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Search of human proteins with 186928829
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
(386 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 806 0.0
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 797 0.0
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 793 0.0
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 790 0.0
gi|186928831 dermokine isoform 6 [Homo sapiens] 161 8e-40
gi|57864582 hornerin [Homo sapiens] 104 1e-22
gi|55956899 keratin 9 [Homo sapiens] 103 3e-22
gi|109255251 loricrin [Homo sapiens] 101 1e-21
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 91 1e-18
gi|195972866 keratin 10 [Homo sapiens] 91 1e-18
gi|62122917 filaggrin family member 2 [Homo sapiens] 89 7e-18
gi|119395750 keratin 1 [Homo sapiens] 88 1e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 87 2e-17
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 81 2e-15
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 81 2e-15
gi|47132620 keratin 2 [Homo sapiens] 81 2e-15
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 80 3e-15
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 78 1e-14
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 78 2e-14
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 76 6e-14
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 75 8e-14
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 74 2e-13
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 74 2e-13
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 74 2e-13
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 74 3e-13
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 74 3e-13
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 73 4e-13
gi|48762934 alpha 2 type I collagen [Homo sapiens] 73 5e-13
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 72 6e-13
gi|60593038 keratin associated protein 5-4 [Homo sapiens] 72 6e-13
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 806 bits (2082), Expect = 0.0
Identities = 386/386 (100%), Positives = 386/386 (100%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTF 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTF
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTF 360
Query: 361 WKNFKSKLGFINWDAINKDQRSSRIP 386
WKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 361 WKNFKSKLGFINWDAINKDQRSSRIP 386
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 797 bits (2059), Expect = 0.0
Identities = 386/398 (96%), Positives = 386/398 (96%), Gaps = 12/398 (3%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ------------NS 348
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ NS
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNS 360
Query: 349 ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 386
ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 361 ETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 398
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 793 bits (2048), Expect = 0.0
Identities = 379/380 (99%), Positives = 380/380 (100%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTF 360
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTF
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTF 360
Query: 361 WKNFKSKLGFINWDAINKDQ 380
WKNFKSKLGFINWDAINK+Q
Sbjct: 361 WKNFKSKLGFINWDAINKNQ 380
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 790 bits (2041), Expect = 0.0
Identities = 386/416 (92%), Positives = 386/416 (92%), Gaps = 30/416 (7%)
Query: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
Sbjct: 1 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG 60
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV
Sbjct: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
Sbjct: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
Sbjct: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
Sbjct: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS 300
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ-------------- 346
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ
Sbjct: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360
Query: 347 ----------------NSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 386
NSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP
Sbjct: 361 SKEGNRLLGGSGDNYRNSETSPGMFNFDTFWKNFKSKLGFINWDAINKDQRSSRIP 416
>gi|186928831 dermokine isoform 6 [Homo sapiens]
Length = 189
Score = 161 bits (408), Expect = 8e-40
Identities = 73/74 (98%), Positives = 74/74 (100%)
Query: 307 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKS 366
GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKS
Sbjct: 20 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKS 79
Query: 367 KLGFINWDAINKDQ 380
KLGFINWDAINK+Q
Sbjct: 80 KLGFINWDAINKNQ 93
Score = 31.6 bits (70), Expect = 1.3
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 219 SVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-------SSGSGSNGDNNNGSSSG 270
S + + + EG S G SGGG+G + G + GSG +G N+ +S G
Sbjct: 8 SDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 66
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 104 bits (260), Expect = 1e-22
Identities = 103/339 (30%), Positives = 145/339 (42%), Gaps = 42/339 (12%)
Query: 26 SGEESTGTNIGEALGH--GLGDALSEGVGKAIGKEAGGAAGSKVSEAL-GQGTREAVGTG 82
SG+ S+ + G GH G G S + G+ G ++GS G G+R++ G G
Sbjct: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG 2173
Query: 83 VRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHN--- 139
RQ G G + + G + H+ + H G G + RG ++ GH+
Sbjct: 2174 -RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGS--------GRSSSRGPYESRSGHSSVF 2224
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199
G E+ GH SQ G G G + HG + +F + +G+ GQ +
Sbjct: 2225 GQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF--DQEGSSTGQSSSH 2276
Query: 200 GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------GSGGGSSNSGGGSGSQSG 253
G G++ + Q G GS ++ ++ + S GSG G S+S G GS SG
Sbjct: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
Query: 254 -SSGSG--------SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304
SSG G S+G +GS SG SSS G SG SS G G S G S S
Sbjct: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE--RHGSSSGSSSSYG 2394
Query: 305 SWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
GS + S G HG G G+G P + G GSG+S
Sbjct: 2395 QHGSGSRQSLG-HGQHGSGSGQSPSPSR-GRHGSGSGQS 2431
Score = 103 bits (256), Expect = 3e-22
Identities = 111/346 (32%), Positives = 148/346 (42%), Gaps = 25/346 (7%)
Query: 26 SGEESTGTNIGEALGH--GLGDALSEGVGKAIGKEAGGAAGSKVSEAL-GQGTREAVGTG 82
SG+ S+ + G GH G G S + G+ G ++GS G G+R++ G G
Sbjct: 1174 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG 1233
Query: 83 VRQVPGFGAADALGNRVGEAAHAL--GNTGHEIGRQAED---VIRHGADAVRGSWQGVPG 137
RQ G G + + G H+ G G GR + R G +V G + G
Sbjct: 1234 -RQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 1292
Query: 138 HNGAWETSG-GHGIFGSQGGLG---GQG-----QGNPGGLGTPWVHGYPGNSAGSFGMNP 188
H+ A+ G G G F SQG G GQ +G+ G + + H G+S S G
Sbjct: 1293 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSS-GYGR 1351
Query: 189 QGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPSGSGGGSSNSGGG 247
GA GQ + G G+ + Q G GS +S+ G + SG G S+S
Sbjct: 1352 HGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 1411
Query: 248 SGSQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG--SRGDSGSES 304
SG SGSG S+ +GS SG SS G G SSG SS SG S G S
Sbjct: 1412 SGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1471
Query: 305 SWGSSTGSSSGNHG-GSGGGNGHKP-GCEKPGNEARGSGESGIQNS 348
G S S G HG GSG + + P G + +RG ESG +S
Sbjct: 1472 GSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHS 1517
Score = 102 bits (255), Expect = 4e-22
Identities = 106/354 (29%), Positives = 148/354 (41%), Gaps = 49/354 (13%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAG------SKVSEA 70
G GE+ E S+G + + HG G S G G+ + + G S+ S
Sbjct: 1630 GLGESSGFGHHESSSGQSSSYSQ-HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688
Query: 71 LGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA 127
GQ G+R++ G G RQ G G + + G H+ + H G G +
Sbjct: 1689 YGQHGSGSRQSSGHG-RQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS--------GRSS 1739
Query: 128 VRGSWQGVPGHN---GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF 184
RG ++ GH+ G E+ GH SQ G G G + HG + +F
Sbjct: 1740 SRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS------GHFCSQGQHGSTSGQSSTF 1793
Query: 185 GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------GSG 238
+ +G+ GQ + G G++ + Q G GS ++ ++ + S GSG
Sbjct: 1794 --DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 1851
Query: 239 GGSSNSGGGSGSQSG-SSGSG--------SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
G S+S G GS SG SSG G S+G +GS SG SSS G SG SS G
Sbjct: 1852 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911
Query: 290 SGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
G S G S S GS + S G HG G G+G P + G GSG+S
Sbjct: 1912 --QHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSR-GRHGSGSGQS 1961
Score = 100 bits (249), Expect = 2e-21
Identities = 107/357 (29%), Positives = 146/357 (40%), Gaps = 40/357 (11%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 2306 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 2365
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G R G++ + G + +LG+ H G + RHG
Sbjct: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 2425
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------GQGQG---NPGGLGTPWV 173
+ + + S G W +S G GS GLG GQ G + G
Sbjct: 2426 SGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2485
Query: 174 HGYPGNSAG-SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP 232
HG G+++G S GA GQ + G G++ + G GS ++ + +
Sbjct: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
Query: 233 PPSGSGGGSSNSGGGSGSQSGSSGSG---SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
S S G SG G S SG GSG S+G ++ SSSG SSS S G SG SSG
Sbjct: 2546 RQSPSYG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG-- 2602
Query: 290 SGNSGGSRGDSGSESSWGSSTGSSS--GNHG-GSGGGNGHKPGCEKPGNEARGSGES 343
G G G S GSS+GSSS G HG GS +GH G + GSG+S
Sbjct: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGH-------GRQGSGSGQS 2652
Score = 98.6 bits (244), Expect = 8e-21
Identities = 103/370 (27%), Positives = 140/370 (37%), Gaps = 53/370 (14%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 1836 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSS 1895
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G + G++ + G + +LG+ H G + RHG
Sbjct: 1896 SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1955
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGT 170
+ + + S G G W +S G GS GLG GQ + G T
Sbjct: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
Query: 171 PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224
HG + S G + Q + GQ G+G + G QG+ + PG+G + +
Sbjct: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273
+ SGSG SS+ G G S SG S S S + +G SSG
Sbjct: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
Query: 274 SGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333
GS SG SS G GSS S G GS S S HG G G+GH P
Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGS-------RQSSGHGRQGSGSGHSP---SR 2185
Query: 334 GNEARGSGES 343
G GSG S
Sbjct: 2186 GRHGSGSGHS 2195
Score = 98.2 bits (243), Expect = 1e-20
Identities = 101/373 (27%), Positives = 143/373 (38%), Gaps = 35/373 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G SG G+ G++ GHG + S + G+ G+ S S G G E+
Sbjct: 1576 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 1634
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137
G G + G + + + H+ G H Q+ RHG+ + S G
Sbjct: 1635 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQ-- 1691
Query: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196
H S GHG GS G + GLG HG G+ +G S P + G
Sbjct: 1692 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1751
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G G+ A +Q G GS +Q + GS G S++ GS +G S
Sbjct: 1752 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 1804
Query: 257 S-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG---- 311
S G +G ++ SSS G S S G G SG+S S G GS S W SS+G
Sbjct: 1805 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS-SYGQHGSGSGWSSSSGRHGS 1863
Query: 312 -----SSSGNHGGS----------GGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFN 356
S G+H S G G+GH E+ G+ + G G Q+ +S +
Sbjct: 1864 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS-GQSSRGEQHGSSSGSSSS 1922
Query: 357 FDTFWKNFKSKLG 369
+ + LG
Sbjct: 1923 YGQHGSGSRQSLG 1935
Score = 95.9 bits (237), Expect = 5e-20
Identities = 92/333 (27%), Positives = 127/333 (38%), Gaps = 22/333 (6%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G SG G+ G++ GHG + S + G+ G+ S S G G E+
Sbjct: 1106 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 1164
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137
G G + G + + + H+ G H Q+ RHG+ + S G
Sbjct: 1165 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 1221
Query: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196
H S GHG GS G + GLG HG G+ +G S P + G
Sbjct: 1222 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1281
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G G+ A +Q G GS +Q + GS G S++ GS +G S
Sbjct: 1282 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 1334
Query: 257 SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGN 316
S + + + SSG G+ SG S GS S G GS S W SS+G
Sbjct: 1335 SYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394
Query: 317 HGGSGGGNGHK------PGCEKPGNEARGSGES 343
G S G H+ GC + G+ GSG S
Sbjct: 1395 SGQSSGFGHHESSSWQSSGCTQHGS---GSGHS 1424
Score = 95.5 bits (236), Expect = 7e-20
Identities = 106/376 (28%), Positives = 143/376 (38%), Gaps = 52/376 (13%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG-------KAIGKEAGGAAGSKVS 68
GSG G+ +G+ + G HG G S G G ++ G G+ S
Sbjct: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425
Query: 69 EALGQGTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHG 124
G+R + G R G++ + G + +LG+ H G + RHG
Sbjct: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQ--GGLG------------GQGQGNPGGLGT 170
+ + + S G W +S G GS GLG GQ + G T
Sbjct: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
Query: 171 PWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASN 224
HG + S G + Q + GQ G+G + G QG+ + PG+G + +
Sbjct: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSS 273
+ SGSG SS+ GSG S SG S S S + +G SSG
Sbjct: 1606 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1665
Query: 274 SGSSSGGSSGGSSGGSSGNSGGSRGDSGS---ESSWGSSTGSSSG---NHGGSGGGNGHK 327
GS SG SS G GSS S G GS +SS GS SG + G G G GH
Sbjct: 1666 HGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 1725
Query: 328 PGCEKPGNEARGSGES 343
G GSG S
Sbjct: 1726 ---SSHGQHGSGSGRS 1738
Score = 95.1 bits (235), Expect = 9e-20
Identities = 100/341 (29%), Positives = 146/341 (42%), Gaps = 46/341 (13%)
Query: 26 SGEEST----GTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVG 80
SG+ S+ G + G++ HG G S+ G G++ G+ S G G+R++
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPS 2550
Query: 81 TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHN 139
G R G G + + G + G HE Q+ +HG+ + GH
Sbjct: 2551 YG-RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS---------GH- 2599
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSFGMNPQGAPWGQGGN 198
S G+G GS+ G +G+ + G+ +G G+ S S G QG+ GQ +
Sbjct: 2600 -----SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPS 2654
Query: 199 GGPPNFGTNTQGAVAQPGYGSVRASNQ--------NEGCTNPPPSGSGGGSSNSGGGSGS 250
G G + Q G GS R+S++ + SGSG S+ S GSGS
Sbjct: 2655 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGS 2714
Query: 251 -------QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
Q GS+ S+ + GSS+G SSS G S SSG G G G S S
Sbjct: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG--YGRHGAGSGQSLSH 2772
Query: 304 SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
GS +G SS ++G G G+G G + G+ GSG+ G
Sbjct: 2773 GRHGSGSGQSS-SYGQHGSGSGQSSGYSQHGS---GSGQDG 2809
Score = 94.4 bits (233), Expect = 2e-19
Identities = 103/374 (27%), Positives = 141/374 (37%), Gaps = 49/374 (13%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG--KAIGKEAG----GAAGSKVSE 69
GSG G +G+ + G HG G S G G + G+ +G G+ S
Sbjct: 897 GSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSS 956
Query: 70 ALGQGTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIGR---QAEDVIRHGA 125
G+R + Q G++ + G + +LG+ H G + RHG+
Sbjct: 957 YEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1016
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGS--QGGLG------------GQGQGNPGGLGTP 171
+ + S G W +S G GS GLG GQ + G T
Sbjct: 1017 GSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1076
Query: 172 WVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQ 225
HG + S G + Q + GQ G+G + G QG+ + PG+G + ++
Sbjct: 1077 GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 1136
Query: 226 NEGCTNPPPSGSGGGSSNSGGGSG-----------SQSGSSGSGSNGDNNNGSSSGGSSS 274
SGSG SS+ GSG S SG S S S + +G SSG
Sbjct: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
Query: 275 GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334
GS SG SS G GSS S G GS S S HG G G+GH P + G
Sbjct: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGS-------RQSSGHGRQGSGSGHSPSRGRHG 1249
Query: 335 NEARGSGESGIQNS 348
+ S G S
Sbjct: 1250 SGLGHSSSHGQHGS 1263
Score = 94.4 bits (233), Expect = 2e-19
Identities = 97/339 (28%), Positives = 133/339 (39%), Gaps = 17/339 (5%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G SG G+ G++ GHG + S + G+ G+ S S G G E+
Sbjct: 2046 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGPGLGES 2104
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137
G G + G + + + H+ G H Q+ RHG+ + S G
Sbjct: 2105 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ-- 2161
Query: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196
H S GHG GS G + G G HG G+ +G S P + G
Sbjct: 2162 HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS 2221
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G G+ A +Q G GS +Q + GS G S++ GS +G S
Sbjct: 2222 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-------HGSTSGQSSTFDQEGSSTGQSS 2274
Query: 257 S-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG-SSS 314
S G +G ++ SSS G S S G G SG+S S G GS S W SS+G S
Sbjct: 2275 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS-SYGQHGSGSGWSSSSGRHGS 2333
Query: 315 GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
G+ SG G+ + G GSG SG +S G
Sbjct: 2334 GSGQSSGFGHHESSSWQSSGYTQHGSG-SGHSSSYEQHG 2371
Score = 94.0 bits (232), Expect = 2e-19
Identities = 98/344 (28%), Positives = 136/344 (39%), Gaps = 35/344 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G G+
Sbjct: 1914 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS 1971
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G G + LG+R + + G H G + HG
Sbjct: 1972 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSASGQSSS 2028
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 2029 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 2078
Query: 191 APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS----GSGGGSSNSGG 246
+G+ G+G + + G PG G +E + S GSG G S+ G
Sbjct: 2079 PSYGRHGSGSGRSSSSGQHG----PGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2134
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
GS+SG S G +++GSSS GS S SSG GS SRG GS
Sbjct: 2135 QHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS---- 2190
Query: 307 GSSTGSSSGNHG-GSGGGNGHKPGCEKPGNEA-RGSGESGIQNS 348
GS SS G HG GSG + P + G+ + G ESG +S
Sbjct: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS 2234
Score = 93.6 bits (231), Expect = 3e-19
Identities = 108/355 (30%), Positives = 144/355 (40%), Gaps = 31/355 (8%)
Query: 17 GSGEA-GPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGG----AAGSKVSEAL 71
GSG + G Q G S ++ GE G G + S G + +++ G +GS S +
Sbjct: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+G E+ G RQ +G R +GH G ++ R G + G
Sbjct: 544 SRGRHES---GSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES-RSGQSSGYGQ 599
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191
GH+ T G HG Q GQ G + HG + + +G QG+
Sbjct: 600 HGSSSGHSS---THGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQ--QGS 654
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-S 250
GQ + G + Q G GS +S+ + S G S SG SG S
Sbjct: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
Query: 251 QSGSSGSGSNGDNNNGSSSG--------GSSSG-SSSGGSSGGSSGGSSGN--SGGSRGD 299
Q GS S S+G +GS SG GSSSG SSS G G S SSG+ G G
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
Query: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE-SGIQNSETSPG 353
S S GSS+G SS +HG G G C G+ GSG+ SG E+ G
Sbjct: 775 SPSRVRHGSSSGHSS-SHGQHGSGTSCSSSC---GHYESGSGQASGFGQHESGSG 825
Score = 92.4 bits (228), Expect = 6e-19
Identities = 106/385 (27%), Positives = 148/385 (38%), Gaps = 57/385 (14%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G + G HG G S G G+ G+ S
Sbjct: 1706 GSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1765
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119
G G+ G ++ D G+ G+++ H G++ G+Q
Sbjct: 1766 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 1825
Query: 120 VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174
G RG GH+ ++ G + S G G G G G G + W
Sbjct: 1826 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
Query: 175 GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230
GY + +GS G+ GQ G + + + Q G GS ++ + +
Sbjct: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
Query: 231 ---NPPPS----GSGGGSSNSGGGSGSQSG--------SSGSGSNG-----DNNNGSSSG 270
+P PS GSG G S+S G GS SG SGSG + ++ +G SSG
Sbjct: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
Query: 271 GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323
GSSSG SS G +SG SS G G S G S S GS + SSG +G G G
Sbjct: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2061
Query: 324 NGHKPGCEKPGNEARGSGESGIQNS 348
+G PG + G+ +R S G S
Sbjct: 2062 SGQSPGHGQRGSGSRQSPSYGRHGS 2086
Score = 91.7 bits (226), Expect = 1e-18
Identities = 103/379 (27%), Positives = 147/379 (38%), Gaps = 74/379 (19%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---------AIGKEAGGAAGSK 66
GSG G+ + + + G HG S G+ G+ + G+ S
Sbjct: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSP 424
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQ-AEDVIRHGA 125
G G+ ++ +G + GFG + + G V + ++ G HE + + +HG+
Sbjct: 425 GHGQRGSGSGQSPSSG-QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-SAGSF 184
+ GH S GHG GS+ G +G+ G+ +G G+ S S
Sbjct: 484 GS---------GH------SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
Query: 185 GMNPQGAPWGQGGNG--GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS- 241
G + G+ GQ + G G+ + GYGS R+S++ P SGSG S
Sbjct: 529 GHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG-----PYESGSGHSSG 583
Query: 242 -----SNSGGGSG-SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
S SG SG Q GSS S+ +GS+SG SSS G +SG SS SG
Sbjct: 584 LGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGS 643
Query: 296 SR------------------------------GDSGSESSWGSSTGSSSGNHGGSGGGNG 325
S+ G GS S W SS G G+ G G G
Sbjct: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG-PHGSVSGQSSGFG 702
Query: 326 HKPGC-EKPGNEARGSGES 343
HK G + G GSG S
Sbjct: 703 HKSGSGQSSGYSQHGSGSS 721
Score = 91.7 bits (226), Expect = 1e-18
Identities = 107/384 (27%), Positives = 149/384 (38%), Gaps = 55/384 (14%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G + G HG G S G G+ G+ S
Sbjct: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 1295
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
G G+ G ++ D G+ G+++ + G+ G Q+ RHG
Sbjct: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS-SYGHRGSG-SSQSSGYGRHG 1353
Query: 125 ADA----VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVHG- 175
A + RG GH+ ++ G + S G G G G G G + W
Sbjct: 1354 AGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 1413
Query: 176 ---YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-- 230
+ S S G+ GQ G + + + Q G GS ++ + +
Sbjct: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
Query: 231 --NPPPS----GSGGGSSNS----GGGSG-------SQSGSSGSGSNG--DNNNGSSSGG 271
+P PS GSG G S+S G GSG +SGSS S G ++ +G SSG
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY 1533
Query: 272 SSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324
GSSSG SS G +SG SS G G S G S S GS + SSG +G G G+
Sbjct: 1534 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGS 1592
Query: 325 GHKPGCEKPGNEARGSGESGIQNS 348
G PG + G+ +R S G S
Sbjct: 1593 GQSPGHGQRGSGSRQSPSYGRHGS 1616
Score = 91.3 bits (225), Expect = 1e-18
Identities = 104/378 (27%), Positives = 142/378 (37%), Gaps = 59/378 (15%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGH---GLGDALSEGV---GKAIG-KEAGGAAGSKVSE 69
GS G+ +GT+ + GH G G A G G G + G A+G S+
Sbjct: 782 GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
Query: 70 ALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-------------- 115
T + + G + + G + HA G H G
Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG 901
Query: 116 QAEDVIRHGADAVRGSWQGVPGHNGAWETSGGH-GIFGSQGGLGGQGQGN---------- 164
Q+ RHG+ + R S G G + GH G G G G+
Sbjct: 902 QSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHG 961
Query: 165 --PGGLGTPWVHGYPGNSAGSFGMNPQGAPW----GQGGNGG----PPNFGTNTQGAVAQ 214
G HG S+ S+G + G+ GQ G+G P+ G + G+
Sbjct: 962 SRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1021
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274
YG R+ + P SGSG S G G + SG S+G +GSSSG SS+
Sbjct: 1022 SSYGPYRSGSGWSSSRGPYESGSGHSS-----GLGHRESRSGQ-SSGYGQHGSSSGHSST 1075
Query: 275 ----GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
GS+SG SS S G G S G S S GS + SSG +G G G+G PG
Sbjct: 1076 HGQHGSTSGQSS------SCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSGSGQSPGH 1128
Query: 331 EKPGNEARGSGESGIQNS 348
+ G+ +R S G S
Sbjct: 1129 GQRGSGSRQSPSYGRHGS 1146
Score = 90.9 bits (224), Expect = 2e-18
Identities = 105/385 (27%), Positives = 148/385 (38%), Gaps = 57/385 (14%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVG---------KAIGKEAGGAAGSK 66
GSG G +G+ + G HG G S G G+ G+ S
Sbjct: 2176 GSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSS 2235
Query: 67 VSEALGQGTREAVGTGVRQVPGFGAA--DALGNRVGEAA----HALGNT-GHEIGRQAED 119
G G+ G ++ D G+ G+++ H G++ G+Q
Sbjct: 2236 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
Query: 120 VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG----TPWVH- 174
G RG GH+ ++ G + S G G G G G G + W
Sbjct: 2296 ---SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
Query: 175 GYPGNSAGS---FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT- 230
GY + +GS G+ GQ G + + + Q G GS ++ + +
Sbjct: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
Query: 231 ---NPPPS----GSGGGSSNS----GGGSG---------SQSGSSGSGSNGDNNNGSSSG 270
+P PS GSG G S+S G GSG S SG S + ++ +G SSG
Sbjct: 2413 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
Query: 271 GSSSGSSSGGSS-----GGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323
GSSSG SS G +SG SS G G S G S S GS + SSG +G G G
Sbjct: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG-YGRQGSG 2531
Query: 324 NGHKPGCEKPGNEARGSGESGIQNS 348
+G PG + G+ +R S G S
Sbjct: 2532 SGQSPGHGQRGSGSRQSPSYGRHGS 2556
Score = 90.5 bits (223), Expect = 2e-18
Identities = 106/377 (28%), Positives = 155/377 (41%), Gaps = 58/377 (15%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAGGA---AGSKVSE 69
GSG G+ +G+ + HG G S G + + G+ +G + +GS S
Sbjct: 196 GSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSS 255
Query: 70 ALGQ-GTREAVGT-GVRQVPGFGAADALGNRVGEAAHALGNTGHEIG-RQAEDVIRHGAD 126
GQ G+R + G R G++ + G + +LG+ G RQ+ +RHG+
Sbjct: 256 GYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG 315
Query: 127 AVRGSWQGVPGHNGAWETSGGHGIFGS---------QGGLG--------GQGQGNPGGLG 169
+ S G G ++ S GH GS + G G G G G+ G
Sbjct: 316 SGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQG 375
Query: 170 TPWVHGYPGNSAGSFGMNP----QGAPWGQGGNGGPPNFGT--NTQGAVAQPGYGSVRAS 223
HG A S G + Q + +GQ + + G ++ G+ PG+G
Sbjct: 376 Q---HGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQ---- 428
Query: 224 NQNEGCTNPPPSGSGG---GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280
+ G P SG G G S+S G S SG S + ++++ SSG + GS SG
Sbjct: 429 -RGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGH 487
Query: 281 SSG-GSSGGSSGNS------GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333
SSG G G SG S G S G S S GS + S G H G G+G P
Sbjct: 488 SSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG-HSRHGSGSGQSP----- 541
Query: 334 GNEARGSGESGIQNSET 350
+ +RG ESG + S +
Sbjct: 542 -SPSRGRHESGSRQSSS 557
Score = 90.1 bits (222), Expect = 3e-18
Identities = 106/375 (28%), Positives = 141/375 (37%), Gaps = 61/375 (16%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG S+ G G G G G++ G G+ S S G+R + Q
Sbjct: 682 SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741
Query: 86 VPGFGAADALGNRVGEAAHALGN---TGHEIGRQAEDV------IRHGADAVRGSWQGVP 136
G++ L + G+ H G+ +GH GRQ +RHG+ + S G
Sbjct: 742 ---HGSSSGLSSSYGQ--HGSGSHQSSGH--GRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794
Query: 137 GHNGAWETSGGHGIFGSQGGLG------GQGQGNP------GGLGTPWVHGYPGNSAGSF 184
G + +S GH GS G G GQG G + HG + S
Sbjct: 795 GSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSS 854
Query: 185 GMNP----QGAPWGQ---------------GGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225
G + Q + +GQ G+G P G G+ P YG + +
Sbjct: 855 GQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG 914
Query: 226 NEGCTNPPPSGSG-----GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280
+ SGSG G S+SG SG SGSG + S G SS S G
Sbjct: 915 RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHG 974
Query: 281 SSGGSSGGSSGNSGGSR-----GDSGSESSWGSSTGSSSGNHG-GSGGGNGHKPGCEKPG 334
SS GSS + GSR G GS S G S S G HG GSG + + P G
Sbjct: 975 SSSGSSSSYGQHGSGSRQSLGHGQHGSGS--GQSPSPSRGRHGSGSGQSSSYGPYRSGSG 1032
Query: 335 -NEARGSGESGIQNS 348
+ +RG ESG +S
Sbjct: 1033 WSSSRGPYESGSGHS 1047
Score = 88.6 bits (218), Expect = 9e-18
Identities = 93/314 (29%), Positives = 123/314 (39%), Gaps = 14/314 (4%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G SG G+ G++ GHG + S + G+ G+ S S G G E+
Sbjct: 2516 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGES 2574
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGH-EIGRQAEDVIRHGADAVRGSWQGVPG 137
G G + G + + + H+ G H Q+ RHG+ + S G
Sbjct: 2575 SGFGHHESSS-GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ-- 2631
Query: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG-SFGMNPQGAPWGQG 196
H S GHG GS G + GLG HG G+ +G S P + G
Sbjct: 2632 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS 2691
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPS-----GSGGGSSNSGGGSGS 250
G G+ A +Q G GS +Q + G T+ S GS G S+S G GS
Sbjct: 2692 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 2751
Query: 251 QSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG-SRGDSGSESSWGS 308
S SSG G +G + S S G S SS G G SG S G S+ SGS S
Sbjct: 2752 GSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYS 2811
Query: 309 STGSSSGNHGGSGG 322
S + GGS G
Sbjct: 2812 YCKGGSNHDGGSSG 2825
Score = 87.4 bits (215), Expect = 2e-17
Identities = 91/346 (26%), Positives = 134/346 (38%), Gaps = 35/346 (10%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG G+ G++ GHG + S G + G+ G+ S S G G+ ++
Sbjct: 878 SGRGRHGSGSGQSPGHGQRGSGS-GQSPSYGRHGSGSGRSSSSGRHGSGSGQS------- 929
Query: 86 VPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETS 145
GFG + G G H G+ GH + +HG+ + + S G + +S
Sbjct: 930 -SGFGHKSSSGQSSGYTQHGSGS-GHSSSYE-----QHGSRSGQSSRSEQHGSSSGSSSS 982
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG---SFGMNPQGAPWG------QG 196
G GS+ LG G+ G G G+ +G S+G G+ W +
Sbjct: 983 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYES 1042
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNE------GCTNPPPSGSGGGSSNSGGGSG- 249
G+G G + GYG +S+ + G T+ S G ++SG S
Sbjct: 1043 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1102
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309
Q GS S S+G GS SG S G SG S G G G S S GS
Sbjct: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRG--SGSRQSPSYGRHGSGSGRSSSSGQHGSG 1160
Query: 310 TGSSS--GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
G SS G+H S G + + G G+ G ++ ++S G
Sbjct: 1161 LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1206
Score = 86.7 bits (213), Expect = 3e-17
Identities = 95/342 (27%), Positives = 135/342 (39%), Gaps = 31/342 (9%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G+
Sbjct: 974 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGS 1031
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
+ G + G G + LG+R + + G H G + HG
Sbjct: 1032 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQH--GSSSGHSSTHGQHGSTSGQSSS 1088
Query: 136 PGHNGAWE-TSGGHGIFGS----QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
G +GA S HG GS G G QG G+ G HG G+ + Q
Sbjct: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG----HGQRGSGSR------QS 1138
Query: 191 APWGQGGNGG--PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS 248
+G+ G+G + G + G G+G +S+ + GSG G S+ G
Sbjct: 1139 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ--HGSGSGHSSGYGQH 1196
Query: 249 GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGS 308
GS+SG S G +++GSSS GS S SSG GS SRG GS G
Sbjct: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGS----GL 1252
Query: 309 STGSSSGNHG-GSGGGNGHKPGCEKPGNEA-RGSGESGIQNS 348
SS G HG GSG + P + G+ + G ESG +S
Sbjct: 1253 GHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHS 1294
Score = 86.3 bits (212), Expect = 4e-17
Identities = 105/400 (26%), Positives = 162/400 (40%), Gaps = 80/400 (20%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGK--------AIGKEAGGAAGSKVS 68
GSG++ + S+G + G + HG G S G G+ + G+ ++GS S
Sbjct: 224 GSGQSSGFSQHKSSSGQSSGYSQ-HGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS 282
Query: 69 EAL-GQGTREAVGTG------------VRQVPGFGAADALGNRVGEAAHALGNTGHEIGR 115
G G+R+++G G VR G G + + G ++++ +E G
Sbjct: 283 YGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGS 342
Query: 116 --------------QAEDVIRHGADAVRGSWQGVPGH-NGAWETSGGHGIFGSQGGLGGQ 160
Q+ +HG+ + S QG G +G +SG HG Q GQ
Sbjct: 343 GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ 402
Query: 161 ---------GQG-NPGGLGTPWVHGYPGNSAGSFGMNPQ-GAPWGQGGNGGPPNFGTNTQ 209
G+G + G G HG G+ +G + Q G +G+ + GP
Sbjct: 403 HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGP-----YVS 457
Query: 210 GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269
G+ G+G +S+++ + GSG G S+ G GS+SG S G ++ GSSS
Sbjct: 458 GSGYSSGFGHHESSSEHS--SGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSS 515
Query: 270 G----GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS-------WGSSTGSS----- 313
GS S S G S GS G S + R +SGS S +GS SS
Sbjct: 516 SYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYE 575
Query: 314 --SGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351
SG+ G GH+ E ++ G G+ G + +S
Sbjct: 576 SGSGH----SSGLGHQ---ESRSGQSSGYGQHGSSSGHSS 608
Score = 86.3 bits (212), Expect = 4e-17
Identities = 101/369 (27%), Positives = 140/369 (37%), Gaps = 45/369 (12%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GS G+ +G+ ++LGHG G + + G+ G+ S G G+
Sbjct: 2384 GSSSGSSSSYGQHGSGSR--QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS 2441
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALG------NTGHE--------IGRQAEDVI 121
+ G + G G + LG+R + + G ++GH Q+
Sbjct: 2442 GWSSSRGPYE-SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 2500
Query: 122 RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLG-GQGQGNPGGLGTPWVHGYPGNS 180
+HGA + + S G H S G+G GS G G GQ G +P + S
Sbjct: 2501 QHGASSGQSSSHGQ--HGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 2558
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
S G+ G+ G + + +Q G GS +S + GS G
Sbjct: 2559 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ-------HGSRSG 2611
Query: 241 SSNSGGGSGSQSGSS------GSG---SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
S+ G GS SGSS GSG S+G GS SG S S G G SS S G
Sbjct: 2612 QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSS--SHG 2669
Query: 292 NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE--SGIQNSE 349
G G S S + S G SS G G+GH + G+ GSG S Q+
Sbjct: 2670 QHGSGSGRSSSRGPYESRLGHSS-VFGQHESGSGHSSAYSQHGS---GSGHFCSQGQHGS 2725
Query: 350 TSPGMFNFD 358
TS FD
Sbjct: 2726 TSGQSSTFD 2734
Score = 85.1 bits (209), Expect = 1e-16
Identities = 97/343 (28%), Positives = 137/343 (39%), Gaps = 39/343 (11%)
Query: 28 EESTGTNIGEALGH-GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQV 86
+E + T + GH G G + S G G+ G + S+ G G + G +
Sbjct: 1325 QEGSSTGQSSSYGHRGSGSSQSSGYGRH--GAGSGQSPSRGRHGSGSGHSSSYG---QHG 1379
Query: 87 PGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIRHGADAVRGSWQGVPGHNGAWETS 145
G G + + G + + G HE Q+ +HG+ + GH+ ++E
Sbjct: 1380 SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGS---------GHSSSYEQH 1430
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG 205
G S+G G G+ G HG S S G G+ GQ + G
Sbjct: 1431 GSRSGQSSRGERHGSSSGSSSSYGQ---HG--SGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
Query: 206 TNTQGAVAQPGYGSVRASNQNEG---CTNPPPSGSGGGSSNSGGGSG-SQSGSSGSGSNG 261
+ + + + YGS + + G + SG G S SG SG Q GSS S+
Sbjct: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSST 1545
Query: 262 DNNNGSSSGGSSSGSSSGGSSGGSSG------GSSGNSGGSRGDSGSESSWG----SSTG 311
+GS+SG SSS G SSG SS GSS +SG R SGS S G S
Sbjct: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
Query: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSGE-SGIQNSETSPG 353
S ++G G G+G G G GE SG + E+S G
Sbjct: 1606 RQSPSYGRHGSGSGRS---SSSGQHGSGLGESSGFGHHESSSG 1645
Score = 84.7 bits (208), Expect = 1e-16
Identities = 99/362 (27%), Positives = 140/362 (38%), Gaps = 37/362 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GSG + G G+ + G HG G G + G+ G+ S S G G+
Sbjct: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 1395
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
++ G G + + ++ + G + Q+ RHG+ + GS
Sbjct: 1396 GQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS--GSSSSY 1453
Query: 136 PGHNGAWETSGGHGIFGSQGGLG--------GQGQG-----NPGGLGTPWVHG---YPGN 179
H S GHG GS G G G G +P G G+ W Y
Sbjct: 1454 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 1513
Query: 180 SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPSGSG 238
S+ S G+ + + GQ G + Q G S ++S+ + G ++ S G
Sbjct: 1514 SSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 1573
Query: 239 --GGSSNSGGGSGSQ-SGSSGSGSNGDNNNGSSSG------GSSSG-SSSGGSSGGSSGG 288
G S+ G G Q SGS S +G +GS GS SG SSS G G G
Sbjct: 1574 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE 1633
Query: 289 SS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
SS G+ S G S S S GS +G SSG +G G +G E+ G+ +R S G
Sbjct: 1634 SSGFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSRSSSRYGQH 1692
Query: 347 NS 348
S
Sbjct: 1693 GS 1694
Score = 83.6 bits (205), Expect = 3e-16
Identities = 98/362 (27%), Positives = 141/362 (38%), Gaps = 37/362 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GSG + G++ +G+ + G HG G G + G+ G+ S S G G+
Sbjct: 2280 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 2335
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
++ G G + + ++ + G + Q+ RHG+ + GS
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS--GSSSSY 2393
Query: 136 PGHNGAWETSGGHGIFGSQGGLG--------GQGQG-----NPGGLGTPWVHG---YPGN 179
H S GHG GS G G G G +P G G+ W Y
Sbjct: 2394 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG 2453
Query: 180 SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE-GCTNPPPSGSG 238
S S G+ + + GQ G + Q G S ++S+ + G ++ S G
Sbjct: 2454 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 2513
Query: 239 --GGSSNSGGGSGSQ-SGSSGSGSNGDNNNGSSSG------GSSSG-SSSGGSSGGSSGG 288
G S+ G G Q SGS S +G +GS GS SG SSS G G G
Sbjct: 2514 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE 2573
Query: 289 SS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
SS G+ S G S S S GS +G SSG +G G +G E+ G+ + S G
Sbjct: 2574 SSGFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSHYGQH 2632
Query: 347 NS 348
S
Sbjct: 2633 GS 2634
Score = 83.2 bits (204), Expect = 4e-16
Identities = 75/280 (26%), Positives = 112/280 (40%), Gaps = 29/280 (10%)
Query: 64 GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR-QAEDVIR 122
G + S++ R G+G Q P +G G+ G+++ N H G Q+ +
Sbjct: 180 GEQNSDSHQSSGRGQCGSGSGQSPNYGQH---GSGSGQSS---SNDTHGSGSGQSSGFSQ 233
Query: 123 HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182
H + + G G H S G+G GS+ G +G+ + G+
Sbjct: 234 HKSSS--GQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGS------------ 279
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
+ +GQ G+G + G QG+ ++ VR + + ++ GSG S
Sbjct: 280 -------SSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYS 332
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302
S G S SG + ++ +G SSG S GS SG SS GS+ S G GS
Sbjct: 333 YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGS 392
Query: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGC-EKPGNEARGSG 341
S SS G S G H G + PG+ RGSG
Sbjct: 393 SSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSG 432
Score = 82.4 bits (202), Expect = 6e-16
Identities = 100/384 (26%), Positives = 142/384 (36%), Gaps = 62/384 (16%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-------HGLGDALSEGVGKAIGKEAGGAAGSKVSE 69
G G+ G +SG+ S G G + G HG G S G + G +G S
Sbjct: 490 GHGQHGS-RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRH-----GSGSGQSPSP 543
Query: 70 ALGQ---GTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGR--QAEDVIRHG 124
+ G+ G+R++ G G G + + G + H+ G GH+ R Q+ +HG
Sbjct: 544 SRGRHESGSRQSSSYGPHGY-GSGRSSSRGPYESGSGHSSG-LGHQESRSGQSSGYGQHG 601
Query: 125 ADAVRGSWQGVPGHNGAWETS--------------GGHGIFGSQGGLGGQGQGNPGGLGT 170
+ + S G G +S G HG SQ GQ G +
Sbjct: 602 SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPS 661
Query: 171 PWVHGYPGNSAGSFGMNPQGAPW-----------GQGGNGGPPNFGTNTQGAVAQPGYGS 219
HG + S+G + G+ W GQ G + G+ +Q G GS
Sbjct: 662 RGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS-GSGQSSGYSQHGSGS 720
Query: 220 VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS--GSSGSGSN---GDNNNGSSSG---- 270
+S + + SG S G SG S G GSGS+ G GS SG
Sbjct: 721 SHSSGYRKHGSR---SGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPS 777
Query: 271 ----GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326
GSSSG SS GS S + G SG S +G S + G +GH
Sbjct: 778 RVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGH 837
Query: 327 KPGCEKPGNEARGSGESGIQNSET 350
+ G+ + S SG +S +
Sbjct: 838 FSSQGRHGSTSGQSSSSGQHDSSS 861
Score = 82.4 bits (202), Expect = 6e-16
Identities = 97/370 (26%), Positives = 137/370 (37%), Gaps = 53/370 (14%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGT 75
GSG + G++ +G+ + G HG G G + G+ G+ S S G G+
Sbjct: 1810 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGS 1865
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGV 135
++ G G + + ++ + G + Q+ +HG+ + GS
Sbjct: 1866 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS--GSSSSY 1923
Query: 136 PGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG- 194
H S GHG GS G GQ G HG + S+G G+ W
Sbjct: 1924 GQHGSGSRQSLGHGQHGS-----GSGQSPSPSRGR---HGSGSGQSSSYGPYGSGSGWSS 1975
Query: 195 -----QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
+ G+G G + GYG +S+ + S SG SS G+
Sbjct: 1976 SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS 2035
Query: 250 S-------QSGSSGSGSNGDNNNGSSSG---------------------GSSSG-SSSGG 280
S Q GS S S+G GS SG GS SG SSS G
Sbjct: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG 2095
Query: 281 SSGGSSGGSS--GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEAR 338
G G SS G+ S G S S S GS +G SSG +G G +G E+ G+ +
Sbjct: 2096 QHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSG 2154
Query: 339 GSGESGIQNS 348
S G S
Sbjct: 2155 SSSRYGQHGS 2164
Score = 80.9 bits (198), Expect = 2e-15
Identities = 96/352 (27%), Positives = 136/352 (38%), Gaps = 45/352 (12%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
GSG + + G++ +G+ + G D G + G+ G+ S + G +
Sbjct: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGSDF---GHSSSYGQHGSGSGWSSSNGPHGSVSG 696
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
++ GFG G G + H G++ H G + +HG+ + + S
Sbjct: 697 QS--------SGFGHKSGSGQSSGYSQHGSGSS-HSSGYR-----KHGSRSGQSSRSEQH 742
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWG- 194
G + +S G GS G QG+ G V HG + S G + G
Sbjct: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802
Query: 195 -----QGGNGGPPNFGTNTQGA---VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
+ G+G FG + G+ +Q G S S+Q GS G S+S G
Sbjct: 803 SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGR-------HGSTSGQSSSSG 855
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
S SG S S ++ + +SG GS SG S G GS S G GS
Sbjct: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGS---- 911
Query: 307 GSSTGSSSGNHGGSGGGN----GHKPGC-EKPGNEARGSGESGIQNSETSPG 353
GS SSSG H GSG G GHK + G GSG SG +S G
Sbjct: 912 GSGRSSSSGRH-GSGSGQSSGFGHKSSSGQSSGYTQHGSG-SGHSSSYEQHG 961
Score = 74.7 bits (182), Expect = 1e-13
Identities = 57/170 (33%), Positives = 74/170 (43%), Gaps = 16/170 (9%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
GQ + G N ++ Q G GS ++ N + GSG G S+S GS SG
Sbjct: 174 GQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQ-------HGSGSGQSSSNDTHGSGSG 226
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSG----GSSGGSSGNSGGSRGDSGSESSWG-- 307
S S +++G SSG S GS SG SSG GS G S R SGS SS+G
Sbjct: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQH 286
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNF 357
S S HG G G+ P + G+ GSG S S +++
Sbjct: 287 GSGSRQSLGHGRQGSGSRQSPSHVRHGS---GSGHSSSHGQHGSGSSYSY 333
Score = 67.0 bits (162), Expect = 3e-11
Identities = 87/331 (26%), Positives = 128/331 (38%), Gaps = 58/331 (17%)
Query: 47 LSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAA--H 104
L + K IGK+ +GSK+ + Q E T + N+ E++ H
Sbjct: 81 LVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEE-----------NKRQESSFSH 129
Query: 105 ALGNTGHE--IGRQAEDVIRHGADAV--RGSWQ-GVPGHNGAWETSGGHGIFGSQGGLGG 159
+ + G R ++ G +++ R S+Q G + ++ SG +G Q
Sbjct: 130 SSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSY--SGQSSSYGEQNSDSH 187
Query: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGS 219
Q G G G+ +G Q +GQ G+G + +T G+ + G
Sbjct: 188 QSSGR----------GQCGSGSG------QSPNYGQHGSGSGQSSSNDTHGSGSGQSSGF 231
Query: 220 VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG 279
+ + + + GSG G S+ G GS+SG S G +++GSSS GS S
Sbjct: 232 SQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSR 291
Query: 280 GSSG-GSSG------------GSSGNSGGSRGDSGSESSWGSSTG---SSSGNHGGSG-- 321
S G G G GS S G GS SS+ S G S SG G G
Sbjct: 292 QSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQH 351
Query: 322 -GGNGHKPGCEKPGNEARGSGESGIQNSETS 351
G+G G K G+ GSG S Q S
Sbjct: 352 ESGSGQSSGYSKHGS---GSGHSSSQGQHGS 379
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/166 (31%), Positives = 66/166 (39%), Gaps = 13/166 (7%)
Query: 193 WGQGGNGGPPNFGTNTQGAVAQPGYGSV--RASNQNE--GCTNPPPSGSGG-GSSNSGGG 247
W G N ++ N +G++ +PG S+ R S Q + G N S G NS
Sbjct: 132 WSAGEND---SYSRNVRGSL-KPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSH 187
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307
S G GSGS N G GS SG SS + GS G S SG S+ S S S G
Sbjct: 188 QSSGRGQCGSGSGQSPNYGQH--GSGSGQSSSNDTHGSGSGQS--SGFSQHKSSSGQSSG 243
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
S S H G +G + G G R S S + G
Sbjct: 244 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSG 289
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 103 bits (256), Expect = 3e-22
Identities = 70/196 (35%), Positives = 75/196 (38%), Gaps = 45/196 (22%)
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG 205
GG F S G G G G GG G + G G S GS+G GG+GG
Sbjct: 460 GGQEDFESSGA-GKIGLGGRGGSGGSYGRGSRGGSGGSYG---------GGGSGG----- 504
Query: 206 TNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN 265
G GGGS + GG GS G SGSG
Sbjct: 505 ------------------------------GYGGGSGSRGGSGGSYGGGSGSGGGSGGGY 534
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
G SGG SG S GG SGGS G G SG G G S G S G+HGG G G
Sbjct: 535 GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGG 594
Query: 326 HKPGCEKPGNEARGSG 341
G G EA GSG
Sbjct: 595 ESGGSYGGGEEASGSG 610
Score = 85.9 bits (211), Expect = 6e-17
Identities = 52/113 (46%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Query: 235 SGSGG-GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
SG+G G GG GS S GS G G S GG GS S G SGGS GG SG+
Sbjct: 468 SGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSG 527
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGG--GNGHKPGCEKPGNEARGSGESG 344
GGS G G S G S GS G+ GGSGG G G G G GSG G
Sbjct: 528 GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRG 580
Score = 82.4 bits (202), Expect = 6e-16
Identities = 65/182 (35%), Positives = 79/182 (43%), Gaps = 14/182 (7%)
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
+++ G + S G G G + G +G GS+GG GG G G G G G
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGR-GSRGGSGGSYGGGGSGGGYGGGSGSRG 514
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
S GS+G G+ G GG G + G ++ G+ G G S N G GSG
Sbjct: 515 GSGGSYG-GGSGSGGGSGGGYGGGSGGGHSGGS----GGGHSGGSGGNYG------GGSG 563
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
G SGGG G SGS G GS G + GS GG S GS GG SGG G G
Sbjct: 564 SGG-GSGGGYGGGSGSRG-GSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
Query: 299 DS 300
S
Sbjct: 622 HS 623
Score = 75.9 bits (185), Expect = 6e-14
Identities = 48/121 (39%), Positives = 57/121 (47%), Gaps = 15/121 (12%)
Query: 236 GSGGGSSNSGGGS-GSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS-----------G 283
G GG + G GS G GS G G +G G S SG S GG S G
Sbjct: 477 GRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGG 536
Query: 284 GSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
GS GG SG SGG GS ++G +GS G+ GG GGG+G + G G+ GSG
Sbjct: 537 GSGGGHSGGSGGGH-SGGSGGNYGGGSGSGGGSGGGYGGGSGSRGG--SGGSHGGGSGFG 593
Query: 344 G 344
G
Sbjct: 594 G 594
Score = 71.6 bits (174), Expect = 1e-12
Identities = 56/154 (36%), Positives = 65/154 (42%), Gaps = 25/154 (16%)
Query: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG----SSNSGGGSGS 250
+ G GG G+ GS+R+S + G GGG SS GGGS
Sbjct: 13 RSGGGGGGGLGSG----------GSIRSSYSRFSSSG---GGGGGGRFSSSSGYGGGSSR 59
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS------SGGSSGNSGGSRG--DSGS 302
G G GS G + G S GG S+ S GG GGS SGG +SGG G GS
Sbjct: 60 VCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGS 119
Query: 303 ESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNE 336
+G GS G GG GGG G G NE
Sbjct: 120 GGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANE 153
Score = 68.2 bits (165), Expect = 1e-11
Identities = 51/121 (42%), Positives = 52/121 (42%), Gaps = 12/121 (9%)
Query: 236 GSGGG---------SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
GSGG SS GGG G S SSG G G GGS S GGS GG S
Sbjct: 23 GSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFS 82
Query: 287 GGSSGNS--GGSRGDSG-SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
S G GGSRG G S + SS G G GGSGGG G G G G G
Sbjct: 83 ASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAG 142
Query: 344 G 344
G
Sbjct: 143 G 143
Score = 63.5 bits (153), Expect = 3e-10
Identities = 41/97 (42%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSGGSRGDSGSESSWGS 308
+ G S+G G G S GS GS GGS G G G+ GG G SGS G
Sbjct: 459 EGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518
Query: 309 STGSSSGNHGGSGGGNGHKPGCEKPGNEARG-SGESG 344
S G SG+ GGSGGG G G G G SG SG
Sbjct: 519 SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSG 555
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/114 (40%), Positives = 49/114 (42%), Gaps = 11/114 (9%)
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG--SSSGGSSGGSS-------GGSSGN 292
S SGGG G GS GS + + SS GG G SSS G GGSS GGS G
Sbjct: 12 SRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71
Query: 293 S--GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
S GGS G + S G G S G G SGGG G G G G
Sbjct: 72 SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGG 125
Score = 55.5 bits (132), Expect = 8e-08
Identities = 50/171 (29%), Positives = 60/171 (35%), Gaps = 50/171 (29%)
Query: 127 AVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQ-----GQGNPGGLGTPWVHGYPGNSA 181
++R S+ G GG G F S G GG G+G G G + Y G S
Sbjct: 27 SIRSSYSRFSSSGGG----GGGGRFSSSSGYGGGSSRVCGRGGGGSFG----YSYGGGSG 78
Query: 182 GSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G F + G +G G G FG SGGG
Sbjct: 79 GGFSASSLGGGFGGGSRG----FG-----------------------------GASGGGY 105
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
S+SGG G G SG G G G SG G GG+ GG G + N
Sbjct: 106 SSSGGFGGGFGGGSGGGFGG----GYGSGFGGFGGFGGGAGGGDGGILTAN 152
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/108 (37%), Positives = 45/108 (41%), Gaps = 15/108 (13%)
Query: 252 SGSSGSGSNGDNNNGSSSGG------SSSGSSSGGSSGGSSGGSSGNSGGS-----RGDS 300
S S S S G G SGG S SS GG GG SSG GGS RG
Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Query: 301 GSES-SWGSSTG---SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
GS S+G +G S+S GG GGG+ G G + G G
Sbjct: 67 GSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGG 114
Score = 37.0 bits (84), Expect = 0.030
Identities = 36/132 (27%), Positives = 51/132 (38%), Gaps = 3/132 (2%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99
G G G ++ + GG G + S + G G + G FG + G+
Sbjct: 21 GLGSGGSIRSSYSR-FSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79
Query: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGI-FGSQGGLG 158
G +A +LG G G + G + G + G G GG+G FG GG G
Sbjct: 80 GFSASSLGG-GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFG 138
Query: 159 GQGQGNPGGLGT 170
G G GG+ T
Sbjct: 139 GGAGGGDGGILT 150
Score = 37.0 bits (84), Expect = 0.030
Identities = 37/141 (26%), Positives = 45/141 (31%), Gaps = 17/141 (12%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREA 78
G G G G G G G + G G G G GS + G G +
Sbjct: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHS 551
Query: 79 VGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGH 138
G+G G G+ G G G +G R G+ G G G
Sbjct: 552 GGSGGNYGGGSGSGGGSGGGYG------GGSGS----------RGGSGGSHGGGSGFGGE 595
Query: 139 NGAWETSGGHGIFGSQGGLGG 159
+G GG GS GG GG
Sbjct: 596 SGG-SYGGGEEASGSGGGYGG 615
Score = 35.0 bits (79), Expect = 0.11
Identities = 30/79 (37%), Positives = 31/79 (39%), Gaps = 5/79 (6%)
Query: 272 SSSGSSSGGSSGGSSG-GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS----GGGNGH 326
SS S SGG GG G G S S SR S G SSSG GGS G G G
Sbjct: 8 SSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGG 67
Query: 327 KPGCEKPGNEARGSGESGI 345
G G G S +
Sbjct: 68 SFGYSYGGGSGGGFSASSL 86
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 101 bits (252), Expect = 1e-21
Identities = 91/249 (36%), Positives = 100/249 (40%), Gaps = 52/249 (20%)
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQG 196
G G GG G FG GG GG G+ G G GY G G G G G
Sbjct: 23 GGGGGGSGGGGCGFFGG-GGSGGGSSGS--GCGYSGGGGYSGGGCG-------GGSSGGG 72
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG----GGSSNSGGGSGSQS 252
G GG G + G+V G G +S GC + GSG GG +SGGGSG S
Sbjct: 73 GGGGIGGCGGGSGGSVKYSGGGG--SSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFS 130
Query: 253 GSSGSGSNGDNNNGSSSGGSSSG------SSSGGSSGGSSGGSSG--NSGGSRGD----- 299
G S G + SS GG SG S G SSGGSSGG SG +SGG G
Sbjct: 131 SGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYS 190
Query: 300 -SGSESSWGSSTGSSSG------------------NHGGSGGGNGHKPGCEKP----GNE 336
GS GSS GS SG G SGGG GC G+
Sbjct: 191 GGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSS 250
Query: 337 ARGSGESGI 345
G G SGI
Sbjct: 251 GCGGGSSGI 259
Score = 93.6 bits (231), Expect = 3e-19
Identities = 88/268 (32%), Positives = 104/268 (38%), Gaps = 29/268 (10%)
Query: 89 FGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGH 148
FG + G G G G+ G G G G G G+ + SGG
Sbjct: 37 FGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGG--GSGGSVKYSGGG 94
Query: 149 GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN- 207
G G G G G G + G G+S G G G GG G + G
Sbjct: 95 GSSGGGSGCFSSGGGGSGCFSS----GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150
Query: 208 -TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS--SNSGGGSGSQSGSSGSGSNGDNN 264
+ AV YG V + + G + SG GGGS SGGGSG GSSG +G +
Sbjct: 151 FSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVS 210
Query: 265 N-----------GSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
+ S GGSS G SGGS SSGG G+SG G SG S S G S
Sbjct: 211 SQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS 270
Query: 314 SGNHGGSGGGNGHKPGCEKPGNEARGSG 341
G SGGG G G+ GSG
Sbjct: 271 VCGGGSSGGGGG--------GSSVGGSG 290
Score = 92.4 bits (228), Expect = 6e-19
Identities = 79/238 (33%), Positives = 95/238 (39%), Gaps = 26/238 (10%)
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLGGQ-----GQGNPGGLGTPWVHGYPGN---SA 181
G + G G+ GG GI G GG GG G G+ GG + G G+ S+
Sbjct: 57 GGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSS 116
Query: 182 GSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G G + G+ G GG G+ + G G ++ SG G G
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGC 176
Query: 242 SNSGGGSGSQSGSSGSGSN--GDNNNGSSSGGSSS----------------GSSSGGSSG 283
+SGGG GS G SG GS G ++ GS SG SS GSS GG SG
Sbjct: 177 FSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSG 236
Query: 284 GSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSG 341
GS SSG GGS G G S GS S G GG +G G G G G
Sbjct: 237 GSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 85.5 bits (210), Expect = 7e-17
Identities = 55/132 (41%), Positives = 59/132 (44%), Gaps = 13/132 (9%)
Query: 229 CTNPPPSGSGGGSSNSGG-----GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG 283
C G GGG S GG G GS GSSGSG G + G SGG G SSGG G
Sbjct: 16 CVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGC-GYSGGGGYSGGGCGGGSSGGGGG 74
Query: 284 GSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS-------GGGNGHKPGCEKPGNE 336
G GG G SGGS SG S G +G S GGS GG +G GC G
Sbjct: 75 GGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGG 134
Query: 337 ARGSGESGIQNS 348
G SG +S
Sbjct: 135 GSSGGGSGCFSS 146
Score = 85.5 bits (210), Expect = 7e-17
Identities = 77/207 (37%), Positives = 85/207 (41%), Gaps = 27/207 (13%)
Query: 143 ETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPP 202
+TSGG G GG GG G G GG G G G+ G G GG
Sbjct: 18 KTSGGGG---GGGGSGGGGCGFFGG--------------GGSGGGSSGSGCGYSGGGGYS 60
Query: 203 NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGD 262
G G+ G G + G + SGGG S+ GG SG GSG
Sbjct: 61 GGGCG-GGSSGGGGGGGIGGCGGGSGGS---VKYSGGGGSSGGGSGCFSSGGGGSGCFSS 116
Query: 263 NNNGSSSGGSSSGSS-SGGSSGGSSGGSSGNSGGSRGDSGSESSWG--SSTGSSSGNHG- 318
GSS GGS SS GGSSGG SG S GG G + S+G SS GSS G G
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGC 176
Query: 319 -GSGGGNGHKPGCEKPGNEARGSGESG 344
SGGG G G G G G SG
Sbjct: 177 FSSGGGGGSVCG-YSGGGSGCGGGSSG 202
Score = 83.6 bits (205), Expect = 3e-16
Identities = 90/281 (32%), Positives = 108/281 (38%), Gaps = 29/281 (10%)
Query: 40 GHGLGDALSEGVGKAI---GKEAGGAAGSKVSEALGQG-TREAVGTGVRQVPGFGAADAL 95
G G G S G G G GG++GS + G G + G G G G
Sbjct: 21 GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC 80
Query: 96 GNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQG 155
G G + G G G G + G G G + GG G F S G
Sbjct: 81 GGGSGGSVKYSGGGGSSGGGS-------GCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133
Query: 156 GL---GGQGQGNPGGLG----TPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNF--GT 206
G GG G + GG G Y G S+G G GG G + G
Sbjct: 134 GGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGG 193
Query: 207 NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-----SQSGSSGSGSNG 261
+ G + G GS S+Q T+ P S GG S+ GGGSG S G GS G
Sbjct: 194 SGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCG 253
Query: 262 DNNNGSSSGGSSSGSSS---GGSSGGSSGGSS-GNSGGSRG 298
++G SG SG S GGSSGG GGSS G SG +G
Sbjct: 254 GGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 77.4 bits (189), Expect = 2e-14
Identities = 64/167 (38%), Positives = 70/167 (41%), Gaps = 27/167 (16%)
Query: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG----GGSGSQSGSSGSGSNGDNNN-- 265
V G G + GC GSGGGSS SG GG G G G GS+G
Sbjct: 17 VKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGG 76
Query: 266 ----GSSSGGSSSGSSSGGSSGG-----SSGG------SSGNSGGSRGDSGSESSWGSST 310
G SGGS S GGSSGG SSGG SSG G S G SG SS G
Sbjct: 77 IGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGG-- 134
Query: 311 GSSSGNHG----GSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
GSS G G G GG +G C+ G + G G +S G
Sbjct: 135 GSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGG 181
Score = 37.4 bits (85), Expect = 0.023
Identities = 62/247 (25%), Positives = 79/247 (31%), Gaps = 70/247 (28%)
Query: 15 CLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEG---VGKAIGKEAGGAAGSKVSEAL 71
C SG G G + G + G G G S G G+A+ ++ G S S
Sbjct: 113 CFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGG 172
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
G G + G G V G+ G+ G + +G+ +Q S
Sbjct: 173 GSGCFSSGGGG-GSVCGYSGG---GSGCGGGSSGGSGSGYVSSQQVTQT----------S 218
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191
P + G +SGG GG GG G + GG G
Sbjct: 219 CAPQPSYGGG--SSGG-------GGSGGSGCFSSGGGG---------------------- 247
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ 251
G G GG G GS GC GG S+ GGG GS
Sbjct: 248 --GSSGCGG------------GSSGIGS--------GCIISGGGSVCGGGSSGGGGGGSS 285
Query: 252 SGSSGSG 258
G SGSG
Sbjct: 286 VGGSGSG 292
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 91.3 bits (225), Expect = 1e-18
Identities = 73/226 (32%), Positives = 95/226 (42%), Gaps = 28/226 (12%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203
++GG+G S GQ PG P P +++GS+G + Q + +GQ P
Sbjct: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251
G+ +Q QP YG + S + NPP S SGGG GGG+ Q
Sbjct: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
Query: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
S SSG GS G N SGG SG GG G SG GG G + SS G
Sbjct: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
Query: 312 SSSGNHGGSGG-GNGHKPGCEK-PGNEARGSGESGIQNSETSPGMF 355
G GG GG G + G K G +GS Q++ + +F
Sbjct: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIF 288
Score = 66.2 bits (160), Expect = 5e-11
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
G G GG+G+G P G G GY G +G G G P G GG GG G
Sbjct: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427
Query: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269
P ++ S +NE C P P G GGG G G G G G + G
Sbjct: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485
Query: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
G G GG GG GG G G + DS E
Sbjct: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516
Score = 56.6 bits (135), Expect = 4e-08
Identities = 67/278 (24%), Positives = 97/278 (34%), Gaps = 39/278 (14%)
Query: 29 ESTGTN-IGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVP 87
+ST T+ G++ G + + G G + G+ G S Q ++ + G P
Sbjct: 43 QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSS---QSSQSSYGQQ-SSYP 98
Query: 88 GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGG 147
G+G A + G + ++ + GS+ P + G ++ G
Sbjct: 99 GYGQQPAPSSTSGSYGSSSQSSSY-------------GQPQSGSYSQQPSYGGQQQSYGQ 145
Query: 148 HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN 207
+ G G Q Q N G G G G++G + G G GG N +
Sbjct: 146 QQSYNPPQGYGQQNQYNSSSGG-----GGGGGGGGNYGQDQSSMSSGGGSGGGYGN--QD 198
Query: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267
G GYG + G GSGGG GGG G S G G G
Sbjct: 199 QSGGGGSGGYGQQDRGGRGRG-------GSGGGG--GGGGGGYNRSSGGYEPRG---RGG 246
Query: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
GG G G GG + GSR DS ++S
Sbjct: 247 GRGG--RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282
Score = 52.8 bits (125), Expect = 5e-07
Identities = 52/175 (29%), Positives = 67/175 (38%), Gaps = 17/175 (9%)
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG-----GGSSNSGG 246
P+GQ G T+T G Q Y S S T P G G G S +S
Sbjct: 32 PYGQQSYSGYSQ-STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQS 89
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304
G QS G G + S+SG SSS SSS G S + GG + G +
Sbjct: 90 SYGQQSSYPGYGQQPAPS--STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ 147
Query: 305 S------WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
S +G +S + GG GGG G G ++ + G G N + S G
Sbjct: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGG 202
Score = 49.3 bits (116), Expect = 6e-06
Identities = 51/161 (31%), Positives = 66/161 (40%), Gaps = 16/161 (9%)
Query: 206 TNTQGAV-AQPGYGSVRASNQNEG-------CTNPPPSGSGGGSSNSGG-----GSGSQS 252
T + GA QPG G + S+Q G + SG G S +S G G G+QS
Sbjct: 11 TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGS 312
G GS G + SS S SS G SS + GS G S SS+G S
Sbjct: 71 TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSSYGQPQ-S 127
Query: 313 SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
S + S GG G ++ N +G G+ NS + G
Sbjct: 128 GSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168
Score = 45.8 bits (107), Expect = 6e-05
Identities = 38/140 (27%), Positives = 48/140 (34%), Gaps = 14/140 (10%)
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
GGNG G G + + GYG + G GG S GGG G Q
Sbjct: 379 GGNG---RGGRGRGGPMGRGGYGGGGSGG----------GGRGGFPSGGGGGGGQQRAGD 425
Query: 256 GSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS-GGSRGDSGSESSWGSSTGSSS 314
N N + S + G GG G+ GG+ GD G G
Sbjct: 426 WKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYR 485
Query: 315 GNHGGSGGGNGHKPGCEKPG 334
G G GG G + G ++ G
Sbjct: 486 GRGGDRGGFRGGRGGGDRGG 505
Score = 43.5 bits (101), Expect = 3e-04
Identities = 79/359 (22%), Positives = 110/359 (30%), Gaps = 69/359 (19%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99
G+G + + G G GG G S ++ G G G + G G + G +
Sbjct: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211
Query: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159
G +G G G G +G +E G G G +GG+GG
Sbjct: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256
Query: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209
+G G P G +S N G G N + TN +
Sbjct: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316
Query: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247
+ R + + +G + PPS G SG
Sbjct: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302
G +G G G G G GG S G GG SGG GG +G + +
Sbjct: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
Query: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQ 346
SW + G G G GGN G + G ++ G RG G +
Sbjct: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495
Score = 42.7 bits (99), Expect = 5e-04
Identities = 83/381 (21%), Positives = 120/381 (31%), Gaps = 51/381 (13%)
Query: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQ---- 73
+G G QS + S G G+G A S G + G S + Q
Sbjct: 78 TGGYGSSQSSQSSYGQQSSYP-GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136
Query: 74 -GTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130
G +++ G P G+G + + G G G G+ + G
Sbjct: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGG------ 188
Query: 131 SWQGVPGHNGAWETSGGHGIFG-SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G G G + SGG G G Q GG+G+G GG G GY +S G
Sbjct: 189 ---GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-- 247
G G+GG GG G N G G R ++ + N G G + +
Sbjct: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQG---SRHDSEQDNSDNNTIFVQGLGENVTIESVA 302
Query: 248 ----------SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN--SGG 295
+ ++G D G G ++ S+ + G SG
Sbjct: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362
Query: 296 -------------SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342
+RG G G +GG G G G + G G G
Sbjct: 363 PIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR 422
Query: 343 SGIQNSETSPGMFNFDTFWKN 363
+G +P N + W+N
Sbjct: 423 AGDWKC-PNPTCENMNFSWRN 442
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 91.3 bits (225), Expect = 1e-18
Identities = 56/131 (42%), Positives = 63/131 (48%), Gaps = 12/131 (9%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G+G +GG G + G GYG + + G G GGG S GG G G
Sbjct: 455 GEGSSGGGGRGGGSFGG-----GYGGGSSGGGSSG------GGHGGGHGGSSGG-GYGGG 502
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
SSG GS+G G SS G GSSSGG GGSSGG G GG GS S G GSS
Sbjct: 503 SSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSS 562
Query: 314 SGNHGGSGGGN 324
SG H S G+
Sbjct: 563 SGGHKSSSSGS 573
Score = 90.5 bits (223), Expect = 2e-18
Identities = 54/129 (41%), Positives = 64/129 (49%), Gaps = 8/129 (6%)
Query: 227 EGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGG-- 284
EG + G GGGS G G GS G S G +G + GSS GG GSS GGSSGG
Sbjct: 454 EGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513
Query: 285 ----SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGS 340
SSGG G+S G G S G G SSG GGS G G+ G G+++ S
Sbjct: 514 GGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSG--GGSSSGGGYGGGSSSGGHKSSSS 571
Query: 341 GESGIQNSE 349
G G +S+
Sbjct: 572 GSVGESSSK 580
Score = 77.8 bits (190), Expect = 2e-14
Identities = 60/163 (36%), Positives = 68/163 (41%), Gaps = 41/163 (25%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
GS GG GG+G G+ GG GY G S+G G + G G GG+ G
Sbjct: 457 GSSGG-GGRGGGSFGG-------GYGGGSSGG-GSSGGGHGGGHGGSSGG---------- 497
Query: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
GYG SGGGSS G G GS SG G S+G GSS GG
Sbjct: 498 ----GYGG---------------GSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGG 538
Query: 272 SSS---GSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
GSS GGSS G G +SGG + S SS G
Sbjct: 539 GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581
Score = 77.8 bits (190), Expect = 2e-14
Identities = 60/162 (37%), Positives = 72/162 (44%), Gaps = 41/162 (25%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203
+SGG G G G GG G G+ GG G+S G G GG+GG
Sbjct: 458 SSGGGGRGGGSFG-GGYGGGSSGG----------GSSGGGHG----------GGHGGS-- 494
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDN 263
+ GYG + + G G GG S+SGG GS SG G GS+G
Sbjct: 495 ---------SGGGYGGGSSGGGSSG-------GGYGGGSSSGGHGGSSSGGYGGGSSGGG 538
Query: 264 NNGSSSGGSSSGSSSGGSSGG--SSGGSSGNSGGSRGDSGSE 303
G G S GSSSGG GG SSGG +S GS G+S S+
Sbjct: 539 GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580
Score = 73.6 bits (179), Expect = 3e-13
Identities = 56/131 (42%), Positives = 62/131 (47%), Gaps = 8/131 (6%)
Query: 219 SVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS 278
SVR S+ ++ G GGG GGG S SS GS G G SSGG S GS S
Sbjct: 2 SVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLG---GGFSSGGFSGGSFS 58
Query: 279 GGSSGGSS-GGSSGNSGGSRGDSGS--ESSWGSST--GSSSGNHGGSGGGNGHKPGCEKP 333
GSSGG GGSSG GG G G S+GSS+ GS G+ GG G G G
Sbjct: 59 RGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFG 118
Query: 334 GNEARGSGESG 344
G G G G
Sbjct: 119 GGGFGGGGFGG 129
Score = 71.2 bits (173), Expect = 1e-12
Identities = 58/150 (38%), Positives = 67/150 (44%), Gaps = 17/150 (11%)
Query: 235 SGSGGGSSNSGGGSG-------SQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
SG GGG GGG G S GS G G S+G + GS S GSS G GGSSGG
Sbjct: 16 SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGG-Y 74
Query: 287 GGSSGNSGGS-RGDSGSESSWGSSTGSSSGNH-------GGSGGGNGHKPGCEKPGNEAR 338
GG G GGS RG GS S GS GS G GGS GG G G G
Sbjct: 75 GGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGG 134
Query: 339 GSGESGIQNSETSPGMFNFDTFWKNFKSKL 368
G+ G+ + M N + ++ K+
Sbjct: 135 FGGDGGLLSGNEKVTMQNLNDRLASYLDKV 164
Score = 59.3 bits (142), Expect = 6e-09
Identities = 45/132 (34%), Positives = 50/132 (37%), Gaps = 9/132 (6%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G GG GG G GS+ + G + S G GG SG G
Sbjct: 17 GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG 76
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
G G G S GS SS GGS GGS GG G+ GG GS G G
Sbjct: 77 LGGFG-------GGSFRGSYGSSSFGGSYGGSFGG--GSFGGGSFGGGSFGGGGFGGGGF 127
Query: 314 SGNHGGSGGGNG 325
G GG GG+G
Sbjct: 128 GGGFGGGFGGDG 139
Score = 45.8 bits (107), Expect = 6e-05
Identities = 43/145 (29%), Positives = 55/145 (37%), Gaps = 20/145 (13%)
Query: 153 SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNP-QGAPWGQGGNGGPPNFGTNT-QG 210
S GG GG G G GG+ + + G+ G F G + +G +GG G++ G
Sbjct: 16 SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYG 75
Query: 211 AVAQPGYGSVRASNQNEGCTNPPPSGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGS 267
+ G GS R S + GGGS + GGGS G
Sbjct: 76 GLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGS---------------FGGG 120
Query: 268 SSGGSSSGSSSGGSSGGSSGGSSGN 292
GG G GG GG G SGN
Sbjct: 121 GFGGGGFGGGFGGGFGGDGGLLSGN 145
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/76 (40%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 280 GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGG--NGHKPGCEKPGNEA 337
GSSGG G G+ GG G G S GSS G G HGGS GG G G G
Sbjct: 457 GSSGGG-GRGGGSFGGGYG--GGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513
Query: 338 RGSGESGIQNSETSPG 353
G SG +S G
Sbjct: 514 GGGSSSGGHGGSSSGG 529
Score = 42.4 bits (98), Expect = 7e-04
Identities = 36/124 (29%), Positives = 45/124 (36%), Gaps = 46/124 (37%)
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQG 196
G +G + GG+G S GG GG G GY G S+G G G
Sbjct: 502 GSSGGGSSGGGYGGGSSSGGHGGSSSG-----------GYGGGSSGG----------GGG 540
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G GG + G ++ G G GG S+SGG S SGS G
Sbjct: 541 GYGGGSSGGGSSSG-------------------------GGYGGGSSSGGHKSSSSGSVG 575
Query: 257 SGSN 260
S+
Sbjct: 576 ESSS 579
Score = 39.3 bits (90), Expect = 0.006
Identities = 44/156 (28%), Positives = 60/156 (38%), Gaps = 24/156 (15%)
Query: 46 ALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHA 105
+L EG G + G GG G G G+ +G G G + G G +
Sbjct: 451 SLLEGEGSSGG---GGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSS--GGGYGGGSSG 505
Query: 106 LGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP 165
G++G G GS G GH G+ +SGG+G GS GG GG G
Sbjct: 506 GGSSGGGYGG--------------GSSSG--GHGGS--SSGGYG-GGSSGGGGGGYGGGS 546
Query: 166 GGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGP 201
G G+ GY G S+ + G+ + GP
Sbjct: 547 SGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGP 582
Score = 36.6 bits (83), Expect = 0.039
Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 22/107 (20%)
Query: 145 SGGHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNS-AGSFGMNPQGAPWGQGGNGGPP 202
SGG GS GG G G GGLG G+ G S GS+G + G +G GG
Sbjct: 53 SGGSFSRGSSGGGCFGGSSGGYGGLG-----GFGGGSFRGSYGSSSFGGSYGGSFGGGSF 107
Query: 203 NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
G+ G+ G+G G GGG GG G
Sbjct: 108 GGGSFGGGSFGGGGFGG---------------GGFGGGFGGGFGGDG 139
Score = 35.0 bits (79), Expect = 0.11
Identities = 31/100 (31%), Positives = 37/100 (37%), Gaps = 4/100 (4%)
Query: 272 SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG--SSSGNHGGSGGGNGHKPG 329
SSS S SGG GG GG SS GS G SS G GGS G
Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGG 65
Query: 330 CEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKSKLG 369
C G + G G G + G + +F ++ G
Sbjct: 66 CF--GGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFG 103
Score = 32.7 bits (73), Expect = 0.57
Identities = 44/176 (25%), Positives = 56/176 (31%), Gaps = 58/176 (32%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G G G G S G + G GHG G S G G G GG++G
Sbjct: 465 GGGSFGGGYGGGSSGGGSSGG--GHGGGHGGSSGGGYGGGSSGGGSSGG----------- 511
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
G+G + G HG + G G
Sbjct: 512 -----------GYGGGSSSGG-------------------------HGGSSSGGYGGGSS 535
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G G GG+G GS GG G G GG + G+ +S+GS G + P
Sbjct: 536 GGGG-----GGYG-GGSSGGGSSSGGGYGGGSSS---GGHKSSSSGSVGESSSKGP 582
Score = 31.2 bits (69), Expect = 1.7
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 9/84 (10%)
Query: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS--AGSFGMNPQGAPWGQGGNGGP 201
+SGG+G G GG +G G + + G S GSFG G +G GG GG
Sbjct: 70 SSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFG----GGSFGGGGFGG- 124
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQ 225
FG G G G + + N+
Sbjct: 125 GGFGGGFGGGFG--GDGGLLSGNE 146
Score = 28.9 bits (63), Expect = 8.2
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 17/77 (22%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
G + RGS+ G G++ S G G FG GG G G GG G G
Sbjct: 81 GGGSFRGSY-GSSSFGGSYGGSFGGGSFG--GGSFGGGSFGGGGFG-----------GGG 126
Query: 184 FGMNPQGAPWGQGGNGG 200
FG G G GG+GG
Sbjct: 127 FG---GGFGGGFGGDGG 140
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 89.0 bits (219), Expect = 7e-18
Identities = 102/357 (28%), Positives = 135/357 (37%), Gaps = 59/357 (16%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKE---AGGAAGSKVSEALG 72
GSG + G+ +G+ G HG G S G G+ + + G GS S++ G
Sbjct: 798 GSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSG 857
Query: 73 QGTREAVGTGVRQVPGFGA-ADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
G G+ Q GFG + G G H G+ Q+ +HG + G
Sbjct: 858 YGQH---GSSSGQTSGFGQHRSSSGQYSGFGQHGSGSG------QSSGFGQHGTGS--GQ 906
Query: 132 WQGVPGHNGAWETS--GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
+ G H S G HG SQ G GQ HG FG +
Sbjct: 907 YSGFGQHESRSHQSSYGQHGSGSSQSS--GYGQ-----------HGSSSGQTFGFGQHRS 953
Query: 190 GAPWGQG------GNGGPPNFGTNTQGAVAQPGYGS--VRASNQNEGCTNPPPSGSGGGS 241
G+ G G+G FG + G+ G+G R+S N G GSG
Sbjct: 954 GSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYG-----QHGSGSSQ 1008
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-GSSGGSSGNSGG----- 295
S+ G GS SG + +++G SG GS S SSG G G SG S G
Sbjct: 1009 SSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYE 1068
Query: 296 --SRGDSGSESSWGSSTGSSSGNHGGSGGGNG----HKPGCEKP---GNEARGSGES 343
SR S + GSS S G HG + G H+PG + G GSG+S
Sbjct: 1069 SRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQS 1125
Score = 88.6 bits (218), Expect = 9e-18
Identities = 106/356 (29%), Positives = 142/356 (39%), Gaps = 54/356 (15%)
Query: 17 GSGEAGPLQS-GEESTGTNIGEALG---HGLGDALSEGVGKAIGKEAGGAAGSKVSEALG 72
G E+ QS G + G++ G+ G HG G S G G+ +GS S G
Sbjct: 454 GQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQC-------GSGSGQSSGFG 506
Query: 73 QGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSW 132
Q G+ Q GFG ++ + + G HE + +HG+ + + S
Sbjct: 507 QH-----GSVSGQSSGFGQHGSVSGQ------SSGFGQHESRSRQSSYGQHGSGSSQSSG 555
Query: 133 QGVPGHNGAWETSG--GHGIFGSQG---GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMN 187
G G+ ETSG HG+ Q G G G G G G HG + FG +
Sbjct: 556 YG---QYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQ---HGSGSGQSSGFGQH 609
Query: 188 PQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
G ++G ++ G+ GYG S Q G GSG S G
Sbjct: 610 ES--------RSGQSSYGQHSSGSSQSSGYGQ-HGSRQTSGFGQ---HGSGSSQSTGFGQ 657
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG-GSSGNSG-GSRGDS-GSES 304
GS SG S + +G SSG S SG SS G G GSS +SG G G S G S
Sbjct: 658 YGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTS 717
Query: 305 SWGSSTGSS--SGNHGGSGGGNGHKPGCEKPGNEARGSGE-SGIQNSETSPGMFNF 357
+G SS S + G G G+G G G GSG+ SG E+ G ++
Sbjct: 718 GFGQHELSSGQSSSFGQHGSGSGQSSGF---GQHGSGSGQSSGFGQHESRSGQSSY 770
Score = 88.6 bits (218), Expect = 9e-18
Identities = 113/421 (26%), Positives = 154/421 (36%), Gaps = 93/421 (22%)
Query: 16 LGSGEAGPLQSGEESTGTNIGEALG---HGLGDALSEGVGK--------AIGKEAGGAA- 63
LGSG++ +G G+ G++ G HG G S G G+ + G+ + G++
Sbjct: 572 LGSGQS----TGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ 627
Query: 64 -------GSKVSEALGQ-GTREAVGTGVRQV-PGFGAADALGNRVGEAAHALGNTGHEIG 114
GS+ + GQ G+ + TG Q G G + G V + + G HE
Sbjct: 628 SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESR 687
Query: 115 RQAEDVIRHGADAVRGSWQGVPGHN-GAWETSGGHGIFGSQG---GLGGQGQGNPGGLGT 170
+HG + + S G G + G G H + Q G G G G G G
Sbjct: 688 SGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQ 747
Query: 171 PWVHGYPGNSAGSFGMNP----------------QGAPWGQGGNGGPPNFGTNTQGAVAQ 214
HG + FG + Q + +GQ G+ FG + G+
Sbjct: 748 ---HGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQS 804
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGS------SNSGGGSGSQSGSSGSGSNGDNNNGSS 268
G+G + + SGSG S S S S Q GS S S+G +GSS
Sbjct: 805 TGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSS 864
Query: 269 SGGSSS-----------------GSSSGGSSG-GSSGGSSGNSGG-------SRGDSGSE 303
SG +S GS SG SSG G G SG G S S +
Sbjct: 865 SGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQ 924
Query: 304 SSWGSSTGSSSGNHGGSGG----------GNGHKPGCEKPGNEARGSGE-SGIQNSETSP 352
GSS S G HG S G G+G G G GSG+ SG E+
Sbjct: 925 HGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGF---GQHGSGSGQSSGFGQHESGS 981
Query: 353 G 353
G
Sbjct: 982 G 982
Score = 85.9 bits (211), Expect = 6e-17
Identities = 101/361 (27%), Positives = 149/361 (41%), Gaps = 50/361 (13%)
Query: 26 SGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQ 85
SG G++ G+ G G + LS G + G+ +GS S GQ G+G Q
Sbjct: 704 SGYGQHGSSSGQTSGFGQHE-LSSGQSSSFGQHG---SGSGQSSGFGQH-----GSGSGQ 754
Query: 86 VPGFGAADALGNRVGEAAHALGNT-----GHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140
GFG ++ + H+ G++ G RQ +HG+ + + + G G +G
Sbjct: 755 SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG-SG 813
Query: 141 AWETSGGHGIFGSQGGLGGQGQG-------------NPGGLGTPWVHGYP--GNSAGS-- 183
+ +++G FG G GQ G G G+ GY G+S+G
Sbjct: 814 SGQSAG----FGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869
Query: 184 -FGMNP----QGAPWGQGGNGGPPN--FGTNTQGAVAQPGYG-----SVRASNQNEGCTN 231
FG + Q + +GQ G+G + FG + G+ G+G S ++S G +
Sbjct: 870 GFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGS 929
Query: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSG-SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSS 290
SG G S+SG G SGSG S+G +GS SG SS SG SSG
Sbjct: 930 SQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQ 989
Query: 291 GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSET 350
S S+ + G S GSS S G HG S G + G G+ G + ++
Sbjct: 990 HESRSSQSNYGQHGS-GSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQS 1048
Query: 351 S 351
S
Sbjct: 1049 S 1049
Score = 80.9 bits (198), Expect = 2e-15
Identities = 101/373 (27%), Positives = 162/373 (43%), Gaps = 62/373 (16%)
Query: 17 GSGEAGPLQS--GEESTGTNIGEALG-HGLGDALSEGVGK----AIGKEAGGAAGSKVSE 69
G+ E G Q+ G+ TG++ G +G G + S G+ + G+ + ++ ++ S+
Sbjct: 356 GARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSK 415
Query: 70 A--LGQGTREAV-----GTGVRQVPGF-----GAADALGNRVGEAAHALGNTGH-EIGRQ 116
G G+ ++ GTG+ Q GF G+ G ++ +LG H +
Sbjct: 416 CDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGK 475
Query: 117 AEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQG-----NPGGLGTP 171
+HG+ + + S G G +G+ ++SG FG G + GQ G + G +
Sbjct: 476 TSGFGQHGSGSGQSSGFGQCG-SGSGQSSG----FGQHGSVSGQSSGFGQHGSVSGQSSG 530
Query: 172 WVHGYPGNSAGSFGMNPQGAP----WGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE 227
+ + S+G + G+ +GQ G+ FG + G+ G+G
Sbjct: 531 FGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQY------- 583
Query: 228 GCTNPPPSGSGGGSSNSGGGSGSQSG-SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
GSG G S+ G GS SG SSG G + + SS G SSGSS SSG
Sbjct: 584 --------GSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ--SSGYGQ 633
Query: 287 GGSSGNSGGSRGDSGSESS-----WGSSTGSSSG---NHGGSGGGNGHKPGCEKPGNEAR 338
GS SG + SGS S +GS +G SSG + GSG +G + G+ +
Sbjct: 634 HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSS- 692
Query: 339 GSGESGIQNSETS 351
G+ G +S++S
Sbjct: 693 -YGQHGFGSSQSS 704
Score = 79.3 bits (194), Expect = 5e-15
Identities = 99/368 (26%), Positives = 148/368 (40%), Gaps = 50/368 (13%)
Query: 27 GEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAG-GAAGSKVSEALGQGTREAVGT 81
G+ +G++ G HG + G G+ + G+ +G G GS ++ G G GT
Sbjct: 846 GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQH---GT 902
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNT--------GHEIGR------------QAEDVI 121
G Q GFG ++ ++ H G++ G G+ Q+
Sbjct: 903 GSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFG 962
Query: 122 RHGADAVRGSWQGVPGHNGAWETSG--GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN 179
+HG+ + + S G +G+ ++SG H SQ G G G+ G +G G+
Sbjct: 963 QHGSGSGQSSGFG-QHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSG----YGQHGS 1017
Query: 180 SAGS---FGMNP----QGAPWGQGGNGGPPN--FGTNTQGAVAQPGYG-----SVRASNQ 225
S+G FG + Q + +GQ G+G + FG + G+ G+G S ++S
Sbjct: 1018 SSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYG 1077
Query: 226 NEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGS 285
G + SG G SNSG SG GSG + S G SSG GS G
Sbjct: 1078 QHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGK 1137
Query: 286 SGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGI 345
S G + + S S + GSS S G H SG G G G++ S I
Sbjct: 1138 SSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQH-ESGSGPTTSFGQHVSGSDNFSSSGQHI 1196
Query: 346 QNSETSPG 353
+S S G
Sbjct: 1197 SDSGQSTG 1204
Score = 77.0 bits (188), Expect = 3e-14
Identities = 90/361 (24%), Positives = 130/361 (36%), Gaps = 33/361 (9%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
GSG++ SG GT G+ G G ++ S + G+ G++ S G +
Sbjct: 890 GSGQS----SGFGQHGTGSGQYSGFGQHESRSHQ--SSYGQHGSGSSQSSGYGQHGSSSG 943
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
+ G G + G G + G + + G HE G G R S
Sbjct: 944 QTFGFGQHR-SGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGF--GQHESRSSQSNYG 1000
Query: 137 GHNGAWETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
H S G+G GS G GQ + + G HG + + FG + G+
Sbjct: 1001 QHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQ 1060
Query: 194 GQG-----GNGGPPNFGTNTQGAVAQPGYGSVRA-SNQNEGC-TNPPPSGSGGGSSNSGG 246
G ++G + G+ GYG + S Q G + P SG G G
Sbjct: 1061 SSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGS 1120
Query: 247 GSGSQSG----SSGSGSN----------GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
GSG SG SG+G + G ++ G GSS S G GS +S
Sbjct: 1121 GSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFG 1180
Query: 293 SGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSP 352
S D+ S S S S G G G+G G + ++ SG + ET+
Sbjct: 1181 QHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTH 1240
Query: 353 G 353
G
Sbjct: 1241 G 1241
Score = 76.6 bits (187), Expect = 3e-14
Identities = 96/356 (26%), Positives = 131/356 (36%), Gaps = 38/356 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGK---AIGKEAG------------ 60
GS G+ +G+ G HG G S G G+ GK +G
Sbjct: 939 GSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSN 998
Query: 61 -GAAGSKVSEALGQGTREAVGTGVRQVPGFGA-ADALGNRVGEAAHALGNTGHEIGRQAE 118
G GS S++ G G G+ Q GFG + G G H G+ Q+
Sbjct: 999 YGQHGSGSSQSSGYGQH---GSSSGQTTGFGQHRSSSGQYSGFGQHGSGSD------QSS 1049
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
+HG + + S G + G HG SQ GQ N G H PG
Sbjct: 1050 GFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHR-PG 1108
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ S G G+ GQ G GT AQ Y S ++S G + SG G
Sbjct: 1109 SGQSS-GFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCG 1167
Query: 239 GGSSNSGGGSG---SQSGSSGSGSNGD--NNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
S SG + SGS S+G +++G S+G GS SG S+G G S
Sbjct: 1168 QHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVE 1227
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSE 349
GS E++ G + ++ H SG G + G R S +S +SE
Sbjct: 1228 SGSTVHGRQETTHGQTINTT--RHSQSGQGQSTQTGSRV--TRRRRSSQSENSDSE 1279
Score = 69.7 bits (169), Expect = 4e-12
Identities = 89/330 (26%), Positives = 119/330 (36%), Gaps = 39/330 (11%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHG-LGDALSE-GVGKAIGKEAGGAAGSKVSEALGQGTR 76
G +G QS + + T A GH D+ GV A G AGS+ E+ G
Sbjct: 2008 GHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGES-GSSVH 2066
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
E GT G HA G R + R G+ S V
Sbjct: 2067 ERHGT------------THGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEV- 2113
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQG 196
H+G T GH ++ G G G GT +HG G++ GQ
Sbjct: 2114 -HSGVSHTHSGHTYGQARSQHGESGSAIHGRQGT--IHGQTGDTTRH----------GQS 2160
Query: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSG 256
G+G G+ T G S S+ +E + P+ SG S +G G QSGSSG
Sbjct: 2161 GHGQSTQTGSRTTGRQRS----SHSESSDSEVHSEASPTHSGHTHSQAGSRHG-QSGSSG 2215
Query: 257 SGSNGDNNN--GSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS 314
G G + G ++ + G G + G G SG S SWGS T S
Sbjct: 2216 HGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRG-SGHSESSDSEVHSWGSHT--HS 2272
Query: 315 GNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
G+ G G +PG G G++G
Sbjct: 2273 GHIQGQAGSQQRQPGSTVHGRLETTHGQTG 2302
Score = 60.1 bits (144), Expect = 3e-09
Identities = 106/413 (25%), Positives = 147/413 (35%), Gaps = 92/413 (22%)
Query: 25 QSGEE---STGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81
+SGEE +G+N E GHG LS G+ + G E+ + LG + +
Sbjct: 218 ESGEEYESGSGSNSWERKGHG---GLSCGL-ETSGHESNSTQSRIREQKLGSSCSGSGDS 273
Query: 82 GVRQ-VPGFGAADALGNRVGEAA----HALGNTGHEI-----GRQAEDVIRHGADAVRGS 131
G R G+ + G ++ H G G++ G Q+ G V G
Sbjct: 274 GRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSG- 332
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPW-----------VHGYPGNS 180
G P G E++ + SQ G G + G P G W +G G+
Sbjct: 333 --GQPSGCGQPESNPCSQSY-SQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQ 389
Query: 181 AGSFGMNPQGAPWGQGGNGGPPN-----------------FGTNTQGAVAQPGY-----G 218
+ S G + G+ G+ N N F + G G+ G
Sbjct: 390 SCSNGQHEYGS-CGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCG 448
Query: 219 SVRASNQNEGCTNPP--------PSGSGGGSSNSGGGSGSQSG----SSGSGSNGDNNNG 266
S + Q+E ++ SG G G GSG SG SGSG +
Sbjct: 449 SGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQH 508
Query: 267 SSSGGSSSGSSSGGSSGGSSGG-------SSGNSGGSRGDSGSESS----WGSSTGSSSG 315
S G SSG GS G S G S +S G G S+SS +GS S G
Sbjct: 509 GSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFG 568
Query: 316 NHG-GS---------GGGNGHKPGCEKPGNEARGSGE-SGIQNSETSPGMFNF 357
HG GS G G+G G G GSG+ SG E+ G ++
Sbjct: 569 QHGLGSGQSTGFGQYGSGSGQSSGF---GQHGSGSGQSSGFGQHESRSGQSSY 618
Score = 52.4 bits (124), Expect = 7e-07
Identities = 77/335 (22%), Positives = 112/335 (33%), Gaps = 52/335 (15%)
Query: 24 LQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGV 83
+Q+G +TG G GV G AGS E+ G E GT
Sbjct: 1941 IQTGSRTTGRR-GSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPES-GSSVHERHGT-- 1996
Query: 84 RQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWE 143
G H G++GH Q + + GH+G
Sbjct: 1997 ----------THGQTADTTRH--GHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSH 2044
Query: 144 TSGGH--GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSA----GSFGMNPQ--GAPWGQ 195
T GH G GSQ G G G HG G++ G + Q G+
Sbjct: 2045 THSGHAHGQAGSQHGESGSSVHERHGT----THGQTGDTTRHAHSGHGQSTQRGSRTAGR 2100
Query: 196 GGNGGPPNFGTNTQGAVAQPG----YGSVRASNQNEGCTNPPPSGSGGGSSN-------S 244
G+G + + V+ YG R+ + G G+ G + S
Sbjct: 2101 RGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQS 2160
Query: 245 GGGSGSQSGSSGSGSNGDNNNGSS------------SGGS-SSGSSSGGSSGGSSGGSSG 291
G G +Q+GS +G +++ SS SG + S S G SG S G G
Sbjct: 2161 GHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQG 2220
Query: 292 NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326
+ G GD+ + +G + G+ G+GH
Sbjct: 2221 TTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGH 2255
Score = 50.4 bits (119), Expect = 3e-06
Identities = 98/433 (22%), Positives = 147/433 (33%), Gaps = 107/433 (24%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALG---HGLGDALSEGVGK---AIGKEAGGAAGSKVSEA 70
GSG++ SG G+ G++ G HG G S G + G+ + G G+ S++
Sbjct: 1108 GSGQS----SGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQS 1163
Query: 71 LGQGTREAVGTGV-----RQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGA 125
G G E+ G+G + V G + G + ++ + G + G + G
Sbjct: 1164 SGCGQHES-GSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGE 1222
Query: 126 DAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG---------------- 169
S V G ET+ G I ++ GQGQ G
Sbjct: 1223 SQQVESGSTVHGRQ---ETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSE 1279
Query: 170 ---------TPWVHGYPGN---SAGSFGMNPQGAPWGQGGNG---GPPNFGTNTQGAVAQ 214
+ +H G+ +GS QG GQ G+ G G +TQ
Sbjct: 1280 VHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRT 1339
Query: 215 PG-----YGSVRASNQNEGCTNPPPS------------------------------GSGG 239
G + S + G ++ P S G
Sbjct: 1340 SGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEAT 1399
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSS-----SGGS----------SSGSSSGGSSGG 284
G +SG G +Q GS +G G ++ SS SGGS S G SG
Sbjct: 1400 GHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGS 1459
Query: 285 SSGGSSGNSGGSRGDSGSESSW--GSST--GSSSGNHGGSGGGNGHKPGCEKPGNEARGS 340
+ G G + G GD+ + + G ST GSS+ GSG G+
Sbjct: 1460 TVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSG 1519
Query: 341 ---GESGIQNSET 350
G+SG Q+ E+
Sbjct: 1520 HTHGQSGSQHGES 1532
Score = 47.8 bits (112), Expect = 2e-05
Identities = 92/382 (24%), Positives = 131/382 (34%), Gaps = 61/382 (15%)
Query: 17 GSGEAGPLQSGEESTGTN---IGEALGH---GLGDALSEGVGKAIGKEAGGAAGSKVSEA 70
GS P + E GT IG+ GH G G + G + G++ + S SE
Sbjct: 1603 GSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRG-SRTTGRQRSSHSESSDSE- 1660
Query: 71 LGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG------ 124
V +GV G++ G++ + Q D RH
Sbjct: 1661 --------VHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGL 1712
Query: 125 --ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAG 182
R + + GH+ ++ G G+ + G + G VH G G
Sbjct: 1713 TTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHG 1772
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS------- 235
G + A G+G G+ T G + G+ S + G + P S
Sbjct: 1773 QTGDTTRHA---HSGHGQSTQTGSRTTGRRSS-GHSEYSDSEGHSGFSQRPHSRGHTHGQ 1828
Query: 236 -GSGGGSSNS-------------GGGSG-SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280
GS G S S G SG SQSG S +G + G G S S S
Sbjct: 1829 AGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEV 1888
Query: 281 SSGGS---SGGSSGNSGGSRGDSGS-----ESSWGSSTGSSSGNHGGSGGGNGHKPGCEK 332
SGGS SG + + G+S S + TG ++ HG G + G
Sbjct: 1889 HSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTT-EHGHPSHGQTIQTGSRT 1947
Query: 333 PGNEARGSGESGIQNSETSPGM 354
G RGSG S +SE G+
Sbjct: 1948 TGR--RGSGHSEYSDSEGPSGV 1967
Score = 47.0 bits (110), Expect = 3e-05
Identities = 85/348 (24%), Positives = 115/348 (33%), Gaps = 37/348 (10%)
Query: 19 GEAGPLQSGEESTGTNIGEALGHG-LGDAL-----SEGVGKAIGKEAGGAAGSKVSEALG 72
G+AG Q GE + + HG GD G G G GS SE+
Sbjct: 2052 GQAGS-QHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSD 2110
Query: 73 QGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSW 132
V + +G A + G A H T H Q D RHG S
Sbjct: 2111 SEVHSGV-SHTHSGHTYGQARSQHGESGSAIHGRQGTIHG---QTGDTTRHGQ-----SG 2161
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN---SAGSFGMNPQ 189
G G+ T + +P G H G+ +GS G Q
Sbjct: 2162 HGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGH--THSQAGSRHGQSGSSGHGRQ 2219
Query: 190 GAPWGQGGNG---GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS-GSGGGSSNSG 245
G GQ G+ +G +TQ G R S +E + S GS S +
Sbjct: 2220 GTTHGQTGDTTRHAHYGYGQSTQRGSRTTGR---RGSGHSESSDSEVHSWGSHTHSGHIQ 2276
Query: 246 GGSGSQSGSSGSGSNG--DNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
G +GSQ GS +G + +G + + G S G S +G S + + S
Sbjct: 2277 GQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQST-QTGSRSSRASHFQSHSSER 2335
Query: 304 SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351
GSS G++G + GH G G I NS S
Sbjct: 2336 QRHGSSQVWKHGSYGPAEYDYGH------TGYGPSGGSRKSISNSHLS 2377
Score = 42.4 bits (98), Expect = 7e-04
Identities = 76/330 (23%), Positives = 109/330 (33%), Gaps = 50/330 (15%)
Query: 40 GHGLGDALSE-GVGKAIGKEAGGAAGSKVSEALG-------QGTREAVGTGVRQVPGFGA 91
GH G A S+ G ++I E G + + G Q T+ T R+ G
Sbjct: 1823 GHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSE 1882
Query: 92 ADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGAD--AVRGSWQGVPGHNGAWETSGGHG 149
+ H+ G+ H ++ +HG V Q G G T GH
Sbjct: 1883 SS------DSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGD-TTEHGHP 1935
Query: 150 IFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNP--QGAPWGQGGNGGPPNFGTN 207
G G + G G H +S G G++ G GQ G+ P +
Sbjct: 1936 SHGQTIQTGSRTTGRRGS-----GHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPES---- 1986
Query: 208 TQGAVAQPGYGSVR---ASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNN 264
G+ +G+ A G + S G + SG S G +G ++
Sbjct: 1987 --GSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSH 2044
Query: 265 NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324
S +GS G SG S G + G GD + H SG G
Sbjct: 2045 THSGHAHGQAGSQHG-ESGSSVHERHGTTHGQTGD--------------TTRHAHSGHGQ 2089
Query: 325 GHKPGCEKPGNEARGSGESGIQNSETSPGM 354
+ G G RGSG S +SE G+
Sbjct: 2090 STQRGSRTAGR--RGSGHSESSDSEVHSGV 2117
Score = 41.2 bits (95), Expect = 0.002
Identities = 83/338 (24%), Positives = 113/338 (33%), Gaps = 71/338 (21%)
Query: 72 GQGTREAVGTGVRQVPGFGAADALGNRVGEAA----HALGNTGHEIGRQ---AEDVIRHG 124
GQ T+ T RQ F +DA + V H+ T + G Q +E +
Sbjct: 1330 GQSTQTGSRTSGRQ--RFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHER 1387
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGG--LGGQGQGNP---------GGLGTPW- 172
+ G GH + GHG +G G +G G+ GG P
Sbjct: 1388 HETTYGQTGEATGHGHS-----GHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQS 1442
Query: 173 ---VHGYPGNSAGSFGMNPQGAPWGQGGNGGPP------NFGTNTQGAVAQPGYGSVRAS 223
HG G+ G G G G G + G +TQ + G R S
Sbjct: 1443 QEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGR---RGS 1499
Query: 224 NQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS--------------GSNGDNNNGSSS 269
+E + SG GS G + QSGS G GD S S
Sbjct: 1500 GHSESSDSEVHSG---GSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYS 1556
Query: 270 G---GSSSGSSSGG---SSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS-------GN 316
G + +GS + G +S S S +SGGS E ++G +
Sbjct: 1557 GHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHER 1616
Query: 317 HGGSGGGNGHKPGCEKPG---NEARGSGESGIQNSETS 351
HG + G G G G + RGS +G Q S S
Sbjct: 1617 HGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHS 1654
Score = 33.5 bits (75), Expect = 0.33
Identities = 57/241 (23%), Positives = 82/241 (34%), Gaps = 36/241 (14%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFG-MNPQGA 191
+ PGH + S S+G G G+ G HG G G ++ G
Sbjct: 120 EDTPGHKSGYRHSSW-----SEGEEHGYSSGHSRGT-VKCRHGSNSRRLGRQGNLSSSGN 173
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ 251
G + G + G + G SV + ++ PS G SG GS S
Sbjct: 174 QEGSQKRYHRSSCGHSWSGGKDRHGSSSVEL-RERINKSHISPSRESGEEYESGSGSNSW 232
Query: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES---SWGS 308
+ G S G +SG S + G+S GDSG S + +
Sbjct: 233 ERKG--------HGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSN 284
Query: 309 STG--------SSSGNHGGSGGGNGH---KPGCEKPGNEARGSG------ESGIQNSETS 351
S+G SS +H G GN + GC+ +G G SG E++
Sbjct: 285 SSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESN 344
Query: 352 P 352
P
Sbjct: 345 P 345
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 87.8 bits (216), Expect = 1e-17
Identities = 50/114 (43%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS--SGNSG 294
SGGGS GGG GSS G +G GG SGGSS GS GGS SG G
Sbjct: 513 SGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGG 572
Query: 295 GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNS 348
G G GS SS G G S G GGS GG G G RGS G+++S
Sbjct: 573 GGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSS 626
Score = 80.9 bits (198), Expect = 2e-15
Identities = 49/112 (43%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Query: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
GYGS +S + G + SG GGG GSG S SG GS G G G SG
Sbjct: 524 GYGSGGSSYGSGGGSYG--SGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSG 581
Query: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
SSSGG GGS GG G+SGG GS GSSSG SGG + K
Sbjct: 582 SSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVK 633
Score = 79.7 bits (195), Expect = 4e-15
Identities = 55/136 (40%), Positives = 66/136 (48%), Gaps = 20/136 (14%)
Query: 175 GYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPP 234
G G G +G G+ +G GG ++G+ G + YGS +S
Sbjct: 516 GSRGGGGGGYGSG--GSSYGSGGG----SYGSGGGGGGGRGSYGSGGSSY---------- 559
Query: 235 SGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG 294
GSGGGS SGGG G GS GSGS+ G S GG S GS GGSSGGS G G
Sbjct: 560 -GSGGGSYGSGGGGGGH-GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRG 617
Query: 295 GSRGDSGSESSWGSST 310
S G G +SS GSS+
Sbjct: 618 SSSG--GVKSSGGSSS 631
Score = 76.3 bits (186), Expect = 4e-14
Identities = 47/117 (40%), Positives = 55/117 (47%), Gaps = 7/117 (5%)
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
G S G S S S+ + G S GG G SGGSS GS GGS G+ GG G
Sbjct: 488 GEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGG 547
Query: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGH-------KPGCEKPGNEARGSGESGIQNS 348
GS S GSS GS G++G GGG GH G + G+ G G SG + S
Sbjct: 548 GRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGS 604
Score = 69.3 bits (168), Expect = 5e-12
Identities = 58/147 (39%), Positives = 67/147 (45%), Gaps = 33/147 (22%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G G G SGG +GS GG G G G GG G+ +G G+S GS G +
Sbjct: 516 GSRGGGGGGYGSGGSS-YGSGGGSYGSGGGGGGGRGS---YGSGGSSYGS-----GGGSY 566
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G GG GG G+GS + + + G GSGGG S GG GS G
Sbjct: 567 GSGGGGG---------------GHGSYGSGSSSGGYRG----GSGGGGGGSSGGRGSGGG 607
Query: 254 SSGSGSNGDNNNGSSSGG--SSSGSSS 278
SSG G GSSSGG SS GSSS
Sbjct: 608 SSGGSIGG---RGSSSGGVKSSGGSSS 631
Score = 62.4 bits (150), Expect = 7e-10
Identities = 42/122 (34%), Positives = 53/122 (43%), Gaps = 5/122 (4%)
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGG 295
G GGGS +GGG GS+S + GS + + + GG SG G GG GG G G
Sbjct: 50 GGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGF 109
Query: 296 SRGDSGSESSWGSSTGS---SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ--NSET 350
G G G +G G GG G G G+ P C G + +S +Q N E
Sbjct: 110 GGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEI 169
Query: 351 SP 352
P
Sbjct: 170 DP 171
Score = 62.0 bits (149), Expect = 9e-10
Identities = 49/170 (28%), Positives = 57/170 (33%), Gaps = 7/170 (4%)
Query: 205 GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNN 264
G + G + G + + + G GG S+ GGG GS G GS N
Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVN 69
Query: 265 NGSSSG-------GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
G S G GS GG GG G G GG G G GS G
Sbjct: 70 LGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGF 129
Query: 318 GGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKSK 367
GG G G G G P G E I S P D + KS+
Sbjct: 130 GGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/116 (35%), Positives = 46/116 (39%), Gaps = 12/116 (10%)
Query: 241 SSNSG--GGSGSQSGSSGSGSNGDNNNGSS---SGGSSSGSSSGGSSGGSSGGSSG---- 291
SS SG G G SGS+G + SS SGG SS G GGS G G
Sbjct: 6 SSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSR 65
Query: 292 ---NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
N GGS+ S S + G G +GG G G G G G G G G
Sbjct: 66 SLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGG 121
Score = 46.2 bits (108), Expect = 5e-05
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 265 NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN 324
N S S +S + SGG S G GG G+ G S G G S+GS G G GG+
Sbjct: 500 NVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGG--SYGSGGGGGGGRGSYGSGGS 557
Query: 325 GHKPGCEKPGNEARGSGESGIQNSETSPG 353
+ G G+ G G + +S G
Sbjct: 558 SYGSGGGSYGSGGGGGGHGSYGSGSSSGG 586
Score = 42.7 bits (99), Expect = 5e-04
Identities = 37/113 (32%), Positives = 44/113 (38%), Gaps = 21/113 (18%)
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS-FGMNPQGAPWGQGGNGGPPNF 204
GG G FG+ GG G + N GG + + G GS FG G +G GG GG
Sbjct: 51 GGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGG---- 106
Query: 205 GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG-GSGSQSGSSG 256
G G + G+G GSGGG GG G G G G
Sbjct: 107 GGFGGGGIGGGGFGGF---------------GSGGGGFGGGGFGGGGYGGGYG 144
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/95 (31%), Positives = 33/95 (34%), Gaps = 1/95 (1%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-SGSQS 252
G GG G ++ V G S+ S G G GG GGG G
Sbjct: 50 GGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGF 109
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG 287
G G G G GS GG G GG GG G
Sbjct: 110 GGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG 144
Score = 39.3 bits (90), Expect = 0.006
Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 7/137 (5%)
Query: 65 SKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
S++S +V T + G G+ G G + G+ G G G
Sbjct: 491 SRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRG 550
Query: 125 ADAVRGSWQGVPGHN-GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
+ GS G G + G+ GGHG +GS GG +G GG G G GS
Sbjct: 551 SYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY-RGGSGGGG-----GGSSGGRGS 604
Query: 184 FGMNPQGAPWGQGGNGG 200
G + G+ G+G + G
Sbjct: 605 GGGSSGGSIGGRGSSSG 621
Score = 35.4 bits (80), Expect = 0.088
Identities = 40/150 (26%), Positives = 55/150 (36%), Gaps = 22/150 (14%)
Query: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
SGE P S ST G G G G G G GS S G G R
Sbjct: 494 SGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSG---GSSYGSGGGSYGSGGGGGGGRG 550
Query: 78 AVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPG 137
+ G+G G+ G + G+ G G + +G+ + G ++G G
Sbjct: 551 SYGSG-------------GSSYGSGGGSYGSGGGGGGHGS-----YGSGSSSGGYRGGSG 592
Query: 138 HNGAWETSG-GHGIFGSQGGLGGQGQGNPG 166
G + G G G S G +GG+G + G
Sbjct: 593 GGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622
Score = 30.8 bits (68), Expect = 2.2
Identities = 36/134 (26%), Positives = 46/134 (34%), Gaps = 7/134 (5%)
Query: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNR- 98
G+ G S G I + + S G G + G G FGA G+R
Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGS---FGAGGGFGSRS 66
Query: 99 ---VGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQG 155
+G + + GR + +G G G G G GG G FGS G
Sbjct: 67 LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGG 126
Query: 156 GLGGQGQGNPGGLG 169
G G G GG G
Sbjct: 127 GGFGGGGFGGGGYG 140
Score = 30.8 bits (68), Expect = 2.2
Identities = 40/147 (27%), Positives = 52/147 (35%), Gaps = 22/147 (14%)
Query: 56 GKEAGGAAG--SKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEI 113
G + G+AG + TR + G G R G + G G + +L N G
Sbjct: 15 GGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSK 74
Query: 114 GRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV 173
G + G G G G GG G GG+GG G G
Sbjct: 75 SISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFG----GGGIGGGGFG---------- 120
Query: 174 HGYPGNSAGSFGMNPQGAPWGQGGNGG 200
G+ G+ G FG G +G GG GG
Sbjct: 121 -GF-GSGGGGFG----GGGFGGGGYGG 141
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 87.4 bits (215), Expect = 2e-17
Identities = 88/311 (28%), Positives = 107/311 (34%), Gaps = 46/311 (14%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G++ +PG G + GE G+ G A DA +G PG GA
Sbjct: 639 GLQGLPGTGGPPGENGKPGEPGPK-GDAG------APGAPGGKGDAGAPGERGPPGLAGA 691
Query: 142 WETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQG---APWGQGG 197
GG G G +GG G G G PG GTP + G PG G P+G P G G
Sbjct: 692 PGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751
Query: 198 NGGPPNFGTNTQ-------------------GAVAQPGYGSVRASNQNEGCTNPP-PSGS 237
+G P G GA PG R S G T PP P+G
Sbjct: 752 DGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811
Query: 238 GGGSSNSG--GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG--------GSSGGSSG 287
G +G GG G + G G GGS G GS GG
Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGA 871
Query: 288 GSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH-----KPGCEKPGNEARGSGE 342
+ G G GS + G S S G G G+ PG P +A GE
Sbjct: 872 AGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGE 931
Query: 343 SGIQNSETSPG 353
G ++ PG
Sbjct: 932 KGSPGAQGPPG 942
Score = 77.8 bits (190), Expect = 2e-14
Identities = 95/346 (27%), Positives = 116/346 (33%), Gaps = 27/346 (7%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G+ A L+ G G N + G+ G+ G + E G
Sbjct: 420 GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP 479
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHA--LGNTGHEIGRQAEDVIRHGADAVRGS--W 132
A G R PGF GE A G G R A G D V G
Sbjct: 480 GAAGE--RGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG--EPGRDGVPGGPGM 535
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGA 191
+G+PG G + G G GSQG G G P G G P V G+PG G
Sbjct: 536 RGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE 595
Query: 192 PWGQGGNG--GPP--NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
G GG G GPP N T QG G G ++G T PP G +GG
Sbjct: 596 RGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG------DKGDTGPPGPQGLQGLPGTGGP 649
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307
G G GD + GG + G G+ G GG+ G G E G
Sbjct: 650 PGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGA-GPPGPEG--G 706
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
G G +G PG + E G G G + + PG
Sbjct: 707 KGAAGPPGPPGAAG-----TPGLQGMPGERGGLGSPGPKGDKGEPG 747
Score = 74.3 bits (181), Expect = 2e-13
Identities = 86/316 (27%), Positives = 109/316 (34%), Gaps = 32/316 (10%)
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
G G + G +A G R PG A L G G E G+ A
Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP-------GPEGGKGAAGP 712
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWV 173
A QG+PG G + G G G GG G G +G G +G P
Sbjct: 713 PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772
Query: 174 HGYPGNSA--GSFGM----NPQGAPWGQGGNGGPPNFG--TNTQGAVAQPGYGSVRASNQ 225
G PG+ G+ G+ P+G+P G+ G GPP G +PG R +
Sbjct: 773 AGQPGDKGEGGAPGLPGIAGPRGSP-GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPG 831
Query: 226 NEGCTNPP-----PSGSG-GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG 279
+G PP P GSG G G G + G G+ G G S + G
Sbjct: 832 EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPG 891
Query: 280 GSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEA 337
S G G G G+ G GS G + GS G G PG P A
Sbjct: 892 PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG-PPGAPGPLGIA 950
Query: 338 RGSGESGIQNSETSPG 353
+G G+ PG
Sbjct: 951 GITGARGLAGPPGMPG 966
Score = 72.0 bits (175), Expect = 8e-13
Identities = 73/294 (24%), Positives = 100/294 (34%), Gaps = 34/294 (11%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVI--RHGADAVRGSWQGVPGHN 139
G+ PG R GE G TG G + E+ + +GA G +G PG
Sbjct: 255 GIPGFPGMKGHRGFDGRNGEK----GETGAP-GLKGENGLPGENGAPGPMGP-RGAPGER 308
Query: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG 199
G G G G+ G G GQ PG G P G+PG+ + P G+P G G
Sbjct: 309 GRPGLPGAAGARGNDGARGSDGQ--PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366
Query: 200 -----------------GPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
GPP + G + G + + G PP G+
Sbjct: 367 QRGEPGPQGHAGAQGPPGPPGIN-GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDS 300
GG+G + G G +G + G S G G +G G+ G+
Sbjct: 426 GLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGER 485
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGM 354
G+ G + + G G G PG P +GE G PGM
Sbjct: 486 GAPGFRGPAGPNGIPGEKGPAGERG-APG---PAGPRGAAGEPGRDGVPGGPGM 535
Score = 67.8 bits (164), Expect = 2e-11
Identities = 70/229 (30%), Positives = 90/229 (39%), Gaps = 15/229 (6%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGM-NPQGA 191
G PG G G G G +G G QG G PG LG + G G AG GM P+G+
Sbjct: 912 GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG-LAGPPGMPGPRGS 970
Query: 192 PWGQG--GNGGPP--NFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
P QG G G P N + +G G + + G P S G S GG
Sbjct: 971 PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030
Query: 248 SGSQSGSSGSGSNGDNNNGSSSG--GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
G + + G+ G + G G + S G SG + + GSRG G +
Sbjct: 1031 KGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGS-GESGIQNSETSPG 353
G G+ G GH+ PG A GS G +G Q + SPG
Sbjct: 1091 RGD---KGETGERGAAGIKGHRGFPGNPG--APGSPGPAGQQGAIGSPG 1134
Score = 62.0 bits (149), Expect = 9e-10
Identities = 66/240 (27%), Positives = 84/240 (35%), Gaps = 21/240 (8%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQG 190
+QG PG G SG G G+ G G G+ G G G P G PG G G P G
Sbjct: 199 YQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG-PPGIKG--PAG 255
Query: 191 APWGQGGNGGPPNFGTNTQ-GAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSSNSG--G 246
P G G G N + G PG G P P G+ G G G
Sbjct: 256 IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPG 315
Query: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSES 304
+G++ GS+G G + S G GS G++G G RG+ G +
Sbjct: 316 AAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQG 375
Query: 305 SWGSSTGSSSGNHGGSGGGNGHK-----------PGCEKPGNEARGSGESGIQNSETSPG 353
G+ GS GG G G P A +G G++ PG
Sbjct: 376 HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435
Score = 62.0 bits (149), Expect = 9e-10
Identities = 105/390 (26%), Positives = 134/390 (34%), Gaps = 71/390 (18%)
Query: 17 GSGEAGPLQSGEEST-GTNIGEALGHGLGDALSEGVGKAIGKEAG--GAAGSKVSEALGQ 73
G G+AG GE G L G G EG GK G GAAG+ + +
Sbjct: 673 GKGDAGA--PGERGPPGLAGAPGLRGGAGPPGPEG-GKGAAGPPGPPGAAGTPGLQGM-P 728
Query: 74 GTREAVGT----GVRQVPGFGAADALGNRVGEAAHA--LGNTGHEIGRQAEDVIRHGADA 127
G R +G+ G + PG AD + + G +G G Q D GA
Sbjct: 729 GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP--AGQPGDKGEGGAPG 786
Query: 128 VRG--SWQGVPGHNGAWETSGGHGIFGS---QGGLGGQGQ----GNPGGLGTPWVHGYPG 178
+ G +G PG G G G G+ G GG+G+ G G G P V G PG
Sbjct: 787 LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG 846
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGS 237
S + PQG +G GGP GA PG + + G PP PSGS
Sbjct: 847 GSGPAGPPGPQGVKGERGSPGGP--------GAAGFPGARGLPGPPGSNGNPGPPGPSGS 898
Query: 238 GG-----------------------GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274
G G + G GS G+ G +G
Sbjct: 899 PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958
Query: 275 GSSSG-----GSSG-----GSSGGSSGNS-GGSRGDSGSESSWGSSTGSSSGNHGGSGGG 323
G GS G G SG N G RG G + G + + G+ G
Sbjct: 959 AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018
Query: 324 NGHKPGCEKPGNEARGSGESGIQNSETSPG 353
+G PG G G+ G S +PG
Sbjct: 1019 DGLPGRDGSPG----GKGDRGENGSPGAPG 1044
Score = 61.6 bits (148), Expect = 1e-09
Identities = 69/225 (30%), Positives = 80/225 (35%), Gaps = 25/225 (11%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGN 179
G V+G G PG NG G G G G G G+ GNPG G P G PG
Sbjct: 972 GPQGVKGE-SGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030
Query: 180 SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSG 238
GAP G G+ GPP G V G R + G P P+GS
Sbjct: 1031 KGDRGENGSPGAP-GAPGHPGPP-------GPVGPAGKSGDRGESGPAGPAGAPGPAGSR 1082
Query: 239 GGSSNSG-----GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSG--GSS 290
G G G +G + + G G N + G G S G +G G
Sbjct: 1083 GAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPV 1142
Query: 291 GNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP 333
G SG G G SG G + GS G GH PG P
Sbjct: 1143 GPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGH-PGQPGP 1186
Score = 60.8 bits (146), Expect = 2e-09
Identities = 64/238 (26%), Positives = 81/238 (34%), Gaps = 22/238 (9%)
Query: 134 GVPGHNGAWETSGGHGIFGS---QGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQ 189
G PG G TSG G GS QG G GQ P G G P G P AG G + +
Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG-PSGPAGKDGESGR 235
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVR------ASNQNEGCTNPPPSGSGGGSSN 243
G+ G GPP +G PG+ ++ N +G T P G
Sbjct: 236 PGRPGERGLPGPPGI----KGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPG 291
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSG 301
G G G G ++G + + G G G +G GS G G
Sbjct: 292 ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKG 351
Query: 302 SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG-----NEARGSGESGIQNSETSPGM 354
GS + + G G GH PG G GE G +PG+
Sbjct: 352 EVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGL 409
Score = 52.4 bits (124), Expect = 7e-07
Identities = 63/230 (27%), Positives = 80/230 (34%), Gaps = 31/230 (13%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGS 183
GA+ + G +G PG G +G G G G G G PG G+P G G +
Sbjct: 984 GANGLSGE-RGPPGPQGLPGLAGTAGEPGRDGNPGSDGL--PGRDGSPGGKGDRGENGS- 1039
Query: 184 FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSN 243
GAP G G+ GPP G V G R + P+G G
Sbjct: 1040 -----PGAP-GAPGHPGPP-------GPVGPAGKSGDRGES--------GPAGPAG---- 1074
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
+ G +GS+ G GD G + G + GS G G +G GS
Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG-PAGQQGAIGSP 1133
Query: 304 SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
G G G +GH PG P GE G + S PG
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGH-PGPIGPPGPRGNRGERGSEGSPGHPG 1182
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/201 (26%), Positives = 67/201 (33%), Gaps = 12/201 (5%)
Query: 161 GQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220
GQG G G P G PG + G+P G G + T Q Q V
Sbjct: 101 GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDV 160
Query: 221 RASNQNEGCTN-PPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSS 277
++ G P P+G G G + G GS G G+ SG +
Sbjct: 161 KSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGA 220
Query: 278 SGGSSGGSSGGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEK 332
G S G SG G G G G + G H G G NG K
Sbjct: 221 IGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGA 280
Query: 333 PGNEARGSGESGIQNSETSPG 353
PG + GE+G+ +PG
Sbjct: 281 PGLK----GENGLPGENGAPG 297
Score = 49.3 bits (116), Expect = 6e-06
Identities = 48/175 (27%), Positives = 60/175 (34%), Gaps = 22/175 (12%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAG 182
G RG G G GA +G G G QG G +G+ G G G G+PGN
Sbjct: 1059 GKSGDRGE-SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP-- 1115
Query: 183 SFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
GAP G+ GP QGA+ PG R G + PP G
Sbjct: 1116 -------GAP----GSPGP----AGQQGAIGSPGPAGPRGP---VGPSGPPGKDGTSGHP 1157
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297
G G + GS G + G + G GG + GG +
Sbjct: 1158 GPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212
Score = 44.7 bits (104), Expect = 1e-04
Identities = 58/240 (24%), Positives = 75/240 (31%), Gaps = 32/240 (13%)
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQ------ 189
G G G GI G G G GQ G+PG G P + G +PQ
Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGI--CESCPTGPQNYSPQYDSYDV 160
Query: 190 ------GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSN 243
G G G GPP G PG S + G PP G S
Sbjct: 161 KSGVAVGGLAGYPGPAGPP-------GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSG 213
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--------G 295
G G+ S +G +G++ G G G G G G
Sbjct: 214 PPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNG 273
Query: 296 SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG--NEARGSGESGIQNSETSPG 353
+G++G+ G + G G G +PG A G G + S+ PG
Sbjct: 274 EKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPG 333
Score = 38.1 bits (87), Expect = 0.014
Identities = 38/141 (26%), Positives = 49/141 (34%), Gaps = 23/141 (16%)
Query: 124 GADAVRGSWQGVPGHNGAWETSGGHGI---FGSQGGLGGQGQGNPGGLGTPWVHGYPGNS 180
G RG+ G+ GH G G G G QG +G G P G P G PG
Sbjct: 1095 GETGERGA-AGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGP--SGPPGKD 1151
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG 240
S P G P +G G +G+ PG+ G PP G
Sbjct: 1152 GTSGHPGPIGPPGPRGNRG--------ERGSEGSPGH---------PGQPGPPGPPGAPG 1194
Query: 241 SSNSGGGSGSQSGSSGSGSNG 261
G G+ + +G G + G
Sbjct: 1195 PCCGGVGAAAIAGIGGEKAGG 1215
Score = 36.2 bits (82), Expect = 0.051
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 10/79 (12%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-------GNPGGLGTPWVHGYPGNSAGSFGM 186
G PG +G TSG G G G G +G+ G+PG G P G PG G G
Sbjct: 1146 GPPGKDG---TSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGA 1202
Query: 187 NPQGAPWGQGGNGGPPNFG 205
G+ G P +G
Sbjct: 1203 AAIAGIGGEKAGGFAPYYG 1221
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/216 (31%), Positives = 80/216 (37%), Gaps = 26/216 (12%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
ED G D + G G+ G GG G G +GG GG G G GY
Sbjct: 382 EDSRPSGGDFRGRGYGGERGYRGR----GGRG--GDRGGYGGDRSGGGYGGDRSSGGGYS 435
Query: 178 GN-SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG 236
G+ S G +G + G +G GG +G + G GYG R
Sbjct: 436 GDRSGGGYGGDRSGGGYGGDRGGG---YGGDRGG-----GYGGDRGGGYG--------GD 479
Query: 237 SGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
GG + GGG G G G G GD G G S G GG GG SG
Sbjct: 480 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 539
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
G G G + S G G G +GG GG G K G
Sbjct: 540 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 575
Score = 72.4 bits (176), Expect = 6e-13
Identities = 54/168 (32%), Positives = 65/168 (38%), Gaps = 16/168 (9%)
Query: 194 GQGGNGGPPN-FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
G+GG GG +G + G GYG R+S G + SG G G SGGG G
Sbjct: 404 GRGGRGGDRGGYGGDRSGG----GYGGDRSSG---GGYSGDRSGGGYGGDRSGGGYGGDR 456
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSS-GGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
G G G G GG GG GG GG G GG RG +G G
Sbjct: 457 GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG------GYGGDRG 510
Query: 312 SSSGNHGGSGGGNGHKP-GCEKPGNEARGSGESGIQNSETSPGMFNFD 358
G+ GG GG G ++ G G SG + S G + D
Sbjct: 511 GYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD 558
Score = 72.0 bits (175), Expect = 8e-13
Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 15/188 (7%)
Query: 122 RHGADAVRGSWQGVP---GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
R G RG + G G+ G + GG+ S GG GG G GG G GY G
Sbjct: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGG 462
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ G +G + G G GG+ G +G + G GYG R + G
Sbjct: 463 DRGGGYGGDRGG---GYGGDRG--GYGGDRGG-----GYGGDRGGYGGDRGGYGGDRGGY 512
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
GG GG S+ G G G G SGG S GG G GG G+ GG G
Sbjct: 513 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 572
Query: 299 DSGSESSW 306
G + +
Sbjct: 573 KMGGRNDY 580
Score = 65.5 bits (158), Expect = 8e-11
Identities = 55/194 (28%), Positives = 69/194 (35%), Gaps = 32/194 (16%)
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE--GCTNPPPS 235
G+ G G G G GG P G P G++ + +N C P P
Sbjct: 326 GSGGGRRGRGGYRGRGGFQGRGGDPKSG---DWVCPNPSCGNMNFARRNSCNQCNEPRPE 382
Query: 236 ---------------------GSGGGSSNSGGGSGSQSGSS--GSGSNGDNNNGSSSGGS 272
G GG + GG G +SG G S+G +G SGG
Sbjct: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442
Query: 273 SSGSSSGGSSGGSSGGSSG--NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
G SGG GG GG G GG GD G +G G G+ GG GG+ G
Sbjct: 443 YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG--GGYGGDRGGYGGDRGGGYGGDRGGYGG 500
Query: 331 EKPGNEARGSGESG 344
++ G G G
Sbjct: 501 DRGGYGGDRGGYGG 514
Score = 50.8 bits (120), Expect = 2e-06
Identities = 59/215 (27%), Positives = 79/215 (36%), Gaps = 45/215 (20%)
Query: 152 GSQGGLGGQGQ-----GNPGGLG----TPWVHGYPGNSAGSFGMNPQG-APWGQGGNGGP 201
GS G GG+ Q GNPG G + GY + S+G N G + +GQ +
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG--------------SSNSGGG 247
+ Q + +Q Y +NQ + N SGS GG S + G
Sbjct: 65 GGYENQKQSSYSQQPY-----NNQGQQ-QNMESSGSQGGRAPSYDQPDYGQQDSYDQQSG 118
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS--------------GGSSGGSSGNS 293
GS SN D + S S S S + G + G G+
Sbjct: 119 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQ 178
Query: 294 GGSRGDSGSESSW-GSSTGSSSGNHGGSGGGNGHK 327
GG RG G + G TGSS G+ GG GH+
Sbjct: 179 GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR 213
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 14/178 (7%)
Query: 36 GEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG---AA 92
G+ G G G S G G + + GG G + G G G G + G+G
Sbjct: 417 GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR--SGGGYGGDRGGGYGGDRGGGYGGDRGG 474
Query: 93 DALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFG 152
G+R G G G + G D +G D RG + G G G + GG+G G
Sbjct: 475 GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD--RGGYGGDRGGYGGDRSRGGYG--G 530
Query: 153 SQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ 209
+GG G G GG G GY G+ G +G G G GG G N N Q
Sbjct: 531 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG----GDRGGYGGKMGGRNDYRNDQ 584
Score = 45.8 bits (107), Expect = 6e-05
Identities = 47/154 (30%), Positives = 51/154 (33%), Gaps = 42/154 (27%)
Query: 230 TNPPPSGSGGGSSNSGGGSGSQSGSSG-SGSNGDNNNGS--------------------- 267
T P GGGS G G G G G GD +G
Sbjct: 316 TRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQ 375
Query: 268 ----------SSGGSSSGSSSGGSSG----GSSGGSSGNSGGSR---GDSGSESSWGSST 310
SGG G GG G G GG G GG R G G SS G +
Sbjct: 376 CNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYS 435
Query: 311 GS-SSGNHGG--SGGGNGHKPGCEKPGNEARGSG 341
G S G +GG SGGG G G G+ G G
Sbjct: 436 GDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 469
Score = 34.7 bits (78), Expect = 0.15
Identities = 24/65 (36%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD 299
G N G G GSQ G G G + G +G SSGG GG G R D
Sbjct: 168 GEDNRGYG-GSQGGGRGRGGYDKDGRGPMTG------SSGGDRGGFKNFGGHRDYGPRTD 220
Query: 300 SGSES 304
+ SES
Sbjct: 221 ADSES 225
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 80.9 bits (198), Expect = 2e-15
Identities = 68/216 (31%), Positives = 80/216 (37%), Gaps = 26/216 (12%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
ED G D + G G+ G GG G G +GG GG G G GY
Sbjct: 385 EDSRPSGGDFRGRGYGGERGYRGR----GGRG--GDRGGYGGDRSGGGYGGDRSSGGGYS 438
Query: 178 GN-SAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSG 236
G+ S G +G + G +G GG +G + G GYG R
Sbjct: 439 GDRSGGGYGGDRSGGGYGGDRGGG---YGGDRGG-----GYGGDRGGGYG--------GD 482
Query: 237 SGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
GG + GGG G G G G GD G G S G GG GG SG
Sbjct: 483 RGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYG 542
Query: 294 GGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
G G G + S G G G +GG GG G K G
Sbjct: 543 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 578
Score = 72.4 bits (176), Expect = 6e-13
Identities = 54/168 (32%), Positives = 65/168 (38%), Gaps = 16/168 (9%)
Query: 194 GQGGNGGPPN-FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
G+GG GG +G + G GYG R+S G + SG G G SGGG G
Sbjct: 407 GRGGRGGDRGGYGGDRSGG----GYGGDRSSG---GGYSGDRSGGGYGGDRSGGGYGGDR 459
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSS-GGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
G G G G GG GG GG GG G GG RG +G G
Sbjct: 460 GGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRG------GYGGDRG 513
Query: 312 SSSGNHGGSGGGNGHKP-GCEKPGNEARGSGESGIQNSETSPGMFNFD 358
G+ GG GG G ++ G G SG + S G + D
Sbjct: 514 GYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGD 561
Score = 72.0 bits (175), Expect = 8e-13
Identities = 58/188 (30%), Positives = 73/188 (38%), Gaps = 15/188 (7%)
Query: 122 RHGADAVRGSWQGVP---GHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
R G RG + G G+ G + GG+ S GG GG G GG G GY G
Sbjct: 408 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSG--GGYGGDRGGGYGG 465
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
+ G +G + G G GG+ G +G + G GYG R + G
Sbjct: 466 DRGGGYGGDRGG---GYGGDRG--GYGGDRGG-----GYGGDRGGYGGDRGGYGGDRGGY 515
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
GG GG S+ G G G G SGG S GG G GG G+ GG G
Sbjct: 516 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 575
Query: 299 DSGSESSW 306
G + +
Sbjct: 576 KMGGRNDY 583
Score = 65.5 bits (158), Expect = 8e-11
Identities = 55/194 (28%), Positives = 69/194 (35%), Gaps = 32/194 (16%)
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE--GCTNPPPS 235
G+ G G G G GG P G P G++ + +N C P P
Sbjct: 329 GSGGGRRGRGGYRGRGGFQGRGGDPKSG---DWVCPNPSCGNMNFARRNSCNQCNEPRPE 385
Query: 236 ---------------------GSGGGSSNSGGGSGSQSGSS--GSGSNGDNNNGSSSGGS 272
G GG + GG G +SG G S+G +G SGG
Sbjct: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 445
Query: 273 SSGSSSGGSSGGSSGGSSG--NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
G SGG GG GG G GG GD G +G G G+ GG GG+ G
Sbjct: 446 YGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG--GGYGGDRGGYGGDRGGGYGGDRGGYGG 503
Query: 331 EKPGNEARGSGESG 344
++ G G G
Sbjct: 504 DRGGYGGDRGGYGG 517
Score = 52.4 bits (124), Expect = 7e-07
Identities = 60/215 (27%), Positives = 79/215 (36%), Gaps = 42/215 (19%)
Query: 152 GSQGGLGGQGQ-----GNPGGLG----TPWVHGYPGNSAGSFGMNPQG-APWGQGGNGGP 201
GS G GG+ Q GNPG G + GY + S+G N G + +GQ +G
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG--------------SSNSGGG 247
++G Q Y +NQ + N SGS GG S + G
Sbjct: 65 QSYGGYENQK--QSSYSQQPYNNQGQQ-QNMESSGSQGGRAPSYDQPDYGQQDSYDQQSG 121
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS--------------GGSSGGSSGNS 293
GS SN D + S S S S + G + G G+
Sbjct: 122 YDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQ 181
Query: 294 GGSRGDSGSESSW-GSSTGSSSGNHGGSGGGNGHK 327
GG RG G + G TGSS G+ GG GH+
Sbjct: 182 GGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR 216
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/178 (30%), Positives = 69/178 (38%), Gaps = 14/178 (7%)
Query: 36 GEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG---AA 92
G+ G G G S G G + + GG G + G G G G + G+G
Sbjct: 420 GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDR--SGGGYGGDRGGGYGGDRGGGYGGDRGG 477
Query: 93 DALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFG 152
G+R G G G + G D +G D RG + G G G + GG+G G
Sbjct: 478 GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD--RGGYGGDRGGYGGDRSRGGYG--G 533
Query: 153 SQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ 209
+GG G G GG G GY G+ G +G G G GG G N N Q
Sbjct: 534 DRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYG----GDRGGYGGKMGGRNDYRNDQ 587
Score = 45.8 bits (107), Expect = 6e-05
Identities = 47/154 (30%), Positives = 51/154 (33%), Gaps = 42/154 (27%)
Query: 230 TNPPPSGSGGGSSNSGGGSGSQSGSSG-SGSNGDNNNGS--------------------- 267
T P GGGS G G G G G GD +G
Sbjct: 319 TRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQ 378
Query: 268 ----------SSGGSSSGSSSGGSSG----GSSGGSSGNSGGSR---GDSGSESSWGSST 310
SGG G GG G G GG G GG R G G SS G +
Sbjct: 379 CNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYS 438
Query: 311 GS-SSGNHGG--SGGGNGHKPGCEKPGNEARGSG 341
G S G +GG SGGG G G G+ G G
Sbjct: 439 GDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 472
Score = 34.7 bits (78), Expect = 0.15
Identities = 24/65 (36%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD 299
G N G G GSQ G G G + G +G SSGG GG G R D
Sbjct: 171 GEDNRGYG-GSQGGGRGRGGYDKDGRGPMTG------SSGGDRGGFKNFGGHRDYGPRTD 223
Query: 300 SGSES 304
+ SES
Sbjct: 224 ADSES 228
Score = 32.7 bits (73), Expect = 0.57
Identities = 35/115 (30%), Positives = 43/115 (37%), Gaps = 9/115 (7%)
Query: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
G + G G SQS SG G D SS G + SG SS G S SG S G
Sbjct: 21 GNPGSQGYGQASQS-YSGYGQTTD----SSYGQNYSGYSSYGQS--QSGYSQSYGGYENQ 73
Query: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKP--GNEARGSGESGIQNSETS 351
S S + N SG G P ++P G + +SG + S
Sbjct: 74 KQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGS 128
Score = 29.3 bits (64), Expect = 6.3
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 8/76 (10%)
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
S GS QSG + N GS G +S S SG S SG
Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG--------Y 53
Query: 304 SSWGSSTGSSSGNHGG 319
SS+G S S ++GG
Sbjct: 54 SSYGQSQSGYSQSYGG 69
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/113 (45%), Positives = 60/113 (53%), Gaps = 8/113 (7%)
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG--SSGGSSGGSSGNS 293
GSGG S+SGGG S S S GSG + G S GG GS SGG SGG SGG G+
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGG---GSISGGGYGSGGGSGGRYGSG 576
Query: 294 GGSRGDSGSESSWGSSTG---SSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
GGS+G S S +GS G S G+ GGS G G+ G + SGE+
Sbjct: 577 GGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEA 629
Score = 79.3 bits (194), Expect = 5e-15
Identities = 54/130 (41%), Positives = 64/130 (49%), Gaps = 17/130 (13%)
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
GG+GG +G+ + GY S +S + G + GSGGG S SGGG GS GS
Sbjct: 519 GGSGG--------RGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSG 570
Query: 256 GSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSG 315
G +G GGS GS SGG G S GG + GGSRG S S +GS G SS
Sbjct: 571 GRYGSG--------GGSKGGSISGGGYG-SGGGKHSSGGGSRGGSSSGGGYGSGGGGSSS 621
Query: 316 NHGGSGGGNG 325
G SG G
Sbjct: 622 VKGSSGEAFG 631
Score = 67.4 bits (163), Expect = 2e-11
Identities = 43/107 (40%), Positives = 51/107 (47%), Gaps = 5/107 (4%)
Query: 241 SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG---GSSGGSSGGSSGNSGGSR 297
SS S++ GSG G ++ G S GSSS S G GS GGS GG S + GG
Sbjct: 505 SSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYG 564
Query: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
GS +GS GS G+ SGGG G G G +RG SG
Sbjct: 565 SGGGSGGRYGSGGGSKGGSI--SGGGYGSGGGKHSSGGGSRGGSSSG 609
Score = 65.5 bits (158), Expect = 8e-11
Identities = 55/147 (37%), Positives = 65/147 (44%), Gaps = 38/147 (25%)
Query: 155 GGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQ 214
GG GG+G + GG + G+S+ G G+ G GG G +++
Sbjct: 519 GGSGGRGSSSGGGYSS-------GSSSYGSGGRQSGSRGGSGGGG-----------SISG 560
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
GYGS S G SGGGS S SGGG GS G SG G S GG
Sbjct: 561 GGYGSGGGSGGRYG--------SGGGSKGGSISGGGYGSGGGKHSSG-------GGSRGG 605
Query: 272 SSSGSSSGGSSGGSSG--GSSGNSGGS 296
SSSG G GGSS GSSG + GS
Sbjct: 606 SSSGGGYGSGGGGSSSVKGSSGEAFGS 632
Score = 62.0 bits (149), Expect = 9e-10
Identities = 57/177 (32%), Positives = 69/177 (38%), Gaps = 13/177 (7%)
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G+GG GG G ++ AV G R S + C + GGG GGG GS+
Sbjct: 11 GRGGGGGGFR-GFSSGSAVVS---GGSRRSTSSFSCLS---RHGGGGGGFGGGGFGSR-- 61
Query: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS--GGSRGDSGSESSWGSSTG 311
S G G + S G G + G GG GG G S GG G SG G G
Sbjct: 62 -SLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120
Query: 312 SSSGNHGGSGGGNG-HKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKSK 367
G GG GG G PG PG G E + S P D +N K++
Sbjct: 121 GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQ 177
Score = 56.2 bits (134), Expect = 5e-08
Identities = 45/135 (33%), Positives = 52/135 (38%), Gaps = 20/135 (14%)
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSS---------------GSGSNGDNNNGSSS---- 269
C + G GGG GS SG S G G G GS S
Sbjct: 7 CKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGL 66
Query: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG 329
GG+ S S S + GG G++G GG G G SS+G +G S G GG G G G G
Sbjct: 67 GGTKSISIS-VAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGG 125
Query: 330 CEKPGNEARGSGESG 344
PG G G
Sbjct: 126 FGGPGGVGGLGGPGG 140
Score = 53.1 bits (126), Expect = 4e-07
Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
Query: 137 GHNGAWETSGGHGIFGSQG-GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQ 195
G G +SGG GS G GG+ G+ GG G G S G G G+
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGG-------GGSISGGGYGSGGGSGGR 572
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS 255
G+GG G+ + G GYGS + + G + S SGGG + GGGS S GSS
Sbjct: 573 YGSGGGSKGGSISGG-----GYGSGGGKHSSGGGSRGG-SSSGGGYGSGGGGSSSVKGSS 626
Query: 256 G 256
G
Sbjct: 627 G 627
Score = 52.0 bits (123), Expect = 9e-07
Identities = 37/104 (35%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
Query: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR-GDSGS 302
SG S + + S S + N ++ G S G S G SSG SS SGG + G G
Sbjct: 492 SGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGG 551
Query: 303 ESSWGSSTGSSSGNHGGSGG----GNGHKPGCEKPGNEARGSGE 342
GS +G G+ GGSGG G G K G G G G+
Sbjct: 552 SGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGK 595
Score = 47.0 bits (110), Expect = 3e-05
Identities = 32/90 (35%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGG 319
+GD ++ + +SS SS +S + GGS G S G S SS S G SG+ GG
Sbjct: 492 SGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGG 551
Query: 320 SGG-----GNGHKPGCEKPGNEARGSGESG 344
SGG G G+ G G G G G
Sbjct: 552 SGGGGSISGGGYGSGGGSGGRYGSGGGSKG 581
Score = 46.6 bits (109), Expect = 4e-05
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 145 SGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ-----GAPWGQGGNG 199
+GG G FG+ GG GG+G G GG G+ G G G G P G GG G
Sbjct: 77 AGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136
Query: 200 GPPNFG 205
GP FG
Sbjct: 137 GPGGFG 142
Score = 39.3 bits (90), Expect = 0.006
Identities = 48/180 (26%), Positives = 55/180 (30%), Gaps = 37/180 (20%)
Query: 15 CLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQG 74
C G G G G + G A+ G G S + + GG G G G
Sbjct: 7 CKSRGRGG---GGGGFRGFSSGSAVVSG-GSRRSTSSFSCLSRHGGGGGG------FGGG 56
Query: 75 TREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQG 134
G G R + G G ++ V G G GR
Sbjct: 57 -----GFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGG----------------- 94
Query: 135 VPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG 194
G G GG G G G GG G G GG G P G G G G P G P G
Sbjct: 95 --GFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGP---GGVGGLGGPGGFGPGGYPGG 149
Score = 34.7 bits (78), Expect = 0.15
Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 5/54 (9%)
Query: 272 SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
S GG GG G SSG++ S G S SS+ S HGG GGG G
Sbjct: 6 SCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSF-----SCLSRHGGGGGGFG 54
Score = 34.7 bits (78), Expect = 0.15
Identities = 39/146 (26%), Positives = 53/146 (36%), Gaps = 30/146 (20%)
Query: 38 ALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGN 97
A G G S G G + G + G+ G + G G ++ G G+G+ G
Sbjct: 517 AFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGG-----GYGSGGGSGG 571
Query: 98 RVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGL 157
R G + G + + G G G G +SGG GS G
Sbjct: 572 RYGSGGGSKGGS------------------ISG---GGYGSGGGKHSSGGGSRGGSSSG- 609
Query: 158 GGQGQGNPGGLGTPWVHGYPGNSAGS 183
GG G G G G+ V G G + GS
Sbjct: 610 GGYGSG---GGGSSSVKGSSGEAFGS 632
Score = 28.9 bits (63), Expect = 8.2
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 9/87 (10%)
Query: 17 GSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSE-ALGQGT 75
GSG G + G G G G G G G G +GG GS + + G G+
Sbjct: 551 GSGGGGSISGG--------GYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGS 602
Query: 76 REAVGTGVRQVPGFGAADALGNRVGEA 102
R +G G G + ++ GEA
Sbjct: 603 RGGSSSGGGYGSGGGGSSSVKGSSGEA 629
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 80.1 bits (196), Expect = 3e-15
Identities = 68/193 (35%), Positives = 82/193 (42%), Gaps = 31/193 (16%)
Query: 130 GSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
GS +G G +G + GG+ FG GG G+G GN GG G GY G GS G
Sbjct: 211 GSQRGRGGGSGNFMGRGGN--FGGGGGNFGRG-GNFGGRG-----GYGGGGGGSRGS--- 259
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
+G GG+GG FG + PGY S G G G N GGG G
Sbjct: 260 ---YG-GGDGGYNGFGGDGGNYGGGPGYSSRGGYG-----------GGGPGYGNQGGGYG 304
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309
G G +G N G+ GG+ G + G SG N G +G S S GS
Sbjct: 305 G-----GGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSP 359
Query: 310 TGSSSGNHGGSGG 322
G G+ GGSGG
Sbjct: 360 YGGGYGSGGGSGG 372
Score = 72.0 bits (175), Expect = 8e-13
Identities = 65/196 (33%), Positives = 81/196 (41%), Gaps = 37/196 (18%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
GSQ G GG G GN G G G+FG G +G+GGN G +G
Sbjct: 211 GSQRGRGG-GSGNFMGRG------------GNFGGG--GGNFGRGGNFGG-------RGG 248
Query: 212 VAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG-SQSGSSGSGSNGDNNNGSSSG 270
G GS + +G N G GG N GGG G S G G G G N G G
Sbjct: 249 YGGGGGGSRGSYGGGDGGYN----GFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYG 304
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN--GHKP 328
G GG G + GG+ G GG+ G G+ + +G+ +G N+G GG+ G
Sbjct: 305 G------GGGYDGYNEGGNFG--GGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSS 356
Query: 329 GCEKPGNEARGSGESG 344
G G G G G
Sbjct: 357 GSPYGGGYGSGGGSGG 372
Score = 70.1 bits (170), Expect = 3e-12
Identities = 48/131 (36%), Positives = 54/131 (41%), Gaps = 14/131 (10%)
Query: 236 GSGGGSSN---SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG--GSS 290
G GGGS N GG G G+ G G N G GG S S GG GG +G G
Sbjct: 215 GRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDG 274
Query: 291 GNSGGSRGDS--GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE------ 342
GN GG G S G G G+ G +GG GG +G+ G G G G
Sbjct: 275 GNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGN 334
Query: 343 -SGIQNSETSP 352
SG Q S P
Sbjct: 335 YSGQQQSNYGP 345
Score = 65.5 bits (158), Expect = 8e-11
Identities = 44/126 (34%), Positives = 54/126 (42%), Gaps = 4/126 (3%)
Query: 237 SGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS-GGSSGGSSGGSSGNSGG 295
S G GGGSG+ G G+ G N G GG+ G GG GGS G G GG
Sbjct: 209 SAGSQRGRGGGSGNFMGRGGNFGGGGGNFGR--GGNFGGRGGYGGGGGGSRGSYGGGDGG 266
Query: 296 SRGDSGSESSWGSSTG-SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGM 354
G G ++G G SS G +GG G G G++ G G G E G G
Sbjct: 267 YNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGG 326
Query: 355 FNFDTF 360
N++ F
Sbjct: 327 GNYNDF 332
Score = 62.4 bits (150), Expect = 7e-10
Identities = 52/173 (30%), Positives = 64/173 (36%), Gaps = 23/173 (13%)
Query: 186 MNPQGAPWGQGGNGGPPNF---GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
M G+ G+GG G NF G N G G G G GG
Sbjct: 207 MQSAGSQRGRGGGSG--NFMGRGGNFGGGGGNFGRGG--------------NFGGRGGYG 250
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302
GGGS G G NG +G + GG SS GG GG G GN GG G G
Sbjct: 251 GGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPG--YGNQGGGYGGGGG 308
Query: 303 ESSWGSSTGSSSGNHGGSGGGN--GHKPGCEKPGNEARGSGESGIQNSETSPG 353
+ GN+GG G N G+ G ++ G G ++S + G
Sbjct: 309 YDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYG 361
Score = 58.2 bits (139), Expect = 1e-08
Identities = 65/212 (30%), Positives = 84/212 (39%), Gaps = 37/212 (17%)
Query: 51 VGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTG 110
V KA+ K+ +AGS+ G G+ +G G G G GN G + G G
Sbjct: 198 VKKALSKQEMQSAGSQ--RGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGG 255
Query: 111 HEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGT 170
D +G G++ G PG++ GG +G+QGG G G GG
Sbjct: 256 SRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGG----GYGGGGG--- 308
Query: 171 PWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT 230
GY N G+FG G +G GGN +FG S Q +
Sbjct: 309 --YDGY--NEGGNFG----GGNYGGGGNYN--DFG---------------NYSGQQQSNY 343
Query: 231 NPPPSGSGGGSSNS---GGGSGSQSGSSGSGS 259
P GS GG S+ GGG GS GS G GS
Sbjct: 344 GPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGS 375
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/116 (33%), Positives = 46/116 (39%), Gaps = 16/116 (13%)
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG-----GSSGGSSGNSGGSRGDSGSESS 305
QS S G G + N GG+ G GG+ G G GG G GGSRG G
Sbjct: 208 QSAGSQRGRGGGSGNFMGRGGNFGGG--GGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDG 265
Query: 306 WGSSTGSSSGNHGGS------GGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMF 355
+ G GN+GG GG G PG GN+ G G G + G F
Sbjct: 266 GYNGFGGDGGNYGGGPGYSSRGGYGGGGPGY---GNQGGGYGGGGGYDGYNEGGNF 318
Score = 42.7 bits (99), Expect = 5e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 3/85 (3%)
Query: 259 SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHG 318
S + + S G GS + GG+ GG GN G G+ G +G G S G++G
Sbjct: 203 SKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRG-GNFGGRGGYGGGGGGSRGSYG 261
Query: 319 GSGGGNGHKPGCEKPGNEARGSGES 343
G GG G GN G G S
Sbjct: 262 GGDGGYNGFGG--DGGNYGGGPGYS 284
Score = 36.2 bits (82), Expect = 0.051
Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Query: 257 SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSGGSRGDSGSESSWGSSTGSSS 314
+G N + S S S G GGS G GN GG G+ G ++G
Sbjct: 192 NGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGR----- 246
Query: 315 GNHGGSGGGN 324
G +GG GGG+
Sbjct: 247 GGYGGGGGGS 256
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 78.2 bits (191), Expect = 1e-14
Identities = 101/354 (28%), Positives = 128/354 (36%), Gaps = 36/354 (10%)
Query: 19 GEAGPL-QSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
G GP+ +G +G A G GL G + SEG G AG K S +G R
Sbjct: 998 GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEG--------PVGPAGKKGS----RGER 1045
Query: 77 EAVG-TGVRQVPG----FGAADALGNRVGEAAHA-LGNTGHEIGRQAE-DVIRHGADAVR 129
G TG +PG G A G E +G GH+ + + D G +R
Sbjct: 1046 GPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIR 1105
Query: 130 G--SWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGS 183
G G PG +GA G G+FG +G G +G G PG G P G G
Sbjct: 1106 GPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDV 1165
Query: 184 FGMNPQGAPWGQGGNGGPPNFGT-NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
M P GAP +G G + GT G V QPG + + G PP + G
Sbjct: 1166 GSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPK 1225
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDS 300
G G S +G G G S +G G G SG GS G+
Sbjct: 1226 GDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEK 1285
Query: 301 GSESS-WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
G G +SG G G PG P G G + ++ PG
Sbjct: 1286 GDPGDVGGPGPPGASGEPGAPG-----PPGKRGPSGHMGREGREGEKGAKGEPG 1334
Score = 62.8 bits (151), Expect = 5e-10
Identities = 72/259 (27%), Positives = 88/259 (33%), Gaps = 36/259 (13%)
Query: 123 HGADAVRGSWQ--GVPGHNGAWETSGGHGIFGSQGGLGGQG----------QGNPGGLGT 170
HG+ + G G PG G G G+ GS G LG G QG PG G
Sbjct: 646 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP 705
Query: 171 PWVHGYPGNSA--GSFGMNPQGAPWGQGGNGGPPNF--GTNTQGAVAQPGYGSVRASNQN 226
P GYPG G+ G G+ G G P F +G +PG R +
Sbjct: 706 P---GYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGP 762
Query: 227 EGCTNPPPSGSGGGSSNSG-GGSGSQSGSSG-------SGSNGDNNNGSSSGGSSSGSSS 278
EG P G G + G GS + G G G G + G
Sbjct: 763 EG-----PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEK 817
Query: 279 GGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPG 334
G S G G G GSRG+ G + G G+ G G K PG + P
Sbjct: 818 GKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP 877
Query: 335 NEARGSGESGIQNSETSPG 353
G G Q + PG
Sbjct: 878 GFPGPKGPPGHQGKDGRPG 896
Score = 62.8 bits (151), Expect = 5e-10
Identities = 73/274 (26%), Positives = 90/274 (32%), Gaps = 59/274 (21%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G+PG G G G G +G G QG+ G+PG G G G + + PQ
Sbjct: 863 GIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQ 922
Query: 190 G-----APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSSN 243
G P G+ G GPP G + G + +G PP P G G +
Sbjct: 923 GKTGEVGPLGERGPPGPP-------GPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGL 975
Query: 244 SG--GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSG--GSSGGSS-GGSSGNSG---- 294
G G G +G GD G + S G G +GG G SG+ G
Sbjct: 976 RGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGP 1035
Query: 295 ----GSRGDSGSESSWGSS-------------TGSSSGNHGGSG--GGNGHK-------- 327
GSRG+ G G SG G G G GHK
Sbjct: 1036 AGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGD 1095
Query: 328 ------PGCEKPGNEARGSGESGIQNSETSPGMF 355
PG P G G Q PG+F
Sbjct: 1096 AGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLF 1129
Score = 60.5 bits (145), Expect = 3e-09
Identities = 75/293 (25%), Positives = 98/293 (33%), Gaps = 28/293 (9%)
Query: 66 KVSEALGQGTREAVG-TGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHG 124
K+ G R G TG + GF L G+ G+ GH +G+ G
Sbjct: 528 KMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQR----GDFGH-VGQPGPP----G 578
Query: 125 ADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF 184
D RG+ +G PG G G G+ G +G +PG G P V G G
Sbjct: 579 EDGERGA-EGPPGPTGQAGEPGPRGLLGPRG--------SPGPTGRPGVTGIDGAPGAKG 629
Query: 185 GMNPQGAPW--GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS 242
+ P G P GQ GN G QG + PG + N G P S G
Sbjct: 630 NVGPPGEPGPPGQQGNHGSQGL-PGPQGLIGTPG---EKGPPGNPGIPGLPGSDGPLGHP 685
Query: 243 NSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302
G +G + GS G G + + G G G G +GD G
Sbjct: 686 GHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDG-FPGFKGDVGL 744
Query: 303 ESSWGSSTGSSSGNHGGSGG--GNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
+ G G G G + G E P A G+ G+ PG
Sbjct: 745 KGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPG 797
Score = 57.0 bits (136), Expect = 3e-08
Identities = 80/305 (26%), Positives = 102/305 (33%), Gaps = 35/305 (11%)
Query: 61 GAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDV 120
G AG E E GV +PG+ +G LG G E G+ +
Sbjct: 767 GQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPG-PLGPIG-EKGKSGKT- 823
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGN 179
G + G +G PG G G G G +G +G G G PG G P + G PG
Sbjct: 824 ---GQPGLEGE-RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGF 879
Query: 180 SAGSFGMNPQGAPWGQGGNGGPPNFG----TNTQGAVAQPGYGSVRASNQNEGCTNP--- 232
P+G P QG +G P + G QG PG V G P
Sbjct: 880 PG------PKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGE 933
Query: 233 --PPSGSGGGSSNSGGGSGSQSGSSGS-GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
PP G G + G+ G G G +G GG G
Sbjct: 934 RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993
Query: 290 SGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARG----S 340
G+ G G+ G G G + G GS G G P +K RG +
Sbjct: 994 KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVG--PAGKKGSRGERGPPGPT 1051
Query: 341 GESGI 345
G+ GI
Sbjct: 1052 GKDGI 1056
Score = 55.1 bits (131), Expect = 1e-07
Identities = 69/228 (30%), Positives = 81/228 (35%), Gaps = 19/228 (8%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G+PGH G G G G QG G QG G PG +G G PG + G+ G+ P
Sbjct: 494 GLPGHPG---LKGEEGAEGPQGPRGLQGPHGPPGRVGK---MGRPG-ADGARGLPGDTGP 546
Query: 193 WGQGGNGGPPNF-GTNTQ----GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG-- 245
G G G P G Q G V QPG EG P P+G G G
Sbjct: 547 KGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEG--PPGPTGQAGEPGPRGLL 604
Query: 246 GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305
G GS + G G + + G G + GS G G +G G+
Sbjct: 605 GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQG-LPGPQGLIGTPGE 663
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
G GS G GH PG E P E G G PG
Sbjct: 664 KGPPGNPGIPGLPGSDGPLGH-PGHEGPTGEKGAQGPPGSAGPPGYPG 710
Score = 52.4 bits (124), Expect = 7e-07
Identities = 49/163 (30%), Positives = 66/163 (40%), Gaps = 15/163 (9%)
Query: 122 RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNS 180
R G + +G+ +G PG +G +G G G G +G +G +G PG +G P + G PG
Sbjct: 1320 REGREGEKGA-KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQM 1378
Query: 181 AGSFGMNPQGAPWGQGGNGGPPNFG-TNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSG 238
+ P G P +G G G G + PG + G PP P G
Sbjct: 1379 GPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDP 1438
Query: 239 G-----GSSNSGGGSG-----SQSGSSGS-GSNGDNNNGSSSG 270
G GS G G Q GS GS GS G + +G
Sbjct: 1439 GPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAG 1481
Score = 46.2 bits (108), Expect = 5e-05
Identities = 66/247 (26%), Positives = 74/247 (29%), Gaps = 38/247 (15%)
Query: 124 GADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYP 177
G D +GS G+PG G G GI GS G G G G PG G P G P
Sbjct: 1250 GEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPP 1309
Query: 178 GNSAGSFGMNPQG-----------APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQN 226
G S M +G P G G GP G V G +
Sbjct: 1310 GKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMG-ARGPPGRVGPEGLRGI------ 1362
Query: 227 EGCTNPPPSGSGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGG 284
P P G G G+ G G S G GD G G
Sbjct: 1363 -----PGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEA 1417
Query: 285 SSGGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEA 337
G G G G +GD G GS G G G K PG P +
Sbjct: 1418 GEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDT 1477
Query: 338 RGSGESG 344
+G G
Sbjct: 1478 GPAGPPG 1484
Score = 45.8 bits (107), Expect = 6e-05
Identities = 61/228 (26%), Positives = 74/228 (32%), Gaps = 12/228 (5%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTPWVHGYPGNSAGSFGMNPQG 190
++G PG G G G G G G G P GL G P + G G M Q
Sbjct: 390 FEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQF 449
Query: 191 APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCT-NPPPSGSGG--GSSNSGGG 247
A G G P +F AV Q S++ G T P P G G G G
Sbjct: 450 A--GGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGA 507
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESS 305
G Q G +G G + + G G G G G G+ G
Sbjct: 508 EGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGD 567
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
+G G G G PG P +A G G+ SPG
Sbjct: 568 FGHVGQPGPPGEDGERGAEG-PPG---PTGQAGEPGPRGLLGPRGSPG 611
Score = 40.4 bits (93), Expect = 0.003
Identities = 54/202 (26%), Positives = 67/202 (33%), Gaps = 28/202 (13%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G PG G SG G G +G G +G+ G PG G G PG G G+
Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGR-VGPEGLRGI 1362
Query: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG---------- 239
P G+ G G P G + PG +G T P G G
Sbjct: 1363 PGPVGEPGLLGAP-------GQMGPPGPLGPSGLPGLKGDTG--PKGEKGHIGLIGLIGP 1413
Query: 240 -GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GS 296
G + G G G GD G G + GS G+ G G
Sbjct: 1414 PGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGP 1473
Query: 297 RGDSGSESSWGSSTGSSSGNHG 318
RGD+G G G+ + HG
Sbjct: 1474 RGDTGPAGPPG-PPGAPAELHG 1494
Score = 32.7 bits (73), Expect = 0.57
Identities = 25/78 (32%), Positives = 30/78 (38%), Gaps = 6/78 (7%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
QG+PG G G G G G +G G P G+ P G G+ M P+G
Sbjct: 1423 QGLPGVQGP---PGPKGDPGPPGPIGSLGHPGPPGVAGPL--GQKGSKGSPGSMGPRG-D 1476
Query: 193 WGQGGNGGPPNFGTNTQG 210
G G GPP G
Sbjct: 1477 TGPAGPPGPPGAPAELHG 1494
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 77.8 bits (190), Expect = 2e-14
Identities = 51/144 (35%), Positives = 59/144 (40%), Gaps = 4/144 (2%)
Query: 200 GPPNFGT--NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
G NFG N QG Q G G N G N SG G GS+ G S S G+ S
Sbjct: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
Query: 258 GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
G + G S G SG + G + G G+ GG R G S G G G+
Sbjct: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG 583
Query: 318 GG--SGGGNGHKPGCEKPGNEARG 339
GG SGGG G G G+ RG
Sbjct: 584 GGKNSGGGKGSGSGKGSDGDGERG 607
Score = 69.7 bits (169), Expect = 4e-12
Identities = 51/177 (28%), Positives = 68/177 (38%), Gaps = 14/177 (7%)
Query: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG---SSNSGGGSGSQSGSSGSG 258
PN G V+ G G+ +G GSGG +N G G+G SG G G
Sbjct: 450 PNNGARLSSEVSGSGSGNFGEEGNPQG--KEDQEGSGGDYMPMNNWGSGNGRGSGG-GQG 506
Query: 259 SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHG 318
SNG ++ SSGG+ GS GG G+ G G ++ G +G G
Sbjct: 507 SNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGG 566
Query: 319 GSGGGNGHKP--------GCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKSK 367
G G G G P G G + GSG+ + E + F K +SK
Sbjct: 567 GHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSK 623
Score = 67.0 bits (162), Expect = 3e-11
Identities = 61/185 (32%), Positives = 72/185 (38%), Gaps = 46/185 (24%)
Query: 143 ETSG-GHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
E SG G G FG +G G + Q GG P + GN GS G GQG NG
Sbjct: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGG--------GQGSNG- 509
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
QG+ S S GG+ SG G GS+ G GSN
Sbjct: 510 --------QGS----------------------SSHSSGGNQCSGEGQGSR---GGQGSN 536
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS 320
G + G+ G++ G SGG G G GS G G GS G +SG GS
Sbjct: 537 GQGSGGNQCSRDGQGTAGGHGSGG--GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGS 594
Query: 321 GGGNG 325
G G G
Sbjct: 595 GSGKG 599
Score = 65.9 bits (159), Expect = 6e-11
Identities = 54/172 (31%), Positives = 70/172 (40%), Gaps = 21/172 (12%)
Query: 157 LGGQGQGNPGGLGTPWVHGYPGNSAGSF-GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215
+ G G GN G G P S G + MN G+ G+G GG G+N QG+
Sbjct: 460 VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ---GSNGQGS---- 512
Query: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
S +S N+ C+ GG SN G G+Q G G+ G + +G GG G
Sbjct: 513 ---SSHSSGGNQ-CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG---GGQRPG 565
Query: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
G SGG G G+ G G S G +GS G+ G G K
Sbjct: 566 GGHG--SGGGQGPGDGHGSG----GGKNSGGGKGSGSGKGSDGDGERGKSLK 611
Score = 63.9 bits (154), Expect = 2e-10
Identities = 56/200 (28%), Positives = 84/200 (42%), Gaps = 21/200 (10%)
Query: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQ 116
+G +G+ E QG + G+G +P +G+ + G+ G+ ++ G++ H G
Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
Query: 117 AEDVIRHGADAVRGS-WQGVPGHNGAWE---TSGGHGIFGSQGGLGGQGQGNPGGLGTPW 172
G+ +GS QG G+ + + T+GGHG G Q GG G G GG G
Sbjct: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG--GGQG--- 575
Query: 173 VHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE----- 227
PG+ GS G G G G G G + + +G + S Q +
Sbjct: 576 ----PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPP 631
Query: 228 -GCTNPPPSGSGGGSSNSGG 246
PPP+G GG SGG
Sbjct: 632 PPPPPPPPAGGTGGKGKSGG 651
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 75.9 bits (185), Expect = 6e-14
Identities = 66/236 (27%), Positives = 86/236 (36%), Gaps = 16/236 (6%)
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL----GTPWVHGYPGNSAGSFGMN 187
+ G+ G G +G G GS G G GQ P GL G P G P + G+ G
Sbjct: 270 FSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPG-PAGARGNDGAT 328
Query: 188 PQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG 247
P G G GPP F GA + G R S +G P G++ G
Sbjct: 329 GAAGPPGPTGPAGPPGF-PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----GSRGDSGS 302
G+ G+NG + G + SG G G GNSG GS+GD+G+
Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447
Query: 303 ESSWG----SSTGSSSGNHGGSGG-GNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
+ G +G G G G G P E G G G ++ G
Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG 503
Score = 73.2 bits (178), Expect = 4e-13
Identities = 92/344 (26%), Positives = 121/344 (35%), Gaps = 52/344 (15%)
Query: 52 GKAIGKEAGGAAGSKVSEALGQGTREAVGT----GVRQVPGFGAADALGNRVGEAAHALG 107
G A + A GA G+ ++ G A G+ G++ +PG A L G+ A G
Sbjct: 692 GPAGPRGANGAPGNDGAKG-DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA-G 749
Query: 108 NTGHEIGRQAEDVIRHGADAVRGSWQ-GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPG 166
G + G +D +R + G PG G SG G G++G G +G+ P
Sbjct: 750 PKGAD-GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808
Query: 167 G----LGTPWVHGYPG--NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220
G G P G PG G G P G G GPP G V PG
Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG----PIGNVGAPGAKGA 864
Query: 221 RASNQNEGCTN----------PPPSGSGG-----GSSNSGGGSGSQSGSSGSGSNGDNNN 265
R S G T P PSG+ G G + GG G + + +G G+
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGP 924
Query: 266 GSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----------GSRGDSGSESSWGSSTGSSS 314
G + S G + G+ G G G RG+ G G S
Sbjct: 925 PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGK 984
Query: 315 GNHGGSGGGNG-----HKPGCEKPGNEARGSGESGIQNSETSPG 353
G+ G G PG P E SG G +E SPG
Sbjct: 985 QGPSGASGERGPPGPMGPPGLAGPPGE---SGREGAPGAEGSPG 1025
Score = 68.2 bits (165), Expect = 1e-11
Identities = 78/290 (26%), Positives = 100/290 (34%), Gaps = 37/290 (12%)
Query: 59 AGGAAGSKVSEALGQGTREAVGT-------GVRQVPGFGAADALGNRVGEAAHALGNTGH 111
A G AG K EA QG G G PGF GEA G G
Sbjct: 606 AVGPAG-KDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA----GKPGE 660
Query: 112 EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-------GN 164
+ D+ G RG +G PG G G G G+ G G G G
Sbjct: 661 Q--GVPGDLGAPGPSGARGE-RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717
Query: 165 PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN 224
PG G P + G PG G+ G+ P G G+ GP +GA PG VR
Sbjct: 718 PGSQGAPGLQGMPGER-GAAGLP---GPKGDRGDAGP-------KGADGSPGKDGVRGLT 766
Query: 225 QNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGG 284
G PP G G SG + G+ GD G + G
Sbjct: 767 ---GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823
Query: 285 SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334
+ G G++G ++GD+G G + + G+ G G + PG
Sbjct: 824 GAKGEPGDAG-AKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872
Score = 64.7 bits (156), Expect = 1e-10
Identities = 95/348 (27%), Positives = 121/348 (34%), Gaps = 74/348 (21%)
Query: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAE 118
A G AG++ ++ TG PGF A VG A G G + R +E
Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGA------VG----AKGEAGPQGPRGSE 364
Query: 119 DVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPG 178
G VRG G PG GA +G G G G G G PG G P G+PG
Sbjct: 365 -----GPQGVRGE-PGPPGPAGAAGPAGNPGADGQPGAKGANGA--PGIAGAP---GFPG 413
Query: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQ-GAVAQPGYGSV------------RASNQ 225
S P G P +G +G P G+ GA +PG V R +
Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARG 473
Query: 226 NEGCTN--PPPSGSGG-------------GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270
G T PP GG G G GS + GS G+ +G
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG 533
Query: 271 --GSSSGSSSGGSSG--GSSG--GSSGNSG--------GSRGDSGSESSWGSSTGSSSGN 316
G+ + S GS G G +G G +G G G+RG +G G +
Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593
Query: 317 HGGSGG-----------GNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
G G G + G + P A +GE G Q SPG
Sbjct: 594 KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG 641
Score = 63.5 bits (153), Expect = 3e-10
Identities = 66/247 (26%), Positives = 81/247 (32%), Gaps = 40/247 (16%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG----QGNPGGLGTPWVHGYPGNSAGSFGMNP 188
+GVPG GA +G G G+QG G G +G G G+P G PG
Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG---------- 647
Query: 189 QGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN---QNEGCTNPP----PSGSGGGS 241
P G G G P G + PG R G PP P G+ G
Sbjct: 648 ---PAGPPGEAGKPG-EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703
Query: 242 SNSG--------GGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNS 293
N G G GSQ G G+ G +G S G G
Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVR 763
Query: 294 G-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEARGSGESGIQ 346
G G G +G+ G S S G+ G G + PG P A G G
Sbjct: 764 GLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823
Query: 347 NSETSPG 353
++ PG
Sbjct: 824 GAKGEPG 830
Score = 61.2 bits (147), Expect = 1e-09
Identities = 65/232 (28%), Positives = 80/232 (34%), Gaps = 30/232 (12%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQG--A 191
G PG GA ++G G G G G G P G P G PG + G P+G
Sbjct: 857 GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP--PGPPGPAGKEGGKGPRGETG 914
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG--GSG 249
P G+ G GPP PG + S +G P + G + G G
Sbjct: 915 PAGRPGEVGPP----------GPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964
Query: 250 SQSGSSG----SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG-----GSRGDS 300
Q G G G +G+ SG S G G G SG G+ G
Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP 1024
Query: 301 GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSP 352
G + S G+ G G G PG P A SG+ G ET P
Sbjct: 1025 GRDGSPGAKGDRGETGPAGPPGAPG-APGAPGPVGPAGKSGDRG----ETGP 1071
Score = 60.1 bits (144), Expect = 3e-09
Identities = 62/232 (26%), Positives = 79/232 (34%), Gaps = 24/232 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFGMNPQGAP 192
G G G G G G QG G G+ G PG +G P + G PG S +G+P
Sbjct: 965 GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP 1024
Query: 193 W-----------GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGS 241
G+ G GPP GA PG + + G T P G
Sbjct: 1025 GRDGSPGAKGDRGETGPAGPPG----APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP 1080
Query: 242 SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSG 301
+ G +G Q G G+ + G G S G G SG S G +G
Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS-GPAG 1139
Query: 302 SESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
GS+ G G NG PG R +G++G PG
Sbjct: 1140 PRGPPGSAGAP------GKDGLNGLPGPIGPPGPRGR-TGDAGPVGPPGPPG 1184
Score = 58.5 bits (140), Expect = 1e-08
Identities = 85/323 (26%), Positives = 117/323 (36%), Gaps = 50/323 (15%)
Query: 59 AGGAAGSKVSEALGQ-GTREAVGT-GVRQVPGF-GAADALGNR-VGEAAHALGNTGHEIG 114
A G AG+ ++ GQ G + A G G+ PGF GA G + G GN+G
Sbjct: 381 AAGPAGNPGAD--GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP-- 436
Query: 115 RQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-GTPWV 173
GA +G G G G G G G +G G +G+ P GL G P
Sbjct: 437 ---------GAPGSKGD-TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGE 486
Query: 174 HGYPGNSA--GSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRA--------- 222
G PG+ G+ G+ P G+ G+ GP + G +PG +
Sbjct: 487 RGGPGSRGFPGADGVAGPKGPAGERGSPGPAG-PKGSPGEAGRPGEAGLPGAKGLTGSPG 545
Query: 223 SNQNEGCTNPP----------PSGSGGGSSNSG--GGSGSQSGSSGSGSNGDNNNGSSSG 270
S +G T PP P G G +G G G + + G G+ G
Sbjct: 546 SPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPG 605
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
G + G +G +G G +G +GS G + G G G
Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665
Query: 329 GCEKPG-NEARGS----GESGIQ 346
PG + ARG GE G+Q
Sbjct: 666 DLGAPGPSGARGERGFPGERGVQ 688
Score = 57.0 bits (136), Expect = 3e-08
Identities = 64/263 (24%), Positives = 94/263 (35%), Gaps = 49/263 (18%)
Query: 121 IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGN 179
+ +G D VPG G SG G+ G G G QG QG PG PG
Sbjct: 163 LSYGYDEKSTGGISVPGPMGP---SGPRGLPGPPGAPGPQGFQGPPGE---------PGE 210
Query: 180 SAGSFGMNPQGAPWGQGGNG--------------GPPNFGTNTQGAVAQPGYGSVRASNQ 225
S M P+G P G NG GPP QGA PG +
Sbjct: 211 PGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPP----GPQGARGLPGTAGLPGMKG 266
Query: 226 NEGCTNPPPSGSGGGSSNSGG--GSGSQSGSSGS----GSNGDNNNGSSSGGSSSGSSSG 279
+ G + + G + G GS ++G+ G G G+ + G + + + G
Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDG 326
Query: 280 GSSGGSSGGSSGNSG--------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCE 331
+ G +G +G G++G++G + GS G G G
Sbjct: 327 ATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAG 386
Query: 332 KPGNEARGSGESGIQNSETSPGM 354
PG G+ G + + +PG+
Sbjct: 387 NPG----ADGQPGAKGANGAPGI 405
Score = 51.2 bits (121), Expect = 2e-06
Identities = 60/242 (24%), Positives = 76/242 (31%), Gaps = 25/242 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWV-HGYPGNSAGSFGMNPQGAP 192
G PG +G G G+ G G G G GG P + +GY S G + P
Sbjct: 127 GPPGRDGI---PGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGP 183
Query: 193 WGQGGNGGPPNF--GTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGS 250
G G GPP QG +PG G PP G + G G
Sbjct: 184 SGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE 243
Query: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWG- 307
+ G+ G G SG G +G G GS G++G+ G
Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303
Query: 308 ------------SSTGSSSGNHG--GSGGGNGHKPGCEKPG--NEARGSGESGIQNSETS 351
+ GN G G+ G G PG GE+G Q S
Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363
Query: 352 PG 353
G
Sbjct: 364 EG 365
Score = 38.5 bits (88), Expect = 0.010
Identities = 30/76 (39%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHGYPGNSAGSFGMNPQ 189
G PG G SG G G G G G+ G PG +G P G G+ AG G P
Sbjct: 1124 GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD-AGPVG--PP 1180
Query: 190 GAPWGQGGNGGPPNFG 205
G P G G GPP+ G
Sbjct: 1181 GPP-GPPGPPGPPSAG 1195
Score = 35.8 bits (81), Expect = 0.067
Identities = 29/85 (34%), Positives = 32/85 (37%), Gaps = 9/85 (10%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGA 191
+G+ GH G G G GS G G G P G G P G PG G+N
Sbjct: 1105 RGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKD----GLNGLPG 1160
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPG 216
P G G P T G V PG
Sbjct: 1161 PIGPPG----PRGRTGDAGPVGPPG 1181
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 75.5 bits (184), Expect = 8e-14
Identities = 64/181 (35%), Positives = 83/181 (45%), Gaps = 16/181 (8%)
Query: 137 GHNGAWETSGGHGI-FGSQG--GLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G +G+ GG G FG G GG G G G+ GY G+ G G G
Sbjct: 195 GRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDG--- 251
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
G GG G + G+ G+ Q GYG+ + G + +G GGG GGGSGS G
Sbjct: 252 GYGGGGPGYSGGSRGYGSGGQ-GYGNQGSGYGGSGSYDSYNNGGGGGF---GGGSGSNFG 307
Query: 254 SSGSGSN-GDNNNGSSSGGSSSGSSSGGSSGGSSGG-----SSGNSGGSRGDSGSESSWG 307
GS ++ G+ NN SS+ G G + GG S G GG + + G G S S SS+G
Sbjct: 308 GGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYG 367
Query: 308 S 308
S
Sbjct: 368 S 368
Score = 71.2 bits (173), Expect = 1e-12
Identities = 67/196 (34%), Positives = 76/196 (38%), Gaps = 36/196 (18%)
Query: 154 QGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVA 213
+ G G G G GG G G GN +G G G G GG GG G G
Sbjct: 196 RSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGF---GGSRGGGGYGGS---GDGYNGFGN 249
Query: 214 QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSS 273
GYG GGG SGG G GSG G N GS GGS
Sbjct: 250 DGGYG-------------------GGGPGYSGGSRGY-----GSGGQGYGNQGSGYGGSG 285
Query: 274 SGSSSGGSSGGSSGGSSGNS---GGSRGDSGSESSWGSSTG-SSSGNHGG--SGGGNGHK 327
S S GG GG SG++ GGS D G+ ++ S+ G GN GG SG G
Sbjct: 286 SYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGG 345
Query: 328 PGCEKPGNEARGSGES 343
KP N+ G S
Sbjct: 346 QYFAKPRNQGGYGGSS 361
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 1/106 (0%)
Query: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307
S SQ G SGSG+ G G G + G S G GGS G GG G + +G
Sbjct: 190 SSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG-GGYGGSGDGYNGFG 248
Query: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353
+ G G G SGG G+ G + GN+ G G SG +S + G
Sbjct: 249 NDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGG 294
Score = 59.3 bits (142), Expect = 6e-09
Identities = 46/130 (35%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSS-GGSSSGSSSGGS---------SGGSSGGS 289
GS N GGG G G + + G N +G GGS G GGS GG GG
Sbjct: 198 GSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGG 257
Query: 290 SGNSGGSRG-DSGSE------SSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342
G SGGSRG SG + S +G S S N+GG GG G G G
Sbjct: 258 PGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGN 317
Query: 343 SGIQNSETSP 352
Q+S P
Sbjct: 318 YNNQSSNFGP 327
Score = 57.0 bits (136), Expect = 3e-08
Identities = 41/127 (32%), Positives = 52/127 (40%), Gaps = 10/127 (7%)
Query: 235 SGSGGGSSNSGGGSGSQSGS------SGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
SGSG GGG G SG G G + G GGS G + G+ GG GG
Sbjct: 197 SGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGG 256
Query: 289 SSGNSGGSRGDSGSESSWGS--STGSSSGNHGGS--GGGNGHKPGCEKPGNEARGSGESG 344
G SGGSRG +G+ S SG++ GGG G G + G
Sbjct: 257 GPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFG 316
Query: 345 IQNSETS 351
N+++S
Sbjct: 317 NYNNQSS 323
Score = 35.4 bits (80), Expect = 0.088
Identities = 24/69 (34%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 260 NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS--GSESSWGSSTGSSSGNH 317
NG N + +S+ S G SG SGN GG RG G+++ S G
Sbjct: 171 NGHNCEVRKALSKQEMASASSSQRGRSG--SGNFGGGRGGGFGGNDNFGRGGNFSGRGGF 228
Query: 318 GGSGGGNGH 326
GGS GG G+
Sbjct: 229 GGSRGGGGY 237
Score = 35.0 bits (79), Expect = 0.11
Identities = 30/87 (34%), Positives = 34/87 (39%), Gaps = 8/87 (9%)
Query: 267 SSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326
S+S S SG GG GG GN RG + S G G+ GG GG G
Sbjct: 188 SASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFS------GRGGFGGSRGG-GGYGGS 240
Query: 327 KPGCEKPGNEARGSGESGIQNSETSPG 353
G GN+ G G G S S G
Sbjct: 241 GDGYNGFGNDG-GYGGGGPGYSGGSRG 266
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 73.9 bits (180), Expect = 2e-13
Identities = 73/301 (24%), Positives = 110/301 (36%), Gaps = 36/301 (11%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSG---------NSGGSR----GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGN 335
SS GG G G+ S ++ GS++G G N H G N
Sbjct: 303 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 336 E 336
+
Sbjct: 363 Q 363
Score = 52.4 bits (124), Expect = 7e-07
Identities = 72/282 (25%), Positives = 99/282 (35%), Gaps = 36/282 (12%)
Query: 86 VPGFGAADA----LGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
VPG G A N G AA A G G GR +HG Q PG
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAGPCFDQHGG-------QQSPGMGMM 208
Query: 142 WETSGGH-GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
S G GS L +G P + GY AG G G G GG GG
Sbjct: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP-GYSRPGAGGGGGGGGGGGGGSGGGGG 267
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
G GA A + A+ +GGG GGS + G S
Sbjct: 268 GGGAGAGGAGAGAVAAAAAAAAA------------AAGGGGGGGYGGSSAGYGVLSSPRQ 315
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS---GNH 317
GG + S S ++G ++GG +G ++ SG+ + S S ++
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375
Query: 318 GGS----GGGNGHKPGCEKPGNEARGSG-ESGIQNSETSPGM 354
GGS + P +P ++A +G +G Q + G+
Sbjct: 376 GGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 73.9 bits (180), Expect = 2e-13
Identities = 73/301 (24%), Positives = 110/301 (36%), Gaps = 36/301 (11%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSG---------NSGGSR----GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGN 335
SS GG G G+ S ++ GS++G G N H G N
Sbjct: 303 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 336 E 336
+
Sbjct: 363 Q 363
Score = 52.4 bits (124), Expect = 7e-07
Identities = 72/282 (25%), Positives = 99/282 (35%), Gaps = 36/282 (12%)
Query: 86 VPGFGAADA----LGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
VPG G A N G AA A G G GR +HG Q PG
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAGPCFDQHGG-------QQSPGMGMM 208
Query: 142 WETSGGH-GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
S G GS L +G P + GY AG G G G GG GG
Sbjct: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP-GYSRPGAGGGGGGGGGGGGGSGGGGG 267
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
G GA A + A+ +GGG GGS + G S
Sbjct: 268 GGGAGAGGAGAGAVAAAAAAAAA------------AAGGGGGGGYGGSSAGYGVLSSPRQ 315
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS---GNH 317
GG + S S ++G ++GG +G ++ SG+ + S S ++
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375
Query: 318 GGS----GGGNGHKPGCEKPGNEARGSG-ESGIQNSETSPGM 354
GGS + P +P ++A +G +G Q + G+
Sbjct: 376 GGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 73.9 bits (180), Expect = 2e-13
Identities = 73/301 (24%), Positives = 110/301 (36%), Gaps = 36/301 (11%)
Query: 54 AIGKEAGGAA--GSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111
++G GGA G + + G +++ G PG L ++ G+ A G
Sbjct: 81 SLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG----PPLLSKPGDEDDAPPKMGE 136
Query: 112 EIGRQAEDVIRHGADAVRGSWQ---GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL 168
G + E H G+ Q VPG G F + G G PGG
Sbjct: 137 PAGGRYE----HPGLGALGTQQPPVAVPGGGGG---PAAVPEFNNYYGSAAPASGGPGGR 189
Query: 169 GTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG 228
P + G + GM + G G + +G Y + + N G
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEG------YPNSQC-NHYPG 242
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
+ P G GGG GGGSG G G+G+ G ++ +++ +++GG GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 289 SSG---------NSGGSR----GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGN 335
SS GG G G+ S ++ GS++G G N H G N
Sbjct: 303 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 336 E 336
+
Sbjct: 363 Q 363
Score = 52.4 bits (124), Expect = 7e-07
Identities = 72/282 (25%), Positives = 99/282 (35%), Gaps = 36/282 (12%)
Query: 86 VPGFGAADA----LGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
VPG G A N G AA A G G GR +HG Q PG
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAGPCFDQHGG-------QQSPGMGMM 208
Query: 142 WETSGGH-GIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
S G GS L +G P + GY AG G G G GG GG
Sbjct: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP-GYSRPGAGGGGGGGGGGGGGSGGGGG 267
Query: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
G GA A + A+ +GGG GGS + G S
Sbjct: 268 GGGAGAGGAGAGAVAAAAAAAAA------------AAGGGGGGGYGGSSAGYGVLSSPRQ 315
Query: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS---GNH 317
GG + S S ++G ++GG +G ++ SG+ + S S ++
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375
Query: 318 GGS----GGGNGHKPGCEKPGNEARGSG-ESGIQNSETSPGM 354
GGS + P +P ++A +G +G Q + G+
Sbjct: 376 GGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Score = 48.5 bits (114), Expect = 1e-05
Identities = 79/329 (24%), Positives = 110/329 (33%), Gaps = 31/329 (9%)
Query: 19 GEAGPLQSGEESTGTNIGEALG-HGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTRE 77
G A P G G G HG + G+ + A GA GS + L
Sbjct: 177 GSAAPASGGP---GGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSM--DPLQNSHEG 231
Query: 78 AVGTGVRQVPGF------GAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGS 131
+ PG+ G G G + G G G + A A +
Sbjct: 232 YPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
Query: 132 WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVH-GYPGNSAGSFGMNPQG 190
G G G +S G+G+ S GG PGG G + G++AG F +
Sbjct: 292 -AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGF---QRF 347
Query: 191 APWGQGGNGGPPNFGTN-TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
A Q +G P T + YG + PPPS ++ +G +G
Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
Query: 250 SQSGSSGSGSNGDNN----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS----- 300
Q ++G G D S + ++ S S G+ G + G S GS D
Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Query: 301 ----GSESSWGSSTGSSSGNHGGSGGGNG 325
G S+ S SS GGS G G
Sbjct: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPG 496
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 73.6 bits (179), Expect = 3e-13
Identities = 84/283 (29%), Positives = 113/283 (39%), Gaps = 37/283 (13%)
Query: 87 PGFGAADALGNRVGEAAHALGN------TGHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140
PGFG + N V + G G GR HG G+ G G+ G
Sbjct: 625 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-NHGGYMNAGAGYGSYGYGG 683
Query: 141 AWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
T+G + F S GG G G GG G G S+G +G QG + +
Sbjct: 684 NSATAG-YSQFYSNGGHSGNASGGGGGGG--------GGSSG-YGSYYQGDNYN---SPV 730
Query: 201 PPNFGTNTQ--GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGS 257
PP Q G +P YGS S+Q + S + SN G G Q G + G
Sbjct: 731 PPKHAGKKQPHGGQQKPSYGSGYQSHQGQ-----QQSYNQSPYSNYGPPQGKQKGYNHGQ 785
Query: 258 GSNGDNNNGSSSGGSSSGSSSGGS------SGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
GS +N+ +S GG + S SGG SGG+S SGG+ + GS +G +G
Sbjct: 786 GSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSG 845
Query: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSG-ESGIQNSETSPG 353
S G GG + + PG+ SG S Q+S+ G
Sbjct: 846 GGSSYQGKQGGYS--QSNYNSPGSGQNYSGPPSSYQSSQGGYG 886
Score = 44.3 bits (103), Expect = 2e-04
Identities = 50/160 (31%), Positives = 59/160 (36%), Gaps = 16/160 (10%)
Query: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPW--VHGYPGNSAGSFGMNPQGAPWGQ 195
H G + S G G QG Q G P GY N +P G
Sbjct: 741 HGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGG 800
Query: 196 GGNGGPPNFGTNTQGAVAQPG---YGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS---G 249
GG+ N G+ + G YGS AS NP G GG SGGGS G
Sbjct: 801 GGSDYNYESKFNYSGSGGRSGGNSYGSGGASY------NPGSHGGYGGG--SGGGSSYQG 852
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
Q G S S N + + SG SS SS G G ++ S
Sbjct: 853 KQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHS 892
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 73.6 bits (179), Expect = 3e-13
Identities = 84/283 (29%), Positives = 113/283 (39%), Gaps = 37/283 (13%)
Query: 87 PGFGAADALGNRVGEAAHALGN------TGHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140
PGFG + N V + G G GR HG G+ G G+ G
Sbjct: 621 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-NHGGYMNAGAGYGSYGYGG 679
Query: 141 AWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
T+G + F S GG G G GG G G S+G +G QG + +
Sbjct: 680 NSATAG-YSQFYSNGGHSGNASGGGGGGG--------GGSSG-YGSYYQGDNYN---SPV 726
Query: 201 PPNFGTNTQ--GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGS 257
PP Q G +P YGS S+Q + S + SN G G Q G + G
Sbjct: 727 PPKHAGKKQPHGGQQKPSYGSGYQSHQGQ-----QQSYNQSPYSNYGPPQGKQKGYNHGQ 781
Query: 258 GSNGDNNNGSSSGGSSSGSSSGGS------SGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311
GS +N+ +S GG + S SGG SGG+S SGG+ + GS +G +G
Sbjct: 782 GSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSG 841
Query: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSG-ESGIQNSETSPG 353
S G GG + + PG+ SG S Q+S+ G
Sbjct: 842 GGSSYQGKQGGYS--QSNYNSPGSGQNYSGPPSSYQSSQGGYG 882
Score = 44.3 bits (103), Expect = 2e-04
Identities = 50/160 (31%), Positives = 59/160 (36%), Gaps = 16/160 (10%)
Query: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPW--VHGYPGNSAGSFGMNPQGAPWGQ 195
H G + S G G QG Q G P GY N +P G
Sbjct: 737 HGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGG 796
Query: 196 GGNGGPPNFGTNTQGAVAQPG---YGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS---G 249
GG+ N G+ + G YGS AS NP G GG SGGGS G
Sbjct: 797 GGSDYNYESKFNYSGSGGRSGGNSYGSGGASY------NPGSHGGYGGG--SGGGSSYQG 848
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289
Q G S S N + + SG SS SS G G ++ S
Sbjct: 849 KQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHS 888
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 73.2 bits (178), Expect = 4e-13
Identities = 72/215 (33%), Positives = 77/215 (35%), Gaps = 28/215 (13%)
Query: 152 GSQGGLGGQGQGNPGGLGT-PWVHGYPGNSAGSFGMNPQGAPWGQG----GNGGPPNFGT 206
G GG G PG G P HG PG G + P P G G G P G
Sbjct: 632 GGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGP 691
Query: 207 NTQGAVAQPG-YGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN 265
G PG Y R PPP G SGGG + G G G G +
Sbjct: 692 MRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGH 751
Query: 266 GSSSG-GSSSGSSSG-----GSSGGSS---------GGSSGNSGGSRGDSGSESSWGSST 310
G G G+SSG G GG GGS G GG R G G S
Sbjct: 752 RPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG--GISG 809
Query: 311 GSSSGNHGGSGG----GNGHKPGCEKPGNEARGSG 341
GS H G GG G GH+P E PG GSG
Sbjct: 810 GSGHRPHEGPGGGMGAGGGHRPH-EGPGGSMGGSG 843
Score = 69.3 bits (168), Expect = 5e-12
Identities = 65/203 (32%), Positives = 74/203 (36%), Gaps = 33/203 (16%)
Query: 158 GGQGQGNPGGLGTPWVHGYPGNSAGSFGMNP---QGAPWGQGGNGGPPNFGTNTQGAVAQ 214
GG +G PG P+ G G P +GA G+ G GGPPN
Sbjct: 689 GGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSG-GGPPN-------GRGG 740
Query: 215 PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS--GSSGSGSNGDNNNGSSSGGS 272
PG G V P G GGG NS G + G GSG G S GG
Sbjct: 741 PGGGMVGGGGHR------PHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGG 794
Query: 273 SSGSSSGGSSGGSSGGSS-----------GNSGGSRGDSGSESSWGSSTGSSSGNHGGSG 321
G GG SGGS G GG R G S G S G G G
Sbjct: 795 GGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHG 854
Query: 322 GGNGHKPGCEKPGNEARGSGESG 344
G +GH+P + PG+ RG G
Sbjct: 855 GPHGHRPH-DVPGH--RGHDHRG 874
Score = 63.2 bits (152), Expect = 4e-10
Identities = 57/195 (29%), Positives = 66/195 (33%), Gaps = 21/195 (10%)
Query: 146 GGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG 205
GG G G GG G G GG G G G S G P P G G+G P+ G
Sbjct: 727 GGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEG 786
Query: 206 TNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN 265
PG + G + P G GGG S G + G G+ G +
Sbjct: 787 ---------PG------GSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRP 831
Query: 266 GSSSGGSSSGSS-----SGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS 320
GGS GS G GG G + G RG G HGG
Sbjct: 832 HEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGG- 890
Query: 321 GGGNGHKPGCEKPGN 335
GG GH G G+
Sbjct: 891 GGHRGHDGGHSHGGD 905
Score = 46.2 bits (108), Expect = 5e-05
Identities = 64/244 (26%), Positives = 75/244 (30%), Gaps = 57/244 (23%)
Query: 158 GGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNG-----------GPPNFGT 206
GG G G+P G G + N GS G P G GG G G PN
Sbjct: 540 GGSG-GSPDGAGGSKLPPVLANLMGSMGAGK--GPQGPGGGGINVQEILTSIMGSPNSHP 596
Query: 207 NTQGAVAQPGYGS-VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNN 265
+ + + QP Y ++ G P P +G GG G Q G G +
Sbjct: 597 SEE-LLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPH 655
Query: 266 GSSSG---------------------GSSSGSSSGGSSGGSSGG------SSGNSGGS-- 296
G G G G GG G G GG+
Sbjct: 656 GGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEP 715
Query: 297 -------RGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSE 349
RG G S G G G GG GG GH+P E PG G G S
Sbjct: 716 PPPPPPFRGARGGRSGGGPPNG-RGGPGGGMVGGGGHRPH-EGPGG---GMGNSSGHRPH 770
Query: 350 TSPG 353
PG
Sbjct: 771 EGPG 774
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/188 (27%), Positives = 63/188 (33%), Gaps = 29/188 (15%)
Query: 87 PGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSG 146
PG G G+R E G G+ G + + G GS G H G + G
Sbjct: 741 PGGGMVGGGGHRPHEGPG--GGMGNSSGHRPHE----GPGGGMGS--GHRPHEGPGGSMG 792
Query: 147 GHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWG-QGGNGG-PPNF 204
G G G GG G GG G G G G P P G GG+GG P+
Sbjct: 793 GGGGHRPHEGPGG---GISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHE 849
Query: 205 GTNTQGAVAQPGYGSVRA-------SNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
G PG+G ++ PPP G GG G + G
Sbjct: 850 G---------PGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGH 900
Query: 258 GSNGDNNN 265
GD +N
Sbjct: 901 SHGGDMSN 908
Score = 39.3 bits (90), Expect = 0.006
Identities = 37/128 (28%), Positives = 46/128 (35%), Gaps = 12/128 (9%)
Query: 36 GEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADAL 95
G ++G G G EG G I G +G + E G G +G G P G ++
Sbjct: 788 GGSMGGGGGHRPHEGPGGGIS----GGSGHRPHEGPGGG----MGAGGGHRPHEGPGGSM 839
Query: 96 GNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQG 155
G G H G G + DV H RG P H GHG G +G
Sbjct: 840 GGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGP----PPHEHRGHDGPGHGGGGHRG 895
Query: 156 GLGGQGQG 163
GG G
Sbjct: 896 HDGGHSHG 903
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 72.8 bits (177), Expect = 5e-13
Identities = 82/304 (26%), Positives = 105/304 (34%), Gaps = 34/304 (11%)
Query: 73 QGTREAVGT----GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAV 128
QG R GT G + + G D L + G A G G E G E+ G
Sbjct: 162 QGARGFPGTPGLPGFKGIRGHNGLDGLKGQPG----APGVKG-EPGAPGEN----GTPGQ 212
Query: 129 RGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP-GGLGTPWVHGYPG-----NSAG 182
G+ +G+PG G G G GS G +G G P G G P G PG + G
Sbjct: 213 TGA-RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271
Query: 183 SFGMNPQGAPWGQ------GGNGGPP-----NFGTNTQGAVAQPGYGSVRASNQNEGCTN 231
+ G P G+ G GPP N T +GA PG G
Sbjct: 272 NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPG 331
Query: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
P + G+ G G SG+ G+ + G G GS+G
Sbjct: 332 PVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAG 391
Query: 292 NSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSE 349
G G RG GS G+ + GS G +G G P +A GE G+
Sbjct: 392 PPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASG-PAGVRGPNGDAGRPGEPGLMGPR 450
Query: 350 TSPG 353
PG
Sbjct: 451 GLPG 454
Score = 70.1 bits (170), Expect = 3e-12
Identities = 98/330 (29%), Positives = 119/330 (36%), Gaps = 53/330 (16%)
Query: 47 LSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT-GVRQVPG-FGAADALGNR--VGEA 102
LS VG A G G+K + L G A G G R +PG GAA A G R VGE
Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAGL-PGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEP 348
Query: 103 AHALGNTGHEIGRQAE--------------DVIRHGADAVRGSWQGVPGHNGAWETSGGH 148
A G+ G E G + E + + G + GS G PG G + G
Sbjct: 349 GPA-GSKG-ESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS-AGPPGPPGLRGSPGSR 405
Query: 149 GIFGSQGGLGGQGQ-GNPGGLGTPWVHGYPGNSAGSFG----MNPQGAPWGQGGNGGPPN 203
G+ G+ G G G G+ G G V G P AG G M P+G P G GN GP
Sbjct: 406 GLPGADGRAGVMGPPGSRGASGPAGVRG-PNGDAGRPGEPGLMGPRGLP-GSPGNIGP-- 461
Query: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG--GGSGSQSGSSGSGSNG 261
+G V PG P P G G G G G + + G NG
Sbjct: 462 --AGKEGPVGLPGIDG-----------RPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNG 508
Query: 262 DNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGG 319
D + +G + G + G G G G +G G G S G
Sbjct: 509 DKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVG 568
Query: 320 SGGGNG-----HKPGCEKPGNEARGSGESG 344
G G PG P E GESG
Sbjct: 569 KPGERGLHGEFGLPGPAGPRGERGPPGESG 598
Score = 65.5 bits (158), Expect = 8e-11
Identities = 83/298 (27%), Positives = 111/298 (37%), Gaps = 27/298 (9%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G R PG A +G + G G + + V+ A G+PG GA
Sbjct: 589 GERGPPGESGAAGPTGPIGSRGPS-GPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGA 647
Query: 142 WETSGGHGIFGS---QGGLGGQGQ----GNPGGLGTPWVHGYPGN--SAGSFG----MNP 188
GG G G +G +G G+ G PG +G P G G+ AG+ G P
Sbjct: 648 AGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707
Query: 189 QGAPWGQGGNGGP--PNFGTNTQGAVAQPGYGSVRASNQNEGCTN-PPPSGSGGGSSNSG 245
+G+P G+ G GP PN GA QPG R + +G P+G G + +G
Sbjct: 708 RGSP-GERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAG 766
Query: 246 -GGSGSQSGSSGSGS-NGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSG 301
G +GS G G G ++G + SG S G +G G G RGD G
Sbjct: 767 PNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQG 826
Query: 302 SESSWGS----STGSSSGNHGGSG-GGNGHKPGCEKPGNEARGSGESGIQNSETSPGM 354
G +G G SG G PG P G G+ S G+
Sbjct: 827 PVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGL 884
Score = 64.3 bits (155), Expect = 2e-10
Identities = 115/420 (27%), Positives = 150/420 (35%), Gaps = 88/420 (20%)
Query: 18 SGEAGPL-------QSGEESTGTNIGE-ALGHGLGDALSEGVGKAIGKE-AGGAAGSKVS 68
SG AGP SG N GE + +G A G G+ A G G K
Sbjct: 597 SGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGK-G 655
Query: 69 EALGQGTREAVGT----GVRQVPGF----GAADALGNRVGEAAHA--------LGNTGH- 111
E G R +G G R PG G A A G+R GEA A G+ G
Sbjct: 656 EKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDR-GEAGAAGPAGPAGPRGSPGER 714
Query: 112 -EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGL-- 168
E+G + A A G G GA G +G+ G G +G G P G
Sbjct: 715 GEVGPAGPNGFAGPAGAA--GQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772
Query: 169 --------GTPWVHGYPGNSAGSFGMNPQG--------APWGQGGNGGP-----PNFGTN 207
G P + G+PG + + P G P G+ G GP P T
Sbjct: 773 PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832
Query: 208 TQGAVAQPGYGSVRASNQNEGCTNPP----PSGSGGGSSNSG-GGSGSQSGSSG-SGSNG 261
GAV PG+ + + G PP P G G G GS + G G +G+ G
Sbjct: 833 EVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG 892
Query: 262 D-------NNNGSSSGGSSSGSSSGGSSGGSSG--GSSGNSG--------GSRGDSGSES 304
+ G+ + GS + G +G G+ GN G G +G+ G
Sbjct: 893 EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952
Query: 305 SWGS-STGSSSGNHGGSG----GGNGHKPGCEKPGNEA-----RG-SGESGIQNSETSPG 353
+ G + G HG G GN + G P A RG SG GI+ + PG
Sbjct: 953 NIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012
Score = 59.7 bits (143), Expect = 4e-09
Identities = 63/235 (26%), Positives = 84/235 (35%), Gaps = 23/235 (9%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG-------QGNPGGLGTPWVHGYPGNSA--GS 183
+G PG +G G G G QGG G QG QG PG G G PG G
Sbjct: 519 RGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGE 578
Query: 184 FGM----NPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSG 236
FG+ P+G P G+ G GP ++G PG + G PSG
Sbjct: 579 FGLPGPAGPRGERGPPGESGAAGPTG-PIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSG 637
Query: 237 SGG--GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG 294
G G + G G + G G+ N G + + G + G G +G
Sbjct: 638 PSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAG 697
Query: 295 --GSRGDSGSESSWG--SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGI 345
G G +G S G G + N G +PG + GE+G+
Sbjct: 698 AAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGV 752
Score = 59.7 bits (143), Expect = 4e-09
Identities = 71/243 (29%), Positives = 85/243 (34%), Gaps = 28/243 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGT---PWVHGYPGNSAGSFGM 186
G PG G G G+ GS+G G G G PG LG P G PG + GS G+
Sbjct: 859 GTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPG-AVGSPGV 917
Query: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTN----PPPSGSGGGSS 242
N GAP G +G P N G G QPG+ R N G P P G G +
Sbjct: 918 N--GAPGEAGRDGNPGNDG--PPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAG 973
Query: 243 NSGG-GSGSQSGSSG-SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG------ 294
G G SG G +G+ G G G G G++G
Sbjct: 974 KHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPG 1033
Query: 295 --GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH--KPGCEKPGNEARGSGESGIQNSET 350
G GD G+ S G + G G +G PG P G G
Sbjct: 1034 IAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPG 1093
Query: 351 SPG 353
PG
Sbjct: 1094 PPG 1096
Score = 53.5 bits (127), Expect = 3e-07
Identities = 55/248 (22%), Positives = 86/248 (34%), Gaps = 29/248 (11%)
Query: 134 GVPGHNGAWETS-GGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGY---------PGNSAG 182
G PG G + G G+ G +G G +G PG G P G+ PG +
Sbjct: 69 GPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGP 128
Query: 183 SFGMNPQGAPWGQGGNGG--------------PPNFGTNTQGAVAQPGYGSVRASNQNEG 228
+ P G P G+ G G P G PG+ +R N +G
Sbjct: 129 AGARGPAGPP-GKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDG 187
Query: 229 CTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGG 288
P + G + G +G+ + G G+ + G + + S G G
Sbjct: 188 LKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAG 247
Query: 289 SSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
G++G G G G + G+ + G G G PG P G +G+
Sbjct: 248 PIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVG-LPGLSGPVGPPGNPGANGLT 306
Query: 347 NSETSPGM 354
++ + G+
Sbjct: 307 GAKGAAGL 314
Score = 51.2 bits (121), Expect = 2e-06
Identities = 65/258 (25%), Positives = 78/258 (30%), Gaps = 41/258 (15%)
Query: 118 EDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYP 177
E+ +R G RG G G G G G G G G P GLG + Y
Sbjct: 27 EETVRKGPAGDRGP----RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82
Query: 178 GNSAGSFGMNPQG-----APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP 232
G G G P G P G G GP F QG +PG G P
Sbjct: 83 GKGVG-LGPGPMGLMGPRGPPGAAGAPGPQGF----QGPAGEPGEPGQTGPAGARGPAGP 137
Query: 233 PPSGSGGGSSNSGGGSGSQ-----SGSSG----------SGSNGDNNNGSSSGGSSSGSS 277
P G G G + G+ G G G N G +
Sbjct: 138 PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGV 197
Query: 278 SGGSSGGSSGGSSGNSG-----------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326
G G+ G +G G+ G +G+ S GS GS G G
Sbjct: 198 KGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGF 257
Query: 327 KPGCEKPGNEARGSGESG 344
PG P E G +G
Sbjct: 258 -PGAPGPKGEIGAVGNAG 274
Score = 47.4 bits (111), Expect = 2e-05
Identities = 78/283 (27%), Positives = 97/283 (34%), Gaps = 18/283 (6%)
Query: 18 SGEAGPLQSGEESTGTNIGEALGHGL-GDALSEGVGKAIGKEAGGAAGSKVSEALGQGTR 76
+GE GP SGE T G GL G G+ + G+ V E G
Sbjct: 843 AGEKGP--SGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGI- 899
Query: 77 EAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVP 136
A G R PG + + GEA GN G++ G D + G RG + G
Sbjct: 900 -AGPPGARGPPGAVGSPGVNGAPGEAGRD-GNPGND-GPPGRDG-QPGHKGERG-YPGNI 954
Query: 137 GHNGAWETSGGHGIFGSQGGLGGQGQGNPGG-LGTPWVHGYPGNSAGSFGMNPQGAPWGQ 195
G GA G HG G G G +G+ P G +G G G S +G P +
Sbjct: 955 GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEK 1014
Query: 196 GGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPP-PSGSGGGSSNSG-----GGSG 249
G G P G N G PG G P P G G S +G G G
Sbjct: 1015 GPRGLPGLKGHN--GLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPG 1072
Query: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
+ + G G G G S GG G G+
Sbjct: 1073 TVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGD 1115
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 72.4 bits (176), Expect = 6e-13
Identities = 68/248 (27%), Positives = 86/248 (34%), Gaps = 21/248 (8%)
Query: 122 RHGADAVRGSW--QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ----GNPGGLGTPWVHG 175
R G + +G G+PG G G G G+ G +G +G G PG +G P G
Sbjct: 589 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG 648
Query: 176 YPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPS 235
PG + P G G G GPP QG PG +G PP
Sbjct: 649 PPGADGIAGAAGPPGIQ-GSPGKEGPPG----PQGPSGLPGIPGEEGKEGRDGKPGPPGE 703
Query: 236 GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG- 294
G G G++ G GD+ G S + G G +G +G
Sbjct: 704 PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP 763
Query: 295 -------GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK--PGCEKPGNEARGSGESGI 345
G G +GS S G S + GS G NG PG P GE G+
Sbjct: 764 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 823
Query: 346 QNSETSPG 353
E PG
Sbjct: 824 PGKEGVPG 831
Score = 70.5 bits (171), Expect = 2e-12
Identities = 68/223 (30%), Positives = 84/223 (37%), Gaps = 22/223 (9%)
Query: 124 GADAVRGSW-----QGVPGHNGAWETSGGHGIFGSQGGLGGQGQ-GNPGGLGTPWVHGYP 177
GAD + G+ QG PG G G G+ G G G +G+ G PG G P G P
Sbjct: 651 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 710
Query: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNP--PPS 235
G P G G +G P G + GA+ PG + + + G T P P
Sbjct: 711 GLPGPEGARGPPGFKGHTGDSGAPGPRGES--GAMGLPGQEGLPGKDGDTGPTGPQGPQG 768
Query: 236 GSGGGSSNSGGGSGSQSGSSGS----GSNGDNNNGSSSG--GSSSGSSSGGSSG--GSSG 287
G N GS + G SG+ GS G+N + G G G G G G
Sbjct: 769 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 828
Query: 288 --GSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGH 326
G G G G RGD G + G G G G GH
Sbjct: 829 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 871
Score = 62.0 bits (149), Expect = 9e-10
Identities = 93/378 (24%), Positives = 121/378 (32%), Gaps = 50/378 (13%)
Query: 4 QGPLACLLLALCLGSGEA-------GPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIG 56
Q PL +L +CL + GP E+ A G G L V
Sbjct: 147 QAPLDREVLRVCLERSASRESLDLLGPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCS 206
Query: 57 KEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV--GEAAHALGNTGHEIG 114
G G + S ALG Q P ADA + + + A L E G
Sbjct: 207 MPKG--TGHEFSAALGT-----------QGPADQRADARASCILAAKTAPGLKQLNGEPG 253
Query: 115 RQAEDVIRHGADAVRGS-----WQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLG 169
+ ED + G +RG G PG G G G G +G G QG+ G LG
Sbjct: 254 ERGEDGLP-GKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE--KGELG 310
Query: 170 TPWVHGYPGNSAGSFGMNPQGAPWGQG---------GNGGPPNFGTNTQGAVAQPGYGSV 220
P + G G + P G P G GP G +PG
Sbjct: 311 LPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG-EKGDPGLPGEPGLQGR 369
Query: 221 RASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280
+G T PP + G+ + G +G+ G+ G + S G + G
Sbjct: 370 PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 429
Query: 281 SSGGSSGGSSGNSG-----GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGN 335
G++G G G RGD G+ G G G G PG P
Sbjct: 430 DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRG-----SPGLPGPLG 484
Query: 336 EARGSGESGIQNSETSPG 353
G GI S S G
Sbjct: 485 TKGDRGAPGIPGSPGSRG 502
Score = 58.5 bits (140), Expect = 1e-08
Identities = 65/247 (26%), Positives = 83/247 (33%), Gaps = 43/247 (17%)
Query: 133 QGVPGHNGAWETSGGHGIFGSQGGLGGQG-QGNPGGLGTPWVHGYPGNSAGSFGMNPQGA 191
+GVPG G G G G +G G +G +G PGG G P G PG+ + M PQG
Sbjct: 821 KGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 880
Query: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEG---------------------CT 230
P G+ G GPP G QPG+ +R + +
Sbjct: 881 P-GENGPVGPP-------GPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLA 932
Query: 231 NPPPS--GSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG--GSS 286
PP+ S G G G +G G+ GG S G G G+
Sbjct: 933 QMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGR-PGQGGLEGPSGPIGPKGERGAK 991
Query: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQ 346
G G RG+ G G G G PG P E +G G+
Sbjct: 992 GDPGAPGVGLRGEMGPP--------GIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLP 1043
Query: 347 NSETSPG 353
PG
Sbjct: 1044 GPPGPPG 1050
Score = 57.8 bits (138), Expect = 2e-08
Identities = 60/220 (27%), Positives = 78/220 (35%), Gaps = 26/220 (11%)
Query: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
G PG G H + G G+ +G+PG G P + G PG P GA
Sbjct: 328 GPPGLPGTTSLFTPHPRMPGEQGPKGE-KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 386
Query: 194 GQGGNGGPPNFGTNTQGAVAQPGY-GSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQS 252
+G +G P GA PG G V A G + PP S G + G G +
Sbjct: 387 QEGAHGAP--------GAAGNPGAPGHVGA----PGPSGPPGSVGAPGLRGTPGKDGERG 434
Query: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSG-----GSSGNSG--GSRGDSGSESS 305
+G G G + G G G GS G G G++GD G+
Sbjct: 435 EKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGI 494
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGI 345
G S G+ G G G PG P + G G+
Sbjct: 495 PG-----SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 529
Score = 55.8 bits (133), Expect = 6e-08
Identities = 69/263 (26%), Positives = 88/263 (33%), Gaps = 40/263 (15%)
Query: 122 RHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGN-- 179
+ G +RGS PG G T G G G G G +G G G P G PG+
Sbjct: 467 KDGEPGLRGS----PGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 522
Query: 180 SAGSFGM----NPQGAPWGQGGNG---------------------GPPNFG--TNTQGAV 212
S GS G+ PQG P G+ G GPP +G
Sbjct: 523 SPGSRGLPGFPGPQG-PAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 581
Query: 213 AQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGS 272
PG + +G PP G + G G + G GD + G
Sbjct: 582 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 641
Query: 273 SSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
+ G G++G G GS G G G S G G +G KPG
Sbjct: 642 GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDG-KPG- 699
Query: 331 EKPGNEARGSGESGIQNSETSPG 353
P E +GE G+ E + G
Sbjct: 700 --PPGEPGKAGEPGLPGPEGARG 720
Score = 48.1 bits (113), Expect = 1e-05
Identities = 84/329 (25%), Positives = 104/329 (31%), Gaps = 63/329 (19%)
Query: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
G + PG L R GE G TG + E HGA G+ G PGH GA
Sbjct: 353 GEKGDPGLPGEPGLQGRPGELGPQ-GPTGPPGAKGQEGA--HGAPGAAGN-PGAPGHVGA 408
Query: 142 WETSGGHGIFGSQGGLGGQG-------------QGNPGGLG------TPWVHGYPGNSA- 181
SG G G+ G G G +G+PG +G P + G PG
Sbjct: 409 PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD 468
Query: 182 ------GSFGM----------NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225
GS G+ G P G G P G PG S
Sbjct: 469 GEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG 528
Query: 226 NEGCTNPP-PSGSGGGSSNSGGG----------SGSQSGSSG----SGSNGDNNNGSSSG 270
G P P+G G SS G + G G G GD G
Sbjct: 529 LPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 588
Query: 271 GSSSGSSSGGSSGGSSGGSSGNSG--GSRGDSGSESSWGSSTGSSSGNHGGSG----GGN 324
+ G + G G +G GS+G+ G++ G G+ G G GN
Sbjct: 589 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK--GDQGHPGVPGFMGPPGN 646
Query: 325 GHKPGCEKPGNEARGSGESGIQNSETSPG 353
PG + A G G E PG
Sbjct: 647 PGPPGADGIAGAAGPPGIQGSPGKEGPPG 675
Score = 32.0 bits (71), Expect = 0.97
Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 21/109 (19%)
Query: 112 EIGRQAED----VIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGG 167
E+G+Q E ++ A S QG PG G G G+ G G +G G+ GG
Sbjct: 918 ELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP---PGKDGLPGRAGPMGEPGRPGQGG 974
Query: 168 LGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216
L P +G G P+G +G G P G +G + PG
Sbjct: 975 LEGP---------SGPIG--PKGERGAKGDPGAP---GVGLRGEMGPPG 1009
>gi|60593038 keratin associated protein 5-4 [Homo sapiens]
Length = 288
Score = 72.4 bits (176), Expect = 6e-13
Identities = 79/227 (34%), Positives = 94/227 (41%), Gaps = 31/227 (13%)
Query: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGP---------- 201
G G GG G G GG G+ G G+ G G G G GG G
Sbjct: 2 GCCGCSGGCGSGC-GGCGSGC--GGCGSGCGGCGSGCGGCGSGCGGCGSSCCVPICCCKP 58
Query: 202 -----PNFGTNTQGAV--AQPGYGSVRASNQNEGCTNPPPSGSGGGS-SNSGGGSGSQSG 253
P ++ G+ ++ GYGS S GC + S G GS S GG GS G
Sbjct: 59 VCCCVPACSCSSCGSCGGSKGGYGSCGGSKG--GCVSCGGSKGGCGSCGGSKGGCGSCGG 116
Query: 254 SSGS-GSNGDNNNGSSSGGSSSGS--SSGGSSGG--SSGGSSG---NSGGSRGDSGSESS 305
S G GS G + G S G S G S GGS GG S GGS G + GGS+G GS
Sbjct: 117 SKGGCGSCGGSKGGCVSCGGSKGGCGSCGGSKGGCVSCGGSKGGCGSCGGSKGGCGSCGG 176
Query: 306 WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSP 352
GS G+ GG G + C KP + G G S Q+S P
Sbjct: 177 SKGGCGSCGGSKGGCGSCGCSQCSCCKPCCCSSGCGSSCCQSSCCKP 223
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.131 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,165,852
Number of Sequences: 37866
Number of extensions: 1332706
Number of successful extensions: 49062
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 941
Number of HSP's successfully gapped in prelim test: 631
Number of HSP's that attempted gapping in prelim test: 8300
Number of HSP's gapped (non-prelim): 13151
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.