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Search of human proteins with 10140845
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
(1005 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 2057 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 1221 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 1212 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 1189 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 1170 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 1169 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 1147 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 1039 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 1033 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 1033 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 991 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 911 0.0
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 908 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 869 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 850 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 739 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 726 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 662 0.0
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 306 6e-83
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 217 5e-56
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 217 5e-56
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 210 5e-54
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 210 6e-54
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... 210 6e-54
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 210 6e-54
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 210 6e-54
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs... 209 1e-53
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs... 209 1e-53
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 208 2e-53
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi... 208 2e-53
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
Length = 1005
Score = 2057 bits (5329), Expect = 0.0
Identities = 1005/1005 (100%), Positives = 1005/1005 (100%)
Query: 1 MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV 60
MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
Sbjct: 1 MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV 60
Query: 61 DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE 120
DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
Sbjct: 61 DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE 120
Query: 121 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG 180
TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
Sbjct: 121 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG 180
Query: 181 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER 240
FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
Sbjct: 181 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER 240
Query: 241 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA 300
DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
Sbjct: 241 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA 300
Query: 301 APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI 360
APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
Sbjct: 301 APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI 360
Query: 361 TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD 420
TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
Sbjct: 361 TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD 420
Query: 421 LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK 480
LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK
Sbjct: 421 LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK 480
Query: 481 DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT 540
DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT
Sbjct: 481 DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT 540
Query: 541 RTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHP 600
RTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHP
Sbjct: 541 RTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHP 600
Query: 601 PGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR 660
PGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR
Sbjct: 601 PGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR 660
Query: 661 DVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGS 720
DVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGS
Sbjct: 661 DVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGS 720
Query: 721 LDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFG 780
LDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFG
Sbjct: 721 LDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFG 780
Query: 781 LSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW 840
LSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW
Sbjct: 781 LSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW 840
Query: 841 NMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
NMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE
Sbjct: 841 NMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
Query: 901 SLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLG 960
SLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLG
Sbjct: 901 SLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLG 960
Query: 961 MVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL 1005
MVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL
Sbjct: 961 MVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL 1005
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 1221 bits (3159), Expect = 0.0
Identities = 586/994 (58%), Positives = 746/994 (75%), Gaps = 23/994 (2%)
Query: 12 LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
LW + AA T +++ EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 40 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
Query: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
QVC VM NQNNWL TSW+ +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 100 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
Query: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
G + +E+Q++KIDTIAADESFT DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 160 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
Query: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250
C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS + PKM+CSAE
Sbjct: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279
Query: 251 GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310
GEWLVPIGKC+C AGYEE+ C C GF+K++P Q C +CPPHS++ A+ +C C+
Sbjct: 280 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339
Query: 311 LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370
Y+R DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y C++C
Sbjct: 340 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399
Query: 371 WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
CE CG R++P+Q+ L S+++ +LLAH NY+F IEAVNGVSDLSP R+
Sbjct: 400 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459
Query: 431 VNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTL 490
VN+TTNQAAPS V +++ + + S+SL WQEP++PNGIILEYEIKY+EKD+E SY+ +
Sbjct: 460 VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTII 518
Query: 491 KAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKP-RPRYDTRTIVWICLT 549
K+ T T GLKP + YVFQ+RART+AG G FS+ E ET D I I ++
Sbjct: 519 KSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVS 578
Query: 550 LITGLVVLLLLL--ICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEP 607
+ G+++L +++ + R CGYSKA QD +EEKMH+ NG KLP
Sbjct: 579 VTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHI-------------KLPGV 625
Query: 608 QFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIK 667
+ Y +PHTYE+P +A F +EIEAS I IE++IG+G+ GEVC GRL++PG+R++PVAIK
Sbjct: 626 RTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIK 685
Query: 668 ALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRT 727
LK GYTE+QRRDFL EASIMGQFDHPNII LEGVVT+ + MIVTEYMENGSLDTFL+
Sbjct: 686 TLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKK 745
Query: 728 HDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLED 787
+DGQFT++QLVGMLRG+ AGM+YLSD+GYVHRDLAARN+L++SNLVCKVSDFGLSRVLED
Sbjct: 746 NDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLED 805
Query: 788 DPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDV 847
DP+AAYTT GGKIPIRWTAPEAIAFR F+SASDVWS+G+VMWEV++YGERPYW MTN+DV
Sbjct: 806 DPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDV 865
Query: 848 ISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATAT 907
I +VEEGYRLP+PM CP AL+QLMLDCW K+R RP+F +IV++LD LIR+P SL+
Sbjct: 866 IKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVN 925
Query: 908 VSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNA 967
S V + G G +VG+WL++I+MGRY + F GYSS+ V ++
Sbjct: 926 AS-----CRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 980
Query: 968 QDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
+D+R LG+TL+GHQKKI+ S+Q M+ QL + P
Sbjct: 981 EDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVP 1014
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 1212 bits (3137), Expect = 0.0
Identities = 587/1016 (57%), Positives = 747/1016 (73%), Gaps = 45/1016 (4%)
Query: 12 LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
LW + AA T +++ EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 40 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
Query: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
QVC VM NQNNWL TSW+ +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 100 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
Query: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
G + +E+Q++KIDTIAADESFT DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 160 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
Query: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250
C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS + PKM+CSAE
Sbjct: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279
Query: 251 GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310
GEWLVPIGKC+C AGYEE+ C C GF+K++P Q C +CPPHS++ A+ +C C+
Sbjct: 280 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339
Query: 311 LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370
Y+R DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y C++C
Sbjct: 340 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399
Query: 371 WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
CE CG R++P+Q+ L S+++ +LLAH NY+F IEAVNGVSDLSP R+
Sbjct: 400 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459
Query: 431 VNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTL 490
VN+TTNQAAPS V +++ + + S+SL WQEP++PNGIILEYEIKY+EKD+E SY+ +
Sbjct: 460 VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTII 518
Query: 491 KAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKP-RPRYDTRTIVWICLT 549
K+ T T GLKP + YVFQ+RART+AG G FS+ E ET D I I ++
Sbjct: 519 KSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVS 578
Query: 550 LITGLVVLLLLL------------------ICKKRH------CGYSKAFQDSDEEKMHYQ 585
+ G+++L +++ +C H CGYSKA QD +EEKMH+
Sbjct: 579 VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH 638
Query: 586 NGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGD 645
NG KLP + Y +PHTYE+P +A F +EIEAS I IE++IG+G+
Sbjct: 639 NGHI-------------KLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGE 685
Query: 646 SGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTR 705
GEVC GRL++PG+R++PVAIK LK GYTE+QRRDFL EASIMGQFDHPNII LEGVVT+
Sbjct: 686 FGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTK 745
Query: 706 GRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARN 765
+ MIVTEYMENGSLDTFL+ +DGQFT++QLVGMLRG+ AGM+YLSD+GYVHRDLAARN
Sbjct: 746 SKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARN 805
Query: 766 VLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFG 825
+L++SNLVCKVSDFGLSRVLEDDP+AAYTT GGKIPIRWTAPEAIAFR F+SASDVWS+G
Sbjct: 806 ILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYG 865
Query: 826 VVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRF 885
+VMWEV++YGERPYW MTN+DVI +VEEGYRLP+PM CP AL+QLMLDCW K+R RP+F
Sbjct: 866 IVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKF 925
Query: 886 SQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMG 945
+IV++LD LIR+P SL+ S V + G G +VG+WL++I+MG
Sbjct: 926 DEIVNMLDKLIRNPSSLKTLVNAS-----CRVSNLLAEHSPLGSGAYRSVGEWLEAIKMG 980
Query: 946 RYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
RY + F GYSS+ V ++ +D+R LG+TL+GHQKKI+ S+Q M+ QL + P
Sbjct: 981 RYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVP 1036
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 1189 bits (3076), Expect = 0.0
Identities = 577/995 (57%), Positives = 736/995 (73%), Gaps = 38/995 (3%)
Query: 21 AATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQ 80
A T + A EV LLD+ + W++ P +GW+ I+ +DE++ PI TYQVC VM PNQ
Sbjct: 22 AHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQ 81
Query: 81 NNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQES 140
NNWLRT+W+ + A+R++ E+KFTLRDCNS+PGVLGTCKETFNLYY E+D D G + +E+
Sbjct: 82 NNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIREN 141
Query: 141 QFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIY 200
++KIDTIAADESFT DLG R++KLNTEVR +GPLSK+GFYLAFQD+GAC+A++S+++Y
Sbjct: 142 LYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVY 201
Query: 201 YKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIG 258
YKKC +++ NLA F + VTG++ SSLVEVRG CV +EE + P+M+CSAEGEWLVPIG
Sbjct: 202 YKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIG 261
Query: 259 KCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAAL 318
KC+C AGY+++ D C C GFYKS+ D C+RCP HS S + C C+ YYRA
Sbjct: 262 KCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPS 321
Query: 319 DPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEA 378
DPP ACTRPPSAP NLI ++N T+V+LEW+PP D GGR+D+TY +C+RC W C
Sbjct: 322 DPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVP 381
Query: 379 CGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438
CGS ++PQQT L + V +LLAH NY+F +EAVNGVSDLS R A V+ITT QA
Sbjct: 382 CGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQA 441
Query: 439 APSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRAT 498
APSQV + +ER Q SV L WQEPE PNG+I EYEIKYYEKD+ ++YST+K +T A+
Sbjct: 442 APSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSAS 501
Query: 499 VSGLKPGTRYVFQVRARTSAGCGRFSQAMEVET-----GK----PRPRYDTRTIVWICLT 549
++ LKPGT YVFQ+RA T+AG G +S ++V T GK + ++ I +
Sbjct: 502 INNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVV 561
Query: 550 LITGLVVLLLLL---ICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
+ G ++L+ ++ I +RHCGYSKA Q+ DEE L H K P
Sbjct: 562 AVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEE--------------LYFHF---KFPG 604
Query: 607 PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
+ Y +P TYE+P RA F +E++AS I IE++IG+G+ GEVC GRL++PG+RDV VAI
Sbjct: 605 TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAI 664
Query: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
K LK GYTE+QRRDFL EASIMGQFDHPN++ LEGVVTRG+ MIV E+MENG+LD FLR
Sbjct: 665 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724
Query: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
HDGQFT++QLVGMLRG+ AGMRYL+D+GYVHRDLAARN+LV+SNLVCKVSDFGLSRV+E
Sbjct: 725 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIE 784
Query: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
DDP+A YTTTGGKIP+RWTAPEAI +R F+SASDVWS+G+VMWEV++YGERPYW+M+N+D
Sbjct: 785 DDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 844
Query: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRA-T 905
VI ++EEGYRLPAPM CP LHQLMLDCW K+RA+RP+F QIV +LD +IR+P SL+
Sbjct: 845 VIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPL 904
Query: 906 ATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRM 965
T SR P ++ D +VG+WL +I+M RY+D+F A GY+SL V RM
Sbjct: 905 GTCSRPISPLLDQNTPDFT------TFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARM 958
Query: 966 NAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQG 1000
+DV +LGITL+GHQKKI+ SIQTMRAQ+ G
Sbjct: 959 TIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHG 993
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 1170 bits (3027), Expect = 0.0
Identities = 566/977 (57%), Positives = 722/977 (73%), Gaps = 32/977 (3%)
Query: 31 EVNLLDTSTIHGDWGWLTYPAHG-WDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWV 89
EV LLD+ ++ G+ GW+ P G W+ ++ +DE PI TYQVCNVM P+QNNWLRT W+
Sbjct: 30 EVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWI 89
Query: 90 PRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIA 149
R+GA+RVY EIKFTLRDCNS+PGV+GTCKETFNLYY ESD D +E+QF+KIDTIA
Sbjct: 90 TREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIA 149
Query: 150 ADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVR 209
ADESFT D+G R +KLNTE+R VGPLSK+GFYLAFQD+GAC+A++S+R++YKKCP VR
Sbjct: 150 ADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVR 209
Query: 210 NLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEER 269
NLA F + +TGAD+SSLVEVRG CV +SEE+D PKMYC A+GEWLVPIG C+C+AG+EER
Sbjct: 210 NLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEER 269
Query: 270 RDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPP 329
C AC++G+YK+ D CA+CPPHS+S A +C CD ++RA D S CTRPP
Sbjct: 270 SGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPP 329
Query: 330 SAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWA-LSRCEACGSGTRFVPQ 388
SAP+NLIS+VN TSV LEW+ P + GGR DI+YN VC++C S+C CGSG + PQ
Sbjct: 330 SAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQ 389
Query: 389 QTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQ 448
Q L + + +LLAH NY+F I AVNGVS +P P ++ V +TTNQAAPS + +++
Sbjct: 390 QNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIALVQA 449
Query: 449 ERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRY 508
+ + SV+L W EP++PNG+ILEYE+KYYEKD+ +SY ++ + GL P T Y
Sbjct: 450 KEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSY 509
Query: 509 VFQVRARTSAGCGRFSQAMEVETGK-PRPRYDTRTIVWICLTLITGLVVLLLLLIC---- 563
VF VRART+AG G FS+ +EV T P + L ++G VVL+++LI
Sbjct: 510 VFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVI 569
Query: 564 KKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAG 623
+R YSKA Q++DEEK H G + Y +P TYE+P +A
Sbjct: 570 SRRRSKYSKAKQEADEEK-HLNQGV-------------------RTYVDPFTYEDPNQAV 609
Query: 624 RSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLS 683
R F +EI+AS I IEK+IG G+ GEVC GRL+VPG+R++ VAIK LKAGYT++QRRDFLS
Sbjct: 610 REFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLS 669
Query: 684 EASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRG 743
EASIMGQFDHPNII LEGVVT+ + MI+TEYMENGSLD FLR +DG+FT++QLVGMLRG
Sbjct: 670 EASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRG 729
Query: 744 VGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIR 803
+G+GM+YLSD+ YVHRDLAARN+LV+SNLVCKVSDFG+SRVLEDDP+AAYTT GGKIPIR
Sbjct: 730 IGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIR 789
Query: 804 WTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGC 863
WTAPEAIA+R F+SASDVWS+G+VMWEV++YGERPYW+M+N+DVI ++EEGYRLP PM C
Sbjct: 790 WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDC 849
Query: 864 PHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDL 923
P ALHQLMLDCW K+R+ RP+F QIV++LD LIR+P SL+ T T S P A +
Sbjct: 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDP---- 905
Query: 924 RGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKK 983
++VGDWL +I+M RY+D+F A GY++L V+ +N +D+ +GIT + HQ K
Sbjct: 906 -SSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNK 964
Query: 984 ILGSIQTMRAQLTSTQG 1000
IL S+Q MR Q+ G
Sbjct: 965 ILSSVQAMRTQMQQMHG 981
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapiens]
Length = 983
Score = 1169 bits (3024), Expect = 0.0
Identities = 558/975 (57%), Positives = 730/975 (74%), Gaps = 27/975 (2%)
Query: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
EVNLLD+ TI G+ GW++YP+HGW+ I+ VDE + PI TYQVCNVM +QNNWLRT+WVP
Sbjct: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
Query: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAA 150
R+ A+++Y E+KFTLRDCNS+P VLGTCKETFNLYY+ESD D G +E QF KIDTIAA
Sbjct: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAA 148
Query: 151 DESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRN 210
DESFT DLG R LKLNTE+R VGP++K+GFYLAFQD+GAC+A++S+R+Y+KKCP V+N
Sbjct: 149 DESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKN 208
Query: 211 LAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERR 270
LA F + V DS SLVEVRG CV +S+E D P+MYCS EGEWLVPIGKC C+AGYEER
Sbjct: 209 LAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERG 267
Query: 271 DACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPS 330
C AC GFYK+ G+ CA+CPPHS + + C C+ +Y+RA DPPS ACTRPPS
Sbjct: 268 FMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPS 327
Query: 331 APVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQT 390
+P N+IS++N TSV L+W+ PLD GGR D+T+N +C++C W + +CE C RF+P+Q
Sbjct: 328 SPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
Query: 391 SLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQER 450
L ++ V +LLAH NY+F I+AVNGVS+LS PR+ A V+ITTNQAAPS V+ I+++R
Sbjct: 388 GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
Query: 451 AGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVF 510
+ S+SL WQEPE PNGIIL+YE+KYYEK ++ SY+ L+A T T+S LKP T YVF
Sbjct: 448 TSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVF 507
Query: 511 QVRARTSAGCGRFSQAMEVETGKPRPRY--DTRTIVWICLTLITGLVVLLLLL-ICKKRH 567
Q+RART+AG G S+ E ET ++ +V I ++ +++L +++ + R
Sbjct: 508 QIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVLIGRF 567
Query: 568 CGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFT 627
CGY K+ +DE+++H+ NG KLP + Y +PHTYE+P +A F
Sbjct: 568 CGY-KSKHGADEKRLHFGNGHL-------------KLPGLRTYVDPHTYEDPTQAVHEFA 613
Query: 628 REIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASI 687
+E++A+ I I+K++G+G+ GEVC GRL++P ++++ VAIK LK GYTE+QRRDFL EASI
Sbjct: 614 KELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASI 673
Query: 688 MGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAG 747
MGQFDHPNIIRLEGVVT+ + MIVTEYMENGSLD+FLR HD QFT++QLVGMLRG+ +G
Sbjct: 674 MGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASG 733
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M+YLSD+GYVHRDLAARN+L++SNLVCKVSDFGLSRVLEDDP+AAYTT GGKIPIRWT+P
Sbjct: 734 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSP 793
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EAIA+R F+SASDVWS+G+V+WEV++YGERPYW M+N+DVI +V+EGYRLP PM CP AL
Sbjct: 794 EAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAAL 853
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFV-RSCFDLRGG 926
+QLMLDCW KDR RP+F QIVS+LD LIR+P SL+ + + P + +S D+
Sbjct: 854 YQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTF 913
Query: 927 SGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILG 986
T GDWL+ + ++ F YSS + +++ D++ +G+T++G QKKI+
Sbjct: 914 R------TTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIIS 967
Query: 987 SIQTMRAQLTSTQGP 1001
SI+ + Q S GP
Sbjct: 968 SIKALETQ--SKNGP 980
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 1147 bits (2968), Expect = 0.0
Identities = 557/1039 (53%), Positives = 723/1039 (69%), Gaps = 86/1039 (8%)
Query: 24 CVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNW 83
C + +V LLDT+T+ G+ GW TYP +GWD+I E+DE +PIHTYQVCNVM PNQNNW
Sbjct: 121 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW 180
Query: 84 LRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFL 143
LRT+W+ RD A+++Y E+KFTLRDCNS+P VLGTCKETFNL+Y+ESD G + +Q+
Sbjct: 181 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT 240
Query: 144 KIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKK 203
KIDTIAADESFT DLG R LKLNTE+R VGP+ ++GFYLAFQDIGAC+A++S+R++YKK
Sbjct: 241 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK 300
Query: 204 CPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCS 263
CP VRNLA F + + DSSSLVEVRG CV+ +EERDTPK+YC A+G+WLVP+G+C+CS
Sbjct: 301 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS 360
Query: 264 AGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323
GYEE +C AC GFYK+ G+ C++CPPHS + A C C+ Y+RA DPPS
Sbjct: 361 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM 420
Query: 324 ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383
ACTRPPSAP N++ ++N T++ LEW+PP D GGR D+TY+ +C++C S+CE CG G
Sbjct: 421 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL 480
Query: 384 RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQV 443
RF+P+ T L+ S++V + ++H+NY+F IEA+NGVS+LS P+ + +TT+Q APS +
Sbjct: 481 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI 540
Query: 444 VVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLK 503
V+R++ A Q S++L WQ P NG IL+YEIKYYEK+ E +YS+ ++ ++GLK
Sbjct: 541 GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK 600
Query: 504 PGTRYVFQVRARTSAGCGRFSQAMEVETGKPRP--RYDTRTIVWICLTLITG---LVVLL 558
P T+YVF +R RT+ G +SQ E ETG + I+ I + G LV+L
Sbjct: 601 PATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILT 660
Query: 559 LLLICKKRHCGYSKAFQDSDEEKM-HYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYE 617
L + R Y KA S+E++ H QNG + P + Y +P TYE
Sbjct: 661 LFFLITGRCQWYIKAKMKSEEKRRNHLQNGHL-------------RFPGIKTYIDPDTYE 707
Query: 618 EPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQ 677
+P A F +EI+ SRI IE++IG+G+ GEVC GRL+ PG+R++PVAIK LK G+ +RQ
Sbjct: 708 DPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQ 767
Query: 678 RRDFLSEASIMGQFDHPNIIRLEGVVTR-------------------------------- 705
RRDFL EASIMGQFDHPNIIRLEGVVT+
Sbjct: 768 RRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPG 827
Query: 706 ----------GRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLG 755
GR MIV EYMENGSLD+FLR HDG FT++QLVGMLRG+ +GM+YLSD+G
Sbjct: 828 GGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMG 887
Query: 756 YVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTF 815
YVHRDLAARN+LV+SNLVCKVSDFGLSRVLEDDP+AAYTTTGGKIPIRWTAPEAIA+R F
Sbjct: 888 YVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKF 947
Query: 816 SSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCW 875
SSASD WS+G+VMWEV++YGERPYW M+N+DVI S+EEGYRLPAPMGCP +LHQLML CW
Sbjct: 948 SSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCW 1007
Query: 876 HKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPP---------PAFVRSCFDLRGG 926
K+R RP+F+ IVS LD LIR+P +L P P FV
Sbjct: 1008 QKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFV--------- 1058
Query: 927 SGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILG 986
TVGDWLDSI+MG+Y+++F A G+++ ++ RM+ D+R +G+ L+GHQ++I+
Sbjct: 1059 -------TVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVS 1111
Query: 987 SIQTMRAQLTSTQGPRRHL 1005
SIQT+R + Q H+
Sbjct: 1112 SIQTLRLHMMHIQEKGFHV 1130
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 1039 bits (2687), Expect = 0.0
Identities = 519/987 (52%), Positives = 688/987 (69%), Gaps = 35/987 (3%)
Query: 26 SAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLR 85
+ A E L+DT T + GW PA GW+ ++ DE+ I TYQVCNV PNQNNWL
Sbjct: 14 AVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLL 73
Query: 86 TSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLG----ASTQESQ 141
T+++ R GA R+Y E++FT+RDC+S+P V G+CKETFNLYY E+D + A E+
Sbjct: 74 TTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAP 133
Query: 142 FLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYY 201
+LK+DTIAADESF+ D G R +K+NTEVRS GPL++ GFYLAFQD GAC+++LS+R+++
Sbjct: 134 YLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFF 193
Query: 202 KKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKC 260
KKCP++V+N A F E +TGA+S+SLV RG C+ ++EE D P K+YC+ +GEW+VPIG+C
Sbjct: 194 KKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRC 253
Query: 261 VCSAGYE-ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALD 319
C GYE E AC AC G +K++ + C+ CP +S S A A+ C C YYRA D
Sbjct: 254 TCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFD 313
Query: 320 PPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEAC 379
PP ACT PS P N+IS VN TS+ LEW PP + GGR D+TYN +C++C C C
Sbjct: 314 PPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRC 373
Query: 380 GSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAA 439
FVP+Q L + + +++L AH Y+F I+A+NGVS SP P + VNITTNQAA
Sbjct: 374 DDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAA 433
Query: 440 PSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATV 499
PS V ++ Q A S++L W +PEQPNGIIL+YEI+YYEK+ + S ++ T A +
Sbjct: 434 PSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARI 493
Query: 500 SGLKPGTRYVFQVRARTSAGCGRFSQAMEVET-----GKPRPRYDTRTIVWICLTLITGL 554
GL+PG YV QVRART AG G+FS M +T K R I + +
Sbjct: 494 DGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFV 553
Query: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
V L+ + I R YSK SD+ + HY G+ P + + Y +P
Sbjct: 554 VSLVAISIVCSRKRAYSKEAVYSDKLQ-HYSTGRGSPGM--------------KIYIDPF 598
Query: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
TYE+P A R F +EI+ S + IE++IG+G+ GEV GRL++PG+R++ VAIK LKAGY+
Sbjct: 599 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYS 658
Query: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
E+QRRDFLSEASIMGQFDHPNIIRLEGVVT+ R MI+TE+MENG+LD+FLR +DGQFT+
Sbjct: 659 EKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTV 718
Query: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD-PDAAY 793
+QLVGMLRG+ AGM+YL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSR L+DD D Y
Sbjct: 719 IQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTY 778
Query: 794 TTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE 852
T++ GGKIP+RWTAPEAIA+R F+SASDVWS+G+VMWEV+++GERPYW+M+N+DVI+++E
Sbjct: 779 TSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIE 838
Query: 853 EGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCP 912
+ YRLP PM CP ALHQLMLDCW KDR RPRF++IV+ LD +IR+P SL+ AT++ P
Sbjct: 839 QDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVP 898
Query: 913 -PPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVR 971
P RS D + TV DWL +I+M +YRD F G++SL +V +M ++D+
Sbjct: 899 SQPLLDRSIPDFTAFT------TVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLL 952
Query: 972 ALGITLMGHQKKILGSIQTMRAQLTST 998
+GITL GHQKKIL SI +MR Q++ +
Sbjct: 953 RIGITLAGHQKKILNSIHSMRVQISQS 979
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 1033 bits (2672), Expect = 0.0
Identities = 509/988 (51%), Positives = 689/988 (69%), Gaps = 43/988 (4%)
Query: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
E L+D++T + GW+ +P GW+ ++ DE+ I TYQVCNV +QNNWLRT ++
Sbjct: 20 EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
Query: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGAST----QESQFLKID 146
R GA R++ E+KF++RDC+S+P V G+CKETFNLYY E+D D T E+ ++K+D
Sbjct: 80 RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
Query: 147 TIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPA 206
TIAADESF+ DLG R +K+NTEVRS GP+S+ GFYLAFQD G C++++++R++Y+KCP
Sbjct: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
Query: 207 MVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKCVCSAG 265
+++N A F E ++GA+S+SLV RG C+ ++EE D P K+YC+ +GEWLVPIG+C+C AG
Sbjct: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
Query: 266 YE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323
+E E C C G +K+ GD+ C CP +S + + A C C YYRA LDP
Sbjct: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
Query: 324 ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383
CT PSAP +ISSVN TS+ LEW PP D GGR D+ YN +C+ C C CG
Sbjct: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
Query: 384 RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQV 443
++ P+Q L + + +++LLAH Y+F I+AVNGV+D SP + A VNITTNQAAPS V
Sbjct: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
Query: 444 VVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLK 503
++ Q S++L W +P+QPNG+IL+YE++YYEK+ + + +K+ T TV GLK
Sbjct: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
Query: 504 PGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITG---------L 554
G YVFQVRART AG GR+S M +T + +T + L LI G +
Sbjct: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQT---MTEAEYQTSIQEKLPLIIGSSAAGLVFLI 556
Query: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
V+++ ++C +R G+ +A + ++ HY +G H PG + Y +P
Sbjct: 557 AVVVIAIVCNRRR-GFERADSEYTDKLQHYTSG----------HMTPGM----KIYIDPF 601
Query: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
TYE+P A R F +EI+ S + IE++IG+G+ GEVC G L++PG+R++ VAIK LK+GYT
Sbjct: 602 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 661
Query: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
E+QRRDFLSEASIMGQFDHPN+I LEGVVT+ MI+TE+MENGSLD+FLR +DGQFT+
Sbjct: 662 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 721
Query: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD-PDAAY 793
+QLVGMLRG+ AGM+YL+D+ YVHRDLAARN+LV+SNLVCKVSDFGLSR LEDD D Y
Sbjct: 722 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 781
Query: 794 TTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE 852
T+ GGKIPIRWTAPEAI +R F+SASDVWS+G+VMWEV++YGERPYW+MTN+DVI+++E
Sbjct: 782 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 841
Query: 853 EGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSR-C 911
+ YRLP PM CP ALHQLMLDCW KDR RP+F QIV+ LD +IR+P SL+A A +S
Sbjct: 842 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 901
Query: 912 PPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVR 971
P R+ D + TV +WL++I+MG+Y++ FA G++S +V +M +D+
Sbjct: 902 NLPLLDRTIPDYTSFN------TVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDIL 955
Query: 972 ALGITLMGHQKKILGSIQTMRAQLTSTQ 999
+G+TL GHQKKIL SIQ MRAQ+ Q
Sbjct: 956 RVGVTLAGHQKKILNSIQVMRAQMNQIQ 983
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 1033 bits (2671), Expect = 0.0
Identities = 509/988 (51%), Positives = 689/988 (69%), Gaps = 44/988 (4%)
Query: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
E L+D++T + GW+ +P GW+ ++ DE+ I TYQVCNV +QNNWLRT ++
Sbjct: 20 EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
Query: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGAST----QESQFLKID 146
R GA R++ E+KF++RDC+S+P V G+CKETFNLYY E+D D T E+ ++K+D
Sbjct: 80 RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
Query: 147 TIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPA 206
TIAADESF+ DLG R +K+NTEVRS GP+S+ GFYLAFQD G C++++++R++Y+KCP
Sbjct: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
Query: 207 MVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKCVCSAG 265
+++N A F E ++GA+S+SLV RG C+ ++EE D P K+YC+ +GEWLVPIG+C+C AG
Sbjct: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
Query: 266 YE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323
+E E C C G +K+ GD+ C CP +S + + A C C YYRA LDP
Sbjct: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
Query: 324 ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383
CT PSAP +ISSVN TS+ LEW PP D GGR D+ YN +C+ C C CG
Sbjct: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
Query: 384 RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQV 443
++ P+Q L + + +++LLAH Y+F I+AVNGV+D SP + A VNITTNQAAPS V
Sbjct: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
Query: 444 VVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLK 503
++ Q S++L W +P+QPNG+IL+YE++YYEK+ + + +K+ T TV GLK
Sbjct: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
Query: 504 PGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITG---------L 554
G YVFQVRART AG GR+S M +T + +T + L LI G +
Sbjct: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQT---MTEAEYQTSIQEKLPLIIGSSAAGLVFLI 556
Query: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
V+++ ++C +R G+ +A + ++ HY +G H PG + Y +P
Sbjct: 557 AVVVIAIVCNRR--GFERADSEYTDKLQHYTSG----------HMTPGM----KIYIDPF 600
Query: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
TYE+P A R F +EI+ S + IE++IG+G+ GEVC G L++PG+R++ VAIK LK+GYT
Sbjct: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660
Query: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
E+QRRDFLSEASIMGQFDHPN+I LEGVVT+ MI+TE+MENGSLD+FLR +DGQFT+
Sbjct: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720
Query: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD-PDAAY 793
+QLVGMLRG+ AGM+YL+D+ YVHRDLAARN+LV+SNLVCKVSDFGLSR LEDD D Y
Sbjct: 721 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 780
Query: 794 TTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE 852
T+ GGKIPIRWTAPEAI +R F+SASDVWS+G+VMWEV++YGERPYW+MTN+DVI+++E
Sbjct: 781 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 840
Query: 853 EGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSR-C 911
+ YRLP PM CP ALHQLMLDCW KDR RP+F QIV+ LD +IR+P SL+A A +S
Sbjct: 841 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 900
Query: 912 PPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVR 971
P R+ D + TV +WL++I+MG+Y++ FA G++S +V +M +D+
Sbjct: 901 NLPLLDRTIPDYTSFN------TVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDIL 954
Query: 972 ALGITLMGHQKKILGSIQTMRAQLTSTQ 999
+G+TL GHQKKIL SIQ MRAQ+ Q
Sbjct: 955 RVGVTLAGHQKKILNSIQVMRAQMNQIQ 982
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 991 bits (2562), Expect = 0.0
Identities = 514/1020 (50%), Positives = 688/1020 (67%), Gaps = 60/1020 (5%)
Query: 2 APARGRLP--PALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINE 59
+P G LP P L ++ A C + E L+DT + + W ++P GW+ ++
Sbjct: 11 SPPPGLLPLLPPLLLLPLLLLPAGCRAL---EETLMDTKWVTSELAWTSHPESGWEEVSG 67
Query: 60 VDESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCK 119
DE+ PI TYQVCNV +QNNWLRT ++ R +RVY E+KFT+RDCNS+P + G+CK
Sbjct: 68 YDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCK 127
Query: 120 ETFNLYYLESDRDLGASTQ----ESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGP 175
ETFNL+Y E+D D+ +++ E+ ++K+DTIA DESF+ D G ++NT+VRS GP
Sbjct: 128 ETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGP 183
Query: 176 LSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVR 235
LSK GFYLAFQD GAC++++S+R +YKKC + A F E +TGA+ +SLV G C+
Sbjct: 184 LSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIP 243
Query: 236 HSEERDTP-KMYCSAEGEWLVPIGKCVCSAGYEE--RRDACVACELGFYKSAPGDQLCAR 292
++ E P K+YC+ +GEW+VP+G C C+ G+E + C C G YK+ G+ C
Sbjct: 244 NAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLP 303
Query: 293 CPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPL 352
CPP+S + +PAA C C ++YRA D SACT PS P +IS+VN TS+ LEW+ P
Sbjct: 304 CPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPR 363
Query: 353 DPGGRSDITYNAVCRRCPWA--LSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSF 410
D GGR D+ YN +C++C A S C C FVP+Q L + + +++LLAH Y+F
Sbjct: 364 DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423
Query: 411 WIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGII 470
++AVNGVS SP P R A VNITTNQAAPS+V +R + +S++L W PE+PNG+I
Sbjct: 424 EVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVI 483
Query: 471 LEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVE 530
L+YE+KY+EK + + S T+ + + GL+P RYV QVRART AG G++S+ E E
Sbjct: 484 LDYEMKYFEKSEGIAS--TVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFE 541
Query: 531 T------GKPRPRYDTRTIVWIC---LTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEK 581
T G + + IV L + +VV+ ++ + K+RH SD E
Sbjct: 542 TTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRH--------GSDSEY 593
Query: 582 MHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKII 641
L + PG + Y +P TYE+P A R F +EI+ S + IE++I
Sbjct: 594 TEK----------LQQYIAPGM----KVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVI 639
Query: 642 GSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEG 701
G+G+ GEVC GRL+ PG+R+V VAIK LK GYTERQRRDFLSEASIMGQFDHPNIIRLEG
Sbjct: 640 GAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEG 699
Query: 702 VVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDL 761
VVT+ R MI+TE+MEN +LD+FLR +DGQFT++QLVGMLRG+ AGM+YLS++ YVHRDL
Sbjct: 700 VVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDL 759
Query: 762 AARNVLVDSNLVCKVSDFGLSRVLEDDP-DAAYTTT-GGKIPIRWTAPEAIAFRTFSSAS 819
AARN+LV+SNLVCKVSDFGLSR LEDDP D YT++ GGKIPIRWTAPEAIA+R F+SAS
Sbjct: 760 AARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSAS 819
Query: 820 DVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDR 879
DVWS+G+VMWEV++YGERPYW+M+N+DVI++VE+ YRLP PM CP ALHQLMLDCW +DR
Sbjct: 820 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDR 879
Query: 880 AQRPRFSQIVSVLDALIRSPESLRATATV-SRCPPPAFVRSCFDLRGGSGGGGGLTVGDW 938
RP+FSQIV+ LD LIR+ SL+ A+ S P R+ D + TVGDW
Sbjct: 880 NLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFT------TVGDW 933
Query: 939 LDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTST 998
LD+I+MGRY++ F + G++S +V +M A+D+ +G+TL GHQKKIL SIQ MR Q+ T
Sbjct: 934 LDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQT 993
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 911 bits (2354), Expect = 0.0
Identities = 469/995 (47%), Positives = 641/995 (64%), Gaps = 37/995 (3%)
Query: 12 LWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYP-AHGWDSINEVDESFQPIHTY 70
LW AAAAA A EV LLD + G+ GWLT+P GWD + + PI+ Y
Sbjct: 13 LWGCALAAAAA----AQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMY 67
Query: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
VCNVMS +Q+NWLRT+WV R A R++ E+KFT+RDCNS PG +CKETFNLYY ESD
Sbjct: 68 SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESD 127
Query: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
D G + Q+ F KIDTIA DE +D R +KLN E RSVGPL+++GFYLAFQDIGA
Sbjct: 128 LDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA 187
Query: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHS---EERDTPKMYC 247
C+A+LS+R+YYKKCP +++ LA F E + G+D+ SL V G CV H+ + P+M+C
Sbjct: 188 CVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHC 247
Query: 248 SAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQAC 307
+ +GEWLVPIG+C+C AGYE+ DAC AC GF+K + C CP H+ + A +C
Sbjct: 248 AVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307
Query: 308 HCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCR 367
C+ ++RA DP S CTRPPSAP L + G V L W PP D GGR DI Y+ C
Sbjct: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367
Query: 368 RCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRR 427
+C C C + R+ L + S+ V++L HMNY+F +EA NGVS L R
Sbjct: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RS 426
Query: 428 AAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSY 487
+++ NQ P +V R E TS+S+ W P + +YE+ Y +K + SY
Sbjct: 427 FRTASVSINQTEPPKV---RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKG-DSNSY 482
Query: 488 STLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWIC 547
+ + T+ L P T Y+ QV+A T G G S+ E +T P + I +
Sbjct: 483 NVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVA 542
Query: 548 LTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEP 607
+ ++ LV+ + +R + + + Q+P V+ +L
Sbjct: 543 VGVVLLLVLAGVGFFIHRR--------------RKNQRARQSPEDVYFSKSE---QLKPL 585
Query: 608 QFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVP-GQRDVPVAI 666
+ Y +PHTYE+P +A FT EI S + +K+IG+G+ GEV G L+ G+++VPVAI
Sbjct: 586 KTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAI 645
Query: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
K LKAGYTE+QR DFL EA IMGQF H NIIRLEGV+++ + MI+TEYMENG+LD FLR
Sbjct: 646 KTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLR 705
Query: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
DG+F+++QLVGMLRG+ AGM+YL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSRVLE
Sbjct: 706 EKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLE 765
Query: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
DDP+A YTT+GGKIPIRWTAPEAI++R F+SASDVWSFG+VMWEV+ YGERPYW ++N +
Sbjct: 766 DDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHE 825
Query: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
V+ ++ +G+RLP PM CP A++QLM+ CW ++RA+RP+F+ IVS+LD LIR+P+SL+
Sbjct: 826 VMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLK--- 882
Query: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
T++ P +R GS G TV +WL+SI+M +Y +HF A GY+++ V++M
Sbjct: 883 TLADFDPRVSIR--LPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMT 940
Query: 967 AQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
D++ +G+ L GHQK+I S+ ++ Q+ + P
Sbjct: 941 NDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIP 975
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 908 bits (2347), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV 60
MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
Sbjct: 1 MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV 60
Query: 61 DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE 120
DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
Sbjct: 61 DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE 120
Query: 121 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG 180
TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
Sbjct: 121 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG 180
Query: 181 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER 240
FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
Sbjct: 181 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER 240
Query: 241 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA 300
DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
Sbjct: 241 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA 300
Query: 301 APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI 360
APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
Sbjct: 301 APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI 360
Query: 361 TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD 420
TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
Sbjct: 361 TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD 420
Query: 421 LSPEPRRAAVVNITTNQA 438
LSPEPRRAAVVNITTNQA
Sbjct: 421 LSPEPRRAAVVNITTNQA 438
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 869 bits (2246), Expect = 0.0
Identities = 454/994 (45%), Positives = 631/994 (63%), Gaps = 49/994 (4%)
Query: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
EV LLD+ + GW P++GW+ I+ VDE +PI TYQVCNV+ PNQ+NWL+T W+
Sbjct: 35 EVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWIS 94
Query: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQE---SQFLKIDT 147
R +R++ E++FTLRDC+S+PG GTCKETFN+YYLE++ DLG S+ KIDT
Sbjct: 95 RGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDT 154
Query: 148 IAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAM 207
IAADESFT DLG R++KLNTEVR +GPLS+RGF+LAFQD+GAC+A++S+R+YYK+C A
Sbjct: 155 IAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRAT 214
Query: 208 VRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIGKCVCSAG 265
VR LA F + S+LVEV G CV HSE P+M+C A+GEWLVP+G+C CSAG
Sbjct: 215 VRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAG 274
Query: 266 YEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSAC 325
++ER D C AC GFYK +P LC+ CP HS + A+ C C SY R+ DPPS++C
Sbjct: 275 FQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASC 334
Query: 326 TRPPSAPVNLISSVNGTSVTLE--WAPPLDPGGRSDITYNAVCRRC--PWALSRCEACGS 381
TRPPSAP +L S++ + + L W PP D GGRSD+TY+ +C RC CE CG
Sbjct: 335 TRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGP 394
Query: 382 GTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRA-AVVNITTNQAAP 440
F+P+Q L + + + +L Y+ + A+NGVS + A V ++T AP
Sbjct: 395 RVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAP 454
Query: 441 SQVVVIRQERAGQTSVSLLWQEP---EQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRA 497
+ IR++R SVSL W+EP P EYEI+YYEK + Q+YS +K
Sbjct: 455 WEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTV 514
Query: 498 TVSGLKPGTRYVFQVRART---SAGCGRFSQAMEVET-------GKPRPRYDTRTIVWIC 547
TV+ LKP TRYVFQ+RA + S F+ ++EV+T + + T+V I
Sbjct: 515 TVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTIS 574
Query: 548 LTLITGLVVLLLLLICKKRHCGYSKAFQDS-DEEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
L+ G V+ +L + +R C Y K D+ DEE++++ K+P
Sbjct: 575 ALLVLGSVMSVLAIW--RRPCSYGKGGGDAHDEEELYFHF----------------KVPT 616
Query: 607 PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
+ + +P + + +A F +E++A + +E+ +G G GE+C G L++PG++++ VA+
Sbjct: 617 RRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAV 676
Query: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
L+ ++ QR FL+EA +GQFDH +I+RLEGVVTRG MIVTEYM +G+LD FLR
Sbjct: 677 HMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLR 736
Query: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
H+GQ QL+G+L G+ + M+YLS++GYVHR LAAR+VLV S+LVCK+S FG R
Sbjct: 737 RHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPR 794
Query: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
D +A YTT G+ P W APE + F FSSASDVWSFG++MWEV+A+GERPYW+M+ +D
Sbjct: 795 DRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQD 854
Query: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
VI +VE+G+RLP P CP+ LH+LMLDCW KD +RPRFSQI S+L +++ PE +
Sbjct: 855 VIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCAL 914
Query: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
T PP F G +VG WL+++ + RY+D FAA GY SL V M
Sbjct: 915 TTCPRPPTPLADRAFSTFPSFG-----SVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMT 969
Query: 967 AQDVRALGITLMGHQKKILGSIQTMRAQLTSTQG 1000
AQD+ +LGI+L H++ +L I ++A++ QG
Sbjct: 970 AQDLVSLGISLAEHREALLSGISALQARVLQLQG 1003
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 850 bits (2197), Expect = 0.0
Identities = 457/988 (46%), Positives = 624/988 (63%), Gaps = 49/988 (4%)
Query: 27 AARGEVNLLDTSTIHGDWGWLTYPAHG--WDSINEVDESFQPIHTYQVCNVM-SPNQNNW 83
AA E LL+T D W+T+P W+ ++ +DE + TY+VC+V +P Q +W
Sbjct: 13 AAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHW 72
Query: 84 LRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRD----LGASTQE 139
LRT WVPR GA VYA ++FT+ +C S+P +CKETF ++Y ESD D L + E
Sbjct: 73 LRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWME 132
Query: 140 SQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRI 199
+ ++K+DT+AA+ K+N + +GPLSK GFYLAFQD GAC+A+LSL +
Sbjct: 133 NPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHL 192
Query: 200 YYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERD--TPKMYCSAEGEWLV-P 256
+YKKC + NL F E V +V V G CV + +P +YC +G+W P
Sbjct: 193 FYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQP 249
Query: 257 IGKCVCSAGYE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYY 314
+ C C+ G+E E C AC G +K G+ C CP +SHS + C C + Y+
Sbjct: 250 VTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYF 309
Query: 315 RAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALS 374
RA DP + CT PPSAP +++S +NG+S+ LEW+ PL+ GGR D+TY CR C S
Sbjct: 310 RARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGS 369
Query: 375 RCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNIT 434
C CG F P LV+ ++V L Y+F + A+NGVS L+ P VN+T
Sbjct: 370 -CAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVT 428
Query: 435 TNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKE-MQSYSTLKAV 493
T++ P V IR R+ +S+SL W P P+G +L+YE+KY+EK E S LK
Sbjct: 429 TDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTS 488
Query: 494 TTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITG 553
RA + GLK G Y+ QVRAR+ AG G F Q +T + I T + G
Sbjct: 489 ENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLALIAGTAVVG 548
Query: 554 LVVLLLLLIC-----KKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQ 608
+V++L++++ +K+ G + D ++GQ +L H +
Sbjct: 549 VVLVLVVIVVAVLCLRKQSNGREAEYSD--------KHGQ-----YLIGHGT-------K 588
Query: 609 FYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKA 668
Y +P TYE+P A R F +EI+ S + IE++IG+G+ GEVC GRL+ PG+++ VAIK
Sbjct: 589 VYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKT 648
Query: 669 LKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTH 728
LK GYTERQRR+FLSEASIMGQF+HPNIIRLEGVVT MI+TE+MENG+LD+FLR +
Sbjct: 649 LKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLN 708
Query: 729 DGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD 788
DGQFT++QLVGMLRG+ +GMRYL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSR LE++
Sbjct: 709 DGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEEN 768
Query: 789 -PDAAYTTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
D YT++ GGKIPIRWTAPEAIAFR F+SASD WS+G+VMWEV+++GERPYW+M+N+D
Sbjct: 769 SSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQD 828
Query: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
VI+++E+ YRLP P CP +LHQLMLDCW KDR RPRF Q+VS LD +IR+P SL+ A
Sbjct: 829 VINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVA 888
Query: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
+ D R G +VG+WL +I+MGRY + FAA G+ S +V +++
Sbjct: 889 REN----GGASHPLLDQRQPHYSAFG-SVGEWLRAIKMGRYEESFAAAGFGSFELVSQIS 943
Query: 967 AQDVRALGITLMGHQKKILGSIQTMRAQ 994
A+D+ +G+TL GHQKKIL S+Q M++Q
Sbjct: 944 AEDLLRIGVTLAGHQKKILASVQHMKSQ 971
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 739 bits (1909), Expect = 0.0
Identities = 409/1047 (39%), Positives = 605/1047 (57%), Gaps = 114/1047 (10%)
Query: 11 ALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
+LWV+ ++ E LLDT+ + GWLTYP GWD ++ +D+ + T+
Sbjct: 19 SLWVLLLVSSVLAL------EEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTF 72
Query: 71 QVCNVMSP----NQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYY 126
+ C+V Q+NWL+T +V R GA+R + + F++R C+S+ GTC+ETF LYY
Sbjct: 73 EACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYY 132
Query: 127 LESDR----DLGASTQESQFLKIDTIAADESFTGAD-----------------LGVRR-L 164
+++ D +S ++ K+DTIAADESF + G R L
Sbjct: 133 RQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGL 192
Query: 165 KLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEA-VTGADS 223
+LN + RS GPL++RGFY+AFQD GACLA++++R++ CPA++R+ A+F E +GA
Sbjct: 193 QLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGG 252
Query: 224 SSLVEVRGQCVRHSEERDT----------PKMYCSAEGEWLVPIGKCVCSAGYEERRD-- 271
+SLV G CV H+E + P+++C+ EG+W+V +G C C GY+ R
Sbjct: 253 ASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDK 312
Query: 272 ACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSA 331
AC AC G YKS+ G+ C+ CP SH+ PAA C C +YRA+ DPP + CT PPSA
Sbjct: 313 ACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSA 372
Query: 332 PVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALS-------RCEACGSGTR 384
P L V G+++ L W P + GGR D+ +N VC+ C C C
Sbjct: 373 PQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVH 432
Query: 385 FVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVV 444
F P+Q L ++ +LV L AH+ Y ++AVNGVS+LSP+P +AA +N++T+ PS V
Sbjct: 433 FDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVP 492
Query: 445 VIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKP 504
V+ Q S+++ W +P+Q NG IL+Y+++YY++ ++ TL + T ATV+ L P
Sbjct: 493 VVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSP 552
Query: 505 GTRYVFQVRARTSAGCGRFSQAMEVET---GKPRPRYDTRTIVWI-------CLTLITGL 554
G Y FQVRART+AG G + + +T G+ + R + I L+ +
Sbjct: 553 GHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAI 612
Query: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
VL ++ K+R GY++ Q + PG ++Y +P
Sbjct: 613 TVLAVVFQRKRRGTGYTEQLQQ---------------------YSSPGL--GVKYYIDPS 649
Query: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
TYE+P +A R RE++ + I IE++IG+G GEV GRL+ G+R+ VAI+AL AG
Sbjct: 650 TYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGA 709
Query: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
E + FL A+++GQF HPNI+RLEGVVT+ R M++TE+ME G LD+FLR +GQF+
Sbjct: 710 ESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSS 769
Query: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYT 794
+QLV M RGV A M+YLS +VHR L+A +VLV+S+LVCKV+ G ++
Sbjct: 770 LQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG------------HS 817
Query: 795 TTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEG 854
G +RW APE IA +++SDVWSFG++MWEV++YGERPYW+M+ ++V++++E+
Sbjct: 818 PQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQE 877
Query: 855 YRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCP-- 912
+RLP P GCP LH LMLD W KDRA+RP F Q+V+ D +IR P++L+A P
Sbjct: 878 FRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQ 937
Query: 913 ----PPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQ 968
P A C D + WL +I + Y+D+F+ G + V +++ +
Sbjct: 938 ALLTPVALDFPCLD-----------SPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLE 986
Query: 969 DVRALGITLMGHQKKILGSIQTMRAQL 995
D+ ALGITL GHQKK+L IQ ++ L
Sbjct: 987 DLPALGITLAGHQKKLLHHIQLLQQHL 1013
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 726 bits (1875), Expect = 0.0
Identities = 411/983 (41%), Positives = 572/983 (58%), Gaps = 61/983 (6%)
Query: 31 EVNLLDTSTIHGDWGWLTYPAH-GWDSINEVDESFQPIHTYQVCNVMSPNQ-NNWLRTSW 88
EV L+DTS G+ GWL P GW ++ P++ YQ C + ++WLR++W
Sbjct: 27 EVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG-TPLYMYQDCPMQGRRDTDHWLRSNW 85
Query: 89 VPR-DGARRVYAEIKFTLRDCNSMPGVLGT--CKETFNLYYLESDRDLGASTQESQFLKI 145
+ R + A RV+ E++FT+RDC S PG G CKETFNL Y+ESD+D+G + F K+
Sbjct: 86 IYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLFQKV 145
Query: 146 DTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCP 205
T+AAD+SFT DL +KLN E S+G L++RG YLAF + GAC+A++S+R++Y++CP
Sbjct: 146 TTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCP 205
Query: 206 AMVRNLAAFSEAVTGADSSSLVEVRGQCVRHS----EERDTPKMYCSAEGEWLVPIGKCV 261
+ LA F + + G + LVEV G C+ H+ P+M+CS +GEWLVP+G+C
Sbjct: 206 ETLNGLAQFPDTLPG--PAGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCH 263
Query: 262 CSAGYEE--RRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALD 319
C GYEE +ACVAC G Y+ C CP S + + A C C+ +YRA +
Sbjct: 264 CEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRAPGE 323
Query: 320 PPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWAL---SRC 376
P ACT PPSAP NL S +GT ++L W PP D GGR D+ Y+ C +C C
Sbjct: 324 GPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPC 383
Query: 377 EACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTN 436
+ CG G F P L ++ V L + NY+F +EA NGVS L + V+I+
Sbjct: 384 QPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMG 443
Query: 437 QAAPSQVVVIRQERAGQTSVSLLW--QEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVT 494
A + +R + + L W P P G L YE+ +D+E +
Sbjct: 444 HAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYELHVLNQDEERYQ----MVLE 498
Query: 495 TRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT-RTIVWICLTLITG 553
R ++ L+P T Y+ +VR T G G FS E T P R T IV + L+ G
Sbjct: 499 PRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLLG 558
Query: 554 LVVLLLLLICKKRHCGYSKAFQDSD-------EEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
+LL +L+ + R + + D E+K+ +
Sbjct: 559 AALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKP-------------------- 598
Query: 607 PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
Y + YE+P + FTRE++ + + ++ +IG G+ GEV G LR+P Q VAI
Sbjct: 599 ---YVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAI 655
Query: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
K LK Q +FL EA+IMGQF HP+I+ LEGVVT+ + MI+TE+MENG+LD FLR
Sbjct: 656 KTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLR 715
Query: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
+ Q QLV ML+G+ +GM YLS+ YVHRDLAARN+LV+ NL CKVSDFGL+R+L
Sbjct: 716 EREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL- 774
Query: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
DD D Y T GGKIPIRWTAPEAIA R F++ASDVWSFG+VMWEVL++G++PY M+N++
Sbjct: 775 DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQE 834
Query: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
V+ S+E+GYRLP P+ CP L++LM +CW DRA+RP F ++ + L+ L+ +P SLR
Sbjct: 835 VMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLR--- 891
Query: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
T++ P +R GS G TV +WL+SIRM RY HF + G ++ VL +
Sbjct: 892 TIANFDPRMTLR--LPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELT 949
Query: 967 AQDVRALGITLMGHQKKILGSIQ 989
A+D+ +GITL GHQK+IL SIQ
Sbjct: 950 AEDLTQMGITLPGHQKRILCSIQ 972
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 662 bits (1707), Expect = 0.0
Identities = 305/501 (60%), Positives = 387/501 (77%), Gaps = 1/501 (0%)
Query: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
EVNLLD+ TI G+ GW++YP+HGW+ I+ VDE + PI TYQVCNVM +QNNWLRT+WVP
Sbjct: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
Query: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAA 150
R+ A+++Y E+KFTLRDCNS+P VLGTCKETFNLYY+ESD D G +E QF KIDTIAA
Sbjct: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAA 148
Query: 151 DESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRN 210
DESFT DLG R LKLNTE+R VGP++K+GFYLAFQD+GAC+A++S+R+Y+KKCP V+N
Sbjct: 149 DESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKN 208
Query: 211 LAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERR 270
LA F + V DS SLVEVRG CV +S+E D P+MYCS EGEWLVPIGKC C+AGYEER
Sbjct: 209 LAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERG 267
Query: 271 DACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPS 330
C AC GFYK+ G+ CA+CPPHS + + C C+ +Y+RA DPPS ACTRPPS
Sbjct: 268 FMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPS 327
Query: 331 APVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQT 390
+P N+IS++N TSV L+W+ PLD GGR D+T+N +C++C W + +CE C RF+P+Q
Sbjct: 328 SPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
Query: 391 SLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQER 450
L ++ V +LLAH NY+F I+AVNGVS+LS PR+ A V+ITTNQAAPS V+ I+++R
Sbjct: 388 GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
Query: 451 AGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVF 510
+ S+SL WQEPE PNGIIL+YE+KYYEK ++ SY+ L+A T T+S LKP T YVF
Sbjct: 448 TSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVF 507
Query: 511 QVRARTSAGCGRFSQAMEVET 531
Q+RART+AG G S+ E ET
Sbjct: 508 QIRARTAAGYGTNSRKFEFET 528
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 306 bits (784), Expect = 6e-83
Identities = 142/253 (56%), Positives = 186/253 (73%), Gaps = 5/253 (1%)
Query: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
EV LLD+ + GW P++GW+ I+ VDE +PI TYQVCNV+ PNQ+NWL+T W+
Sbjct: 35 EVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWIS 94
Query: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQE---SQFLKIDT 147
R +R++ E++FTLRDC+S+PG GTCKETFN+YYLE++ DLG S+ KIDT
Sbjct: 95 RGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDT 154
Query: 148 IAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAM 207
IAADESFT DLG R++KLNTEVR +GPLS+RGF+LAFQD+GAC+A++S+R+YYK+C A
Sbjct: 155 IAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRAT 214
Query: 208 VRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIGKCVCSAG 265
VR LA F + S+LVEV G CV HSE P+M+C A+GEWLVP+G+C CSAG
Sbjct: 215 VRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAG 274
Query: 266 YEERRDACVACEL 278
++ER D C +L
Sbjct: 275 FQERGDFCEGIQL 287
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 217 bits (552), Expect = 5e-56
Identities = 119/296 (40%), Positives = 166/296 (56%), Gaps = 3/296 (1%)
Query: 606 EPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVA 665
E YAE E+ + EI+ RI + + IG G G+V G P + VA
Sbjct: 415 ETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVA 474
Query: 666 IKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFL 725
IK K ++ R FL EA M QFDHP+I++L GV+T + I+ E G L +FL
Sbjct: 475 IKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTLGELRSFL 533
Query: 726 RTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVL 785
+ + L+ + + YL +VHRD+AARNVLV SN K+ DFGLSR +
Sbjct: 534 QVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM 593
Query: 786 EDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNR 845
ED Y + GK+PI+W APE+I FR F+SASDVW FGV MWE+L +G +P+ + N
Sbjct: 594 EDS--TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNN 651
Query: 846 DVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPES 901
DVI +E G RLP P CP L+ LM CW D ++RPRF+++ + L ++ ++
Sbjct: 652 DVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKA 707
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 217 bits (552), Expect = 5e-56
Identities = 119/296 (40%), Positives = 166/296 (56%), Gaps = 3/296 (1%)
Query: 606 EPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVA 665
E YAE E+ + EI+ RI + + IG G G+V G P + VA
Sbjct: 393 ETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVA 452
Query: 666 IKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFL 725
IK K ++ R FL EA M QFDHP+I++L GV+T + I+ E G L +FL
Sbjct: 453 IKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTLGELRSFL 511
Query: 726 RTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVL 785
+ + L+ + + YL +VHRD+AARNVLV SN K+ DFGLSR +
Sbjct: 512 QVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM 571
Query: 786 EDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNR 845
ED Y + GK+PI+W APE+I FR F+SASDVW FGV MWE+L +G +P+ + N
Sbjct: 572 EDS--TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNN 629
Query: 846 DVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPES 901
DVI +E G RLP P CP L+ LM CW D ++RPRF+++ + L ++ ++
Sbjct: 630 DVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKA 685
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 210 bits (535), Expect = 5e-54
Identities = 114/273 (41%), Positives = 161/273 (58%), Gaps = 10/273 (3%)
Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
EI + + K +G+G GEV G + VAIK LK G + FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWN----GNTKVAIKTLKPGTMSPE--SFLEEAQIM 318
Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQ-FTIMQLVGMLRGVGAG 747
+ H +++L VV+ + IVTEYM GSL FL+ +G+ + LV M V AG
Sbjct: 319 KKLKHDKLVQLYAVVSEEPI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M Y+ + Y+HRDL + N+LV + L+CK++DFGL+R++ED+ A G K PI+WTAP
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTA--RQGAKFPIKWTAP 435
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EA + F+ SDVWSFG+++ E++ G PY M NR+V+ VE GYR+P P CP +L
Sbjct: 436 EAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISL 495
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
H+LM+ CW KD +RP F + S L+ + E
Sbjct: 496 HELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 528
>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform B [Homo sapiens]
Length = 491
Score = 210 bits (534), Expect = 6e-54
Identities = 113/273 (41%), Positives = 160/273 (58%), Gaps = 9/273 (3%)
Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
EI I + K +G+G GEV G VA+K LK G Q FL EA++M
Sbjct: 220 EIPRESIKLVKRLGAGQFGEVWMGYYN----NSTKVAVKTLKPGTMSVQA--FLEEANLM 273
Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIM-QLVGMLRGVGAG 747
H ++RL VVTR I+TEYM GSL FL++ +G ++ +L+ + G
Sbjct: 274 KTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEG 333
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M Y+ Y+HRDL A NVLV +L+CK++DFGL+RV+ED+ A G K PI+WTAP
Sbjct: 334 MAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTA--REGAKFPIKWTAP 391
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EAI F F+ SDVWSFG++++E++ YG+ PY TN DV++++ +GYR+P CP L
Sbjct: 392 EAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDEL 451
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
+ +M CW + +RP F + SVLD + E
Sbjct: 452 YDIMKMCWKEKAEERPTFDYLQSVLDDFYTATE 484
>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform A [Homo sapiens]
Length = 512
Score = 210 bits (534), Expect = 6e-54
Identities = 113/273 (41%), Positives = 160/273 (58%), Gaps = 9/273 (3%)
Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
EI I + K +G+G GEV G VA+K LK G Q FL EA++M
Sbjct: 241 EIPRESIKLVKRLGAGQFGEVWMGYYN----NSTKVAVKTLKPGTMSVQA--FLEEANLM 294
Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIM-QLVGMLRGVGAG 747
H ++RL VVTR I+TEYM GSL FL++ +G ++ +L+ + G
Sbjct: 295 KTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEG 354
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M Y+ Y+HRDL A NVLV +L+CK++DFGL+RV+ED+ A G K PI+WTAP
Sbjct: 355 MAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTA--REGAKFPIKWTAP 412
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EAI F F+ SDVWSFG++++E++ YG+ PY TN DV++++ +GYR+P CP L
Sbjct: 413 EAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDEL 472
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
+ +M CW + +RP F + SVLD + E
Sbjct: 473 YDIMKMCWKEKAEERPTFDYLQSVLDDFYTATE 505
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 210 bits (534), Expect = 6e-54
Identities = 115/305 (37%), Positives = 174/305 (57%), Gaps = 10/305 (3%)
Query: 598 HHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVP 657
H+ G Q + P +P + EI + +EK +G+G GEV
Sbjct: 225 HYKKGNDGLCQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYN-- 282
Query: 658 GQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYME 717
+ VA+K +K G + FL+EA++M H +++L VVT+ + I+TE+M
Sbjct: 283 --KHTKVAVKTMKPGSMSVEA--FLAEANVMKTLQHDKLVKLHAVVTKEPI-YIITEFMA 337
Query: 718 NGSLDTFLRTHDG-QFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKV 776
GSL FL++ +G + + +L+ + GM ++ Y+HRDL A N+LV ++LVCK+
Sbjct: 338 KGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKI 397
Query: 777 SDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGE 836
+DFGL+RV+ED+ A G K PI+WTAPEAI F +F+ SDVWSFG+++ E++ YG
Sbjct: 398 ADFGLARVIEDNEYTA--REGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR 455
Query: 837 RPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALI 896
PY M+N +VI ++E GYR+P P CP L+ +M+ CW +RP F I SVLD
Sbjct: 456 IPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFY 515
Query: 897 RSPES 901
+ ES
Sbjct: 516 TATES 520
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 210 bits (534), Expect = 6e-54
Identities = 118/273 (43%), Positives = 158/273 (57%), Gaps = 10/273 (3%)
Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
EI + +E +G G GEV G VAIK LK G + FL EA IM
Sbjct: 271 EIPRESLRLEVKLGQGCFGEVWMGTWN----GTTKVAIKTLKPGTMMPEA--FLQEAQIM 324
Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFT-IMQLVGMLRGVGAG 747
+ H ++ L VV+ + IVTE+M GSL FL+ DG++ + QLV M + G
Sbjct: 325 KKLRHDKLVPLYAVVSEEPI-YIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADG 383
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M Y+ + Y+HRDL A N+LV NLVCK++DFGL+R++ED+ A G K PI+WTAP
Sbjct: 384 MAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTA--RQGAKFPIKWTAP 441
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EA + F+ SDVWSFG++ E++ G PY M NR+V+ VE GYR+P P GCP +L
Sbjct: 442 EAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESL 501
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
H+LM CW KD +RP F I S L+ + E
Sbjct: 502 HELMNLCWKKDPDERPTFEYIQSFLEDYFTATE 534
>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 209 bits (532), Expect = 1e-53
Identities = 114/273 (41%), Positives = 164/273 (60%), Gaps = 10/273 (3%)
Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
E+ + + + +G+G GEV G VA+K+LK G FL+EA++M
Sbjct: 239 EVPRETLKLVERLGAGQFGEVWMGYYN----GHTKVAVKSLKQGSMSPDA--FLAEANLM 292
Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDG-QFTIMQLVGMLRGVGAG 747
Q H ++RL VVT+ + I+TEYMENGSL FL+T G + TI +L+ M + G
Sbjct: 293 KQLQHQRLVRLYAVVTQEPI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M ++ + Y+HRDL A N+LV L CK++DFGL+R++ED+ A G K PI+WTAP
Sbjct: 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTA--REGAKFPIKWTAP 409
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EAI + TF+ SDVWSFG+++ E++ +G PY MTN +VI ++E GYR+ P CP L
Sbjct: 410 EAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEEL 469
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
+QLM CW + RP F + SVL+ + E
Sbjct: 470 YQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 502
>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 209 bits (532), Expect = 1e-53
Identities = 114/273 (41%), Positives = 164/273 (60%), Gaps = 10/273 (3%)
Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
E+ + + + +G+G GEV G VA+K+LK G FL+EA++M
Sbjct: 239 EVPRETLKLVERLGAGQFGEVWMGYYN----GHTKVAVKSLKQGSMSPDA--FLAEANLM 292
Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDG-QFTIMQLVGMLRGVGAG 747
Q H ++RL VVT+ + I+TEYMENGSL FL+T G + TI +L+ M + G
Sbjct: 293 KQLQHQRLVRLYAVVTQEPI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M ++ + Y+HRDL A N+LV L CK++DFGL+R++ED+ A G K PI+WTAP
Sbjct: 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTA--REGAKFPIKWTAP 409
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EAI + TF+ SDVWSFG+++ E++ +G PY MTN +VI ++E GYR+ P CP L
Sbjct: 410 EAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEEL 469
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
+QLM CW + RP F + SVL+ + E
Sbjct: 470 YQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 502
>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 208 bits (529), Expect = 2e-53
Identities = 116/273 (42%), Positives = 158/273 (57%), Gaps = 10/273 (3%)
Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
EI + +E +G G GEV G + VAIK LK G + FL EA +M
Sbjct: 264 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTMSPEA--FLQEAQVM 317
Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFT-IMQLVGMLRGVGAG 747
+ H +++L VV+ + IVTEYM GSL FL+ G++ + QLV M + +G
Sbjct: 318 KKLRHEKLVQLYAVVSEEPI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASG 376
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M Y+ + YVHRDL A N+LV NLVCKV+DFGL+R++ED+ A G K PI+WTAP
Sbjct: 377 MAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA--RQGAKFPIKWTAP 434
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EA + F+ SDVWSFG+++ E+ G PY M NR+V+ VE GYR+P P CP +L
Sbjct: 435 EAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESL 494
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
H LM CW K+ +RP F + + L+ S E
Sbjct: 495 HDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTE 527
>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 208 bits (529), Expect = 2e-53
Identities = 116/273 (42%), Positives = 158/273 (57%), Gaps = 10/273 (3%)
Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
EI + +E +G G GEV G + VAIK LK G + FL EA +M
Sbjct: 264 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTMSPEA--FLQEAQVM 317
Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFT-IMQLVGMLRGVGAG 747
+ H +++L VV+ + IVTEYM GSL FL+ G++ + QLV M + +G
Sbjct: 318 KKLRHEKLVQLYAVVSEEPI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASG 376
Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
M Y+ + YVHRDL A N+LV NLVCKV+DFGL+R++ED+ A G K PI+WTAP
Sbjct: 377 MAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA--RQGAKFPIKWTAP 434
Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
EA + F+ SDVWSFG+++ E+ G PY M NR+V+ VE GYR+P P CP +L
Sbjct: 435 EAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESL 494
Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
H LM CW K+ +RP F + + L+ S E
Sbjct: 495 HDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTE 527
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,728,260
Number of Sequences: 37866
Number of extensions: 2029570
Number of successful extensions: 10480
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 620
Number of HSP's successfully gapped in prelim test: 328
Number of HSP's that attempted gapping in prelim test: 6706
Number of HSP's gapped (non-prelim): 2215
length of query: 1005
length of database: 18,247,518
effective HSP length: 112
effective length of query: 893
effective length of database: 14,006,526
effective search space: 12507827718
effective search space used: 12507827718
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.