BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194018748 CD6 molecule [Homo sapiens] (668 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194018748 CD6 molecule [Homo sapiens] 1402 0.0 gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 255 1e-67 gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 250 3e-66 gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 247 3e-65 gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 244 2e-64 gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 241 2e-63 gi|44889963 CD163 antigen isoform b [Homo sapiens] 201 1e-51 gi|44662834 CD163 antigen isoform a [Homo sapiens] 201 1e-51 gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H... 199 7e-51 gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] 192 1e-48 gi|5174411 CD5 molecule-like [Homo sapiens] 191 2e-48 gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 179 6e-45 gi|18152779 scavenger receptor cysteine rich domain containing, ... 174 2e-43 gi|4506143 neurotrypsin precursor [Homo sapiens] 170 3e-42 gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] 135 1e-31 gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] 134 3e-31 gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] 130 3e-30 gi|5031863 galectin 3 binding protein [Homo sapiens] 102 1e-21 gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens] 89 1e-17 gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo... 86 8e-17 gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] 84 4e-16 gi|5803080 macrophage receptor with collagenous structure [Homo ... 75 3e-13 gi|166197668 CD5 molecule [Homo sapiens] 62 2e-09 gi|56117844 synovial sarcoma translocation, chromosome 18 isofor... 42 0.001 gi|223942069 enterokinase precursor [Homo sapiens] 42 0.002 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 42 0.002 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 42 0.002 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 41 0.004 gi|47132519 Ras association and pleckstrin homology domains 1 is... 40 0.009 gi|15529996 son of sevenless homolog 1 [Homo sapiens] 39 0.012 >gi|194018748 CD6 molecule [Homo sapiens] Length = 668 Score = 1402 bits (3628), Expect = 0.0 Identities = 668/668 (100%), Positives = 668/668 (100%) Query: 1 MWLFFGITGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEV 60 MWLFFGITGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEV Sbjct: 1 MWLFFGITGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEV 60 Query: 61 RLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANAT 120 RLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANAT Sbjct: 61 RLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANAT 120 Query: 121 LAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHG 180 LAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHG Sbjct: 121 LAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHG 180 Query: 181 EWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC 240 EWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC Sbjct: 181 EWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDC 240 Query: 241 PGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK 300 PGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK Sbjct: 241 PGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK 300 Query: 301 VLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360 VLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC Sbjct: 301 VLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360 Query: 361 SASRSLHNLSTPEVPASVQTVTIESSVTVKIENKESRELMLLIPSIVLGILLLGSLIFIA 420 SASRSLHNLSTPEVPASVQTVTIESSVTVKIENKESRELMLLIPSIVLGILLLGSLIFIA Sbjct: 361 SASRSLHNLSTPEVPASVQTVTIESSVTVKIENKESRELMLLIPSIVLGILLLGSLIFIA 420 Query: 421 FILLRIKGKYALPVMVNHQHLPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPPPEDSDS 480 FILLRIKGKYALPVMVNHQHLPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPPPEDSDS Sbjct: 421 FILLRIKGKYALPVMVNHQHLPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPPPEDSDS 480 Query: 481 GSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTA 540 GSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTA Sbjct: 481 GSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTA 540 Query: 541 NPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPWNPQVFSSERSSFLEQPP 600 NPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPWNPQVFSSERSSFLEQPP Sbjct: 541 NPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPWNPQVFSSERSSFLEQPP 600 Query: 601 NLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDND 660 NLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDND Sbjct: 601 NLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDND 660 Query: 661 DYDDISAA 668 DYDDISAA Sbjct: 661 DYDDISAA 668 >gi|148539844 deleted in malignant brain tumors 1 isoform c precursor [Homo sapiens] Length = 2403 Score = 255 bits (651), Expect = 1e-67 Identities = 165/423 (39%), Positives = 209/423 (49%), Gaps = 55/423 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + P L +RL NG C G VEV SW Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 386 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 431 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAE----------------NRALRLVDGG 167 CSG E L + H C+ A V C++ + ALRLV+GG Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSDTLPTITLPASTVGSESSLALRLVNGG 490 Query: 168 GACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQ 227 C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D Sbjct: 491 DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDD 550 Query: 228 VNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS---WRLTGGADRCEGQVEVHFR 283 V CSG E+YLW CP H CGH EDAG +CS +S RL G DRC+G+VEV +R Sbjct: 551 VRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYR 610 Query: 284 GVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSN 339 G W TVCD W ++A V+C+ LGCG A P SG + C+G E L + Sbjct: 611 GSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 670 Query: 340 CSWRFNNSNLCSQSLAARVLCSASRSL-----HNLSTPEVPASVQTVTIESSVTVKIENK 394 C S+ C A V+CSA++S LST +P S TV ESS+T+++ N Sbjct: 671 CPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPS--TVGSESSLTLRLVNG 728 Query: 395 ESR 397 R Sbjct: 729 SDR 731 Score = 243 bits (619), Expect = 5e-64 Identities = 163/450 (36%), Positives = 204/450 (45%), Gaps = 80/450 (17%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ + P+P+P D TS A + P L +RL NG C G VEV SW Sbjct: 819 GVICSVSQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 875 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 876 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 920 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157 CSG E L + H C+ A V C+ Sbjct: 921 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 979 Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217 + ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F Sbjct: 980 SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 1039 Query: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W--- 265 G GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 1040 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 1099 Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312 RL G DRC+G+VEV +RG W TVCD W ++A V+C+ LGCG A+ Sbjct: 1100 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 1159 Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368 P SG + C+G E L +C S+ C A V+CSAS+S Sbjct: 1160 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1219 Query: 369 LSTPEVPAS-VQTVTIESSVTVKIENKESR 397 S P S T ESS+ +++ N R Sbjct: 1220 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1249 Score = 241 bits (615), Expect = 2e-63 Identities = 160/450 (35%), Positives = 201/450 (44%), Gaps = 78/450 (17%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A +P P D L+T + L +RL NGS C G VEV SW Sbjct: 688 GVICSAAQSRSTPRP-DTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGT 746 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A + A GN + + Sbjct: 747 VCDDSWDTNDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 791 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 792 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSL 850 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA A F G Sbjct: 851 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 910 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSW------------- 265 GPI D V CSG E+YLW CP H C H EDAG +CS SW Sbjct: 911 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 970 Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312 RL G DRC+G+VEV ++G W TVCD W ++A V+C+ LGCG A+ Sbjct: 971 PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1030 Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368 P SG + C+G E L +C S+ C S A V+CSAS+S Sbjct: 1031 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1090 Query: 369 LSTPEVPAS-VQTVTIESSVTVKIENKESR 397 S P S T ESS+ +++ N R Sbjct: 1091 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1120 Score = 239 bits (611), Expect = 5e-63 Identities = 163/448 (36%), Positives = 202/448 (45%), Gaps = 78/448 (17%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 1079 GVICSASQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1135 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 1136 VCDDYWDTNDANVVCRQLGCGWAMSAP---------------GNARFGQGSGPIVLDDVR 1180 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 1181 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1239 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA A F G Sbjct: 1240 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1299 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 1300 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1359 Query: 266 -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314 RL G DRC+G+VEV +RG W TVCD W ++A V+C+ LGCG A Sbjct: 1360 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1419 Query: 315 PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370 P SG + C+G E L +C S+ C A V+CSAS+S S Sbjct: 1420 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1479 Query: 371 TPEVPAS-VQTVTIESSVTVKIENKESR 397 P S T ES++ +++ N R Sbjct: 1480 PDTWPTSRASTAGSESTLALRLVNGGDR 1507 Score = 238 bits (606), Expect = 2e-62 Identities = 155/411 (37%), Positives = 197/411 (47%), Gaps = 57/411 (13%) Query: 39 PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA---- 94 P L +RL NG C G VEV SW C WD+ A VCR LGCG A +A Sbjct: 586 PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 645 Query: 95 --SQLAPPTPELPPPPAAGNTS----------VAANATLAGAPALLCSGAEWRLCEVVEH 142 Q + P L +G+ S ++ N ++CS A+ R + Sbjct: 646 RFGQGSGPIV-LDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT 704 Query: 143 ACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202 + V + LRLV+G C GRVE+L G WG+VCDD+WD DA+VVCRQL Sbjct: 705 LSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 764 Query: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSE 261 GCGWA A F G GPI D V CSG E+YLW CP H CGH EDAG +CS Sbjct: 765 GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 824 Query: 262 HQS--------W----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPS 297 QS W RL G DRC+G+VEV +RG W TVCD W S Sbjct: 825 SQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 884 Query: 298 EAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQS 353 +A V+C+ LGCG A P SG + C+G E L +C S+ C S Sbjct: 885 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 944 Query: 354 LAARVLCSASRSLHNLSTPEVPASVQTVTI-------ESSVTVKIENKESR 397 A V+CSA+ H+ STP P ++ T+T+ ESS+ +++ N R Sbjct: 945 EDAGVICSAA---HSWSTPS-PDTLPTITLPASTVGSESSLALRLVNGGDR 991 Score = 235 bits (600), Expect = 9e-62 Identities = 163/452 (36%), Positives = 204/452 (45%), Gaps = 84/452 (18%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 1208 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1264 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 1265 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1309 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 1310 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1368 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA A F G Sbjct: 1369 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1428 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 1429 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 1488 Query: 266 -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314 RL G DRC G+VEV ++G W TVCD W ++A V+C+ LGCG A+ Sbjct: 1489 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1548 Query: 315 PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL---- 366 P SG + C+G E L +C S+ C A V+CSA++S Sbjct: 1549 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1608 Query: 367 -HNLSTPEVPASVQTVTIESSVTVKIENKESR 397 T +PA TV ESS+ +++ N R Sbjct: 1609 PDTWLTTNLPA--LTVGSESSLALRLVNGGDR 1638 Score = 234 bits (598), Expect = 1e-61 Identities = 160/430 (37%), Positives = 195/430 (45%), Gaps = 85/430 (19%) Query: 30 SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88 S+ ES + E + L +RL NG C G VE+ SW C WD+ A VCR LGC Sbjct: 86 STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145 Query: 89 GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143 G A + A GN + + CSG E L + H Sbjct: 146 GWAMS---------------APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190 Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176 C G A V C+ + ALRLV+GG C GRVE+ Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249 Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236 L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CSG E+Y Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309 Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271 LW CP H CGH EDAG +CS QS W RL G Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 369 Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329 DRC+G+VEV +RG W TVCD W S+A V+C+ LGCG A P SG + Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429 Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSV 387 C+G E L +C S+ C S A V+CS L T +PAS TV ESS+ Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS-----DTLPTITLPAS--TVGSESSL 482 Query: 388 TVKIENKESR 397 +++ N R Sbjct: 483 ALRLVNGGDR 492 Score = 232 bits (591), Expect = 1e-60 Identities = 152/416 (36%), Positives = 190/416 (45%), Gaps = 79/416 (18%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 1337 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1393 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 1394 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1438 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 1439 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTL 1497 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G Sbjct: 1498 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 1557 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 1558 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1617 Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312 RL G DRC G+VEV +RG W TVCD W ++A V+C+ LGCG A+ Sbjct: 1618 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1677 Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364 P SG + C+G E L +C + ++ C A V+CSA++ Sbjct: 1678 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1733 Score = 200 bits (508), Expect = 4e-51 Identities = 133/344 (38%), Positives = 164/344 (47%), Gaps = 44/344 (12%) Query: 95 SQLAPPTPELPPPPAAGNT----SVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR 150 + L P L P A G+ S + G+P L S E V E + Sbjct: 31 ASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLE---STVAEGSLIPSEST 87 Query: 151 ARVTCAENR----ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206 T AE ALRLV+G G C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGW Sbjct: 88 LESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGW 147 Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ-- 263 A+ A F G GPI D V CSG E+YLW CP H CGH EDAG +CS Q Sbjct: 148 AMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQ 207 Query: 264 ------SW-------------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298 SW RL G DRC G+VEV +RG W TVCD W ++ Sbjct: 208 STLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTND 267 Query: 299 AKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSL 354 A V+C+ LGCG A+ P SG + C+G E L +C ++ C S Sbjct: 268 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSE 327 Query: 355 AARVLCSASRSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397 A V+CSA +S S P S T ESS+ +++ N R Sbjct: 328 DAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR 371 Score = 180 bits (456), Expect = 4e-45 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV + SW Sbjct: 1466 GVICSASQSQPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 1522 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 1523 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 1581 Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172 ++ N ++CS A+ + + ++ V + ALRLV+GG C G Sbjct: 1582 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1641 Query: 173 RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232 RVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D V CSG Sbjct: 1642 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1701 Query: 233 AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291 E+YLW CP H CGH EDAG +CS Q N+ Sbjct: 1702 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1739 Query: 292 SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342 W+P+ S CG + G S S YY N + C W Sbjct: 1740 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1784 Score = 117 bits (292), Expect = 4e-26 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Query: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 R + L G CAGRVE+ G WG+VCDD+W +++A VVCRQLGCG AV AL +F Sbjct: 1874 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1933 Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260 G GPI D V CSG E+ LW C H C H+EDAG +CS Sbjct: 1934 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1976 Score = 66.6 bits (161), Expect = 7e-11 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%) Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328 C G+VE++ G W TVCD W EA+V+C+ LGCG AV S G Y+ Sbjct: 1885 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1936 Query: 329 -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372 C+G E TL C R S+ C+ A V+CS ++LSTP Sbjct: 1937 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1983 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 45 VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94 +RL N +SS C+G VE+ +W C W + AE VCR LGCG A +A Sbjct: 1873 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1925 >gi|148539842 deleted in malignant brain tumors 1 isoform b precursor [Homo sapiens] Length = 2413 Score = 250 bits (639), Expect = 3e-66 Identities = 165/433 (38%), Positives = 208/433 (48%), Gaps = 65/433 (15%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + P L +RL NG C G VEV SW Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 386 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 431 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157 CSG E L + H C+ A V C+ Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 490 Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217 + ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F Sbjct: 491 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG 550 Query: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS---WRLTGGADR 273 G GPI D V CSG E+YLW CP H CGH EDAG +CS +S RL G DR Sbjct: 551 QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDR 610 Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS--- 329 C+G+VEV +RG W TVCD W ++A V+C+ LGCG A P SG + Sbjct: 611 CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVR 670 Query: 330 CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLSTPEVPASVQTVTIE 384 C+G E L +C S+ C A V+CSA++S LST +P S TV E Sbjct: 671 CSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPS--TVGSE 728 Query: 385 SSVTVKIENKESR 397 SS+T+++ N R Sbjct: 729 SSLTLRLVNGSDR 741 Score = 243 bits (619), Expect = 5e-64 Identities = 163/450 (36%), Positives = 204/450 (45%), Gaps = 80/450 (17%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ + P+P+P D TS A + P L +RL NG C G VEV SW Sbjct: 829 GVICSVSQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 885 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 886 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 930 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157 CSG E L + H C+ A V C+ Sbjct: 931 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 989 Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217 + ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F Sbjct: 990 SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 1049 Query: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W--- 265 G GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 1050 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 1109 Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312 RL G DRC+G+VEV +RG W TVCD W ++A V+C+ LGCG A+ Sbjct: 1110 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 1169 Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368 P SG + C+G E L +C S+ C A V+CSAS+S Sbjct: 1170 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1229 Query: 369 LSTPEVPAS-VQTVTIESSVTVKIENKESR 397 S P S T ESS+ +++ N R Sbjct: 1230 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1259 Score = 241 bits (615), Expect = 2e-63 Identities = 160/450 (35%), Positives = 201/450 (44%), Gaps = 78/450 (17%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A +P P D L+T + L +RL NGS C G VEV SW Sbjct: 698 GVICSAAQSRSTPRP-DTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGT 756 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A + A GN + + Sbjct: 757 VCDDSWDTNDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 801 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 802 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSL 860 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA A F G Sbjct: 861 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 920 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSW------------- 265 GPI D V CSG E+YLW CP H C H EDAG +CS SW Sbjct: 921 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 980 Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312 RL G DRC+G+VEV ++G W TVCD W ++A V+C+ LGCG A+ Sbjct: 981 PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1040 Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368 P SG + C+G E L +C S+ C S A V+CSAS+S Sbjct: 1041 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100 Query: 369 LSTPEVPAS-VQTVTIESSVTVKIENKESR 397 S P S T ESS+ +++ N R Sbjct: 1101 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1130 Score = 239 bits (611), Expect = 5e-63 Identities = 163/448 (36%), Positives = 202/448 (45%), Gaps = 78/448 (17%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 1089 GVICSASQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1145 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 1146 VCDDYWDTNDANVVCRQLGCGWAMSAP---------------GNARFGQGSGPIVLDDVR 1190 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 1191 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1249 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA A F G Sbjct: 1250 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1309 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 1310 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1369 Query: 266 -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314 RL G DRC+G+VEV +RG W TVCD W ++A V+C+ LGCG A Sbjct: 1370 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1429 Query: 315 PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370 P SG + C+G E L +C S+ C A V+CSAS+S S Sbjct: 1430 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1489 Query: 371 TPEVPAS-VQTVTIESSVTVKIENKESR 397 P S T ES++ +++ N R Sbjct: 1490 PDTWPTSRASTAGSESTLALRLVNGGDR 1517 Score = 238 bits (608), Expect = 1e-62 Identities = 161/437 (36%), Positives = 201/437 (45%), Gaps = 89/437 (20%) Query: 30 SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88 S+ ES + E + L +RL NG C G VE+ SW C WD+ A VCR LGC Sbjct: 86 STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145 Query: 89 GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143 G A +A GN + + CSG E L + H Sbjct: 146 GWAMSAP---------------GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190 Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176 C G A V C+ + ALRLV+GG C GRVE+ Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249 Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236 L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CSG E+Y Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309 Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271 LW CP H CGH EDAG +CS QS W RL G Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 369 Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329 DRC+G+VEV +RG W TVCD W S+A V+C+ LGCG A P SG + Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429 Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTI---- 383 C+G E L +C S+ C S A V+CSA+ H+ STP P ++ T+T+ Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA---HSWSTPS-PDTLPTITLPAST 485 Query: 384 ---ESSVTVKIENKESR 397 ESS+ +++ N R Sbjct: 486 VGSESSLALRLVNGGDR 502 Score = 238 bits (606), Expect = 2e-62 Identities = 155/411 (37%), Positives = 197/411 (47%), Gaps = 57/411 (13%) Query: 39 PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA---- 94 P L +RL NG C G VEV SW C WD+ A VCR LGCG A +A Sbjct: 596 PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 655 Query: 95 --SQLAPPTPELPPPPAAGNTS----------VAANATLAGAPALLCSGAEWRLCEVVEH 142 Q + P L +G+ S ++ N ++CS A+ R + Sbjct: 656 RFGQGSGPIV-LDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT 714 Query: 143 ACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202 + V + LRLV+G C GRVE+L G WG+VCDD+WD DA+VVCRQL Sbjct: 715 LSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 774 Query: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSE 261 GCGWA A F G GPI D V CSG E+YLW CP H CGH EDAG +CS Sbjct: 775 GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 834 Query: 262 HQS--------W----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPS 297 QS W RL G DRC+G+VEV +RG W TVCD W S Sbjct: 835 SQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 894 Query: 298 EAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQS 353 +A V+C+ LGCG A P SG + C+G E L +C S+ C S Sbjct: 895 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 954 Query: 354 LAARVLCSASRSLHNLSTPEVPASVQTVTI-------ESSVTVKIENKESR 397 A V+CSA+ H+ STP P ++ T+T+ ESS+ +++ N R Sbjct: 955 EDAGVICSAA---HSWSTPS-PDTLPTITLPASTVGSESSLALRLVNGGDR 1001 Score = 235 bits (600), Expect = 9e-62 Identities = 163/452 (36%), Positives = 204/452 (45%), Gaps = 84/452 (18%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 1218 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1274 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 1275 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1319 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 1320 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1378 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA A F G Sbjct: 1379 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1438 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 1439 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 1498 Query: 266 -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314 RL G DRC G+VEV ++G W TVCD W ++A V+C+ LGCG A+ Sbjct: 1499 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1558 Query: 315 PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL---- 366 P SG + C+G E L +C S+ C A V+CSA++S Sbjct: 1559 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1618 Query: 367 -HNLSTPEVPASVQTVTIESSVTVKIENKESR 397 T +PA TV ESS+ +++ N R Sbjct: 1619 PDTWLTTNLPA--LTVGSESSLALRLVNGGDR 1648 Score = 232 bits (591), Expect = 1e-60 Identities = 152/416 (36%), Positives = 190/416 (45%), Gaps = 79/416 (18%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 1347 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1403 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 1404 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1448 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 1449 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTL 1507 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G Sbjct: 1508 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 1567 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 1568 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1627 Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312 RL G DRC G+VEV +RG W TVCD W ++A V+C+ LGCG A+ Sbjct: 1628 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1687 Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364 P SG + C+G E L +C + ++ C A V+CSA++ Sbjct: 1688 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1743 Score = 200 bits (508), Expect = 4e-51 Identities = 133/344 (38%), Positives = 164/344 (47%), Gaps = 44/344 (12%) Query: 95 SQLAPPTPELPPPPAAGNT----SVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR 150 + L P L P A G+ S + G+P L S E V E + Sbjct: 31 ASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLE---STVAEGSLIPSEST 87 Query: 151 ARVTCAENR----ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206 T AE ALRLV+G G C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGW Sbjct: 88 LESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGW 147 Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ-- 263 A+ A F G GPI D V CSG E+YLW CP H CGH EDAG +CS Q Sbjct: 148 AMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQ 207 Query: 264 ------SW-------------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298 SW RL G DRC G+VEV +RG W TVCD W ++ Sbjct: 208 STLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTND 267 Query: 299 AKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSL 354 A V+C+ LGCG A+ P SG + C+G E L +C ++ C S Sbjct: 268 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSE 327 Query: 355 AARVLCSASRSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397 A V+CSA +S S P S T ESS+ +++ N R Sbjct: 328 DAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR 371 Score = 180 bits (456), Expect = 4e-45 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV + SW Sbjct: 1476 GVICSASQSQPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 1532 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 1533 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 1591 Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172 ++ N ++CS A+ + + ++ V + ALRLV+GG C G Sbjct: 1592 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1651 Query: 173 RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232 RVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D V CSG Sbjct: 1652 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1711 Query: 233 AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291 E+YLW CP H CGH EDAG +CS Q N+ Sbjct: 1712 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1749 Query: 292 SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342 W+P+ S CG + G S S YY N + C W Sbjct: 1750 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1794 Score = 117 bits (292), Expect = 4e-26 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Query: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 R + L G CAGRVE+ G WG+VCDD+W +++A VVCRQLGCG AV AL +F Sbjct: 1884 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1943 Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260 G GPI D V CSG E+ LW C H C H+EDAG +CS Sbjct: 1944 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986 Score = 66.6 bits (161), Expect = 7e-11 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%) Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328 C G+VE++ G W TVCD W EA+V+C+ LGCG AV S G Y+ Sbjct: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1946 Query: 329 -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372 C+G E TL C R S+ C+ A V+CS ++LSTP Sbjct: 1947 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1993 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 45 VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94 +RL N +SS C+G VE+ +W C W + AE VCR LGCG A +A Sbjct: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1935 >gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] Length = 1788 Score = 247 bits (630), Expect = 3e-65 Identities = 162/441 (36%), Positives = 208/441 (47%), Gaps = 59/441 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A +P+P D L T + + L +RL NG C G VEV SW Sbjct: 459 GVICSAAHSWSTPSP-DTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPE---------LPPPPAAGNTS----- 114 C WD+ A VCR LGCG A LAP L +GN S Sbjct: 518 VCDDSWDTNDANVVCRQLGCGWA----MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSC 573 Query: 115 -----VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCA---ENRALRLVDG 166 ++ N + ++CS +W + + S A TC + ALRLV+G Sbjct: 574 PHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSS--HALQTCKGPESSLALRLVNG 631 Query: 167 GGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRD 226 G C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA A F G GPI D Sbjct: 632 GDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD 691 Query: 227 QVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W------------ 265 V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 692 DVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSES 751 Query: 266 ----RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHS 321 RL G DRC+G+VEV ++G W TVCD W ++A V+C+ LGCG A+ P Sbjct: 752 SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 811 Query: 322 L-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPAS 377 SG + C+G E L +C S+ C S A V+CSAS+S S P S Sbjct: 812 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 871 Query: 378 -VQTVTIESSVTVKIENKESR 397 T ES++ +++ N R Sbjct: 872 RASTAGSESTLALRLVNGGDR 892 Score = 240 bits (613), Expect = 3e-63 Identities = 162/439 (36%), Positives = 208/439 (47%), Gaps = 55/439 (12%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +AL P+P P +S A P L +RL NG C G VEV SW Sbjct: 590 GVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGT 649 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 650 VCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPNN 708 Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172 ++ N ++CS A+ R + S A + ALRLV+GG C G Sbjct: 709 GWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAG--SESSLALRLVNGGDRCQG 766 Query: 173 RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232 RVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D V CSG Sbjct: 767 RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 826 Query: 233 AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RL 267 E+YLW CP H CGH EDAG +CS QS W RL Sbjct: 827 HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRL 886 Query: 268 TGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRM 326 G DRC G+VEV ++G W TVCD W ++A V+C+ LGCG A+ P SG + Sbjct: 887 VNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPI 946 Query: 327 YYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLSTPEVPASV 378 C+G E L +C S+ C A V+CSA++S T +PA Sbjct: 947 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPA-- 1004 Query: 379 QTVTIESSVTVKIENKESR 397 TV ESS+ +++ N R Sbjct: 1005 LTVGSESSLALRLVNGGDR 1023 Score = 238 bits (608), Expect = 1e-62 Identities = 161/437 (36%), Positives = 201/437 (45%), Gaps = 89/437 (20%) Query: 30 SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88 S+ ES + E + L +RL NG C G VE+ SW C WD+ A VCR LGC Sbjct: 86 STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145 Query: 89 GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143 G A + A GN + + CSG E L + H Sbjct: 146 GWAMS---------------APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190 Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176 C G A V C+ + ALRLV+GG C GRVE+ Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249 Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236 L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CSG E+Y Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309 Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271 LW CP H CGH EDAG +CS QS W RL G Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGG 369 Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329 DRC+G+VEV +RG W TVCD W S+A V+C+ LGCG A P SG + Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429 Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTI---- 383 C+G E L +C S+ C S A V+CSA+ H+ STP P ++ T+T+ Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA---HSWSTPS-PDTLPTITLPAST 485 Query: 384 ---ESSVTVKIENKESR 397 ESS+ +++ N R Sbjct: 486 VGSESSLALRLVNGGDR 502 Score = 236 bits (602), Expect = 5e-62 Identities = 162/453 (35%), Positives = 203/453 (44%), Gaps = 83/453 (18%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 386 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A + A GN + + Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 431 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157 CSG E L + H C+ A V C+ Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQ-HSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 490 Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217 + ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F Sbjct: 491 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG 550 Query: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ---------SW-- 265 G GPI D V CSG E+YLW CP H CGH EDAG +CS Q SW Sbjct: 551 QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPS 610 Query: 266 ----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309 RL G DRC+G+VEV +RG W TVCD W ++A V+C+ LGCG Sbjct: 611 SHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 670 Query: 310 TAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRS 365 A P SG + C+G E L +C S+ C A V+CSA++S Sbjct: 671 WATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQS 730 Query: 366 LHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397 P S T ESS+ +++ N R Sbjct: 731 RSTPRPDTWPTSHASTAGSESSLALRLVNGGDR 763 Score = 229 bits (585), Expect = 5e-60 Identities = 152/404 (37%), Positives = 197/404 (48%), Gaps = 55/404 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A +P P D TS A + E L +RL NG C G VEV + SW Sbjct: 722 GVICSAAQSRSTPRP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYQGSWGT 778 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 779 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPHN 837 Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENR-ALRLVDGGGACA 171 ++ N + ++CS ++ R + S RA +E+ ALRLV+GG C Sbjct: 838 GWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS---RASTAGSESTLALRLVNGGDRCR 894 Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231 GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CS Sbjct: 895 GRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCS 954 Query: 232 GAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------- 265 G E+YLW CP H CGH EDAG +CS QS W Sbjct: 955 GHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLA 1014 Query: 266 -RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-S 323 RL G DRC G+VEV +RG W TVCD W ++A V+C+ LGCG A+ P S Sbjct: 1015 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1074 Query: 324 GRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364 G + C+G E L +C + ++ C A V+CSA++ Sbjct: 1075 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1118 Score = 228 bits (580), Expect = 2e-59 Identities = 155/422 (36%), Positives = 188/422 (44%), Gaps = 86/422 (20%) Query: 43 LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102 L +RL NG C G VEV SW C WD+ A VCR LGCG A +A Sbjct: 232 LALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP------- 284 Query: 103 ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHACRSDGRRARVTCA- 156 GN + + CSG E L + H C A V C+ Sbjct: 285 --------GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNC-GHSEDAGVICSA 335 Query: 157 -----------------------ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLE 193 + ALRLV+GG C GRVE+L G WG+VCDD+WD Sbjct: 336 PQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395 Query: 194 DAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHK 252 DA+VVCRQLGCGWA A F G GPI D V CSG E+YLW CP H C H Sbjct: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455 Query: 253 EDAGAVCSEHQSW--------------------------RLTGGADRCEGQVEVHFRGVW 286 EDAG +CS SW RL G DRC+G+VEV +RG W Sbjct: 456 EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSW 515 Query: 287 NTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSW 342 TVCD W ++A V+C+ LGCG A+ P SG + C+G E L +C Sbjct: 516 GTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPH 575 Query: 343 RFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPAS------VQTVT-IESSVTVKIENKE 395 S+ C S A V+CSA L L TP P S +QT ESS+ +++ N Sbjct: 576 NGWLSHNCGHSEDAGVICSA---LQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGG 632 Query: 396 SR 397 R Sbjct: 633 DR 634 Score = 180 bits (456), Expect = 4e-45 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV + SW Sbjct: 851 GVICSASQSRPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 907 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 908 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 966 Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172 ++ N ++CS A+ + + ++ V + ALRLV+GG C G Sbjct: 967 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1026 Query: 173 RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232 RVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D V CSG Sbjct: 1027 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1086 Query: 233 AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291 E+YLW CP H CGH EDAG +CS Q N+ Sbjct: 1087 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1124 Query: 292 SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342 W+P+ S CG + G S S YY N + C W Sbjct: 1125 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1169 Score = 117 bits (292), Expect = 4e-26 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Query: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 R + L G CAGRVE+ G WG+VCDD+W +++A VVCRQLGCG AV AL +F Sbjct: 1259 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1318 Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260 G GPI D V CSG E+ LW C H C H+EDAG +CS Sbjct: 1319 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361 Score = 66.6 bits (161), Expect = 7e-11 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%) Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328 C G+VE++ G W TVCD W EA+V+C+ LGCG AV S G Y+ Sbjct: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1321 Query: 329 -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372 C+G E TL C R S+ C+ A V+CS ++LSTP Sbjct: 1322 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1368 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 45 VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94 +RL N +SS C+G VE+ +W C W + AE VCR LGCG A +A Sbjct: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1310 >gi|148539840 deleted in malignant brain tumors 1 isoform a precursor [Homo sapiens] Length = 1785 Score = 244 bits (622), Expect = 2e-64 Identities = 164/450 (36%), Positives = 205/450 (45%), Gaps = 80/450 (17%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + P L +RL NG C G VEV SW Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 386 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 431 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157 CSG E L + H C+ A V C+ Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 490 Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217 + ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F Sbjct: 491 SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 550 Query: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W--- 265 G GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 551 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 610 Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312 RL G DRC+G+VEV +RG W TVCD W ++A V+C+ LGCG A+ Sbjct: 611 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 670 Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368 P SG + C+G E L +C S+ C A V+CSAS+S Sbjct: 671 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 730 Query: 369 LSTPEVPAS-VQTVTIESSVTVKIENKESR 397 S P S T ESS+ +++ N R Sbjct: 731 PSPDTWPTSHASTAGSESSLALRLVNGGDR 760 Score = 238 bits (608), Expect = 1e-62 Identities = 161/437 (36%), Positives = 201/437 (45%), Gaps = 89/437 (20%) Query: 30 SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88 S+ ES + E + L +RL NG C G VE+ SW C WD+ A VCR LGC Sbjct: 86 STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145 Query: 89 GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143 G A + A GN + + CSG E L + H Sbjct: 146 GWAMS---------------APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190 Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176 C G A V C+ + ALRLV+GG C GRVE+ Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249 Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236 L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CSG E+Y Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309 Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271 LW CP H CGH EDAG +CS QS W RL G Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 369 Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329 DRC+G+VEV +RG W TVCD W S+A V+C+ LGCG A P SG + Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429 Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTI---- 383 C+G E L +C S+ C S A V+CSA+ H+ STP P ++ T+T+ Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA---HSWSTPS-PDTLPTITLPAST 485 Query: 384 ---ESSVTVKIENKESR 397 ESS+ +++ N R Sbjct: 486 VGSESSLALRLVNGGDR 502 Score = 235 bits (599), Expect = 1e-61 Identities = 163/452 (36%), Positives = 204/452 (45%), Gaps = 84/452 (18%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 590 GVICSASQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 646 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 647 VCDDYWDTNDANVVCRQLGCGWAMSAP---------------GNARFGQGSGPIVLDDVR 691 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 692 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 750 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA A F G Sbjct: 751 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 810 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 811 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 870 Query: 266 -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314 RL G DRC G+VEV ++G W TVCD W ++A V+C+ LGCG A+ Sbjct: 871 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 930 Query: 315 PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL---- 366 P SG + C+G E L +C S+ C A V+CSA++S Sbjct: 931 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 990 Query: 367 -HNLSTPEVPASVQTVTIESSVTVKIENKESR 397 T +PA TV ESS+ +++ N R Sbjct: 991 PDTWLTTNLPA--LTVGSESSLALRLVNGGDR 1020 Score = 232 bits (591), Expect = 1e-60 Identities = 152/416 (36%), Positives = 190/416 (45%), Gaps = 79/416 (18%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 719 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 775 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A +A GN + + Sbjct: 776 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 820 Query: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159 CSG E L + H C A V C+ ++ Sbjct: 821 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTL 879 Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G Sbjct: 880 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 939 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 940 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 999 Query: 266 -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312 RL G DRC G+VEV +RG W TVCD W ++A V+C+ LGCG A+ Sbjct: 1000 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1059 Query: 313 ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364 P SG + C+G E L +C + ++ C A V+CSA++ Sbjct: 1060 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1115 Score = 200 bits (508), Expect = 4e-51 Identities = 133/344 (38%), Positives = 164/344 (47%), Gaps = 44/344 (12%) Query: 95 SQLAPPTPELPPPPAAGNT----SVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR 150 + L P L P A G+ S + G+P L S E V E + Sbjct: 31 ASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLE---STVAEGSLIPSEST 87 Query: 151 ARVTCAENR----ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206 T AE ALRLV+G G C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGW Sbjct: 88 LESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGW 147 Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ-- 263 A+ A F G GPI D V CSG E+YLW CP H CGH EDAG +CS Q Sbjct: 148 AMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQ 207 Query: 264 ------SW-------------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298 SW RL G DRC G+VEV +RG W TVCD W ++ Sbjct: 208 STLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTND 267 Query: 299 AKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSL 354 A V+C+ LGCG A+ P SG + C+G E L +C ++ C S Sbjct: 268 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSE 327 Query: 355 AARVLCSASRSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397 A V+CSA +S S P S T ESS+ +++ N R Sbjct: 328 DAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR 371 Score = 180 bits (456), Expect = 4e-45 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV + SW Sbjct: 848 GVICSASQSQPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 904 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 905 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 963 Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172 ++ N ++CS A+ + + ++ V + ALRLV+GG C G Sbjct: 964 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1023 Query: 173 RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232 RVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D V CSG Sbjct: 1024 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1083 Query: 233 AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291 E+YLW CP H CGH EDAG +CS Q N+ Sbjct: 1084 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1121 Query: 292 SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342 W+P+ S CG + G S S YY N + C W Sbjct: 1122 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1166 Score = 117 bits (292), Expect = 4e-26 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Query: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 R + L G CAGRVE+ G WG+VCDD+W +++A VVCRQLGCG AV AL +F Sbjct: 1256 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1315 Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260 G GPI D V CSG E+ LW C H C H+EDAG +CS Sbjct: 1316 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1358 Score = 66.6 bits (161), Expect = 7e-11 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%) Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328 C G+VE++ G W TVCD W EA+V+C+ LGCG AV S G Y+ Sbjct: 1267 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1318 Query: 329 -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372 C+G E TL C R S+ C+ A V+CS ++LSTP Sbjct: 1319 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1365 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 45 VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94 +RL N +SS C+G VE+ +W C W + AE VCR LGCG A +A Sbjct: 1255 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1307 >gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] Length = 1662 Score = 241 bits (615), Expect = 2e-63 Identities = 165/455 (36%), Positives = 207/455 (45%), Gaps = 84/455 (18%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV SW Sbjct: 330 GVICSAPQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 386 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128 C WD+ A VCR LGCG A + A GN + + Sbjct: 387 VCDDSWDTSDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 431 Query: 129 CSGAEWRLCEV-----VEHACR------------------SDGRRAR------------- 152 CSG E L + H C+ S G R R Sbjct: 432 CSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPAST 491 Query: 153 VTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212 V + ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A Sbjct: 492 VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPG 551 Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS------- 264 F G GPI D V CSG E+YLW CP H CGH EDAG +CS QS Sbjct: 552 NARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPD 611 Query: 265 -W----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLG 307 W RL G DRC+G+VEV ++G W TVCD W ++A V+C+ LG Sbjct: 612 TWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLG 671 Query: 308 CGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSAS 363 CG A+ P SG + C+G E L +C S+ C S A V+CSAS Sbjct: 672 CGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 731 Query: 364 RSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397 +S S P S T ES++ +++ N R Sbjct: 732 QSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR 766 Score = 235 bits (600), Expect = 9e-62 Identities = 159/439 (36%), Positives = 195/439 (44%), Gaps = 87/439 (19%) Query: 30 SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88 S+ ES + E + L +RL NG C G VE+ SW C WD+ A VCR LGC Sbjct: 86 STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145 Query: 89 GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143 G A +A GN + + CSG E L + H Sbjct: 146 GWAMSAP---------------GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190 Query: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176 C G A V C+ + ALRLV+GG C GRVE+ Sbjct: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249 Query: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236 L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CSG E+Y Sbjct: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309 Query: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271 LW CP H CGH EDAG +CS QS W RL G Sbjct: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGG 369 Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329 DRC+G+VEV +RG W TVCD W S+A V+C+ LGCG A P SG + Sbjct: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429 Query: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS---------TPEVPASV 378 C+G E L +C S+ C S A V+CSA+ S S P + Sbjct: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPA 489 Query: 379 QTVTIESSVTVKIENKESR 397 TV ESS+ +++ N R Sbjct: 490 STVGSESSLALRLVNGGDR 508 Score = 235 bits (599), Expect = 1e-61 Identities = 161/447 (36%), Positives = 207/447 (46%), Gaps = 66/447 (14%) Query: 9 GLLTAALSGHPSPAP-----PDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLE 63 G++ +A +P+P D L T + + L +RL NG C G VEV Sbjct: 459 GVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYR 518 Query: 64 ASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPE---------LPPPPAAGNTS 114 SW C WD+ A VCR LGCG A LAP L +GN S Sbjct: 519 GSWGTVCDDSWDTNDANVVCRQLGCGWA----MLAPGNARFGQGSGPIVLDDVRCSGNES 574 Query: 115 ----------VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLV 164 ++ N + ++CS A+ R + S A + ALRLV Sbjct: 575 YLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAG--SESSLALRLV 632 Query: 165 DGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIH 224 +GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI Sbjct: 633 NGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 692 Query: 225 RDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W---------- 265 D V CSG E+YLW CP H CGH EDAG +CS QS W Sbjct: 693 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGS 752 Query: 266 ------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLP 319 RL G DRC G+VEV ++G W TVCD W ++A V+C+ LGCG A+ P Sbjct: 753 ESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQ 812 Query: 320 HSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLS 370 SG + C+G E L +C S+ C A V+CSA++S Sbjct: 813 FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWL 872 Query: 371 TPEVPASVQTVTIESSVTVKIENKESR 397 T +PA TV ESS+ +++ N R Sbjct: 873 TTNLPA--LTVGSESSLALRLVNGGDR 897 Score = 229 bits (585), Expect = 5e-60 Identities = 152/404 (37%), Positives = 197/404 (48%), Gaps = 55/404 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A +P P D TS A + E L +RL NG C G VEV + SW Sbjct: 596 GVICSAAQSRSTPRP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYQGSWGT 652 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 653 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV-LDDVRCSGHESYLWSCPHN 711 Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENR-ALRLVDGGGACA 171 ++ N + ++CS ++ R + S RA +E+ ALRLV+GG C Sbjct: 712 GWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS---RASTAGSESTLALRLVNGGDRCR 768 Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231 GRVE+L G WG+VCDD WD DA+VVCRQLGCGWA+ A F G GPI D V CS Sbjct: 769 GRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCS 828 Query: 232 GAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------- 265 G E+YLW CP H CGH EDAG +CS QS W Sbjct: 829 GHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLA 888 Query: 266 -RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-S 323 RL G DRC G+VEV +RG W TVCD W ++A V+C+ LGCG A+ P S Sbjct: 889 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 948 Query: 324 GRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364 G + C+G E L +C + ++ C A V+CSA++ Sbjct: 949 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 992 Score = 180 bits (456), Expect = 4e-45 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%) Query: 9 GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68 G++ +A P+P+P D TS A + E L +RL NG C G VEV + SW Sbjct: 725 GVICSASQSRPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 781 Query: 69 ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114 C WD+ A VCR LGCG A +A Q + P L +G+ S Sbjct: 782 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 840 Query: 115 --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172 ++ N ++CS A+ + + ++ V + ALRLV+GG C G Sbjct: 841 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 900 Query: 173 RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232 RVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G GPI D V CSG Sbjct: 901 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 960 Query: 233 AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291 E+YLW CP H CGH EDAG +CS Q N+ Sbjct: 961 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 998 Query: 292 SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342 W+P+ S CG + G S S YY N + C W Sbjct: 999 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1043 Score = 117 bits (292), Expect = 4e-26 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%) Query: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 R + L G CAGRVE+ G WG+VCDD+W +++A VVCRQLGCG AV AL +F Sbjct: 1133 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1192 Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260 G GPI D V CSG E+ LW C H C H+EDAG +CS Sbjct: 1193 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235 Score = 66.6 bits (161), Expect = 7e-11 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%) Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328 C G+VE++ G W TVCD W EA+V+C+ LGCG AV S G Y+ Sbjct: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1195 Query: 329 -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372 C+G E TL C R S+ C+ A V+CS ++LSTP Sbjct: 1196 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1242 Score = 44.7 bits (104), Expect = 3e-04 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 45 VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94 +RL N +SS C+G VE+ +W C W + AE VCR LGCG A +A Sbjct: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1184 >gi|44889963 CD163 antigen isoform b [Homo sapiens] Length = 1121 Score = 201 bits (512), Expect = 1e-51 Identities = 122/358 (34%), Positives = 174/358 (48%), Gaps = 24/358 (6%) Query: 40 GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99 G L +RL G S C+GTVEV ++ C W + A+ VCR LGCG A S Sbjct: 368 GSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSY--- 424 Query: 100 PTPELPPPPAAGNTSVAANATLAGAPALL-CSGAEWR--LCEVVEHACRSDGRRARVTCA 156 ++ A NT + ++ +L C +W C+ E A ++TC+ Sbjct: 425 ---QVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEA--------KITCS 473 Query: 157 ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216 +R RLV G C+GRVE+ WGS+CD + LE A V+CR+L CG V L G HF Sbjct: 474 AHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHF 533 Query: 217 TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGADRCE 275 G G I ++ C G E++L CP P + C H D G VCS + RL G CE Sbjct: 534 GEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCE 593 Query: 276 GQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSG----RMYYSCN 331 G+VE+ G W ++C+S W +A VLCQ L CG A+ P G R + C Sbjct: 594 GRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCT 653 Query: 332 GEELTLSNCSWRFNNSNLCSQSLAARVLCSA--SRSLHNLSTPEVPASVQTVTIESSV 387 G E + +C ++LC A V+CS S++L + ++ + + T+ ES+V Sbjct: 654 GTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAV 711 Score = 200 bits (509), Expect = 3e-51 Identities = 114/308 (37%), Positives = 157/308 (50%), Gaps = 32/308 (10%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGA---EAASQLAPPT 101 +RL NG + C G VE++ +W C + WD A +C+ L CG A ++ Sbjct: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642 Query: 102 PEL---------------PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRS 146 ++ P A S+ + +A +++CSG + + + Sbjct: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVA---SVICSGNQSQTLSSCNSSSLG 699 Query: 147 DGR-----RARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQ 201 R + V C E+ LRLV+GGG CAGRVE+ G WG++CDD+WDL DAHVVCRQ Sbjct: 700 PTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQ 759 Query: 202 LGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260 LGCG A+ A HF G GPI D++ C+G E+ +W C GQ C HKEDAG +CS Sbjct: 760 LGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819 Query: 261 EHQSWRLTGGADR--CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGL 318 E S RLT A R C G++EV + G W TV S + V+C+ LGC ++ K Sbjct: 820 EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGC---ADKGKIN 876 Query: 319 PHSLSGRM 326 P SL M Sbjct: 877 PASLDKAM 884 Score = 198 bits (503), Expect = 2e-50 Identities = 119/340 (35%), Positives = 170/340 (50%), Gaps = 32/340 (9%) Query: 40 GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99 G L +RLT G + CSG +E++ + W C ++ A +CR L CG A + S Sbjct: 154 GSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFS---- 209 Query: 100 PTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVV-----EHACRSDGRRARVT 154 G+++ + L+C+G E L +H C A V Sbjct: 210 -----------GSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNC-DHAEDAGVI 257 Query: 155 CAENR--ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212 C++ +LRLVDG C+GR+E+ GEWG++CDD WD DA V C+QLGC AV A+ Sbjct: 258 CSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317 Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQ--SWRLTG 269 ++ + G G I D V+C G E +W C G+HYC H EDAG CS+ RL G Sbjct: 318 RVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRG 377 Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY- 328 G RC G VEV + + VCD W EA V+C+ LGCG+A++ + + + Sbjct: 378 GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437 Query: 329 ---SCNGEELTLSNC-SWRFNNSNLCSQSLAARVLCSASR 364 SCNG E +L +C +W++ C A++ CSA R Sbjct: 438 FLSSCNGNETSLWDCKNWQWGGLT-CDHYEEAKITCSAHR 476 Score = 194 bits (493), Expect = 2e-49 Identities = 119/343 (34%), Positives = 163/343 (47%), Gaps = 43/343 (12%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 +RL +G + CSG VEV+++ W C W A +C LGC P Sbjct: 51 LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGC-------------PTA 97 Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG----------RRARVT 154 P N+S A + + C G E L + C+ DG + A VT Sbjct: 98 IKAPGWANSS--AGSGRIWMDHVSCRGNESALWD-----CKHDGWGKHSNCTHQQDAGVT 150 Query: 155 CAE--NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212 C++ N +RL GG C+GR+E+ G WG+VCDD ++++ A V+CRQL CG AV Sbjct: 151 CSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSG 210 Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSE--HQSWRLTG 269 +F G GPI D + C+G E+ LW+C G+H C H EDAG +CS+ S RL Sbjct: 211 SSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVD 270 Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTA------VERPKGLPHSLS 323 G C G++EV F+G W T+CD W +A V C+ LGC TA V KG H Sbjct: 271 GVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWL 330 Query: 324 GRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366 + SC G E + C + C+ + A V CS L Sbjct: 331 DSV--SCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDL 371 Score = 171 bits (432), Expect = 3e-42 Identities = 116/371 (31%), Positives = 157/371 (42%), Gaps = 69/371 (18%) Query: 46 RLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELP 105 RL G CSG VEV+ +W C + + AA +CR L CG + Sbjct: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSI----------- 527 Query: 106 PPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVV---EHACRSDGRRARVTCAENRA 160 G A C G E L C V E C S R V C+ Sbjct: 528 ----LGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTC-SHSRDVGVVCSRYTE 582 Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220 +RLV+G C GRVE+ G WGS+C+ WD+EDAHV+C+QL CG A+ G F G Sbjct: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642 Query: 221 GPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQS--------------- 264 G I R +C+G E ++ DCP G C ++ A +CS +QS Sbjct: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR 702 Query: 265 ----------------WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC 308 RL G RC G+VE++ G W T+CD W S+A V+C+ LGC Sbjct: 703 PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762 Query: 309 GTAVERPKGLPHSLSGR-----MYYSCNGEELTL----------SNCSWRFNNSNLCSQS 353 G A+ G H G CNG+E + NC + + +CS+ Sbjct: 763 GEAI-NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEF 821 Query: 354 LAARVLCSASR 364 ++ R+ ASR Sbjct: 822 MSLRLTSEASR 832 Score = 154 bits (390), Expect = 2e-37 Identities = 83/217 (38%), Positives = 118/217 (54%), Gaps = 8/217 (3%) Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217 ++ LRLVDG C+GRVE+ EWG+VC++ W +E V+C QLGC A++A + + Sbjct: 48 DKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSS 107 Query: 218 PGRGPIHRDQVNCSGAEAYLWDC--PGLPGQHYCGHKEDAGAVCSE--HQSWRLTGGADR 273 G G I D V+C G E+ LWDC G C H++DAG CS+ + RLT G + Sbjct: 108 AGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNM 167 Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS--- 329 C G++E+ F+G W TVCD + A V+C+ L CG+AV SG +++ Sbjct: 168 CSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLI 227 Query: 330 CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366 CNG E L NC + + C + A V+CS L Sbjct: 228 CNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADL 264 Score = 150 bits (380), Expect = 3e-36 Identities = 118/408 (28%), Positives = 169/408 (41%), Gaps = 47/408 (11%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 +RL NG C+G VE+ E SW C WD A VCR LGCG EA + Sbjct: 719 LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCG--EAIN--------- 767 Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR----ARVTCAENRA 160 A G+ + C+G E R+ + H R A V C+E + Sbjct: 768 ----ATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS 823 Query: 161 LRLVDGGG--ACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 LRL ACAGR+E+ +G WG+V + VVCRQLGC + P Sbjct: 824 LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKA 883 Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPGQ-HYCGHKEDAGAVCSEHQSWRLTGGADRCEGQ 277 P+ D V C LW CP P + E+ C RL G C G+ Sbjct: 884 MSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCD--NKIRLQEGPTSCSGR 941 Query: 278 VEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGE 333 VE+ G W TVCD W +A+V+CQ LGCG A++ K +G ++ + C G Sbjct: 942 VEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGN 1001 Query: 334 ELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVTVKIEN 393 E +L +C R + C A V C+ ++S + P T Sbjct: 1002 ESSLWDCPARRWGHSECGHKEDAAVNCT------DISVQKTPQKATT------------G 1043 Query: 394 KESRELMLLIPSIVLGILLLGSLIFIAFILLRIKGKYALPVMVNHQHL 441 + SR+ + I LG++LL + + F+ + + + L V ++L Sbjct: 1044 RSSRQSSFIAVGI-LGVVLLAIFVALFFLTKKRRQRQRLAVSSRGENL 1090 Score = 135 bits (339), Expect = 2e-31 Identities = 99/313 (31%), Positives = 146/313 (46%), Gaps = 30/313 (9%) Query: 41 ERLPVRLTNGSS--SCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98 E + +RLT+ +S +C+G +EV +W + VCR LGC ++ Sbjct: 820 EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADK---GKIN 876 Query: 99 PPTPELPPPPAAGNTSVAANATLAGAPALL--CSGAEWRLCEVVEHACRSDGRRARVTCA 156 P + + A N P L C + W E S +TC Sbjct: 877 PASLD----KAMSIPMWVDNVQCPKGPDTLWQCPSSPW------EKRLASPSEETWITC- 925 Query: 157 ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216 + +RL +G +C+GRVE+ G WG+VCDD+WDL+DA VVC+QLGCG A++A F Sbjct: 926 -DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEF 984 Query: 217 TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWR-----LTGG 270 G GPI ++V C G E+ LWDCP G CGHKEDA C++ + TG Sbjct: 985 GQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGR 1044 Query: 271 ADRCEGQVEVHFRG-VWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYS 329 + R + V G V + + ++ ++ + Q L + R + L H + R S Sbjct: 1045 SSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQRLAVSS---RGENLVHQIQYREMNS 1101 Query: 330 C-NGEELTLSNCS 341 C N ++L L N S Sbjct: 1102 CLNADDLDLMNSS 1114 >gi|44662834 CD163 antigen isoform a [Homo sapiens] Length = 1156 Score = 201 bits (512), Expect = 1e-51 Identities = 122/358 (34%), Positives = 174/358 (48%), Gaps = 24/358 (6%) Query: 40 GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99 G L +RL G S C+GTVEV ++ C W + A+ VCR LGCG A S Sbjct: 368 GSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSY--- 424 Query: 100 PTPELPPPPAAGNTSVAANATLAGAPALL-CSGAEWR--LCEVVEHACRSDGRRARVTCA 156 ++ A NT + ++ +L C +W C+ E A ++TC+ Sbjct: 425 ---QVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEA--------KITCS 473 Query: 157 ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216 +R RLV G C+GRVE+ WGS+CD + LE A V+CR+L CG V L G HF Sbjct: 474 AHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHF 533 Query: 217 TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGADRCE 275 G G I ++ C G E++L CP P + C H D G VCS + RL G CE Sbjct: 534 GEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCE 593 Query: 276 GQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSG----RMYYSCN 331 G+VE+ G W ++C+S W +A VLCQ L CG A+ P G R + C Sbjct: 594 GRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCT 653 Query: 332 GEELTLSNCSWRFNNSNLCSQSLAARVLCSA--SRSLHNLSTPEVPASVQTVTIESSV 387 G E + +C ++LC A V+CS S++L + ++ + + T+ ES+V Sbjct: 654 GTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAV 711 Score = 200 bits (509), Expect = 3e-51 Identities = 114/308 (37%), Positives = 157/308 (50%), Gaps = 32/308 (10%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGA---EAASQLAPPT 101 +RL NG + C G VE++ +W C + WD A +C+ L CG A ++ Sbjct: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642 Query: 102 PEL---------------PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRS 146 ++ P A S+ + +A +++CSG + + + Sbjct: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVA---SVICSGNQSQTLSSCNSSSLG 699 Query: 147 DGR-----RARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQ 201 R + V C E+ LRLV+GGG CAGRVE+ G WG++CDD+WDL DAHVVCRQ Sbjct: 700 PTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQ 759 Query: 202 LGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260 LGCG A+ A HF G GPI D++ C+G E+ +W C GQ C HKEDAG +CS Sbjct: 760 LGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819 Query: 261 EHQSWRLTGGADR--CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGL 318 E S RLT A R C G++EV + G W TV S + V+C+ LGC ++ K Sbjct: 820 EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGC---ADKGKIN 876 Query: 319 PHSLSGRM 326 P SL M Sbjct: 877 PASLDKAM 884 Score = 198 bits (503), Expect = 2e-50 Identities = 119/340 (35%), Positives = 170/340 (50%), Gaps = 32/340 (9%) Query: 40 GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99 G L +RLT G + CSG +E++ + W C ++ A +CR L CG A + S Sbjct: 154 GSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFS---- 209 Query: 100 PTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVV-----EHACRSDGRRARVT 154 G+++ + L+C+G E L +H C A V Sbjct: 210 -----------GSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNC-DHAEDAGVI 257 Query: 155 CAENR--ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212 C++ +LRLVDG C+GR+E+ GEWG++CDD WD DA V C+QLGC AV A+ Sbjct: 258 CSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317 Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQ--SWRLTG 269 ++ + G G I D V+C G E +W C G+HYC H EDAG CS+ RL G Sbjct: 318 RVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRG 377 Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY- 328 G RC G VEV + + VCD W EA V+C+ LGCG+A++ + + + Sbjct: 378 GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437 Query: 329 ---SCNGEELTLSNC-SWRFNNSNLCSQSLAARVLCSASR 364 SCNG E +L +C +W++ C A++ CSA R Sbjct: 438 FLSSCNGNETSLWDCKNWQWGGLT-CDHYEEAKITCSAHR 476 Score = 194 bits (493), Expect = 2e-49 Identities = 119/343 (34%), Positives = 163/343 (47%), Gaps = 43/343 (12%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 +RL +G + CSG VEV+++ W C W A +C LGC P Sbjct: 51 LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGC-------------PTA 97 Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG----------RRARVT 154 P N+S A + + C G E L + C+ DG + A VT Sbjct: 98 IKAPGWANSS--AGSGRIWMDHVSCRGNESALWD-----CKHDGWGKHSNCTHQQDAGVT 150 Query: 155 CAE--NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212 C++ N +RL GG C+GR+E+ G WG+VCDD ++++ A V+CRQL CG AV Sbjct: 151 CSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSG 210 Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSE--HQSWRLTG 269 +F G GPI D + C+G E+ LW+C G+H C H EDAG +CS+ S RL Sbjct: 211 SSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVD 270 Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTA------VERPKGLPHSLS 323 G C G++EV F+G W T+CD W +A V C+ LGC TA V KG H Sbjct: 271 GVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWL 330 Query: 324 GRMYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366 + SC G E + C + C+ + A V CS L Sbjct: 331 DSV--SCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDL 371 Score = 171 bits (432), Expect = 3e-42 Identities = 116/371 (31%), Positives = 157/371 (42%), Gaps = 69/371 (18%) Query: 46 RLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELP 105 RL G CSG VEV+ +W C + + AA +CR L CG + Sbjct: 479 RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSI----------- 527 Query: 106 PPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVV---EHACRSDGRRARVTCAENRA 160 G A C G E L C V E C S R V C+ Sbjct: 528 ----LGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTC-SHSRDVGVVCSRYTE 582 Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220 +RLV+G C GRVE+ G WGS+C+ WD+EDAHV+C+QL CG A+ G F G Sbjct: 583 IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGN 642 Query: 221 GPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQS--------------- 264 G I R +C+G E ++ DCP G C ++ A +CS +QS Sbjct: 643 GQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR 702 Query: 265 ----------------WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC 308 RL G RC G+VE++ G W T+CD W S+A V+C+ LGC Sbjct: 703 PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762 Query: 309 GTAVERPKGLPHSLSGR-----MYYSCNGEELTL----------SNCSWRFNNSNLCSQS 353 G A+ G H G CNG+E + NC + + +CS+ Sbjct: 763 GEAI-NATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEF 821 Query: 354 LAARVLCSASR 364 ++ R+ ASR Sbjct: 822 MSLRLTSEASR 832 Score = 154 bits (390), Expect = 2e-37 Identities = 83/217 (38%), Positives = 118/217 (54%), Gaps = 8/217 (3%) Query: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217 ++ LRLVDG C+GRVE+ EWG+VC++ W +E V+C QLGC A++A + + Sbjct: 48 DKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSS 107 Query: 218 PGRGPIHRDQVNCSGAEAYLWDC--PGLPGQHYCGHKEDAGAVCSE--HQSWRLTGGADR 273 G G I D V+C G E+ LWDC G C H++DAG CS+ + RLT G + Sbjct: 108 AGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNM 167 Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS--- 329 C G++E+ F+G W TVCD + A V+C+ L CG+AV SG +++ Sbjct: 168 CSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLI 227 Query: 330 CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366 CNG E L NC + + C + A V+CS L Sbjct: 228 CNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADL 264 Score = 150 bits (380), Expect = 3e-36 Identities = 118/408 (28%), Positives = 169/408 (41%), Gaps = 47/408 (11%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 +RL NG C+G VE+ E SW C WD A VCR LGCG EA + Sbjct: 719 LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCG--EAIN--------- 767 Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR----ARVTCAENRA 160 A G+ + C+G E R+ + H R A V C+E + Sbjct: 768 ----ATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS 823 Query: 161 LRLVDGGG--ACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 LRL ACAGR+E+ +G WG+V + VVCRQLGC + P Sbjct: 824 LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKA 883 Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPGQ-HYCGHKEDAGAVCSEHQSWRLTGGADRCEGQ 277 P+ D V C LW CP P + E+ C RL G C G+ Sbjct: 884 MSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCD--NKIRLQEGPTSCSGR 941 Query: 278 VEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGE 333 VE+ G W TVCD W +A+V+CQ LGCG A++ K +G ++ + C G Sbjct: 942 VEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGN 1001 Query: 334 ELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVTVKIEN 393 E +L +C R + C A V C+ ++S + P T Sbjct: 1002 ESSLWDCPARRWGHSECGHKEDAAVNCT------DISVQKTPQKATT------------G 1043 Query: 394 KESRELMLLIPSIVLGILLLGSLIFIAFILLRIKGKYALPVMVNHQHL 441 + SR+ + I LG++LL + + F+ + + + L V ++L Sbjct: 1044 RSSRQSSFIAVGI-LGVVLLAIFVALFFLTKKRRQRQRLAVSSRGENL 1090 Score = 135 bits (341), Expect = 9e-32 Identities = 107/338 (31%), Positives = 157/338 (46%), Gaps = 34/338 (10%) Query: 41 ERLPVRLTNGSS--SCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98 E + +RLT+ +S +C+G +EV +W + VCR LGC ++ Sbjct: 820 EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADK---GKIN 876 Query: 99 PPTPELPPPPAAGNTSVAANATLAGAPALL--CSGAEWRLCEVVEHACRSDGRRARVTCA 156 P + + A N P L C + W E S +TC Sbjct: 877 PASLD----KAMSIPMWVDNVQCPKGPDTLWQCPSSPW------EKRLASPSEETWITC- 925 Query: 157 ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF 216 + +RL +G +C+GRVE+ G WG+VCDD+WDL+DA VVC+QLGCG A++A F Sbjct: 926 -DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEF 984 Query: 217 TPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWR-----LTGG 270 G GPI ++V C G E+ LWDCP G CGHKEDA C++ + TG Sbjct: 985 GQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGR 1044 Query: 271 ADRCEGQVEVHFRG-VWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYS 329 + R + V G V + + ++ ++ + Q L + R + L H + R S Sbjct: 1045 SSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQRLAVSS---RGENLVHQIQYREMNS 1101 Query: 330 C-NGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366 C N ++L L N S NS+ S +A L S S+ L Sbjct: 1102 CLNADDLDLMNSS---ENSHE-SADFSAAELISVSKFL 1135 >gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo sapiens] Length = 1453 Score = 199 bits (506), Expect = 7e-51 Identities = 111/288 (38%), Positives = 153/288 (53%), Gaps = 23/288 (7%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAAS---QLAPPT 101 VRL NG S C G VE+ + W C WD A +CR L CG A + + + + Sbjct: 900 VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERS 959 Query: 102 PELPPPP--AAGNTSVAANA--TLAGAP--------ALLCSGAEWR-----LCEVVEHAC 144 + GN S+ N T+ GAP +++C+G+ + L V + Sbjct: 960 VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYL 1019 Query: 145 RSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGC 204 + + + C E++ LRLVDG CAGRVE+ G WG++CDD WDL DAHVVC++LGC Sbjct: 1020 SAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGC 1079 Query: 205 GWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQ 263 G A A HF G GPI D +NC+G E++LW CP GQH C HKEDAG +CSE Sbjct: 1080 GVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFT 1139 Query: 264 SWRLTG--GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309 + RL + C G++EV + G W +V + A ++C+ LGCG Sbjct: 1140 ALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCG 1187 Score = 197 bits (502), Expect = 2e-50 Identities = 123/343 (35%), Positives = 172/343 (50%), Gaps = 32/343 (9%) Query: 34 SELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEA 93 S + G L +RL +GS++CSG VEVR+ W C W + A VC+ LGC + Sbjct: 358 SVICSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVF 417 Query: 94 ASQLAPPTPE-----LPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG 148 S+ A P+ E + GN S + T G C RSD Sbjct: 418 GSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFR-------------RSD- 463 Query: 149 RRARVTCAENRAL--RLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206 A V C++ L RLV C GR+E+ GEWG+VC D W +A VVC+QLGCG Sbjct: 464 --AGVICSDKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGK 521 Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSW 265 + +F GPI D V+C G E+ +WDC G+H C H+ED CS +W Sbjct: 522 PMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATW 581 Query: 266 --RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLS 323 RL GG++RC G++EV+F+G W TVCD W A V+C L C +++ GL ++ + Sbjct: 582 GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSI-IGMGLGNAST 640 Query: 324 --GRMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361 G+++ SC+G+E L +C +N CS S V+CS Sbjct: 641 GYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683 Score = 184 bits (468), Expect = 2e-46 Identities = 121/342 (35%), Positives = 155/342 (45%), Gaps = 32/342 (9%) Query: 40 GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99 G L +RL NG CSGTVEV+ + W C W++ A+ VC+ LGC + A + Sbjct: 43 GTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQ 102 Query: 100 PTPE-----LPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVT 154 L GN S C EW H C G V Sbjct: 103 AVTRHGKIWLDDVSCYGNESALWE----------CQHREWG-----SHNCYH-GEDVGVN 146 Query: 155 C--AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212 C N LRLVDG +C+GRVE+ WG++CDD W+L A VVCRQLGC + + Sbjct: 147 CYGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSG 206 Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVC--SEHQSWRLTG 269 ++ PI D + C G E LW+C G H C H ED C S RL G Sbjct: 207 VVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVG 266 Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMY-- 327 G +RC G+VE+ +G W TVC +W + A V+C+ LGCGTA+ GLPH SG Sbjct: 267 GTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHF-AGLPHLQSGSDVVW 325 Query: 328 ---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366 SC+G E L +C + C V+CS L Sbjct: 326 LDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADL 367 Score = 181 bits (460), Expect = 1e-45 Identities = 120/368 (32%), Positives = 173/368 (47%), Gaps = 31/368 (8%) Query: 43 LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102 + +RL GSS C+G VEV ++ + C W AE VCR L CG A S+ Sbjct: 688 MELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSR------ 741 Query: 103 ELPPPPAAGNTS--VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRA 160 P T + +N+ G A L W E + AC + A + C+ +R Sbjct: 742 ---EPHFTERTLHILMSNSGCTGGEASLWDCIRW---EWKQTACHLN-MEASLICSAHRQ 794 Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220 RLV C+GRVE+ W SVCD + L A+V+CR+L CG A+ G HF G Sbjct: 795 PRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGN 854 Query: 221 GPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVE 279 G ++ C G+E +L CP + + C H + G VCS + RL G +C+GQVE Sbjct: 855 GLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVE 914 Query: 280 VHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKG-LPHSLSGRMY---YSCNGEEL 335 ++ G W ++CD+ W P +A+VLC+ L CGTA+ G S R++ + C G E Sbjct: 915 INVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNES 974 Query: 336 TLSNCSWRFNNSNLCSQSLAARVLCSASRS------LHNLSTPEVPASVQTVTIESSVTV 389 L NC + C V+C+ S + L N+S P + A E S + Sbjct: 975 LLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSA-----VPEGSALI 1029 Query: 390 KIENKESR 397 +E+K R Sbjct: 1030 CLEDKRLR 1037 Score = 173 bits (439), Expect = 4e-43 Identities = 111/338 (32%), Positives = 154/338 (45%), Gaps = 30/338 (8%) Query: 43 LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102 L +RL +G++SCSG VEV+ + W C W+ A VCR LGC + +S + Sbjct: 153 LGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPA 212 Query: 103 ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVE-----HACRSDGRRARVTCAE 157 L P +LC G E L H C S +TC + Sbjct: 213 VLRP---------------IWLDDILCQGNELALWNCRHRGWGNHDC-SHNEDVTLTCYD 256 Query: 158 NR--ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH 215 + LRLV G C GRVE+ G WG+VC W+ A VVC+QLGCG A+ H Sbjct: 257 SSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPH 316 Query: 216 FTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHY-CGHKEDAGAVCSE--HQSWRLTGGAD 272 G + D V+CSG E++LWDC ++ C H+ D +CS+ RL G++ Sbjct: 317 LQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLELRLADGSN 376 Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY---- 328 C G+VEV W T+CD W +A V+C+ LGC +V + S R + Sbjct: 377 NCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSI 436 Query: 329 SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366 SC G E L +C++ C + A V+CS L Sbjct: 437 SCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADL 474 Score = 152 bits (384), Expect = 1e-36 Identities = 112/368 (30%), Positives = 153/368 (41%), Gaps = 55/368 (14%) Query: 46 RLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELP 105 RL CSG VEV+ +W C + + AA +CR L CG A + S Sbjct: 796 RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLS---------- 845 Query: 106 PPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVVEHACRS--DGRRARVTCAENRAL 161 G+ N L A C G+E L C +V+H + R V C+ + Sbjct: 846 ----VGDHFGKGNG-LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDV 900 Query: 162 RLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRG 221 RLV+G C G+VE+ G WGS+CD WD EDA V+CRQL CG A+ G + Sbjct: 901 RLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSV 960 Query: 222 PIHRDQVNCSGAEAYLWDCP-GLPGQHYCGH----------------------------- 251 + + +C G E+ L +C + G C H Sbjct: 961 RVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLS 1020 Query: 252 --KEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309 E + +C E + RL G RC G+VE++ G W T+CD W S+A V+CQ LGCG Sbjct: 1021 AVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG 1080 Query: 310 TAVERPKGLPHSL-SGRMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRS 365 A SG ++ +C G E L C R + C A V+CS + Sbjct: 1081 VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTA 1140 Query: 366 LHNLSTPE 373 L S E Sbjct: 1141 LRLYSETE 1148 Score = 152 bits (383), Expect = 1e-36 Identities = 108/333 (32%), Positives = 143/333 (42%), Gaps = 36/333 (10%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 +RL GS+ CSG +EV + W C W+S+AA VC L C + L Sbjct: 583 LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGL------- 635 Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG---------RRARVTC 155 GN S + C G E L +CR+ G V C Sbjct: 636 ------GNASTGYGKIWLDDVS--CDGDESDLW-----SCRNSGWGNNDCSHSEDVGVIC 682 Query: 156 --AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPG 213 A + LRLV G CAG+VE+ G G +C + W + A VVCRQL CG A++ Sbjct: 683 SDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSRE 742 Query: 214 LHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGAD 272 HFT I C+G EA LWDC Q C +A +CS H+ RL G Sbjct: 743 PHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLVGADM 802 Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPK----GLPHSLSGRMYY 328 C G+VEV W +VCDS++ A VLC+ L CG A+ G + L+ + Sbjct: 803 PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKF 862 Query: 329 SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361 C G E L+ C + + C S V+CS Sbjct: 863 QCEGSETHLALCPIVQHPEDTCIHSREVGVVCS 895 Score = 145 bits (366), Expect = 1e-34 Identities = 124/410 (30%), Positives = 178/410 (43%), Gaps = 66/410 (16%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 +RL +G S C+G VE+ + W C WD A VC+ LGCG Sbjct: 1036 LRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG--------------- 1080 Query: 105 PPPPAAGNTSVAANATLAGAPALL----CSGAEWRLCEVV-----EHACRSDGRRARVTC 155 A N +V+A+ P L C+G E L + +H CR A V C Sbjct: 1081 ----VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHK-EDAGVIC 1135 Query: 156 AENRALRLVDGGG--ACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW-AVQALP 212 +E ALRL +CAGR+E+ +G WGSV A +VCRQLGCG V +L Sbjct: 1136 SEFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLA 1195 Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSEHQSWRLTGGAD 272 L T G G + D + C +W C P + + + E + R+ GG Sbjct: 1196 PLSKT-GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRI-RVRGGDT 1253 Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS-- 329 C G+VE+ G W TVCD W +EA+V+CQ LGCG+A+ + +G ++ Sbjct: 1254 ECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDM 1313 Query: 330 -CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVT 388 C G E L +C + + C A V CS + Sbjct: 1314 RCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQ------------------------S 1349 Query: 389 VKIENKESRELMLLIPSIVLGILLLGSLIFIAFIL-LRIKGKYALPVMVN 437 +K N S L L++ SI G+LLL ++FI F+ R++ + LP+ V+ Sbjct: 1350 LKSLNASSGHLALILSSI-FGLLLL--VLFILFLTWCRVQKQKHLPLRVS 1396 >gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] Length = 343 Score = 192 bits (487), Expect = 1e-48 Identities = 106/244 (43%), Positives = 130/244 (53%), Gaps = 30/244 (12%) Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VVCRQLGCGWA+ A F G Sbjct: 17 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 76 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS--------EHQSW----- 265 GPI D V CSG E+YLW CP H CGH EDAG +CS +SW Sbjct: 77 SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFL 136 Query: 266 ------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVE 313 RL G DRC+G+VEV +RG W TVCD W ++A V+C+ LGCG A Sbjct: 137 CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 196 Query: 314 RPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNL 369 P SG + C+G E L +C S+ C A V+CS S ++ Sbjct: 197 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGSWAVAGP 256 Query: 370 STPE 373 P+ Sbjct: 257 RRPQ 260 Score = 173 bits (439), Expect = 4e-43 Identities = 104/252 (41%), Positives = 123/252 (48%), Gaps = 37/252 (14%) Query: 43 LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102 L +RL NG C G VEV SW C WD+ A VCR LGCG A LAP Sbjct: 16 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA----MLAPGNA 71 Query: 103 E---------LPPPPAAGNTS----------VAANATLAGAPALLCSGAEWRLCEVVEHA 143 L +GN S ++ N + ++CSG R Sbjct: 72 RFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRT------P 125 Query: 144 CRSDGRRARVTCA-----ENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVV 198 R +R C+ + ALRLV+GG C GRVE+L G WG+VCDD+WD DA+VV Sbjct: 126 IRPRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 185 Query: 199 CRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGA 257 CRQLGCGWA A F G GPI D V CSG E+YLW CP H CGH EDAG Sbjct: 186 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGV 245 Query: 258 VCSEHQSWRLTG 269 +CS SW + G Sbjct: 246 ICS--GSWAVAG 255 Score = 57.0 bits (136), Expect = 5e-08 Identities = 26/56 (46%), Positives = 29/56 (51%) Query: 39 PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94 P L +RL NG C G VEV SW C WD+ A VCR LGCG A +A Sbjct: 142 PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 197 >gi|5174411 CD5 molecule-like [Homo sapiens] Length = 347 Score = 191 bits (485), Expect = 2e-48 Identities = 123/341 (36%), Positives = 155/341 (45%), Gaps = 42/341 (12%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 VRL G C G VEV + W C WD + +CR LGCG A P+ L Sbjct: 24 VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGT-----PSGIL 78 Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVVEHACRSDGRRARVTCAENRA-- 160 PPA V + + C+G E L CE E S A +C + Sbjct: 79 YEPPAEKEQKVLIQS-------VSCTGTEDTLAQCEQEEVYDCSHDEDAGASCENPESSF 131 Query: 161 ------LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGL 214 +RL DG G C GRVE+ +W +VC W L A VVCRQLGCG AV Sbjct: 132 SPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRC 191 Query: 215 H-FTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGAD 272 + GR PI Q++CSG EA L DCP P G++ C H ED C + RL GG + Sbjct: 192 NKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDN 251 Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYS--- 329 C G++EV +GVW +VCD W E +V+C+ LGCG K L S R Y Sbjct: 252 LCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCG------KSLSPSFRDRKCYGPGV 305 Query: 330 ---------CNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361 C+GEE +L C RF + C+ V+CS Sbjct: 306 GRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346 Score = 137 bits (344), Expect = 4e-32 Identities = 84/224 (37%), Positives = 110/224 (49%), Gaps = 23/224 (10%) Query: 156 AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH 215 A +RLV G C GRVE+ + G+WG+VCDD WD++D V+CR+LGCG A G+ Sbjct: 19 ASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGIL 78 Query: 216 FTPGRGPIHRDQ------VNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSEHQS----- 264 + P P ++Q V+C+G E L C + C H EDAGA C +S Sbjct: 79 YEP---PAEKEQKVLIQSVSCTGTEDTLAQCE-QEEVYDCSHDEDAGASCENPESSFSPV 134 Query: 265 ---WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHS 321 RL G C+G+VEV + W TVC + W AKV+C+ LGCG AV K Sbjct: 135 PEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKH 194 Query: 322 LSGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360 GR SC+G E TL +C N C+ V C Sbjct: 195 AYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC 238 >gi|222352122 hypothetical protein LOC284297 [Homo sapiens] Length = 1573 Score = 179 bits (455), Expect = 6e-45 Identities = 143/419 (34%), Positives = 173/419 (41%), Gaps = 79/419 (18%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA------SQLA 98 +RL +G C+G +EV W C WD R A CR LGCGGA AA + A Sbjct: 20 LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79 Query: 99 PPTPELPPPPAAGNTSVAANATLAGAPALLCS--------------------------GA 132 P L GN G A +CS GA Sbjct: 80 GPV-WLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGA 138 Query: 133 EWR--LCEV--------VEHACRSDG-------------RRARVTCA--------ENRAL 161 W L E+ V HA R G ++A+ T A L Sbjct: 139 PWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERL 198 Query: 162 RLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRG 221 RLV G CAGR+E+ G WG+VCDD WDL DA V CR+LGCG A+ A G F PG G Sbjct: 199 RLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAG 258 Query: 222 PIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS-EHQSWRLTGGADRCEGQVE 279 P+ D V C G E L DCP P G+ C H EDAG VC+ RL G C G++E Sbjct: 259 PVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLE 318 Query: 280 VHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEEL 335 V G W +VCD W +A V C+ LGCG A+ P G SG + C G E Sbjct: 319 VWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNET 378 Query: 336 TLSNCSWRFNNSNLCSQSLAARVLCS---------ASRSLHNLSTPEVPASVQTVTIES 385 L C R + C A +C + + N STP AS T+ S Sbjct: 379 ALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTS 437 Score = 149 bits (376), Expect = 8e-36 Identities = 97/242 (40%), Positives = 112/242 (46%), Gaps = 14/242 (5%) Query: 20 SPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAA 79 SP P +T + P + +RL +G C+G +EV W C WD R A Sbjct: 174 SPRPKQAKSTRAPLLTTGAPRQER-LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDA 232 Query: 80 EAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL-CSGAEWRLCE 138 CR LGCGGA AA A P AG + G AL C + W Sbjct: 233 AVACRELGCGGALAAPGGA------RFGPGAGPVWMDDVGCGGGEQALRDCPRSPWG--- 283 Query: 139 VVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVV 198 C V LRL DG CAGR+E+ G WGSVCDD WDL DA V Sbjct: 284 --RSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVA 341 Query: 199 CRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGA 257 CR+LGCG A+ A G F G GPI D + C G E L CP P GQH C H+EDAGA Sbjct: 342 CRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGA 401 Query: 258 VC 259 VC Sbjct: 402 VC 403 Score = 119 bits (297), Expect = 1e-26 Identities = 86/271 (31%), Positives = 107/271 (39%), Gaps = 51/271 (18%) Query: 39 PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALG----------- 87 P RL RL +G C+G +EV W C WD R A CR LG Sbjct: 300 PAPRL--RLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGA 357 Query: 88 ---------------CGGAEAASQLAPPTP-----------------ELP----PPPAAG 111 C G E A + P P +P PP A Sbjct: 358 FFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPT 417 Query: 112 NTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACA 171 +++ + A P + V A + LRLV G C+ Sbjct: 418 DSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCS 477 Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGL-HFTPGRGPIHRDQVNC 230 GR+E+ WG+VCDD+WD+ D+ VVCR+LGCG Q P F G GPI D V C Sbjct: 478 GRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGC 537 Query: 231 SGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260 G EA L DCP P G+H C H ED G C+ Sbjct: 538 VGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568 Score = 113 bits (282), Expect = 6e-25 Identities = 51/106 (48%), Positives = 65/106 (61%), Gaps = 1/106 (0%) Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220 +RL DG CAGR+E+ G WG+VCDD WDL DA V C +LGCG + H+ PG Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831 Query: 221 GPIHRDQVNCSGAEAYLWDCP-GLPGQHYCGHKEDAGAVCSEHQSW 265 GPI D + C G+EA L DCP G G+H C H+ED G C+ + + Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDY 877 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/104 (34%), Positives = 47/104 (45%), Gaps = 20/104 (19%) Query: 11 LTAALSGHPSPAPPDQLNTSSAESELWEPGERL---PVRLTNGSSSCSGTVEVRLEASWE 67 +T+ G +PP ++ + LWEPG +RL G S CSG +EV + W Sbjct: 435 MTSQAPGTAGVSPPP-----ASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWG 489 Query: 68 PACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAG 111 C WD R + VCR LGCGG + P PAAG Sbjct: 490 TVCDDSWDMRDSAVVCRELGCGGPQ------------QPDPAAG 521 Score = 56.2 bits (134), Expect = 9e-08 Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 8/81 (9%) Query: 266 RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPK-GLPHSLSG 324 RL G +RC G++EV G W TVCD W +A V C LGCG RP+ G H G Sbjct: 773 RLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKV--RPRVGKTHYGPG 830 Query: 325 R-----MYYSCNGEELTLSNC 340 C G E +LS+C Sbjct: 831 TGPIWLDDMGCKGSEASLSDC 851 Score = 45.8 bits (107), Expect = 1e-04 Identities = 52/200 (26%), Positives = 68/200 (34%), Gaps = 44/200 (22%) Query: 21 PAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAE 80 PAP ++T+ ES L+ VRL +G + C+G +EV W C WD R A Sbjct: 755 PAPSPSVSTTG-ESGLFR------VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDAT 807 Query: 81 AVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVV 140 C LGCG P G T + C G+E L + Sbjct: 808 VACWELGCGKVR---------------PRVGKTHYGPGTGPIWLDDMGCKGSEASLSD-- 850 Query: 141 EHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCR 200 C S G + C D G C G + ++ W TWD Sbjct: 851 ---CPS-GAWGKHNCDHEE-----DVGLTCTGYTDYDDYPPW------TWDPTSR----E 891 Query: 201 QLGCGWAVQALPGLHFTPGR 220 L G +PG H P R Sbjct: 892 DLAKGTTTAGVPG-HTLPWR 910 >gi|18152779 scavenger receptor cysteine rich domain containing, group B (4 domains) [Homo sapiens] Length = 575 Score = 174 bits (442), Expect = 2e-43 Identities = 144/431 (33%), Positives = 170/431 (39%), Gaps = 115/431 (26%) Query: 20 SPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAA 79 S APP L +E VRL G++ C G VE+ W C W A Sbjct: 173 SRAPPTTLPNGKSEGS---------VRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDA 223 Query: 80 EAV-----------------------------------------CRALG-----CGGAEA 93 V C++LG CG E Sbjct: 224 AVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHED 283 Query: 94 ASQLA----PPTPELPPPPA-----AGNTSVAANAT--LAGAPALLCSGAEWRLCEVVEH 142 A L PPT P A A T +A L + A W Sbjct: 284 AGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWA------- 336 Query: 143 ACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202 A + GR LRLV G G C GRVE+L G WG+VCDD WD DA V CR+ Sbjct: 337 AGKKSGR-----------LRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREA 385 Query: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSE 261 GCG A+ A HF GRGP+ D V C+G EA L DC L GQH CGH EDAGA+C+ Sbjct: 386 GCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445 Query: 262 HQS------------------------WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPS 297 + RL GA RCEG+VE++ W TVCD W Sbjct: 446 PEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLR 505 Query: 298 EAKVLCQSLGCGTAVERPKGLPHSLSGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQ 352 A VLC+ LGCG A+ P G H GR C GEE L CS +++ C Sbjct: 506 AAGVLCRQLGCGQALAAP-GEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDH 564 Query: 353 SLAARVLCSAS 363 S A VLC S Sbjct: 565 SEDASVLCQPS 575 Score = 169 bits (428), Expect = 8e-42 Identities = 134/400 (33%), Positives = 158/400 (39%), Gaps = 86/400 (21%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 +RL G S C G +EV SW C WD A VCR LGCG LA P P Sbjct: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG-------LALPVPRP 110 Query: 105 PPPPAAGNTSVAANATLAGAPALL--CSGAEWRL-----CEVVEHAC-----------RS 146 + N G A L C W + E V C + Sbjct: 111 LAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM 170 Query: 147 DGRRARVTCAEN----RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202 RA T N ++RLV G C GRVE+L G WG+VCDD W L DA VVCRQL Sbjct: 171 LTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQL 230 Query: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS- 260 GCG A+ A F G G I D V+C G E L C L G H CGH EDAGA+C+ Sbjct: 231 GCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290 Query: 261 ---------------EHQSW----------------------------------RLTGGA 271 E +W RL GG Sbjct: 291 LGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGP 350 Query: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGR-----M 326 C G+VEV G W TVCD +W ++A+V C+ GCG A+ GL H GR Sbjct: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPAL-GATGLGHFGYGRGPVLLD 409 Query: 327 YYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366 C G E LS+C + C A LC+ L Sbjct: 410 NVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEEL 449 Score = 130 bits (328), Expect = 3e-30 Identities = 93/261 (35%), Positives = 114/261 (43%), Gaps = 29/261 (11%) Query: 19 PSPAPPDQLNTSSAESELWEPGERLP-VRLTNGSSSCSGTVEVRLEASWEPACGALWDSR 77 P P+ L T++A W G++ +RL G C G VEV W C WD Sbjct: 321 PQPSRETALLTTAA----WAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFA 376 Query: 78 AAEAVCRALGCGGAEAASQLA----PPTPELPPPPAAGNTSVAANATL------------ 121 A CR GCG A A+ L P L T + Sbjct: 377 DARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHH 436 Query: 122 --AGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEH 179 AGA LC+G E +V + S+ R + LRLV+G C GRVE+ Sbjct: 437 EDAGA---LCAGPEELGLQVQQDG--SETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLG 491 Query: 180 GEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWD 239 WG+VCDD WDL A V+CRQLGCG A+ A HF PGRGPI D V C G E+ L Sbjct: 492 QRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLL 551 Query: 240 CPGLP-GQHYCGHKEDAGAVC 259 C + H C H EDA +C Sbjct: 552 CSHIRWDAHNCDHSEDASVLC 572 Score = 68.9 bits (167), Expect = 1e-11 Identities = 39/103 (37%), Positives = 50/103 (48%), Gaps = 6/103 (5%) Query: 263 QSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL 322 Q RL GG RC G++EV G W +VCD +W +A V+C+ LGCG A+ P+ L Sbjct: 56 QELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG- 114 Query: 323 SGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360 GR C G+E LS C R + C VLC Sbjct: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157 >gi|4506143 neurotrypsin precursor [Homo sapiens] Length = 875 Score = 170 bits (431), Expect = 3e-42 Identities = 114/344 (33%), Positives = 151/344 (43%), Gaps = 36/344 (10%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 VRL G + GTVEV W C + WD A +C L GG A Q Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQT------- 222 Query: 105 PPPPAAGNTSVA---ANATLAGAPA--LLCSGAEWR--LCEVVEHACRSDGRRARVTCAE 157 P +G + +N G LLC W+ +C A VTC+ Sbjct: 223 ---PFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCP--------QKMAAAVTCSF 271 Query: 158 NRA-----LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212 + +RL G GRVE+ G+WG+VCDD WD DA V+CRQLG +A Sbjct: 272 SHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWH 331 Query: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSW--RLTG 269 +F G GP+ D+V C+G E + CP G+H CGHKEDAG C+ RL G Sbjct: 332 QAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAG 391 Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMY-- 327 G EG++EV++RG W TVCD W V+C+ LG + +G ++ Sbjct: 392 GKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTGPIWLD 451 Query: 328 -YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370 SC+G+E CS R + CS + C H LS Sbjct: 452 DVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLS 495 Score = 149 bits (375), Expect = 1e-35 Identities = 109/332 (32%), Positives = 142/332 (42%), Gaps = 28/332 (8%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 +RL GSS G VE+ W C WD AE +CR LG G A A E Sbjct: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAY-FGEG 338 Query: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAE--NRALR 162 P N C + W EH C A V+C + +R Sbjct: 339 SGPVMLDEVRCTGNELSIEQ----CPKSSWG-----EHNC-GHKEDAGVSCTPLTDGVIR 388 Query: 163 LVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGP 222 L G G+ GR+E+ G+WG+VCDD W + +VVCRQLG + QA HF GP Sbjct: 389 LAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGP 447 Query: 223 IHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVC---------SEHQSWRLTGGAD 272 I D V+CSG E C G+H C H+ED C S RL G + Sbjct: 448 IWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGEN 507 Query: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC-GTAVERPKGLPHSLSGRMY---Y 328 + EG+VEV G W T+CD W +A V+C+ LG G A R G ++ Sbjct: 508 KKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNV 567 Query: 329 SCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360 C G E +L++C + + C S A V+C Sbjct: 568 KCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599 Score = 92.4 bits (228), Expect = 1e-18 Identities = 71/215 (33%), Positives = 94/215 (43%), Gaps = 16/215 (7%) Query: 160 ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219 ++RL G G VE+ G WG+VC WD DA V+C QL G A G Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPGQ-HYCGHKEDAGAVCSEHQS-----WRLTGGADR 273 PI+ V C G E + C Q C K A CS RL GG+ Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSV 288 Query: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLG-CGTAVERPKGLPHSLSGRMYYS--- 329 EG+VE++ G W TVCD +W ++A+V+C+ LG G A + SG + Sbjct: 289 HEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVR 348 Query: 330 CNGEELTLSNC---SWRFNNSNLCSQSLAARVLCS 361 C G EL++ C SW +N C A V C+ Sbjct: 349 CTGNELSIEQCPKSSWGEHN---CGHKEDAGVSCT 380 Score = 69.3 bits (168), Expect = 1e-11 Identities = 47/122 (38%), Positives = 58/122 (47%), Gaps = 16/122 (13%) Query: 252 KEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSL---GC 308 K D G H S RL GG + EG VEV+ GVW TVC S W S+A V+C L G Sbjct: 157 KVDWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGK 216 Query: 309 GTAVERPKGLPHSLSG----RMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361 G A + P SG +Y+S C G+E + C +C Q +AA V CS Sbjct: 217 GIAKQTP------FSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCS 270 Query: 362 AS 363 S Sbjct: 271 FS 272 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/55 (36%), Positives = 26/55 (47%) Query: 44 PVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98 PVRL +G + G VEV + W C W + A +CR LG G A +A Sbjct: 499 PVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMA 553 >gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] Length = 753 Score = 135 bits (340), Expect = 1e-31 Identities = 109/360 (30%), Positives = 147/360 (40%), Gaps = 63/360 (17%) Query: 56 GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSV 115 G VEVRL W C W + + VC LG + + + G V Sbjct: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246 Query: 116 AANATLAGAPALLCSGAEWRLCEVVE----------------HACRSDGRRARVTCAENR 159 A T A LCS +R + +A S ++ + + + Sbjct: 247 ACVGTEAHLS--LCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGE 304 Query: 160 A-LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 A +RL G GRVE+L+ WG+VCD WDL A VVCR+LG G A +AL G Sbjct: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364 Query: 219 GRGPIHRDQVNCSGAEAYLWDCP--GLPGQHYCGHKEDAGAVCS-----EHQSWRLTGGA 271 G G IH +V CSG E LW CP + + C H +DAG C+ RL+GG Sbjct: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAED-CSHSQDAGVRCNLPYTGAETRIRLSGGR 423 Query: 272 DRCEGQVEVHFRGV----WNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMY 327 + EG+VEV G W +C +W EA V C+ LG G A H L Y Sbjct: 424 SQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYA-------NHGLQETWY 476 Query: 328 YS-------------CNGEELTLSNCS------------WRFNNSNLCSQSLAARVLCSA 362 + C G EL+L C+ RF +CS++ + +L SA Sbjct: 477 WDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSA 536 Score = 98.6 bits (244), Expect = 2e-20 Identities = 67/214 (31%), Positives = 90/214 (42%), Gaps = 40/214 (18%) Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231 GRVE+ GEWG++CDD + L+ AH++CR+LG A + PG G I D ++CS Sbjct: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115 Query: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGADR----------------- 273 G E + +C G C H EDAG +C + RL G +D Sbjct: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQ---RLPGFSDSNVIEVEHHLQVEEVRIR 172 Query: 274 ------------CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHS 321 EG VEV W+ VCD W + V+C LG + Sbjct: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRL 232 Query: 322 LSGRMYYS-------CNGEELTLSNCSWRFNNSN 348 L+ R +S C G E LS CS F +N Sbjct: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRAN 266 Score = 79.3 bits (194), Expect = 1e-14 Identities = 75/264 (28%), Positives = 98/264 (37%), Gaps = 37/264 (14%) Query: 21 PAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAE 80 P P ++ + + +P VRL G+ G VEV ++W C WD AA Sbjct: 283 PGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAAS 342 Query: 81 AVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCE-- 138 VCR LG G A A + + CSG E L + Sbjct: 343 VVCRELGFGSAR---------------EALSGARMGQGMGAIHLSEVRCSGQELSLWKCP 387 Query: 139 ---VVEHACRSDGRRARVTC------AENRALRLVDGGGACAGRVEMLEHG----EWGSV 185 + C S + A V C AE R +RL G GRVE+ G WG + Sbjct: 388 HKNITAEDC-SHSQDAGVRCNLPYTGAETR-IRLSGGRSQHEGRVEVQIGGPGPLRWGLI 445 Query: 186 CDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRG--PIHRDQVNCSGAEAYLWDCPGL 243 C D W +A V CRQLG G+A L + + V C+G E L C Sbjct: 446 CGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH 505 Query: 244 PGQHYC---GHKEDAGAVCSEHQS 264 C G + AG +CSE S Sbjct: 506 GTHITCKRTGTRFTAGVICSETAS 529 Score = 52.0 bits (123), Expect = 2e-06 Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 21/161 (13%) Query: 240 CPGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADR-CEGQVEVHFRGVWNTVCDSEWYPSE 298 C G P G ++ AG S+ +RL G + EG+VE+ G W T+CD ++ Sbjct: 23 CLGSPSPS-TGPEKKAG---SQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQA 78 Query: 299 AKVLCQSLGCGTAVERPKGLPHSL-----SGRMY---YSCNGEELTLSNCSWRFNNSNLC 350 A +LC+ LG A G HS +GR++ SC+G E +++ C+ R ++ C Sbjct: 79 AHILCRELGFTEAT----GWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDC 134 Query: 351 SQSLAARVLCSASR----SLHNLSTPEVPASVQTVTIESSV 387 + A V+C R S N+ E V+ V I +V Sbjct: 135 THDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175 >gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] Length = 756 Score = 134 bits (337), Expect = 3e-31 Identities = 109/334 (32%), Positives = 136/334 (40%), Gaps = 52/334 (15%) Query: 56 GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGG-AEAASQLAPPTPELPPPPAAGNTS 114 G VEV+ E W C W + VC LG S +L Sbjct: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236 Query: 115 VAANATLAGAPALLCSGAEWRL--CEVVEHACRSD-------GRRARVTC---------- 155 N + C G E + C+V R G A V+C Sbjct: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK 296 Query: 156 ---------AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206 AE +RL G GRVE+L + +WG+VCD W+L A VVCRQLG G Sbjct: 297 TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGS 356 Query: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSE---- 261 A +AL G G GPIH +V C G E L DCP L G Q+ C H+ DA C+ Sbjct: 357 AREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMG 416 Query: 262 -HQSWRLTGGADRCEG--QVEVHFRGV--WNTVCDSEWYPSEAKVLCQSLGCGTAVERPK 316 RL GG EG +V+V GV W +VC W +EA V C+ LG G A+ K Sbjct: 417 FQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYK 476 Query: 317 ------GLPHS----LSGRMYYSCNGEELTLSNC 340 G P + +SG C+G EL L C Sbjct: 477 ETWFWSGTPRAQEVVMSG---VRCSGTELALQQC 507 Score = 92.0 bits (227), Expect = 2e-18 Identities = 67/218 (30%), Positives = 91/218 (41%), Gaps = 49/218 (22%) Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231 GR+E+L G+WG+VCDD + +++A V CRQLG A+ + G GPI D V C Sbjct: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103 Query: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVC---------SEHQSWRLTGGADR-------- 273 G E+ L C G C H ED G +C SE S L R Sbjct: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKP 163 Query: 274 -----------CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV---------- 312 EG VEV + G W VCD W + ++V+C LG + V Sbjct: 164 ILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKV 223 Query: 313 -----ERPKGLPHSLSGRMYY-----SCNGEELTLSNC 340 PK SL+ + + +C G E ++NC Sbjct: 224 WDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANC 261 Score = 81.3 bits (199), Expect = 3e-15 Identities = 68/212 (32%), Positives = 88/212 (41%), Gaps = 10/212 (4%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104 VRL +G+ G VEV + W C W+ +A VCR LG G A A A L Sbjct: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370 Query: 105 PPPPAAGNTSVAANATLAGAPALLCS--GAEWRLCEVVEHACRSDGRRARVTCAENRALR 162 P + TL+ PAL S G + V + G + +V A R Sbjct: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGR--- 427 Query: 163 LVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF---TPG 219 + G +VE+ WGSVC + W L +A V CRQLG G+A+ A F TP Sbjct: 428 -IPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486 Query: 220 RGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGH 251 + V CSG E L C G +C H Sbjct: 487 AQEVVMSGVRCSGTELALQQCQ-RHGPVHCSH 517 Score = 79.0 bits (193), Expect = 1e-14 Identities = 103/418 (24%), Positives = 137/418 (32%), Gaps = 78/418 (18%) Query: 8 TGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCS-GTVEVRLEASW 66 T L L G P P+ P L T+ +RL S G +EV + W Sbjct: 8 TLFLFLLLLGQPPPSRPQSLGTTK-------------LRLVGPESKPEEGRLEVLHQGQW 54 Query: 67 EPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPP---------------PPAAG 111 C + + A CR LG A + A P Sbjct: 55 GTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGS 114 Query: 112 NTSVAANATLAGAPALLCSGAEWR--LCEVVEHACRSDGRRARVTCAENRALRLVDGGGA 169 N ++ + + ++C R L E V +A GRR + Sbjct: 115 NGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPV 174 Query: 170 CAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQA----------------LPG 213 G VE+ G W VCD W + ++ VVC LG V Sbjct: 175 TEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSR 234 Query: 214 LHFTPGRGPIHRDQVNCSGAEAYLWDC------------PGLPGQHYC-------GHKED 254 L + QV C G E ++ +C P PG + H Sbjct: 235 LKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP 294 Query: 255 AGAVCSEHQSW------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC 308 SW RL GA EG+VEV W TVCD W A V+C+ LG Sbjct: 295 PKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGF 354 Query: 309 GTAVERPKG--LPHSLSGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361 G+A E G L L G ++ S C G E TLS+C + N C A V C+ Sbjct: 355 GSAREALFGARLGQGL-GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 4/100 (4%) Query: 275 EGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---C 330 EG++EV +G W TVCD + EA V C+ LG A+ + G ++ C Sbjct: 43 EGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRC 102 Query: 331 NGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370 G E +L C + CS S V+C R LS Sbjct: 103 VGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLS 142 >gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] Length = 774 Score = 130 bits (328), Expect = 3e-30 Identities = 102/321 (31%), Positives = 143/321 (44%), Gaps = 39/321 (12%) Query: 56 GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGG-----AEAASQLAPPTPELPPPPAA 110 G VEV+ +W+ C W ++ + VC G G + A + P + Sbjct: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263 Query: 111 GNTSVAANATLAG-APALLCSGAEWRLCE---------VVEHACRSDG--RRARVTCAEN 158 T A+ + P + + CE V DG R + E Sbjct: 264 DCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQ 323 Query: 159 RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218 +RL G GRVE+L++GEWG+VCDD WDL A VVCR+LG G A +A+ G Sbjct: 324 PLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 383 Query: 219 GRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSE-----HQSWRLTGGADR 273 G GPIH +++ C+G E + DC C H+EDAG C+ + RL GG + Sbjct: 384 GIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNP 443 Query: 274 CEGQVEVHFRG----VWNTVCDSEWYPSEAKVLCQSLGCGTAVERPK------GLPHS-- 321 EG+VEV VW VC W EA V+C+ LG G A + G +S Sbjct: 444 YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503 Query: 322 --LSGRMYYSCNGEELTLSNC 340 +SG C+G EL+L++C Sbjct: 504 VVMSG---VKCSGTELSLAHC 521 Score = 84.0 bits (206), Expect = 4e-16 Identities = 63/209 (30%), Positives = 81/209 (38%), Gaps = 43/209 (20%) Query: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231 GRVE+ G+WG+VCDD + + AHVVCR+LG A + G GPI D ++C+ Sbjct: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129 Query: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTG--------------------- 269 G EA L C G C H ED G VCS+ R+ G Sbjct: 130 GNEATLAACTSNGWGVTDCKHTEDVGVVCSDK---RIPGFKFDNSLINQIENLNIQVEDI 186 Query: 270 -----------GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC-GTAVERPKG 317 EG VEV W +CD W ++V+C G G K Sbjct: 187 RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKV 246 Query: 318 LPHSLSGR------MYYSCNGEELTLSNC 340 S R C G E +S+C Sbjct: 247 YKMFASRRKQRYWPFSMDCTGTEAHISSC 275 Score = 71.6 bits (174), Expect = 2e-12 Identities = 98/369 (26%), Positives = 137/369 (37%), Gaps = 76/369 (20%) Query: 56 GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPA-AGNTS 114 G VEV + W C + AA VCR LG EA S A + P N Sbjct: 70 GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGY--VEAKSWTASSSYGKGEGPIWLDNLH 127 Query: 115 VAAN-ATLAGAPALLCSGAEWRLCEVVEHACRSDGR-------RARVTCAENRALRLVD- 165 N ATLA + + + E V C SD R + + EN +++ D Sbjct: 128 CTGNEATLAACTSNGWGVTDCKHTEDVGVVC-SDKRIPGFKFDNSLINQIENLNIQVEDI 186 Query: 166 -----------GGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPG- 213 G VE+ E W +CD W +++ VVC G PG Sbjct: 187 RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG-------FPGE 239 Query: 214 ---------LHFTPGRGPIHRDQVNCSGAEAYLWDCP-----------------GLPGQH 247 + + + ++C+G EA++ C GLP Sbjct: 240 RTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299 Query: 248 YC---------GHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298 C G A E RL GGA EG+VEV G W TVCD +W Sbjct: 300 SCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVS 359 Query: 299 AKVLCQSLGCGTAVERPKG--LPHSLSGRMYYS---CNGEELTLSNCSWRFN-NSNLCSQ 352 A V+C+ LG G+A E G L + G ++ + C G E ++ +C +FN S C+ Sbjct: 360 ASVVCRELGFGSAKEAVTGSRLGQGI-GPIHLNEIQCTGNEKSIIDC--KFNAESQGCNH 416 Query: 353 SLAARVLCS 361 A V C+ Sbjct: 417 EEDAGVRCN 425 Score = 71.6 bits (174), Expect = 2e-12 Identities = 73/233 (31%), Positives = 87/233 (37%), Gaps = 29/233 (12%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA---SQLAPPT 101 VRL G+ G VEV W C WD +A VCR LG G A+ A S+L Sbjct: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385 Query: 102 P--ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARV-TCAEN 158 L GN + AE + C E A G R Sbjct: 386 GPIHLNEIQCTGNEKSIIDCKF---------NAESQGCNHEEDA----GVRCNTPAMGLQ 432 Query: 159 RALRLVDGGGACAGRVEMLEHGE----WGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGL 214 + LRL G GRVE+L WG VC W + +A VVCRQLG G+A A Sbjct: 433 KKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQET 492 Query: 215 HFTPG---RGPIHRDQVNCSGAEAYLWDCPGLPGQHYC---GHKEDAGAVCSE 261 + G + V CSG E L C C G + AG CSE Sbjct: 493 WYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSE 545 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 10/97 (10%) Query: 275 EGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGR-------MY 327 EG+VEV++ G W TVCD ++ A V+C+ LG VE S G+ Sbjct: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELG---YVEAKSWTASSSYGKGEGPIWLDN 125 Query: 328 YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364 C G E TL+ C+ C + V+CS R Sbjct: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKR 162 Score = 36.6 bits (83), Expect = 0.077 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 4/61 (6%) Query: 40 GERLPVRLTNGSSSCSGTVEVRLEAS----WEPACGALWDSRAAEAVCRALGCGGAEAAS 95 G + +RL G + G VEV +E + W CG W A VCR LG G A A Sbjct: 430 GLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAF 489 Query: 96 Q 96 Q Sbjct: 490 Q 490 >gi|5031863 galectin 3 binding protein [Homo sapiens] Length = 585 Score = 102 bits (254), Expect = 1e-21 Identities = 52/101 (51%), Positives = 62/101 (61%), Gaps = 1/101 (0%) Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220 +RL DGG GRVE+ G+WG+VCD+ WDL DA VVCR LG A QAL F G Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83 Query: 221 GPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260 GPI D+V C+G EA L DC L + C H+ DAG VC+ Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124 Score = 54.7 bits (130), Expect = 3e-07 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 17/115 (14%) Query: 266 RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGR 325 RL G +G+VE+ +RG W TVCD+ W ++A V+C++LG A + L + G+ Sbjct: 25 RLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQ---ALGRAAFGQ 81 Query: 326 -------MYYSCNGEELTLSNC---SWRFNNSNLCSQSLAARVLC-SASRSLHNL 369 C G E +L++C W +N C A V+C + +RS H L Sbjct: 82 GSGPIMLDEVQCTGTEASLADCKSLGWLKSN---CRHERDAGVVCTNETRSTHTL 133 Score = 42.0 bits (97), Expect = 0.002 Identities = 20/50 (40%), Positives = 25/50 (50%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94 +RL +G ++ G VE+ W C LWD A VCRALG A A Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQA 73 >gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens] Length = 782 Score = 89.4 bits (220), Expect = 1e-17 Identities = 57/129 (44%), Positives = 72/129 (55%), Gaps = 10/129 (7%) Query: 145 RSDGRRARVTCAENRA-----LRLVDGGGACAG--RVEMLEHGEWGSVCDDTWDLEDAHV 197 R GRR + +RA +RLV G +G RVE+ G WG+VCDD+W++ A V Sbjct: 652 RGGGRRRGRLNSASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAV 711 Query: 198 VCRQLGCGWAVQALPGLHFTPGRG-PIHRDQVNCSGAEAYLWDCP-GLPGQHYCGHKEDA 255 VCRQLG +AV+A+ F G PI D V C+G E L +C G H C H EDA Sbjct: 712 VCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDA 771 Query: 256 GAVCSEHQS 264 G VCS HQ+ Sbjct: 772 GVVCS-HQN 779 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 5/97 (5%) Query: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRM--- 326 G G+VEV G W TVCD W S A V+C+ LG AV K G + Sbjct: 680 GLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPIL 739 Query: 327 --YYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361 C G E L C ++ C A V+CS Sbjct: 740 LDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776 Score = 35.8 bits (81), Expect = 0.13 Identities = 31/91 (34%), Positives = 37/91 (40%), Gaps = 12/91 (13%) Query: 19 PSPAPPDQLNTS-----------SAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWE 67 P PA P Q S ++ S + GE VR G SS SG VEV + W Sbjct: 639 PRPARPTQQPGSRRGGGRRRGRLNSASRAFRDGEVRLVRPA-GLSSGSGRVEVFVGGRWG 697 Query: 68 PACGALWDSRAAEAVCRALGCGGAEAASQLA 98 C W+ A VCR LG A A + A Sbjct: 698 TVCDDSWNISGAAVVCRQLGFAYAVRAVKRA 728 >gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo sapiens] Length = 451 Score = 86.3 bits (212), Expect = 8e-17 Identities = 42/101 (41%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220 +RLV G G GRVE+L G+WG++CDD W++ VVCR LG HF G Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409 Query: 221 GPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS 260 GPI ++V C G E+ + +C G C H EDAG C+ Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450 Score = 53.5 bits (127), Expect = 6e-07 Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 4/125 (3%) Query: 241 PGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK 300 PG G ++ +G + RL GG+ EG+VE+ G W T+CD W + Sbjct: 326 PGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQ 385 Query: 301 VLCQSLGC-GTAVERPKGLPHSLSGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAA 356 V+C+SLG G +G ++ + C G E ++ C R + CS S A Sbjct: 386 VVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDA 445 Query: 357 RVLCS 361 V C+ Sbjct: 446 GVTCT 450 Score = 43.1 bits (100), Expect = 8e-04 Identities = 20/54 (37%), Positives = 26/54 (48%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98 VRL GS G VE+ W C W+ R + VCR+LG G +A + A Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAA 403 >gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] Length = 495 Score = 84.0 bits (206), Expect = 4e-16 Identities = 43/103 (41%), Positives = 52/103 (50%), Gaps = 1/103 (0%) Query: 161 LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220 +RLV+G G GRVE+ WG+VCDD WD +D VVCR LG + F G Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452 Query: 221 GPIHRDQVNCSGAEAYLWDCP-GLPGQHYCGHKEDAGAVCSEH 262 G I D V C G E ++ C G CGH EDA C+ H Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCNRH 495 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 4/100 (4%) Query: 266 RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SG 324 RL G+ EG+VEV+ W TVCD W + V+C+ LG E + +G Sbjct: 394 RLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGTG 453 Query: 325 RMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361 R++ +C G E T+ CS+ C + A V C+ Sbjct: 454 RIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493 Score = 43.5 bits (101), Expect = 6e-04 Identities = 21/54 (38%), Positives = 26/54 (48%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLA 98 +RL NGS G VEV + W C WD + + VCR LG G E + A Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTA 446 >gi|5803080 macrophage receptor with collagenous structure [Homo sapiens] Length = 520 Score = 74.7 bits (182), Expect = 3e-13 Identities = 41/97 (42%), Positives = 49/97 (50%), Gaps = 8/97 (8%) Query: 167 GGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGC--GWAVQALPGLHFTPGRGPIH 224 G + GR E+ G WG++CDD W DA V CR LG G A+ + G G I Sbjct: 428 GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGA-----GTGQIW 482 Query: 225 RDQVNCSGAEAYLWDC-PGLPGQHYCGHKEDAGAVCS 260 D V C G E+ LW C G H C H+EDAG CS Sbjct: 483 LDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 Score = 54.3 bits (129), Expect = 4e-07 Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 7/115 (6%) Query: 250 GHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309 G K + G S R+ G ++R G+ EV++ G W T+CD EW S+A V C+ LG Sbjct: 409 GVKGEKGERGENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYS 466 Query: 310 TAVERPKGLPHSLSGRMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361 R + +G+++ C G E TL +C+ + CS A V CS Sbjct: 467 KG--RALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519 >gi|166197668 CD5 molecule [Homo sapiens] Length = 495 Score = 61.6 bits (148), Expect = 2e-09 Identities = 85/313 (27%), Positives = 113/313 (36%), Gaps = 73/313 (23%) Query: 46 RLTNGSSSCSGTVEVRLEASWEPACGALW--------DSRAAEAVCRALGCGGAEAASQL 97 RLT +S C G +EV L+ W C W D A VC+ L CG L Sbjct: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCG---VPLSL 92 Query: 98 APPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRS-------DGRR 150 P P +S+ L CS + +C + C R Sbjct: 93 GPFLVTYTP-----QSSIICYGQLGSFSN--CSHSRNDMCHSLGLTCLEPQKTTPPTTRP 145 Query: 151 ARVTCAENRA---LRLV--DGGGACAGRVEMLEHGEWGSVC----DDTWDLEDAHVVCRQ 201 T E A L+LV GG CAG VE G++ D T DLE + +C Sbjct: 146 PPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLE--NFLCNN 203 Query: 202 LGCGWAVQALP----GLHFTPGRGPIHR--------DQVNCSGAEAYLWDCPGLPGQHYC 249 L CG ++ LP G PG H+ +C+ E +C Sbjct: 204 LQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLE-------------HC 250 Query: 250 GHK---EDAGAV----CSEHQ---SWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEA 299 K + +G V CS Q RL GG+ CEG VEV W +CDS S Sbjct: 251 FRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSL 310 Query: 300 K--VLCQSLGCGT 310 + +C+ CG+ Sbjct: 311 RWEEVCREQQCGS 323 Score = 49.3 bits (116), Expect = 1e-05 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 16/105 (15%) Query: 257 AVCSEHQSW-------RLTGGADRCEGQVEVHFRGVWNTVCDSEW--------YPSEAKV 301 A C SW RLT +C+GQ+EV+ + W+ VC W PS+A Sbjct: 20 ASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASK 79 Query: 302 LCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNN 346 +CQ L CG + L + + + C G+ + SNCS N+ Sbjct: 80 VCQRLNCGVPLSLGPFLV-TYTPQSSIICYGQLGSFSNCSHSRND 123 Score = 39.7 bits (91), Expect = 0.009 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 46 RLTNGSSSCSGTVEVRLEASWEPAC--GALWDSRAAEAVCRALGCGGAEA 93 RL GSS C GTVEVR A W C + S E VCR CG + Sbjct: 277 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNS 326 >gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2 [Homo sapiens] Length = 387 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/186 (22%), Positives = 66/186 (35%), Gaps = 20/186 (10%) Query: 467 PIQVQAPPPEDSDSGSDSDYEHYDFSAQPPVALTTFYNSQRHRVTDEEVQQSR--FQMPP 524 P+ Q PP + + +HY QPP+ + N H + ++ R Q PP Sbjct: 204 PMMHQQPPSQQYNMPQGGG-QHYQ-GQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPP 261 Query: 525 LE-EGLEELHASHIPTANPGHCITDPPSLGPQYHPRSNSESSTSSGEDYCNSPKSKLPPW 583 + G E+ + G P + QY+P NS+ P+ PP Sbjct: 262 QQYSGQEDYYGDQYSHGGQG----PPEGMNQQYYPDGNSQYGQQQDAYQGPPPQQGYPPQ 317 Query: 584 NPQVFSSERSSFLEQPPNLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQP----PPQPP 639 Q + +Q G P+ P + G+ Y ++P PPQPP Sbjct: 318 QQQYPGQQGYPGQQQ-------GYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPP 370 Query: 640 SEEQFG 645 + +G Sbjct: 371 QQRPYG 376 >gi|223942069 enterokinase precursor [Homo sapiens] Length = 1019 Score = 41.6 bits (96), Expect = 0.002 Identities = 16/53 (30%), Positives = 30/53 (56%) Query: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQL 97 VR NG+++ +G V R+++ W AC W ++ + VC+ LG G ++ + Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPI 730 Score = 33.1 bits (74), Expect = 0.85 Identities = 23/92 (25%), Positives = 31/92 (33%), Gaps = 13/92 (14%) Query: 222 PIHRDQVNCSGAEAYLWDCPGLPGQHYCG---HKEDAGAVCSEHQSWRLTGGADRCEGQV 278 P D C E +P + C H ED E R G G V Sbjct: 642 PCKADHFQCKNGEC-------VPLVNLCDGHLHCEDGS---DEADCVRFFNGTTNNNGLV 691 Query: 279 EVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGT 310 + +W+T C W + +CQ LG G+ Sbjct: 692 RFRIQSIWHTACAENWTTQISNDVCQLLGLGS 723 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 41.6 bits (96), Expect = 0.002 Identities = 40/167 (23%), Positives = 60/167 (35%), Gaps = 10/167 (5%) Query: 500 TTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPP--SLGPQYH 557 T +YN Q ++ S Q PP + + P + P + P S P Sbjct: 468 TPYYNQQSPHPQQQQPPYS--QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP 525 Query: 558 PRSNSESSTSSGEDYCNSPKSKLPPWN-PQVFSSERSSFLEQPPNLELAGTQPAFSAGPP 616 P S + S + PP++ PQ +S + +Q P T +A P Sbjct: 526 PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA----QSPYQQQQPQQPAPSTLSQQAAYPQ 581 Query: 617 ADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDNDDYD 663 S + Q F PPPQ S++ FG S +P S+ D Sbjct: 582 PQSQQSQQTAYSQQRF-PPPQELSQDSFGSQASSAPSMTSSKGGQED 627 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 41.6 bits (96), Expect = 0.002 Identities = 40/167 (23%), Positives = 60/167 (35%), Gaps = 10/167 (5%) Query: 500 TTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPP--SLGPQYH 557 T +YN Q ++ S Q PP + + P + P + P S P Sbjct: 468 TPYYNQQSPHPQQQQPPYS--QQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP 525 Query: 558 PRSNSESSTSSGEDYCNSPKSKLPPWN-PQVFSSERSSFLEQPPNLELAGTQPAFSAGPP 616 P S + S + PP++ PQ +S + +Q P T +A P Sbjct: 526 PHQQSPAPYPSQQSTTQQHPQSQPPYSQPQA----QSPYQQQQPQQPAPSTLSQQAAYPQ 581 Query: 617 ADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDSTDNDDYD 663 S + Q F PPPQ S++ FG S +P S+ D Sbjct: 582 PQSQQSQQTAYSQQRF-PPPQELSQDSFGSQASSAPSMTSSKGGQED 627 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 40.8 bits (94), Expect = 0.004 Identities = 42/163 (25%), Positives = 61/163 (37%), Gaps = 26/163 (15%) Query: 515 VQQSRFQMPP------LEEGLEELHAS--HIPTANPGH---CITDPPSLGPQYHPRSN-S 562 +QQ Q P L + L+++H + H P P P L PQ + S Sbjct: 270 IQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS 329 Query: 563 ESSTSSGEDYCNSPKSKL---------PPWNPQVFSSERSSFLEQPPNLELAGTQPAFSA 613 ++ G+ P K PP PQV + + Q + G Q + S+ Sbjct: 330 QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSS 389 Query: 614 GPPADDSSSTSSGEWYQNFQPPPQPPSEEQFGCPGSPSPQPDS 656 P S + Q+ PPPQP + PG PS QP+S Sbjct: 390 LPMLSSPSPGQQVQTPQSMPPPPQPSPQ-----PGQPSSQPNS 427 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 39.7 bits (91), Expect = 0.009 Identities = 46/200 (23%), Positives = 65/200 (32%), Gaps = 14/200 (7%) Query: 454 PVPIT-IPKEVFMLPIQVQAPPPEDSDSGSDSDYEHYDFSAQPPVALTTFYNSQRHRVTD 512 P P++ +P V + Q PP + + + Q P A+ + + + Sbjct: 852 PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA---KPKWQPSS 908 Query: 513 EEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPPSLGPQYHPRSNSESSTSSGEDY 572 V F PP E L P P PP P P + S Sbjct: 909 IPVPSPDFPPPPPESSLV------FPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSK 962 Query: 573 CNSPKSKLPPWNPQVFSSERSSFLEQPPNLELAGTQPAFSAGPPADDSSSTSSGEWYQNF 632 +SP K PP PQ SS +SS + P + S P +S S S + Sbjct: 963 TSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK----ETL 1018 Query: 633 QPPPQPPSEEQFGCPGSPSP 652 PP PP + G P Sbjct: 1019 PPPAAPPKPGKLNLSGVNLP 1038 Score = 30.4 bits (67), Expect = 5.5 Identities = 35/130 (26%), Positives = 47/130 (36%), Gaps = 23/130 (17%) Query: 534 ASHIPTANPGHCITDPPSLGPQYHPRSNSESSTSSGEDYC-NSPKSKLPPWNPQVFSSER 592 AS+IP + P T P + P P+ S +C P S L P P V Sbjct: 821 ASYIPPSPP----TPPVPVPPPTLPKQQS---------FCAKPPPSPLSPV-PSVVKQIA 866 Query: 593 SSFLEQP--PNLELAGTQPAFSAGPPADDSSSTSSGEWYQNFQP------PPQPPSEEQF 644 S F P P +E +P + P + + +W + P PP PP Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926 Query: 645 GCPGSPSPQP 654 P PSP P Sbjct: 927 FPPPPPSPVP 936 >gi|15529996 son of sevenless homolog 1 [Homo sapiens] Length = 1333 Score = 39.3 bits (90), Expect = 0.012 Identities = 49/193 (25%), Positives = 73/193 (37%), Gaps = 24/193 (12%) Query: 441 LPTTIPAGSNSYQPVPITIPKEVFMLPIQVQAPP---PEDSDSGSDSDY---EHYDFS-A 493 + T+P G S I++ K +P+ PP PE + + S +H D A Sbjct: 1122 IQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPA 1181 Query: 494 QPPVALTTFYNSQRHRVTDEEVQQSRFQMPPLEEGLEELHASHIPTANPGHCITDPPSLG 553 PP T+ S R+ ++D + PPL E + + +++P H PP LG Sbjct: 1182 IPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLH--LQPPPLG 1239 Query: 554 PQYHPRSNSESSTSSGEDYCNSPK--SKLPPWNPQVFSSERSSFLEQPPNLELAGTQPAF 611 + S + NSP + PP P + R L PP + Sbjct: 1240 ---------KKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRR--HLPSPPLTQEVDLHSI- 1287 Query: 612 SAGPPADDSSSTS 624 AGPP STS Sbjct: 1288 -AGPPVPPRQSTS 1299 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,954,105 Number of Sequences: 37866 Number of extensions: 1934998 Number of successful extensions: 10484 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 295 Number of HSP's that attempted gapping in prelim test: 8916 Number of HSP's gapped (non-prelim): 1557 length of query: 668 length of database: 18,247,518 effective HSP length: 109 effective length of query: 559 effective length of database: 14,120,124 effective search space: 7893149316 effective search space used: 7893149316 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.