Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 11321585
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
(340 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 704 0.0
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 649 0.0
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 648 0.0
gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [H... 612 e-175
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 374 e-104
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 374 e-104
gi|32189425 WD repeat domain 69 [Homo sapiens] 132 6e-31
gi|16554629 WD repeat domain 5 [Homo sapiens] 119 5e-27
gi|16554627 WD repeat domain 5 [Homo sapiens] 119 5e-27
gi|23199987 WD repeat domain 5B [Homo sapiens] 117 1e-26
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 117 1e-26
gi|113865883 WD repeat domain 38 [Homo sapiens] 115 6e-26
gi|21071067 TBP-associated factor 5 [Homo sapiens] 114 1e-25
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 111 8e-25
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 106 3e-23
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 106 3e-23
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 106 3e-23
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 105 4e-23
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 105 4e-23
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 105 6e-23
gi|13376840 WD repeat domain 61 [Homo sapiens] 102 4e-22
gi|5174447 guanine nucleotide binding protein (G protein), beta ... 102 5e-22
gi|26665869 WD repeat domain 51B [Homo sapiens] 102 5e-22
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 102 6e-22
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 99 4e-21
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 98 1e-20
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 95 8e-20
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 95 1e-19
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 94 1e-19
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 92 7e-19
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 704 bits (1816), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA 60
MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA
Sbjct: 1 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA 60
Query: 61 MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI 120
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
Sbjct: 61 MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI 120
Query: 121 CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF 180
CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF
Sbjct: 121 CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF 180
Query: 181 TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA 240
TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
Sbjct: 181 TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA 240
Query: 241 FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL
Sbjct: 241 FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit
[Homo sapiens]
Length = 340
Score = 649 bits (1673), Expect = 0.0
Identities = 309/340 (90%), Positives = 326/340 (95%)
Query: 1 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA 60
MSEL+QLRQEAEQL+NQI+DARKAC DATL QIT+N+D VGRIQMRTRRTLRGHLAKIYA
Sbjct: 1 MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQMRTRRTLRGHLAKIYA 60
Query: 61 MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI 120
MHWG DSRLLVSASQDGKLIIWDSYTTNK+HAIPLRSSWVMTCAYAPSGNYVACGGLDNI
Sbjct: 61 MHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNI 120
Query: 121 CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF 180
CSIYNLKTREGNVRVSREL GHTGYLSCCRFLDD+QIVTSSGDTTCALWDIET QQTTTF
Sbjct: 121 CSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTF 180
Query: 181 TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA 240
TGH+GDVMSLSL+PD R FVSGACDAS+KLWD+R+GMCRQ+FTGH SDINA+ FFPNG A
Sbjct: 181 TGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYA 240
Query: 241 FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
FATGSDDATCRLFDLRADQEL+ YSHDNIICGITSV+FSKSGRLLLAGYDDFNCNVWD L
Sbjct: 241 FATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL 300
Query: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
K DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFL+IWN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
[Homo sapiens]
Length = 340
Score = 648 bits (1671), Expect = 0.0
Identities = 307/340 (90%), Positives = 323/340 (95%)
Query: 1 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA 60
MSEL+QLRQEAEQL+NQIRDARKAC D+TL+QIT +DPVGRIQMRTRRTLRGHLAKIYA
Sbjct: 1 MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGRIQMRTRRTLRGHLAKIYA 60
Query: 61 MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI 120
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN+VACGGLDNI
Sbjct: 61 MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNI 120
Query: 121 CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF 180
CSIY+LKTREGNVRVSREL GHTGYLSCCRFLDDNQI+TSSGDTTCALWDIETGQQT F
Sbjct: 121 CSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGF 180
Query: 181 TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA 240
GH+GDVMSLSLAPD R FVSGACDAS KLWDVR+ MCRQTF GHESDINA+ FFPNG A
Sbjct: 181 AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA 240
Query: 241 FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
F TGSDDATCRLFDLRADQEL+ YSHDNIICGITSV+FS+SGRLLLAGYDDFNCN+WDA+
Sbjct: 241 FTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
K DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [Homo
sapiens]
Length = 340
Score = 612 bits (1578), Expect = e-175
Identities = 283/340 (83%), Positives = 315/340 (92%)
Query: 1 MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA 60
M E++QLRQEAEQLK QI DARKACAD TL+++ + ++ VGR+QMRTRRTLRGHLAKIYA
Sbjct: 1 MGEMEQLRQEAEQLKKQIADARKACADVTLAELVSGLEVVGRVQMRTRRTLRGHLAKIYA 60
Query: 61 MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI 120
MHW TDS+LLVSASQDGKLI+WDSYTTNKVHAIPLRSSWVMTCAYAPSGN+VACGGLDN+
Sbjct: 61 MHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNM 120
Query: 121 CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF 180
CSIYNLK+REGNV+VSREL+ HTGYLSCCRFLDDN IVTSSGDTTCALWDIETGQQ T F
Sbjct: 121 CSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVF 180
Query: 181 TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA 240
GHTGD MSL+++PD LF+SGACDASAKLWDVREG CRQTFTGHESDINAICFFPNG A
Sbjct: 181 VGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEA 240
Query: 241 FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
TGSDDA+CRLFDLRADQEL+ +SH++IICGITSV+FS SGRLL AGYDDFNCNVWD++
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
K++R G+L+GHDNRVSCLGVT DGMAVATGSWDSFLKIWN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 374 bits (961), Expect = e-104
Identities = 180/341 (52%), Positives = 234/341 (68%), Gaps = 5/341 (1%)
Query: 4 LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHW 63
L L+ EAE LK ++ + R D L Q+ ++ +G+ M+TRRTL+GH K+ M W
Sbjct: 12 LASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDW 71
Query: 64 GTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSI 123
D R +VS+SQDGK+I+WDS+TTNK HA+ + +WVM CAYAPSG +ACGGLDN CS+
Sbjct: 72 CKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSV 131
Query: 124 YNLK--TREGNVRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTF 180
Y L E + +A HT YLS C F + D QI+T+SGD TCALWD+E+GQ +F
Sbjct: 132 YPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSF 191
Query: 181 TGHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNG 238
GH DV+ L LAP FVSG CD A +WD+R G C Q F HESDIN++ ++P+G
Sbjct: 192 HGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSG 251
Query: 239 NAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
+AFA+GSDDATCRL+DLRAD+E+ YS ++II G +SV FS SGRLL AGY+D+ NVWD
Sbjct: 252 DAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWD 311
Query: 299 ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
LK R +L GH+NRVS L V+ DG A +GSWD L++W
Sbjct: 312 VLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 62.4 bits (150), Expect = 6e-10
Identities = 50/215 (23%), Positives = 91/215 (42%), Gaps = 7/215 (3%)
Query: 133 VRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLS 191
++ R L GH + C + D + IV+SS D +WD T + T VM+ +
Sbjct: 53 MKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACA 112
Query: 192 LAPDTRLFVSGACDASAKLW----DVREGMC--RQTFTGHESDINAICFFPNGNAFATGS 245
AP G D ++ D E M +++ H + ++A F + T S
Sbjct: 113 YAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS 172
Query: 246 DDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA 305
D TC L+D+ + Q L ++ ++ S++G ++G D VWD
Sbjct: 173 GDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCV 232
Query: 306 GVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
H++ ++ + G A A+GS D+ ++++
Sbjct: 233 QAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 267
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 374 bits (961), Expect = e-104
Identities = 180/341 (52%), Positives = 234/341 (68%), Gaps = 5/341 (1%)
Query: 4 LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHW 63
L L+ EAE LK ++ + R D L Q+ ++ +G+ M+TRRTL+GH K+ M W
Sbjct: 54 LASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLKGHGNKVLCMDW 113
Query: 64 GTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSI 123
D R +VS+SQDGK+I+WDS+TTNK HA+ + +WVM CAYAPSG +ACGGLDN CS+
Sbjct: 114 CKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSV 173
Query: 124 YNLK--TREGNVRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTF 180
Y L E + +A HT YLS C F + D QI+T+SGD TCALWD+E+GQ +F
Sbjct: 174 YPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSF 233
Query: 181 TGHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNG 238
GH DV+ L LAP FVSG CD A +WD+R G C Q F HESDIN++ ++P+G
Sbjct: 234 HGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSG 293
Query: 239 NAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
+AFA+GSDDATCRL+DLRAD+E+ YS ++II G +SV FS SGRLL AGY+D+ NVWD
Sbjct: 294 DAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWD 353
Query: 299 ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
LK R +L GH+NRVS L V+ DG A +GSWD L++W
Sbjct: 354 VLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
Score = 62.4 bits (150), Expect = 6e-10
Identities = 50/215 (23%), Positives = 91/215 (42%), Gaps = 7/215 (3%)
Query: 133 VRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLS 191
++ R L GH + C + D + IV+SS D +WD T + T VM+ +
Sbjct: 95 MKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACA 154
Query: 192 LAPDTRLFVSGACDASAKLW----DVREGMC--RQTFTGHESDINAICFFPNGNAFATGS 245
AP G D ++ D E M +++ H + ++A F + T S
Sbjct: 155 YAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS 214
Query: 246 DDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA 305
D TC L+D+ + Q L ++ ++ S++G ++G D VWD
Sbjct: 215 GDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCV 274
Query: 306 GVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
H++ ++ + G A A+GS D+ ++++
Sbjct: 275 QAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 309
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 132 bits (331), Expect = 6e-31
Identities = 83/293 (28%), Positives = 130/293 (44%), Gaps = 10/293 (3%)
Query: 50 TLRGHLAKIYAMHWGTD-SRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
TL GH +YA+ + + + S D +W T H ++ ++ ++ P
Sbjct: 129 TLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 188
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIVTSSGDTTCA 167
VA G +D +++++ E L GH+ + F ++I+T S D T
Sbjct: 189 STLVATGSMDTTAKLWDIQNGEEVYT----LRGHSAEIISLSFNTSGDRIITGSFDHTVV 244
Query: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
+WD +TG++ GH ++ S S D L ++G+ D + KLWD G C T TGH+
Sbjct: 245 VWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDD 304
Query: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSFSKSGRLLL 286
+I CF G AT S D T R+F + + H+ I+ +SF+ G LL
Sbjct: 305 EILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEG---EISKISFNPQGNHLL 361
Query: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
G D +WDA VL GH + + G V TGS D+ +IW
Sbjct: 362 TGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 126 bits (317), Expect = 2e-29
Identities = 85/264 (32%), Positives = 129/264 (48%), Gaps = 33/264 (12%)
Query: 89 KVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN------LKTREGNVRVSRELAGH 142
K H +PL + A SG+ G D C +++ L T EG+ V +A +
Sbjct: 89 KAHILPLTN-----VALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 143 TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSG 202
Y ++I T S D TC LW +ETG+ TF GHT +++ LS P + L +G
Sbjct: 144 NPY--------GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATG 195
Query: 203 ACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELM 262
+ D +AKLWD++ G T GH ++I ++ F +G+ TGS D T ++D +++
Sbjct: 196 SMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKV- 254
Query: 263 TYSHDNIICG----ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV--S 316
NI+ G I+S SF+ L+L G D C +WDA L GHD+ + S
Sbjct: 255 -----NILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 317 CLGVTDDGMAVATGSWDSFLKIWN 340
C T G +AT S D +I++
Sbjct: 310 CFDYT--GKLIATASADGTARIFS 331
Score = 117 bits (293), Expect = 1e-26
Identities = 74/295 (25%), Positives = 136/295 (46%), Gaps = 10/295 (3%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYA-P 107
+ L+ H+ + + ++ S D +WD+ + +++ + + V A+ P
Sbjct: 86 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNP 145
Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTC 166
G+ +A G D C +++++T + GHT + C F + +V T S DTT
Sbjct: 146 YGDKIATGSFDKTCKLWSVETG----KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTA 201
Query: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
LWDI+ G++ T GH+ +++SLS ++G+ D + +WD G GH
Sbjct: 202 KLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHC 261
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSFSKSGRLL 285
++I++ F + + TGS D TC+L+D + + T + HD+ I F +G+L+
Sbjct: 262 AEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDD---EILDSCFDYTGKLI 318
Query: 286 LAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
D ++ A L GH+ +S + G + TGS D +IW+
Sbjct: 319 ATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 373
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 119 bits (297), Expect = 5e-27
Identities = 69/245 (28%), Positives = 118/245 (48%), Gaps = 9/245 (3%)
Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQIV 158
V + ++P+G ++A D + I+ + + + ++GH G D N +V
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAY----DGKFEKTISGHKLGISDVAWSSDSNLLV 103
Query: 159 TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMC 218
++S D T +WD+ +G+ T GH+ V + P + L VSG+ D S ++WDV+ G C
Sbjct: 104 SASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKC 163
Query: 219 RQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 278
+T H ++A+ F +G+ + S D CR++D + Q L T D+ ++ V F
Sbjct: 164 LKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDD-NPPVSFVKF 222
Query: 279 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV---TDDGMAVATGSWDSF 335
S +G+ +LA D +WD K GH N C+ G + +GS D+
Sbjct: 223 SPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNL 282
Query: 336 LKIWN 340
+ IWN
Sbjct: 283 VYIWN 287
Score = 106 bits (264), Expect = 3e-23
Identities = 66/226 (29%), Positives = 110/226 (48%), Gaps = 13/226 (5%)
Query: 41 GRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWV 100
G + +T+ GH I + W +DS LLVSAS D L IWD + + + S++V
Sbjct: 73 GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYV 132
Query: 101 MTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIVT 159
C + P N + G D I+++KT + + L H+ +S F D + IV+
Sbjct: 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTG----KCLKTLPAHSDPVSAVHFNRDGSLIVS 188
Query: 160 SSGDTTCALWDIETGQQTTTFTGHTGDVMS-LSLAPDTRLFVSGACDASAKLWDVREGMC 218
SS D C +WD +GQ T +S + +P+ + ++ D + KLWD +G C
Sbjct: 189 SSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKC 248
Query: 219 RQTFTGHESDINAICFFPN-----GNAFATGSDDATCRLFDLRADQ 259
+T+TGH+++ C F N G +GS+D +++L+ +
Sbjct: 249 LKTYTGHKNE--KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKE 292
Score = 103 bits (258), Expect = 2e-22
Identities = 73/295 (24%), Positives = 132/295 (44%), Gaps = 9/295 (3%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
TL GH + ++ + + L S+S D + IW +Y I + A++
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIVTSSGDTTCAL 168
N + D I+++ + + + L GH+ Y+ CC F N IV+ S D + +
Sbjct: 100 NLLVSASDDKTLKIWDVSSG----KCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRI 155
Query: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES- 227
WD++TG+ T H+ V ++ D L VS + D ++WD G C +T ++
Sbjct: 156 WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP 215
Query: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSFSKSGRLLL 286
++ + F PNG + D T +L+D + L TY+ H N I + G+ ++
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 339
+G +D +W+ + L GH + V + T++ +A A D +K+W
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 80.1 bits (196), Expect = 3e-15
Identities = 42/163 (25%), Positives = 77/163 (47%), Gaps = 4/163 (2%)
Query: 179 TFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNG 238
T GHT V S+ +P+ S + D K+W +G +T +GH+ I+ + + +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 239 NAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
N + SDD T +++D+ + + L T H N + +F+ L+++G D + +W
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNY---VFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 298 DALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
D L H + VS + DG + + S+D +IW+
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 199
Score = 60.5 bits (145), Expect = 2e-09
Identities = 44/170 (25%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHA-IPLRSSWVMTCAYAP 107
+TL H + A+H+ D L+VS+S DG IWD+ + + I + V ++P
Sbjct: 165 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSP 224
Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCC----RFLDDNQIVTSSGD 163
+G Y+ LDN +++ + + GH C IV+ S D
Sbjct: 225 NGKYILAATLDNTLKLWDYSKG----KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSED 280
Query: 164 TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC--DASAKLW 211
+W+++T + GHT V+S + P + S A D + KLW
Sbjct: 281 NLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 119 bits (297), Expect = 5e-27
Identities = 69/245 (28%), Positives = 118/245 (48%), Gaps = 9/245 (3%)
Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHT-GYLSCCRFLDDNQIV 158
V + ++P+G ++A D + I+ + + + ++GH G D N +V
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAY----DGKFEKTISGHKLGISDVAWSSDSNLLV 103
Query: 159 TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMC 218
++S D T +WD+ +G+ T GH+ V + P + L VSG+ D S ++WDV+ G C
Sbjct: 104 SASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKC 163
Query: 219 RQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 278
+T H ++A+ F +G+ + S D CR++D + Q L T D+ ++ V F
Sbjct: 164 LKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDD-NPPVSFVKF 222
Query: 279 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGV---TDDGMAVATGSWDSF 335
S +G+ +LA D +WD K GH N C+ G + +GS D+
Sbjct: 223 SPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNL 282
Query: 336 LKIWN 340
+ IWN
Sbjct: 283 VYIWN 287
Score = 106 bits (264), Expect = 3e-23
Identities = 66/226 (29%), Positives = 110/226 (48%), Gaps = 13/226 (5%)
Query: 41 GRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWV 100
G + +T+ GH I + W +DS LLVSAS D L IWD + + + S++V
Sbjct: 73 GAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYV 132
Query: 101 MTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIVT 159
C + P N + G D I+++KT + + L H+ +S F D + IV+
Sbjct: 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTG----KCLKTLPAHSDPVSAVHFNRDGSLIVS 188
Query: 160 SSGDTTCALWDIETGQQTTTFTGHTGDVMS-LSLAPDTRLFVSGACDASAKLWDVREGMC 218
SS D C +WD +GQ T +S + +P+ + ++ D + KLWD +G C
Sbjct: 189 SSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKC 248
Query: 219 RQTFTGHESDINAICFFPN-----GNAFATGSDDATCRLFDLRADQ 259
+T+TGH+++ C F N G +GS+D +++L+ +
Sbjct: 249 LKTYTGHKNE--KYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKE 292
Score = 103 bits (258), Expect = 2e-22
Identities = 73/295 (24%), Positives = 132/295 (44%), Gaps = 9/295 (3%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
TL GH + ++ + + L S+S D + IW +Y I + A++
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIVTSSGDTTCAL 168
N + D I+++ + + + L GH+ Y+ CC F N IV+ S D + +
Sbjct: 100 NLLVSASDDKTLKIWDVSSG----KCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRI 155
Query: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES- 227
WD++TG+ T H+ V ++ D L VS + D ++WD G C +T ++
Sbjct: 156 WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP 215
Query: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSFSKSGRLLL 286
++ + F PNG + D T +L+D + L TY+ H N I + G+ ++
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 339
+G +D +W+ + L GH + V + T++ +A A D +K+W
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 80.1 bits (196), Expect = 3e-15
Identities = 42/163 (25%), Positives = 77/163 (47%), Gaps = 4/163 (2%)
Query: 179 TFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNG 238
T GHT V S+ +P+ S + D K+W +G +T +GH+ I+ + + +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 239 NAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
N + SDD T +++D+ + + L T H N + +F+ L+++G D + +W
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNY---VFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 298 DALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
D L H + VS + DG + + S+D +IW+
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD 199
Score = 60.5 bits (145), Expect = 2e-09
Identities = 44/170 (25%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHA-IPLRSSWVMTCAYAP 107
+TL H + A+H+ D L+VS+S DG IWD+ + + I + V ++P
Sbjct: 165 KTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSP 224
Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCC----RFLDDNQIVTSSGD 163
+G Y+ LDN +++ + + GH C IV+ S D
Sbjct: 225 NGKYILAATLDNTLKLWDYSKG----KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSED 280
Query: 164 TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC--DASAKLW 211
+W+++T + GHT V+S + P + S A D + KLW
Sbjct: 281 NLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 117 bits (294), Expect = 1e-26
Identities = 73/283 (25%), Positives = 134/283 (47%), Gaps = 21/283 (7%)
Query: 74 SQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA------------YAPSGNYVACGGLDNIC 121
S+D K + S + N+ +P ++ + C ++P+G ++A D +
Sbjct: 6 SRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLI 65
Query: 122 SIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQQTTTF 180
I+ + + + L GH +S + D+ ++V++S D T LWD+ +G+ T
Sbjct: 66 IIWGAY----DGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTL 121
Query: 181 TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA 240
GH+ V + P + L +SG+ D + K+W+V+ G C +T + H ++A+ F +G+
Sbjct: 122 KGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSL 181
Query: 241 FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
+GS D CR++D + Q L T D+ ++ V FS +G+ +L D +WD
Sbjct: 182 IVSGSYDGLCRIWDAASGQCLKTLVDDD-NPPVSFVKFSPNGKYILTATLDNTLKLWDYS 240
Query: 301 KADRAGVLAGHDNRVSCLGV---TDDGMAVATGSWDSFLKIWN 340
+ GH N C+ G + +GS D+ + IWN
Sbjct: 241 RGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 283
Score = 105 bits (263), Expect = 4e-23
Identities = 78/327 (23%), Positives = 148/327 (45%), Gaps = 10/327 (3%)
Query: 19 RDARKACADATLSQITNNIDPVGRI-QMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDG 77
+++R A A LS N V + TL GH + ++ + + L S+S D
Sbjct: 4 KESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADR 63
Query: 78 KLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSR 137
+IIW +Y + + + A++ + + D ++++++ + +
Sbjct: 64 LIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSG----KCLK 119
Query: 138 ELAGHTGYLSCCRF-LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDT 196
L GH+ Y+ CC F N I++ S D T +W+++TG+ T + H+ V ++
Sbjct: 120 TLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSG 179
Query: 197 RLFVSGACDASAKLWDVREGMCRQTFTGHES-DINAICFFPNGNAFATGSDDATCRLFDL 255
L VSG+ D ++WD G C +T ++ ++ + F PNG T + D T +L+D
Sbjct: 180 SLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDY 239
Query: 256 RADQELMTYS-HDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR 314
+ L TY+ H N I + G+ +++G +D +W+ + L GH +
Sbjct: 240 SRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV 299
Query: 315 V--SCLGVTDDGMAVATGSWDSFLKIW 339
V + T++ +A A D +K+W
Sbjct: 300 VISAACHPTENLIASAALENDKTIKLW 326
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 117 bits (293), Expect = 1e-26
Identities = 79/289 (27%), Positives = 132/289 (45%), Gaps = 18/289 (6%)
Query: 62 HWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG---------NYV 112
H+ +S++L +A G +W N +H + ++ V + P N
Sbjct: 238 HFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA 297
Query: 113 ACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALWDI 171
+C D +++L + E ++ GHT ++ + + + T+ D + LWD+
Sbjct: 298 SCAA-DGSVKLWSLDSDEPVA----DIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDL 352
Query: 172 ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINA 231
E ++ GH+ V ++ D L +G DA ++WD+R G C GH +I
Sbjct: 353 EAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYG 412
Query: 232 ICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLLLAGYD 290
I F PNG ATGS D TC+++DLR + + T +H N++ G+ G LL G
Sbjct: 413 INFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPI--HGNFLLTGAY 470
Query: 291 DFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
D +W LAGH+ +V L ++ DG +AT S+D K+W
Sbjct: 471 DNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 75.5 bits (184), Expect = 6e-14
Identities = 53/204 (25%), Positives = 88/204 (43%), Gaps = 11/204 (5%)
Query: 146 LSCCRFLDDNQIV-TSSGDTTCALWDIETGQQTTTFTGHTGDV--------MSLSLAPDT 196
+S C F +++++ T+ C LW + T GH +V ++SL P
Sbjct: 234 ISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKD 293
Query: 197 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLR 256
S A D S KLW + GH + + + P+G T D + RL+DL
Sbjct: 294 VNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLE 353
Query: 257 ADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVS 316
A +E++ ++ G+ ++F + G L G D VWD L GH +
Sbjct: 354 AQEEILHQEGHSM--GVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIY 411
Query: 317 CLGVTDDGMAVATGSWDSFLKIWN 340
+ + +G +ATGS D+ K+W+
Sbjct: 412 GINFSPNGYHIATGSGDNTCKVWD 435
Score = 74.3 bits (181), Expect = 1e-13
Identities = 53/205 (25%), Positives = 83/205 (40%), Gaps = 6/205 (2%)
Query: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
+ GH ++ + W R L + D +WD ++ S V A+ G+
Sbjct: 319 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 378
Query: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALW 169
GGLD +++L+T R L GH + F + I T SGD TC +W
Sbjct: 379 LAGTGGLDAFGRVWDLRTG----RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVW 434
Query: 170 DIETGQQTTTFTGHTGDVMSLSLAP-DTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
D+ + T H V + P ++GA D +AK+W +T GHE
Sbjct: 435 DLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK 494
Query: 229 INAICFFPNGNAFATGSDDATCRLF 253
+ + +G AT S D T +L+
Sbjct: 495 VMGLDISSDGQLIATCSYDRTFKLW 519
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 115 bits (288), Expect = 6e-26
Identities = 72/243 (29%), Positives = 115/243 (47%), Gaps = 7/243 (2%)
Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVT 159
V + A++P G + G D +Y +TR G ++ L GHTG + CRF D +
Sbjct: 24 VNSSAFSPDGQMLLTGSEDGC--VYGWETRSG--QLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 160 SSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMC 218
S+ D T LWD+ + GH V ++S +PD+R SG D LWDV+ G
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 219 RQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH-DNIICGITSVS 277
+ GH I + F P N ATGS D+T ++DLR +++ + I+ +
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLC 199
Query: 278 FSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLK 337
+S SG LL +G D ++W + L GH V + + D + +A+ + +K
Sbjct: 200 YSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVK 258
Query: 338 IWN 340
+W+
Sbjct: 259 VWD 261
Score = 107 bits (268), Expect = 1e-23
Identities = 64/212 (30%), Positives = 98/212 (46%), Gaps = 9/212 (4%)
Query: 133 VRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL-WDIETGQQTTTFTGHTGDVMSLS 191
VR + H G ++ F D Q++ + + C W+ +GQ GHTG V
Sbjct: 11 VRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCR 70
Query: 192 LAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251
+PD LF S +CD + +LWDV C + GH+ + + F P+ A+G D
Sbjct: 71 FSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVM 130
Query: 252 LFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRA---GV 307
L+D+++ Q L + H + I S FS + L G D ++WD A
Sbjct: 131 LWDVQSGQMLRLLVGHRD---SIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQA 187
Query: 308 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
L GH +SCL + G+ +A+GSWD + IW
Sbjct: 188 LEGHSANISCLCYSASGL-LASGSWDKTIHIW 218
Score = 89.4 bits (220), Expect = 4e-18
Identities = 65/285 (22%), Positives = 123/285 (43%), Gaps = 13/285 (4%)
Query: 54 HLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVA 113
H ++ + + D ++L++ S+DG + W++ + + + + V C ++P G+ A
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 114 CGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWDIE 172
D ++++ + R L GH + F D++ + S G D LWD++
Sbjct: 80 SASCDCTVRLWDV----ARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQ 135
Query: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR---EGMCRQTFTGHESDI 229
+GQ GH + S +P +G+ D++ +WD+R + Q GH ++I
Sbjct: 136 SGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANI 195
Query: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAG 288
+ +C+ +G A+GS D T ++ L+ + + S++FS L AG
Sbjct: 196 SCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLK--GHVTWVKSIAFSPDELWLASAG 252
Query: 289 YDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Y VWD L G + T DG + +G+ D
Sbjct: 253 YSRM-VKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAAD 296
Score = 87.8 bits (216), Expect = 1e-17
Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 1/203 (0%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
R L+GH + + + DSR L S D ++++WD + + + + + ++P+
Sbjct: 99 RVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPT 158
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL 168
N +A G D+ I++L+ V + L GH+ +SC + + + S D T +
Sbjct: 159 VNCLATGSWDSTVHIWDLRMVTPAVS-HQALEGHSANISCLCYSASGLLASGSWDKTIHI 217
Query: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
W T GH V S++ +PD S K+WD G C +T G
Sbjct: 218 WKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDV 277
Query: 229 INAICFFPNGNAFATGSDDATCR 251
+ F P+G +G+ D T R
Sbjct: 278 AHTCAFTPDGKILVSGAADQTRR 300
Score = 83.2 bits (204), Expect = 3e-16
Identities = 50/162 (30%), Positives = 77/162 (47%), Gaps = 4/162 (2%)
Query: 180 FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 239
F H G+V S + +PD ++ ++G+ D W+ R G GH + F P+G+
Sbjct: 17 FGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGH 76
Query: 240 AFATGSDDATCRLFDL-RADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
FA+ S D T RL+D+ RA + H + +VSFS R L +G D +WD
Sbjct: 77 LFASASCDCTVRLWDVARAKCLRVLKGHQR---SVETVSFSPDSRQLASGGWDKRVMLWD 133
Query: 299 ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
+L GH + + + +ATGSWDS + IW+
Sbjct: 134 VQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWD 175
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 114 bits (285), Expect = 1e-25
Identities = 70/242 (28%), Positives = 115/242 (47%), Gaps = 9/242 (3%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
+ L GH +Y + D L+S+S+DG + +W T + + V ++P
Sbjct: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCA 167
G Y GG D + ++ + + R AGH ++C RF + N + T S D T
Sbjct: 597 GYYFVSGGHDRVARLW----ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVR 652
Query: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
LWD+ G FTGH G + SL+ +P+ R +GA D LWD+ G+ GH
Sbjct: 653 LWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 712
Query: 228 DINAICFFPNGNAFATGSDDATCRLFD-LRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
+ ++ F +G A+GS D T RL+D ++A ++L T D+ ++ ++ + LL
Sbjct: 713 TVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLET---DDFTTATGHINLPENSQELL 769
Query: 287 AG 288
G
Sbjct: 770 LG 771
Score = 107 bits (266), Expect = 2e-23
Identities = 68/203 (33%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Query: 139 LAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
L GH+G + F D N +++SS D T LW ++T + GH V +P
Sbjct: 539 LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
Query: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
FVSG D A+LW + F GH +D+N F PN N ATGS D T RL+D+
Sbjct: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
Query: 258 DQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSC 317
+ ++ I S++FS +GR L G D +WD G L GH + V
Sbjct: 659 GNCVRIFTGHK--GPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCS 716
Query: 318 LGVTDDGMAVATGSWDSFLKIWN 340
L + DG +A+GS D+ +++W+
Sbjct: 717 LRFSRDGEILASGSMDNTVRLWD 739
Score = 100 bits (250), Expect = 1e-21
Identities = 71/250 (28%), Positives = 113/250 (45%), Gaps = 13/250 (5%)
Query: 57 KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116
K+ ++ +D L+ S D I D T +++ + S V +++P NY+
Sbjct: 503 KLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSS 562
Query: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWDIETGQ 175
D +++L+T V GH + +F S G D LW + Q
Sbjct: 563 EDGTVRLWSLQTFTCLVGYK----GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQ 618
Query: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFF 235
F GH DV P++ +G+ D + +LWDV G C + FTGH+ I+++ F
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678
Query: 236 PNGNAFATGSDDATCRLFDLRADQELMT---YSHDNIICGITSVSFSKSGRLLLAGYDDF 292
PNG ATG+ D L+D+ LM H + +C S+ FS+ G +L +G D
Sbjct: 679 PNGRFLATGATDGRVLLWDI--GHGLMVGELKGHTDTVC---SLRFSRDGEILASGSMDN 733
Query: 293 NCNVWDALKA 302
+WDA+KA
Sbjct: 734 TVRLWDAIKA 743
Score = 55.8 bits (133), Expect = 5e-08
Identities = 52/234 (22%), Positives = 90/234 (38%), Gaps = 25/234 (10%)
Query: 118 DNICSIYNLKTREGNVRVSRE----------LAGHTGYLSCCRFLDDNQIVTSS-GDTTC 166
D + I N+K VR+ + L + G L+ DD+ ++ D+T
Sbjct: 436 DKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQG-LTAVDVTDDSSLIAGGFADSTV 494
Query: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
+W + + + S+ A D L + D ++ D + + GH
Sbjct: 495 RVWSVTPKK-----------LRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHS 543
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
+ F P+ N + S+D T RL+ L+ L+ Y N + FS G +
Sbjct: 544 GPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY--PVWDTQFSPYGYYFV 601
Query: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
+G D +W + AGH V+C + VATGS D +++W+
Sbjct: 602 SGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD 655
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 111 bits (278), Expect = 8e-25
Identities = 89/339 (26%), Positives = 141/339 (41%), Gaps = 55/339 (16%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKV-HAIPLRSSWVMTCAYAP- 107
T +GH + ++ W D R L S ++G++++WD T +V + S W+ ++ P
Sbjct: 151 TCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPL 210
Query: 108 ----SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD 163
YVA D I++ T G R R L GHT ++C R+ D + ++S D
Sbjct: 211 HANPECRYVASSSKDGSVRIWD--TTAG--RCERILTGHTQSVTCLRWGGDGLLYSASQD 266
Query: 164 TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRL------------------------- 198
T +W G T GH V +++L+ D L
Sbjct: 267 RTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELK 326
Query: 199 -----------------FVSGACDASAKLWDVREGMCRQT-FTGHESDINAICFFPNGNA 240
VSG+ D + LW E T TGH++ IN + F P+
Sbjct: 327 ERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRI 386
Query: 241 FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
A+ S D + +L+D R + L + + + +++S RLL++G D VWD
Sbjct: 387 VASASFDKSIKLWDGRTGKYLASLRGH--VAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 444
Query: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
A L GH + V + + DG VA+G D L+IW
Sbjct: 445 AQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 90.1 bits (222), Expect = 3e-18
Identities = 66/254 (25%), Positives = 116/254 (45%), Gaps = 9/254 (3%)
Query: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
R R L GH + + WG D LL SASQD + +W ++ + WV T A
Sbjct: 237 RCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMAL 295
Query: 106 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT 165
+ + + G + + N + +G+++ +E A + R ++V+ S D T
Sbjct: 296 S-TDYALRTGAFEPAEASVNPQDLQGSLQELKERA--LSRYNLVRGQGPERLVSGSDDFT 352
Query: 166 CALWD-IETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG 224
LW E + T TGH + + +PD+R+ S + D S KLWD R G + G
Sbjct: 353 LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG 412
Query: 225 HESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGR 283
H + + I + + +GS D+T +++D++A + M H + + +V +S G+
Sbjct: 413 HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHAD---EVYAVDWSPDGQ 469
Query: 284 LLLAGYDDFNCNVW 297
+ +G D +W
Sbjct: 470 RVASGGKDKCLRIW 483
Score = 87.0 bits (214), Expect = 2e-17
Identities = 77/317 (24%), Positives = 137/317 (43%), Gaps = 35/317 (11%)
Query: 42 RIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVM 101
R R +L GH + ++ + + L S S D + WD T WV+
Sbjct: 101 RAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVL 160
Query: 102 TCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSC-----------CR 150
+ +++P G +A G + +++ T + +V R LAGH+ +++ CR
Sbjct: 161 SISWSPDGRKLASGCKNGQILLWDPSTGK---QVGRTLAGHSKWITGLSWEPLHANPECR 217
Query: 151 FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKL 210
+ + +SS D + +WD G+ TGHT V L D L+ S + D + K+
Sbjct: 218 Y-----VASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKV 271
Query: 211 WDVREGMCRQTFTGHESDINAICFFPNGNAFATGS---DDATCRLFDLRAD-QEL--MTY 264
W +G+ +T GH +N + A TG+ +A+ DL+ QEL
Sbjct: 272 WRAHDGVLCRTLQGHGHWVNTMA-LSTDYALRTGAFEPAEASVNPQDLQGSLQELKERAL 330
Query: 265 SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV-LAGHDNRVSCLGVTDD 323
S N++ G + L++G DDF +W + + + GH ++ + + D
Sbjct: 331 SRYNLVRG-------QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD 383
Query: 324 GMAVATGSWDSFLKIWN 340
VA+ S+D +K+W+
Sbjct: 384 SRIVASASFDKSIKLWD 400
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 106 bits (265), Expect = 3e-23
Identities = 67/213 (31%), Positives = 104/213 (48%), Gaps = 12/213 (5%)
Query: 129 REGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVM 188
R G ++ + L GH ++ C N+IV+ S D T +W TG+ T GHTG V
Sbjct: 248 RRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVW 307
Query: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDA 248
S + + + +SG+ D + K+W+ G C T GH S + C + +GS DA
Sbjct: 308 SSQMRDN--IIISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDA 363
Query: 249 TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV 307
T R++D+ Q L + H + + V + GR +++G DF VWD
Sbjct: 364 TLRVWDIETGQCLHVLMGH---VAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHT 418
Query: 308 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
L GH NRV L DG+ V +GS D+ +++W+
Sbjct: 419 LQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 449
Score = 102 bits (255), Expect = 4e-22
Identities = 75/261 (28%), Positives = 122/261 (46%), Gaps = 33/261 (12%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
TL GH + + MH + +VS S+D L +WD T +H + + V Y G
Sbjct: 338 TLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DG 393
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 169
V G D + +++ +T L GHT + +F D +V+ S DT+ +W
Sbjct: 394 RRVVSGAYDFMVKVWDPETET----CLHTLQGHTNRVYSLQF-DGIHVVSGSLDTSIRVW 448
Query: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG---HE 226
D+ETG T TGH + L + + VSG D++ K+WD++ G C QT G H+
Sbjct: 449 DVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQ 506
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQ---ELMTY--------------SHDNI 269
S + + F N N T SDD T +L+DL+ + L+T S+ +
Sbjct: 507 SAVTCLQF--NKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKL 564
Query: 270 ICGITSVSFSKSGRLLLAGYD 290
+C + S + ++ +LL+ +D
Sbjct: 565 VCAVGSRNGTEETKLLVLDFD 585
Score = 93.2 bits (230), Expect = 3e-19
Identities = 71/253 (28%), Positives = 119/253 (47%), Gaps = 20/253 (7%)
Query: 49 RTLRGHLAKIYAMHWGTDSR--LLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYA 106
RTL GH + W + R +++S S D L +W++ T +H + +S V C +
Sbjct: 297 RTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVR-CMHL 351
Query: 107 PSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTC 166
V+ G D +++++T + L GH + C ++ D ++V+ + D
Sbjct: 352 HEKRVVS-GSRDATLRVWDIETGQ----CLHVLMGHVAAVRCVQY-DGRRVVSGAYDFMV 405
Query: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
+WD ET T GHT V SL D VSG+ D S ++WDV G C T TGH+
Sbjct: 406 KVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQ 463
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN-IICGITSVSFSKSGRLL 285
S + + N +G+ D+T +++D++ Q L T N +T + F+K+ +
Sbjct: 464 SLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FV 519
Query: 286 LAGYDDFNCNVWD 298
+ DD +WD
Sbjct: 520 ITSSDDGTVKLWD 532
Score = 92.0 bits (227), Expect = 7e-19
Identities = 68/242 (28%), Positives = 115/242 (47%), Gaps = 18/242 (7%)
Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVT 159
V+TC GN + G DN +++ T + R L GHTG + + + DN I++
Sbjct: 265 VITCLQF-CGNRIVSGSDDNTLKVWSAVTG----KCLRTLVGHTGGVWSSQ-MRDNIIIS 318
Query: 160 SSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCR 219
S D T +W+ ETG+ T GHT V + L + VSG+ DA+ ++WD+ G C
Sbjct: 319 GSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCL 376
Query: 220 QTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSF 278
GH + + + + +G +G+ D +++D + L T H N + S
Sbjct: 377 HVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRV-----YSL 429
Query: 279 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
G +++G D + VWD + L GH + S + + D+ + +G+ DS +KI
Sbjct: 430 QFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKI 487
Query: 339 WN 340
W+
Sbjct: 488 WD 489
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 106 bits (265), Expect = 3e-23
Identities = 67/213 (31%), Positives = 104/213 (48%), Gaps = 12/213 (5%)
Query: 129 REGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVM 188
R G ++ + L GH ++ C N+IV+ S D T +W TG+ T GHTG V
Sbjct: 366 RRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVW 425
Query: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDA 248
S + + + +SG+ D + K+W+ G C T GH S + C + +GS DA
Sbjct: 426 SSQMRDN--IIISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDA 481
Query: 249 TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV 307
T R++D+ Q L + H + + V + GR +++G DF VWD
Sbjct: 482 TLRVWDIETGQCLHVLMGH---VAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHT 536
Query: 308 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
L GH NRV L DG+ V +GS D+ +++W+
Sbjct: 537 LQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 567
Score = 102 bits (255), Expect = 4e-22
Identities = 75/261 (28%), Positives = 122/261 (46%), Gaps = 33/261 (12%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
TL GH + + MH + +VS S+D L +WD T +H + + V Y G
Sbjct: 456 TLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DG 511
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 169
V G D + +++ +T L GHT + +F D +V+ S DT+ +W
Sbjct: 512 RRVVSGAYDFMVKVWDPETET----CLHTLQGHTNRVYSLQF-DGIHVVSGSLDTSIRVW 566
Query: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG---HE 226
D+ETG T TGH + L + + VSG D++ K+WD++ G C QT G H+
Sbjct: 567 DVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQ 624
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQ---ELMTY--------------SHDNI 269
S + + F N N T SDD T +L+DL+ + L+T S+ +
Sbjct: 625 SAVTCLQF--NKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKL 682
Query: 270 ICGITSVSFSKSGRLLLAGYD 290
+C + S + ++ +LL+ +D
Sbjct: 683 VCAVGSRNGTEETKLLVLDFD 703
Score = 93.2 bits (230), Expect = 3e-19
Identities = 71/253 (28%), Positives = 119/253 (47%), Gaps = 20/253 (7%)
Query: 49 RTLRGHLAKIYAMHWGTDSR--LLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYA 106
RTL GH + W + R +++S S D L +W++ T +H + +S V C +
Sbjct: 415 RTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVR-CMHL 469
Query: 107 PSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTC 166
V+ G D +++++T + L GH + C ++ D ++V+ + D
Sbjct: 470 HEKRVVS-GSRDATLRVWDIETGQ----CLHVLMGHVAAVRCVQY-DGRRVVSGAYDFMV 523
Query: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
+WD ET T GHT V SL D VSG+ D S ++WDV G C T TGH+
Sbjct: 524 KVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQ 581
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN-IICGITSVSFSKSGRLL 285
S + + N +G+ D+T +++D++ Q L T N +T + F+K+ +
Sbjct: 582 SLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FV 637
Query: 286 LAGYDDFNCNVWD 298
+ DD +WD
Sbjct: 638 ITSSDDGTVKLWD 650
Score = 92.0 bits (227), Expect = 7e-19
Identities = 68/242 (28%), Positives = 115/242 (47%), Gaps = 18/242 (7%)
Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVT 159
V+TC GN + G DN +++ T + R L GHTG + + + DN I++
Sbjct: 383 VITCLQF-CGNRIVSGSDDNTLKVWSAVTG----KCLRTLVGHTGGVWSSQ-MRDNIIIS 436
Query: 160 SSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCR 219
S D T +W+ ETG+ T GHT V + L + VSG+ DA+ ++WD+ G C
Sbjct: 437 GSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCL 494
Query: 220 QTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSF 278
GH + + + + +G +G+ D +++D + L T H N + S
Sbjct: 495 HVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRV-----YSL 547
Query: 279 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
G +++G D + VWD + L GH + S + + D+ + +G+ DS +KI
Sbjct: 548 QFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKI 605
Query: 339 WN 340
W+
Sbjct: 606 WD 607
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 106 bits (265), Expect = 3e-23
Identities = 67/213 (31%), Positives = 104/213 (48%), Gaps = 12/213 (5%)
Query: 129 REGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVM 188
R G ++ + L GH ++ C N+IV+ S D T +W TG+ T GHTG V
Sbjct: 286 RRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVW 345
Query: 189 SLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDA 248
S + + + +SG+ D + K+W+ G C T GH S + C + +GS DA
Sbjct: 346 SSQMRDN--IIISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDA 401
Query: 249 TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV 307
T R++D+ Q L + H + + V + GR +++G DF VWD
Sbjct: 402 TLRVWDIETGQCLHVLMGH---VAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHT 456
Query: 308 LAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
L GH NRV L DG+ V +GS D+ +++W+
Sbjct: 457 LQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 487
Score = 102 bits (255), Expect = 4e-22
Identities = 75/261 (28%), Positives = 122/261 (46%), Gaps = 33/261 (12%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
TL GH + + MH + +VS S+D L +WD T +H + + V Y G
Sbjct: 376 TLYGHTSTVRCMH--LHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DG 431
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 169
V G D + +++ +T L GHT + +F D +V+ S DT+ +W
Sbjct: 432 RRVVSGAYDFMVKVWDPETET----CLHTLQGHTNRVYSLQF-DGIHVVSGSLDTSIRVW 486
Query: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG---HE 226
D+ETG T TGH + L + + VSG D++ K+WD++ G C QT G H+
Sbjct: 487 DVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQ 544
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQ---ELMTY--------------SHDNI 269
S + + F N N T SDD T +L+DL+ + L+T S+ +
Sbjct: 545 SAVTCLQF--NKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKL 602
Query: 270 ICGITSVSFSKSGRLLLAGYD 290
+C + S + ++ +LL+ +D
Sbjct: 603 VCAVGSRNGTEETKLLVLDFD 623
Score = 93.2 bits (230), Expect = 3e-19
Identities = 71/253 (28%), Positives = 119/253 (47%), Gaps = 20/253 (7%)
Query: 49 RTLRGHLAKIYAMHWGTDSR--LLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYA 106
RTL GH + W + R +++S S D L +W++ T +H + +S V C +
Sbjct: 335 RTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVR-CMHL 389
Query: 107 PSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTC 166
V+ G D +++++T + L GH + C ++ D ++V+ + D
Sbjct: 390 HEKRVVS-GSRDATLRVWDIETGQ----CLHVLMGHVAAVRCVQY-DGRRVVSGAYDFMV 443
Query: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
+WD ET T GHT V SL D VSG+ D S ++WDV G C T TGH+
Sbjct: 444 KVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQ 501
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN-IICGITSVSFSKSGRLL 285
S + + N +G+ D+T +++D++ Q L T N +T + F+K+ +
Sbjct: 502 SLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FV 557
Query: 286 LAGYDDFNCNVWD 298
+ DD +WD
Sbjct: 558 ITSSDDGTVKLWD 570
Score = 92.0 bits (227), Expect = 7e-19
Identities = 68/242 (28%), Positives = 115/242 (47%), Gaps = 18/242 (7%)
Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVT 159
V+TC GN + G DN +++ T + R L GHTG + + + DN I++
Sbjct: 303 VITCLQF-CGNRIVSGSDDNTLKVWSAVTG----KCLRTLVGHTGGVWSSQ-MRDNIIIS 356
Query: 160 SSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCR 219
S D T +W+ ETG+ T GHT V + L + VSG+ DA+ ++WD+ G C
Sbjct: 357 GSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLRVWDIETGQCL 414
Query: 220 QTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSF 278
GH + + + + +G +G+ D +++D + L T H N + S
Sbjct: 415 HVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRV-----YSL 467
Query: 279 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338
G +++G D + VWD + L GH + S + + D+ + +G+ DS +KI
Sbjct: 468 QFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKI 525
Query: 339 WN 340
W+
Sbjct: 526 WD 527
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 105 bits (263), Expect = 4e-23
Identities = 71/292 (24%), Positives = 122/292 (41%), Gaps = 7/292 (2%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
R +GH + + + +++ L S S D L++W ++ + V ++PS
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCA 167
G+ +A G D I+ + +G V R HT + F D Q VT+S D T
Sbjct: 73 GHLLASGSRDKTVRIW-VPNVKGESTVFR---AHTATVRSVHFCSDGQSFVTASDDKTVK 128
Query: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
+W + + + H V +PD RL VS + D + KLWD C ++ H
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGG 188
Query: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287
+ + F P+G A D T +++D+R + L Y + + +SF SG L+
Sbjct: 189 FVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS--AAVNGLSFHPSGNYLIT 246
Query: 288 GYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
D + D ++ L GH + + + G A+G D + +W
Sbjct: 247 ASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 87.4 bits (215), Expect = 2e-17
Identities = 49/207 (23%), Positives = 92/207 (44%), Gaps = 3/207 (1%)
Query: 135 VSRELAGHTGYLSCCRF-LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLA 193
+ R GH ++C F ++ Q+ + S D+ +W ++ + FTGH V ++ +
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFS 70
Query: 194 PDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253
P L SG+ D + ++W F H + + ++ F +G +F T SDD T +++
Sbjct: 71 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Query: 254 DLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDN 313
+ L + S I + FS GRL+++ DD +WD + H
Sbjct: 131 ATHRQKFLFSLSQH--INWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGG 188
Query: 314 RVSCLGVTDDGMAVATGSWDSFLKIWN 340
V+ + G +A D+ +K+W+
Sbjct: 189 FVTYVDFHPSGTCIAAAGMDNTVKVWD 215
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 105 bits (263), Expect = 4e-23
Identities = 71/292 (24%), Positives = 122/292 (41%), Gaps = 7/292 (2%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
R +GH + + + +++ L S S D L++W ++ + V ++PS
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCA 167
G+ +A G D I+ + +G V R HT + F D Q VT+S D T
Sbjct: 73 GHLLASGSRDKTVRIW-VPNVKGESTVFR---AHTATVRSVHFCSDGQSFVTASDDKTVK 128
Query: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
+W + + + H V +PD RL VS + D + KLWD C ++ H
Sbjct: 129 VWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGG 188
Query: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287
+ + F P+G A D T +++D+R + L Y + + +SF SG L+
Sbjct: 189 FVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS--AAVNGLSFHPSGNYLIT 246
Query: 288 GYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
D + D ++ L GH + + + G A+G D + +W
Sbjct: 247 ASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 87.4 bits (215), Expect = 2e-17
Identities = 49/207 (23%), Positives = 92/207 (44%), Gaps = 3/207 (1%)
Query: 135 VSRELAGHTGYLSCCRF-LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLA 193
+ R GH ++C F ++ Q+ + S D+ +W ++ + FTGH V ++ +
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFS 70
Query: 194 PDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 253
P L SG+ D + ++W F H + + ++ F +G +F T SDD T +++
Sbjct: 71 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
Query: 254 DLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDN 313
+ L + S I + FS GRL+++ DD +WD + H
Sbjct: 131 ATHRQKFLFSLSQH--INWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGG 188
Query: 314 RVSCLGVTDDGMAVATGSWDSFLKIWN 340
V+ + G +A D+ +K+W+
Sbjct: 189 FVTYVDFHPSGTCIAAAGMDNTVKVWD 215
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 105 bits (262), Expect = 6e-23
Identities = 57/203 (28%), Positives = 102/203 (50%), Gaps = 3/203 (1%)
Query: 139 LAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
L GH G + RFL D+ +++ S D + WD+ + T + GH V L ++P +
Sbjct: 338 LRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 397
Query: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
F SG+ D +A+LW + + GH +D++ + F PN N ATGS D T RL+ +
Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 457
Query: 258 DQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSC 317
+ ++ + S++FS +G+ L + +D +WD L GH + ++
Sbjct: 458 GNSVRLFTGHR--GPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITS 515
Query: 318 LGVTDDGMAVATGSWDSFLKIWN 340
L + D +A+ S D+ +++W+
Sbjct: 516 LTFSPDSGLIASASMDNSVRVWD 538
Score = 103 bits (256), Expect = 3e-22
Identities = 66/214 (30%), Positives = 104/214 (48%), Gaps = 15/214 (7%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD--SYTTNKV---HAIPLRSSWVMTC 103
+ LRGH +Y+ + DS L+S S+D + WD S+T + HA P+ W +
Sbjct: 336 KILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPV---WDLDI 392
Query: 104 AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSG 162
+ P Y A G D +++ R +R+ AGH + C +F + N + T S
Sbjct: 393 S--PYSLYFASGSHDRTARLWSFD-RTYPLRI---YAGHLADVDCVKFHPNSNYLATGST 446
Query: 163 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
D T LW + G FTGH G V+SL+ +P+ + S D KLWD+ G +
Sbjct: 447 DKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKEL 506
Query: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFDLR 256
GH +I ++ F P+ A+ S D + R++D+R
Sbjct: 507 RGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR 540
Score = 64.3 bits (155), Expect = 1e-10
Identities = 43/171 (25%), Positives = 68/171 (39%), Gaps = 2/171 (1%)
Query: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDI 229
D G + GH G V S D+ +S + D S + WD+ + GH +
Sbjct: 328 DDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPV 387
Query: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGY 289
+ P FA+GS D T RL+ L Y+ + + V F + L G
Sbjct: 388 WDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYA--GHLADVDCVKFHPNSNYLATGS 445
Query: 290 DDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
D +W A + + + GH V L + +G +A+ D LK+W+
Sbjct: 446 TDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWD 496
Score = 37.7 bits (86), Expect = 0.015
Identities = 33/181 (18%), Positives = 65/181 (35%), Gaps = 34/181 (18%)
Query: 192 LAPDTRLFVSGACDASAKLWDVRE--------------------------------GMCR 219
++PD++L +G ++ KLW +R G
Sbjct: 276 ISPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDILEEEDDEDDNAGTEM 335
Query: 220 QTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFS 279
+ GH + + F + + + S+D + R +DL + + Y + + S
Sbjct: 336 KILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLY--QGHAYPVWDLDIS 393
Query: 280 KSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
+G D +W + + AGH V C+ + +ATGS D +++W
Sbjct: 394 PYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLW 453
Query: 340 N 340
+
Sbjct: 454 S 454
Score = 33.5 bits (75), Expect = 0.28
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTT 87
+ LRGH I ++ + DS L+ SAS D + +WD T
Sbjct: 504 KELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNT 542
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 102 bits (255), Expect = 4e-22
Identities = 54/197 (27%), Positives = 102/197 (51%), Gaps = 5/197 (2%)
Query: 59 YAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLD 118
+ + + DS+ L + + GK+ I+ + K +++ R ++++ AY+P G Y+A G +D
Sbjct: 110 WTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAID 169
Query: 119 NICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQI-VTSSGDTTCALWDIETGQQT 177
I +I+++ T ++ L GH + F D+Q+ VT+S D ++D++
Sbjct: 170 GIINIFDIATG----KLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLA 225
Query: 178 TTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPN 237
T +GH V++++ PD FVS + D S K+WDV C TF H+ + + + N
Sbjct: 226 GTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGN 285
Query: 238 GNAFATGSDDATCRLFD 254
G+ + DD ++D
Sbjct: 286 GSKIVSVGDDQEIHIYD 302
Score = 82.4 bits (202), Expect = 5e-16
Identities = 58/250 (23%), Positives = 117/250 (46%), Gaps = 7/250 (2%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
+L GH + ++ + S+S D + +WD ++ +I T A++P
Sbjct: 59 SLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDS 118
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 169
Y+A G +I+ +++ G S + G LS D + + + D ++
Sbjct: 119 QYLATGTHVGKVNIFGVES--GKKEYSLDTRGKF-ILSIAYSPDGKYLASGAIDGIINIF 175
Query: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDI 229
DI TG+ T GH + SL+ +PD++L V+ + D K++DV+ T +GH S +
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 230 NAICFFPNGNAFATGSDDATCRLFDLRADQELMT-YSHDNIICGITSVSFSKSGRLLLAG 288
+ F P+ F + S D + +++D+ + T + H + + G V ++ +G +++
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWG---VKYNGNGSKIVSV 292
Query: 289 YDDFNCNVWD 298
DD +++D
Sbjct: 293 GDDQEIHIYD 302
Score = 81.6 bits (200), Expect = 9e-16
Identities = 58/230 (25%), Positives = 101/230 (43%), Gaps = 5/230 (2%)
Query: 112 VACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWD 170
V G LD++ ++ K R+ + + L GH + I SS D LWD
Sbjct: 35 VVTGSLDDLVKVW--KWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWD 92
Query: 171 IETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN 230
+E G+Q + D +L+ +PD++ +G ++ V G + I
Sbjct: 93 LENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFIL 152
Query: 231 AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYD 290
+I + P+G A+G+ D +FD+ + L T + I S++FS +LL+ D
Sbjct: 153 SIAYSPDGKYLASGAIDGIINIFDIATGKLLHTL--EGHAMPIRSLTFSPDSQLLVTASD 210
Query: 291 DFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
D ++D A+ AG L+GH + V + D + S D +K+W+
Sbjct: 211 DGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWD 260
>gi|5174447 guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 [Homo sapiens]
Length = 317
Score = 102 bits (254), Expect = 5e-22
Identities = 73/260 (28%), Positives = 121/260 (46%), Gaps = 15/260 (5%)
Query: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
+R LRGH + + +D + +S S DG L +WD T + V++ A++
Sbjct: 56 QRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS 115
Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL--DDNQIVTSSG-DT 164
+ G D ++N G + + + H+ ++SC RF N I+ S G D
Sbjct: 116 DNRQIVSGSRDKTIKLWNTL---GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDK 172
Query: 165 TCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG 224
+W++ + T GHTG + +++++PD L SG D A LWD+ EG T G
Sbjct: 173 LVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232
Query: 225 HESDINAICFFPNGNAFATGSDDATCRLFDLRA-------DQELMTYSHDNIICGITSVS 277
+ INA+CF PN + + + +++DL QE+++ S TS++
Sbjct: 233 GDI-INALCFSPN-RYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLA 290
Query: 278 FSKSGRLLLAGYDDFNCNVW 297
+S G+ L AGY D VW
Sbjct: 291 WSADGQTLFAGYTDNLVRVW 310
Score = 83.2 bits (204), Expect = 3e-16
Identities = 72/252 (28%), Positives = 112/252 (44%), Gaps = 14/252 (5%)
Query: 97 SSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTREGNVRV-SRELAGHTGYLSCCRFLDD 154
+ WV A P + + D ++ L E N + R L GH+ ++S D
Sbjct: 15 NGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD 74
Query: 155 NQIVTS-SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDV 213
Q S S D T LWD+ TG T F GHT DV+S++ + D R VSG+ D + KLW+
Sbjct: 75 GQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT 134
Query: 214 REGMCRQTF--TGHESDINAICFFPNGN--AFATGSDDATCRLFDLRADQELMTYSHDNI 269
G+C+ T H ++ + F PN + + D ++++L A+ +L T +H
Sbjct: 135 L-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKT-NHIGH 191
Query: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHD-NRVSCLGVTDDGMAVA 328
+ +V+ S G L +G D +WD + L G D C + A
Sbjct: 192 TGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAA 251
Query: 329 TGSWDSFLKIWN 340
TG +KIW+
Sbjct: 252 TG---PSIKIWD 260
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 102 bits (254), Expect = 5e-22
Identities = 73/293 (24%), Positives = 125/293 (42%), Gaps = 9/293 (3%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
R +GH A I ++ + + L +AS D L++W+ + + V + ++P
Sbjct: 12 RYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPH 71
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCA 167
GN +A D ++ + + G E HT + F D Q + T+S D +
Sbjct: 72 GNLLASASRDRTVRLW-IPDKRGKFS---EFKAHTAPVRSVDFSADGQFLATASEDKSIK 127
Query: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227
+W + + + HT V +PD RL VS + D + K+WD C F+
Sbjct: 128 VWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVG 187
Query: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-HDNIICGITSVSFSKSGRLLL 286
N + F P+G A+ D T +++D+R ++ L Y H G+ +SF SG L+
Sbjct: 188 FANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSG---GVNCISFHPSGNYLI 244
Query: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
D + D L+ L GH V + + G A+G D+ + +W
Sbjct: 245 TASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
Score = 82.8 bits (203), Expect = 4e-16
Identities = 45/209 (21%), Positives = 88/209 (42%), Gaps = 5/209 (2%)
Query: 52 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 111
+ H A + ++ + D + L +AS+D + +W Y ++++ + WV ++P G
Sbjct: 99 KAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRL 158
Query: 112 VACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWD 170
+ D I++ N + + G+ + F + S+G D T +WD
Sbjct: 159 IVSCSEDKTIKIWDTT----NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWD 214
Query: 171 IETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN 230
+ + + H+G V +S P ++ + D + K+ D+ EG T GH +
Sbjct: 215 VRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVF 274
Query: 231 AICFFPNGNAFATGSDDATCRLFDLRADQ 259
+ F G FA+G D L+ D+
Sbjct: 275 TVSFSKGGELFASGGADTQVLLWRTNFDE 303
Score = 71.2 bits (173), Expect = 1e-12
Identities = 45/164 (27%), Positives = 74/164 (45%), Gaps = 8/164 (4%)
Query: 180 FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 239
F GH + SL L+P+ + + + D LW+ + + GH+ + ++ F P+GN
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 240 AFATGSDDATCRLF--DLRAD-QELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNV 296
A+ S D T RL+ D R E ++ + SV FS G+ L +D + V
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHT-----APVRSVDFSADGQFLATASEDKSIKV 128
Query: 297 WDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
W + L H + V C + DG + + S D +KIW+
Sbjct: 129 WSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWD 172
Score = 69.7 bits (169), Expect = 4e-12
Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 4/186 (2%)
Query: 156 QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVRE 215
Q+ T+S DT LW+ + + + GH V S+ +P L S + D + +LW +
Sbjct: 32 QLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDK 91
Query: 216 GMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMT-YSHDNIICGIT 274
F H + + ++ F +G AT S+D + +++ + + L + Y H + +
Sbjct: 92 RGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTH---WVR 148
Query: 275 SVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDS 334
FS GRL+++ +D +WD + + + G +A+ D
Sbjct: 149 CAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQ 208
Query: 335 FLKIWN 340
+K+W+
Sbjct: 209 TVKVWD 214
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 102 bits (253), Expect = 6e-22
Identities = 73/241 (30%), Positives = 105/241 (43%), Gaps = 42/241 (17%)
Query: 141 GHTGYLS-CCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 199
GHT +LS CC +++ TSSGDTT LWD+ G TF GH+ V S +
Sbjct: 392 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFV 451
Query: 200 VSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLR--- 256
S + D ++K+WDV CR T GH +N+I FFP N T S D T ++D R
Sbjct: 452 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGI 511
Query: 257 ADQELMTYSH---DNII------------CGIT----------------------SVSFS 279
+Q L + H D I CG+T V+F
Sbjct: 512 CEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFD 571
Query: 280 KSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
SGR+L + ++ D LK+ L GH+N + + DG + +G D ++ W
Sbjct: 572 SSGRVLAQASGNGVIHLLD-LKSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTW 630
Query: 340 N 340
+
Sbjct: 631 S 631
Score = 80.9 bits (198), Expect = 2e-15
Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 12/231 (5%)
Query: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
L ++S D + +WD + + S V +C + GN+VA LD I+++ +
Sbjct: 409 LATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSE 468
Query: 130 EGNVRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVM 188
R L GHT ++ F N ++TSS D T ++WD TG + GH +
Sbjct: 469 ----RCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSIN 524
Query: 189 SLSLAPDTRLFVSGACDAS--AKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSD 246
P + S CDA KLWD R+ + + S N + F +G A S
Sbjct: 525 DAIFDPRGHMIAS--CDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASG 582
Query: 247 DATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
+ L DL++ + H+N +V FS G +L +G D W
Sbjct: 583 NGVIHLLDLKSGEIHKLMGHEN---EAHTVVFSHDGEILFSGGSDGTVRTW 630
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 180 FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 239
F H V +S+ P + VS D K+ + + T GH ++ CF P+G+
Sbjct: 348 FRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGD 407
Query: 240 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDA 299
AT S D T +L+DL ++T+ + + S ++ G + + D +WD
Sbjct: 408 KLATSSGDTTVKLWDLCKGDCILTFEGHS--RAVWSCTWHSCGNFVASSSLDKTSKIWDV 465
Query: 300 LKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
L GH + V+ + + T S D L IW+
Sbjct: 466 NSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWD 506
Score = 38.5 bits (88), Expect = 0.009
Identities = 33/168 (19%), Positives = 69/168 (41%), Gaps = 8/168 (4%)
Query: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
R R TL GH + ++ + S L+++S D L IWD+ T ++ + +
Sbjct: 469 RCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIF 528
Query: 106 APSGNYVACGGLDNICSIYNLKTREG--NVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD 163
P G+ +A + +++ + ++ + + S R L +SG+
Sbjct: 529 DPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVL-----AQASGN 583
Query: 164 TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 211
L D+++G + GH + ++ + D + SG D + + W
Sbjct: 584 GVIHLLDLKSG-EIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTW 630
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 99.4 bits (246), Expect = 4e-21
Identities = 84/357 (23%), Positives = 151/357 (42%), Gaps = 32/357 (8%)
Query: 6 QLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRR-TLRGHLAKIYAMHWG 64
+L+++ +L++++ +A++ + DP I + L GH + + + +
Sbjct: 60 RLQKKVMELESKLNEAKEEFTSG--GPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFH 117
Query: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
++VSAS+D + +WD T + + + V ++ SG +A D ++
Sbjct: 118 PVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLW 177
Query: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTCALWDIETGQQTTTFTGH 183
+ + E R + GH +S + + + IV++S D T +W+++TG TFTGH
Sbjct: 178 DFQGFE----CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGH 233
Query: 184 TGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPN------ 237
V + D L S + D + ++W V C+ HE + I + P
Sbjct: 234 REWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSI 293
Query: 238 --------------GNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSG 282
G +GS D T +++D+ LMT HDN + G+ F G
Sbjct: 294 SEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL---FHSGG 350
Query: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
+ +L+ DD VWD L H++ V+ L V TGS D +K+W
Sbjct: 351 KFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 90.9 bits (224), Expect = 1e-18
Identities = 63/272 (23%), Positives = 116/272 (42%), Gaps = 29/272 (10%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
RTL+GH + + + +LL S S D + +WD + + V + A P+
Sbjct: 144 RTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPN 203
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
G+++ D ++ ++T + GH ++ R D ++ S S D T
Sbjct: 204 GDHIVSASRDKTIKMWEVQTGY----CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259
Query: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTR--------------------LFVSGACDAS 207
+W + T + H V +S AP++ +SG+ D +
Sbjct: 260 VWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKT 319
Query: 208 AKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYS-H 266
K+WDV GMC T GH++ + + F G + +DD T R++D + + + T + H
Sbjct: 320 IKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAH 379
Query: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
++ + TS+ F K+ ++ G D VW+
Sbjct: 380 EHFV---TSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 86.7 bits (213), Expect = 3e-17
Identities = 61/223 (27%), Positives = 101/223 (45%), Gaps = 19/223 (8%)
Query: 137 RELAGHTGYLSCCRFLDDNQIVTS-SGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPD 195
R L GHT + F +++ S S D T LWD + + T GH +V S+++ P+
Sbjct: 144 RTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPN 203
Query: 196 TRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF-- 253
VS + D + K+W+V+ G C +TFTGH + + +G A+ S+D T R++
Sbjct: 204 GDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVV 263
Query: 254 -------DLRADQELM---------TYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
+LR + ++ +YS + G + K G LL+G D +W
Sbjct: 264 ATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 323
Query: 298 DALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
D L GHDN V + G + + + D L++W+
Sbjct: 324 DVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWD 366
Score = 70.5 bits (171), Expect = 2e-12
Identities = 50/229 (21%), Positives = 89/229 (38%), Gaps = 25/229 (10%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
RT+ GH + ++ + +VSAS+D + +W+ T V WV
Sbjct: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ------------ 156
G +A D ++ + T+E EL H + C + ++
Sbjct: 246 GTLIASCSNDQTVRVWVVATKE----CKAELREHEHVVECISWAPESSYSSISEATGSET 301
Query: 157 ---------IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDAS 207
+++ S D T +WD+ TG T GH V + + +S A D +
Sbjct: 302 KKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKT 361
Query: 208 AKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLR 256
++WD + C +T HE + ++ F TGS D T ++++ R
Sbjct: 362 LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 34.7 bits (78), Expect = 0.13
Identities = 18/68 (26%), Positives = 31/68 (45%)
Query: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
+T V F ++++ +D VWD D L GH + V + G +A+ S
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
Query: 333 DSFLKIWN 340
D +K+W+
Sbjct: 171 DMTIKLWD 178
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 97.8 bits (242), Expect = 1e-20
Identities = 72/252 (28%), Positives = 118/252 (46%), Gaps = 18/252 (7%)
Query: 100 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIV 158
V C + P+G+ +A G D + ++N+ G+ L GH+G + + D + +
Sbjct: 69 VYCCKFHPNGSTLASAGFDRLILLWNVY---GDCDNYATLKGHSGAVMELHYNTDGSMLF 125
Query: 159 TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP-DTRLFVSGACDASAKLWDVREGM 217
++S D T A+WD ETG++ GHT V S A +L +G+ D + KLWD+R+
Sbjct: 126 SASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKA 185
Query: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
QTF + + A+ F + +G D +++DLR Q +TY+ +T +S
Sbjct: 186 AIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR--QNKLTYTMRGHADSVTGLS 242
Query: 278 FSKSGRLLLAGYDDFNCNVWDA---------LKADRAGVLAGHDNRVSCLGVTDDGMAVA 328
S G LL+ D VWD +K + V N + C + DG +A
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC-SWSPDGSKIA 301
Query: 329 TGSWDSFLKIWN 340
GS D F+ +W+
Sbjct: 302 AGSADRFVYVWD 313
Score = 92.4 bits (228), Expect = 5e-19
Identities = 66/251 (26%), Positives = 116/251 (46%), Gaps = 15/251 (5%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
TL+GH + +H+ TD +L SAS D + +WDS T +V + +S+V +C A G
Sbjct: 104 TLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRG 163
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCAL 168
+ C G D+ +K + + + + +T + F D +QI++ D +
Sbjct: 164 PQLVCTGSDD----GTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKV 219
Query: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR----EGMCRQTFTG 224
WD+ + T T GH V LSL+ + +S A D + ++WDVR + C + F G
Sbjct: 220 WDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQG 279
Query: 225 H----ESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSK 280
+ E ++ + P+G+ A GS D ++D + + L Y I V+F
Sbjct: 280 NVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRIL--YKLPGHAGSINEVAFHP 337
Query: 281 SGRLLLAGYDD 291
++++ D
Sbjct: 338 DEPIIISASSD 348
Score = 91.7 bits (226), Expect = 9e-19
Identities = 54/205 (26%), Positives = 99/205 (48%), Gaps = 6/205 (2%)
Query: 139 LAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWDIETG-QQTTTFTGHTGDVMSLSLAPDT 196
L+GH G + CC+F + + S+G D LW++ T GH+G VM L D
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 197 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNG-NAFATGSDDATCRLFDL 255
+ S + D + +WD G + GH S +N+ G TGSDD T +L+D+
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 256 RADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRV 315
R + T+ + + +T F+ + +++G D + VWD + + GH + V
Sbjct: 182 RKKAAIQTFQNTYQVLAVT---FNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSV 238
Query: 316 SCLGVTDDGMAVATGSWDSFLKIWN 340
+ L ++ +G + + + D+ +++W+
Sbjct: 239 TGLSLSSEGSYLLSNAMDNTVRVWD 263
Score = 89.7 bits (221), Expect = 3e-18
Identities = 77/300 (25%), Positives = 125/300 (41%), Gaps = 24/300 (8%)
Query: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIW------DSYTTNKVHAIPLRSSWVMTCA 104
L GH ++Y + + L SA D +++W D+Y T K H S VM
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGH-----SGAVMELH 116
Query: 105 YAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCC--RFLDDNQIVTSSG 162
Y G+ + D ++++ +T E RV R L GHT +++ C + T S
Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGE---RVKR-LKGHTSFVNSCYPARRGPQLVCTGSD 172
Query: 163 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
D T LWDI TF +T V++++ + +SG D K+WD+R+ T
Sbjct: 173 DGTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTM 231
Query: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFDLR--ADQE----LMTYSHDNIICGITSV 276
GH + + G+ + + D T R++D+R A +E + + N +
Sbjct: 232 RGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRC 291
Query: 277 SFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFL 336
S+S G + AG D VWD L GH ++ + D + + S D L
Sbjct: 292 SWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRL 351
Score = 47.0 bits (110), Expect = 2e-05
Identities = 28/163 (17%), Positives = 66/163 (40%), Gaps = 5/163 (3%)
Query: 57 KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116
++ A+ + S ++S D + +WD + + + V + + G+Y+
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNA 254
Query: 117 LDNICSIYNLKTREGNVRVSRELAGHT-----GYLSCCRFLDDNQIVTSSGDTTCALWDI 171
+DN +++++ R + G+ L C D ++I S D +WD
Sbjct: 255 MDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDT 314
Query: 172 ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVR 214
+ + GH G + ++ PD + +S + D + +++
Sbjct: 315 TSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/140 (22%), Positives = 59/140 (42%), Gaps = 18/140 (12%)
Query: 33 ITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD--------- 83
I N+I Q + T+RGH + + ++ L+S + D + +WD
Sbjct: 213 IDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKER 272
Query: 84 --SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAG 141
VH ++ C+++P G+ +A G D +++ +R R+ +L G
Sbjct: 273 CVKIFQGNVHNFEKN---LLRCSWSPDGSKIAAGSADRFVYVWDTTSR----RILYKLPG 325
Query: 142 HTGYLSCCRFLDDNQIVTSS 161
H G ++ F D I+ S+
Sbjct: 326 HAGSINEVAFHPDEPIIISA 345
Score = 28.9 bits (63), Expect = 6.9
Identities = 10/34 (29%), Positives = 19/34 (55%)
Query: 307 VLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
+L+GH+ V C +G +A+ +D + +WN
Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWN 94
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 95.1 bits (235), Expect = 8e-20
Identities = 53/200 (26%), Positives = 96/200 (48%), Gaps = 5/200 (2%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
+L GH + + ++ T L+V+ SQ G + +WD + + + + + + P G
Sbjct: 58 SLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYG 117
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT-TCAL 168
+VA G D +++++ R+G V R GH+ + C RF D + + S+ D T L
Sbjct: 118 EFVASGSQDTNIKLWDIR-RKGCVFRYR---GHSQAVRCLRFSPDGKWLASAADDHTVKL 173
Query: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESD 228
WD+ G+ + F GHTG V + P+ L SG+ D + + WD+ + G
Sbjct: 174 WDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGP 233
Query: 229 INAICFFPNGNAFATGSDDA 248
+ ++ F P+G +G D+
Sbjct: 234 VRSVLFNPDGCCLYSGCQDS 253
Score = 92.0 bits (227), Expect = 7e-19
Identities = 65/229 (28%), Positives = 98/229 (42%), Gaps = 9/229 (3%)
Query: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIVTSSGDTTC 166
SG +A GG D C + + N +S L GHT + R + IV S +
Sbjct: 32 SGRLLATGGDD--CRVNLWSINKPNCIMS--LTGHTSPVESVRLNTPEELIVAGSQSGSI 87
Query: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
+WD+E + T GH ++ SL P SG+ D + KLWD+R C + GH
Sbjct: 88 RVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHS 147
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLL 285
+ + F P+G A+ +DD T +L+DL A + + + H + V F + LL
Sbjct: 148 QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG---PVNVVEFHPNEYLL 204
Query: 286 LAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDS 334
+G D WD K + G V + DG + +G DS
Sbjct: 205 ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
Score = 86.7 bits (213), Expect = 3e-17
Identities = 64/240 (26%), Positives = 101/240 (42%), Gaps = 8/240 (3%)
Query: 54 HLAKIYAMHWGTDS-RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYV 112
H + + ++ G S RLL + D ++ +W N + ++ +S V + +
Sbjct: 19 HASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELI 78
Query: 113 ACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCALWDI 171
G +++L+ ++ R L GH + F + V S S DT LWDI
Sbjct: 79 VAGSQSGSIRVWDLEA----AKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDI 134
Query: 172 ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINA 231
+ GH+ V L +PD + S A D + KLWD+ G F GH +N
Sbjct: 135 RRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNV 194
Query: 232 ICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 291
+ F PN A+GS D T R +DL Q + + + SV F+ G L +G D
Sbjct: 195 VEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEP--GPVRSVLFNPDGCCLYSGCQD 252
Score = 86.3 bits (212), Expect = 4e-17
Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 4/185 (2%)
Query: 157 IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
+ T D LW I + TGHT V S+ L L V+G+ S ++WD+
Sbjct: 36 LATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA 95
Query: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITS 275
+T GH+++I ++ F P G A+GS D +L+D+R + Y H +
Sbjct: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQ---AVRC 152
Query: 276 VSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 335
+ FS G+ L + DD +WD GH V+ + + +A+GS D
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRT 212
Query: 336 LKIWN 340
++ W+
Sbjct: 213 IRFWD 217
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 5/171 (2%)
Query: 172 ETGQQTTTFTGHTGDVMSLSLAPDT-RLFVSGACDASAKLWDVREGMCRQTFTGHESDIN 230
+T + H +V SL L + RL +G D LW + + C + TGH S +
Sbjct: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVE 67
Query: 231 AICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLLLAGY 289
++ GS + R++DL A + L T H IC S+ F G + +G
Sbjct: 68 SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANIC---SLDFHPYGEFVASGS 124
Query: 290 DDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
D N +WD + GH V CL + DG +A+ + D +K+W+
Sbjct: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175
Score = 65.5 bits (158), Expect = 7e-11
Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 5/159 (3%)
Query: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
RTL GH A I ++ + + S SQD + +WD V S V ++P
Sbjct: 99 RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
Query: 109 GNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTCA 167
G ++A D+ +++L ++ E GHTG ++ F + ++ S S D T
Sbjct: 159 GKWLASAADDHTVKLWDLTAG----KMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
Query: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDA 206
WD+E Q + G G V S+ PD SG D+
Sbjct: 215 FWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDS 253
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 94.7 bits (234), Expect = 1e-19
Identities = 65/265 (24%), Positives = 109/265 (41%), Gaps = 7/265 (2%)
Query: 76 DGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRV 135
D L++W ++ + V ++PSG+ +A G D I+ + +G V
Sbjct: 2 DSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTV 60
Query: 136 SRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 194
R HT + F D Q VT+S D T +W + + + H V +P
Sbjct: 61 FR---AHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSP 117
Query: 195 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 254
D RL VS + D + KLWD C ++ H + + F P+G A D T +++D
Sbjct: 118 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 177
Query: 255 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR 314
+R + L Y + + +SF SG L+ D + D ++ L GH
Sbjct: 178 VRTHRLLQHYQLHS--AAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGP 235
Query: 315 VSCLGVTDDGMAVATGSWDSFLKIW 339
+ + + G A+G D + +W
Sbjct: 236 ATTVAFSRTGEYFASGGSDEQVMVW 260
Score = 90.5 bits (223), Expect = 2e-18
Identities = 60/247 (24%), Positives = 106/247 (42%), Gaps = 9/247 (3%)
Query: 53 GHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYV 112
GH + +++ LL S S+D + IW + ++ V + + G
Sbjct: 21 GHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSF 80
Query: 113 ACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDI 171
D ++ ++ +S+ H ++ C +F D + IV++S D T LWD
Sbjct: 81 VTASDDKTVKVWATHRQKFLFSLSQ----HINWVRCAKFSPDGRLIVSASDDKTVKLWDK 136
Query: 172 ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINA 231
+ + ++ H G V + P + D + K+WDVR Q + H + +N
Sbjct: 137 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 196
Query: 232 ICFFPNGNAFATGSDDATCRLFDLRADQELMT-YSHDNIICGITSVSFSKSGRLLLAGYD 290
+ F P+GN T S D+T ++ DL + L T + H T+V+FS++G +G
Sbjct: 197 LSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQG---PATTVAFSRTGEYFASGGS 253
Query: 291 DFNCNVW 297
D VW
Sbjct: 254 DEQVMVW 260
Score = 85.1 bits (209), Expect = 8e-17
Identities = 45/197 (22%), Positives = 88/197 (44%), Gaps = 5/197 (2%)
Query: 52 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 111
R H A + ++H+ +D + V+AS D + +W ++ + ++ +WV ++P G
Sbjct: 62 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRL 121
Query: 112 VACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG-DTTCALWD 170
+ D +++ +RE H G+++ F + ++G D T +WD
Sbjct: 122 IVSASDDKTVKLWDKSSRE----CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 177
Query: 171 IETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN 230
+ T + + H+ V LS P ++ + D++ K+ D+ EG T GH+
Sbjct: 178 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPAT 237
Query: 231 AICFFPNGNAFATGSDD 247
+ F G FA+G D
Sbjct: 238 TVAFSRTGEYFASGGSD 254
Score = 76.6 bits (187), Expect = 3e-14
Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 2/178 (1%)
Query: 163 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
D+ +W ++ + FTGH V ++ +P L SG+ D + ++W F
Sbjct: 2 DSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVF 61
Query: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSG 282
H + + ++ F +G +F T SDD T +++ + L + S I + FS G
Sbjct: 62 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQH--INWVRCAKFSPDG 119
Query: 283 RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
RL+++ DD +WD + H V+ + G +A D+ +K+W+
Sbjct: 120 RLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 177
Score = 73.2 bits (178), Expect = 3e-13
Identities = 42/163 (25%), Positives = 77/163 (47%), Gaps = 5/163 (3%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
+L H+ + + D RL+VSAS D + +WD + VH+ +V + PSG
Sbjct: 102 SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSG 161
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRF-LDDNQIVTSSGDTTCAL 168
+A G+DN +++++T R+ + H+ ++ F N ++T+S D+T +
Sbjct: 162 TCIAAAGMDNTVKVWDVRTH----RLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKI 217
Query: 169 WDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 211
D+ G+ T GH G +++ + F SG D +W
Sbjct: 218 LDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 260
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 94.4 bits (233), Expect = 1e-19
Identities = 80/317 (25%), Positives = 138/317 (43%), Gaps = 38/317 (11%)
Query: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD------SYTTNKVHAIPLRSSW----- 99
LRGH ++++ W S LL S S D IW+ S +T V +R
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 100 ---VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQ 156
V + + G +A G D I+ T++GN+ + L H G + ++
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW---TKDGNL--ASTLGQHKGPIFALKWNKKGN 279
Query: 157 IVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVRE 215
+ S+G D T +WD TG+ F H+ + + + F S + D + + +
Sbjct: 280 FILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQ 338
Query: 216 GMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ---ELMTYSHDNIICG 272
+TF GH +++NAI + P GN A+ SDD T +++ ++ D +L ++ +
Sbjct: 339 DRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKE----- 393
Query: 273 ITSVSFSKSG--------RLLLAGYD-DFNCNVWDALKADRAGVLAGHDNRVSCLGVTDD 323
I ++ +S +G L+LA D +WD + L H V + + D
Sbjct: 394 IYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPD 453
Query: 324 GMAVATGSWDSFLKIWN 340
G +A+GS+D + IWN
Sbjct: 454 GRYLASGSFDKCVHIWN 470
Score = 85.5 bits (210), Expect = 6e-17
Identities = 58/264 (21%), Positives = 111/264 (42%), Gaps = 22/264 (8%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
TL H I+A+ W ++SA D IIWD++T P S+ + + +
Sbjct: 261 TLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNN 320
Query: 110 NYVACGG--LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTS-SGDTTC 166
+ +C ++C + G R + GHT ++ ++ ++ S S D T
Sbjct: 321 TFASCSTDMCIHVCKL-------GQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTL 373
Query: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPD---------TRLFVSGACDASAKLWDVREGM 217
+W ++ H ++ ++ +P + S + D++ +LWDV G+
Sbjct: 374 KIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGI 433
Query: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
C T T H+ + ++ F P+G A+GS D +++ + + +Y GI V
Sbjct: 434 CIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTG---GIFEVC 490
Query: 278 FSKSGRLLLAGYDDFNCNVWDALK 301
++ +G + A D + V D K
Sbjct: 491 WNAAGDKVGASASDGSVCVLDLRK 514
Score = 71.6 bits (174), Expect = 9e-13
Identities = 51/213 (23%), Positives = 84/213 (39%), Gaps = 37/213 (17%)
Query: 44 QMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 103
Q R +T +GH ++ A+ W LL S S D L IW N VH + + + T
Sbjct: 338 QDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTI 397
Query: 104 AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD 163
++P+G T N + + ++S D
Sbjct: 398 KWSPTGP----------------GTNNPNANL--------------------MLASASFD 421
Query: 164 TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 223
+T LWD++ G T T H V S++ +PD R SG+ D +W+ + G ++
Sbjct: 422 STVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYR 481
Query: 224 GHESDINAICFFPNGNAFATGSDDATCRLFDLR 256
G I +C+ G+ + D + + DLR
Sbjct: 482 G-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 513
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 92.0 bits (227), Expect = 7e-19
Identities = 48/188 (25%), Positives = 82/188 (43%)
Query: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
D N+I+T D ++D + Q T GHT V S+ P L S + DA+ ++W
Sbjct: 233 DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWS 292
Query: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
V C Q HES + + G+ + SDD D++ + L + + C
Sbjct: 293 VPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCS 352
Query: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
+T F G + G D +WD + GH ++ + +++G +AT +
Sbjct: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412
Query: 333 DSFLKIWN 340
DS +K+W+
Sbjct: 413 DSSVKLWD 420
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/254 (26%), Positives = 103/254 (40%), Gaps = 53/254 (20%)
Query: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
TL+GH K+ ++ + L+ SAS D + IW + V + S V + +G
Sbjct: 259 TLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATG 318
Query: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 169
+Y +++SS D A
Sbjct: 319 DY---------------------------------------------LLSSSDDQYWAFS 333
Query: 170 DIETGQQTTTFTGHTGDVMSLSLA---PDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
DI+TG+ T T T SL+ A PD +F +G D+ K+WD++E F GH
Sbjct: 334 DIQTGRVLTKVTDETSGC-SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHS 392
Query: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
I +I F NG AT +DD++ +L+DLR + T DN + S+ F +SG L
Sbjct: 393 GPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNF-EVKSLIFDQSGTYLA 451
Query: 287 AGYDD---FNCNVW 297
G D + C W
Sbjct: 452 LGGTDVQIYICKQW 465
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.133 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,470,612
Number of Sequences: 37866
Number of extensions: 519127
Number of successful extensions: 4590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 240
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 1368
Number of HSP's gapped (non-prelim): 1527
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.