Guide to the Human Genome
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Search of human proteins with 10834982

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10834982 insulin-like growth factor binding protein 5 [Homo
sapiens]
         (272 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10834982 insulin-like growth factor binding protein 5 [Homo s...   572   e-163
gi|62243068 insulin-like growth factor binding protein 3 isoform...   234   6e-62
gi|62243248 insulin-like growth factor binding protein 3 isoform...   232   3e-61
gi|62243290 insulin-like growth factor binding protein 4 precurs...   180   1e-45
gi|11321593 insulin-like growth factor binding protein 6 [Homo s...   150   1e-36
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ...   142   2e-34
gi|4504615 insulin-like growth factor binding protein 1 precurso...   133   2e-31
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]            53   3e-07
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa...    52   4e-07
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo...    51   9e-07
gi|93141003 testican 3 isoform 1 [Homo sapiens]                        49   4e-06
gi|93141001 testican 3 isoform 2 [Homo sapiens]                        49   4e-06
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo...    49   4e-06
gi|5901946 endothelial cell-specific molecule 1 isoform a precur...    46   3e-05
gi|208022668 endothelial cell-specific molecule 1 isoform b prec...    46   3e-05
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]                45   9e-05
gi|115298674 nidogen 1 precursor [Homo sapiens]                        44   2e-04
gi|55770862 thyroglobulin [Homo sapiens]                               43   3e-04
gi|56090548 insulin-like growth factor binding protein-like 1 [H...    42   6e-04
gi|144953895 nidogen 2 precursor [Homo sapiens]                        39   0.004
gi|78190498 secreted modular calcium-binding protein 1 isoform 1...    39   0.004
gi|11545873 secreted modular calcium-binding protein 1 isoform 2...    39   0.004
gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ...    38   0.008
gi|4503123 connective tissue growth factor [Homo sapiens]              38   0.011
gi|22129776 HtrA serine peptidase 3 [Homo sapiens]                     38   0.011
gi|218505670 epithelial cell adhesion molecule precursor [Homo s...    37   0.018
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]       36   0.031
gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]           36   0.031
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]     36   0.031
gi|166795236 tumor-associated calcium signal transducer 2 precur...    36   0.041

>gi|10834982 insulin-like growth factor binding protein 5 [Homo
           sapiens]
          Length = 272

 Score =  572 bits (1474), Expect = e-163
 Identities = 272/272 (100%), Positives = 272/272 (100%)

Query: 1   MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA 60
           MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA
Sbjct: 1   MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA 60

Query: 61  LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE 120
           LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE
Sbjct: 61  LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE 120

Query: 121 EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA 180
           EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA
Sbjct: 121 EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA 180

Query: 181 PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI 240
           PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI
Sbjct: 181 PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI 240

Query: 241 CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE 272
           CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
Sbjct: 241 CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE 272


>gi|62243068 insulin-like growth factor binding protein 3 isoform b
           precursor [Homo sapiens]
          Length = 291

 Score =  234 bits (597), Expect = 6e-62
 Identities = 123/276 (44%), Positives = 157/276 (56%), Gaps = 34/276 (12%)

Query: 3   LLTAVLLLLAAYAGP--------AQSLGSFVHCEPCDEKALSMCPPSPLGC-ELVKEPGC 53
           L  A L LL    GP        +  LG  V CEPCD +AL+ C P P  C ELV+EPGC
Sbjct: 8   LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGC 67

Query: 54  GCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYRE----- 108
           GCC+TCAL+EGQ CG+YTERC  GLRC P  DE +PL ALL GRG+C+N  +        
Sbjct: 68  GCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYL 127

Query: 109 -----------QVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRR 157
                      + + +R +   E P+ S        PK F P H++I  +K    K  +R
Sbjct: 128 LPAPPAPGNASESEEDRSAGSVESPSVSS-THRVSDPK-FHPLHSKIIIIKKGHAKDSQR 185

Query: 158 KKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLP 217
            K+         +N +        E ++E+E GPCRR ME +L  LK    + PR V++P
Sbjct: 186 YKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIP 238

Query: 218 NCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPG 253
           NCD+KGFYK+KQC+PS+GRKRG CWCVDKYG  LPG
Sbjct: 239 NCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG 274


>gi|62243248 insulin-like growth factor binding protein 3 isoform a
           precursor [Homo sapiens]
          Length = 297

 Score =  232 bits (591), Expect = 3e-61
 Identities = 123/282 (43%), Positives = 157/282 (55%), Gaps = 40/282 (14%)

Query: 3   LLTAVLLLLAAYAGP--------AQSLGSFVHCEPCDEKALSMCPPSPLGC-ELVKEPGC 53
           L  A L LL    GP        +  LG  V CEPCD +AL+ C P P  C ELV+EPGC
Sbjct: 8   LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGC 67

Query: 54  GCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYRE----- 108
           GCC+TCAL+EGQ CG+YTERC  GLRC P  DE +PL ALL GRG+C+N  +        
Sbjct: 68  GCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYL 127

Query: 109 -----------------QVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEA 151
                            + + +R +   E P+ S        PK F P H++I  +K   
Sbjct: 128 LPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSS-THRVSDPK-FHPLHSKIIIIKKGH 185

Query: 152 VKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVP 211
            K  +R K+         +N +        E ++E+E GPCRR ME +L  LK    + P
Sbjct: 186 AKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFLNVLSP 238

Query: 212 RAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPG 253
           R V++PNCD+KGFYK+KQC+PS+GRKRG CWCVDKYG  LPG
Sbjct: 239 RGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG 280


>gi|62243290 insulin-like growth factor binding protein 4 precursor
           [Homo sapiens]
          Length = 258

 Score =  180 bits (457), Expect = 1e-45
 Identities = 109/275 (39%), Positives = 142/275 (51%), Gaps = 26/275 (9%)

Query: 1   MVLLTAVLLLLAAYAGPAQSLGS-FVHCEPCDEKALSMCPPSPLGCE-LVKEPGCGCCMT 58
           M+ L  V  LL A AGP  SLG   +HC PC E+ L+ C P P+GCE LV+EPGCGCC T
Sbjct: 1   MLPLCLVAALLLA-AGPGPSLGDEAIHCPPCSEEKLARCRP-PVGCEELVREPGCGCCAT 58

Query: 59  CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSRE 118
           CAL  G  CGVYT RC  GLRC P +  EKPLH L+HG+GVC+       +++  ++S +
Sbjct: 59  CALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCME----LAEIEAIQESLQ 114

Query: 119 HEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRII 178
             +    +    ++SP      H R    K  A  +DR     + K  G     A P   
Sbjct: 115 PSDKDEGDHPNNSFSP---CSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARP--- 168

Query: 179 SAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVY---LPNCDRKGFYKRKQCKPSRG 235
                     QG C+  +  +L+ L AS       +Y   +PNCDR G +  KQC P+  
Sbjct: 169 --------VPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALD 220

Query: 236 RKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFDSS 269
            +RG CWCVD K G+KLPG     G+  CH    S
Sbjct: 221 GQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADS 255


>gi|11321593 insulin-like growth factor binding protein 6 [Homo
           sapiens]
          Length = 240

 Score =  150 bits (378), Expect = 1e-36
 Identities = 92/268 (34%), Positives = 131/268 (48%), Gaps = 40/268 (14%)

Query: 3   LLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMT--CA 60
           LL  + LLLAA  G     G+   C  C +   + CP   +  E    P  GC     C 
Sbjct: 10  LLLLLALLLAASPG-----GALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCL 64

Query: 61  LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE 120
             EGQ CGVYT  CA GL+C P +D+E PL ALL GRG CL  ++               
Sbjct: 65  RREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARA--------------- 109

Query: 121 EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA 180
                 +AEE  +PK  +P        +A   +     +  Q +  G +   + P     
Sbjct: 110 ----PAVAEE--NPKESKP--------QAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGV 155

Query: 181 PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI 240
               Q++E GPCRRH+++ LQ+L+       + +Y+PNCD +GFY+++QC+ S+G++RG 
Sbjct: 156 ----QDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGP 211

Query: 241 CWCVDKYGMKLPGMEYVDGDFQCHTFDS 268
           CWCVD+ G  LPG    +G   C T  S
Sbjct: 212 CWCVDRMGKSLPGSPDGNGSSSCPTGSS 239


>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
           [Homo sapiens]
          Length = 328

 Score =  142 bits (359), Expect = 2e-34
 Identities = 90/305 (29%), Positives = 136/305 (44%), Gaps = 41/305 (13%)

Query: 3   LLTAVLLLLAAYAGPAQSLGSFV-HCEPCDEKALSMCPPSPLG----------------C 45
           LL  +LLLL A  G   +    +  C PC  + L+ C P P+                  
Sbjct: 20  LLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCA 79

Query: 46  ELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKS 105
           ELV+EPGCGCC  CA  EG++CGVYT RC QGLRC P    E PL AL+ G G C   + 
Sbjct: 80  ELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRD 139

Query: 106 YREQVKIERDSREHEEPTTSEMAEETYSPKI----------FRPKHTRISELKAEAVKKD 155
                  E+ +   ++ +   + E      +           +P  + + EL        
Sbjct: 140 AEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAV------ 193

Query: 156 RRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQEL-------KASPR 208
            R+K+T+     G     H  +    ++R    + PC++ ++  L+ +       +  P 
Sbjct: 194 FREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPL 253

Query: 209 MVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFD 267
               ++++PNCD+ G Y  KQCK S   +RG CWCV+   G  + G   + GD +CH F 
Sbjct: 254 EHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFY 313

Query: 268 SSNVE 272
           +   E
Sbjct: 314 NEQQE 318


>gi|4504615 insulin-like growth factor binding protein 1 precursor
           [Homo sapiens]
          Length = 259

 Score =  133 bits (334), Expect = 2e-31
 Identities = 83/265 (31%), Positives = 124/265 (46%), Gaps = 27/265 (10%)

Query: 7   VLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGC-ELVKEPGCGCCMTCALAEGQ 65
           VLLLL    G   + G+   C PC  + L++CPP    C E+ +  GCGCC  CAL  G 
Sbjct: 12  VLLLLTVQVGV--TAGAPWQCAPCSAEKLALCPPVSASCSEVTRSAGCGCCPMCALPLGA 69

Query: 66  SCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTS 125
           +CGV T RCA+GL C     E++PLHAL  G+G C+ E         E  S   E P ++
Sbjct: 70  ACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEAGS--PESPEST 127

Query: 126 EMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQ 185
           E+ EE    ++    H      +  ++  D       SK             +    +++
Sbjct: 128 EITEE----ELLDNFHLMAPSEEDHSILWDAISTYDGSK------------ALHVTNIKK 171

Query: 186 ESEQGPCRRHMEASLQELKASPRMVPRAV---YLPNCDRKGFYKRKQCKPSRGRKRGICW 242
             E  PCR  +   ++ L  +       +   YLPNC++ GFY  +QC+ S   + G+CW
Sbjct: 172 WKE--PCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCW 229

Query: 243 CVDKY-GMKLPGMEYVDGDFQCHTF 266
           CV  + G ++PG   + GD  C  +
Sbjct: 230 CVYPWNGKRIPGSPEIRGDPNCQIY 254


>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
          Length = 480

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 33/89 (37%), Positives = 41/89 (46%), Gaps = 16/89 (17%)

Query: 3  LLTAVLLLLAAYAGPAQS---------LGSFVHCEPCDEKALSMCPPSPLGCELVK-EPG 52
          LL  +LLLLAA A    S          G    CEP      + CPP P  CE  +    
Sbjct: 8  LLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEP------ARCPPQPEHCEGGRARDA 61

Query: 53 CGCCMTCALAEGQSCGVYTERCAQGLRCL 81
          CGCC  C   EG +CG+    C +GL+C+
Sbjct: 62 CGCCEVCGAPEGAACGLQEGPCGEGLQCV 90


>gi|4504619 insulin-like growth factor binding protein 7 [Homo
           sapiens]
          Length = 282

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 40/115 (34%), Positives = 51/115 (44%), Gaps = 15/115 (13%)

Query: 1   MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPP-SPLGCELVK-EPGCGCCMT 58
           ++L  A LLLL     P  S  S   C PC+  +   CPP  PLGC L +    CGCC  
Sbjct: 9   LLLGAAGLLLLLL---PLSSSSSSDTCGPCEPAS---CPPLPPLGCLLGETRDACGCCPM 62

Query: 59  CALAEGQSC---GVYTERCAQGLRCLPRQDEEKPLHALLHG----RGVCLNEKSY 106
           CA  EG+ C   G     CA G+ C+  +   K       G     GVC+ +  Y
Sbjct: 63  CARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRY 117


>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
           proteoglycan 1 precursor [Homo sapiens]
          Length = 439

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 7/63 (11%)

Query: 191 PCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMK 250
           PC+  M   +Q+L     ++    ++P C+ +G+YK  QC  S G+    CWCVDKYG +
Sbjct: 312 PCQNEMNR-IQKLSKGKSLL--GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364

Query: 251 LPG 253
           L G
Sbjct: 365 LAG 367


>gi|93141003 testican 3 isoform 1 [Homo sapiens]
          Length = 433

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 8/79 (10%)

Query: 185 QESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCV 244
           Q  +  PC+  + +++Q+ +   +++ +  Y+P CD  G+YK  QC  S G+    CWCV
Sbjct: 307 QRQQDPPCQTEL-SNIQKRQGVKKLLGQ--YIPLCDEDGYYKPTQCHGSVGQ----CWCV 359

Query: 245 DKYGMKLPGMEYVDGDFQC 263
           D+YG ++ G   ++G   C
Sbjct: 360 DRYGNEVMGSR-INGVADC 377


>gi|93141001 testican 3 isoform 2 [Homo sapiens]
          Length = 436

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 8/79 (10%)

Query: 185 QESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCV 244
           Q  +  PC+  + +++Q+ +   +++ +  Y+P CD  G+YK  QC  S G+    CWCV
Sbjct: 310 QRQQDPPCQTEL-SNIQKRQGVKKLLGQ--YIPLCDEDGYYKPTQCHGSVGQ----CWCV 362

Query: 245 DKYGMKLPGMEYVDGDFQC 263
           D+YG ++ G   ++G   C
Sbjct: 363 DRYGNEVMGSR-INGVADC 380


>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
           proteoglycan (testican) 2 isoform 2 [Homo sapiens]
          Length = 424

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 7/66 (10%)

Query: 188 EQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKY 247
           E+ PC   +E    +++ + +  P  +++P+CD  G+Y++ QC  S G     CWCVD+ 
Sbjct: 309 EKPPCLAELERI--QIQEAAKKKP-GIFIPSCDEDGYYRKMQCDQSSGD----CWCVDQL 361

Query: 248 GMKLPG 253
           G++L G
Sbjct: 362 GLELTG 367


>gi|5901946 endothelial cell-specific molecule 1 isoform a
          precursor [Homo sapiens]
          Length = 184

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 10/91 (10%)

Query: 3  LLTAVLLLLAAYAGPAQSLGSFVHC-EPCDEKALSMCPPSPLGCELVKEPGCGCCMTCAL 61
          +L    LL+ A+   A S    V C + CD    S C  SP  C+      CGCC  CA 
Sbjct: 4  VLLLTTLLVPAHLVAAWSNNYAVDCPQHCDS---SECKSSPR-CKRTVLDDCGCCRVCAA 59

Query: 62 AEGQSC-----GVYTERCAQGLRCLPRQDEE 87
            G++C     G+   +C  GLRC P   E+
Sbjct: 60 GRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90


>gi|208022668 endothelial cell-specific molecule 1 isoform b
          precursor [Homo sapiens]
          Length = 134

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 10/91 (10%)

Query: 3  LLTAVLLLLAAYAGPAQSLGSFVHC-EPCDEKALSMCPPSPLGCELVKEPGCGCCMTCAL 61
          +L    LL+ A+   A S    V C + CD    S C  SP  C+      CGCC  CA 
Sbjct: 4  VLLLTTLLVPAHLVAAWSNNYAVDCPQHCDS---SECKSSPR-CKRTVLDDCGCCRVCAA 59

Query: 62 AEGQSC-----GVYTERCAQGLRCLPRQDEE 87
            G++C     G+   +C  GLRC P   E+
Sbjct: 60 GRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90


>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
          Length = 1036

 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 34/88 (38%), Positives = 43/88 (48%), Gaps = 16/88 (18%)

Query: 1  MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCE-LVKEPGCGCCMTC 59
          +V L  +LLLLA     A      + C PCDE   S C   P  C   + +  CGCC TC
Sbjct: 17 LVSLLGLLLLLARSGTRA------LVCLPCDE---SKCE-EPRNCPGSIVQGVCGCCYTC 66

Query: 60 ALAEGQSC----GVYTERCAQGLRCLPR 83
          A    +SC    G+Y   C +GLRC+ R
Sbjct: 67 ASQRNESCGGTFGIY-GTCDRGLRCVIR 93


>gi|115298674 nidogen 1 precursor [Homo sapiens]
          Length = 1247

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 186 ESEQGPCRRHMEASLQELKASP--RMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWC 243
           E E+  C+   E  L    A+   R +P  +++P CD  G Y   QC  S     G CWC
Sbjct: 843 EVEKTRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGS----TGYCWC 898

Query: 244 VDKYGMKLPG 253
           VD+ G ++ G
Sbjct: 899 VDRDGREVEG 908


>gi|55770862 thyroglobulin [Homo sapiens]
          Length = 2768

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 6/55 (10%)

Query: 211 PRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHT 265
           P  +++P+C  +G Y+  QC        G CWCV+ +G +LPG     G  +C T
Sbjct: 612 PERLFVPSCTTEGSYEDVQCFS------GECWCVNSWGKELPGSRVRGGQPRCPT 660



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 5/39 (12%)

Query: 215 YLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPG 253
           Y+P+C R G Y+  QC+       G CWCVD  G ++ G
Sbjct: 315 YVPSCRRNGDYQAVQCQTE-----GPCWCVDAQGKEMHG 348



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 4/39 (10%)

Query: 215  YLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPG 253
            Y+P CD  G ++  QC    G     CWCVD+ G  +PG
Sbjct: 1027 YMPQCDAFGSWEPVQCHAGTGH----CWCVDEKGGFIPG 1061



 Score = 35.0 bits (79), Expect = 0.070
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 4/49 (8%)

Query: 215 YLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQC 263
           YLP C   G Y   QC   + +    CWCVD  GM++ G   +    +C
Sbjct: 116 YLPQCQDSGDYAPVQCDVQQVQ----CWCVDAEGMEVYGTRQLGRPKRC 160



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 202 ELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDF 261
           EL+     + +A Y+P C   G ++  QC+ + GR    CWCV   G ++ G        
Sbjct: 35  ELQRETAFLKQADYVPQCAEDGSFQTVQCQ-NDGRS---CWCVGANGSEVLGSRQPGRPV 90

Query: 262 QCHTF 266
            C +F
Sbjct: 91  ACLSF 95



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 5/52 (9%)

Query: 215  YLPNCDRK-GFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHT 265
            Y+P C  + G +   QC  ++G     CWCV   G ++PG     G   C +
Sbjct: 1165 YVPACRAEDGGFSPVQCDQAQGS----CWCVMDSGEEVPGTRVTGGQPACES 1212



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 10/76 (13%)

Query: 181 PEMRQESEQGPCRRHME---ASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRK 237
           P  R    Q  C    E   A +Q L  S +     +++P C  +G +   QC  S    
Sbjct: 647 PGSRVRGGQPRCPTDCEKQRARMQSLMGS-QPAGSTLFVPACTSEGHFLPVQCFNSE--- 702

Query: 238 RGICWCVDKYGMKLPG 253
              C+CVD  G  +PG
Sbjct: 703 ---CYCVDAEGQAIPG 715


>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
           sapiens]
          Length = 278

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 9/103 (8%)

Query: 1   MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPL-GCELVKEPGCGCCMTC 59
           ++LL  +L  L+   G     G    C PC  +      P P  G   + E  CGCC  C
Sbjct: 12  LLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISALDE--CGCCARC 69

Query: 60  ALAEGQSCGVYT-ERCAQGLRCLPRQDEEKPLHALLHGRGVCL 101
             AEG SCG     RC  GL C  +     P      G G+C+
Sbjct: 70  LGAEGASCGGRAGGRCGPGLVCASQAAGAAP-----EGTGLCV 107


>gi|144953895 nidogen 2 precursor [Homo sapiens]
          Length = 1375

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 215  YLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCH 264
            ++P CD +G +   QC  S G     CWCVD  G ++PG +   G    H
Sbjct: 959  HIPQCDEQGNFLPLQCHGSTG----FCWCVDPDGHEVPGTQTPPGSTPPH 1004



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 192  CRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKL 251
            C R  E  L+    +PR      Y+P CD  G +   QC      K   CWCVDK G ++
Sbjct: 1019 CERWRENLLEHYGGTPR---DDQYVPQCDDLGHFIPLQCHG----KSDFCWCVDKDGREV 1071

Query: 252  PG 253
             G
Sbjct: 1072 QG 1073


>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
           [Homo sapiens]
          Length = 435

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 8/72 (11%)

Query: 183 MRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICW 242
           +R   +   C +  +++L+E + +PR     + +P C   G YK  QC  S     G CW
Sbjct: 218 IRNSEKVYSCDQERQSALEEAQQNPR---EGIVIPECAPGGLYKPVQCHQS----TGYCW 270

Query: 243 CV-DKYGMKLPG 253
           CV    G  LPG
Sbjct: 271 CVLVDTGRPLPG 282



 Score = 35.0 bits (79), Expect = 0.070
 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 8/69 (11%)

Query: 185 QESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCV 244
           +++ Q  CR     +L++ K        AV++P C   G + + QC        G CWCV
Sbjct: 88  KDAGQSKCRLERAQALEQAKKPQE----AVFVPECGEDGSFTQVQCH----TYTGYCWCV 139

Query: 245 DKYGMKLPG 253
              G  + G
Sbjct: 140 TPDGKPISG 148


>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
           [Homo sapiens]
          Length = 434

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 8/72 (11%)

Query: 183 MRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICW 242
           +R   +   C +  +++L+E + +PR     + +P C   G YK  QC  S     G CW
Sbjct: 218 IRNSEKVYSCDQERQSALEEAQQNPR---EGIVIPECAPGGLYKPVQCHQS----TGYCW 270

Query: 243 CV-DKYGMKLPG 253
           CV    G  LPG
Sbjct: 271 CVLVDTGRPLPG 282



 Score = 35.0 bits (79), Expect = 0.070
 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 8/69 (11%)

Query: 185 QESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCV 244
           +++ Q  CR     +L++ K        AV++P C   G + + QC        G CWCV
Sbjct: 88  KDAGQSKCRLERAQALEQAKKPQE----AVFVPECGEDGSFTQVQCH----TYTGYCWCV 139

Query: 245 DKYGMKLPG 253
              G  + G
Sbjct: 140 TPDGKPISG 148


>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
          [Homo sapiens]
          Length = 250

 Score = 38.1 bits (87), Expect = 0.008
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 2/45 (4%)

Query: 39 PPSPLGCELVKEPGCGCCMTCALAEGQSCG-VYTERCAQGLRCLP 82
          P  PLG  LV + GCGCC  CA   G+ C  ++    +QGL C P
Sbjct: 37 PRCPLGVPLVLD-GCGCCRVCARRLGEPCDQLHVCDASQGLVCQP 80


>gi|4503123 connective tissue growth factor [Homo sapiens]
          Length = 349

 Score = 37.7 bits (86), Expect = 0.011
 Identities = 27/68 (39%), Positives = 32/68 (47%), Gaps = 8/68 (11%)

Query: 6  AVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQ 65
          A ++LLA  + PA        C   DE A    P  P G  LV + GCGCC  CA   G+
Sbjct: 12 AFVVLLALCSRPAVGQNCSGPCRCPDEPA----PRCPAGVSLVLD-GCGCCRVCAKQLGE 66

Query: 66 SCGVYTER 73
           C   TER
Sbjct: 67 LC---TER 71


>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
          Length = 453

 Score = 37.7 bits (86), Expect = 0.011
 Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 5/80 (6%)

Query: 4  LTAVLLLLAAYAGPAQSLGSFVHCEPCDEKA-LSMCPPSPLGCELVKEPGCGCCMTCALA 62
          + A  LLLAA A  A +L       PC  +  +S CP        V +  C CC+ CA +
Sbjct: 1  MQARALLLAALA--ALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDL-CNCCLVCAAS 57

Query: 63 EGQSC-GVYTERCAQGLRCL 81
          EG+ C G     C + L C+
Sbjct: 58 EGEPCGGPLDSPCGESLECV 77


>gi|218505670 epithelial cell adhesion molecule precursor [Homo
           sapiens]
          Length = 314

 Score = 37.0 bits (84), Expect = 0.018
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 12/62 (19%)

Query: 196 MEASLQELKASPRMVPRA-------VYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYG 248
           M+A +   K   R  P         +Y P+CD  G +K KQC  +      +CWCV+  G
Sbjct: 69  MKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGT-----SMCWCVNTAG 123

Query: 249 MK 250
           ++
Sbjct: 124 VR 125


>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
          Length = 357

 Score = 36.2 bits (82), Expect = 0.031
 Identities = 20/68 (29%), Positives = 27/68 (39%), Gaps = 13/68 (19%)

Query: 21 LGSFVHCEPCDEKALSMCPPSPLGCE---LVKEPGCGCCMTCALAEGQSC---------- 67
          LG     + C  +    CP +P  C         GC CC+ CA   G+SC          
Sbjct: 26 LGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESS 85

Query: 68 GVYTERCA 75
          G+Y +R A
Sbjct: 86 GLYCDRSA 93


>gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]
          Length = 476

 Score = 36.2 bits (82), Expect = 0.031
 Identities = 31/85 (36%), Positives = 40/85 (47%), Gaps = 10/85 (11%)

Query: 3  LLTAVLLLLAA--YAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPG---CGCCM 57
          LL  +LLLL    +AG A+ L +   C    +   + CP  P  C L   P    C CC 
Sbjct: 15 LLPGLLLLLVPVLWAG-AEKLHTQPSCPAVCQP--TRCPALPT-CALGTTPVFDLCRCCR 70

Query: 58 TCALAEGQSC-GVYTERCAQGLRCL 81
           C  AE + C G   + CA GL+CL
Sbjct: 71 VCPAAEREVCGGAQGQPCAPGLQCL 95


>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
          Length = 457

 Score = 36.2 bits (82), Expect = 0.031
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 8/63 (12%)

Query: 192 CRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCV-DKYGMK 250
           C +  +++L+E K         V +P C   G YK  QC PS     G CWCV    G  
Sbjct: 227 CDQEHQSALEEAKQPKN---DNVVIPECAHGGLYKPVQCHPS----TGYCWCVLVDTGRP 279

Query: 251 LPG 253
           +PG
Sbjct: 280 IPG 282



 Score = 32.3 bits (72), Expect = 0.45
 Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 4/40 (10%)

Query: 214 VYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPG 253
           V++P C+  G Y + QC        G CWCV   G  + G
Sbjct: 108 VFIPECNDDGTYSQVQCH----SYTGYCWCVTPNGRPISG 143


>gi|166795236 tumor-associated calcium signal transducer 2 precursor
           [Homo sapiens]
          Length = 323

 Score = 35.8 bits (81), Expect = 0.041
 Identities = 13/37 (35%), Positives = 23/37 (62%), Gaps = 5/37 (13%)

Query: 214 VYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMK 250
           +Y P+CD +G +K +QC      +  +CWCV+  G++
Sbjct: 103 LYDPDCDPEGRFKARQC-----NQTSVCWCVNSVGVR 134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,826,208
Number of Sequences: 37866
Number of extensions: 594864
Number of successful extensions: 1925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 1820
Number of HSP's gapped (non-prelim): 127
length of query: 272
length of database: 18,247,518
effective HSP length: 101
effective length of query: 171
effective length of database: 14,423,052
effective search space: 2466341892
effective search space used: 2466341892
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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