Guide to the Human Genome
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Search of human proteins with 187829730

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]        560   e-160
gi|187829745 BCL2 binding component 3 isoform 3 [Homo sapiens]        154   1e-37
gi|187829742 BCL2 binding component 3 isoform 2 [Homo sapiens]         80   2e-15
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    64   1e-10
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     62   7e-10
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   60   2e-09
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                   60   2e-09
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                59   3e-09
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      58   7e-09
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     58   7e-09
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   57   1e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    56   3e-08
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          56   4e-08
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   55   5e-08
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    55   8e-08
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ...    55   8e-08
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]            55   8e-08
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        55   8e-08
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    54   1e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    54   1e-07
gi|113427525 PREDICTED: similar to hCG2037003 [Homo sapiens]           54   1e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    54   1e-07
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    54   1e-07
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    54   1e-07
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    53   2e-07
gi|21955170 single stranded DNA binding protein 3 isoform a [Hom...    53   2e-07
gi|58218981 single stranded DNA binding protein 3 isoform c [Hom...    53   2e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    53   3e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      52   4e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    52   4e-07

>gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]
          Length = 261

 Score =  560 bits (1444), Expect = e-160
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MKFGMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLP 60
           MKFGMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLP
Sbjct: 1   MKFGMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLP 60

Query: 61  ARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAP 120
           ARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAP
Sbjct: 61  ARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAP 120

Query: 121 RPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGG 180
           RPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGG
Sbjct: 121 RPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGG 180

Query: 181 RPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDS 240
           RPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDS
Sbjct: 181 RPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDS 240

Query: 241 GGRPLPPPDTLASAGDFLCTM 261
           GGRPLPPPDTLASAGDFLCTM
Sbjct: 241 GGRPLPPPDTLASAGDFLCTM 261


>gi|187829745 BCL2 binding component 3 isoform 3 [Homo sapiens]
          Length = 101

 Score =  154 bits (388), Expect = 1e-37
 Identities = 72/72 (100%), Positives = 72/72 (100%)

Query: 190 ETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPPD 249
           ETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPPD
Sbjct: 30  ETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPPD 89

Query: 250 TLASAGDFLCTM 261
           TLASAGDFLCTM
Sbjct: 90  TLASAGDFLCTM 101



 Score = 75.5 bits (184), Expect = 4e-14
 Identities = 45/93 (48%), Positives = 48/93 (51%), Gaps = 24/93 (25%)

Query: 1  MKFGMGSAQACPCQVPRAASTTWVPCQIC--------------GPRERH--------GPR 38
          MKFGMGSAQACPCQVPRAASTTWVPCQIC              GP + H        GP+
Sbjct: 1  MKFGMGSAQACPCQVPRAASTTWVPCQICETRGAAAAPPLTLEGPVQSHHGTPALTQGPQ 60

Query: 39 TP--GGQLPGARRGPGPRRPAPLPARPPGALGS 69
          +P  G QL    R    R     P  PP  L S
Sbjct: 61 SPRDGAQLGACTRPVDVRDSGGRPLPPPDTLAS 93


>gi|187829742 BCL2 binding component 3 isoform 2 [Homo sapiens]
          Length = 131

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 42/64 (65%), Positives = 46/64 (71%), Gaps = 8/64 (12%)

Query: 1  MKFGMGSAQACPCQVPRAASTTWVPCQICGPR------ERHGPRTPGGQLPGARRGPGPR 54
          MKFGMGSAQACPCQVPRAASTTWVPCQICGP+      E+H   +P    PGA  G GP 
Sbjct: 1  MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQH-LESPVPSAPGALAG-GPT 58

Query: 55 RPAP 58
          + AP
Sbjct: 59 QAAP 62


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 69/250 (27%), Positives = 89/250 (35%), Gaps = 47/250 (18%)

Query: 37  PRTPGG--QLPGARRGPGPRRPAPLPARPPGALGSV-LRPLRARPGCRPRRPHPAARCLP 93
           PR+P G  Q P  + G  P+ P P P +P G       RP    P  +P+ P P      
Sbjct: 90  PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD--- 146

Query: 94  LRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAP------GVARAQRPG 147
            +   P     +P G P   G+    P P PG+       GG  P      G  +   P 
Sbjct: 147 -KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205

Query: 148 GSGGRSHPGGPGSPRG----GGTVGPG-------DRGPAAADGGRPQRTVRAAETRG--- 193
           G   RS    PG P+G    GG    G        +GP    G +PQ      + +G   
Sbjct: 206 GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPA 265

Query: 194 -------AAAAPPLTLEGPVQSHHGTP--------ALTQGPQSPRDGAQLGACTRPVDVR 238
                  +A +PP   +GP Q     P           Q PQ+P  G   G    P    
Sbjct: 266 QGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP---- 321

Query: 239 DSGGRPLPPP 248
             GGRP  PP
Sbjct: 322 -QGGRPSRPP 330



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 56/219 (25%), Positives = 74/219 (33%), Gaps = 24/219 (10%)

Query: 43  QLPGARRGPGPRRPAPLPARPPG-ALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTR 101
           Q P  + G  P+ P P P +P G       +P    P  +P+ P P       +   P  
Sbjct: 37  QGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD----KSRSPRS 92

Query: 102 RHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGG------AAPGVARAQRPGGSGGRSHP 155
              +P G P   G+    P P PG+       GG        PG  +   P G   RS  
Sbjct: 93  PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPR 152

Query: 156 GGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGP------VQSH 209
             PG P+G    G           G+PQ        +     PP   +GP       +S 
Sbjct: 153 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS 212

Query: 210 HGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPP 248
              P   QGP  P+ G Q      P       G+P  PP
Sbjct: 213 QSPPGKPQGP-PPQGGNQ------PQGPPPPPGKPQGPP 244



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 37/144 (25%), Positives = 53/144 (36%), Gaps = 7/144 (4%)

Query: 82  PRRPHPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAGGAAPG 139
           P+ P P     P  P  P  + + P   G     G P P     P      + +  + PG
Sbjct: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95

Query: 140 VARAQRP-GGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAP 198
             +   P GG+  +  P  PG P+G    G G+R       G+PQ      +   +  +P
Sbjct: 96  KPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-GNRPQGPPPPGKPQGPPPQGDKSRSPRSP 154

Query: 199 PLTLEGPVQSHHGTPALTQGPQSP 222
           P   +GP       P   QGP  P
Sbjct: 155 PGKPQGPPPQGGNQP---QGPPPP 175



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 40/129 (31%), Positives = 53/129 (41%), Gaps = 11/129 (8%)

Query: 6   GSAQACPCQVPRAASTTWVPCQICGP-----RERHGPRTPGG--QLPGARRGPGPRRPAP 58
           G  Q  P Q  ++ S+   P +  GP      +  GP  P G  Q P  + G  P+ P P
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 256

Query: 59  --LPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSP 116
              P  PP   GS  +  R+ PG +P+ P       P  P  P   + +    P A G P
Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPG-KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA-GQP 314

Query: 117 QPAPRPAPG 125
           Q  PRP  G
Sbjct: 315 QGPPRPPQG 323


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 77/261 (29%), Positives = 95/261 (36%), Gaps = 47/261 (18%)

Query: 13  CQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGP-GPRRPAPLPARPPGALGSVL 71
           CQ  +  +    P    GPR   GP  P G+      GP GP  P P P  PPG  G+  
Sbjct: 22  CQSLQEETVRKGPAGDRGPRGERGPPGPPGR--DGEDGPTGPPGP-PGPPGPPGLGGNFA 78

Query: 72  RPLRAR-----PG----CRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRP 122
                +     PG      PR P  AA                  G P   G   PA  P
Sbjct: 79  AQYDGKGVGLGPGPMGLMGPRGPPGAA------------------GAPGPQGFQGPAGEP 120

Query: 123 A-PGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGG 180
             PG++      G A P       PG +G   HPG PG P   G VGP G RG     G 
Sbjct: 121 GEPGQTGPAGARGPAGP-------PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGL 173

Query: 181 RPQRTVRAAE----TRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVD 236
              + +R        +G   AP +  E      +GTP  T     P +  ++GA   P  
Sbjct: 174 PGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGA-PGPAG 232

Query: 237 VRDSGGR--PLPPPDTLASAG 255
            R S G   P+ P   + SAG
Sbjct: 233 ARGSDGSVGPVGPAGPIGSAG 253



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 67/237 (28%), Positives = 77/237 (32%), Gaps = 28/237 (11%)

Query: 30  GPRERHGP-RTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPA 88
           G R  HG    PG   P   RGP     A  P  P G+ G    P    P      P   
Sbjct: 571 GERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPP---GPDGNKGEPGVV 627

Query: 89  ARCLPLRPHRPTRR--HRRPGGFPLAWGSP-QPAPRPA---PGRSSALALAGGA-APGVA 141
                  P  P+     R   G P   G   +P  R     PGR  A    G   APG A
Sbjct: 628 GAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA 687

Query: 142 RAQRPGGSGGRSHPGGPGSPRGG----GTVGP-------GDRGPAAADGGRPQRTVRAAE 190
            A    G  G + P GP  PRG     G VGP       G  G A   G + +R  +  +
Sbjct: 688 GATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPK 747

Query: 191 TRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPP 247
                  P     GPV +    PA   GP  P      G          + GR  PP
Sbjct: 748 GENGVVGP----TGPVGA--AGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPP 798



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 62/196 (31%), Positives = 71/196 (36%), Gaps = 48/196 (24%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRR---PAPLPARP-----PGALGSVLRPLRA----- 76
           GP    GPR P    PGA   PGP+    PA  P  P      GA G    P +A     
Sbjct: 91  GPMGLMGPRGP----PGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGH 146

Query: 77  -----RPGCRPRRPHPAARCLPLRPHRP----TRRHRRPGGFPLAWGSP-------QPAP 120
                RPG R       AR  P  P  P     R H    G     G+P        P  
Sbjct: 147 PGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGE 206

Query: 121 RPAPGRSSALALAGG----AAPGVARAQRPGGS----------GGRSHPGGPGSPRGGGT 166
              PG++ A  L G      APG A A+   GS          G    PG PG+P   G 
Sbjct: 207 NGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGE 266

Query: 167 VGP-GDRGPAAADGGR 181
           +G  G+ GPA   G R
Sbjct: 267 IGAVGNAGPAGPAGPR 282



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 63/207 (30%), Positives = 76/207 (36%), Gaps = 22/207 (10%)

Query: 30   GPRERHGPRTPGGQL-----PG--ARRGPGPRRPAPLPARPPGALGSVLRP-LRARPGCR 81
            GPR   GP    G++     PG    +GP        P   PG  G +  P +   PG R
Sbjct: 820  GPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSR 879

Query: 82   PRRPHPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAGGAAPG 139
              R  P        P  P      PG  G P A GSP      APG +      G   P 
Sbjct: 880  GERGLPGVAGAVGEPG-PLGIAGPPGARGPPGAVGSP--GVNGAPGEAGRDGNPGNDGPP 936

Query: 140  VARAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGGRPQRTVRAAETRGAAAAP 198
              R  +PG  G R +PG  G     G  GP G  GPA   G R + T  +     A A  
Sbjct: 937  -GRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGE-TGPSGPVGPAGAVG 994

Query: 199  PLTLEGP--VQSHHGTPALTQGPQSPR 223
            P    GP  ++   G P    G + PR
Sbjct: 995  PRGPSGPQGIRGDKGEP----GEKGPR 1017



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 75/255 (29%), Positives = 86/255 (33%), Gaps = 70/255 (27%)

Query: 25  PCQICGPRERHG----PRTPGGQLPGARRG-PGPRRPAPL--PARPPGALGSVLRPLR-A 76
           P  + GPR   G    P   G Q P    G PG   PA    PA PPG  G    P +  
Sbjct: 92  PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPG 151

Query: 77  RPGCRPRRPHPAARCLPLRPHRP----TRRHRRPGGFPLAWGSP-------QPAPRPAPG 125
           RPG R       AR  P  P  P     R H    G     G+P        P     PG
Sbjct: 152 RPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPG 211

Query: 126 RSSALALAGG----AAPGVARAQR----------------------PGGSG--------G 151
           ++ A  L G      APG A A+                       PG  G        G
Sbjct: 212 QTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271

Query: 152 RSHPGGPGSPRG-------GGTVG-PGDRGPAAADGGRPQRTVRAAETRGAAAAP----P 199
            + P GP  PRG        G VG PG+ G     G +      AA   G A AP    P
Sbjct: 272 NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAK-----GAAGLPGVAGAPGLPGP 326

Query: 200 LTLEGPVQSHHGTPA 214
             + GPV +   T A
Sbjct: 327 RGIPGPVGAAGATGA 341



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 59/195 (30%), Positives = 65/195 (33%), Gaps = 28/195 (14%)

Query: 36  GPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRR--PHPAARCLP 93
           GP  P G  PG R   GP  P    A P GA G        +PG +  R    P      
Sbjct: 703 GPAGPRGS-PGERGEVGPAGPNGF-AGPAGAAG--------QPGAKGERGAKGPKGENGV 752

Query: 94  LRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRS 153
           + P  P       G        P   P PA  R           PG A    P G  G S
Sbjct: 753 VGPTGPVGAAGPAG--------PNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS 804

Query: 154 HPGGPGSPRG-GGTVGP-GDRGPAAADG-----GRPQRTVRAAETRGAAAAPPLTLEGPV 206
            P GP  P G  G  GP GD+GP    G     G P        +  A  A P    GP 
Sbjct: 805 GPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGP- 863

Query: 207 QSHHGTPALTQGPQS 221
           Q   G P +   P S
Sbjct: 864 QGLLGAPGILGLPGS 878



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 72/254 (28%), Positives = 86/254 (33%), Gaps = 82/254 (32%)

Query: 37   PRTPGGQ----------LPGAR--RG----------PGPRRPAPLPAR--PPGALGSVLR 72
            P TPG Q          LPG+R  RG          PGP   A  P    PPGA+GS   
Sbjct: 858  PGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSP-- 915

Query: 73   PLRARPGCRPRRPHPAARCLPLRPHRPTRRHRR--PGGF-PL-AWGSPQP---------- 118
             +   PG   R  +P     P R  +P  +  R  PG   P+ A G+P P          
Sbjct: 916  GVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKH 975

Query: 119  ------APRPAPGRSSALALAGGAAPGVARAQR--PGGSGGRS----------------- 153
                   P    G + A+   G + P   R  +  PG  G R                  
Sbjct: 976  GNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIA 1035

Query: 154  -HPGGPGSPRGGGTVGP----GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQS 208
             H G  G+P   G  GP    G  GPA  DG           T       P  + GP Q 
Sbjct: 1036 GHHGDQGAPGSVGPAGPRGPAGPSGPAGKDG----------RTGHPGTVGPAGIRGP-QG 1084

Query: 209  HHGTPALTQGPQSP 222
            H G PA   GP  P
Sbjct: 1085 HQG-PAGPPGPPGP 1097



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 55/197 (27%), Positives = 63/197 (31%), Gaps = 54/197 (27%)

Query: 44  LPGARRGPGPRRPAPLPARPPGALGSV-LRPLRARPGCRPRRPHPAARCLPLRPHRPTRR 102
           LPG    PG   P  +P  P GA G+   R L   PG    +     +  P         
Sbjct: 314 LPGVAGAPGLPGPRGIPG-PVGAAGATGARGLVGEPGPAGSKGESGNKGEP--------- 363

Query: 103 HRRPGGFPLAWGSPQPAPRPAP----GRSSALALAGGAAPGVARAQRPGGSGGRSHPGGP 158
                      GS  P   P P    G+      AG A P       PG  G R  PG  
Sbjct: 364 -----------GSAGPQGPPGPSGEEGKRGPNGEAGSAGP-------PGPPGLRGSPGSR 405

Query: 159 GSPRGGGTVG----PGDRGPAA--------ADGGRPQRTVRAAETRGAAAAP----PLTL 202
           G P   G  G    PG RG +          D GRP         RG   +P    P   
Sbjct: 406 GLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEP-GLMGPRGLPGSPGNIGPAGK 464

Query: 203 EGPVQSHHGTPALTQGP 219
           EGPV    G P +   P
Sbjct: 465 EGPV----GLPGIDGRP 477



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 50/165 (30%), Positives = 54/165 (32%), Gaps = 29/165 (17%)

Query: 44  LPGARRGPGPRRPA-----------PLPARPPGALGSVLRPLRARPGCRPR------RPH 86
           LPG R  PGP   A           P PA   G  G+   P  A P   P       +  
Sbjct: 323 LPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG 382

Query: 87  PAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPG--VARAQ 144
           P        P  P      PG   L     +      PG   A   AG   P     R  
Sbjct: 383 PNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPG 442

Query: 145 RPGGSGGRSHPGGPGS--PRG-GGTVG-------PGDRGPAAADG 179
            PG  G R  PG PG+  P G  G VG       PG  GPA A G
Sbjct: 443 EPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARG 487



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 65/231 (28%), Positives = 79/231 (34%), Gaps = 35/231 (15%)

Query: 31  PRERHGPRTPGGQ-LPGARRGPGPRRPAPL--------PARPPGALGSVLRPLRARPGCR 81
           P E   P   G + LPG R   G   PA          P  P G +GS      A P   
Sbjct: 204 PGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGS------AGPPGF 257

Query: 82  PRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAA-PGV 140
           P  P P      +    P       G   L   S    P   PG +      G A  PGV
Sbjct: 258 PGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGV 317

Query: 141 ARAQRPGGSGGRSHPGGPGSPRGGGTVG-PGDRGPAAADGGRPQRTVRAAETRGAAAAPP 199
           A A  PG  G R  PG  G+    G  G  G+ GPA + G    +          +A P 
Sbjct: 318 AGA--PGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK------GEPGSAGP- 368

Query: 200 LTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDS-GGRPLPPPD 249
              +GP       P+  +G + P   A       P  +R S G R LP  D
Sbjct: 369 ---QGP-----PGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGAD 411



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 62/228 (27%), Positives = 73/228 (32%), Gaps = 48/228 (21%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPAR--PPGALGSVLRP-LRARPGCRPRRPH 86
           GP    GP    G+ PG     GPR     P    P G  G V  P +  RPG       
Sbjct: 427 GPAGVRGPNGDAGR-PGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPG------- 478

Query: 87  PAARCLPLRPHRPTRRHRRPG--GFPLAWG-SPQPAPRPAPGRSSALALAGGAAP-GVAR 142
                    P  P      PG  GFP   G +  P      G +      G   P G   
Sbjct: 479 ---------PIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNG 529

Query: 143 AQRPGG----SGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAP 198
           AQ P G     GG+   G PG P   G   PG  GPA   G   +R +      G    P
Sbjct: 530 AQGPPGPQGVQGGKGEQGPPGPPGFQGL--PGPSGPAGEVGKPGERGL-----HGEFGLP 582

Query: 199 PLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLP 246
                         PA  +G + P   +     T P+  R   G P P
Sbjct: 583 -------------GPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGP 617



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 50/179 (27%), Positives = 57/179 (31%), Gaps = 19/179 (10%)

Query: 30   GPRERHGPRTPGGQLPGARRGP----GPRRPAPLPARPPGALGSVLRPLRARP-GCRPRR 84
            GP  +HG R   G  P    GP    GPR P+     P G  G    P    P G    +
Sbjct: 970  GPAGKHGNRGETG--PSGPVGPAGAVGPRGPSG----PQGIRGDKGEPGEKGPRGLPGLK 1023

Query: 85   PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQ 144
             H   + LP         H    G P   GS  PA    P   S  A   G         
Sbjct: 1024 GHNGLQGLP-----GIAGHHGDQGAP---GSVGPAGPRGPAGPSGPAGKDGRTGHPGTVG 1075

Query: 145  RPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLE 203
              G  G + H G  G P   G  GP        D G      RA + R A +  P   E
Sbjct: 1076 PAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYE 1134


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 75/239 (31%), Positives = 89/239 (37%), Gaps = 41/239 (17%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPR---RPAPLPARPPGALGSVLRPLRARPGCRPRRPH 86
            G      PRT   Q P    GP P    RP+  P+R PG   +   P+ A+P     +  
Sbjct: 1078 GTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKD 1137

Query: 87   PAARCLPLR--PHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVAR-- 142
            PA    P R  P RP     RP   P     P  A  PAP R     +    +PGVAR  
Sbjct: 1138 PAQPLEPKRPPPPRPVAPPTRPAP-PQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARRE 1196

Query: 143  AQRPGGSG-------GRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAA 195
             + P   G       GRS P    SP+  G  GP   GPA     RP    RA    G  
Sbjct: 1197 MEAPKSPGTTRKDNIGRSQP----SPQ-AGLAGP---GPAGYSTARPTIPPRA----GVI 1244

Query: 196  AAPPLTLEGPVQSHHGTPA--LTQGPQSPRDGAQLGACTRPVDVRDSGGRP----LPPP 248
            +AP        QSH    A  LT   QS       G+   P  ++     P    LPPP
Sbjct: 1245 SAP--------QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPP 1295


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 75/239 (31%), Positives = 89/239 (37%), Gaps = 41/239 (17%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPR---RPAPLPARPPGALGSVLRPLRARPGCRPRRPH 86
            G      PRT   Q P    GP P    RP+  P+R PG   +   P+ A+P     +  
Sbjct: 1078 GTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKD 1137

Query: 87   PAARCLPLR--PHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVAR-- 142
            PA    P R  P RP     RP   P     P  A  PAP R     +    +PGVAR  
Sbjct: 1138 PAQPLEPKRPPPPRPVAPPTRPAP-PQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARRE 1196

Query: 143  AQRPGGSG-------GRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAA 195
             + P   G       GRS P    SP+  G  GP   GPA     RP    RA    G  
Sbjct: 1197 MEAPKSPGTTRKDNIGRSQP----SPQ-AGLAGP---GPAGYSTARPTIPPRA----GVI 1244

Query: 196  AAPPLTLEGPVQSHHGTPA--LTQGPQSPRDGAQLGACTRPVDVRDSGGRP----LPPP 248
            +AP        QSH    A  LT   QS       G+   P  ++     P    LPPP
Sbjct: 1245 SAP--------QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPP 1295


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 69/218 (31%), Positives = 79/218 (36%), Gaps = 21/218 (9%)

Query: 16  PRAASTTWVPCQICGPRERHGPRTPGGQ--LPGARRGPGPRRPAPLPARPPGALGSVLRP 73
           P+  +    P  + G R   GP    G+  +PG R  PG   P P P  P G  G   RP
Sbjct: 377 PKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGP-PGPTGPKGEPGFTGRP 435

Query: 74  LRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQP-APRPAPGRSSALAL 132
               PG            LP +P       R P G P   G   P  P+  PG      L
Sbjct: 436 --GGPGVAGALGQKGDLGLPGQPGL-----RGPSGIPGLQGPAGPIGPQGLPGLKGEPGL 488

Query: 133 AGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVG-PGDRGPAAADGGRPQRTVRAAE- 190
            G   PG  RA  PG +G    PG PGSP   G  G PG  GP  A G   +  +     
Sbjct: 489 PG--PPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHL 546

Query: 191 TRGAAAAPPLTLEGPVQ------SHHGTPALTQGPQSP 222
             G      L   G  Q      S H TPA T    SP
Sbjct: 547 PNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSP 584



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 64/194 (32%), Positives = 74/194 (38%), Gaps = 26/194 (13%)

Query: 45  PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHR 104
           PG    PGPR P      PPG  G   +P   +PG   + P PA       P        
Sbjct: 79  PGPPGKPGPRGPPG----PPGFPG---KPGMGKPGLHGQ-PGPAGP-----PGFSRMGKA 125

Query: 105 RPGGFPLAWGSP-QPAPRPAPGRSSALALAGGAAP-------GVARAQRPGGSGGRSHPG 156
            P G P   G P QP  R  PG      L G   P       G+    +PG  G    PG
Sbjct: 126 GPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPG 185

Query: 157 GPGSPRGGGTVG-PGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPAL 215
             G P   G  G PGDRG    D G  Q  +  A  +G A  PP  L GP  +  G P L
Sbjct: 186 FQGEPGPQGEPGPPGDRG-LKGDNGVGQPGLPGAPGQGGAPGPP-GLPGP--AGLGKPGL 241

Query: 216 TQGPQSPRDGAQLG 229
              P +P D  + G
Sbjct: 242 DGLPGAPGDKGESG 255



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 71/230 (30%), Positives = 79/230 (34%), Gaps = 49/230 (21%)

Query: 30  GPRERHGPR----TPGGQLPGARRGPGPRRPAPLP----ARPPGALGSVLRP----LRAR 77
           GPR   GP      PG   PG    PGP  P        A PPG  G V  P    LR  
Sbjct: 86  GPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGE 145

Query: 78  PGCR-----------PRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGR 126
           PG R           P  P P+   +P +P    +    P GF    G P P   P P  
Sbjct: 146 PGIRGDQGLRGPPGPPGLPGPSGITIPGKPG--AQGVPGPPGFQ---GEPGPQGEPGPPG 200

Query: 127 SSAL-------------ALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVG----P 169
              L             A   G APG      P G G     G PG+P   G  G    P
Sbjct: 201 DRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVP 260

Query: 170 GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGP 219
           G RG   A G +    V      GAA  P    +GP     G P  T+GP
Sbjct: 261 GPRGEPGAVGPKGPPGVDGVGVPGAAGLP--GPQGP-SGAKGEPG-TRGP 306



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 70/226 (30%), Positives = 80/226 (35%), Gaps = 36/226 (15%)

Query: 25  PCQICGPRERHG-------PRTPGGQLPGARRGPGPRRPA-----PLPARPPGALGSVLR 72
           P  + GPR   G       P   G  +PGA   PGP+ P+     P    PPG +G    
Sbjct: 256 PPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY 315

Query: 73  PLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPG-GFPLAWGSPQPAPRPA--PGRSSA 129
            +   PG +  R  PA     L           PG   P   G P   P  A  PGR   
Sbjct: 316 GMPGLPGPKGDR-GPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGP 374

Query: 130 LALAGGA-------APGVARAQRPGGSGGRSHPGGPGSPRGGGTVG-PGDRGPAAADG-- 179
               G A        PG+   Q P G  G+  PG PG     G  G PG  GP    G  
Sbjct: 375 PGPKGEAGPGGPPGVPGIRGDQGPSGLAGK--PGVPGERGLPGAHGPPGPTGPKGEPGFT 432

Query: 180 GRP--QRTVRAAETRGAAAAPPLT-LEGPVQSHHGTPALTQGPQSP 222
           GRP       A   +G    P    L GP     G P L QGP  P
Sbjct: 433 GRPGGPGVAGALGQKGDLGLPGQPGLRGP----SGIPGL-QGPAGP 473



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 54/192 (28%), Positives = 62/192 (32%), Gaps = 25/192 (13%)

Query: 36  GPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLR 95
           GPR   G   G   G      AP+    P   G V  P R   G     P      LPL 
Sbjct: 23  GPRASSGGGAGGAAGY-----APVKYIQPMQKGPVGPPFREGKGQYLEMP------LPLL 71

Query: 96  PHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHP 155
           P         PG         +P PR  PG        G   PG+     P G  G S  
Sbjct: 72  PMDLKGEPGPPG---------KPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRM 122

Query: 156 GGPGSPRGGGTVG-PGDRGPAAADGGRPQRTVRAAETRGAAAAPP-LTLEGP--VQSHHG 211
           G  G P   G VG PG  G     G R  + +R          P  +T+ G    Q   G
Sbjct: 123 GKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPG 182

Query: 212 TPALTQGPQSPR 223
            P   QG   P+
Sbjct: 183 PPGF-QGEPGPQ 193



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 61/225 (27%), Positives = 69/225 (30%), Gaps = 49/225 (21%)

Query: 37  PRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRP 96
           P  PG    G   GP P  P P     PG  G    P        P  P P      + P
Sbjct: 213 PGLPGAPGQGGAPGP-PGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGP 271

Query: 97  HRPTRRHRRPG----GFPLAWGSP----------QPAPRPAPGRSSALALAGGAAPGVAR 142
             P      PG    G P A G P          +P  R  PG            PG   
Sbjct: 272 KGP------PGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKG 325

Query: 143 AQRPGGS----GGRSHPGGPGSPRGGGTVG-------------PGDRGP-----AAADGG 180
            + P G     G R  PG  G P   G  G             PG RGP      A  GG
Sbjct: 326 DRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385

Query: 181 RP-QRTVRAAE-TRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPR 223
            P    +R  +   G A  P +  E  +   HG P    GP  P+
Sbjct: 386 PPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP----GPTGPK 426


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 71/245 (28%), Positives = 85/245 (34%), Gaps = 35/245 (14%)

Query: 36   GPRTPGGQLPGARRGPGPRRP--APLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLP 93
            GP+   GQ PG +  PG + P  AP P    G  G+  R L   PG    R  P      
Sbjct: 921  GPKGDAGQ-PGEKGSPGAQGPPGAPGPLGIAGITGA--RGLAGPPGMPGPRGSPG----- 972

Query: 94   LRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAG-----GAAPGVARAQRPGG 148
              P        +PG   L+     P P+  PG +      G     G+     R   PGG
Sbjct: 973  --PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030

Query: 149  SGGRSH------PGGPGSPRGGGTVGP----GDR------GPAAADGGRPQRTVRAAE-T 191
             G R        PG PG P   G VGP    GDR      GPA A G    R     +  
Sbjct: 1031 KGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090

Query: 192  RGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGG-RPLPPPDT 250
            RG            ++ H G P     P SP    Q GA   P      G   P  PP  
Sbjct: 1091 RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGK 1150

Query: 251  LASAG 255
              ++G
Sbjct: 1151 DGTSG 1155



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 52/162 (32%), Positives = 55/162 (33%), Gaps = 22/162 (13%)

Query: 30   GPRERHGPRTPGGQL-PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPA 88
            GP  + G R   G   P    GP   R AP P  P G  G      R   G +  R  P 
Sbjct: 1056 GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGE--RGAAGIKGHRGFPG 1113

Query: 89   ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPA-------PRPAPGRSSALALAGGAAPGVA 141
                P  P         P G   A GSP PA       P   PG+       G   P   
Sbjct: 1114 NPGAPGSPG--------PAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGP 1165

Query: 142  RAQRP--GGSGGRSHPGGPGSPRGGGTVGP--GDRGPAAADG 179
            R  R   G  G   HPG PG P   G  GP  G  G AA  G
Sbjct: 1166 RGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAG 1207



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 80/267 (29%), Positives = 93/267 (34%), Gaps = 51/267 (19%)

Query: 13  CQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPG-PRRP-APLPARPPGALGSV 70
           C  P  A T   P    GP+   G   P G +PG    PG P +P +P    PPG   S 
Sbjct: 88  CPQPPTAPTR--PPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPGSPGSPGPPGICESC 144

Query: 71  -LRPLRARP-------------GCRPRRPHPAARCLPLRPHRPTRRHRRPG--GFPLAWG 114
              P    P             G     P PA    P  P  P      PG  G P   G
Sbjct: 145 PTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAG---PPGPPGPPGTSGHPGSPGSPGYQG 201

Query: 115 SP----QPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVG-P 169
            P    Q  P   PG   A+  +G A      + RPG  G R  PG PG     G  G P
Sbjct: 202 PPGEPGQAGPSGPPGPPGAIGPSGPAGKD-GESGRPGRPGERGLPGPPGIKGPAGIPGFP 260

Query: 170 GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSP------- 222
           G +G    DG   +        +G   AP L  E  +   +G P    GP  P       
Sbjct: 261 GMKGHRGFDGRNGE--------KGETGAPGLKGENGLPGENGAP----GPMGPRGAPGER 308

Query: 223 -RDGAQLGACTRPVD-VRDSGGRPLPP 247
            R G    A  R  D  R S G+P PP
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQPGPP 335



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 57/170 (33%), Positives = 64/170 (37%), Gaps = 34/170 (20%)

Query: 33   ERHGPRTPGGQLPGARRGPGPRRPAPL--------PARPPGALGSVLRPLRARPGCRPRR 84
            E   P  PG   PG    PGP  PA          PA P GA G    P  +R    P+ 
Sbjct: 1036 ENGSPGAPGA--PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG----PAGSRGAPGPQG 1089

Query: 85   PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPG--VAR 142
            P         R     + HR   G P A GSP PA     G+  A+   G A P   V  
Sbjct: 1090 PRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPA-----GQQGAIGSPGPAGPRGPVGP 1144

Query: 143  AQRPGGSGGRSHPG--GPGSPRGG----GTVG-------PGDRGPAAADG 179
            +  PG  G   HPG  GP  PRG     G+ G       PG  GP  A G
Sbjct: 1145 SGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 83/280 (29%), Positives = 97/280 (34%), Gaps = 63/280 (22%)

Query: 31  PRERHGPRTPGGQLPGARRGPGPRRP-----APLPARPPGALGSVLRPLRARPGCR---- 81
           P ER  P   G   PG R G GP  P     A  P  PPGA G+    L+  PG R    
Sbjct: 680 PGERGPPGLAGA--PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTP--GLQGMPGERGGLG 735

Query: 82  -------------------PRRPHPAARCLPLRPHRPTRR--HRRPGGFPLAWGSPQPA- 119
                              P +  P     P+ P  P  +   +  GG P   G P  A 
Sbjct: 736 SPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAP---GLPGIAG 792

Query: 120 PRPAPGRSSALALAGGAA-PGV-ARAQRPGGSGGRSHPG-----GP----GSPRGGGTVG 168
           PR +PG        G A  PG   +   PGG G R  PG     GP    G P G G  G
Sbjct: 793 PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG 852

Query: 169 P-------GDRGPAAADG--GRP-QRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQG 218
           P       G+RG     G  G P  R +           PP     P +     PA   G
Sbjct: 853 PPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG 912

Query: 219 -PQSPRDGAQLGACTRPVDVRDSGGRPLPP--PDTLASAG 255
            P SP      G   +P + + S G   PP  P  L  AG
Sbjct: 913 APGSPGVSGPKGDAGQPGE-KGSPGAQGPPGAPGPLGIAG 951



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 68/215 (31%), Positives = 75/215 (34%), Gaps = 29/215 (13%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP--PGALGSVLRP-LRARPGCRPRRPH 86
           G R   G R   GQ PG    PGP   A  P  P   G +G    P     PG R   P 
Sbjct: 318 GARGNDGARGSDGQ-PGP---PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE-PG 372

Query: 87  PAARCLPLRPHRPTRRHRRPGG--------FPLAWGSPQPAPRPAP-GRSSALALAGGAA 137
           P        P  P   +  PGG         P A G       P P G + A  L GGA 
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432

Query: 138 -PGVARAQ-RPGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAAADGGRPQRTVRAAET 191
            PG   A+  PG  G R   G PG P   G  G    PG+ G     G   +R   A   
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGER--GAPGF 490

Query: 192 RGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGA 226
           RG A    +  E       G P    GP  PR  A
Sbjct: 491 RGPAGPNGIPGEKGPAGERGAP----GPAGPRGAA 521



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 61/211 (28%), Positives = 72/211 (34%), Gaps = 34/211 (16%)

Query: 30   GPRERHGPRTPG-GQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPA 88
            G  ER  P   G G  PG    PG   PA     PPG  G  ++  R  PG       P 
Sbjct: 823  GKGERGAPGEKGEGGPPGVAGPPGGSGPAG----PPGPQG--VKGERGSPGGPGAAGFPG 876

Query: 89   ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGG 148
            AR LP     P   +  PG  P   GSP     P P  ++    + G +     A +PG 
Sbjct: 877  ARGLP----GPPGSNGNPGP-PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGE 931

Query: 149  SGGRSHPGGPGSPRGGGTVG-------------PGDRGPAAADGGRPQRTVRAAETRGAA 195
             G     G PG+P   G  G             PG RG     G + +     A      
Sbjct: 932  KGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE 991

Query: 196  AAPPLTLEGPVQSHHGTPALTQGPQSP-RDG 225
              PP    GP     G P L      P RDG
Sbjct: 992  RGPP----GP----QGLPGLAGTAGEPGRDG 1014



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 57/164 (34%), Positives = 60/164 (36%), Gaps = 25/164 (15%)

Query: 31  PRERHGPRTPGGQLPGARRGPGPRRPAPLPARP--PGALGSVLRPLRARPGCRPRRPHPA 88
           P  R G   PG    GA+  PGPR        P  PGA G   +     PG       P 
Sbjct: 425 PGLRGGAGEPGKN--GAKGEPGPRGERGEAGIPGVPGAKGEDGKD--GSPG------EPG 474

Query: 89  ARCLP-LRPHRPTRRHRRPGGFPLAWGSPQPA-PRPAPGRSSALALAGGAAPGVARAQRP 146
           A  LP     R     R P G     G   PA  R APG +     AG   PG  R   P
Sbjct: 475 ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG--EPG--RDGVP 530

Query: 147 GGSGGRSHPGGPGSPRGGGTVGP-------GDRGPAAADGGRPQ 183
           GG G R  PG PG P   G  GP       G  GP    G R Q
Sbjct: 531 GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQ 574



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 56/184 (30%), Positives = 68/184 (36%), Gaps = 43/184 (23%)

Query: 30   GPRERHGPRTPGGQL--PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHP 87
            GPR   GP+   G+   PGA    G R P P P   PG  G+        PG   R  +P
Sbjct: 966  GPRGSPGPQGVKGESGKPGANGLSGERGP-PGPQGLPGLAGTA-----GEPG---RDGNP 1016

Query: 88   AARCLPLRPHRPTRR-HRRPGGFPLAWGSPQPAPRPAP----------GRSSALALAGGA 136
             +  LP R   P  +  R   G P A G+P     P P          G S     AG  
Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAP 1076

Query: 137  APGVARA----QRP----------GGSGGRSHPGGPGSPRGGGTVGP-------GDRGPA 175
             P  +R     Q P          G +G + H G PG+P   G+ GP       G  GPA
Sbjct: 1077 GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPA 1136

Query: 176  AADG 179
               G
Sbjct: 1137 GPRG 1140



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 67/236 (28%), Positives = 83/236 (35%), Gaps = 49/236 (20%)

Query: 30  GPRERHGPRTPGGQ--------LPGARRGPGP---RRPAPLPARPP-----------GAL 67
           GP    GP  P G+         PG R  PGP   + PA +P  P            G  
Sbjct: 216 GPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEK 275

Query: 68  GSVLRP-LRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPG--------GFPLAWGSP-Q 117
           G    P L+   G       P     P+ P        RPG        G   A GS  Q
Sbjct: 276 GETGAPGLKGENGLPGENGAPG----PMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQ 331

Query: 118 PAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVG-PGDRGPAA 176
           P P P P  ++    + GA   V  A  PG +G     G PG     G  G PG  G   
Sbjct: 332 PGP-PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING 390

Query: 177 ADGGR----PQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSP-RDGAQ 227
           + GG+    P     A    GA   P     GP  + +G P L  G   P ++GA+
Sbjct: 391 SPGGKGEMGPAGIPGAPGLMGARGPP-----GPAGA-NGAPGLRGGAGEPGKNGAK 440



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 65/229 (28%), Positives = 76/229 (33%), Gaps = 50/229 (21%)

Query: 33  ERHGPRTPGGQLPGARRGP-GPRRPAPLPARPPGALGSVLRP----LRARPGCRPRRPHP 87
           ER GP  PG Q P  + G  GP+ P P P  P G  G    P    L+  PG        
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGP-PGPTGPGGDKGDTGPPGPQGLQGLPGT------- 646

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSP-QPAPRPAPGRSSALALAGGAAPGVARAQRP 146
                              GG P   G P +P P+   G       A GA  G   A  P
Sbjct: 647 -------------------GGPPGENGKPGEPGPKGDAG-------APGAPGGKGDAGAP 680

Query: 147 GGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG-----GRPQRTVRAAETRGAAAAPPL 200
           G  G     G PG   G G  GP G +G A   G     G P       E  G  +  P 
Sbjct: 681 GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPK 740

Query: 201 TLEGPV--QSHHGTPALTQGPQSPRDG-AQLGACTRPVDVRDSGGRPLP 246
             +G        G P    GP+ P       G   +P D  + G   LP
Sbjct: 741 GDKGEPGGPGADGVPG-KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLP 788


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 65/235 (27%), Positives = 81/235 (34%), Gaps = 38/235 (16%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGP---------RRPAPLPARPPGALGSVLRPLRARPGC 80
           GP  + G +  G   PG  +GP P         R P   P  PP   G+  +     PG 
Sbjct: 203 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPG- 261

Query: 81  RPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGG----- 135
           +P+ P P     P  P  P +    P G P   GS   + R  PG+       GG     
Sbjct: 262 KPQGPPPQGGNKPQGPPPPGK----PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG 317

Query: 136 --AAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRG 193
               PG  +   P G      P  PG P+G    G      A +  G+PQ         G
Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ---------G 368

Query: 194 AAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPP 248
                    +GP     G P   Q PQ+P  G   G    P      GGRP  PP
Sbjct: 369 PPQQEGNNPQGPPPPAGGNP---QQPQAPPAGQPQGPPRPP-----QGGRPSRPP 415



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 66/240 (27%), Positives = 86/240 (35%), Gaps = 36/240 (15%)

Query: 30  GPRERHGPRTPGG--QLPGARRGPGPRRPAPLPARPPG-ALGSVLRPLRARPGCRPRRPH 86
           G  +  GP +P G  Q P  + G  P+ P P P +P G       +P    P  +P+ P 
Sbjct: 43  GGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 102

Query: 87  PAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGG------AAPGV 140
           P       +   P     +P G P   G+    P P PG+       GG        PG 
Sbjct: 103 PQGD----KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 158

Query: 141 ARAQRPGGS----GGRSHPGGP-GSPRGGGTVGPG-------DRGPAAADGGRPQRTVRA 188
            +   P G       RS PG P G P  GG    G        +GP    G +PQ     
Sbjct: 159 PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 218

Query: 189 AETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPP 248
            + +G    PP   +   QS    P   QGP  P+ G Q      P       G+P  PP
Sbjct: 219 GKPQG----PPPQGDNKSQSARSPPGKPQGP-PPQGGNQ------PQGPPPPPGKPQGPP 267



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 58/235 (24%), Positives = 79/235 (33%), Gaps = 22/235 (9%)

Query: 30  GPRERHGPRTPGGQLPGARRGP--------GPRRPAPLPARPPGALGSVLRPLRARPGCR 81
           GP  + G +  G   PG  +GP         PR P   P  PP   G+  +     PG +
Sbjct: 80  GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG-K 138

Query: 82  PRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGG------ 135
           P+ P P     P  P  P +    P G P    +   + R  PG+       GG      
Sbjct: 139 PQGPPPQGGNKPQGPPPPGK----PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194

Query: 136 -AAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQ-RTVRAAETRG 193
              PG  +   P G      P  PG P+G    G      A +  G+PQ    +      
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ 254

Query: 194 AAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPP 248
               PP   +GP       P     P  P+     G  ++    R   G+P  PP
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG-SKSRSSRSPPGKPQGPP 308



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 37/152 (24%), Positives = 46/152 (30%), Gaps = 12/152 (7%)

Query: 106 PGGFPLAWGSPQPAPRPAPGRSSALALAGG-------AAPGVARAQRPGGSGGRSHPGGP 158
           P G P   G+    P   PG+       GG         PG  +   P G      P  P
Sbjct: 36  PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 95

Query: 159 GSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQG 218
           G P+G    G   R P +  G       +          PP   +GP       P   QG
Sbjct: 96  GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP---QG 152

Query: 219 PQSP--RDGAQLGACTRPVDVRDSGGRPLPPP 248
           P  P    G       +    R   G+P  PP
Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP 184


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 71/228 (31%), Positives = 83/228 (36%), Gaps = 35/228 (15%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPR---RPAPLPARPPGALGSVLRPLRARPGCRPRRPH 86
            G      PRT   Q P    GP P    RP+  P+R PG   +   P+ A+P     +  
Sbjct: 1039 GTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKD 1098

Query: 87   PAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRP 146
            PA    P RP  P     RP   P     PQ  P P+  RS A       AP      R 
Sbjct: 1099 PAQPLEPKRPPPP-----RPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRK 1153

Query: 147  GGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPV 206
                GRS P    SP+  G  GP   GPA     RP    RA    G  +AP        
Sbjct: 1154 DNI-GRSQP----SPQ-AGLAGP---GPAGYSTARPTIPPRA----GVISAP-------- 1192

Query: 207  QSHHGTPA--LTQGPQSPRDGAQLGACTRPVDVRDSGGRP----LPPP 248
            QSH    A  LT   QS       G+   P  ++     P    LPPP
Sbjct: 1193 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPP 1240


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 75/262 (28%), Positives = 86/262 (32%), Gaps = 40/262 (15%)

Query: 16   PRAASTTWVPCQI-CGPRERHGPRTPGGQLPGARRGPGPRRP--APLP--ARPPGALGSV 70
            P+ A  T  P  I   P  +  P  P    P  + GP    P  AP P  A PP   G  
Sbjct: 918  PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977

Query: 71   LRP----LRARPGCRPRRPH--PAARCLPLRPHRPTRRHRRPGG------FPLAWGSPQP 118
              P        P   P  P   PA       P  P      P G      FP    +P  
Sbjct: 978  ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037

Query: 119  APRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAAD 178
            A  P+P  S A       AP    A  P   GG + P   G+P       P  +G  A  
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 179  GGRPQRTVRAA---ETRGAAAAPPLTLEGPVQSHHG---TPALTQGPQSPRDGAQL---- 228
              +      AA     +G  A PP         H G   TPA T  P SP+ G       
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPP---------HKGAPTTPAAT--PPSPKGGLATPPPK 1146

Query: 229  GACTRPVDVRDS--GGRPLPPP 248
            GA T P     S  GG   PPP
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPP 1168



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 62/229 (27%), Positives = 76/229 (33%), Gaps = 28/229 (12%)

Query: 52   GPRRPAPLPARPPGALGSVLRPLRARPGCR--PRRPHPAARCLPLRPHRPTRRHRRPGGF 109
            GP  PAP  A       S  +  RA P  +  P  P P        P  P      P G 
Sbjct: 899  GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG-----APTPPAATPPSPKGG 953

Query: 110  PLA----WGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGG 165
            P      W    PA  P   +      +   AP    A  P   GG + P   G+P    
Sbjct: 954  PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013

Query: 166  TVGPGDRG-PAAADGGRPQRTVRAA---ETRGAAAAPPLTLEGPVQSHHGTPALTQGPQS 221
               P  +G PAA    +   T  AA     +G+ AA PL    P       P+   GP +
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073

Query: 222  PRDGAQLGACTRPVDVRDS----------GGRPLPPPDTLASAGDFLCT 260
            P   +  GA T P     S           G P+PP  T  S    L T
Sbjct: 1074 P---SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 79/290 (27%), Positives = 96/290 (33%), Gaps = 52/290 (17%)

Query: 6    GSAQACPCQVPRAASTTWVPCQICGPRERHGPRTP---GGQLPGARRGPGPR-------- 54
            GS  A P  +P+ A TT  P     P  + GP TP   G   P A   P P+        
Sbjct: 1045 GSPAATP--LPKGAPTT--PAATL-PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 55   RPAPLP--ARPPGALGSVLRPLR----ARPGCRPRRPHPAARCLPLR--PHRPTRRHRRP 106
            + AP+P  A PP   G +  P        P   P  P       P +  P  P      P
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159

Query: 107  GG---FPLAWGSPQ-PAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPR 162
             G    P   G+P  PA  P   +      +   AP    A  P   GG + P   G+P 
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219

Query: 163  ---------GGGTVGPGDRG--------PAAADGGRPQRTVRAAETRGAAAAPPLTLEGP 205
                      GG   P  +G        P +  GG      + A T  AA  P L     
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279

Query: 206  VQSHHGTP-ALTQGPQSPRDGAQL----GACTRPVDVRDS--GGRPLPPP 248
               H G P      P SP+ G       GA T P     S  G    PPP
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 58/229 (25%), Positives = 81/229 (35%), Gaps = 27/229 (11%)

Query: 16   PRAASTTWVPCQICGPRERHGPRTP---GGQLPGARRGPGPRRPAPLPARPPGALGSVLR 72
            P+ A T   P     P  +  P TP   G   P A   P P+    LPA  P + G    
Sbjct: 1306 PKGAPT---PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT 1362

Query: 73   PLRARPGCRPRRPHPAARCLP-LRPHRPTRRHR--RPGGFPLAWG----SPQPAPRPAPG 125
            P  ++ G  P    P+ +  P + P  P R      P G P +      SP+ AP     
Sbjct: 1363 P-SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT 1421

Query: 126  RSSALALAGG-----AAPGVARAQRPGGS---GGRSHPGGPGSPRGGGTVGPGDRGPAA- 176
            R  A   + G     A   V+  + P  S   GG + P   G P       P  + P A 
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481

Query: 177  ---ADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSP 222
               A    P++        GA   P +    P +    TP+  + P +P
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIPSSP-KEVPATPSSRRDPIAP 1529



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 65/272 (23%), Positives = 85/272 (31%), Gaps = 43/272 (15%)

Query: 16   PRAASTTWVPCQICGPRERHGPR----TPGGQLPGARRGPGPRRPAPLPARPPGALGSVL 71
            P AA+   +   +  P  +  P     TP     G    P    P P  A PP   GS  
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325

Query: 72   RPLRARPGCRPRRPHPAARCLPLRPHR-------PTRRHRRPGGFPLA-----WGSPQPA 119
             P        P    P+ +  P  P         PT    + G  P A      G P   
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 120  PRPAPGRSSALALAGG--AAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAA- 176
            P P+P R  A+    G   +P V           +  P  P +  G  T   GD  P A 
Sbjct: 1386 P-PSPKRGPAIPSPKGDPTSPAVIPL------SPKKAPATPVTREGAATPSKGDLTPPAV 1438

Query: 177  ------------ADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRD 224
                        A  G P       +    A  PP   E P      T +  +  ++P  
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK--KAPAT 1496

Query: 225  GAQLGACTRPVDVRDSGGRPLPPPDTLASAGD 256
             A +GA T P  +  S   P   P T +S  D
Sbjct: 1497 PAPMGAPTLPAVIPSS---PKEVPATPSSRRD 1525


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 78/248 (31%), Positives = 86/248 (34%), Gaps = 56/248 (22%)

Query: 30   GPRERHGPRTPG--GQLPGARRGPG-PRRPAPL-PARPPGALGSVLRPLRARPGCRPRRP 85
            G R   GP  PG  G  PG    PG P  P P  P  PPG  G         PG      
Sbjct: 1403 GDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPG------ 1456

Query: 86   HPAARCLPLRPHRPTRRHRR--PG--------GFPLAWGSP-QPAPRPAPGRSSALALAG 134
                  LP +P  P  +  R  PG        GFP   G   +   R  PG + +  L G
Sbjct: 1457 ------LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPG 1510

Query: 135  GAA-PGVARAQRPGGSGGRS-HPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETR 192
             A  PG    + P G  GR    G PG P     VGP   GP    G      V  A  R
Sbjct: 1511 VAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG-----DVGPAGPR 1565

Query: 193  GAAAAPPLTLEGPVQSHHGTPALT----QGPQ-SPRDGAQLGACTRPVDVRDSG------ 241
            GA           VQ   G P L      GP+  P D   +G   R     DSG      
Sbjct: 1566 GATG---------VQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616

Query: 242  --GRPLPP 247
              GRP PP
Sbjct: 1617 DPGRPGPP 1624



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 73/246 (29%), Positives = 86/246 (34%), Gaps = 50/246 (20%)

Query: 25   PCQICGPRERHGPRTPGGQ--LPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPG--- 79
            P    G +   GP  P G   LPG    PG + P   P  P G  G    P   RPG   
Sbjct: 1487 PLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPG-PTGRQGEKGEP--GRPGDPA 1543

Query: 80   -CRPRRPHPAARCLPLRPHRP-----TRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALA 133
               P    P      + P  P      +  R P G  L      P P+  PG    + L 
Sbjct: 1544 VVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPG---DPGPKGDPGDRGPIGLT 1600

Query: 134  GGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP----------GDRGPAAADGGRPQ 183
            G A P       PG SG     G PG P   G VGP          GD GP   D G P 
Sbjct: 1601 GRAGP-------PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGP-PGDPGLPG 1652

Query: 184  RTVRAAETRGAAAAPPLTLEGPV--QSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSG 241
            +    A  RG   AP   + GPV  +   G P      +  R+G+     + P   R   
Sbjct: 1653 K----AGERGLRGAP--GVRGPVGEKGDQGDPG-----EDGRNGSP--GSSGPKGDRGEP 1699

Query: 242  GRPLPP 247
            G P PP
Sbjct: 1700 GPPGPP 1705



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 62/199 (31%), Positives = 72/199 (36%), Gaps = 35/199 (17%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP-----PGALGSVLRPLRARPGCRPRR 84
            G R   GP+ P G   G R  PGP   A  P +P     PG  G V      RPG R  R
Sbjct: 2006 GDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGE--AGRPGERGER 2063

Query: 85   PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQ 144
                      +  R  +    P G P   G+P P   P P  S          PG++  Q
Sbjct: 2064 GE--------KGERGEQGRDGPPGLP---GTPGPPGPPGPKVS-----VDEPGPGLSGEQ 2107

Query: 145  RPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLE 203
             P G       G  G P   G  GP GDRG     G R +        RG    P L  E
Sbjct: 2108 GPPGL-----KGAKGEPGSNGDQGPKGDRGVPGIKGDRGE-----PGPRGQDGNPGLPGE 2157

Query: 204  GPVQSHHGTPALTQGPQSP 222
              +    G P L QGP+ P
Sbjct: 2158 RGMAGPEGKPGL-QGPRGP 2175



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 78/274 (28%), Positives = 97/274 (35%), Gaps = 44/274 (16%)

Query: 13   CQVPRAASTTWVPCQICGPRERHGPRTPG-----GQL--PGARRGPGPRRPAPLPARPPG 65
            CQ          PC +  P+ + G   PG     GQ+  PG    PG R  AP P  PPG
Sbjct: 1234 CQASFTTQPRPEPCPVYCPKGQKGE--PGEMGLRGQVGPPGDPGLPG-RTGAPGPQGPPG 1290

Query: 66   ALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSP-QPAPRPAP 124
            +  +  +  R  PG   R   P     P  P  P  +     G P   G P +  PR   
Sbjct: 1291 S--ATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSP--GLPGPRGDPGERGPRGPK 1346

Query: 125  GRSSALA-LAGGAAPGV-ARAQRPGGSGG------------RSHPGGPGSPRGG------ 164
            G   A   + GG  PG+  R   PG SG             R  PG PG+   G      
Sbjct: 1347 GEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRG 1406

Query: 165  --GTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSP 222
              G  GPG+ G A  + G P   +  +        PP        S  G P L   P SP
Sbjct: 1407 ERGPPGPGEGGIAPGEPGLP--GLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSP 1464

Query: 223  RDGAQLGACTRPVDVRDSGGRPLPPPDTLASAGD 256
             +    G    P  +   G R  P P  L  AG+
Sbjct: 1465 GEQGPRGP---PGAIGPKGDRGFPGP--LGEAGE 1493



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 72/248 (29%), Positives = 86/248 (34%), Gaps = 46/248 (18%)

Query: 28   ICGPRERHGPRTPGGQ--LPGARRGPGPRRPAPL--PARPPGALGSVLRPLRARPGCRPR 83
            I G R   GPR   G   LPG R   GP     L  P  PPG +G         PG  P 
Sbjct: 2136 IKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGG-----HGDPG-PPG 2189

Query: 84   RPHPAARCLPLRPHRPTRRHRRPG----------------GFPLAWGSPQPA----PRPA 123
             P  A    P  P  P+     PG                G P   G P P+    P+ +
Sbjct: 2190 APGLAG---PAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP---GPPGPSGLVGPQGS 2243

Query: 124  PGRSSALALAGG-AAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGGR 181
            PG    +   G   APG     R G SG     G PG P   G  GP G +G     G  
Sbjct: 2244 PGLPGQVGETGKPGAPG-----RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP 2298

Query: 182  PQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPR-DGAQLGACTRPVDVRDS 240
             Q  V     +G   AP   L G +    G     +G   PR +  + G    P D  + 
Sbjct: 2299 GQAVVGLPGAKGEKGAPG-GLAGDLVGEPGAKG-DRGLPGPRGEKGEAGRAGEPGDPGED 2356

Query: 241  GGRPLPPP 248
            G +  P P
Sbjct: 2357 GQKGAPGP 2364



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 69/223 (30%), Positives = 80/223 (35%), Gaps = 25/223 (11%)

Query: 15   VPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPL 74
            +P A      P Q  GPR   G   P G+   A  GP  R   P P  PPG  GSV  P 
Sbjct: 2396 LPGAPGVVGFPGQT-GPRGEMGQPGPSGERGLA--GPPGREGIPGPLGPPGPPGSVGPP- 2451

Query: 75   RARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAG 134
                G +  +  P       R  R     R   G P      Q  PR   G   +     
Sbjct: 2452 -GASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRP-----GQEGPRGLTGPPGSRG-ER 2504

Query: 135  GAAPGVARAQRPGGSGGRSHPGGPGSPRGG----GTVGP----GDRGPAAADGGRPQRTV 186
            G    V  A   G  G  +   GP  PRG     G  GP    GD+GP   D G P    
Sbjct: 2505 GEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGP-RGDNGDPGDKG 2563

Query: 187  RAAE--TRGAAAAPPLT-LEGPVQSHHGTPALTQGPQSP-RDG 225
               E   +G+A  P L  L GP Q   G   +   P SP +DG
Sbjct: 2564 SKGEPGDKGSAGLPGLRGLLGP-QGQPGAAGIPGDPGSPGKDG 2605



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 51/165 (30%), Positives = 62/165 (37%), Gaps = 21/165 (12%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLR-ARPGCRPRRPHPA 88
            GP    G R P G L G R G   +  A  P+ P GA G    P R   PG R  +  P 
Sbjct: 1764 GPAGEKGDRGPPG-LDG-RSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG 1821

Query: 89   ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGA------------ 136
                P  P +P     +PG   L   + +P      GR      +G +            
Sbjct: 1822 PSGPPGLPGKPGE-DGKPG---LNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGER 1877

Query: 137  -APGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG 179
             APG+   Q P G  G   P G G P   G  GP GDRG   + G
Sbjct: 1878 GAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKG 1922



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 64/221 (28%), Positives = 72/221 (32%), Gaps = 56/221 (25%)

Query: 30   GPRER---HGPRTPGGQL----PGARRGPGPRRPAPLPAR--PPGALGSVLRPLRARPGC 80
            GPR      G R P G +    PG +  PG R P  L  R  PPG  G         PG 
Sbjct: 1563 GPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGP--------PGE 1614

Query: 81   R--PRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAP 138
            +  P RP P           P     R G          P     PG++    L G  AP
Sbjct: 1615 KGDPGRPGPPG---------PVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRG--AP 1663

Query: 139  GV----------------ARAQRPGGSG---GRSHPGGPGSPRGGGTVGPGDRGPAAADG 179
            GV                 R   PG SG    R  PG PG P      GPG R      G
Sbjct: 1664 GVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR-EKGEPG 1722

Query: 180  GRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQ 220
             R Q   R    +G    P    E  ++   G P    GPQ
Sbjct: 1723 DRGQEGPRG--PKGDPGLPGAPGERGIEGFRGPP----GPQ 1757



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 47/177 (26%), Positives = 57/177 (32%), Gaps = 44/177 (24%)

Query: 106  PGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARA--QRPGGSGGRSHPGGPGSPRG 163
            PG   LA    +      PG+S A    G   P   R    +PG  G +   G  G+P  
Sbjct: 2649 PGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGI 2708

Query: 164  GGTVGP----------------GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQ 207
            GG  GP                G RGP    G + +R        GA   P    E   +
Sbjct: 2709 GGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGE---R 2765

Query: 208  SHHGTPALTQGPQSPRDGAQLGACTRPVDVRD------------------SGGRPLP 246
               G P    GP  PR G +  A     D+R                   SG RPLP
Sbjct: 2766 GEQGRP----GPAGPR-GEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLP 2817



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 64/220 (29%), Positives = 75/220 (34%), Gaps = 15/220 (6%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAA 89
            G   + G R   G +PG+   PGP  P   P  P GA G  +  L   PG +  +  P  
Sbjct: 2263 GASGKDGDRGSPG-VPGSPGLPGPVGPKGEPG-PTGAPGQAVVGL---PGAKGEKGAPGG 2317

Query: 90   RCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA-PGRSSALALAGGAAPGVARAQRPGG 148
                L      +  R   G P   G    A R   PG        G  APG    +   G
Sbjct: 2318 LAGDLVGEPGAKGDR---GLPGPRGEKGEAGRAGEPGDPGEDGQKG--APGPKGFKGDPG 2372

Query: 149  SGGRSHPGGPGSPRGGGTVG-PGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQ 207
             G    PG PG P   G +G PG  G A    G P +T    E      +    L GP  
Sbjct: 2373 VGVPGSPGPPGPPGVKGDLGLPGLPG-APGVVGFPGQTGPRGEMGQPGPSGERGLAGP-P 2430

Query: 208  SHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSG-GRPLP 246
               G P     P  P      GA     D  D G G P P
Sbjct: 2431 GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGP 2470



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 55/198 (27%), Positives = 66/198 (33%), Gaps = 22/198 (11%)

Query: 45   PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPR-RPHPAARCLPLRPHRPTRRH 103
            PG+  GP   R  P P  PPG L      +   PG R +  P    +  P  P       
Sbjct: 1687 PGSS-GPKGDRGEPGPPGPPGRL------VDTGPGAREKGEPGDRGQEGPRGPKGDPGLP 1739

Query: 104  RRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRG 163
              PG   +      P P+  PG      + G A  G    + P G  GRS  G  G P  
Sbjct: 1740 GAPGERGIEGFRGPPGPQGDPG------VRGPA--GEKGDRGPPGLDGRS--GLDGKPGA 1789

Query: 164  GGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPR 223
             G  GP      A D GR        E      + P  L G      G P L      P 
Sbjct: 1790 AGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGK-PGEDGKPGLNGKNGEPG 1848

Query: 224  DGAQLGACTRPVDVRDSG 241
            D  + G   R  +  DSG
Sbjct: 1849 DPGEDG---RKGEKGDSG 1863



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 45/156 (28%), Positives = 54/156 (34%), Gaps = 17/156 (10%)

Query: 30   GPRERHGPRTPGGQ-LPGARRGPGPR--RPAPLPARPPGALGSVLRPLRARPGCRPRRPH 86
            GP    GP  P GQ  PG   G GP+  R         G  G   R LR  PG  P    
Sbjct: 1887 GPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGE--RGLRGEPGSVPN--- 1941

Query: 87   PAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAP---RPAPGRSSALALAGGAAPGVARA 143
               R L     + +        +  + GS  P P   R   G S      G   P     
Sbjct: 1942 -VDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGP----I 1996

Query: 144  QRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADG 179
              PG  G +   G PG P+G   +  G+RGP    G
Sbjct: 1997 GFPGERGLKGDRGDPG-PQGPPGLALGERGPPGPSG 2031


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 65/219 (29%), Positives = 80/219 (36%), Gaps = 29/219 (13%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPR---RPAPLPARPPGALGSVLRPLRARPGCRPRRPH 86
            G      PRT   Q P    GP P    RP+  P+R PG   +   P+ A+P     +  
Sbjct: 1034 GTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKD 1093

Query: 87   PAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRP 146
            PA    P RP  P     RP   P     PQ  P P+ GRS     AG A PG A     
Sbjct: 1094 PAQPLEPKRPPPP-----RPVAPPTRPAPPQRPPPPS-GRSQPSPQAGLAGPGPA----- 1142

Query: 147  GGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAET-----------RGAA 195
            G S  R  P  P  PR G    P     A+A    P+   + +ET           +  A
Sbjct: 1143 GYSTAR--PTIP--PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQA 1198

Query: 196  AAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRP 234
            A PP +   P       P +      P+ G Q    T P
Sbjct: 1199 AFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPP 1237


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 66/209 (31%), Positives = 76/209 (36%), Gaps = 37/209 (17%)

Query: 31  PRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAAR 90
           P    G    G   P +R  P  R P P    PPG  GS        P  RP +    +R
Sbjct: 61  PESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPP--RPSQHQSGSR 118

Query: 91  CLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPG--G 148
              LRP                      AP P PG SSA A    AAP  A    PG   
Sbjct: 119 ---LRP---------------------AAPGPRPGCSSARASPAPAAPQAAARTAPGRAA 154

Query: 149 SGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEG-PVQ 207
           SGG     GPGS RG G+   G R P+ A G  P  T R        +A P    G P++
Sbjct: 155 SGG----SGPGS-RGQGSDQVGAR-PSRAGGQPPPLTCRRCRAAPRRSARPFRRPGLPLK 208

Query: 208 SH--HGTPALTQGPQSPRDGAQLGACTRP 234
           S    GT A + G      G    A + P
Sbjct: 209 SRPGSGTGARSCGTWGSGGGPGTAAASSP 237



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 45/187 (24%), Positives = 52/187 (27%), Gaps = 55/187 (29%)

Query: 4   GMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP 63
           G  SA+A P      A+    P +        G R  G    GAR      +P PL  R 
Sbjct: 129 GCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLTCR- 187

Query: 64  PGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA 123
                                     RC    P R  R  RRP G PL     +  P   
Sbjct: 188 --------------------------RC-RAAPRRSARPFRRP-GLPL-----KSRPGSG 214

Query: 124 PGRSSALALAGGAAPGVARAQRPG---------------------GSGGRSHPGGPGSPR 162
            G  S      G  PG A A  P                      G GGR    G G+  
Sbjct: 215 TGARSCGTWGSGGGPGTAAASSPSADFSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQP 274

Query: 163 GGGTVGP 169
           G   + P
Sbjct: 275 GCRLLSP 281


>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
           sapiens]
          Length = 384

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 66/209 (31%), Positives = 76/209 (36%), Gaps = 37/209 (17%)

Query: 31  PRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAAR 90
           P    G    G   P +R  P  R P P    PPG  GS        P  RP +    +R
Sbjct: 61  PESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPP--RPSQHQSGSR 118

Query: 91  CLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPG--G 148
              LRP                      AP P PG SSA A    AAP  A    PG   
Sbjct: 119 ---LRP---------------------AAPGPRPGCSSARASPAPAAPQAAARTAPGRAA 154

Query: 149 SGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEG-PVQ 207
           SGG     GPGS RG G+   G R P+ A G  P  T R        +A P    G P++
Sbjct: 155 SGG----SGPGS-RGQGSDQVGAR-PSRAGGQPPPLTCRRCRAAPRRSARPFRRPGLPLK 208

Query: 208 SH--HGTPALTQGPQSPRDGAQLGACTRP 234
           S    GT A + G      G    A + P
Sbjct: 209 SRPGSGTGARSCGTWGSGGGPGTAAASSP 237



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 45/187 (24%), Positives = 52/187 (27%), Gaps = 55/187 (29%)

Query: 4   GMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP 63
           G  SA+A P      A+    P +        G R  G    GAR      +P PL  R 
Sbjct: 129 GCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLTCR- 187

Query: 64  PGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA 123
                                     RC    P R  R  RRP G PL     +  P   
Sbjct: 188 --------------------------RC-RAAPRRSARPFRRP-GLPL-----KSRPGSG 214

Query: 124 PGRSSALALAGGAAPGVARAQRPG---------------------GSGGRSHPGGPGSPR 162
            G  S      G  PG A A  P                      G GGR    G G+  
Sbjct: 215 TGARSCGTWGSGGGPGTAAASSPSADFSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQP 274

Query: 163 GGGTVGP 169
           G   + P
Sbjct: 275 GCRLLSP 281


>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 66/209 (31%), Positives = 76/209 (36%), Gaps = 37/209 (17%)

Query: 31  PRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAAR 90
           P    G    G   P +R  P  R P P    PPG  GS        P  RP +    +R
Sbjct: 61  PESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPP--RPSQHQSGSR 118

Query: 91  CLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPG--G 148
              LRP                      AP P PG SSA A    AAP  A    PG   
Sbjct: 119 ---LRP---------------------AAPGPRPGCSSARASPAPAAPQAAARTAPGRAA 154

Query: 149 SGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEG-PVQ 207
           SGG     GPGS RG G+   G R P+ A G  P  T R        +A P    G P++
Sbjct: 155 SGG----SGPGS-RGQGSDQVGAR-PSRAGGQPPPLTCRRCRAAPRRSARPFRRPGLPLK 208

Query: 208 SH--HGTPALTQGPQSPRDGAQLGACTRP 234
           S    GT A + G      G    A + P
Sbjct: 209 SRPGSGTGARSCGTWGSGGGPGTAAASSP 237



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 45/187 (24%), Positives = 52/187 (27%), Gaps = 55/187 (29%)

Query: 4   GMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP 63
           G  SA+A P      A+    P +        G R  G    GAR      +P PL  R 
Sbjct: 129 GCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLTCR- 187

Query: 64  PGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA 123
                                     RC    P R  R  RRP G PL     +  P   
Sbjct: 188 --------------------------RC-RAAPRRSARPFRRP-GLPL-----KSRPGSG 214

Query: 124 PGRSSALALAGGAAPGVARAQRPG---------------------GSGGRSHPGGPGSPR 162
            G  S      G  PG A A  P                      G GGR    G G+  
Sbjct: 215 TGARSCGTWGSGGGPGTAAASSPSADFSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQP 274

Query: 163 GGGTVGP 169
           G   + P
Sbjct: 275 GCRLLSP 281


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 71/243 (29%), Positives = 81/243 (33%), Gaps = 54/243 (22%)

Query: 25   PCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRR 84
            P  I GP    G     G+ PG R  PGP  P  L   PPG  G         PG     
Sbjct: 1205 PPGIQGPAGLDGLDGKDGK-PGLRGDPGPAGPPGLMG-PPGFKGKT-----GHPGL---- 1253

Query: 85   PHPAARCLPLRPHRPTRRHRRPG-----------GFPLAWGSPQPAPRPAPGRSSALALA 133
            P P   C    P   T R    G           G P   G P P  +P P   SA+ L 
Sbjct: 1254 PGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLK 1313

Query: 134  G--GAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVG-------------PGDRGPAAAD 178
            G  GA      A  PG  G   HPG PG P   G  G             PG +G   A 
Sbjct: 1314 GDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAA 1373

Query: 179  GGRPQRTVRAAETRGAAAAP----------PLTLEGPV--QSHHGTPALTQGPQSPRDGA 226
            G + Q     A  +G A  P          P+   GP   + H G P  +  P  P    
Sbjct: 1374 GQKGQ-----AGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPG 1428

Query: 227  QLG 229
             +G
Sbjct: 1429 SMG 1431



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 63/228 (27%), Positives = 80/228 (35%), Gaps = 51/228 (22%)

Query: 25   PCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRR 84
            P  + G R   GP       PG R  PGP    P P  PPG  G+V  P    PG +  R
Sbjct: 1025 PPGLPGQRGEEGP-------PGMRGSPGP----PGPIGPPGFPGAVGSP--GLPGLQGER 1071

Query: 85   PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQ 144
                                  G   L     +P P   PG   A    G   PG+ + +
Sbjct: 1072 ----------------------GLTGLTGDKGEPGPPGQPGYPGATGPPG--LPGI-KGE 1106

Query: 145  R--PGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGGRPQRTVRAAETRGAAAAPPLT 201
            R   G +G +  PG PGS    G  GP G RG     G   ++  +  + +     PP  
Sbjct: 1107 RGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPP-- 1164

Query: 202  LEGPVQSHHGTPALTQGPQSPRDGAQLGA--CTRPVDVRDSGGRPLPP 247
              GP     G P     P  P   A+ G+     P  +  S G P PP
Sbjct: 1165 --GP----PGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPP 1206



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 46/153 (30%), Positives = 52/153 (33%), Gaps = 35/153 (22%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAA 89
            GP    GP    G L G    PG R   P PA PPG +G         PG + +  HP  
Sbjct: 1204 GPPGIQGPAGLDG-LDGKDGKPGLRGD-PGPAGPPGLMGP--------PGFKGKTGHP-- 1251

Query: 90   RCLPLRPHRPTRRHRRPGGFPLAWGS-PQPAPRPAPGRSSALALAGGAAPGVARAQRPGG 148
                              G P   G   +P P  + GR  A    G   P      RPG 
Sbjct: 1252 ------------------GLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGP----QGRPGP 1289

Query: 149  SGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGR 181
             G    PG PG P   G    G +G   A G R
Sbjct: 1290 PGHVGPPGPPGQPGPAGISAVGLKGDRGATGER 1322



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 38/119 (31%), Positives = 45/119 (37%), Gaps = 29/119 (24%)

Query: 136  AAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVG-------PGDRGPAAADGGRPQRTVRA 188
            AAPG  R   PG  G    PG PGSP   G +G       PG RG     G +    +  
Sbjct: 1470 AAPG--RPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGI 1527

Query: 189  AETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPP 247
            A   G        L GP            GPQ P    ++GA T P+  +   G P PP
Sbjct: 1528 AGENG--------LPGP-----------PGPQGPPGYGKMGA-TGPMGQQGIPGIPGPP 1566



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 53/175 (30%), Positives = 62/175 (35%), Gaps = 33/175 (18%)

Query: 37  PRTPGGQ-LPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGC------RPRRPHPAA 89
           P TPG    PG    PG + PA     P G  G       +  G       RP +P P  
Sbjct: 693 PGTPGTTGRPGLSGEPGVQGPAG----PKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKG 748

Query: 90  RCLPLRPHRPTRRHRRPG--GFPLAWGSP-----QPAPRPAPGRSSALALAGGAAPGVAR 142
              P    RP +    PG  G P   G P     Q  P P PGR          APG+  
Sbjct: 749 EQGPEGVGRPGK----PGQPGLPGVQGPPGLKGVQGEPGP-PGRGVQGPQGEPGAPGLPG 803

Query: 143 AQR-------PGGSGGRSHPGGPGSPRGGGTVGPGDR---GPAAADGGRPQRTVR 187
            Q        PG +G +   G PG     G VGP      GP   DG + Q  +R
Sbjct: 804 IQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLR 858



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 38/138 (27%), Positives = 49/138 (35%), Gaps = 10/138 (7%)

Query: 105 RPG--GFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSG-----GRSHPGG 157
           RPG  G P   G   P      G ++  +L G       R  +PG  G     G   PG 
Sbjct: 701 RPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGK 760

Query: 158 PGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQ 217
           PG P   G  GP        + G P R V+  +  G   AP L     +    G P  T 
Sbjct: 761 PGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQ--GEPGAPGLPGIQGLPGPRGPPGPT- 817

Query: 218 GPQSPRDGAQLGACTRPV 235
           G +  +    +   T PV
Sbjct: 818 GEKGAQGSPGVKGATGPV 835



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 43/143 (30%), Positives = 52/143 (36%), Gaps = 13/143 (9%)

Query: 37  PRTPGGQLPGARRGPGPRRPAPLPARPPGALGS-----VLRPLRARPGCRPRRPHPAARC 91
           P  PG  LPG +  PGPR P P P    GA GS        P+   PG     P      
Sbjct: 796 PGAPG--LPGIQGLPGPRGP-PGPTGEKGAQGSPGVKGATGPV-GPPGASVSGPPGRDGQ 851

Query: 92  LPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGG 151
                 R T   + P G     G P     P+ G      + G     +  + +PG  G 
Sbjct: 852 QGQTGLRGTPGEKGPRGEK---GEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGP 908

Query: 152 RSHPGGPGSPRGGGTVG-PGDRG 173
              PG PG P   G  G PG+ G
Sbjct: 909 PGIPGPPGPPGVPGLQGVPGNNG 931



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 47/179 (26%), Positives = 63/179 (35%), Gaps = 23/179 (12%)

Query: 92   LPLRPHRPTRRHRRPGGFPLAWGSP-QPAPRPAPGRSSALALAGGAAPGVARAQRPGG-S 149
            LP  P  P +R     G P   GSP  P P   PG   A+   G   PG+   +   G +
Sbjct: 1022 LPGPPGLPGQRGEE--GPPGMRGSPGPPGPIGPPGFPGAVGSPG--LPGLQGERGLTGLT 1077

Query: 150  GGRSHPGGPGSPRGGGTVGP-------GDRGPAAADGGRPQRTVRAAETRGAAAAP--PL 200
            G +  PG PG P   G  GP       G+RG   + G + +     +E       P  P 
Sbjct: 1078 GDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPR 1137

Query: 201  TLEGPV--------QSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPPDTL 251
               GP         Q   G P     P  P    ++G+   P    + G   +  P  L
Sbjct: 1138 GERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGL 1196



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 58/209 (27%), Positives = 69/209 (33%), Gaps = 39/209 (18%)

Query: 46   GARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRR 105
            G +  PGP     LP  PPG  G   R  R   G    +     +  P  P  P      
Sbjct: 1114 GEKGEPGPPGSEGLPG-PPGPAGP--RGERGPQGNSGEKGDQGFQGQPGFPGPPG----- 1165

Query: 106  PGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGG 165
            P GFP   GSP P P P   + S                  G  G    PG PG P    
Sbjct: 1166 PPGFPGKVGSPGP-PGPQAEKGSE-----------------GIRGPSGLPGSPGPPG--- 1204

Query: 166  TVGPGDRGPAAADG--GRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPR 223
               PG +GPA  DG  G+  +     +  G A  P L      +   G P L        
Sbjct: 1205 --PPGIQGPAGLDGLDGKDGKPGLRGDP-GPAGPPGLMGPPGFKGKTGHPGLPGPKGDCG 1261

Query: 224  DGAQLGACTRPVDVRDSG-----GRPLPP 247
                 G+  RP    + G     GRP PP
Sbjct: 1262 KPGPPGSTGRPGAEGEPGAMGPQGRPGPP 1290



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 62/238 (26%), Positives = 77/238 (32%), Gaps = 34/238 (14%)

Query: 7   SAQACPCQV--PRAASTTWVPCQICGPRERHG-PRTPGGQLPGARRGP-----GPRRPAP 58
           +A  CP  V   R ++ T  P    G +   G P  PG +     RG       P  P  
Sbjct: 312 AADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQ 371

Query: 59  LPARPPGALG-------SVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPL 111
               P G  G       S L       G +  +     + +P +P R  R    PG   +
Sbjct: 372 CAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGR----PGEICV 427

Query: 112 AWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRG-----GGT 166
                Q      PG      LAG   PG      P G G    PG PG P G     G +
Sbjct: 428 IGPKGQKGD---PGFVGPEGLAG--EPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSS 482

Query: 167 VGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRD 224
             PG  GP    GG+P +     E        P   EG  Q+  G P        P D
Sbjct: 483 GIPGKEGP----GGKPGKPGVKGEKGDPCEVCPTLPEG-FQNFVGLPGKPGPKGEPGD 535



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 46/148 (31%), Positives = 53/148 (35%), Gaps = 30/148 (20%)

Query: 106 PGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGG 165
           P G   A G P     P P  S+   L  G    VA    PG SG +  PG PG    G 
Sbjct: 621 PAGIKGAKGEPC---EPCPALSN---LQDGDVRVVAL---PGPSGEKGEPGPPGFGLPGK 671

Query: 166 TVGPGDRG--PAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPR 223
               G+RG      D G P        T G    P L+         G P + QGP  P+
Sbjct: 672 QGKAGERGLKGQKGDAGNP----GDPGTPGTTGRPGLS---------GEPGV-QGPAGPK 717

Query: 224 DGAQLGACTR----PVDVRDSGGRPLPP 247
            G +   CT        V D  GRP  P
Sbjct: 718 -GEKGDGCTACPSLQGTVTDMAGRPGQP 744



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 40/141 (28%), Positives = 51/141 (36%), Gaps = 20/141 (14%)

Query: 43   QLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRR 102
            ++  A   PGP      P RP GA GS   P   + G   R+  P  R LP      T+ 
Sbjct: 1467 EMAAAPGRPGPPGKDGAPGRP-GAPGSPGLP--GQIGREGRQGLPGVRGLP-----GTKG 1518

Query: 103  HRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPR 162
             +   G  +A  +  P P P P             PG  +    G  G +  PG PG P 
Sbjct: 1519 EKGDIGIGIAGENGLPGP-PGPQ----------GPPGYGKMGATGPMGQQGIPGIPGPPG 1567

Query: 163  GGGTVG-PGDRGPAAADGGRP 182
              G  G  G   P+   G  P
Sbjct: 1568 PMGQPGKAGHCNPSDCFGAMP 1588


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 72/224 (32%), Positives = 87/224 (38%), Gaps = 37/224 (16%)

Query: 16  PRAASTTWVPCQICGPRERHG-PRTPGGQ-LPGARR---GPGPRRPAPLPARPPGALGSV 70
           P+ A     P  + GP+  +G P  PG   LPGAR     PG   P      P GA G  
Sbjct: 526 PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG-KVGPSGAPGED 584

Query: 71  LRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPG-----GFPLAWGSPQPAPRPAPG 125
            RP    PG +  R  P     P     P   +  PG     G P A     P  R  PG
Sbjct: 585 GRP--GPPGPQGARGQPGVMGFP----GPKGANGEPGKAGEKGLPGA-----PGLRGLPG 633

Query: 126 RSSALALAGGAAPGVARAQR-----PGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAA 176
           +      AG   P     +R     PG SG +  PG PG P  GG  G    PG+ G   
Sbjct: 634 KDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG 693

Query: 177 ADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQ 220
             G R +R       RG+  A    L+GP +   GTP  T GP+
Sbjct: 694 LVGPRGERGFPG--ERGSPGAQ--GLQGP-RGLPGTPG-TDGPK 731



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 82/266 (30%), Positives = 92/266 (34%), Gaps = 59/266 (22%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP--PGALGSVLRPLRAR--PGCRPRRP 85
           GP    G R   GQ PG    PGP  PA  P  P  PGA G    P  AR   G +  R 
Sbjct: 336 GPAGAAGARGNDGQ-PGPAGPPGPVGPAGGPGFPGAPGAKGEA-GPTGARGPEGAQGPRG 393

Query: 86  HPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQ----------PAPRPAPGRSSALALA 133
            P     P     P      PG  G P A GS            P PR  PG   A    
Sbjct: 394 EPGTPGSP----GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 449

Query: 134 GGAA----PGVARAQRPGGSGGRSHPGGP----------------GSPRGGGTVG-PGDR 172
           G       PG+A  +   G  G   P GP                G P G G +G PG+R
Sbjct: 450 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509

Query: 173 GPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACT 232
           G A  + G P +   A          P  L GP +  +G P     P  P  GA+ G   
Sbjct: 510 G-APGNRGFPGQDGLAGPKGAPGERGPSGLAGP-KGANGDPGRPGEPGLP--GAR-GLTG 564

Query: 233 RPVDVRDSG-----------GRPLPP 247
           RP D    G           GRP PP
Sbjct: 565 RPGDAGPQGKVGPSGAPGEDGRPGPP 590



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 80/273 (29%), Positives = 90/273 (32%), Gaps = 37/273 (13%)

Query: 6    GSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQ--LPGA--RRGPGPRRPAPLPA 61
            G A A   Q P  A     P  + GP+   G + P G    PGA  R GP      P P 
Sbjct: 858  GDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 917

Query: 62   RPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPR 121
             PPG  G    P  AR    P  P  A       P  P      PG    +     P P+
Sbjct: 918  GPPGPSGKD-GPKGARGDSGP--PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 974

Query: 122  PAPGRSSALALAGGAA----PGV-------ARAQRPGGSGGRSHPGGPGSPRGGGTVG-- 168
               G+   + L G       PG+        +   PG SG R  PG  G P   G  G  
Sbjct: 975  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 1034

Query: 169  -----PGDRGPAAADGGRPQRTVRAAETRGAAAAP----PLTLEGPV-----QSHHGTPA 214
                 PG  GP   DG    +  R  ET GA  AP    P    GP      Q   G  A
Sbjct: 1035 GREGSPGADGPPGRDGAAGVKGDR-GET-GAVGAPGAPGPPGSPGPAGPTGKQGDRG-EA 1091

Query: 215  LTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPP 247
              QGP  P   A       P   R   G    P
Sbjct: 1092 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1124



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 57/169 (33%), Positives = 61/169 (36%), Gaps = 26/169 (15%)

Query: 30  GPRERHGPRTPGGQL--PGARRGPGPRRPA--PLPARPPGALGSVLRPLRARPGCRPRRP 85
           GP+   GP  P GQ   PG     G + P   P PA P GA G          G R  R 
Sbjct: 441 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA-----GEEGKRGARG 495

Query: 86  HPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAG--GAAPGVA 141
            P      + P  P      PG  GFP   G     P+ APG      LAG  GA     
Sbjct: 496 EPGG----VGPIGPPGERGAPGNRGFPGQDGLA--GPKGAPGERGPSGLAGPKGANGDPG 549

Query: 142 RAQRPGGSGGRSHPGGPGSPRGGGTVGP-------GDRGPAAADGGRPQ 183
           R   PG  G R   G PG     G VGP       G  GP    G R Q
Sbjct: 550 RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 70/246 (28%), Positives = 84/246 (34%), Gaps = 43/246 (17%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAA 89
           G +   GPR   G+ PG    PGP  P P P  PPG  G+    +      +        
Sbjct: 141 GEKGAPGPRGRDGE-PGTPGNPGPPGP-PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198

Query: 90  RCLPLRPHRPTRRHRRPGGFPLAWG-------------SPQPAPRPAPGRSSALALAGGA 136
              P+ P  P R    P G P   G             S    PR  PG        G A
Sbjct: 199 MQGPMGPMGP-RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 257

Query: 137 A-PGVARAQRPGG-SGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGA 194
             PG A  + P G  G R  PG PG P        G RG    DG            +G 
Sbjct: 258 GKPGKAGERGPPGPQGARGFPGTPGLPG-----VKGHRGYPGLDG-----------AKGE 301

Query: 195 AAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRP---VDVRDSGGRPLP--PPD 249
           A AP +  E      +G+P    GP  PR        T P      R + G+P P  PP 
Sbjct: 302 AGAPGVKGESGSPGENGSP----GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 357

Query: 250 TLASAG 255
            +  AG
Sbjct: 358 PVGPAG 363



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 76/258 (29%), Positives = 90/258 (34%), Gaps = 44/258 (17%)

Query: 6    GSAQACPCQVPRAASTTWVPCQICGPRERHG-PRTPGGQLPGARRG----PGPRRP--AP 58
            GSA A      R  +    P    GP    G P   G Q    ++G    PGP+ P  AP
Sbjct: 813  GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 872

Query: 59   LPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQP 118
             P  P G  G          G R  +  P A   P    R         G P + G+P P
Sbjct: 873  GPQGPTGVTGP--------KGARGAQGPPGATGFPGAAGRV--------GPPGSNGNPGP 916

Query: 119  APRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAAD 178
               P P        A G +    RA  PG  G    P GP   +G     PGD GP+ A+
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQG----PAGPPGEKG----EPGDDGPSGAE 968

Query: 179  GGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVR 238
            G  P      A  RG    P        +   G P L  GP S   G Q GA     D  
Sbjct: 969  G--PPGPQGLAGQRGIVGLP------GQRGERGFPGL-PGP-SGEPGKQ-GAPGASGDRG 1017

Query: 239  DSGGRPLPPPDTLASAGD 256
              G  P+ PP     AG+
Sbjct: 1018 PPG--PVGPPGLTGPAGE 1033



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 62/223 (27%), Positives = 75/223 (33%), Gaps = 46/223 (20%)

Query: 26  CQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRP 85
           C IC          PG +  G +  PG  +    P  PPG  G          G R  R 
Sbjct: 86  CPICPTDLATASGQPGPK--GQKGEPGDIKDIVGPKGPPGPQGPA-----GEQGPRGDRG 138

Query: 86  HPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAGG-------- 135
               +  P     P  R   PG  G P   G P P   P  G + A  +AGG        
Sbjct: 139 DKGEKGAP----GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGA 194

Query: 136 ---------------AAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAA--A 177
                            PG A A  PG  G + +PG PG P   G +GP G  GP     
Sbjct: 195 QLGVMQGPMGPMGPRGPPGPAGA--PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG 252

Query: 178 DGGRPQRTVRAAE-----TRGAAAAPPLTLEGPVQSHHGTPAL 215
           D G   +  +A E      +GA   P       V+ H G P L
Sbjct: 253 DDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGL 295



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 53/203 (26%), Positives = 70/203 (34%), Gaps = 15/203 (7%)

Query: 30   GPRERHGPR-TPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPA 88
            GP  + G R   G Q P    GP   R    P  P G  G         PG R  + H  
Sbjct: 1080 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA-----GEPGERGLKGHRG 1134

Query: 89   ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA--PGRSSALALAGGAAPGVARAQRP 146
               L   P  P     +    P     P+  P P    G+  A  + G   P   R  R 
Sbjct: 1135 FTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG-RS 1193

Query: 147  GGSGGRSHPGGPGSPRGGGTVGPG-DRGPAAADGGR-----PQRTVRAAETRGAAAAPPL 200
            G +G    PG PG P   G  GPG D    A  G R     P + +RA +  G       
Sbjct: 1194 GETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDA 1253

Query: 201  TLEGPVQSHHGTPALTQGPQSPR 223
             ++  ++S +      + P+  R
Sbjct: 1254 EVDATLKSLNNQIESIRSPEGSR 1276



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 50/156 (32%), Positives = 55/156 (35%), Gaps = 29/156 (18%)

Query: 36  GPRTPGGQLPGARRGPGPRRPA--------PLPARPPGALGSVLRP-LRARPGCRPRRPH 86
           GP  P G LPG R   GP   A        P PA PPG +G    P     PG +     
Sbjct: 321 GPMGPRG-LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379

Query: 87  PAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA-PGRSSALALAGGA-APGVARAQ 144
             AR             + P G P   GSP PA     PG        G A APG+A   
Sbjct: 380 TGAR--------GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA--- 428

Query: 145 RPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG 179
                G    PG  G P   G  GP G +G     G
Sbjct: 429 -----GAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 65/246 (26%), Positives = 77/246 (31%), Gaps = 32/246 (13%)

Query: 30  GPRERHGPRTPGGQL--PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHP 87
           GP+   GP  P G    PG +  PG R  A + A P G  G V       P   P +   
Sbjct: 729 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGI-AGPKGDRGDVGEK---GPEGAPGKDGG 784

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPA----PRPAPGRSSALAL---AGGAAPGV 140
                P+ P  P   +   G      G P PA     R APG          AG A P  
Sbjct: 785 RGLTGPIGPPGPAGANGEKGEV----GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840

Query: 141 ARAQ-----RPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADGGRPQRTVRAAET 191
           A  Q       G +G +   G PG     G  GP    G  GP  A G +          
Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900

Query: 192 RGAAAAPPLTLEGPVQSHHGTPALTQGPQSPR-DGAQLGACTRPVDVRDSGGRPLPPPDT 250
                 PP +   P       P+   GP+  R D    G    P         P  PP  
Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP-----GLQGPAGPPGE 955

Query: 251 LASAGD 256
               GD
Sbjct: 956 KGEPGD 961



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 51/168 (30%), Positives = 59/168 (35%), Gaps = 23/168 (13%)

Query: 31  PRERHGPRTPGGQLPGARRGPGPRR-PAPLPAR-PPGALGSVLRPLRARPGCR--PRRPH 86
           P E   P  PG Q  GAR  PG    P P  A   PG  G   + L   PG R  P +  
Sbjct: 581 PGEDGRPGPPGPQ--GARGQPGVMGFPGPKGANGEPGKAGE--KGLPGAPGLRGLPGKDG 636

Query: 87  PAARCLPLRPHRPTRRHRRPG--------GFPLAWGSP----QPAPRPAPGRSSALALAG 134
                 P  P  P       G        G P   G P    +P  +  PG + A  L G
Sbjct: 637 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 696

Query: 135 GAAPGVARAQR--PGGSGGRSHPGGPGSPRGGGTVG-PGDRGPAAADG 179
                    +R  PG  G +   G PG+P   G  G  G  GP  A G
Sbjct: 697 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG 744



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 47/165 (28%), Positives = 59/165 (35%), Gaps = 29/165 (17%)

Query: 33  ERHGPRTPGGQ-LPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARC 91
           E+  P  PG + LPG     G   P P PA P G  G      +  PG    +  P    
Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGP-PGPAGPAGERGE-----QGAPGPSGFQGLPG--- 669

Query: 92  LPLRPHRPTRRHRRPG--GFPLAWGSPQ----------PAPRPAPGRSSALALAGGAAPG 139
               P  P     +PG  G P   G+P           P  R +PG        G   PG
Sbjct: 670 ----PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG--LPG 723

Query: 140 VARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQR 184
                 P G+ G + P G   P G   + PG+RG A   G +  R
Sbjct: 724 TPGTDGPKGASGPAGPPGAQGPPGLQGM-PGERGAAGIAGPKGDR 767


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 72/224 (32%), Positives = 87/224 (38%), Gaps = 37/224 (16%)

Query: 16  PRAASTTWVPCQICGPRERHG-PRTPGGQ-LPGARR---GPGPRRPAPLPARPPGALGSV 70
           P+ A     P  + GP+  +G P  PG   LPGAR     PG   P      P GA G  
Sbjct: 457 PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG-KVGPSGAPGED 515

Query: 71  LRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPG-----GFPLAWGSPQPAPRPAPG 125
            RP    PG +  R  P     P     P   +  PG     G P A     P  R  PG
Sbjct: 516 GRP--GPPGPQGARGQPGVMGFP----GPKGANGEPGKAGEKGLPGA-----PGLRGLPG 564

Query: 126 RSSALALAGGAAPGVARAQR-----PGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAA 176
           +      AG   P     +R     PG SG +  PG PG P  GG  G    PG+ G   
Sbjct: 565 KDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG 624

Query: 177 ADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQ 220
             G R +R       RG+  A    L+GP +   GTP  T GP+
Sbjct: 625 LVGPRGERGFPG--ERGSPGAQ--GLQGP-RGLPGTPG-TDGPK 662



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 82/266 (30%), Positives = 92/266 (34%), Gaps = 59/266 (22%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP--PGALGSVLRPLRAR--PGCRPRRP 85
           GP    G R   GQ PG    PGP  PA  P  P  PGA G    P  AR   G +  R 
Sbjct: 267 GPAGAAGARGNDGQ-PGPAGPPGPVGPAGGPGFPGAPGAKGEA-GPTGARGPEGAQGPRG 324

Query: 86  HPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQ----------PAPRPAPGRSSALALA 133
            P     P     P      PG  G P A GS            P PR  PG   A    
Sbjct: 325 EPGTPGSP----GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380

Query: 134 GGAA----PGVARAQRPGGSGGRSHPGGP----------------GSPRGGGTVG-PGDR 172
           G       PG+A  +   G  G   P GP                G P G G +G PG+R
Sbjct: 381 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440

Query: 173 GPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACT 232
           G A  + G P +   A          P  L GP +  +G P     P  P  GA+ G   
Sbjct: 441 G-APGNRGFPGQDGLAGPKGAPGERGPSGLAGP-KGANGDPGRPGEPGLP--GAR-GLTG 495

Query: 233 RPVDVRDSG-----------GRPLPP 247
           RP D    G           GRP PP
Sbjct: 496 RPGDAGPQGKVGPSGAPGEDGRPGPP 521



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 80/273 (29%), Positives = 90/273 (32%), Gaps = 37/273 (13%)

Query: 6    GSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQ--LPGA--RRGPGPRRPAPLPA 61
            G A A   Q P  A     P  + GP+   G + P G    PGA  R GP      P P 
Sbjct: 789  GDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 848

Query: 62   RPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPR 121
             PPG  G    P  AR    P  P  A       P  P      PG    +     P P+
Sbjct: 849  GPPGPSGKD-GPKGARGDSGP--PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 905

Query: 122  PAPGRSSALALAGGAA----PGV-------ARAQRPGGSGGRSHPGGPGSPRGGGTVG-- 168
               G+   + L G       PG+        +   PG SG R  PG  G P   G  G  
Sbjct: 906  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 965

Query: 169  -----PGDRGPAAADGGRPQRTVRAAETRGAAAAP----PLTLEGPV-----QSHHGTPA 214
                 PG  GP   DG    +  R  ET GA  AP    P    GP      Q   G  A
Sbjct: 966  GREGSPGADGPPGRDGAAGVKGDR-GET-GAVGAPGAPGPPGSPGPAGPTGKQGDRG-EA 1022

Query: 215  LTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPP 247
              QGP  P   A       P   R   G    P
Sbjct: 1023 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1055



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 57/169 (33%), Positives = 61/169 (36%), Gaps = 26/169 (15%)

Query: 30  GPRERHGPRTPGGQL--PGARRGPGPRRPA--PLPARPPGALGSVLRPLRARPGCRPRRP 85
           GP+   GP  P GQ   PG     G + P   P PA P GA G          G R  R 
Sbjct: 372 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA-----GEEGKRGARG 426

Query: 86  HPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAG--GAAPGVA 141
            P      + P  P      PG  GFP   G     P+ APG      LAG  GA     
Sbjct: 427 EPGG----VGPIGPPGERGAPGNRGFPGQDGLA--GPKGAPGERGPSGLAGPKGANGDPG 480

Query: 142 RAQRPGGSGGRSHPGGPGSPRGGGTVGP-------GDRGPAAADGGRPQ 183
           R   PG  G R   G PG     G VGP       G  GP    G R Q
Sbjct: 481 RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 70/246 (28%), Positives = 84/246 (34%), Gaps = 43/246 (17%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAA 89
           G +   GPR   G+ PG    PGP  P P P  PPG  G+    +      +        
Sbjct: 72  GEKGAPGPRGRDGE-PGTPGNPGPPGP-PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129

Query: 90  RCLPLRPHRPTRRHRRPGGFPLAWG-------------SPQPAPRPAPGRSSALALAGGA 136
              P+ P  P R    P G P   G             S    PR  PG        G A
Sbjct: 130 MQGPMGPMGP-RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188

Query: 137 A-PGVARAQRPGG-SGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGA 194
             PG A  + P G  G R  PG PG P        G RG    DG            +G 
Sbjct: 189 GKPGKAGERGPPGPQGARGFPGTPGLPG-----VKGHRGYPGLDG-----------AKGE 232

Query: 195 AAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRP---VDVRDSGGRPLP--PPD 249
           A AP +  E      +G+P    GP  PR        T P      R + G+P P  PP 
Sbjct: 233 AGAPGVKGESGSPGENGSP----GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 288

Query: 250 TLASAG 255
            +  AG
Sbjct: 289 PVGPAG 294



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 76/258 (29%), Positives = 90/258 (34%), Gaps = 44/258 (17%)

Query: 6   GSAQACPCQVPRAASTTWVPCQICGPRERHG-PRTPGGQLPGARRG----PGPRRP--AP 58
           GSA A      R  +    P    GP    G P   G Q    ++G    PGP+ P  AP
Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 803

Query: 59  LPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQP 118
            P  P G  G          G R  +  P A   P    R         G P + G+P P
Sbjct: 804 GPQGPTGVTGP--------KGARGAQGPPGATGFPGAAGRV--------GPPGSNGNPGP 847

Query: 119 APRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAAD 178
              P P        A G +    RA  PG  G    P GP   +G     PGD GP+ A+
Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQG----PAGPPGEKG----EPGDDGPSGAE 899

Query: 179 GGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVR 238
           G  P      A  RG    P        +   G P L  GP S   G Q GA     D  
Sbjct: 900 G--PPGPQGLAGQRGIVGLP------GQRGERGFPGL-PGP-SGEPGKQ-GAPGASGDRG 948

Query: 239 DSGGRPLPPPDTLASAGD 256
             G  P+ PP     AG+
Sbjct: 949 PPG--PVGPPGLTGPAGE 964



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 60/211 (28%), Positives = 73/211 (34%), Gaps = 46/211 (21%)

Query: 38  RTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPH 97
           R PG +  G +  PG  +    P  PPG  G          G R  R     +  P    
Sbjct: 29  RQPGPK--GQKGEPGDIKDIVGPKGPPGPQGPA-----GEQGPRGDRGDKGEKGAP---- 77

Query: 98  RPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAGG-------------------- 135
            P  R   PG  G P   G P P   P  G + A  +AGG                    
Sbjct: 78  GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 137

Query: 136 ---AAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAA--ADGGRPQRTVRAA 189
                PG A A  PG  G + +PG PG P   G +GP G  GP     D G   +  +A 
Sbjct: 138 GPRGPPGPAGA--PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAG 195

Query: 190 E-----TRGAAAAPPLTLEGPVQSHHGTPAL 215
           E      +GA   P       V+ H G P L
Sbjct: 196 ERGPPGPQGARGFPGTPGLPGVKGHRGYPGL 226



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 53/203 (26%), Positives = 70/203 (34%), Gaps = 15/203 (7%)

Query: 30   GPRERHGPR-TPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPA 88
            GP  + G R   G Q P    GP   R    P  P G  G         PG R  + H  
Sbjct: 1011 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA-----GEPGERGLKGHRG 1065

Query: 89   ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA--PGRSSALALAGGAAPGVARAQRP 146
               L   P  P     +    P     P+  P P    G+  A  + G   P   R  R 
Sbjct: 1066 FTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG-RS 1124

Query: 147  GGSGGRSHPGGPGSPRGGGTVGPG-DRGPAAADGGR-----PQRTVRAAETRGAAAAPPL 200
            G +G    PG PG P   G  GPG D    A  G R     P + +RA +  G       
Sbjct: 1125 GETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDA 1184

Query: 201  TLEGPVQSHHGTPALTQGPQSPR 223
             ++  ++S +      + P+  R
Sbjct: 1185 EVDATLKSLNNQIESIRSPEGSR 1207



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 50/156 (32%), Positives = 55/156 (35%), Gaps = 29/156 (18%)

Query: 36  GPRTPGGQLPGARRGPGPRRPA--------PLPARPPGALGSVLRP-LRARPGCRPRRPH 86
           GP  P G LPG R   GP   A        P PA PPG +G    P     PG +     
Sbjct: 252 GPMGPRG-LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310

Query: 87  PAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA-PGRSSALALAGGA-APGVARAQ 144
             AR             + P G P   GSP PA     PG        G A APG+A   
Sbjct: 311 TGAR--------GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA--- 359

Query: 145 RPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG 179
                G    PG  G P   G  GP G +G     G
Sbjct: 360 -----GAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 65/246 (26%), Positives = 77/246 (31%), Gaps = 32/246 (13%)

Query: 30  GPRERHGPRTPGGQL--PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHP 87
           GP+   GP  P G    PG +  PG R  A + A P G  G V       P   P +   
Sbjct: 660 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGI-AGPKGDRGDVGEK---GPEGAPGKDGG 715

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPA----PRPAPGRSSALAL---AGGAAPGV 140
                P+ P  P   +   G      G P PA     R APG          AG A P  
Sbjct: 716 RGLTGPIGPPGPAGANGEKGEV----GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 771

Query: 141 ARAQ-----RPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADGGRPQRTVRAAET 191
           A  Q       G +G +   G PG     G  GP    G  GP  A G +          
Sbjct: 772 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831

Query: 192 RGAAAAPPLTLEGPVQSHHGTPALTQGPQSPR-DGAQLGACTRPVDVRDSGGRPLPPPDT 250
                 PP +   P       P+   GP+  R D    G    P         P  PP  
Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP-----GLQGPAGPPGE 886

Query: 251 LASAGD 256
               GD
Sbjct: 887 KGEPGD 892



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 51/168 (30%), Positives = 59/168 (35%), Gaps = 23/168 (13%)

Query: 31  PRERHGPRTPGGQLPGARRGPGPRR-PAPLPAR-PPGALGSVLRPLRARPGCR--PRRPH 86
           P E   P  PG Q  GAR  PG    P P  A   PG  G   + L   PG R  P +  
Sbjct: 512 PGEDGRPGPPGPQ--GARGQPGVMGFPGPKGANGEPGKAGE--KGLPGAPGLRGLPGKDG 567

Query: 87  PAARCLPLRPHRPTRRHRRPG--------GFPLAWGSP----QPAPRPAPGRSSALALAG 134
                 P  P  P       G        G P   G P    +P  +  PG + A  L G
Sbjct: 568 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627

Query: 135 GAAPGVARAQR--PGGSGGRSHPGGPGSPRGGGTVG-PGDRGPAAADG 179
                    +R  PG  G +   G PG+P   G  G  G  GP  A G
Sbjct: 628 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG 675



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 47/165 (28%), Positives = 59/165 (35%), Gaps = 29/165 (17%)

Query: 33  ERHGPRTPGGQ-LPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARC 91
           E+  P  PG + LPG     G   P P PA P G  G      +  PG    +  P    
Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGP-PGPAGPAGERGE-----QGAPGPSGFQGLPG--- 600

Query: 92  LPLRPHRPTRRHRRPG--GFPLAWGSPQ----------PAPRPAPGRSSALALAGGAAPG 139
               P  P     +PG  G P   G+P           P  R +PG        G   PG
Sbjct: 601 ----PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG--LPG 654

Query: 140 VARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQR 184
                 P G+ G + P G   P G   + PG+RG A   G +  R
Sbjct: 655 TPGTDGPKGASGPAGPPGAQGPPGLQGM-PGERGAAGIAGPKGDR 698


>gi|113427525 PREDICTED: similar to hCG2037003 [Homo sapiens]
          Length = 196

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 53/147 (36%), Positives = 61/147 (41%), Gaps = 20/147 (13%)

Query: 51  PGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFP 110
           PGP  P P PA              ARP  R   P   AR   L   +  RR   PG   
Sbjct: 19  PGPETPPPAPAPT------------ARPRLRLPAPDWRARRADLTRRKGLRRGE-PGSRG 65

Query: 111 LAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSG---GRSHPGGPGSPRGGGTV 167
           L  G P  A RP   +S     +G  AP  +RAQRPG SG     +    PG     G++
Sbjct: 66  LGEG-PAAARRPQV-QSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSL 123

Query: 168 GPGDRGPA--AADGGRPQRTVRAAETR 192
            PG R  A  +  GGR  R  RAAE R
Sbjct: 124 RPGKRQQALESEAGGRASREARAAEVR 150


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 73/239 (30%), Positives = 90/239 (37%), Gaps = 27/239 (11%)

Query: 36   GPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRP-LRARPGCRPRRPHPAARCLP- 93
            GP  P G  P   RGP     A  P  PPG +G++  P  +  PG       P  +  P 
Sbjct: 1088 GPMGPPG--PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG---ESGSPGIQGEPG 1142

Query: 94   LRPHRPTRRHRRPGGFPLAWGSPQP-------APRPAPGRSSALALAGGAAPGVARAQ-- 144
            ++  R  R  +   G P   G P P        P+  PG        G    G  R Q  
Sbjct: 1143 VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG 1202

Query: 145  RPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADGGRPQRTVRAAE-TRGAAAAPP 199
              G  G    PG PGSP   G  GP    G RGPA + G   ++  + A+   GA  AP 
Sbjct: 1203 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1262

Query: 200  LTLEGPVQSHHGTPALTQGPQSPRD-GAQLGACTRPVDVRDSG-GRPLPPPDTLASAGD 256
             T  GPV      PA   GP   R     +G   RP     +G   P+ PP      GD
Sbjct: 1263 KT--GPVGP--AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1317



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 68/236 (28%), Positives = 81/236 (34%), Gaps = 47/236 (19%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPRRPA--PLPARPPGALGSVLRPLRARPGCRPRRPHP 87
            GPR   G +   GQ PG    PGP+ P     P   PG +G             P  P P
Sbjct: 1145 GPRGERGEKGESGQ-PGEPGPPGPKGPTGDDGPKGNPGPVGF------------PGDPGP 1191

Query: 88   AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGA-APGVARAQRP 146
                 P R     +  R   G P   GSP P     P     L   G A +PG     R 
Sbjct: 1192 PGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGP--PGPLGKRGPAGSPG--SEGRQ 1246

Query: 147  GGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG-----------GRPQRTVRAAETR-- 192
            GG G +  PG  G+P   G VGP G  G    DG           GRP  T +A      
Sbjct: 1247 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1306

Query: 193  GAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPP 248
            G    P L  +   +   G P L            +G    P +  + G R LP P
Sbjct: 1307 GPPGLPGLRGDAGAKGEKGHPGL------------IGLIGPPGEQGEKGDRGLPGP 1350



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/192 (30%), Positives = 72/192 (37%), Gaps = 24/192 (12%)

Query: 25   PCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRP-LRARPGCRPR 83
            P    GP  + GP    G LPG+    G R  A   A PPG +G    P LR   G +  
Sbjct: 1266 PVGPAGPAGKPGPDGLRG-LPGSVGQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323

Query: 84   RPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSP-QPAPRPAPGRSSALALAGGAAPGVAR 142
            + HP    L   P     +  R  G P   GSP Q      PG S  +    G  PG+  
Sbjct: 1324 KGHPGLIGLIGPPGEQGEKGDR--GLPGPQGSPGQKGEMGIPGASGPIG--PGGPPGLPG 1379

Query: 143  AQRPGGSGGRSHPGGPGSPRG--GGTVGPGDRGPA--------------AADGGRPQRTV 186
               P G+ G + PGGP   +G  G    PG  G                + DG R  +  
Sbjct: 1380 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1439

Query: 187  RAAETRGAAAAP 198
             A  T GA  +P
Sbjct: 1440 EAIPTGGAPGSP 1451



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 50/155 (32%), Positives = 60/155 (38%), Gaps = 21/155 (13%)

Query: 31   PRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSV-----LRPLRARPGCRPRRP 85
            P ER  P T GG  PG +   GP  P P PA  PG  G+      + P   RPG  P+ P
Sbjct: 901  PGERGLPGTAGG--PGLKGNEGPSGP-PGPAGSPGERGAAGSGGPIGP-PGRPG--PQGP 954

Query: 86   HPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQR 145
              AA        +     + P G     G   P   P P     +A   G    V    +
Sbjct: 955  PGAAG------EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ 1008

Query: 146  PGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG 179
             G  G +   G PG P   G +GP G  G A ADG
Sbjct: 1009 KGTKGNKGEHGPPGPP---GPIGPVGQPGAAGADG 1040



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 54/203 (26%), Positives = 66/203 (32%), Gaps = 18/203 (8%)

Query: 25   PCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRR 84
            P  + GP+   G   P G+    R  PGP  P P     PG  G         P   P +
Sbjct: 837  PPGVVGPQGAAGETGPMGE----RGHPGPPGP-PGEQGLPGTAGKEGTKGDPGPPGAPGK 891

Query: 85   PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQ 144
              PA     LR     R      G P   G+  P+  P P  S     A G+   +    
Sbjct: 892  DGPAG----LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 947

Query: 145  RPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADG-GRPQRTVRAAETRGAAAAPP 199
            RPG  G     G  G P   G +GP    G +GP    G   P         +G    P 
Sbjct: 948  RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG 1007

Query: 200  LTLEGPVQSHHGTPALTQGPQSP 222
                   +  HG P    GP  P
Sbjct: 1008 QKGTKGNKGEHGPP----GPPGP 1026



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 49/161 (30%), Positives = 57/161 (35%), Gaps = 32/161 (19%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPL--PARPPGALGSVLRPLRARPGCR----PR 83
           GP    G R   G++ G R  PG   P  L  P  PPG  G         PG R    P+
Sbjct: 497 GPPGEDGERGDDGEI-GPRGLPGESGPRGLLGPKGPPGIPGP--------PGVRGMDGPQ 547

Query: 84  RPHPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVA 141
            P  +    P     P  +   PG  G P   G+  P     P     L       PG+ 
Sbjct: 548 GPKGSLG--PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGL-------PGM- 597

Query: 142 RAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGGR 181
               PG  G   HPG  G P   G  GP G +GP    G R
Sbjct: 598 ----PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 634



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 49/158 (31%), Positives = 55/158 (34%), Gaps = 21/158 (13%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP--PGALGSVLRPLRARPGCRPRRPHP 87
           GP+ R GP    G  PG     G      LP  P   G  GS+       PG        
Sbjct: 686 GPKGRTGPTGDPGP-PGLMGEKGKLGVPGLPGYPGRQGPKGSL-----GFPGFPGASGEK 739

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQR-- 145
            AR L  +     R  R P G        Q  PR A G+S A   +GG  P     +R  
Sbjct: 740 GARGLSGKSG--PRGERGPTG-----PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL 792

Query: 146 PGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAAADG 179
           PG  G    PG  G P   G  G    PG RG     G
Sbjct: 793 PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 830



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 47/166 (28%), Positives = 58/166 (34%), Gaps = 20/166 (12%)

Query: 30  GPRERHGPRTPGGQ--LPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHP 87
           GP    G R P G+  LPG+   PGP   + +     G+ G    P+ A    + +    
Sbjct: 334 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 393

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPG-------- 139
            AR     P  P     RPG  PL     QP      G S  L   G   P         
Sbjct: 394 QARLALRGPPGPMGYTGRPG--PLG----QPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 447

Query: 140 VARAQRPGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAAADGGR 181
             R  R G  G R  PG PG     G  G    PG++G     G +
Sbjct: 448 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 493



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 72/282 (25%), Positives = 88/282 (31%), Gaps = 61/282 (21%)

Query: 16   PRAASTTWVPCQI--CGPRERHGPRTPGGQLPGARRGPGP-------------------- 53
            P AA    VP +    GP  R G + P G LPG    PG                     
Sbjct: 955  PGAAGEKGVPGEKGPIGPTGRDGVQGPVG-LPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1013

Query: 54   RRPAPLPARPPGALGSVLRPLRA----RPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGF 109
             +    P  PPG +G V +P  A     PG R  + H  A+         TR    P G 
Sbjct: 1014 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK-----GDEGTRGFNGPPGP 1068

Query: 110  PLAWGSPQPA----------PRPAPGRSSALALAG--------GAAPGVARAQRPGGSGG 151
                G P P+          P   PG       AG        G   GV     PG  G 
Sbjct: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128

Query: 152  RSHPGGPGSPRGGGTVGP-GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHH 210
                G PG     G  GP G+RG     G       +  E        P   +GP + + 
Sbjct: 1129 PGESGSPGIQGEPGVKGPRGERGEKGESG-------QPGEPGPPGPKGPTGDDGP-KGNP 1180

Query: 211  GTPALTQGPQSPRDGAQLGACTRPVDVRDSG--GRPLPPPDT 250
            G       P  P +G   G      D  + G  G+P  P  T
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1222



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 21/168 (12%)

Query: 30  GPRERHGPRTPGGQL-PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPH-P 87
           G R   GP+ P G L P    GP  ++  P     PG  G++       P  +P  P  P
Sbjct: 539 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 598

Query: 88  AARCLPLRPHRP----TRRHRRPGG--FPLAWGSPQPAPRPAPGRSSALALAGGAA---- 137
            +   P  P +     T+ ++ P G   PL +    P PR   G      L G       
Sbjct: 599 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY----PGPRGVKGVDGIRGLKGHKGEKGE 654

Query: 138 ---PGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRP 182
              PG       G  G R   G PGS    G  GP  R     D G P
Sbjct: 655 DGFPGFKGDI--GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 37/126 (29%), Positives = 43/126 (34%), Gaps = 30/126 (23%)

Query: 124 PGRSSALALAGGAAPGVARAQRP-GGSGGRSHPGGPGSPRGGGTVGP------------- 169
           PG      L G   PG+     P G  G R  PG  G P   G  GP             
Sbjct: 315 PGPEGPAGLIG--PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 372

Query: 170 --GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTL-----EGPVQSHHGTPAL-----TQ 217
             GD+GP  A     Q      + R A   PP  +      GP+    G+P L       
Sbjct: 373 GGGDKGPVVA-AQEAQAQAILQQARLALRGPPGPMGYTGRPGPL-GQPGSPGLKGESGDL 430

Query: 218 GPQSPR 223
           GPQ PR
Sbjct: 431 GPQGPR 436



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 47/157 (29%), Positives = 54/157 (34%), Gaps = 28/157 (17%)

Query: 37  PRTPGGQLPGARRGP-GPRRPAPLPARPPGALG-------SVLRPLRARPGCRPRRPHPA 88
           P +PG +      GP GPR P  L   PPG  G          R +   PG +  R    
Sbjct: 418 PGSPGLKGESGDLGPQGPRGPQGLTG-PPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 476

Query: 89  ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAP-GVARAQRPG 147
              LP       + HR   G   A G P P     PG        G   P G+     P 
Sbjct: 477 LPGLP-----GEKGHRGDTG---AQGLPGP-----PGEDGERGDDGEIGPRGLPGESGPR 523

Query: 148 GS-GGRSHPGGPGSPRGGGTVGP----GDRGPAAADG 179
           G  G +  PG PG P   G  GP    G  GP    G
Sbjct: 524 GLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 560



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 48/175 (27%), Positives = 60/175 (34%), Gaps = 25/175 (14%)

Query: 30  GPRERHGPR----TPGGQ-LPGARRGPGP---RRPAPLPARP--PGALGSVLRPLRARPG 79
           GP+   GP     TPG Q LPG +   GP   + P   P  P  PG+ G    P +  P 
Sbjct: 554 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 613

Query: 80  CRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGG---- 135
                  P+    PL    P       G   L     +      PG    + + G     
Sbjct: 614 GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 673

Query: 136 AAPGVARAQRPGGSGGRSHPGG-PGSPRGGGTVG----------PGDRGPAAADG 179
             PG      P G  GR+ P G PG P   G  G          PG +GP  + G
Sbjct: 674 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 728


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 73/239 (30%), Positives = 90/239 (37%), Gaps = 27/239 (11%)

Query: 36   GPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRP-LRARPGCRPRRPHPAARCLP- 93
            GP  P G  P   RGP     A  P  PPG +G++  P  +  PG       P  +  P 
Sbjct: 1067 GPMGPPG--PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG---ESGSPGIQGEPG 1121

Query: 94   LRPHRPTRRHRRPGGFPLAWGSPQP-------APRPAPGRSSALALAGGAAPGVARAQ-- 144
            ++  R  R  +   G P   G P P        P+  PG        G    G  R Q  
Sbjct: 1122 VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG 1181

Query: 145  RPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADGGRPQRTVRAAE-TRGAAAAPP 199
              G  G    PG PGSP   G  GP    G RGPA + G   ++  + A+   GA  AP 
Sbjct: 1182 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1241

Query: 200  LTLEGPVQSHHGTPALTQGPQSPRD-GAQLGACTRPVDVRDSG-GRPLPPPDTLASAGD 256
             T  GPV      PA   GP   R     +G   RP     +G   P+ PP      GD
Sbjct: 1242 KT--GPVGP--AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1296



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 68/236 (28%), Positives = 81/236 (34%), Gaps = 47/236 (19%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPRRPA--PLPARPPGALGSVLRPLRARPGCRPRRPHP 87
            GPR   G +   GQ PG    PGP+ P     P   PG +G             P  P P
Sbjct: 1124 GPRGERGEKGESGQ-PGEPGPPGPKGPTGDDGPKGNPGPVGF------------PGDPGP 1170

Query: 88   AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGA-APGVARAQRP 146
                 P R     +  R   G P   GSP P     P     L   G A +PG     R 
Sbjct: 1171 PGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGP--PGPLGKRGPAGSPG--SEGRQ 1225

Query: 147  GGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG-----------GRPQRTVRAAETR-- 192
            GG G +  PG  G+P   G VGP G  G    DG           GRP  T +A      
Sbjct: 1226 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1285

Query: 193  GAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPP 248
            G    P L  +   +   G P L            +G    P +  + G R LP P
Sbjct: 1286 GPPGLPGLRGDAGAKGEKGHPGL------------IGLIGPPGEQGEKGDRGLPGP 1329



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/192 (30%), Positives = 72/192 (37%), Gaps = 24/192 (12%)

Query: 25   PCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRP-LRARPGCRPR 83
            P    GP  + GP    G LPG+    G R  A   A PPG +G    P LR   G +  
Sbjct: 1245 PVGPAGPAGKPGPDGLRG-LPGSVGQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302

Query: 84   RPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSP-QPAPRPAPGRSSALALAGGAAPGVAR 142
            + HP    L   P     +  R  G P   GSP Q      PG S  +    G  PG+  
Sbjct: 1303 KGHPGLIGLIGPPGEQGEKGDR--GLPGPQGSPGQKGEMGIPGASGPIG--PGGPPGLPG 1358

Query: 143  AQRPGGSGGRSHPGGPGSPRG--GGTVGPGDRGPA--------------AADGGRPQRTV 186
               P G+ G + PGGP   +G  G    PG  G                + DG R  +  
Sbjct: 1359 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1418

Query: 187  RAAETRGAAAAP 198
             A  T GA  +P
Sbjct: 1419 EAIPTGGAPGSP 1430



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 50/155 (32%), Positives = 60/155 (38%), Gaps = 21/155 (13%)

Query: 31   PRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSV-----LRPLRARPGCRPRRP 85
            P ER  P T GG  PG +   GP  P P PA  PG  G+      + P   RPG  P+ P
Sbjct: 880  PGERGLPGTAGG--PGLKGNEGPSGP-PGPAGSPGERGAAGSGGPIGP-PGRPG--PQGP 933

Query: 86   HPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQR 145
              AA        +     + P G     G   P   P P     +A   G    V    +
Sbjct: 934  PGAAG------EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ 987

Query: 146  PGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG 179
             G  G +   G PG P   G +GP G  G A ADG
Sbjct: 988  KGTKGNKGEHGPPGPP---GPIGPVGQPGAAGADG 1019



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 54/203 (26%), Positives = 66/203 (32%), Gaps = 18/203 (8%)

Query: 25   PCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRR 84
            P  + GP+   G   P G+    R  PGP  P P     PG  G         P   P +
Sbjct: 816  PPGVVGPQGAAGETGPMGE----RGHPGPPGP-PGEQGLPGTAGKEGTKGDPGPPGAPGK 870

Query: 85   PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQ 144
              PA     LR     R      G P   G+  P+  P P  S     A G+   +    
Sbjct: 871  DGPAG----LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 926

Query: 145  RPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADG-GRPQRTVRAAETRGAAAAPP 199
            RPG  G     G  G P   G +GP    G +GP    G   P         +G    P 
Sbjct: 927  RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG 986

Query: 200  LTLEGPVQSHHGTPALTQGPQSP 222
                   +  HG P    GP  P
Sbjct: 987  QKGTKGNKGEHGPP----GPPGP 1005



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 49/161 (30%), Positives = 57/161 (35%), Gaps = 32/161 (19%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPL--PARPPGALGSVLRPLRARPGCR----PR 83
           GP    G R   G++ G R  PG   P  L  P  PPG  G         PG R    P+
Sbjct: 476 GPPGEDGERGDDGEI-GPRGLPGESGPRGLLGPKGPPGIPGP--------PGVRGMDGPQ 526

Query: 84  RPHPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVA 141
            P  +    P     P  +   PG  G P   G+  P     P     L       PG+ 
Sbjct: 527 GPKGSLG--PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGL-------PGM- 576

Query: 142 RAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGGR 181
               PG  G   HPG  G P   G  GP G +GP    G R
Sbjct: 577 ----PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 613



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 49/158 (31%), Positives = 55/158 (34%), Gaps = 21/158 (13%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP--PGALGSVLRPLRARPGCRPRRPHP 87
           GP+ R GP    G  PG     G      LP  P   G  GS+       PG        
Sbjct: 665 GPKGRTGPTGDPGP-PGLMGEKGKLGVPGLPGYPGRQGPKGSL-----GFPGFPGASGEK 718

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQR-- 145
            AR L  +     R  R P G        Q  PR A G+S A   +GG  P     +R  
Sbjct: 719 GARGLSGKSG--PRGERGPTG-----PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL 771

Query: 146 PGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAAADG 179
           PG  G    PG  G P   G  G    PG RG     G
Sbjct: 772 PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 809



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 47/166 (28%), Positives = 58/166 (34%), Gaps = 20/166 (12%)

Query: 30  GPRERHGPRTPGGQ--LPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHP 87
           GP    G R P G+  LPG+   PGP   + +     G+ G    P+ A    + +    
Sbjct: 313 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 372

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPG-------- 139
            AR     P  P     RPG  PL     QP      G S  L   G   P         
Sbjct: 373 QARLALRGPPGPMGYTGRPG--PLG----QPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 426

Query: 140 VARAQRPGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAAADGGR 181
             R  R G  G R  PG PG     G  G    PG++G     G +
Sbjct: 427 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 472



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 72/282 (25%), Positives = 88/282 (31%), Gaps = 61/282 (21%)

Query: 16   PRAASTTWVPCQI--CGPRERHGPRTPGGQLPGARRGPGP-------------------- 53
            P AA    VP +    GP  R G + P G LPG    PG                     
Sbjct: 934  PGAAGEKGVPGEKGPIGPTGRDGVQGPVG-LPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 992

Query: 54   RRPAPLPARPPGALGSVLRPLRA----RPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGF 109
             +    P  PPG +G V +P  A     PG R  + H  A+         TR    P G 
Sbjct: 993  NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK-----GDEGTRGFNGPPGP 1047

Query: 110  PLAWGSPQPA----------PRPAPGRSSALALAG--------GAAPGVARAQRPGGSGG 151
                G P P+          P   PG       AG        G   GV     PG  G 
Sbjct: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107

Query: 152  RSHPGGPGSPRGGGTVGP-GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHH 210
                G PG     G  GP G+RG     G       +  E        P   +GP + + 
Sbjct: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESG-------QPGEPGPPGPKGPTGDDGP-KGNP 1159

Query: 211  GTPALTQGPQSPRDGAQLGACTRPVDVRDSG--GRPLPPPDT 250
            G       P  P +G   G      D  + G  G+P  P  T
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1201



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 54/189 (28%), Positives = 66/189 (34%), Gaps = 46/189 (24%)

Query: 75  RARPGCRPRRPHPAARC---LPLRPHRPTRRHRR------PGGFPLAWGSP---QPAP-- 120
           R RP  + ++PH A R     P R HRP  +  +      P G     G P   +P    
Sbjct: 233 RERP--QNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLV 290

Query: 121 RPAPGRSSALALAGGAAPGVARAQRP-GGSGGRSHPGGPGSPRGGGTVGP---------- 169
              PG      L G   PG+     P G  G R  PG  G P   G  GP          
Sbjct: 291 EGPPGPEGPAGLIG--PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 348

Query: 170 -----GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTL-----EGPVQSHHGTPAL---- 215
                GD+GP  A     Q      + R A   PP  +      GP+    G+P L    
Sbjct: 349 FGSGGGDKGPVVA-AQEAQAQAILQQARLALRGPPGPMGYTGRPGPL-GQPGSPGLKGES 406

Query: 216 -TQGPQSPR 223
              GPQ PR
Sbjct: 407 GDLGPQGPR 415



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 21/168 (12%)

Query: 30  GPRERHGPRTPGGQL-PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPH-P 87
           G R   GP+ P G L P    GP  ++  P     PG  G++       P  +P  P  P
Sbjct: 518 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 577

Query: 88  AARCLPLRPHRP----TRRHRRPGG--FPLAWGSPQPAPRPAPGRSSALALAGGAA---- 137
            +   P  P +     T+ ++ P G   PL +    P PR   G      L G       
Sbjct: 578 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY----PGPRGVKGVDGIRGLKGHKGEKGE 633

Query: 138 ---PGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRP 182
              PG       G  G R   G PGS    G  GP  R     D G P
Sbjct: 634 DGFPGFKGDI--GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 679



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 47/157 (29%), Positives = 54/157 (34%), Gaps = 28/157 (17%)

Query: 37  PRTPGGQLPGARRGP-GPRRPAPLPARPPGALG-------SVLRPLRARPGCRPRRPHPA 88
           P +PG +      GP GPR P  L   PPG  G          R +   PG +  R    
Sbjct: 397 PGSPGLKGESGDLGPQGPRGPQGLTG-PPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 455

Query: 89  ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAP-GVARAQRPG 147
              LP       + HR   G   A G P P     PG        G   P G+     P 
Sbjct: 456 LPGLP-----GEKGHRGDTG---AQGLPGP-----PGEDGERGDDGEIGPRGLPGESGPR 502

Query: 148 GS-GGRSHPGGPGSPRGGGTVGP----GDRGPAAADG 179
           G  G +  PG PG P   G  GP    G  GP    G
Sbjct: 503 GLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 539



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 48/175 (27%), Positives = 60/175 (34%), Gaps = 25/175 (14%)

Query: 30  GPRERHGPR----TPGGQ-LPGARRGPGP---RRPAPLPARP--PGALGSVLRPLRARPG 79
           GP+   GP     TPG Q LPG +   GP   + P   P  P  PG+ G    P +  P 
Sbjct: 533 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 592

Query: 80  CRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGG---- 135
                  P+    PL    P       G   L     +      PG    + + G     
Sbjct: 593 GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 652

Query: 136 AAPGVARAQRPGGSGGRSHPGG-PGSPRGGGTVG----------PGDRGPAAADG 179
             PG      P G  GR+ P G PG P   G  G          PG +GP  + G
Sbjct: 653 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 707


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 73/239 (30%), Positives = 90/239 (37%), Gaps = 27/239 (11%)

Query: 36   GPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRP-LRARPGCRPRRPHPAARCLP- 93
            GP  P G  P   RGP     A  P  PPG +G++  P  +  PG       P  +  P 
Sbjct: 1174 GPMGPPG--PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG---ESGSPGIQGEPG 1228

Query: 94   LRPHRPTRRHRRPGGFPLAWGSPQP-------APRPAPGRSSALALAGGAAPGVARAQ-- 144
            ++  R  R  +   G P   G P P        P+  PG        G    G  R Q  
Sbjct: 1229 VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDG 1288

Query: 145  RPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADGGRPQRTVRAAE-TRGAAAAPP 199
              G  G    PG PGSP   G  GP    G RGPA + G   ++  + A+   GA  AP 
Sbjct: 1289 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1348

Query: 200  LTLEGPVQSHHGTPALTQGPQSPRD-GAQLGACTRPVDVRDSG-GRPLPPPDTLASAGD 256
             T  GPV      PA   GP   R     +G   RP     +G   P+ PP      GD
Sbjct: 1349 KT--GPVGP--AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1403



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 68/236 (28%), Positives = 81/236 (34%), Gaps = 47/236 (19%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPRRPA--PLPARPPGALGSVLRPLRARPGCRPRRPHP 87
            GPR   G +   GQ PG    PGP+ P     P   PG +G             P  P P
Sbjct: 1231 GPRGERGEKGESGQ-PGEPGPPGPKGPTGDDGPKGNPGPVGF------------PGDPGP 1277

Query: 88   AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGA-APGVARAQRP 146
                 P R     +  R   G P   GSP P     P     L   G A +PG     R 
Sbjct: 1278 PGEGGP-RGQDGAKGDRGEDGEPGQPGSPGPTGENGP--PGPLGKRGPAGSPG--SEGRQ 1332

Query: 147  GGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG-----------GRPQRTVRAAETR-- 192
            GG G +  PG  G+P   G VGP G  G    DG           GRP  T +A      
Sbjct: 1333 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1392

Query: 193  GAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPP 248
            G    P L  +   +   G P L            +G    P +  + G R LP P
Sbjct: 1393 GPPGLPGLRGDAGAKGEKGHPGL------------IGLIGPPGEQGEKGDRGLPGP 1436



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/192 (30%), Positives = 72/192 (37%), Gaps = 24/192 (12%)

Query: 25   PCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRP-LRARPGCRPR 83
            P    GP  + GP    G LPG+    G R  A   A PPG +G    P LR   G +  
Sbjct: 1352 PVGPAGPAGKPGPDGLRG-LPGSVGQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1409

Query: 84   RPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSP-QPAPRPAPGRSSALALAGGAAPGVAR 142
            + HP    L   P     +  R  G P   GSP Q      PG S  +    G  PG+  
Sbjct: 1410 KGHPGLIGLIGPPGEQGEKGDR--GLPGPQGSPGQKGEMGIPGASGPIG--PGGPPGLPG 1465

Query: 143  AQRPGGSGGRSHPGGPGSPRG--GGTVGPGDRGPA--------------AADGGRPQRTV 186
               P G+ G + PGGP   +G  G    PG  G                + DG R  +  
Sbjct: 1466 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1525

Query: 187  RAAETRGAAAAP 198
             A  T GA  +P
Sbjct: 1526 EAIPTGGAPGSP 1537



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 50/155 (32%), Positives = 60/155 (38%), Gaps = 21/155 (13%)

Query: 31   PRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSV-----LRPLRARPGCRPRRP 85
            P ER  P T GG  PG +   GP  P P PA  PG  G+      + P   RPG  P+ P
Sbjct: 987  PGERGLPGTAGG--PGLKGNEGPSGP-PGPAGSPGERGAAGSGGPIGP-PGRPG--PQGP 1040

Query: 86   HPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQR 145
              AA        +     + P G     G   P   P P     +A   G    V    +
Sbjct: 1041 PGAAG------EKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ 1094

Query: 146  PGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADG 179
             G  G +   G PG P   G +GP G  G A ADG
Sbjct: 1095 KGTKGNKGEHGPPGPP---GPIGPVGQPGAAGADG 1126



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 54/203 (26%), Positives = 66/203 (32%), Gaps = 18/203 (8%)

Query: 25   PCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRR 84
            P  + GP+   G   P G+    R  PGP  P P     PG  G         P   P +
Sbjct: 923  PPGVVGPQGAAGETGPMGE----RGHPGPPGP-PGEQGLPGTAGKEGTKGDPGPPGAPGK 977

Query: 85   PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQ 144
              PA     LR     R      G P   G+  P+  P P  S     A G+   +    
Sbjct: 978  DGPAG----LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 1033

Query: 145  RPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADG-GRPQRTVRAAETRGAAAAPP 199
            RPG  G     G  G P   G +GP    G +GP    G   P         +G    P 
Sbjct: 1034 RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG 1093

Query: 200  LTLEGPVQSHHGTPALTQGPQSP 222
                   +  HG P    GP  P
Sbjct: 1094 QKGTKGNKGEHGPP----GPPGP 1112



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 49/161 (30%), Positives = 57/161 (35%), Gaps = 32/161 (19%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPL--PARPPGALGSVLRPLRARPGCR----PR 83
           GP    G R   G++ G R  PG   P  L  P  PPG  G         PG R    P+
Sbjct: 583 GPPGEDGERGDDGEI-GPRGLPGESGPRGLLGPKGPPGIPGP--------PGVRGMDGPQ 633

Query: 84  RPHPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVA 141
            P  +    P     P  +   PG  G P   G+  P     P     L       PG+ 
Sbjct: 634 GPKGSLG--PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGL-------PGM- 683

Query: 142 RAQRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGGR 181
               PG  G   HPG  G P   G  GP G +GP    G R
Sbjct: 684 ----PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 49/158 (31%), Positives = 55/158 (34%), Gaps = 21/158 (13%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARP--PGALGSVLRPLRARPGCRPRRPHP 87
           GP+ R GP    G  PG     G      LP  P   G  GS+       PG        
Sbjct: 772 GPKGRTGPTGDPGP-PGLMGEKGKLGVPGLPGYPGRQGPKGSL-----GFPGFPGASGEK 825

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQR-- 145
            AR L  +     R  R P G        Q  PR A G+S A   +GG  P     +R  
Sbjct: 826 GARGLSGKSG--PRGERGPTG-----PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL 878

Query: 146 PGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAAADG 179
           PG  G    PG  G P   G  G    PG RG     G
Sbjct: 879 PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 916



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 47/166 (28%), Positives = 58/166 (34%), Gaps = 20/166 (12%)

Query: 30  GPRERHGPRTPGGQ--LPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHP 87
           GP    G R P G+  LPG+   PGP   + +     G+ G    P+ A    + +    
Sbjct: 420 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 479

Query: 88  AARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPG-------- 139
            AR     P  P     RPG  PL     QP      G S  L   G   P         
Sbjct: 480 QARLALRGPPGPMGYTGRPG--PLG----QPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 533

Query: 140 VARAQRPGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAAADGGR 181
             R  R G  G R  PG PG     G  G    PG++G     G +
Sbjct: 534 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 579



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 72/282 (25%), Positives = 88/282 (31%), Gaps = 61/282 (21%)

Query: 16   PRAASTTWVPCQI--CGPRERHGPRTPGGQLPGARRGPGP-------------------- 53
            P AA    VP +    GP  R G + P G LPG    PG                     
Sbjct: 1041 PGAAGEKGVPGEKGPIGPTGRDGVQGPVG-LPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1099

Query: 54   RRPAPLPARPPGALGSVLRPLRA----RPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGF 109
             +    P  PPG +G V +P  A     PG R  + H  A+         TR    P G 
Sbjct: 1100 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK-----GDEGTRGFNGPPGP 1154

Query: 110  PLAWGSPQPA----------PRPAPGRSSALALAG--------GAAPGVARAQRPGGSGG 151
                G P P+          P   PG       AG        G   GV     PG  G 
Sbjct: 1155 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1214

Query: 152  RSHPGGPGSPRGGGTVGP-GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHH 210
                G PG     G  GP G+RG     G       +  E        P   +GP + + 
Sbjct: 1215 PGESGSPGIQGEPGVKGPRGERGEKGESG-------QPGEPGPPGPKGPTGDDGP-KGNP 1266

Query: 211  GTPALTQGPQSPRDGAQLGACTRPVDVRDSG--GRPLPPPDT 250
            G       P  P +G   G      D  + G  G+P  P  T
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1308



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 21/168 (12%)

Query: 30  GPRERHGPRTPGGQL-PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPH-P 87
           G R   GP+ P G L P    GP  ++  P     PG  G++       P  +P  P  P
Sbjct: 625 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 684

Query: 88  AARCLPLRPHRP----TRRHRRPGG--FPLAWGSPQPAPRPAPGRSSALALAGGAA---- 137
            +   P  P +     T+ ++ P G   PL +    P PR   G      L G       
Sbjct: 685 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY----PGPRGVKGVDGIRGLKGHKGEKGE 740

Query: 138 ---PGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRP 182
              PG       G  G R   G PGS    G  GP  R     D G P
Sbjct: 741 DGFPGFKGDI--GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 786



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 37/126 (29%), Positives = 43/126 (34%), Gaps = 30/126 (23%)

Query: 124 PGRSSALALAGGAAPGVARAQRP-GGSGGRSHPGGPGSPRGGGTVGP------------- 169
           PG      L G   PG+     P G  G R  PG  G P   G  GP             
Sbjct: 401 PGPEGPAGLIG--PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGS 458

Query: 170 --GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTL-----EGPVQSHHGTPAL-----TQ 217
             GD+GP  A     Q      + R A   PP  +      GP+    G+P L       
Sbjct: 459 GGGDKGPVVA-AQEAQAQAILQQARLALRGPPGPMGYTGRPGPL-GQPGSPGLKGESGDL 516

Query: 218 GPQSPR 223
           GPQ PR
Sbjct: 517 GPQGPR 522



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 47/157 (29%), Positives = 54/157 (34%), Gaps = 28/157 (17%)

Query: 37  PRTPGGQLPGARRGP-GPRRPAPLPARPPGALG-------SVLRPLRARPGCRPRRPHPA 88
           P +PG +      GP GPR P  L   PPG  G          R +   PG +  R    
Sbjct: 504 PGSPGLKGESGDLGPQGPRGPQGLTG-PPGKAGRRGRAGADGARGMPGDPGVKGDRGFDG 562

Query: 89  ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAP-GVARAQRPG 147
              LP       + HR   G   A G P P     PG        G   P G+     P 
Sbjct: 563 LPGLP-----GEKGHRGDTG---AQGLPGP-----PGEDGERGDDGEIGPRGLPGESGPR 609

Query: 148 GS-GGRSHPGGPGSPRGGGTVGP----GDRGPAAADG 179
           G  G +  PG PG P   G  GP    G  GP    G
Sbjct: 610 GLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 646



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 48/175 (27%), Positives = 60/175 (34%), Gaps = 25/175 (14%)

Query: 30  GPRERHGPR----TPGGQ-LPGARRGPGP---RRPAPLPARP--PGALGSVLRPLRARPG 79
           GP+   GP     TPG Q LPG +   GP   + P   P  P  PG+ G    P +  P 
Sbjct: 640 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 699

Query: 80  CRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGG---- 135
                  P+    PL    P       G   L     +      PG    + + G     
Sbjct: 700 GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 759

Query: 136 AAPGVARAQRPGGSGGRSHPGG-PGSPRGGGTVG----------PGDRGPAAADG 179
             PG      P G  GR+ P G PG P   G  G          PG +GP  + G
Sbjct: 760 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG 814


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 79/255 (30%), Positives = 90/255 (35%), Gaps = 49/255 (19%)

Query: 30  GPRE-RHGPRTPGGQLPGARRGPG----PRRPAPLPARPPG-----ALGSVLR--PLRAR 77
           GP+  +H P  PGG +PG   GPG    PR   P P    G       G  +R  P+R  
Sbjct: 636 GPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGG 695

Query: 78  PGCRPRRPHPAARCL-------PLRPHRPTRRHRRPGGFPLAWGSPQPAP------RPAP 124
           PG  P   H             P  P R  R  R  GG P   G P          RP  
Sbjct: 696 PGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHE 755

Query: 125 GRSSALALAGGAAPGVARAQRPGG---SGGRSHPGGPGSPRGGG----TVGPGDRGPAAA 177
           G    +  + G  P     + PGG   SG R H G  GS  GGG      GPG  G +  
Sbjct: 756 GPGGGMGNSSGHRPH----EGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG-GISGG 810

Query: 178 DGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGA--CTRPV 235
            G RP          G    P    EGP  S  G+     G   P +G   G     RP 
Sbjct: 811 SGHRPHEGPGGGMGAGGGHRPH---EGPGGSMGGS-----GGHRPHEGPGHGGPHGHRPH 862

Query: 236 DVRDSGGRPL--PPP 248
           DV    G     PPP
Sbjct: 863 DVPGHRGHDHRGPPP 877



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 56/181 (30%), Positives = 59/181 (32%), Gaps = 60/181 (33%)

Query: 24  VPCQICGPRERHGPRTPGGQLPGARRG-----PGPRRPAPLPARPPGALGSVLRPLRARP 78
           VP  + GP        PGG  PG  +G     PGP  P P P   PG  G V        
Sbjct: 615 VPHGLLGPGPIANGFPPGG--PGGPKGMQHFPPGPGGPMPGPHGGPG--GPV-------- 662

Query: 79  GCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAP 138
           G R   P P  R                GG P  W  P    R  P R       GG  P
Sbjct: 663 GPRLLGPPPPPR----------------GGDPF-WDGPGDPMRGGPMR-------GGPGP 698

Query: 139 GVARAQR-PGGSGGRSHP---------------GGPGSPR---GGGTVGPGDRGPAAADG 179
           G     R  GG GG   P               GGP + R   GGG VG G   P    G
Sbjct: 699 GPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPG 758

Query: 180 G 180
           G
Sbjct: 759 G 759



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 35/116 (30%), Positives = 37/116 (31%), Gaps = 19/116 (16%)

Query: 146 PGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGP 205
           PG       PGGPG P+G     PG  GP     G P          G    P L   GP
Sbjct: 622 PGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGP----------GGPVGPRLL--GP 669

Query: 206 VQSHHGTPALTQGPQSPRDGAQLGACTRPVD---VRDSGGR----PLPPPDTLASA 254
                G      GP  P  G  +     P      R  GGR    P PPP     A
Sbjct: 670 PPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGA 725


>gi|21955170 single stranded DNA binding protein 3 isoform a [Homo
           sapiens]
          Length = 388

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 58/223 (26%), Positives = 81/223 (36%), Gaps = 32/223 (14%)

Query: 31  PRERHGPRTP---GGQLPGARRGPGPRRPAPL-PARPPGA--LGSVLRPLRARPGCRPRR 84
           PR   GPR P   G Q PG   G  P  P  + P R  G   +G  ++ +    G  P  
Sbjct: 154 PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG 213

Query: 85  PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALA----------G 134
           P P      +RP   +     PG   +  G+ +P P P    S   + +          G
Sbjct: 214 PGPQNYGSGMRPPPNSLGPAMPG-INMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 272

Query: 135 GAAPGVARAQRPGGSGGRS-------HPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVR 187
           G  PG      P  S   S       +P  PG  R    +GPG  GP    GG     + 
Sbjct: 273 GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMN 332

Query: 188 AAETRGAAAAPPLTLEG-PVQSHHGTPALTQGPQSPRDGAQLG 229
            +   G        ++G P  S +    ++  P +PRD  +LG
Sbjct: 333 GSLGSG-------DIDGLPKNSPNNISGISNPPGTPRDDGELG 368


>gi|58218981 single stranded DNA binding protein 3 isoform c [Homo
           sapiens]
          Length = 361

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 58/223 (26%), Positives = 81/223 (36%), Gaps = 32/223 (14%)

Query: 31  PRERHGPRTP---GGQLPGARRGPGPRRPAPL-PARPPGA--LGSVLRPLRARPGCRPRR 84
           PR   GPR P   G Q PG   G  P  P  + P R  G   +G  ++ +    G  P  
Sbjct: 127 PRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMG 186

Query: 85  PHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALA----------G 134
           P P      +RP   +     PG   +  G+ +P P P    S   + +          G
Sbjct: 187 PGPQNYGSGMRPPPNSLGPAMPG-INMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGG 245

Query: 135 GAAPGVARAQRPGGSGGRS-------HPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVR 187
           G  PG      P  S   S       +P  PG  R    +GPG  GP    GG     + 
Sbjct: 246 GGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMN 305

Query: 188 AAETRGAAAAPPLTLEG-PVQSHHGTPALTQGPQSPRDGAQLG 229
            +   G        ++G P  S +    ++  P +PRD  +LG
Sbjct: 306 GSLGSG-------DIDGLPKNSPNNISGISNPPGTPRDDGELG 341


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 55/200 (27%), Positives = 66/200 (33%), Gaps = 21/200 (10%)

Query: 50  GPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGF 109
           GPGP +  P P  PP        P + +    P++P P        PH+P          
Sbjct: 48  GPGPGQSGPKPPIPPPP------PHQQQQQPPPQQPPPQQP----PPHQPPPH------- 90

Query: 110 PLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP 169
           P      QP P P       +A   G APGV  A     S   + P   G+P G G  GP
Sbjct: 91  PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP-GP 149

Query: 170 GDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGP-QSPRDGAQL 228
               P A     P        + G    PP    GP       P    GP Q P  G   
Sbjct: 150 TPTPPPAVTSAPPGAPPPTPPSSGVPTTPP-QAGGPPPPPAAVPGPGPGPKQGPGPGGPK 208

Query: 229 GACTRPVDVRDSGGRPLPPP 248
           G    P   +  GG  L  P
Sbjct: 209 GG-KMPGGPKPGGGPGLSTP 227



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 48/170 (28%), Positives = 59/170 (34%), Gaps = 42/170 (24%)

Query: 37  PRTP--GGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPL 94
           P TP   G  PG+  GP P  P  + + PPGA                  P P +  +P 
Sbjct: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGA----------------PPPTPPSSGVPT 176

Query: 95  RPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSH 154
            P +       P   P     P P P+  PG        GG  PG     +PGG  G S 
Sbjct: 177 TPPQAGGPPPPPAAVP----GPGPGPKQGPGPGGP---KGGKMPG---GPKPGGGPGLST 226

Query: 155 PGGP--------GSPRGGGTVGP------GDRGPAAADGGRPQRTVRAAE 190
           PGG         G PRGG    P          P    GGR +  +  +E
Sbjct: 227 PGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSE 276



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 46/161 (28%), Positives = 54/161 (33%), Gaps = 19/161 (11%)

Query: 31  PRERHGPRTP--GGQLPGARRGPGPR-----RPAPLPARPPGALGSVLRPLRARPGCRPR 83
           P ++  P  P      P   +GPGP       P    + PP    +   P  + PG  P 
Sbjct: 93  PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPT 152

Query: 84  RPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARA 143
            P PA    P     PT         P   G P P P   PG            PG  + 
Sbjct: 153 PP-PAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG----------PGPGPKQG 201

Query: 144 QRPGGSGGRSHPGGPGSPRGGGTVGPGDR-GPAAADGGRPQ 183
             PGG  G   PGGP    G G   PG    P    GG P+
Sbjct: 202 PGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPR 242



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 5/89 (5%)

Query: 126 RSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRT 185
           R   + + GG A  +     P GSGG+  P   G    G    PG   P A   G    +
Sbjct: 606 RERDMRMGGGGAMNMGD---PYGSGGQKFPPLGGGGGIGYEANPGV--PPATMSGSMMGS 660

Query: 186 VRAAETRGAAAAPPLTLEGPVQSHHGTPA 214
               E  G   A P+  +GP     GTPA
Sbjct: 661 DMRTERFGQGGAGPVGGQGPRGMGPGTPA 689



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 35/132 (26%), Positives = 45/132 (34%), Gaps = 11/132 (8%)

Query: 134 GGAAPGVARAQRPGGSGG----RSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAA 189
           GG   G  R    GG GG    RS P G G  +  G +GPG  G +      P       
Sbjct: 10  GGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGP-GQSGPKPPIPPPPPHQQ 68

Query: 190 ETRGAAAAPPLTLEGPVQ--SHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRP--- 244
           + +     PP     P Q   H       Q P  P+D ++      P      G  P   
Sbjct: 69  QQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPAS 128

Query: 245 -LPPPDTLASAG 255
              PP T  ++G
Sbjct: 129 SSAPPATPPTSG 140


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 76/281 (27%), Positives = 91/281 (32%), Gaps = 81/281 (28%)

Query: 30  GPRERHGPRTPGGQ--------LPGARRG------PGPRRPAPLPAR--------PPGAL 67
           GP  + GP  P GQ         PGAR        PGP+  A  P +        PPGA+
Sbjct: 548 GPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAV 607

Query: 68  GSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA---- 123
           G   +   A     P    PA            R  + P G P   G P PA  P     
Sbjct: 608 GPAGKDGEAGAQGPPGPAGPAGE----------RGEQGPAGSPGFQGLPGPAGPPGEAGK 657

Query: 124 PGRSSALALAGGAAPGVARAQR-----------------------PGGSGGRSHPGGPGS 160
           PG        G   P  AR +R                       PG  G +   G PG+
Sbjct: 658 PGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717

Query: 161 PRGGGTVG----PGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALT 216
           P   G  G    PG+RG A   G +  R    A  +GA  +P            G   LT
Sbjct: 718 PGSQGAPGLQGMPGERGAAGLPGPKGDR--GDAGPKGADGSP---------GKDGVRGLT 766

Query: 217 QGPQSPRDGAQLGACTRPVDVRDSG-GRPLPPPDTLASAGD 256
            GP  P      G    P D  +SG   P  P     + GD
Sbjct: 767 -GPIGPP-----GPAGAPGDKGESGPSGPAGPTGARGAPGD 801



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 58/166 (34%), Positives = 63/166 (37%), Gaps = 25/166 (15%)

Query: 30   GPRERHGPRTPGGQLPGARRGPGPRRPAPL--------PARPPGALGSVLRPLRARPGCR 81
            G R   GP  P G  PGA   PGP  PA          PA P G +G    P+ AR    
Sbjct: 1034 GDRGETGPAGPPGA-PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVG----PVGARGPAG 1088

Query: 82   PRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAP-GRSSALALAGGAAPGV 140
            P+ P         +  R  + HR   GF    G P P   P   G S A   AG   P  
Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHR---GFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPP- 1144

Query: 141  ARAQRPGGSGGRSHPG--GPGSPRG----GGTVG-PGDRGPAAADG 179
              A  PG  G    PG  GP  PRG     G VG PG  GP    G
Sbjct: 1145 GSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPG 1190



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 63/197 (31%), Positives = 68/197 (34%), Gaps = 27/197 (13%)

Query: 31  PRERHGPRTPGGQ-LPGARRGPGPRRPAPLPARP-PGALGSVLRPLRARPGCRPRRPHPA 88
           P E   P   G + LPG R  PG   P P  AR   GA G+   P    P   P  P   
Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGA--PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349

Query: 89  ARCLPLRPHRPTRRHRRPGGFPLAWGSPQPA----PRPAPGRSSALALAGG-AAPGVARA 143
                  P  P R    P G     G P PA    P   PG        G   APG+A A
Sbjct: 350 GAKGEAGPQGP-RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408

Query: 144 QRPGGSGGRSHPGGPGSPRG--------------GGTVGPGDRGPAAADGGRPQRTVRAA 189
               G+ G S P GPG P G              G T   G+ GP    G  P       
Sbjct: 409 PGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG--PPGPAGEE 466

Query: 190 ETRGAAAAP-PLTLEGP 205
             RGA   P P  L GP
Sbjct: 467 GKRGARGEPGPTGLPGP 483



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 68/209 (32%), Positives = 76/209 (36%), Gaps = 38/209 (18%)

Query: 30   GPRERHGPR-------TPGGQLPGARRG-PGPRRPAPLPARPPGALGSVLRPLRARPGCR 81
            GPR   GP         PG   P   +G PG   PA  P  P     +  R +   PG R
Sbjct: 908  GPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQR 967

Query: 82   PRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA----PGRSSALALAGGAA 137
              R  P    LP     P ++   P G     G P P   P     PG S     A GA 
Sbjct: 968  GERGFPG---LPGPSGEPGKQG--PSGASGERGPPGPMGPPGLAGPPGESGREG-APGAE 1021

Query: 138  PGVARAQRPGGSGGRSHPGG---PGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGA 194
                R   PG  G R   G    PG+P  G    PG  GPA   G R        ET  A
Sbjct: 1022 GSPGRDGSPGAKGDRGETGPAGPPGAP--GAPGAPGPVGPAGKSGDR-------GETGPA 1072

Query: 195  AAAPPLTLEGPVQSHHGTPALTQGPQSPR 223
              A P+   GPV +    PA   GPQ PR
Sbjct: 1073 GPAGPV---GPVGAR--GPA---GPQGPR 1093



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 81/293 (27%), Positives = 94/293 (32%), Gaps = 66/293 (22%)

Query: 11  CP--CQVPRAASTTWV--PCQICGPRERHGPRTPGGQ--LPGARRGPGPRRPAPLPARPP 64
           CP   + P    TT V  P    GPR   GP  P G+  +PG    PGP  P P P  PP
Sbjct: 95  CPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGP-PGPPGPP 153

Query: 65  GALGSVL--------------------------RPLRARPGCR--------PRRPHPAAR 90
           G  G+                            R L   PG          P  P     
Sbjct: 154 GLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGA 213

Query: 91  CLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQR----- 145
             P+ P  P     + G    A    +P  R  PG   A  L G A     +  R     
Sbjct: 214 SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGL 273

Query: 146 ------PGGSGGRSHPGGPGSPRGGGTVG----PGDRGPAAADGGRPQRTVRAAETRGAA 195
                  G +G +  PG PG     G +G    PG+RG   A G    R    A   GAA
Sbjct: 274 DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGA--TGAA 331

Query: 196 AAP-PLTLEGPVQSHHGTPALTQ-GPQSPRDGAQLGACTRPVDVRDSGGRPLP 246
             P P    GP        A  + GPQ PR          P  VR   G P P
Sbjct: 332 GPPGPTGPAGPPGFPGAVGAKGEAGPQGPR------GSEGPQGVRGEPGPPGP 378



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 76/261 (29%), Positives = 86/261 (32%), Gaps = 47/261 (18%)

Query: 30  GPRERHGPRTPGGQ-----------LPGARRGPGPR-RPAPLPAR-PPGALGSVLRPLRA 76
           G R   GP+ PGG             PG++   G +  P P+  + PPG  G        
Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE------- 465

Query: 77  RPGCRPRRPHPAARCLPLRPHRPTRRHRRPG--GFPLAWGSPQPAPRPAPGRSSALALAG 134
             G R  R  P    LP     P      PG  GFP A G   P   PA  R S      
Sbjct: 466 -EGKRGARGEPGPTGLP----GPPGERGGPGSRGFPGADGVAGPKG-PAGERGSPGPAGP 519

Query: 135 GAAPGVA-RAQRPGGSGGRSHPGGPGSPRGGGTVGP-------GDRGPAAADGGRPQRTV 186
             +PG A R    G  G +   G PGSP   G  GP       G  GP    G R Q  V
Sbjct: 520 KGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGV 579

Query: 187 RA-AETRGAAAAPPLTLEGPVQSHHGT--------PALTQGPQSPRDGAQLGACTRPVDV 237
                 +GAA  P    E  V    G          A  QGP  P   A       P   
Sbjct: 580 MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGS 639

Query: 238 RDSGGRPLP--PPDTLASAGD 256
               G P P  PP      G+
Sbjct: 640 PGFQGLPGPAGPPGEAGKPGE 660



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 59/177 (33%), Positives = 65/177 (36%), Gaps = 31/177 (17%)

Query: 25  PCQICGPRERHGPRTPGGQL-----PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPG 79
           P    G +   GP  P G       PG R  PGP  PA   A PPGA G      +  PG
Sbjct: 774 PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF-AGPPGADGQP--GAKGEPG 830

Query: 80  CRPRR-----PHPAARCLPLRPHRPTRRHRRPG--------GFPLAWGSPQPAPRPAPGR 126
               +     P PA    P  P  P      PG        G P A G P  A R  P  
Sbjct: 831 DAGAKGDAGPPGPAG---PAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887

Query: 127 SSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP----GDRGPAAADG 179
            S  A   G  PG   A + GG G R   G  G P   G  GP    G++G   ADG
Sbjct: 888 PSGNAGPPG-PPG--PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 64/222 (28%), Positives = 74/222 (33%), Gaps = 46/222 (20%)

Query: 30   GPRERHGPRTP-------GGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRP 82
            GP    GP  P       GG+ P    GP  R     P  PPG  G    P    P   P
Sbjct: 887  GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946

Query: 83   RRPHPAARCLPLRPHR-----PTRRHRRPGGFPLAWGSPQPAPRPA-------------P 124
              P P      +   R     P +R  R  GFP   G P P+  P              P
Sbjct: 947  GTPGPQG----IAGQRGVVGLPGQRGER--GFP---GLPGPSGEPGKQGPSGASGERGPP 997

Query: 125  GRSSALALAGGAAPGVA-RAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADG--GR 181
            G      LAG   PG + R   PG  G     G PG+    G  GP   GP  A G  G 
Sbjct: 998  GPMGPPGLAG--PPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA--GPPGAPGAPGA 1053

Query: 182  PQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPR 223
            P     A ++       P    GPV      P   +GP  P+
Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPV-----GPVGARGPAGPQ 1090



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 67/228 (29%), Positives = 77/228 (33%), Gaps = 49/228 (21%)

Query: 33   ERHGPRTPGGQLPGARRGP----GPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPA 88
            ER  P  PG      ++GP    G R P P P  PPG  G         PG   R   P 
Sbjct: 969  ERGFPGLPGPSGEPGKQGPSGASGERGP-PGPMGPPGLAGP--------PGESGREGAPG 1019

Query: 89   ARCLPLRPHRPTRRHRR----PGGFPLAWGSP-QPAPRPAPGRSSALALAGGAAP----- 138
            A   P R   P  +  R    P G P A G+P  P P    G+S      G A P     
Sbjct: 1020 AEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVG 1079

Query: 139  -----GVARAQRPGGSGGRSHPGG----------------PGSPRGGGTVGP-GDRGPAA 176
                 G A  Q P G  G +   G                PG P   G  GP G  GPA 
Sbjct: 1080 PVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAG 1139

Query: 177  ADGGRPQRTVRAAETRGAAAAP-PLTLEGP-VQSHHGTPALTQGPQSP 222
              G  P  +  A    G    P P+   GP  ++    P    GP  P
Sbjct: 1140 PRG--PPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGP 1185



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 67/228 (29%), Positives = 79/228 (34%), Gaps = 31/228 (13%)

Query: 37  PRTPGGQ-LPGARRGPGPRRPAPLP--------ARPPGALGSV----LRPLRARPGCRPR 83
           P  PG Q  PG +  PG R  A LP        A P GA GS     +R L    G    
Sbjct: 715 PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIG---- 770

Query: 84  RPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARA 143
            P PA          P+     P G   A G+P     P P   +  A   GA       
Sbjct: 771 PPGPAGAPGDKGESGPSG----PAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK 826

Query: 144 QRPGGSGGRSHPGGPGSPRGGGTVGP-GDRGPAAADGGRPQRTVRAAETRGAAA---APP 199
             PG +G +   G PG     G  GP G+ G   A G R       A     AA    PP
Sbjct: 827 GEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPP 886

Query: 200 LTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPP 247
                        PA  +G + PR   + G   RP +V    G P PP
Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGPR--GETGPAGRPGEV----GPPGPP 928


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 65/238 (27%), Positives = 75/238 (31%), Gaps = 47/238 (19%)

Query: 45  PGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGC----RPRRPHPAARCLPLRPHRPT 100
           P    G GP  PA      PGA        RARPG     RP  P P    +P  P  P 
Sbjct: 67  PAGAAGAGPAAPAE---GAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA 123

Query: 101 RRHRRPGGFPLAWGSPQPA-------PRPAPGR----SSALALAGGAAPGVARAQRPGGS 149
            + R P        +P PA       P PAP      +   ALA  A PG      PG  
Sbjct: 124 AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG 183

Query: 150 GGRSHPGGPGSPR--------------GGGTVGPGDRGPAA----ADGGRPQRTVRAAET 191
            G   P GPG+ +                  V   + GPAA         P   ++    
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243

Query: 192 RGAAAAP-PLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPP 248
            GAAA P P     P       PA    P  P           P  +    G P  PP
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP----------APATLARPPGHPAGPP 291



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 74/247 (29%), Positives = 88/247 (35%), Gaps = 53/247 (21%)

Query: 6   GSAQACPCQVPRAASTTWVPCQI-CGPRERHGPRT---PGGQLPGARRGPGPRRPAPLPA 61
           GSA +C   VP AA+    P     GP +  GP       G  PG   GPG   P P P 
Sbjct: 132 GSAGSC-APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG---PGPGPG 187

Query: 62  RP--PGALGSV--------------------------LRPL--RARPGCRPRRPHPAARC 91
           +P  PGA  ++                          L PL   A PG   + P      
Sbjct: 188 KPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAA 247

Query: 92  LPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPA-----PGRSSALALAGGAAPGVARAQRP 146
            P  P  P+         P A   P P P PA     PG  +    A  A P  A AQ  
Sbjct: 248 APPAPAAPSPPAAPAPAAPAA-APPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306

Query: 147 GGSGGRSHPG-GPGSPRG-GGTVGPGDRGPAAADGGR---PQRTVRAAETRGAAAAPPLT 201
           G +G    P    G P G  G  GPG    A A G +   P+R V+AA      AA  L 
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAA----PPAAQTLA 362

Query: 202 LEGPVQS 208
             GP  +
Sbjct: 363 ASGPAST 369



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 62/218 (28%), Positives = 75/218 (34%), Gaps = 20/218 (9%)

Query: 50  GPGPRRPAPLPARP------PGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRH 103
           GP    P P PA P      P  +G+   P  A P   P  P PAA      P  P    
Sbjct: 221 GPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS-PPAAPAPAAPAAAPPPPPPAPAT 279

Query: 104 -RRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPR 162
             RP G P   G P  AP   P  ++    + GAAP  A A   GG  G S   GPG+  
Sbjct: 280 LARPPGHPA--GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA--GGPAGVSGQPGPGAAA 335

Query: 163 GGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPL----TLEGPVQSHHGTPALTQG 218
                G     P       P      A +  A+ A  +    T++G + S    P    G
Sbjct: 336 AAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG 395

Query: 219 PQSPRDGAQLGACT----RPVDVRDSGGRPLPPPDTLA 252
             +       GA T    R      SG R    P  LA
Sbjct: 396 TPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 62/240 (25%), Positives = 78/240 (32%), Gaps = 45/240 (18%)

Query: 30  GPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAA 89
           G  +R GP +P  + P    GP P   A L   P G+ GS      A        P PA 
Sbjct: 100 GGPQRPGPPSP--RRPLVPAGPAP-PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG 156

Query: 90  RCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGR----SSALALAG---------GA 136
              P +P  P     R G  P     P P P P PG+     +A  L G          A
Sbjct: 157 ---PAKPAGPAALAARAG--PGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAA 211

Query: 137 APGVARAQ----------RPGGSG---------GRSHPGGPGSPRGGGTVGPGDRGPAAA 177
           AP V+             +P   G         G + P  P +P       P    PAAA
Sbjct: 212 APAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAP--SPPAAPAPAAPAAA 269

Query: 178 DGGRPQRTVRAAETRGAAAAPPL---TLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRP 234
               P      A   G  A PP     +  P  + +G  A      +P  G   G   +P
Sbjct: 270 PPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP 329



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 46/163 (28%), Positives = 53/163 (32%), Gaps = 13/163 (7%)

Query: 94  LRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRS 153
           L P  P  R    G       S  PA     G ++    A GAAP    A       GR+
Sbjct: 43  LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPA-------GRA 95

Query: 154 HPGGPGSPRGGGTVGPGDRGPAAADG-GRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGT 212
            PGG G  R G    P  R P    G   P   +R      A +  P+     V +  G 
Sbjct: 96  RPGGGGPQRPG---PPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAA--GP 150

Query: 213 PALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPPDTLASAG 255
                GP  P   A L A   P      G  P P P   A  G
Sbjct: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG 193



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 70/258 (27%), Positives = 87/258 (33%), Gaps = 66/258 (25%)

Query: 4   GMGSAQACPC---------QVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPG-- 52
           G G+A A P          +V +AA          GP         G  + GA   P   
Sbjct: 330 GPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAV 389

Query: 53  -PRRPAPLPARPPGALGSVLRPLRARP-----GCRPR-RPHPAARCLPLRPHRPT--RRH 103
            P  P      P GA G+V + L   P     G R    P   A  LP  P  PT  +  
Sbjct: 390 PPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449

Query: 104 RRPGGFPL----------------------AWGSPQP--APRPA-PGRSSALALAGGAAP 138
           + P G  L                      A   PQ   APRPA P  +  + ++   AP
Sbjct: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAP 509

Query: 139 G----------------VARAQ---RPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAA-D 178
           G                V++AQ   +P  +  RS PG       GG       G A A  
Sbjct: 510 GTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRS-PGVQPQLVLGGAAQTASLGTATAVQ 568

Query: 179 GGRPQRTVRAAETRGAAA 196
            G PQRTV  A T  +AA
Sbjct: 569 TGTPQRTVPGATTTSSAA 586


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.139    0.466 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,576,790
Number of Sequences: 37866
Number of extensions: 1466213
Number of successful extensions: 23351
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 505
Number of HSP's successfully gapped in prelim test: 2054
Number of HSP's that attempted gapping in prelim test: 10115
Number of HSP's gapped (non-prelim): 8229
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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