS 370
               SG +      C+G E  L +C      S+ C     A V+CSA++S          
Sbjct: 813 FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWL 872

Query: 371 TPEVPASVQTVTIESSVTVKIENKESR 397
           T  +PA   TV  ESS+ +++ N   R
Sbjct: 873 TTNLPA--LTVGSESSLALRLVNGGDR 897



 Score =  229 bits (585), Expect = 5e-60
 Identities = 152/404 (37%), Positives = 197/404 (48%), Gaps = 55/404 (13%)

Query: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
           G++ +A     +P P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 596 GVICSAAQSRSTPRP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYQGSWGT 652

Query: 69  ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114
            C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 653 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPHN 711

Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENR-ALRLVDGGGACA 171
             ++ N   +    ++CS ++ R     +    S   RA    +E+  ALRLV+GG  C 
Sbjct: 712 GWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS---RASTAGSESTLALRLVNGGDRCR 768

Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231
           GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CS
Sbjct: 769 GRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCS 828

Query: 232 GAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------- 265
           G E+YLW CP      H CGH EDAG +CS  QS        W                 
Sbjct: 829 GHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLA 888

Query: 266 -RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-S 323
            RL  G DRC G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+  P        S
Sbjct: 889 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 948

Query: 324 GRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364
           G +      C+G E  L +C  +   ++ C     A V+CSA++
Sbjct: 949 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 992



 Score =  180 bits (456), Expect = 4e-45
 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%)

Query: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 725  GVICSASQSRPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 781

Query: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 782  VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 840

Query: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172
              ++ N        ++CS A+ +     +    ++     V    + ALRLV+GG  C G
Sbjct: 841  GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 900

Query: 173  RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232
            RVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG
Sbjct: 901  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 960

Query: 233  AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291
             E+YLW CP      H CGH EDAG +CS  Q                       N+   
Sbjct: 961  NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 998

Query: 292  SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342
              W+P+       S  CG  +    G   S S   YY  N      + C W
Sbjct: 999  DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1043



 Score =  117 bits (292), Expect = 4e-26
 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 159  RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
            R + L    G CAGRVE+   G WG+VCDD+W +++A VVCRQLGCG AV AL   +F  
Sbjct: 1133 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1192

Query: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260
            G GPI  D V CSG E+ LW C       H C H+EDAG +CS
Sbjct: 1193 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%)

Query: 274  CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328
            C G+VE++  G W TVCD  W   EA+V+C+ LGCG AV        S  G  Y+     
Sbjct: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1195

Query: 329  -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372
                    C+G E TL  C  R   S+ C+    A V+CS     ++LSTP
Sbjct: 1196 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1242



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 45   VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94
            +RL N +SS   C+G VE+    +W   C   W  + AE VCR LGCG A +A
Sbjct: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1184


>gi|44889963 CD163 antigen isoform b [Homo sapiens]
          Length = 1121

 Score =  201 bits (512), Expect = 1e-51
 Identities = 122/358 (34%), Positives = 174/358 (48%), Gaps = 24/358 (6%)

Query: 40  GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99
           G  L +RL  G S C+GTVEV ++      C   W  + A+ VCR LGCG A   S    
Sbjct: 368 GSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSY--- 424

Query: 100 PTPELPPPPAAGNTSVAANATLAGAPALL-CSGAEWR--LCEVVEHACRSDGRRARVTCA 156
              ++     A NT +  ++      +L  C   +W    C+  E A        ++TC+
Sbjct: 425 ---QVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEA--------KITCS 473

Query: 157 ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216
            +R  RLV G   C+GRVE+     WGS+CD  + LE A V+CR+L CG  V  L G HF
Sbjct: 474 AHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHF 533

Query: 217 TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGADRCE 275
             G G I  ++  C G E++L  CP  P  +  C H  D G VCS +   RL  G   CE
Sbjct: 534 GEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCE 593

Query: 276 GQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSG----RMYYSCN 331
           G+VE+   G W ++C+S W   +A VLCQ L CG A+  P G           R  + C 
Sbjct: 594 GRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCT 653

Query: 332 GEELTLSNCSWRFNNSNLCSQSLAARVLCSA--SRSLHNLSTPEVPASVQTVTIESSV 387
           G E  + +C      ++LC     A V+CS   S++L + ++  +  +  T+  ES+V
Sbjct: 654 GTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAV 711



 Score =  200 bits (509), Expect = 3e-51
 Identities = 114/308 (37%), Positives = 157/308 (50%), Gaps = 32/308 (10%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGA---EAASQLAPPT 101
           +RL NG + C G VE++   +W   C + WD   A  +C+ L CG A      ++     
Sbjct: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642

Query: 102 PEL---------------PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRS 146
            ++                 P  A   S+  +  +A   +++CSG + +       +   
Sbjct: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVA---SVICSGNQSQTLSSCNSSSLG 699

Query: 147 DGR-----RARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQ 201
             R      + V C E+  LRLV+GGG CAGRVE+   G WG++CDD+WDL DAHVVCRQ
Sbjct: 700 PTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQ 759

Query: 202 LGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260
           LGCG A+ A    HF  G GPI  D++ C+G E+ +W C     GQ  C HKEDAG +CS
Sbjct: 760 LGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819

Query: 261 EHQSWRLTGGADR--CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGL 318
           E  S RLT  A R  C G++EV + G W TV  S    +   V+C+ LGC    ++ K  
Sbjct: 820 EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGC---ADKGKIN 876

Query: 319 PHSLSGRM 326
           P SL   M
Sbjct: 877 PASLDKAM 884



 Score =  198 bits (503), Expect = 2e-50
 Identities = 119/340 (35%), Positives = 170/340 (50%), Gaps = 32/340 (9%)

Query: 40  GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99
           G  L +RLT G + CSG +E++ +  W   C   ++   A  +CR L CG A + S    
Sbjct: 154 GSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFS---- 209

Query: 100 PTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVV-----EHACRSDGRRARVT 154
                      G+++    +       L+C+G E  L         +H C      A V 
Sbjct: 210 -----------GSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNC-DHAEDAGVI 257

Query: 155 CAENR--ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212
           C++    +LRLVDG   C+GR+E+   GEWG++CDD WD  DA V C+QLGC  AV A+ 
Sbjct: 258 CSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317

Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQ--SWRLTG 269
            ++ + G G I  D V+C G E  +W C     G+HYC H EDAG  CS+      RL G
Sbjct: 318 RVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRG 377

Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY- 328
           G  RC G VEV  + +   VCD  W   EA V+C+ LGCG+A++    +   +     + 
Sbjct: 378 GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437

Query: 329 ---SCNGEELTLSNC-SWRFNNSNLCSQSLAARVLCSASR 364
              SCNG E +L +C +W++     C     A++ CSA R
Sbjct: 438 FLSSCNGNETSLWDCKNWQWGGLT-CDHYEEAKITCSAHR 476



 Score =  194 bits (493), Expect = 2e-49
 Identities = 119/343 (34%), Positives = 163/343 (47%), Gaps = 43/343 (12%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
           +RL +G + CSG VEV+++  W   C   W   A   +C  LGC             P  
Sbjct: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGC-------------PTA 97

Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG----------RRARVT 154
              P   N+S  A +       + C G E  L +     C+ DG          + A VT
Sbjct: 98  IKAPGWANSS--AGSGRIWMDHVSCRGNESALWD-----CKHDGWGKHSNCTHQQDAGVT 150

Query: 155 CAE--NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212
           C++  N  +RL  GG  C+GR+E+   G WG+VCDD ++++ A V+CRQL CG AV    
Sbjct: 151 CSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSG 210

Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSE--HQSWRLTG 269
             +F  G GPI  D + C+G E+ LW+C     G+H C H EDAG +CS+    S RL  
Sbjct: 211 SSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVD 270

Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTA------VERPKGLPHSLS 323
           G   C G++EV F+G W T+CD  W   +A V C+ LGC TA      V   KG  H   
Sbjct: 271 GVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWL 330

Query: 324 GRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
             +  SC G E  +  C       + C+ +  A V CS    L
Sbjct: 331 DSV--SCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDL 371



 Score =  171 bits (432), Expect = 3e-42
 Identities = 116/371 (31%), Positives = 157/371 (42%), Gaps = 69/371 (18%)

Query: 46  RLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELP 105
           RL  G   CSG VEV+   +W   C + +   AA  +CR L CG   +            
Sbjct: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSI----------- 527

Query: 106 PPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVV---EHACRSDGRRARVTCAENRA 160
                G            A    C G E  L  C V    E  C S  R   V C+    
Sbjct: 528 ----LGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTC-SHSRDVGVVCSRYTE 582

Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220
           +RLV+G   C GRVE+   G WGS+C+  WD+EDAHV+C+QL CG A+    G  F  G 
Sbjct: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642

Query: 221 GPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQS--------------- 264
           G I R   +C+G E ++ DCP    G   C  ++ A  +CS +QS               
Sbjct: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR 702

Query: 265 ----------------WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC 308
                            RL  G  RC G+VE++  G W T+CD  W  S+A V+C+ LGC
Sbjct: 703 PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762

Query: 309 GTAVERPKGLPHSLSGR-----MYYSCNGEELTL----------SNCSWRFNNSNLCSQS 353
           G A+    G  H   G          CNG+E  +           NC  + +   +CS+ 
Sbjct: 763 GEAI-NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEF 821

Query: 354 LAARVLCSASR 364
           ++ R+   ASR
Sbjct: 822 MSLRLTSEASR 832



 Score =  154 bits (390), Expect = 2e-37
 Identities = 83/217 (38%), Positives = 118/217 (54%), Gaps = 8/217 (3%)

Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217
           ++ LRLVDG   C+GRVE+    EWG+VC++ W +E   V+C QLGC  A++A    + +
Sbjct: 48  DKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSS 107

Query: 218 PGRGPIHRDQVNCSGAEAYLWDC--PGLPGQHYCGHKEDAGAVCSE--HQSWRLTGGADR 273
            G G I  D V+C G E+ LWDC   G      C H++DAG  CS+  +   RLT G + 
Sbjct: 108 AGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNM 167

Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS--- 329
           C G++E+ F+G W TVCD  +    A V+C+ L CG+AV           SG +++    
Sbjct: 168 CSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLI 227

Query: 330 CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
           CNG E  L NC  +    + C  +  A V+CS    L
Sbjct: 228 CNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADL 264



 Score =  150 bits (380), Expect = 3e-36
 Identities = 118/408 (28%), Positives = 169/408 (41%), Gaps = 47/408 (11%)

Query: 45   VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
            +RL NG   C+G VE+  E SW   C   WD   A  VCR LGCG  EA +         
Sbjct: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCG--EAIN--------- 767

Query: 105  PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR----ARVTCAENRA 160
                A G+              + C+G E R+ +   H       R    A V C+E  +
Sbjct: 768  ----ATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS 823

Query: 161  LRLVDGGG--ACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
            LRL       ACAGR+E+  +G WG+V   +       VVCRQLGC    +  P      
Sbjct: 824  LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKA 883

Query: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPGQ-HYCGHKEDAGAVCSEHQSWRLTGGADRCEGQ 277
               P+  D V C      LW CP  P +       E+    C      RL  G   C G+
Sbjct: 884  MSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCD--NKIRLQEGPTSCSGR 941

Query: 278  VEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGE 333
            VE+   G W TVCD  W   +A+V+CQ LGCG A++  K       +G ++ +   C G 
Sbjct: 942  VEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGN 1001

Query: 334  ELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVTVKIEN 393
            E +L +C  R    + C     A V C+      ++S  + P    T             
Sbjct: 1002 ESSLWDCPARRWGHSECGHKEDAAVNCT------DISVQKTPQKATT------------G 1043

Query: 394  KESRELMLLIPSIVLGILLLGSLIFIAFILLRIKGKYALPVMVNHQHL 441
            + SR+   +   I LG++LL   + + F+  + + +  L V    ++L
Sbjct: 1044 RSSRQSSFIAVGI-LGVVLLAIFVALFFLTKKRRQRQRLAVSSRGENL 1090



 Score =  135 bits (339), Expect = 2e-31
 Identities = 99/313 (31%), Positives = 146/313 (46%), Gaps = 30/313 (9%)

Query: 41   ERLPVRLTNGSS--SCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98
            E + +RLT+ +S  +C+G +EV    +W     +         VCR LGC       ++ 
Sbjct: 820  EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADK---GKIN 876

Query: 99   PPTPELPPPPAAGNTSVAANATLAGAPALL--CSGAEWRLCEVVEHACRSDGRRARVTCA 156
            P + +     A        N      P  L  C  + W      E    S      +TC 
Sbjct: 877  PASLD----KAMSIPMWVDNVQCPKGPDTLWQCPSSPW------EKRLASPSEETWITC- 925

Query: 157  ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216
             +  +RL +G  +C+GRVE+   G WG+VCDD+WDL+DA VVC+QLGCG A++A     F
Sbjct: 926  -DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEF 984

Query: 217  TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWR-----LTGG 270
              G GPI  ++V C G E+ LWDCP    G   CGHKEDA   C++    +      TG 
Sbjct: 985  GQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGR 1044

Query: 271  ADRCEGQVEVHFRG-VWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYS 329
            + R    + V   G V   +  + ++ ++ +   Q L   +   R + L H +  R   S
Sbjct: 1045 SSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQRLAVSS---RGENLVHQIQYREMNS 1101

Query: 330  C-NGEELTLSNCS 341
            C N ++L L N S
Sbjct: 1102 CLNADDLDLMNSS 1114


>gi|44662834 CD163 antigen isoform a [Homo sapiens]
          Length = 1156

 Score =  201 bits (512), Expect = 1e-51
 Identities = 122/358 (34%), Positives = 174/358 (48%), Gaps = 24/358 (6%)

Query: 40  GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99
           G  L +RL  G S C+GTVEV ++      C   W  + A+ VCR LGCG A   S    
Sbjct: 368 GSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSY--- 424

Query: 100 PTPELPPPPAAGNTSVAANATLAGAPALL-CSGAEWR--LCEVVEHACRSDGRRARVTCA 156
              ++     A NT +  ++      +L  C   +W    C+  E A        ++TC+
Sbjct: 425 ---QVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEA--------KITCS 473

Query: 157 ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216
            +R  RLV G   C+GRVE+     WGS+CD  + LE A V+CR+L CG  V  L G HF
Sbjct: 474 AHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHF 533

Query: 217 TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGADRCE 275
             G G I  ++  C G E++L  CP  P  +  C H  D G VCS +   RL  G   CE
Sbjct: 534 GEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCE 593

Query: 276 GQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSG----RMYYSCN 331
           G+VE+   G W ++C+S W   +A VLCQ L CG A+  P G           R  + C 
Sbjct: 594 GRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCT 653

Query: 332 GEELTLSNCSWRFNNSNLCSQSLAARVLCSA--SRSLHNLSTPEVPASVQTVTIESSV 387
           G E  + +C      ++LC     A V+CS   S++L + ++  +  +  T+  ES+V
Sbjct: 654 GTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAV 711



 Score =  200 bits (509), Expect = 3e-51
 Identities = 114/308 (37%), Positives = 157/308 (50%), Gaps = 32/308 (10%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGA---EAASQLAPPT 101
           +RL NG + C G VE++   +W   C + WD   A  +C+ L CG A      ++     
Sbjct: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642

Query: 102 PEL---------------PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRS 146
            ++                 P  A   S+  +  +A   +++CSG + +       +   
Sbjct: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVA---SVICSGNQSQTLSSCNSSSLG 699

Query: 147 DGR-----RARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQ 201
             R      + V C E+  LRLV+GGG CAGRVE+   G WG++CDD+WDL DAHVVCRQ
Sbjct: 700 PTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQ 759

Query: 202 LGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260
           LGCG A+ A    HF  G GPI  D++ C+G E+ +W C     GQ  C HKEDAG +CS
Sbjct: 760 LGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819

Query: 261 EHQSWRLTGGADR--CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGL 318
           E  S RLT  A R  C G++EV + G W TV  S    +   V+C+ LGC    ++ K  
Sbjct: 820 EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGC---ADKGKIN 876

Query: 319 PHSLSGRM 326
           P SL   M
Sbjct: 877 PASLDKAM 884



 Score =  198 bits (503), Expect = 2e-50
 Identities = 119/340 (35%), Positives = 170/340 (50%), Gaps = 32/340 (9%)

Query: 40  GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99
           G  L +RLT G + CSG +E++ +  W   C   ++   A  +CR L CG A + S    
Sbjct: 154 GSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFS---- 209

Query: 100 PTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVV-----EHACRSDGRRARVT 154
                      G+++    +       L+C+G E  L         +H C      A V 
Sbjct: 210 -----------GSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNC-DHAEDAGVI 257

Query: 155 CAENR--ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212
           C++    +LRLVDG   C+GR+E+   GEWG++CDD WD  DA V C+QLGC  AV A+ 
Sbjct: 258 CSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317

Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQ--SWRLTG 269
            ++ + G G I  D V+C G E  +W C     G+HYC H EDAG  CS+      RL G
Sbjct: 318 RVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRG 377

Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY- 328
           G  RC G VEV  + +   VCD  W   EA V+C+ LGCG+A++    +   +     + 
Sbjct: 378 GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437

Query: 329 ---SCNGEELTLSNC-SWRFNNSNLCSQSLAARVLCSASR 364
              SCNG E +L +C +W++     C     A++ CSA R
Sbjct: 438 FLSSCNGNETSLWDCKNWQWGGLT-CDHYEEAKITCSAHR 476



 Score =  194 bits (493), Expect = 2e-49
 Identities = 119/343 (34%), Positives = 163/343 (47%), Gaps = 43/343 (12%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
           +RL +G + CSG VEV+++  W   C   W   A   +C  LGC             P  
Sbjct: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGC-------------PTA 97

Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG----------RRARVT 154
              P   N+S  A +       + C G E  L +     C+ DG          + A VT
Sbjct: 98  IKAPGWANSS--AGSGRIWMDHVSCRGNESALWD-----CKHDGWGKHSNCTHQQDAGVT 150

Query: 155 CAE--NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212
           C++  N  +RL  GG  C+GR+E+   G WG+VCDD ++++ A V+CRQL CG AV    
Sbjct: 151 CSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSG 210

Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSE--HQSWRLTG 269
             +F  G GPI  D + C+G E+ LW+C     G+H C H EDAG +CS+    S RL  
Sbjct: 211 SSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVD 270

Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTA------VERPKGLPHSLS 323
           G   C G++EV F+G W T+CD  W   +A V C+ LGC TA      V   KG  H   
Sbjct: 271 GVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWL 330

Query: 324 GRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
             +  SC G E  +  C       + C+ +  A V CS    L
Sbjct: 331 DSV--SCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDL 371



 Score =  171 bits (432), Expect = 3e-42
 Identities = 116/371 (31%), Positives = 157/371 (42%), Gaps = 69/371 (18%)

Query: 46  RLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELP 105
           RL  G   CSG VEV+   +W   C + +   AA  +CR L CG   +            
Sbjct: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSI----------- 527

Query: 106 PPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVV---EHACRSDGRRARVTCAENRA 160
                G            A    C G E  L  C V    E  C S  R   V C+    
Sbjct: 528 ----LGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTC-SHSRDVGVVCSRYTE 582

Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220
           +RLV+G   C GRVE+   G WGS+C+  WD+EDAHV+C+QL CG A+    G  F  G 
Sbjct: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642

Query: 221 GPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQS--------------- 264
           G I R   +C+G E ++ DCP    G   C  ++ A  +CS +QS               
Sbjct: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR 702

Query: 265 ----------------WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC 308
                            RL  G  RC G+VE++  G W T+CD  W  S+A V+C+ LGC
Sbjct: 703 PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762

Query: 309 GTAVERPKGLPHSLSGR-----MYYSCNGEELTL----------SNCSWRFNNSNLCSQS 353
           G A+    G  H   G          CNG+E  +           NC  + +   +CS+ 
Sbjct: 763 GEAI-NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEF 821

Query: 354 LAARVLCSASR 364
           ++ R+   ASR
Sbjct: 822 MSLRLTSEASR 832



 Score =  154 bits (390), Expect = 2e-37
 Identities = 83/217 (38%), Positives = 118/217 (54%), Gaps = 8/217 (3%)

Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217
           ++ LRLVDG   C+GRVE+    EWG+VC++ W +E   V+C QLGC  A++A    + +
Sbjct: 48  DKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSS 107

Query: 218 PGRGPIHRDQVNCSGAEAYLWDC--PGLPGQHYCGHKEDAGAVCSE--HQSWRLTGGADR 273
            G G I  D V+C G E+ LWDC   G      C H++DAG  CS+  +   RLT G + 
Sbjct: 108 AGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNM 167

Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS--- 329
           C G++E+ F+G W TVCD  +    A V+C+ L CG+AV           SG +++    
Sbjct: 168 CSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLI 227

Query: 330 CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
           CNG E  L NC  +    + C  +  A V+CS    L
Sbjct: 228 CNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADL 264



 Score =  150 bits (380), Expect = 3e-36
 Identities = 118/408 (28%), Positives = 169/408 (41%), Gaps = 47/408 (11%)

Query: 45   VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
            +RL NG   C+G VE+  E SW   C   WD   A  VCR LGCG  EA +         
Sbjct: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCG--EAIN--------- 767

Query: 105  PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR----ARVTCAENRA 160
                A G+              + C+G E R+ +   H       R    A V C+E  +
Sbjct: 768  ----ATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS 823

Query: 161  LRLVDGGG--ACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
            LRL       ACAGR+E+  +G WG+V   +       VVCRQLGC    +  P      
Sbjct: 824  LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKA 883

Query: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPGQ-HYCGHKEDAGAVCSEHQSWRLTGGADRCEGQ 277
               P+  D V C      LW CP  P +       E+    C      RL  G   C G+
Sbjct: 884  MSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCD--NKIRLQEGPTSCSGR 941

Query: 278  VEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGE 333
            VE+   G W TVCD  W   +A+V+CQ LGCG A++  K       +G ++ +   C G 
Sbjct: 942  VEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGN 1001

Query: 334  ELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVTVKIEN 393
            E +L +C  R    + C     A V C+      ++S  + P    T             
Sbjct: 1002 ESSLWDCPARRWGHSECGHKEDAAVNCT------DISVQKTPQKATT------------G 1043

Query: 394  KESRELMLLIPSIVLGILLLGSLIFIAFILLRIKGKYALPVMVNHQHL 441
            + SR+   +   I LG++LL   + + F+  + + +  L V    ++L
Sbjct: 1044 RSSRQSSFIAVGI-LGVVLLAIFVALFFLTKKRRQRQRLAVSSRGENL 1090



 Score =  135 bits (341), Expect = 9e-32
 Identities = 107/338 (31%), Positives = 157/338 (46%), Gaps = 34/338 (10%)

Query: 41   ERLPVRLTNGSS--SCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98
            E + +RLT+ +S  +C+G +EV    +W     +         VCR LGC       ++ 
Sbjct: 820  EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADK---GKIN 876

Query: 99   PPTPELPPPPAAGNTSVAANATLAGAPALL--CSGAEWRLCEVVEHACRSDGRRARVTCA 156
            P + +     A        N      P  L  C  + W      E    S      +TC 
Sbjct: 877  PASLD----KAMSIPMWVDNVQCPKGPDTLWQCPSSPW------EKRLASPSEETWITC- 925

Query: 157  ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216
             +  +RL +G  +C+GRVE+   G WG+VCDD+WDL+DA VVC+QLGCG A++A     F
Sbjct: 926  -DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEF 984

Query: 217  TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWR-----LTGG 270
              G GPI  ++V C G E+ LWDCP    G   CGHKEDA   C++    +      TG 
Sbjct: 985  GQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGR 1044

Query: 271  ADRCEGQVEVHFRG-VWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYS 329
            + R    + V   G V   +  + ++ ++ +   Q L   +   R + L H +  R   S
Sbjct: 1045 SSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQRLAVSS---RGENLVHQIQYREMNS 1101

Query: 330  C-NGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
            C N ++L L N S    NS+  S   +A  L S S+ L
Sbjct: 1102 CLNADDLDLMNSS---ENSHE-SADFSAAELISVSKFL 1135


>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
            sapiens]
          Length = 1453

 Score =  199 bits (506), Expect = 7e-51
 Identities = 111/288 (38%), Positives = 153/288 (53%), Gaps = 23/288 (7%)

Query: 45   VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAAS---QLAPPT 101
            VRL NG S C G VE+ +   W   C   WD   A  +CR L CG A + +    +   +
Sbjct: 900  VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERS 959

Query: 102  PELPPPP--AAGNTSVAANA--TLAGAP--------ALLCSGAEWR-----LCEVVEHAC 144
              +        GN S+  N   T+ GAP        +++C+G+  +     L  V +   
Sbjct: 960  VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYL 1019

Query: 145  RSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGC 204
             +    + + C E++ LRLVDG   CAGRVE+   G WG++CDD WDL DAHVVC++LGC
Sbjct: 1020 SAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGC 1079

Query: 205  GWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQ 263
            G A  A    HF  G GPI  D +NC+G E++LW CP    GQH C HKEDAG +CSE  
Sbjct: 1080 GVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFT 1139

Query: 264  SWRLTG--GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309
            + RL      + C G++EV + G W +V       + A ++C+ LGCG
Sbjct: 1140 ALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCG 1187



 Score =  197 bits (502), Expect = 2e-50
 Identities = 123/343 (35%), Positives = 172/343 (50%), Gaps = 32/343 (9%)

Query: 34  SELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEA 93
           S +   G  L +RL +GS++CSG VEVR+   W   C   W +  A  VC+ LGC  +  
Sbjct: 358 SVICSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVF 417

Query: 94  ASQLAPPTPE-----LPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG 148
            S+ A P+ E     +      GN S   + T  G     C               RSD 
Sbjct: 418 GSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFR-------------RSD- 463

Query: 149 RRARVTCAENRAL--RLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206
             A V C++   L  RLV     C GR+E+   GEWG+VC D W   +A VVC+QLGCG 
Sbjct: 464 --AGVICSDKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGK 521

Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSW 265
            +      +F    GPI  D V+C G E+ +WDC     G+H C H+ED    CS   +W
Sbjct: 522 PMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATW 581

Query: 266 --RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLS 323
             RL GG++RC G++EV+F+G W TVCD  W    A V+C  L C +++    GL ++ +
Sbjct: 582 GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSI-IGMGLGNAST 640

Query: 324 --GRMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
             G+++    SC+G+E  L +C      +N CS S    V+CS
Sbjct: 641 GYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683



 Score =  184 bits (468), Expect = 2e-46
 Identities = 121/342 (35%), Positives = 155/342 (45%), Gaps = 32/342 (9%)

Query: 40  GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99
           G  L +RL NG   CSGTVEV+ +  W   C   W++ A+  VC+ LGC  + A  +   
Sbjct: 43  GTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQ 102

Query: 100 PTPE-----LPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVT 154
                    L      GN S              C   EW       H C   G    V 
Sbjct: 103 AVTRHGKIWLDDVSCYGNESALWE----------CQHREWG-----SHNCYH-GEDVGVN 146

Query: 155 C--AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212
           C    N  LRLVDG  +C+GRVE+     WG++CDD W+L  A VVCRQLGC  +  +  
Sbjct: 147 CYGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSG 206

Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVC--SEHQSWRLTG 269
            ++      PI  D + C G E  LW+C     G H C H ED    C  S     RL G
Sbjct: 207 VVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVG 266

Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMY-- 327
           G +RC G+VE+  +G W TVC  +W  + A V+C+ LGCGTA+    GLPH  SG     
Sbjct: 267 GTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHF-AGLPHLQSGSDVVW 325

Query: 328 ---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
               SC+G E  L +C      +  C       V+CS    L
Sbjct: 326 LDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADL 367



 Score =  181 bits (460), Expect = 1e-45
 Identities = 120/368 (32%), Positives = 173/368 (47%), Gaps = 31/368 (8%)

Query: 43   LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102
            + +RL  GSS C+G VEV ++ +    C   W    AE VCR L CG A   S+      
Sbjct: 688  MELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSR------ 741

Query: 103  ELPPPPAAGNTS--VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRA 160
                P     T   + +N+   G  A L     W   E  + AC  +   A + C+ +R 
Sbjct: 742  ---EPHFTERTLHILMSNSGCTGGEASLWDCIRW---EWKQTACHLN-MEASLICSAHRQ 794

Query: 161  LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220
             RLV     C+GRVE+     W SVCD  + L  A+V+CR+L CG A+    G HF  G 
Sbjct: 795  PRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGN 854

Query: 221  GPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVE 279
            G    ++  C G+E +L  CP +   +  C H  + G VCS +   RL  G  +C+GQVE
Sbjct: 855  GLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVE 914

Query: 280  VHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKG-LPHSLSGRMY---YSCNGEEL 335
            ++  G W ++CD+ W P +A+VLC+ L CGTA+    G      S R++   + C G E 
Sbjct: 915  INVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNES 974

Query: 336  TLSNCSWRFNNSNLCSQSLAARVLCSASRS------LHNLSTPEVPASVQTVTIESSVTV 389
             L NC      +  C       V+C+ S +      L N+S P + A       E S  +
Sbjct: 975  LLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSA-----VPEGSALI 1029

Query: 390  KIENKESR 397
             +E+K  R
Sbjct: 1030 CLEDKRLR 1037



 Score =  173 bits (439), Expect = 4e-43
 Identities = 111/338 (32%), Positives = 154/338 (45%), Gaps = 30/338 (8%)

Query: 43  LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102
           L +RL +G++SCSG VEV+ +  W   C   W+   A  VCR LGC  +  +S +     
Sbjct: 153 LGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPA 212

Query: 103 ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVE-----HACRSDGRRARVTCAE 157
            L P                    +LC G E  L          H C S      +TC +
Sbjct: 213 VLRP---------------IWLDDILCQGNELALWNCRHRGWGNHDC-SHNEDVTLTCYD 256

Query: 158 NR--ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH 215
           +    LRLV G   C GRVE+   G WG+VC   W+   A VVC+QLGCG A+      H
Sbjct: 257 SSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPH 316

Query: 216 FTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHY-CGHKEDAGAVCSE--HQSWRLTGGAD 272
              G   +  D V+CSG E++LWDC      ++ C H+ D   +CS+      RL  G++
Sbjct: 317 LQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLELRLADGSN 376

Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY---- 328
            C G+VEV     W T+CD  W   +A V+C+ LGC  +V   +    S   R  +    
Sbjct: 377 NCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSI 436

Query: 329 SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
           SC G E  L +C++       C +   A V+CS    L
Sbjct: 437 SCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADL 474



 Score =  152 bits (384), Expect = 1e-36
 Identities = 112/368 (30%), Positives = 153/368 (41%), Gaps = 55/368 (14%)

Query: 46   RLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELP 105
            RL      CSG VEV+   +W   C + +   AA  +CR L CG A + S          
Sbjct: 796  RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLS---------- 845

Query: 106  PPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVVEHACRS--DGRRARVTCAENRAL 161
                 G+     N  L  A    C G+E  L  C +V+H   +    R   V C+    +
Sbjct: 846  ----VGDHFGKGNG-LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDV 900

Query: 162  RLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRG 221
            RLV+G   C G+VE+   G WGS+CD  WD EDA V+CRQL CG A+    G +      
Sbjct: 901  RLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSV 960

Query: 222  PIHRDQVNCSGAEAYLWDCP-GLPGQHYCGH----------------------------- 251
             +   + +C G E+ L +C   + G   C H                             
Sbjct: 961  RVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLS 1020

Query: 252  --KEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309
               E +  +C E +  RL  G  RC G+VE++  G W T+CD  W  S+A V+CQ LGCG
Sbjct: 1021 AVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG 1080

Query: 310  TAVERPKGLPHSL-SGRMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRS 365
             A            SG ++    +C G E  L  C  R    + C     A V+CS   +
Sbjct: 1081 VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTA 1140

Query: 366  LHNLSTPE 373
            L   S  E
Sbjct: 1141 LRLYSETE 1148



 Score =  152 bits (383), Expect = 1e-36
 Identities = 108/333 (32%), Positives = 143/333 (42%), Gaps = 36/333 (10%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
           +RL  GS+ CSG +EV  +  W   C   W+S+AA  VC  L C  +     L       
Sbjct: 583 LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGL------- 635

Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG---------RRARVTC 155
                 GN S           +  C G E  L      +CR+ G             V C
Sbjct: 636 ------GNASTGYGKIWLDDVS--CDGDESDLW-----SCRNSGWGNNDCSHSEDVGVIC 682

Query: 156 --AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPG 213
             A +  LRLV G   CAG+VE+   G  G +C + W +  A VVCRQL CG A++    
Sbjct: 683 SDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSRE 742

Query: 214 LHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGAD 272
            HFT     I      C+G EA LWDC      Q  C    +A  +CS H+  RL G   
Sbjct: 743 PHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLVGADM 802

Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPK----GLPHSLSGRMYY 328
            C G+VEV     W +VCDS++    A VLC+ L CG A+        G  + L+    +
Sbjct: 803 PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKF 862

Query: 329 SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
            C G E  L+ C    +  + C  S    V+CS
Sbjct: 863 QCEGSETHLALCPIVQHPEDTCIHSREVGVVCS 895



 Score =  145 bits (366), Expect = 1e-34
 Identities = 124/410 (30%), Positives = 178/410 (43%), Gaps = 66/410 (16%)

Query: 45   VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
            +RL +G S C+G VE+  +  W   C   WD   A  VC+ LGCG               
Sbjct: 1036 LRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG--------------- 1080

Query: 105  PPPPAAGNTSVAANATLAGAPALL----CSGAEWRLCEVV-----EHACRSDGRRARVTC 155
                 A N +V+A+      P  L    C+G E  L +       +H CR     A V C
Sbjct: 1081 ----VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHK-EDAGVIC 1135

Query: 156  AENRALRLVDGGG--ACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW-AVQALP 212
            +E  ALRL       +CAGR+E+  +G WGSV         A +VCRQLGCG   V +L 
Sbjct: 1136 SEFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLA 1195

Query: 213  GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSEHQSWRLTGGAD 272
             L  T G G +  D + C      +W C   P +       +   +  E +  R+ GG  
Sbjct: 1196 PLSKT-GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRI-RVRGGDT 1253

Query: 273  RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS-- 329
             C G+VE+   G W TVCD  W  +EA+V+CQ LGCG+A+   +       +G ++    
Sbjct: 1254 ECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDM 1313

Query: 330  -CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVT 388
             C G E  L +C  +    + C     A V CS                          +
Sbjct: 1314 RCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQ------------------------S 1349

Query: 389  VKIENKESRELMLLIPSIVLGILLLGSLIFIAFIL-LRIKGKYALPVMVN 437
            +K  N  S  L L++ SI  G+LLL  ++FI F+   R++ +  LP+ V+
Sbjct: 1350 LKSLNASSGHLALILSSI-FGLLLL--VLFILFLTWCRVQKQKHLPLRVS 1396


>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 343

 Score =  192 bits (487), Expect = 1e-48
 Identities = 106/244 (43%), Positives = 130/244 (53%), Gaps = 30/244 (12%)

Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
           ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G
Sbjct: 17  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 76

Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS--------EHQSW----- 265
            GPI  D V CSG E+YLW CP      H CGH EDAG +CS          +SW     
Sbjct: 77  SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFL 136

Query: 266 ------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVE 313
                       RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A  
Sbjct: 137 CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 196

Query: 314 RPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNL 369
            P        SG +      C+G E  L +C      S+ C     A V+CS S ++   
Sbjct: 197 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGSWAVAGP 256

Query: 370 STPE 373
             P+
Sbjct: 257 RRPQ 260



 Score =  173 bits (439), Expect = 4e-43
 Identities = 104/252 (41%), Positives = 123/252 (48%), Gaps = 37/252 (14%)

Query: 43  LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102
           L +RL NG   C G VEV    SW   C   WD+  A  VCR LGCG A     LAP   
Sbjct: 16  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA----MLAPGNA 71

Query: 103 E---------LPPPPAAGNTS----------VAANATLAGAPALLCSGAEWRLCEVVEHA 143
                     L     +GN S          ++ N   +    ++CSG   R        
Sbjct: 72  RFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRT------P 125

Query: 144 CRSDGRRARVTCA-----ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVV 198
            R     +R  C+      + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VV
Sbjct: 126 IRPRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 185

Query: 199 CRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGA 257
           CRQLGCGWA  A     F  G GPI  D V CSG E+YLW CP      H CGH EDAG 
Sbjct: 186 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGV 245

Query: 258 VCSEHQSWRLTG 269
           +CS   SW + G
Sbjct: 246 ICS--GSWAVAG 255



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 26/56 (46%), Positives = 29/56 (51%)

Query: 39  PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94
           P   L +RL NG   C G VEV    SW   C   WD+  A  VCR LGCG A +A
Sbjct: 142 PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 197


>gi|5174411 CD5 molecule-like [Homo sapiens]
          Length = 347

 Score =  191 bits (485), Expect = 2e-48
 Identities = 123/341 (36%), Positives = 155/341 (45%), Gaps = 42/341 (12%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
           VRL  G   C G VEV  +  W   C   WD +    +CR LGCG A        P+  L
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGT-----PSGIL 78

Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVVEHACRSDGRRARVTCAENRA-- 160
             PPA     V   +       + C+G E  L  CE  E    S    A  +C    +  
Sbjct: 79  YEPPAEKEQKVLIQS-------VSCTGTEDTLAQCEQEEVYDCSHDEDAGASCENPESSF 131

Query: 161 ------LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGL 214
                 +RL DG G C GRVE+    +W +VC   W L  A VVCRQLGCG AV      
Sbjct: 132 SPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRC 191

Query: 215 H-FTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGAD 272
           +    GR PI   Q++CSG EA L DCP  P G++ C H ED    C +    RL GG +
Sbjct: 192 NKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDN 251

Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYS--- 329
            C G++EV  +GVW +VCD  W   E +V+C+ LGCG      K L  S   R  Y    
Sbjct: 252 LCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCG------KSLSPSFRDRKCYGPGV 305

Query: 330 ---------CNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
                    C+GEE +L  C  RF   + C+      V+CS
Sbjct: 306 GRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  137 bits (344), Expect = 4e-32
 Identities = 84/224 (37%), Positives = 110/224 (49%), Gaps = 23/224 (10%)

Query: 156 AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH 215
           A    +RLV G   C GRVE+ + G+WG+VCDD WD++D  V+CR+LGCG A     G+ 
Sbjct: 19  ASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGIL 78

Query: 216 FTPGRGPIHRDQ------VNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSEHQS----- 264
           + P   P  ++Q      V+C+G E  L  C      + C H EDAGA C   +S     
Sbjct: 79  YEP---PAEKEQKVLIQSVSCTGTEDTLAQCE-QEEVYDCSHDEDAGASCENPESSFSPV 134

Query: 265 ---WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHS 321
               RL  G   C+G+VEV  +  W TVC + W    AKV+C+ LGCG AV   K     
Sbjct: 135 PEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKH 194

Query: 322 LSGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360
             GR        SC+G E TL +C       N C+      V C
Sbjct: 195 AYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC 238


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score =  179 bits (455), Expect = 6e-45
 Identities = 143/419 (34%), Positives = 173/419 (41%), Gaps = 79/419 (18%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA------SQLA 98
           +RL +G   C+G +EV     W   C   WD R A   CR LGCGGA AA       + A
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 99  PPTPELPPPPAAGNTSVAANATLAGAPALLCS--------------------------GA 132
            P   L      GN          G  A +CS                          GA
Sbjct: 80  GPV-WLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGA 138

Query: 133 EWR--LCEV--------VEHACRSDG-------------RRARVTCA--------ENRAL 161
            W   L E+        V HA R  G             ++A+ T A            L
Sbjct: 139 PWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERL 198

Query: 162 RLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRG 221
           RLV G   CAGR+E+   G WG+VCDD WDL DA V CR+LGCG A+ A  G  F PG G
Sbjct: 199 RLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAG 258

Query: 222 PIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS-EHQSWRLTGGADRCEGQVE 279
           P+  D V C G E  L DCP  P G+  C H EDAG VC+      RL  G   C G++E
Sbjct: 259 PVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLE 318

Query: 280 VHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEEL 335
           V   G W +VCD  W   +A V C+ LGCG A+  P G      SG +      C G E 
Sbjct: 319 VWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNET 378

Query: 336 TLSNCSWRFNNSNLCSQSLAARVLCS---------ASRSLHNLSTPEVPASVQTVTIES 385
            L  C  R    + C     A  +C           + +  N STP   AS    T+ S
Sbjct: 379 ALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTS 437



 Score =  149 bits (376), Expect = 8e-36
 Identities = 97/242 (40%), Positives = 112/242 (46%), Gaps = 14/242 (5%)

Query: 20  SPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAA 79
           SP P    +T +       P +   +RL +G   C+G +EV     W   C   WD R A
Sbjct: 174 SPRPKQAKSTRAPLLTTGAPRQER-LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDA 232

Query: 80  EAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL-CSGAEWRLCE 138
              CR LGCGGA AA   A         P AG   +       G  AL  C  + W    
Sbjct: 233 AVACRELGCGGALAAPGGA------RFGPGAGPVWMDDVGCGGGEQALRDCPRSPWG--- 283

Query: 139 VVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVV 198
                C        V       LRL DG   CAGR+E+   G WGSVCDD WDL DA V 
Sbjct: 284 --RSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVA 341

Query: 199 CRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGA 257
           CR+LGCG A+ A  G  F  G GPI  D + C G E  L  CP  P GQH C H+EDAGA
Sbjct: 342 CRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGA 401

Query: 258 VC 259
           VC
Sbjct: 402 VC 403



 Score =  119 bits (297), Expect = 1e-26
 Identities = 86/271 (31%), Positives = 107/271 (39%), Gaps = 51/271 (18%)

Query: 39  PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALG----------- 87
           P  RL  RL +G   C+G +EV     W   C   WD R A   CR LG           
Sbjct: 300 PAPRL--RLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGA 357

Query: 88  ---------------CGGAEAASQLAPPTP-----------------ELP----PPPAAG 111
                          C G E A +  P  P                  +P    PP A  
Sbjct: 358 FFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPT 417

Query: 112 NTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACA 171
           +++ +     A  P    +        V                A +  LRLV G   C+
Sbjct: 418 DSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCS 477

Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGL-HFTPGRGPIHRDQVNC 230
           GR+E+     WG+VCDD+WD+ D+ VVCR+LGCG   Q  P    F  G GPI  D V C
Sbjct: 478 GRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGC 537

Query: 231 SGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260
            G EA L DCP  P G+H C H ED G  C+
Sbjct: 538 VGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  113 bits (282), Expect = 6e-25
 Identities = 51/106 (48%), Positives = 65/106 (61%), Gaps = 1/106 (0%)

Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220
           +RL DG   CAGR+E+   G WG+VCDD WDL DA V C +LGCG     +   H+ PG 
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 221 GPIHRDQVNCSGAEAYLWDCP-GLPGQHYCGHKEDAGAVCSEHQSW 265
           GPI  D + C G+EA L DCP G  G+H C H+ED G  C+ +  +
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDY 877



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 36/104 (34%), Positives = 47/104 (45%), Gaps = 20/104 (19%)

Query: 11  LTAALSGHPSPAPPDQLNTSSAESELWEPGERL---PVRLTNGSSSCSGTVEVRLEASWE 67
           +T+   G    +PP      ++ + LWEPG       +RL  G S CSG +EV  +  W 
Sbjct: 435 MTSQAPGTAGVSPPP-----ASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWG 489

Query: 68  PACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAG 111
             C   WD R +  VCR LGCGG +             P PAAG
Sbjct: 490 TVCDDSWDMRDSAVVCRELGCGGPQ------------QPDPAAG 521



 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 8/81 (9%)

Query: 266 RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPK-GLPHSLSG 324
           RL  G +RC G++EV   G W TVCD  W   +A V C  LGCG    RP+ G  H   G
Sbjct: 773 RLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKV--RPRVGKTHYGPG 830

Query: 325 R-----MYYSCNGEELTLSNC 340
                     C G E +LS+C
Sbjct: 831 TGPIWLDDMGCKGSEASLSDC 851



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 52/200 (26%), Positives = 68/200 (34%), Gaps = 44/200 (22%)

Query: 21  PAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAE 80
           PAP   ++T+  ES L+       VRL +G + C+G +EV     W   C   WD R A 
Sbjct: 755 PAPSPSVSTTG-ESGLFR------VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDAT 807

Query: 81  AVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVV 140
             C  LGCG                  P  G T             + C G+E  L +  
Sbjct: 808 VACWELGCGKVR---------------PRVGKTHYGPGTGPIWLDDMGCKGSEASLSD-- 850

Query: 141 EHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCR 200
              C S G   +  C         D G  C G  +  ++  W      TWD         
Sbjct: 851 ---CPS-GAWGKHNCDHEE-----DVGLTCTGYTDYDDYPPW------TWDPTSR----E 891

Query: 201 QLGCGWAVQALPGLHFTPGR 220
            L  G     +PG H  P R
Sbjct: 892 DLAKGTTTAGVPG-HTLPWR 910


>gi|18152779 scavenger receptor cysteine rich domain containing,
           group B (4 domains) [Homo sapiens]
          Length = 575

 Score =  174 bits (442), Expect = 2e-43
 Identities = 144/431 (33%), Positives = 170/431 (39%), Gaps = 115/431 (26%)

Query: 20  SPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAA 79
           S APP  L    +E           VRL  G++ C G VE+     W   C   W    A
Sbjct: 173 SRAPPTTLPNGKSEGS---------VRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDA 223

Query: 80  EAV-----------------------------------------CRALG-----CGGAEA 93
             V                                         C++LG     CG  E 
Sbjct: 224 AVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHED 283

Query: 94  ASQLA----PPTPELPPPPA-----AGNTSVAANAT--LAGAPALLCSGAEWRLCEVVEH 142
           A  L     PPT    P  A     A  T  +A            L + A W        
Sbjct: 284 AGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWA------- 336

Query: 143 ACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202
           A +  GR           LRLV G G C GRVE+L  G WG+VCDD WD  DA V CR+ 
Sbjct: 337 AGKKSGR-----------LRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREA 385

Query: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSE 261
           GCG A+ A    HF  GRGP+  D V C+G EA L DC  L  GQH CGH EDAGA+C+ 
Sbjct: 386 GCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445

Query: 262 HQS------------------------WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPS 297
            +                          RL  GA RCEG+VE++    W TVCD  W   
Sbjct: 446 PEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLR 505

Query: 298 EAKVLCQSLGCGTAVERPKGLPHSLSGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQ 352
            A VLC+ LGCG A+  P G  H   GR         C GEE  L  CS    +++ C  
Sbjct: 506 AAGVLCRQLGCGQALAAP-GEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDH 564

Query: 353 SLAARVLCSAS 363
           S  A VLC  S
Sbjct: 565 SEDASVLCQPS 575



 Score =  169 bits (428), Expect = 8e-42
 Identities = 134/400 (33%), Positives = 158/400 (39%), Gaps = 86/400 (21%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
           +RL  G S C G +EV    SW   C   WD   A  VCR LGCG       LA P P  
Sbjct: 58  LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG-------LALPVPRP 110

Query: 105 PPPPAAGNTSVAANATLAGAPALL--CSGAEWRL-----CEVVEHAC-----------RS 146
                     +  N    G  A L  C    W +      E V   C           + 
Sbjct: 111 LAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM 170

Query: 147 DGRRARVTCAEN----RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202
              RA  T   N     ++RLV G   C GRVE+L  G WG+VCDD W L DA VVCRQL
Sbjct: 171 LTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQL 230

Query: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS- 260
           GCG A+ A     F  G G I  D V+C G E  L  C  L  G H CGH EDAGA+C+ 
Sbjct: 231 GCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290

Query: 261 ---------------EHQSW----------------------------------RLTGGA 271
                          E  +W                                  RL GG 
Sbjct: 291 LGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGP 350

Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGR-----M 326
             C G+VEV   G W TVCD +W  ++A+V C+  GCG A+    GL H   GR      
Sbjct: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPAL-GATGLGHFGYGRGPVLLD 409

Query: 327 YYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
              C G E  LS+C       + C     A  LC+    L
Sbjct: 410 NVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEEL 449



 Score =  130 bits (328), Expect = 3e-30
 Identities = 93/261 (35%), Positives = 114/261 (43%), Gaps = 29/261 (11%)

Query: 19  PSPAPPDQLNTSSAESELWEPGERLP-VRLTNGSSSCSGTVEVRLEASWEPACGALWDSR 77
           P P+    L T++A    W  G++   +RL  G   C G VEV     W   C   WD  
Sbjct: 321 PQPSRETALLTTAA----WAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFA 376

Query: 78  AAEAVCRALGCGGAEAASQLA----PPTPELPPPPAAGNTSVAANATL------------ 121
            A   CR  GCG A  A+ L        P L        T    +               
Sbjct: 377 DARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHH 436

Query: 122 --AGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEH 179
             AGA   LC+G E    +V +    S+  R       +  LRLV+G   C GRVE+   
Sbjct: 437 EDAGA---LCAGPEELGLQVQQDG--SETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLG 491

Query: 180 GEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWD 239
             WG+VCDD WDL  A V+CRQLGCG A+ A    HF PGRGPI  D V C G E+ L  
Sbjct: 492 QRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLL 551

Query: 240 CPGLP-GQHYCGHKEDAGAVC 259
           C  +    H C H EDA  +C
Sbjct: 552 CSHIRWDAHNCDHSEDASVLC 572



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 39/103 (37%), Positives = 50/103 (48%), Gaps = 6/103 (5%)

Query: 263 QSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL 322
           Q  RL GG  RC G++EV   G W +VCD +W   +A V+C+ LGCG A+  P+ L    
Sbjct: 56  QELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG- 114

Query: 323 SGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360
            GR         C G+E  LS C  R    + C       VLC
Sbjct: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score =  170 bits (431), Expect = 3e-42
 Identities = 114/344 (33%), Positives = 151/344 (43%), Gaps = 36/344 (10%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
           VRL  G +   GTVEV     W   C + WD   A  +C  L  GG   A Q        
Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQT------- 222

Query: 105 PPPPAAGNTSVA---ANATLAGAPA--LLCSGAEWR--LCEVVEHACRSDGRRARVTCAE 157
              P +G   +    +N    G     LLC    W+  +C             A VTC+ 
Sbjct: 223 ---PFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCP--------QKMAAAVTCSF 271

Query: 158 NRA-----LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212
           +       +RL  G     GRVE+   G+WG+VCDD WD  DA V+CRQLG     +A  
Sbjct: 272 SHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWH 331

Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSW--RLTG 269
             +F  G GP+  D+V C+G E  +  CP    G+H CGHKEDAG  C+       RL G
Sbjct: 332 QAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAG 391

Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMY-- 327
           G    EG++EV++RG W TVCD  W      V+C+ LG     +         +G ++  
Sbjct: 392 GKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLD 451

Query: 328 -YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370
             SC+G+E     CS R    + CS      + C      H LS
Sbjct: 452 DVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLS 495



 Score =  149 bits (375), Expect = 1e-35
 Identities = 109/332 (32%), Positives = 142/332 (42%), Gaps = 28/332 (8%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
           +RL  GSS   G VE+     W   C   WD   AE +CR LG  G   A   A    E 
Sbjct: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAY-FGEG 338

Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAE--NRALR 162
             P          N          C  + W      EH C      A V+C    +  +R
Sbjct: 339 SGPVMLDEVRCTGNELSIEQ----CPKSSWG-----EHNC-GHKEDAGVSCTPLTDGVIR 388

Query: 163 LVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGP 222
           L  G G+  GR+E+   G+WG+VCDD W   + +VVCRQLG  +  QA    HF    GP
Sbjct: 389 LAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGP 447

Query: 223 IHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVC---------SEHQSWRLTGGAD 272
           I  D V+CSG E     C     G+H C H+ED    C         S     RL  G +
Sbjct: 448 IWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGEN 507

Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC-GTAVERPKGLPHSLSGRMY---Y 328
           + EG+VEV   G W T+CD  W   +A V+C+ LG  G A  R         G ++    
Sbjct: 508 KKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNV 567

Query: 329 SCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360
            C G E +L++C  +    + C  S  A V+C
Sbjct: 568 KCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599



 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 71/215 (33%), Positives = 94/215 (43%), Gaps = 16/215 (7%)

Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219
           ++RL  G     G VE+   G WG+VC   WD  DA V+C QL  G    A        G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPGQ-HYCGHKEDAGAVCSEHQS-----WRLTGGADR 273
             PI+   V C G E  +  C     Q   C  K  A   CS          RL GG+  
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSV 288

Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLG-CGTAVERPKGLPHSLSGRMYYS--- 329
            EG+VE++  G W TVCD +W  ++A+V+C+ LG  G A    +      SG +      
Sbjct: 289 HEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVR 348

Query: 330 CNGEELTLSNC---SWRFNNSNLCSQSLAARVLCS 361
           C G EL++  C   SW  +N   C     A V C+
Sbjct: 349 CTGNELSIEQCPKSSWGEHN---CGHKEDAGVSCT 380



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 47/122 (38%), Positives = 58/122 (47%), Gaps = 16/122 (13%)

Query: 252 KEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSL---GC 308
           K D G     H S RL GG +  EG VEV+  GVW TVC S W  S+A V+C  L   G 
Sbjct: 157 KVDWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGK 216

Query: 309 GTAVERPKGLPHSLSG----RMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
           G A + P       SG     +Y+S   C G+E  +  C        +C Q +AA V CS
Sbjct: 217 GIAKQTP------FSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCS 270

Query: 362 AS 363
            S
Sbjct: 271 FS 272



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 20/55 (36%), Positives = 26/55 (47%)

Query: 44  PVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98
           PVRL +G +   G VEV +   W   C   W  + A  +CR LG  G   A  +A
Sbjct: 499 PVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMA 553


>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
          Length = 753

 Score =  135 bits (340), Expect = 1e-31
 Identities = 109/360 (30%), Positives = 147/360 (40%), Gaps = 63/360 (17%)

Query: 56  GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSV 115
           G VEVRL   W   C   W +  +  VC  LG    +  +             + G   V
Sbjct: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246

Query: 116 AANATLAGAPALLCSGAEWRLCEVVE----------------HACRSDGRRARVTCAENR 159
           A   T A     LCS   +R  +                   +A  S  ++ + +  +  
Sbjct: 247 ACVGTEAHLS--LCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGE 304

Query: 160 A-LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
           A +RL  G     GRVE+L+   WG+VCD  WDL  A VVCR+LG G A +AL G     
Sbjct: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364

Query: 219 GRGPIHRDQVNCSGAEAYLWDCP--GLPGQHYCGHKEDAGAVCS-----EHQSWRLTGGA 271
           G G IH  +V CSG E  LW CP   +  +  C H +DAG  C+          RL+GG 
Sbjct: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAED-CSHSQDAGVRCNLPYTGAETRIRLSGGR 423

Query: 272 DRCEGQVEVHFRGV----WNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMY 327
            + EG+VEV   G     W  +C  +W   EA V C+ LG G A        H L    Y
Sbjct: 424 SQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYA-------NHGLQETWY 476

Query: 328 YS-------------CNGEELTLSNCS------------WRFNNSNLCSQSLAARVLCSA 362
           +              C G EL+L  C+             RF    +CS++ +  +L SA
Sbjct: 477 WDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSA 536



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 67/214 (31%), Positives = 90/214 (42%), Gaps = 40/214 (18%)

Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231
           GRVE+   GEWG++CDD + L+ AH++CR+LG   A        + PG G I  D ++CS
Sbjct: 56  GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGADR----------------- 273
           G E  + +C     G   C H EDAG +C +    RL G +D                  
Sbjct: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQ---RLPGFSDSNVIEVEHHLQVEEVRIR 172

Query: 274 ------------CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHS 321
                        EG VEV     W+ VCD  W    + V+C  LG  +           
Sbjct: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRL 232

Query: 322 LSGRMYYS-------CNGEELTLSNCSWRFNNSN 348
           L+ R  +S       C G E  LS CS  F  +N
Sbjct: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRAN 266



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 75/264 (28%), Positives = 98/264 (37%), Gaps = 37/264 (14%)

Query: 21  PAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAE 80
           P P    ++   + +  +P     VRL  G+    G VEV   ++W   C   WD  AA 
Sbjct: 283 PGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAAS 342

Query: 81  AVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCE-- 138
            VCR LG G A                 A     +           + CSG E  L +  
Sbjct: 343 VVCRELGFGSAR---------------EALSGARMGQGMGAIHLSEVRCSGQELSLWKCP 387

Query: 139 ---VVEHACRSDGRRARVTC------AENRALRLVDGGGACAGRVEMLEHG----EWGSV 185
              +    C S  + A V C      AE R +RL  G     GRVE+   G     WG +
Sbjct: 388 HKNITAEDC-SHSQDAGVRCNLPYTGAETR-IRLSGGRSQHEGRVEVQIGGPGPLRWGLI 445

Query: 186 CDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRG--PIHRDQVNCSGAEAYLWDCPGL 243
           C D W   +A V CRQLG G+A   L    +        +    V C+G E  L  C   
Sbjct: 446 CGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH 505

Query: 244 PGQHYC---GHKEDAGAVCSEHQS 264
                C   G +  AG +CSE  S
Sbjct: 506 GTHITCKRTGTRFTAGVICSETAS 529



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 21/161 (13%)

Query: 240 CPGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADR-CEGQVEVHFRGVWNTVCDSEWYPSE 298
           C G P     G ++ AG   S+   +RL G   +  EG+VE+   G W T+CD ++    
Sbjct: 23  CLGSPSPS-TGPEKKAG---SQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQA 78

Query: 299 AKVLCQSLGCGTAVERPKGLPHSL-----SGRMY---YSCNGEELTLSNCSWRFNNSNLC 350
           A +LC+ LG   A     G  HS      +GR++    SC+G E +++ C+ R   ++ C
Sbjct: 79  AHILCRELGFTEAT----GWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDC 134

Query: 351 SQSLAARVLCSASR----SLHNLSTPEVPASVQTVTIESSV 387
           +    A V+C   R    S  N+   E    V+ V I  +V
Sbjct: 135 THDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175


>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
          Length = 756

 Score =  134 bits (337), Expect = 3e-31
 Identities = 109/334 (32%), Positives = 136/334 (40%), Gaps = 52/334 (15%)

Query: 56  GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGG-AEAASQLAPPTPELPPPPAAGNTS 114
           G VEV+ E  W   C   W    +  VC  LG        S       +L          
Sbjct: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236

Query: 115 VAANATLAGAPALLCSGAEWRL--CEVVEHACRSD-------GRRARVTC---------- 155
              N        + C G E  +  C+V     R         G  A V+C          
Sbjct: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK 296

Query: 156 ---------AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206
                    AE   +RL  G     GRVE+L + +WG+VCD  W+L  A VVCRQLG G 
Sbjct: 297 TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGS 356

Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSE---- 261
           A +AL G     G GPIH  +V C G E  L DCP L G Q+ C H+ DA   C+     
Sbjct: 357 AREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMG 416

Query: 262 -HQSWRLTGGADRCEG--QVEVHFRGV--WNTVCDSEWYPSEAKVLCQSLGCGTAVERPK 316
                RL GG    EG  +V+V   GV  W +VC   W  +EA V C+ LG G A+   K
Sbjct: 417 FQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYK 476

Query: 317 ------GLPHS----LSGRMYYSCNGEELTLSNC 340
                 G P +    +SG     C+G EL L  C
Sbjct: 477 ETWFWSGTPRAQEVVMSG---VRCSGTELALQQC 507



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 67/218 (30%), Positives = 91/218 (41%), Gaps = 49/218 (22%)

Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231
           GR+E+L  G+WG+VCDD + +++A V CRQLG   A+       +  G GPI  D V C 
Sbjct: 44  GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103

Query: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVC---------SEHQSWRLTGGADR-------- 273
           G E+ L  C     G   C H ED G +C         SE  S  L     R        
Sbjct: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKP 163

Query: 274 -----------CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV---------- 312
                       EG VEV + G W  VCD  W  + ++V+C  LG  + V          
Sbjct: 164 ILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKV 223

Query: 313 -----ERPKGLPHSLSGRMYY-----SCNGEELTLSNC 340
                  PK    SL+ +  +     +C G E  ++NC
Sbjct: 224 WDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANC 261



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 68/212 (32%), Positives = 88/212 (41%), Gaps = 10/212 (4%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
           VRL +G+    G VEV +   W   C   W+  +A  VCR LG G A  A   A     L
Sbjct: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370

Query: 105 PPPPAAGNTSVAANATLAGAPALLCS--GAEWRLCEVVEHACRSDGRRARVTCAENRALR 162
            P   +         TL+  PAL  S  G +      V     + G + +V  A  R   
Sbjct: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGR--- 427

Query: 163 LVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF---TPG 219
            +   G    +VE+     WGSVC + W L +A V CRQLG G+A+ A     F   TP 
Sbjct: 428 -IPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486

Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGH 251
              +    V CSG E  L  C    G  +C H
Sbjct: 487 AQEVVMSGVRCSGTELALQQCQ-RHGPVHCSH 517



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 103/418 (24%), Positives = 137/418 (32%), Gaps = 78/418 (18%)

Query: 8   TGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCS-GTVEVRLEASW 66
           T  L   L G P P+ P  L T+              +RL    S    G +EV  +  W
Sbjct: 8   TLFLFLLLLGQPPPSRPQSLGTTK-------------LRLVGPESKPEEGRLEVLHQGQW 54

Query: 67  EPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPP---------------PPAAG 111
              C   +  + A   CR LG   A   +  A       P                    
Sbjct: 55  GTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGS 114

Query: 112 NTSVAANATLAGAPALLCSGAEWR--LCEVVEHACRSDGRRARVTCAENRALRLVDGGGA 169
           N    ++ + +    ++C     R  L E V +A    GRR      +            
Sbjct: 115 NGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPV 174

Query: 170 CAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQA----------------LPG 213
             G VE+   G W  VCD  W + ++ VVC  LG    V                     
Sbjct: 175 TEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSR 234

Query: 214 LHFTPGRGPIHRDQVNCSGAEAYLWDC------------PGLPGQHYC-------GHKED 254
           L     +      QV C G E ++ +C            P  PG  +         H   
Sbjct: 235 LKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP 294

Query: 255 AGAVCSEHQSW------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC 308
                    SW      RL  GA   EG+VEV     W TVCD  W    A V+C+ LG 
Sbjct: 295 PKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGF 354

Query: 309 GTAVERPKG--LPHSLSGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
           G+A E   G  L   L G ++ S   C G E TLS+C     + N C     A V C+
Sbjct: 355 GSAREALFGARLGQGL-GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 275 EGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---C 330
           EG++EV  +G W TVCD  +   EA V C+ LG   A+       +    G ++     C
Sbjct: 43  EGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRC 102

Query: 331 NGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370
            G E +L  C       + CS S    V+C   R    LS
Sbjct: 103 VGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLS 142


>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
          Length = 774

 Score =  130 bits (328), Expect = 3e-30
 Identities = 102/321 (31%), Positives = 143/321 (44%), Gaps = 39/321 (12%)

Query: 56  GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGG-----AEAASQLAPPTPELPPPPAA 110
           G VEV+   +W+  C   W ++ +  VC   G  G      +     A    +   P + 
Sbjct: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263

Query: 111 GNTSVAANATLAG-APALLCSGAEWRLCE---------VVEHACRSDG--RRARVTCAEN 158
             T   A+ +     P +     +   CE         V       DG  R  +    E 
Sbjct: 264 DCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQ 323

Query: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
             +RL  G     GRVE+L++GEWG+VCDD WDL  A VVCR+LG G A +A+ G     
Sbjct: 324 PLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 383

Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSE-----HQSWRLTGGADR 273
           G GPIH +++ C+G E  + DC        C H+EDAG  C+       +  RL GG + 
Sbjct: 384 GIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNP 443

Query: 274 CEGQVEVHFRG----VWNTVCDSEWYPSEAKVLCQSLGCGTAVERPK------GLPHS-- 321
            EG+VEV        VW  VC   W   EA V+C+ LG G A    +      G  +S  
Sbjct: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503

Query: 322 --LSGRMYYSCNGEELTLSNC 340
             +SG     C+G EL+L++C
Sbjct: 504 VVMSG---VKCSGTELSLAHC 521



 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 63/209 (30%), Positives = 81/209 (38%), Gaps = 43/209 (20%)

Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231
           GRVE+   G+WG+VCDD + +  AHVVCR+LG   A        +  G GPI  D ++C+
Sbjct: 70  GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTG--------------------- 269
           G EA L  C     G   C H ED G VCS+    R+ G                     
Sbjct: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDK---RIPGFKFDNSLINQIENLNIQVEDI 186

Query: 270 -----------GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC-GTAVERPKG 317
                           EG VEV     W  +CD  W    ++V+C   G  G      K 
Sbjct: 187 RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKV 246

Query: 318 LPHSLSGR------MYYSCNGEELTLSNC 340
                S R          C G E  +S+C
Sbjct: 247 YKMFASRRKQRYWPFSMDCTGTEAHISSC 275



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 98/369 (26%), Positives = 137/369 (37%), Gaps = 76/369 (20%)

Query: 56  GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPA-AGNTS 114
           G VEV  +  W   C   +   AA  VCR LG    EA S  A  +      P    N  
Sbjct: 70  GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGY--VEAKSWTASSSYGKGEGPIWLDNLH 127

Query: 115 VAAN-ATLAGAPALLCSGAEWRLCEVVEHACRSDGR-------RARVTCAENRALRLVD- 165
              N ATLA   +      + +  E V   C SD R        + +   EN  +++ D 
Sbjct: 128 CTGNEATLAACTSNGWGVTDCKHTEDVGVVC-SDKRIPGFKFDNSLINQIENLNIQVEDI 186

Query: 166 -----------GGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPG- 213
                            G VE+ E   W  +CD  W  +++ VVC   G        PG 
Sbjct: 187 RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG-------FPGE 239

Query: 214 ---------LHFTPGRGPIHRDQVNCSGAEAYLWDCP-----------------GLPGQH 247
                    +  +  +       ++C+G EA++  C                  GLP   
Sbjct: 240 RTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299

Query: 248 YC---------GHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298
            C         G      A   E    RL GGA   EG+VEV   G W TVCD +W    
Sbjct: 300 SCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVS 359

Query: 299 AKVLCQSLGCGTAVERPKG--LPHSLSGRMYYS---CNGEELTLSNCSWRFN-NSNLCSQ 352
           A V+C+ LG G+A E   G  L   + G ++ +   C G E ++ +C  +FN  S  C+ 
Sbjct: 360 ASVVCRELGFGSAKEAVTGSRLGQGI-GPIHLNEIQCTGNEKSIIDC--KFNAESQGCNH 416

Query: 353 SLAARVLCS 361
              A V C+
Sbjct: 417 EEDAGVRCN 425



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 73/233 (31%), Positives = 87/233 (37%), Gaps = 29/233 (12%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA---SQLAPPT 101
           VRL  G+    G VEV     W   C   WD  +A  VCR LG G A+ A   S+L    
Sbjct: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385

Query: 102 P--ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARV-TCAEN 158
               L      GN     +             AE + C   E A    G R         
Sbjct: 386 GPIHLNEIQCTGNEKSIIDCKF---------NAESQGCNHEEDA----GVRCNTPAMGLQ 432

Query: 159 RALRLVDGGGACAGRVEMLEHGE----WGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGL 214
           + LRL  G     GRVE+L        WG VC   W + +A VVCRQLG G+A  A    
Sbjct: 433 KKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQET 492

Query: 215 HFTPG---RGPIHRDQVNCSGAEAYLWDCPGLPGQHYC---GHKEDAGAVCSE 261
            +  G      +    V CSG E  L  C        C   G +  AG  CSE
Sbjct: 493 WYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSE 545



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 10/97 (10%)

Query: 275 EGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGR-------MY 327
           EG+VEV++ G W TVCD ++    A V+C+ LG    VE       S  G+         
Sbjct: 69  EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELG---YVEAKSWTASSSYGKGEGPIWLDN 125

Query: 328 YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364
             C G E TL+ C+        C  +    V+CS  R
Sbjct: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKR 162



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 40  GERLPVRLTNGSSSCSGTVEVRLEAS----WEPACGALWDSRAAEAVCRALGCGGAEAAS 95
           G +  +RL  G +   G VEV +E +    W   CG  W    A  VCR LG G A  A 
Sbjct: 430 GLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAF 489

Query: 96  Q 96
           Q
Sbjct: 490 Q 490


>gi|5031863 galectin 3 binding protein [Homo sapiens]
          Length = 585

 Score =  102 bits (254), Expect = 1e-21
 Identities = 52/101 (51%), Positives = 62/101 (61%), Gaps = 1/101 (0%)

Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220
           +RL DGG    GRVE+   G+WG+VCD+ WDL DA VVCR LG   A QAL    F  G 
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 221 GPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260
           GPI  D+V C+G EA L DC  L   +  C H+ DAG VC+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 17/115 (14%)

Query: 266 RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGR 325
           RL  G    +G+VE+ +RG W TVCD+ W  ++A V+C++LG   A +    L  +  G+
Sbjct: 25  RLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQ---ALGRAAFGQ 81

Query: 326 -------MYYSCNGEELTLSNC---SWRFNNSNLCSQSLAARVLC-SASRSLHNL 369
                      C G E +L++C    W  +N   C     A V+C + +RS H L
Sbjct: 82  GSGPIMLDEVQCTGTEASLADCKSLGWLKSN---CRHERDAGVVCTNETRSTHTL 133



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 20/50 (40%), Positives = 25/50 (50%)

Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94
          +RL +G ++  G VE+     W   C  LWD   A  VCRALG   A  A
Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQA 73


>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
          Length = 782

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 57/129 (44%), Positives = 72/129 (55%), Gaps = 10/129 (7%)

Query: 145 RSDGRRARVTCAENRA-----LRLVDGGGACAG--RVEMLEHGEWGSVCDDTWDLEDAHV 197
           R  GRR     + +RA     +RLV   G  +G  RVE+   G WG+VCDD+W++  A V
Sbjct: 652 RGGGRRRGRLNSASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAV 711

Query: 198 VCRQLGCGWAVQALPGLHFTPGRG-PIHRDQVNCSGAEAYLWDCP-GLPGQHYCGHKEDA 255
           VCRQLG  +AV+A+    F  G   PI  D V C+G E  L +C     G H C H EDA
Sbjct: 712 VCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDA 771

Query: 256 GAVCSEHQS 264
           G VCS HQ+
Sbjct: 772 GVVCS-HQN 779



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 5/97 (5%)

Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRM--- 326
           G     G+VEV   G W TVCD  W  S A V+C+ LG   AV   K       G +   
Sbjct: 680 GLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPIL 739

Query: 327 --YYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
                C G E  L  C      ++ C     A V+CS
Sbjct: 740 LDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 31/91 (34%), Positives = 37/91 (40%), Gaps = 12/91 (13%)

Query: 19  PSPAPPDQLNTS-----------SAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWE 67
           P PA P Q   S           ++ S  +  GE   VR   G SS SG VEV +   W 
Sbjct: 639 PRPARPTQQPGSRRGGGRRRGRLNSASRAFRDGEVRLVRPA-GLSSGSGRVEVFVGGRWG 697

Query: 68  PACGALWDSRAAEAVCRALGCGGAEAASQLA 98
             C   W+   A  VCR LG   A  A + A
Sbjct: 698 TVCDDSWNISGAAVVCRQLGFAYAVRAVKRA 728


>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
           sapiens]
          Length = 451

 Score = 86.3 bits (212), Expect = 8e-17
 Identities = 42/101 (41%), Positives = 55/101 (54%), Gaps = 1/101 (0%)

Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220
           +RLV G G   GRVE+L  G+WG++CDD W++    VVCR LG           HF  G 
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 221 GPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260
           GPI  ++V C G E+ + +C     G   C H EDAG  C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 4/125 (3%)

Query: 241 PGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK 300
           PG  G      ++ +G   +     RL GG+   EG+VE+   G W T+CD  W     +
Sbjct: 326 PGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQ 385

Query: 301 VLCQSLGC-GTAVERPKGLPHSLSGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAA 356
           V+C+SLG  G             +G ++ +   C G E ++  C  R   +  CS S  A
Sbjct: 386 VVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDA 445

Query: 357 RVLCS 361
            V C+
Sbjct: 446 GVTCT 450



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 20/54 (37%), Positives = 26/54 (48%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98
           VRL  GS    G VE+     W   C   W+ R  + VCR+LG  G +A  + A
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAA 403


>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
          Length = 495

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 43/103 (41%), Positives = 52/103 (50%), Gaps = 1/103 (0%)

Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220
           +RLV+G G   GRVE+     WG+VCDD WD +D  VVCR LG     +      F  G 
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 221 GPIHRDQVNCSGAEAYLWDCP-GLPGQHYCGHKEDAGAVCSEH 262
           G I  D V C G E  ++ C     G   CGH EDA   C+ H
Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCNRH 495



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 4/100 (4%)

Query: 266 RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SG 324
           RL  G+   EG+VEV+    W TVCD  W   +  V+C+ LG     E  +       +G
Sbjct: 394 RLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGTG 453

Query: 325 RMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
           R++    +C G E T+  CS+       C  +  A V C+
Sbjct: 454 RIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 21/54 (38%), Positives = 26/54 (48%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98
           +RL NGS    G VEV  +  W   C   WD +  + VCR LG  G E   + A
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTA 446


>gi|5803080 macrophage receptor with collagenous structure [Homo
           sapiens]
          Length = 520

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 41/97 (42%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 167 GGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGC--GWAVQALPGLHFTPGRGPIH 224
           G +  GR E+   G WG++CDD W   DA V CR LG   G A+  +       G G I 
Sbjct: 428 GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGA-----GTGQIW 482

Query: 225 RDQVNCSGAEAYLWDC-PGLPGQHYCGHKEDAGAVCS 260
            D V C G E+ LW C     G H C H+EDAG  CS
Sbjct: 483 LDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 250 GHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309
           G K + G       S R+ G ++R  G+ EV++ G W T+CD EW  S+A V C+ LG  
Sbjct: 409 GVKGEKGERGENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYS 466

Query: 310 TAVERPKGLPHSLSGRMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
               R      + +G+++     C G E TL +C+      + CS    A V CS
Sbjct: 467 KG--RALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519


>gi|166197668 CD5 molecule [Homo sapiens]
          Length = 495

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 85/313 (27%), Positives = 113/313 (36%), Gaps = 73/313 (23%)

Query: 46  RLTNGSSSCSGTVEVRLEASWEPACGALW--------DSRAAEAVCRALGCGGAEAASQL 97
           RLT  +S C G +EV L+  W   C   W        D   A  VC+ L CG       L
Sbjct: 36  RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCG---VPLSL 92

Query: 98  APPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRS-------DGRR 150
            P      P      +S+     L       CS +   +C  +   C           R 
Sbjct: 93  GPFLVTYTP-----QSSIICYGQLGSFSN--CSHSRNDMCHSLGLTCLEPQKTTPPTTRP 145

Query: 151 ARVTCAENRA---LRLV--DGGGACAGRVEMLEHGEWGSVC----DDTWDLEDAHVVCRQ 201
              T  E  A   L+LV   GG  CAG VE       G++     D T DLE  + +C  
Sbjct: 146 PPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLE--NFLCNN 203

Query: 202 LGCGWAVQALP----GLHFTPGRGPIHR--------DQVNCSGAEAYLWDCPGLPGQHYC 249
           L CG  ++ LP    G    PG    H+           +C+  E             +C
Sbjct: 204 LQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLE-------------HC 250

Query: 250 GHK---EDAGAV----CSEHQ---SWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEA 299
             K   + +G V    CS  Q     RL GG+  CEG VEV     W  +CDS    S  
Sbjct: 251 FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSL 310

Query: 300 K--VLCQSLGCGT 310
           +   +C+   CG+
Sbjct: 311 RWEEVCREQQCGS 323



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 16/105 (15%)

Query: 257 AVCSEHQSW-------RLTGGADRCEGQVEVHFRGVWNTVCDSEW--------YPSEAKV 301
           A C    SW       RLT    +C+GQ+EV+ +  W+ VC   W         PS+A  
Sbjct: 20  ASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASK 79

Query: 302 LCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNN 346
           +CQ L CG  +     L  + + +    C G+  + SNCS   N+
Sbjct: 80  VCQRLNCGVPLSLGPFLV-TYTPQSSIICYGQLGSFSNCSHSRND 123



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 2/50 (4%)

Query: 46  RLTNGSSSCSGTVEVRLEASWEPAC--GALWDSRAAEAVCRALGCGGAEA 93
           RL  GSS C GTVEVR  A W   C   +   S   E VCR   CG   +
Sbjct: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326


>gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2
           [Homo sapiens]
          Length = 387

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 41/186 (22%), Positives = 66/186 (35%), Gaps = 20/186 (10%)

Query: 467 PIQVQAPPPEDSDSGSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSR--FQMPP 524
           P+  Q PP +  +       +HY    QPP+ +    N   H +   ++   R   Q PP
Sbjct: 204 PMMHQQPPSQQYNMPQGGG-QHYQ-GQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPP 261

Query: 525 LE-EGLEELHASHIPTANPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPW 583
            +  G E+ +         G     P  +  QY+P  NS+            P+   PP 
Sbjct: 262 QQYSGQEDYYGDQYSHGGQG----PPEGMNQQYYPDGNSQYGQQQDAYQGPPPQQGYPPQ 317

Query: 584 NPQVFSSERSSFLEQPPNLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQP----PPQPP 639
             Q    +     +Q       G  P+     P   +     G+ Y  ++P    PPQPP
Sbjct: 318 QQQYPGQQGYPGQQQ-------GYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPP 370

Query: 640 SEEQFG 645
            +  +G
Sbjct: 371 QQRPYG 376


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 16/53 (30%), Positives = 30/53 (56%)

Query: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQL 97
           VR  NG+++ +G V  R+++ W  AC   W ++ +  VC+ LG G   ++  +
Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPI 730



 Score = 33.1 bits (74), Expect = 0.85
 Identities = 23/92 (25%), Positives = 31/92 (33%), Gaps = 13/92 (14%)

Query: 222 PIHRDQVNCSGAEAYLWDCPGLPGQHYCG---HKEDAGAVCSEHQSWRLTGGADRCEGQV 278
           P   D   C   E        +P  + C    H ED      E    R   G     G V
Sbjct: 642 PCKADHFQCKNGEC-------VPLVNLCDGHLHCEDGS---DEADCVRFFNGTTNNNGLV 691

Query: 279 EVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGT 310
               + +W+T C   W    +  +CQ LG G+
Sbjct: 692 RFRIQSIWHTACAENWTTQISNDVCQLLGLGS 723


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 40/167 (23%), Positives = 60/167 (35%), Gaps = 10/167 (5%)

Query: 500 TTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPP--SLGPQYH 557
           T +YN Q      ++   S  Q PP +    +      P + P    +  P  S  P   
Sbjct: 468 TPYYNQQSPHPQQQQPPYS--QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP 525

Query: 558 PRSNSESSTSSGEDYCNSPKSKLPPWN-PQVFSSERSSFLEQPPNLELAGTQPAFSAGPP 616
           P   S +   S +          PP++ PQ     +S + +Q P      T    +A P 
Sbjct: 526 PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA----QSPYQQQQPQQPAPSTLSQQAAYPQ 581

Query: 617 ADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDNDDYD 663
                S  +    Q F PPPQ  S++ FG   S +P   S+     D
Sbjct: 582 PQSQQSQQTAYSQQRF-PPPQELSQDSFGSQASSAPSMTSSKGGQED 627


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 40/167 (23%), Positives = 60/167 (35%), Gaps = 10/167 (5%)

Query: 500 TTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPP--SLGPQYH 557
           T +YN Q      ++   S  Q PP +    +      P + P    +  P  S  P   
Sbjct: 468 TPYYNQQSPHPQQQQPPYS--QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP 525

Query: 558 PRSNSESSTSSGEDYCNSPKSKLPPWN-PQVFSSERSSFLEQPPNLELAGTQPAFSAGPP 616
           P   S +   S +          PP++ PQ     +S + +Q P      T    +A P 
Sbjct: 526 PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA----QSPYQQQQPQQPAPSTLSQQAAYPQ 581

Query: 617 ADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDNDDYD 663
                S  +    Q F PPPQ  S++ FG   S +P   S+     D
Sbjct: 582 PQSQQSQQTAYSQQRF-PPPQELSQDSFGSQASSAPSMTSSKGGQED 627


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 42/163 (25%), Positives = 61/163 (37%), Gaps = 26/163 (15%)

Query: 515 VQQSRFQMPP------LEEGLEELHAS--HIPTANPGH---CITDPPSLGPQYHPRSN-S 562
           +QQ   Q P       L + L+++H +  H P   P         P  L PQ   +   S
Sbjct: 270 IQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS 329

Query: 563 ESSTSSGEDYCNSPKSKL---------PPWNPQVFSSERSSFLEQPPNLELAGTQPAFSA 613
           ++    G+     P  K          PP  PQV   + +    Q   +   G Q + S+
Sbjct: 330 QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSS 389

Query: 614 GPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDS 656
            P     S     +  Q+  PPPQP  +     PG PS QP+S
Sbjct: 390 LPMLSSPSPGQQVQTPQSMPPPPQPSPQ-----PGQPSSQPNS 427


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 46/200 (23%), Positives = 65/200 (32%), Gaps = 14/200 (7%)

Query: 454  PVPIT-IPKEVFMLPIQVQAPPPEDSDSGSDSDYEHYDFSAQPPVALTTFYNSQRHRVTD 512
            P P++ +P  V  +  Q   PP   +           + + Q P A+       + + + 
Sbjct: 852  PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA---KPKWQPSS 908

Query: 513  EEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPPSLGPQYHPRSNSESSTSSGEDY 572
              V    F  PP E  L        P   P      PP   P   P  +   S       
Sbjct: 909  IPVPSPDFPPPPPESSLV------FPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSK 962

Query: 573  CNSPKSKLPPWNPQVFSSERSSFLEQPPNLELAGTQPAFSAGPPADDSSSTSSGEWYQNF 632
             +SP  K PP  PQ  SS +SS   + P  +        S   P  +S S S     +  
Sbjct: 963  TSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK----ETL 1018

Query: 633  QPPPQPPSEEQFGCPGSPSP 652
             PP  PP   +    G   P
Sbjct: 1019 PPPAAPPKPGKLNLSGVNLP 1038



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 35/130 (26%), Positives = 47/130 (36%), Gaps = 23/130 (17%)

Query: 534 ASHIPTANPGHCITDPPSLGPQYHPRSNSESSTSSGEDYC-NSPKSKLPPWNPQVFSSER 592
           AS+IP + P    T P  + P   P+  S         +C   P S L P  P V     
Sbjct: 821 ASYIPPSPP----TPPVPVPPPTLPKQQS---------FCAKPPPSPLSPV-PSVVKQIA 866

Query: 593 SSFLEQP--PNLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQP------PPQPPSEEQF 644
           S F   P  P +E    +P  +   P    +  +  +W  +  P      PP PP     
Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926

Query: 645 GCPGSPSPQP 654
             P  PSP P
Sbjct: 927 FPPPPPSPVP 936


>gi|15529996 son of sevenless homolog 1 [Homo sapiens]
          Length = 1333

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 49/193 (25%), Positives = 73/193 (37%), Gaps = 24/193 (12%)

Query: 441  LPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPP---PEDSDSGSDSDY---EHYDFS-A 493
            +  T+P G  S     I++ K    +P+    PP   PE + + S       +H D   A
Sbjct: 1122 IQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPA 1181

Query: 494  QPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPPSLG 553
             PP   T+   S R+ ++D        + PPL    E +    + +++P H    PP LG
Sbjct: 1182 IPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLH--LQPPPLG 1239

Query: 554  PQYHPRSNSESSTSSGEDYCNSPK--SKLPPWNPQVFSSERSSFLEQPPNLELAGTQPAF 611
                     + S      + NSP   +  PP  P    + R   L  PP  +        
Sbjct: 1240 ---------KKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRR--HLPSPPLTQEVDLHSI- 1287

Query: 612  SAGPPADDSSSTS 624
             AGPP     STS
Sbjct: 1288 -AGPPVPPRQSTS 1299


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,954,105
Number of Sequences: 37866
Number of extensions: 1934998
Number of successful extensions: 10484
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 295
Number of HSP's that attempted gapping in prelim test: 8916
Number of HSP's gapped (non-prelim): 1557
length of query: 668
length of database: 18,247,518
effective HSP length: 109
effective length of query: 559
effective length of database: 14,120,124
effective search space: 7893149316
effective search space used: 7893149316
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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