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Search of human proteins with 178557734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
(776 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 1570 0.0
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 1522 0.0
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa... 597 e-170
gi|8400711 microtubule-associated protein tau isoform 3 [Homo sa... 597 e-170
gi|178557736 microtubule-associated protein tau isoform 5 [Homo ... 597 e-170
gi|8400715 microtubule-associated protein tau isoform 4 [Homo sa... 444 e-124
gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sap... 332 8e-91
gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap... 329 5e-90
gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sap... 262 1e-69
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap... 258 2e-68
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 250 3e-66
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap... 213 5e-55
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 213 7e-55
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 167 3e-41
gi|163965366 nascent polypeptide-associated complex alpha subuni... 101 3e-21
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 83 1e-15
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 83 1e-15
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 83 1e-15
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 83 1e-15
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 81 4e-15
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 78 4e-14
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 77 5e-14
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 76 1e-13
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 76 1e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 76 1e-13
gi|150378539 piccolo isoform 1 [Homo sapiens] 76 1e-13
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 75 2e-13
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 75 2e-13
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 75 2e-13
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 75 3e-13
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 1570 bits (4064), Expect = 0.0
Identities = 776/776 (100%), Positives = 776/776 (100%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA 240
GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA 240
Query: 241 QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE
Sbjct: 241 QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
Query: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA 360
FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA
Sbjct: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA 360
Query: 361 AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS
Sbjct: 361 AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
Query: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK
Sbjct: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
Query: 481 GQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
GQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT
Sbjct: 481 GQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
Query: 541 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN 600
PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN
Sbjct: 541 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN 600
Query: 601 LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 660
LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL
Sbjct: 601 LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 660
Query: 661 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 720
GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK
Sbjct: 661 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 720
Query: 721 TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 721 TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 1522 bits (3940), Expect = 0.0
Identities = 758/776 (97%), Positives = 758/776 (97%), Gaps = 18/776 (2%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA 240
GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA 240
Query: 241 QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE
Sbjct: 241 QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
Query: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA 360
FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA
Sbjct: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA 360
Query: 361 AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS
Sbjct: 361 AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
Query: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK
Sbjct: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
Query: 481 GQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
GQANATRIPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGT
Sbjct: 481 GQANATRIPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGT 522
Query: 541 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN 600
PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN
Sbjct: 523 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN 582
Query: 601 LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 660
LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL
Sbjct: 583 LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 642
Query: 661 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 720
GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK
Sbjct: 643 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 702
Query: 721 TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 703 TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
sapiens]
Length = 441
Score = 597 bits (1540), Expect = e-170
Identities = 304/349 (87%), Positives = 311/349 (89%), Gaps = 18/349 (5%)
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 111 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 170
Query: 488 IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRT 547
IPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGTPGSRSRT
Sbjct: 171 IPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGTPGSRSRT 212
Query: 548 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 607
PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG
Sbjct: 213 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 272
Query: 608 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 667
GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP
Sbjct: 273 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 332
Query: 668 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 727
GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI
Sbjct: 333 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 392
Query: 728 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 393 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
Score = 268 bits (686), Expect = 1e-71
Identities = 159/315 (50%), Positives = 179/315 (56%), Gaps = 83/315 (26%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
HVTQ R ++ GTG +D +
Sbjct: 121 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 142
Query: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
KGA GK + PG K + + R P
Sbjct: 143 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 174
Query: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 175 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 233
Query: 285 DGPSVGRAKGQDAPL 299
PS +++ Q AP+
Sbjct: 234 KSPSSAKSRLQTAPV 248
Score = 42.4 bits (98), Expect = 0.002
Identities = 62/205 (30%), Positives = 78/205 (38%), Gaps = 75/205 (36%)
Query: 329 GAPGEGPEARGPSL---GEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDG 385
GAPG+ A+ + G +EA + + + AA V Q ARMVSKSKDG
Sbjct: 83 GAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA------GHVTQ--ARMVSKSKDG 134
Query: 386 TGSDDKKAK-----------------------TSTRSSAKTL---KNRPCL--------- 410
TGSDDKKAK +TR AKT K P
Sbjct: 135 TGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDR 194
Query: 411 ----SPKHP-TPGS--------SDPLIQPSSPAVCPEPPSSPKHVSS------------- 444
SP P TPGS + P +P AV PP SP S
Sbjct: 195 SGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLK 254
Query: 445 -VTSRTGSSGAKEMKLKGADGKTKI 468
V S+ GS+ + +K + GK +I
Sbjct: 255 NVKSKIGST--ENLKHQPGGGKVQI 277
>gi|8400711 microtubule-associated protein tau isoform 3 [Homo
sapiens]
Length = 383
Score = 597 bits (1540), Expect = e-170
Identities = 304/349 (87%), Positives = 311/349 (89%), Gaps = 18/349 (5%)
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 53 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 112
Query: 488 IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRT 547
IPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGTPGSRSRT
Sbjct: 113 IPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGTPGSRSRT 154
Query: 548 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 607
PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG
Sbjct: 155 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 214
Query: 608 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 667
GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP
Sbjct: 215 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 274
Query: 668 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 727
GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI
Sbjct: 275 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 334
Query: 728 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 335 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 383
Score = 108 bits (269), Expect = 2e-23
Identities = 73/174 (41%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK-ESPLQTPTEDGSEEP 59
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK E T +E
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA 60
Query: 60 GSETSDAKSTPTAEDVTA--PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDE 117
+ A+ ++D T +GA GK A P P G + G + + +
Sbjct: 61 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG----QKGQANATRIPAK 116
Query: 118 AAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGA-PLLPEGPREATRQP 170
P SG+ + G PG G PG+ P P TR+P
Sbjct: 117 TPPAPKTPPSSGEPPKSGDRSGYSSPG-----SPGTPGSRSRTPSLPTPPTREP 165
Score = 62.0 bits (149), Expect = 2e-09
Identities = 58/216 (26%), Positives = 78/216 (36%), Gaps = 83/216 (38%)
Query: 100 GTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLL 159
G AEEAGIGDTPSLEDEAAGHVTQ
Sbjct: 42 GLKAEEAGIGDTPSLEDEAAGHVTQA---------------------------------- 67
Query: 160 PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKER-------- 211
R ++ GTG +D + KGA GK +
Sbjct: 68 ----RMVSKSKDGTGSDDKKA-----------------------KGADGKTKIATPRGAA 100
Query: 212 -PGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA-------EG 263
PG K + + R P +PP+ +P G PP++ R S PG P
Sbjct: 101 PPGQKGQANATR-----IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 155
Query: 264 AIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPL 299
++P P K + + P PS +++ Q AP+
Sbjct: 156 SLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPV 190
>gi|178557736 microtubule-associated protein tau isoform 5 [Homo
sapiens]
Length = 412
Score = 597 bits (1540), Expect = e-170
Identities = 304/349 (87%), Positives = 311/349 (89%), Gaps = 18/349 (5%)
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 82 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 141
Query: 488 IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRT 547
IPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGTPGSRSRT
Sbjct: 142 IPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGTPGSRSRT 183
Query: 548 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 607
PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG
Sbjct: 184 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 243
Query: 608 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 667
GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP
Sbjct: 244 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 303
Query: 668 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 727
GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI
Sbjct: 304 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 363
Query: 728 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 364 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
Score = 194 bits (494), Expect = 2e-49
Identities = 130/315 (41%), Positives = 150/315 (47%), Gaps = 112/315 (35%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAE AEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAE-----------------------------AEEAGIGDTPSLEDEAAG 91
Query: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
HVTQ R ++ GTG +D +
Sbjct: 92 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 113
Query: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
KGA GK + PG K + + R P
Sbjct: 114 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 145
Query: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 146 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 204
Query: 285 DGPSVGRAKGQDAPL 299
PS +++ Q AP+
Sbjct: 205 KSPSSAKSRLQTAPV 219
>gi|8400715 microtubule-associated protein tau isoform 4 [Homo
sapiens]
Length = 352
Score = 444 bits (1143), Expect = e-124
Identities = 239/350 (68%), Positives = 257/350 (73%), Gaps = 51/350 (14%)
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 53 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 112
Query: 488 IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRT 547
IPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGTPGSRSRT
Sbjct: 113 IPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGTPGSRSRT 154
Query: 548 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 607
PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG
Sbjct: 155 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 214
Query: 608 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDL-SKVTSKCGSLGNIHHK 666
GKVQI+ K +DLS V SKCGS NI H PGGG V++ + +D +V SK GSL NI H
Sbjct: 215 GKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 667 PGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAE 726
PGGG ++++ K LTFRENAKAKTDHGAE
Sbjct: 275 PGGGNKKIETHK--------------------------------LTFRENAKAKTDHGAE 302
Query: 727 IVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
IVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 303 IVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
Score = 108 bits (269), Expect = 2e-23
Identities = 73/174 (41%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK-ESPLQTPTEDGSEEP 59
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK E T +E
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA 60
Query: 60 GSETSDAKSTPTAEDVTA--PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDE 117
+ A+ ++D T +GA GK A P P G + G + + +
Sbjct: 61 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG----QKGQANATRIPAK 116
Query: 118 AAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGA-PLLPEGPREATRQP 170
P SG+ + G PG G PG+ P P TR+P
Sbjct: 117 TPPAPKTPPSSGEPPKSGDRSGYSSPG-----SPGTPGSRSRTPSLPTPPTREP 165
Score = 62.0 bits (149), Expect = 2e-09
Identities = 58/216 (26%), Positives = 78/216 (36%), Gaps = 83/216 (38%)
Query: 100 GTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLL 159
G AEEAGIGDTPSLEDEAAGHVTQ
Sbjct: 42 GLKAEEAGIGDTPSLEDEAAGHVTQA---------------------------------- 67
Query: 160 PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKER-------- 211
R ++ GTG +D + KGA GK +
Sbjct: 68 ----RMVSKSKDGTGSDDKKA-----------------------KGADGKTKIATPRGAA 100
Query: 212 -PGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA-------EG 263
PG K + + R P +PP+ +P G PP++ R S PG P
Sbjct: 101 PPGQKGQANATR-----IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 155
Query: 264 AIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPL 299
++P P K + + P PS +++ Q AP+
Sbjct: 156 SLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPV 190
>gi|87578255 microtubule-associated protein 2 isoform 4 [Homo
sapiens]
Length = 502
Score = 332 bits (851), Expect = 8e-91
Identities = 192/410 (46%), Positives = 255/410 (62%), Gaps = 36/410 (8%)
Query: 397 TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGA-- 454
T + LK +H ++ PL + + P PP SP +VT + G
Sbjct: 99 TAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESA 158
Query: 455 ------KEMKLKGADGKTK-------IATPRGAAPP--GQKGQANATRIPAKTPPAPKTP 499
K+ K K +DG TK + P PP G G + + +
Sbjct: 159 LAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSAR 218
Query: 500 PSSATKQVQRR-----PPPAGPRSER---GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 551
++ ++ ++R P P S G PP R+ PG+PGTP S RTP P
Sbjct: 219 RTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRT----PGTPGTP-SYPRTPHTP 273
Query: 552 TPPTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 606
P KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP
Sbjct: 274 GTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPK 332
Query: 607 GGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHK 666
GG+V+I+NKK+D S VQS+CGSKDNIKH GGG+VQIV K +DLS VTSKCGSL NI H+
Sbjct: 333 GGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHR 392
Query: 667 PGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAE 726
PGGG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAE
Sbjct: 393 PGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAE 452
Query: 727 IVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
I+ +SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 453 IITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 502
>gi|87578394 microtubule-associated protein 2 isoform 5 [Homo
sapiens]
Length = 559
Score = 329 bits (844), Expect = 5e-90
Identities = 205/470 (43%), Positives = 272/470 (57%), Gaps = 54/470 (11%)
Query: 343 GEDTKEADLPEPSEKQPAAAPR--GKPVSRVPQLKARMVSKSKDGTGSDDKKA-----KT 395
GE KEA + + P AA P S P + ++ G + A +
Sbjct: 108 GEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQA 167
Query: 396 STRSSAKTLKNRPCL--SPKHPTPGSSDP------------LIQPSSPAVCPEPPSSPKH 441
+ S TL P L S K P S+ P LIQP+S P S
Sbjct: 168 KDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLIQPTSAGSTDRLPYS--- 224
Query: 442 VSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPP--GQKGQANATRIPAKTPPAPKTP 499
SG K+ K + ++ + P PP G G + + +
Sbjct: 225 ---------KSGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSAR 275
Query: 500 PSSATKQVQRR-----PPPAGPRSER---GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 551
++ ++ ++R P P S G PP R+ PG+PGTP S RTP P
Sbjct: 276 RTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRT----PGTPGTP-SYPRTPHTP 330
Query: 552 TPPTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 606
P KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP
Sbjct: 331 GTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPK 389
Query: 607 GGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHK 666
GG+V+I+NKK+D S VQS+CGSKDNIKH GGG+VQIV K +DLS VTSKCGSL NI H+
Sbjct: 390 GGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHR 449
Query: 667 PGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAE 726
PGGG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAE
Sbjct: 450 PGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAE 509
Query: 727 IVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
I+ +SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 510 IITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 559
>gi|87578392 microtubule-associated protein 2 isoform 2 [Homo
sapiens]
Length = 471
Score = 262 bits (669), Expect = 1e-69
Identities = 168/410 (40%), Positives = 224/410 (54%), Gaps = 67/410 (16%)
Query: 397 TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGA-- 454
T + LK +H ++ PL + + P PP SP +VT + G
Sbjct: 99 TAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESA 158
Query: 455 ------KEMKLKGADGKTK-------IATPRGAAPP--GQKGQANATRIPAKTPPAPKTP 499
K+ K K +DG TK + P PP G G + + +
Sbjct: 159 LAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSAR 218
Query: 500 PSSATKQVQRR-----PPPAGPRSER---GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 551
++ ++ ++R P P S G PP R+ PG+PGTP S RTP P
Sbjct: 219 RTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRT----PGTPGTP-SYPRTPHTP 273
Query: 552 TPPTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 606
P KKVA++RTPPKSP++ K +L+ P+PDLK
Sbjct: 274 GTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLK----------------- 315
Query: 607 GGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHK 666
NV+SK GS DNIK+ P GG VQIV K +DLS VTSKCGSL NI H+
Sbjct: 316 --------------NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHR 361
Query: 667 PGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAE 726
PGGG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAE
Sbjct: 362 PGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAE 421
Query: 727 IVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
I+ +SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 422 IITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 471
>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
Length = 1827
Score = 258 bits (658), Expect = 2e-68
Identities = 202/599 (33%), Positives = 283/599 (47%), Gaps = 122/599 (20%)
Query: 209 KERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLP 268
+ RP +E E+ +V+E++ + P SP P + RE ++ + E
Sbjct: 1320 ERRPSPHDE--EEFEVEEAAEAQAEPKDGSP----EAPASPEREEVALSEYKTETYDDY- 1372
Query: 269 VDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFP 328
K T I S D S+ D T +E P +K +
Sbjct: 1373 -----KDETTIDDSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEK------------ 1415
Query: 329 GAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGS 388
EAR SL + KE +P RG R+ + ++ K
Sbjct: 1416 -------EARRSSLEKHRKE---------KPFKTGRG----RISTPERKVAKKEPSTVSR 1455
Query: 389 DDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSR 448
D+ + K + A+ K + P I+ + P H+S V +
Sbjct: 1456 DEVRRKKAVYKKAELAKKTEVQAHSPSRKFILKPAIKYTRPT----------HLSCVKRK 1505
Query: 449 TGSSGA---------KEMKLKGADGKTK-------IATPRGAAPP--GQKGQANATRIPA 490
T ++G K+ K K +DG TK + P PP G G +
Sbjct: 1506 TTAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSL 1565
Query: 491 KTPPAPKTPPSSATKQVQRR-----PPPAGPRSER---GEPPKSGDRSGYSSPGSPGTPG 542
+ + ++ ++ ++R P P S G PP R+ PG+PGTP
Sbjct: 1566 NSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRT----PGTPGTP- 1620
Query: 543 SRSRTPSLPTPPTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGS 597
S RTP P P KKVA++RTPPKSP++ K +L+ P+PDLK
Sbjct: 1621 SYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLK-------- 1671
Query: 598 TENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKC 657
NV+SK GS DNIK+ P GG VQIV K +DLS VTSKC
Sbjct: 1672 -----------------------NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKC 1708
Query: 658 GSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENA 717
GSL NI H+PGGG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+A
Sbjct: 1709 GSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHA 1768
Query: 718 KAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
KA+ DHGAEI+ +SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 1769 KARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 1827
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 250 bits (639), Expect = 3e-66
Identities = 188/558 (33%), Positives = 262/558 (46%), Gaps = 86/558 (15%)
Query: 253 ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312
A +P A P+P+ + T+ SE + GQ A F E
Sbjct: 573 AKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTG 632
Query: 313 KE---QAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVS 369
K+ A + L + GE ++ + + P E +P + G ++
Sbjct: 633 KKCSLPAEEDSVLEKL------GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDIT 686
Query: 370 RVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP----GSSDPLIQ 425
P + + K + + AKTST S AKT +P PK P P G + +
Sbjct: 687 TPPNKELPPSPEKKTKPLATTQPAKTST-SKAKT---QPTSLPKQPAPTTIGGLNKKPMS 742
Query: 426 PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATP-RGAAPPGQKGQAN 484
+S V PP P S+ S S K + A K A+P + A+ P + +
Sbjct: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802
Query: 485 ATRIPAKTPPAP---KTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTP 541
+T+ AKT A T PSS + P ++E G+P + + S P P
Sbjct: 803 STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE-GKPAEVKKMTAKSVPADLSRP 861
Query: 542 GSRSRT------------PSLPTPPTRE-----PKKVAVVRTPPKSPSSAK--------S 576
S S + P+ P+R P + + K P+SAK S
Sbjct: 862 KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 921
Query: 577 RLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG---------------------------- 608
RL T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 922 RLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980
Query: 609 ----------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCG 658
KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCG
Sbjct: 981 IASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCG 1040
Query: 659 SLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAK 718
S NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG KIET++LTFR NA+
Sbjct: 1041 SKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIETYRLTFRANAR 1100
Query: 719 AKTDHGAEIVYKSPVVSG 736
A+TDHGA+IV + P G
Sbjct: 1101 ARTDHGADIVSRPPHFPG 1118
>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens]
Length = 1152
Score = 213 bits (542), Expect = 5e-55
Identities = 170/529 (32%), Positives = 238/529 (44%), Gaps = 86/529 (16%)
Query: 253 ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312
A +P A P+P+ + T+ SE + GQ A F E
Sbjct: 573 AKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTG 632
Query: 313 KE---QAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVS 369
K+ A + L + GE ++ + + P E +P + G ++
Sbjct: 633 KKCSLPAEEDSVLEKL------GERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDIT 686
Query: 370 RVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP----GSSDPLIQ 425
P + + K + + AKTST S AKT +P PK P P G + +
Sbjct: 687 TPPNKELPPSPEKKTKPLATTQPAKTST-SKAKT---QPTSLPKQPAPTTIGGLNKKPMS 742
Query: 426 PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATP-RGAAPPGQKGQAN 484
+S V PP P S+ S S K + A K A+P + A+ P + +
Sbjct: 743 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSK 802
Query: 485 ATRIPAKTPPAP---KTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTP 541
+T+ AKT A T PSS + P ++E G+P + + S P P
Sbjct: 803 STQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE-GKPAEVKKMTAKSVPADLSRP 861
Query: 542 GSRSRT------------PSLPTPPTRE-----PKKVAVVRTPPKSPSSAK--------S 576
S S + P+ P+R P + + K P+SAK S
Sbjct: 862 KSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLS 921
Query: 577 RLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG---------------------------- 608
RL T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 922 RLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP 980
Query: 609 ----------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCG 658
KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCG
Sbjct: 981 IASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCG 1040
Query: 659 SLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 707
S NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 1041 SKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
Score = 140 bits (353), Expect = 4e-33
Identities = 173/663 (26%), Positives = 246/663 (37%), Gaps = 95/663 (14%)
Query: 73 EDVTAPLVDEGAPGKQAAAQPHTEIPEG-----TTAEEAGI--GDTPSLEDEAA--GHVT 123
+D PL E AP K A P TEI +T +E G+ +P E E A VT
Sbjct: 462 KDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVT 521
Query: 124 QEPESGKVV---------QEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTG 174
PE+ V+ E L E P L + G L A P +
Sbjct: 522 PPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSE 581
Query: 175 PEDTEGGRHAPELLKHQ----------LLGDLHQEGPP--------LKGAGGK-ERPGSK 215
E T E+ + Q L D+ Q P + G G K P +
Sbjct: 582 TEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEE 641
Query: 216 EEVDEDRDVDESSPQDSPPSKASP-------AQDGRPPQTAAREATSIPGFPAEGAIPLP 268
+ V E + E P +S PS+ S ++GRP + + P P + P P
Sbjct: 642 DSVLE--KLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTP--PNKELPPSP 697
Query: 269 VDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFP 328
K + + ++P S +AK Q L + P L P
Sbjct: 698 ----EKKTKPLATTQPAKTSTSKAKTQPTSLP----KQPAPTTIGGLNKKPMSLASGLVP 749
Query: 329 GAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGS 388
AP + P + + LP K A P R K S+ G+ S
Sbjct: 750 AAPPKRPAV------ASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKS 803
Query: 389 DDKKAKTST----RSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSS 444
AKT+T S+ + ++ L PK PT ++ P V
Sbjct: 804 TQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE---------------GKPAEVKK 848
Query: 445 VTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSAT 504
+T+++ + K K T G AP + P P P T P
Sbjct: 849 MTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATP--MPSRPSTTPFIDK 906
Query: 505 KQVQRRPPPAGPRSER-----GEPPKSGDRSGYSSPGS----PGTPGSRSRTPSLPTPPT 555
K +P PR R P RS S + PG ++ + T
Sbjct: 907 KPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATT 966
Query: 556 REPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL--KNVKSKIGSTENLKHQPGGGKVQII 613
R+P+ AV +T S+ K + + +++SK GS +N+KH PGGG VQI
Sbjct: 967 RKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQ 1026
Query: 614 NKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDL-SKVTSKCGSLGNIHHKPGGGQV 672
NKK+D+S V SKCGSK NIKH PGGG V+I + ++ K +K GSL N+ H P GG V
Sbjct: 1027 NKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAV 1086
Query: 673 EVK 675
+ +
Sbjct: 1087 KTE 1089
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
sapiens]
Length = 887
Score = 213 bits (541), Expect = 7e-55
Identities = 154/432 (35%), Positives = 210/432 (48%), Gaps = 77/432 (17%)
Query: 347 KEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKN 406
K A + P E +P + G ++ P + + K + + AKTST S AKT
Sbjct: 399 KSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTST-SKAKT--- 454
Query: 407 RPCLSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGA 462
+P PK P P G + + +S V PP P S+ S S K + A
Sbjct: 455 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADA 514
Query: 463 DGKTKIATP-RGAAPPGQKGQANATRIPAKTPPAP---KTPPSSATKQVQRRPPPAGPRS 518
K A+P + A+ P + + +T+ AKT A T PSS + P ++
Sbjct: 515 KAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKT 574
Query: 519 ERGEPPKSGDRSGYSSPGSPGTPGSRSRT------------PSLPTPPTRE-----PKKV 561
E G+P + + S P P S S + P+ P+R P +
Sbjct: 575 E-GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRP 633
Query: 562 AVVRTPPKSPSSAK--------SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG----- 608
+ K P+SAK SRL T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 634 STTPFIDKKPTSAKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVE 692
Query: 609 ---------------------------------KVQIINKKLDLSNVQSKCGSKDNIKHV 635
KVQI++KK+ S++QSKCGSKDNIKHV
Sbjct: 693 KKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHV 752
Query: 636 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 695
PGGG+VQI K VD+SKV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+
Sbjct: 753 PGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNV 812
Query: 696 THVPGGGNKKIE 707
H+P GG K E
Sbjct: 813 GHLPAGGAVKTE 824
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 167 bits (424), Expect = 3e-41
Identities = 126/376 (33%), Positives = 177/376 (47%), Gaps = 34/376 (9%)
Query: 347 KEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKN 406
K A + P E +P + G ++ P + + K + + AKTST S AKT
Sbjct: 399 KSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTST-SKAKT--- 454
Query: 407 RPCLSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGA 462
+P PK P P G + + +S V PP P S+ S S K + A
Sbjct: 455 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADA 514
Query: 463 DGKTKIATP-RGAAPPGQKGQANATRIPAKTPPAP---KTPPSSATKQVQRRPPPAGPRS 518
K A+P + A+ P + + +T+ AKT A T PSS + P ++
Sbjct: 515 KAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKT 574
Query: 519 ERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRL 578
E G+P + + S P P S S T KK + + SR+
Sbjct: 575 E-GKPAEVKKMTAKSVPADLSRPKSTS---------TSSMKKTTTLSGTAPAAGVVPSRV 624
Query: 579 QTAPVPMP-------DLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDN 631
+ P+P D K +K ST P ++ DL NV+SK GS +N
Sbjct: 625 KATPMPSRPSTTPFIDKKPTSAKPSSTT-----PRLSRLATNTSAPDLKNVRSKVGSTEN 679
Query: 632 IKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGS 691
IKH PGGG VQI K VD+SKV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+K+GS
Sbjct: 680 IKHQPGGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGS 739
Query: 692 LDNITHVPGGGNKKIE 707
LDN+ H+P GG K E
Sbjct: 740 LDNVGHLPAGGAVKTE 755
Score = 56.6 bits (135), Expect = 9e-08
Identities = 86/400 (21%), Positives = 146/400 (36%), Gaps = 42/400 (10%)
Query: 206 AGGKERPGSKEEVDEDRDVDESSPQD-----SPPSKASPAQDGRPPQTAAREA----TSI 256
+ G RP V D ++P + SP K P +P +T+ +A TS+
Sbjct: 400 SAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL 459
Query: 257 PGFPAEGAIP-LPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQ 315
P PA I L +S S +PA+ P P+V A+ P + ++ P +
Sbjct: 460 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK-----DVKPKPIADA 514
Query: 316 AHSEEHLGRAAFPGAPGEGPEARGPS-----LGEDTKEADLPE--PSEKQPAAAPRGKPV 368
E+ A P P P +R S + + T A + PS + P+ KP
Sbjct: 515 KAPEKR----ASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPT 570
Query: 369 SRVPQLKA----RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLI 424
+ + K +M +KS S K TS+ TL + P+ + P+
Sbjct: 571 AIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPM- 629
Query: 425 QPSSPAVCP---------EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAA 475
PS P+ P +P S+ +S + + T + K ++ K + P G
Sbjct: 630 -PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR 688
Query: 476 PPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGY-SS 534
Q + + +++ +K V+ + + S D G+ +
Sbjct: 689 VQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPA 748
Query: 535 PGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 574
G+ T G S P P PP E ++ +P+SA
Sbjct: 749 GGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 788
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 101 bits (251), Expect = 3e-21
Identities = 145/571 (25%), Positives = 183/571 (32%), Gaps = 65/571 (11%)
Query: 33 QDQEGDTDAGLKESPLQTPTEDGSE--EPGSETSDAKSTPTAEDVTAPLVDEG----APG 86
+D T + SP PT P T K TPT V P EG AP
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906
Query: 87 KQAAAQPHTEIPEGTTAEEA--GIGDTPSLEDEAAGHVTQEPE-SGKVVQEGFLREPGPP 143
+ A + P+ A A GI +PS + P G P PP
Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 144 GLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPL 203
+ G P P P+ A P+ T P +GG P +G P
Sbjct: 967 AATPPSPKGGPATP----SPKGAPTPPAAT-PPSPKGGPATPS-----------PKGAPT 1010
Query: 204 KGAGGKERPGSKEEVDEDRDVDESSPQDSPPS-KASPAQDGRPPQTAAREATSIPGFPAE 262
A P + P +PPS K SPA P A ++P P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-PKG 1069
Query: 263 GAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHL 322
G + P S GP+ KG P TP K + H
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP------PAATPPSPKGGLATPPHK 1123
Query: 323 GRAAFPGAPGEGPE---ARGPSLGEDTKEADLPEPSEKQPAAAPRGK-----PVSRVPQL 374
G P A P+ A P G T A P PS K A P K P + P
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 375 KARMVSKSKDGTGSDDKKAKTSTRS-----SAKTLKNRPCLSPKHPTPGSSDPLIQ--PS 427
K + + S G + S + S K P +P P G + P + P+
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 428 SPAVCPEPPSS------PKHVSSVTSRTGSS---GAKEMKLKGADGKTKIATPRGAAPPG 478
+PA P P PK + + T S G KGA + P P
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302
Query: 479 QKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSP 538
A PA TPP+PK P + + PP P S +G P SS G P
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP--SSKGGP 1360
Query: 539 GTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 568
TP S+ PTPP P K TPP
Sbjct: 1361 TTPSSKEG----PTPPAATPSHKGGPAMTPP 1387
Score = 92.0 bits (227), Expect = 2e-18
Identities = 155/631 (24%), Positives = 213/631 (33%), Gaps = 134/631 (21%)
Query: 46 SPLQTPTEDGSEEP----GSETSDAKSTPTAEDVTAPL---------VDEGAPGKQAAAQ 92
SP PT + P G T K PT VT P +GA AA
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 93 PHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSG 152
P + T G TP+ T G P PP + G
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPA--------ATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092
Query: 153 MPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERP 212
P P P+ A P+ T P +GG P H+ PP GG P
Sbjct: 1093 GPATP----SPKGAPMPPAAT-PPSPKGGLATPP---HKGAPTTPAATPP-SPKGGLATP 1143
Query: 213 GSKEEVDEDRDVDESSPQDSPPSK----ASPAQDGRPPQTAAREATSIPGFPAEG-AIPL 267
K ++P +PPS A+P G P AA P P G A P
Sbjct: 1144 PPKGA--------PTTPAATPPSPKGGLATPPPKGAPTTPAAT-----PPSPKGGLATPS 1190
Query: 268 PVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAF 327
P K + PA+ P P G A TP+ + AA
Sbjct: 1191 P-----KGAPTTPAATPPSPKGGLA---------------TPSPKGAPTTP------AAT 1224
Query: 328 PGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPV---SRVPQLKARMVSKSKD 384
P +P G P T A P P P+G P + P LK + +
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 385 GTGSDDKKAKTSTR-----SSAKTLKNRPCLSPKHP--TPGSSDPLIQPSSPAVCPEPPS 437
G + S + S K P +P P +PG+ P P+ PAV P
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP--- 1341
Query: 438 SPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 497
SPK ++ + T SS +G T AA P KG PA TPP+PK
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTP-----PAATPSHKGG------PAMTPPSPK 1390
Query: 498 TPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSP---------------------- 535
P+ + + P P S + P R G ++P
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
Query: 536 ---GSPGTPGSRSRTPSLP--TPPTRE----PKKVAVVRTPPKSPSS-AKSRLQTAPVPM 585
G P TP S+ P+LP TPP+ + PK+VA +P K+P++ A T P +
Sbjct: 1451 APKGGPATPSSKG-DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
Query: 586 PDLKNVKSKIGSTENLKHQPGGGKVQIINKK 616
P + ++ +T + + P +++KK
Sbjct: 1510 P---SSPKEVPATPSSRRDPIAPTATLLSKK 1537
Score = 84.0 bits (206), Expect = 5e-16
Identities = 136/596 (22%), Positives = 197/596 (33%), Gaps = 109/596 (18%)
Query: 38 DTDAGLKESPLQTPTE-----DGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ 92
D+ L +S L TPT + ++ G + AK T T +P ++ G + A
Sbjct: 630 DSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLE----GTVSLAP 685
Query: 93 PHTEIPEGT---------TAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPP 143
+ + EGT +E + +P + PE K V L G P
Sbjct: 686 KNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP 745
Query: 144 GLSHQLMSGMPGAPLLP--EGPREATRQPSGTGPEDTEGGRHAPELLKHQLLG----DLH 197
+ ++ + L P P+E + SG + G LG
Sbjct: 746 PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQT 805
Query: 198 QEGPPLKGAGGKERP------------------------GSKEEVDEDRDVDESSPQDSP 233
+ P KG+ G + P GSK+ SP+ +P
Sbjct: 806 KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865
Query: 234 -PSKASPAQDGR----PPQTAAREATSIPGFPAEG-AIPLPVDFLSKVSTEIPASEPDGP 287
PS +P P +T ++P FP EG A P P + PA
Sbjct: 866 TPSAVTPLSPKGVTLPPKETPTPSVVNLP-FPKEGPATPAP--------KQAPALSMTSS 916
Query: 288 SVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTK 347
S +A+ AP + + AA P +P GP P
Sbjct: 917 SPKKARATPAP----------KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 348 EADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNR 407
A P P +P+G P P K T S K A T + + K
Sbjct: 967 AATPPSPKGGPATPSPKGAPT---PPAATPPSPKGGPATPSP-KGAPTPPAVTPPSPKGS 1022
Query: 408 PCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTK 467
P +P P S+ P P SP P PK + + T
Sbjct: 1023 PAATP-FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT------------------ 1063
Query: 468 IATPRGA-APPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKS 526
+ +P+G A P KG A PA TPP+PK P++ + + PP A P S +G
Sbjct: 1064 LPSPKGGPATPSLKG---APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG----- 1115
Query: 527 GDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP 582
G ++P G P + + TP P P TP +P S K L T P
Sbjct: 1116 ----GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Score = 82.8 bits (203), Expect = 1e-15
Identities = 156/622 (25%), Positives = 218/622 (35%), Gaps = 110/622 (17%)
Query: 42 GLKESPLQTPT--EDGSEEP---GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH-- 94
G +P TP + G P G+ T+ A + P+ + A +GAP AA P
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 95 ----TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLM 150
T P+G A PSL+ G + P G + P P G
Sbjct: 1253 GGPATPPPKGAPTPPAAT--PPSLK----GGLATPPHKG-APNPAVVTPPSPKG--GPAT 1303
Query: 151 SGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKE 210
S GAP P + + GT P +G P + G GG
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPP--KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 211 RPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIP-GFPAEGAIPLPV 269
P SKE + P +P K PA PP A P G P A+ +P+
Sbjct: 1362 TPSSKE--------GPTPPAATPSHKGGPAMT--PPSPKRGPAIPSPKGDPTSPAV-IPL 1410
Query: 270 DFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPG 329
+T + PS G ++TP A + L +A
Sbjct: 1411 SPKKAPATPVTREGAATPSKG---------------DLTP-----PAVTPVSLKKAPATS 1450
Query: 330 APGEGPEARGPSLGEDTKEADLPEPSEKQPAA--------APRGKPVSRVPQ----LKAR 377
AP GP A S G+ T A P PS K+P A +P+ P + P L A
Sbjct: 1451 APKGGP-ATPSSKGDPTLPAVTP-PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508
Query: 378 MVSKSKDGTGSDDKK----AKTSTRSSAKT---LKNRPCLSPKHPTPGSSDPLIQPSSPA 430
+ S K+ + + A T+T S KT L + L P T S +P
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568
Query: 431 VCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPA 490
P PSS K SS + T S+ KGA ++ P P K A PA
Sbjct: 1569 EAPATPSS-KEASSPPAVTPST------YKGAPSPKELLIPPAVTSPSPK---EAPTPPA 1618
Query: 491 KTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPP-------KSGDRSGYSSPGSPGTPG- 542
TPP+P+ P++ + PP P S + P K G +S G P G
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Query: 543 ----------SRSRTPSLPTPPTREP--KKVAVVRTP----PKSPSSAKSRLQT-APVPM 585
+ TP + P + P KK + P P + + +K L T AP P+
Sbjct: 1679 TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL 1738
Query: 586 PDLKNVKSKIGSTENLKHQPGG 607
++ SK ++ H P G
Sbjct: 1739 LPVQKDSSKTAKGKDASHSPKG 1760
Score = 70.1 bits (170), Expect = 7e-12
Identities = 137/578 (23%), Positives = 200/578 (34%), Gaps = 80/578 (13%)
Query: 26 QGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEE---PGSETSDAKSTPTAEDVTAPLVDE 82
+GG T +EG T P TP+ G P + A +P D T+P V
Sbjct: 1357 KGGPTTPSSKEGPTP------PAATPSHKGGPAMTPPSPKRGPAIPSPKG-DPTSPAVIP 1409
Query: 83 GAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA--GHVTQEPESGKVVQEGFLREP 140
+P K+A A P T EG G P++ + T P+ G
Sbjct: 1410 LSP-KKAPATPVTR--EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS----K 1462
Query: 141 GPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEG 200
G P L + P +P P P++ S T AP L
Sbjct: 1463 GDPTLP----AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL------------- 1505
Query: 201 PPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFP 260
P + + KE P + D +P + SK +PA P + A ++P
Sbjct: 1506 PAVIPSSPKEVPATPSSRR-----DPIAPTATLLSKKTPATLA-PKEALIPPAMTVPSPK 1559
Query: 261 AEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEE 320
AIP P + + S++ AS P + KG +P E +T KE
Sbjct: 1560 KTPAIPTPKEAPATPSSK-EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP- 1617
Query: 321 HLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVS 380
A P +P +GP P G T P + P + P S ++ A +
Sbjct: 1618 ----AVTPPSPEKGPATPAPK-GTPTSPPVTPSSLKDSPTS-----PASVTCKMGATVPQ 1667
Query: 381 KSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSS---PAVCPEPPS 437
SK G KK T+ + + P +P P P + SS P +CP+P +
Sbjct: 1668 ASK---GLPAKKGPTALKEVL--VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722
Query: 438 S--PKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA 495
K S + ++ K A GK +P+G P + + A
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782
Query: 496 PKTPPSSATKQVQRRPP---PAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT 552
PK P SA+ PP P P PPK P +PG +PS P
Sbjct: 1783 PK--PESASVSAAPSPPVSLPLAPSPVPTLPPKQ--------QFLPSSPGLVLESPSKPL 1832
Query: 553 PPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKN 590
P E + + ++ P P S Q+ V MP K+
Sbjct: 1833 APADEDELLPLI---PPEPISGGVPFQSVLVNMPTPKS 1867
Score = 69.7 bits (169), Expect = 1e-11
Identities = 106/436 (24%), Positives = 154/436 (35%), Gaps = 61/436 (13%)
Query: 159 LPEGPREATRQPSGTGPEDTEGGRH----APELLKHQLLGDLHQEGPPLKGAGGKERPGS 214
LP P + P P++T APE+ K L G P PG+
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP---------PGT 748
Query: 215 KEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
K+ VD +P S P K P +D TA+ + T + A+ PL V +
Sbjct: 749 KK-VDGISHTSALAPVASSP-KECPTEDSGASATASSKGTLT--YLADSPSPLGVSVSPQ 804
Query: 275 VS---TEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAP 331
T+ ++ PD P +G +P+E +F E +F G+
Sbjct: 805 TKRPPTKKGSAGPDTP-IGNLSSPVSPVEASFLPE----------------NSLSFQGSK 847
Query: 332 GEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK--PVSRVPQLKARMVSKSKDGTGSD 389
P+ P PS P + P+G P P + K+G +
Sbjct: 848 DSPATTHSPT---PPSPKGAPTPSAVTPLS-PKGVTLPPKETPTPSVVNLPFPKEGPATP 903
Query: 390 -DKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSR 448
K+A + +S+ K R +PK P S P P+ PA P P S
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKG-IPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 449 TGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQ 508
A KG G A P KG A PA TPP+PK P++ + +
Sbjct: 963 PTPPAATPPSPKG-----------GPATPSPKG---APTPPAATPPSPKGGPATPSPKGA 1008
Query: 509 RRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPP 568
PP P S +G P + G S+P + P + + P P A + +P
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
Query: 569 KSPSSAKSRLQTAPVP 584
P A L+ AP P
Sbjct: 1069 GGP--ATPSLKGAPTP 1082
Score = 36.2 bits (82), Expect = 0.12
Identities = 78/387 (20%), Positives = 130/387 (33%), Gaps = 45/387 (11%)
Query: 228 SPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIP------- 280
+PQ P S A+ A P T A +P + LP+ + T +P
Sbjct: 52 APQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPI 111
Query: 281 -------ASEPDGPSVGRAKGQDAPLEFTFHVEITP-NVQKEQAHSEEHLGRAAFPGAPG 332
AS P++ APL V + P +VQK A L
Sbjct: 112 SPAALALASPMIAPTLKGTPSSSAPLAL---VALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Query: 333 EGP--EARGPSLGEDTKEADLPEPSEKQPAAAPRGKP-----VSRVPQLKARMVSKSKDG 385
G P + K PSE P P+G P VS VP ++ + G
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVP--NPKGTPSPPCIVSTVPYHCVTPMASIQSG 226
Query: 386 TGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSP-AVCPEPPSSPKHVSS 444
S + T+T + A SP+ S LI P +P ++ + P SP S
Sbjct: 227 VASLPQTTPTTTLAIA---------SPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALS 277
Query: 445 VTSRTGSSGAKEMKLKGADGKTKIATPRGA-APPGQKGQANATRIPAKTPPAPKTPPSSA 503
+++++ K G + G+ P + + ++ +T P+ + P+
Sbjct: 278 LSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVK 337
Query: 504 TKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAV 563
T V A S+R P R+ P + + P + + P ++
Sbjct: 338 TISVDHSSTGASYPSQRSVIPPLPSRNEV-------VPATVAAFPVVAPSVDKGPSTISS 390
Query: 564 VRTPPKSPSSAKSRLQTAPVPMPDLKN 590
+ P + + +P LK+
Sbjct: 391 ITCSPSGSLNVATSFSLSPTTSLILKS 417
Score = 35.0 bits (79), Expect = 0.27
Identities = 49/196 (25%), Positives = 75/196 (38%), Gaps = 16/196 (8%)
Query: 395 TSTRSSAKTLKNRPCLSPKHPTPGSSDPL--IQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
T + T + C+SP P SS P+ I+P+SPA P +PK S+ + T
Sbjct: 448 TIAAAPTTTFEVATCVSP----PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRI 503
Query: 453 GAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPP 512
D K ++ P Q + +PA AP +P + ++ P
Sbjct: 504 PVSPPLPDPEDLKNLPSSVLVKFPT----QKDLQTVPASLEGAPFSPAQAGL--TTKKDP 557
Query: 513 PAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP-PTREPKKVAVVRTPPKSP 571
P + +S SSP P +P + SL P P +P A T P
Sbjct: 558 TVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP---ASSMTSPLGV 614
Query: 572 SSAKSRLQTAPVPMPD 587
+S+ S ++T PD
Sbjct: 615 NSSASVIKTDSYAGPD 630
Score = 33.5 bits (75), Expect = 0.77
Identities = 42/158 (26%), Positives = 63/158 (39%), Gaps = 6/158 (3%)
Query: 481 GQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
GQ T +P PAP+ P SA Q P P+ S E P SG + P
Sbjct: 39 GQPGPT-LPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGT-A 96
Query: 541 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL--KNVKSKIGST 598
P + + P+L PP P +A+ +P +P+ + +AP+ + L +V+
Sbjct: 97 PEAPTFLPNLIGPPI-SPAALALA-SPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFP 154
Query: 599 ENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVP 636
NL P V + LS + K N+ VP
Sbjct: 155 PNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVP 192
Score = 32.7 bits (73), Expect = 1.3
Identities = 54/209 (25%), Positives = 69/209 (33%), Gaps = 36/209 (17%)
Query: 53 EDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTP 112
++GS+ P S + A P +D + + A GK A+ P +G A TP
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSS-----KTAKGKDASHSP-----KGPLAPPESKASTP 1772
Query: 113 SLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP----LLPEGPREATR 168
L A V +PES V P PP S +P P LP P
Sbjct: 1773 -LTAAAFEKVLPKPESASVSAA-----PSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE 1826
Query: 169 QPSGT-------------GPEDTEGGRHAPELLKHQLL---GDLHQEGPPLKGAGGKERP 212
PS PE GG +L + + P K K
Sbjct: 1827 SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNK 1886
Query: 213 GSKEEVDEDRDVDESSPQDSPPSKASPAQ 241
GS E D D V E QDS + AQ
Sbjct: 1887 GSGTESDSDESVPELEEQDSTQATTQQAQ 1915
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 82.8 bits (203), Expect = 1e-15
Identities = 136/583 (23%), Positives = 206/583 (35%), Gaps = 67/583 (11%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQE-PESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
T +E P+ E A T+ P + K ++P P + P
Sbjct: 274 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329
Query: 160 PEGPREATRQPSGTGPED---TEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
P+ P T++P+ T P++ T + AP K P + P + +
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----------PAPTTPKEPAPTTTK 378
Query: 217 EVDEDRDVDESSPQDSPPS--KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
E ++P++ P+ K++P P T + A + P P+ P K
Sbjct: 379 EPSP------TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432
Query: 275 VSTEIPASEPDGPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFPGAPG 332
+P P+ + P E T + P KE A + + P P
Sbjct: 433 EPAPTTPKKP-APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP---KETAPTTPK 488
Query: 333 EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKK 392
+ L T E P E+ P +P P+ A K+ + +
Sbjct: 489 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPAPTTPKAA-APNTPKEP 546
Query: 393 AKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTS 447
A T+ + A T P +PK P G++ ++ +P +P +PK ++ T+
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTT 604
Query: 448 RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQV 507
+ +S + K TP+G AP K A T PAP TP +A +
Sbjct: 605 KEPTSTTCD--------KPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTPKGTAPTTL 652
Query: 508 QRRPPPAGPR----SERGEPPKSGDRSGYSSPGSPGTPGSRS-RTPSLPTPPTREPKKVA 562
+ P P P+ E G S S +P TP + TP P P T PKK A
Sbjct: 653 -KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--PKKPA 709
Query: 563 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 605
T P++P S + T KS ST L +P
Sbjct: 710 --PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 750
Score = 82.4 bits (202), Expect = 1e-15
Identities = 133/588 (22%), Positives = 200/588 (34%), Gaps = 66/588 (11%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 319
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
TT +E TP+ E A T+EP +EP P + AP
Sbjct: 320 TTPKEP----TPTTPKEPAP-TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTT 368
Query: 160 PEGPREAT-RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P+ P T ++PS T P++ AP K K A + S
Sbjct: 369 PKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI------PGFPAEGAIPLPVDFL 272
E P + P K +P P T +E P P E A P +
Sbjct: 424 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483
Query: 273 SKVSTEIPASEPD--GPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFP 328
++ + P+ P+ P E T E TP +E A + +AA P
Sbjct: 484 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAP 540
Query: 329 GAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK------------PVSRVPQLKA 376
P E T + P ++ P+G P P+ A
Sbjct: 541 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 600
Query: 377 RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAV 431
+K T + DK A T+ + +A T P +PK P P G++ ++ +P
Sbjct: 601 PTTTKEPTST-TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659
Query: 432 CPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT-RIPA 490
+P +PK ++ T++ +S + +T TP+ AP K A T P
Sbjct: 660 PKKP--APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 717
Query: 491 KTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSL 550
T TP ++ + P EP + PG P T + P +
Sbjct: 718 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 777
Query: 551 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 598
T + + + TP + ++ K +TA K +SKI +T
Sbjct: 778 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE---KTTESKITAT 822
Score = 62.0 bits (149), Expect = 2e-09
Identities = 55/235 (23%), Positives = 90/235 (38%), Gaps = 17/235 (7%)
Query: 353 EPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSP 412
E + K PA +P P+ A + K+ T + K A T+ + A T +P
Sbjct: 202 ETTTKGPALTTPKEPTPTTPKEPAS--TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 259
Query: 413 KHPTPGSSDPLIQPSSPAVCPEP-PSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATP 471
K P P ++ + +P EP P++ K + T+++ + KE TP
Sbjct: 260 KEPAPTTT----KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE---------PAPTTP 306
Query: 472 RGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSG 531
+ AP K A T TP PK P + + P P + + P +
Sbjct: 307 KKPAPTTPKEPAPTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365
Query: 532 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
++P P ++ +P+ P P K A T +P++ KS T P P
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 420
Score = 57.0 bits (136), Expect = 7e-08
Identities = 123/594 (20%), Positives = 194/594 (32%), Gaps = 112/594 (18%)
Query: 50 TPTEDGSEEPG--SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAG 107
TP E P + T+ K TPT + AP P K A P P TT EE
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT----PEKPAPTTPEELAP--TTPEEP- 522
Query: 108 IGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT 167
TP+ +E A P + K +EP AP P+ P T
Sbjct: 523 ---TPTTPEEPA------PTTPKAAAPNTPKEP---------------APTTPKEPAPTT 558
Query: 168 -RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDE 226
++P+ T P++T AP K L + P ++P KE
Sbjct: 559 PKEPAPTTPKET-----APTTPKGTAPTTLKEPAPTTP-----KKPAPKELAPTTTKEPT 608
Query: 227 SSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA----EGAIPLPVDFLSKVSTEIPAS 282
S+ D P A G P T A + P PA +G P + + + + PA
Sbjct: 609 STTCDKP---APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 665
Query: 283 EPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEG-PEARGPS 341
+ P+ KG + T + P KE A + P P PE P+
Sbjct: 666 KELAPTT--TKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 719
Query: 342 LGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSA 401
E + EP+ + P P+L A K+ + + + T T ++
Sbjct: 720 TSEVSTPTTTKEPTTIHKS------PDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 773
Query: 402 KTLKNRPCLSPKHPTPGSSDPLIQP--SSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKL 459
K P+ T + ++P P K ++ T +T S
Sbjct: 774 K---------PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 824
Query: 460 KGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSE 519
+ T+ TP + + P T + T ++ +P
Sbjct: 825 QVTSTTTQDTTPF---------KITTLKTTTLAPKVTTTKKTITTTEIMNKPE------- 868
Query: 520 RGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP--------PKSP 571
E K DR+ S++ TP P PT+ PKK + P PK+
Sbjct: 869 --ETAKPKDRA----------TNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTT 915
Query: 572 SSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 625
+ + T P P + ++ + +T P V++ K D + +
Sbjct: 916 PTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 969
Score = 52.8 bits (125), Expect = 1e-06
Identities = 53/217 (24%), Positives = 84/217 (38%), Gaps = 17/217 (7%)
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT--PGSSDPLIQPSSPAVCPEPPSSPKHV 442
G+G D+ K +T ++ T N+ SPK T P + P + P+S + K
Sbjct: 89 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 148
Query: 443 SSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502
+ T T ++ K+ G + T + K A +++ AK P +T
Sbjct: 149 TVETKETTTTN-KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 207
Query: 503 ATKQVQRRPPPAGPRSERGEPPKSGDRSGY-SSPGSPGTPGSRSRTPSLPTPP------- 554
+ P P P+ PK + S+P +P P + T S PT P
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT-TKSAPTTPKEPAPTT 266
Query: 555 TRE-----PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
T+E PK+ A T +P++ KS T P P
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303
Score = 35.4 bits (80), Expect = 0.20
Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 44/273 (16%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEE--------PGSETSDAKSTPTAEDVTAPLV-DEGAPG 86
+G LKE TP + +E P S TSD K PT TAP E AP
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPT 703
Query: 87 KQAAAQPHT-EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL 145
P T E P TT+E + TP+ E ES + EP P L
Sbjct: 704 TPKKPAPTTPETPPPTTSEVS----TPTTTKEPTTIHKSPDESTPELS----AEPTPKAL 755
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKG 205
+ PG P T+ P+ T PE T + + + P +
Sbjct: 756 ENSPKE--PGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT- 804
Query: 206 AGGKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDG--RPPQTAARE---AT 254
KE + E+ E + V ++ QD+ P K + + P T ++ T
Sbjct: 805 ---KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 861
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
I P E A P SK +T P P
Sbjct: 862 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 894
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 82.8 bits (203), Expect = 1e-15
Identities = 136/583 (23%), Positives = 206/583 (35%), Gaps = 67/583 (11%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQE-PESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
T +E P+ E A T+ P + K ++P P + P
Sbjct: 315 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370
Query: 160 PEGPREATRQPSGTGPED---TEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
P+ P T++P+ T P++ T + AP K P + P + +
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----------PAPTTPKEPAPTTTK 419
Query: 217 EVDEDRDVDESSPQDSPPS--KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
E ++P++ P+ K++P P T + A + P P+ P K
Sbjct: 420 EPSP------TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473
Query: 275 VSTEIPASEPDGPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFPGAPG 332
+P P+ + P E T + P KE A + + P P
Sbjct: 474 EPAPTTPKKP-APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP---KETAPTTPK 529
Query: 333 EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKK 392
+ L T E P E+ P +P P+ A K+ + +
Sbjct: 530 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPAPTTPKAA-APNTPKEP 587
Query: 393 AKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTS 447
A T+ + A T P +PK P G++ ++ +P +P +PK ++ T+
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTT 645
Query: 448 RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQV 507
+ +S + K TP+G AP K A T PAP TP +A +
Sbjct: 646 KEPTSTTCD--------KPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTPKGTAPTTL 693
Query: 508 QRRPPPAGPR----SERGEPPKSGDRSGYSSPGSPGTPGSRS-RTPSLPTPPTREPKKVA 562
+ P P P+ E G S S +P TP + TP P P T PKK A
Sbjct: 694 -KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--PKKPA 750
Query: 563 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 605
T P++P S + T KS ST L +P
Sbjct: 751 --PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 791
Score = 82.4 bits (202), Expect = 1e-15
Identities = 133/588 (22%), Positives = 200/588 (34%), Gaps = 66/588 (11%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 360
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
TT +E TP+ E A T+EP +EP P + AP
Sbjct: 361 TTPKEP----TPTTPKEPAP-TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTT 409
Query: 160 PEGPREAT-RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P+ P T ++PS T P++ AP K K A + S
Sbjct: 410 PKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI------PGFPAEGAIPLPVDFL 272
E P + P K +P P T +E P P E A P +
Sbjct: 465 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524
Query: 273 SKVSTEIPASEPD--GPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFP 328
++ + P+ P+ P E T E TP +E A + +AA P
Sbjct: 525 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAP 581
Query: 329 GAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK------------PVSRVPQLKA 376
P E T + P ++ P+G P P+ A
Sbjct: 582 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 641
Query: 377 RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAV 431
+K T + DK A T+ + +A T P +PK P P G++ ++ +P
Sbjct: 642 PTTTKEPTST-TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700
Query: 432 CPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT-RIPA 490
+P +PK ++ T++ +S + +T TP+ AP K A T P
Sbjct: 701 PKKP--APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 758
Query: 491 KTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSL 550
T TP ++ + P EP + PG P T + P +
Sbjct: 759 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 818
Query: 551 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 598
T + + + TP + ++ K +TA K +SKI +T
Sbjct: 819 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE---KTTESKITAT 863
Score = 62.0 bits (149), Expect = 2e-09
Identities = 55/235 (23%), Positives = 90/235 (38%), Gaps = 17/235 (7%)
Query: 353 EPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSP 412
E + K PA +P P+ A + K+ T + K A T+ + A T +P
Sbjct: 243 ETTTKGPALTTPKEPTPTTPKEPAS--TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 300
Query: 413 KHPTPGSSDPLIQPSSPAVCPEP-PSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATP 471
K P P ++ + +P EP P++ K + T+++ + KE TP
Sbjct: 301 KEPAPTTT----KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE---------PAPTTP 347
Query: 472 RGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSG 531
+ AP K A T TP PK P + + P P + + P +
Sbjct: 348 KKPAPTTPKEPAPTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406
Query: 532 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
++P P ++ +P+ P P K A T +P++ KS T P P
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 461
Score = 57.0 bits (136), Expect = 7e-08
Identities = 123/594 (20%), Positives = 194/594 (32%), Gaps = 112/594 (18%)
Query: 50 TPTEDGSEEPG--SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAG 107
TP E P + T+ K TPT + AP P K A P P TT EE
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT----PEKPAPTTPEELAP--TTPEEP- 563
Query: 108 IGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT 167
TP+ +E A P + K +EP AP P+ P T
Sbjct: 564 ---TPTTPEEPA------PTTPKAAAPNTPKEP---------------APTTPKEPAPTT 599
Query: 168 -RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDE 226
++P+ T P++T AP K L + P ++P KE
Sbjct: 600 PKEPAPTTPKET-----APTTPKGTAPTTLKEPAPTTP-----KKPAPKELAPTTTKEPT 649
Query: 227 SSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA----EGAIPLPVDFLSKVSTEIPAS 282
S+ D P A G P T A + P PA +G P + + + + PA
Sbjct: 650 STTCDKP---APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 706
Query: 283 EPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEG-PEARGPS 341
+ P+ KG + T + P KE A + P P PE P+
Sbjct: 707 KELAPTT--TKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 760
Query: 342 LGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSA 401
E + EP+ + P P+L A K+ + + + T T ++
Sbjct: 761 TSEVSTPTTTKEPTTIHKS------PDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 814
Query: 402 KTLKNRPCLSPKHPTPGSSDPLIQP--SSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKL 459
K P+ T + ++P P K ++ T +T S
Sbjct: 815 K---------PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 865
Query: 460 KGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSE 519
+ T+ TP + + P T + T ++ +P
Sbjct: 866 QVTSTTTQDTTPF---------KITTLKTTTLAPKVTTTKKTITTTEIMNKPE------- 909
Query: 520 RGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP--------PKSP 571
E K DR+ S++ TP P PT+ PKK + P PK+
Sbjct: 910 --ETAKPKDRA----------TNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTT 956
Query: 572 SSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 625
+ + T P P + ++ + +T P V++ K D + +
Sbjct: 957 PTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1010
Score = 52.8 bits (125), Expect = 1e-06
Identities = 53/217 (24%), Positives = 84/217 (38%), Gaps = 17/217 (7%)
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT--PGSSDPLIQPSSPAVCPEPPSSPKHV 442
G+G D+ K +T ++ T N+ SPK T P + P + P+S + K
Sbjct: 130 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 189
Query: 443 SSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502
+ T T ++ K+ G + T + K A +++ AK P +T
Sbjct: 190 TVETKETTTTN-KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 248
Query: 503 ATKQVQRRPPPAGPRSERGEPPKSGDRSGY-SSPGSPGTPGSRSRTPSLPTPP------- 554
+ P P P+ PK + S+P +P P + T S PT P
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT-TKSAPTTPKEPAPTT 307
Query: 555 TRE-----PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
T+E PK+ A T +P++ KS T P P
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344
Score = 35.4 bits (80), Expect = 0.20
Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 44/273 (16%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEE--------PGSETSDAKSTPTAEDVTAPLV-DEGAPG 86
+G LKE TP + +E P S TSD K PT TAP E AP
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPT 744
Query: 87 KQAAAQPHT-EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL 145
P T E P TT+E + TP+ E ES + EP P L
Sbjct: 745 TPKKPAPTTPETPPPTTSEVS----TPTTTKEPTTIHKSPDESTPELS----AEPTPKAL 796
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKG 205
+ PG P T+ P+ T PE T + + + P +
Sbjct: 797 ENSPKE--PGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT- 845
Query: 206 AGGKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDG--RPPQTAARE---AT 254
KE + E+ E + V ++ QD+ P K + + P T ++ T
Sbjct: 846 ---KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 902
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
I P E A P SK +T P P
Sbjct: 903 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 935
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 82.8 bits (203), Expect = 1e-15
Identities = 136/583 (23%), Positives = 206/583 (35%), Gaps = 67/583 (11%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQE-PESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
T +E P+ E A T+ P + K ++P P + P
Sbjct: 367 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422
Query: 160 PEGPREATRQPSGTGPED---TEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
P+ P T++P+ T P++ T + AP K P + P + +
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----------PAPTTPKEPAPTTTK 471
Query: 217 EVDEDRDVDESSPQDSPPS--KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
E ++P++ P+ K++P P T + A + P P+ P K
Sbjct: 472 EPSP------TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525
Query: 275 VSTEIPASEPDGPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFPGAPG 332
+P P+ + P E T + P KE A + + P P
Sbjct: 526 EPAPTTPKKP-APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP---KETAPTTPK 581
Query: 333 EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKK 392
+ L T E P E+ P +P P+ A K+ + +
Sbjct: 582 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPAPTTPKAA-APNTPKEP 639
Query: 393 AKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTS 447
A T+ + A T P +PK P G++ ++ +P +P +PK ++ T+
Sbjct: 640 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTT 697
Query: 448 RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQV 507
+ +S + K TP+G AP K A T PAP TP +A +
Sbjct: 698 KEPTSTTCD--------KPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTPKGTAPTTL 745
Query: 508 QRRPPPAGPR----SERGEPPKSGDRSGYSSPGSPGTPGSRS-RTPSLPTPPTREPKKVA 562
+ P P P+ E G S S +P TP + TP P P T PKK A
Sbjct: 746 -KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--PKKPA 802
Query: 563 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 605
T P++P S + T KS ST L +P
Sbjct: 803 --PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 843
Score = 82.4 bits (202), Expect = 1e-15
Identities = 133/588 (22%), Positives = 200/588 (34%), Gaps = 66/588 (11%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 412
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
TT +E TP+ E A T+EP +EP P + AP
Sbjct: 413 TTPKEP----TPTTPKEPAP-TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTT 461
Query: 160 PEGPREAT-RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P+ P T ++PS T P++ AP K K A + S
Sbjct: 462 PKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI------PGFPAEGAIPLPVDFL 272
E P + P K +P P T +E P P E A P +
Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576
Query: 273 SKVSTEIPASEPD--GPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFP 328
++ + P+ P+ P E T E TP +E A + +AA P
Sbjct: 577 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAP 633
Query: 329 GAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK------------PVSRVPQLKA 376
P E T + P ++ P+G P P+ A
Sbjct: 634 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 693
Query: 377 RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAV 431
+K T + DK A T+ + +A T P +PK P P G++ ++ +P
Sbjct: 694 PTTTKEPTST-TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 752
Query: 432 CPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT-RIPA 490
+P +PK ++ T++ +S + +T TP+ AP K A T P
Sbjct: 753 PKKP--APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 810
Query: 491 KTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSL 550
T TP ++ + P EP + PG P T + P +
Sbjct: 811 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 870
Query: 551 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 598
T + + + TP + ++ K +TA K +SKI +T
Sbjct: 871 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE---KTTESKITAT 915
Score = 62.0 bits (149), Expect = 2e-09
Identities = 55/235 (23%), Positives = 90/235 (38%), Gaps = 17/235 (7%)
Query: 353 EPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSP 412
E + K PA +P P+ A + K+ T + K A T+ + A T +P
Sbjct: 295 ETTTKGPALTTPKEPTPTTPKEPAS--TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 352
Query: 413 KHPTPGSSDPLIQPSSPAVCPEP-PSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATP 471
K P P ++ + +P EP P++ K + T+++ + KE TP
Sbjct: 353 KEPAPTTT----KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE---------PAPTTP 399
Query: 472 RGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSG 531
+ AP K A T TP PK P + + P P + + P +
Sbjct: 400 KKPAPTTPKEPAPTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458
Query: 532 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
++P P ++ +P+ P P K A T +P++ KS T P P
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513
Score = 57.0 bits (136), Expect = 7e-08
Identities = 123/594 (20%), Positives = 194/594 (32%), Gaps = 112/594 (18%)
Query: 50 TPTEDGSEEPG--SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAG 107
TP E P + T+ K TPT + AP P K A P P TT EE
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT----PEKPAPTTPEELAP--TTPEEP- 615
Query: 108 IGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT 167
TP+ +E A P + K +EP AP P+ P T
Sbjct: 616 ---TPTTPEEPA------PTTPKAAAPNTPKEP---------------APTTPKEPAPTT 651
Query: 168 -RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDE 226
++P+ T P++T AP K L + P ++P KE
Sbjct: 652 PKEPAPTTPKET-----APTTPKGTAPTTLKEPAPTTP-----KKPAPKELAPTTTKEPT 701
Query: 227 SSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA----EGAIPLPVDFLSKVSTEIPAS 282
S+ D P A G P T A + P PA +G P + + + + PA
Sbjct: 702 STTCDKP---APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 758
Query: 283 EPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEG-PEARGPS 341
+ P+ KG + T + P KE A + P P PE P+
Sbjct: 759 KELAPTT--TKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 812
Query: 342 LGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSA 401
E + EP+ + P P+L A K+ + + + T T ++
Sbjct: 813 TSEVSTPTTTKEPTTIHKS------PDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 866
Query: 402 KTLKNRPCLSPKHPTPGSSDPLIQP--SSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKL 459
K P+ T + ++P P K ++ T +T S
Sbjct: 867 K---------PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 917
Query: 460 KGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSE 519
+ T+ TP + + P T + T ++ +P
Sbjct: 918 QVTSTTTQDTTPF---------KITTLKTTTLAPKVTTTKKTITTTEIMNKPE------- 961
Query: 520 RGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP--------PKSP 571
E K DR+ S++ TP P PT+ PKK + P PK+
Sbjct: 962 --ETAKPKDRA----------TNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTT 1008
Query: 572 SSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 625
+ + T P P + ++ + +T P V++ K D + +
Sbjct: 1009 PTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1062
Score = 52.8 bits (125), Expect = 1e-06
Identities = 53/217 (24%), Positives = 84/217 (38%), Gaps = 17/217 (7%)
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT--PGSSDPLIQPSSPAVCPEPPSSPKHV 442
G+G D+ K +T ++ T N+ SPK T P + P + P+S + K
Sbjct: 182 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 241
Query: 443 SSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502
+ T T ++ K+ G + T + K A +++ AK P +T
Sbjct: 242 TVETKETTTTN-KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 300
Query: 503 ATKQVQRRPPPAGPRSERGEPPKSGDRSGY-SSPGSPGTPGSRSRTPSLPTPP------- 554
+ P P P+ PK + S+P +P P + T S PT P
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT-TKSAPTTPKEPAPTT 359
Query: 555 TRE-----PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
T+E PK+ A T +P++ KS T P P
Sbjct: 360 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Score = 35.4 bits (80), Expect = 0.20
Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 44/273 (16%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEE--------PGSETSDAKSTPTAEDVTAPLV-DEGAPG 86
+G LKE TP + +E P S TSD K PT TAP E AP
Sbjct: 738 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPT 796
Query: 87 KQAAAQPHT-EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL 145
P T E P TT+E + TP+ E ES + EP P L
Sbjct: 797 TPKKPAPTTPETPPPTTSEVS----TPTTTKEPTTIHKSPDESTPELS----AEPTPKAL 848
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKG 205
+ PG P T+ P+ T PE T + + + P +
Sbjct: 849 ENSPKE--PGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT- 897
Query: 206 AGGKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDG--RPPQTAARE---AT 254
KE + E+ E + V ++ QD+ P K + + P T ++ T
Sbjct: 898 ---KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 954
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
I P E A P SK +T P P
Sbjct: 955 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 987
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 82.8 bits (203), Expect = 1e-15
Identities = 136/583 (23%), Positives = 206/583 (35%), Gaps = 67/583 (11%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQE-PESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
T +E P+ E A T+ P + K ++P P + P
Sbjct: 408 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463
Query: 160 PEGPREATRQPSGTGPED---TEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
P+ P T++P+ T P++ T + AP K P + P + +
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----------PAPTTPKEPAPTTTK 512
Query: 217 EVDEDRDVDESSPQDSPPS--KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
E ++P++ P+ K++P P T + A + P P+ P K
Sbjct: 513 EPSP------TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566
Query: 275 VSTEIPASEPDGPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFPGAPG 332
+P P+ + P E T + P KE A + + P P
Sbjct: 567 EPAPTTPKKP-APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP---KETAPTTPK 622
Query: 333 EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKK 392
+ L T E P E+ P +P P+ A K+ + +
Sbjct: 623 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPAPTTPKAA-APNTPKEP 680
Query: 393 AKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTS 447
A T+ + A T P +PK P G++ ++ +P +P +PK ++ T+
Sbjct: 681 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTT 738
Query: 448 RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQV 507
+ +S + K TP+G AP K A T PAP TP +A +
Sbjct: 739 KEPTSTTCD--------KPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTPKGTAPTTL 786
Query: 508 QRRPPPAGPR----SERGEPPKSGDRSGYSSPGSPGTPGSRS-RTPSLPTPPTREPKKVA 562
+ P P P+ E G S S +P TP + TP P P T PKK A
Sbjct: 787 -KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT--PKKPA 843
Query: 563 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 605
T P++P S + T KS ST L +P
Sbjct: 844 --PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 884
Score = 82.4 bits (202), Expect = 1e-15
Identities = 133/588 (22%), Positives = 200/588 (34%), Gaps = 66/588 (11%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 453
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
TT +E TP+ E A T+EP +EP P + AP
Sbjct: 454 TTPKEP----TPTTPKEPAP-TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTT 502
Query: 160 PEGPREAT-RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P+ P T ++PS T P++ AP K K A + S
Sbjct: 503 PKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI------PGFPAEGAIPLPVDFL 272
E P + P K +P P T +E P P E A P +
Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617
Query: 273 SKVSTEIPASEPD--GPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFP 328
++ + P+ P+ P E T E TP +E A + +AA P
Sbjct: 618 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAP 674
Query: 329 GAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK------------PVSRVPQLKA 376
P E T + P ++ P+G P P+ A
Sbjct: 675 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 734
Query: 377 RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAV 431
+K T + DK A T+ + +A T P +PK P P G++ ++ +P
Sbjct: 735 PTTTKEPTST-TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 793
Query: 432 CPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT-RIPA 490
+P +PK ++ T++ +S + +T TP+ AP K A T P
Sbjct: 794 PKKP--APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 851
Query: 491 KTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSL 550
T TP ++ + P EP + PG P T + P +
Sbjct: 852 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 911
Query: 551 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 598
T + + + TP + ++ K +TA K +SKI +T
Sbjct: 912 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE---KTTESKITAT 956
Score = 62.0 bits (149), Expect = 2e-09
Identities = 55/235 (23%), Positives = 90/235 (38%), Gaps = 17/235 (7%)
Query: 353 EPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSP 412
E + K PA +P P+ A + K+ T + K A T+ + A T +P
Sbjct: 336 ETTTKGPALTTPKEPTPTTPKEPAS--TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 393
Query: 413 KHPTPGSSDPLIQPSSPAVCPEP-PSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATP 471
K P P ++ + +P EP P++ K + T+++ + KE TP
Sbjct: 394 KEPAPTTT----KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE---------PAPTTP 440
Query: 472 RGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSG 531
+ AP K A T TP PK P + + P P + + P +
Sbjct: 441 KKPAPTTPKEPAPTTP-KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499
Query: 532 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
++P P ++ +P+ P P K A T +P++ KS T P P
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 554
Score = 57.0 bits (136), Expect = 7e-08
Identities = 123/594 (20%), Positives = 194/594 (32%), Gaps = 112/594 (18%)
Query: 50 TPTEDGSEEPG--SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAG 107
TP E P + T+ K TPT + AP P K A P P TT EE
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT----PEKPAPTTPEELAP--TTPEEP- 656
Query: 108 IGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT 167
TP+ +E A P + K +EP AP P+ P T
Sbjct: 657 ---TPTTPEEPA------PTTPKAAAPNTPKEP---------------APTTPKEPAPTT 692
Query: 168 -RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDE 226
++P+ T P++T AP K L + P ++P KE
Sbjct: 693 PKEPAPTTPKET-----APTTPKGTAPTTLKEPAPTTP-----KKPAPKELAPTTTKEPT 742
Query: 227 SSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA----EGAIPLPVDFLSKVSTEIPAS 282
S+ D P A G P T A + P PA +G P + + + + PA
Sbjct: 743 STTCDKP---APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 799
Query: 283 EPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEG-PEARGPS 341
+ P+ KG + T + P KE A + P P PE P+
Sbjct: 800 KELAPTT--TKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 853
Query: 342 LGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSA 401
E + EP+ + P P+L A K+ + + + T T ++
Sbjct: 854 TSEVSTPTTTKEPTTIHKS------PDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 907
Query: 402 KTLKNRPCLSPKHPTPGSSDPLIQP--SSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKL 459
K P+ T + ++P P K ++ T +T S
Sbjct: 908 K---------PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 958
Query: 460 KGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSE 519
+ T+ TP + + P T + T ++ +P
Sbjct: 959 QVTSTTTQDTTPF---------KITTLKTTTLAPKVTTTKKTITTTEIMNKPE------- 1002
Query: 520 RGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP--------PKSP 571
E K DR+ S++ TP P PT+ PKK + P PK+
Sbjct: 1003 --ETAKPKDRA----------TNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTT 1049
Query: 572 SSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 625
+ + T P P + ++ + +T P V++ K D + +
Sbjct: 1050 PTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1103
Score = 52.8 bits (125), Expect = 1e-06
Identities = 53/217 (24%), Positives = 84/217 (38%), Gaps = 17/217 (7%)
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT--PGSSDPLIQPSSPAVCPEPPSSPKHV 442
G+G D+ K +T ++ T N+ SPK T P + P + P+S + K
Sbjct: 223 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 282
Query: 443 SSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502
+ T T ++ K+ G + T + K A +++ AK P +T
Sbjct: 283 TVETKETTTTN-KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 341
Query: 503 ATKQVQRRPPPAGPRSERGEPPKSGDRSGY-SSPGSPGTPGSRSRTPSLPTPP------- 554
+ P P P+ PK + S+P +P P + T S PT P
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT-TKSAPTTPKEPAPTT 400
Query: 555 TRE-----PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
T+E PK+ A T +P++ KS T P P
Sbjct: 401 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Score = 35.4 bits (80), Expect = 0.20
Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 44/273 (16%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEE--------PGSETSDAKSTPTAEDVTAPLV-DEGAPG 86
+G LKE TP + +E P S TSD K PT TAP E AP
Sbjct: 779 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPT 837
Query: 87 KQAAAQPHT-EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL 145
P T E P TT+E + TP+ E ES + EP P L
Sbjct: 838 TPKKPAPTTPETPPPTTSEVS----TPTTTKEPTTIHKSPDESTPELS----AEPTPKAL 889
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKG 205
+ PG P T+ P+ T PE T + + + P +
Sbjct: 890 ENSPKE--PGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT- 938
Query: 206 AGGKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDG--RPPQTAARE---AT 254
KE + E+ E + V ++ QD+ P K + + P T ++ T
Sbjct: 939 ---KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 995
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
I P E A P SK +T P P
Sbjct: 996 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 1028
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 80.9 bits (198), Expect = 4e-15
Identities = 136/535 (25%), Positives = 171/535 (31%), Gaps = 134/535 (25%)
Query: 56 SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAE--------EAG 107
S PGS S P E A G PG A P P G E E G
Sbjct: 188 SGHPGSPGSPGYQGPPGEPGQAG--PSGPPGPPGAIGPSG--PAGKDGESGRPGRPGERG 243
Query: 108 IGDTPSLEDEAA--GHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPG-----APLLP 160
+ P ++ A G + G + G E G PGL + +G+PG P+ P
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGE--NGLPGENGAPGPMGP 301
Query: 161 EG-PREATRQ--PSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEE 217
G P E R P G +G R + G GPP AG PG+K E
Sbjct: 302 RGAPGERGRPGLPGAAGARGNDGARGSD--------GQPGPPGPP-GTAGFPGSPGAKGE 352
Query: 218 VDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVST 277
V P SP S +P Q G P A PG P P +
Sbjct: 353 V---------GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMG---- 399
Query: 278 EIPASEPDGPSVGRAKGQDAPLEFTFHV-------EITPNVQKEQAHSEEHLGRAAFPGA 330
PA P P + A+G P E N K + G A PG
Sbjct: 400 --PAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGV 457
Query: 331 PGEGPEARGPSLGEDTKEADLPEPSEK--QPAAAPRGKPVSRVPQLKARMVSKSKDGTGS 388
PG + GED K+ EP AA RG P R P
Sbjct: 458 PG--------AKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGP---------------- 493
Query: 389 DDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSR 448
+ + PG P + +P P+ P+ + R
Sbjct: 494 ----------------------AGPNGIPGEKGPAGERGAPG-----PAGPRGAAGEPGR 526
Query: 449 TGSSGAKEMKLK-------GADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPS 501
G G M+ G+DGK PPG +G++ P P P+ P
Sbjct: 527 DGVPGGPGMRGMPGSPGGPGSDGKP--------GPPGSQGESGRPGPPG--PSGPRGQPG 576
Query: 502 SATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRT-PSLPTPPT 555
V P GP+ G P K+G+R G PG G PG T P P PT
Sbjct: 577 -----VMGFP---GPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623
Score = 72.8 bits (177), Expect = 1e-12
Identities = 155/654 (23%), Positives = 211/654 (32%), Gaps = 123/654 (18%)
Query: 13 DHAGTYGLGDRKDQG--GYTMHQDQEGDTDAGLKESPLQTPTEDGSEE-PGSETSDAKST 69
+ G G G + G G T Q G T G + P G + PG+ ++
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG 654
Query: 70 PTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEA--GIGDTPSLEDEAAGHVTQEPE 127
E P D GAPG P + G E G+ P L A PE
Sbjct: 655 KPGEP--GPKGDAGAPGA-----PGGKGDAGAPGERGPPGLAGAPGLRGGAG---PPGPE 704
Query: 128 SGKVVQEGFLREPGPPGLSHQL-MSGMPG--APLLPEGPREATRQPSGTGPEDTEG--GR 182
GK G PGPPG + + GMPG L GP+ +P G G + G G
Sbjct: 705 GGK----GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGP 760
Query: 183 HAPELLKHQLLGDLHQEGPPL----KGAGGKER-PGSKEEVDEDRDVDESSPQDSPPSKA 237
P G + GP KG GG PG + E+ P
Sbjct: 761 RGPT-------GPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPG 813
Query: 238 SPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDA 297
+P Q+G P R A PG EG P V+ S P GP
Sbjct: 814 APGQNGEPGGKGERGA---PGEKGEGGPP-------GVAGPPGGSGPAGPP--------- 854
Query: 298 PLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPG-EGPEARGPSLGEDTKEADLPEPSE 356
P K + S G A FPGA G GP + G P PS
Sbjct: 855 ----------GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP-------PGPSG 897
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTR--------------SSAK 402
P G P + VS K G +K + + A+
Sbjct: 898 SPGKDGPPG-PAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956
Query: 403 TLKNRPCLSPKHPTPGSSDPLIQPSSPAVC----PEPPSSPKHVSSVTSRTGSSGAKEMK 458
L P + +PG + P P P+ + + G G
Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016
Query: 459 LKGADGKT-KIATPRGAAPPGQKGQANATRIPAKT-PPAPKTP--------------PSS 502
G+DG + +P G G+ G A P PP P P P+
Sbjct: 1017 --GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAG 1074
Query: 503 ATKQVQRR--PPPAGPRSERGEPPK------SGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
A R P P GPR ++GE + G R +PG+PG+PG + ++ +P
Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG 1134
Query: 555 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKH--QPG 606
P+ PP ++ P+ P + + + GS + H QPG
Sbjct: 1135 PAGPRGPVGPSGPPGKDGTSG---HPGPIGPPGPRGNRGERGSEGSPGHPGQPG 1185
Score = 69.7 bits (169), Expect = 1e-11
Identities = 125/476 (26%), Positives = 154/476 (32%), Gaps = 103/476 (21%)
Query: 140 PGPPGLS-HQLMSGMPG-----------APLLPEGPREATRQPSGTGPEDTEGGRHAPEL 187
PGPPG S H G PG P P GP A PSG +D E GR
Sbjct: 182 PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG-PSGPAGKDGESGRPGRP- 239
Query: 188 LKHQLLGDLHQEGPP-LKG-AGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRP 245
G+ GPP +KG AG PG K D E +P K ++G P
Sbjct: 240 ------GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKG---ENGLP 290
Query: 246 PQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHV 305
+ A G P E P P A+G D
Sbjct: 291 GENGAPGPMGPRGAPGE------------------RGRPGLPGAAGARGNDGA------- 325
Query: 306 EITPNVQKEQAHSEEHLGRAAFPGAPGE----GPEARGPSLGEDTKEADLPEPSEKQPAA 361
Q G A FPG+PG GP S G + + P P A
Sbjct: 326 ----RGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE-PGPQGHAGAQ 380
Query: 362 APRGKP-VSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
P G P ++ P K M G + P + + PG
Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGIPGA------------PGLMGARGPPGPAGANGAPGLR 428
Query: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLK-------GADGKTKIATPRG 473
+P EP P+ G GAK K GA+G A RG
Sbjct: 429 GGAGEPGKNGAKGEP--GPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERG 486
Query: 474 AAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSG-- 531
A PG +G A IP + PA + + P PAGPR GEP + G G
Sbjct: 487 A--PGFRGPAGPNGIPGEKGPAGE----------RGAPGPAGPRGAAGEPGRDGVPGGPG 534
Query: 532 -YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
PGSPG PGS + P PP + + R P PS + + P P
Sbjct: 535 MRGMPGSPGGPGSDGK----PGPPGSQGES---GRPGPPGPSGPRGQPGVMGFPGP 583
Score = 69.7 bits (169), Expect = 1e-11
Identities = 131/511 (25%), Positives = 164/511 (32%), Gaps = 79/511 (15%)
Query: 83 GAPGKQAAAQPHTEIPEGTTAEEAGIGDT-PSLEDEAAGHVTQEPESGKVVQEGFLREPG 141
G PG AA T +G E G+G P + G + GK G G
Sbjct: 711 GPPGPPGAAG--TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768
Query: 142 PPGLSHQLMS-GMPGAPLLP--EGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQ 198
PPG + Q G GAP LP GPR + + TGP G AP Q
Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG-----------Q 817
Query: 199 EGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPG 258
G P GGK G+ E E + P P G + + G
Sbjct: 818 NGEP----GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAG 873
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEP--DGPSVGRAKGQDAPLEFTFHVEITPNVQKEQA 316
FP +P P P+ P DGP G A AP P Q
Sbjct: 874 FPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP-GPAGNTGAPGSPGVS---GPKGDAGQP 929
Query: 317 HSEEHLGRAAFPGAPGE--------------GPEARGP--SLGEDTKEADLPEPSEKQPA 360
+ G PGAPG P GP S G + + +P
Sbjct: 930 GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANG-L 988
Query: 361 AAPRGKPVSR-VPQLKARMVSKSKDGT-GSDDKKAKTSTRSSA--KTLKNRPCL--SPKH 414
+ RG P + +P L +DG GSD + + + P +P H
Sbjct: 989 SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048
Query: 415 P-TPGSSDPLIQ--------PSSPAVCPEP--------PSSPKHVSSVTSRTGSSGAKEM 457
P PG P + P+ PA P P P P+ T G++G K
Sbjct: 1049 PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH 1108
Query: 458 KLKGADGKTKIATPRGAAPPGQKGQANATRIPA----KTPPAPKTPPSSATKQVQRRP-P 512
+ G G P PG GQ A P + P P PP P
Sbjct: 1109 R--GFPGN-----PGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIG 1161
Query: 513 PAGPRSERGEPPKSGDRSGYSSPGSPGTPGS 543
P GPR RGE G PG PG PG+
Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192
Score = 43.5 bits (101), Expect = 7e-04
Identities = 56/220 (25%), Positives = 70/220 (31%), Gaps = 49/220 (22%)
Query: 345 DTKEADLPEPSEK---------QPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKT 395
D +E D P P QP AP P + PQ G D
Sbjct: 68 DDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQ-----------GPKGDPGPPGI 116
Query: 396 STRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVS-SVTSRTGSSGA 454
R+ + +P +PGS P P +C P+ P++ S S SG
Sbjct: 117 PGRNGDPGIPGQP------GSPGS------PGPPGICESCPTGPQNYSPQYDSYDVKSGV 164
Query: 455 KEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPA 514
L G G P G PPG G P +P +P + P+
Sbjct: 165 AVGGLAGYPGPAGPPGPPG--PPGTSGH----------PGSPGSPGYQGPPGEPGQAGPS 212
Query: 515 GPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
GP G SG G PG PG R LP PP
Sbjct: 213 GPPGPPGAIGPSGPAGKDGESGRPGRPGER----GLPGPP 248
Score = 34.3 bits (77), Expect = 0.45
Identities = 39/156 (25%), Positives = 56/156 (35%), Gaps = 33/156 (21%)
Query: 430 AVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIP 489
AVCP+PP++P + G G PPG G+ IP
Sbjct: 86 AVCPQPPTAPTRPPNGQGPQGPKG-------------------DPGPPGIPGRNGDPGIP 126
Query: 490 AKTPPAPKTP-PSSATKQVQRRPPPAGPRSERGEPPKS---GDRSGYSSP----GSPGTP 541
+ P +P +P P + P P+ + + G +GY P G PG P
Sbjct: 127 GQ-PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPP 185
Query: 542 GSRSRTPSLPTP----PTREPKKVAVVRTPPKSPSS 573
G+ S +P P EP + A PP P +
Sbjct: 186 GTSGHPGSPGSPGYQGPPGEPGQ-AGPSGPPGPPGA 220
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 77.8 bits (190), Expect = 4e-14
Identities = 122/492 (24%), Positives = 156/492 (31%), Gaps = 104/492 (21%)
Query: 78 PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFL 137
P D G PG+ A P T E G G+ G
Sbjct: 1270 PPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGA----------------DGRPGSPGRA 1313
Query: 138 REPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLH 197
PG PG G+ G+P LP GPR P GP +G AP Q++G
Sbjct: 1314 GNPGTPGAP-----GLKGSPGLP-GPRG---DPGERGPRGPKGEPGAPG----QVIGG-- 1358
Query: 198 QEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIP 257
EGP L G G PG + + P+ PP A G R P
Sbjct: 1359 -EGPGLPGRKGD--PGPSGPPGPRGPLGDPGPR-GPPGLPGTAMKGDKGDRGERG----P 1410
Query: 258 GFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAH 317
P EG I EP P + + G P+ P + E+
Sbjct: 1411 PGPGEGGIA--------------PGEPGLPGLPGSPGPQGPVG-------PPGKKGEKGD 1449
Query: 318 SEEHL-GRAAFPGAPGEG-----PEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRV 371
SE+ G PG+PGE P A GP G+ L E EK P +
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPK-GDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508
Query: 372 PQLKARMVSKSKDG----TGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPS 427
P + R +K +G TG +K + PG +P
Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGE----------------------PG------RPG 1540
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
PAV + PK G GA ++ G G + P P G G
Sbjct: 1541 DPAVVGPAVAGPKGEKGDVGPAGPRGATGVQ--GERGPPGLVLPGDPGPKGDPGDRGPIG 1598
Query: 488 IPAKT-PPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSR 546
+ + PP PP K RP P GP RG + G++ PG PG PG
Sbjct: 1599 LTGRAGPPGDSGPPGE--KGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656
Query: 547 TPSLPTPPTREP 558
P R P
Sbjct: 1657 RGLRGAPGVRGP 1668
Score = 77.0 bits (188), Expect = 6e-14
Identities = 138/542 (25%), Positives = 172/542 (31%), Gaps = 93/542 (17%)
Query: 41 AGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
AG+K S L+ E E GS P E P D G G P E P G
Sbjct: 1949 AGIKASALREIVETWDESSGS------FLPVPERRRGPKGDSGEQGP-----PGKEGPIG 1997
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLP 160
E GD + + E G G EPG PG+ PG P
Sbjct: 1998 FPGERGLKGDRGDPGPQGPPGLALG-ERGPPGPSGLAGEPGKPGI--------PGLPGRA 2048
Query: 161 EGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPP-LKGAGGKERP-GSKEEV 218
G EA R P G +G R G+ ++GPP L G G P G K V
Sbjct: 2049 GGVGEAGR-PGERGERGEKGER-----------GEQGRDGPPGLPGTPGPPGPPGPKVSV 2096
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLP--VDFLSKVS 276
DE S Q P K + + G + +PG + P P D +
Sbjct: 2097 DEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLP 2155
Query: 277 TEIPASEPDG-PSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-G 334
E + P+G P + +G P+ H + P A G + G PGE G
Sbjct: 2156 GERGMAGPEGKPGLQGPRGPPGPVGG--HGDPGPPGAPGLAGPAGPQGPSGLKGEPGETG 2213
Query: 335 PEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT-GSDDKKA 393
P RG L T LP P P+G P L ++ K G G D
Sbjct: 2214 PPGRG--LTGPTGAVGLPGPPGPSGLVGPQGSP-----GLPGQVGETGKPGAPGRDGASG 2266
Query: 394 KTSTRSSAKTLKNRPCLSPKHP-TPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
K R S P P +PG P+ P P + + G+
Sbjct: 2267 KDGDRGS-----------PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAP 2315
Query: 453 GAKEMKL---KGADGKTKIATPRGA-------------------APPGQKGQANATRIPA 490
G L GA G + PRG PG KG +
Sbjct: 2316 GGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGV 2375
Query: 491 KTPPAPKTPPS----------SATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
P P PP V P GPR E G+P SG+R PG G
Sbjct: 2376 PGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435
Query: 541 PG 542
PG
Sbjct: 2436 PG 2437
Score = 73.2 bits (178), Expect = 9e-13
Identities = 142/578 (24%), Positives = 193/578 (33%), Gaps = 80/578 (13%)
Query: 44 KESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA-AAQPHTEIPEGTT 102
KE P+ P E G + G P L + G PG A +P G
Sbjct: 1992 KEGPIGFPGERGLK--GDRGDPGPQGPPG----LALGERGPPGPSGLAGEPGKPGIPGLP 2045
Query: 103 AEEAGIGDT--PSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLL- 159
G+G+ P E G + E G+ G PGPPG +S P L
Sbjct: 2046 GRAGGVGEAGRPGERGER-GEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLS 2104
Query: 160 ----PEGPREATRQPSGTGPEDTEGGRHAPELLKHQ-LLGDLHQEGPP-LKGAGGKERPG 213
P G + A +P G + +G R P + + G Q+G P L G G P
Sbjct: 2105 GEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPE 2164
Query: 214 SKEEVDEDRD-------------------VDESSPQDSPPSKASPAQDGRPPQ--TAARE 252
K + R + PQ K P + G P + T
Sbjct: 2165 GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG 2224
Query: 253 ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312
A +PG P + P +P P A G+D + V +P +
Sbjct: 2225 AVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGD-RGSPGVPGSPGLP 2283
Query: 313 KEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAA-APRGKPVSRV 371
G GAPG+ + GE L +P A RG P R
Sbjct: 2284 GPVGPK----GEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRG 2339
Query: 372 PQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAV 431
+ +A + D G D +K K K P + PGS P P P V
Sbjct: 2340 EKGEAGRAGEPGD-PGEDGQKGAPGP----KGFKGDPGVG----VPGSPGP---PGPPGV 2387
Query: 432 -----CPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT 486
P P +P V +TG G EM G G+ +A PPG++G
Sbjct: 2388 KGDLGLPGLPGAPG-VVGFPGQTGPRG--EMGQPGPSGERGLA-----GPPGREGIPGPL 2439
Query: 487 RIPAKTPPAPKTPPSSATKQVQRRPPPAG---PRSERGEPPKSGD--RSGYSSP----GS 537
P PP PP ++ + + P G PR ERGEP G+ R G P G
Sbjct: 2440 GPPG--PPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGP 2497
Query: 538 PGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 575
PG+ G R + + + K + V P P AK
Sbjct: 2498 PGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAK 2535
Score = 61.6 bits (148), Expect = 3e-09
Identities = 130/565 (23%), Positives = 186/565 (32%), Gaps = 83/565 (14%)
Query: 21 GDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGS----EEPGSETSDAKSTPTAEDVT 76
G+R ++G +Q D GL +P P G +EPG S + P +
Sbjct: 2058 GERGERGEKGERGEQGRDGPPGLPGTP-GPPGPPGPKVSVDEPGPGLSGEQGPPGLKGA- 2115
Query: 77 APLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDT-PSLEDEAAGHVTQEPESGKVVQEG 135
+G PG P + G + G+ P +D G + +G + G
Sbjct: 2116 -----KGEPGSNGDQGPKGD--RGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPG 2168
Query: 136 FLREPGPPG-LSHQLMSGMPGAPLL-----PEGPREATRQPSGTGPEDTEGGRHAPELLK 189
GPPG + G PGAP L P+GP +P TGP G P
Sbjct: 2169 LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGR--GLTGPT--- 2223
Query: 190 HQLLGDLHQEGPPLKGA--GGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQ 247
G + GPP G + PG +V E +P +DG +
Sbjct: 2224 ----GAVGLPGPPGPSGLVGPQGSPGLPGQVGETG------------KPGAPGRDGASGK 2267
Query: 248 TAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGR--AKGQD-APLEFTFH 304
R + +PG P +P PV + P P VG AKG+ AP
Sbjct: 2268 DGDRGSPGVPGSPG---LPGPVGPKGEPG---PTGAPGQAVVGLPGAKGEKGAPGGLAGD 2321
Query: 305 VEITPNVQKEQA-----HSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQP 359
+ P + ++ + GRA PG PGE + P + + P P
Sbjct: 2322 LVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGP 2381
Query: 360 AAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGS 419
P K +P L G + S + L P + PG
Sbjct: 2382 PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP---GREGIPG- 2437
Query: 420 SDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK----EMKLKGADGKTKIATPRGAA 475
PL P P P +S G G + E ++G DG+ PRG
Sbjct: 2438 --PLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLT 2495
Query: 476 PP-------GQKGQANATRIPAKT--------PPAPKTPPSSATKQVQRR-PPPAGPRSE 519
P G+KG + + PP P+ ++ R GPR +
Sbjct: 2496 GPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGD 2555
Query: 520 RGEPPKSGDRSGYSSPGSPGTPGSR 544
G+P G + GS G PG R
Sbjct: 2556 NGDPGDKGSKGEPGDKGSAGLPGLR 2580
Score = 58.5 bits (140), Expect = 2e-08
Identities = 130/546 (23%), Positives = 172/546 (31%), Gaps = 87/546 (15%)
Query: 81 DEGAPGKQAA-AQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLRE 139
++G PG +P +G E+ G A+G ++ G+ G L
Sbjct: 1834 EDGKPGLNGKNGEPGDPGEDGRKGEKGDSG--------ASGREGRDGPKGERGAPGILGP 1885
Query: 140 PGPPGLSHQL---MSGMPGAP--LLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLG 194
GPPGL + G PG P P+G R T G G R P G
Sbjct: 1886 QGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEP--------G 1937
Query: 195 DLHQEGPPLKGAGGK------------ERPGSKEEVDEDRDVDE-SSPQDSPPSKASPAQ 241
+ L+ AG K E GS V E R + S + PP K P
Sbjct: 1938 SVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPI- 1996
Query: 242 DGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSV----GRAKGQDA 297
G P + + PG +G L + A EP P + GRA G
Sbjct: 1997 -GFPGERGLKGDRGDPG--PQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVG- 2052
Query: 298 PLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEK 357
E E +K + + G PG PG P GP + D L
Sbjct: 2053 --EAGRPGERGERGEKGERGEQGRDGPPGLPGTPGP-PGPPGPKVSVDEPGPGLSGEQGP 2109
Query: 358 QPAAAPRGKPVSR----------VPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNR 407
+G+P S VP +K + + G D + +
Sbjct: 2110 PGLKGAKGEPGSNGDQGPKGDRGVPGIKG---DRGEPGPRGQDGNPGLPGERGMAGPEGK 2166
Query: 408 PCL----SPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGAD 463
P L P P G DP P +P + P+ P+ S + G +G L G
Sbjct: 2167 PGLQGPRGPPGPVGGHGDP-GPPGAPGLA--GPAGPQGPSGLKGEPGETGPPGRGLTGPT 2223
Query: 464 GKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEP 523
G + P G P G G + +P QV P P + G
Sbjct: 2224 GAVGLPGPPG--PSGLVGPQGSPGLPG---------------QVGETGKPGAPGRD-GAS 2265
Query: 524 PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPV 583
K GDR PGSPG PG P PT P + V K A L V
Sbjct: 2266 GKDGDRGSPGVPGSPGLPGPVG--PKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLV 2323
Query: 584 PMPDLK 589
P K
Sbjct: 2324 GEPGAK 2329
Score = 56.2 bits (134), Expect = 1e-07
Identities = 124/533 (23%), Positives = 176/533 (33%), Gaps = 64/533 (12%)
Query: 67 KSTPTAEDVTAPLVDEGAPGKQAAAQ-PHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQE 125
+ P P + GAPG+ + P +G G L D
Sbjct: 1334 RGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGL 1393
Query: 126 PESGKVVQEGFLREPGPPGLSHQ-LMSGMPGAPLLP--EGPREATRQPSGTGPE-DTEGG 181
P + +G E GPPG + G PG P LP GP+ P G + D+E G
Sbjct: 1394 PGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDG 1453
Query: 182 RHAPELLKHQLLGDLHQEGP--PLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASP 239
AP L G ++GP P G K G + E + E P S+ P
Sbjct: 1454 --APGLPGQP--GSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509
Query: 240 AQDGRP--------PQTAAREATS-IPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP-SV 289
GRP P R+ PG P + A+ P ++ E P GP
Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPA--VAGPKGEKGDVGPAGPRGA 1567
Query: 290 GRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPG---APGE--GPEARGPS--L 342
+G+ P + P GRA PG PGE P GP +
Sbjct: 1568 TGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV 1627
Query: 343 GEDTKEADLPEPSEKQPAAAPR--GKPVSR----VPQLKARMVSKSKDGTGSDDKKAKTS 396
G ++ ++ E ++ P P GK R P ++ + K G +D + +
Sbjct: 1628 GPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSP 1687
Query: 397 TRSSAKTLKNRPCLSPKHPT-------PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRT 449
S K + P P P PG+ + +P E P PK +
Sbjct: 1688 GSSGPKGDRGEP--GPPGPPGRLVDTGPGAREKG-EPGDRG--QEGPRGPKGDPGLPGAP 1742
Query: 450 GSSGAKEMK-LKGADGKTKIATPRGA----APPGQKGQANATRIPAKTPPA--------- 495
G G + + G G + P G PPG G++ P P+
Sbjct: 1743 GERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKA 1802
Query: 496 --PKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSR 546
P + Q P P+GP G+P + G G PG PG R
Sbjct: 1803 GDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGR 1855
Score = 55.8 bits (133), Expect = 1e-07
Identities = 136/551 (24%), Positives = 178/551 (32%), Gaps = 100/551 (18%)
Query: 35 QEGDTDAGLKESPLQ--TPTEDGSEEP----GSETSDAKSTPTAE-------DVTAPLVD 81
++GD++ G P Q +P E G P G + P E P
Sbjct: 1446 EKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGS 1505
Query: 82 EGAPGKQAAAQPHTEIPEGTTA---------EEAGIGDTPSLEDEAAGHVTQEPESGKVV 132
G PG A +P + PEG E GD + AG ++ + G
Sbjct: 1506 RGLPG--VAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAG 1563
Query: 133 QEGFLR---EPGPPGLSHQLMSGMPGAPLLP--EGPREATRQ---PSGTGPEDTEG--GR 182
G E GPPGL ++ G PG P GP T + P +GP +G GR
Sbjct: 1564 PRGATGVQGERGPPGL---VLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR 1620
Query: 183 HAPE-----LLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKA 237
P + +G+ EGPP G PG E P +
Sbjct: 1621 PGPPGPVGPRGRDGEVGEKGDEGPP----GDPGLPGKAGERGLRGAPGVRGPVGEKGDQG 1676
Query: 238 SPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDA 297
P +DGR + ++ G E P P L V T A E P +GQ+
Sbjct: 1677 DPGEDGR---NGSPGSSGPKGDRGEPGPPGPPGRL--VDTGPGAREKGEPG---DRGQEG 1728
Query: 298 PLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEA-RGPSLGEDTKEADLPEPS 355
P G PGAPGE G E RGP P P
Sbjct: 1729 P--------------------RGPKGDPGLPGAPGERGIEGFRGP-----------PGPQ 1757
Query: 356 EKQPAAAPRGKPVSRVPQ-LKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKH 414
P G+ R P L R K G + ++ P L +
Sbjct: 1758 GDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQ 1817
Query: 415 PTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK-EMKLKGADGKTKIATPRG 473
PG S P P P +P + K+ G G K E GA G+ P+G
Sbjct: 1818 GLPGPSGPPGLPGKPGEDGKPGLNGKN--GEPGDPGEDGRKGEKGDSGASGREGRDGPKG 1875
Query: 474 A-APPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGY 532
PG G +P P PP V P GP+ +RGE G++
Sbjct: 1876 ERGAPGILGPQGPPGLPG-----PVGPPGQGFPGV---PGGTGPKGDRGETGSKGEQGLP 1927
Query: 533 SSPGSPGTPGS 543
G G PGS
Sbjct: 1928 GERGLRGEPGS 1938
Score = 52.4 bits (124), Expect = 2e-06
Identities = 125/527 (23%), Positives = 169/527 (32%), Gaps = 103/527 (19%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGK--VVQEGFLR 138
+ GA G + P E E A E G P ED G + G V G
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPG---DPG-EDGQKGAPGPKGFKGDPGVGVPGSPG 2380
Query: 139 EPGPPGLSHQL-MSGMPGAPLL-----PEGPREATRQPSGTGPEDTEG--GRHAPELLKH 190
PGPPG+ L + G+PGAP + GPR QP +G G GR
Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREG------ 2434
Query: 191 QLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAA 250
+ G L GPP G+ G + D V P+ +DGRP Q
Sbjct: 2435 -IPGPLGPPGPP--GSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGP 2491
Query: 251 REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPN 310
R T PG E + VG A
Sbjct: 2492 RGLTGPPGSRGERG--------------------EKGDVGSA-----------------G 2514
Query: 311 VQKEQAHSEEHLGRAAFPGAPGEGPEARGPSL--GEDTKEADLPEPSEKQPAAAPRGKPV 368
++ ++ S LG GA G+ E RGP G+ D +P +K P K
Sbjct: 2515 LKGDKGDSAVILGPPGPRGAKGDMGE-RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGS 2573
Query: 369 SRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSS 428
+ +P L+ + + + G A + P K PG I+
Sbjct: 2574 AGLPGLRGLLGPQGQPG---------------AAGIPGDPGSPGKDGVPG-----IRGEK 2613
Query: 429 PAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLK-GADGKTKIATPRGA-APPGQKGQANAT 486
V P K V G G K K + G G+ +A +G PG GQ+ A
Sbjct: 2614 GDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAP 2673
Query: 487 RIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGE---------PPKSGDRSGYSSPGS 537
P + +P P G + E+GE P SG+ PG
Sbjct: 2674 GKEGLIGP-------KGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGP 2726
Query: 538 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP--PKSPSSAKSRLQTAP 582
PG+ G R R P VV P P +P + + P
Sbjct: 2727 PGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGP 2773
Score = 47.4 bits (111), Expect = 5e-05
Identities = 83/345 (24%), Positives = 109/345 (31%), Gaps = 75/345 (21%)
Query: 227 SSPQDSP-PSKASPAQDGRPPQTAAREATSIPGFP-------AEGAIPLPVDFLSKVSTE 278
+ P+ P P Q G P + R PG P A G P +K
Sbjct: 1240 TQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERG 1299
Query: 279 IPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEH--LGRAAFPGAPGEGPE 336
P ++ S GRA P ++ +P + + E G PGAPG+
Sbjct: 1300 FPGADGRPGSPGRAGNPGTP--GAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIG 1357
Query: 337 ARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTS 396
GP L ++ D P PS P G P R P GT K
Sbjct: 1358 GEGPGL--PGRKGD-PGPSGPPGPRGPLGDPGPRGPP--------GLPGTAMKGDKGDRG 1406
Query: 397 TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKE 456
R PG + I P P + P P SP
Sbjct: 1407 ERGP----------------PGPGEGGIAPGEPGL-PGLPGSPG---------------- 1433
Query: 457 MKLKGADGKTKIATPRG-AAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPA- 514
P+G PPG+KG+ + A P P S +Q R PP A
Sbjct: 1434 --------------PQGPVGPPGKKGEKGDSEDGAPGLPGQ---PGSPGEQGPRGPPGAI 1476
Query: 515 GPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK 559
GP+ +RG P G+ G PG GSR P + P+
Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPE 1521
Score = 42.4 bits (98), Expect = 0.002
Identities = 116/531 (21%), Positives = 170/531 (32%), Gaps = 123/531 (23%)
Query: 83 GAPGKQAAAQPHTEIPEGTTAEEAG--IGDTPSLEDEAA-------GHVTQEPESGKVVQ 133
GAPG+ P + +G AG +G+ + D G + E G +
Sbjct: 2296 GAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGE 2355
Query: 134 EGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLL 193
+G PGP G G+PG+P P GP P G G AP ++
Sbjct: 2356 DGQKGAPGPKGFKGDPGVGVPGSPG-PPGP------PGVKGDLGLPGLPGAPGVV----- 2403
Query: 194 GDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREA 253
G Q GP +G G+ P +R + ++ P P G P A
Sbjct: 2404 GFPGQTGP--RGEMGQPGPSG------ERGLAGPPGREGIPGPLGPP--GPPGSVGPPGA 2453
Query: 254 TSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSV----GRAKGQDAPLEFTFHVEITP 309
+ + G + + LP P E P + GR GQ+ P T P
Sbjct: 2454 SGLKGDKGDPGVGLPG----------PRGERGEPGIRGEDGRP-GQEGPRGLT-----GP 2497
Query: 310 NVQKEQAHSEEHLGRAAFPGAPGE--------GPEA-------RGPSL--GEDTKEADLP 352
+ + + +G A G G+ GP RGP G+ D
Sbjct: 2498 PGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNG 2557
Query: 353 EPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT-------GSDDKKAKTSTRSSA---- 401
+P +K P K + +P L+ + + + G GS K R
Sbjct: 2558 DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617
Query: 402 ----------KTLKNRPCLSPKHPTPGSSDP------------LIQPSSPAVCPEPPSS- 438
+ +K L + G + P + +P P P
Sbjct: 2618 FMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEG 2677
Query: 439 ---PKHVSSVTSRTGSSGAK-EMKLKGADGKTKIATPRG----AAPPGQKGQANAT---- 486
PK + G G + E +G G P G A PPG G
Sbjct: 2678 LIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEG 2737
Query: 487 ---RIPAKTPP------APKTPPSSATKQVQRRPPPAGPRSERGEPPKSGD 528
+ + PP AP P + + Q RP PAGPR E+GE + D
Sbjct: 2738 LQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/143 (29%), Positives = 55/143 (38%), Gaps = 38/143 (26%)
Query: 419 SSDPLIQPSSPAVCP-----EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRG 473
S D + + A+C +P P V + G G EM L+G G
Sbjct: 1221 SLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPG--EMGLRGQVG--------- 1269
Query: 474 AAPPGQKGQANATRIPAKT-PPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGY 532
PPG G +P +T P P+ PP SAT + ERG P G
Sbjct: 1270 --PPGDPG------LPGRTGAPGPQGPPGSATA-----------KGERGFPGADGRPGSP 1310
Query: 533 SSPGSPGTPGS--RSRTPSLPTP 553
G+PGTPG+ +P LP P
Sbjct: 1311 GRAGNPGTPGAPGLKGSPGLPGP 1333
Score = 39.7 bits (91), Expect = 0.011
Identities = 40/140 (28%), Positives = 49/140 (35%), Gaps = 12/140 (8%)
Query: 435 PPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPP 494
PP P + RTG+ G + A K + P PG G+A TP
Sbjct: 1270 PPGDP----GLPGRTGAPGPQGPP-GSATAKGERGFPGADGRPGSPGRAGNPG----TPG 1320
Query: 495 APKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
AP S + P GPR +GEP G G PG PG + P
Sbjct: 1321 APGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPG---LPGRKGDPGPSGPPG 1377
Query: 555 TREPKKVAVVRTPPKSPSSA 574
R P R PP P +A
Sbjct: 1378 PRGPLGDPGPRGPPGLPGTA 1397
Score = 36.6 bits (83), Expect = 0.091
Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 4/55 (7%)
Query: 503 ATKQVQRRPPPAG---PRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
A+ Q RP P P+ ++GEP + G R PG PG PG R+ P PP
Sbjct: 1236 ASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPG-RTGAPGPQGPP 1289
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 77.4 bits (189), Expect = 5e-14
Identities = 127/520 (24%), Positives = 170/520 (32%), Gaps = 106/520 (20%)
Query: 70 PTAEDVTAPLVDEGAPGKQA----AAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQE 125
P + P ++GAPG++ A + + P G +G P ED G + +
Sbjct: 1107 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVG--PPGEDGDKGEIGEP 1164
Query: 126 PESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAP 185
+ G +G E GPPG P GP+ QP +G + G R
Sbjct: 1165 GQKGSKGDKG---EQGPPG---------------PTGPQGPIGQPGPSGADGEPGPRG-- 1204
Query: 186 ELLKHQLLGDLHQEGP-----PLKGAGGKERPGSKEEVDEDRDVDESSPQDSP----PSK 236
+ L G EGP P G + PG E E DV + P P PS
Sbjct: 1205 ---QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSG 1261
Query: 237 ASPAQDGRPPQTAAREATSI-----------PGFPAEGAIPLPVDFLSKVSTEIPASEPD 285
A A + P ++ PG P EG P P + P+
Sbjct: 1262 APGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAG 1321
Query: 286 GPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGED 345
P G D P + G FPG PG P GP+ G+D
Sbjct: 1322 PPGPKGPPGDDGP--------------------KGSPGPVGFPGDPGP-PGEPGPA-GQD 1359
Query: 346 TKEADLPEPSE--KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSA-- 401
D + E + + P G+P P K + +K AK
Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPP 1419
Query: 402 -KTLKNRPCLSPKHPTP----GSSDPLIQ---PSSPAVCPEPPSSPKHVSSVTSRTGSSG 453
KT P +P P P G P+ + P SP P+ P P + G SG
Sbjct: 1420 GKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG--PDGPPGPMGPPGLPGLKGDSG 1477
Query: 454 AKEMK-------LKGADGKTKIATPRGAAPP----GQKGQANATRIPAKTPPAPKTPPSS 502
K K L G G+ RG P G KG+ T P P PP
Sbjct: 1478 PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG--PSGPIGPPGPPGL 1535
Query: 503 ATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPG 542
P P GP+ +G +G + PG PG PG
Sbjct: 1536 --------PGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPG 1567
Score = 71.2 bits (173), Expect = 3e-12
Identities = 121/500 (24%), Positives = 166/500 (33%), Gaps = 116/500 (23%)
Query: 83 GAPGKQAAAQPHTEI-PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPG 141
G G++ P E P G T + G++ D AG + +G GF G
Sbjct: 907 GPRGQRGPTGPRGERGPRGITGKPGPKGNSGG--DGPAGPPGERGPNGPQGPTGFPGPKG 964
Query: 142 PPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG--GRHAPELLKHQLLGDLHQE 199
PPG + G+PG P G R T TGP G G P + +G+
Sbjct: 965 PPGPPGK--DGLPGHP----GQRGETGFQGKTGPPGPPGVVGPQGPTG-ETGPMGERGHP 1017
Query: 200 GPP-------LKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAARE 252
GPP L G GKE G+K + P P +DG P
Sbjct: 1018 GPPGPPGEQGLPGLAGKE--GTKGD---------------PGPAGLPGKDGPP------- 1053
Query: 253 ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312
+ GFP + +P PV L E P P GP+ + A + P Q
Sbjct: 1054 --GLRGFPGDRGLPGPVGALGLKGNEGPPGPP-GPAGSPGERGPAGAAGPIGIPGRPGPQ 1110
Query: 313 KEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRV 371
G A GAPGE GP+ GP+ G D + + P P P
Sbjct: 1111 GPP-------GPAGEKGAPGEKGPQ--GPA-GRDGLQGPVGLPGPAGPVGPP-------- 1152
Query: 372 PQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAV 431
G D K + + ++ P PT G P+ QP
Sbjct: 1153 ---------------GEDGDKGEIGEPGQKGSKGDKGEQGPPGPT-GPQGPIGQPGPSGA 1196
Query: 432 CPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQA-NATRIPA 490
EP P+ + + G G + G G + G PPG+KG+ + ++
Sbjct: 1197 DGEP--GPRGQQGLFGQKGDEGPRGFP--GPPGPVGLQGLPG--PPGEKGETGDVGQMGP 1250
Query: 491 KTPPAPKTPPSSATKQVQRRPP----------------------------PAGPRSERGE 522
PP P+ P + + PP P GP+ ERGE
Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGE 1310
Query: 523 PPKSGDRSGYSSPGSPGTPG 542
+SG PG G PG
Sbjct: 1311 KGESGPSGAAGPPGPKGPPG 1330
Score = 55.8 bits (133), Expect = 1e-07
Identities = 117/472 (24%), Positives = 148/472 (31%), Gaps = 89/472 (18%)
Query: 100 GTTAEEAGIGDT-PSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPL 158
G E+ GD PS G + + G+V G EPGP GL P P
Sbjct: 637 GLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG------PKGPP 690
Query: 159 LPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P GP T GP+ G + P G Q+G P G + PG + +
Sbjct: 691 GPPGPPGVTGMDGQPGPKGNVGPQGEP--------GPPGQQGNP----GAQGLPGPQGAI 738
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTE 278
E P P P DG PP +E G P E P +
Sbjct: 739 GPP---GEKGPLGKPGLPGMPGADG-PPGHPGKE-----GPPGEKGGQGPPGPQGPIGYP 789
Query: 279 IPASEPDGPSVGRAKGQDAPL-EFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPG----E 333
P + KG E F P + + + G PG G E
Sbjct: 790 GPRGVKGADGIRGLKGTKGEKGEDGF-----PGFKGDMGIKGDR-GEIGPPGPRGEDGPE 843
Query: 334 GPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDG----TGSD 389
GP+ RG G + L P EK P +P R K G G++
Sbjct: 844 GPKGRG---GPNGDPGPLGPPGEKGKLGVP------GLPGYPGRQGPKGSIGFPGFPGAN 894
Query: 390 DKKAKTSTRSSAKTLKNRPCLSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSV 445
+K T P P P G + P + + +P PK S
Sbjct: 895 GEKGGRGT--------------PGKPGPRGQRGPTGPRGERGPRGITGKP--GPKGNSGG 938
Query: 446 TSRTGSSGAKEMKLKGADGKTKIATPRGA-------APPGQKGQANATRIPAKT-PPAP- 496
G G E G G T P+G PG GQ T KT PP P
Sbjct: 939 DGPAGPPG--ERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPP 996
Query: 497 ----KTPPSSATKQVQRR--PPPAGPRSERGEPPKSGDRSGYSSPGSPGTPG 542
P+ T + R P P GP E+G P +G PG G PG
Sbjct: 997 GVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPG 1048
Score = 55.1 bits (131), Expect = 2e-07
Identities = 126/499 (25%), Positives = 167/499 (33%), Gaps = 95/499 (19%)
Query: 124 QEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRH 183
Q G V +G EPGPPG G PGA LP GP+ A P GP
Sbjct: 704 QPGPKGNVGPQG---EPGPPG-----QQGNPGAQGLP-GPQGAIGPPGEKGP-------- 746
Query: 184 APELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDG 243
L K L G +GPP G GKE P E P P + DG
Sbjct: 747 ---LGKPGLPGMPGADGPP--GHPGKEGPPG--EKGGQGPPGPQGPIGYPGPRGVKGADG 799
Query: 244 RPPQTAAREATSIPGFPA-EGAIPLPVDFLSKVSTEIPASE--PDGPSV-GRAKGQDAPL 299
+ GFP +G + + D ++ P E P+GP G G PL
Sbjct: 800 IRGLKGTKGEKGEDGFPGFKGDMGIKGD-RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL 858
Query: 300 -----EFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE----------GPEA-RGPS-- 341
+ V P Q + +G FPGA GE GP RGP+
Sbjct: 859 GPPGEKGKLGVPGLPGYPGRQG-PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGP 917
Query: 342 LGEDTKEADLPEPSEKQPAAA--PRGKPVSRVPQ----------LKARMVSKSKDGT-GS 388
GE +P K + P G P R P K KDG G
Sbjct: 918 RGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGH 977
Query: 389 DDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSR 448
++ +T + + P+ PT G + P+ + P P P + + + +
Sbjct: 978 PGQRGETGFQGKTGPPGPPGVVGPQGPT-GETGPMGERGHPG--PPGPPGEQGLPGLAGK 1034
Query: 449 TGSSGAK-EMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQV 507
G+ G L G DG PPG +G +P + K
Sbjct: 1035 EGTKGDPGPAGLPGKDG-----------PPGLRGFPGDRGLPGPVG-------ALGLKGN 1076
Query: 508 QRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP 567
+ P P GP GE +G PG PG G PP +K A
Sbjct: 1077 EGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQG----------PPGPAGEKGAPGEKG 1126
Query: 568 PKSPSSAKSRLQTAPVPMP 586
P+ P + + LQ PV +P
Sbjct: 1127 PQGP-AGRDGLQ-GPVGLP 1143
Score = 53.9 bits (128), Expect = 6e-07
Identities = 121/534 (22%), Positives = 175/534 (32%), Gaps = 118/534 (22%)
Query: 29 YTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQ 88
Y D EG+T + P + E+ G E + +K A T + +E P
Sbjct: 262 YYTEGDGEGETYY------YEYPYYEDPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPT 315
Query: 89 AAAQPHTEIPEGTTAEE-AGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSH 147
AA P E EG EE GIGD + E + T P EG E P
Sbjct: 316 EAA-PMPETSEGAGKEEDVGIGDYDYVPSE--DYYTPSPYDDLTYGEG---EENPDQ--- 366
Query: 148 QLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAG 207
P P P+ T + + AP PP +GA
Sbjct: 367 ------------PTDPGAGAEIPTSTA-DTSNSSNPAP---------------PPGEGAD 398
Query: 208 GKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPL 267
E ++E + R++DE+ +SP++ G PG PA
Sbjct: 399 DLEGEFTEETI---RNLDENYYDPYYDPTSSPSEIG-------------PGMPA------ 436
Query: 268 PVDFLSKVSTEIPASEPDGPSVGRA-KGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAA 326
+ + GP + KG+ A +E +E P + G A
Sbjct: 437 --------NQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPE----------GPAG 478
Query: 327 FPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT 386
PG PG GP+ + +P E+ P P +P M+
Sbjct: 479 LPGPPG----TMGPT-------GQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527
Query: 387 GSDDKKAK----TSTRSSAKTLKNRPCLSPKHPT-----PGSSDPLIQPSSPAVCPEP-- 435
G D +K ++ S A+ + + L+ + P G P+ P S + EP
Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587
Query: 436 --PSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKT- 492
P P+ V G G + G+DG + P P G +G +P +
Sbjct: 588 VGPQGPRGVQGPPGPAGKPGRRGRA--GSDGARGM--PGQTGPKGDRGFDGLAGLPGEKG 643
Query: 493 ---PPAPKTPPSSATKQVQRRPP-PAGPRSERGEPPKSGDRSGYSSPGSPGTPG 542
P P PP +R GPR GEP G PG PG PG
Sbjct: 644 HRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG 697
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 76.3 bits (186), Expect = 1e-13
Identities = 140/551 (25%), Positives = 179/551 (32%), Gaps = 129/551 (23%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA--GHVTQEPESGKVVQEGFLR 138
+ G PGK P P+G G TP L G+ + G+ G
Sbjct: 256 EAGKPGKAGERGPPG--PQGAR----GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 309
Query: 139 EPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQ 198
E G PG +G PG P GPR + TGP G R G+ Q
Sbjct: 310 ESGSPG-----ENGSPG----PMGPRGLPGERGRTGPAGAAGAR-----------GNDGQ 349
Query: 199 EGP--------PLKGAGGKERPGSKEEVD----------EDRDVDESSPQDSPPSKAS-- 238
GP P G G PG+K E + + +P P+ AS
Sbjct: 350 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 409
Query: 239 PAQDGRPPQTAAREATSI---PGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQ 295
P DG P + A I PGFP P P + P + P + KG+
Sbjct: 410 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG---PKGQTGEPGIAGFKGE 466
Query: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEP 354
P + G A GAPG G E + + GE + P
Sbjct: 467 QGP--------------------KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506
Query: 355 SEK-----------QPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKT 403
E+ A P+G P R P A G D + A+
Sbjct: 507 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA-----GPKGANGDPGRPGEPGLPGARG 561
Query: 404 LKNRPC-------LSP-----KHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGS 451
L RP + P + PG P P V P PK + + G
Sbjct: 562 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP--GPKGANGEPGKAGE 619
Query: 452 SGAKEMK----LKGADGKTKIATPRG-AAPPGQKGQANATRIPA-KTPPAPKTPPSSATK 505
G L G DG+T A P G A P G++G+ A + P P PP K
Sbjct: 620 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679
Query: 506 QVQRRPPP-------AGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP-TPPTRE 557
+ P GPR ERG P + G SPG+ G G R LP TP T
Sbjct: 680 PGDQGVPGEAGAPGLVGPRGERGFPGERG------SPGAQGLQGPR----GLPGTPGTDG 729
Query: 558 PKKVAVVRTPP 568
PK + PP
Sbjct: 730 PKGASGPAGPP 740
Score = 70.9 bits (172), Expect = 4e-12
Identities = 146/605 (24%), Positives = 194/605 (32%), Gaps = 108/605 (17%)
Query: 58 EPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDT-PSLED 116
EPG + P E P +GAPG E G E G+G P E
Sbjct: 457 EPGIAGFKGEQGPKGEP--GPAGPQGAPGPAGE-----EGKRGARGEPGGVGPIGPPGER 509
Query: 117 EAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMS----GMPGAPLLPEGPREATRQPSG 172
A G+ + G +G E GP GL+ + G PG P LP G R T +P
Sbjct: 510 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP-GARGLTGRPGD 568
Query: 173 TGPEDTEGGRHAPELLKHQLLGDLHQEGPP-LKGAGGKER----PGSKEEVDEDRDVDES 227
GP+ G AP G+ + GPP +GA G+ PG K E E
Sbjct: 569 AGPQGKVGPSGAP--------GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 620
Query: 228 SPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
+P + P +DG G E P P F P E P
Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 680
Query: 288 SVGRAKGQ-DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPG-EGPE--------- 336
G+ AP E ++ ++ G PG PG +GP+
Sbjct: 681 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 740
Query: 337 -ARGP-----------SLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKD 384
A+GP + G + D + EK P AP GK R L +
Sbjct: 741 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP-GKDGGR--GLTGPIGPPGPA 797
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPC----LSPKHPTPGSSDPLIQPSSPAVCPEPPSSPK 440
G + + + + + P P P + P A + + K
Sbjct: 798 GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK 857
Query: 441 HVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTP------- 493
+ G SGA G G T + P+GA G +G AT P
Sbjct: 858 GDAGAPGPQGPSGAP-----GPQGPTGVTGPKGAR--GAQGPPGATGFPGAAGRVGPPGS 910
Query: 494 ---PAPKTPPSSATKQVQRR------PP----------PAGPRSERGEPPKSGDRSGYSS 534
P P PP + K + PP PAGP E+GEP G
Sbjct: 911 NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP 970
Query: 535 PGSPGTPGSRSRT-----------PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPV 583
PG G G R P LP P+ EP K +P ++ R PV
Sbjct: 971 PGPQGLAGQRGIVGLPGQRGERGFPGLP-GPSGEPGKQG-------APGASGDRGPPGPV 1022
Query: 584 PMPDL 588
P L
Sbjct: 1023 GPPGL 1027
Score = 68.2 bits (165), Expect = 3e-11
Identities = 125/490 (25%), Positives = 157/490 (32%), Gaps = 82/490 (16%)
Query: 82 EGAPGKQAAAQPHTEI----PEGTTAEEAGIGDT-PSLEDEAAGHVTQEPESGKVVQEGF 136
EGAPGK I P G E+ +G P+ A G + E+G GF
Sbjct: 776 EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF 835
Query: 137 LREPGP---PGLSHQL----MSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLK 189
PG PG + G GAP P+GP A TG +G R A
Sbjct: 836 AGPPGADGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQGPTGVTGPKGARGA----- 889
Query: 190 HQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTA 249
+GPP G PG+ V S+ PP P+ G+
Sbjct: 890 ---------QGPP----GATGFPGAAGRVGPPG----SNGNPGPPGPPGPS--GKDGPKG 930
Query: 250 AREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP--DGPSVGRAKGQDAPLEFTFHVEI 307
AR + PG E + P + EP DGPS A+G P
Sbjct: 931 ARGDSGPPGRAGEPGLQGPAGPPGE------KGEPGDDGPS--GAEGPPGPQGLAG---- 978
Query: 308 TPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKP 367
Q+ G FPG PG E + + P P P G+P
Sbjct: 979 ----QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 1034
Query: 368 VSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPS 427
R S DG D A P +PG + P +
Sbjct: 1035 --------GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086
Query: 428 ----SPAVCPEPPSSPKHVSSVTSRTGSSGAK-------EMKLKGADGKTKIATPRGAAP 476
+ A P PS P + G G K E LKG G T + G P
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPG--P 1144
Query: 477 PGQKGQANATRIPAKTPPAPKTPPS----SATKQVQRRPPPAGPRSERGEPPKSGDRSGY 532
PG G A+ PA P P+ PP S P P GP RG ++G
Sbjct: 1145 PGPSGDQGASG-PAG-PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1202
Query: 533 SSPGSPGTPG 542
+PG PG PG
Sbjct: 1203 GNPGPPGPPG 1212
Score = 67.4 bits (163), Expect = 5e-11
Identities = 142/599 (23%), Positives = 201/599 (33%), Gaps = 99/599 (16%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDV 75
GT GL K GY +G+ A + +P E+GS P + P
Sbjct: 279 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP----MGPRGLPGERGR 334
Query: 76 TAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIG--DTPSLEDEAAGHVTQEPE--SGKV 131
T P GA G QP P G G G P + EA + PE G
Sbjct: 335 TGPAGAAGARGND--GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392
Query: 132 VQEGFLREPGPPGLSHQL-------------MSGMPGAPLLPEGPREATRQPSGTGPEDT 178
+ G PGP G S G+ GAP P GPR TGP
Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP-GPRGPPGPQGATGPLGP 451
Query: 179 EGGRHAPELLKHQLLGDLHQEGPP-------LKGAGGKE-RPGSKEEVDEDRDVDESSPQ 230
+G P + + G+ +G P G G+E + G++ E + +
Sbjct: 452 KGQTGEPGIAGFK--GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509
Query: 231 DSPPSKASPAQDG----------RPPQTAA--REATSIPGFPAEGAIPLPVDFLSKVSTE 278
+P ++ P QDG R P A + A PG P E +P +
Sbjct: 510 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 569
Query: 279 IPASE------------PDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAA 326
P + P P A+GQ + F + A+ E G+A
Sbjct: 570 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP---------GPKGANGEP--GKAG 618
Query: 327 FPGAPGEGPEARG-PSLGEDTKEADLPEPS----EKQPAAAPRGKPVSRVPQLKARMVSK 381
G PG P RG P +T A P P+ E+ AP +P
Sbjct: 619 EKGLPG-APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG 677
Query: 382 SKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKH 441
K G +A + + P G P P +P PK
Sbjct: 678 GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT-----DGPKG 732
Query: 442 VSSVTSRTGSSGAKEMK-LKGADGKTKIATPRG-AAPPGQKGQANATRIPAKT------- 492
S G+ G ++ + G G IA P+G G+KG A P K
Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA---PGKDGGRGLTG 789
Query: 493 PPAPKTPPSSATKQVQRRPP-PAGPRSERGEPPKSGDR-----SGYSS-PGSPGTPGSR 544
P P P + ++ + PP PAG RG P + G+ +G++ PG+ G PG++
Sbjct: 790 PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848
Score = 64.3 bits (155), Expect = 4e-10
Identities = 134/557 (24%), Positives = 179/557 (32%), Gaps = 89/557 (15%)
Query: 37 GDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAA-AQPHT 95
GD K P P EDG P A+ P P G PGK P
Sbjct: 567 GDAGPQGKVGPSGAPGEDGRPGPPGPQG-ARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 625
Query: 96 EIPEGTTAE--EAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL-------S 146
G + E G P AG + E G GF PGPPG
Sbjct: 626 PGLRGLPGKDGETGAAGPPG----PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 681
Query: 147 HQLMSGMPGAPLL--PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGP--- 201
Q + G GAP L P G R + G + +G R P G +GP
Sbjct: 682 DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--------GTPGTDGPKGA 733
Query: 202 --PLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGF 259
P G + PG + E + P+ +G P + R T G
Sbjct: 734 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 793
Query: 260 PAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSE 319
P + E P GP+ G A + AP E + +
Sbjct: 794 PGPAG----------ANGEKGEVGPPGPA-GSAGARGAPGE------------RGETGPP 830
Query: 320 EHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMV 379
G A PGA G+ P A+G GE ++ D P + P+ AP + + V K
Sbjct: 831 GPAGFAGPPGADGQ-PGAKGEQ-GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARG 888
Query: 380 SKSKDG-TGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP----------GSSDPLIQPSS 428
++ G TG + S N P P P G S P +
Sbjct: 889 AQGPPGATGFPGAAGRVGPPGS-----NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943
Query: 429 PAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP-PGQKGQANATR 487
P + + P+ P G SGA+ G G +A RG PGQ+G+
Sbjct: 944 PGL--QGPAGPPGEKGEPGDDGPSGAE-----GPPGPQGLAGQRGIVGLPGQRGERGFPG 996
Query: 488 IPAKT-PPAPKTPPSSATKQVQRRP--PPA--GPRSERGEPPKSGDRSGYSSPGSPGTPG 542
+P + P + P ++ + P PP GP E G G G+ G G
Sbjct: 997 LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056
Query: 543 SRSRT-----PSLPTPP 554
R T P P PP
Sbjct: 1057 DRGETGAVGAPGAPGPP 1073
Score = 52.4 bits (124), Expect = 2e-06
Identities = 98/420 (23%), Positives = 145/420 (34%), Gaps = 60/420 (14%)
Query: 127 ESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPE 186
++G V+ + + E LS ++ G P+ P A+ QP GP+ +G
Sbjct: 58 DTGTVLCDDIICEDVKDCLSPEIPFG-ECCPICPTDLATASGQP---GPKGQKGEP---- 109
Query: 187 LLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPP 246
GD+ P KG G + P ++ DR + + +P + + G P
Sbjct: 110 -------GDIKDIVGP-KGPPGPQGPAGEQGPRGDRG--DKGEKGAPGPRGRDGEPGTPG 159
Query: 247 QTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVE 306
PG P G +F ++++ + G +G +G P+
Sbjct: 160 NPGPPGPPGPPGPPGLGG-----NFAAQMAGGFD-EKAGGAQLGVMQGPMGPMG------ 207
Query: 307 ITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK 366
P A + G PG PGE P GP +G +P + A P GK
Sbjct: 208 --PRGPPGPAGAPGPQGFQGNPGEPGE-PGVSGP-MGPRGPPGPPGKPGDDGEAGKP-GK 262
Query: 367 PVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQP 426
R P G T K + P L G+ +
Sbjct: 263 AGERGPP-----------GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311
Query: 427 SSPAVCPEP-PSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANA 485
SP P P P+ + RTG +GA + G DG+ P A PPG G A
Sbjct: 312 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR--GNDGQ-----PGPAGPPGPVGPAGG 364
Query: 486 TRIPAKTPPAPKTPPSSATKQVQRRPPPA-GPRSERGEPPKSGDRSGYSSPGSPGTPGSR 544
P + P+ A R P A GPR E G P G +PG+ G PG++
Sbjct: 365 PGFPGAPGAKGEAGPTGA-----RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 419
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/92 (33%), Positives = 39/92 (42%), Gaps = 15/92 (16%)
Query: 466 TKIATPRGA-APPGQKGQANATR--IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGE 522
T +AT G P GQKG+ + + K PP P+ P P G R ++GE
Sbjct: 91 TDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG--------PRGDRGDKGE 142
Query: 523 PPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
G R PG+PG PG P P PP
Sbjct: 143 KGAPGPRGRDGEPGTPGNPG----PPGPPGPP 170
Score = 35.0 bits (79), Expect = 0.27
Identities = 41/173 (23%), Positives = 58/173 (33%), Gaps = 21/173 (12%)
Query: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK-------EMKLKGADGKTKIA 469
PG S P+ P P PP P + G +G + G G +
Sbjct: 233 PGVSGPM----GPRGPPGPPGKPGD-DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK 287
Query: 470 TPRG-AAPPGQKGQANATRIPAKT-------PPAPKTPPSSATKQVQRRPP-PAGPRSER 520
RG G KG+A A + ++ P P P ++ + P AG R
Sbjct: 288 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND 347
Query: 521 GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSS 573
G+P +G G PG PG+ R P+ R P +P S
Sbjct: 348 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 400
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 76.3 bits (186), Expect = 1e-13
Identities = 140/551 (25%), Positives = 179/551 (32%), Gaps = 129/551 (23%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA--GHVTQEPESGKVVQEGFLR 138
+ G PGK P P+G G TP L G+ + G+ G
Sbjct: 187 EAGKPGKAGERGPPG--PQGAR----GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 240
Query: 139 EPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQ 198
E G PG +G PG P GPR + TGP G R G+ Q
Sbjct: 241 ESGSPG-----ENGSPG----PMGPRGLPGERGRTGPAGAAGAR-----------GNDGQ 280
Query: 199 EGP--------PLKGAGGKERPGSKEEVD----------EDRDVDESSPQDSPPSKAS-- 238
GP P G G PG+K E + + +P P+ AS
Sbjct: 281 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340
Query: 239 PAQDGRPPQTAAREATSI---PGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQ 295
P DG P + A I PGFP P P + P + P + KG+
Sbjct: 341 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG---PKGQTGEPGIAGFKGE 397
Query: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEP 354
P + G A GAPG G E + + GE + P
Sbjct: 398 QGP--------------------KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 437
Query: 355 SEK-----------QPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKT 403
E+ A P+G P R P A G D + A+
Sbjct: 438 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA-----GPKGANGDPGRPGEPGLPGARG 492
Query: 404 LKNRPC-------LSP-----KHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGS 451
L RP + P + PG P P V P PK + + G
Sbjct: 493 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP--GPKGANGEPGKAGE 550
Query: 452 SGAKEMK----LKGADGKTKIATPRG-AAPPGQKGQANATRIPA-KTPPAPKTPPSSATK 505
G L G DG+T A P G A P G++G+ A + P P PP K
Sbjct: 551 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 610
Query: 506 QVQRRPPP-------AGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP-TPPTRE 557
+ P GPR ERG P + G SPG+ G G R LP TP T
Sbjct: 611 PGDQGVPGEAGAPGLVGPRGERGFPGERG------SPGAQGLQGPR----GLPGTPGTDG 660
Query: 558 PKKVAVVRTPP 568
PK + PP
Sbjct: 661 PKGASGPAGPP 671
Score = 70.9 bits (172), Expect = 4e-12
Identities = 146/605 (24%), Positives = 194/605 (32%), Gaps = 108/605 (17%)
Query: 58 EPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDT-PSLED 116
EPG + P E P +GAPG E G E G+G P E
Sbjct: 388 EPGIAGFKGEQGPKGEP--GPAGPQGAPGPAGE-----EGKRGARGEPGGVGPIGPPGER 440
Query: 117 EAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMS----GMPGAPLLPEGPREATRQPSG 172
A G+ + G +G E GP GL+ + G PG P LP G R T +P
Sbjct: 441 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP-GARGLTGRPGD 499
Query: 173 TGPEDTEGGRHAPELLKHQLLGDLHQEGPP-LKGAGGKER----PGSKEEVDEDRDVDES 227
GP+ G AP G+ + GPP +GA G+ PG K E E
Sbjct: 500 AGPQGKVGPSGAP--------GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 551
Query: 228 SPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
+P + P +DG G E P P F P E P
Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 611
Query: 288 SVGRAKGQ-DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPG-EGPE--------- 336
G+ AP E ++ ++ G PG PG +GP+
Sbjct: 612 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 671
Query: 337 -ARGP-----------SLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKD 384
A+GP + G + D + EK P AP GK R L +
Sbjct: 672 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP-GKDGGR--GLTGPIGPPGPA 728
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPC----LSPKHPTPGSSDPLIQPSSPAVCPEPPSSPK 440
G + + + + + P P P + P A + + K
Sbjct: 729 GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK 788
Query: 441 HVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTP------- 493
+ G SGA G G T + P+GA G +G AT P
Sbjct: 789 GDAGAPGPQGPSGAP-----GPQGPTGVTGPKGAR--GAQGPPGATGFPGAAGRVGPPGS 841
Query: 494 ---PAPKTPPSSATKQVQRR------PP----------PAGPRSERGEPPKSGDRSGYSS 534
P P PP + K + PP PAGP E+GEP G
Sbjct: 842 NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP 901
Query: 535 PGSPGTPGSRSRT-----------PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPV 583
PG G G R P LP P+ EP K +P ++ R PV
Sbjct: 902 PGPQGLAGQRGIVGLPGQRGERGFPGLP-GPSGEPGKQG-------APGASGDRGPPGPV 953
Query: 584 PMPDL 588
P L
Sbjct: 954 GPPGL 958
Score = 68.9 bits (167), Expect = 2e-11
Identities = 136/575 (23%), Positives = 180/575 (31%), Gaps = 83/575 (14%)
Query: 78 PLVDEGAPG--KQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA----GHVTQEPESGKV 131
P +G PG K P+G E+ GD ++ A G + G
Sbjct: 33 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 92
Query: 132 VQEGFLREPGPPGLSHQLMSGMPGA---------------PLLPEGPREATRQPSGTGPE 176
G PGPPGL + M G P+ P GPR GP+
Sbjct: 93 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQ 152
Query: 177 DTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSK 236
+G P + + G + GPP G +PG E + E P ++
Sbjct: 153 GFQGNPGEPG--EPGVSGPMGPRGPP----GPPGKPGDDGEAGKPGKAGERGPPGPQGAR 206
Query: 237 ASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP-SVGRAKGQ 295
P G P R + G E P V S E + P GP + +G+
Sbjct: 207 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAP-GVKGESGSPGENGSPGPMGPRGLPGERGR 265
Query: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRA---AFPGAPGEGPE-----ARGPSLGEDTK 347
P + Q A +G A FPGAPG E ARGP G
Sbjct: 266 TGPAGAA--GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE-GAQGP 322
Query: 348 EADLPEPSEKQPAAAPRGKPVSRVPQLKA----------------RMVSKSKDGTGSDDK 391
+ P PA A +P K R + TG
Sbjct: 323 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 382
Query: 392 KAKTSTRSSA-----KTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEP----PSSPKHV 442
K +T A + K P P P G+ P + EP P P
Sbjct: 383 KGQTGEPGIAGFKGEQGPKGEP--GPAGP-QGAPGPAGEEGKRGARGEPGGVGPIGPPGE 439
Query: 443 SSVTSRTGSSG----AKEMKLKGADGKTKIATPRGA-------APPGQKGQANATRIPAK 491
G G A G G + +A P+GA PG G T P
Sbjct: 440 RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 499
Query: 492 TPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRS--RTPS 549
P K PS A + RP P GP+ RG+P G + G PG G + P
Sbjct: 500 AGPQGKVGPSGAPGE-DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPG 558
Query: 550 LPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 584
L P ++ + A P P+ + Q AP P
Sbjct: 559 LRGLPGKDGETGAAGPPGPAGPAGERGE-QGAPGP 592
Score = 68.2 bits (165), Expect = 3e-11
Identities = 125/490 (25%), Positives = 157/490 (32%), Gaps = 82/490 (16%)
Query: 82 EGAPGKQAAAQPHTEI----PEGTTAEEAGIGDT-PSLEDEAAGHVTQEPESGKVVQEGF 136
EGAPGK I P G E+ +G P+ A G + E+G GF
Sbjct: 707 EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF 766
Query: 137 LREPGP---PGLSHQL----MSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLK 189
PG PG + G GAP P+GP A TG +G R A
Sbjct: 767 AGPPGADGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQGPTGVTGPKGARGA----- 820
Query: 190 HQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTA 249
+GPP G PG+ V S+ PP P+ G+
Sbjct: 821 ---------QGPP----GATGFPGAAGRVGPPG----SNGNPGPPGPPGPS--GKDGPKG 861
Query: 250 AREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP--DGPSVGRAKGQDAPLEFTFHVEI 307
AR + PG E + P + EP DGPS A+G P
Sbjct: 862 ARGDSGPPGRAGEPGLQGPAGPPGE------KGEPGDDGPS--GAEGPPGPQGLAG---- 909
Query: 308 TPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKP 367
Q+ G FPG PG E + + P P P G+P
Sbjct: 910 ----QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 965
Query: 368 VSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPS 427
R S DG D A P +PG + P +
Sbjct: 966 --------GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017
Query: 428 ----SPAVCPEPPSSPKHVSSVTSRTGSSGAK-------EMKLKGADGKTKIATPRGAAP 476
+ A P PS P + G G K E LKG G T + G P
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPG--P 1075
Query: 477 PGQKGQANATRIPAKTPPAPKTPPS----SATKQVQRRPPPAGPRSERGEPPKSGDRSGY 532
PG G A+ PA P P+ PP S P P GP RG ++G
Sbjct: 1076 PGPSGDQGASG-PAG-PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1133
Query: 533 SSPGSPGTPG 542
+PG PG PG
Sbjct: 1134 GNPGPPGPPG 1143
Score = 67.4 bits (163), Expect = 5e-11
Identities = 142/599 (23%), Positives = 201/599 (33%), Gaps = 99/599 (16%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDV 75
GT GL K GY +G+ A + +P E+GS P + P
Sbjct: 210 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP----MGPRGLPGERGR 265
Query: 76 TAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIG--DTPSLEDEAAGHVTQEPE--SGKV 131
T P GA G QP P G G G P + EA + PE G
Sbjct: 266 TGPAGAAGARGND--GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 323
Query: 132 VQEGFLREPGPPGLSHQL-------------MSGMPGAPLLPEGPREATRQPSGTGPEDT 178
+ G PGP G S G+ GAP P GPR TGP
Sbjct: 324 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP-GPRGPPGPQGATGPLGP 382
Query: 179 EGGRHAPELLKHQLLGDLHQEGPP-------LKGAGGKE-RPGSKEEVDEDRDVDESSPQ 230
+G P + + G+ +G P G G+E + G++ E + +
Sbjct: 383 KGQTGEPGIAGFK--GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440
Query: 231 DSPPSKASPAQDG----------RPPQTAA--REATSIPGFPAEGAIPLPVDFLSKVSTE 278
+P ++ P QDG R P A + A PG P E +P +
Sbjct: 441 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500
Query: 279 IPASE------------PDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAA 326
P + P P A+GQ + F + A+ E G+A
Sbjct: 501 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP---------GPKGANGEP--GKAG 549
Query: 327 FPGAPGEGPEARG-PSLGEDTKEADLPEPS----EKQPAAAPRGKPVSRVPQLKARMVSK 381
G PG P RG P +T A P P+ E+ AP +P
Sbjct: 550 EKGLPG-APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG 608
Query: 382 SKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKH 441
K G +A + + P G P P +P PK
Sbjct: 609 GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT-----DGPKG 663
Query: 442 VSSVTSRTGSSGAKEMK-LKGADGKTKIATPRG-AAPPGQKGQANATRIPAKT------- 492
S G+ G ++ + G G IA P+G G+KG A P K
Sbjct: 664 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA---PGKDGGRGLTG 720
Query: 493 PPAPKTPPSSATKQVQRRPP-PAGPRSERGEPPKSGDR-----SGYSS-PGSPGTPGSR 544
P P P + ++ + PP PAG RG P + G+ +G++ PG+ G PG++
Sbjct: 721 PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779
Score = 64.3 bits (155), Expect = 4e-10
Identities = 134/557 (24%), Positives = 179/557 (32%), Gaps = 89/557 (15%)
Query: 37 GDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAA-AQPHT 95
GD K P P EDG P A+ P P G PGK P
Sbjct: 498 GDAGPQGKVGPSGAPGEDGRPGPPGPQG-ARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 556
Query: 96 EIPEGTTAE--EAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL-------S 146
G + E G P AG + E G GF PGPPG
Sbjct: 557 PGLRGLPGKDGETGAAGPPG----PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 612
Query: 147 HQLMSGMPGAPLL--PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGP--- 201
Q + G GAP L P G R + G + +G R P G +GP
Sbjct: 613 DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--------GTPGTDGPKGA 664
Query: 202 --PLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGF 259
P G + PG + E + P+ +G P + R T G
Sbjct: 665 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 724
Query: 260 PAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSE 319
P + E P GP+ G A + AP E + +
Sbjct: 725 PGPAG----------ANGEKGEVGPPGPA-GSAGARGAPGE------------RGETGPP 761
Query: 320 EHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMV 379
G A PGA G+ P A+G GE ++ D P + P+ AP + + V K
Sbjct: 762 GPAGFAGPPGADGQ-PGAKGEQ-GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARG 819
Query: 380 SKSKDG-TGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP----------GSSDPLIQPSS 428
++ G TG + S N P P P G S P +
Sbjct: 820 AQGPPGATGFPGAAGRVGPPGS-----NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874
Query: 429 PAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP-PGQKGQANATR 487
P + + P+ P G SGA+ G G +A RG PGQ+G+
Sbjct: 875 PGL--QGPAGPPGEKGEPGDDGPSGAE-----GPPGPQGLAGQRGIVGLPGQRGERGFPG 927
Query: 488 IPAKT-PPAPKTPPSSATKQVQRRP--PPA--GPRSERGEPPKSGDRSGYSSPGSPGTPG 542
+P + P + P ++ + P PP GP E G G G+ G G
Sbjct: 928 LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987
Query: 543 SRSRT-----PSLPTPP 554
R T P P PP
Sbjct: 988 DRGETGAVGAPGAPGPP 1004
Score = 43.9 bits (102), Expect = 6e-04
Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 14/85 (16%)
Query: 472 RGAAPPGQKGQANATR--IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDR 529
R P GQKG+ + + K PP P+ P P G R ++GE G R
Sbjct: 29 RQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG--------PRGDRGDKGEKGAPGPR 80
Query: 530 SGYSSPGSPGTPGSRSRTPSLPTPP 554
PG+PG PG P P PP
Sbjct: 81 GRDGEPGTPGNPG----PPGPPGPP 101
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 75.9 bits (185), Expect = 1e-13
Identities = 116/479 (24%), Positives = 165/479 (34%), Gaps = 66/479 (13%)
Query: 170 PSGTGPEDTEGGRHAPELLKHQLLGDLH---QEGPPLKGAGGKERPG-SKEEVDEDRDVD 225
P G+ P +P + + Q L H Q G P G +PG SK + +
Sbjct: 67 PKGSVPP---AAAESPSMHRKQELDSSHPPKQSGRP-PDPGRPAQPGLSKSRTTDTFRSE 122
Query: 226 ESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPD 285
+ P SP + + R +++ +PGF +E V+ LS VS+ + P
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSE------VNALSAVSSVVNKFNPF 176
Query: 286 GPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGED 345
Q+ E T ++ VQKEQ E + P P+ +GP G D
Sbjct: 177 DLISDSEASQE---ETTKKQKV---VQKEQGKPEGIIKPPLQQQPPKPIPKQQGP--GRD 228
Query: 346 TKEAD---------LPEPSEKQPAAAPRGKPV---SRVPQLKARMVSKSKDGTGSDDKKA 393
+ D PE + QP GKP+ ++ PQ + +D + K+A
Sbjct: 229 PLQQDGTPKSISSQQPEKIKSQPPGT--GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 394 KTSTRSSAKTLKNRPCLSP-KHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
S K P P + PTPG P QP P P P S +T
Sbjct: 287 DIVRGESVKPSLPSPSKPPIQQPTPGKP-PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ 345
Query: 453 GAKEMKLKGADGKTKI-ATPRGAAPPGQKGQANATRIPAKTPPAPKT---PPSSATKQVQ 508
G TK A P G A P Q + P+ P PK PP Q
Sbjct: 346 PGTVKPPVQPPGTTKPPAQPLGPAKP--PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403
Query: 509 RRPPPAGPRSERGEPPKSGDRSGYSSPGS-----------------PGTPGSRSRTPSLP 551
+ P P + G P + G SP P +T +
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463
Query: 552 TPPTREPKKV-AVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGK 609
T PT+ P ++ + PP+ P AK P K + GST+ QPG K
Sbjct: 464 TGPTKPPSQLPGPAKPPPQQPGPAKP----PPQQPGSAKPPSQQPGSTKPPPQQPGPAK 518
Score = 70.9 bits (172), Expect = 4e-12
Identities = 126/575 (21%), Positives = 196/575 (34%), Gaps = 70/575 (12%)
Query: 52 TEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ-PHTEIP-EGTTAEEAGIG 109
T+ +++PG+ + T + PL P +Q ++ P +E P A+ G+G
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 110 DTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMS-GMPGAPLLPEGPREATR 168
TP+ + A TQ+ + K + + PGL + G P+ GP +
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQ-------QPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
Query: 169 QPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGK---ERPGSKEEVDEDRDVD 225
Q +G G T + P QL G + PP + K ++PGS + +
Sbjct: 452 QQAGPGK--TSAQQTGPTKPPSQLPGPA--KPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 226 ESSPQDSPPSKASPAQDG--RPP--QTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPA 281
+ PQ P+K SP Q G +PP Q + + ++ PA+ + +S+ + P
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 282 SEPD-GPSVGRAKGQDAP---------LEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAP 331
P PS + Q P E HV N F P
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627
Query: 332 GEGPEARGPSLGEDTKEA---DL-PEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTG 387
L K A DL P PS Q P+LK V+ + +
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ-------------PKLKTAPVTTTSAVSK 674
Query: 388 SDDKKAKTSTRSSA---KTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSS 444
S + +TS + A + L P PK P P P + S A +PP +
Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKAP--EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 445 VTSRTGSSGAKEMKLKGADGKTK-----------IATPRGAAPPGQKGQANATRIPAKTP 493
+ S +++ K AD K K +++ P ++ KT
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 494 PAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSL--P 551
P KT + ++ P + P + D S PG P S S+ P
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG----PSSESKGQKQVDP 848
Query: 552 TPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
EPKK +P T P P P
Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Score = 64.3 bits (155), Expect = 4e-10
Identities = 136/644 (21%), Positives = 214/644 (33%), Gaps = 78/644 (12%)
Query: 45 ESPLQTPTEDGSEEPGSETSDAKSTPTAEDV------------TAPLVDEGAPGKQAAAQ 92
+ P QTP D ++ P + T A+ V + P + + PGK A Q
Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQ 318
Query: 93 PHTEI----PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQE--GFLREPGPPGLS 146
P E P A+ +G+ + + Q P + K + G + P S
Sbjct: 319 PGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS 378
Query: 147 HQLMSGMPGAPLLPEGP---REATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGP-- 201
+ S PG L + P + +QP P + G P + L GP
Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438
Query: 202 -PLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDG--RPPQTAAREATSIPG 258
P++ G + P Q + P K S Q G +PP A P
Sbjct: 439 TPVQQPGPGKIPA----------------QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
P P +K ++ P S P Q P + + + +Q S
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ------QPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 319 EEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLP--EPSEKQPAAAPRGK---PVSRVPQ 373
+ + P P + S K P PS KQP + K P+ +
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTE 596
Query: 374 LKARMVSKSKDGTGSDDKKAKTS-----TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSS 428
L + K+ T ++ + S +K CL+ + D PSS
Sbjct: 597 LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS 656
Query: 429 PAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIA-TPRGAAPPGQKGQANATR 487
P P+ ++P +S S++ + K A K ++ P PP Q
Sbjct: 657 PQ--PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHG 714
Query: 488 IP---AKTP--------PAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPG 536
P AK P PAP PS ++Q + P+ + P + S S+
Sbjct: 715 SPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 537 SPGTPGSR--SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSK 594
P P S+ S+ TPP + PP + + P P D K +
Sbjct: 775 KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834
Query: 595 IGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGG 638
S+E+ G +V + KK + Q+K K + K +P G
Sbjct: 835 GPSSES----KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG 874
Score = 63.5 bits (153), Expect = 7e-10
Identities = 142/659 (21%), Positives = 224/659 (33%), Gaps = 137/659 (20%)
Query: 47 PLQTPTED-GSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEE 105
P + PT+ G+ +P ++ +S A T V + PGK A Q P T+A++
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG---PGKTSAQQ 463
Query: 106 AGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPRE 165
G PS A Q+P K + +PG Q P P +
Sbjct: 464 TGPTKPPSQLPGPAKPPPQQPGPAKPPPQ----QPGSAKPPSQQPGSTKPPPQQPGPAKP 519
Query: 166 ATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVD 225
+ +QP T P + G P Q+ P K + + S + V +
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSA----------QQPSPAKPSAQQ----STKPVSQTGSGK 565
Query: 226 ESSPQDSPPSKASPAQDGRP----------------PQTA--------AREATSIPGFPA 261
P PS P G P P+ A S+ GF
Sbjct: 566 PLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP 625
Query: 262 EGAIPLPVDFLS---KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHV-EITPNVQ----K 313
+ ++L ++ + PS + K + AP+ T V + +P Q K
Sbjct: 626 NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPK 685
Query: 314 EQAHSEEHLGRAAFP-------------GAPG----EGPEARGPSLGEDTKEADLPEPSE 356
+ A ++ L +A P G+P + PEA S KE +P +
Sbjct: 686 KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD 745
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT 416
K P A + K V +VS S T D +K +++ KT P L
Sbjct: 746 KAPVADDKPKQPKMVKPT-TDLVSSSSATTKPDIPSSKVQSQAEEKTT---PPLKTDSAK 801
Query: 417 PGSSDP----LIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEM-----KLKGADGKTK 467
P S P + P P P S K +S + S G K++ K + +TK
Sbjct: 802 PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861
Query: 468 IAT-------PRGA-APPGQKGQANAT-RIPAKTPP-----------------APKTPP- 500
++ P+G+ PPG + A T P ++P APK+ P
Sbjct: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
Query: 501 ------------------SSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSP----GSP 538
S A+ + P GP S+ G S P G P
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQP-GPHSQSGPGAPMKQAPAPSQPPTSQGPP 980
Query: 539 GTPGSRSRTPSLPTPPTREPKKVAVVRTPPK---SPSSAKSRLQTAPVPMPDLKNVKSK 594
+ G P+ P +E K A + PK +P+ ++ + P P+ D K++ ++
Sbjct: 981 KSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 57.4 bits (137), Expect = 5e-08
Identities = 87/403 (21%), Positives = 132/403 (32%), Gaps = 46/403 (11%)
Query: 229 PQDSPPSKASPAQDGRPPQTAAREATSIP------GFPAEGAIPLPVDFLSKVSTEIPAS 282
P+ P + QDG P ++++ I G P +G P +K+ + AS
Sbjct: 220 PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 283 EPDGPSVGRAKGQDAPLEFTFHVEIT---PNVQKEQAHSEEHLGRAAFPGAPGEGPEARG 339
P +G+ + P K A H P P P
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
Query: 340 PSLGED--TKEADLPEPSEKQPAAAPRG------------KPVSRVPQLKARMVSKSKDG 385
L + T + + P +P A P G KP S P KA
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 386 TGSDDK---KAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHV 442
T + K T + K L +P L PG + +Q P P + P
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 443 SSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502
S+ +TG + K K P A PP Q Q + + P++ P + K PP
Sbjct: 460 SA--QQTGPT--KPPSQLPGPAKPPPQQPGPAKPPPQ--QPGSAKPPSQQPGSTKPPP-- 511
Query: 503 ATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVA 562
++P PA P ++ K + S+ S P + T P +
Sbjct: 512 ------QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
Query: 563 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 605
++ P SPS+ + Q P K + +TE L H P
Sbjct: 566 PLQPPTVSPSAKQPPSQGLP------KTICPLCNTTELLLHVP 602
Score = 46.2 bits (108), Expect = 1e-04
Identities = 68/255 (26%), Positives = 96/255 (37%), Gaps = 47/255 (18%)
Query: 336 EARGPSLGEDTKEADLPEPSEKQPAAAPRG--------KPVS--RVPQLKARMVSKS--- 382
+AR G+ EAD +P K + A + +PV R P ++AR+ +K
Sbjct: 3491 KARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEII 3550
Query: 383 ----------KDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP---GSSDPLIQPSSP 429
K G+ +A + T+S P K PTP G S L S+
Sbjct: 3551 KHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTV 3610
Query: 430 AVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIP 489
+ P PP SPK + S S A L+ A + P +P Q
Sbjct: 3611 QLAPSPPKSPKVLYSPISPLSPGKA----LESAFVPYEKPLPDDISP-----QKVLHPDM 3661
Query: 490 AKTPPA-PKTPPSSATKQVQRR---PPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRS 545
AK PPA PKT K +QR P P P ++ GY++ GS S +
Sbjct: 3662 AKVPPASPKT-----AKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGA 3716
Query: 546 RTP---SLPTPPTRE 557
+ +LP PP E
Sbjct: 3717 QKKVKRTLPNPPPEE 3731
Score = 40.0 bits (92), Expect = 0.008
Identities = 115/553 (20%), Positives = 189/553 (34%), Gaps = 90/553 (16%)
Query: 44 KESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTA 103
KE P + T+ + TP TA + P Q + +P E +
Sbjct: 852 KEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA---GQTVPTPQQSPKPQ-EQSRRFSL 907
Query: 104 EEAGIGDTPSLEDEAAGHVTQEPESGKVVQEG---------FLREPGPPGLSHQLMSGMP 154
I D P + QE +GK+ G + G PG Q SG P
Sbjct: 908 NLGSITDAPKSQPTTP----QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ--SG-P 960
Query: 155 GAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGS 214
GAP+ + P + + P+ GP + G + PP A K P
Sbjct: 961 GAPM-KQAPAPS-QPPTSQGPPKSTG------------------QAPP---APAKSIPVK 997
Query: 215 KEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
KE + E + +P K + + PP +++ S+ P + +P ++ K
Sbjct: 998 KETKAPAAEKLEPKAEQAPTVKRTETEKKPPP---IKDSKSLTAEPQKAVLPTKLEKSPK 1054
Query: 275 -------VSTEIPASEPDGPSVG---RAKGQDAPL---EFTFHVE-----ITPNVQKEQA 316
TE+ D P+ K Q L T H+ + N Q ++A
Sbjct: 1055 PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRA 1114
Query: 317 HSEEHLGRAAFPGAPGEGPEARG---PSLGEDTKEADLPE-----------PSEKQPAAA 362
S + P AP GP+A P+ K A P+ +E +
Sbjct: 1115 ISGQLGDIRKMPPAPS-GPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVIL 1173
Query: 363 PRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSD- 421
+ K + ++ MV+ + S +K K S K L L P+ S +
Sbjct: 1174 EKVKETLSMEKIPP-MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 422 -PLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
PL++ P PE + + +++ A+ K + G++
Sbjct: 1233 KPLLEEKKPT--PEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQ 1290
Query: 481 GQANATRIPAKTPPAPKTPPSSATKQVQRRP-PPAGPRSERGEP-----PKSGDRSGYSS 534
Q +P+ TP + TK ++ +P PP + ++ EP K D+S SS
Sbjct: 1291 PQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSS 1350
Query: 535 PGSPGTPGSRSRT 547
P +P S T
Sbjct: 1351 SQQPKSPQGLSDT 1363
Score = 39.3 bits (90), Expect = 0.014
Identities = 78/383 (20%), Positives = 125/383 (32%), Gaps = 73/383 (19%)
Query: 204 KGAGGKERPGSKEEVDEDRDVDES-SPQDSPPSKASPAQDGRPPQTAAR----EATSIPG 258
K + ++ K++ +D+ ++ P+ PP P G P A + ++ S P
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
P E ++P D + P ++ D P + L + P++ + S
Sbjct: 734 PPKEPSVPSEQD-------KAPVAD-DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 319 EEHLGRAAFPGAPGEGPEARGPSLGEDTKEAD---LPEPSEKQPAAAPRGKPVSRVPQLK 375
+ P P GE D +P P+ + G Q +
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ 845
Query: 376 ARMVSKSKDGTGSDDKKAKT--STRSSAKTL-KNRPCLSPKHPTPGSSDPLIQPSSP--- 429
V K ++ KKA+T S + AK + K P PT G + P Q S
Sbjct: 846 VDPVQKKEE-----PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 430 ----------AVCPEPPSSP-------------------KHVSSVTSRTGSSGAKEMKLK 460
++ P S P S++ S G G
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 461 GADGKTKIAT---PRGAAPPGQKGQA-----------NATRIPA--KTPPAPKTPPSSAT 504
GA K A P PP GQA T+ PA K P + P+
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
Query: 505 KQVQRRPPPA-GPRSERGEPPKS 526
+ +++PPP +S EP K+
Sbjct: 1021 TETEKKPPPIKDSKSLTAEPQKA 1043
Score = 37.4 bits (85), Expect = 0.054
Identities = 77/443 (17%), Positives = 148/443 (33%), Gaps = 58/443 (13%)
Query: 60 GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPS------ 113
G + + S+P + TAP+ A K ++ QP P+ A + + P
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSK-SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
Query: 114 LEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGT 173
L + H + ++ + + L +P PP + S AP+ + P++
Sbjct: 706 LVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQ-------- 756
Query: 174 GPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSP 233
P+++K P +K ++ + ++ + +P
Sbjct: 757 -----------PKMVK------------PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 234 PSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPS-VGRA 292
P K A +P Q+ + F ++ AIP P +S P+SE G V
Sbjct: 794 PLKTDSA---KPSQSFPPTGEKVSPFDSK-AIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 293 KGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPG----APGEGPEARGPSLGEDTKE 348
+ ++ P + + P+ + S G G P + P+ + S
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909
Query: 349 ADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRP 408
+ + + QP P+ ++ A + S++ + + + S +K
Sbjct: 910 GSITDAPKSQPTT-PQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ-- 966
Query: 409 CLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKI 468
P S P P + P +P V T + A++++ K T
Sbjct: 967 -------APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 469 ATPRGAAPPGQKGQANATRIPAK 491
T PP K + T P K
Sbjct: 1020 RTETEKKPPPIKDSKSLTAEPQK 1042
Score = 35.0 bits (79), Expect = 0.27
Identities = 51/216 (23%), Positives = 72/216 (33%), Gaps = 23/216 (10%)
Query: 366 KPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQ 425
KP S++P S K + RSS+ + +P P P P P
Sbjct: 2371 KPASQLPS--------GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
Query: 426 PSSPA---VCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQ 482
P P P+P PK +V S ++ D T + T G
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPL------FDAVTTLETTAVLRSNGLPVT 2476
Query: 483 ANATRIPAKTPPAPKTPPSSA--TKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
T P PP P + PS T + + PP P+ + P + + P G
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGL 2536
Query: 541 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKS 576
+ S T +L T + T P SP S KS
Sbjct: 2537 SLTSSMTLNLVTSADYKLPS----PTSPLSPHSNKS 2568
Score = 31.2 bits (69), Expect = 3.8
Identities = 54/224 (24%), Positives = 83/224 (37%), Gaps = 27/224 (12%)
Query: 380 SKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSP 439
S D D+ T +R A+ K ++ T PL + SS AV S
Sbjct: 3471 SVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTK----PLSKVSSIAVQTVAEISV 3526
Query: 440 KHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPP-APKT 498
+ T RT S A+ D K +I A KG + + A + +P+
Sbjct: 3527 QTEPVGTIRTPSIRAR------VDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQY 3580
Query: 499 PPSSATKQVQRRPPP----------AGPRSERGEPPKSGDRSGYS--SPGSPGTPGSRSR 546
+++ + ++RP P A + P + YS SP SPG +
Sbjct: 3581 LSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAF 3640
Query: 547 TP-SLPTPPTREPKKVA---VVRTPPKSPSSAKSRLQTAPVPMP 586
P P P P+KV + + PP SP +AK ++ P P
Sbjct: 3641 VPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 75.9 bits (185), Expect = 1e-13
Identities = 116/479 (24%), Positives = 165/479 (34%), Gaps = 66/479 (13%)
Query: 170 PSGTGPEDTEGGRHAPELLKHQLLGDLH---QEGPPLKGAGGKERPG-SKEEVDEDRDVD 225
P G+ P +P + + Q L H Q G P G +PG SK + +
Sbjct: 67 PKGSVPP---AAAESPSMHRKQELDSSHPPKQSGRP-PDPGRPAQPGLSKSRTTDTFRSE 122
Query: 226 ESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPD 285
+ P SP + + R +++ +PGF +E V+ LS VS+ + P
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSE------VNALSAVSSVVNKFNPF 176
Query: 286 GPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGED 345
Q+ E T ++ VQKEQ E + P P+ +GP G D
Sbjct: 177 DLISDSEASQE---ETTKKQKV---VQKEQGKPEGIIKPPLQQQPPKPIPKQQGP--GRD 228
Query: 346 TKEAD---------LPEPSEKQPAAAPRGKPV---SRVPQLKARMVSKSKDGTGSDDKKA 393
+ D PE + QP GKP+ ++ PQ + +D + K+A
Sbjct: 229 PLQQDGTPKSISSQQPEKIKSQPPGT--GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 394 KTSTRSSAKTLKNRPCLSP-KHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
S K P P + PTPG P QP P P P S +T
Sbjct: 287 DIVRGESVKPSLPSPSKPPIQQPTPGKP-PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ 345
Query: 453 GAKEMKLKGADGKTKI-ATPRGAAPPGQKGQANATRIPAKTPPAPKT---PPSSATKQVQ 508
G TK A P G A P Q + P+ P PK PP Q
Sbjct: 346 PGTVKPPVQPPGTTKPPAQPLGPAKP--PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403
Query: 509 RRPPPAGPRSERGEPPKSGDRSGYSSPGS-----------------PGTPGSRSRTPSLP 551
+ P P + G P + G SP P +T +
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463
Query: 552 TPPTREPKKV-AVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGK 609
T PT+ P ++ + PP+ P AK P K + GST+ QPG K
Sbjct: 464 TGPTKPPSQLPGPAKPPPQQPGPAKP----PPQQPGSAKPPSQQPGSTKPPPQQPGPAK 518
Score = 70.9 bits (172), Expect = 4e-12
Identities = 126/575 (21%), Positives = 196/575 (34%), Gaps = 70/575 (12%)
Query: 52 TEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ-PHTEIP-EGTTAEEAGIG 109
T+ +++PG+ + T + PL P +Q ++ P +E P A+ G+G
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 110 DTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMS-GMPGAPLLPEGPREATR 168
TP+ + A TQ+ + K + + PGL + G P+ GP +
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQ-------QPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
Query: 169 QPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGK---ERPGSKEEVDEDRDVD 225
Q +G G T + P QL G + PP + K ++PGS + +
Sbjct: 452 QQAGPGK--TSAQQTGPTKPPSQLPGPA--KPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 226 ESSPQDSPPSKASPAQDG--RPP--QTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPA 281
+ PQ P+K SP Q G +PP Q + + ++ PA+ + +S+ + P
Sbjct: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 282 SEPD-GPSVGRAKGQDAP---------LEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAP 331
P PS + Q P E HV N F P
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627
Query: 332 GEGPEARGPSLGEDTKEA---DL-PEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTG 387
L K A DL P PS Q P+LK V+ + +
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ-------------PKLKTAPVTTTSAVSK 674
Query: 388 SDDKKAKTSTRSSA---KTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSS 444
S + +TS + A + L P PK P P P + S A +PP +
Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKAP--EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
Query: 445 VTSRTGSSGAKEMKLKGADGKTK-----------IATPRGAAPPGQKGQANATRIPAKTP 493
+ S +++ K AD K K +++ P ++ KT
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 494 PAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSL--P 551
P KT + ++ P + P + D S PG P S S+ P
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG----PSSESKGQKQVDP 848
Query: 552 TPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
EPKK +P T P P P
Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Score = 64.3 bits (155), Expect = 4e-10
Identities = 136/644 (21%), Positives = 214/644 (33%), Gaps = 78/644 (12%)
Query: 45 ESPLQTPTEDGSEEPGSETSDAKSTPTAEDV------------TAPLVDEGAPGKQAAAQ 92
+ P QTP D ++ P + T A+ V + P + + PGK A Q
Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQ 318
Query: 93 PHTEI----PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQE--GFLREPGPPGLS 146
P E P A+ +G+ + + Q P + K + G + P S
Sbjct: 319 PGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS 378
Query: 147 HQLMSGMPGAPLLPEGP---REATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGP-- 201
+ S PG L + P + +QP P + G P + L GP
Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438
Query: 202 -PLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDG--RPPQTAAREATSIPG 258
P++ G + P Q + P K S Q G +PP A P
Sbjct: 439 TPVQQPGPGKIPA----------------QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
P P +K ++ P S P Q P + + + +Q S
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ------QPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 319 EEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLP--EPSEKQPAAAPRGK---PVSRVPQ 373
+ + P P + S K P PS KQP + K P+ +
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTE 596
Query: 374 LKARMVSKSKDGTGSDDKKAKTS-----TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSS 428
L + K+ T ++ + S +K CL+ + D PSS
Sbjct: 597 LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS 656
Query: 429 PAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIA-TPRGAAPPGQKGQANATR 487
P P+ ++P +S S++ + K A K ++ P PP Q
Sbjct: 657 PQ--PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHG 714
Query: 488 IP---AKTP--------PAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPG 536
P AK P PAP PS ++Q + P+ + P + S S+
Sbjct: 715 SPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 537 SPGTPGSR--SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSK 594
P P S+ S+ TPP + PP + + P P D K +
Sbjct: 775 KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834
Query: 595 IGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGG 638
S+E+ G +V + KK + Q+K K + K +P G
Sbjct: 835 GPSSES----KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG 874
Score = 63.5 bits (153), Expect = 7e-10
Identities = 142/659 (21%), Positives = 224/659 (33%), Gaps = 137/659 (20%)
Query: 47 PLQTPTED-GSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEE 105
P + PT+ G+ +P ++ +S A T V + PGK A Q P T+A++
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG---PGKTSAQQ 463
Query: 106 AGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPRE 165
G PS A Q+P K + +PG Q P P +
Sbjct: 464 TGPTKPPSQLPGPAKPPPQQPGPAKPPPQ----QPGSAKPPSQQPGSTKPPPQQPGPAKP 519
Query: 166 ATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVD 225
+ +QP T P + G P Q+ P K + + S + V +
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSA----------QQPSPAKPSAQQ----STKPVSQTGSGK 565
Query: 226 ESSPQDSPPSKASPAQDGRP----------------PQTA--------AREATSIPGFPA 261
P PS P G P P+ A S+ GF
Sbjct: 566 PLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP 625
Query: 262 EGAIPLPVDFLS---KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHV-EITPNVQ----K 313
+ ++L ++ + PS + K + AP+ T V + +P Q K
Sbjct: 626 NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPK 685
Query: 314 EQAHSEEHLGRAAFP-------------GAPG----EGPEARGPSLGEDTKEADLPEPSE 356
+ A ++ L +A P G+P + PEA S KE +P +
Sbjct: 686 KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD 745
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT 416
K P A + K V +VS S T D +K +++ KT P L
Sbjct: 746 KAPVADDKPKQPKMVKPT-TDLVSSSSATTKPDIPSSKVQSQAEEKTT---PPLKTDSAK 801
Query: 417 PGSSDP----LIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEM-----KLKGADGKTK 467
P S P + P P P S K +S + S G K++ K + +TK
Sbjct: 802 PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861
Query: 468 IAT-------PRGA-APPGQKGQANAT-RIPAKTPP-----------------APKTPP- 500
++ P+G+ PPG + A T P ++P APK+ P
Sbjct: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
Query: 501 ------------------SSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSP----GSP 538
S A+ + P GP S+ G S P G P
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQP-GPHSQSGPGAPMKQAPAPSQPPTSQGPP 980
Query: 539 GTPGSRSRTPSLPTPPTREPKKVAVVRTPPK---SPSSAKSRLQTAPVPMPDLKNVKSK 594
+ G P+ P +E K A + PK +P+ ++ + P P+ D K++ ++
Sbjct: 981 KSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 57.4 bits (137), Expect = 5e-08
Identities = 87/403 (21%), Positives = 132/403 (32%), Gaps = 46/403 (11%)
Query: 229 PQDSPPSKASPAQDGRPPQTAAREATSIP------GFPAEGAIPLPVDFLSKVSTEIPAS 282
P+ P + QDG P ++++ I G P +G P +K+ + AS
Sbjct: 220 PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 283 EPDGPSVGRAKGQDAPLEFTFHVEIT---PNVQKEQAHSEEHLGRAAFPGAPGEGPEARG 339
P +G+ + P K A H P P P
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
Query: 340 PSLGED--TKEADLPEPSEKQPAAAPRG------------KPVSRVPQLKARMVSKSKDG 385
L + T + + P +P A P G KP S P KA
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 386 TGSDDK---KAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHV 442
T + K T + K L +P L PG + +Q P P + P
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 443 SSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502
S+ +TG + K K P A PP Q Q + + P++ P + K PP
Sbjct: 460 SA--QQTGPT--KPPSQLPGPAKPPPQQPGPAKPPPQ--QPGSAKPPSQQPGSTKPPP-- 511
Query: 503 ATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVA 562
++P PA P ++ K + S+ S P + T P +
Sbjct: 512 ------QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
Query: 563 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 605
++ P SPS+ + Q P K + +TE L H P
Sbjct: 566 PLQPPTVSPSAKQPPSQGLP------KTICPLCNTTELLLHVP 602
Score = 46.2 bits (108), Expect = 1e-04
Identities = 68/255 (26%), Positives = 96/255 (37%), Gaps = 47/255 (18%)
Query: 336 EARGPSLGEDTKEADLPEPSEKQPAAAPRG--------KPVS--RVPQLKARMVSKS--- 382
+AR G+ EAD +P K + A + +PV R P ++AR+ +K
Sbjct: 3491 KARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEII 3550
Query: 383 ----------KDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP---GSSDPLIQPSSP 429
K G+ +A + T+S P K PTP G S L S+
Sbjct: 3551 KHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTV 3610
Query: 430 AVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIP 489
+ P PP SPK + S S A L+ A + P +P Q
Sbjct: 3611 QLAPSPPKSPKVLYSPISPLSPGKA----LESAFVPYEKPLPDDISP-----QKVLHPDM 3661
Query: 490 AKTPPA-PKTPPSSATKQVQRR---PPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRS 545
AK PPA PKT K +QR P P P ++ GY++ GS S +
Sbjct: 3662 AKVPPASPKT-----AKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGA 3716
Query: 546 RTP---SLPTPPTRE 557
+ +LP PP E
Sbjct: 3717 QKKVKRTLPNPPPEE 3731
Score = 40.0 bits (92), Expect = 0.008
Identities = 115/553 (20%), Positives = 189/553 (34%), Gaps = 90/553 (16%)
Query: 44 KESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTA 103
KE P + T+ + TP TA + P Q + +P E +
Sbjct: 852 KEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA---GQTVPTPQQSPKPQ-EQSRRFSL 907
Query: 104 EEAGIGDTPSLEDEAAGHVTQEPESGKVVQEG---------FLREPGPPGLSHQLMSGMP 154
I D P + QE +GK+ G + G PG Q SG P
Sbjct: 908 NLGSITDAPKSQPTTP----QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ--SG-P 960
Query: 155 GAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGS 214
GAP+ + P + + P+ GP + G + PP A K P
Sbjct: 961 GAPM-KQAPAPS-QPPTSQGPPKSTG------------------QAPP---APAKSIPVK 997
Query: 215 KEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
KE + E + +P K + + PP +++ S+ P + +P ++ K
Sbjct: 998 KETKAPAAEKLEPKAEQAPTVKRTETEKKPPP---IKDSKSLTAEPQKAVLPTKLEKSPK 1054
Query: 275 -------VSTEIPASEPDGPSVG---RAKGQDAPL---EFTFHVE-----ITPNVQKEQA 316
TE+ D P+ K Q L T H+ + N Q ++A
Sbjct: 1055 PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRA 1114
Query: 317 HSEEHLGRAAFPGAPGEGPEARG---PSLGEDTKEADLPE-----------PSEKQPAAA 362
S + P AP GP+A P+ K A P+ +E +
Sbjct: 1115 ISGQLGDIRKMPPAPS-GPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVIL 1173
Query: 363 PRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSD- 421
+ K + ++ MV+ + S +K K S K L L P+ S +
Sbjct: 1174 EKVKETLSMEKIPP-MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 422 -PLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
PL++ P PE + + +++ A+ K + G++
Sbjct: 1233 KPLLEEKKPT--PEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQ 1290
Query: 481 GQANATRIPAKTPPAPKTPPSSATKQVQRRP-PPAGPRSERGEP-----PKSGDRSGYSS 534
Q +P+ TP + TK ++ +P PP + ++ EP K D+S SS
Sbjct: 1291 PQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSS 1350
Query: 535 PGSPGTPGSRSRT 547
P +P S T
Sbjct: 1351 SQQPKSPQGLSDT 1363
Score = 39.3 bits (90), Expect = 0.014
Identities = 78/383 (20%), Positives = 125/383 (32%), Gaps = 73/383 (19%)
Query: 204 KGAGGKERPGSKEEVDEDRDVDES-SPQDSPPSKASPAQDGRPPQTAAR----EATSIPG 258
K + ++ K++ +D+ ++ P+ PP P G P A + ++ S P
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
P E ++P D + P ++ D P + L + P++ + S
Sbjct: 734 PPKEPSVPSEQD-------KAPVAD-DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 319 EEHLGRAAFPGAPGEGPEARGPSLGEDTKEAD---LPEPSEKQPAAAPRGKPVSRVPQLK 375
+ P P GE D +P P+ + G Q +
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ 845
Query: 376 ARMVSKSKDGTGSDDKKAKT--STRSSAKTL-KNRPCLSPKHPTPGSSDPLIQPSSP--- 429
V K ++ KKA+T S + AK + K P PT G + P Q S
Sbjct: 846 VDPVQKKEE-----PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 430 ----------AVCPEPPSSP-------------------KHVSSVTSRTGSSGAKEMKLK 460
++ P S P S++ S G G
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 461 GADGKTKIAT---PRGAAPPGQKGQA-----------NATRIPA--KTPPAPKTPPSSAT 504
GA K A P PP GQA T+ PA K P + P+
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
Query: 505 KQVQRRPPPA-GPRSERGEPPKS 526
+ +++PPP +S EP K+
Sbjct: 1021 TETEKKPPPIKDSKSLTAEPQKA 1043
Score = 37.4 bits (85), Expect = 0.054
Identities = 77/443 (17%), Positives = 148/443 (33%), Gaps = 58/443 (13%)
Query: 60 GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPS------ 113
G + + S+P + TAP+ A K ++ QP P+ A + + P
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSK-SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
Query: 114 LEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGT 173
L + H + ++ + + L +P PP + S AP+ + P++
Sbjct: 706 LVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQ-------- 756
Query: 174 GPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSP 233
P+++K P +K ++ + ++ + +P
Sbjct: 757 -----------PKMVK------------PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 234 PSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPS-VGRA 292
P K A +P Q+ + F ++ AIP P +S P+SE G V
Sbjct: 794 PLKTDSA---KPSQSFPPTGEKVSPFDSK-AIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 293 KGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPG----APGEGPEARGPSLGEDTKE 348
+ ++ P + + P+ + S G G P + P+ + S
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909
Query: 349 ADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRP 408
+ + + QP P+ ++ A + S++ + + + S +K
Sbjct: 910 GSITDAPKSQPTT-PQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ-- 966
Query: 409 CLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKI 468
P S P P + P +P V T + A++++ K T
Sbjct: 967 -------APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 469 ATPRGAAPPGQKGQANATRIPAK 491
T PP K + T P K
Sbjct: 1020 RTETEKKPPPIKDSKSLTAEPQK 1042
Score = 35.0 bits (79), Expect = 0.27
Identities = 51/216 (23%), Positives = 72/216 (33%), Gaps = 23/216 (10%)
Query: 366 KPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQ 425
KP S++P S K + RSS+ + +P P P P P
Sbjct: 2371 KPASQLPS--------GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
Query: 426 PSSPA---VCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQ 482
P P P+P PK +V S ++ D T + T G
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPL------FDAVTTLETTAVLRSNGLPVT 2476
Query: 483 ANATRIPAKTPPAPKTPPSSA--TKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
T P PP P + PS T + + PP P+ + P + + P G
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGL 2536
Query: 541 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKS 576
+ S T +L T + T P SP S KS
Sbjct: 2537 SLTSSMTLNLVTSADYKLPS----PTSPLSPHSNKS 2568
Score = 31.2 bits (69), Expect = 3.8
Identities = 54/224 (24%), Positives = 83/224 (37%), Gaps = 27/224 (12%)
Query: 380 SKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSP 439
S D D+ T +R A+ K ++ T PL + SS AV S
Sbjct: 3471 SVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTK----PLSKVSSIAVQTVAEISV 3526
Query: 440 KHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPP-APKT 498
+ T RT S A+ D K +I A KG + + A + +P+
Sbjct: 3527 QTEPVGTIRTPSIRAR------VDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQY 3580
Query: 499 PPSSATKQVQRRPPP----------AGPRSERGEPPKSGDRSGYS--SPGSPGTPGSRSR 546
+++ + ++RP P A + P + YS SP SPG +
Sbjct: 3581 LSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAF 3640
Query: 547 TP-SLPTPPTREPKKVA---VVRTPPKSPSSAKSRLQTAPVPMP 586
P P P P+KV + + PP SP +AK ++ P P
Sbjct: 3641 VPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 75.1 bits (183), Expect = 2e-13
Identities = 130/544 (23%), Positives = 179/544 (32%), Gaps = 109/544 (20%)
Query: 47 PLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA----AAQPHTEIPEGTT 102
P+ +P E GS P + P ++GAPG++ A + + P G
Sbjct: 1067 PVGSPGERGSAGTAGPIG-LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1125
Query: 103 AEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEG 162
AG +P ED G + + + G +G PGPPGL G GAP + G
Sbjct: 1126 GP-AGPAGSPG-EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ-----GPVGAPGIAGG 1178
Query: 163 PREA--TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDE 220
E Q G + EG R P GPP G + PG E E
Sbjct: 1179 DGEPGPRGQQGMFGQKGDEGARGFP--------------GPP-GPIGLQGLPGPPGEKGE 1223
Query: 221 DRDVDESSPQDSPPSKASPAQDGRP-PQTAAREATSI--------------PGFPAEGAI 265
+ DV P P + +G PQ S+ PG P E +
Sbjct: 1224 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1283
Query: 266 PLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRA 325
P + P P G D P + + G
Sbjct: 1284 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP--------------------KGNPGPV 1323
Query: 326 AFPGAPGE----GPEARGPSLGEDTKEADLPEPSEKQPA--AAPRGKPVSRVPQLKARMV 379
FPG PG GP + G+ ++ D +P P+ A P G P R P A
Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG-- 1381
Query: 380 SKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP--------GSSDPLIQPSSPAV 431
++ + G +K AK + K P + P+ P G P+ + P
Sbjct: 1382 AEGRQG----EKGAKGEAGAEGPPGKTGP-VGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436
Query: 432 C----PEPPSSPKHVSSVTSRTGSSGAKE----MKLKGADGKTKIATPRGA----APPGQ 479
P P P + + GS G K + L G G+ RG PG
Sbjct: 1437 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1496
Query: 480 KGQANATRIPAKTPP-APKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSP 538
KG IP P P PP P P GP+ +G +G + PG P
Sbjct: 1497 KGDGG---IPGPAGPLGPPGPPGL--------PGPQGPKGNKGSTGPAGQKGDSGLPGPP 1545
Query: 539 GTPG 542
G+PG
Sbjct: 1546 GSPG 1549
Score = 72.8 bits (177), Expect = 1e-12
Identities = 146/597 (24%), Positives = 190/597 (31%), Gaps = 125/597 (20%)
Query: 25 DQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGA 84
D G Y ++ +E ++ P P E+ +ET T T+ + ++G
Sbjct: 389 DLGEYDFYEYKE------YEDKPTSPPNEEFGPGVPAETD---ITETSINGHGAYGEKGQ 439
Query: 85 PGKQAAAQPH--TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGP 142
G+ A +P E P G A AGI P L+ G G + GP
Sbjct: 440 KGEPAVVEPGMLVEGPPGP-AGPAGIMGPPGLQ-------------GPTGPPGDPGDRGP 485
Query: 143 PGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLL---GDLHQE 199
PG G+PGA LP P P G + ++G + + + Q + +
Sbjct: 486 PG-----RPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 540
Query: 200 GPP----LKGAGGKER-PGSKEEVDEDRDVDESSP---QDSPPSKASPAQDGRPPQTAAR 251
GPP L G G PGS E D P Q P P + GRP R
Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600
Query: 252 EATSIPGFPAE----GAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEI 307
PG + G LP D + P P P +G+D EI
Sbjct: 601 GMPGEPGAKGDRGFDGLPGLPGDKGHR-GERGPQGPPGPPGDDGMRGEDG--------EI 651
Query: 308 TPNVQKEQAHSEEHLGRAAFPGAPGE----------GPEARGPSLGEDTKEADL--PEPS 355
P +A LG PGAPG+ GP+ GE P P
Sbjct: 652 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 711
Query: 356 EKQPAAAPRGKPVSRVPQLKARMVS-KSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKH 414
P G P + PQ K + DG K S A L P
Sbjct: 712 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA--------LGP-- 761
Query: 415 PTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK----------EMKLKGADG 464
PG P+ P P K V GS G K +M LKG G
Sbjct: 762 --PGPQGPIGYPG--------PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 811
Query: 465 KTKIATPRGA-APPGQKGQANATRIPAKTPPA--------------------------PK 497
+ PRG P G KG+A T P + A P
Sbjct: 812 EVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 871
Query: 498 TPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
P ++ K + GPR +RG G R G PG G+ S P PP
Sbjct: 872 FPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT-SGGDGPPGPP 927
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/554 (24%), Positives = 185/554 (33%), Gaps = 103/554 (18%)
Query: 47 PLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEA 106
P TP G +PG D P P + G PG+Q P +G +
Sbjct: 668 PRGTPGAPG--QPGMAGVDGPPGPKGN--MGPQGEPGPPGQQGNPGP-----QGLPGPQG 718
Query: 107 GIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREA 166
IG G + + G G PG PG Q SG GA L P GP+
Sbjct: 719 PIGPP--------GEKGPQGKPGLAGLPGADGPPGHPGKEGQ--SGEKGA-LGPPGPQGP 767
Query: 167 TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEG-PPLKGAGGKERPGSKEEVDEDRDVD 225
P G + +G R LK G+ ++G P KG G + G + EV +
Sbjct: 768 IGYPGPRGVKGADGVRG----LKGSK-GEKGEDGFPGFKGDMGLK--GDRGEVGQIGPRG 820
Query: 226 ESSPQDSPPSKASPAQDGRPP-QTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP 284
E P+ P +A P D P Q + +PG P P K ST P
Sbjct: 821 EDGPE-GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP-----KGSTGFPGF-- 872
Query: 285 DGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGE 344
P KG V P + ++ + R A P P +G S G+
Sbjct: 873 --PGANGEKGARG-------VAGKPGPRGQRGPTGPRGSRGA--RGPTGKPGPKGTSGGD 921
Query: 345 DTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT-GSDDKKAKTSTRSSAKT 403
P P ++ P+G PV P K KDG G ++ +T +
Sbjct: 922 GP-----PGPPGERGPQGPQG-PVG-FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 974
Query: 404 LKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSS-----------------PKHVSSVT 446
+ P+ PT G + P+ + P P PP P+ +S
Sbjct: 975 PGPGGVVGPQGPT-GETGPIGERGHPGP-PGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1032
Query: 447 SRTGSSGAK-EMKLKGADGKTKI-------ATPRGAAPPGQKGQANATRIPAKTP--PAP 496
G G E L GA G + P PG++G A T P P P P
Sbjct: 1033 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG-TAGPIGLPGRPGP 1091
Query: 497 KTPPSSATKQ----------------VQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
+ PP A ++ VQ GP G P + GD+ PG G+
Sbjct: 1092 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1151
Query: 541 PGSRSRTPSLPTPP 554
G + P PP
Sbjct: 1152 KGDKGEN-GPPGPP 1164
Score = 55.8 bits (133), Expect = 1e-07
Identities = 126/508 (24%), Positives = 167/508 (32%), Gaps = 84/508 (16%)
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP 157
P+GT+ GD P G Q P+ G V G PGPPG G+PG P
Sbjct: 914 PKGTSG-----GDGPPGPPGERG--PQGPQ-GPVGFPGPKGPPGPPG-----KDGLPGHP 960
Query: 158 LLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQL--LGDLHQEGPP-------LKGAGG 208
G R T TGP GG P+ + +G+ GPP L GA G
Sbjct: 961 ----GQRGETGFQGKTGPPGP-GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG 1015
Query: 209 KERPGSKEEVDEDRDVDESSPQDSPPS-KASPAQDGRPPQTAAREATSIPGFPAEGAIPL 267
KE G+K D S +D P + P + G P A+ A + G P
Sbjct: 1016 KE--GAKG----DPGPQGISGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG 1066
Query: 268 PVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAF 327
PV + + A P GR Q P P +K + G A
Sbjct: 1067 PVGSPGERGSAGTAGPIGLP--GRPGPQGPP---------GPAGEKGAPGEKGPQGPAGR 1115
Query: 328 PGAPGE----GPEARGPSLGEDTKEADLPEPSEKQPAA-----APRGKPVSRVPQLKARM 378
G G GP S GED + ++ EP +K P G P + P + A
Sbjct: 1116 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP-VGAPG 1174
Query: 379 VSKSKDGTGSDDKKAKTSTRSSAKT-----------LKNRPCLSPKHPTPGSSDPLIQPS 427
++ G ++ + L+ P + G P+ P
Sbjct: 1175 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1234
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKE-MKLKGADGKTKIATPRGAA----PPGQKGQ 482
P P P P GS G+ + KG G+ P G A P G++G+
Sbjct: 1235 PPG--PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1292
Query: 483 ANATRIP-AKTPPAPKTPPSSATKQ-------VQRRPPPAGPRSERGEPPKSGDRSGYSS 534
P A PP K PP + P P G G+ GD+
Sbjct: 1293 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1352
Query: 535 PGSPGTPGSRSRTPSLPTPPTREPKKVA 562
PG PG PG P R P A
Sbjct: 1353 PGQPGPPGPSGEAGPPGPPGKRGPPGAA 1380
Score = 49.7 bits (117), Expect = 1e-05
Identities = 112/501 (22%), Positives = 154/501 (30%), Gaps = 113/501 (22%)
Query: 81 DEGAPGKQAAAQPHTEI-PEGTTAEEAGIGDT-------PSLEDEAAGHVTQEPESGKVV 132
+ G GK P + P+G T E IG+ P E G +E G
Sbjct: 965 ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1024
Query: 133 QEGFLREPGPPGL----SHQLMSGMPGAPLL-----PEGPREATRQPSGTGPEDTEG--- 180
+G + GP GL + + G GAP L P+GP P G T G
Sbjct: 1025 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1084
Query: 181 --GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVD-ESSPQDSPPSKA 237
GR P+ G ++G P G G + P ++ V + + P SP
Sbjct: 1085 LPGRPGPQGPP----GPAGEKGAP--GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1138
Query: 238 SPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDA 297
+ G P Q ++ G P + PV P + G+
Sbjct: 1139 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG---------------APGIAGGDGEPG 1183
Query: 298 PLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEPSE 356
P Q+ + G FPG PG G + GE + D+
Sbjct: 1184 P-----------RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP--- 1229
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT 416
P G P R PQ G+D + + S + +
Sbjct: 1230 ----MGPPGPPGPRGPQ----------GPNGADGPQGPPGSVGSVGGVGEKG-------E 1268
Query: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK-EMKLKGADGKTKIATPRGA- 474
PG + P PP G G K E KG G A P GA
Sbjct: 1269 PGEAGN----------PGPPGE----------AGVGGPKGERGEKGEAGPPGAAGPPGAK 1308
Query: 475 APPGQKG-QANATRIPAKTPPAPKTPPSSATKQV----------QRRPPPAGPRSERGEP 523
PPG G + N + P P P A + +P P GP E G P
Sbjct: 1309 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1368
Query: 524 PKSGDRSGYSSPGSPGTPGSR 544
G R + G+ G G +
Sbjct: 1369 GPPGKRGPPGAAGAEGRQGEK 1389
Score = 46.6 bits (109), Expect = 9e-05
Identities = 124/516 (24%), Positives = 162/516 (31%), Gaps = 112/516 (21%)
Query: 99 EGTTAEEAGIG----DTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL-SHQLMSGM 153
+G E IG D P AG SG+ ++G L PG PG Q G
Sbjct: 807 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 866
Query: 154 PGAPLLP-----EGPREATRQPSG------TGPEDTEGGRHAPELLKHQLLGDLHQEGPP 202
G P P +G R +P TGP + G R G + GP
Sbjct: 867 TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR-----------GPTGKPGP- 914
Query: 203 LKGAGGKERP----GSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPG 258
KG G + P G + V P+ P P +DG P R T G
Sbjct: 915 -KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP---GPPGKDGLPGHPGQRGET---G 967
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
F + P P + P GP+ G+ P+
Sbjct: 968 FQGKTGPPGPGGVVG----------PQGPT-----GETGPI------------------- 993
Query: 319 EEHLGRAAFPGAPGEGPEARGP-SLGEDTKEADLPEP---SEKQPAAAPRGKPVSR-VPQ 373
G PG PG E P + G++ + D P P S K A RG P R +P
Sbjct: 994 ----GERGHPGPPGPPGEQGLPGAAGKEGAKGD-PGPQGISGKDGPAGLRGFPGERGLPG 1048
Query: 374 LKARMVSKSKDGT-GSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP-GSSDPLIQPSSPAV 431
+ K +G G R SA T P P P P G P + +P
Sbjct: 1049 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG--PIGLPGRPGPQGPPGPAGEKGAPGE 1106
Query: 432 C-PEPPSSPKHVSSVTSRTGSSGAK-------------EMKLKGADGKTKIATPRGAAPP 477
P+ P+ V G +G E KG+ G P G PP
Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG--PP 1164
Query: 478 GQKGQANATRIPAKT-PPAPKTPPS-------SATKQVQRRPPPAGPRSERGEPPKSGDR 529
G +G A I P P+ + P P G + G P + G+
Sbjct: 1165 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1224
Query: 530 SGYSSPGSPGTPGSRS-RTPSLPTPPTREPKKVAVV 564
G PG PG R + P+ P P V V
Sbjct: 1225 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1260
Score = 40.0 bits (92), Expect = 0.008
Identities = 124/591 (20%), Positives = 180/591 (30%), Gaps = 103/591 (17%)
Query: 21 GDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSE----TSDAKSTPTAEDVT 76
GD K Y H + D+ A K + Q P D ++ + T KS ++ T
Sbjct: 227 GDPKAAYDYCEHYSPDCDSSAP-KAAQAQEPQIDEKKKSNFKKKMRTVATKSKEKSKKFT 285
Query: 77 APLVDEGAPGKQAAAQPHTEIPEGTTA------EEAGIGDTPSLEDEAAGHV--TQEPES 128
P ++ + K+ + Q + G A +E G S + EA HV T EP
Sbjct: 286 PPKSEKFSSKKKKSYQASAKAKLGVKANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNP 345
Query: 129 -GKVVQEGFL--------REPGPPGLSHQLMSGMPGAPLLPEGP---------REATRQP 170
++ E +L R+ L + LL +G +E +P
Sbjct: 346 VEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKP 405
Query: 171 SGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQ 230
T P + E G P + + G G G K + E V+
Sbjct: 406 --TSPPNEEFGPGVP--------AETDITETSINGHGAY---GEKGQKGEPAVVEPGMLV 452
Query: 231 DSPPSKASPA----------QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIP 280
+ PP A PA G P R PG P +P P + +
Sbjct: 453 EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG 512
Query: 281 ASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARG 339
GP++ + Q+ QA + R A G PG G R
Sbjct: 513 GDGSKGPTI--------------------SAQEAQAQAILQQARIALRGPPGPMGLTGRP 552
Query: 340 PSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRS 399
+G E + P PRG V P + + + G
Sbjct: 553 GPVGGPGSSGAKGESGDPGPQG-PRG--VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 609
Query: 400 SAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKL 459
+ P L G P + P P + G G + L
Sbjct: 610 GDRGFDGLPGLPGDKGHRGERGP-----------QGPPGPPGDDGMRGEDGEIGPRG--L 656
Query: 460 KGADGKTKIATPRGA-APPGQKGQANATRIPA-KTPPAPKTPPSSATKQ----VQRRPPP 513
G G + PRG PGQ G A P K P+ P +Q Q P P
Sbjct: 657 PGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP 716
Query: 514 AGP------RSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 558
GP + +G+P +G PG PG G +L P + P
Sbjct: 717 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP 767
Score = 34.7 bits (78), Expect = 0.35
Identities = 43/152 (28%), Positives = 50/152 (32%), Gaps = 22/152 (14%)
Query: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP 476
PGSS + P P P+ V TG G + GADG G
Sbjct: 558 PGSSGAKGESGDPG-----PQGPRGVQGPPGPTGKPGKRGRP--GADG--------GRGM 602
Query: 477 PGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPG 536
PG+ G A R P P + Q P P G RGE + G R G
Sbjct: 603 PGEPG-AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 655
Query: 537 SPGTPGSRSRTPSLPTPPTREPKKVAVVRTPP 568
PG G R TP +A V PP
Sbjct: 656 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 687
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 75.1 bits (183), Expect = 2e-13
Identities = 130/544 (23%), Positives = 179/544 (32%), Gaps = 109/544 (20%)
Query: 47 PLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA----AAQPHTEIPEGTT 102
P+ +P E GS P + P ++GAPG++ A + + P G
Sbjct: 1016 PVGSPGERGSAGTAGPIG-LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1074
Query: 103 AEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEG 162
AG +P ED G + + + G +G PGPPGL G GAP + G
Sbjct: 1075 GP-AGPAGSPG-EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ-----GPVGAPGIAGG 1127
Query: 163 PREA--TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDE 220
E Q G + EG R P GPP G + PG E E
Sbjct: 1128 DGEPGPRGQQGMFGQKGDEGARGFP--------------GPP-GPIGLQGLPGPPGEKGE 1172
Query: 221 DRDVDESSPQDSPPSKASPAQDGRP-PQTAAREATSI--------------PGFPAEGAI 265
+ DV P P + +G PQ S+ PG P E +
Sbjct: 1173 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1232
Query: 266 PLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRA 325
P + P P G D P + + G
Sbjct: 1233 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP--------------------KGNPGPV 1272
Query: 326 AFPGAPGE----GPEARGPSLGEDTKEADLPEPSEKQPA--AAPRGKPVSRVPQLKARMV 379
FPG PG GP + G+ ++ D +P P+ A P G P R P A
Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG-- 1330
Query: 380 SKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP--------GSSDPLIQPSSPAV 431
++ + G +K AK + K P + P+ P G P+ + P
Sbjct: 1331 AEGRQG----EKGAKGEAGAEGPPGKTGP-VGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385
Query: 432 C----PEPPSSPKHVSSVTSRTGSSGAKE----MKLKGADGKTKIATPRGA----APPGQ 479
P P P + + GS G K + L G G+ RG PG
Sbjct: 1386 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1445
Query: 480 KGQANATRIPAKTPP-APKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSP 538
KG IP P P PP P P GP+ +G +G + PG P
Sbjct: 1446 KGDGG---IPGPAGPLGPPGPPGL--------PGPQGPKGNKGSTGPAGQKGDSGLPGPP 1494
Query: 539 GTPG 542
G+PG
Sbjct: 1495 GSPG 1498
Score = 72.8 bits (177), Expect = 1e-12
Identities = 146/597 (24%), Positives = 190/597 (31%), Gaps = 125/597 (20%)
Query: 25 DQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGA 84
D G Y ++ +E ++ P P E+ +ET T T+ + ++G
Sbjct: 338 DLGEYDFYEYKE------YEDKPTSPPNEEFGPGVPAETD---ITETSINGHGAYGEKGQ 388
Query: 85 PGKQAAAQPH--TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGP 142
G+ A +P E P G A AGI P L+ G G + GP
Sbjct: 389 KGEPAVVEPGMLVEGPPGP-AGPAGIMGPPGLQ-------------GPTGPPGDPGDRGP 434
Query: 143 PGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLL---GDLHQE 199
PG G+PGA LP P P G + ++G + + + Q + +
Sbjct: 435 PG-----RPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 489
Query: 200 GPP----LKGAGGKER-PGSKEEVDEDRDVDESSP---QDSPPSKASPAQDGRPPQTAAR 251
GPP L G G PGS E D P Q P P + GRP R
Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549
Query: 252 EATSIPGFPAE----GAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEI 307
PG + G LP D + P P P +G+D EI
Sbjct: 550 GMPGEPGAKGDRGFDGLPGLPGDKGHR-GERGPQGPPGPPGDDGMRGEDG--------EI 600
Query: 308 TPNVQKEQAHSEEHLGRAAFPGAPGE----------GPEARGPSLGEDTKEADL--PEPS 355
P +A LG PGAPG+ GP+ GE P P
Sbjct: 601 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 660
Query: 356 EKQPAAAPRGKPVSRVPQLKARMVS-KSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKH 414
P G P + PQ K + DG K S A L P
Sbjct: 661 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA--------LGP-- 710
Query: 415 PTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK----------EMKLKGADG 464
PG P+ P P K V GS G K +M LKG G
Sbjct: 711 --PGPQGPIGYPG--------PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 760
Query: 465 KTKIATPRGA-APPGQKGQANATRIPAKTPPA--------------------------PK 497
+ PRG P G KG+A T P + A P
Sbjct: 761 EVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 820
Query: 498 TPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
P ++ K + GPR +RG G R G PG G+ S P PP
Sbjct: 821 FPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT-SGGDGPPGPP 876
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/554 (24%), Positives = 185/554 (33%), Gaps = 103/554 (18%)
Query: 47 PLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEA 106
P TP G +PG D P P + G PG+Q P +G +
Sbjct: 617 PRGTPGAPG--QPGMAGVDGPPGPKGN--MGPQGEPGPPGQQGNPGP-----QGLPGPQG 667
Query: 107 GIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREA 166
IG G + + G G PG PG Q SG GA L P GP+
Sbjct: 668 PIGPP--------GEKGPQGKPGLAGLPGADGPPGHPGKEGQ--SGEKGA-LGPPGPQGP 716
Query: 167 TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEG-PPLKGAGGKERPGSKEEVDEDRDVD 225
P G + +G R LK G+ ++G P KG G + G + EV +
Sbjct: 717 IGYPGPRGVKGADGVRG----LKGSK-GEKGEDGFPGFKGDMGLK--GDRGEVGQIGPRG 769
Query: 226 ESSPQDSPPSKASPAQDGRPP-QTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP 284
E P+ P +A P D P Q + +PG P P K ST P
Sbjct: 770 EDGPE-GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP-----KGSTGFPGF-- 821
Query: 285 DGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGE 344
P KG V P + ++ + R A P P +G S G+
Sbjct: 822 --PGANGEKGARG-------VAGKPGPRGQRGPTGPRGSRGA--RGPTGKPGPKGTSGGD 870
Query: 345 DTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT-GSDDKKAKTSTRSSAKT 403
P P ++ P+G PV P K KDG G ++ +T +
Sbjct: 871 GP-----PGPPGERGPQGPQG-PVG-FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 923
Query: 404 LKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSS-----------------PKHVSSVT 446
+ P+ PT G + P+ + P P PP P+ +S
Sbjct: 924 PGPGGVVGPQGPT-GETGPIGERGHPGP-PGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 981
Query: 447 SRTGSSGAK-EMKLKGADGKTKI-------ATPRGAAPPGQKGQANATRIPAKTP--PAP 496
G G E L GA G + P PG++G A T P P P P
Sbjct: 982 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG-TAGPIGLPGRPGP 1040
Query: 497 KTPPSSATKQ----------------VQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
+ PP A ++ VQ GP G P + GD+ PG G+
Sbjct: 1041 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1100
Query: 541 PGSRSRTPSLPTPP 554
G + P PP
Sbjct: 1101 KGDKGEN-GPPGPP 1113
Score = 55.8 bits (133), Expect = 1e-07
Identities = 126/508 (24%), Positives = 167/508 (32%), Gaps = 84/508 (16%)
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP 157
P+GT+ GD P G Q P+ G V G PGPPG G+PG P
Sbjct: 863 PKGTSG-----GDGPPGPPGERG--PQGPQ-GPVGFPGPKGPPGPPG-----KDGLPGHP 909
Query: 158 LLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQL--LGDLHQEGPP-------LKGAGG 208
G R T TGP GG P+ + +G+ GPP L GA G
Sbjct: 910 ----GQRGETGFQGKTGPPGP-GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG 964
Query: 209 KERPGSKEEVDEDRDVDESSPQDSPPS-KASPAQDGRPPQTAAREATSIPGFPAEGAIPL 267
KE G+K D S +D P + P + G P A+ A + G P
Sbjct: 965 KE--GAKG----DPGPQGISGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG 1015
Query: 268 PVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAF 327
PV + + A P GR Q P P +K + G A
Sbjct: 1016 PVGSPGERGSAGTAGPIGLP--GRPGPQGPP---------GPAGEKGAPGEKGPQGPAGR 1064
Query: 328 PGAPGE----GPEARGPSLGEDTKEADLPEPSEKQPAA-----APRGKPVSRVPQLKARM 378
G G GP S GED + ++ EP +K P G P + P + A
Sbjct: 1065 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP-VGAPG 1123
Query: 379 VSKSKDGTGSDDKKAKTSTRSSAKT-----------LKNRPCLSPKHPTPGSSDPLIQPS 427
++ G ++ + L+ P + G P+ P
Sbjct: 1124 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1183
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKE-MKLKGADGKTKIATPRGAA----PPGQKGQ 482
P P P P GS G+ + KG G+ P G A P G++G+
Sbjct: 1184 PPG--PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241
Query: 483 ANATRIP-AKTPPAPKTPPSSATKQ-------VQRRPPPAGPRSERGEPPKSGDRSGYSS 534
P A PP K PP + P P G G+ GD+
Sbjct: 1242 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1301
Query: 535 PGSPGTPGSRSRTPSLPTPPTREPKKVA 562
PG PG PG P R P A
Sbjct: 1302 PGQPGPPGPSGEAGPPGPPGKRGPPGAA 1329
Score = 49.7 bits (117), Expect = 1e-05
Identities = 112/501 (22%), Positives = 154/501 (30%), Gaps = 113/501 (22%)
Query: 81 DEGAPGKQAAAQPHTEI-PEGTTAEEAGIGDT-------PSLEDEAAGHVTQEPESGKVV 132
+ G GK P + P+G T E IG+ P E G +E G
Sbjct: 914 ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 973
Query: 133 QEGFLREPGPPGL----SHQLMSGMPGAPLL-----PEGPREATRQPSGTGPEDTEG--- 180
+G + GP GL + + G GAP L P+GP P G T G
Sbjct: 974 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1033
Query: 181 --GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVD-ESSPQDSPPSKA 237
GR P+ G ++G P G G + P ++ V + + P SP
Sbjct: 1034 LPGRPGPQGPP----GPAGEKGAP--GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1087
Query: 238 SPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDA 297
+ G P Q ++ G P + PV P + G+
Sbjct: 1088 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG---------------APGIAGGDGEPG 1132
Query: 298 PLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEPSE 356
P Q+ + G FPG PG G + GE + D+
Sbjct: 1133 P-----------RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP--- 1178
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT 416
P G P R PQ G+D + + S + +
Sbjct: 1179 ----MGPPGPPGPRGPQ----------GPNGADGPQGPPGSVGSVGGVGEKG-------E 1217
Query: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK-EMKLKGADGKTKIATPRGA- 474
PG + P PP G G K E KG G A P GA
Sbjct: 1218 PGEAGN----------PGPPGE----------AGVGGPKGERGEKGEAGPPGAAGPPGAK 1257
Query: 475 APPGQKG-QANATRIPAKTPPAPKTPPSSATKQV----------QRRPPPAGPRSERGEP 523
PPG G + N + P P P A + +P P GP E G P
Sbjct: 1258 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1317
Query: 524 PKSGDRSGYSSPGSPGTPGSR 544
G R + G+ G G +
Sbjct: 1318 GPPGKRGPPGAAGAEGRQGEK 1338
Score = 46.6 bits (109), Expect = 9e-05
Identities = 124/516 (24%), Positives = 162/516 (31%), Gaps = 112/516 (21%)
Query: 99 EGTTAEEAGIG----DTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL-SHQLMSGM 153
+G E IG D P AG SG+ ++G L PG PG Q G
Sbjct: 756 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 815
Query: 154 PGAPLLP-----EGPREATRQPSG------TGPEDTEGGRHAPELLKHQLLGDLHQEGPP 202
G P P +G R +P TGP + G R G + GP
Sbjct: 816 TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR-----------GPTGKPGP- 863
Query: 203 LKGAGGKERP----GSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPG 258
KG G + P G + V P+ P P +DG P R T G
Sbjct: 864 -KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP---GPPGKDGLPGHPGQRGET---G 916
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
F + P P + P GP+ G+ P+
Sbjct: 917 FQGKTGPPGPGGVVG----------PQGPT-----GETGPI------------------- 942
Query: 319 EEHLGRAAFPGAPGEGPEARGP-SLGEDTKEADLPEP---SEKQPAAAPRGKPVSR-VPQ 373
G PG PG E P + G++ + D P P S K A RG P R +P
Sbjct: 943 ----GERGHPGPPGPPGEQGLPGAAGKEGAKGD-PGPQGISGKDGPAGLRGFPGERGLPG 997
Query: 374 LKARMVSKSKDGT-GSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP-GSSDPLIQPSSPAV 431
+ K +G G R SA T P P P P G P + +P
Sbjct: 998 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG--PIGLPGRPGPQGPPGPAGEKGAPGE 1055
Query: 432 C-PEPPSSPKHVSSVTSRTGSSGAK-------------EMKLKGADGKTKIATPRGAAPP 477
P+ P+ V G +G E KG+ G P G PP
Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG--PP 1113
Query: 478 GQKGQANATRIPAKT-PPAPKTPPS-------SATKQVQRRPPPAGPRSERGEPPKSGDR 529
G +G A I P P+ + P P G + G P + G+
Sbjct: 1114 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1173
Query: 530 SGYSSPGSPGTPGSRS-RTPSLPTPPTREPKKVAVV 564
G PG PG R + P+ P P V V
Sbjct: 1174 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1209
Score = 39.7 bits (91), Expect = 0.011
Identities = 78/369 (21%), Positives = 107/369 (28%), Gaps = 59/369 (15%)
Query: 213 GSKEEVDEDRDVDESSPQDSPPSKASPA----------QDGRPPQTAAREATSIPGFPAE 262
G K + E V+ + PP A PA G P R PG P
Sbjct: 384 GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGA 443
Query: 263 GAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHL 322
+P P + + GP++ + Q+ QA +
Sbjct: 444 DGLPGPPGTMLMLPFRYGGDGSKGPTI--------------------SAQEAQAQAILQQ 483
Query: 323 GRAAFPGAPGE-GPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSK 381
R A G PG G R +G E + P PRG V P + +
Sbjct: 484 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG-PRG--VQGPPGPTGKPGKR 540
Query: 382 SKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKH 441
+ G + P L G P + P P
Sbjct: 541 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP-----------QGPPGPPG 589
Query: 442 VSSVTSRTGSSGAKEMKLKGADGKTKIATPRGA-APPGQKGQANATRIPA-KTPPAPKTP 499
+ G G + L G G + PRG PGQ G A P K P+
Sbjct: 590 DDGMRGEDGEIGPRG--LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 647
Query: 500 PSSATKQ----VQRRPPPAGP------RSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPS 549
P +Q Q P P GP + +G+P +G PG PG G +
Sbjct: 648 PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 707
Query: 550 LPTPPTREP 558
L P + P
Sbjct: 708 LGPPGPQGP 716
Score = 34.7 bits (78), Expect = 0.35
Identities = 43/152 (28%), Positives = 50/152 (32%), Gaps = 22/152 (14%)
Query: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP 476
PGSS + P P P+ V TG G + GADG G
Sbjct: 507 PGSSGAKGESGDPG-----PQGPRGVQGPPGPTGKPGKRGRP--GADG--------GRGM 551
Query: 477 PGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPG 536
PG+ G A R P P + Q P P G RGE + G R G
Sbjct: 552 PGEPG-AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 604
Query: 537 SPGTPGSRSRTPSLPTPPTREPKKVAVVRTPP 568
PG G R TP +A V PP
Sbjct: 605 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 636
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 75.1 bits (183), Expect = 2e-13
Identities = 130/544 (23%), Positives = 179/544 (32%), Gaps = 109/544 (20%)
Query: 47 PLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQA----AAQPHTEIPEGTT 102
P+ +P E GS P + P ++GAPG++ A + + P G
Sbjct: 1055 PVGSPGERGSAGTAGPIG-LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP 1113
Query: 103 AEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEG 162
AG +P ED G + + + G +G PGPPGL G GAP + G
Sbjct: 1114 GP-AGPAGSPG-EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ-----GPVGAPGIAGG 1166
Query: 163 PREA--TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDE 220
E Q G + EG R P GPP G + PG E E
Sbjct: 1167 DGEPGPRGQQGMFGQKGDEGARGFP--------------GPP-GPIGLQGLPGPPGEKGE 1211
Query: 221 DRDVDESSPQDSPPSKASPAQDGRP-PQTAAREATSI--------------PGFPAEGAI 265
+ DV P P + +G PQ S+ PG P E +
Sbjct: 1212 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1271
Query: 266 PLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRA 325
P + P P G D P + + G
Sbjct: 1272 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP--------------------KGNPGPV 1311
Query: 326 AFPGAPGE----GPEARGPSLGEDTKEADLPEPSEKQPA--AAPRGKPVSRVPQLKARMV 379
FPG PG GP + G+ ++ D +P P+ A P G P R P A
Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG-- 1369
Query: 380 SKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP--------GSSDPLIQPSSPAV 431
++ + G +K AK + K P + P+ P G P+ + P
Sbjct: 1370 AEGRQG----EKGAKGEAGAEGPPGKTGP-VGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424
Query: 432 C----PEPPSSPKHVSSVTSRTGSSGAKE----MKLKGADGKTKIATPRGA----APPGQ 479
P P P + + GS G K + L G G+ RG PG
Sbjct: 1425 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1484
Query: 480 KGQANATRIPAKTPP-APKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSP 538
KG IP P P PP P P GP+ +G +G + PG P
Sbjct: 1485 KGDGG---IPGPAGPLGPPGPPGL--------PGPQGPKGNKGSTGPAGQKGDSGLPGPP 1533
Query: 539 GTPG 542
G+PG
Sbjct: 1534 GSPG 1537
Score = 72.8 bits (177), Expect = 1e-12
Identities = 146/597 (24%), Positives = 190/597 (31%), Gaps = 125/597 (20%)
Query: 25 DQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGA 84
D G Y ++ +E ++ P P E+ +ET T T+ + ++G
Sbjct: 377 DLGEYDFYEYKE------YEDKPTSPPNEEFGPGVPAETD---ITETSINGHGAYGEKGQ 427
Query: 85 PGKQAAAQPH--TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGP 142
G+ A +P E P G A AGI P L+ G G + GP
Sbjct: 428 KGEPAVVEPGMLVEGPPGP-AGPAGIMGPPGLQ-------------GPTGPPGDPGDRGP 473
Query: 143 PGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLL---GDLHQE 199
PG G+PGA LP P P G + ++G + + + Q + +
Sbjct: 474 PG-----RPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 528
Query: 200 GPP----LKGAGGKER-PGSKEEVDEDRDVDESSP---QDSPPSKASPAQDGRPPQTAAR 251
GPP L G G PGS E D P Q P P + GRP R
Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588
Query: 252 EATSIPGFPAE----GAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEI 307
PG + G LP D + P P P +G+D EI
Sbjct: 589 GMPGEPGAKGDRGFDGLPGLPGDKGHR-GERGPQGPPGPPGDDGMRGEDG--------EI 639
Query: 308 TPNVQKEQAHSEEHLGRAAFPGAPGE----------GPEARGPSLGEDTKEADL--PEPS 355
P +A LG PGAPG+ GP+ GE P P
Sbjct: 640 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 699
Query: 356 EKQPAAAPRGKPVSRVPQLKARMVS-KSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKH 414
P G P + PQ K + DG K S A L P
Sbjct: 700 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA--------LGP-- 749
Query: 415 PTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK----------EMKLKGADG 464
PG P+ P P K V GS G K +M LKG G
Sbjct: 750 --PGPQGPIGYPG--------PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG 799
Query: 465 KTKIATPRGA-APPGQKGQANATRIPAKTPPA--------------------------PK 497
+ PRG P G KG+A T P + A P
Sbjct: 800 EVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 859
Query: 498 TPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
P ++ K + GPR +RG G R G PG G+ S P PP
Sbjct: 860 FPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT-SGGDGPPGPP 915
Score = 56.6 bits (135), Expect = 9e-08
Identities = 135/554 (24%), Positives = 185/554 (33%), Gaps = 103/554 (18%)
Query: 47 PLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEA 106
P TP G +PG D P P + G PG+Q P +G +
Sbjct: 656 PRGTPGAPG--QPGMAGVDGPPGPKGN--MGPQGEPGPPGQQGNPGP-----QGLPGPQG 706
Query: 107 GIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREA 166
IG G + + G G PG PG Q SG GA L P GP+
Sbjct: 707 PIGPP--------GEKGPQGKPGLAGLPGADGPPGHPGKEGQ--SGEKGA-LGPPGPQGP 755
Query: 167 TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEG-PPLKGAGGKERPGSKEEVDEDRDVD 225
P G + +G R LK G+ ++G P KG G + G + EV +
Sbjct: 756 IGYPGPRGVKGADGVRG----LKGSK-GEKGEDGFPGFKGDMGLK--GDRGEVGQIGPRG 808
Query: 226 ESSPQDSPPSKASPAQDGRPP-QTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP 284
E P+ P +A P D P Q + +PG P P K ST P
Sbjct: 809 EDGPE-GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP-----KGSTGFPGF-- 860
Query: 285 DGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGE 344
P KG V P + ++ + R A P P +G S G+
Sbjct: 861 --PGANGEKGARG-------VAGKPGPRGQRGPTGPRGSRGA--RGPTGKPGPKGTSGGD 909
Query: 345 DTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT-GSDDKKAKTSTRSSAKT 403
P P ++ P+G PV P K KDG G ++ +T +
Sbjct: 910 GP-----PGPPGERGPQGPQG-PVG-FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 962
Query: 404 LKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSS-----------------PKHVSSVT 446
+ P+ PT G + P+ + P P PP P+ +S
Sbjct: 963 PGPGGVVGPQGPT-GETGPIGERGHPGP-PGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1020
Query: 447 SRTGSSGAK-EMKLKGADGKTKI-------ATPRGAAPPGQKGQANATRIPAKTP--PAP 496
G G E L GA G + P PG++G A T P P P P
Sbjct: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG-TAGPIGLPGRPGP 1079
Query: 497 KTPPSSATKQ----------------VQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
+ PP A ++ VQ GP G P + GD+ PG G+
Sbjct: 1080 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1139
Query: 541 PGSRSRTPSLPTPP 554
G + P PP
Sbjct: 1140 KGDKGEN-GPPGPP 1152
Score = 55.8 bits (133), Expect = 1e-07
Identities = 126/508 (24%), Positives = 167/508 (32%), Gaps = 84/508 (16%)
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP 157
P+GT+ GD P G Q P+ G V G PGPPG G+PG P
Sbjct: 902 PKGTSG-----GDGPPGPPGERG--PQGPQ-GPVGFPGPKGPPGPPG-----KDGLPGHP 948
Query: 158 LLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQL--LGDLHQEGPP-------LKGAGG 208
G R T TGP GG P+ + +G+ GPP L GA G
Sbjct: 949 ----GQRGETGFQGKTGPPGP-GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG 1003
Query: 209 KERPGSKEEVDEDRDVDESSPQDSPPS-KASPAQDGRPPQTAAREATSIPGFPAEGAIPL 267
KE G+K D S +D P + P + G P A+ A + G P
Sbjct: 1004 KE--GAKG----DPGPQGISGKDGPAGLRGFPGERGLP---GAQGAPGLKGGEGPQGPPG 1054
Query: 268 PVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAF 327
PV + + A P GR Q P P +K + G A
Sbjct: 1055 PVGSPGERGSAGTAGPIGLP--GRPGPQGPP---------GPAGEKGAPGEKGPQGPAGR 1103
Query: 328 PGAPGE----GPEARGPSLGEDTKEADLPEPSEKQPAA-----APRGKPVSRVPQLKARM 378
G G GP S GED + ++ EP +K P G P + P + A
Sbjct: 1104 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP-VGAPG 1162
Query: 379 VSKSKDGTGSDDKKAKTSTRSSAKT-----------LKNRPCLSPKHPTPGSSDPLIQPS 427
++ G ++ + L+ P + G P+ P
Sbjct: 1163 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1222
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKE-MKLKGADGKTKIATPRGAA----PPGQKGQ 482
P P P P GS G+ + KG G+ P G A P G++G+
Sbjct: 1223 PPG--PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280
Query: 483 ANATRIP-AKTPPAPKTPPSSATKQ-------VQRRPPPAGPRSERGEPPKSGDRSGYSS 534
P A PP K PP + P P G G+ GD+
Sbjct: 1281 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1340
Query: 535 PGSPGTPGSRSRTPSLPTPPTREPKKVA 562
PG PG PG P R P A
Sbjct: 1341 PGQPGPPGPSGEAGPPGPPGKRGPPGAA 1368
Score = 49.7 bits (117), Expect = 1e-05
Identities = 112/501 (22%), Positives = 154/501 (30%), Gaps = 113/501 (22%)
Query: 81 DEGAPGKQAAAQPHTEI-PEGTTAEEAGIGDT-------PSLEDEAAGHVTQEPESGKVV 132
+ G GK P + P+G T E IG+ P E G +E G
Sbjct: 953 ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1012
Query: 133 QEGFLREPGPPGL----SHQLMSGMPGAPLL-----PEGPREATRQPSGTGPEDTEG--- 180
+G + GP GL + + G GAP L P+GP P G T G
Sbjct: 1013 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1072
Query: 181 --GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVD-ESSPQDSPPSKA 237
GR P+ G ++G P G G + P ++ V + + P SP
Sbjct: 1073 LPGRPGPQGPP----GPAGEKGAP--GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1126
Query: 238 SPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDA 297
+ G P Q ++ G P + PV P + G+
Sbjct: 1127 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG---------------APGIAGGDGEPG 1171
Query: 298 PLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEPSE 356
P Q+ + G FPG PG G + GE + D+
Sbjct: 1172 P-----------RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP--- 1217
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT 416
P G P R PQ G+D + + S + +
Sbjct: 1218 ----MGPPGPPGPRGPQ----------GPNGADGPQGPPGSVGSVGGVGEKG-------E 1256
Query: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK-EMKLKGADGKTKIATPRGA- 474
PG + P PP G G K E KG G A P GA
Sbjct: 1257 PGEAGN----------PGPPGE----------AGVGGPKGERGEKGEAGPPGAAGPPGAK 1296
Query: 475 APPGQKG-QANATRIPAKTPPAPKTPPSSATKQV----------QRRPPPAGPRSERGEP 523
PPG G + N + P P P A + +P P GP E G P
Sbjct: 1297 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356
Query: 524 PKSGDRSGYSSPGSPGTPGSR 544
G R + G+ G G +
Sbjct: 1357 GPPGKRGPPGAAGAEGRQGEK 1377
Score = 46.6 bits (109), Expect = 9e-05
Identities = 124/516 (24%), Positives = 162/516 (31%), Gaps = 112/516 (21%)
Query: 99 EGTTAEEAGIG----DTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL-SHQLMSGM 153
+G E IG D P AG SG+ ++G L PG PG Q G
Sbjct: 795 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 854
Query: 154 PGAPLLP-----EGPREATRQPSG------TGPEDTEGGRHAPELLKHQLLGDLHQEGPP 202
G P P +G R +P TGP + G R G + GP
Sbjct: 855 TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR-----------GPTGKPGP- 902
Query: 203 LKGAGGKERP----GSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPG 258
KG G + P G + V P+ P P +DG P R T G
Sbjct: 903 -KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP---GPPGKDGLPGHPGQRGET---G 955
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
F + P P + P GP+ G+ P+
Sbjct: 956 FQGKTGPPGPGGVVG----------PQGPT-----GETGPI------------------- 981
Query: 319 EEHLGRAAFPGAPGEGPEARGP-SLGEDTKEADLPEP---SEKQPAAAPRGKPVSR-VPQ 373
G PG PG E P + G++ + D P P S K A RG P R +P
Sbjct: 982 ----GERGHPGPPGPPGEQGLPGAAGKEGAKGD-PGPQGISGKDGPAGLRGFPGERGLPG 1036
Query: 374 LKARMVSKSKDGT-GSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP-GSSDPLIQPSSPAV 431
+ K +G G R SA T P P P P G P + +P
Sbjct: 1037 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG--PIGLPGRPGPQGPPGPAGEKGAPGE 1094
Query: 432 C-PEPPSSPKHVSSVTSRTGSSGAK-------------EMKLKGADGKTKIATPRGAAPP 477
P+ P+ V G +G E KG+ G P G PP
Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG--PP 1152
Query: 478 GQKGQANATRIPAKT-PPAPKTPPS-------SATKQVQRRPPPAGPRSERGEPPKSGDR 529
G +G A I P P+ + P P G + G P + G+
Sbjct: 1153 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1212
Query: 530 SGYSSPGSPGTPGSRS-RTPSLPTPPTREPKKVAVV 564
G PG PG R + P+ P P V V
Sbjct: 1213 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1248
Score = 39.7 bits (91), Expect = 0.011
Identities = 78/369 (21%), Positives = 107/369 (28%), Gaps = 59/369 (15%)
Query: 213 GSKEEVDEDRDVDESSPQDSPPSKASPA----------QDGRPPQTAAREATSIPGFPAE 262
G K + E V+ + PP A PA G P R PG P
Sbjct: 423 GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGA 482
Query: 263 GAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHL 322
+P P + + GP++ + Q+ QA +
Sbjct: 483 DGLPGPPGTMLMLPFRYGGDGSKGPTI--------------------SAQEAQAQAILQQ 522
Query: 323 GRAAFPGAPGE-GPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSK 381
R A G PG G R +G E + P PRG V P + +
Sbjct: 523 ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG-PRG--VQGPPGPTGKPGKR 579
Query: 382 SKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKH 441
+ G + P L G P + P P
Sbjct: 580 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP-----------QGPPGPPG 628
Query: 442 VSSVTSRTGSSGAKEMKLKGADGKTKIATPRGA-APPGQKGQANATRIPA-KTPPAPKTP 499
+ G G + L G G + PRG PGQ G A P K P+
Sbjct: 629 DDGMRGEDGEIGPRG--LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 686
Query: 500 PSSATKQ----VQRRPPPAGP------RSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPS 549
P +Q Q P P GP + +G+P +G PG PG G +
Sbjct: 687 PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 746
Query: 550 LPTPPTREP 558
L P + P
Sbjct: 747 LGPPGPQGP 755
Score = 34.7 bits (78), Expect = 0.35
Identities = 43/152 (28%), Positives = 50/152 (32%), Gaps = 22/152 (14%)
Query: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP 476
PGSS + P P P+ V TG G + GADG G
Sbjct: 546 PGSSGAKGESGDPG-----PQGPRGVQGPPGPTGKPGKRGRP--GADG--------GRGM 590
Query: 477 PGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPG 536
PG+ G A R P P + Q P P G RGE + G R G
Sbjct: 591 PGEPG-AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 643
Query: 537 SPGTPGSRSRTPSLPTPPTREPKKVAVVRTPP 568
PG G R TP +A V PP
Sbjct: 644 LPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP 675
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 74.7 bits (182), Expect = 3e-13
Identities = 110/448 (24%), Positives = 148/448 (33%), Gaps = 88/448 (19%)
Query: 141 GPPGLSHQLMSGMPGAPLLPEGPR-EATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQE 199
G P G P P P+GP + QP G P + P+ G +
Sbjct: 38 GAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ-------GGNKPQ 90
Query: 200 GPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKAS--PAQDGRPPQTAAREATSIP 257
GPP G + G + D+ R SP+ SPP K P Q G PQ
Sbjct: 91 GPPPPG----KPQGPPPQGDKSR-----SPR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQ 140
Query: 258 GFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAH 317
G P +G +K P +P GP P +
Sbjct: 141 GPPPQGG--------NKPQGPPPPGKPQGPP--------------------PQGDNKSRS 172
Query: 318 SEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKAR 377
S G+ P G G + +GP + P+ K P GKP PQ
Sbjct: 173 SRSPPGKPQGPPPQG-GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD-- 229
Query: 378 MVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSD-PLIQPSSPAVCPEPP 436
+KS+ K + N+P P P PG P Q + P PP
Sbjct: 230 --NKSQSARSPPGKPQGPPPQGG-----NQPQGPP--PPPGKPQGPPPQGGNKPQGPPPP 280
Query: 437 SSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAP 496
P+ G+K + GK P+G P G N + P P P
Sbjct: 281 GKPQ------GPPPQGGSKSRSSRSPPGK-----PQGPPPQG----GNQPQGPPPPPGKP 325
Query: 497 KTPPSSATKQVQRRPPPAGPRSERGEPPKSGD--RSGYSSPGSP-GTPGSRSRTPSLPTP 553
+ PP + Q PPP P+ G PP+ G RS S PG P G P P P P
Sbjct: 326 QGPPPQGGNKPQGPPPPGKPQ---GPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382
Query: 554 PT----REPK--KVAVVRTPPKSPSSAK 575
P ++P+ + PP+ P +
Sbjct: 383 PAGGNPQQPQAPPAGQPQGPPRPPQGGR 410
Score = 70.1 bits (170), Expect = 7e-12
Identities = 108/456 (23%), Positives = 153/456 (33%), Gaps = 72/456 (15%)
Query: 104 EEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGP 163
E+ ++PSL AG+ P G +G P PPG + P P+GP
Sbjct: 21 EDVSQEESPSL---IAGNPQGAPPQGGNKPQG---PPSPPG---KPQGPPPQGGNQPQGP 71
Query: 164 REATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRD 223
+P G P+ + P K Q GPP +G + +
Sbjct: 72 PPPPGKPQGPPPQGGNKPQGPPPPGKPQ--------GPPPQGDKSRSPRSPPGKPQGPPP 123
Query: 224 VDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASE 283
+ PQ PP P G PPQ + P +G P P S+ P +
Sbjct: 124 QGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQG--PPPQGDNKSRSSRSPPGK 179
Query: 284 PDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPG--EGPEARGPS 341
P GP P P K Q + + P PG +GP +G +
Sbjct: 180 PQGPPPQGGNQPQGP---------PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN 230
Query: 342 LGEDTK----EADLPEP---SEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAK 394
+ + + P P ++ Q P GKP PQ G K
Sbjct: 231 KSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ-----GGNKPQGPPPPGKPQG 285
Query: 395 TSTRSSAKTLKNR-PCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSG 453
+ +K+ +R P P+ P P + QP P P PP P+ G
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQGGN---QPQGP---PPPPGKPQ------------G 327
Query: 454 AKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA-PKTPPSSATKQVQRRPP 512
G P+G PP Q G + + A++PP P+ PP Q PP
Sbjct: 328 PPPQGGNKPQGPPPPGKPQG--PPPQGGSKSRS---ARSPPGKPQGPPQQEGNNPQGPPP 382
Query: 513 PAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTP 548
PAG ++ + P +G G P G P SR P
Sbjct: 383 PAGGNPQQPQAPPAGQPQGPPRPPQGGRP---SRPP 415
Score = 67.8 bits (164), Expect = 4e-11
Identities = 87/363 (23%), Positives = 123/363 (33%), Gaps = 68/363 (18%)
Query: 214 SKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLS 273
S + ++ED +ES + + +P Q G PQ G P +G
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGG--------- 65
Query: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQA---HSEEHLGRAAFPGA 330
++P GP K Q P + + P K Q ++ + PG
Sbjct: 66 --------NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK 117
Query: 331 PGEGP------EARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKD 384
P +GP + +GP + P+ K P GKP PQ
Sbjct: 118 P-QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ----------- 165
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSS 444
D K+++S K P+ P P + QP P P PP P+
Sbjct: 166 ----GDNKSRSSRSPPGK---------PQGPPPQGGN---QPQGP---PPPPGKPQGPPP 206
Query: 445 VTSRTGSSGAKEMKLKG----ADGKTKIATPRGAAPPGQKGQA-NATRIPAKTPPAPKTP 499
K +G D K++ A P G Q N + P P P+ P
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 266
Query: 500 PSSATKQVQRRPPPAGPRSERGEPPKSG--DRSGYSSPGSP-GTPGSRSRTPSLPTPPTR 556
P + Q PPP P+ G PP+ G RS S PG P G P P P PP
Sbjct: 267 PPQGGNKPQGPPPPGKPQ---GPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323
Query: 557 EPK 559
+P+
Sbjct: 324 KPQ 326
Score = 30.8 bits (68), Expect = 5.0
Identities = 26/92 (28%), Positives = 31/92 (33%), Gaps = 7/92 (7%)
Query: 500 PSSATKQVQRRPP-----PAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 554
PS Q PP P GP S G+P + G G P PG P
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88
Query: 555 TREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 586
+ P + PP P KSR +P P
Sbjct: 89 PQGPPPPGKPQGPP--PQGDKSRSPRSPPGKP 118
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.127 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,947,363
Number of Sequences: 37866
Number of extensions: 2837946
Number of successful extensions: 29598
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 369
Number of HSP's successfully gapped in prelim test: 1952
Number of HSP's that attempted gapping in prelim test: 12328
Number of HSP's gapped (non-prelim): 9485
length of query: 776
length of database: 18,247,518
effective HSP length: 110
effective length of query: 666
effective length of database: 14,082,258
effective search space: 9378783828
effective search space used: 9378783828
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.