Search of human proteins with 112789532

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112789532 poliovirus receptor related 2 isoform delta
precursor [Homo sapiens]
         (538 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112789532 poliovirus receptor related 2 isoform delta precurs...  1087   0.0  
gi|5360210 poliovirus receptor related 2 isoform alpha precursor...   719   0.0  
gi|209413732 poliovirus receptor isoform delta [Homo sapiens]         336   4e-92
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]         336   4e-92
gi|209413728 poliovirus receptor isoform beta [Homo sapiens]          334   1e-91
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]         333   2e-91
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]    208   1e-53
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]    197   2e-50
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]    182   5e-46
gi|11386199 poliovirus receptor-related 3 [Homo sapiens]              159   6e-39
gi|222136611 poliovirus receptor-related 4 [Homo sapiens]             124   3e-28
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]       89   8e-18
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho...    89   1e-17
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho...    87   5e-17
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]         83   7e-16
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]          83   7e-16
gi|21686977 cell adhesion molecule 4 [Homo sapiens]                    71   2e-12
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]               65   2e-10
gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens]               65   2e-10
gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]               60   4e-09
gi|98986445 carcinoembryonic antigen-related cell adhesion molec...    59   1e-08
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho...    55   2e-07
gi|90903245 CD200 antigen isoform b [Homo sapiens]                     55   2e-07
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]           55   2e-07
gi|118572606 hemicentin 1 [Homo sapiens]                               54   4e-07
gi|157739930 TAP binding protein-like [Homo sapiens]                   53   6e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    53   8e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    53   8e-07
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    53   8e-07
gi|45594240 limbic system-associated membrane protein [Homo sapi...    52   2e-06

>gi|112789532 poliovirus receptor related 2 isoform delta precursor
           [Homo sapiens]
          Length = 538

 Score = 1087 bits (2811), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV 60
           MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
Sbjct: 1   MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV 60

Query: 61  PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL 120
           PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
Sbjct: 61  PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL 120

Query: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV 180
           QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
Sbjct: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV 180

Query: 181 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240
           ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
Sbjct: 181 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240

Query: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS 300
           EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
Sbjct: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS 300

Query: 301 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG 360
           GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG
Sbjct: 301 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGG 360

Query: 361 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM 420
           IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM
Sbjct: 361 IIGGIIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEM 420

Query: 421 PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV 480
           PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV
Sbjct: 421 PSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPV 480

Query: 481 PPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFVMSRAMYV 538
           PPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFVMSRAMYV
Sbjct: 481 PPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFVMSRAMYV 538


>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
           [Homo sapiens]
          Length = 479

 Score =  719 bits (1857), Expect = 0.0
 Identities = 358/397 (90%), Positives = 370/397 (93%), Gaps = 3/397 (0%)

Query: 1   MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV 60
           MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV
Sbjct: 1   MARAAALLPSRSPPTPLLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPV 60

Query: 61  PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL 120
           PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL
Sbjct: 61  PGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAEL 120

Query: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV 180
           QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV
Sbjct: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV 180

Query: 181 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240
           ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV
Sbjct: 181 ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240

Query: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS 300
           EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS
Sbjct: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS 300

Query: 301 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGA--- 357
           GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP  +       
Sbjct: 301 GTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPL 360

Query: 358 TGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQGA 394
             G +GG +  ++  A  +   ++ R +R+ ++  GA
Sbjct: 361 VWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGA 397



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 8/67 (11%)

Query: 475 GSPI---PVPPGPPAVEDVSLDLEDEEGEEEEEYLDKINPIYDALSYSSPSDSYQGKGFV 531
           G P+   PV PGP     +  D +DEE EEEEE  +K   +    +     +S      +
Sbjct: 418 GDPVFWTPVVPGP-----MEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLI 472

Query: 532 MSRAMYV 538
             RA+YV
Sbjct: 473 SRRAVYV 479


>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
          Length = 392

 Score =  336 bits (861), Expect = 4e-92
 Identities = 182/358 (50%), Positives = 235/358 (65%), Gaps = 19/358 (5%)

Query: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68

Query: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235

Query: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295

Query: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGIIGGIIAAII 370
           QL+I  VD   NTT +C VTNA+G  +AE  + V+E P +  +G +   I  ++  I+
Sbjct: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGIL 353


>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
          Length = 417

 Score =  336 bits (861), Expect = 4e-92
 Identities = 182/358 (50%), Positives = 235/358 (65%), Gaps = 19/358 (5%)

Query: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68

Query: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235

Query: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295

Query: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGIIGGIIAAII 370
           QL+I  VD   NTT +C VTNA+G  +AE  + V+E P +  +G +   I  ++  I+
Sbjct: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGIL 353


>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
          Length = 372

 Score =  334 bits (857), Expect = 1e-91
 Identities = 180/344 (52%), Positives = 229/344 (66%), Gaps = 19/344 (5%)

Query: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68

Query: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235

Query: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295

Query: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAG 356
           QL+I  VD   NTT +C VTNA+G  +AE  + V+E P +  +G
Sbjct: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG 339


>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
          Length = 364

 Score =  333 bits (854), Expect = 2e-91
 Identities = 182/349 (52%), Positives = 231/349 (66%), Gaps = 20/349 (5%)

Query: 19  WPLLLLLLL-----ETGAQDVRVQVLPEVRGQLGGTVELPCHL-LPPVPGLYISLVTWQR 72
           WPLLL+ LL       G  DV VQ   +V G LG +V LPC+L +P +   ++S +TW R
Sbjct: 9   WPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWAR 68

Query: 73  PDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTV 132
                +   +A FH   GPS+      S+RL FV+A+        AEL++A+L + GL V
Sbjct: 69  HGESGS---MAVFHQTQGPSYSE----SKRLEFVAARLG------AELRNASLRMFGLRV 115

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEGNYTC F TFP+GS     WLRV+AKP+N AE QKV  + +P  +A C+S  GRPPA
Sbjct: 116 EDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPA 175

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIP 252
           +I+W S L      +QV G L+GTVTVTS + LVPS + DG  VTCKVEHESFE+P L+ 
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235

Query: 253 VTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGS 312
           V L+V YPPEVSISGYD+NWYLG+ +ATL+CD RSNPEPTGY+WSTT G  P  AVAQG+
Sbjct: 236 VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGA 295

Query: 313 QLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGI 361
           QL+I  VD   NTT +C VTNA+G  +AE  + V+ T + A A A G +
Sbjct: 296 QLLIRPVDKPINTTLICNVTNALGARQAELTVQVKGTEH-ASASANGHV 343


>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
          Length = 458

 Score =  208 bits (529), Expect = 1e-53
 Identities = 145/444 (32%), Positives = 209/444 (47%), Gaps = 43/444 (9%)

Query: 30  GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89
           G     VQV   + G +G  V L C    P+P + I+ VTWQ+     + QNVA ++P M
Sbjct: 27  GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85

Query: 90  GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149
           G S  +P    ER+ F+               D T+ L  L +EDEG Y CEFATFP G+
Sbjct: 86  GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133

Query: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204
                 L V+AKP N  E  +          D   VA C S  G+PP+ +SW + L  EA
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193

Query: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262
           +  ++     GTVTV SR+ LVPS  A   ++ C V +  + F+E     +TL+V+Y PE
Sbjct: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248

Query: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321
           V+I G+D NWYL R D  L+C   +NP  T Y W+T +G+ P    AQ   L     ++ 
Sbjct: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308

Query: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETPN-TAGAGATGGIIGGIIAA-IIATAVAATGI 379
               T++C  TN +G    +  + + E P    G G+   ++ G +A  +I  AV     
Sbjct: 309 SLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLGSAARLLAGTVAVFLILVAVLTVFF 368

Query: 380 LICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQLFTLGASEHS------ 433
           L  RQQ+      GA  D+ L   P    P+ ++ L  +++       G  +        
Sbjct: 369 LYNRQQKSPPETDGAGTDQPLSQKPE-PSPSRQSSLVPEDIQVVHLDPGRQQQQEEEDLQ 427

Query: 434 --PLKTPYFDAGASCTEQEMPRYH 455
              L+ PY+D G S      P YH
Sbjct: 428 KLSLQPPYYDLGVS------PSYH 445


>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
          Length = 517

 Score =  197 bits (501), Expect = 2e-50
 Identities = 127/374 (33%), Positives = 184/374 (49%), Gaps = 34/374 (9%)

Query: 30  GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89
           G     VQV   + G +G  V L C    P+P + I+ VTWQ+     + QNVA ++P M
Sbjct: 27  GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85

Query: 90  GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149
           G S  +P    ER+ F+               D T+ L  L +EDEG Y CEFATFP G+
Sbjct: 86  GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133

Query: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204
                 L V+AKP N  E  +          D   VA C S  G+PP+ +SW + L  EA
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193

Query: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262
           +  ++     GTVTV SR+ LVPS  A   ++ C V +  + F+E     +TL+V+Y PE
Sbjct: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248

Query: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321
           V+I G+D NWYL R D  L+C   +NP  T Y W+T +G+ P    AQ   L     ++ 
Sbjct: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308

Query: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATG--------GIIGGIIAAIIATA 373
               T++C  TN +G    +  + + E P T      G         IIGG+  +I+   
Sbjct: 309 SLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVL 368

Query: 374 VAATGILICRQQRK 387
           +   GI++  ++R+
Sbjct: 369 IVVGGIVVALRRRR 382


>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
          Length = 352

 Score =  182 bits (463), Expect = 5e-46
 Identities = 115/315 (36%), Positives = 160/315 (50%), Gaps = 26/315 (8%)

Query: 30  GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89
           G     VQV   + G +G  V L C    P+P + I+ VTWQ+     + QNVA ++P M
Sbjct: 27  GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85

Query: 90  GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149
           G S  +P    ER+ F+               D T+ L  L +EDEG Y CEFATFP G+
Sbjct: 86  GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133

Query: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204
                 L V+AKP N  E  +          D   VA C S  G+PP+ +SW + L  EA
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193

Query: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262
           +  ++     GTVTV SR+ LVPS  A   ++ C V +  + F+E     +TL+V+Y PE
Sbjct: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248

Query: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321
           V+I G+D NWYL R D  L+C   +NP  T Y W+T +G+ P    AQ   L     ++ 
Sbjct: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308

Query: 322 LFNTTFVCTVTNAVG 336
               T++C  TN +G
Sbjct: 309 SLAGTYICEATNPIG 323


>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
          Length = 549

 Score =  159 bits (402), Expect = 6e-39
 Identities = 106/348 (30%), Positives = 166/348 (47%), Gaps = 27/348 (7%)

Query: 13  PPTP-----LLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISL 67
           PPTP     LL+PLLL   L  GA    + V P V    G  V L C +        I+ 
Sbjct: 33  PPTPPPLLLLLFPLLLFSRL-CGALAGPIIVEPHVTAVWGKNVSLKCLI---EVNETITQ 88

Query: 68  VTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLAL 127
           ++W++    ++ Q VA  HP+ G S      G  R+ F +            L DAT+ L
Sbjct: 89  ISWEKIHGKSS-QTVAVHHPQYGFSVQGEYQG--RVLFKNYS----------LNDATITL 135

Query: 128 HGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQA--EAQKVTFSQDPTTVALCIS 185
           H +   D G Y C+  TFP G+ +  T + V+ +P          +    + T  A+CI+
Sbjct: 136 HNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIA 195

Query: 186 KEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESF 245
             G+P A I W   L     E+  +     T T+ S++ L P+  A G  +TC V+H + 
Sbjct: 196 ATGKPVAHIDWEGDLG--EMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPAL 253

Query: 246 EEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPT 305
           E+       L ++Y PEVS++GYD NW++GR    L C+  +NP P    WS   G +P 
Sbjct: 254 EKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPD 313

Query: 306 SAVAQGSQL-VIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNT 352
             +A  + L  +H +   ++  ++C VTN++G    ++VI++ + P T
Sbjct: 314 GLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTT 361


>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
          Length = 510

 Score =  124 bits (310), Expect = 3e-28
 Identities = 121/467 (25%), Positives = 179/467 (38%), Gaps = 45/467 (9%)

Query: 16  PLLWPLLLLLLLE-TGAQDV-RVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRP 73
           P  W LLLLLL   TG      ++    V   LG   +LPC       G  +  V W R 
Sbjct: 12  PEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SGEQVGQVAWARV 70

Query: 74  DAPANHQNVAAFHPKMG----PSFPS----PKPGSERLSFVSAKQSTGQDTEAELQDATL 125
           DA    Q +A  H K G    P++      P P    L                  D ++
Sbjct: 71  DAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPL------------------DGSV 112

Query: 126 ALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCIS 185
            L      DEG Y C  +TFP GS +    LRV+  P                T+A   +
Sbjct: 113 LLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCT 172

Query: 186 KEGRPPARISWLSSLDWEAKETQVSGTL--AGTVTVTSRFTLVPSGRADGVTVTCKVEHE 243
            EG P   ++W    D E K T  S +   + +  VTS F LVPS   +G  +TC V H 
Sbjct: 173 AEGSPAPSVTW----DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228

Query: 244 SFEEPALIPVTLSVRYPPEVSISGYDDN--WYLGRTDATLSCDVRSNPEPTGYDWSTTSG 301
              +   I   L V +  E S+ G +D   W++GR  A L C     P P+ Y+W+   G
Sbjct: 229 GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDG 287

Query: 302 TFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAG----A 357
             P+     G  L    + +  +  +VC V+N      ++  + V +    +G      +
Sbjct: 288 PLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVS 347

Query: 358 TGGIIGGIIAAIIATAVAATGILICRQQRK--EQTLQGAEEDEDLEGPPSYKPPTPKAKL 415
              ++ G+IAA++   +    +L+ R  R+  +Q  Q  EE+  L    S +        
Sbjct: 348 ASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIR-RLHSHHT 406

Query: 416 EAQEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEE 462
           + +  P +   L A  H               E E   Y  L T+ E
Sbjct: 407 DPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVRE 453


>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
          Length = 437

 Score = 89.4 bits (220), Expect = 8e-18
 Identities = 76/267 (28%), Positives = 112/267 (41%), Gaps = 14/267 (5%)

Query: 118 AELQDATLALHGLTVEDEGNYTCEFATFP-KGSVRGMTWLRVIAKPKNQAEAQKVTFSQD 176
           A   + ++++  +++ DEG YTC   T P K S   +T L V  KP+    +  V   + 
Sbjct: 84  ASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM--EG 141

Query: 177 PTTVALCISKEGRPPARISWLSSLDWEAKETQV---SGTLAGTVTVTSRFTLVPSGRADG 233
                 C +   +P A I W  + D E K+ +          T TV+S          DG
Sbjct: 142 DLMQLTCKTSGSKPAADIRWFKN-DKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDG 200

Query: 234 VTVTCKVEHESFEE-PALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT 292
           V V C+V+HES    P +    L + Y P V I         G+    L+C+ +  P P 
Sbjct: 201 VAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQP-LILTCESKGKPLPE 259

Query: 293 GYDWSTTSGTFPTS--AVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
              W+   G  P     V  G +L I  ++   N T+ C  TN +G   AE V+ V + P
Sbjct: 260 PVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVP 319

Query: 351 NTAGAGATGGIIGGIIAAIIATAVAAT 377
           NT        II  +  A + T VA T
Sbjct: 320 NTL---LPTTIIPSLTTATVTTTVAIT 343


>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 73/276 (26%), Positives = 113/276 (40%), Gaps = 17/276 (6%)

Query: 105 FVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKN 164
           F   K S  Q       +  ++L  +++ DEG Y C+  T P       T + V+  P+N
Sbjct: 89  FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQE--SYTTITVLVPPRN 146

Query: 165 -QAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRF 223
              + QK T  +       C +   +P   I W    + E K        +   TVTS+ 
Sbjct: 147 LMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQL 205

Query: 224 TLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDAT-L 281
            L      DGV V C+VEH +          L V+Y P+V I   Y         DA  L
Sbjct: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALEL 265

Query: 282 SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
           +C+    P+P    W       P  AV  G  L I+ ++   N T+ C  +N VG   ++
Sbjct: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325

Query: 342 QVIFVRETPNTAGAGATGGI-------IGGIIAAII 370
            +++V +    + AG  G I       IGG++A ++
Sbjct: 326 YMLYVYD----SRAGEEGSIRAVDHAVIGGVVAVVV 357


>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 67/251 (26%), Positives = 102/251 (40%), Gaps = 6/251 (2%)

Query: 105 FVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKN 164
           F   K S  Q       +  ++L  +++ DEG Y C+  T P       T + V+  P+N
Sbjct: 89  FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQE--SYTTITVLVPPRN 146

Query: 165 -QAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRF 223
              + QK T  +       C +   +P   I W    + E K        +   TVTS+ 
Sbjct: 147 LMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQL 205

Query: 224 TLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDAT-L 281
            L      DGV V C+VEH +          L V+Y P+V I   Y         DA  L
Sbjct: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALEL 265

Query: 282 SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
           +C+    P+P    W       P  AV  G  L I+ ++   N T+ C  +N VG   ++
Sbjct: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325

Query: 342 QVIFVRETPNT 352
            +++V + P T
Sbjct: 326 YMLYVYDPPTT 336


>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
          Length = 398

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 67/254 (26%), Positives = 113/254 (44%), Gaps = 9/254 (3%)

Query: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGM-TWLRVIAKPKNQAEAQKVTFSQDPTTV 180
           + ++++  + + DEG YTC   T P  + + + T L +  KP       K +  +  T  
Sbjct: 92  ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYKSSLREKDTAT 149

Query: 181 ALCISKEGRPPARISWLSS-LDWEAKETQVSGTLAG-TVTVTSRFTLVPSGRADGVTVTC 238
             C S   +P AR++W     +   + T++     G T TV+S  T   +   DG ++ C
Sbjct: 150 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 209

Query: 239 KVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            V HES +         + V Y P   I     +   G+    L C+ R NP P  Y W 
Sbjct: 210 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWE 268

Query: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE-TPNTAGAG 356
              G+ P   + Q S L+   ++   + T+ CT T+ +G  +A   + V + +P  + + 
Sbjct: 269 -KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 327

Query: 357 ATGGIIGGIIAAII 370
               IIGGI+A I+
Sbjct: 328 TYHAIIGGIVAFIV 341


>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
          Length = 432

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 67/254 (26%), Positives = 113/254 (44%), Gaps = 9/254 (3%)

Query: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGM-TWLRVIAKPKNQAEAQKVTFSQDPTTV 180
           + ++++  + + DEG YTC   T P  + + + T L +  KP       K +  +  T  
Sbjct: 126 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYKSSLREKDTAT 183

Query: 181 ALCISKEGRPPARISWLSS-LDWEAKETQVSGTLAG-TVTVTSRFTLVPSGRADGVTVTC 238
             C S   +P AR++W     +   + T++     G T TV+S  T   +   DG ++ C
Sbjct: 184 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 243

Query: 239 KVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            V HES +         + V Y P   I     +   G+    L C+ R NP P  Y W 
Sbjct: 244 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWE 302

Query: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE-TPNTAGAG 356
              G+ P   + Q S L+   ++   + T+ CT T+ +G  +A   + V + +P  + + 
Sbjct: 303 -KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 361

Query: 357 ATGGIIGGIIAAII 370
               IIGGI+A I+
Sbjct: 362 TYHAIIGGIVAFIV 375


>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
          Length = 388

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 90/396 (22%), Positives = 137/396 (34%), Gaps = 49/396 (12%)

Query: 19  WPLLLLLLLETG---AQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDA 75
           WPLLLL     G    Q+V+ +    V    GG  E+ C L                   
Sbjct: 9   WPLLLLWAAAAGPGAGQEVQTE---NVTVAEGGVAEITCRL------------------- 46

Query: 76  PANHQNVAAFHPKMGPSFPSPKPGSERLSFVSA---KQSTGQDTEAELQDATLALHGLTV 132
                     H   G       P  + L F      K    Q  E   +   + L    +
Sbjct: 47  ----------HQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARL 96

Query: 133 EDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPA 192
           EDEG Y C+  T  + +   +  L V+  P+N     +    +       C+    RP A
Sbjct: 97  EDEGGYFCQLYT--EDTHHQIATLTVLVAPENPVVEVREQAVEGGEVELSCLVPRSRPAA 154

Query: 193 RISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEE--PAL 250
            + W      E K    S       +V S        + DG  + C+ ++++        
Sbjct: 155 TLRWYRDRK-ELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQ 213

Query: 251 IPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQ 310
               L V+Y P   I         G T   L+C V  NP P    W+  + + P  A A 
Sbjct: 214 TQYVLDVQYSPTARIHASQAVVREGDT-LVLTCAVTGNPRPNQIRWNRGNESLPERAEAV 272

Query: 311 GSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATG---GIIGGIIA 367
           G  L +  + S  N T+ C  +N  G  RA  V+ V + P       T     I+GGI+A
Sbjct: 273 GETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYD-PGAVVEAQTSVPYAIVGGILA 331

Query: 368 AIIATAVAA-TGILICRQQRKEQTLQGAEEDEDLEG 402
            ++   +    G++ C  ++K   L       D +G
Sbjct: 332 LLVFLIICVLVGMVWCSVRQKGSYLTHEASGLDEQG 367


>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
          Length = 708

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 88/332 (26%), Positives = 124/332 (37%), Gaps = 55/332 (16%)

Query: 20  PLLLLLLL----ETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDA 75
           P LL+LL       G     +Q   ++   LG    LPC L     G Y  LV W +   
Sbjct: 7   PALLVLLFCFRGRAGPSPHFLQQPEDLVVLLGEEARLPCAL-----GAYWGLVQWTKSGL 61

Query: 76  PANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDE 135
               Q                 PG  R  ++S   + GQ          L +  + +EDE
Sbjct: 62  ALGGQR--------------DLPGWSRY-WISGNAANGQHD--------LHIRPVELEDE 98

Query: 136 GNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA------LCISK-EG 188
            +Y C+      G       L V+  P    EA +V      + VA       C S+ + 
Sbjct: 99  ASYECQATQ--AGLRSRPAQLHVLVPP----EAPQVLGGPSVSLVAGVPANLTCRSRGDA 152

Query: 189 RPPARISWLSS---LDWEA-KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHES 244
           RP   + W      LD     +T +     G+V  T   TL P    DG T  C+   ++
Sbjct: 153 RPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVEST--LTLTPFSHDDGATFVCRARSQA 210

Query: 245 FEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFP 304
                   +TLS++YPPEV++S        G     L C   + P  TGY W+   G  P
Sbjct: 211 LPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFL-CQATAQPPVTGYRWA--KGGSP 267

Query: 305 TSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
               A+G +L + A  S       C V+NAVG
Sbjct: 268 VLG-ARGPRLEVVADASFLTEPVSCEVSNAVG 298



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 85/370 (22%), Positives = 136/370 (36%), Gaps = 54/370 (14%)

Query: 148 GSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKET 207
           GS    T L V+  P  QA+ + V+          C  + G P  R++W           
Sbjct: 298 GSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWR-GNPLPRVTWTRR-------- 348

Query: 208 QVSGTLAGTVTVTSRFTL-VPS-GRADGVTVTCKVEHE-SFEEPALIPVTLSVRYPPEVS 264
                  G   + S  TL +PS G  D     C+ E   S          L+V  PP V+
Sbjct: 349 ------GGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT 402

Query: 265 ISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSG-------------TFPT----SA 307
                  +  G   A L C V ++P P    WS   G             TFP       
Sbjct: 403 ALHSAPAFLRG--PARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGG 460

Query: 308 VAQGSQLVIH---AVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGIIGG 364
           +  G   V+H     +S F+ +F C+  N +G G A+  +  R+   T        I+ G
Sbjct: 461 LGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASLGRRDLLPTV------RIVAG 514

Query: 365 IIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQ- 423
           + AA     +  TG+ +C  +  + +   +E+   +  P S    + +   E +E  S+ 
Sbjct: 515 VAAATTTLLMVITGVALCCWRHSKASASFSEQKNLMRIPGSSDGSSSRGP-EEEETGSRE 573

Query: 424 -LFTLGASEHSPLKTPYFDAGASCTEQEMPRYHEL--PTLEERSGPLHPGATSLGSPIPV 480
               +  ++HS L     + G   T+     Y+++   ++    G    G   L  P P+
Sbjct: 574 DRGPIVHTDHSDLVLE--EKGTLETKDPTNGYYKVRGVSVSLSLGEAPGGGLFLPPPSPL 631

Query: 481 -PPGPPAVED 489
            PPG P   D
Sbjct: 632 GPPGTPTFYD 641


>gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens]
          Length = 633

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 88/332 (26%), Positives = 124/332 (37%), Gaps = 55/332 (16%)

Query: 20  PLLLLLLL----ETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDA 75
           P LL+LL       G     +Q   ++   LG    LPC L     G Y  LV W +   
Sbjct: 7   PALLVLLFCFRGRAGPSPHFLQQPEDLVVLLGEEARLPCAL-----GAYWGLVQWTKSGL 61

Query: 76  PANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDE 135
               Q                 PG  R  ++S   + GQ          L +  + +EDE
Sbjct: 62  ALGGQR--------------DLPGWSRY-WISGNAANGQHD--------LHIRPVELEDE 98

Query: 136 GNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA------LCISK-EG 188
            +Y C+      G       L V+  P    EA +V      + VA       C S+ + 
Sbjct: 99  ASYECQATQ--AGLRSRPAQLHVLVPP----EAPQVLGGPSVSLVAGVPANLTCRSRGDA 152

Query: 189 RPPARISWLSS---LDWEA-KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHES 244
           RP   + W      LD     +T +     G+V  T   TL P    DG T  C+   ++
Sbjct: 153 RPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVEST--LTLTPFSHDDGATFVCRARSQA 210

Query: 245 FEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFP 304
                   +TLS++YPPEV++S        G     L C   + P  TGY W+   G  P
Sbjct: 211 LPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFL-CQATAQPPVTGYRWA--KGGSP 267

Query: 305 TSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
               A+G +L + A  S       C V+NAVG
Sbjct: 268 VLG-ARGPRLEVVADASFLTEPVSCEVSNAVG 298



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 66/281 (23%), Positives = 102/281 (36%), Gaps = 46/281 (16%)

Query: 148 GSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKET 207
           GS    T L V+  P  QA+ + V+          C  + G P  R++W           
Sbjct: 298 GSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWR-GNPLPRVTWTRR-------- 348

Query: 208 QVSGTLAGTVTVTSRFTL-VPS-GRADGVTVTCKVEHE-SFEEPALIPVTLSVRYPPEVS 264
                  G   + S  TL +PS G  D     C+ E   S          L+V  PP V+
Sbjct: 349 ------GGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT 402

Query: 265 ISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSG-------------TFPT----SA 307
                  +  G   A L C V ++P P    WS   G             TFP       
Sbjct: 403 ALHSAPAFLRG--PARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGG 460

Query: 308 VAQGSQLVIH---AVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGIIGG 364
           +  G   V+H     +S F+ +F C+  N +G G A+  +  R+   T        I+ G
Sbjct: 461 LGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASLGRRDLLPTV------RIVAG 514

Query: 365 IIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPS 405
           + AA     +  TG+ +C  +  + +   +E+   +  P S
Sbjct: 515 VAAATTTLLMVITGVALCCWRHSKASASFSEQKNLMRIPGS 555


>gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]
          Length = 583

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 63/223 (28%), Positives = 91/223 (40%), Gaps = 23/223 (10%)

Query: 125 LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA--- 181
           L +  + +EDE +Y C+      G       L V+  P    EA +V      + VA   
Sbjct: 38  LHIRPVELEDEASYECQATQ--AGLRSRPAQLHVLVPP----EAPQVLGGPSVSLVAGVP 91

Query: 182 ---LCISK-EGRPPARISWLSS---LDWEA-KETQVSGTLAGTVTVTSRFTLVPSGRADG 233
               C S+ + RP   + W      LD     +T +     G+V  T   TL P    DG
Sbjct: 92  ANLTCRSRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVEST--LTLTPFSHDDG 149

Query: 234 VTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTG 293
            T  C+   ++        +TLS++YPPEV++S        G     L C   + P  TG
Sbjct: 150 ATFVCRARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFL-CQATAQPPVTG 208

Query: 294 YDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
           Y W+   G  P    A+G +L + A  S       C V+NAVG
Sbjct: 209 YRWA--KGGSPVLG-ARGPRLEVVADASFLTEPVSCEVSNAVG 248



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 66/281 (23%), Positives = 102/281 (36%), Gaps = 46/281 (16%)

Query: 148 GSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKET 207
           GS    T L V+  P  QA+ + V+          C  + G P  R++W           
Sbjct: 248 GSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWR-GNPLPRVTWTRR-------- 298

Query: 208 QVSGTLAGTVTVTSRFTL-VPS-GRADGVTVTCKVEHE-SFEEPALIPVTLSVRYPPEVS 264
                  G   + S  TL +PS G  D     C+ E   S          L+V  PP V+
Sbjct: 299 ------GGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVT 352

Query: 265 ISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSG-------------TFPT----SA 307
                  +  G   A L C V ++P P    WS   G             TFP       
Sbjct: 353 ALHSAPAFLRG--PARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGG 410

Query: 308 VAQGSQLVIH---AVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGIIGG 364
           +  G   V+H     +S F+ +F C+  N +G G A+  +  R+   T        I+ G
Sbjct: 411 LGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASLGRRDLLPTV------RIVAG 464

Query: 365 IIAAIIATAVAATGILICRQQRKEQTLQGAEEDEDLEGPPS 405
           + AA     +  TG+ +C  +  + +   +E+   +  P S
Sbjct: 465 VAAATTTLLMVITGVALCCWRHSKASASFSEQKNLMRIPGS 505


>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 77/299 (25%), Positives = 117/299 (39%), Gaps = 33/299 (11%)

Query: 87  PKMGPSFPSPKPGSE-RLSFVSAKQSTGQ-----DTEAELQDATLALHGLTVEDEGNYTC 140
           P + PS+   +PG    LS  +A     Q     D   +     L +  +T ++ G YTC
Sbjct: 418 PTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTC 477

Query: 141 EFATFPKG----SVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISW 196
           +      G    +V+ +T    + KP   +   K    +D   VA     E +    + W
Sbjct: 478 QANNSASGHSRTTVKTITVSAELPKPSISSNNSKPV--EDKDAVAFTCEPEAQNTTYLWW 535

Query: 197 LSSLDWEAK-ETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTL 255
           ++          Q+S    G  T+T    L    R D     C +++ S       PVTL
Sbjct: 536 VNGQSLPVSPRLQLSN---GNRTLT----LFNVTRNDARAYVCGIQN-SVSANRSDPVTL 587

Query: 256 SVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLV 315
            V Y P+  I    D+ YL   +  LSC   SNP P  Y W         + V     L 
Sbjct: 588 DVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQ-YSWRINGIPQQHTQV-----LF 641

Query: 316 IHAVDSLFNTTFVCTVTNAVGMGRAEQV---IFVRETPNTAG--AGATGGIIGGIIAAI 369
           I  +    N T+ C V+N +  GR   +   I V  +  + G  AGAT GI+ G++  +
Sbjct: 642 IAKITPNNNGTYACFVSN-LATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGV 699



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 42/174 (24%), Positives = 66/174 (37%), Gaps = 10/174 (5%)

Query: 125 LALHGLTVEDEGNYTCEFATFPKGSVRG-MTWLRVIAKP-KNQAEAQKVTFSQDPTTVAL 182
           L +  +TV + G+YTC+      G  R  +T + V A+P K    +      +D   VAL
Sbjct: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVAL 343

Query: 183 CISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH 242
               E +    + W+++                T+T+ S           G+     V+H
Sbjct: 344 TCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDH 403

Query: 243 ESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW 296
                    PV L+V Y P+         +Y    + +LSC   SNP P  Y W
Sbjct: 404 SD-------PVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNP-PAQYSW 449



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 50/228 (21%), Positives = 85/228 (37%), Gaps = 27/228 (11%)

Query: 124 TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALC 183
           TL L  +T  D G Y C               L V+  P +   +   T+ +    ++L 
Sbjct: 377 TLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLS 436

Query: 184 ISKEGRPPARISWL--SSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVE 241
                 PPA+ SWL   ++    +E  +S     T   +  +T   +  A G + T    
Sbjct: 437 CHAASNPPAQYSWLIDGNIQQHTQELFISNI---TEKNSGLYTCQANNSASGHSRT---- 489

Query: 242 HESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSG 301
                   +  +T+S    P+ SIS  +      +     +C+  +  + T Y W     
Sbjct: 490 -------TVKTITVSAEL-PKPSISSNNSKPVEDKDAVAFTCEPEA--QNTTYLWWVNGQ 539

Query: 302 TFPTSAVAQGSQLVIHAVDSLFNTT------FVCTVTNAVGMGRAEQV 343
           + P S   Q S    +   +LFN T      +VC + N+V   R++ V
Sbjct: 540 SLPVSPRLQLSN--GNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPV 585



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 55/284 (19%), Positives = 91/284 (32%), Gaps = 47/284 (16%)

Query: 91  PSFPSPKPGSERLSFVSAKQSTGQDTEAELQDA------------------------TLA 126
           P  P P   S     V  K +     E E QDA                        TL 
Sbjct: 142 PELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLT 201

Query: 127 LHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISK 186
           L  +T  D  +Y CE              L V+  P     +   T  +    + L    
Sbjct: 202 LFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHA 261

Query: 187 EGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV-TVTCKVEHESF 245
              PPA+ SW                + GT   +++   +P+   +   + TC+  +   
Sbjct: 262 ASNPPAQYSWF---------------VNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDT 306

Query: 246 EEPALIPVTLSV-RYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFP 304
                   T++V   PP+  I+  + N         L+C+     + T Y W   + + P
Sbjct: 307 GLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCE--PEIQNTTYLWWVNNQSLP 364

Query: 305 TSAVAQGSQ----LVIHAVDSLFNTTFVCTVTNAVGMGRAEQVI 344
            S   Q S     L + +V       + C + N + +  ++ VI
Sbjct: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVI 408


>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
           sapiens]
          Length = 365

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 51/210 (24%), Positives = 88/210 (41%), Gaps = 14/210 (6%)

Query: 277 TDATLSCDVRSNPEPTGYDWSTTSGT--FPTSAVAQGSQLVIHA--VDSLFNTTFVCTVT 332
           +D  + C+ +    P  Y+W   S +   PTS +A+ +  VI      S ++ T+ CTV 
Sbjct: 156 SDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVR 215

Query: 333 NAVGMGRAEQVIFVRETPNTAGAGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQ 392
           N VG  +    + V    N AG      I G II  ++A A+    I  CR++R+E+  +
Sbjct: 216 NRVGSDQCLLRLNVVPPSNKAGL-----IAGAIIGTLLALALIGLIIFCCRKKRREEKYE 270

Query: 393 GAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMP 452
                +  E  P  K  T  A+       S L ++  S         ++   S   +  P
Sbjct: 271 KEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERTP 330

Query: 453 RYHELPTLEERSGPLHPGATSLGS-PIPVP 481
           +   LP  +  +    P  + +G+ P+ +P
Sbjct: 331 QSPTLPPAKVAA----PNLSRMGAIPVMIP 356


>gi|90903245 CD200 antigen isoform b [Homo sapiens]
          Length = 294

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 58/226 (25%), Positives = 85/226 (37%), Gaps = 25/226 (11%)

Query: 17  LLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAP 76
           L+W +  ++L     Q     V  + R QL     L C L      L   +VTWQ+  A 
Sbjct: 43  LVWVMAAVVLCTAQVQ----VVTQDEREQLYTPASLKCSLQNAQEAL---IVTWQKKKA- 94

Query: 77  ANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEG 136
            + +N+  F    G            +    A +     T+  LQ++T+    +T+EDEG
Sbjct: 95  VSPENMVTFSENHG------------VVIQPAYKDKINITQLGLQNSTITFWNITLEDEG 142

Query: 137 NYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISW 196
            Y C F TF  G + G   L V  +P     +    FS+D   +    S   RP   + W
Sbjct: 143 CYMCLFNTFGFGKISGTACLTVYVQP---IVSLHYKFSEDHLNIT--CSATARPAPMVFW 197

Query: 197 LSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH 242
                     T       GT +VTS   +       G  V C+V H
Sbjct: 198 KVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLH 243


>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
          Length = 269

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 58/226 (25%), Positives = 85/226 (37%), Gaps = 25/226 (11%)

Query: 17  LLWPLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAP 76
           L+W +  ++L     Q     V  + R QL     L C L      L   +VTWQ+  A 
Sbjct: 18  LVWVMAAVVLCTAQVQ----VVTQDEREQLYTPASLKCSLQNAQEAL---IVTWQKKKA- 69

Query: 77  ANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEG 136
            + +N+  F    G            +    A +     T+  LQ++T+    +T+EDEG
Sbjct: 70  VSPENMVTFSENHG------------VVIQPAYKDKINITQLGLQNSTITFWNITLEDEG 117

Query: 137 NYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISW 196
            Y C F TF  G + G   L V  +P     +    FS+D   +    S   RP   + W
Sbjct: 118 CYMCLFNTFGFGKISGTACLTVYVQP---IVSLHYKFSEDHLNIT--CSATARPAPMVFW 172

Query: 197 LSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH 242
                     T       GT +VTS   +       G  V C+V H
Sbjct: 173 KVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLH 218


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 58/240 (24%), Positives = 97/240 (40%), Gaps = 27/240 (11%)

Query: 120  LQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTT 179
            L   +L +  +   D G+YTC  A    GS    T L V   P+ ++     T +++   
Sbjct: 4128 LSSGSLQIAFVQPGDAGHYTCMAANVA-GSSSTSTKLTVHVPPRIRSTEGHYTVNENSQA 4186

Query: 180  VALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRA--DGVTVT 237
            +  C++ +G P   I+W        K+  +   L G  T      L+       D    T
Sbjct: 4187 ILPCVA-DGIPTPAINW-------KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYT 4238

Query: 238  CKVEHESFEEPALIPVTLSV-----RYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT 292
            C   + + E+   + +T+ V       P +VS++  +           LSC     P P 
Sbjct: 4239 CVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQ--------LRLSCKATGIPLPK 4290

Query: 293  GYDWSTTSGTFPT--SAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
               W+  +   P    +V   S+LVI  V    + T+VCT  N+VG  +A   ++V+E P
Sbjct: 4291 -LTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 58/235 (24%), Positives = 93/235 (39%), Gaps = 23/235 (9%)

Query: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA 181
           D TL +     +D G Y C  A+   G+ +  + LR I  PK      ++  +    TV 
Sbjct: 663 DGTLFIKNAAPKDAGIYGC-LASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVM 721

Query: 182 LCISKEGRPPARISWLSS-LDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240
            C    G PP ++ W    L+       +   L G + +     L      D    TC  
Sbjct: 722 EC-KTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDL------DAGDYTCVA 774

Query: 241 EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTT- 299
            +E+    A   +TL V  PP       D +  +G ++ TL C V+  PEPT   W    
Sbjct: 775 INEAGR--ATGKITLDVGSPPVFIQEPADVSMEIG-SNVTLPCYVQGYPEPT-IKWRRLD 830

Query: 300 -----SGTFPTSAVAQ---GSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFV 346
                S  F  S+++Q   G+  +++   S    T++C   N  G  ++E  + V
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWAS-DKGTYICEAENQFGKIQSETTVTV 884



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 66/283 (23%), Positives = 108/283 (38%), Gaps = 25/283 (8%)

Query: 93   FPSPKPGSERLSFV---SAKQSTGQDTEAE-LQDATL-ALHGLTVEDEGNYTCEFATFPK 147
            FP P  G+ + +     + ++ TG++     L+D TL  +  +T  D G Y C  A    
Sbjct: 1286 FPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYIC-VAVNEA 1344

Query: 148  GSVRGMTWLRVIAKP--KNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAK 205
            G+      L+V   P  K++ +   V+   +  T   C   EG P   I W        +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFC-EVEGTPSPIIMWYKDNVQVTE 1403

Query: 206  ETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCK-VEHESFEEPALIPVTL-SVRYPPEV 263
             + +     G +    R T   +GR     +       + F    L+P T+    +P EV
Sbjct: 1404 SSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEV 1463

Query: 264  SISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTF---PTSAVAQGSQLVIHAVD 320
            S+        L R D  L C V+  P P  + +      F   P   +    Q V+H  +
Sbjct: 1464 SV-------VLNR-DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQ-VLHLKN 1514

Query: 321  SLFNTT--FVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGI 361
            +  N    + CTV+NA G    +  + +   P+  G   T  I
Sbjct: 1515 ARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDI 1557



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 57/247 (23%), Positives = 96/247 (38%), Gaps = 30/247 (12%)

Query: 123  ATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPK---NQAEAQKVTFSQDPTT 179
            +TL ++G    D G YTC  AT P G    +  L V   P    N+ EA+K+    D T+
Sbjct: 3302 STLNIYGALTSDTGKYTC-VATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVD-TS 3359

Query: 180  VALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCK 239
            + +     G PP +I+WL +       + +    AG V       +V +  +D    TC 
Sbjct: 3360 INIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQV-----IRIVRAQVSDVAVYTCV 3414

Query: 240  VEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDATLSCDVRSNP--------- 289
              + +  +       L V  PP +  S G ++   L  +  +++C     P         
Sbjct: 3415 ASNRAGVDNK--HYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD 3472

Query: 290  -EPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE 348
             +P G D   T  T        G  L +   ++  +  + C  +N  G      ++ V E
Sbjct: 3473 GQPLGLDAHLTVST-------HGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLE 3525

Query: 349  TPNTAGA 355
             P+  G+
Sbjct: 3526 PPHINGS 3532



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 57/244 (23%), Positives = 99/244 (40%), Gaps = 35/244 (14%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
            L ++   + D  NYTC  +     + R    L V   P  +   Q +    + +TV  CI
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFI-LTVNVPPNIKGGPQSLVILLNKSTVLECI 3735

Query: 185  SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSG----RADGVTVT--- 237
            + EG P  RI+W                LAG     +R++++ +G    ++  VT T   
Sbjct: 3736 A-EGVPTPRITWRKD----------GAVLAGN---HARYSILENGFLHIQSAHVTDTGRY 3781

Query: 238  -CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT---- 292
             C   + +  +   I   L V  PP ++  G  +   +     TL+C+    P+P+    
Sbjct: 3782 LCMATNAAGTDRRRID--LQVHVPPSIA-PGPTNMTVIVNVQTTLACEATGIPKPSINWR 3838

Query: 293  --GYDWSTTSGTFPTSAVAQGSQLVIH-AVDSLFNTTFVCTVTNAVGMGRAEQVIFVRET 349
              G+  +          ++ GS ++I  +VD     T+ CTVTN  G  +    + V+  
Sbjct: 3839 KNGHLLNVDQNQNSYRLLSSGSLVIISPSVDD--TATYECTVTNGAGDDKRTVDLTVQVP 3896

Query: 350  PNTA 353
            P+ A
Sbjct: 3897 PSIA 3900



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 85/380 (22%), Positives = 129/380 (33%), Gaps = 68/380 (17%)

Query: 12   SPPTPLLW-------PLLLLLLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLY 64
            +PP  + W       PL   + L    Q +R+     VR Q+       C          
Sbjct: 3369 TPPPQINWLKNGLPLPLSSHIRLLAAGQVIRI-----VRAQVSDVAVYTC---------- 3413

Query: 65   ISLVTWQRPDAPANHQNVAAFHP-----KMGPSFPSPKPGSERLSFVSAKQSTGQDTEAE 119
               V   R      H N+  F P      MG    +   GS   S       T   + A 
Sbjct: 3414 ---VASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSST-SMACITDGTPAPSMAW 3469

Query: 120  LQDA---------TLALHGLTV-------EDEGNYTCEFATFPKGSVRGMTWLRVIAKP- 162
            L+D          T++ HG+ +       ED G YTC  A+   G V     L+V+  P 
Sbjct: 3470 LRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTC-IASNEAGEVSKHFILKVLEPPH 3528

Query: 163  -KNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTS 221
                 E ++++   +      CI+  G P  +++W+       +  QV     G V   S
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIAS-GIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRIS 3587

Query: 222  RFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYD---DNWYLGRTD 278
               +  +GR      TC     + ++     V + V  PP  +I+G D   D   L    
Sbjct: 3588 TAQVEDTGR-----YTCLASSPAGDDDKEYLVRVHV--PP--NIAGTDEPRDITVLRNRQ 3638

Query: 279  ATLSCDVRSNPEPTGYDW----STTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNA 334
             TL C   + P P    W         T     ++ G  L I+  D      + C  +N 
Sbjct: 3639 VTLECKSDAVPPPV-ITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNI 3697

Query: 335  VGMGRAEQVIFVRETPNTAG 354
             G    E ++ V   PN  G
Sbjct: 3698 AGKTTREFILTVNVPPNIKG 3717



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 58/249 (23%), Positives = 93/249 (37%), Gaps = 23/249 (9%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
            LAL    + D G YTC  A    G  +    LRV   P    E Q V+         LC 
Sbjct: 2068 LALTSAQISDTGRYTC-VAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQ 2126

Query: 185  SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHES 244
            S +  PP  ++WL       K+  +S +   +V       +  +GR      TC+  + +
Sbjct: 2127 S-DAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGR-----YTCEATNVA 2180

Query: 245  FEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDA---TLSCDVRSNPEPTGYDWSTTSG 301
             +      V + V  PP  +I G D+   L   +    +L C+    P P    W     
Sbjct: 2181 GKTEKNYNVNIWV--PP--NIGGSDELTQLTVIEGNLISLLCESSGIP-PPNLIWKKKGS 2235

Query: 302  TFPTSAVAQ------GSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQ--VIFVRETPNTA 353
               T ++ +      G QL I   +      + C  +N  G  + E    +++R T   +
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 354  GAGATGGII 362
            G+  T  I+
Sbjct: 2296 GSHPTEIIV 2304



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 59/246 (23%), Positives = 88/246 (35%), Gaps = 24/246 (9%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTW----LRVIAKPK---NQAEAQKVTFSQDP 177
            L L  + V D G Y C        +V GMT     L V A P    N    + ++  +  
Sbjct: 2348 LQLKNIHVSDTGRYVCVAV-----NVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK- 2401

Query: 178  TTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
             +V+L     G P   I+W     W    +     L+G         L+ +   D    T
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKD-GWPVSLSNSVRILSGG----RMLRLMQTTMEDAGQYT 2456

Query: 238  CKVEHESFEEPALIPVTLSVRYPPE-VSISGYDDNWYLGRTDATLSCDVRSNPEPT---G 293
            C V + + EE  +    LSV  PP  V  +  +D     +   TL+C+V  NP P     
Sbjct: 2457 CVVRNAAGEERKIFG--LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWH 2514

Query: 294  YDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTA 353
             D            ++ G  L I  V       + C  ++  G       + V  +P  A
Sbjct: 2515 KDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIA 2574

Query: 354  GAGATG 359
            G G+ G
Sbjct: 2575 GVGSDG 2580



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 50/240 (20%), Positives = 88/240 (36%), Gaps = 16/240 (6%)

Query: 124  TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPK---NQAEAQKVTFSQDPTTV 180
            TL +    V D G YTC  A    G  +    L V   P    + +E+  V   ++ T+V
Sbjct: 3019 TLQIIRAKVSDGGEYTC-IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSV 3077

Query: 181  ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKV 240
            +L       PP  I+W  +     + T V     G +    +  +  +G+       C+ 
Sbjct: 3078 SLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQ-----YVCRA 3132

Query: 241  EHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT-----GYD 295
             + +  +       L+V  PP +     +          TL+CD    P PT      + 
Sbjct: 3133 INVAGRDDKNFH--LNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK 3190

Query: 296  WSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGA 355
                S +     ++ GS+L I       +  + C  +N  G  +    + ++  P+ AGA
Sbjct: 3191 RIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGA 3250



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 79/328 (24%), Positives = 118/328 (35%), Gaps = 41/328 (12%)

Query: 38   VLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPK 97
            V   V G    T  +  H+LP +      L T +    P      A+ +PK  PS    K
Sbjct: 961  VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIE--GIPVTLPCKASGNPK--PSVIWSK 1016

Query: 98   PGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR 157
             G E +S  SAK S G D        +L +     E+ G Y C  AT   G  +    L 
Sbjct: 1017 KG-ELISTSSAKFSAGAD-------GSLYVVSPGGEESGEYVCT-ATNTAGYAKRKVQLT 1067

Query: 158  VIAKPKNQAEAQKVTFSQD-PTTVALCISKEGRPPARISWLSS--LDWEAKETQVSGTLA 214
            V  +P+   + + +  SQD P  +++   +E   P  +  L    + W AKETQ+    +
Sbjct: 1068 VYVRPRVFGDQRGL--SQDKPVEISVLAGEEVTLPCEVKSLPPPIITW-AKETQLISPFS 1124

Query: 215  GTVTVTSRFTLVPSGR--------ADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS 266
                   R T +PSG         +D     C   + +        V L+V  PP++   
Sbjct: 1125 ------PRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQA--VKLNVHVPPKIQRG 1176

Query: 267  GYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQ----LVIHAVDSL 322
                   +G+    + C+ +  P P    WS    T         S     L I      
Sbjct: 1177 PKHLKVQVGQR-VDIPCNAQGTPLPV-ITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234

Query: 323  FNTTFVCTVTNAVGMGRAEQVIFVRETP 350
                + C  TN  G    E  + V+E P
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQEPP 1262



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 78/346 (22%), Positives = 120/346 (34%), Gaps = 70/346 (20%)

Query: 25   LLLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAA 84
            + L+ G+  V +Q   +V  ++G  V LPC+    V G     + W+R D      N+  
Sbjct: 785  ITLDVGSPPVFIQEPADVSMEIGSNVTLPCY----VQGYPEPTIKWRRLD------NMPI 834

Query: 85   FHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFAT 144
            F              S   S  S  Q         L+   L +  L   D+G Y CE A 
Sbjct: 835  F--------------SRPFSVSSISQ---------LRTGALFILNLWASDKGTYICE-AE 870

Query: 145  FPKGSVRGMTWLRVIA----------KPKNQAEAQKVTFSQDPTTVALCISKEGRPPARI 194
               G ++  T + V               N  E Q++T          C    G P    
Sbjct: 871  NQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLP--------CTLLAGNPIPER 922

Query: 195  SWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVT 254
             W+ +     +   ++    G++ +  R  L      DG   TC   + +        V 
Sbjct: 923  RWIKNSAMLLQNPYITVRSDGSLHI-ERVQL-----QDGGEYTCVASNVAGTNNKTTSVV 976

Query: 255  LSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPT------GYDWSTTSGTFPTSAV 308
            + V   P +   G      +     TL C    NP+P+      G   ST+S  F  SA 
Sbjct: 977  VHVL--PTIQ-HGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF--SAG 1031

Query: 309  AQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG 354
            A GS  V+ +     +  +VCT TN  G  + +  + V   P   G
Sbjct: 1032 ADGSLYVV-SPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFG 1076



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 52/214 (24%), Positives = 76/214 (35%), Gaps = 18/214 (8%)

Query: 132  VEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPP 191
            V D G Y C  A    G       L V   P  +   ++V        V L     G PP
Sbjct: 3122 VSDTGQYVCR-AINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPP 3180

Query: 192  ARISWLSSLDWEAKETQVSGTL-AGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPAL 250
              I+WL +     K  + S +L    ++  S+  +  S  +D    TC     + E  A 
Sbjct: 3181 PTIAWLKN----HKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIA--SNMEGKAQ 3234

Query: 251  IPVTLSVRYPPEVSISGY--DDNWYLGRTDATLSCDVRSNPEPTGYDW------STTSGT 302
                LS++ PP V+ +    D +  LG  +  L C+    P P    W        +  T
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGE-NVELVCNANGIPTPL-IQWLKDGKPIASGET 3292

Query: 303  FPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
                  A GS L I+   +     + C  TN  G
Sbjct: 3293 ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 57/271 (21%), Positives = 99/271 (36%), Gaps = 28/271 (10%)

Query: 123  ATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPK--NQAEAQKVTFSQDPTTV 180
            + L +    V+D G YTCE AT   G       + +   P      E  ++T  +     
Sbjct: 2157 SVLKIEDAQVQDTGRYTCE-ATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLIS 2215

Query: 181  ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTS---RFTLVPSGRADGVTVT 237
             LC S    PP       +L W+ K + V     G V + S   +  +  + ++D    +
Sbjct: 2216 LLCESSGIPPP-------NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYS 2268

Query: 238  CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYL---GRTDATLSCDVRSNPEPT-- 292
            C   + +    A     L V   P ++ SG      +   G++  +L C+V+  P PT  
Sbjct: 2269 CVASNVA--GTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTVT 2325

Query: 293  ----GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE 348
                G+      G      + +G  L +  +       +VC   N  GM   +  + V  
Sbjct: 2326 WMKDGHPLIKAKG---VEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382

Query: 349  TPNTAGAGATGGIIGGIIAAIIATAVAATGI 379
             P+  G   +   I  +    ++    A+GI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGI 2413



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 25/234 (10%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
            L L  + +ED G YTC  A    G       L V   P         TF++ P  V+L  
Sbjct: 4224 LILENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLP---------TFTELPGDVSLNK 4273

Query: 185  SKEGRPPARISW--LSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH 242
             ++ R   + +   L  L W      +      +V   S   +    + D  T  C  E+
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAEN 4332

Query: 243  ESFEEPALIPVTLSVRYPPEVSISGYDDNWY--LGRTDATLSCDVRSNPEPTGYDWSTTS 300
                  A+  V   V+ PP V    Y  NW   LG  +A L+C+V+ +P PT   W+   
Sbjct: 4333 SVGFVKAIGFVY--VKEPP-VFKGDYPSNWIEPLGG-NAILNCEVKGDPTPT-IQWNRKG 4387

Query: 301  GTFPTS----AVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
                 S     +  GS L I+   +     + C  TN  G+      + ++  P
Sbjct: 4388 VDIEISHRIRQLGNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 51/231 (22%), Positives = 83/231 (35%), Gaps = 31/231 (13%)

Query: 122  DATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA 181
            D +L +  + ++D G YTC  A+   G+    T + V   P  Q   Q++  + +   V 
Sbjct: 942  DGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQ-HGQQILSTIEGIPVT 999

Query: 182  LCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVE 241
            L     G P   + W  S   E   T  +   AG     S + + P G   G  V C   
Sbjct: 1000 LPCKASGNPKPSVIW--SKKGELISTSSAKFSAG--ADGSLYVVSPGGEESGEYV-CTAT 1054

Query: 242  HESFEEPALIPVTLSVR-------------YPPEVSISGYDDNWYLGRTDATLSCDVRSN 288
            + +      + +T+ VR              P E+S+        L   + TL C+V+S 
Sbjct: 1055 NTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV--------LAGEEVTLPCEVKSL 1106

Query: 289  PEPT---GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
            P P      +    S   P         + I    +  +  ++C  TN  G
Sbjct: 1107 PPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAG 1157



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 37/174 (21%), Positives = 58/174 (33%), Gaps = 13/174 (7%)

Query: 188  GRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEE 247
            G PP  I WL       +       L G   V ++  +  +G    +      +H+   E
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819

Query: 248  PALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTS---GTFP 304
                   ++V  PP +  SG  +   +      L C     P P+   W        T  
Sbjct: 1820 -------VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPS-ITWLKDDQPVNTAQ 1871

Query: 305  TSAVAQGSQLVIHAVDSLFNTT--FVCTVTNAVGMGRAEQVIFVRETPNTAGAG 356
             +   Q S  V+    +L      + C  TNA G  +    + V E P+   AG
Sbjct: 1872 GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAG 1925



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 5/95 (5%)

Query: 119  ELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPT 178
            +L + +LA++G   ED G+YTC  AT   G V     L + + P    E  +   +    
Sbjct: 4398 QLGNGSLAIYGTVNEDAGDYTC-VATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGK 4456

Query: 179  TVALCISKEGRPPARISWL---SSLDWEAKETQVS 210
             +  C    G P   I+W     S+ W+ +   +S
Sbjct: 4457 IILNC-QATGEPQPTITWSRQGHSISWDDRVNVLS 4490



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 72/301 (23%), Positives = 106/301 (35%), Gaps = 35/301 (11%)

Query: 2    ARAAALLPSRSPPTPLLWPLLLLLLLETGAQD--VRVQVLPEVRGQLGGTVELPCHLLPP 59
            A+   L+   SP    L P   + + ET   D  + + V   + G +   V+L  H+ P 
Sbjct: 1114 AKETQLISPFSPRHTFL-PSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPK 1172

Query: 60   VPG--LYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTE 117
            +     ++ +   QR D P N Q          P     K GS  L           +  
Sbjct: 1173 IQRGPKHLKVQVGQRVDIPCNAQGTPL------PVITWSKGGSTML--------VDGEHH 1218

Query: 118  AELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKP--KNQAEAQKVTFSQ 175
                D TL++   T  D G YTC  AT   G+      L V   P  ++       TF +
Sbjct: 1219 VSNPDGTLSIDQATPSDAGIYTC-VATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQE 1277

Query: 176  DPTTVAL---CISKEGRPPARISWL-SSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRA 231
                  +   C +K G P   I WL +  +   +E  +S    GT+ V +  T   +G  
Sbjct: 1278 RVANQRIEFPCPAK-GTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEY 1336

Query: 232  DGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDAT-LSCDVRSNPE 290
              V V    E  + E        L V  PP +       N  +     T L C+V   P 
Sbjct: 1337 ICVAVN---EAGTTER----KYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPS 1389

Query: 291  P 291
            P
Sbjct: 1390 P 1390



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 53/230 (23%), Positives = 81/230 (35%), Gaps = 27/230 (11%)

Query: 120  LQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTT 179
            L   ++ +      D G Y C  AT   G+V     L V   PK Q   + +   Q    
Sbjct: 1130 LPSGSMKITETRTSDSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGPKHLKV-QVGQR 1187

Query: 180  VALCISKEGRPPARISWLSS-----LDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV 234
            V +  + +G P   I+W        +D E   +   GTL+      S          D  
Sbjct: 1188 VDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS----------DAG 1237

Query: 235  TVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDAT----LSCDVRSNPE 290
              TC   + +  +     +TL V+ PP V       N       A       C  +  P+
Sbjct: 1238 IYTCVATNIAGTDET--EITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPK 1295

Query: 291  PTG---YDWSTTSGTFP-TSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
            PT    ++    +G  P  S +  G+ LVI +V    N  ++C   N  G
Sbjct: 1296 PTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345


>gi|157739930 TAP binding protein-like [Homo sapiens]
          Length = 468

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 45/139 (32%), Positives = 68/139 (48%), Gaps = 21/139 (15%)

Query: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQA----EAQKVTFSQD 176
           +DA+L L GLT++DEG Y C+  T      + +  L + A PK +     EA   T   D
Sbjct: 264 RDASLTLPGLTIQDEGTYICQITT-SLYRAQQIIQLNIQASPKVRLSLANEALLPTLICD 322

Query: 177 -----PTTVALCISKE--GRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSG 229
                P  V +  ++E  G  PA++S        A  + +  ++AGT +++S  T  P  
Sbjct: 323 IAGYYPLDVVVTWTREELGGSPAQVS-------GASFSSLRQSVAGTYSISSSLTAEPG- 374

Query: 230 RADGVTVTCKVEHESFEEP 248
            + G T TC+V H S EEP
Sbjct: 375 -SAGATYTCQVTHISLEEP 392


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 64/255 (25%), Positives = 96/255 (37%), Gaps = 22/255 (8%)

Query: 110  QSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKP--KNQAE 167
            Q  G      L   +L L GL   D G YTC  A  P G    +  + V+  P  K  A+
Sbjct: 2069 QDMGPHLRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGAD 2127

Query: 168  AQKVTFSQDPTTVALCISKEGRPPARISWL-SSLDWE-AKETQVSGTLAGTVTVTSRFTL 225
                  S+    V +     G PP  +SWL   L    ++ T + G  +G     S+  L
Sbjct: 2128 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHG--SGHTLRISKVQL 2185

Query: 226  VPSGRADGVTVTCKVEHESFEEPALIP---VTLSVRYPPEVSISGYDDNWYLGRTD-ATL 281
                 AD    TC         PA +     TL V+ PP +    + ++  + R     L
Sbjct: 2186 -----ADAGIFTCVA-----ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2235

Query: 282  SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
             C+ R  P P    W        + ++ QG  L + AV +  + T+ C   +  G  R  
Sbjct: 2236 PCEARGVPLPL-VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 2294

Query: 342  QVIFVRETPNTAGAG 356
              + V E P+   +G
Sbjct: 2295 FQLTVMEPPHIEDSG 2309



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 66/253 (26%), Positives = 97/253 (38%), Gaps = 28/253 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK 170
            +TG  T+  L    L +   + ED GNY C  A    GS  G T L V   P  +     
Sbjct: 2798 ATGVSTQV-LPGGQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPD 2855

Query: 171  VTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR 230
            ++ ++       C ++    P       ++ W+     VSG          +FT+ PSG 
Sbjct: 2856 LSTTEGSHAFLPCKARGSPEP-------NITWDKDGQPVSGA-------EGKFTIQPSGE 2901

Query: 231  A--------DGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
                     D  T TC  E+        + +T+ V  P   ++ G D +  LG     L 
Sbjct: 2902 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV-LPVFTTLPG-DRSLRLGDR-LWLR 2958

Query: 283  CDVRSNPEPT-GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
            C  R +P P  G+  +    T   S    GS L   AV    + T+VC   N VG  +A 
Sbjct: 2959 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 3018

Query: 342  QVIFVRETPNTAG 354
              + V+E P   G
Sbjct: 3019 SFVHVKEAPVLQG 3031



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 52/237 (21%), Positives = 90/237 (37%), Gaps = 18/237 (7%)

Query: 125 LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
           L +  + + DEG YTC  AT   G  +    L+V+  P  +         ++ +    C+
Sbjct: 659 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECL 717

Query: 185 SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR-ADGVTVTCKVEHE 243
           +  G PP  +SW            VS  +  TV+V  R   +   + +D  +  C   + 
Sbjct: 718 AS-GVPPPDVSWFKG------HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 770

Query: 244 SFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW------S 297
           +      +   L V  PP +++        L  T   L+C+    P PT   W       
Sbjct: 771 AGSTE--LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPT-LMWLKDGNPV 827

Query: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG 354
           + +GT        G  L + +  +  +  + C   +AVG  R + V+ V   P+  G
Sbjct: 828 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 884



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 56/243 (23%), Positives = 90/243 (37%), Gaps = 22/243 (9%)

Query: 124  TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV--- 180
            TL L    + D G YTCE A    G  + +  L V+  P   A  Q     QD   V   
Sbjct: 1801 TLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP---AFRQAPRGPQDAVLVRVG 1856

Query: 181  ---ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
                L    +  P   ++W     ++  +  V       +    R  +  +  +D    +
Sbjct: 1857 DKAVLSCETDALPEPTVTW-----YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 1911

Query: 238  CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            CKV + + E  A+   TL+V+ PP       +    +  +   L+CDV   P PT   W 
Sbjct: 1912 CKVSNVAGE--AVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT-VTWL 1968

Query: 298  TTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTA 353
                   +SA    V++G +L +  +      T+ C   N     R + V+ V   P   
Sbjct: 1969 KDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIR 2028

Query: 354  GAG 356
             +G
Sbjct: 2029 SSG 2031



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 41/179 (22%), Positives = 65/179 (36%), Gaps = 9/179 (5%)

Query: 114  QDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTF 173
            Q T+A      L +    V D+G Y+C+ +     +VR  T L V   P  +    +   
Sbjct: 1886 QRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFT-LTVQVPPTFENPKTETVS 1944

Query: 174  SQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADG 233
                + + L     G P   ++WL       +    S  + G V+   R  L     A  
Sbjct: 1945 QVAGSPLVLTCDVSGVPAPTVTWLKD-----RMPVESSAVHGVVSRGGRLQLSRLQPAQA 1999

Query: 234  VTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGY-DDNWYLGRTDATLSCDVRSNPEP 291
             T TC  E+   E  A     ++V   P +  SG   ++  L   +  L C+    P P
Sbjct: 2000 GTYTCVAENTQAE--ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP 2056



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 42/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR----VIAKP---- 162
            S G +         L +  +  E+ G Y+C+ +     +  G  WL     V+  P    
Sbjct: 1601 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS-----NEVGEDWLHYELLVLTPPVILG 1655

Query: 163  KNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSR 222
              +   ++VT +   +TV+L     G P   ISWL +    +   ++     G V   S 
Sbjct: 1656 DTEELVEEVTVNAS-STVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVST 1714

Query: 223  FTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
              +     AD  +  C  E+++     L   TL V+ PP ++    +    +  +  +L 
Sbjct: 1715 AEV-----ADAASYMCVAENQAGSAEKLF--TLRVQVPPRIAGLDLEQVTAILNSSVSLP 1767

Query: 283  CDVRSNPEP 291
            CDV ++P P
Sbjct: 1768 CDVHAHPNP 1776



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 113  GQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVT 172
            G     +LQ+ +L +H    +D G Y C  A    G  + +  L + + P  Q E Q +T
Sbjct: 3070 GSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDMT 3128

Query: 173  FSQDPTTVALCISKEGRPPARISWLSS 199
              +    VAL     G P   I WL +
Sbjct: 3129 V-RSGDDVALRCQATGEPTPTIEWLQA 3154



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/102 (25%), Positives = 35/102 (34%), Gaps = 5/102 (4%)

Query: 281 LSCDVRSNPEPTGYDWSTTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
           L C+ R  P P    W       PTS        G QL +    S     + C  +NAVG
Sbjct: 331 LLCEARGVPTPN-ITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 389

Query: 337 MGRAEQVIFVRETPNTAGAGATGGIIGGIIAAIIATAVAATG 378
                  + V   P   GAG    ++  +    +A    A G
Sbjct: 390 AAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARG 431



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 9/122 (7%)

Query: 95  SPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMT 154
           +PKP        S++   GQ   A L++ +L L  ++  D G+Y C+ AT   GS     
Sbjct: 29  TPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQ-ATNEVGSTSRRA 87

Query: 155 WLRVIAKPKNQAEAQKVTFS-QDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTL 213
            L V   P  + + +K   S     ++ L     G P   I WL       K+ Q+ G  
Sbjct: 88  KLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWL-------KDAQLVGVP 140

Query: 214 AG 215
            G
Sbjct: 141 LG 142



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 52/220 (23%), Positives = 80/220 (36%), Gaps = 16/220 (7%)

Query: 134 DEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK--VTFSQDPTTVALCISKEGRPP 191
           D G YTC+ A+   G+    T L V   P  +    +  V  +     VAL     G P 
Sbjct: 376 DAGVYTCK-ASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPS 434

Query: 192 ARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALI 251
             +SW       A+  +      G+V       L   G A     +C     + E  A++
Sbjct: 435 PTLSWHHEGLPVAESNESRLETDGSV-----LRLESPGEASSGLYSCVASSPAGE--AVL 487

Query: 252 PVTLSVRYPPEVSIS-GYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSA--- 307
             ++ V+ PP++ ++ G      +      L C    +P PT   W          A   
Sbjct: 488 QYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQ 546

Query: 308 -VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFV 346
             +QG+ L I  V+   +  F C  TN  G   AE  + V
Sbjct: 547 VASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 586


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 64/255 (25%), Positives = 96/255 (37%), Gaps = 22/255 (8%)

Query: 110  QSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKP--KNQAE 167
            Q  G      L   +L L GL   D G YTC  A  P G    +  + V+  P  K  A+
Sbjct: 3260 QDMGPHLRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGAD 3318

Query: 168  AQKVTFSQDPTTVALCISKEGRPPARISWL-SSLDWE-AKETQVSGTLAGTVTVTSRFTL 225
                  S+    V +     G PP  +SWL   L    ++ T + G  +G     S+  L
Sbjct: 3319 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHG--SGHTLRISKVQL 3376

Query: 226  VPSGRADGVTVTCKVEHESFEEPALIP---VTLSVRYPPEVSISGYDDNWYLGRTD-ATL 281
                 AD    TC         PA +     TL V+ PP +    + ++  + R     L
Sbjct: 3377 -----ADAGIFTCVA-----ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 3426

Query: 282  SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
             C+ R  P P    W        + ++ QG  L + AV +  + T+ C   +  G  R  
Sbjct: 3427 PCEARGVPLPL-VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 3485

Query: 342  QVIFVRETPNTAGAG 356
              + V E P+   +G
Sbjct: 3486 FQLTVMEPPHIEDSG 3500



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 65/285 (22%), Positives = 107/285 (37%), Gaps = 32/285 (11%)

Query: 93  FPSPKPGSERLSFVSAKQSTGQDTEAELQ-DATLALHGLTVEDEGNYTCEFATFPKGSVR 151
           +P+P      +S+    Q+  +D+   +    TL + G+  ED GNY+C+ AT   G+ +
Sbjct: 634 YPTP-----HISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQ-ATNEVGTDQ 687

Query: 152 GMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSG 211
               L     P   A    V  +     V +C    G PP R+ W            +  
Sbjct: 688 ETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVC-EASGVPPPRVIWYRG--------GLEM 738

Query: 212 TLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDN 271
            LA   + + +  +  +   D  T TC+  +E  +  A   + L+V + P+++    D  
Sbjct: 739 ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASA--EIQLAVGHAPQLTELPRDVT 796

Query: 272 WYLGRTDATLSCDVRSNPEPTGYDW----------STTSGTFPTSAVAQGSQLVIHAVDS 321
             LGR+ A L+C     P PT   W             +G    S       L   +V  
Sbjct: 797 VELGRS-ALLACRATGRPPPT-VTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAP 854

Query: 322 LFNTTFVCTVTNAVGMGRAEQVIFV--RETPNTAGAGATGGIIGG 364
                +VC   N  G  +AE  + V     P  A +  T  ++ G
Sbjct: 855 EDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEG 899



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 64/255 (25%), Positives = 95/255 (37%), Gaps = 31/255 (12%)

Query: 134 DEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPAR 193
           +EG Y C  A    G+ R    + V   P     A  VT S   T V  C    G  P  
Sbjct: 490 EEGTYECT-AVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSC-RVLGEAPYN 547

Query: 194 ISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSG--RADGVTVTCKVEHESFEEPALI 251
           ++W+   DW     +V     G V   +  +L  SG    DG    C   + +    A  
Sbjct: 548 LTWVR--DW-----RVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-- 598

Query: 252 PVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAV--- 308
            V L VR  P+VSI     ++  G  +  +SC     P P    WS  S      +    
Sbjct: 599 SVWLLVREAPQVSIHTSSQHFSQG-VEVKVSCSASGYPTPH-ISWSRESQALQEDSRIHV 656

Query: 309 -AQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATGGIIGGIIA 367
            AQG+ L+I  V       + C  TN VG  +    ++  + P+ +            + 
Sbjct: 657 DAQGT-LIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSA-----------VN 704

Query: 368 AIIATAVAATGILIC 382
           A++  AV    +L+C
Sbjct: 705 AVVLVAVGEEAVLVC 719



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 66/253 (26%), Positives = 97/253 (38%), Gaps = 28/253 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK 170
            +TG  T+  L    L +   + ED GNY C  A    GS  G T L V   P  +     
Sbjct: 3989 ATGVSTQV-LPGGQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPD 4046

Query: 171  VTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR 230
            ++ ++       C ++    P       ++ W+     VSG          +FT+ PSG 
Sbjct: 4047 LSTTEGSHAFLPCKARGSPEP-------NITWDKDGQPVSGA-------EGKFTIQPSGE 4092

Query: 231  A--------DGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
                     D  T TC  E+        + +T+ V  P   ++ G D +  LG     L 
Sbjct: 4093 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV-LPVFTTLPG-DRSLRLGDR-LWLR 4149

Query: 283  CDVRSNPEPT-GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
            C  R +P P  G+  +    T   S    GS L   AV    + T+VC   N VG  +A 
Sbjct: 4150 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 4209

Query: 342  QVIFVRETPNTAG 354
              + V+E P   G
Sbjct: 4210 SFVHVKEAPVLQG 4222



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 52/237 (21%), Positives = 90/237 (37%), Gaps = 18/237 (7%)

Query: 125  LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
            L +  + + DEG YTC  AT   G  +    L+V+  P  +         ++ +    C+
Sbjct: 1850 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECL 1908

Query: 185  SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR-ADGVTVTCKVEHE 243
            +  G PP  +SW            VS  +  TV+V  R   +   + +D  +  C   + 
Sbjct: 1909 AS-GVPPPDVSWFKG------HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 1961

Query: 244  SFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW------S 297
            +      +   L V  PP +++        L  T   L+C+    P PT   W       
Sbjct: 1962 AGSTE--LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPT-LMWLKDGNPV 2018

Query: 298  TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG 354
            + +GT        G  L + +  +  +  + C   +AVG  R + V+ V   P+  G
Sbjct: 2019 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 2075



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 56/243 (23%), Positives = 90/243 (37%), Gaps = 22/243 (9%)

Query: 124  TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV--- 180
            TL L    + D G YTCE A    G  + +  L V+  P   A  Q     QD   V   
Sbjct: 2992 TLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP---AFRQAPRGPQDAVLVRVG 3047

Query: 181  ---ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
                L    +  P   ++W     ++  +  V       +    R  +  +  +D    +
Sbjct: 3048 DKAVLSCETDALPEPTVTW-----YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 3102

Query: 238  CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            CKV + + E  A+   TL+V+ PP       +    +  +   L+CDV   P PT   W 
Sbjct: 3103 CKVSNVAGE--AVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT-VTWL 3159

Query: 298  TTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTA 353
                   +SA    V++G +L +  +      T+ C   N     R + V+ V   P   
Sbjct: 3160 KDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIR 3219

Query: 354  GAG 356
             +G
Sbjct: 3220 SSG 3222



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 52/215 (24%), Positives = 79/215 (36%), Gaps = 19/215 (8%)

Query: 91   PSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSV 150
            P+  +PKP        S++   GQ   A L++ +L L  ++  D G+Y C+ AT   GS 
Sbjct: 1229 PARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQ-ATNEVGST 1287

Query: 151  RGMTWLRVIAKPKNQAEAQKVTFS-QDPTTVALCISKEGRPPARISWL------------ 197
                 L V   P  + + +K   S     ++ L     G P   I WL            
Sbjct: 1288 SRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGW 1347

Query: 198  SSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSV 257
            +   W+    QV G        +  F  +  G  D    +C+ E+++    A     L V
Sbjct: 1348 AGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEG--DSGLYSCRAENQA--GTAQRDFHLLV 1403

Query: 258  RYPPEVSISG-YDDNWYLGRTDATLSCDVRSNPEP 291
              PP V  +G   +   L   D  L C     P P
Sbjct: 1404 LTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTP 1438



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 41/179 (22%), Positives = 65/179 (36%), Gaps = 9/179 (5%)

Query: 114  QDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTF 173
            Q T+A      L +    V D+G Y+C+ +     +VR  T L V   P  +    +   
Sbjct: 3077 QRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFT-LTVQVPPTFENPKTETVS 3135

Query: 174  SQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADG 233
                + + L     G P   ++WL       +    S  + G V+   R  L     A  
Sbjct: 3136 QVAGSPLVLTCDVSGVPAPTVTWLKD-----RMPVESSAVHGVVSRGGRLQLSRLQPAQA 3190

Query: 234  VTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGY-DDNWYLGRTDATLSCDVRSNPEP 291
             T TC  E+   E  A     ++V   P +  SG   ++  L   +  L C+    P P
Sbjct: 3191 GTYTCVAENTQAE--ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP 3247



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 42/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR----VIAKP---- 162
            S G +         L +  +  E+ G Y+C+ +     +  G  WL     V+  P    
Sbjct: 2792 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS-----NEVGEDWLHYELLVLTPPVILG 2846

Query: 163  KNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSR 222
              +   ++VT +   +TV+L     G P   ISWL +    +   ++     G V   S 
Sbjct: 2847 DTEELVEEVTVNAS-STVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVST 2905

Query: 223  FTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
              +     AD  +  C  E+++     L   TL V+ PP ++    +    +  +  +L 
Sbjct: 2906 AEV-----ADAASYMCVAENQAGSAEKLF--TLRVQVPPRIAGLDLEQVTAILNSSVSLP 2958

Query: 283  CDVRSNPEP 291
            CDV ++P P
Sbjct: 2959 CDVHAHPNP 2967



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 113  GQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVT 172
            G     +LQ+ +L +H    +D G Y C  A    G  + +  L + + P  Q E Q +T
Sbjct: 4261 GSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDMT 4319

Query: 173  FSQDPTTVALCISKEGRPPARISWLSS 199
              +    VAL     G P   I WL +
Sbjct: 4320 V-RSGDDVALRCQATGEPTPTIEWLQA 4345



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/102 (25%), Positives = 35/102 (34%), Gaps = 5/102 (4%)

Query: 281  LSCDVRSNPEPTGYDWSTTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
            L C+ R  P P    W       PTS        G QL +    S     + C  +NAVG
Sbjct: 1522 LLCEARGVPTPN-ITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 1580

Query: 337  MGRAEQVIFVRETPNTAGAGATGGIIGGIIAAIIATAVAATG 378
                   + V   P   GAG    ++  +    +A    A G
Sbjct: 1581 AAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARG 1622



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 52/220 (23%), Positives = 80/220 (36%), Gaps = 16/220 (7%)

Query: 134  DEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK--VTFSQDPTTVALCISKEGRPP 191
            D G YTC+ A+   G+    T L V   P  +    +  V  +     VAL     G P 
Sbjct: 1567 DAGVYTCK-ASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPS 1625

Query: 192  ARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALI 251
              +SW       A+  +      G+V       L   G A     +C     + E  A++
Sbjct: 1626 PTLSWHHEGLPVAESNESRLETDGSV-----LRLESPGEASSGLYSCVASSPAGE--AVL 1678

Query: 252  PVTLSVRYPPEVSIS-GYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSA--- 307
              ++ V+ PP++ ++ G      +      L C    +P PT   W          A   
Sbjct: 1679 QYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQ 1737

Query: 308  -VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFV 346
              +QG+ L I  V+   +  F C  TN  G   AE  + V
Sbjct: 1738 VASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 54/228 (23%), Positives = 79/228 (34%), Gaps = 17/228 (7%)

Query: 125  LALHGLTVEDEGNYTCEFAT-FPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALC 183
            L    +  ED+  Y CE    F K        +   A P+  + A  V   +       C
Sbjct: 847  LFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPC 906

Query: 184  ISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGV-TVTCKVEH 242
            I   GRP     WL         ++ S    G++ +  R     +GR   V T T   +H
Sbjct: 907  IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHL-DRALQEHAGRYSCVATNTAGSQH 965

Query: 243  ESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGT 302
               E        L V+ PP +  +        G   A+L C     P PT   W+  +  
Sbjct: 966  RDVE--------LVVQVPPRIHPTATHHITNEG-VPASLPCVASGVPAPT-ITWTKETNA 1015

Query: 303  F----PTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFV 346
                 P   V++   L+I    +     +VCT TN VG    E  + V
Sbjct: 1016 LTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSV 1063



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 51/254 (20%), Positives = 78/254 (30%), Gaps = 27/254 (10%)

Query: 130  LTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDP-TTVALCISKEG 188
            +   D G Y CE A+   G       LRV+  P   A+       +      +L     G
Sbjct: 1174 IRTSDAGRYRCE-ASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARG 1232

Query: 189  RPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEP 248
             P  +++W      E     + G     V       L     AD     C+  +E     
Sbjct: 1233 TPKPQVTWRKGPSSEP----LHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTS 1288

Query: 249  ALIPVTLSVRYPPEVSISGYDDNWY-LGRTDATLSCDVRSNPEP---------------- 291
                + + V  PP +   G   N   +     TL CD    P P                
Sbjct: 1289 RRAKLVVYV--PPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLG 1346

Query: 292  -TGYDWSTTSGTFPTSAVA-QGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRET 349
              GY W    G      +  +G  L    +    +  + C   N  G  + +  + V   
Sbjct: 1347 WAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTP 1406

Query: 350  PNTAGAGATGGIIG 363
            P+  GAGA   ++G
Sbjct: 1407 PSVLGAGAAQEVLG 1420


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 64/255 (25%), Positives = 96/255 (37%), Gaps = 22/255 (8%)

Query: 110  QSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKP--KNQAE 167
            Q  G      L   +L L GL   D G YTC  A  P G    +  + V+  P  K  A+
Sbjct: 1978 QDMGPHLRFYLDGGSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGAD 2036

Query: 168  AQKVTFSQDPTTVALCISKEGRPPARISWL-SSLDWE-AKETQVSGTLAGTVTVTSRFTL 225
                  S+    V +     G PP  +SWL   L    ++ T + G  +G     S+  L
Sbjct: 2037 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHG--SGHTLRISKVQL 2094

Query: 226  VPSGRADGVTVTCKVEHESFEEPALIP---VTLSVRYPPEVSISGYDDNWYLGRTD-ATL 281
                 AD    TC         PA +     TL V+ PP +    + ++  + R     L
Sbjct: 2095 -----ADAGIFTCVA-----ASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2144

Query: 282  SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
             C+ R  P P    W        + ++ QG  L + AV +  + T+ C   +  G  R  
Sbjct: 2145 PCEARGVPLPL-VSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRH 2203

Query: 342  QVIFVRETPNTAGAG 356
              + V E P+   +G
Sbjct: 2204 FQLTVMEPPHIEDSG 2218



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 66/253 (26%), Positives = 97/253 (38%), Gaps = 28/253 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK 170
            +TG  T+  L    L +   + ED GNY C  A    GS  G T L V   P  +     
Sbjct: 2707 ATGVSTQV-LPGGQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPD 2764

Query: 171  VTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR 230
            ++ ++       C ++    P       ++ W+     VSG          +FT+ PSG 
Sbjct: 2765 LSTTEGSHAFLPCKARGSPEP-------NITWDKDGQPVSGA-------EGKFTIQPSGE 2810

Query: 231  A--------DGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
                     D  T TC  E+        + +T+ V  P   ++ G D +  LG     L 
Sbjct: 2811 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILV-LPVFTTLPG-DRSLRLGDR-LWLR 2867

Query: 283  CDVRSNPEPT-GYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
            C  R +P P  G+  +    T   S    GS L   AV    + T+VC   N VG  +A 
Sbjct: 2868 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAV 2927

Query: 342  QVIFVRETPNTAG 354
              + V+E P   G
Sbjct: 2928 SFVHVKEAPVLQG 2940



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 52/237 (21%), Positives = 90/237 (37%), Gaps = 18/237 (7%)

Query: 125 LALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCI 184
           L +  + + DEG YTC  AT   G  +    L+V+  P  +         ++ +    C+
Sbjct: 568 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECL 626

Query: 185 SKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGR-ADGVTVTCKVEHE 243
           +  G PP  +SW            VS  +  TV+V  R   +   + +D  +  C   + 
Sbjct: 627 AS-GVPPPDVSWFKG------HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 679

Query: 244 SFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW------S 297
           +      +   L V  PP +++        L  T   L+C+    P PT   W       
Sbjct: 680 AGSTE--LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPT-LMWLKDGNPV 736

Query: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAG 354
           + +GT        G  L + +  +  +  + C   +AVG  R + V+ V   P+  G
Sbjct: 737 SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 793



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 56/243 (23%), Positives = 90/243 (37%), Gaps = 22/243 (9%)

Query: 124  TLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTV--- 180
            TL L    + D G YTCE A    G  + +  L V+  P   A  Q     QD   V   
Sbjct: 1710 TLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP---AFRQAPRGPQDAVLVRVG 1765

Query: 181  ---ALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
                L    +  P   ++W     ++  +  V       +    R  +  +  +D    +
Sbjct: 1766 DKAVLSCETDALPEPTVTW-----YKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 1820

Query: 238  CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
            CKV + + E  A+   TL+V+ PP       +    +  +   L+CDV   P PT   W 
Sbjct: 1821 CKVSNVAGE--AVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT-VTWL 1877

Query: 298  TTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTA 353
                   +SA    V++G +L +  +      T+ C   N     R + V+ V   P   
Sbjct: 1878 KDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIR 1937

Query: 354  GAG 356
             +G
Sbjct: 1938 SSG 1940



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 41/179 (22%), Positives = 65/179 (36%), Gaps = 9/179 (5%)

Query: 114  QDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTF 173
            Q T+A      L +    V D+G Y+C+ +     +VR  T L V   P  +    +   
Sbjct: 1795 QRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFT-LTVQVPPTFENPKTETVS 1853

Query: 174  SQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADG 233
                + + L     G P   ++WL       +    S  + G V+   R  L     A  
Sbjct: 1854 QVAGSPLVLTCDVSGVPAPTVTWLKD-----RMPVESSAVHGVVSRGGRLQLSRLQPAQA 1908

Query: 234  VTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGY-DDNWYLGRTDATLSCDVRSNPEP 291
             T TC  E+   E  A     ++V   P +  SG   ++  L   +  L C+    P P
Sbjct: 1909 GTYTCVAENTQAE--ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPP 1965



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 42/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)

Query: 111  STGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLR----VIAKP---- 162
            S G +         L +  +  E+ G Y+C+ +     +  G  WL     V+  P    
Sbjct: 1510 SAGDEVSVLQGGRVLQIPLVRAENAGRYSCKAS-----NEVGEDWLHYELLVLTPPVILG 1564

Query: 163  KNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSR 222
              +   ++VT +   +TV+L     G P   ISWL +    +   ++     G V   S 
Sbjct: 1565 DTEELVEEVTVNAS-STVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVST 1623

Query: 223  FTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLS 282
              +     AD  +  C  E+++     L   TL V+ PP ++    +    +  +  +L 
Sbjct: 1624 AEV-----ADAASYMCVAENQAGSAEKLF--TLRVQVPPRIAGLDLEQVTAILNSSVSLP 1676

Query: 283  CDVRSNPEP 291
            CDV ++P P
Sbjct: 1677 CDVHAHPNP 1685



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/102 (25%), Positives = 35/102 (34%), Gaps = 5/102 (4%)

Query: 281 LSCDVRSNPEPTGYDWSTTSGTFPTSA----VAQGSQLVIHAVDSLFNTTFVCTVTNAVG 336
           L C+ R  P P    W       PTS        G QL +    S     + C  +NAVG
Sbjct: 240 LLCEARGVPTPN-ITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 298

Query: 337 MGRAEQVIFVRETPNTAGAGATGGIIGGIIAAIIATAVAATG 378
                  + V   P   GAG    ++  +    +A    A G
Sbjct: 299 AAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARG 340



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 52/220 (23%), Positives = 80/220 (36%), Gaps = 16/220 (7%)

Query: 134 DEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQK--VTFSQDPTTVALCISKEGRPP 191
           D G YTC+ A+   G+    T L V   P  +    +  V  +     VAL     G P 
Sbjct: 285 DAGVYTCK-ASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPS 343

Query: 192 ARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALI 251
             +SW       A+  +      G+V       L   G A     +C     + E  A++
Sbjct: 344 PTLSWHHEGLPVAESNESRLETDGSV-----LRLESPGEASSGLYSCVASSPAGE--AVL 396

Query: 252 PVTLSVRYPPEVSIS-GYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSA--- 307
             ++ V+ PP++ ++ G      +      L C    +P PT   W          A   
Sbjct: 397 QYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQ 455

Query: 308 -VAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFV 346
             +QG+ L I  V+   +  F C  TN  G   AE  + V
Sbjct: 456 VASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 495



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 113  GQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVT 172
            G     +LQ+ +L +     +D G Y C  A    G  + +  L + + P  Q E Q +T
Sbjct: 2979 GSHLRHQLQNGSLTIRRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDMT 3037

Query: 173  FSQDPTTVALCISKEGRPPARISWLSS 199
              +    VAL     G P   I WL +
Sbjct: 3038 V-RSGDDVALRCQATGEPTPTIEWLQA 3063


>gi|45594240 limbic system-associated membrane protein [Homo
           sapiens]
          Length = 338

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 67/272 (24%), Positives = 113/272 (41%), Gaps = 46/272 (16%)

Query: 124 TLALHGLTVEDEGNYTCEFAT--FPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVA 181
           +L +  + V DEG+YTC   T   PK S     +L V   PK    +  VT ++      
Sbjct: 95  SLRIQKVDVYDEGSYTCSVQTQHEPKTS---QVYLIVQVPPKISNISSDVTVNEGSNVTL 151

Query: 182 LCISKEGRPPARISWL----SSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVT 237
           +C++  GRP   I+W     +  ++E +E  +   + G        T   SG+ +     
Sbjct: 152 VCMA-NGRPEPVITWRHLTPTGREFEGEEEYLE--ILG-------ITREQSGKYE----- 196

Query: 238 CKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDW- 296
           CK  +E      +  V ++V YPP ++ S    N       A+L C+  + P P  ++W 
Sbjct: 197 CKAANE-VSSADVKQVKVTVNYPPTITES--KSNEATTGRQASLKCEASAVPAP-DFEWY 252

Query: 297 ------STTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETP 350
                 ++ +G    S   Q S  V +  +  +   + C   N +G+  A  V+F     
Sbjct: 253 RDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYG-NYTCVAANKLGVTNASLVLF----- 306

Query: 351 NTAGAGATGGIIGGIIAAIIATAVAATGILIC 382
                G+  GI G I  A+    +AA+  L+C
Sbjct: 307 ---RPGSVRGINGSISLAVPLWLLAAS--LLC 333


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,117,102
Number of Sequences: 37866
Number of extensions: 1365567
Number of successful extensions: 7599
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 334
Number of HSP's that attempted gapping in prelim test: 6751
Number of HSP's gapped (non-prelim): 1137
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.