Guide to the Human Genome
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Search of human proteins with 10140845

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
         (1005 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi...  2057   0.0  
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...  1221   0.0  
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...  1212   0.0  
gi|4758282 ephrin receptor EphA7 [Homo sapiens]                      1189   0.0  
gi|4758280 ephrin receptor EphA4 [Homo sapiens]                      1170   0.0  
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi...  1169   0.0  
gi|145312251 EPH receptor A6 isoform a [Homo sapiens]                1147   0.0  
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]            1039   0.0  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...  1033   0.0  
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...  1033   0.0  
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]            991   0.0  
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                      911   0.0  
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi...   908   0.0  
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]                 869   0.0  
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                  850   0.0  
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]           739   0.0  
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                     726   0.0  
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi...   662   0.0  
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]                306   6e-83
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]   217   5e-56
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]   217   5e-56
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]       210   5e-54
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...   210   6e-54
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...   210   6e-54
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]     210   6e-54
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]              210   6e-54
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs...   209   1e-53
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs...   209   1e-53
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...   208   2e-53
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...   208   2e-53

>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
          Length = 1005

 Score = 2057 bits (5329), Expect = 0.0
 Identities = 1005/1005 (100%), Positives = 1005/1005 (100%)

Query: 1    MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV 60
            MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
Sbjct: 1    MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV 60

Query: 61   DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE 120
            DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
Sbjct: 61   DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE 120

Query: 121  TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG 180
            TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
Sbjct: 121  TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG 180

Query: 181  FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER 240
            FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
Sbjct: 181  FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER 240

Query: 241  DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA 300
            DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
Sbjct: 241  DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA 300

Query: 301  APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI 360
            APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
Sbjct: 301  APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI 360

Query: 361  TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD 420
            TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
Sbjct: 361  TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD 420

Query: 421  LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK 480
            LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK
Sbjct: 421  LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK 480

Query: 481  DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT 540
            DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT
Sbjct: 481  DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT 540

Query: 541  RTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHP 600
            RTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHP
Sbjct: 541  RTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHP 600

Query: 601  PGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR 660
            PGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR
Sbjct: 601  PGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR 660

Query: 661  DVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGS 720
            DVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGS
Sbjct: 661  DVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGS 720

Query: 721  LDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFG 780
            LDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFG
Sbjct: 721  LDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFG 780

Query: 781  LSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW 840
            LSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW
Sbjct: 781  LSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW 840

Query: 841  NMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
            NMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE
Sbjct: 841  NMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900

Query: 901  SLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLG 960
            SLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLG
Sbjct: 901  SLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLG 960

Query: 961  MVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL 1005
            MVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL
Sbjct: 961  MVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL 1005


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
          Length = 1015

 Score = 1221 bits (3159), Expect = 0.0
 Identities = 586/994 (58%), Positives = 746/994 (75%), Gaps = 23/994 (2%)

Query: 12   LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
            LW  +   AA  T +++   EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 40   LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99

Query: 71   QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
            QVC VM  NQNNWL TSW+  +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 100  QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159

Query: 131  RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
               G + +E+Q++KIDTIAADESFT  DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 160  DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219

Query: 191  CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250
            C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS   + PKM+CSAE
Sbjct: 220  CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279

Query: 251  GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310
            GEWLVPIGKC+C AGYEE+   C  C  GF+K++P  Q C +CPPHS++   A+ +C C+
Sbjct: 280  GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339

Query: 311  LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370
              Y+R   DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y   C++C 
Sbjct: 340  KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399

Query: 371  WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
                 CE CG   R++P+Q+ L   S+++ +LLAH NY+F IEAVNGVSDLSP  R+   
Sbjct: 400  SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459

Query: 431  VNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTL 490
            VN+TTNQAAPS V  +++ +  + S+SL WQEP++PNGIILEYEIKY+EKD+E  SY+ +
Sbjct: 460  VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTII 518

Query: 491  KAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKP-RPRYDTRTIVWICLT 549
            K+  T  T  GLKP + YVFQ+RART+AG G FS+  E ET        D   I  I ++
Sbjct: 519  KSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVS 578

Query: 550  LITGLVVLLLLL--ICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEP 607
            +  G+++L +++  +   R CGYSKA QD +EEKMH+ NG               KLP  
Sbjct: 579  VTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHI-------------KLPGV 625

Query: 608  QFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIK 667
            + Y +PHTYE+P +A   F +EIEAS I IE++IG+G+ GEVC GRL++PG+R++PVAIK
Sbjct: 626  RTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIK 685

Query: 668  ALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRT 727
             LK GYTE+QRRDFL EASIMGQFDHPNII LEGVVT+ +  MIVTEYMENGSLDTFL+ 
Sbjct: 686  TLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKK 745

Query: 728  HDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLED 787
            +DGQFT++QLVGMLRG+ AGM+YLSD+GYVHRDLAARN+L++SNLVCKVSDFGLSRVLED
Sbjct: 746  NDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLED 805

Query: 788  DPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDV 847
            DP+AAYTT GGKIPIRWTAPEAIAFR F+SASDVWS+G+VMWEV++YGERPYW MTN+DV
Sbjct: 806  DPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDV 865

Query: 848  ISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATAT 907
            I +VEEGYRLP+PM CP AL+QLMLDCW K+R  RP+F +IV++LD LIR+P SL+    
Sbjct: 866  IKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVN 925

Query: 908  VSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNA 967
             S       V +        G G   +VG+WL++I+MGRY + F   GYSS+  V ++  
Sbjct: 926  AS-----CRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 980

Query: 968  QDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
            +D+R LG+TL+GHQKKI+ S+Q M+ QL +   P
Sbjct: 981  EDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVP 1014


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
          Length = 1037

 Score = 1212 bits (3137), Expect = 0.0
 Identities = 587/1016 (57%), Positives = 747/1016 (73%), Gaps = 45/1016 (4%)

Query: 12   LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
            LW  +   AA  T +++   EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 40   LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99

Query: 71   QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
            QVC VM  NQNNWL TSW+  +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 100  QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159

Query: 131  RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
               G + +E+Q++KIDTIAADESFT  DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 160  DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219

Query: 191  CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250
            C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS   + PKM+CSAE
Sbjct: 220  CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279

Query: 251  GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310
            GEWLVPIGKC+C AGYEE+   C  C  GF+K++P  Q C +CPPHS++   A+ +C C+
Sbjct: 280  GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339

Query: 311  LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370
              Y+R   DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y   C++C 
Sbjct: 340  KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399

Query: 371  WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
                 CE CG   R++P+Q+ L   S+++ +LLAH NY+F IEAVNGVSDLSP  R+   
Sbjct: 400  SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459

Query: 431  VNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTL 490
            VN+TTNQAAPS V  +++ +  + S+SL WQEP++PNGIILEYEIKY+EKD+E  SY+ +
Sbjct: 460  VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTII 518

Query: 491  KAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKP-RPRYDTRTIVWICLT 549
            K+  T  T  GLKP + YVFQ+RART+AG G FS+  E ET        D   I  I ++
Sbjct: 519  KSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVS 578

Query: 550  LITGLVVLLLLL------------------ICKKRH------CGYSKAFQDSDEEKMHYQ 585
            +  G+++L +++                  +C   H      CGYSKA QD +EEKMH+ 
Sbjct: 579  VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH 638

Query: 586  NGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGD 645
            NG               KLP  + Y +PHTYE+P +A   F +EIEAS I IE++IG+G+
Sbjct: 639  NGHI-------------KLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGE 685

Query: 646  SGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTR 705
             GEVC GRL++PG+R++PVAIK LK GYTE+QRRDFL EASIMGQFDHPNII LEGVVT+
Sbjct: 686  FGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTK 745

Query: 706  GRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARN 765
             +  MIVTEYMENGSLDTFL+ +DGQFT++QLVGMLRG+ AGM+YLSD+GYVHRDLAARN
Sbjct: 746  SKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARN 805

Query: 766  VLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFG 825
            +L++SNLVCKVSDFGLSRVLEDDP+AAYTT GGKIPIRWTAPEAIAFR F+SASDVWS+G
Sbjct: 806  ILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYG 865

Query: 826  VVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRF 885
            +VMWEV++YGERPYW MTN+DVI +VEEGYRLP+PM CP AL+QLMLDCW K+R  RP+F
Sbjct: 866  IVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKF 925

Query: 886  SQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMG 945
             +IV++LD LIR+P SL+     S       V +        G G   +VG+WL++I+MG
Sbjct: 926  DEIVNMLDKLIRNPSSLKTLVNAS-----CRVSNLLAEHSPLGSGAYRSVGEWLEAIKMG 980

Query: 946  RYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
            RY + F   GYSS+  V ++  +D+R LG+TL+GHQKKI+ S+Q M+ QL +   P
Sbjct: 981  RYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVP 1036


>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
          Length = 998

 Score = 1189 bits (3076), Expect = 0.0
 Identities = 577/995 (57%), Positives = 736/995 (73%), Gaps = 38/995 (3%)

Query: 21   AATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQ 80
            A T  + A  EV LLD+     +  W++ P +GW+ I+ +DE++ PI TYQVC VM PNQ
Sbjct: 22   AHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQ 81

Query: 81   NNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQES 140
            NNWLRT+W+ +  A+R++ E+KFTLRDCNS+PGVLGTCKETFNLYY E+D D G + +E+
Sbjct: 82   NNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIREN 141

Query: 141  QFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIY 200
             ++KIDTIAADESFT  DLG R++KLNTEVR +GPLSK+GFYLAFQD+GAC+A++S+++Y
Sbjct: 142  LYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVY 201

Query: 201  YKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIG 258
            YKKC +++ NLA F + VTG++ SSLVEVRG CV  +EE   + P+M+CSAEGEWLVPIG
Sbjct: 202  YKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIG 261

Query: 259  KCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAAL 318
            KC+C AGY+++ D C  C  GFYKS+  D  C+RCP HS S    +  C C+  YYRA  
Sbjct: 262  KCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPS 321

Query: 319  DPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEA 378
            DPP  ACTRPPSAP NLI ++N T+V+LEW+PP D GGR+D+TY  +C+RC W    C  
Sbjct: 322  DPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVP 381

Query: 379  CGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438
            CGS   ++PQQT L    + V +LLAH NY+F +EAVNGVSDLS   R  A V+ITT QA
Sbjct: 382  CGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQA 441

Query: 439  APSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRAT 498
            APSQV  + +ER  Q SV L WQEPE PNG+I EYEIKYYEKD+  ++YST+K  +T A+
Sbjct: 442  APSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSAS 501

Query: 499  VSGLKPGTRYVFQVRARTSAGCGRFSQAMEVET-----GK----PRPRYDTRTIVWICLT 549
            ++ LKPGT YVFQ+RA T+AG G +S  ++V T     GK         +   ++ I + 
Sbjct: 502  INNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVV 561

Query: 550  LITGLVVLLLLL---ICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
             + G ++L+ ++   I  +RHCGYSKA Q+ DEE              L  H    K P 
Sbjct: 562  AVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEE--------------LYFHF---KFPG 604

Query: 607  PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
             + Y +P TYE+P RA   F +E++AS I IE++IG+G+ GEVC GRL++PG+RDV VAI
Sbjct: 605  TKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAI 664

Query: 667  KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
            K LK GYTE+QRRDFL EASIMGQFDHPN++ LEGVVTRG+  MIV E+MENG+LD FLR
Sbjct: 665  KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724

Query: 727  THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
             HDGQFT++QLVGMLRG+ AGMRYL+D+GYVHRDLAARN+LV+SNLVCKVSDFGLSRV+E
Sbjct: 725  KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIE 784

Query: 787  DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
            DDP+A YTTTGGKIP+RWTAPEAI +R F+SASDVWS+G+VMWEV++YGERPYW+M+N+D
Sbjct: 785  DDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 844

Query: 847  VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRA-T 905
            VI ++EEGYRLPAPM CP  LHQLMLDCW K+RA+RP+F QIV +LD +IR+P SL+   
Sbjct: 845  VIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPL 904

Query: 906  ATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRM 965
             T SR   P   ++  D           +VG+WL +I+M RY+D+F A GY+SL  V RM
Sbjct: 905  GTCSRPISPLLDQNTPDFT------TFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARM 958

Query: 966  NAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQG 1000
              +DV +LGITL+GHQKKI+ SIQTMRAQ+    G
Sbjct: 959  TIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHG 993


>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
          Length = 986

 Score = 1170 bits (3027), Expect = 0.0
 Identities = 566/977 (57%), Positives = 722/977 (73%), Gaps = 32/977 (3%)

Query: 31   EVNLLDTSTIHGDWGWLTYPAHG-WDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWV 89
            EV LLD+ ++ G+ GW+  P  G W+ ++ +DE   PI TYQVCNVM P+QNNWLRT W+
Sbjct: 30   EVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWI 89

Query: 90   PRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIA 149
             R+GA+RVY EIKFTLRDCNS+PGV+GTCKETFNLYY ESD D     +E+QF+KIDTIA
Sbjct: 90   TREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIA 149

Query: 150  ADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVR 209
            ADESFT  D+G R +KLNTE+R VGPLSK+GFYLAFQD+GAC+A++S+R++YKKCP  VR
Sbjct: 150  ADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVR 209

Query: 210  NLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEER 269
            NLA F + +TGAD+SSLVEVRG CV +SEE+D PKMYC A+GEWLVPIG C+C+AG+EER
Sbjct: 210  NLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEER 269

Query: 270  RDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPP 329
               C AC++G+YK+   D  CA+CPPHS+S    A +C CD  ++RA  D  S  CTRPP
Sbjct: 270  SGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPP 329

Query: 330  SAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWA-LSRCEACGSGTRFVPQ 388
            SAP+NLIS+VN TSV LEW+ P + GGR DI+YN VC++C     S+C  CGSG  + PQ
Sbjct: 330  SAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQ 389

Query: 389  QTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQ 448
            Q  L    + + +LLAH NY+F I AVNGVS  +P P ++  V +TTNQAAPS + +++ 
Sbjct: 390  QNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIALVQA 449

Query: 449  ERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRY 508
            +   + SV+L W EP++PNG+ILEYE+KYYEKD+  +SY  ++       + GL P T Y
Sbjct: 450  KEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSY 509

Query: 509  VFQVRARTSAGCGRFSQAMEVETGK-PRPRYDTRTIVWICLTLITGLVVLLLLLIC---- 563
            VF VRART+AG G FS+ +EV T   P           + L  ++G VVL+++LI     
Sbjct: 510  VFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVI 569

Query: 564  KKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAG 623
             +R   YSKA Q++DEEK H   G                    + Y +P TYE+P +A 
Sbjct: 570  SRRRSKYSKAKQEADEEK-HLNQGV-------------------RTYVDPFTYEDPNQAV 609

Query: 624  RSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLS 683
            R F +EI+AS I IEK+IG G+ GEVC GRL+VPG+R++ VAIK LKAGYT++QRRDFLS
Sbjct: 610  REFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLS 669

Query: 684  EASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRG 743
            EASIMGQFDHPNII LEGVVT+ +  MI+TEYMENGSLD FLR +DG+FT++QLVGMLRG
Sbjct: 670  EASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRG 729

Query: 744  VGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIR 803
            +G+GM+YLSD+ YVHRDLAARN+LV+SNLVCKVSDFG+SRVLEDDP+AAYTT GGKIPIR
Sbjct: 730  IGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIR 789

Query: 804  WTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGC 863
            WTAPEAIA+R F+SASDVWS+G+VMWEV++YGERPYW+M+N+DVI ++EEGYRLP PM C
Sbjct: 790  WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDC 849

Query: 864  PHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDL 923
            P ALHQLMLDCW K+R+ RP+F QIV++LD LIR+P SL+ T T S  P  A +      
Sbjct: 850  PIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDP---- 905

Query: 924  RGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKK 983
                     ++VGDWL +I+M RY+D+F A GY++L  V+ +N +D+  +GIT + HQ K
Sbjct: 906  -SSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNK 964

Query: 984  ILGSIQTMRAQLTSTQG 1000
            IL S+Q MR Q+    G
Sbjct: 965  ILSSVQAMRTQMQQMHG 981


>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapiens]
          Length = 983

 Score = 1169 bits (3024), Expect = 0.0
 Identities = 558/975 (57%), Positives = 730/975 (74%), Gaps = 27/975 (2%)

Query: 31   EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
            EVNLLD+ TI G+ GW++YP+HGW+ I+ VDE + PI TYQVCNVM  +QNNWLRT+WVP
Sbjct: 29   EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88

Query: 91   RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAA 150
            R+ A+++Y E+KFTLRDCNS+P VLGTCKETFNLYY+ESD D G   +E QF KIDTIAA
Sbjct: 89   RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAA 148

Query: 151  DESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRN 210
            DESFT  DLG R LKLNTE+R VGP++K+GFYLAFQD+GAC+A++S+R+Y+KKCP  V+N
Sbjct: 149  DESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKN 208

Query: 211  LAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERR 270
            LA F + V   DS SLVEVRG CV +S+E D P+MYCS EGEWLVPIGKC C+AGYEER 
Sbjct: 209  LAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERG 267

Query: 271  DACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPS 330
              C AC  GFYK+  G+  CA+CPPHS +    +  C C+ +Y+RA  DPPS ACTRPPS
Sbjct: 268  FMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPS 327

Query: 331  APVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQT 390
            +P N+IS++N TSV L+W+ PLD GGR D+T+N +C++C W + +CE C    RF+P+Q 
Sbjct: 328  SPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387

Query: 391  SLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQER 450
             L   ++ V +LLAH NY+F I+AVNGVS+LS  PR+ A V+ITTNQAAPS V+ I+++R
Sbjct: 388  GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447

Query: 451  AGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVF 510
              + S+SL WQEPE PNGIIL+YE+KYYEK ++  SY+ L+A  T  T+S LKP T YVF
Sbjct: 448  TSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVF 507

Query: 511  QVRARTSAGCGRFSQAMEVETGKPRPRY--DTRTIVWICLTLITGLVVLLLLL-ICKKRH 567
            Q+RART+AG G  S+  E ET         ++  +V I ++    +++L +++ +   R 
Sbjct: 508  QIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVLIGRF 567

Query: 568  CGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFT 627
            CGY K+   +DE+++H+ NG               KLP  + Y +PHTYE+P +A   F 
Sbjct: 568  CGY-KSKHGADEKRLHFGNGHL-------------KLPGLRTYVDPHTYEDPTQAVHEFA 613

Query: 628  REIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASI 687
            +E++A+ I I+K++G+G+ GEVC GRL++P ++++ VAIK LK GYTE+QRRDFL EASI
Sbjct: 614  KELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASI 673

Query: 688  MGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAG 747
            MGQFDHPNIIRLEGVVT+ +  MIVTEYMENGSLD+FLR HD QFT++QLVGMLRG+ +G
Sbjct: 674  MGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASG 733

Query: 748  MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
            M+YLSD+GYVHRDLAARN+L++SNLVCKVSDFGLSRVLEDDP+AAYTT GGKIPIRWT+P
Sbjct: 734  MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSP 793

Query: 808  EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
            EAIA+R F+SASDVWS+G+V+WEV++YGERPYW M+N+DVI +V+EGYRLP PM CP AL
Sbjct: 794  EAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAAL 853

Query: 868  HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFV-RSCFDLRGG 926
            +QLMLDCW KDR  RP+F QIVS+LD LIR+P SL+   + +  P    + +S  D+   
Sbjct: 854  YQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTF 913

Query: 927  SGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILG 986
                   T GDWL+ +     ++ F    YSS   + +++  D++ +G+T++G QKKI+ 
Sbjct: 914  R------TTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIIS 967

Query: 987  SIQTMRAQLTSTQGP 1001
            SI+ +  Q  S  GP
Sbjct: 968  SIKALETQ--SKNGP 980


>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
          Length = 1130

 Score = 1147 bits (2968), Expect = 0.0
 Identities = 557/1039 (53%), Positives = 723/1039 (69%), Gaps = 86/1039 (8%)

Query: 24   CVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNW 83
            C   +  +V LLDT+T+ G+ GW TYP +GWD+I E+DE  +PIHTYQVCNVM PNQNNW
Sbjct: 121  CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW 180

Query: 84   LRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFL 143
            LRT+W+ RD A+++Y E+KFTLRDCNS+P VLGTCKETFNL+Y+ESD   G   + +Q+ 
Sbjct: 181  LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT 240

Query: 144  KIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKK 203
            KIDTIAADESFT  DLG R LKLNTE+R VGP+ ++GFYLAFQDIGAC+A++S+R++YKK
Sbjct: 241  KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK 300

Query: 204  CPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCS 263
            CP  VRNLA F + +   DSSSLVEVRG CV+ +EERDTPK+YC A+G+WLVP+G+C+CS
Sbjct: 301  CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS 360

Query: 264  AGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323
             GYEE   +C AC  GFYK+  G+  C++CPPHS +   A   C C+  Y+RA  DPPS 
Sbjct: 361  TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM 420

Query: 324  ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383
            ACTRPPSAP N++ ++N T++ LEW+PP D GGR D+TY+ +C++C    S+CE CG G 
Sbjct: 421  ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL 480

Query: 384  RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQV 443
            RF+P+ T L+  S++V + ++H+NY+F IEA+NGVS+LS  P+    + +TT+Q APS +
Sbjct: 481  RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI 540

Query: 444  VVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLK 503
             V+R++ A Q S++L WQ P   NG IL+YEIKYYEK+ E  +YS+ ++      ++GLK
Sbjct: 541  GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK 600

Query: 504  PGTRYVFQVRARTSAGCGRFSQAMEVETGKPRP--RYDTRTIVWICLTLITG---LVVLL 558
            P T+YVF +R RT+ G   +SQ  E ETG        +   I+ I    + G   LV+L 
Sbjct: 601  PATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILT 660

Query: 559  LLLICKKRHCGYSKAFQDSDEEKM-HYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYE 617
            L  +   R   Y KA   S+E++  H QNG               + P  + Y +P TYE
Sbjct: 661  LFFLITGRCQWYIKAKMKSEEKRRNHLQNGHL-------------RFPGIKTYIDPDTYE 707

Query: 618  EPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQ 677
            +P  A   F +EI+ SRI IE++IG+G+ GEVC GRL+ PG+R++PVAIK LK G+ +RQ
Sbjct: 708  DPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQ 767

Query: 678  RRDFLSEASIMGQFDHPNIIRLEGVVTR-------------------------------- 705
            RRDFL EASIMGQFDHPNIIRLEGVVT+                                
Sbjct: 768  RRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPG 827

Query: 706  ----------GRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLG 755
                      GR  MIV EYMENGSLD+FLR HDG FT++QLVGMLRG+ +GM+YLSD+G
Sbjct: 828  GGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMG 887

Query: 756  YVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTF 815
            YVHRDLAARN+LV+SNLVCKVSDFGLSRVLEDDP+AAYTTTGGKIPIRWTAPEAIA+R F
Sbjct: 888  YVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKF 947

Query: 816  SSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCW 875
            SSASD WS+G+VMWEV++YGERPYW M+N+DVI S+EEGYRLPAPMGCP +LHQLML CW
Sbjct: 948  SSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCW 1007

Query: 876  HKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPP---------PAFVRSCFDLRGG 926
             K+R  RP+F+ IVS LD LIR+P +L          P         P FV         
Sbjct: 1008 QKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFV--------- 1058

Query: 927  SGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILG 986
                   TVGDWLDSI+MG+Y+++F A G+++  ++ RM+  D+R +G+ L+GHQ++I+ 
Sbjct: 1059 -------TVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVS 1111

Query: 987  SIQTMRAQLTSTQGPRRHL 1005
            SIQT+R  +   Q    H+
Sbjct: 1112 SIQTLRLHMMHIQEKGFHV 1130


>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
          Length = 984

 Score = 1039 bits (2687), Expect = 0.0
 Identities = 519/987 (52%), Positives = 688/987 (69%), Gaps = 35/987 (3%)

Query: 26  SAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLR 85
           + A  E  L+DT T   + GW   PA GW+ ++  DE+   I TYQVCNV  PNQNNWL 
Sbjct: 14  AVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLL 73

Query: 86  TSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLG----ASTQESQ 141
           T+++ R GA R+Y E++FT+RDC+S+P V G+CKETFNLYY E+D  +     A   E+ 
Sbjct: 74  TTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAP 133

Query: 142 FLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYY 201
           +LK+DTIAADESF+  D G R +K+NTEVRS GPL++ GFYLAFQD GAC+++LS+R+++
Sbjct: 134 YLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFF 193

Query: 202 KKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKC 260
           KKCP++V+N A F E +TGA+S+SLV  RG C+ ++EE D P K+YC+ +GEW+VPIG+C
Sbjct: 194 KKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRC 253

Query: 261 VCSAGYE-ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALD 319
            C  GYE E   AC AC  G +K++   + C+ CP +S S A A+  C C   YYRA  D
Sbjct: 254 TCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFD 313

Query: 320 PPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEAC 379
           PP  ACT  PS P N+IS VN TS+ LEW PP + GGR D+TYN +C++C      C  C
Sbjct: 314 PPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRC 373

Query: 380 GSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAA 439
                FVP+Q  L +  + +++L AH  Y+F I+A+NGVS  SP P +   VNITTNQAA
Sbjct: 374 DDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAA 433

Query: 440 PSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATV 499
           PS V ++ Q  A   S++L W +PEQPNGIIL+YEI+YYEK+    + S  ++ T  A +
Sbjct: 434 PSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARI 493

Query: 500 SGLKPGTRYVFQVRARTSAGCGRFSQAMEVET-----GKPRPRYDTRTIVWICLTLITGL 554
            GL+PG  YV QVRART AG G+FS  M  +T      K   R     I       +  +
Sbjct: 494 DGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFV 553

Query: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
           V L+ + I   R   YSK    SD+ + HY  G+  P +              + Y +P 
Sbjct: 554 VSLVAISIVCSRKRAYSKEAVYSDKLQ-HYSTGRGSPGM--------------KIYIDPF 598

Query: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
           TYE+P  A R F +EI+ S + IE++IG+G+ GEV  GRL++PG+R++ VAIK LKAGY+
Sbjct: 599 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYS 658

Query: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
           E+QRRDFLSEASIMGQFDHPNIIRLEGVVT+ R  MI+TE+MENG+LD+FLR +DGQFT+
Sbjct: 659 EKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTV 718

Query: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD-PDAAY 793
           +QLVGMLRG+ AGM+YL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSR L+DD  D  Y
Sbjct: 719 IQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTY 778

Query: 794 TTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE 852
           T++ GGKIP+RWTAPEAIA+R F+SASDVWS+G+VMWEV+++GERPYW+M+N+DVI+++E
Sbjct: 779 TSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIE 838

Query: 853 EGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCP 912
           + YRLP PM CP ALHQLMLDCW KDR  RPRF++IV+ LD +IR+P SL+  AT++  P
Sbjct: 839 QDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVP 898

Query: 913 -PPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVR 971
             P   RS  D    +      TV DWL +I+M +YRD F   G++SL +V +M ++D+ 
Sbjct: 899 SQPLLDRSIPDFTAFT------TVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLL 952

Query: 972 ALGITLMGHQKKILGSIQTMRAQLTST 998
            +GITL GHQKKIL SI +MR Q++ +
Sbjct: 953 RIGITLAGHQKKILNSIHSMRVQISQS 979


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 509/988 (51%), Positives = 689/988 (69%), Gaps = 43/988 (4%)

Query: 31  EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
           E  L+D++T   + GW+ +P  GW+ ++  DE+   I TYQVCNV   +QNNWLRT ++ 
Sbjct: 20  EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79

Query: 91  RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGAST----QESQFLKID 146
           R GA R++ E+KF++RDC+S+P V G+CKETFNLYY E+D D    T     E+ ++K+D
Sbjct: 80  RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139

Query: 147 TIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPA 206
           TIAADESF+  DLG R +K+NTEVRS GP+S+ GFYLAFQD G C++++++R++Y+KCP 
Sbjct: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199

Query: 207 MVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKCVCSAG 265
           +++N A F E ++GA+S+SLV  RG C+ ++EE D P K+YC+ +GEWLVPIG+C+C AG
Sbjct: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259

Query: 266 YE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323
           +E  E    C  C  G +K+  GD+ C  CP +S + +  A  C C   YYRA LDP   
Sbjct: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319

Query: 324 ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383
            CT  PSAP  +ISSVN TS+ LEW PP D GGR D+ YN +C+ C      C  CG   
Sbjct: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379

Query: 384 RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQV 443
           ++ P+Q  L +  + +++LLAH  Y+F I+AVNGV+D SP   + A VNITTNQAAPS V
Sbjct: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439

Query: 444 VVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLK 503
            ++ Q      S++L W +P+QPNG+IL+YE++YYEK+    + + +K+ T   TV GLK
Sbjct: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499

Query: 504 PGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITG---------L 554
            G  YVFQVRART AG GR+S  M  +T       + +T +   L LI G         +
Sbjct: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQT---MTEAEYQTSIQEKLPLIIGSSAAGLVFLI 556

Query: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
            V+++ ++C +R  G+ +A  +  ++  HY +G          H  PG     + Y +P 
Sbjct: 557 AVVVIAIVCNRRR-GFERADSEYTDKLQHYTSG----------HMTPGM----KIYIDPF 601

Query: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
           TYE+P  A R F +EI+ S + IE++IG+G+ GEVC G L++PG+R++ VAIK LK+GYT
Sbjct: 602 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 661

Query: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
           E+QRRDFLSEASIMGQFDHPN+I LEGVVT+    MI+TE+MENGSLD+FLR +DGQFT+
Sbjct: 662 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 721

Query: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD-PDAAY 793
           +QLVGMLRG+ AGM+YL+D+ YVHRDLAARN+LV+SNLVCKVSDFGLSR LEDD  D  Y
Sbjct: 722 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 781

Query: 794 TTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE 852
           T+  GGKIPIRWTAPEAI +R F+SASDVWS+G+VMWEV++YGERPYW+MTN+DVI+++E
Sbjct: 782 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 841

Query: 853 EGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSR-C 911
           + YRLP PM CP ALHQLMLDCW KDR  RP+F QIV+ LD +IR+P SL+A A +S   
Sbjct: 842 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 901

Query: 912 PPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVR 971
             P   R+  D    +      TV +WL++I+MG+Y++ FA  G++S  +V +M  +D+ 
Sbjct: 902 NLPLLDRTIPDYTSFN------TVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDIL 955

Query: 972 ALGITLMGHQKKILGSIQTMRAQLTSTQ 999
            +G+TL GHQKKIL SIQ MRAQ+   Q
Sbjct: 956 RVGVTLAGHQKKILNSIQVMRAQMNQIQ 983


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
           sapiens]
          Length = 986

 Score = 1033 bits (2671), Expect = 0.0
 Identities = 509/988 (51%), Positives = 689/988 (69%), Gaps = 44/988 (4%)

Query: 31  EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
           E  L+D++T   + GW+ +P  GW+ ++  DE+   I TYQVCNV   +QNNWLRT ++ 
Sbjct: 20  EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79

Query: 91  RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGAST----QESQFLKID 146
           R GA R++ E+KF++RDC+S+P V G+CKETFNLYY E+D D    T     E+ ++K+D
Sbjct: 80  RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139

Query: 147 TIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPA 206
           TIAADESF+  DLG R +K+NTEVRS GP+S+ GFYLAFQD G C++++++R++Y+KCP 
Sbjct: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199

Query: 207 MVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKCVCSAG 265
           +++N A F E ++GA+S+SLV  RG C+ ++EE D P K+YC+ +GEWLVPIG+C+C AG
Sbjct: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259

Query: 266 YE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323
           +E  E    C  C  G +K+  GD+ C  CP +S + +  A  C C   YYRA LDP   
Sbjct: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319

Query: 324 ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383
            CT  PSAP  +ISSVN TS+ LEW PP D GGR D+ YN +C+ C      C  CG   
Sbjct: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379

Query: 384 RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQV 443
           ++ P+Q  L +  + +++LLAH  Y+F I+AVNGV+D SP   + A VNITTNQAAPS V
Sbjct: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439

Query: 444 VVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLK 503
            ++ Q      S++L W +P+QPNG+IL+YE++YYEK+    + + +K+ T   TV GLK
Sbjct: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499

Query: 504 PGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITG---------L 554
            G  YVFQVRART AG GR+S  M  +T       + +T +   L LI G         +
Sbjct: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQT---MTEAEYQTSIQEKLPLIIGSSAAGLVFLI 556

Query: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
            V+++ ++C +R  G+ +A  +  ++  HY +G          H  PG     + Y +P 
Sbjct: 557 AVVVIAIVCNRR--GFERADSEYTDKLQHYTSG----------HMTPGM----KIYIDPF 600

Query: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
           TYE+P  A R F +EI+ S + IE++IG+G+ GEVC G L++PG+R++ VAIK LK+GYT
Sbjct: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660

Query: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
           E+QRRDFLSEASIMGQFDHPN+I LEGVVT+    MI+TE+MENGSLD+FLR +DGQFT+
Sbjct: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720

Query: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD-PDAAY 793
           +QLVGMLRG+ AGM+YL+D+ YVHRDLAARN+LV+SNLVCKVSDFGLSR LEDD  D  Y
Sbjct: 721 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 780

Query: 794 TTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE 852
           T+  GGKIPIRWTAPEAI +R F+SASDVWS+G+VMWEV++YGERPYW+MTN+DVI+++E
Sbjct: 781 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 840

Query: 853 EGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSR-C 911
           + YRLP PM CP ALHQLMLDCW KDR  RP+F QIV+ LD +IR+P SL+A A +S   
Sbjct: 841 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 900

Query: 912 PPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVR 971
             P   R+  D    +      TV +WL++I+MG+Y++ FA  G++S  +V +M  +D+ 
Sbjct: 901 NLPLLDRTIPDYTSFN------TVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDIL 954

Query: 972 ALGITLMGHQKKILGSIQTMRAQLTSTQ 999
            +G+TL GHQKKIL SIQ MRAQ+   Q
Sbjct: 955 RVGVTLAGHQKKILNSIQVMRAQMNQIQ 982


>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score =  991 bits (2562), Expect = 0.0
 Identities = 514/1020 (50%), Positives = 688/1020 (67%), Gaps = 60/1020 (5%)

Query: 2   APARGRLP--PALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINE 59
           +P  G LP  P L ++      A C +    E  L+DT  +  +  W ++P  GW+ ++ 
Sbjct: 11  SPPPGLLPLLPPLLLLPLLLLPAGCRAL---EETLMDTKWVTSELAWTSHPESGWEEVSG 67

Query: 60  VDESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCK 119
            DE+  PI TYQVCNV   +QNNWLRT ++ R   +RVY E+KFT+RDCNS+P + G+CK
Sbjct: 68  YDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCK 127

Query: 120 ETFNLYYLESDRDLGASTQ----ESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGP 175
           ETFNL+Y E+D D+ +++     E+ ++K+DTIA DESF+  D G    ++NT+VRS GP
Sbjct: 128 ETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGP 183

Query: 176 LSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVR 235
           LSK GFYLAFQD GAC++++S+R +YKKC +     A F E +TGA+ +SLV   G C+ 
Sbjct: 184 LSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIP 243

Query: 236 HSEERDTP-KMYCSAEGEWLVPIGKCVCSAGYEE--RRDACVACELGFYKSAPGDQLCAR 292
           ++ E   P K+YC+ +GEW+VP+G C C+ G+E   +   C  C  G YK+  G+  C  
Sbjct: 244 NAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLP 303

Query: 293 CPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPL 352
           CPP+S + +PAA  C C  ++YRA  D   SACT  PS P  +IS+VN TS+ LEW+ P 
Sbjct: 304 CPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPR 363

Query: 353 DPGGRSDITYNAVCRRCPWA--LSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSF 410
           D GGR D+ YN +C++C  A   S C  C     FVP+Q  L +  + +++LLAH  Y+F
Sbjct: 364 DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423

Query: 411 WIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGII 470
            ++AVNGVS  SP P R A VNITTNQAAPS+V  +R   +  +S++L W  PE+PNG+I
Sbjct: 424 EVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVI 483

Query: 471 LEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVE 530
           L+YE+KY+EK + + S  T+ +      + GL+P  RYV QVRART AG G++S+  E E
Sbjct: 484 LDYEMKYFEKSEGIAS--TVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFE 541

Query: 531 T------GKPRPRYDTRTIVWIC---LTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEK 581
           T      G  + +     IV      L  +  +VV+ ++ + K+RH         SD E 
Sbjct: 542 TTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRH--------GSDSEY 593

Query: 582 MHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKII 641
                        L  +  PG     + Y +P TYE+P  A R F +EI+ S + IE++I
Sbjct: 594 TEK----------LQQYIAPGM----KVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVI 639

Query: 642 GSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEG 701
           G+G+ GEVC GRL+ PG+R+V VAIK LK GYTERQRRDFLSEASIMGQFDHPNIIRLEG
Sbjct: 640 GAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEG 699

Query: 702 VVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDL 761
           VVT+ R  MI+TE+MEN +LD+FLR +DGQFT++QLVGMLRG+ AGM+YLS++ YVHRDL
Sbjct: 700 VVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDL 759

Query: 762 AARNVLVDSNLVCKVSDFGLSRVLEDDP-DAAYTTT-GGKIPIRWTAPEAIAFRTFSSAS 819
           AARN+LV+SNLVCKVSDFGLSR LEDDP D  YT++ GGKIPIRWTAPEAIA+R F+SAS
Sbjct: 760 AARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSAS 819

Query: 820 DVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDR 879
           DVWS+G+VMWEV++YGERPYW+M+N+DVI++VE+ YRLP PM CP ALHQLMLDCW +DR
Sbjct: 820 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDR 879

Query: 880 AQRPRFSQIVSVLDALIRSPESLRATATV-SRCPPPAFVRSCFDLRGGSGGGGGLTVGDW 938
             RP+FSQIV+ LD LIR+  SL+  A+  S    P   R+  D    +      TVGDW
Sbjct: 880 NLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFT------TVGDW 933

Query: 939 LDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTST 998
           LD+I+MGRY++ F + G++S  +V +M A+D+  +G+TL GHQKKIL SIQ MR Q+  T
Sbjct: 934 LDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQT 993


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score =  911 bits (2354), Expect = 0.0
 Identities = 469/995 (47%), Positives = 641/995 (64%), Gaps = 37/995 (3%)

Query: 12   LWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYP-AHGWDSINEVDESFQPIHTY 70
            LW    AAAAA    A   EV LLD +   G+ GWLT+P   GWD +  +     PI+ Y
Sbjct: 13   LWGCALAAAAA----AQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMY 67

Query: 71   QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
             VCNVMS +Q+NWLRT+WV R  A R++ E+KFT+RDCNS PG   +CKETFNLYY ESD
Sbjct: 68   SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESD 127

Query: 131  RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
             D G + Q+  F KIDTIA DE    +D   R +KLN E RSVGPL+++GFYLAFQDIGA
Sbjct: 128  LDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA 187

Query: 191  CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHS---EERDTPKMYC 247
            C+A+LS+R+YYKKCP +++ LA F E + G+D+ SL  V G CV H+      + P+M+C
Sbjct: 188  CVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHC 247

Query: 248  SAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQAC 307
            + +GEWLVPIG+C+C AGYE+  DAC AC  GF+K    +  C  CP H+  +   A +C
Sbjct: 248  AVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307

Query: 308  HCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCR 367
             C+  ++RA  DP S  CTRPPSAP  L +   G  V L W PP D GGR DI Y+  C 
Sbjct: 308  ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367

Query: 368  RCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRR 427
            +C      C  C +  R+      L + S+ V++L  HMNY+F +EA NGVS L    R 
Sbjct: 368  QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RS 426

Query: 428  AAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSY 487
                +++ NQ  P +V   R E    TS+S+ W  P      + +YE+ Y +K  +  SY
Sbjct: 427  FRTASVSINQTEPPKV---RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKG-DSNSY 482

Query: 488  STLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWIC 547
            +  +      T+  L P T Y+ QV+A T  G G  S+  E +T  P    +   I  + 
Sbjct: 483  NVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVA 542

Query: 548  LTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEP 607
            + ++  LV+  +     +R              + + +  Q+P  V+        +L   
Sbjct: 543  VGVVLLLVLAGVGFFIHRR--------------RKNQRARQSPEDVYFSKSE---QLKPL 585

Query: 608  QFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVP-GQRDVPVAI 666
            + Y +PHTYE+P +A   FT EI  S +  +K+IG+G+ GEV  G L+   G+++VPVAI
Sbjct: 586  KTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAI 645

Query: 667  KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
            K LKAGYTE+QR DFL EA IMGQF H NIIRLEGV+++ +  MI+TEYMENG+LD FLR
Sbjct: 646  KTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLR 705

Query: 727  THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
              DG+F+++QLVGMLRG+ AGM+YL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSRVLE
Sbjct: 706  EKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLE 765

Query: 787  DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
            DDP+A YTT+GGKIPIRWTAPEAI++R F+SASDVWSFG+VMWEV+ YGERPYW ++N +
Sbjct: 766  DDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHE 825

Query: 847  VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
            V+ ++ +G+RLP PM CP A++QLM+ CW ++RA+RP+F+ IVS+LD LIR+P+SL+   
Sbjct: 826  VMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLK--- 882

Query: 907  TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
            T++   P   +R       GS G    TV +WL+SI+M +Y +HF A GY+++  V++M 
Sbjct: 883  TLADFDPRVSIR--LPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMT 940

Query: 967  AQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
              D++ +G+ L GHQK+I  S+  ++ Q+ +   P
Sbjct: 941  NDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIP 975


>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
           sapiens]
          Length = 495

 Score =  908 bits (2347), Expect = 0.0
 Identities = 438/438 (100%), Positives = 438/438 (100%)

Query: 1   MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV 60
           MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
Sbjct: 1   MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV 60

Query: 61  DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE 120
           DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
Sbjct: 61  DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE 120

Query: 121 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG 180
           TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
Sbjct: 121 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG 180

Query: 181 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER 240
           FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
Sbjct: 181 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER 240

Query: 241 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA 300
           DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
Sbjct: 241 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA 300

Query: 301 APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI 360
           APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
Sbjct: 301 APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI 360

Query: 361 TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD 420
           TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
Sbjct: 361 TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD 420

Query: 421 LSPEPRRAAVVNITTNQA 438
           LSPEPRRAAVVNITTNQA
Sbjct: 421 LSPEPRRAAVVNITTNQA 438


>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
          Length = 1008

 Score =  869 bits (2246), Expect = 0.0
 Identities = 454/994 (45%), Positives = 631/994 (63%), Gaps = 49/994 (4%)

Query: 31   EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
            EV LLD+     + GW   P++GW+ I+ VDE  +PI TYQVCNV+ PNQ+NWL+T W+ 
Sbjct: 35   EVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWIS 94

Query: 91   RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQE---SQFLKIDT 147
            R   +R++ E++FTLRDC+S+PG  GTCKETFN+YYLE++ DLG        S+  KIDT
Sbjct: 95   RGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDT 154

Query: 148  IAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAM 207
            IAADESFT  DLG R++KLNTEVR +GPLS+RGF+LAFQD+GAC+A++S+R+YYK+C A 
Sbjct: 155  IAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRAT 214

Query: 208  VRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIGKCVCSAG 265
            VR LA F      +  S+LVEV G CV HSE      P+M+C A+GEWLVP+G+C CSAG
Sbjct: 215  VRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAG 274

Query: 266  YEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSAC 325
            ++ER D C AC  GFYK +P   LC+ CP HS +   A+  C C  SY R+  DPPS++C
Sbjct: 275  FQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASC 334

Query: 326  TRPPSAPVNLISSVNGTSVTLE--WAPPLDPGGRSDITYNAVCRRC--PWALSRCEACGS 381
            TRPPSAP +L  S++ + + L   W PP D GGRSD+TY+ +C RC        CE CG 
Sbjct: 335  TRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGP 394

Query: 382  GTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRA-AVVNITTNQAAP 440
               F+P+Q  L + +  + +L     Y+  + A+NGVS  +       A V ++T   AP
Sbjct: 395  RVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAP 454

Query: 441  SQVVVIRQERAGQTSVSLLWQEP---EQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRA 497
             +   IR++R    SVSL W+EP     P     EYEI+YYEK +  Q+YS +K      
Sbjct: 455  WEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTV 514

Query: 498  TVSGLKPGTRYVFQVRART---SAGCGRFSQAMEVET-------GKPRPRYDTRTIVWIC 547
            TV+ LKP TRYVFQ+RA +   S     F+ ++EV+T        + +      T+V I 
Sbjct: 515  TVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTIS 574

Query: 548  LTLITGLVVLLLLLICKKRHCGYSKAFQDS-DEEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
              L+ G V+ +L +   +R C Y K   D+ DEE++++                  K+P 
Sbjct: 575  ALLVLGSVMSVLAIW--RRPCSYGKGGGDAHDEEELYFHF----------------KVPT 616

Query: 607  PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
             + + +P +  +  +A   F +E++A  + +E+ +G G  GE+C G L++PG++++ VA+
Sbjct: 617  RRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAV 676

Query: 667  KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
              L+   ++ QR  FL+EA  +GQFDH +I+RLEGVVTRG   MIVTEYM +G+LD FLR
Sbjct: 677  HMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLR 736

Query: 727  THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
             H+GQ    QL+G+L G+ + M+YLS++GYVHR LAAR+VLV S+LVCK+S FG  R   
Sbjct: 737  RHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPR 794

Query: 787  DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
            D  +A YTT  G+ P  W APE + F  FSSASDVWSFG++MWEV+A+GERPYW+M+ +D
Sbjct: 795  DRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQD 854

Query: 847  VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
            VI +VE+G+RLP P  CP+ LH+LMLDCW KD  +RPRFSQI S+L  +++ PE  +   
Sbjct: 855  VIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCAL 914

Query: 907  TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
            T    PP       F      G     +VG WL+++ + RY+D FAA GY SL  V  M 
Sbjct: 915  TTCPRPPTPLADRAFSTFPSFG-----SVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMT 969

Query: 967  AQDVRALGITLMGHQKKILGSIQTMRAQLTSTQG 1000
            AQD+ +LGI+L  H++ +L  I  ++A++   QG
Sbjct: 970  AQDLVSLGISLAEHREALLSGISALQARVLQLQG 1003


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score =  850 bits (2197), Expect = 0.0
 Identities = 457/988 (46%), Positives = 624/988 (63%), Gaps = 49/988 (4%)

Query: 27  AARGEVNLLDTSTIHGDWGWLTYPAHG--WDSINEVDESFQPIHTYQVCNVM-SPNQNNW 83
           AA  E  LL+T     D  W+T+P     W+ ++ +DE    + TY+VC+V  +P Q +W
Sbjct: 13  AAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHW 72

Query: 84  LRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRD----LGASTQE 139
           LRT WVPR GA  VYA ++FT+ +C S+P    +CKETF ++Y ESD D    L  +  E
Sbjct: 73  LRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWME 132

Query: 140 SQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRI 199
           + ++K+DT+AA+             K+N +   +GPLSK GFYLAFQD GAC+A+LSL +
Sbjct: 133 NPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHL 192

Query: 200 YYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERD--TPKMYCSAEGEWLV-P 256
           +YKKC  +  NL  F E V       +V V G CV  +      +P +YC  +G+W   P
Sbjct: 193 FYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQP 249

Query: 257 IGKCVCSAGYE--ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYY 314
           +  C C+ G+E  E    C AC  G +K   G+  C  CP +SHS    +  C C + Y+
Sbjct: 250 VTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYF 309

Query: 315 RAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALS 374
           RA  DP  + CT PPSAP +++S +NG+S+ LEW+ PL+ GGR D+TY   CR C    S
Sbjct: 310 RARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGS 369

Query: 375 RCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNIT 434
            C  CG    F P    LV+  ++V  L     Y+F + A+NGVS L+  P     VN+T
Sbjct: 370 -CAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVT 428

Query: 435 TNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKE-MQSYSTLKAV 493
           T++  P  V  IR  R+  +S+SL W  P  P+G +L+YE+KY+EK  E   S   LK  
Sbjct: 429 TDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTS 488

Query: 494 TTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWICLTLITG 553
             RA + GLK G  Y+ QVRAR+ AG G F Q    +T           +  I  T + G
Sbjct: 489 ENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLALIAGTAVVG 548

Query: 554 LVVLLLLLIC-----KKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQ 608
           +V++L++++      +K+  G    + D        ++GQ     +L  H         +
Sbjct: 549 VVLVLVVIVVAVLCLRKQSNGREAEYSD--------KHGQ-----YLIGHGT-------K 588

Query: 609 FYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKA 668
            Y +P TYE+P  A R F +EI+ S + IE++IG+G+ GEVC GRL+ PG+++  VAIK 
Sbjct: 589 VYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKT 648

Query: 669 LKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTH 728
           LK GYTERQRR+FLSEASIMGQF+HPNIIRLEGVVT     MI+TE+MENG+LD+FLR +
Sbjct: 649 LKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLN 708

Query: 729 DGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD 788
           DGQFT++QLVGMLRG+ +GMRYL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSR LE++
Sbjct: 709 DGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEEN 768

Query: 789 -PDAAYTTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
             D  YT++ GGKIPIRWTAPEAIAFR F+SASD WS+G+VMWEV+++GERPYW+M+N+D
Sbjct: 769 SSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQD 828

Query: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
           VI+++E+ YRLP P  CP +LHQLMLDCW KDR  RPRF Q+VS LD +IR+P SL+  A
Sbjct: 829 VINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVA 888

Query: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
             +            D R       G +VG+WL +I+MGRY + FAA G+ S  +V +++
Sbjct: 889 REN----GGASHPLLDQRQPHYSAFG-SVGEWLRAIKMGRYEESFAAAGFGSFELVSQIS 943

Query: 967 AQDVRALGITLMGHQKKILGSIQTMRAQ 994
           A+D+  +G+TL GHQKKIL S+Q M++Q
Sbjct: 944 AEDLLRIGVTLAGHQKKILASVQHMKSQ 971


>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
          Length = 1021

 Score =  739 bits (1909), Expect = 0.0
 Identities = 409/1047 (39%), Positives = 605/1047 (57%), Gaps = 114/1047 (10%)

Query: 11   ALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
            +LWV+   ++          E  LLDT+    + GWLTYP  GWD ++ +D+  +   T+
Sbjct: 19   SLWVLLLVSSVLAL------EEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTF 72

Query: 71   QVCNVMSP----NQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYY 126
            + C+V        Q+NWL+T +V R GA+R +  + F++R C+S+    GTC+ETF LYY
Sbjct: 73   EACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYY 132

Query: 127  LESDR----DLGASTQESQFLKIDTIAADESFTGAD-----------------LGVRR-L 164
             +++     D  +S    ++ K+DTIAADESF  +                   G R  L
Sbjct: 133  RQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGL 192

Query: 165  KLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEA-VTGADS 223
            +LN + RS GPL++RGFY+AFQD GACLA++++R++   CPA++R+ A+F E   +GA  
Sbjct: 193  QLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGG 252

Query: 224  SSLVEVRGQCVRHSEERDT----------PKMYCSAEGEWLVPIGKCVCSAGYEERRD-- 271
            +SLV   G CV H+E  +           P+++C+ EG+W+V +G C C  GY+  R   
Sbjct: 253  ASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDK 312

Query: 272  ACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSA 331
            AC AC  G YKS+ G+  C+ CP  SH+  PAA  C C   +YRA+ DPP + CT PPSA
Sbjct: 313  ACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSA 372

Query: 332  PVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALS-------RCEACGSGTR 384
            P  L   V G+++ L W  P + GGR D+ +N VC+ C             C  C     
Sbjct: 373  PQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVH 432

Query: 385  FVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVV 444
            F P+Q  L ++ +LV  L AH+ Y   ++AVNGVS+LSP+P +AA +N++T+   PS V 
Sbjct: 433  FDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVP 492

Query: 445  VIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKP 504
            V+ Q      S+++ W +P+Q NG IL+Y+++YY++ ++     TL + T  ATV+ L P
Sbjct: 493  VVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSP 552

Query: 505  GTRYVFQVRARTSAGCGRFSQAMEVET---GKPRPRYDTRTIVWI-------CLTLITGL 554
            G  Y FQVRART+AG G +   +  +T   G+   +   R  + I          L+  +
Sbjct: 553  GHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAI 612

Query: 555  VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
             VL ++   K+R  GY++  Q                      +  PG     ++Y +P 
Sbjct: 613  TVLAVVFQRKRRGTGYTEQLQQ---------------------YSSPGL--GVKYYIDPS 649

Query: 615  TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
            TYE+P +A R   RE++ + I IE++IG+G  GEV  GRL+  G+R+  VAI+AL AG  
Sbjct: 650  TYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGA 709

Query: 675  ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
            E  +  FL  A+++GQF HPNI+RLEGVVT+ R  M++TE+ME G LD+FLR  +GQF+ 
Sbjct: 710  ESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSS 769

Query: 735  MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYT 794
            +QLV M RGV A M+YLS   +VHR L+A +VLV+S+LVCKV+  G            ++
Sbjct: 770  LQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG------------HS 817

Query: 795  TTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEG 854
              G    +RW APE IA    +++SDVWSFG++MWEV++YGERPYW+M+ ++V++++E+ 
Sbjct: 818  PQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQE 877

Query: 855  YRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCP-- 912
            +RLP P GCP  LH LMLD W KDRA+RP F Q+V+  D +IR P++L+A       P  
Sbjct: 878  FRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQ 937

Query: 913  ----PPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQ 968
                P A    C D           +   WL +I +  Y+D+F+  G  +   V +++ +
Sbjct: 938  ALLTPVALDFPCLD-----------SPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLE 986

Query: 969  DVRALGITLMGHQKKILGSIQTMRAQL 995
            D+ ALGITL GHQKK+L  IQ ++  L
Sbjct: 987  DLPALGITLAGHQKKLLHHIQLLQQHL 1013


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score =  726 bits (1875), Expect = 0.0
 Identities = 411/983 (41%), Positives = 572/983 (58%), Gaps = 61/983 (6%)

Query: 31  EVNLLDTSTIHGDWGWLTYPAH-GWDSINEVDESFQPIHTYQVCNVMSPNQ-NNWLRTSW 88
           EV L+DTS   G+ GWL  P   GW    ++     P++ YQ C +      ++WLR++W
Sbjct: 27  EVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG-TPLYMYQDCPMQGRRDTDHWLRSNW 85

Query: 89  VPR-DGARRVYAEIKFTLRDCNSMPGVLGT--CKETFNLYYLESDRDLGASTQESQFLKI 145
           + R + A RV+ E++FT+RDC S PG  G   CKETFNL Y+ESD+D+G   +   F K+
Sbjct: 86  IYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLFQKV 145

Query: 146 DTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCP 205
            T+AAD+SFT  DL    +KLN E  S+G L++RG YLAF + GAC+A++S+R++Y++CP
Sbjct: 146 TTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCP 205

Query: 206 AMVRNLAAFSEAVTGADSSSLVEVRGQCVRHS----EERDTPKMYCSAEGEWLVPIGKCV 261
             +  LA F + + G   + LVEV G C+ H+         P+M+CS +GEWLVP+G+C 
Sbjct: 206 ETLNGLAQFPDTLPG--PAGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCH 263

Query: 262 CSAGYEE--RRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALD 319
           C  GYEE    +ACVAC  G Y+       C  CP  S + +  A  C C+  +YRA  +
Sbjct: 264 CEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRAPGE 323

Query: 320 PPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWAL---SRC 376
            P  ACT PPSAP NL  S +GT ++L W PP D GGR D+ Y+  C +C         C
Sbjct: 324 GPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPC 383

Query: 377 EACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTN 436
           + CG G  F P    L   ++ V  L  + NY+F +EA NGVS L      +  V+I+  
Sbjct: 384 QPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMG 443

Query: 437 QAAPSQVVVIRQERAGQTSVSLLW--QEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVT 494
            A     + +R  +     + L W    P  P G  L YE+    +D+E         + 
Sbjct: 444 HAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYELHVLNQDEERYQ----MVLE 498

Query: 495 TRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT-RTIVWICLTLITG 553
            R  ++ L+P T Y+ +VR  T  G G FS   E  T  P  R  T   IV +   L+ G
Sbjct: 499 PRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLLG 558

Query: 554 LVVLLLLLICKKRHCGYSKAFQDSD-------EEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
             +LL +L+ + R     +  +  D       E+K+  +                     
Sbjct: 559 AALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKP-------------------- 598

Query: 607 PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
              Y +   YE+P +    FTRE++ + + ++ +IG G+ GEV  G LR+P Q    VAI
Sbjct: 599 ---YVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAI 655

Query: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
           K LK      Q  +FL EA+IMGQF HP+I+ LEGVVT+ +  MI+TE+MENG+LD FLR
Sbjct: 656 KTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLR 715

Query: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
             + Q    QLV ML+G+ +GM YLS+  YVHRDLAARN+LV+ NL CKVSDFGL+R+L 
Sbjct: 716 EREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL- 774

Query: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
           DD D  Y T GGKIPIRWTAPEAIA R F++ASDVWSFG+VMWEVL++G++PY  M+N++
Sbjct: 775 DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQE 834

Query: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
           V+ S+E+GYRLP P+ CP  L++LM +CW  DRA+RP F ++ + L+ L+ +P SLR   
Sbjct: 835 VMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLR--- 891

Query: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
           T++   P   +R       GS G    TV +WL+SIRM RY  HF + G  ++  VL + 
Sbjct: 892 TIANFDPRMTLR--LPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELT 949

Query: 967 AQDVRALGITLMGHQKKILGSIQ 989
           A+D+  +GITL GHQK+IL SIQ
Sbjct: 950 AEDLTQMGITLPGHQKRILCSIQ 972


>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
           sapiens]
          Length = 539

 Score =  662 bits (1707), Expect = 0.0
 Identities = 305/501 (60%), Positives = 387/501 (77%), Gaps = 1/501 (0%)

Query: 31  EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
           EVNLLD+ TI G+ GW++YP+HGW+ I+ VDE + PI TYQVCNVM  +QNNWLRT+WVP
Sbjct: 29  EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88

Query: 91  RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAA 150
           R+ A+++Y E+KFTLRDCNS+P VLGTCKETFNLYY+ESD D G   +E QF KIDTIAA
Sbjct: 89  RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAA 148

Query: 151 DESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRN 210
           DESFT  DLG R LKLNTE+R VGP++K+GFYLAFQD+GAC+A++S+R+Y+KKCP  V+N
Sbjct: 149 DESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKN 208

Query: 211 LAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERR 270
           LA F + V   DS SLVEVRG CV +S+E D P+MYCS EGEWLVPIGKC C+AGYEER 
Sbjct: 209 LAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERG 267

Query: 271 DACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPS 330
             C AC  GFYK+  G+  CA+CPPHS +    +  C C+ +Y+RA  DPPS ACTRPPS
Sbjct: 268 FMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPS 327

Query: 331 APVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQT 390
           +P N+IS++N TSV L+W+ PLD GGR D+T+N +C++C W + +CE C    RF+P+Q 
Sbjct: 328 SPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387

Query: 391 SLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQER 450
            L   ++ V +LLAH NY+F I+AVNGVS+LS  PR+ A V+ITTNQAAPS V+ I+++R
Sbjct: 388 GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447

Query: 451 AGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVF 510
             + S+SL WQEPE PNGIIL+YE+KYYEK ++  SY+ L+A  T  T+S LKP T YVF
Sbjct: 448 TSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVF 507

Query: 511 QVRARTSAGCGRFSQAMEVET 531
           Q+RART+AG G  S+  E ET
Sbjct: 508 QIRARTAAGYGTNSRKFEFET 528


>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
          Length = 295

 Score =  306 bits (784), Expect = 6e-83
 Identities = 142/253 (56%), Positives = 186/253 (73%), Gaps = 5/253 (1%)

Query: 31  EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
           EV LLD+     + GW   P++GW+ I+ VDE  +PI TYQVCNV+ PNQ+NWL+T W+ 
Sbjct: 35  EVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWIS 94

Query: 91  RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQE---SQFLKIDT 147
           R   +R++ E++FTLRDC+S+PG  GTCKETFN+YYLE++ DLG        S+  KIDT
Sbjct: 95  RGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDT 154

Query: 148 IAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAM 207
           IAADESFT  DLG R++KLNTEVR +GPLS+RGF+LAFQD+GAC+A++S+R+YYK+C A 
Sbjct: 155 IAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRAT 214

Query: 208 VRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIGKCVCSAG 265
           VR LA F      +  S+LVEV G CV HSE      P+M+C A+GEWLVP+G+C CSAG
Sbjct: 215 VRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAG 274

Query: 266 YEERRDACVACEL 278
           ++ER D C   +L
Sbjct: 275 FQERGDFCEGIQL 287


>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
          Length = 1074

 Score =  217 bits (552), Expect = 5e-56
 Identities = 119/296 (40%), Positives = 166/296 (56%), Gaps = 3/296 (1%)

Query: 606 EPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVA 665
           E   YAE    E+      +   EI+  RI + + IG G  G+V  G    P    + VA
Sbjct: 415 ETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVA 474

Query: 666 IKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFL 725
           IK  K   ++  R  FL EA  M QFDHP+I++L GV+T   +  I+ E    G L +FL
Sbjct: 475 IKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTLGELRSFL 533

Query: 726 RTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVL 785
           +       +  L+     +   + YL    +VHRD+AARNVLV SN   K+ DFGLSR +
Sbjct: 534 QVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM 593

Query: 786 EDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNR 845
           ED     Y  + GK+PI+W APE+I FR F+SASDVW FGV MWE+L +G +P+  + N 
Sbjct: 594 EDS--TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNN 651

Query: 846 DVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPES 901
           DVI  +E G RLP P  CP  L+ LM  CW  D ++RPRF+++ + L  ++   ++
Sbjct: 652 DVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKA 707


>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
          Length = 1052

 Score =  217 bits (552), Expect = 5e-56
 Identities = 119/296 (40%), Positives = 166/296 (56%), Gaps = 3/296 (1%)

Query: 606 EPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVA 665
           E   YAE    E+      +   EI+  RI + + IG G  G+V  G    P    + VA
Sbjct: 393 ETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVA 452

Query: 666 IKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFL 725
           IK  K   ++  R  FL EA  M QFDHP+I++L GV+T   +  I+ E    G L +FL
Sbjct: 453 IKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPV-WIIMELCTLGELRSFL 511

Query: 726 RTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVL 785
           +       +  L+     +   + YL    +VHRD+AARNVLV SN   K+ DFGLSR +
Sbjct: 512 QVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYM 571

Query: 786 EDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNR 845
           ED     Y  + GK+PI+W APE+I FR F+SASDVW FGV MWE+L +G +P+  + N 
Sbjct: 572 EDS--TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNN 629

Query: 846 DVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPES 901
           DVI  +E G RLP P  CP  L+ LM  CW  D ++RPRF+++ + L  ++   ++
Sbjct: 630 DVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKA 685


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score =  210 bits (535), Expect = 5e-54
 Identities = 114/273 (41%), Positives = 161/273 (58%), Gaps = 10/273 (3%)

Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
           EI    + + K +G+G  GEV  G        +  VAIK LK G    +   FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWN----GNTKVAIKTLKPGTMSPE--SFLEEAQIM 318

Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQ-FTIMQLVGMLRGVGAG 747
            +  H  +++L  VV+   +  IVTEYM  GSL  FL+  +G+   +  LV M   V AG
Sbjct: 319 KKLKHDKLVQLYAVVSEEPI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377

Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
           M Y+  + Y+HRDL + N+LV + L+CK++DFGL+R++ED+   A    G K PI+WTAP
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTA--RQGAKFPIKWTAP 435

Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
           EA  +  F+  SDVWSFG+++ E++  G  PY  M NR+V+  VE GYR+P P  CP +L
Sbjct: 436 EAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISL 495

Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
           H+LM+ CW KD  +RP F  + S L+    + E
Sbjct: 496 HELMIHCWKKDPEERPTFEYLQSFLEDYFTATE 528


>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform B [Homo sapiens]
          Length = 491

 Score =  210 bits (534), Expect = 6e-54
 Identities = 113/273 (41%), Positives = 160/273 (58%), Gaps = 9/273 (3%)

Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
           EI    I + K +G+G  GEV  G           VA+K LK G    Q   FL EA++M
Sbjct: 220 EIPRESIKLVKRLGAGQFGEVWMGYYN----NSTKVAVKTLKPGTMSVQA--FLEEANLM 273

Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIM-QLVGMLRGVGAG 747
               H  ++RL  VVTR     I+TEYM  GSL  FL++ +G   ++ +L+     +  G
Sbjct: 274 KTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEG 333

Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
           M Y+    Y+HRDL A NVLV  +L+CK++DFGL+RV+ED+   A    G K PI+WTAP
Sbjct: 334 MAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTA--REGAKFPIKWTAP 391

Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
           EAI F  F+  SDVWSFG++++E++ YG+ PY   TN DV++++ +GYR+P    CP  L
Sbjct: 392 EAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDEL 451

Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
           + +M  CW +   +RP F  + SVLD    + E
Sbjct: 452 YDIMKMCWKEKAEERPTFDYLQSVLDDFYTATE 484


>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform A [Homo sapiens]
          Length = 512

 Score =  210 bits (534), Expect = 6e-54
 Identities = 113/273 (41%), Positives = 160/273 (58%), Gaps = 9/273 (3%)

Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
           EI    I + K +G+G  GEV  G           VA+K LK G    Q   FL EA++M
Sbjct: 241 EIPRESIKLVKRLGAGQFGEVWMGYYN----NSTKVAVKTLKPGTMSVQA--FLEEANLM 294

Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIM-QLVGMLRGVGAG 747
               H  ++RL  VVTR     I+TEYM  GSL  FL++ +G   ++ +L+     +  G
Sbjct: 295 KTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEG 354

Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
           M Y+    Y+HRDL A NVLV  +L+CK++DFGL+RV+ED+   A    G K PI+WTAP
Sbjct: 355 MAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTA--REGAKFPIKWTAP 412

Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
           EAI F  F+  SDVWSFG++++E++ YG+ PY   TN DV++++ +GYR+P    CP  L
Sbjct: 413 EAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDEL 472

Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
           + +M  CW +   +RP F  + SVLD    + E
Sbjct: 473 YDIMKMCWKEKAEERPTFDYLQSVLDDFYTATE 505


>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
          Length = 526

 Score =  210 bits (534), Expect = 6e-54
 Identities = 115/305 (37%), Positives = 174/305 (57%), Gaps = 10/305 (3%)

Query: 598 HHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVP 657
           H+  G     Q  + P    +P +       EI    + +EK +G+G  GEV        
Sbjct: 225 HYKKGNDGLCQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYN-- 282

Query: 658 GQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYME 717
             +   VA+K +K G    +   FL+EA++M    H  +++L  VVT+  +  I+TE+M 
Sbjct: 283 --KHTKVAVKTMKPGSMSVEA--FLAEANVMKTLQHDKLVKLHAVVTKEPI-YIITEFMA 337

Query: 718 NGSLDTFLRTHDG-QFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKV 776
            GSL  FL++ +G +  + +L+     +  GM ++    Y+HRDL A N+LV ++LVCK+
Sbjct: 338 KGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKI 397

Query: 777 SDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGE 836
           +DFGL+RV+ED+   A    G K PI+WTAPEAI F +F+  SDVWSFG+++ E++ YG 
Sbjct: 398 ADFGLARVIEDNEYTA--REGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR 455

Query: 837 RPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALI 896
            PY  M+N +VI ++E GYR+P P  CP  L+ +M+ CW     +RP F  I SVLD   
Sbjct: 456 IPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFY 515

Query: 897 RSPES 901
            + ES
Sbjct: 516 TATES 520


>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
          Length = 543

 Score =  210 bits (534), Expect = 6e-54
 Identities = 118/273 (43%), Positives = 158/273 (57%), Gaps = 10/273 (3%)

Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
           EI    + +E  +G G  GEV  G           VAIK LK G    +   FL EA IM
Sbjct: 271 EIPRESLRLEVKLGQGCFGEVWMGTWN----GTTKVAIKTLKPGTMMPEA--FLQEAQIM 324

Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFT-IMQLVGMLRGVGAG 747
            +  H  ++ L  VV+   +  IVTE+M  GSL  FL+  DG++  + QLV M   +  G
Sbjct: 325 KKLRHDKLVPLYAVVSEEPI-YIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADG 383

Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
           M Y+  + Y+HRDL A N+LV  NLVCK++DFGL+R++ED+   A    G K PI+WTAP
Sbjct: 384 MAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTA--RQGAKFPIKWTAP 441

Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
           EA  +  F+  SDVWSFG++  E++  G  PY  M NR+V+  VE GYR+P P GCP +L
Sbjct: 442 EAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESL 501

Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
           H+LM  CW KD  +RP F  I S L+    + E
Sbjct: 502 HELMNLCWKKDPDERPTFEYIQSFLEDYFTATE 534


>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  209 bits (532), Expect = 1e-53
 Identities = 114/273 (41%), Positives = 164/273 (60%), Gaps = 10/273 (3%)

Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
           E+    + + + +G+G  GEV  G           VA+K+LK G        FL+EA++M
Sbjct: 239 EVPRETLKLVERLGAGQFGEVWMGYYN----GHTKVAVKSLKQGSMSPDA--FLAEANLM 292

Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDG-QFTIMQLVGMLRGVGAG 747
            Q  H  ++RL  VVT+  +  I+TEYMENGSL  FL+T  G + TI +L+ M   +  G
Sbjct: 293 KQLQHQRLVRLYAVVTQEPI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351

Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
           M ++ +  Y+HRDL A N+LV   L CK++DFGL+R++ED+   A    G K PI+WTAP
Sbjct: 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTA--REGAKFPIKWTAP 409

Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
           EAI + TF+  SDVWSFG+++ E++ +G  PY  MTN +VI ++E GYR+  P  CP  L
Sbjct: 410 EAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEEL 469

Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
           +QLM  CW +    RP F  + SVL+    + E
Sbjct: 470 YQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 502


>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  209 bits (532), Expect = 1e-53
 Identities = 114/273 (41%), Positives = 164/273 (60%), Gaps = 10/273 (3%)

Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
           E+    + + + +G+G  GEV  G           VA+K+LK G        FL+EA++M
Sbjct: 239 EVPRETLKLVERLGAGQFGEVWMGYYN----GHTKVAVKSLKQGSMSPDA--FLAEANLM 292

Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDG-QFTIMQLVGMLRGVGAG 747
            Q  H  ++RL  VVT+  +  I+TEYMENGSL  FL+T  G + TI +L+ M   +  G
Sbjct: 293 KQLQHQRLVRLYAVVTQEPI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351

Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
           M ++ +  Y+HRDL A N+LV   L CK++DFGL+R++ED+   A    G K PI+WTAP
Sbjct: 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTA--REGAKFPIKWTAP 409

Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
           EAI + TF+  SDVWSFG+++ E++ +G  PY  MTN +VI ++E GYR+  P  CP  L
Sbjct: 410 EAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEEL 469

Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
           +QLM  CW +    RP F  + SVL+    + E
Sbjct: 470 YQLMRLCWKERPEDRPTFDYLRSVLEDFFTATE 502


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  208 bits (529), Expect = 2e-53
 Identities = 116/273 (42%), Positives = 158/273 (57%), Gaps = 10/273 (3%)

Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
           EI    + +E  +G G  GEV  G      +    VAIK LK G    +   FL EA +M
Sbjct: 264 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTMSPEA--FLQEAQVM 317

Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFT-IMQLVGMLRGVGAG 747
            +  H  +++L  VV+   +  IVTEYM  GSL  FL+   G++  + QLV M   + +G
Sbjct: 318 KKLRHEKLVQLYAVVSEEPI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASG 376

Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
           M Y+  + YVHRDL A N+LV  NLVCKV+DFGL+R++ED+   A    G K PI+WTAP
Sbjct: 377 MAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA--RQGAKFPIKWTAP 434

Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
           EA  +  F+  SDVWSFG+++ E+   G  PY  M NR+V+  VE GYR+P P  CP +L
Sbjct: 435 EAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESL 494

Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
           H LM  CW K+  +RP F  + + L+    S E
Sbjct: 495 HDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTE 527


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  208 bits (529), Expect = 2e-53
 Identities = 116/273 (42%), Positives = 158/273 (57%), Gaps = 10/273 (3%)

Query: 629 EIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIM 688
           EI    + +E  +G G  GEV  G      +    VAIK LK G    +   FL EA +M
Sbjct: 264 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTMSPEA--FLQEAQVM 317

Query: 689 GQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFT-IMQLVGMLRGVGAG 747
            +  H  +++L  VV+   +  IVTEYM  GSL  FL+   G++  + QLV M   + +G
Sbjct: 318 KKLRHEKLVQLYAVVSEEPI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASG 376

Query: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAP 807
           M Y+  + YVHRDL A N+LV  NLVCKV+DFGL+R++ED+   A    G K PI+WTAP
Sbjct: 377 MAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA--RQGAKFPIKWTAP 434

Query: 808 EAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHAL 867
           EA  +  F+  SDVWSFG+++ E+   G  PY  M NR+V+  VE GYR+P P  CP +L
Sbjct: 435 EAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESL 494

Query: 868 HQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE 900
           H LM  CW K+  +RP F  + + L+    S E
Sbjct: 495 HDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTE 527


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,728,260
Number of Sequences: 37866
Number of extensions: 2029570
Number of successful extensions: 10480
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 620
Number of HSP's successfully gapped in prelim test: 328
Number of HSP's that attempted gapping in prelim test: 6706
Number of HSP's gapped (non-prelim): 2215
length of query: 1005
length of database: 18,247,518
effective HSP length: 112
effective length of query: 893
effective length of database: 14,006,526
effective search space: 12507827718
effective search space used: 12507827718
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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