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Search of human proteins with 171916097
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|171916097 repetin [Homo sapiens]
(784 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|171916097 repetin [Homo sapiens] 1670 0.0
gi|62122917 filaggrin family member 2 [Homo sapiens] 201 3e-51
gi|57864582 hornerin [Homo sapiens] 199 8e-51
gi|60097902 filaggrin [Homo sapiens] 175 2e-43
gi|148746195 trichohyalin [Homo sapiens] 170 4e-42
gi|7706635 cornulin [Homo sapiens] 128 2e-29
gi|56606114 trichohyalin-like 1 [Homo sapiens] 86 2e-16
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 84 7e-16
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 81 3e-15
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 78 3e-14
gi|221316609 sperm-associated cation channel 1 [Homo sapiens] 75 2e-13
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 75 2e-13
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 75 2e-13
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 75 3e-13
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa... 73 1e-12
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 72 3e-12
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 71 3e-12
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 67 8e-11
gi|5454034 S100 calcium-binding protein, beta [Homo sapiens] 67 8e-11
gi|44890059 involucrin [Homo sapiens] 66 1e-10
gi|4504487 histidine rich calcium binding protein precursor [Hom... 66 1e-10
gi|5454032 S100 calcium binding protein A1 [Homo sapiens] 64 7e-10
gi|39777614 SS18-like protein 1 [Homo sapiens] 63 1e-09
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 62 3e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 59 2e-08
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 58 3e-08
gi|56117846 synovial sarcoma translocation, chromosome 18 isofor... 58 3e-08
gi|5174663 S100 calcium binding protein P [Homo sapiens] 58 4e-08
gi|221316599 chromogranin B precursor [Homo sapiens] 58 4e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 57 7e-08
>gi|171916097 repetin [Homo sapiens]
Length = 784
Score = 1670 bits (4326), Expect = 0.0
Identities = 784/784 (100%), Positives = 784/784 (100%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL
Sbjct: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ 120
LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ
Sbjct: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ 120
Query: 121 HRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDS 180
HRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDS
Sbjct: 121 HRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDS 180
Query: 181 HHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHY 240
HHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHY
Sbjct: 181 HHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHY 240
Query: 241 GQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDR 300
GQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDR
Sbjct: 241 GQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDR 300
Query: 301 QDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNR 360
QDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNR
Sbjct: 301 QDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNR 360
Query: 361 QGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDR 420
QGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDR
Sbjct: 361 QGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDR 420
Query: 421 QGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDK 480
QGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDK
Sbjct: 421 QGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDK 480
Query: 481 QGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR 540
QGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR
Sbjct: 481 QGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR 540
Query: 541 QGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQG 600
QGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQG
Sbjct: 541 QGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQG 600
Query: 601 TEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQH 660
TEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQH
Sbjct: 601 TEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQH 660
Query: 661 KLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHE 720
KLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHE
Sbjct: 661 KLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHE 720
Query: 721 SQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQ 780
SQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQ
Sbjct: 721 SQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQ 780
Query: 781 NHQR 784
NHQR
Sbjct: 781 NHQR 784
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 201 bits (510), Expect = 3e-51
Identities = 228/807 (28%), Positives = 336/807 (41%), Gaps = 112/807 (13%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
M LL S+++VIDVF+KY K +G+C L K ELK+LL E +L+ P+DP+TV+ I+++
Sbjct: 1 MTDLLRSVVTVIDVFYKYTKQDGECGTLSKGELKELLEKELHPVLKNPDDPDTVDVIMHM 60
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ 120
LD+D D +DF E+LL++F+L AC +K+ +K + CK G+ +
Sbjct: 61 LDRDHDRRLDFTEFLLMIFKLTMAC-NKVLSKEY----------------CKASGSKKHR 103
Query: 121 HRQRHEEERQNSHHSQ---PERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQD 177
RH+EE + + P + G H E ++ G S + H S R
Sbjct: 104 RGHRHQEEESETEEDEEDTPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLG 163
Query: 178 RDSHHNQSERQDKDFSFDQSERQSQDSS-SGKKVSHKSTSGQAKWQGHIFALNRCEKPIQ 236
R N S +++ S + R S S SG K H S+S + + + + ++ + +
Sbjct: 164 RQG--NLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGE 221
Query: 237 DSHYGQSERHTQQS---------ETLGQASHFNQT--NQQKSGSYCGQSERLGQ------ 279
+ G ++ ET G S+ Q+ +QK GS C S G+
Sbjct: 222 EYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACG 281
Query: 280 ---ELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQ--------------GQSSHYSQT 322
GCG+ S + Q + Y Q+ Q GQ S Q
Sbjct: 282 YSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQP 341
Query: 323 DRQGQSSHYSQ----PDRQGQSSHYGQMDRKGQ-----CYHYDQTNRQ------------ 361
+ S YSQ GQ + G R G C Y Q
Sbjct: 342 ESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSC 401
Query: 362 GQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSH------YGQTERQGQSSHY 415
G+ S+ S N + YG +Q S T S GQT Q +S+
Sbjct: 402 GRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSS 461
Query: 416 SQMDRQGQGSHYGQT-------DRQGQSSHYGQ-PDRQGQNSHYGQTDR-QGQSSHYGQT 466
+ GS G+T GQSS +GQ GQ+S +GQ GQSS +GQ
Sbjct: 462 QSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQH 521
Query: 467 DR-QGQSSHYSQPDKQGQSSHYGKI-DRQDQSYHYGQPDGQGQSSHYGQTD-RQGQSFHY 523
GQSS + Q + + + S YG+ QS YGQ G ++S +GQ GQS +
Sbjct: 522 GSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQ-YGSRETSGFGQHGLGSGQSTGF 580
Query: 524 GQ-PDRQGQSSHYSQM-DRQGQSSHYGQTD-RQGQSSHYGQTDRQGQSYHYGQTDRQGQS 580
GQ GQSS + Q GQSS +GQ + R GQSS+ + QS YGQ + Q+
Sbjct: 581 GQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSR-QT 639
Query: 581 SHYIQSQTGEIQ--GQNKYFQGT-EGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQ-GF 636
S + Q +G Q G +Y G+ + + +V SG+S Q + G+ + GQ GF
Sbjct: 640 SGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQH-ESRSGHSSYGQHGF 698
Query: 637 QSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQS 696
S S G + S QH+L + Q G SS G + + QS
Sbjct: 699 GSSQSSGYGQHGSSSGQTSGFGQHELSS--GQSSSFGQHG-SGSGQSSGFGQHGSGSGQS 755
Query: 697 HGEGLSHWAEEEQGHQTWDRHSHESQE 723
G G E G ++ +HS S +
Sbjct: 756 SGFGQH---ESRSGQSSYGQHSSGSSQ 779
Score = 150 bits (378), Expect = 6e-36
Identities = 201/711 (28%), Positives = 275/711 (38%), Gaps = 85/711 (11%)
Query: 130 QNSHHSQPERQDGDSHHGQPERQDRDS----HHGQSEKQDRDSHHSQPERQDRDSHHNQS 185
Q+S Q E + G S +GQ S HG + H S + +
Sbjct: 602 QSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSG 661
Query: 186 ERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQD-SHYGQSE 244
Q F S Q S G+ H+S SG + + H F ++ Q S GQ+
Sbjct: 662 SGQSSGFGQHVSG-SGQSSGFGQ---HESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTS 717
Query: 245 RHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQS 304
Q + GQ+S F Q GS GQS GQ G G GQSS +GQ + +
Sbjct: 718 GFGQHELSSGQSSSFGQ-----HGSGSGQSSGFGQH-GSGS----GQSSGFGQHESRSGQ 767
Query: 305 YHYGQ-TDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQ 363
YGQ + QSS Y Q + S QS+ +GQ Y G
Sbjct: 768 SSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQ-------YGSGSGQSAGF 820
Query: 364 GSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDR-QDQSSHYGQT-ERQGQSSHYSQ-MDR 420
G H S GQSS +GQ +++ S YGQ QSS YGQ GQ+S + Q
Sbjct: 821 GQHGSG---SGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSS 877
Query: 421 QGQGSHYGQTDR-QGQSSHYGQPDR-QGQNSHYGQTDRQGQSSHYGQTDR-QGQSSHYSQ 477
GQ S +GQ GQSS +GQ GQ S +GQ + + S YGQ QSS Y Q
Sbjct: 878 SGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQ 937
Query: 478 P-DKQGQSSHYGKI-DRQDQSYHYGQP-DGQGQSSHYGQTDR-QGQSFHYGQPDRQGQSS 533
GQ+ +G+ QS +GQ G GQSS +GQ + G+S +GQ + + S
Sbjct: 938 HGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQS 997
Query: 534 HYSQMDR-QGQSSHYGQT-DRQGQSSHYGQ-TDRQGQSYHYGQTDR-QGQSSHYIQSQTG 589
+Y Q QSS YGQ GQ++ +GQ GQ +GQ QSS + Q TG
Sbjct: 998 NYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTG 1057
Query: 590 EIQG-----------QNKYFQGTEGTRKASYVEQ----SGRSGRLSQQTPGQ---EGYQN 631
Q Q+ Y Q G+ ++S Q SG++ Q PG G+
Sbjct: 1058 SGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQ 1117
Query: 632 QGQGF-QSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQ 690
G G QS Q+G + +QH + Q H QS Q
Sbjct: 1118 YGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQ-----HGTGSSQSSGCGQHESG 1172
Query: 691 AQTRQSHGEGLS----------HWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNH 740
+ S G+ +S H ++ Q S Q G + + +
Sbjct: 1173 SGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTV 1232
Query: 741 QRRDRQTH-------EHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
R TH H QS Q + QT R+R + + D + H +
Sbjct: 1233 HGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSK 1283
Score = 139 bits (350), Expect = 1e-32
Identities = 200/734 (27%), Positives = 280/734 (38%), Gaps = 98/734 (13%)
Query: 94 HGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPE----------RQDGD 143
H R+ Q GQ + + G RQ + S SQ + G
Sbjct: 761 HESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGF 820
Query: 144 SHHGQPERQDRD--SHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQS 201
HG Q H +S + H S + H S Q F +S
Sbjct: 821 GQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSS-SG 879
Query: 202 QDSSSGKKVSHKSTSGQAKW-------QGHIFALNRCEKPIQDSHYGQSERHTQQSETLG 254
Q S G+ H S SGQ+ G + E S YGQ + QS G
Sbjct: 880 QYSGFGQ---HGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYG 936
Query: 255 Q-ASHFNQT---NQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDR-QDQSYHYGQ 309
Q S QT Q +SGS GQS GQ G G GQSS +GQ + +S +GQ
Sbjct: 937 QHGSSSGQTFGFGQHRSGS--GQSSGFGQH-GSGS----GQSSGFGQHESGSGKSSGFGQ 989
Query: 310 TDRQGQSSHYSQTDR-QGQSSHYSQP-DRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHY 367
+ + S+Y Q QSS Y Q GQ++ +GQ + Y + G GS
Sbjct: 990 HESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQ--HRSSSGQYSGFGQHGSGSDQ 1047
Query: 368 SQPNRQ-----GQSSHYGQPDTQDQSSHYGQ-TDRQDQSSHYGQ-TERQGQSSHYSQ-MD 419
S Q GQSS +GQ +++ + S YGQ QSS YGQ GQ+S + Q
Sbjct: 1048 SSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRP 1107
Query: 420 RQGQGSHYGQ-TDRQGQSSHYGQ-PDRQGQNSHYGQTD-RQGQSSHYGQTDRQGQSSHYS 476
GQ S +GQ GQSS +GQ G++S + Q + R GQSS+ QSS
Sbjct: 1108 GSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCG 1167
Query: 477 QPDK-QGQSSHYGK-IDRQDQSYHYGQP-DGQGQSSHYGQ-TDRQGQSFHYGQPDRQGQS 532
Q + G ++ +G+ + D GQ GQS+ +GQ GQS GQ + Q
Sbjct: 1168 QHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVE 1227
Query: 533 SHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQ 592
S + R Q + +GQT + S G QGQS G + + S ++ E+
Sbjct: 1228 SGSTVHGR--QETTHGQTINTTRHSQSG----QGQSTQTGSRVTRRRRSSQSENSDSEVH 1281
Query: 593 GQNKYFQGTE-GTRKASYVEQSGRSGRLSQ-QTPGQ------EGYQNQGQGFQSRDSQQN 644
+ + T+ S+ +SG + R Q T GQ G+ GQ Q+ S+ +
Sbjct: 1282 SKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQT-GSRTS 1340
Query: 645 GHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHW 704
G Q + + + H G + S EQ H QA ++ E H
Sbjct: 1341 GRQRFSHSDATDSE--------------VHSGVSHRPHSQEQTHSQAGSQHGESESTVH- 1385
Query: 705 AEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDE-QNHQRRDRQTHEHEQSH-QRRDRQTH 762
HE+ G G H Q+ QR R T H + D + H
Sbjct: 1386 ------------ERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVH 1433
Query: 763 EDKQNRQRRDRQTH 776
+R + QTH
Sbjct: 1434 SGGSHRPQSQEQTH 1447
Score = 135 bits (340), Expect = 1e-31
Identities = 190/703 (27%), Positives = 266/703 (37%), Gaps = 79/703 (11%)
Query: 85 CYHKLDNKSHGGRTSQQER--------GQEGAQDCKFPGNTGRQHRQRHEEE-----RQN 131
C + +G R + Q + G + C G+ G Q + E R +
Sbjct: 346 CSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFS 405
Query: 132 SHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRD-SHHSQPERQDRDSHHNQSERQDK 190
+ S E D + + HG Q H Q H + S +
Sbjct: 406 NSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQS-- 463
Query: 191 DFSFDQSERQSQDSSSGKKVS---HKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT 247
+DQ SSSGK H S SGQ+ G S GQS
Sbjct: 464 -LGYDQ-----HGSSSGKTSGFGQHGSGSGQSSGFGQC-----------GSGSGQSSGFG 506
Query: 248 QQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDR-QDQSYH 306
Q GQ+S F Q GS GQS G GQ + + + S YGQ QS
Sbjct: 507 QHGSVSGQSSGFGQ-----HGSVSGQSS------GFGQHESRSRQSSYGQHGSGSSQSSG 555
Query: 307 YGQTDRQGQSSHYSQTDRQGQSSHYSQ-PDRQGQSSHYGQMDR-KGQCYHYDQ-TNRQGQ 363
YGQ + S GQS+ + Q GQSS +GQ GQ + Q +R GQ
Sbjct: 556 YGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQ 615
Query: 364 GSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDR-QDQSSHYGQT-ERQGQSSHYSQ-MDR 420
S+ + QSS YGQ ++ Q+S +GQ QS+ +GQ GQSS + Q +
Sbjct: 616 SSYGQHSSGSSQSSGYGQHGSR-QTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSG 674
Query: 421 QGQGSHYGQTDRQGQSSHYGQPD-RQGQNSHYGQT-DRQGQSSHYGQTD-RQGQSSHYSQ 477
GQ S +GQ + + S YGQ Q+S YGQ GQ+S +GQ + GQSS + Q
Sbjct: 675 SGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQ 734
Query: 478 PDK-QGQSSHYGKIDR-QDQSYHYGQPDGQGQSSHYGQ-TDRQGQSFHYGQPDRQGQSSH 534
GQSS +G+ QS +GQ + + S YGQ + QS YGQ + S
Sbjct: 735 HGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF 794
Query: 535 YSQMDRQGQSSHYGQTDR-QGQSSHYGQTDR-QGQSYHYGQTDRQGQSSHYIQSQTGEIQ 592
QS+ +GQ GQS+ +GQ GQS +GQ + + S Y Q +G Q
Sbjct: 795 GQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQ 854
Query: 593 GQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGF-QSRDSQQNGHQVWEP 651
G+ + + + + SG+ S G+ G G QS Q+G +
Sbjct: 855 SSGYGQHGSSSGQTSGFGQHRSSSGQYS-------GFGQHGSGSGQSSGFGQHGTGSGQY 907
Query: 652 EEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGH 711
QH + Q S SS G + + Q+ G G H + Q
Sbjct: 908 SGFGQHESRSHQSSYGQH-------GSGSSQSSGYGQHGSSSGQTFGFG-QHRSGSGQSS 959
Query: 712 QTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSH 754
S Q G + + K Q R + + H
Sbjct: 960 GFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQH 1002
Score = 130 bits (326), Expect = 6e-30
Identities = 169/579 (29%), Positives = 239/579 (41%), Gaps = 45/579 (7%)
Query: 95 GGRTSQQERGQEGAQDCKFPGN-----TGRQHRQRHEEERQNSHHSQPERQDGDSHHGQP 149
GG+ +Q Q G Q G +G Q + E S +R G +GQP
Sbjct: 304 GGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQP 363
Query: 150 ERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSE-----RQDKDFSFDQSERQSQDS 204
+ G S+ + S + + H F + ++ S
Sbjct: 364 QNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGS 423
Query: 205 SSGKKVSHKST--SGQAKWQGHIFALNR-CEKPIQDSHYGQSERHTQQSETLGQASHFNQ 261
S T S + ++ H+ + C + +S QS + Q + G+ S F Q
Sbjct: 424 SQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQ--HESTSSQSLGYDQHGSSSGKTSGFGQ 481
Query: 262 TNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDR-QDQSYHYGQTDR-QGQSSHY 319
GS GQS GQ CG GQSS +GQ QS +GQ GQSS +
Sbjct: 482 -----HGSGSGQSSGFGQ---CGSGS--GQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGF 531
Query: 320 SQTDRQGQSSHYSQPDR-QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQ-PNRQGQSS 377
Q + + + S Y Q QSS YGQ + GQ + + Q + GQSS
Sbjct: 532 GQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSS 591
Query: 378 HYGQPDT-QDQSSHYGQTDRQDQSSHYGQ-TERQGQSSHYSQMDRQGQGSHYGQTDR-QG 434
+GQ + QSS +GQ + + S YGQ + QSS Y Q + Q S +GQ
Sbjct: 592 GFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSR-QTSGFGQHGSGSS 650
Query: 435 QSSHYGQ-PDRQGQNSHYGQ-TDRQGQSSHYGQTD-RQGQSSHYSQPDKQGQSSHYGKID 491
QS+ +GQ GQ+S +GQ GQSS +GQ + R G SS+ QSS YG+
Sbjct: 651 QSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHG 710
Query: 492 RQD-QSYHYGQPD-GQGQSSHYGQTDR-QGQSFHYGQPDR-QGQSSHYSQMD-RQGQSSH 546
Q+ +GQ + GQSS +GQ GQS +GQ GQSS + Q + R GQSS+
Sbjct: 711 SSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770
Query: 547 YGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYF--QGTEGT 604
+ QSS YGQ + Q+ +GQ G S Q G GQ+ F G+
Sbjct: 771 GQHSSGSSQSSGYGQHGSR-QTSGFGQ-HGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSG 828
Query: 605 RKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQ 643
+ + + + RS + S G Q+ G G S Q
Sbjct: 829 QSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQ 867
Score = 120 bits (302), Expect = 4e-27
Identities = 177/720 (24%), Positives = 267/720 (37%), Gaps = 92/720 (12%)
Query: 93 SHGGRTSQQERGQEGAQ----DCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQ 148
SH ++ +Q GQ G+Q G G H Q + R +H Q G S G+
Sbjct: 1437 SHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGR 1496
Query: 149 PERQDRDSHHGQSEKQDRDSH-HSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSG 207
R S SE SH HS S H +SE D + Q+ D++
Sbjct: 1497 --RGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHD-RHRITHGQTGDTTRH 1553
Query: 208 KKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQ----TN 263
H+ T+ + E + H G S R + T GQA ++ T
Sbjct: 1554 SYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTV 1613
Query: 264 QQKSGSYCGQSERLGQELGCGQTDRQGQSSHYG-QTDRQDQSYHYGQTDRQGQS----SH 318
++ G+ GQ +G G + GQS+ G +T + +S H +D + S +H
Sbjct: 1614 HERHGTTHGQ---IGDTTGHSHSG-HGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTH 1669
Query: 319 YSQTDRQGQSSHYSQ----PDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQG 374
T Q S H P+R G + + YH+ T + G S+ +
Sbjct: 1670 TGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTG-----SRTTGRR 1724
Query: 375 QSSHYGQPDTQDQS----SHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQT 430
S H D++ S +H G T Q +S H G++E H G+ +GQT
Sbjct: 1725 GSGHSEYSDSEGYSGVSHTHSGHTHGQARSQH-GESESIVHERH---------GTIHGQT 1774
Query: 431 DRQGQSSHYGQPDRQGQNSHYG-QTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQS----- 484
+ +H G GQ++ G +T + S H +D +G S +P +G +
Sbjct: 1775 GDTTRHAHSG----HGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAG 1830
Query: 485 SHYGK----IDRQDQSYH--YGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQM 538
S +G+ +D + + H G G QS H GQ+ + G S + +SS S++
Sbjct: 1831 SQHGESESIVDERHGTTHGQTGDTSGHSQSGH-GQSTQSGSSTTGRRRSGHSESSD-SEV 1888
Query: 539 DRQGQSSHYGQTDRQGQSSHYGQTD----RQGQSYH--YGQTDRQGQSSHYIQSQTGEIQ 592
G +H G T Q +S H G+++ ++ Q+ H G T G SH QTG
Sbjct: 1889 HSGGSHTHSGHTHSQARSQH-GESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTG--- 1944
Query: 593 GQNKYFQGTEGTRKASYVEQSGRSG---RLSQQTPGQEG--YQNQGQGFQSRDSQQNGHQ 647
G G+ + Y + G SG S T GQ G Y G R +G
Sbjct: 1945 ---SRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQT 2001
Query: 648 VWEPEEDSQHHQHKLLAQIQQ--ERPLCHKGRDWQSCSSEQGHR-QAQTRQSHGEGLSHW 704
D+ H H Q Q R + S +GH + T H G +
Sbjct: 2002 A-----DTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGS 2056
Query: 705 AEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDE-QNHQRRDRQTHEHEQSH-QRRDRQTH 762
E G +RH + G G R H Q+ QR R H + D + H
Sbjct: 2057 QHGESGSSVHERHG--TTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVH 2114
Score = 110 bits (275), Expect = 5e-24
Identities = 179/762 (23%), Positives = 268/762 (35%), Gaps = 110/762 (14%)
Query: 84 ACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQR-HEEERQNSHHSQPERQDG 142
A YH + G T+ + RG ++ ++G H H + S H + E
Sbjct: 1479 AHYHHGKSTQRGSSTTGR-RGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIH 1537
Query: 143 DSH---HGQPERQDRDSHHGQSEKQDRDSHH------SQPERQDRDSHHNQSER-QDKDF 192
D H HGQ R S+ G + S S E D + H S R ++
Sbjct: 1538 DRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREH 1597
Query: 193 SFDQSERQSQDSSSGKKVSHKSTSGQA------KWQGHIFALNRCEKPIQDSHYGQSERH 246
++ Q+ Q ++ H +T GQ GH + R + SE
Sbjct: 1598 TYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESS 1657
Query: 247 TQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTD--RQDQS 304
+ + +H T+ Q +GS GQSE + E R G + +GQT +
Sbjct: 1658 DSEVHSGVSHTHTGHTHGQ-AGSQHGQSESIVPE-------RHGTT--HGQTGDTTRHAH 1707
Query: 305 YHYGQTDRQGQ-------SSHYSQTDRQGQS--SHYSQPDRQGQS-SHYGQMDRKGQCYH 354
YH+G T + G S H +D +G S SH GQ+ S +G+ + H
Sbjct: 1708 YHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERH 1767
Query: 355 YDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSH 414
+ G + ++ GQS+ G T +SS G ++ D H G ++R H
Sbjct: 1768 GTIHGQTGDTTRHAHSGH-GQSTQTGSRTTGRRSS--GHSEYSDSEGHSGFSQRPHSRGH 1824
Query: 415 YSQMDRQGQ-GSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYG-QTDRQGQS 472
GQ GS +G+++ H + G S + Q+ GQS+ G T + +S
Sbjct: 1825 -----THGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSG-HGQSTQSGSSTTGRRRS 1878
Query: 473 SHYSQPDKQ----GQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPD- 527
H D + G +H G Q +S H G+ + H + G + +G P
Sbjct: 1879 GHSESSDSEVHSGGSHTHSGHTHSQARSQH-GESESTVHKRHQTTHGQTGDTTEHGHPSH 1937
Query: 528 ------------RQGQSSHYSQMDRQGQS----SHYGQTDRQGQSSHYGQTDRQGQSYH- 570
R+G S H D +G S +H G T Q SHY ++ H
Sbjct: 1938 GQTIQTGSRTTGRRG-SGHSEYSDSEGPSGVSHTHSGHTHGQA-GSHYPESGSSVHERHG 1995
Query: 571 --YGQ---TDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSG---RLSQQ 622
+GQ T R G S H +Q G G + + Y + G SG S
Sbjct: 1996 TTHGQTADTTRHGHSGHGQSTQRG------SRTTGRRASGHSEYSDSEGHSGVSHTHSGH 2049
Query: 623 TPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQ--ERPLCHKGRDWQ 680
GQ G Q+ G + H D+ H H Q Q R +G
Sbjct: 2050 AHGQAGSQHGESGSSVHERHGTTH---GQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHS 2106
Query: 681 SCSSEQ----------GHRQAQTRQSHGEGLS--HWAEEEQGHQTWD--RHSHESQEGPC 726
S + GH Q R HGE S H + QT D RH
Sbjct: 2107 ESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQST 2166
Query: 727 GTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNR 768
T R T + +H + H ++ TH +R
Sbjct: 2167 QTGSRTTGRQRSSHS-ESSDSEVHSEASPTHSGHTHSQAGSR 2207
Score = 105 bits (263), Expect = 1e-22
Identities = 157/619 (25%), Positives = 216/619 (34%), Gaps = 101/619 (16%)
Query: 90 DNKSHGGRTSQQE-----RGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQP----ERQ 140
D++ H G + + GQ G+Q + +H H + S HSQ Q
Sbjct: 1808 DSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQ 1867
Query: 141 DGDS-----HHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFD 195
G S G E D + H G S +H SQ Q +S +R
Sbjct: 1868 SGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTH-SQARSQHGESESTVHKRHQTTHGQT 1926
Query: 196 QSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQ 255
+ S G+ + S + + GH DS HT T GQ
Sbjct: 1927 GDTTEHGHPSHGQTIQTGSRTTGRRGSGH--------SEYSDSEGPSGVSHTHSGHTHGQ 1978
Query: 256 A-SHFNQTNQ---QKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQ------SY 305
A SH+ ++ ++ G+ GQ+ T R G S H T R + S
Sbjct: 1979 AGSHYPESGSSVHERHGTTHGQT---------ADTTRHGHSGHGQSTQRGSRTTGRRASG 2029
Query: 306 HYGQTDRQGQS--SHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQ 363
H +D +G S SH GQ+ SQ G S H GQ + G
Sbjct: 2030 HSEYSDSEGHSGVSHTHSGHAHGQAG--SQHGESGSSVHERHGTTHGQTGDTTRHAHSGH 2087
Query: 364 GSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSH-YGQTERQGQSSHYSQMDRQG 422
G + +R G ++ D H G + S H YGQ Q S + RQG
Sbjct: 2088 GQSTQRGSRTAGRRGSGHSESSDSEVHSGVS--HTHSGHTYGQARSQHGESGSAIHGRQG 2145
Query: 423 Q-GSHYGQTDRQGQSSHYGQPDRQGQNS-----------------------HYGQTDRQG 458
G T R GQS H GQ + G + H G T Q
Sbjct: 2146 TIHGQTGDTTRHGQSGH-GQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQA 2204
Query: 459 QSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQG 518
S H GQ+ G S H Q GQ+ + Y YGQ +G + T R+G
Sbjct: 2205 GSRH-GQS---GSSGHGRQGTTHGQTGD----TTRHAHYGYGQSTQRGSRT----TGRRG 2252
Query: 519 QSFHYGQPDRQGQS--SHYSQMDRQGQSSHYGQTDRQGQSSHYGQTD-RQGQSYHYGQTD 575
S H D + S SH QGQ+ G RQ S+ +G+ + GQ+ G T
Sbjct: 2253 -SGHSESSDSEVHSWGSHTHSGHIQGQA---GSQQRQPGSTVHGRLETTHGQT---GDTT 2305
Query: 576 RQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQG 635
R G S + +QTG + +FQ R+ Q + G P + Y + G G
Sbjct: 2306 RHGHSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYG---PAEYDYGHTGYG 2362
Query: 636 FQ--SRDSQQNGHQVWEPE 652
SR S N H W +
Sbjct: 2363 PSGGSRKSISNSHLSWSTD 2381
Score = 99.0 bits (245), Expect = 2e-20
Identities = 184/789 (23%), Positives = 268/789 (33%), Gaps = 157/789 (19%)
Query: 104 GQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEK 163
GQ +Q + + H + + HSQ + + R+ R S QSE
Sbjct: 1219 GQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSS---QSEN 1275
Query: 164 QDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSH-KSTSGQAKWQ 222
D + H R H K S + + + G H S GQ+
Sbjct: 1276 SDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQT 1335
Query: 223 GHIFA----LNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSE--- 275
G + + + + H G S R Q +T QA GS G+SE
Sbjct: 1336 GSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQA-----------GSQHGESESTV 1384
Query: 276 ---------RLGQELGCGQTDRQGQSSHYG-QTDRQDQSYHYGQTDRQGQS--SHYSQTD 323
+ G+ G G + GQS+ G +T + S H +D + S SH Q+
Sbjct: 1385 HERHETTYGQTGEATGHGHSG-HGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQ 1443
Query: 324 RQGQSSHYSQPDRQGQSSH------YGQMDRKGQCYHY----------DQTNRQGQG--- 364
Q SQ G + H +GQ + HY T R+G G
Sbjct: 1444 EQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSE 1503
Query: 365 SHYSQPNRQGQSSHYGQPDTQDQSSH--------------YGQTDRQDQSSHYG--QTER 408
S S+ + G +H G Q S H +GQT + S+ G QT +
Sbjct: 1504 SSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQ 1563
Query: 409 QG-------QSSHYSQMDRQ--GQGSH--------YGQTDRQGQSSHYGQPDRQG-QNSH 450
G ++SH D + GSH YGQ Q + + +R G +
Sbjct: 1564 TGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQ 1623
Query: 451 YGQTDRQGQSSHYGQTDRQG-------QSSHYSQPDKQGQS----SHYGKIDRQDQSYHY 499
G T S H GQ+ ++G +SSH D + S +H G Q S H
Sbjct: 1624 IGDTTGHSHSGH-GQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQH- 1681
Query: 500 GQPDGQGQSSH---YGQT--DRQGQSFHYGQPDRQGQ-------SSHYSQMDRQGQS--- 544
GQ + H +GQT + +H+G + G S H D +G S
Sbjct: 1682 GQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVS 1741
Query: 545 -SHYGQTDRQGQSSHYGQT-----DRQGQSY-HYGQTDRQGQSSHYIQSQTGEIQGQNKY 597
+H G T Q +S H G++ +R G + G T R S H +QTG
Sbjct: 1742 HTHSGHTHGQARSQH-GESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTG-------- 1792
Query: 598 FQGTEGTRKASYVEQSGRSGRLS-QQTPGQEGYQNQGQGFQSRDS-----QQNGHQVWEP 651
T G R + + E S G Q P G+ + G Q +S +++G +
Sbjct: 1793 -SRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQT 1851
Query: 652 EEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGH 711
+ S H Q G+ QS SS G R R H E S G
Sbjct: 1852 GDTSGHSQ-------------SGHGQSTQSGSSTTGRR----RSGHSES-SDSEVHSGGS 1893
Query: 712 QTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRR 771
T H+H G + HK Q + T EH + QT R+
Sbjct: 1894 HTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGS 1953
Query: 772 DRQTHEDEQ 780
+ D +
Sbjct: 1954 GHSEYSDSE 1962
Score = 93.6 bits (231), Expect = 6e-19
Identities = 140/523 (26%), Positives = 188/523 (35%), Gaps = 87/523 (16%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPER----QDG 142
H + +H G T Q R Q G + ++H+ H + + H P Q G
Sbjct: 1889 HSGGSHTHSGHTHSQARSQHGESE----STVHKRHQTTHGQTGDTTEHGHPSHGQTIQTG 1944
Query: 143 DSHHGQPERQDRDSHHGQSEKQDRDSH-HSQPERQDRDSHHNQS-----ERQDKDFSFDQ 196
G+ R S + SE SH HS SH+ +S ER
Sbjct: 1945 SRTTGR--RGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTA 2002
Query: 197 SERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQA 256
+ S G+ S + + GH S Y SE H+ S T
Sbjct: 2003 DTTRHGHSGHGQSTQRGSRTTGRRASGH-------------SEYSDSEGHSGVSHTHSGH 2049
Query: 257 SHFNQTNQQKSGSYCGQSERLGQELG-CGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQ 315
+H Q Q S ER G G G T R S H T R ++ R+G
Sbjct: 2050 AH-GQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRT-----AGRRG- 2102
Query: 316 SSHYSQTDRQGQS--SHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQ 373
S H +D + S SH GQ+ Q G H Q GQ R
Sbjct: 2103 SGHSESSDSEVHSGVSHTHSGHTYGQAR--SQHGESGSAIHGRQGTIHGQTG---DTTRH 2157
Query: 374 GQSSHYGQPDT------QDQSSHYGQTDRQDQS----SHYGQTERQGQSSHYSQMDRQG- 422
GQS H T + +SSH +D + S +H G T Q S H Q G
Sbjct: 2158 GQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRH-GQSGSSGH 2216
Query: 423 --QGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQ--TDRQGQSSHYGQTDRQGQS--SHYS 476
QG+ +GQT + +HYG GQ++ G T R+G S H +D + S SH
Sbjct: 2217 GRQGTTHGQTGDTTRHAHYG----YGQSTQRGSRTTGRRG-SGHSESSDSEVHSWGSHTH 2271
Query: 477 QPDKQGQSSHYGKIDRQDQSYHYGQPD-GQGQSSHYGQTDRQGQSFHYGQP----DRQGQ 531
QGQ+ G RQ S +G+ + GQ+ G T R G S YGQ R +
Sbjct: 2272 SGHIQGQA---GSQQRQPGSTVHGRLETTHGQT---GDTTRHGHS-GYGQSTQTGSRSSR 2324
Query: 532 SSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQT 574
+SH+ SH + R G S + Y YG T
Sbjct: 2325 ASHF--------QSHSSERQRHGSSQVWKHGSYGPAEYDYGHT 2359
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 199 bits (506), Expect = 8e-51
Identities = 237/804 (29%), Positives = 332/804 (41%), Gaps = 132/804 (16%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
M +LL +++VIDVF++YA +G+ L K ELK+LL EF IL+ PNDP+TV+ IL
Sbjct: 1 MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ 120
LD+D + +DF EYLL++F+LVQA +K+ K + C+ G+ R
Sbjct: 61 LDRDHNKKVDFTEYLLMIFKLVQA-RNKIIGKDY----------------CQVSGSKLRD 103
Query: 121 HRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPER----Q 176
+H+EE++ + + +RQ+ H + DS+ + S R +
Sbjct: 104 DTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQR 163
Query: 177 DRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQ 236
D HN Q + E+ S S + S SGQ+ G +
Sbjct: 164 DFSGQHNSYSGQSSSY----GEQNSDSHQSSGRGQCGSGSGQSPNYGQ-HGSGSGQSSSN 218
Query: 237 DSH---YGQSERHTQQSETLGQASHFNQ--TNQQKSGSYCGQSERLGQ-ELGCGQTDRQG 290
D+H GQS +Q + GQ+S ++Q + S Y R GQ G G
Sbjct: 219 DTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSG 278
Query: 291 QSSHYGQ---TDRQDQSY-HYGQTDRQGQ--------SSHYSQTDRQGQSSHYS-----Q 333
SS YGQ RQ + G RQ S H S + G S YS
Sbjct: 279 SSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHY 338
Query: 334 PDRQGQSSHYGQMDR-KGQCYHYDQTNRQGQGSHYSQPNRQ-----GQSSHYGQPDTQD- 386
GQ+S +GQ + GQ Y ++ G GS +S Q GQ+S GQ +
Sbjct: 339 ESGSGQTSGFGQHESGSGQSSGY---SKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR 395
Query: 387 QSSHYGQ--------TDRQDQSSHYGQTERQGQ-SSHYSQMDRQGQ-GSHYGQTDR---- 432
QSS YGQ + R SS GQ+ GQ S Q GQ G+ +G++
Sbjct: 396 QSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPY 455
Query: 433 ---QGQSSHYGQPDRQGQNSHYGQTDR---QGQSSHYGQ-TDRQGQSSH-YSQPDKQGQS 484
G SS +G + ++S G T G SS +GQ R GQSS Q G S
Sbjct: 456 VSGSGYSSGFGHHESSSEHSS-GYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS 514
Query: 485 SHYGKI---DRQDQSY-HYGQPDGQGQSSHYGQTD---RQGQSF---HYG---------- 524
S YG+ RQ + +G GQ S G+ + RQ S+ YG
Sbjct: 515 SSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPY 574
Query: 525 ------------QPDRQGQSSHYSQM-DRQGQSSHYGQ-TDRQGQSSHYGQTD-RQGQSY 569
Q R GQSS Y Q G SS +GQ GQSS GQ GQS
Sbjct: 575 ESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSS 634
Query: 570 HYGQ-TDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTP-GQE 627
+GQ QSS Y Q +G Q ++ G++ +SY + SG S P G
Sbjct: 635 SHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSV 694
Query: 628 GYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQG 687
Q+ G G +S Q +G+ SQH + ++ H R QS SEQ
Sbjct: 695 SGQSSGFGHKSGSGQSSGY--------SQHGSGSSHSSGYRK----HGSRSGQSSRSEQH 742
Query: 688 HRQAQTRQSHGEGLSHWAEEEQGH 711
+ S+G+ S + + GH
Sbjct: 743 GSSSGLSSSYGQHGS-GSHQSSGH 765
Score = 134 bits (336), Expect = 4e-31
Identities = 198/672 (29%), Positives = 259/672 (38%), Gaps = 100/672 (14%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHH 146
H + HG R+ Q R ++ + G+ H Q+S H + + G H
Sbjct: 722 HSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSH----QSSGHGR--QGSGSGHS 775
Query: 147 GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSS 206
R S H S Q H S H+ Q F +S S
Sbjct: 776 PSRVRHGSSSGHSSSHGQ----HGSGTSCSSSCGHYESGSGQASGFG-------QHESGS 824
Query: 207 GKKVS-HKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQ---ASHFNQT 262
G+ S H S SG QG + + Q S GQ + + QS + GQ ASH + +
Sbjct: 825 GQGYSQHGSASGHFSSQGRHGSTSG-----QSSSSGQHDSSSGQSSSYGQHESASH-HAS 878
Query: 263 NQQKSGSYCGQSERLGQE-LGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQ 321
+ + GS GQS GQ G GQ+ G+ H + R S +G GQSS +
Sbjct: 879 GRGRHGSGSGQSPGHGQRGSGSGQSPSYGR--HGSGSGRSSSSGRHGSGS--GQSSGFGH 934
Query: 322 TDRQGQSSHYSQPDR-QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQP-NRQGQSSHY 379
GQSS Y+Q G SS Y Q +R GQ S Q + G SS Y
Sbjct: 935 KSSSGQSSGYTQHGSGSGHSSSYEQ-----------HGSRSGQSSRSEQHGSSSGSSSSY 983
Query: 380 GQPDTQDQSS----HYGQTDRQDQSSHYGQT-ERQGQSSHYSQMDRQGQG---SHYGQTD 431
GQ + + S +G Q S G+ GQSS Y R G G S
Sbjct: 984 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY-RSGSGWSSSRGPYES 1042
Query: 432 RQGQSSHYGQPD-RQGQNSHYGQT-DRQGQSSHYGQT-DRQGQSSHYSQPD-KQGQSSHY 487
G SS G + R GQ+S YGQ G SS +GQ GQSS Q GQSS +
Sbjct: 1043 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1102
Query: 488 GKIDR-QDQSYHYG-QPDGQGQSSHYGQTDRQG-QSFHYGQPDRQGQSSHYSQMDRQ--- 541
G+ QS YG Q G GQS +GQ QS YG R G S S Q
Sbjct: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG---RHGSGSGRSSSSGQHGS 1159
Query: 542 --GQSSHYGQTDRQ-GQSSHYGQTDR-QGQSYHYGQT-DRQGQSSHYIQSQTGEIQGQNK 596
G+SS +G + GQSS Y Q G S YGQ R GQSS + G G +
Sbjct: 1160 GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR--GERHGSSSGSSS 1217
Query: 597 YF-QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQ---NGHQVWEPE 652
++ Q G+R++S GR G S +P + G G G S Q +G
Sbjct: 1218 HYGQHGSGSRQSS---GHGRQGSGSGHSPSR-GRHGSGLGHSSSHGQHGSGSGRSSSRGP 1273
Query: 653 EDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQ 712
+S+ + Q + S GH A ++ HG G H+ + Q
Sbjct: 1274 YESRSGHSSVFGQHE----------------SGSGHSSAYSQ--HGSGSGHFCSQGQHGS 1315
Query: 713 TWDRHSHESQEG 724
T + S QEG
Sbjct: 1316 TSGQSSTFDQEG 1327
Score = 132 bits (331), Expect = 2e-30
Identities = 214/773 (27%), Positives = 271/773 (35%), Gaps = 171/773 (22%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHH 146
H + HG R+ Q RG+ + G QH + +S H Q
Sbjct: 487 HSSGHGQHGSRSGQSSRGERQGSSAGSSSSYG-QHGSGSRQSLGHSRHGSGSGQSPSPSR 545
Query: 147 GQPERQDRDSH------HGQSEKQDR------DSHHSQPERQDRDSHHNQSERQDKDFSF 194
G+ E R S +G R H S Q+ S + Q S
Sbjct: 546 GRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSG 605
Query: 195 DQSERQSQDSSSGKKVS---HKSTSGQAKWQG-HIFALNRCEK-PIQDSHYGQSERHTQQ 249
S S+SG+ S H +TSGQ+ G H ++ + Q S GQS +
Sbjct: 606 HSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665
Query: 250 SETLGQASHFNQ--------TNQQKSGSYCGQSERLGQELGCGQTDRQGQ----SSHY-- 295
G +S + Q ++ GS GQS G + G GQ+ Q SSH
Sbjct: 666 GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSG 725
Query: 296 --------GQTDRQDQ-------SYHYGQTDRQGQSSHYSQTD-RQGQSSHYSQPDRQGQ 339
GQ+ R +Q S YGQ G SH S RQG S +S P R
Sbjct: 726 YRKHGSRSGQSSRSEQHGSSSGLSSSYGQ---HGSGSHQSSGHGRQGSGSGHS-PSRVRH 781
Query: 340 SSHYGQMDRKGQ----------CYHYDQTNRQ---------GQGSHYSQP-NRQGQSSHY 379
S G GQ C HY+ + Q G G YSQ + G S
Sbjct: 782 GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
Query: 380 GQP-DTQDQSSHYGQTDRQD-QSSHYGQTERQGQSSHYSQMDRQGQGS-----HYGQTDR 432
G+ T QSS GQ D QSS YGQ E S H S R G GS H +
Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHE--SASHHASGRGRHGSGSGQSPGHGQRGSG 899
Query: 433 QGQSSHYGQPDR--------------QGQNSHYGQTDRQGQSSHYGQT------------ 466
GQS YG+ GQ+S +G GQSS Y Q
Sbjct: 900 SGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQ 959
Query: 467 --DRQGQSSHYSQP-DKQGQSSHYGKIDRQD-QSYHYGQP----------------DGQG 506
R GQSS Q G SS YG+ QS +GQ G G
Sbjct: 960 HGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 1019
Query: 507 QSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQM----DRQGQSSHYGQT-DRQGQSSHYGQ 561
QSS YG R G + + + S H S + R GQSS YGQ G SS +GQ
Sbjct: 1020 QSSSYGPY-RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 1078
Query: 562 T-DRQGQSYHYGQTDRQ-GQSSHYIQSQTGEIQGQNKYFQGT------------EGTRKA 607
GQS GQ GQSS + Q +G Q QG+ G+R++
Sbjct: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 1138
Query: 608 -SYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQI 666
SY SGR S + GQ G G G +S GH + S + QH
Sbjct: 1139 PSYGRHGSGSGRSS--SSGQHG---SGLG----ESSGFGHHESSSGQSSSYSQH------ 1183
Query: 667 QQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQG-HQTWDRHS 718
G S + G R Q+ + G S + G H + R S
Sbjct: 1184 -------GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQS 1229
Score = 130 bits (327), Expect = 5e-30
Identities = 202/679 (29%), Positives = 265/679 (39%), Gaps = 96/679 (14%)
Query: 91 NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPE 150
++S G++S + G+ G G + Q ER S R HG
Sbjct: 2110 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY---GQHGSGS 2166
Query: 151 RQDRDSHHGQSEKQDRDSHHSQPE-RQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKK 209
RQ S HG +Q S HS R S H+ S Q S S R +S SG
Sbjct: 2167 RQS--SGHG---RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG-- 2219
Query: 210 VSHKSTSGQAK-WQGHIFALNR--------CEKPIQDSHYGQSERHTQQSETLGQASHFN 260
H S GQ + GH A ++ C + S GQS Q+ + GQ+S
Sbjct: 2220 --HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 2277
Query: 261 Q--TNQQKSGSYCGQSERLGQELGCGQTDR-QGQSSHYGQ----TDRQDQSYHYGQTDRQ 313
Q + +S SY Q GQ G+ G SS YGQ + S +G
Sbjct: 2278 QHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS-- 2335
Query: 314 GQSSHYSQTDRQG-QSSHYSQPDR-QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPN 371
GQSS + + QSS Y+Q G SS Y Q H ++ + +G + +
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQ--------HGSRSGQSSRGERHGSSS 2387
Query: 372 RQGQSSHYGQPDTQDQSS----HYGQTDRQDQSSHYGQT-ERQGQSSHYSQMDRQGQGSH 426
G SS YGQ + + S +G Q S G+ GQSS YS G GS
Sbjct: 2388 --GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY---GSGSG 2442
Query: 427 YGQT-----DRQGQSSHYGQPD-RQGQNSHYGQT-DRQGQSSHYGQT-DRQGQSSHYSQP 478
+ + G SS G + R GQ+S YGQ G SS +GQ GQSS Q
Sbjct: 2443 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 2502
Query: 479 D-KQGQSSHYGKIDR-QDQSYHYG-QPDGQGQSSHYGQTDRQG-QSFHYGQPDRQGQSSH 534
GQSS +G+ QS YG Q G GQS +GQ QS YG R G S
Sbjct: 2503 GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG---RHGSGSG 2559
Query: 535 YSQMDRQ-----GQSSHYGQTDRQ-GQSSHYGQTDR-QGQSYHYGQT-DRQGQSSHYIQS 586
S Q G+SS +G + GQSS Y Q G S YGQ R GQSS
Sbjct: 2560 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR--GE 2617
Query: 587 QTGEIQGQNKYF-QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNG 645
+ G G + ++ Q G+R++S GR G S Q+P + G G G S Q
Sbjct: 2618 RHGSSSGSSSHYGQHGSGSRQSS---GHGRQGSGSGQSPSR-GRHGSGLGHSSSHGQHGS 2673
Query: 646 HQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWA 705
+ ++ E L H Q S GH A ++ HG G H+
Sbjct: 2674 GS------------GRSSSRGPYESRLGHSSVFGQH-ESGSGHSSAYSQ--HGSGSGHFC 2718
Query: 706 EEEQGHQTWDRHSHESQEG 724
+ Q T + S QEG
Sbjct: 2719 SQGQHGSTSGQSSTFDQEG 2737
Score = 124 bits (311), Expect = 3e-28
Identities = 199/679 (29%), Positives = 260/679 (38%), Gaps = 96/679 (14%)
Query: 91 NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPE 150
++S G++S + G+ G G + Q ER S R HG
Sbjct: 1640 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRY---GQHGSGS 1696
Query: 151 RQDRDSHHGQSEKQDRDSHHSQPERQDRDSH--HNQSERQDKDFSFDQSERQSQDSSSGK 208
RQ S HG+ S P R S H+ S Q S S R +S SG
Sbjct: 1697 RQS--SGHGRQGSGSGQS----PSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSG- 1749
Query: 209 KVSHKSTSGQAK-WQGHIFALNR--------CEKPIQDSHYGQSERHTQQSETLGQASHF 259
H S GQ + GH A ++ C + S GQS Q+ + GQ+S
Sbjct: 1750 ---HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 1806
Query: 260 NQTNQQKSGSYCGQSERLGQE-LGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSH 318
Q GS QS GQ+ G GQ+ +G+ +G SY + SS
Sbjct: 1807 GQ-----HGSGSSQSSSYGQQGSGSGQSPSRGR---HGSGSGHSSSYGQHGSGSGWSSSS 1858
Query: 319 YSQTDRQGQSSHYSQPDRQG-QSSHYGQMDR-KGQCYHYDQT-NRQGQGSHYSQP-NRQG 374
GQSS + + QSS Y Q G Y+Q +R GQ S Q + G
Sbjct: 1859 GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSG 1918
Query: 375 QSSHYGQPDTQDQSS----HYGQTDRQDQSSHYGQT-ERQGQSSHYSQMDRQGQGSHYGQ 429
SS YGQ + + S +G Q S G+ GQSS Y G GS +
Sbjct: 1919 SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY---GSGSGWSS 1975
Query: 430 T-----DRQGQSSHYGQPD-RQGQNSHYGQT-DRQGQSSHYGQT-DRQGQSSHYSQPD-K 480
+ G SS G + R GQ+S YGQ G SS +GQ GQSS Q
Sbjct: 1976 SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGAS 2035
Query: 481 QGQSSHYGKIDR-QDQSYHYG-QPDGQGQSSHYGQTDRQG-QSFHYGQPDRQGQSSHYSQ 537
GQSS +G+ QS YG Q G GQS +GQ QS YG R G S S
Sbjct: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG---RHGSGSGRSS 2092
Query: 538 MDRQ-----GQSSHYGQTDRQ-GQSSHYGQTDR-QGQSYHYGQT-DRQGQSSHYIQSQTG 589
Q G+SS +G + GQSS Y Q G S YGQ R GQSS + G
Sbjct: 2093 SSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR--GERHG 2150
Query: 590 EIQGQN-KYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQ---NG 645
G + +Y Q G+R++S GR G S +P + G G G S Q +G
Sbjct: 2151 SSSGSSSRYGQHGSGSRQSS---GHGRQGSGSGHSPSR-GRHGSGSGHSSSHGQHGSGSG 2206
Query: 646 HQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWA 705
+S+ + Q + S GH A ++ HG G H+
Sbjct: 2207 RSSSRGPYESRSGHSSVFGQHE----------------SGSGHSSAYSQ--HGSGSGHFC 2248
Query: 706 EEEQGHQTWDRHSHESQEG 724
+ Q T + S QEG
Sbjct: 2249 SQGQHGSTSGQSSTFDQEG 2267
Score = 118 bits (295), Expect = 2e-26
Identities = 198/705 (28%), Positives = 255/705 (36%), Gaps = 111/705 (15%)
Query: 87 HKLDNKSHG---GRTSQQE--RGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQD 141
H + HG GR+S + + G +G H + + S H + Q
Sbjct: 1254 HSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 1313
Query: 142 GDSHHGQPERQDRD-SHHGQSEKQD-RDSHHSQPE---RQDRDSHHNQSERQDKDFSFDQ 196
G S GQ D++ S GQS R S SQ R S + S + S
Sbjct: 1314 G-STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHS 1372
Query: 197 SERQSQDSSSGKKVS---HKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL 253
S S SG S H S SGQ+ GH +S QS TQ
Sbjct: 1373 SSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH-----------HESSSWQSSGCTQHGSGS 1421
Query: 254 GQASHFNQ--------TNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSY 305
G +S + Q + ++ GS G S GQ G G G H + +
Sbjct: 1422 GHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQH-GSGSRQSLGHGQHGSGSGQSPSPS 1480
Query: 306 HYGQTDRQGQSSHYS-----------QTDRQGQSSHYS----QPDRQGQSSHYGQMDRKG 350
GQSS YS + + SSH S + R GQSS YGQ
Sbjct: 1481 RGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSS 1540
Query: 351 --QCYHYDQTNRQGQGSHYSQPNRQ-GQSSHYGQPDT-QDQSSHYGQTDRQDQSSHYGQT 406
H + GQ S Q GQSS +GQ + QSS YG+ Q S GQ+
Sbjct: 1541 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR-----QGSGSGQS 1595
Query: 407 ERQGQSSHYSQMD----RQGQGSHYGQTDRQ-----GQSSHYGQPDRQ-GQNSHYGQTDR 456
GQ S+ R G GS + Q G+SS +G + GQ+S Y Q
Sbjct: 1596 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 1655
Query: 457 -QGQSSHYGQT-DRQGQSS----HYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSH 510
G SS YGQ R GQSS H S + +G RQ S H Q G GQS
Sbjct: 1656 GSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQS-SGHGRQGSGSGQSPS 1714
Query: 511 YGQTDRQ-GQSFHYGQPDR-QGQSSHYSQMD-RQGQSSHYGQTDR-QGQSSHYGQTDR-- 564
G+ G S +GQ G+SS + R G SS +GQ + G SS Y Q
Sbjct: 1715 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1774
Query: 565 -----QGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRL 619
QGQ +G T GQSS + Q + Q + G+ ++ +SY +Q SG
Sbjct: 1775 GHFCSQGQ---HGSTS--GQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG-- 1827
Query: 620 SQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDW 679
Q+P + G G G S Q W S H Q H+ W
Sbjct: 1828 --QSPSR-GRHGSGSGHSSSYGQHGSGSGWS--SSSGRHGS---GSGQSSGFGHHESSSW 1879
Query: 680 QSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEG 724
QS Q HG G H + EQ + S Q G
Sbjct: 1880 QSSGYTQ----------HGSGSGHSSSYEQHGSRSGQSSRGEQHG 1914
Score = 117 bits (293), Expect = 4e-26
Identities = 181/674 (26%), Positives = 248/674 (36%), Gaps = 78/674 (11%)
Query: 90 DNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQP 149
+ S G +S RG +Q + GR + + H S HG
Sbjct: 1326 EGSSTGQSSSYGHRGSGSSQSSGY----GRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSG 1381
Query: 150 ERQDRDS-HHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGK 208
S HG Q H + S++Q +S SS G+
Sbjct: 1382 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGE 1441
Query: 209 KVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSG 268
+ H S+SG + G + +R Q +GQ + QS + + H + + Q S
Sbjct: 1442 R--HGSSSGSSSSYGQHGSGSR-----QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1494
Query: 269 SYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQ--- 325
S G G ++ S + R QS YGQ G SS +S T Q
Sbjct: 1495 SPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQ---HGSSSGHSSTHGQHGS 1551
Query: 326 --GQSSHYSQPDRQ-GQSSHYGQMDR-KGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQ 381
GQSS Q GQSS +GQ Q Y RQG GS S + Q S
Sbjct: 1552 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY---GRQGSGSGQSPGHGQRGSGSRQS 1608
Query: 382 PDTQDQSSHYGQTDRQDQ-------SSHYGQTERQ-GQSSHYSQMDRQGQGSHYGQTDRQ 433
P S G++ Q SS +G E GQSS YSQ G GS
Sbjct: 1609 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ---HGSGS-------- 1657
Query: 434 GQSSHYGQP-DRQGQNSH---YGQTDRQGQSSHYGQ--TDRQGQSSHYSQPDKQGQSSHY 487
G SS YGQ R GQ+S +G + R SS YGQ + + S H Q GQS
Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRS--SSRYGQHGSGSRQSSGHGRQGSGSGQSPSR 1715
Query: 488 GKIDRQ--DQSYHYGQPDGQGQSSHYGQTD-RQGQSFHYGQPDR-QGQSSHYSQMDRQGQ 543
G+ S H G G+SS G + R G S +GQ + G SS YSQ
Sbjct: 1716 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQ--HGSG 1773
Query: 544 SSHYGQTDRQGQSSHYGQTDRQ-----GQSYHYGQTDR-QGQSSHYIQSQTGEIQGQNKY 597
S H+ + G +S T Q GQS +GQ QSS Y Q +G Q ++
Sbjct: 1774 SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRG 1833
Query: 598 FQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQH 657
G+ +SY + SG S G Q GF +S W+ +QH
Sbjct: 1834 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG-SGQSSGFGHHESSS-----WQSSGYTQH 1887
Query: 658 HQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRH 717
+ ++ H R QS EQ + + S+G+ S + + GH +H
Sbjct: 1888 GSGSGHSSSYEQ----HGSRSGQSSRGEQHGSSSGSSSSYGQHGS-GSRQSLGH---GQH 1939
Query: 718 SHESQEGPCGTQDR 731
S + P ++ R
Sbjct: 1940 GSGSGQSPSPSRGR 1953
Score = 115 bits (288), Expect = 2e-25
Identities = 195/694 (28%), Positives = 249/694 (35%), Gaps = 128/694 (18%)
Query: 87 HKLDNKSHGGRTSQQER-GQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSH 145
H + HG + Q GQ GA H Q Q+S + + G S
Sbjct: 1542 HSSTHGQHGSTSGQSSSCGQHGASS-----GQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1596
Query: 146 -HGQPERQDRDS----HHGQSEKQDRDS--HHSQPERQDRDSHHNQSERQDKDFSFDQSE 198
HGQ R S HG + S H S HH S Q +S +
Sbjct: 1597 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS----Q 1652
Query: 199 RQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASH 258
S S H S SGQ+ + +R S YGQ ++QS G
Sbjct: 1653 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSR-----SSSRYGQHGSGSRQSSGHG---- 1703
Query: 259 FNQTNQQKSGSYCGQSERLGQE-LGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSS 317
+ GS GQS G+ G G + GQ H + R Y R G SS
Sbjct: 1704 -------RQGSGSGQSPSRGRHGSGLGHSSSHGQ--HGSGSGRSSSRGPY--ESRSGHSS 1752
Query: 318 HYSQTDR-QGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQ-GQ 375
+ Q + G SS YSQ S H+ + G + GQ S + Q GQ
Sbjct: 1753 VFGQHESGSGHSSAYSQ--HGSGSGHFCSQGQHG--------STSGQSSTFDQEGSSTGQ 1802
Query: 376 SSHYGQPDT-QDQSSHYGQTDRQDQSSHYGQTERQGQ----SSHYSQMDRQGQGSHYGQT 430
SS +GQ + QSS YGQ Q S GQ+ +G+ S H S + G GS + +
Sbjct: 1803 SSSHGQHGSGSSQSSSYGQ-----QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 1857
Query: 431 DRQ-----GQSSHYGQPDRQG-QNSHYGQTDR-QGQSSHYGQT-DRQGQSSHYSQP-DKQ 481
+ GQSS +G + Q+S Y Q G SS Y Q R GQSS Q
Sbjct: 1858 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS 1917
Query: 482 GQSSHYGKIDRQD-QSYHYGQP----------------DGQGQSSHYGQ----------- 513
G SS YG+ QS +GQ G GQSS YG
Sbjct: 1918 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSR 1977
Query: 514 ---TDRQGQSFHYGQPD-RQGQSSHYSQM-DRQGQSSHYGQT-DRQGQSSHYGQTDRQ-G 566
G S G + R GQSS Y Q G SS +GQ GQSS GQ G
Sbjct: 1978 GPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSG 2037
Query: 567 QSYHYGQTDR-QGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPG 625
QS +GQ QSS Y + +G Q +G+ + SY SGR S + G
Sbjct: 2038 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS--SSG 2095
Query: 626 QEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSE 685
Q G G G +S GH + S + QH G S +
Sbjct: 2096 QHG---PGLG----ESSGFGHHESSSGQSSSYSQH-------------GSGSGHSSGYGQ 2135
Query: 686 QGHRQAQTRQSHGEGLSHWAEEEQG-HQTWDRHS 718
G R Q+ + G S + G H + R S
Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169
Score = 115 bits (287), Expect = 2e-25
Identities = 163/587 (27%), Positives = 220/587 (37%), Gaps = 62/587 (10%)
Query: 90 DNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQP 149
+ S G +S + G +Q + G+Q + + H S HG
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSY----GQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 2321
Query: 150 ERQDRDS-HHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGK 208
S HG Q H + + S++Q +S SS G+
Sbjct: 2322 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 2381
Query: 209 KVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSG 268
+ H S+SG + G + +R Q +GQ + QS + + H + + Q S
Sbjct: 2382 R--HGSSSGSSSSYGQHGSGSR-----QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 2434
Query: 269 SYCGQSERLGQELGCGQTDRQGQSSHYGQTD-RQDQSYHYGQTDRQGQSSHYSQTDRQ-- 325
S G G ++ G SS G + R QS YGQ G SS +S T Q
Sbjct: 2435 SPYGSGSGWSSSRGPYESG-SGHSSGLGHRESRSGQSSGYGQ---HGSSSGHSSTHGQHG 2490
Query: 326 ---GQSSHYSQPDRQ-GQSSHYGQMDR-KGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYG 380
GQSS Q GQSS +GQ Q Y RQG GS S + Q S
Sbjct: 2491 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY---GRQGSGSGQSPGHGQRGSGSRQ 2547
Query: 381 QPDTQDQSSHYGQTDRQDQ-------SSHYGQTERQ-GQSSHYSQMDR-QGQGSHYGQT- 430
P S G++ Q SS +G E GQSS YSQ G S YGQ
Sbjct: 2548 SPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 2607
Query: 431 DRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQ--TDRQGQSSHYSQPDKQGQSSHYG 488
R GQSS + +R G +S G SSHYGQ + + S H Q GQS G
Sbjct: 2608 SRSGQSS---RGERHGSSS--------GSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRG 2656
Query: 489 KIDRQ--DQSYHYGQPDGQGQSSHYGQTD-RQGQSFHYGQPDR-QGQSSHYSQMDRQGQS 544
+ S H G G+SS G + R G S +GQ + G SS YSQ S
Sbjct: 2657 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQ--HGSGS 2714
Query: 545 SHYGQTDRQGQSSHYGQTDRQ-----GQSYHYGQTDR-QGQSSHYIQSQTGEIQGQNKYF 598
H+ + G +S T Q GQS YG QSS Y + G Q +
Sbjct: 2715 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGR 2774
Query: 599 QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNG 645
G+ + +SY + SG+ S + G G + S +G
Sbjct: 2775 HGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDG 2821
Score = 111 bits (278), Expect = 2e-24
Identities = 189/695 (27%), Positives = 243/695 (34%), Gaps = 130/695 (18%)
Query: 87 HKLDNKSHGGRTSQQER-GQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSH 145
H + HG + Q GQ GA H Q Q+S + + G S
Sbjct: 2012 HSSTHGQHGSASGQSSSCGQHGASS-----GQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 2066
Query: 146 -HGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDS 204
HGQ R S QS R H S R H + F +S S
Sbjct: 2067 GHGQ-----RGSGSRQSPSYGR--HGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSS 2119
Query: 205 SSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQ--- 261
S H S SG + G S GQS R + + G +S + Q
Sbjct: 2120 YS----QHGSGSGHSSGYGQ-----------HGSRSGQSSRGERHGSSSGSSSRYGQHGS 2164
Query: 262 -----TNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQS 316
+ + GS G S G+ G G H + R Y R G S
Sbjct: 2165 GSRQSSGHGRQGSGSGHSPSRGRH-GSGSGHSSSHGQHGSGSGRSSSRGPY--ESRSGHS 2221
Query: 317 SHYSQTDR-QGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQ-G 374
S + Q + G SS YSQ S H+ + G + GQ S + Q G
Sbjct: 2222 SVFGQHESGSGHSSAYSQ--HGSGSGHFCSQGQHG--------STSGQSSTFDQEGSSTG 2271
Query: 375 QSSHYGQPDT-QDQSSHYGQTDRQDQSSHYGQTERQGQ----SSHYSQMDRQGQGSHYGQ 429
QSS +GQ + QSS YGQ Q S GQ+ +G+ S H S + G GS +
Sbjct: 2272 QSSSHGQHGSGSSQSSSYGQ-----QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 2326
Query: 430 TDRQ-----GQSSHYGQPDRQG-QNSHYGQTDR-QGQSSHYGQT-DRQGQSSHYSQP-DK 480
+ + GQSS +G + Q+S Y Q G SS Y Q R GQSS +
Sbjct: 2327 SSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSS 2386
Query: 481 QGQSSHYGKIDRQD-QSYHYGQP----------------DGQGQSSHYGQ---------- 513
G SS YG+ QS +GQ G GQSS Y
Sbjct: 2387 SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS 2446
Query: 514 ----TDRQGQSFHYGQPD-RQGQSSHYSQM-DRQGQSSHYGQT-DRQGQSSHYGQTDRQ- 565
G S G + R GQSS Y Q G SS +GQ GQSS GQ
Sbjct: 2447 RGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASS 2506
Query: 566 GQSYHYGQTDR-QGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTP 624
GQS +GQ QSS Y + +G Q +G+ + SY SGR S +
Sbjct: 2507 GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS--SS 2564
Query: 625 GQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSS 684
GQ G G G +S GH + S + QH G S
Sbjct: 2565 GQHG---SGLG----ESSGFGHHESSSGQSSSYSQH-------------GSGSGHSSGYG 2604
Query: 685 EQGHRQAQTRQSHGEGLSHWAEEEQG-HQTWDRHS 718
+ G R Q+ + G S + G H + R S
Sbjct: 2605 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQS 2639
Score = 108 bits (269), Expect = 2e-23
Identities = 195/683 (28%), Positives = 248/683 (36%), Gaps = 106/683 (15%)
Query: 87 HKLDNKSHGGRTSQQER-GQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSH 145
H + HG + Q GQ GA H Q Q+S + + G S
Sbjct: 1072 HSSTHGQHGSTSGQSSSCGQHGASS-----GQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1126
Query: 146 -HGQPERQDRDS----HHGQSEKQDRDS--HHSQPERQDRDSHHNQSERQDKDFSFDQSE 198
HGQ R S HG + S H S HH S Q +S +
Sbjct: 1127 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS----Q 1182
Query: 199 RQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQ--A 256
S S H S SGQ+ +G SHYGQ ++QS G+ +
Sbjct: 1183 HGSGSGHSSGYGQHGSRSGQSS-RGE----RHGSSSGSSSHYGQHGSGSRQSSGHGRQGS 1237
Query: 257 SHFNQTNQQKSGSYCGQSERLGQE-LGCGQTD-------RQGQSSHYGQTDRQDQSYHYG 308
+ ++ + GS G S GQ G G++ R G SS +GQ + S H
Sbjct: 1238 GSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ--HESGSGHSS 1295
Query: 309 QTDRQGQSSHYSQTDRQ-----GQSSHYSQPDRQ-GQSSHYGQMDRKGQCYHYDQTNRQG 362
+ G S + + Q GQSS + Q GQSS YG R R G
Sbjct: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGH--RGSGSSQSSGYGRHG 1353
Query: 363 QGSHYSQPNR------QGQSSHYGQPDTQD--QSSHYGQTDRQDQSSHYGQTERQG-QSS 413
GS S P+R G SS YGQ + SS QSS +G E QSS
Sbjct: 1354 AGSGQS-PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1412
Query: 414 HYSQMDR-QGQGSHYGQT-DRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQ 471
+Q G S Y Q R GQSS + +R G +S G SS YGQ +
Sbjct: 1413 GCTQHGSGSGHSSSYEQHGSRSGQSS---RGERHGSSS--------GSSSSYGQHGSGSR 1461
Query: 472 SS--HYSQPDKQGQS-----SHYGKIDRQDQSYH-YGQPDGQGQSSHYGQTDRQGQSFHY 523
S H GQS +G Q SY YG G G SS G + G S
Sbjct: 1462 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS--GSGWSSSRGPYE-SGSSHSS 1518
Query: 524 G---QPDRQGQSSHYSQM-DRQGQSSHYGQT-DRQGQSSHYGQTDRQ-GQSYHYGQTDR- 576
G + R GQSS Y Q G SS +GQ GQSS GQ GQS +GQ
Sbjct: 1519 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG 1578
Query: 577 QGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGF 636
QSS Y + +G Q +G+ + SY SGR S + GQ G G G
Sbjct: 1579 SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS--SSGQHG---SGLG- 1632
Query: 637 QSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQS 696
+S GH + S + QH G S + G R Q+ +
Sbjct: 1633 ---ESSGFGHHESSSGQSSSYSQH-------------GSGSGHSSGYGQHGSRSGQSSRG 1676
Query: 697 HGEGLSHWAEEEQG-HQTWDRHS 718
G S + G H + R S
Sbjct: 1677 ERHGSSSRSSSRYGQHGSGSRQS 1699
Score = 47.0 bits (110), Expect = 7e-05
Identities = 62/240 (25%), Positives = 80/240 (33%), Gaps = 23/240 (9%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHH 146
H HG R+ Q RG+ + + Q RQ+S H + G S
Sbjct: 2599 HSSGYGQHGSRSGQSSRGERHGSS----SGSSSHYGQHGSGSRQSSGHGRQGSGSGQS-- 2652
Query: 147 GQPERQDRDSH--HGQSEKQDRDSHHSQPERQDRDSH--HNQSERQDKDFSFDQSERQSQ 202
P R S H S Q R +S H+ Q + S S
Sbjct: 2653 --PSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQH 2710
Query: 203 DSSSGKKVS---HKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQ--AS 257
S SG S H STSGQ+ Q S YG + QS G+ A
Sbjct: 2711 GSGSGHFCSQGQHGSTSGQSSTFDQ-----EGSSTGQSSSYGHRGSGSSQSSGYGRHGAG 2765
Query: 258 HFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSS 317
+ + GS GQS GQ G G G S H + + SY G ++ G SS
Sbjct: 2766 SGQSLSHGRHGSGSGQSSSYGQH-GSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSS 2824
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 175 bits (443), Expect = 2e-43
Identities = 193/822 (23%), Positives = 314/822 (38%), Gaps = 101/822 (12%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
M+ LL +I ++I++F +Y+K + + L K+ELK+LL EF IL+ P+DP+ V+ ++
Sbjct: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACY------------HKLDNKSHGGRTSQQERGQEGA 108
LD D + IDF E+LL+VF+L QA Y HK SH + + + +E
Sbjct: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDK-HEDNKQEENK 119
Query: 109 QDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDS 168
++ K P + R++ ++ + R S P G H E+++R + +++
Sbjct: 120 ENRKRPSSLERRNNRKGNKGRSKS----PRETGGKRHESSSEKKERKGYSPTHREEEYGK 175
Query: 169 HHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKW--QGHIF 226
+H +++++ N + D + + +D+ G + KW GHI
Sbjct: 176 NHHNSSKKEKNKTEN-TRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIA 234
Query: 227 ALNRCEKPIQDSHYGQSERHTQQSETLGQ--------ASHFNQTNQQKSGSYCGQSERLG 278
IQD Y ++ ++++ + +S N++ + + Q R
Sbjct: 235 TY----YTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTR 290
Query: 279 QELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQG 338
+ G + + H +D H G R S + Q+ R G S + +
Sbjct: 291 KRRGSRVSQDRDSEGH-----SEDSERHSGSASRNHHGSAWEQS-RDGSRHPRSHDEDRA 344
Query: 339 QSSHYGQMDRKGQCYHYDQTNR-QGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQ 397
H R+ H + ++R Q SH + G+ G + D S H T R
Sbjct: 345 SHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRH-SATGRG 403
Query: 398 DQSS------HYGQTERQGQSS--HYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNS 449
SS H G + Q S H D Q H G+ + QS R G+ S
Sbjct: 404 QASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGH-GKAGLRQQSHQESTRGRSGERS 462
Query: 450 HYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQG--QSSHYGKIDRQDQSYHYGQPDGQGQ 507
R G S + T Q S+H G Q SH+ + +D S H +GQ
Sbjct: 463 -----GRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQ--ARDSSRHSASQEGQDT 515
Query: 508 SSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS-SHYGQTDRQGQS-SHYGQTDRQ 565
+ + R G RQG S H ++R G S SH+ T QG+S + +GQ+
Sbjct: 516 IRGHPGSSRGG---------RQG-SHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQS--- 562
Query: 566 GQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPG 625
G S Q++ E G G+ +S + S S Q+ G
Sbjct: 563 ------------GSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSG 610
Query: 626 QEGYQNQGQGFQSRDSQQNGH----QVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQS 681
+NQG S+DS GH + W HH + +Q R R
Sbjct: 611 PRTSRNQGSSV-SQDSDSQGHSEDSERWSGSASRNHHG----SAQEQSRDGSRHPRSHHE 665
Query: 682 CSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQ 741
+ GH +R+S G H G SHE G + H+ +
Sbjct: 666 DRAGHGHSADSSRKS---GTRHTQNSSSGQAA---SSHEQARSSAGERHGSRHQLQSADS 719
Query: 742 RRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQ 783
R T + S RD H Q D + H ++ + Q
Sbjct: 720 SRHSGTGHGQASSAVRD-SGHRGSSGSQATDSEGHSEDSDTQ 760
Score = 150 bits (380), Expect = 3e-36
Identities = 177/729 (24%), Positives = 275/729 (37%), Gaps = 72/729 (9%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHS-QPERQDGDSH 145
H D++ H G S+ G Q G +H + H+E+R + HS RQ G H
Sbjct: 306 HSEDSERHSGSASRNHHGSAWEQS-----RDGSRHPRSHDEDRASHGHSADSSRQSGTRH 360
Query: 146 HGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSER-QDKDFSFDQSERQSQDS 204
R S H Q+ + H S ++ S H+ + R Q D+ R S S
Sbjct: 361 AETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS 420
Query: 205 SSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQS-ERHTQQSETLGQASHFNQTN 263
+ H S GH A R ++ Q+S G+S ER + +L Q S T+
Sbjct: 421 QASDSEGHSENSDTQSVSGHGKAGLR-QQSHQESTRGRSGERSGRSGSSLYQVS----TH 475
Query: 264 QQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQG-QSSHYSQT 322
+Q ++ G G + S H + QD + + R G Q SH+ Q+
Sbjct: 476 EQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQS 535
Query: 323 -DRQGQS-SHYSQPDRQGQS-SHYGQMDRKGQCYHYDQTNRQGQGSHYS-----QPNRQG 374
+R G S SH+S QG+S + +GQ + + G G+ +S + + Q
Sbjct: 536 VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQA 595
Query: 375 QSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQG 434
SS + Q Q QSS +T R SS ++ QG S + +H+G Q
Sbjct: 596 DSSRHSQVG-QGQSSG-PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653
Query: 435 QS------SHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQ---SS 485
+ SH+ DR G + + G + Q SSH G+ S
Sbjct: 654 RDGSRHPRSHH--EDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSR 711
Query: 486 HYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSS--HYSQMDRQGQ 543
H ++ D S H G GQ S+ S H G Q S H D Q
Sbjct: 712 H--QLQSADSSRHSGTGHGQASSA-------VRDSGHRGSSGSQATDSEGHSEDSDTQSV 762
Query: 544 SSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEG 603
S H GQ+ H+ Q+ ++ G+ R+ S Y S + + + + + G
Sbjct: 763 SGH-------GQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTG 815
Query: 604 TRKASYVEQSGRSGRLSQQTPGQEGYQ-NQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKL 662
R+ S+ EQ+ + R S GQ+ + + G + R + V HH H
Sbjct: 816 VRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSH-- 873
Query: 663 LAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQ-SHGEGLSHWAEEEQGHQTWDRHSHES 721
Q R +G+ +S + Q+R S G H E H RH S
Sbjct: 874 --TTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRH--HEASSHADISRH---S 926
Query: 722 QEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQR------RDRQTHEDKQNR--QRRDR 773
Q G ++ RT + + + +D + H + +R R+ + +Q+R R R
Sbjct: 927 QAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPR 986
Query: 774 QTHEDEQNH 782
HED H
Sbjct: 987 SHHEDRAGH 995
Score = 149 bits (375), Expect = 1e-35
Identities = 203/795 (25%), Positives = 294/795 (36%), Gaps = 131/795 (16%)
Query: 81 LVQACYHKLDNKSHGGRTSQQERGQEG-----AQDCKFPG------NTGRQHRQRHEEER 129
L Q H+ + +HG RT G++G A+D +T R H R
Sbjct: 469 LYQVSTHEQPDSAHG-RTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGR 527
Query: 130 QNSHHSQPERQDGDS--HHGQPERQDR-DSHHGQSEKQDRDSHHSQPERQDRDSHHNQSE 186
Q SHH Q + G S HH Q R D+ HGQS + S ++ E Q D +
Sbjct: 528 QGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSA-SRQTRNEEQSGDGTRHSGS 586
Query: 187 RQDKDFSFDQSERQSQ---DSSSGKKVSHK---STSGQAKWQGHIFALNRCEKPIQDSHY 240
R + S S R SQ SSG + S S S + QGH R +H+
Sbjct: 587 RHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHH 646
Query: 241 GQSERHTQQSETLGQASHFNQT-------NQQKSGSYCGQSERLGQELGCGQTDRQGQSS 293
G ++ ++ ++ H ++ + +KSG+ Q+ GQ + R
Sbjct: 647 GSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGE 706
Query: 294 HYG---QTDRQDQSYHYGQTDRQGQSS-------------------HYSQTDRQ-----G 326
+G Q D S H G Q S+ H +D Q G
Sbjct: 707 RHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHG 766
Query: 327 QSSHYSQPDRQGQSSHYGQMDRKGQCYHYD-QTNRQGQGSH-YSQPN---RQGQSSHYGQ 381
Q+ H+ Q ++ G+ R+ + Y T++Q + SH ++ P+ RQG SH+ Q
Sbjct: 767 QAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQG--SHHEQ 824
Query: 382 PDTQDQSSHYGQTDRQDQ-SSHYGQTERQGQSSHYSQ-MDRQGQ-GSHYGQTDRQGQSSH 438
+D S H D QD H G + R Q SH+ Q +DR G GSH+ T QG+S
Sbjct: 825 --ARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSD- 881
Query: 439 YGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYH 498
+ G S +T R + S G R S H+ ++S + I R Q+
Sbjct: 882 -ASRGQSGSRSA-SRTTRNEEQSRDGS--RHSGSRHH-------EASSHADISRHSQA-- 928
Query: 499 YGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQS-- 556
GQGQS + RQG S D +G S + +H G Q +
Sbjct: 929 -----GQGQSEGSRTSRRQGSSVSQDS-DSEGHSEDSERWSGSASRNHRGSAQEQSRHGS 982
Query: 557 ----SHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQ 612
SH+ DR G H + RQ + H S G+ ++ + + G R S +Q
Sbjct: 983 RHPRSHH--EDRAGHG-HSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQ 1039
Query: 613 SGRSGRLSQQTPGQEGYQNQGQG-FQSRDSQQNGHQVWEPEEDSQ----HHQHKLLAQIQ 667
S S R S Q + G + S SQ + + E D+Q H Q Q
Sbjct: 1040 SADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSH 1099
Query: 668 QERPLCHKGRDWQSCSS-------EQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHE 720
QE RDW S Q Q+ +HG + + H R S
Sbjct: 1100 QE-----SARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 1154
Query: 721 SQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRR----DRQTHEDKQNR-------- 768
G R H +R RQ HEQS R +H Q R
Sbjct: 1155 HSASQEGQDTIRAH---PGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQS 1211
Query: 769 --QRRDRQTHEDEQN 781
+ RQT +D+Q+
Sbjct: 1212 GSRSASRQTRKDKQS 1226
Score = 147 bits (371), Expect = 4e-35
Identities = 192/782 (24%), Positives = 285/782 (36%), Gaps = 135/782 (17%)
Query: 86 YHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS- 144
+H+ +++ R SQ +GQ P + Q ++ H ER G +
Sbjct: 588 HHEASSQADSSRHSQVGQGQSSG-----PRTSRNQGSSVSQDSDSQGHSEDSERWSGSAS 642
Query: 145 --HHGQPERQDRD-SHHGQSEKQDRDSH-HSQPERQDRDSHHNQSERQDKDFSFDQSER- 199
HHG + Q RD S H +S +DR H HS + + H Q+ + S + R
Sbjct: 643 RNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARS 702
Query: 200 ------------QSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT 247
QS DSS H S + GH + S SE H+
Sbjct: 703 SAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGH--------RGSSGSQATDSEGHS 754
Query: 248 QQSETL-----GQASHFNQTNQQKSGSYCGQ-SERLGQELGCGQTDRQGQSSHYGQTDRQ 301
+ S+T GQA H Q++Q+ + G+ S R G L T +Q +SSH G T
Sbjct: 755 EDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSH-GWT--- 810
Query: 302 DQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQ-SSHYGQMDRKGQCYHYDQT-N 359
G + Q SH+ Q + S H + D Q H G R Q H++Q+ +
Sbjct: 811 ------GPSTGVRQGSHHEQA--RDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVD 862
Query: 360 RQGQ-GSHYSQPNRQGQS-SHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSH--Y 415
R G GSH+S QG+S + GQ ++ S ++ S + + SSH
Sbjct: 863 RSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADI 922
Query: 416 SQMDRQGQGSHYG-QTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSH 474
S+ + GQG G +T R+ SS D +G + + +H G Q QS H
Sbjct: 923 SRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSA--QEQSRH 980
Query: 475 YSQPDKQGQSSHYGKIDRQDQSYHYGQPD------GQGQSSH----------YGQTDRQG 518
S+ + G D S G P GQ SSH +G +Q
Sbjct: 981 GSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQS 1040
Query: 519 --QSFHYGQPDRQGQSS-----HYSQMDRQGQSS--HYGQTDRQGQSSHYGQTDRQGQSY 569
S H G P RQ S+ H+ Q S H ++D Q S H GQ QS+
Sbjct: 1041 ADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGH-GQDGPHQQSH 1099
Query: 570 HYGQTD----RQGQSSHYIQSQTGEIQGQNKY--FQGTEGTRKASYVEQSGRSGRLSQQT 623
D R G+S +I + Q ++ + + + G R+ S+ EQ+ S R S
Sbjct: 1100 QESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ 1159
Query: 624 PGQEGYQ-NQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSC 682
GQ+ + + G R + V HH H
Sbjct: 1160 EGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSH---------------------- 1197
Query: 683 SSEQGHRQA------------QTR--QSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGT 728
++ QG A QTR + G+G H +W S SQ G +
Sbjct: 1198 TTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQS 1257
Query: 729 QDRRTHKDEQNHQRRDRQTHEHEQSHQRRD---RQTHEDKQNRQRRDRQTH-----EDEQ 780
RT + + + +D + H +R + H Q RD H ED
Sbjct: 1258 SGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRA 1317
Query: 781 NH 782
+H
Sbjct: 1318 SH 1319
Score = 146 bits (368), Expect = 8e-35
Identities = 184/755 (24%), Positives = 283/755 (37%), Gaps = 113/755 (14%)
Query: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPER 151
+S G RTS+ RG +QD G++ R+ R + +Q + +DG S H +
Sbjct: 2229 QSSGPRTSRP-RGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDG-SRHPRSHH 2286
Query: 152 QDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
+DR H H + +HH++ + + ++ R +QS DSS +
Sbjct: 2287 EDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2346
Query: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQTNQQ 265
H S + GH + S SE H++ S+T GQA Q++Q+
Sbjct: 2347 GHGQASSAVRDSGH--------RGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 2398
Query: 266 KS-GSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDR 324
+ G G+S R G L T Q +S+H G+T G +Q + S T +
Sbjct: 2399 STRGRSAGRSGRSGSFLYQVSTHEQSESAH-GRTGTSTGG-RQGSHHKQARDSSRHSTSQ 2456
Query: 325 QGQSSHYSQPDRQG---QSSHYGQM-DRKGQC-YHYDQTNRQGQ--GSHYSQPNRQGQSS 377
+GQ + + P Q SHY Q+ DR G H+ T QG+ SH +R
Sbjct: 2457 EGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQ 2516
Query: 378 HYGQPDTQDQSSHYGQ-----TDRQDQSSH----YGQTE-----RQGQSSHYSQMDRQGQ 423
+ D S H G + R D S H GQ+E R SS D QG
Sbjct: 2517 TRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGH 2576
Query: 424 GSHYGQTDRQGQSSHYG----------------QPDRQGQNSHYGQTDRQGQSSHYGQTD 467
+ +H+G Q DR G + H + RQ + H QT
Sbjct: 2577 SEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAG-HGHSADSSRQSGTRH-TQTS 2634
Query: 468 RQGQSSHYSQPDKQGQSSHYGKIDRQ--DQSYHYGQPDGQGQSS---------------- 509
GQ++ + + +G +Q D S H G GQ S+
Sbjct: 2635 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 2694
Query: 510 ---HYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSS-HYG------QTDRQGQSSHY 559
H +D Q S H GQ QS S R G++S H G T Q +SSH
Sbjct: 2695 NEGHSEDSDTQSVSAH-GQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSH- 2752
Query: 560 GQTDRQGQSYHYGQTDRQGQSSHYIQSQTGE--IQGQ-NKYFQGTEGTRKASYVEQSGRS 616
G T + + ++ SS + SQ G+ I+G G +G V+ SG S
Sbjct: 2753 GWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS 2812
Query: 617 GR---------LSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQ 667
G S + GQ G ++ + ++ + +G + S+HH+ A I
Sbjct: 2813 GSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSR----HSGSRHHEASTHADIS 2868
Query: 668 QERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCG 727
+ + S QG +Q S EG S +E G + + H ++ G
Sbjct: 2869 RHSQAVQGQSEGSRRSRRQGSSVSQ--DSDSEGHSEDSERWSGSASRNHHGSAQEQLRDG 2926
Query: 728 TQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTH 762
++ R+H++ DR H H R+ H
Sbjct: 2927 SRHPRSHQE-------DRAGHGHSADSSRQSGTRH 2954
Score = 144 bits (363), Expect = 3e-34
Identities = 170/745 (22%), Positives = 269/745 (36%), Gaps = 87/745 (11%)
Query: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPER 151
+S G RTS+ + G +QD ++ R R + S+ + +DG H G +
Sbjct: 1256 QSSGSRTSRHQ-GSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGF-HQ 1313
Query: 152 QDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
+DR SH H + +HH++ + ++ R +QS DSS +
Sbjct: 1314 EDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI 1373
Query: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQTNQQ 265
H+ S + GH + S SE H++ S+T GQA Q++++
Sbjct: 1374 GHRQASSAVRDSGH--------RGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKE 1425
Query: 266 KSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQ 325
+ G+S + + + S +GQT G Q ++S +
Sbjct: 1426 SARGQSGESSGRSRSFLYQVSSHEQSESTHGQT-APSTGGRQGSRHEQARNSSRHSASQD 1484
Query: 326 GQSSHYSQP-----DRQGQSSHYGQMDRKGQC-YHYDQTNRQGQGSHYSQPNRQGQSSHY 379
GQ + P RQG S H +DR G YH+ T QG+ + + G S
Sbjct: 1485 GQDTIRGHPGSSRGGRQG-SYHEQSVDRSGHSGYHHSHTTPQGRSD--ASHGQSGPRSAS 1541
Query: 380 GQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYG-QTDRQGQSSH 438
Q ++QS G R S H+ + R G S H + GQG G +T R+ SS
Sbjct: 1542 RQTRNEEQS---GDGSRHSGSRHHEPSTRAGSSRH----SQVGQGESAGSKTSRRQGSSV 1594
Query: 439 YGQPDRQGQNSHYGQTDRQGQSSHYG---QTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQ 495
D +G + + +HYG + R G + S + + H + RQ
Sbjct: 1595 SQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSG 1654
Query: 496 SYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQ 555
+ H G +S Q H + + SS S R+ SS G + +G
Sbjct: 1655 TRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGS 1714
Query: 556 S--------SHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYF--------- 598
S H ++D Q S H Q + Q+GE G++ F
Sbjct: 1715 SGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQ 1774
Query: 599 --------QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWE 650
+ G R+ S EQ+ S R S GQ+ +G SR +Q H +E
Sbjct: 1775 SESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTI--RGHPGSSRGGRQGSH--YE 1830
Query: 651 PEEDS-----QHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWA 705
DS HH H QER +G+ S RQ + + G+G H
Sbjct: 1831 QSVDSSGHSGSHHSH----TTSQERSDVSRGQS----GSRSVSRQTRNEKQSGDGSRHSG 1882
Query: 706 EEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTH--- 762
+ S SQ G + RT +++ + +D + H + +R
Sbjct: 1883 SRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 1942
Query: 763 -----EDKQNRQRRDRQTHEDEQNH 782
E ++ R HED H
Sbjct: 1943 LGSAWEQSRDGSRHPGSHHEDRAGH 1967
Score = 142 bits (358), Expect = 1e-33
Identities = 175/748 (23%), Positives = 283/748 (37%), Gaps = 88/748 (11%)
Query: 89 LDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQ 148
+ +S G R S+++ G +QD G++ R R + +Q + +DG S H +
Sbjct: 2874 VQGQSEGSRRSRRQ-GSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDG-SRHPR 2931
Query: 149 PERQDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSG 207
++DR H H + + H+Q + + ++ R +QS DSS
Sbjct: 2932 SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH 2991
Query: 208 KKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQT 262
+ H S + GH + S +E H++ S+T GQA Q+
Sbjct: 2992 SGIGHGQASSAVRDSGH--------RGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS 3043
Query: 263 NQQKSGSYCGQ-SERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQ 321
+Q+ + G+ S G L T Q +SSH G T + RQG +Q
Sbjct: 3044 HQESARGRSGETSGHSGSFLYQVSTHEQSESSH-GWTGPSTRG-------RQGSRHEQAQ 3095
Query: 322 TDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQT--NRQGQGSHYSQPNRQGQS-SH 378
+ +S Y Q +G H G Q YH++ + + GSH+S QG+S +
Sbjct: 3096 DSSRHSASQYGQDTIRG---HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 3152
Query: 379 YGQPDTQDQS------SHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432
GQ ++ S G + R S H+ + S H + Q +GS ++ R
Sbjct: 3153 RGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSR--RSRR 3210
Query: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQ-SSHYSQPDKQGQSSHYGKID 491
QG SS D +G + + +H G Q + S + + + ++ H D
Sbjct: 3211 QG-SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSAD 3269
Query: 492 RQDQS---YHYGQPDGQGQSSH----------YGQTDRQG--QSFHYGQPDRQGQSS--- 533
R QS + GQ SSH +G +Q S H G P Q S+
Sbjct: 3270 RSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRD 3329
Query: 534 --HYSQMDRQGQSS--HYGQTDRQGQSSHYGQTDRQGQSYHYGQTD----RQGQSSHYIQ 585
H+ Q S H ++D Q S H GQ QS+ D R G+S ++
Sbjct: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGH-GQAGPHQQSHQESARDRSGGRSGRSGSFLY 3388
Query: 586 SQTGEIQGQNKY--FQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQ 643
+ Q ++ + + + G R+ S+ EQ+ S R S GQ+ +G SR +Q
Sbjct: 3389 QVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI--RGHPGSSRRGRQ 3446
Query: 644 NGH---QVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEG 700
H V HH H Q R +G+ S RQ + + G+G
Sbjct: 3447 GSHYEQSVDRSGHSGSHHSH----TTSQGRSDASRGQS----GSRSASRQTRNDEQSGDG 3498
Query: 701 LSH-WAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQR--- 756
H W+ + D H SQ G + RT +++ + +D + H + +R
Sbjct: 3499 SRHSWSHHHEASTQADSSRH-SQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 3557
Query: 757 RDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
+ H Q RD H + R
Sbjct: 3558 SASRNHRGSAQEQSRDGSRHPTSHHEDR 3585
Score = 139 bits (350), Expect = 1e-32
Identities = 199/806 (24%), Positives = 300/806 (37%), Gaps = 143/806 (17%)
Query: 86 YHKLDNKSHGGRTSQQERGQ-EGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS 144
+H+ + R SQ +GQ EG++ + G++ Q + H ER G +
Sbjct: 2858 HHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQ------DSDSEGHSEDSERWSGSA 2911
Query: 145 ---HHGQPERQDRD-SHHGQSEKQDRDSH-HSQPERQDRDSHHNQSERQDKDFSFDQSER 199
HHG + Q RD S H +S ++DR H HS + + H Q+ + S + R
Sbjct: 2912 SRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2971
Query: 200 ------------QSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT 247
QS DSS + H S + GH + S +E H+
Sbjct: 2972 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH--------RGYSGSQASDNEGHS 3023
Query: 248 QQSETL-----GQASHFNQTNQQKSGSYCGQ-SERLGQELGCGQTDRQGQSSH--YGQTD 299
+ S+T GQA Q++Q+ + G+ S G L T Q +SSH G +
Sbjct: 3024 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
Query: 300 R----------QDQSYH----YGQTDRQGQSS----------HYSQTDRQGQS-SHYSQP 334
R QD S H YGQ +G H D G S SH+S
Sbjct: 3084 RGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 3143
Query: 335 DRQGQS-SHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSH----------YGQPD 383
QG+S + GQ + + G S +S S+H GQ +
Sbjct: 3144 TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSE 3203
Query: 384 TQDQSSHYGQTDRQDQSS--HYGQTERQGQSS---HYSQMDRQGQ-GSHYGQTDRQGQSS 437
+S G + QD S H +ER S+ H + Q + GS + ++ + ++
Sbjct: 3204 GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAG 3263
Query: 438 HYGQPDRQGQN-SHYGQTDRQGQ--SSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQD 494
H DR Q+ + + +T GQ SSH G+ H S+ + SS + I R
Sbjct: 3264 HGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGER-HGSRHQQSADSSRHSGIPRGQ 3322
Query: 495 ------QSYHYGQPDGQGQSS--HYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSH 546
S H+G Q S H ++D Q S H GQ QS S DR G
Sbjct: 3323 ASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGH-GQAGPHQQSHQESARDRSG---- 3377
Query: 547 YGQTDRQGQSSHYGQTDRQGQSYHYGQTD-----RQGQ-------SSHYIQSQTGE--IQ 592
G++ R G + T Q +S H G+T RQG SS + SQ G+ I+
Sbjct: 3378 -GRSGRSGSFLYQVSTHEQSESAH-GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIR 3435
Query: 593 GQ-NKYFQGTEGTRKASYVEQSGRSGRLSQQTP---------GQEGYQNQGQGFQSRDSQ 642
G +G +G+ V++SG SG T GQ G ++ + Q+R+ +
Sbjct: 3436 GHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASR--QTRNDE 3493
Query: 643 QNG---------HQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQT 693
Q+G H + DS H Q R ++G S QGH +
Sbjct: 3494 QSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE 3553
Query: 694 RQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQS 753
R S +H ++ + RH E G H E + R TH E S
Sbjct: 3554 RWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAG----HGHSAESS---RQSGTHHAENS 3606
Query: 754 HQRRDRQTHEDKQNRQRRDRQTHEDE 779
+ +HE ++ +H +
Sbjct: 3607 SGGQAASSHEQARSSAGERHGSHHQQ 3632
Score = 134 bits (338), Expect = 2e-31
Identities = 168/723 (23%), Positives = 255/723 (35%), Gaps = 78/723 (10%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHH 146
H D++ G S+ RG Q + R R HE+ + H + RQ G H
Sbjct: 3224 HSEDSERWSGSASRNHRGSVQEQS----RHGSRHPRSHHEDRAGHGHSADRSRQSGTRHA 3279
Query: 147 GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSER-QDKDFSFDQSERQSQDSS 205
S H Q+ + H S+ ++ S H+ R Q D S S
Sbjct: 3280 ETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQ 3339
Query: 206 SGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQS-ERHTQQSETLGQASHFNQTNQ 264
+ H S GH A P Q SH + +R +S G + T++
Sbjct: 3340 ASDSEGHSEESDTQSVSGHGQA-----GPHQQSHQESARDRSGGRSGRSGSFLYQVSTHE 3394
Query: 265 QKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSY-HYGQTDRQGQSSHYSQT- 322
Q ++ G+ G + S H + QD H G + R Q SHY Q+
Sbjct: 3395 QSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSV 3454
Query: 323 DRQGQS-SHYSQPDRQGQS-SHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYG 380
DR G S SH+S QG+S + GQ + + G GS +S SH+
Sbjct: 3455 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW-------SHHH 3507
Query: 381 QPDTQDQSSHYGQ----------TDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQT 430
+ TQ SS + Q T R SS ++ QG S + +H G
Sbjct: 3508 EASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSA 3567
Query: 431 DRQGQ------SSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQS 484
Q + +SH+ DR G + H ++ RQ +H+ + GQ++ + +
Sbjct: 3568 QEQSRDGSRHPTSHH--EDRAG-HGHSAESSRQS-GTHHAENSSGGQAASSHEQARSSAG 3623
Query: 485 SHYGKIDRQ--DQSYHYGQPDGQGQSS-----HYGQTDRQGQSFHYGQPDRQGQSSHYSQ 537
+G +Q D S H G GQ S+ H G + Q D QS
Sbjct: 3624 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 3683
Query: 538 MDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKY 597
Q SH Q +G+S+ G++ R G + T Q +S+H + G G
Sbjct: 3684 QAGPHQQSH--QESTRGRSA--GRSGRSGSFLYQVSTHEQSESAH---GRAGPSTG---- 3732
Query: 598 FQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQ-GQGFQSRDSQQNGHQVWEPEEDSQ 656
G +G+R EQ+ S R S GQ+ + G R + V
Sbjct: 3733 --GRQGSRH----EQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGS 3786
Query: 657 HHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDR 716
HH H Q R G+ S R+ + + G+G H T
Sbjct: 3787 HHSHTT----SQGRSDASHGQS----GSRSASRETRNEEQSGDGSRHSGSRHHEASTQAD 3838
Query: 717 HSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDR---QTHEDKQNRQRRDR 773
S SQ G + R + + + +D + + + +RR + H Q RD
Sbjct: 3839 SSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDG 3898
Query: 774 QTH 776
H
Sbjct: 3899 SRH 3901
Score = 131 bits (330), Expect = 2e-30
Identities = 193/823 (23%), Positives = 309/823 (37%), Gaps = 153/823 (18%)
Query: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPER 151
+S G RTS+++ G +QD G++ R R + +Q + + G S H +
Sbjct: 932 QSEGSRTSRRQ-GSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHG-SRHPRSHH 989
Query: 152 QDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
+DR H H + + H++ + + ++ R +QS DSS +
Sbjct: 990 EDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGI 1049
Query: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQTNQQ 265
+ S + GH + S SE H+++S+T GQ Q++Q+
Sbjct: 1050 PRRQASSAVRDSGHWGS--------SGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQE 1101
Query: 266 KSGSYC-GQSERLGQELGCGQTDRQGQSSH---YGQTDRQDQSYHYGQTD---------- 311
+ + G+S R G + T Q +S+H T R+ S+H D
Sbjct: 1102 SARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEG 1161
Query: 312 ----------RQG--QSSHYSQT-DRQGQS-SHYSQPDRQGQS-SHYGQMDRKGQCYHYD 356
R+G Q SH+ Q+ DR G S SH+S QG+S + +GQ +
Sbjct: 1162 QDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 1221
Query: 357 QTNRQGQGSHYS----------------------QPNRQGQSSHYGQPDTQDQSS----- 389
+ + G GS +S Q + S H G +QD S
Sbjct: 1222 KDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSD 1281
Query: 390 ------------HYGQTDRQ--DQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQ 435
H+G + Q D S H G + S +S + G+H+ ++ GQ
Sbjct: 1282 DSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQ 1341
Query: 436 --SSH----------YGQPDRQGQNS--HYGQTDRQGQSS-----HYGQTDRQGQSS--H 474
SSH +G +Q +S H G RQ S+ H G + Q +S H
Sbjct: 1342 AVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGH 1401
Query: 475 YSQPDKQGQSSHYGKIDRQDQSY------HYGQPDGQGQSSHYGQTDRQGQSFHYGQP-- 526
D Q S+H G+ QS+ G+ G+ +S Y + + +GQ
Sbjct: 1402 SEDSDTQSVSAH-GQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAP 1460
Query: 527 ---DRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHY 583
RQG ++ + +S GQ +G + RQG SYH DR G S ++
Sbjct: 1461 STGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGS-SRGGRQG-SYHEQSVDRSGHSGYH 1518
Query: 584 IQSQTGEIQGQNKYFQGTEGTRKAS----YVEQSGRSGRLS---------QQTPGQEGYQ 630
T QG++ G G R AS EQSG R S + +
Sbjct: 1519 HSHTTP--QGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQV 1576
Query: 631 NQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQ 690
QG+ S+ S++ G V + DS+ H ER R+ + EQ
Sbjct: 1577 GQGESAGSKTSRRQGSSV-SQDRDSEGHSE------DSERRSESASRNHYGSAREQSRHG 1629
Query: 691 AQTRQSHGEG-LSHWAEEEQGHQTWDRHSHESQEG-PCGTQDRRTHKDEQNHQRRDRQTH 748
++ +SH E SH E Q+ RH+ S G +Q++ + H R +Q+
Sbjct: 1630 SRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSA 1689
Query: 749 EHEQ---SHQRRDRQTHEDKQNR-----QRRDRQTHEDEQNHQ 783
+ + +R+D D NR Q D + H +E + Q
Sbjct: 1690 DSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQ 1732
Score = 131 bits (329), Expect = 3e-30
Identities = 175/756 (23%), Positives = 282/756 (37%), Gaps = 95/756 (12%)
Query: 86 YHKLDNKSHGGRTSQQERGQ-EGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS 144
+H+ + R SQ +GQ EG++ + G++ Q + H ER G +
Sbjct: 3182 HHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQ------DSDSEGHSEDSERWSGSA 3235
Query: 145 ---HHGQPERQDRD-SHHGQSEKQDRDSH-HSQPERQDRDSHHNQSERQDKDFSFDQSER 199
H G + Q R S H +S +DR H HS + + H ++ + S + R
Sbjct: 3236 SRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQAR 3295
Query: 200 QSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDS-HYGQS-------ERHTQQSE 251
S G + H+ ++ ++ G + ++DS H+G S E H+++S+
Sbjct: 3296 SSPGERHGSR--HQQSADSSRHSG--IPRGQASSAVRDSRHWGSSGSQASDSEGHSEESD 3351
Query: 252 TL-----GQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYH 306
T GQA Q++Q+ + G G++ R G + T Q +S H
Sbjct: 3352 TQSVSGHGQAGPHQQSHQESARDRSG-----------GRSGRSGSFLYQVSTHEQSESAH 3400
Query: 307 YGQTDRQG--QSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQT-NRQGQ 363
G Q SH+ Q R SQ + H G R Q HY+Q+ +R G
Sbjct: 3401 GRTRTSTGRRQGSHHEQA-RDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGH 3459
Query: 364 -GSHYSQPNRQGQS-SHYGQPDTQDQSSHYGQTDRQDQS--------SHYGQTERQGQSS 413
GSH+S QG+S + GQ ++ S QT +QS SH+ + Q SS
Sbjct: 3460 SGSHHSHTTSQGRSDASRGQSGSRSASR---QTRNDEQSGDGSRHSWSHHHEASTQADSS 3516
Query: 414 HYSQMDRQGQGSHYGQTDRQGQSSHYGQP-DRQGQNSHYGQTDRQGQSSHYG---QTDRQ 469
+SQ GQG G + Q S Q D QG + + +H G + R
Sbjct: 3517 RHSQ---SGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRD 3573
Query: 470 GQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQ 529
G S + + H + RQ ++H G +S + Q H +
Sbjct: 3574 GSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQS 3633
Query: 530 GQSSHYSQMDRQGQSS------HYGQTDRQGQSS--HYGQTDRQGQSYHYGQTDRQGQSS 581
SS +S + SS H G + Q S H +D Q S H GQ+
Sbjct: 3634 ADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAH-------GQAG 3686
Query: 582 HYIQSQTGEIQGQNKYFQGTEGT---RKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQS 638
+ QS +G++ G G+ + +++ + GR T G++G +++ S
Sbjct: 3687 PHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSS 3746
Query: 639 RDS-QQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSH 697
R S Q G S+ + Q H G S ++ QG A QS
Sbjct: 3747 RHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSH-HSHTTSQGRSDASHGQSG 3805
Query: 698 GEGLSHWAEEEQGHQTWDRHS----HESQEGPCGTQDRRTHKDEQNHQRRDR-------Q 746
S E+ RHS HE+ ++ ++ + E RR R Q
Sbjct: 3806 SRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQ 3865
Query: 747 THEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNH 782
+ E + +R++ +N R+ D H
Sbjct: 3866 DSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRH 3901
Score = 129 bits (323), Expect = 1e-29
Identities = 184/776 (23%), Positives = 275/776 (35%), Gaps = 137/776 (17%)
Query: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQN-----------SHHSQPERQ 140
+ H G + +G Q G++G H +ER + S ++ E+Q
Sbjct: 1814 RGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQ 1873
Query: 141 DGDS-------HHGQPERQDRDSH----HGQSEKQDRDSHHSQPERQDRDS--HHNQSER 187
GD HH R D H GQS + QD DS H SER
Sbjct: 1874 SGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSER 1933
Query: 188 QDKDFS---FDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSE 244
S + QS+D S H+ +G GH DS
Sbjct: 1934 WSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGH----GHS----------ADSSRQSGT 1979
Query: 245 RHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQS 304
RHT+ S GQA+ ++ +++ S G+ +L + R H + S
Sbjct: 1980 RHTESSSR-GQAA----SSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDS 2034
Query: 305 YHYGQTDRQGQSS--HYSQTD-----RQGQSSHYSQPDRQGQSSHYGQMD-RKGQCYHYD 356
H G + Q S H +D QG++ + Q ++ G+ R G +
Sbjct: 2035 GHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQV 2094
Query: 357 QTNRQGQGSH-YSQPNRQG-QSSHYGQPDTQDQSSHYGQTDRQDQ-SSHYGQTERQGQSS 413
T+ Q + +H S P+ G Q SHY Q QD S H + QD H G + Q S
Sbjct: 2095 STHEQSESTHGQSAPSTGGRQGSHYDQ--AQDSSRHSASQEGQDTIRGHPGPSRGGRQGS 2152
Query: 414 HYSQ-MDRQG-QGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQ 471
H Q +DR G GSH+ T QG+S ++ GQ+ + S ++ G
Sbjct: 2153 HQEQSVDRSGHSGSHHSHTTSQGRS-----------DASRGQSGSRSASRKTYDKEQSGD 2201
Query: 472 SSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQ 531
S +S S H+ D S H GQGQSS +T R S D +G
Sbjct: 2202 GSRHS------GSHHHEASSWADSSRH--SLVGQGQSSG-PRTSRPRGSSVSQDSDSEGH 2252
Query: 532 SSHYSQMDRQGQSSHYGQTDRQGQS------SHYGQTDRQGQSYHYGQTDRQGQSSHYIQ 585
S + +H+G Q + SH+ DR G H ++ RQ + H
Sbjct: 2253 SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHH--EDRAGHG-HSAESSRQSGTHHAEN 2309
Query: 586 SQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLS----------------QQTPGQEGY 629
S G+ ++ + + G R S+ +QS S R S + + G +
Sbjct: 2310 SSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQAS 2369
Query: 630 QNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHK------------LLAQIQ-QERPLCHKG 676
++G S + H P + S + L Q+ E+ G
Sbjct: 2370 DSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHG 2429
Query: 677 RDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQ-----DR 731
R S QG Q R S S + ++G T H S G G+ DR
Sbjct: 2430 RTGTSTGGRQGSHHKQARDS-----SRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDR 2484
Query: 732 R----THKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQ 783
+H Q R +H H S + RQT D+Q+ D H ++H+
Sbjct: 2485 SGHSGSHHSHTTSQGRSDASHGHSGS-RSASRQTRNDEQS---GDGSRHSGSRHHE 2536
Score = 128 bits (322), Expect = 2e-29
Identities = 188/778 (24%), Positives = 283/778 (36%), Gaps = 118/778 (15%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHS-QPERQDGDSH 145
H D++ G S+ G Q G +H H E+R HS RQ G H
Sbjct: 1927 HSEDSERWSGSASRNHLGSAWEQS-----RDGSRHPGSHHEDRAGHGHSADSSRQSGTRH 1981
Query: 146 HGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSH------HNQSERQDKDFSF-DQSE 198
R S H Q+ + H S + Q DS H Q+ +D S
Sbjct: 1982 TESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSG 2041
Query: 199 RQSQDSSSGKKVSH-KSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQAS 257
Q+ DS + S +S S Q K P Q SH + Q E+ G++
Sbjct: 2042 SQASDSEGHSEDSDTQSVSAQGK-----------AGPHQQSH--KESARGQSGESSGRSG 2088
Query: 258 HF---NQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQG 314
F T++Q ++ + G G Q S H + QD + R G
Sbjct: 2089 SFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGG 2148
Query: 315 -QSSHYSQT-DRQGQS-SHYSQPDRQGQS----SHYGQMDRKGQCYHYDQT--NRQGQGS 365
Q SH Q+ DR G S SH+S QG+S G + Y +Q+ + GS
Sbjct: 2149 RQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGS 2208
Query: 366 HYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGS 425
H+ + + SS + Q QSS +T R SS ++ +G S + +
Sbjct: 2209 HHHEASSWADSSRHSLVG-QGQSSG-PRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRN 2266
Query: 426 HYGQTDRQGQS------SHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPD 479
H+G Q + SH+ DR G + H ++ RQ +H+ + GQ++ +
Sbjct: 2267 HHGSAQEQSRDGSRHPRSHH--EDRAG-HGHSAESSRQ-SGTHHAENSSGGQAASSHEQA 2322
Query: 480 KQGQSSHYGKIDRQ--DQSYHYGQPDGQGQSS-----HYGQTDRQGQSF--HYGQPDRQG 530
+ +G +Q D S H G GQ S+ H G + Q H D Q
Sbjct: 2323 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQS 2382
Query: 531 QSSH--------YSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQT-----DRQ 577
S+H Q +G+S+ G++ R G + T Q +S H G+T RQ
Sbjct: 2383 VSAHGQAGPHQQSHQESTRGRSA--GRSGRSGSFLYQVSTHEQSESAH-GRTGTSTGGRQ 2439
Query: 578 G-------QSSHYIQSQTGE--IQGQ-NKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQE 627
G SS + SQ G+ I G G +G+ V++SG SG T Q
Sbjct: 2440 GSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQ- 2498
Query: 628 GYQNQGQGF--------QSRDSQQNGHQVWEPEEDSQHHQ---------HKLLAQIQQER 670
G + G Q+R+ +Q+G S+HH+ H + Q Q E
Sbjct: 2499 GRSDASHGHSGSRSASRQTRNDEQSGD--GSRHSGSRHHEASSRADSSGHSQVGQGQSEG 2556
Query: 671 PLCHKGRDWQSC----SSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPC 726
P R+W S S QGH + R S +H ++ + RH QE
Sbjct: 2557 P--RTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQE--- 2611
Query: 727 GTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
DR H + R+ H S + + + + R H+ + R
Sbjct: 2612 ---DRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSR 2666
Score = 125 bits (315), Expect = 1e-28
Identities = 172/740 (23%), Positives = 268/740 (36%), Gaps = 80/740 (10%)
Query: 86 YHKLDNKSHG-----------GRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHH 134
+H+ D SHG T GQ + + + G +H RH++ +S H
Sbjct: 1311 FHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRH 1370
Query: 135 SQPERQDGDS------HHGQPERQ--DRDSHHGQSEKQDRDSH-----HSQPERQDRDSH 181
S + S H G Q + + H S+ Q +H H Q ++
Sbjct: 1371 SGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQ 1430
Query: 182 HNQSERQDKDFSFDQSERQSQDSSSGKKV-SHKSTSGQAKWQGHIFALNRCEKPIQDSHY 240
+S + + F + S + +S+ G+ S G Q + + + QD+
Sbjct: 1431 SGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIR 1490
Query: 241 G---------QSERHTQQSETLGQAS--HFNQTNQQKSGSYCGQSERLGQELGCGQTDRQ 289
G Q H Q + G + H + T Q +S + GQS G QT +
Sbjct: 1491 GHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQS---GPRSASRQTRNE 1547
Query: 290 GQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRK 349
QS G R S H+ + R G S H SQ QG+S+ RQG SS D +
Sbjct: 1548 EQS---GDGSRHSGSRHHEPSTRAGSSRH-SQVG-QGESAGSKTSRRQG-SSVSQDRDSE 1601
Query: 350 GQCYHYDQTNRQGQGSHYSQPNRQGQ-SSHYGQPDTQDQSSHYGQTDRQDQS-SHYGQTE 407
G ++ + +HY Q + S + +D++SH + QS + + +T
Sbjct: 1602 GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETS 1661
Query: 408 RQGQSSHYSQMDRQGQGSHYGQTDRQ-GQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQT 466
GQ++ + R G +G +Q SS R+ +S G + +G S +
Sbjct: 1662 SGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQA-S 1720
Query: 467 DRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQP 526
D +G H + D Q S+H G+ QS+ Q +GQS ++ R G +
Sbjct: 1721 DSEG---HSEESDTQSVSAH-GQAGPHQQSH---QESTRGQSGE--RSGRSGSFLYQVST 1771
Query: 527 DRQGQSSHYSQMDRQGQSSHYGQTDR--QGQSSHYGQTDRQGQSY---HYGQTDRQGQSS 581
Q +S+H R G S+ Q R Q + S ++GQ H G + Q S
Sbjct: 1772 HEQSESAH----GRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGS 1827
Query: 582 HYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDS 641
HY QS + + T R QSG S +S+QT + + G G SR S
Sbjct: 1828 HYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSG-SRSVSRQTRNE---KQSGDG--SRHS 1881
Query: 642 QQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGL 701
H+ DS H Q R ++G S QGH + R S
Sbjct: 1882 GSRHHEA-SSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR 1940
Query: 702 SH----WAEEEQG-HQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQR 756
+H W + G H + G R++ R + HEQ+
Sbjct: 1941 NHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSS 2000
Query: 757 RDRQTHEDKQNRQRRDRQTH 776
+ H Q D H
Sbjct: 2001 AG-ERHGSHHQLQSADSSRH 2019
Score = 124 bits (311), Expect = 3e-28
Identities = 184/777 (23%), Positives = 272/777 (35%), Gaps = 112/777 (14%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEE--ERQNSHHSQPERQDGDS 144
H+ D HG + G H Q ER SHH Q D
Sbjct: 2609 HQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ--SADSSR 2666
Query: 145 H----HGQPERQDRDSHH---GQSEKQDRDSHHSQPERQDRDSH-----HNQSERQDK-- 190
H HGQ RDS H S+ D + H + Q +H H QS ++
Sbjct: 2667 HSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARG 2726
Query: 191 ----------DFSFDQSERQSQDSSSG-KKVSHKSTSGQAKWQGHIFALNRCEKPIQDS- 238
F + S + +SS G S + G Q + + + QD+
Sbjct: 2727 RSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTI 2786
Query: 239 --HYGQS--------ERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDR 288
H G S H+ S + H + T+Q +S + GQS G T
Sbjct: 2787 RGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQS---GSRSASRTTRN 2843
Query: 289 QGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDR 348
+ QS G R S H+ + S +SQ QGQS + RQG SS D
Sbjct: 2844 EEQS---GDGSRHSGSRHH-EASTHADISRHSQA-VQGQSEGSRRSRRQG-SSVSQDSDS 2897
Query: 349 KGQCYHYDQTNRQGQGSHYSQPNRQ-GQSSHYGQPDTQDQSSHYGQTDRQDQS-SHYGQT 406
+G ++ + +H+ Q S + + +D++ H D QS + + QT
Sbjct: 2898 EGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQT 2957
Query: 407 ERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQT 466
GQ++ + R G +G +Q S R H + S H G +
Sbjct: 2958 SSGGQAASSHEQARSSAGERHGSHHQQSADS-----SRHSGIGHGQASSAVRDSGHRGYS 3012
Query: 467 DRQGQSS--HYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYG 524
Q + H D Q S+H G+ QS+ Q +G+S G+T SF Y
Sbjct: 3013 GSQASDNEGHSEDSDTQSVSAH-GQAGSHQQSH---QESARGRS---GETSGHSGSFLYQ 3065
Query: 525 -QPDRQGQSSH----YSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQG---------QSYH 570
Q +SSH S RQG Q + +S YGQ +G Q YH
Sbjct: 3066 VSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYH 3125
Query: 571 YGQT-DRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYV----EQSGRSGRLS----- 620
+ + D G S + T QG++ +G G+R AS EQSG S R S
Sbjct: 3126 HEHSVDSSGHSGSHHSHTTS--QGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHH 3183
Query: 621 ----QQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKG 676
+ QGQ SR S++ G V + DS+ H ER
Sbjct: 3184 EASTHADISRHSQAVQGQSEGSRRSRRQGSSV-SQDSDSEGHSE------DSERWSGSAS 3236
Query: 677 RDWQSCSSEQG-HRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGT--QDRRT 733
R+ + EQ H R H + H ++ Q+ RH+ S G + + R+
Sbjct: 3237 RNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARS 3296
Query: 734 HKDEQNHQRRDRQTHEHEQSHQRRDRQT-------HEDKQNRQRRDRQTHEDEQNHQ 783
E++ R + S R + + H Q D + H +E + Q
Sbjct: 3297 SPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQ 3353
Score = 105 bits (263), Expect = 1e-22
Identities = 124/506 (24%), Positives = 193/506 (38%), Gaps = 55/506 (10%)
Query: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPER 151
+S G RTS+ + G +QD G++ R R + +Q + +DG S H
Sbjct: 3525 QSAGPRTSRNQ-GSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDG-SRHPTSHH 3582
Query: 152 QDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
+DR H H + +HH++ + + ++ R +QS DSS +
Sbjct: 3583 EDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 3642
Query: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQTNQQ 265
H S + GH + S SE H++ S+T GQA Q++Q+
Sbjct: 3643 GHGQASSAVRDSGH--------RGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 3694
Query: 266 KS-GSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDR 324
+ G G+S R G L T Q +S+H G+ G Q + S +
Sbjct: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAH-GRAG-PSTGGRQGSRHEQARDSSRHSASQ 3752
Query: 325 QGQSSHYSQP-----DRQGQSSHYGQMDRKGQC-YHYDQTNRQGQ--GSHYSQPNRQGQS 376
+GQ + P RQG S H +DR G H+ T QG+ SH +R
Sbjct: 3753 EGQDTIRGHPGSRRGGRQG-SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASR 3811
Query: 377 SHYGQPDTQDQSSHYG----QTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432
+ + D S H G + Q SS + Q+ QG+S+ + RQG S +D
Sbjct: 3812 ETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQS-GQGESAGSRRSRRQG-SSVSQDSDS 3869
Query: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQ--SSHYGQTDRQGQSSHYSQPDKQGQSS----- 485
+ + +H+G + Q + S H G + R S S P + S+
Sbjct: 3870 EAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHG 3929
Query: 486 HYGKIDRQDQSYHYG-QPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
H+ + QD +YH G Q G SS S+HY + Q + R G
Sbjct: 3930 HFSSLS-QDSAYHSGIQSRGSPHSS---------SSYHYQSEGTERQKGQSGLVWRHGS- 3978
Query: 545 SHYGQTDRQGQSSHYGQTDRQGQSYH 570
YG D S + + SY+
Sbjct: 3979 --YGSADYDYGESGFRHSQHGSVSYN 4002
Score = 104 bits (260), Expect = 3e-22
Identities = 155/701 (22%), Positives = 249/701 (35%), Gaps = 121/701 (17%)
Query: 81 LVQACYHKLDNKSHGGRTSQQERGQ----EGAQDCKFPG------NTGRQHRQRHEEERQ 130
L Q H+ +HG + R Q E A+D +T R H RQ
Sbjct: 3387 LYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQ 3446
Query: 131 NSHHSQPERQDGDS--HHGQPERQDR-DSHHGQS-----EKQDRDSHHSQPERQDRDSHH 182
SH+ Q + G S HH Q R D+ GQS +Q R+ S + SHH
Sbjct: 3447 GSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHH 3506
Query: 183 NQSERQDKDFSFDQSERQSQDSSSGKKVSH---KSTSGQAKWQGHIFALNRCEKPIQDSH 239
+++ Q QS Q S+G + S S S + QGH R +H
Sbjct: 3507 HEASTQADSSRHSQS---GQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 3563
Query: 240 YGQSERHTQQSETLGQASHFNQT-------NQQKSGSYCGQSERLGQELGCGQTDRQGQS 292
G ++ ++ + H ++ + ++SG++ ++ GQ + R
Sbjct: 3564 RGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAG 3623
Query: 293 SHYGQTDRQ--DQSYHYGQTDRQGQSS-----HYSQTDRQGQSS--HYSQPDRQGQSSH- 342
+G +Q D S H G Q S+ H + Q S H D Q S+H
Sbjct: 3624 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 3683
Query: 343 -----------------YGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQ 385
G+ R G + T+ Q + +H G +
Sbjct: 3684 QAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQAR 3743
Query: 386 DQSSHYGQTDRQDQSSHYGQTERQGQ--SSHYSQMDRQG-QGSHYGQTDRQGQSSHYGQP 442
D S H + QD + + R G+ S H +DR G GSH+ T QG+S
Sbjct: 3744 DSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRS------ 3797
Query: 443 DRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQP 502
++ +GQ+ + S ++ G S +S S H+ + D S H
Sbjct: 3798 -----DASHGQSGSRSASRETRNEEQSGDGSRHS------GSRHHEASTQADSSRH--SQ 3844
Query: 503 DGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQ--SSHYG 560
GQG+S+ ++ RQG S D + + +H+G + Q + S H G
Sbjct: 3845 SGQGESAGSRRSRRQGSSVSQ-DSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPG 3903
Query: 561 QTDRQGQSY--------------HYGQTDRQGQSSHY---IQSQTGEIQGQNKYFQGTEG 603
+ R S+ +G Q S Y IQS+ G + Y +EG
Sbjct: 3904 SSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSR-GSPHSSSSYHYQSEG 3962
Query: 604 TRKASYVEQSGRSGRL--------SQQTPGQEGYQNQGQGFQSRDSQ----QNGHQVWEP 651
T + Q G+SG + + G+ G+++ G S +S + + +
Sbjct: 3963 TER-----QKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKA 4017
Query: 652 EEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQ 692
+ H I ++ LC D S + G Q+Q
Sbjct: 4018 SAFGKDHPRYYATYINKDPGLCGHSSD---ISKQLGFSQSQ 4055
Score = 47.0 bits (110), Expect = 7e-05
Identities = 56/237 (23%), Positives = 87/237 (36%), Gaps = 44/237 (18%)
Query: 86 YHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS- 144
+H+ ++ R SQ +G+ + R RQ + + + PE + S
Sbjct: 3830 HHEASTQADSSRHSQSGQGESAG--------SRRSRRQGSSVSQDSDSEAYPEDSERRSE 3881
Query: 145 -----HHGQPERQDRD-SHHGQSEKQDRDSH-HSQPERQD----RDSHHNQSERQDKDFS 193
HHG Q RD S H S +D SH S P + D ++ H S QD +
Sbjct: 3882 SASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYH 3941
Query: 194 FDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSE-RHTQQSET 252
R S SSS + T Q G ++ D YG+S RH+Q
Sbjct: 3942 SGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSA--DYDYGESGFRHSQHGSV 3999
Query: 253 --------------LGQASHFNQTNQQKSGSY-------CGQSERLGQELGCGQTDR 288
+ +AS F + + + +Y CG S + ++LG Q+ R
Sbjct: 4000 SYNSNPVVFKERSDICKASAFGKDHPRYYATYINKDPGLCGHSSDISKQLGFSQSQR 4056
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 170 bits (431), Expect = 4e-42
Identities = 187/870 (21%), Positives = 345/870 (39%), Gaps = 100/870 (11%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
M+ LL SI + ++F++Y + D A L K++LK LL EFG +L+RP+DP+TV+ IL L
Sbjct: 1 MSPLLRSICDITEIFNQYVSHDCDGAALTKKDLKNLLEREFGAVLRRPHDPKTVDLILEL 60
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDN----------KSHGGRTSQQERGQEGAQ- 109
LD D +G +DF+E+LL +F++ QACY+ L + G + Q+R QE Q
Sbjct: 61 LDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQR 120
Query: 110 -----DCKFPGNTGRQHRQ-RHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEK 163
D + G++ RQ R E+ER+ + + + +R+D + + E
Sbjct: 121 RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEW 180
Query: 164 QDRDSHHSQPERQDRDSHHNQSERQDKD----------FSFDQSERQSQDSSSGKKVSHK 213
Q+R+ ++ E+ H E D++ + E+Q Q +V +
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 214 STSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQ 273
+ +W+ L + E+ +Q+ + ++ E L + +++ Q
Sbjct: 241 EE--EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 274 SERLGQELGCGQTD---------RQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTD- 323
R Q+L Q + R+ Q Q +R++Q Q +R+ Q Q +
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 324 -RQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQP 382
R+ Q + +R+ Q Q R+ Q +Q R+ Q Q R+ Q Q
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 383 DTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQP 442
++Q Q + + + H + ER+ Q Q +R+ +T+R Q Q
Sbjct: 419 LRREQQLRREQEEERHEQKH--EQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Query: 443 DRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQP 502
R + + + + Q +R+ Q Q +++ Q ++ RQ++ Q
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ-----RLKRQEEEERLQQR 531
Query: 503 DGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSH----YGQTDRQGQSSH 558
Q Q +R+ Q + R Q ++ R+ + + +R+ Q
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 559 YGQTDRQGQSYHYGQTDRQGQS-----------------SHYIQSQTGEIQGQNKYFQGT 601
Q +R Q + +R Q ++S+ E + Q + +
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ-LRRE 650
Query: 602 EGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQV--------WEPEE 653
+ R+ +++ RL Q+ + + + Q + +Q ++ W+ E
Sbjct: 651 QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 710
Query: 654 DSQHHQHKLLA----------QIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSH 703
++ Q K+ + + +QE + + Q E+ HRQ Q + +
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
Query: 704 WAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRR------ 757
W EE+ + R S P Q R + E+ QR R E E+ QRR
Sbjct: 771 WQAEEKSERGRQR---LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
Query: 758 --DRQTHEDKQNRQRRDR--QTHEDEQNHQ 783
+ Q E+++ QRR+R Q E+E Q
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
Score = 92.0 bits (227), Expect = 2e-18
Identities = 134/715 (18%), Positives = 272/715 (38%), Gaps = 63/715 (8%)
Query: 100 QQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPE-----RQDR 154
++ R QE + C+ ++ Q EER+ + ERQ + Q E R++
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Query: 155 DSHHGQS-EKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHK 213
+ Q E+Q R+ Q E + + RQ+++ + + E + Q ++ +
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY-REEEELQRQKRKQRYRDE 1217
Query: 214 STSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQ 273
KWQ E ++D+ R +Q L + ++ +QQ G+
Sbjct: 1218 DQRSDLKWQWE----PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273
Query: 274 SERLGQELG---CGQTDR---------QGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQ 321
+ +E Q DR + + + DR+ Q + + + +
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 322 TDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPN----RQGQSS 377
TDR+ + +R+ Q + DRK + ++ Q QG + + RQ +
Sbjct: 1334 TDRKFREEEQLLQEREEQPLRRQERDRK---FREEELRHQEQGRKFLEEEQRLRRQERER 1390
Query: 378 HYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSS 437
+ + + Q + Q RQD+ + + E+Q + R+ + + +R+ +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE-QQVRRQERERKFL 1449
Query: 438 HYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSY 497
Q RQ ++ + + ++ Q Q RQ + + + ++Q + RQ++
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ--------LRRQERDR 1501
Query: 498 HYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSS 557
+ + + + Q + + Q H RQ + + Q ++Q + GQ RQ +
Sbjct: 1502 KFREQELRSQEPERKFLEEE-QQLH-----RQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 558 HYGQTDRQGQSYHYGQTDRQGQSSHY-IQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRS 616
+ + ++ Q Q RQ + + ++ Q Q Q + F E + +Q R
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615
Query: 617 GRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPE----EDSQHHQHKLLAQIQQERPL 672
R + ++ Q + + R + EP+ E Q +H + ++E L
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL 1675
Query: 673 CHKGRDWQSCSSEQGHR----QAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGT 728
+G + Q E+ + + Q R+ E E++ Q +R E ++
Sbjct: 1676 LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ----- 1730
Query: 729 QDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQ 783
+ T +++ Q R R+ E EQ R+ Q + RQ RDR+ E+EQ Q
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQ----QLRRQERDRKFREEEQLRQ 1781
Score = 92.0 bits (227), Expect = 2e-18
Identities = 135/729 (18%), Positives = 288/729 (39%), Gaps = 67/729 (9%)
Query: 97 RTSQQERGQEGAQDCKFPGNTGRQHR-QRHEEERQNSHHS---QPERQDGDSHH-----G 147
R Q++R QE + + RQ R QR+ +E Q S +PE+++ + G
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244
Query: 148 QPERQDRDSHHGQ--SEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSS 205
+ Q R Q + +D H E+Q+RD + Q +D F + E+ ++
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 206 SGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQ 265
K+ + Q + Q + R EK + +++R ++ E L Q +Q
Sbjct: 1305 --KEAKRRDRKSQEEKQ--LLREEREEKRRRQ----ETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 266 KSGSYCGQSERLGQELGCGQTD------RQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHY 319
+ + E QE G + RQ + + + ++Q + Q RQ + +
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
Query: 320 SQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHY 379
+ ++Q + R+ + + +R+ + +Q RQ + + + + Q
Sbjct: 1417 REEEQQLSRQERDRKFRE-EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 380 GQPDTQDQSSHY----GQTDRQDQSSHYGQTERQGQS------SHYSQMDRQGQGSHYGQ 429
Q Q++ + Q RQ++ + + E + Q Q+ RQ + + Q
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
Query: 430 TDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGK 489
++Q + GQ RQ ++ + + ++ Q Q RQ + + ++ K
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ--------K 1587
Query: 490 IDRQDQSYHYGQPDGQ-----GQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQ--G 542
+ RQ+Q + + + Q GQ + DR+ + +R+ Q H + DR+
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 543 QSSHYGQTDRQGQSSH-----YGQTDRQGQSYHYGQTDRQGQSSHYIQS--QTGEIQGQN 595
+ + +R+ Q H + + ++ Q Q RQ + + + Q + +
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 596 KYFQGTEGTRKASYVEQSGRSGRLSQQTPG-----QEGYQNQGQGFQSRDSQQNGHQVWE 650
K+ Q + R+ + +L Q+T QE Y+ + Q R ++ Q+
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE-QQLRR 1766
Query: 651 PEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQ---GHRQAQTRQSHGEGLSHWAEE 707
E D + + + L Q ++E+ L + D + EQ + Q R +G W EE
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 708 EQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQN 767
+ + ++ + ++ +++ +++ + ++ E ++ Q R+R+ E+
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Query: 768 RQRRDRQTH 776
RQ+++ Q H
Sbjct: 1887 RQQKEEQRH 1895
Score = 84.7 bits (208), Expect = 3e-16
Identities = 126/700 (18%), Positives = 273/700 (39%), Gaps = 63/700 (9%)
Query: 86 YHKLDNKSHGGRTSQQER----GQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQD 141
+ +L++ R SQQ+ G++ +D + +Q + EE Q Q E +
Sbjct: 1250 FRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 142 GDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQS 201
D + ++ R+ + +Q+ D + E+ ++ RQ++D F + E +
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
Query: 202 QDSSSGKKVSHKSTSGQAKWQGHIFALN----RCEKPIQDSHYGQSERHTQQSETLGQAS 257
Q+ G+K + + + + F RC++ Q + + ++ + L +
Sbjct: 1370 QEQ--GRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE 1427
Query: 258 H---FNQTNQQ-----KSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQ 309
F + QQ + + + ++L QE R+ + +R++Q H +
Sbjct: 1428 RDRKFREEEQQVRRQERERKFLEEEQQLRQE-----RHRKFREEEQLLQEREEQQLHRQE 1482
Query: 310 TDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQ 369
DR+ Q RQ + + + + + Q ++ + Q +RQ + + Q
Sbjct: 1483 RDRKFLEEE-QQLRRQERDRKFREQELRSQEPERKFLEEE------QQLHRQQRQRKFLQ 1535
Query: 370 PNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHY----SQMDRQGQGS 425
+Q + GQ QD+ + + ++ Q Q RQ + + ++ RQ Q
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 426 HYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSS 485
+ + ++Q + Q RQ ++ + + ++ Q Q RQ + + + + Q +
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
Query: 486 HYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSS 545
+ R D+ + + + Q Q RQ + + + ++Q + + Q +
Sbjct: 1656 EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ- 1714
Query: 546 HYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTR 605
Q RQ + + ++ Q Q RQ + ++ + + + + + E R
Sbjct: 1715 ---QLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 606 KASYVEQSGRSGRLSQQTPGQEG---YQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKL 662
K EQ R R QQ QE ++ + Q Q R+ QQ Q + D ++ +
Sbjct: 1772 KFREEEQL-RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ----QRDGKYRWEEE 1826
Query: 663 LAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQ 722
Q++++ + RD Q + EQ Q ++R+ E W EEEQ + Q
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE---LWQEEEQKRR---------Q 1874
Query: 723 EGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTH 762
E ++R+ ++ Q+++ Q H + ++ + H
Sbjct: 1875 E-----RERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGH 1909
Score = 84.3 bits (207), Expect = 4e-16
Identities = 132/711 (18%), Positives = 276/711 (38%), Gaps = 71/711 (9%)
Query: 97 RTSQQERGQEGAQDCKFPGNTGRQHRQRHEEE---RQNSHHSQPERQDGDSHHGQPERQD 153
R Q+E +E Q + R+ + R E++ Q Q R++ Q R++
Sbjct: 365 RREQEEERRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Query: 154 RDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHK 213
+ Q E++ H + ER+++ Q ER+D +++ER Q+ + +
Sbjct: 423 QQLRREQEEERHEQKH--EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 214 STSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQ 273
+ +W K ++ Q ER QQ + + +Q+ +
Sbjct: 481 EEERRERWL----------KLEEEERREQQERREQQLRREQEERREQRLKRQE------E 524
Query: 274 SERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQ 333
ERL Q L Q R+ Q Q ++++ Q +R+ Q Q +R+ Q +
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ-ERREQRLKREQEERRDQLLKREE 583
Query: 334 PDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSS---H 390
RQ Q ++ Q +Q ++ + Q R+ Q +P+ + +
Sbjct: 584 ERRQ-------QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 391 YGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSH 450
Q +R+ Q Q ER+ Q + + + + + + + + + +++
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 451 YGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSH 510
+ Q + D + QS YS+P KQ G+ RQ+Q + + + Q
Sbjct: 697 IKSRIPKWQWQLESEADAR-QSKVYSRPRKQE-----GQRRRQEQEEKRRRRESELQWQE 750
Query: 511 YGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYH 570
+ RQ Q + Q ++ + + S G+ + Q +RQ ++
Sbjct: 751 EERAHRQQQE--------EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA-- 800
Query: 571 YGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQ 630
+RQ + ++ + + Q + + + + + EQ R R Q ++G Q
Sbjct: 801 ---EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
Query: 631 NQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLA------QIQQERPLC-HKGRDWQSCS 683
+ +S++ +++ W+ EE+ + +H L A Q+++E+ L + + Q
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917
Query: 684 SEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQ----- 738
E+ RQ Q RQ E EE+ + ++ + +E + K+EQ
Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977
Query: 739 ----NHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRR--DRQTHEDEQNHQ 783
Q R+++ E E+ Q ++ E+++ R+R+ +RQ + ++ Q
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
Score = 79.3 bits (194), Expect = 1e-14
Identities = 127/695 (18%), Positives = 253/695 (36%), Gaps = 51/695 (7%)
Query: 119 RQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDR 178
R+ R+R E+ERQ Q ++++ + E++ R Q K D Q E Q
Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK---DKKLQQKEEQLL 974
Query: 179 DSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDS 238
+ RQ+++ + + E Q+ + + Q +W+ + ++ ++
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ-EWERQYRKKDELQQ--EEE 1031
Query: 239 HYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSE--RLGQELGCGQTDRQGQSSHYG 296
+ ER ++ + + + QQ+ G+ R QEL +RQ +
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL-----ERQYRKEEEL 1086
Query: 297 QTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRK-GQCYHY 355
Q + + + R+ + + + + Q + + +++R+ +
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
Query: 356 DQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHY 415
Q Q + RQ Y + + Q Q R++Q + ERQ +
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEE--QLLREEQEKRRQERERQYREEE- 1203
Query: 416 SQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHY 475
++ RQ + Y D++ +P+++ + ++ + Q +
Sbjct: 1204 -ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
Query: 476 SQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHY 535
SQ D Q + DR+ + + Q D + + Q ++ + DR+ Q
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA---KRRDRKSQEEKQ 1319
Query: 536 SQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEI---- 591
+ + + +TDR+ + +R+ Q + DR+ + + G
Sbjct: 1320 LLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEE 1379
Query: 592 ------QGQNKYFQGTEGTRKASYVEQSGRSGR------LSQQTPGQEGYQNQGQGFQSR 639
Q + + F E + EQ R R QQ QE + + Q
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439
Query: 640 DSQQNGHQVWEPEEDSQHHQHKL------LAQIQQERPLCHKGRDWQSCSSEQGHRQAQT 693
Q+ + E E+ + +H+ L Q ++E+ L + RD + EQ R+ +
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER 1499
Query: 694 RQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQD----RRTHKDEQNHQRRDRQTHE 749
+ E E E+ ++ H Q Q+ RR + +Q Q RDR+ E
Sbjct: 1500 DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE 1559
Query: 750 HEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
EQ Q R+ Q + +RQ RDR+ +EQ +R
Sbjct: 1560 EEQLRQEREEQ----QLSRQERDRKFRLEEQKVRR 1590
Score = 73.9 bits (180), Expect = 5e-13
Identities = 127/717 (17%), Positives = 276/717 (38%), Gaps = 58/717 (8%)
Query: 100 QQERGQEGAQDCKFPGNT----GRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRD 155
+QER ++ +D K G + +R +ER+ + + E Q + + ER+ R
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 156 SHHGQSEKQDRDSHHSQPERQDRDSHHNQS-ERQDKDFSFDQSERQSQDSSSGKKVSHKS 214
+ + + +D + E+ R+ + + +++ + ++ +Q ++ G++ +
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Query: 215 TSGQAKWQGHIFALNRCEKPI------------QDSHYGQSERHTQQSETLGQASHFNQT 262
+ L + E+ + ++ + E Q+ E L + +
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 263 NQQKSGSYCGQSERLGQE---LGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHY 319
Q+ Y + E +E L R+ Q + ++ Q R+ Q
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR 1192
Query: 320 SQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQC---YHYDQTNRQGQGSHYSQPNRQGQS 376
+ +RQ + Q RQ + Y D++ + ++ N Y + Q
Sbjct: 1193 QERERQYREEEELQ--RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 377 SHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQS 436
+D+ S Q D Q + +R+ + + Q DR + + Q ++
Sbjct: 1251 RQLEDSQLRDRQS---QQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307
Query: 437 SHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKID---RQ 493
+ DR+ Q + + + +TDR+ + +++ Q + D R+
Sbjct: 1308 K---RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Query: 494 DQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQ 553
++ H Q G+ + RQ + + + ++Q + Q RQ + + + ++Q
Sbjct: 1365 EELRH--QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 554 GQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQS 613
+ R+ + Q RQ + +++ + Q +++ F+ E + +Q
Sbjct: 1423 LSRQERDRKFREEEQ----QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478
Query: 614 GRSGRLSQQTPGQEGYQNQGQGFQSRDSQ---QNGHQVWEPEEDSQHHQHKLLAQIQQER 670
R R + ++ + Q + + R+ + Q + + EE H Q + +Q+E+
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538
Query: 671 PLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQ--GHQTWDRHSH-ESQEGPCG 727
L + R Q RQ + R+ E EEQ Q DR E Q+
Sbjct: 1539 QLRRQERG-------QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591
Query: 728 TQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQ-NRQRRDRQTHEDEQNHQ 783
Q+R+ +DEQ +R++ Q +Q Q RDR+ ED+Q ++R ++Q H E++ +
Sbjct: 1592 EQERKFMEDEQQLRRQEGQ----QQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Score = 58.2 bits (139), Expect = 3e-08
Identities = 102/533 (19%), Positives = 197/533 (36%), Gaps = 88/533 (16%)
Query: 65 RDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQR 124
++ H F E L+ + + H+ + QQ R QE + + ++ ++
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Query: 125 HEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQ 184
EE Q H Q +R+ Q E+Q R GQ +QDRD + E+ ++ Q
Sbjct: 1517 FLEEEQQLHRQQRQRK-----FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Query: 185 SERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSE 244
RQ++D F E+ + + Q+ + + E
Sbjct: 1572 LSRQERDRKFRLEEQ------------------------------KVRRQEQERKFMEDE 1601
Query: 245 RHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQS 304
+ ++ E GQ Q Q++ + + E+L QE R++Q
Sbjct: 1602 QQLRRQE--GQ----QQLRQERDRKF-REDEQLLQE-------------------REEQQ 1635
Query: 305 YHYGQTDRQ--GQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQG 362
H + DR+ + + +R+ Q H DR + Q+ ++G+ Q RQ
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRH----DRDRKFREEEQLLQEGE---EQQLRRQE 1688
Query: 363 QGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQG 422
+ + + +Q + + Q++ Q RQ+ + + E+ Q + Q+ RQ
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQ----QLRRQELERKFREEEQLRQETEQEQLRRQ- 1743
Query: 423 QGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQG 482
+ R+ +P+R+ Q + DR+ + + +R+ Q + D++
Sbjct: 1744 ------ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
Query: 483 QSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQG 542
+ + +R++Q Q DG+ Y + Q Q Q RQ + Y + + Q
Sbjct: 1798 REEEQLRQEREEQQLRPQQRDGK-----YRWEEEQLQLEEQEQRLRQERDRQY-RAEEQF 1851
Query: 543 QSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTD-RQGQSSHYIQSQTGEIQGQ 594
+ + + Q Q RQ + + R+ Q Q GEI+ Q
Sbjct: 1852 ATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Score = 49.3 bits (116), Expect = 1e-05
Identities = 78/438 (17%), Positives = 167/438 (38%), Gaps = 39/438 (8%)
Query: 369 QPNRQGQSSHYGQPDTQDQSSHYGQT---DRQDQSSHYGQTERQGQSSH-YSQMDRQGQG 424
Q RQ + +P + GQ RQ+Q + E Q + Q DRQ +
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170
Query: 425 SHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQS 484
+ ++ Q + + + S G + + + + +KQ Q
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ- 229
Query: 485 SHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
+ +RQD+ + + + + ++ + +P RQ + + R+ +
Sbjct: 230 ----RRERQDRVFQ--EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 545 SHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGT--- 601
+ +RQ + + R+ Q + +R+ Q + Q Q + + Q
Sbjct: 284 QEL-RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 602 EGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHK 661
+ R+ + + R QQ ++ + + Q + + Q+ ++ + Q +
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 662 LLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAE--------EEQGHQT 713
Q+++E+ L R Q EQ R+ Q + H + H E E++ +
Sbjct: 403 REQQLRREQQL----RREQQLRREQQLRREQEEERHEQ--KHEQERREQRLKREQEERRD 456
Query: 714 WDRHSHESQEGPCGTQDRRTH--KDEQNHQRRDR----QTHEHEQSHQRRDRQ-THEDKQ 766
W + E++ Q+RR K +Q +RR+R + E + +RR++Q E ++
Sbjct: 457 WLKREEETERHE---QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Query: 767 NRQRRDRQTHEDEQNHQR 784
R++R ++ E+E+ QR
Sbjct: 514 RREQRLKRQEEEERLQQR 531
>gi|7706635 cornulin [Homo sapiens]
Length = 495
Score = 128 bits (322), Expect = 2e-29
Identities = 133/531 (25%), Positives = 212/531 (39%), Gaps = 67/531 (12%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
M QLL +I +I+ F +YA+ G+C L + ELK+LL EF D++ +P+DP TV+ +L L
Sbjct: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ 120
LD+D G ++F E+L+LVF++ QAC+ L + G SQ+ +G
Sbjct: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQE---------------SGSL 105
Query: 121 HRQRHEE--ERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQS----EKQDRDSHHSQPE 174
H +E E Q S G + G RQ + GQ+ + Q + + +
Sbjct: 106 HSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVS 165
Query: 175 RQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKP 234
DR + ER Q+Q + GK+ +++T + + Q +R
Sbjct: 166 SYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKR--NQTTEMRPERQPQTREQDRAH-- 221
Query: 235 IQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSH 294
Q+ S T QA QT +Q S G++ + QE Q +G +H
Sbjct: 222 -------QTGETVTGSGTQTQAG-ATQTVEQDSSHQTGRTSKQTQEATNDQ--NRGTETH 271
Query: 295 YGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYH 354
+ Q+ G Q Q+ ++QT +Q Q S G + Q
Sbjct: 272 GQGRSQTSQAVTGGHA--QIQAGTHTQTP--------TQTVEQDSSHQTGSTSTQTQ--- 318
Query: 355 YDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSS--HYGQTERQGQS 412
+ TN Q +G+ R S TQ Q+ + +T QD+S +G QGQ+
Sbjct: 319 -ESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQT 377
Query: 413 SHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHY-------GQ 465
+ G G + Q P Q Q ++ RQ SS + GQ
Sbjct: 378 -----QTQPGSGQRWMQVSNPEAGETV--PGGQAQTGASTESGRQEWSSTHPRRCVTEGQ 430
Query: 466 TDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDR 516
DRQ D + + ++D+ + H QGQ + + R
Sbjct: 431 GDRQPTVVGEEWVDDHSRETVILRLDQ--GNLHTSVSSAQGQDAAQSEEKR 479
Score = 48.9 bits (115), Expect = 2e-05
Identities = 62/259 (23%), Positives = 103/259 (39%), Gaps = 22/259 (8%)
Query: 458 GQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQ 517
G S G+ R G ++ + G+ HY + S+ Q +GQ+ QT Q
Sbjct: 108 GASQELGEGQRSG-----TEVGRAGKGQHY-----EGSSHRQSQQGSRGQNRPGVQTQGQ 157
Query: 518 GQ-SFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDR 576
S DRQ +S ++ Q Q S GQT+ Q Q + G+ ++ + + +R
Sbjct: 158 ATGSAWVSSYDRQAESQSQERISPQIQLS--GQTE-QTQKAGEGKRNQTTEM----RPER 210
Query: 577 QGQSSHYIQS-QTGE-IQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQ 634
Q Q+ ++ QTGE + G Q G + + S ++GR S+QT QN+G
Sbjct: 211 QPQTREQDRAHQTGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGT 268
Query: 635 GFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTR 694
+ Q V Q H E+ H+ + + E + Q +
Sbjct: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGT 328
Query: 695 QSHGEGLSHWAEEEQGHQT 713
+ HG+G S ++ G T
Sbjct: 329 EIHGQGRSQTSQAVTGGHT 347
Score = 38.5 bits (88), Expect = 0.024
Identities = 56/200 (28%), Positives = 80/200 (40%), Gaps = 30/200 (15%)
Query: 579 QSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQS 638
Q S + S + G+ + GTE R G S R SQQ G G G Q
Sbjct: 100 QESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQ--GSRGQNRPGVQTQG 156
Query: 639 RDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHG 698
+ + ++ + +SQ Q ++ QIQ G+ Q+ + +G R QT +
Sbjct: 157 QATGSAWVSSYDRQAESQS-QERISPQIQLS------GQTEQTQKAGEGKRN-QTTEMRP 208
Query: 699 EGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQ--R 756
E E+++ HQT E+ G GTQ Q QT E + SHQ R
Sbjct: 209 ERQPQTREQDRAHQT-----GETVTG-SGTQT----------QAGATQTVEQDSSHQTGR 252
Query: 757 RDRQTHEDKQNRQRRDRQTH 776
+QT E N Q R +TH
Sbjct: 253 TSKQTQE-ATNDQNRGTETH 271
>gi|56606114 trichohyalin-like 1 [Homo sapiens]
Length = 904
Score = 85.5 bits (210), Expect = 2e-16
Identities = 137/700 (19%), Positives = 259/700 (37%), Gaps = 62/700 (8%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
M QLL ++L VI+ FHKYA + + A L ELKQL+ EFGD Q P VE NL
Sbjct: 1 MPQLLRNVLCVIETFHKYASEDSNGATLTGRELKQLIQGEFGDFFQ-PCVLHAVEKNSNL 59
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTG-- 118
L+ D +G I F E++L +F L+ CY + + + +E D TG
Sbjct: 60 LNIDSNGIISFDEFVLAIFNLLNLCYLDIKSLLSSELRQVTKPEKEKLDDVDVQATTGDG 119
Query: 119 --------RQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHH---GQSEKQDRD 167
Q ++ +S PE ++ ++ +H+ SE D
Sbjct: 120 QWTVGTSPTQEKRMLPSGMASSSQLIPEESGAVGNNRVDPWREAKTHNFPGEASEHNDPK 179
Query: 168 SHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFA 227
+ H + + Q ++ + +D + ++ + + K + +G A
Sbjct: 180 NKHLEGDEQSQEVAQDIQTTEDNEGQLKTNKPMAGSKKTSSPTERKGQDKEISQEGDEPA 239
Query: 228 LNRCEKPIQDSHYGQSERH--TQQS---ETLGQASHFNQTNQQKSGSYCGQSERLGQELG 282
+ I+D +G+ E + TQ S E + + +K Q L +E
Sbjct: 240 REQSVSKIRD-QFGEQEGNLATQSSPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQRE-- 296
Query: 283 CGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQ---TDRQGQSSHY--SQPDRQ 337
SS + Q + QT + S + T G+ + ++
Sbjct: 297 ------DEPSSQHADLPEQAAARSPSQTQKSTDSKDVCRMFDTQEPGKDADQTPAKTKNL 350
Query: 338 GQSSHYGQMD--RKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTD 395
G+ YG+ ++ +C D + G + + + + P+ + GQ +
Sbjct: 351 GEPEDYGRTSETQEKECETKDLPVQYGSRNGSETSDMRDERKERRGPEAHGTA---GQKE 407
Query: 396 RQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTD 455
R D+ + E Q Q Y ++ QG + +G + Y +G + + + +
Sbjct: 408 R-DRKTRPLVLETQTQDGKYQEL----QGLSKSKDAEKGSETQY--LSSEGGDQTHPELE 460
Query: 456 RQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTD 515
S + ++G + + + + Q + G+++ +T
Sbjct: 461 GTAVSGEEAEHTKEGTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKTH 520
Query: 516 RQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTD 575
Q G +S + ++ + ++ SS G+ QG S G D
Sbjct: 521 DQPVEEEDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQG--D 578
Query: 576 RQGQSSHYIQSQTGEIQGQNKYFQGTEGTR----KASYVEQSGRSGRLS--QQTPGQEGY 629
+ G+S Q G + QGT G + +A G +L+ Q+ P + +
Sbjct: 579 QHGES-----VQGGHNNNPDTQRQGTPGEKNRALEAVVPAVRGEDVQLTEDQEQPARGEH 633
Query: 630 QNQGQGFQSRDS--QQNGHQVWEPEEDSQHHQHKLLAQIQ 667
+NQG G + + + NGH E +E + +++ +I+
Sbjct: 634 KNQGPGTKGPGAAVEPNGHP--EAQESTAGDENRKSLEIE 671
Score = 37.0 bits (84), Expect = 0.071
Identities = 44/199 (22%), Positives = 79/199 (39%), Gaps = 24/199 (12%)
Query: 580 SSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSR 639
SS I ++G + G N+ E E S + ++ G E Q Q Q+
Sbjct: 141 SSQLIPEESGAV-GNNRVDPWREAKTHNFPGEASEHNDPKNKHLEGDEQSQEVAQDIQTT 199
Query: 640 DSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGE 699
+ + + +P S+ + P KG+D + S++G A+ QS +
Sbjct: 200 EDNEGQLKTNKPMAGSK----------KTSSPTERKGQDKEI--SQEGDEPAR-EQSVSK 246
Query: 700 GLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNH------QRRDRQTHEH--- 750
+ E+E T E+ + PC Q+ RT K++ ++ QR D + +H
Sbjct: 247 IRDQFGEQEGNLATQSSPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQREDEPSSQHADL 306
Query: 751 -EQSHQRRDRQTHEDKQNR 768
EQ+ R QT + ++
Sbjct: 307 PEQAAARSPSQTQKSTDSK 325
Score = 36.6 bits (83), Expect = 0.092
Identities = 77/389 (19%), Positives = 137/389 (35%), Gaps = 41/389 (10%)
Query: 385 QDQSSHYGQTDRQDQSSHYGQTERQGQSSHYS-----QMDRQGQGSHYGQTDRQGQSSHY 439
+D S + Q+D + +G SS + Q D Q QG +G++ + G H
Sbjct: 533 EDPESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQGDQHGESVQGG---HN 589
Query: 440 GQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHY 499
PD Q Q + G+ +R ++ Q + + +G+ + G + +
Sbjct: 590 NNPDTQRQGTP-GEKNRALEAVVPAVRGEDVQLTEDQEQPARGEHKNQGPGTKGPGAAVE 648
Query: 500 GQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHY 559
+ Q S G +R+ + + S M G+ + QG SS
Sbjct: 649 PNGHPEAQESTAGDENRKSLEIEITGALDEDFTDQLSLMQLPGKGDSRNELKVQGPSSKE 708
Query: 560 GQ-TDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGR 618
+ + Q+ D +S IQ +T E T S E +G G
Sbjct: 709 EKGRATEAQNTLLESLDEDNSASLKIQLETKE--------PVTSEEEDESPQELAGEGG- 759
Query: 619 LSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRD 678
Q++P ++ + + Q + E + + L Q QE+ L
Sbjct: 760 -DQKSPAKKEHNSSVPWSSLEKQMQRDQEPCSVERGAVYSSP--LYQYLQEKIL-----Q 811
Query: 679 WQSCSSEQGHRQAQTRQSHGEGLSHWA--EEEQGHQTWDRHSHESQ---------EGPCG 727
+ + E+ +Q Q Q+ G L + E + +S SQ E P G
Sbjct: 812 QTNVTQEEHQKQVQIAQASGPELCSVSLTSEISDCSVFFNYSQASQPYTRGLPLDESPAG 871
Query: 728 TQDR---RTHKDEQNHQRRDRQTHEHEQS 753
Q+ + +D+Q H +R+R + E S
Sbjct: 872 AQETPAPQALEDKQGHPQRERLVLQREAS 900
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 83.6 bits (205), Expect = 7e-16
Identities = 116/480 (24%), Positives = 184/480 (38%), Gaps = 100/480 (20%)
Query: 88 KLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNS----HHSQPERQDGD 143
KL +K H + +ER G + + R HR E +++S HHS +R
Sbjct: 1533 KLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRS--- 1589
Query: 144 SHHGQPERQDRDSHHGQSEKQDRDSHH-SQPERQ----DRDSHHNQSERQDKDFSFDQSE 198
H P R++ S +S + +H S PER H+ S+R + S +
Sbjct: 1590 --HCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHH 1647
Query: 199 RQSQDS-SSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQAS 257
S+ S S + SH+S+S + R P Q SH G SER
Sbjct: 1648 SPSERSHRSPSERSHRSSSER-----------RHRSPSQRSHRGPSER------------ 1684
Query: 258 HFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSS 317
S+C SER + Q SH G ++R+ S + S
Sbjct: 1685 -----------SHCSPSERRHRS--------PSQRSHRGPSERRHHSPSKRSHRSPARRS 1725
Query: 318 HYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQ----GQGSHYSQPNRQ 373
H S ++R SH+S +R SH+ +R+ H+ + R + SH S R+
Sbjct: 1726 HRSPSER----SHHSPSER----SHHSPSERR----HHSPSERSHCSPSERSHCSPSERR 1773
Query: 374 GQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQS----SHYSQMDRQGQGSHYGQ 429
+S + + + SH+ ++R SH+ +ER+ S S +S ++R SH
Sbjct: 1774 HRSPSERRHHSPSEKSHHSPSER----SHHSPSERRRHSPLERSRHSLLER----SHRSP 1825
Query: 430 TDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGK 489
++R+ S R + SH + SH +R S S +++G SS GK
Sbjct: 1826 SERRSHRSFERSHRRISERSH-----SPSEKSHLSPLER----SRCSPSERRGHSSS-GK 1875
Query: 490 IDRQDQSYHYGQPDGQGQS-----SHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
+ P G Q SH +R S +P R +H S +R +S
Sbjct: 1876 TCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRS 1935
Score = 69.3 bits (168), Expect = 1e-11
Identities = 87/414 (21%), Positives = 154/414 (37%), Gaps = 33/414 (7%)
Query: 317 SHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQS 376
+H S ++R +SS + Q SH + Q +H S P R S
Sbjct: 1565 NHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHS 1624
Query: 377 SHYGQPDTQDQSSHYGQTDRQDQS----SHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432
+ Q SH G + R+ S SH +ER +SS + Q SH G ++R
Sbjct: 1625 LSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSER 1684
Query: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQS----SHYGQTDRQGQSSHYSQPDKQGQSSHYG 488
S + Q SH G ++R+ S SH R +S + SH+
Sbjct: 1685 SHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHS 1744
Query: 489 KIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYG 548
+R+ S + SH ++R+ +S + + SH+S +R SH+
Sbjct: 1745 PSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSER----SHHS 1800
Query: 549 QTDRQGQS----SHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGT 604
++R+ S S + +R +S ++ R + SH S+ + + E +
Sbjct: 1801 PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERS 1860
Query: 605 RKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLA 664
R + + S + +P + +++ Q R S+++ E S
Sbjct: 1861 RCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSP-------- 1912
Query: 665 QIQQERPLCHKGRDWQSCSSEQGHRQAQTRQS-----HGEGLSHWAEEEQGHQT 713
+ RP GR+ CS + R++ ++ GE SH + +QT
Sbjct: 1913 --SEMRPGRPSGRN--HCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQT 1962
Score = 65.9 bits (159), Expect = 1e-10
Identities = 100/471 (21%), Positives = 169/471 (35%), Gaps = 79/471 (16%)
Query: 215 TSGQAKWQGHIFALNRCEKP-IQDSHYGQSER-HTQQSETLGQASHFNQTNQQKSGSYCG 272
T W+ H R ++ ++ H+ S+R H S + ++C
Sbjct: 1557 TRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCS 1616
Query: 273 QSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYS 332
ER L Q SH G + R+ H+ ++R SH S ++R +SS
Sbjct: 1617 PPERSCHSLSERGLHSPSQRSHRGPSQRR----HHSPSER----SHRSPSERSHRSSSER 1668
Query: 333 QPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYG 392
+ Q SH G +R SH S R+ +S Q SH G
Sbjct: 1669 RHRSPSQRSHRGPSER----------------SHCSPSERRHRS--------PSQRSHRG 1704
Query: 393 QTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYG 452
++R+ S + SH S +R SH+ ++R S + + SH
Sbjct: 1705 PSERRHHSPSKRSHRSPARRSHRSPSER----SHHSPSERSHHSPSERRHHSPSERSHCS 1760
Query: 453 QTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYG 512
++R SH ++R+ +S + + SH+ +R S + + S +
Sbjct: 1761 PSER----SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHS 1816
Query: 513 QTDRQGQSFHYGQPDRQGQSSHYSQMDRQ---GQSSHYGQTDRQGQSSHYGQTDRQGQSY 569
+R +S + R + SH +R + SH +R S ++R+G S
Sbjct: 1817 LLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLER----SRCSPSERRGHSS 1872
Query: 570 HYGQTDRQGQSSHYIQSQTGEIQG---QNKYFQGTEGTRKASYVEQSGR-SGR------- 618
+ SH +S +G QG + + E TR + + GR SGR
Sbjct: 1873 SGKTCHSPSERSH--RSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSE 1930
Query: 619 LSQQTPGQEG-----------------YQNQGQGFQSRDSQQNGHQVWEPE 652
S+++P +EG ++NQ + QVW PE
Sbjct: 1931 RSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPE 1981
Score = 60.8 bits (146), Expect = 5e-09
Identities = 81/405 (20%), Positives = 143/405 (35%), Gaps = 51/405 (12%)
Query: 365 SHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQG 424
+H S R +SS + + Q SH + + S Q +H S +R
Sbjct: 1565 NHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHS 1624
Query: 425 SHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQS 484
Q SH G R+ H+ ++R SH ++R +SS + Q
Sbjct: 1625 LSERGLHSPSQRSHRGPSQRR----HHSPSER----SHRSPSERSHRSSSERRHRSPSQR 1676
Query: 485 SHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
SH G +R S + Q SH G ++R+ S + SH S +R
Sbjct: 1677 SHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER---- 1732
Query: 545 SHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGT 604
SH+ ++R SH+ ++R+ H+ ++R SH S+ + +
Sbjct: 1733 SHHSPSER----SHHSPSERR----HHSPSER----SHCSPSERSHCSPSERRHRSPSER 1780
Query: 605 RKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLA 664
R S E+S S P + + + + + +++ H + E H+ +
Sbjct: 1781 RHHSPSEKSHHS-------PSERSHHSPSERRRHSPLERSRHSLLE-------RSHRSPS 1826
Query: 665 QIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGH-QTWDRHSHESQE 723
+ + R S E+ HR+ R SH + E+ +R H S
Sbjct: 1827 ERRSHR------------SFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSG 1874
Query: 724 GPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNR 768
C + R+H+ ++ H S +R E + R
Sbjct: 1875 KTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGR 1919
Score = 43.5 bits (101), Expect = 8e-04
Identities = 65/335 (19%), Positives = 119/335 (35%), Gaps = 60/335 (17%)
Query: 464 GQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQ----GQ 519
G ++R + + + S ++R+ S + +H ++R Q
Sbjct: 1552 GPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQ 1611
Query: 520 SFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQ 579
H P+R S + Q SH G + R+ H+ ++R +S +
Sbjct: 1612 RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRR----HHSPSERSHRS--------PSE 1659
Query: 580 SSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRS-GRLSQQTPGQEGYQNQGQGFQS 638
SH S+ + +G S E+ RS + S + P + + + +
Sbjct: 1660 RSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKR-SH 1718
Query: 639 RDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHG 698
R + H+ P E S H SE+ H R+ H
Sbjct: 1719 RSPARRSHR--SPSERSHHSP------------------------SERSHHSPSERRHHS 1752
Query: 699 EG-LSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHK-DEQNHQRRDRQTHEHEQSHQR 756
SH + E+ H + H S +RR H E++H ++H H S +R
Sbjct: 1753 PSERSHCSPSERSHCSPSERRHRSPS------ERRHHSPSEKSHHSPSERSH-HSPSERR 1805
Query: 757 R----DRQTHE--DKQNRQRRDRQTHED-EQNHQR 784
R +R H ++ +R +R++H E++H+R
Sbjct: 1806 RHSPLERSRHSLLERSHRSPSERRSHRSFERSHRR 1840
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 81.3 bits (199), Expect = 3e-15
Identities = 94/541 (17%), Positives = 150/541 (27%), Gaps = 12/541 (2%)
Query: 115 GNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPE 174
GN G + + + S S + D + + D DS S S +
Sbjct: 530 GNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589
Query: 175 RQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKP 234
D DS + + D S S DSS K S KS S + + +
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Query: 235 IQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSH 294
D+ ++ S +S + ++ S S ++ SS
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709
Query: 295 YGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYH 354
+D D S SS S + SS S SS
Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769
Query: 355 YDQTNRQGQGSHYSQPNRQGQSSHYG-QPDTQDQSSHYGQTDRQD-------QSSHYGQT 406
++ S+ S N SS ++ D S+ +D D SS +
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829
Query: 407 ERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQT 466
SS+ S S +D +S D + +D SS ++
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD-SSDSSDSNES 888
Query: 467 DRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQP 526
SS S S D D S + S + +D S
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948
Query: 527 D--RQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYI 584
D SS+ S SS +D S+ +D S +D S
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 585 QSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRL-SQQTPGQEGYQNQGQGFQSRDSQQ 643
S + + + ++ + + + S S S + N S DS
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068
Query: 644 N 644
+
Sbjct: 1069 S 1069
Score = 80.9 bits (198), Expect = 4e-15
Identities = 88/527 (16%), Positives = 159/527 (30%), Gaps = 13/527 (2%)
Query: 91 NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPE 150
N +S + + + K GN G + +++ ++ + +G+ ++G +
Sbjct: 478 NSESDNNSSSRGDASYNSDESKDNGN-GSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD 536
Query: 151 RQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
DS G+S+ D DS S DS + S + D S+ S DSS
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596
Query: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSY 270
++S + + + + S +SE + S++ +S N ++ +
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656
Query: 271 CGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSH 330
S +D SS ++ D S D S+ +D S
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS------DSSDSSNSSESSDSSDSSDS 710
Query: 331 YSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSH 390
S +S+ D D +N N S ++ D S
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 391 YGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSH 450
+D D S+ + SS+ S S + SS D +
Sbjct: 771 SDSSDSSDSSN----SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826
Query: 451 YGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSH 510
+D SS+ + SS S D +S D D S D S
Sbjct: 827 SNSSD-SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 511 YGQTDRQGQSFHYGQPDR-QGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSY 569
++ S D SS+ S SS ++ +S+ + S
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945
Query: 570 HYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRS 616
+ SS+ S + ++ + + + S S
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Score = 74.7 bits (182), Expect = 3e-13
Identities = 89/529 (16%), Positives = 142/529 (26%), Gaps = 13/529 (2%)
Query: 128 ERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSER 187
+ +S +S DS DS+ + DS +S DS + S+
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS-DSSDS 815
Query: 188 QDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT 247
D D S S DSS S S S + + NR DS +
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR-----SDSSNSSDSSDS 870
Query: 248 QQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHY 307
S +S + +N+ + S S + + SS + +S +
Sbjct: 871 SDSSNSSDSSDSSDSNESSNSSDSSDSSN-SSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 308 GQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHY 367
SS+ S + SS+ S SS+ D +N
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 368 SQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHY 427
+ S D+ D S ++ D S+ + S D
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Query: 428 GQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHY 487
+D S D + +D S +D S D S
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 488 GKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHY 547
D D S D S +D S + S D S
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 548 GQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKA 607
+D S+ +D S +D S S + + + ++ + +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 608 SYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQ 656
E S S S + + S DS + + E DSQ
Sbjct: 1230 DSNESSDSSD--SSDSSDSSNSSDSSDSSDSSDSTSDSND----ESDSQ 1272
Score = 55.1 bits (131), Expect = 3e-07
Identities = 114/716 (15%), Positives = 205/716 (28%), Gaps = 56/716 (7%)
Query: 95 GGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDG-----DSHHGQP 149
G S + C+ GNT Q + + R + ++ G D+ G P
Sbjct: 188 GSNNSTDNEDEIIENSCRNEGNTSEITPQINSK-RNGTKEAEVTPGTGEDAGLDNSDGSP 246
Query: 150 ERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSS---- 205
D + D D + +S + + K+ D S Q+ DS
Sbjct: 247 SGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYD 306
Query: 206 -SGKKVSHKSTSGQAKWQGHIFALNRCE-------KPIQDSHYGQSE----RHTQQSETL 253
GK+ H G + + E + Q ++ +S+ R T++SET
Sbjct: 307 PEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESET- 365
Query: 254 GQASHFNQTNQQKSGSYCGQS---ERLGQELGCGQTDRQGQSSH-----YGQTDRQDQSY 305
H +Q K G S + +E+G G ++ + H G Q +
Sbjct: 366 ----HAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVV 421
Query: 306 HY---GQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQG 362
+ GQ G +S T S Y D +S + + D N +
Sbjct: 422 NIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSES 481
Query: 363 Q-----------GSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQ 411
S S+ N G S + D D +S +D ++ G +
Sbjct: 482 DNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNN-GNDDNDKS 540
Query: 412 SSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQ 471
S + D S + SS D NS SS +D
Sbjct: 541 DSGKGKSDSSDSDS--SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS 598
Query: 472 SSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQ 531
S+ D S D D + + S S
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Query: 532 SSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEI 591
SS+ S SS + SS+ + S + ++ SS S + +
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 718
Query: 592 QGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEP 651
N + + +S S S S + + + S S + +
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS--DS 776
Query: 652 EEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGH 711
+ S + + S S + + S+ S+ ++
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 712 QTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQN 767
+ D S +S + G+ +++ + ++ + + S D + N
Sbjct: 837 NSSD--SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Score = 33.5 bits (75), Expect = 0.78
Identities = 71/470 (15%), Positives = 154/470 (32%), Gaps = 46/470 (9%)
Query: 347 DRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQT 406
DR Q D +G GS +++ + S++ ++ + G ++ YG
Sbjct: 65 DRGRQENTQDGHKGEGNGSKWAEVGGKSFSTY--STLANEEGNIEGWNGDTGKAETYGHD 122
Query: 407 ERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQT 466
G+ + + QGQ S +S+ G D+ QN G + +
Sbjct: 123 GIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQED 182
Query: 467 DRQGQSSHYSQPDKQ-------GQSSHYGKIDRQDQSYHYGQPDGQ---GQSSHYGQTDR 516
Q S+ S ++ + +I Q S G + + G G +
Sbjct: 183 GPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNS 242
Query: 517 QGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDR 576
G G + + + S + + G + + +G+ D S +
Sbjct: 243 DGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSK 302
Query: 577 QGQSSHYIQSQTGEIQG--------------QNKYFQGTEGTRKASYVEQSGRSGRLSQQ 622
+ + E+ G ++ Q E T+K ++ E R++++
Sbjct: 303 EYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKE 362
Query: 623 TPGQEGYQNQGQGFQSRDSQQNGHQVWE--------PEEDSQHHQHKLLAQIQQERPLCH 674
+ ++Q +G + + + + E+ QH ++ + + +
Sbjct: 363 SETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVN 422
Query: 675 KGRDWQSCSSEQGHRQAQTR---QSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDR 731
Q SE G++ + S+ +G + +++ Q D +S + G D
Sbjct: 423 IEGPGQ--KSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESN---GNDDA 477
Query: 732 RTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQN 781
+ D + R D + S + +D D + + D + D N
Sbjct: 478 NSESDNNSSSRGDASYN----SDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Score = 31.2 bits (69), Expect = 3.9
Identities = 26/130 (20%), Positives = 40/130 (30%), Gaps = 3/130 (2%)
Query: 91 NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPE 150
++S S + D ++ + +S S DS
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207
Query: 151 RQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
DS DS S + DS + S+ D S D S+ S DSS
Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSS-DSSDSSDSSNSSDSSD--SSDSSDSTSD 1264
Query: 211 SHKSTSGQAK 220
S+ + Q+K
Sbjct: 1265 SNDESDSQSK 1274
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 78.2 bits (191), Expect = 3e-14
Identities = 79/438 (18%), Positives = 175/438 (39%), Gaps = 35/438 (7%)
Query: 103 RGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQ------DGDSHHGQPERQDRDS 156
R + G+Q+ G+ H+ ++R+ + + ER+ + ++ + R+++D
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 157 HHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTS 216
H + ++R + + D ++ ++++ Q ER+ + G++ + T
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERN---RQKERERETEREGERGRDRQTD 144
Query: 217 GQAKWQGHIFALNRCEKPIQDSHYGQSERHTQ---QSETLGQASHFNQTNQQKSGSYCGQ 273
GQ + + A E+ Q+ER+ Q + E Q + ++K +
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
Query: 274 SERLGQELGC-----GQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQS 328
G+E +T+R+ Q+ R+ + Q +R+ S ++ D++ +
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER 264
Query: 329 SHYSQPDR-QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQ 387
DR + Q Q DRK Q +T R + + R+ + + +
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQ----RRTERDRETERKRERQRERERERERNRKRERE 320
Query: 388 SSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQ 447
+ +RQ ++ + ER+ + ++MDR+ QT R+G+ + +R+ +
Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRE----RNRQTGREGRRQAERERERERE 376
Query: 448 NSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQ-DQSYHYGQPDGQG 506
+R+ + DRQ + ++ D+ GQ + +R+ D+ G+ G+
Sbjct: 377 RDRQSARERE-ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435
Query: 507 QSSHYG-------QTDRQ 517
+ G QTDRQ
Sbjct: 436 REKQKGRERDRERQTDRQ 453
Score = 73.9 bits (180), Expect = 5e-13
Identities = 77/437 (17%), Positives = 178/437 (40%), Gaps = 25/437 (5%)
Query: 359 NRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQT------DRQDQSSHYGQTERQGQS 412
+R+ GS S P R+G + D D+ + + RQ + + ER+ +
Sbjct: 27 SRRRPGSQES-PRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 413 SHYSQMDRQGQGSHYGQTDRQGQSSH----YGQPDRQGQNSHYGQTDRQGQSSHYGQTDR 468
+ + DR + + +R+ Q+ + +R Q +T+R+G+ QTD
Sbjct: 86 DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD- 144
Query: 469 QGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQP-D 527
GQ Q D + + +RQ Q+ Q + + + + + +R+ Q + D
Sbjct: 145 -GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Query: 528 RQGQSSHYSQMDRQGQSS--HYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQ 585
R + + +R+ ++ QTDR+ + +R+ Q+ ++R+ + +
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 586 SQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNG 645
+ + +++ + E ++ R ++ Q + + + + R+ ++
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER 323
Query: 646 HQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWA 705
+ E + +++ + K + ++ + + R+ Q+ +G RQA+ + +
Sbjct: 324 ERERERQRETERDREKERERKRKRQTEMDRERNRQT--GREGRRQAERERERERERDRQS 381
Query: 706 EEEQGHQTWDRHSHESQEGPCGTQDRRTHKDE--QNHQRRDRQTHEHEQSHQRRDRQTHE 763
E+ + DR +E ++R+T KD Q + R+ + +S + R+R
Sbjct: 382 AREREERERDRDRDRQKE-----RERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436
Query: 764 DKQNRQRRDRQTHEDEQ 780
+KQ + RDR+ D Q
Sbjct: 437 EKQKGRERDRERQTDRQ 453
Score = 67.0 bits (162), Expect = 6e-11
Identities = 70/402 (17%), Positives = 154/402 (38%), Gaps = 44/402 (10%)
Query: 90 DNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQP 149
D + R ++ R +E ++ + G GR + + ER+ ++ ER
Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKER---------- 159
Query: 150 ERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFD-------QSERQSQ 202
ERQ Q+E+ + + RQ+R Q E+++K + ER+++
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Query: 203 DSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQT 262
+ K+ + + Q K + E+ Q SER T++ + + ++
Sbjct: 220 TETERKRQTDRERDRQRKTER--------EREKQAERERASERETERDKERERERDRDRD 271
Query: 263 NQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQT 322
++ Q++R Q +T+R ++ + R+ + R+ + +
Sbjct: 272 RDRRQKERERQTDRKRQR----RTERDRETERKRERQRERERERERNRKRERERERERER 327
Query: 323 DRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQP 382
+RQ ++ + +R+ + +MDR+ + RQ + + R QS+ +
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 383 DTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQP 442
+D+ DRQ + + +R GQ Q +R + DR+ +
Sbjct: 388 RERDR-----DRDRQKERERQTEKDRDGQRETEKQRER--------EKDRESERGRERGR 434
Query: 443 DRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQS 484
+R+ Q + DR+ Q+ R+ + + + P + +S
Sbjct: 435 EREKQKGR--ERDRERQTDRQAGRQRKRSTLYVNPPPRTARS 474
Score = 62.4 bits (150), Expect = 2e-09
Identities = 64/351 (18%), Positives = 145/351 (41%), Gaps = 24/351 (6%)
Query: 444 RQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPD 503
RQ + + +R+ + + + DR + + +++ Q+ + DRQ + Q +
Sbjct: 69 RQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR--ERDRQREKERNRQKE 126
Query: 504 GQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTD 563
+ ++ G+ R Q+ GQ +R+ Q + +RQ QT+R Q + +
Sbjct: 127 RERETEREGERGRDRQTD--GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN 184
Query: 564 RQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQT 623
RQ + Q +++ ++ S+ G + + + + TE RK + R + ++
Sbjct: 185 RQERRERERQREKENKTEDR-HSERGRERERERETE-TETERKRQTDRERDRQRKTERER 242
Query: 624 PGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCS 683
Q + + RD ++ + + + D + + + +++R + R+ +
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT-ERDRETERKR 301
Query: 684 SEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRR 743
Q R+ + ++ E E+ Q E + ++R+ + + + R
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKE------RERKRKRQTEMDRER 355
Query: 744 DRQT-------HEHEQSHQR-RDRQTHEDKQNRQR---RDRQTHEDEQNHQ 783
+RQT E E+ +R RDRQ+ +++ R+R RDRQ + Q +
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
Score = 50.4 bits (119), Expect = 6e-06
Identities = 56/296 (18%), Positives = 116/296 (39%), Gaps = 36/296 (12%)
Query: 518 GQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQ 577
GQ+ D + ++ + R+ + +TDR+ + R+ + Q DR+
Sbjct: 43 GQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE 102
Query: 578 GQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQ 637
+ + QT + + + + + E+ G GR +QT GQ + Q +
Sbjct: 103 KER----ERQTDRERDRQREKERNRQKERERETEREGERGR-DRQTDGQRERERQRDAEK 157
Query: 638 SRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCS----SEQGHRQAQT 693
R+ Q + + + E + Q + + + +QER + R+ ++ + SE+G + +
Sbjct: 158 ERERQTDRERQRQTERNRQKERER--EKNRQERRERERQREKENKTEDRHSERGRERERE 215
Query: 694 RQSHGEG-LSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDR------- 745
R++ E + E+ Q E Q +R T +D++ + RDR
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 746 -----------------QTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
+ E E+ +R+ + E ++NR+R + E E+ QR
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/166 (19%), Positives = 71/166 (42%), Gaps = 5/166 (3%)
Query: 620 SQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLC-HKGRD 678
SQ++P + G + D ++N + E + + + + + ++ R H+ RD
Sbjct: 33 SQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRD 92
Query: 679 WQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQ 738
Q R+ + + E+E+ Q +R +EG G +DR+T +
Sbjct: 93 RHR--ERQRDREKERERQTDRERDRQREKERNRQK-ERERETEREGERG-RDRQTDGQRE 148
Query: 739 NHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
++RD + Q+ + R RQT ++Q + R++ E + ++
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ 194
Score = 37.4 bits (85), Expect = 0.054
Identities = 17/70 (24%), Positives = 30/70 (42%)
Query: 714 WDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDR 773
+ R SQE P + HKD R + E E+ ++R + D++ +RR++
Sbjct: 26 FSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 774 QTHEDEQNHQ 783
H H+
Sbjct: 86 DRHRKRDRHR 95
Score = 36.2 bits (82), Expect = 0.12
Identities = 23/132 (17%), Positives = 61/132 (46%), Gaps = 7/132 (5%)
Query: 88 KLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHG 147
K ++ R ++++R ++ ++ + N R+ + E ER+ ++ +R+
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
Query: 148 QPERQ---DRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQ---DKDFSFDQSERQS 201
+ + + +R+ G+ ++ + + +DR S + ER+ D+D + ERQ+
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQ-KERERQT 404
Query: 202 QDSSSGKKVSHK 213
+ G++ + K
Sbjct: 405 EKDRDGQRETEK 416
>gi|221316609 sperm-associated cation channel 1 [Homo sapiens]
Length = 780
Score = 75.5 bits (184), Expect = 2e-13
Identities = 82/388 (21%), Positives = 146/388 (37%), Gaps = 51/388 (13%)
Query: 366 HYSQPNRQGQSSHYGQ-PDTQDQ--SSHYGQTDRQDQSSHYGQ----------------- 405
H+ P+++G+S H + D DQ SSH Q+ ++ ++G+
Sbjct: 47 HHGVPHQRGESHHPPEFQDFHDQALSSHVHQSHHHSEARNHGRAHGPTGFGLAPSQGAVP 106
Query: 406 TERQGQSSHYSQMDRQGQ----GSHYGQTDRQGQS-----SHYGQPDRQGQN-SHYGQ-T 454
+ R ++ ++ R G+ GS YG +Q S SH+G+P G+N SHY
Sbjct: 107 SHRSYGEDYHDELQRDGRRHHDGSQYGGFHQQSDSHYHRGSHHGRPQYLGENLSHYSSGV 166
Query: 455 DRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYH---------YGQPDGQ 505
G++SH+G + + YS+ ++SH + + +H + Q
Sbjct: 167 PHHGEASHHGGSYLPHGPNPYSESFHHSEASHLSGLQHDESQHHQVPHRGWPHHHQVHHH 226
Query: 506 GQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQ 565
G+S H+ + + G+S H+G+ S Q S Y Q D H+G
Sbjct: 227 GRSRHH-EAHQHGKSPHHGETISPHSSVGSYQRGISDYHSEYHQGDHHPSEYHHGDHPHH 285
Query: 566 GQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPG 625
Q +HY QT R + H Q G + + T + S + + RS L PG
Sbjct: 286 TQ-HHYHQTHRH-RDYHQHQDHHGAYHSSYLHGDYVQSTSQLS-IPHTSRS--LIHDAPG 340
Query: 626 QEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDW-----Q 680
+ + + + H + + ++ ++ + DW Q
Sbjct: 341 PAASRTGVFPYHVAHPRGSAHSMTRSSSTIRSRVTQMSKKVHTQDISTKHSEDWGKEEGQ 400
Query: 681 SCSSEQGHRQAQTRQSHGEGLSHWAEEE 708
+ G Q ++ H L W E+
Sbjct: 401 FQKRKTGRLQRTRKKGHSTNLFQWLWEK 428
Score = 64.7 bits (156), Expect = 3e-10
Identities = 62/259 (23%), Positives = 105/259 (40%), Gaps = 18/259 (6%)
Query: 289 QGQSSHYGQTDRQDQSYHYGQTDRQ-----GQSSHYSQTDRQGQSSHYSQPDRQGQSSHY 343
Q SSH Q+ ++ ++G+ S + R ++ + R G+ H
Sbjct: 69 QALSSHVHQSHHHSEARNHGRAHGPTGFGLAPSQGAVPSHRSYGEDYHDELQRDGRRHHD 128
Query: 344 GQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQS-SHY--GQPDTQDQSSHYGQTDRQDQS 400
G +H + +GSH+ +P G++ SHY G P ++SH+G +
Sbjct: 129 GSQYGG---FHQQSDSHYHRGSHHGRPQYLGENLSHYSSGVPH-HGEASHHGGSYLPHGP 184
Query: 401 SHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQS 460
+ Y ++ ++SH S + Q S + Q +G H+ Q G++ H+ + + G+S
Sbjct: 185 NPYSESFHHSEASHLSGL--QHDESQHHQVPHRGWPHHH-QVHHHGRSRHH-EAHQHGKS 240
Query: 461 SHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQS 520
H+G+T S Q S Y + D YH+G Q HY QT R +
Sbjct: 241 PHHGETISPHSSVGSYQRGISDYHSEYHQGDHHPSEYHHGDHPHHTQ-HHYHQTHRH-RD 298
Query: 521 FHYGQPDRQGQSSHYSQMD 539
+H Q S Y D
Sbjct: 299 YHQHQDHHGAYHSSYLHGD 317
Score = 63.5 bits (153), Expect = 7e-10
Identities = 90/390 (23%), Positives = 139/390 (35%), Gaps = 65/390 (16%)
Query: 132 SHHSQPERQDGDS---------HHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHH 182
SH S P + G S HHG P Q +SHH PE QD H
Sbjct: 25 SHSSPPHHRPGHSRALHHYELHHHGVPH-QRGESHH-------------PPEFQD---FH 67
Query: 183 NQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQ 242
+Q+ S SE ++ + G + G A QG + + + D
Sbjct: 68 DQALSSHVHQSHHHSEARNHGRAHG-----PTGFGLAPSQGAVPSHRSYGEDYHDELQRD 122
Query: 243 SERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQ-TDRQ 301
RH S+ G H + GS+ G+ + LG+ L SHY
Sbjct: 123 GRRHHDGSQYGG--FHQQSDSHYHRGSHHGRPQYLGENL-----------SHYSSGVPHH 169
Query: 302 DQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQ 361
++ H+G + + YS++ ++SH S Q S + Q+ +G +H+ Q +
Sbjct: 170 GEASHHGGSYLPHGPNPYSESFHHSEASHLS--GLQHDESQHHQVPHRGWPHHH-QVHHH 226
Query: 362 GQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQ 421
G+ H+ + ++ G+S H+G+ + S Q D S Y Q + H+
Sbjct: 227 GRSRHH-EAHQHGKSPHHGETISPHSSVGSYQRGISDYHSEYHQGDHHPSEYHHGDHPHH 285
Query: 422 GQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQP--- 478
Q HY QT R D H+G Y Q+ Q H S+
Sbjct: 286 TQ-HHYHQTHR--------HRDYHQHQDHHGAYHSSYLHGDYVQSTSQLSIPHTSRSLIH 336
Query: 479 DKQGQSSHYGKIDRQDQSYHYGQPDGQGQS 508
D G ++ + YH P G S
Sbjct: 337 DAPGPAASRTGV----FPYHVAHPRGSAHS 362
Score = 54.3 bits (129), Expect = 4e-07
Identities = 64/311 (20%), Positives = 112/311 (36%), Gaps = 23/311 (7%)
Query: 193 SFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT----Q 248
S + + D+++ + +S GH AL+ E + + E H Q
Sbjct: 5 SVPEKAQNEADTNNADRFFRSHSSPPHHRPGHSRALHHYELHHHGVPHQRGESHHPPEFQ 64
Query: 249 QSETLGQASHFNQTNQQKSGSYCGQSER-----LGQELGCGQTDRQGQSSHYGQTDRQDQ 303
+SH +Q++ G++ L G + R ++ + R +
Sbjct: 65 DFHDQALSSHVHQSHHHSEARNHGRAHGPTGFGLAPSQGAVPSHRSYGEDYHDELQRDGR 124
Query: 304 SYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQS-SHYGQ-MDRKGQCYHYDQTNRQ 361
+H G Q H + SH+ +P G++ SHY + G+ H+ +
Sbjct: 125 RHHDGS---QYGGFHQQSDSHYHRGSHHGRPQYLGENLSHYSSGVPHHGEASHHGGSYLP 181
Query: 362 GQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQ 421
+ YS+ ++SH D+S H+ R H+ Q G+S H+ + +
Sbjct: 182 HGPNPYSESFHHSEASHLSGLQ-HDESQHHQVPHRG--WPHHHQVHHHGRSRHH-EAHQH 237
Query: 422 GQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQP--- 478
G+ H+G+T S Q +S Y Q D H+G Q HY Q
Sbjct: 238 GKSPHHGETISPHSSVGSYQRGISDYHSEYHQGDHHPSEYHHGDHPHHTQ-HHYHQTHRH 296
Query: 479 -DKQGQSSHYG 488
D H+G
Sbjct: 297 RDYHQHQDHHG 307
Score = 53.1 bits (126), Expect = 1e-06
Identities = 75/340 (22%), Positives = 126/340 (37%), Gaps = 60/340 (17%)
Query: 447 QNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQG 506
QNS + + +++ + R S + +P HY + +H+G P +G
Sbjct: 3 QNSVPEKAQNEADTNNADRFFRSHSSPPHHRPGHSRALHHY-------ELHHHGVPHQRG 55
Query: 507 QSSHYGQTDRQGQSFH-YGQPDRQGQSSHYSQMDRQGQS---SHYGQTDRQGQ------- 555
+S H + Q FH QS H+S+ G++ + +G QG
Sbjct: 56 ESHH----PPEFQDFHDQALSSHVHQSHHHSEARNHGRAHGPTGFGLAPSQGAVPSHRSY 111
Query: 556 -SSHYGQTDRQGQSYH----YGQTDRQGQSSHYIQSQTGEIQ--GQN--KYFQGTEGTRK 606
++ + R G+ +H YG +Q S ++ S G Q G+N Y G +
Sbjct: 112 GEDYHDELQRDGRRHHDGSQYGGFHQQSDSHYHRGSHHGRPQYLGENLSHYSSGVPHHGE 171
Query: 607 ASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQI 666
AS+ G S P E + + S S +G Q ++SQHHQ
Sbjct: 172 ASH---HGGSYLPHGPNPYSESFHH------SEASHLSGLQ----HDESQHHQ------- 211
Query: 667 QQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLS-HWAEEEQGHQTWDRHSHESQEGP 725
+ H+G W H +++ ++H G S H E H + + +
Sbjct: 212 -----VPHRG--WPHHHQVHHHGRSRHHEAHQHGKSPHHGETISPHSSVGSYQRGISDYH 264
Query: 726 CGTQDRRTHKDEQNHQRRDRQT-HEHEQSHQRRDRQTHED 764
H E +H T H + Q+H+ RD H+D
Sbjct: 265 SEYHQGDHHPSEYHHGDHPHHTQHHYHQTHRHRDYHQHQD 304
Score = 49.7 bits (117), Expect = 1e-05
Identities = 68/315 (21%), Positives = 105/315 (33%), Gaps = 55/315 (17%)
Query: 121 HRQRHEE--ERQNSHHSQPERQDGDSHHGQPERQD-----------RDSHHGQSEKQDR- 166
HR H HH Q G+SHH PE QD + HH ++ R
Sbjct: 32 HRPGHSRALHHYELHHHGVPHQRGESHH-PPEFQDFHDQALSSHVHQSHHHSEARNHGRA 90
Query: 167 ---------------DSHHSQPE------RQDRDSHHNQSE----RQDKDFSFDQSERQS 201
SH S E ++D HH+ S+ Q D + +
Sbjct: 91 HGPTGFGLAPSQGAVPSHRSYGEDYHDELQRDGRRHHDGSQYGGFHQQSDSHYHRGSHHG 150
Query: 202 QDSSSGKKVSHKSTS----GQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQAS 257
+ G+ +SH S+ G+A G + P + Y +S H++ S G
Sbjct: 151 RPQYLGENLSHYSSGVPHHGEASHHGGSYL------PHGPNPYSESFHHSEASHLSGLQH 204
Query: 258 HFNQTNQ--QKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQ 315
+Q +Q + + Q G+ + + G+S H+G+T S Q
Sbjct: 205 DESQHHQVPHRGWPHHHQVHHHGRSRH-HEAHQHGKSPHHGETISPHSSVGSYQRGISDY 263
Query: 316 SSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQ 375
S Y Q D S Y D + H+ + + YH Q + S Y +
Sbjct: 264 HSEYHQGDHH--PSEYHHGDHPHHTQHHYHQTHRHRDYHQHQDHHGAYHSSYLHGDYVQS 321
Query: 376 SSHYGQPDTQDQSSH 390
+S P T H
Sbjct: 322 TSQLSIPHTSRSLIH 336
Score = 45.4 bits (106), Expect = 2e-04
Identities = 63/276 (22%), Positives = 88/276 (31%), Gaps = 29/276 (10%)
Query: 70 DFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEER 129
DFH+ L V +H + ++HG G +Q P + E +R
Sbjct: 65 DFHDQALSSH--VHQSHHHSEARNHGRAHGPTGFGLAPSQGA-VPSHRSYGEDYHDELQR 121
Query: 130 QNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHH--SQPERQDRDSHHNQSER 187
H Q G H R SHHG+ + + H S SHH S
Sbjct: 122 DGRRHHDGS-QYGGFHQQSDSHYHRGSHHGRPQYLGENLSHYSSGVPHHGEASHHGGSYL 180
Query: 188 QDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHT 247
+ +S S+ SH S + Q H Q H+G+S H
Sbjct: 181 PHGPNPYSESFHHSE-------ASHLSGLQHDESQHHQVPHRGWPHHHQVHHHGRSRHH- 232
Query: 248 QQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHY 307
++ G++ H +T S +G Q S Y Q D YH+
Sbjct: 233 -EAHQHGKSPHHGETISPHS------------SVGSYQRGISDYHSEYHQGDHHPSEYHH 279
Query: 308 GQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHY 343
G Q HY QT R + H Q S Y
Sbjct: 280 GDHPHHTQ-HHYHQTHRH-RDYHQHQDHHGAYHSSY 313
Score = 42.4 bits (98), Expect = 0.002
Identities = 65/336 (19%), Positives = 112/336 (33%), Gaps = 60/336 (17%)
Query: 471 QSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQG 530
Q+S + + +++ + R S + +P HY + H+G P ++G
Sbjct: 3 QNSVPEKAQNEADTNNADRFFRSHSSPPHHRPGHSRALHHY-------ELHHHGVPHQRG 55
Query: 531 QSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGE 590
+S H + Q H Q SSH Q+ ++ ++G+ G + + G
Sbjct: 56 ESHHPPEF----QDFH-----DQALSSHVHQSHHHSEARNHGRA--HGPTGFGLAPSQGA 104
Query: 591 IQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWE 650
+ Y + Y ++ R GR G+ Q R S Q
Sbjct: 105 VPSHRSYGE--------DYHDELQRDGRRHHDGSQYGGFHQQSDSHYHRGSHHGRPQYLG 156
Query: 651 PEEDSQHHQHKLLAQIQQERPLCHKGRDW----QSCSSEQGHRQAQTRQSHGEGLSHWAE 706
E+ H+ + + H G + + SE H + SH GL H +
Sbjct: 157 --ENLSHYS----SGVPHHGEASHHGGSYLPHGPNPYSESFHH---SEASHLSGLQH--D 205
Query: 707 EEQGHQT----WDRH-------------SHESQEGPCGTQDRRTHKDEQNHQR--RDRQT 747
E Q HQ W H +H+ + P + H ++QR D +
Sbjct: 206 ESQHHQVPHRGWPHHHQVHHHGRSRHHEAHQHGKSPHHGETISPHSSVGSYQRGISDYHS 265
Query: 748 HEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQ 783
H+ H + + + Q QTH HQ
Sbjct: 266 EYHQGDHHPSEYHHGDHPHHTQHHYHQTHRHRDYHQ 301
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 75.1 bits (183), Expect = 2e-13
Identities = 77/260 (29%), Positives = 107/260 (41%), Gaps = 39/260 (15%)
Query: 292 SSHYGQTDRQDQSYH-YGQTDRQGQS------SHYSQTDRQGQSSHYSQPDRQGQS---- 340
S YGQ+ + QSY YG QG S Y QT +YS GQS
Sbjct: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63
Query: 341 --SHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQG------QSSHYGQPDTQDQSSHYG 392
S+ G ++K Y N QGQ + QG YGQ D+ DQ S Y
Sbjct: 64 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 123
Query: 393 Q-TDRQDQSSHYGQ---TERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDR---- 444
Q D+ S+Y Q + Q Q S++SQ + SH+ Q DR+ S YG+ +R
Sbjct: 124 QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENY---SHHTQDDRR-DVSRYGEDNRGYGG 179
Query: 445 -QGQNSHYGQTDRQGQSSHYGQT--DRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQ 501
QG G D+ G+ G + DR G + D ++ + D D + + Q
Sbjct: 180 SQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQ 239
Query: 502 PDGQGQSSHYGQTDRQGQSF 521
G+G S TD+ G+ F
Sbjct: 240 GLGEGVS-----TDQVGEFF 254
Score = 70.5 bits (171), Expect = 6e-12
Identities = 70/244 (28%), Positives = 96/244 (39%), Gaps = 31/244 (12%)
Query: 364 GSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQ 423
GS+ Q S YG P +Q YGQ + S YGQT +YS GQ
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQG----YGQASQS--YSGYGQTTDSSYGQNYSGYSSYGQ 58
Query: 424 GSH-----YGQTDRQGQSSHYGQP-DRQGQNSHYGQTDRQG------QSSHYGQTDRQGQ 471
YG + Q QSS+ QP + QGQ + + QG YGQ D Q
Sbjct: 59 SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQ 118
Query: 472 SSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQS---SHYGQTDRQGQSFHYGQPDR 528
S Y Q QG D+Q SY Q Q SH+ Q DR+ S YG+ +R
Sbjct: 119 QSGYDQ--HQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS-RYGEDNR 175
Query: 529 -----QGQSSHYSQMDRQGQSSHYGQT--DRQGQSSHYGQTDRQGQSYHYGQTDRQGQSS 581
QG D+ G+ G + DR G + G D ++ ++D ++
Sbjct: 176 GYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNT 235
Query: 582 HYIQ 585
++Q
Sbjct: 236 IFVQ 239
Score = 70.5 bits (171), Expect = 6e-12
Identities = 70/237 (29%), Positives = 96/237 (40%), Gaps = 27/237 (11%)
Query: 427 YGQTDRQGQS-SHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSS 485
YGQ+ + QS S YG P QG YGQ + S YGQT +YS GQS
Sbjct: 7 YGQSGGEQQSYSTYGNPGSQG----YGQASQS--YSGYGQTTDSSYGQNYSGYSSYGQSQ 60
Query: 486 H-----YGKIDRQDQSYHYGQP-DGQGQSSHYGQTDRQG-QSFHYGQPDRQGQSSHYSQM 538
YG + Q QS + QP + QGQ + + QG ++ Y QPD GQ Y Q
Sbjct: 61 SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD-YGQQDSYDQ- 118
Query: 539 DRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYF 598
+ G H G D Q S+Y D+Q SY Q Q +Y + + ++Y
Sbjct: 119 -QSGYDQHQGSYDEQ---SNY---DQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYG 171
Query: 599 QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDS 655
+ G + Q G GR G+ G + GH+ + P D+
Sbjct: 172 EDNRGYGGS----QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDA 224
Score = 68.9 bits (167), Expect = 2e-11
Identities = 76/231 (32%), Positives = 93/231 (40%), Gaps = 31/231 (13%)
Query: 388 SSHYGQTDRQDQS-SHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQG 446
S YGQ+ + QS S YG QG Y Q + G YGQT S YGQ
Sbjct: 4 SGSYGQSGGEQQSYSTYGNPGSQG----YGQASQSYSG--YGQT----TDSSYGQ--NYS 51
Query: 447 QNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQP-DKQGQ-------SSHYGKIDRQDQSYH 498
S YGQ+ + G S YG + Q QSS+ QP + QGQ S G+ DQ
Sbjct: 52 GYSSYGQS-QSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP-D 109
Query: 499 YGQPDGQGQSS----HYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQG 554
YGQ D Q S H G D Q Q Q S++SQ + SH+ Q DR+
Sbjct: 110 YGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENY---SHHTQDDRR- 165
Query: 555 QSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTR 605
S YG+ +R G R G TG G F+ G R
Sbjct: 166 DVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHR 216
Score = 62.8 bits (151), Expect = 1e-09
Identities = 55/186 (29%), Positives = 80/186 (43%), Gaps = 13/186 (6%)
Query: 508 SSHYGQTDRQGQSFH-YGQPDRQGQSSHYSQMDRQGQS--SHYGQTDRQGQSSHYGQTDR 564
S YGQ+ + QS+ YG P QG GQ+ S YGQ + G SS YGQ+ +
Sbjct: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQ-NYSGYSS-YGQS-Q 60
Query: 565 QGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQS-GRSGRLSQQT 623
G S YG + Q QSS+ Q + Q QN G++G R SY + G+ QQ+
Sbjct: 61 SGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 120
Query: 624 PGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQE--RPLCHKGRDWQS 681
GY + + + H + + S H Q + + Q+ R + G D +
Sbjct: 121 ----GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG 176
Query: 682 CSSEQG 687
QG
Sbjct: 177 YGGSQG 182
Score = 59.3 bits (142), Expect = 1e-08
Identities = 71/258 (27%), Positives = 100/258 (38%), Gaps = 41/258 (15%)
Query: 240 YGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQT-------DRQGQS 292
YGQS Q T G +Q Q S SY G + G + + G S
Sbjct: 7 YGQSGGEQQSYSTYGNPG--SQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
Query: 293 SHYGQTDRQDQSYHYGQT-DRQGQSSHYSQTDRQG-QSSHYSQPDRQGQSSHYGQMDRKG 350
YG + Q QS + Q + QGQ + + QG ++ Y QPD YGQ D
Sbjct: 65 QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD-------YGQQDSYD 117
Query: 351 QCYHYDQ--------TNRQGQGSHYSQPNRQGQS-----SHYGQPDTQDQSSHYGQTDRQ 397
Q YDQ +N Q YSQ + S SH+ Q D +D S YG+ +R
Sbjct: 118 QQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRD-VSRYGEDNRG 176
Query: 398 DQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQT--DRQGQSSHYGQPDRQGQNSHYGQTD 455
S G R G D+ G+G G + DR G + G D + ++D
Sbjct: 177 YGGSQGGGRGRGG-------YDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 229
Query: 456 RQGQSSHYGQTDRQGQSS 473
++ + Q +G S+
Sbjct: 230 NSDNNTIFVQGLGEGVST 247
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/228 (27%), Positives = 97/228 (42%), Gaps = 34/228 (14%)
Query: 200 QSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHF 259
Q+ DSS G+ S S+ GQ++ G+ + E Q S Y Q + Q GQ
Sbjct: 40 QTTDSSYGQNYSGYSSYGQSQ-SGYSQSYGGYENQKQSS-YSQQPYNNQ-----GQ---- 88
Query: 260 NQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSS----HYGQTDRQDQSYHYGQTDRQGQ 315
Q N + SGS G++ Q GQ D Q S H G D Q + Q Q
Sbjct: 89 -QQNMESSGSQGGRAPSYDQP-DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQ 146
Query: 316 SSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSH--------- 366
S++SQ + SH++Q DR+ S YG+ D +G Y Q +G+G +
Sbjct: 147 QSYHSQRENY---SHHTQDDRR-DVSRYGE-DNRG--YGGSQGGGRGRGGYDKDGRGPMT 199
Query: 367 -YSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSS 413
S +R G + G D ++ ++D D ++ + Q +G S+
Sbjct: 200 GSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVST 247
Score = 39.7 bits (91), Expect = 0.011
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 4/104 (3%)
Query: 86 YHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSH 145
Y +N+ + Q Q Q+ + G+ G + +++ S ++ D H
Sbjct: 67 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGR-APSYDQPDYGQQDSYDQQSGYDQH 125
Query: 146 HGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQD 189
G + Q S Q++ S+HSQ E SHH Q +R+D
Sbjct: 126 QGSYDEQSNYDQQHDSYSQNQQSYHSQRENY---SHHTQDDRRD 166
Score = 34.3 bits (77), Expect = 0.46
Identities = 45/214 (21%), Positives = 80/214 (37%), Gaps = 45/214 (21%)
Query: 125 HEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQ 184
+E ++Q+S+ QP ++ Q ++Q+ +S Q R + QP+ +DS+ Q
Sbjct: 70 YENQKQSSYSQQP-------YNNQGQQQNMESSGSQG---GRAPSYDQPDYGQQDSYDQQ 119
Query: 185 SERQDKDFSFDQSER--QSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQ 242
S S+D+ Q DS S + S+ S SH+ Q
Sbjct: 120 SGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENY------------------SHHTQ 161
Query: 243 SERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQE-------LGCGQTDRQGQSSHY 295
+R S + + N+ GS G R G + G DR G +
Sbjct: 162 DDRR--------DVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFG 213
Query: 296 GQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSS 329
G D ++ ++D ++ + Q +G S+
Sbjct: 214 GHRDYGPRTDADSESDNSDNNTIFVQGLGEGVST 247
Score = 32.0 bits (71), Expect = 2.3
Identities = 49/217 (22%), Positives = 86/217 (39%), Gaps = 58/217 (26%)
Query: 556 SSHYGQTDRQGQSYH-YGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSG 614
S YGQ+ + QSY YG QG Y Q+ Q + Y Q T+ + +Y
Sbjct: 4 SGSYGQSGGEQQSYSTYGNPGSQG----YGQAS----QSYSGYGQTTDSSYGQNY----- 50
Query: 615 RSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCH 674
GY + GQ QS SQ G +E ++ S + Q Q QQ+
Sbjct: 51 ------------SGYSSYGQS-QSGYSQSYGG--YENQKQSSYSQQPYNNQGQQQ----- 90
Query: 675 KGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTH 734
+ +S S+ G + + +G+ S+ +++ G+ D+H
Sbjct: 91 ---NMESSGSQGGRAPSYDQPDYGQQDSY--DQQSGY---DQHQGSY------------- 129
Query: 735 KDEQNHQRRDRQTHEHEQS--HQRRDRQTHEDKQNRQ 769
DEQ++ + ++ Q H +R+ +H + +R+
Sbjct: 130 -DEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRR 165
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 75.1 bits (183), Expect = 2e-13
Identities = 117/443 (26%), Positives = 164/443 (37%), Gaps = 72/443 (16%)
Query: 243 SERHTQQSETLGQASHFNQTNQ---QKSGSYCGQSERLGQELGCGQTDRQGQSSH--YGQ 297
S +TQQ+ T ++ Q Q Q+S GQ G T GQSS+ YGQ
Sbjct: 3 SNDYTQQA-TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQST-DTSGYGQSSYSSYGQ 60
Query: 298 TDR-----QDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQC 352
+ Q YG T G SS SQ+ QSS+ + SS G Q
Sbjct: 61 SQNTGYGTQSTPQGYGSTGGYG-SSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQS 119
Query: 353 YHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQS 412
Y Q GS+ QP+ GQ YGQ + + YGQ ++ + SS G
Sbjct: 120 SSYGQPQ---SGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG-------- 168
Query: 413 SHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQ--GQSSHYGQTDRQG 470
G G +YGQ D+ SS G YG D+ G S YGQ DR G
Sbjct: 169 ------GGGGGGGNYGQ-DQSSMSS------GGGSGGGYGNQDQSGGGGSGGYGQQDRGG 215
Query: 471 QSSHYSQPDKQGQSSHYGKIDRQDQSYH-YGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQ 529
+ S G Y +R Y G+ G+G G +DR G + +G P Q
Sbjct: 216 RGRGGSGGGGGGGGGGY---NRSSGGYEPRGRGGGRGGRGGMGGSDRGGFN-KFGGPRDQ 271
Query: 530 GQSSHYSQMDRQGQSSHYGQTDRQGQS-SHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQT 588
G S H S+ D ++ + Q + + +Q + Q + Y +T
Sbjct: 272 G-SRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRET 330
Query: 589 GEIQGQN--------------KYFQGTE----------GTRKASYVE--QSGRSGRLSQQ 622
G+++G+ +F G E TR+A + +GR GR
Sbjct: 331 GKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGG 390
Query: 623 TPGQEGYQNQGQGFQSRDSQQNG 645
G+ GY G G R +G
Sbjct: 391 PMGRGGYGGGGSGGGGRGGFPSG 413
Score = 49.7 bits (117), Expect = 1e-05
Identities = 70/280 (25%), Positives = 103/280 (36%), Gaps = 26/280 (9%)
Query: 164 QDRDSHHSQPERQDRDSHHNQSER-----QDKDFSFDQSERQSQDSSSGKKVSHKSTSGQ 218
Q SQP Q S ++QS Q S+ QS+ + S + + ST G
Sbjct: 23 QGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQ-GYGSTGGY 81
Query: 219 AKWQGHIFALNRCEKPIQDSH--YGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSER 276
Q + + Q S+ YGQ + S + G +S + Q +SGSY Q
Sbjct: 82 GSSQSSQSSYGQ-----QSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136
Query: 277 LGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQ-----GQSSHY 331
GQ+ GQ YGQ ++ + S G G +Y Q G Y
Sbjct: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSS--SGGGGGGGGGGNYGQDQSSMSSGGGSGGGY 194
Query: 332 SQPDRQ--GQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSS 389
D+ G S YGQ DR G+ G G Y++ + G G+ +
Sbjct: 195 GNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS--GGYEPRGRGGGRGGRG 252
Query: 390 HYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQ 429
G +DR + +G QG S H S+ D + + Q
Sbjct: 253 GMGGSDR-GGFNKFGGPRDQG-SRHDSEQDNSDNNTIFVQ 290
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 74.7 bits (182), Expect = 3e-13
Identities = 105/609 (17%), Positives = 229/609 (37%), Gaps = 54/609 (8%)
Query: 97 RTSQQERGQEGAQDCKFPGNTGRQHRQRHEE------ERQNSHHSQPERQ-DGDSHHGQP 149
R+ +E+G+ + T + H +RHE +R S+ ER+ + D +
Sbjct: 392 RSPMREKGRHDHE------RTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRD 445
Query: 150 ERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKK 209
R DR+ G+ + RD+ + R+ RDS + R+ +D+S D E + S +
Sbjct: 446 HRDDREPRDGRDRRDARDT---RDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTR 502
Query: 210 VSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGS 269
+H +G P + YG++ + S T + N++ +
Sbjct: 503 DAHDYRDR----EGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRND 558
Query: 270 YCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSS 329
G+S EL ++ + S Q D + +Y D S Y + DR +
Sbjct: 559 RMGRSRGRVPEL----PEKGSRGSRGSQIDSHSSNSNY--HDSWETRSSYPERDRYPERD 612
Query: 330 HYSQPDRQGQSSHYGQMDRKGQCYHYDQ-----TNRQGQGSHYSQPNRQGQSSHYGQPDT 384
+ Q +G+ DR+ DQ QG+ + R+ + D
Sbjct: 613 NRDQARDSSFERRHGERDRRDN-RERDQRPSSPIRHQGRNDELERDERREERRVDRVDDR 671
Query: 385 QDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDR 444
+D+ + + DR+ + + ER+ + + +R+ + + +R+ + + DR
Sbjct: 672 RDERAR--ERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729
Query: 445 QGQNSHYGQTDRQ-------GQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSY 497
+ + +R+ + + +R+ + + +++ + + +R+ Q
Sbjct: 730 DRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRD 789
Query: 498 HYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSS 557
+ G+ + R+ ++ G +R+ + + ++ + S + + S
Sbjct: 790 WEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSD 849
Query: 558 HYGQTDRQGQSYHY------GQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVE 611
Y D + + + Q R SH + + G + +++ + E +R+ E
Sbjct: 850 AYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 909
Query: 612 QSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEE--DSQHHQHKLLAQIQQE 669
+ + +Q E ++ + R GH E E D H ++K A+I Q+
Sbjct: 910 LKEKVSSVDKQREQTEILESS----RMRAQDIIGHHQSEDRETSDRAHDENKKKAKI-QK 964
Query: 670 RPLCHKGRD 678
+P+ K D
Sbjct: 965 KPIKKKKED 973
Score = 68.6 bits (166), Expect = 2e-11
Identities = 112/685 (16%), Positives = 257/685 (37%), Gaps = 57/685 (8%)
Query: 118 GRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRD---SHHGQSEKQDRDSHHSQPE 174
G++++++++ + + ++ + G Q E++D+ S GQ HHS
Sbjct: 277 GKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSS 336
Query: 175 RQDRD-SHHNQSERQDK--DFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRC 231
+ H+ S R+ + S+ ++ S+ SH +S Q K
Sbjct: 337 QSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRK----------- 385
Query: 232 EKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQ 291
+ P RH G+ H ++ S S+ + ER +E G+ DR+
Sbjct: 386 QSP---------PRHRSPMREKGRHDH-----ERTSQSHDRRHER--REDTRGKRDREKD 429
Query: 292 SSH---YGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDR 348
S Y Q + + + R G+ ++ R + S+ R + D
Sbjct: 430 SREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDT 489
Query: 349 KGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYG-QTE 407
K D + + + +R+G+ +H + ++S YG+ +++SS + E
Sbjct: 490 KES---RDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNE 546
Query: 408 RQGQSSHYSQMDRQGQ--GSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQ 465
+ +S + DR G+ G ++ + S Q D NS+Y D S Y +
Sbjct: 547 SRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYH--DSWETRSSYPE 604
Query: 466 TDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDG----QGQSSHYGQTDRQGQSF 521
DR + + Q +G+ DR+D +P QG++ + +R+ +
Sbjct: 605 RDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664
Query: 522 HYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSS 581
DR+ + + + DR+ + + +R+ + + +R+ + + +R+ +
Sbjct: 665 VDRVDDRRDERAR--ERDRERERDRERERERERERDREREKERELERERAREREREREKE 722
Query: 582 HYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDS 641
+ + + + K E+ R ++ + + + + + RD
Sbjct: 723 RDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDK 782
Query: 642 QQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGL 701
++ + WE ++ + + + +I+++R + +S + RQS
Sbjct: 783 ERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRR 842
Query: 702 SHWAEEE---QGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRD 758
H + + G ++H SQ + + + +H DRQ E+ +
Sbjct: 843 EHSPDSDAYNSGDDKNEKHRLLSQV----VRPQESRSLSPSHLTEDRQGRWKEEDRKPER 898
Query: 759 RQTHEDKQNRQRRDRQTHEDEQNHQ 783
+++ + ++ +++ + D+Q Q
Sbjct: 899 KESSRRYEEQELKEKVSSVDKQREQ 923
Score = 62.0 bits (149), Expect = 2e-09
Identities = 89/469 (18%), Positives = 187/469 (39%), Gaps = 45/469 (9%)
Query: 328 SSHYSQPDR-QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQ-----SSHYGQ 381
S S P R Q H M KG+ + +++T++ H + + +G+ S +
Sbjct: 376 SHSLSSPQRKQSPPRHRSPMREKGR-HDHERTSQSHDRRHERREDTRGKRDREKDSREER 434
Query: 382 PDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQ 441
QDQSS + R D+ G+ R + + DR+ D + +
Sbjct: 435 EYEQDQSS--SRDHRDDREPRDGRDRRDARDTR----DRRELRDSRDMRDSREMRDY--- 485
Query: 442 PDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKID-RQDQSYHYG 500
R + S + R + +H DR+G+ +H + +S YG+ R++ S
Sbjct: 486 -SRDTKESRDPRDSRSTRDAH-DYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 543
Query: 501 QPDGQGQSSHYGQTDRQGQSFHYGQ----PDRQGQSSHYSQMDRQGQSSHYGQTDRQGQS 556
+ + + +S + DR G+S G+ P++ + S SQ+D +S+Y D
Sbjct: 544 RNESRNESRSEIRNDRMGRS--RGRVPELPEKGSRGSRGSQIDSHSSNSNYH--DSWETR 599
Query: 557 SHYGQTDRQGQSYHYGQTDRQGQS-SHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGR 615
S Y + DR Y + D + Q+ + + GE +++ R +S + GR
Sbjct: 600 SSYPERDR------YPERDNRDQARDSSFERRHGE---RDRRDNRERDQRPSSPIRHQGR 650
Query: 616 SGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHK 675
+ L + +E ++ + +++ + E + + + + ++ER L
Sbjct: 651 NDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKEREL--- 707
Query: 676 GRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHK 735
+ + + R+ + + H E E+ + DR +E ++R +
Sbjct: 708 --ERERAREREREREKERDRERDRDRDHDRERERERER-DREKERERERE--ERERERER 762
Query: 736 DEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
+ + + R+R+ + + R+RQ + +++ R DR+ +E R
Sbjct: 763 ERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDR 811
Score = 57.8 bits (138), Expect = 4e-08
Identities = 128/722 (17%), Positives = 265/722 (36%), Gaps = 97/722 (13%)
Query: 131 NSHHSQPERQDGDSHHGQP-ERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQD 189
+++ PER GD +RQD D+ E Q R++ S + S E++D
Sbjct: 72 SNYRRSPERPTGDLRERMKNKRQDVDT-----EPQKRNTEESSSPVRKESSRGRHREKED 126
Query: 190 KDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQG-HIFALNRCEKPIQDSHYGQSERHTQ 248
+ +++ +++ + S +G + H +L + IQ + + +
Sbjct: 127 IKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENME 186
Query: 249 QSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYG 308
+ E + + + + S S L + + +SS + DR+ +
Sbjct: 187 KREEIIIKK---EVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSP 243
Query: 309 QTDRQGQSSHYSQTDRQGQSS-------------------HYSQPDRQGQSSHYGQ---M 346
D+Q ++S +Q+ ++G + Y DR + + G+
Sbjct: 244 LLDQQ-RNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGR 302
Query: 347 DRKGQCYHYDQ---TNRQGQ------GSHYSQPNRQGQSSHYGQPDTQDQ---SSHYGQT 394
D + Q D+ T+ GQ H+S ++ G S P + + S Y +T
Sbjct: 303 DFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRT 362
Query: 395 -------DRQDQSSHYGQTERQGQSS--HYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQ 445
SH + ++ QS H S M +G+ H +T + H + D +
Sbjct: 363 LTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHE-RTSQSHDRRHERREDTR 421
Query: 446 GQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQ 505
G+ DR+ S + ++ SS + D++ + + D +D D +
Sbjct: 422 GKR------DREKDSREEREYEQDQSSSRDHRDDREPRDGR-DRRDARDTRDRRELRDSR 474
Query: 506 GQSSHYGQTDRQGQSFHYGQP-DRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDR 564
D + P D + + DR+G+ +H + +S YG+
Sbjct: 475 DMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHL 534
Query: 565 QGQSYHYGQTDRQGQSSHYIQSQT-----GEIQGQ-----NKYFQGTEGTRKASYVEQSG 614
+ +S +T+ + +S + +S+ G +G+ K +G+ G++ S+ S
Sbjct: 535 REES---SRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSN 591
Query: 615 R--SGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPL 672
S P ++ Y + Q+RDS D++ + P+
Sbjct: 592 YHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQR------PSSPI 645
Query: 673 CHKGRDWQSCSSEQ----------GHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQ 722
H+GR+ + E+ R + R+ E E + + DR + +
Sbjct: 646 RHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKER 705
Query: 723 EGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNH 782
E ++R ++ + + RDR+ + R+R+ D++ + R+R+ E E+
Sbjct: 706 ELE---RERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERER 762
Query: 783 QR 784
+R
Sbjct: 763 ER 764
Score = 43.5 bits (101), Expect = 8e-04
Identities = 38/187 (20%), Positives = 71/187 (37%), Gaps = 31/187 (16%)
Query: 90 DNKSHGGRTSQQERGQE-GAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQ 148
D++SH R S E ++ ++ F Q R R+E +R+
Sbjct: 1269 DSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRER----------------- 1311
Query: 149 PERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGK 208
ER+ RD+ + + DRD+ P +DRD + +++D D + + S
Sbjct: 1312 -ERERRDT---RQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSV 1367
Query: 209 KVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQS---------ETLGQASHF 259
+ + I ++ RCE ++ H E ++ S + LG F
Sbjct: 1368 ERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGF 1427
Query: 260 NQTNQQK 266
+TN+ +
Sbjct: 1428 EETNKSE 1434
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/316 (16%), Positives = 115/316 (36%), Gaps = 44/316 (13%)
Query: 90 DNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQP 149
D + R ++ER +E ++ + R+ + E ER+ +
Sbjct: 680 DRERERDRERERERERERDREREKERELERERAREREREREKE---------------RD 724
Query: 150 ERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKK 209
+DRD H + +++R+ + ++R+ + ER+ + ER+ + +
Sbjct: 725 RERDRDRDHDRERERERERDREKEREREREERERERERE------RERERERERERERAR 778
Query: 210 VSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGS 269
K Q W +D G+ +R ++ E + + +++KS
Sbjct: 779 ERDKERERQRDW--------------EDKDKGRDDRREKREEIREDRNPRDGHDERKSKK 824
Query: 270 -YCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHY------GQTDRQGQSSHYSQT 322
Y + ++ + + S Y D +++ + Q R SH ++
Sbjct: 825 RYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTE- 883
Query: 323 DRQGQ-SSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQ 381
DRQG+ +P+R+ S Y + + K + D+ Q + S+ Q H+
Sbjct: 884 DRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQS 943
Query: 382 PDTQDQSSHYGQTDRQ 397
D + + + ++
Sbjct: 944 EDRETSDRAHDENKKK 959
Score = 38.5 bits (88), Expect = 0.024
Identities = 32/147 (21%), Positives = 56/147 (38%), Gaps = 22/147 (14%)
Query: 653 EDSQHHQ---HKLLAQIQQERP-LCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEE 708
ED+QH + K + + R H +S S++ HR + L + +
Sbjct: 1176 EDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDR 1235
Query: 709 QGHQTWD------------RHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSH-- 754
+ ++ + + S+ QD R+H ++ DRQ H S
Sbjct: 1236 EKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDS 1295
Query: 755 ----QRRDRQTHEDKQNRQRRDRQTHE 777
Q RDR H+ ++ R+RRD + E
Sbjct: 1296 RDRLQERDRYEHDRERERERRDTRQRE 1322
Score = 37.0 bits (84), Expect = 0.071
Identities = 36/176 (20%), Positives = 65/176 (36%), Gaps = 38/176 (21%)
Query: 636 FQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQ 695
F + DS + H+ + ++ H + Q +P+ K SS G ++ +
Sbjct: 1151 FANEDSHRKCHRTRVEKVETPH---VTIEDAQHRKPMDQKR------SSSLGSNRSN--R 1199
Query: 696 SHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQ----------------- 738
SH G + H++ D S + G++DR K +
Sbjct: 1200 SHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEP 1259
Query: 739 ----NHQRRDRQTHEHEQSHQRRDRQTH------EDKQNRQRRDRQTHEDEQNHQR 784
+ R+D ++H +S DRQ H + + Q RDR H+ E+ +R
Sbjct: 1260 SRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERER 1315
Score = 33.9 bits (76), Expect = 0.60
Identities = 38/176 (21%), Positives = 62/176 (35%), Gaps = 13/176 (7%)
Query: 613 SGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPL 672
S RS R T G+ + +S D Q +V S+ + +I ER
Sbjct: 1194 SNRSNR--SHTSGRLRSPSNDSAHRSGDDQSGRKRVLH--SGSRDREKTKSLEITGER-- 1247
Query: 673 CHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRR 732
K R Q E + RQ S + E Q R +DR
Sbjct: 1248 --KSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY 1305
Query: 733 THKDEQNHQRRDRQTHEHEQSHQR-----RDRQTHEDKQNRQRRDRQTHEDEQNHQ 783
H E+ +RRD + E ++ + RDR +++ + RD++ D + +
Sbjct: 1306 EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERER 1361
>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
sapiens]
Length = 1067
Score = 72.8 bits (177), Expect = 1e-12
Identities = 113/549 (20%), Positives = 191/549 (34%), Gaps = 65/549 (11%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHE---EERQNSHHSQPERQDGD 143
H LD S GGR+ G + + G+ HR E E R SH + D
Sbjct: 516 HSLDANS-GGRSPDTHSGGHSSSSNSY----GQSHRYGGEGRYEYRGRSHDAHSGGCSAD 570
Query: 144 SHHGQPERQDRDSHHG--------QSEKQDRDSHHSQPERQDRDSHHNQ-SERQDKDFSF 194
++ G + + + +G + D +S P + S R +
Sbjct: 571 AYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRY 630
Query: 195 DQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLG 254
++ +S D++SG + S A GH + Q + YG R+ + L
Sbjct: 631 EEYRGRSLDANSGGR------SPDAYSGGH-------DSSGQSNCYGGGGRYEEYRGRLL 677
Query: 255 QASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQG 314
A+ ++ SG + S+ G + +G S R +Y G D
Sbjct: 678 DANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGH-DSSS 736
Query: 315 QSSHYSQTDRQGQSSHYSQ-PDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQ 373
QS HY R ++ + PD ++ G D + + Y G G Y + +
Sbjct: 737 QSDHYGGGGRSLDANSSGRLPD-----AYSGGHDSSSRSHRY------GGGGRYEEYRGR 785
Query: 374 GQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQ 433
++ G S + + R D G+ E H + G + R
Sbjct: 786 SLDANSGGRSPNAYSGGHNSSSRNDPCRGGGRYEEN--RGHSLDANSGGHSPNAYSGGRD 843
Query: 434 GQSSHYGQPDRQGQNSHYGQTDRQGQSSHY-GQTDRQGQSSHYSQPDKQGQSSHYGKIDR 492
S+ Y + R G HY + + +H G++ HY++ +G+ S
Sbjct: 844 SSSNSYDRSHRYGGGGHYEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSF------ 897
Query: 493 QDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDR 552
S YG+ D G+ Y + + + + G ++ + + R G Y +
Sbjct: 898 ---SNSYGRSDHYGRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGRSHRYGGGGRYEEYRG 954
Query: 553 QGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQ 612
+H G D +S YG +DR G HY + Q G + + G SY
Sbjct: 955 PSPDAHSGGRDSSIKS--YGLSDRYGGGGHYEEYQ-GSLPDA---YSGDHDRSSNSY--- 1005
Query: 613 SGRSGRLSQ 621
GRS R S+
Sbjct: 1006 -GRSDRYSR 1013
Score = 65.5 bits (158), Expect = 2e-10
Identities = 132/613 (21%), Positives = 212/613 (34%), Gaps = 82/613 (13%)
Query: 175 RQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKP 234
R + +++S+R ++ +++ +S D+ SG + S ++ GQ+ H R E+
Sbjct: 370 RSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSH---HYGGEGRYEEY 426
Query: 235 IQDSHYGQSERHTQQSETLGQASHFNQTNQQKS--GSYCGQSERLGQELGCGQTDRQGQS 292
SH +S + + + G++ S CG R + G G
Sbjct: 427 RGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGC 486
Query: 293 SHYGQTDRQDQSYHYGQTDRQGQSSHYSQ-------TDRQGQSSHYSQPDRQGQSSHYGQ 345
S + D S +DR G HY + + G+S S+ YGQ
Sbjct: 487 SPEAYSGGHDNS---SWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQ 543
Query: 346 MDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYG-------QTDRQD 398
R G Y+ R SH + ++ G D+ QS+ YG R
Sbjct: 544 SHRYGGEGRYEYRGR----SHDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSL 599
Query: 399 QSSHYGQTERQGQSSHYSQ--MDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDR 456
++ G++ H S R G G Y + + ++ G + +++ G D
Sbjct: 600 DANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSG---GRSPDAYSGGHDS 656
Query: 457 QGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDR 516
GQS+ YG R + +G+ R +Y G D QS+ YG R
Sbjct: 657 SGQSNCYGGGGR--------YEEYRGRLLDANSGGRSPDAYSGGH-DSSSQSNRYGGGGR 707
Query: 517 QGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDR 576
+ +G S + R + G D QS HYG R + G+
Sbjct: 708 --------YEEYRGHSLDANSGGRSPDTYSRGH-DSSSQSDHYGGGGRSLDANSSGRLPD 758
Query: 577 QGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGF 636
H S++ G +Y E R S SG GR G G
Sbjct: 759 AYSGGHDSSSRSHRYGGGGRY----EEYRGRSLDANSG--GRSPNAYSG-------GHNS 805
Query: 637 QSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHK-GRDWQSCSSEQGHRQAQTRQ 695
SR+ G +E ++ H L A P + GRD S S ++ HR
Sbjct: 806 SSRNDPCRGGGRYE-----ENRGHSLDANSGGHSPNAYSGGRDSSSNSYDRSHRYG---- 856
Query: 696 SHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQ 755
G H+ EE ++ D HS G H E + RD ++ + +S
Sbjct: 857 ----GGGHY--EEYRGRSHDTHS----RGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDH 906
Query: 756 RRDRQTHEDKQNR 768
+E+ Q R
Sbjct: 907 YGRGGCYEEYQGR 919
Score = 60.5 bits (145), Expect = 6e-09
Identities = 111/528 (21%), Positives = 182/528 (34%), Gaps = 79/528 (14%)
Query: 299 DRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYG----QMDRKGQCYH 354
D ++Y G R S+ YS++DR G+ Y + + +H G + GQ +H
Sbjct: 360 DHSPKAYSGG---RSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHH 416
Query: 355 YDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYG----QTERQG 410
Y R + S R G S + ++ G D S G E QG
Sbjct: 417 YGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQG 476
Query: 411 QS-----------------SHYSQMDRQGQGSHYGQTDRQGQSSHYG--QPDRQGQNSHY 451
+S + S DR G G HY + ++ G PD H
Sbjct: 477 RSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTH-SGGHS 535
Query: 452 GQTDRQGQSSHYGQTDRQGQ--SSHYSQPDKQGQSSHYGKIDRQDQSYHYG--------- 500
++ GQS YG R SH + ++ G D QS YG
Sbjct: 536 SSSNSYGQSHRYGGEGRYEYRGRSHDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYR 595
Query: 501 ------QPDGQGQSSHYGQTDRQGQSFHYGQPDR----QGQSSHYSQMDRQGQSSHYGQT 550
G+ +++ G D S YG R +G+S + R ++ G
Sbjct: 596 GRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSGGR-SPDAYSGGH 654
Query: 551 DRQGQSSHYGQTDRQGQ-------SYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEG 603
D GQS+ YG R + + G++ H SQ+ G +Y +
Sbjct: 655 DSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGH 714
Query: 604 TRKASYVEQSGRS-GRLSQQTPGQEGYQNQGQGFQSRDSQQNGH--QVWEPEEDSQHHQH 660
+ A+ GRS S+ + G G +S D+ +G + DS H
Sbjct: 715 SLDAN---SGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSH 771
Query: 661 KLLAQIQQERPLCHKGRD------WQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTW 714
+ + E ++GR +S ++ G + +R G + EE +GH
Sbjct: 772 RYGGGGRYEE---YRGRSLDANSGGRSPNAYSGGHNSSSRNDPCRGGGRY-EENRGHSLD 827
Query: 715 DRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTH 762
S G +D ++ +++H+ H + ++ R TH
Sbjct: 828 ANSGGHSPNAYSGGRDSSSNSYDRSHRYGG---GGHYEEYRGRSHDTH 872
Score = 35.8 bits (81), Expect = 0.16
Identities = 71/342 (20%), Positives = 117/342 (34%), Gaps = 59/342 (17%)
Query: 438 HYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQ-----------GQSSH 486
H PD + Q +G+ Y TD + S Y +P K G
Sbjct: 266 HSSVPDYRPLRGDGNQNGYRGRDHEY--TDHPSKGS-YREPLKSYGGPCGAAPVWGTPPS 322
Query: 487 YGKIDRQDQSYHYGQPDG--QGQSSH---------YGQTDRQGQSFHYGQPDRQGQSSHY 535
YG R ++ Y PD +G+SS Y + D +++ G R S+ Y
Sbjct: 323 YGGGCRYEE-YQGNSPDACSEGRSSEALPVVLPDAYSR-DHSPKAYSGG---RSSSSNGY 377
Query: 536 SQMDRQGQSSHYGQTDRQGQSSHYG----QTDRQGQSYHYGQTDRQGQ---SSHYIQS-- 586
S+ DR G+ Y + + +H G ++ GQS+HYG R + SH +S
Sbjct: 378 SRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGG 437
Query: 587 QTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGH 646
++ + + + G +S G ++ G+ N G S + +
Sbjct: 438 RSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGGHDN 497
Query: 647 QVWEPE-----EDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGL 701
W ++ H L A P H G GH + + S+G+
Sbjct: 498 SSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSG----------GH--SSSSNSYGQSH 545
Query: 702 SHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRR 743
+ E G + SH++ G C D + R
Sbjct: 546 RYGGE---GRYEYRGRSHDAHSGGCSADAYSGGHDSSSQSNR 584
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 71.6 bits (174), Expect = 3e-12
Identities = 70/234 (29%), Positives = 96/234 (41%), Gaps = 24/234 (10%)
Query: 427 YGQTDRQGQS-SHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQS- 484
YGQ+ + QS S YG P QG YGQ + S YGQT +YS GQS
Sbjct: 7 YGQSGGEQQSYSTYGNPGSQG----YGQASQS--YSGYGQTTDSSYGQNYSGYSSYGQSY 60
Query: 485 -SHYGKIDRQDQSYHYGQP-DGQGQSSHYGQTDRQG-QSFHYGQPDRQGQSSHYSQMDRQ 541
YG + Q QS + QP + QGQ + + QG ++ Y QPD GQ Y Q +
Sbjct: 61 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD-YGQQDSYDQ--QS 117
Query: 542 GQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGT 601
G H G D Q S+Y D+Q SY Q Q +Y + + ++Y +
Sbjct: 118 GYDQHQGSYDEQ---SNY---DQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDN 171
Query: 602 EGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDS 655
G + Q G GR G+ G + GH+ + P D+
Sbjct: 172 RGYGGS----QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDA 221
Score = 70.5 bits (171), Expect = 6e-12
Identities = 74/246 (30%), Positives = 98/246 (39%), Gaps = 41/246 (16%)
Query: 364 GSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQ 423
GS+ Q S YG P +Q YGQ + S YGQT +YS GQ
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQG----YGQASQS--YSGYGQTTDSSYGQNYSGYSSYGQ 58
Query: 424 G--SHYGQTDRQGQSSHYGQP-DRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDK 480
YG + Q QSS+ QP + QGQ + + QG G++ Y QPD
Sbjct: 59 SYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQG-----------GRAPSYDQPD- 106
Query: 481 QGQSSHYGKIDRQDQSYHYGQPDGQ-GQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMD 539
YG+ D DQ Y Q G + S+Y D+Q S+ Q Q S++SQ +
Sbjct: 107 ------YGQQDSYDQQSGYDQHQGSYDEQSNY---DQQHDSYS------QNQQSYHSQRE 151
Query: 540 RQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQ 599
SH+ Q DR+ S YG+ +R G R G TG G F+
Sbjct: 152 NY---SHHTQDDRR-DVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK 207
Query: 600 GTEGTR 605
G R
Sbjct: 208 NFGGHR 213
Score = 68.6 bits (166), Expect = 2e-11
Identities = 75/261 (28%), Positives = 102/261 (39%), Gaps = 44/261 (16%)
Query: 292 SSHYGQTDRQDQSYH-YGQTDRQGQS------SHYSQTDRQGQSSHYSQPDRQGQS---S 341
S YGQ+ + QSY YG QG S Y QT +YS GQS S
Sbjct: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
Query: 342 HYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQG------QSSHYGQPDTQDQSS----HY 391
+ G ++K Y N QGQ + QG YGQ D+ DQ S H
Sbjct: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQ 123
Query: 392 GQTDRQD----QSSHYGQTERQGQS-----SHYSQMDRQGQGSHYGQTDRQGQSSHYGQP 442
G D Q Q Y Q ++ S SH++Q DR+ S YG+ +R G
Sbjct: 124 GSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRR-DVSRYGEDNR-------GYG 175
Query: 443 DRQGQNSHYGQTDRQGQSSHYGQT--DRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYG 500
QG G D+ G+ G + DR G + D ++ + D D + +
Sbjct: 176 GSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFV 235
Query: 501 QPDGQGQSSHYGQTDRQGQSF 521
Q G+G S TD+ G+ F
Sbjct: 236 QGLGEGVS-----TDQVGEFF 251
Score = 62.4 bits (150), Expect = 2e-09
Identities = 53/186 (28%), Positives = 76/186 (40%), Gaps = 16/186 (8%)
Query: 508 SSHYGQTDRQGQSFH-YGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQG 566
S YGQ+ + QS+ YG P QG Y Q + S YGQT +Y G
Sbjct: 4 SGSYGQSGGEQQSYSTYGNPGSQG----YGQASQS--YSGYGQTTDSSYGQNYSGYSSYG 57
Query: 567 QSYH--YGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQS-GRSGRLSQQT 623
QSY YG + Q QSS+ Q + Q QN G++G R SY + G+ QQ+
Sbjct: 58 QSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQS 117
Query: 624 PGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQE--RPLCHKGRDWQS 681
GY + + + H + + S H Q + + Q+ R + G D +
Sbjct: 118 ----GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRG 173
Query: 682 CSSEQG 687
QG
Sbjct: 174 YGGSQG 179
Score = 57.4 bits (137), Expect = 5e-08
Identities = 71/264 (26%), Positives = 101/264 (38%), Gaps = 44/264 (16%)
Query: 240 YGQSERHTQQSETLGQ--ASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQ 297
YGQS Q T G + + Q +Q SG GQ + Q S YG
Sbjct: 7 YGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSYGG 66
Query: 298 TDRQDQSYHYGQT-DRQGQSSH-------------YSQTDRQGQSSHYSQPDRQGQSSHY 343
+ Q QS + Q + QGQ + Y Q D GQ Y Q + G H
Sbjct: 67 YENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD-YGQQDSYDQ--QSGYDQHQ 123
Query: 344 GQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHY 403
G D +Q+N Q YS Q Q S++ Q ++ SH+ Q DR+D S Y
Sbjct: 124 GSYD--------EQSNYDQQHDSYS----QNQQSYHSQ---RENYSHHTQDDRRD-VSRY 167
Query: 404 GQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQP--DRQGQNSHYGQTDRQGQSS 461
G+ R S QG G G D+ G+ G DR G + G D ++
Sbjct: 168 GEDNRGYGGS-------QGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTD 220
Query: 462 HYGQTDRQGQSSHYSQPDKQGQSS 485
++D ++ + Q +G S+
Sbjct: 221 ADSESDNSDNNTIFVQGLGEGVST 244
Score = 50.4 bits (119), Expect = 6e-06
Identities = 56/220 (25%), Positives = 88/220 (40%), Gaps = 21/220 (9%)
Query: 200 QSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHY---GQSERHTQQSETLGQA 256
Q+ DSS G+ S S+ GQ+ Q + N+ + Y GQ + G+A
Sbjct: 40 QTTDSSYGQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRA 99
Query: 257 SHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQS 316
++Q + + SY QS G QG D+Q SY Q Q
Sbjct: 100 PSYDQPDYGQQDSYDQQS---------GYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQR 150
Query: 317 ---SHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQ 373
SH++Q DR+ S Y + +R S G R G YD+ R G + S +R
Sbjct: 151 ENYSHHTQDDRR-DVSRYGEDNRGYGGSQGGGRGRGG----YDKDGR-GPMTGSSGGDRG 204
Query: 374 GQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSS 413
G + G D ++ ++D D ++ + Q +G S+
Sbjct: 205 GFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVST 244
Score = 39.7 bits (91), Expect = 0.011
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 4/104 (3%)
Query: 86 YHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSH 145
Y +N+ + Q Q Q+ + G+ G + +++ S ++ D H
Sbjct: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGR-APSYDQPDYGQQDSYDQQSGYDQH 122
Query: 146 HGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQD 189
G + Q S Q++ S+HSQ E SHH Q +R+D
Sbjct: 123 QGSYDEQSNYDQQHDSYSQNQQSYHSQRENY---SHHTQDDRRD 163
Score = 36.6 bits (83), Expect = 0.092
Identities = 51/243 (20%), Positives = 91/243 (37%), Gaps = 46/243 (18%)
Query: 96 GRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRD 155
G+T+ GQ + + G + Q +E ++Q+S+ QP ++ Q ++Q+ +
Sbjct: 39 GQTTDSSYGQNYSGYSSY-GQSYSQSYGGYENQKQSSYSQQP-------YNNQGQQQNME 90
Query: 156 SHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSER--QSQDSSSGKKVSHK 213
S Q R + QP+ +DS+ QS S+D+ Q DS S + S+
Sbjct: 91 SSGSQG---GRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYH 147
Query: 214 STSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQ 273
S SH+ Q +R S + + N+ GS G
Sbjct: 148 SQRENY------------------SHHTQDDRR--------DVSRYGEDNRGYGGSQGGG 181
Query: 274 SERLGQE-------LGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQG 326
R G + G DR G + G D ++ ++D ++ + Q +G
Sbjct: 182 RGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEG 241
Query: 327 QSS 329
S+
Sbjct: 242 VST 244
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 71.2 bits (173), Expect = 3e-12
Identities = 105/651 (16%), Positives = 247/651 (37%), Gaps = 78/651 (11%)
Query: 180 SHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEK-----P 234
S + + ++ D+ D+ ++++ +S S T+ HI +LN EK P
Sbjct: 461 SEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMT-HIMSLNSNEKSLKLSP 519
Query: 235 IQDSHYGQSERHTQQSETLGQ---ASHFNQTNQQKSGSYCGQSERLG------------- 278
+Q Q+ Q L + + + + ++ K G C Q G
Sbjct: 520 VQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAF 579
Query: 279 ---------QELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSS 329
++ G + G + + ++ H G+ ++ S TD+ S
Sbjct: 580 SDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSD-DLTDKAEVSE 638
Query: 330 HYSQPDRQGQSSHYGQMD------RKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPD 383
++ + + G+ D G + D+ +G+ + +G+ G+ +
Sbjct: 639 GKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGE-----KDKGRGEMERPGEGE 693
Query: 384 TQ-DQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQP 442
+ + + + D ++Q + E+ Q +M+ G+ H + +G +
Sbjct: 694 KELAEKEEWKKRDGEEQEQK--EREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEK 751
Query: 443 DRQGQNSHYGQT---DRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHY 499
+ +G+ G+ +R+ + + +R G+ + QG+ R ++
Sbjct: 752 EGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEG 811
Query: 500 GQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHY 559
G+ +G G+ + + + + + +G+ + +G+ G+ + +G+
Sbjct: 812 GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE----GKGEEEGEE--- 864
Query: 560 GQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGT---EGTRKASYVEQSGRS 616
G+ + +G+ G+ + + + + GE +G+ + +G EG + E G+
Sbjct: 865 GEGEEEGEE---GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKG 921
Query: 617 GRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQV---WEPEEDSQHHQHKLLAQIQQERPLC 673
++ G EG + +G+G + D + G + WE EE+ + + + + E
Sbjct: 922 EEEGEEGEG-EGEEEEGEG-EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEG-- 977
Query: 674 HKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPC-GTQDRR 732
+G E+G + + + EG EE+G + EG G +
Sbjct: 978 -EGEG----EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEG 1032
Query: 733 THKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQ 783
++E+ + + + E E RR+R+ E+++ + ++T E+E Q
Sbjct: 1033 EGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY---QETGEEENERQ 1080
Score = 59.3 bits (142), Expect = 1e-08
Identities = 62/443 (13%), Positives = 172/443 (38%), Gaps = 68/443 (15%)
Query: 119 RQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDR 178
++ Q H++ER E + G+ + +R++ + G+ K++ + + ER+
Sbjct: 713 KEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEG-KEEGEGEEVEGEREKE 771
Query: 179 DSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTS-GQAKWQGHIFALNRCEKPIQD 237
+ + ER K+ E+ ++ G+ ++ G+ K +G E+
Sbjct: 772 EGERKKEERAGKE------EKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE---- 821
Query: 238 SHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQ 297
G+ ER ++ E G+ ++ G +E G G+ + +G+
Sbjct: 822 ---GKGEREEEEEEGEGEEEEGEGEEEEGEGE---------EEEGEGKGEEEGEE----- 864
Query: 298 TDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSH-YGQMDRKGQCYHYD 356
G+ + +G+ + +G+ + + +G+ G+ + +G
Sbjct: 865 ----------GEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG------ 908
Query: 357 QTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYS 416
+G+G + +G+ G+ + G+ + +D G+ E + + +
Sbjct: 909 ----EGEG---EEEEGEGKGEEEGEEGEGEGEEEEGEGEGED-----GEGEGEEEEGEWE 956
Query: 417 QMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQ-NSHYGQTDRQGQSSHYGQTDRQGQSSHY 475
+ +G+G + + +G+ + +G+ + + +G+ G+ + +G+
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE 1016
Query: 476 SQPDKQG-----QSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHY---GQPD 527
+ + +G + G+ + ++ + +G+G+ + + + + + Y G+ +
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076
Query: 528 RQGQ-SSHYSQMDRQGQSSHYGQ 549
+ Q Y ++ + S YG+
Sbjct: 1077 NERQDGEEYKKVSKIKGSVKYGK 1099
Score = 53.1 bits (126), Expect = 1e-06
Identities = 54/410 (13%), Positives = 162/410 (39%), Gaps = 32/410 (7%)
Query: 100 QQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHG 159
++E+G + ++ + +H + EEE + E + + G+ +R+ G
Sbjct: 714 EREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEG 773
Query: 160 QSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQA 219
+ +K++R + E + + E + + + + + + G+ K +
Sbjct: 774 ERKKEERAGKEEKGEEEGDQGEGEEEETEGR----GEEKEEGGEVEGGEVEEGKGEREEE 829
Query: 220 KWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSER--- 276
+ +G + ++ G+ E + E G+ + ++ G G+ E
Sbjct: 830 EEEGE--GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE--GEEEEGEG 885
Query: 277 LGQELGCGQTDR---QGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQ 333
G+E G G+ + +G+ G+ + +++ G+ + +G+ + +G+
Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE-GKGEEEGEEGEGEGEEEEGEG----- 939
Query: 334 PDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQ 393
+G+ + +G+ ++ +G+G + +G+ G+ + ++ +
Sbjct: 940 ---EGEDGEGEGEEEEGE---WEGEEEEGEGEGEEEGEGEGEEGE-GEGEEEEGEGEGEE 992
Query: 394 TDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQT-DRQGQSSHYGQPDRQGQNSHYG 452
+ +++ G+ E +G+ + + + +G G+ + +G+ + + + G
Sbjct: 993 EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052
Query: 453 QTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQ-SSHYGKIDRQDQSYHYGQ 501
+ +R+ + + + +G+ + + + Q Y K+ + S YG+
Sbjct: 1053 EENRRNREE---EEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGK 1099
Score = 46.2 bits (108), Expect = 1e-04
Identities = 45/300 (15%), Positives = 111/300 (37%), Gaps = 40/300 (13%)
Query: 90 DNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQP 149
+ + G +E G+EG + G + EEE + +G+ G+
Sbjct: 848 EGEEEEGEGKGEEEGEEGEGE-----EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 902
Query: 150 ERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKK 209
E ++ G+ E++ + E + + + E + +D + E + +
Sbjct: 903 EGEEEGEGEGE-EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE------- 954
Query: 210 VSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGS 269
W+G E+ + + E ++ E G+ +++ G
Sbjct: 955 -----------WEGE-------EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996
Query: 270 YCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSS 329
G+ E G+E G G+ + + + G+ + ++ G+ + + + +++G+
Sbjct: 997 EEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE---GEGEEEEGEEEGEEREKEGEGE 1053
Query: 330 HYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSS 389
++ +R+ + G+ G ++ N + G Y + ++ S YG+ T + S
Sbjct: 1054 E-NRRNREEEEEEEGKYQETG-----EEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKS 1107
Score = 30.0 bits (66), Expect = 8.6
Identities = 23/116 (19%), Positives = 47/116 (40%), Gaps = 8/116 (6%)
Query: 95 GGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDR 154
G ++E G+E ++ + G R R EEE + + + ++ ERQD
Sbjct: 1030 GEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEEN-------ERQDG 1082
Query: 155 DSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFD-QSERQSQDSSSGKK 209
+ + S+ + + Q + + Q +++ QS+R ++ SG K
Sbjct: 1083 EEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPSGSK 1138
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 66.6 bits (161), Expect = 8e-11
Identities = 84/418 (20%), Positives = 141/418 (33%), Gaps = 22/418 (5%)
Query: 144 SHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQD 203
S + P + +GQ R+ +S E R +NQ+ + + S QS +
Sbjct: 231 SDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRS 290
Query: 204 SSSGKKVSHKSTSGQAKWQGHIFALNRCEKPI--QDSHYGQSERHTQ-----QSETLGQA 256
S +K +H + + H A +R K I Q + QS H++ QS T +
Sbjct: 291 RSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRG 350
Query: 257 SHFN---QTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQ-DQSYHYGQT-- 310
N ++++S S+ S + G ++ S G ++Q D S
Sbjct: 351 RSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA 410
Query: 311 -DRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQ 369
DR S Y DR S D S Y DR N+ S
Sbjct: 411 RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRS----RSRSPNKARDHSRSRS 466
Query: 370 PNRQGQSSHYGQPDTQDQSSHYG--QTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHY 427
PN+ S P + S G +R + S ERQ + S S +R + S
Sbjct: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS 526
Query: 428 GQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHY 487
+RQ + S +R S +R+ + S +R + + P K+ +
Sbjct: 527 PSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRR--RWRSPSKERERRQS 584
Query: 488 GKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSS 545
+ P+ Q S + ++ P ++G S ++ S
Sbjct: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPS 642
Score = 62.4 bits (150), Expect = 2e-09
Identities = 97/485 (20%), Positives = 178/485 (36%), Gaps = 40/485 (8%)
Query: 324 RQGQSSHYSQPDRQGQSSH---YGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQG--QSSH 378
R G +S P Q + S YG+ R D R Y P G +SS
Sbjct: 151 RPGMASRVRTPTSQQKGSRGKSYGR-PRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSE 209
Query: 379 YG-QPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSS 437
P T + G ++ + + R+ +S Y QM + Y T+ +
Sbjct: 210 LAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKS--YGQMIIPSREKSYSPTEMSSRVK 267
Query: 438 HYGQPDRQGQNSHYGQT--DRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQ 495
Y Q + + + Q+ R+ +S +T + +S + + + +S I Q
Sbjct: 268 SYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMG 327
Query: 496 SYHYGQPDGQGQSSHYGQTDRQGQSFHYGQ-PDRQGQSSHY----SQMDRQGQSSHYGQT 550
+ + +G+S + +T R+G+S ++ + P ++ SH + D +G SS ++
Sbjct: 328 RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKES 387
Query: 551 DRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKY--FQGTEGTRKAS 608
R S Q D DR S Y + NK + KA
Sbjct: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
Query: 609 YVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGH-QVWEPEEDSQHHQHKLLAQIQ 667
+S + + + + + + S++ H Q+ P ++ H + + ++ +
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
Query: 668 QERPLCHKGRDWQSCSSEQGHRQA-------QTRQSHGEGLSHWAEEEQGHQTWDRHSHE 720
Q C + R S S E+ HR++ Q RQS + Q + H
Sbjct: 508 Q----CRQSR---SSSKERDHRRSRSPSKERQRRQSRSPNKER--DRSQSRSPSEEREHR 558
Query: 721 SQEGPCGTQDRRTHKD-EQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDE 779
P +DRR + + +RR ++ E+ H R +KQ+ R R + + E
Sbjct: 559 QSRSPSKERDRRRWRSPSKERERRQSRSSSEERDH---SRSRSPNKQSGYSRPRASSK-E 614
Query: 780 QNHQR 784
+ H R
Sbjct: 615 KAHSR 619
Score = 58.5 bits (140), Expect = 2e-08
Identities = 72/336 (21%), Positives = 135/336 (40%), Gaps = 27/336 (8%)
Query: 93 SHGGRTSQQERGQEG-AQDCKFPGNTGRQHRQRHEEERQNSH-HSQPERQDGDSHHG--Q 148
S GR SQ +G +Q+ GR H ++ SH HS+ ++ D H G
Sbjct: 324 SQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERD-HRGSSS 382
Query: 149 PERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGK 208
P ++ S G KQ RD S+ + RD ++S + +D S +S +++D S +
Sbjct: 383 PRKESGRSQSGSPNKQ-RDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441
Query: 209 ---KVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQ 265
K +S S ++ + + +R +D +S + LG S +
Sbjct: 442 SPYKARDRSRS-RSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRS 500
Query: 266 KSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQ 325
+S S +E C RQ +SS + R+ +S + RQ +S + + Q
Sbjct: 501 RSPS---------KERQC----RQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQ 547
Query: 326 GQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGS----HYSQPNRQGQSSHYGQ 381
+S + RQ +S + R+ + ++ RQ + S +S+ + S Y +
Sbjct: 548 SRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSR 607
Query: 382 PDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQ 417
P + + ++ + ++ Q+ + S SQ
Sbjct: 608 PRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQ 643
Score = 56.6 bits (135), Expect = 9e-08
Identities = 97/502 (19%), Positives = 198/502 (39%), Gaps = 55/502 (10%)
Query: 309 QTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTN-RQGQGSHY 367
+T + ++S R+G S P R+G S R R G S
Sbjct: 99 RTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRV 158
Query: 368 SQPNRQGQSSH---YGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQG 424
P Q + S YG+P T ++ ++D Q ++ G S G+
Sbjct: 159 RTPTSQQKGSRGKSYGRPRTSNRE----RSDSQPRNLSKKSYRPPGGSGI-------GRS 207
Query: 425 SHYGQTDRQGQ-SSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQ 483
S T + + G P ++ ++ + R+ +S YGQ + YS + +
Sbjct: 208 SELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKS--YGQMIIPSREKSYSPTEMSSR 265
Query: 484 SSHYGKIDRQD--QSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSH----YSQ 537
Y + + QS+ + + +S +T + +S + + + +S SQ
Sbjct: 266 VKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQ 325
Query: 538 MDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKY 597
M R QS + + G+S + +T R+G+S+++ + + +S + +S + E +
Sbjct: 326 MGRHSQSRSHSK----GKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE-----RD 376
Query: 598 FQGTEGTRKASYVEQSGRSGR----LSQQTPGQEGYQNQGQG-FQSRDSQQNGHQVWEPE 652
+G+ RK S QSG + ++P + +++ + +++RD ++ +
Sbjct: 377 HRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436
Query: 653 EDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSH----WAEEE 708
+K + + P +K RD S R +S + H +E
Sbjct: 437 CSRSRSPYKARDRSRSRSP--NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKE 494
Query: 709 QGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQR-----RDRQTHEHEQSHQRRDR-QTH 762
+ H+ R S+E C + R+ E++H+R ++RQ + ++ RDR Q+
Sbjct: 495 RDHR---RSRSPSKERQC--RQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 763 EDKQNRQRRDRQTHEDEQNHQR 784
+ R+ R ++ E++ +R
Sbjct: 550 SPSEEREHRQSRSPSKERDRRR 571
Score = 54.3 bits (129), Expect = 4e-07
Identities = 77/416 (18%), Positives = 137/416 (32%), Gaps = 39/416 (9%)
Query: 124 RHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHN 183
R + Q S S+P Q Q R +S Q R HS+ +H+
Sbjct: 265 RVKSYNQASTRSRP----------QSHSQSRSPRRSRSGSQKRT--HSRVRSHSWKRNHS 312
Query: 184 QSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQS 243
++ + + Q R SQ S K S + + + H ++ N P ++ + S
Sbjct: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRN----PSKERSHSHS 368
Query: 244 ERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQ 303
+++ + G +S ++ + +SGS Q + DR S Y DR
Sbjct: 369 RSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRS 428
Query: 304 SYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQ 363
D S Y DR S D S DR
Sbjct: 429 RSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDR--------------- 473
Query: 364 GSHYSQPNRQGQSSHYGQP--DTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQ 421
S P+++ S G P + + S +RQ + S ER + S +RQ
Sbjct: 474 -SRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQ 532
Query: 422 GQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQ 481
+ S +R S +R+ + S +R + +R+ + S S ++
Sbjct: 533 RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERD 592
Query: 482 GQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQ 537
S ++ Y +P + + ++ + ++ Q + S SQ
Sbjct: 593 HSRSR-----SPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQ 643
Score = 46.2 bits (108), Expect = 1e-04
Identities = 67/386 (17%), Positives = 133/386 (34%), Gaps = 18/386 (4%)
Query: 97 RTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDS 156
+ S + R Q +Q + ++ H R +S R + G + R
Sbjct: 271 QASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGR-- 328
Query: 157 HHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTS 216
H QS + +Q R HN S K+ S S SS K+ H+ +S
Sbjct: 329 -HSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSR------SSSKERDHRGSS 381
Query: 217 GQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSER 276
K G ++ P + + +S + + S + ++ +S S +
Sbjct: 382 SPRKESGR----SQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDC 437
Query: 277 LGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPD- 335
DR S D DR S + D S + D
Sbjct: 438 SRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDH 497
Query: 336 RQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTD 395
R+ +S + R+ + ++ +R+ + + RQ +S + + +Q +S +
Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557
Query: 396 RQDQSSHYGQTERQGQSSHYSQMDRQGQGS----HYGQTDRQGQSSHYGQPDRQGQNSHY 451
RQ +S + R+ +S + RQ + S + ++ + S Y +P + +
Sbjct: 558 RQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAH 617
Query: 452 GQTDRQGQSSHYGQTDRQGQSSHYSQ 477
++ + ++ Q+ + S SQ
Sbjct: 618 SRSRTPSKEGNHSQSRTSSKESDPSQ 643
Score = 39.3 bits (90), Expect = 0.014
Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 119 RQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDR 178
R+ + EER +S P +Q G + +P ++ H +S ++ +HSQ +
Sbjct: 581 RRQSRSSSEERDHSRSRSPNKQSG---YSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSK 637
Query: 179 DSHHNQS---ERQDKDFSFDQSERQSQDSSSGKKVSHKSTS 216
+S +QS D S ++ SQ+ + K SH ++
Sbjct: 638 ESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPST 678
Score = 37.4 bits (85), Expect = 0.054
Identities = 39/224 (17%), Positives = 87/224 (38%), Gaps = 11/224 (4%)
Query: 119 RQHRQRHEEERQNSHH-SQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQD 177
R H Q ++ H S+ ++ + ++RD +S ++R S+ ++
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 178 RDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQD 237
RD ++S ++++ +S + +D + S + Q++ +R P +
Sbjct: 543 RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQ 602
Query: 238 SHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQ 297
S Y + +++ +H K G++ QS +E Q+ +S + +
Sbjct: 603 SGYSRPRASSKEK------AHSRSRTPSKEGNH-SQSRTSSKESDPSQS-TVPRSPDWKR 654
Query: 298 TDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSS 341
+ + S +T + S S GQ+ SQ D Q ++
Sbjct: 655 SPTRTSSLSQNRTPSKTSSHSPSTFPSGGQT--LSQDDSQADAT 696
>gi|5454034 S100 calcium-binding protein, beta [Homo sapiens]
Length = 92
Score = 66.6 bits (161), Expect = 8e-11
Identities = 31/92 (33%), Positives = 54/92 (58%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
M++L +++++IDVFH+Y+ GD L K ELK+L+ E L+ + E V+ ++
Sbjct: 1 MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMET 60
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNK 92
LD D DG DF E++ V + AC+ +++
Sbjct: 61 LDNDGDGECDFQEFMAFVAMVTTACHEFFEHE 92
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 66.2 bits (160), Expect = 1e-10
Identities = 123/516 (23%), Positives = 198/516 (38%), Gaps = 89/516 (17%)
Query: 124 RHEEERQNSHHSQPERQDGDSHHGQPERQD-RDSHHGQSE---KQDRDSHHSQPERQDRD 179
+ EE+ + PE Q+ + +P+ Q+ + H Q E K + + E+ RD
Sbjct: 58 KQEEKHMTAVKGLPE-QECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRD 116
Query: 180 SHHNQSERQDK---DFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQ 236
N+ ++K D DQ E +D G K + + +GH+ L + E ++
Sbjct: 117 QQLNKQLEEEKKLLDQQLDQ-ELVKRDEQLGMK-KEQLLELPEQQEGHLKHLEQQEGQLK 174
Query: 237 --DSHYGQSERHTQQSETL----GQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQG 290
+ GQ E QQ L Q QQ+ GQ E Q+ G + Q
Sbjct: 175 HPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE-----GQLELPEQQEGQLELPEQQ 229
Query: 291 QSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQ--SSHYGQM-- 346
+ GQ + Q + Q + ++GQ H + Q + GQ+
Sbjct: 230 E----GQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKY 285
Query: 347 --DRKGQCYHYDQTNRQGQGSHYSQPNRQ-GQSSHYGQPDTQDQSSHYGQTDRQDQSSHY 403
++GQ H DQ +Q + P +Q GQ H Q + Q H Q + Q +
Sbjct: 286 LEQQEGQLKHLDQQEKQPE-----LPEQQMGQLKHLEQ--QEGQPKHLEQQEGQLEQLE- 337
Query: 404 GQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHY 463
E++GQ H Q ++GQ H + Q G P++Q + +QGQ H
Sbjct: 338 ---EQEGQLKHLEQ--QEGQLEHL-----EHQEGQLGLPEQQVLQLKQLE-KQQGQPKHL 386
Query: 464 GQTDRQGQSSHYSQPDKQGQSSHY----GKIDRQD-QSYHYGQPDGQ--------GQSSH 510
+ +GQ H Q ++GQ H G++++Q+ Q H Q GQ GQ H
Sbjct: 387 --EEEEGQLKHLVQ--QEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKH 442
Query: 511 YGQTDRQGQ----SFHYGQPDRQGQSSHYSQMDRQ--GQSSHYGQTDRQ--------GQS 556
Q +QGQ GQP Q ++ Q GQ H + + Q GQ
Sbjct: 443 LEQ--QQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQP 500
Query: 557 SHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQ 592
H Q Q H ++Q +++ Q G+++
Sbjct: 501 KHLEQ-----QEKHLEHPEQQDGQLKHLEQQEGQLK 531
Score = 60.8 bits (146), Expect = 5e-09
Identities = 111/498 (22%), Positives = 196/498 (39%), Gaps = 75/498 (15%)
Query: 232 EKPIQDSHYGQSERHTQQSETLGQA--SHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQ 289
E+ +Q H+ Q E + Q++E Q Q +QQ + + + L Q+L R
Sbjct: 84 EQELQQQHWEQHEEY-QKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD 142
Query: 290 GQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQ--SSHYGQMD 347
Q +++Q + ++G H Q ++GQ H Q + Q + GQ++
Sbjct: 143 EQLGM-----KKEQLLELPE-QQEGHLKHLEQ--QEGQLKHPEQQEGQLELPEQQEGQLE 194
Query: 348 RKGQCYHYDQTNRQGQGSHYSQPNRQGQ----SSHYGQPDTQDQSSHYGQTDRQDQSSHY 403
Q + Q +G ++GQ GQ + Q + Q +
Sbjct: 195 LPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLE 254
Query: 404 GQTERQGQSSHYSQMDRQ--------GQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTD 455
+++GQ H + Q GQ + Q ++GQ H Q ++Q +
Sbjct: 255 LSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQ--QEGQLKHLDQQEKQPELPE----Q 308
Query: 456 RQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTD 515
+ GQ H Q ++GQ H Q + Q + +++ Q H Q +GQ + +
Sbjct: 309 QMGQLKHLEQ--QEGQPKHLEQQEGQLEQLE----EQEGQLKHLEQQEGQLEHLEH---- 358
Query: 516 RQGQSFHYGQPDRQGQSSHYSQMDR-QGQSSHYGQTDRQGQSSHYGQTDRQGQSYHY--- 571
++GQ G P++ Q Q+++ QGQ H + +GQ H Q ++GQ H
Sbjct: 359 QEGQ---LGLPEQ--QVLQLKQLEKQQGQPKHL--EEEEGQLKHLVQ--QEGQLKHLVQQ 409
Query: 572 -GQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQ 630
GQ ++Q + +++ Q G++ K+ + EQ G+ L QQ GQ
Sbjct: 410 EGQLEQQERQVEHLEQQVGQL----KHLE-----------EQEGQLKHLEQQ-QGQLEVP 453
Query: 631 NQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQ 690
Q G Q ++ +Q Q+ PE+ +H + Q E P G Q EQ +
Sbjct: 454 EQQVG-QPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVG---QPKHLEQQEKH 509
Query: 691 AQTRQSHGEGLSHWAEEE 708
+ + L H ++E
Sbjct: 510 LEHPEQQDGQLKHLEQQE 527
Score = 59.3 bits (142), Expect = 1e-08
Identities = 114/484 (23%), Positives = 185/484 (38%), Gaps = 104/484 (21%)
Query: 119 RQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQ-----------------DRDSHHGQS 161
+QH ++HEE ++ + Q +Q+ Q +Q RD G
Sbjct: 89 QQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMK 148
Query: 162 EKQ------DRDSHHSQPERQDRD-SHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKS 214
++Q ++ H E+Q+ H Q E Q + + + + + G+ +
Sbjct: 149 KEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ 208
Query: 215 TSGQ----AKWQGHIFALNRCEKPIQ--DSHYGQSERHTQQSETL-------GQASHFNQ 261
GQ + +G + + E ++ GQ E QQ L GQ H
Sbjct: 209 QEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHL-- 266
Query: 262 TNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQ 321
+ + G E++GQ Q ++GQ H Q ++Q + + GQ H Q
Sbjct: 267 --EHQEGQLEVPEEQMGQLKYLEQ--QEGQLKHLDQQEKQPEL----PEQQMGQLKHLEQ 318
Query: 322 TDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQ 381
++GQ H Q + Q + +++GQ H +Q ++GQ H + Q G
Sbjct: 319 --QEGQPKHLEQQEGQLEQLE----EQEGQLKHLEQ--QEGQLEHL-----EHQEGQLGL 365
Query: 382 PDTQDQSSHYGQTDRQD-QSSHYGQTERQGQSSHYSQMDRQGQGSHY----GQTDRQ-GQ 435
P + Q Q ++Q Q H E +GQ H Q ++GQ H GQ ++Q Q
Sbjct: 366 P--EQQVLQLKQLEKQQGQPKHL--EEEEGQLKHLVQ--QEGQLKHLVQQEGQLEQQERQ 419
Query: 436 SSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQ--------GQSSHYSQPDKQ------ 481
H Q + GQ H +++GQ H Q Q GQ + Q +KQ
Sbjct: 420 VEHLEQ--QVGQLKHL--EEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQ 475
Query: 482 --GQSSHYGKIDRQDQSYHYGQPDGQ-GQSSHYGQTDRQGQSFHYGQPDRQ-GQSSHYSQ 537
GQ H K + Q + P+ Q GQ H Q ++ H P++Q GQ H Q
Sbjct: 476 QEGQVKHLEKQEAQLE-----LPEQQVGQPKHLEQQEK-----HLEHPEQQDGQLKHLEQ 525
Query: 538 MDRQ 541
+ Q
Sbjct: 526 QEGQ 529
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 65.9 bits (159), Expect = 1e-10
Identities = 85/504 (16%), Positives = 160/504 (31%), Gaps = 65/504 (12%)
Query: 331 YSQPDRQGQ----SSHYGQM--DRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDT 384
+S PDR+ + S YG + + Q + G+ + +G DT
Sbjct: 83 WSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDT 142
Query: 385 QDQSSHYGQTDRQDQSSHYGQTERQGQSS-HYSQMDRQGQGSHYGQTDRQGQSSHYGQPD 443
+D + H SH + E + SS H+ + R G H G+ D +G+ + +
Sbjct: 143 EDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDD-EGEEEEEEEEE 201
Query: 444 RQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQ-------- 495
+ ++ YG + + + + H+ P + Q D D
Sbjct: 202 EEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDD 261
Query: 496 -SYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQG 554
S Y + Q + + H+ P + +S D S+ YG +
Sbjct: 262 VSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRH 321
Query: 555 QSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSG 614
Q + + +H+ D + Q + E ++ QG + E+
Sbjct: 322 QDHRKEEVEAVSGEHHHHVPDHRHQGHR--DEEEDEDVSTERWHQGPQHVHHGLVDEEEE 379
Query: 615 RSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCH 674
Q +Q +G D Q E + + HH H + + + E
Sbjct: 380 EEEITVQFGHYVASHQPRGHKSDEEDFQD------EYKTEVPHHHHHRVPREEDEEVSAE 433
Query: 675 KGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSH----------ESQEG 724
G Q+ S Q H+ +T + + GH SH E +E
Sbjct: 434 LGH--QAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEED 491
Query: 725 PC------------------GTQDRRTHKDEQN----------HQRRDRQTHEHEQSHQR 756
P G++D+ +DE+ + D++ E E+ +R
Sbjct: 492 PGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEER 551
Query: 757 RDRQTHEDKQNRQRRDRQTHEDEQ 780
R+ + + E+E+
Sbjct: 552 REERAEVGAPLSPDHSEEEEEEEE 575
Score = 56.6 bits (135), Expect = 9e-08
Identities = 97/541 (17%), Positives = 182/541 (33%), Gaps = 68/541 (12%)
Query: 145 HHGQPERQDRDSHHGQSEKQDRDSHH--SQPERQDRDSHHNQSERQDKDFSFDQSERQSQ 202
HH R D + S + + HH S P+R+ D ++ Q +
Sbjct: 59 HHLHSPRDHPDENKDVSTE---NGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGD 115
Query: 203 DSSSGKKVSHKSTSGQAKW-QGHIFALNRCEKPIQDSHYGQSER-HTQQSETLGQ---AS 257
+ SG++V + GQA+ +GH E + H+ S R H+ Q E + +
Sbjct: 116 EGVSGEEVFAEH-GGQARGHRGH--GSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSE 172
Query: 258 HFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQT-------------DRQDQS 304
H + + + G+ + G+E + + + S+ YG D D
Sbjct: 173 HHHHILRHGHRGHDGEDDE-GEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGH 231
Query: 305 YHYGQTDR-QGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQ 363
+H+G + R QG + D D S Y + Q + ++
Sbjct: 232 HHHGPSHRHQGH-----EEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSD 286
Query: 364 GSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQ 423
G H+ P+ + +S D D S+ YG + Q + E H+ D + Q
Sbjct: 287 GHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQ 346
Query: 424 GSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQ 483
G + D + + Q Q+ H+G D + + +SH + K +
Sbjct: 347 GHRDEEEDEDVSTERWHQGP---QHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDE 403
Query: 484 SSHYGKIDRQDQSYHY---GQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR 540
+ + +H+ + + + S+ G + H + GQ +M
Sbjct: 404 EDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSH 463
Query: 541 QGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQG 600
H DR SH + D + + + + SH ++ E QG
Sbjct: 464 H-PPGHTVVKDR----SHLRKDDSEEE-----KEKEEDPGSHEEDDESSE--------QG 505
Query: 601 TEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQH 660
+GT S Q ++ + G + ++ + E EED + +
Sbjct: 506 EKGTHHGS-----------RDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREE 554
Query: 661 K 661
+
Sbjct: 555 R 555
Score = 52.4 bits (124), Expect = 2e-06
Identities = 83/530 (15%), Positives = 178/530 (33%), Gaps = 65/530 (12%)
Query: 95 GGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDR 154
G R+ + G EG + G Q R H S+ + H P +
Sbjct: 105 GHRSQDHKVGDEGVSGEEVFAEHGGQAR------GHRGHGSEDTEDSAEHRHHLPSHR-- 156
Query: 155 DSHHGQSEKQDR---DSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVS 211
SH Q E +D HH R H + + + ++ E + ++ + +
Sbjct: 157 -SHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGE-----EEEEEEEEEEEASTEYG 210
Query: 212 HKSTSGQAKWQGHIFALNRCEKPIQDS--HYGQSERHT--QQSETLGQASHFNQTNQQKS 267
H++ + +GH + ++ + D H+G S RH ++ + + + S
Sbjct: 211 HQA----HRHRGH---GSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVS 263
Query: 268 GSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQ 327
Y Q+ R H G +D+ G H+ + +
Sbjct: 264 IEYRHQAHR-----------------HQGHGIEEDEDVSDGH--------HHRDPSHRHR 298
Query: 328 SSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQ 387
S D S+ YG + Q + ++ H+ P+ + Q H + + +D
Sbjct: 299 SHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQ-GHRDEEEDEDV 357
Query: 388 SSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQ 447
S+ + + Q H+G + + + + SH + + + + +
Sbjct: 358 STE--RWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVP 415
Query: 448 NSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQ 507
+ H+ + R+ + Q S S D++ G I ++ S+H
Sbjct: 416 HHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSI--KEMSHHPPGHTVVKD 473
Query: 508 SSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQ 567
SH + D + + P + S+ +G +H+G D++ + + + +G
Sbjct: 474 RSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKG--THHGSRDQEDE-----EDEEEGH 526
Query: 568 SYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSG 617
Q + + + + + E + + + G + S E+ G
Sbjct: 527 GLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG 576
Score = 51.6 bits (122), Expect = 3e-06
Identities = 71/399 (17%), Positives = 143/399 (35%), Gaps = 69/399 (17%)
Query: 90 DNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQN----------SHHSQPER 139
D + G ++E +E ++ G+ +HR EE ++ SH Q
Sbjct: 186 DGEDDEGEEEEEEEEEEEEASTEY-GHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHE 244
Query: 140 QDGDSHHGQPERQDRDS-----------HHGQSEKQDRD----SHHSQPERQDRDSHHNQ 184
+D D + D D H G ++D D HH P + R H +
Sbjct: 245 EDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRS--HEE 302
Query: 185 SERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQ-------AKWQGH-------IFALNR 230
+ D D S + Q+ +K ++ SG+ + QGH + R
Sbjct: 303 DDNDDDDVSTEYG-HQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTER 361
Query: 231 CEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQG 290
+ Q H+G + ++ E Q H+ ++Q + + +E + +
Sbjct: 362 WHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPR-------GHKSDEEDFQDEYKTEV 414
Query: 291 QSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDR-- 348
H+ + R++ + + H + + RQ SH + GQ +M
Sbjct: 415 PHHHHHRVPREEDE------EVSAELGHQAPSHRQ---SHQDEETGHGQRGSIKEMSHHP 465
Query: 349 KGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQ---SSHYGQTDRQDQSSHYGQ 405
G D+++ + S + + SH ++ +Q +H+G D++D+ +
Sbjct: 466 PGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEED---E 522
Query: 406 TERQGQSSHYSQMDRQGQGSHYGQTD--RQGQSSHYGQP 442
E G S + + + + + + D R+ + + G P
Sbjct: 523 EEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAP 561
Score = 41.2 bits (95), Expect = 0.004
Identities = 44/190 (23%), Positives = 59/190 (31%), Gaps = 35/190 (18%)
Query: 625 GQEGYQNQGQGFQSRDSQQNGHQVW--EPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSC 682
G EG + + F Q GH+ E EDS H+H L R H+ D
Sbjct: 114 GDEGVSGE-EVFAEHGGQARGHRGHGSEDTEDSAEHRHHL----PSHRSHSHQDEDEDEV 168
Query: 683 SSEQ--------GHRQAQTRQSHGEGLSHWAEEEQ------GHQTWDRHSHESQEGPCGT 728
S + GHR GE EEE+ GHQ H S+E +
Sbjct: 169 VSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVS 228
Query: 729 QDRRTHKDEQNHQRRDRQTHEH--------------EQSHQRRDRQTHEDKQNRQRRDRQ 774
H HQ + + E HQ Q H +++ D
Sbjct: 229 DGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGH 288
Query: 775 THEDEQNHQR 784
H D + R
Sbjct: 289 HHRDPSHRHR 298
Score = 40.4 bits (93), Expect = 0.006
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 24/135 (17%)
Query: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNT---GRQH-------RQRHEEERQNSHH-- 134
H+ + HG R S +E PG+T R H ++ +EE SH
Sbjct: 445 HQDEETGHGQRGSIKEMSHHP------PGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEED 498
Query: 135 -SQPERQDGDSHHG---QPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQD- 189
E+ + +HHG Q + +D + HG S Q+ + + E ++ + + ER +
Sbjct: 499 DESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEV 558
Query: 190 -KDFSFDQSERQSQD 203
S D SE + ++
Sbjct: 559 GAPLSPDHSEEEEEE 573
>gi|5454032 S100 calcium binding protein A1 [Homo sapiens]
Length = 94
Score = 63.5 bits (153), Expect = 7e-10
Identities = 31/84 (36%), Positives = 51/84 (60%)
Query: 2 AQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNLL 61
++L ++ ++I+VFH ++ GD L K+ELK+LL E L D + V+ ++ L
Sbjct: 3 SELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKEL 62
Query: 62 DQDRDGHIDFHEYLLLVFQLVQAC 85
D++ DG +DF EY++LV L AC
Sbjct: 63 DENGDGEVDFQEYVVLVAALTVAC 86
>gi|39777614 SS18-like protein 1 [Homo sapiens]
Length = 396
Score = 62.8 bits (151), Expect = 1e-09
Identities = 72/267 (26%), Positives = 108/267 (40%), Gaps = 44/267 (16%)
Query: 410 GQSSHYSQMDRQGQ-GSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDR 468
G +S M QG G++ +T+ QS+ +Q SHY QG S HY
Sbjct: 156 GPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY----- 208
Query: 469 QGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHY-GQTDRQGQSFHYGQPD 527
QGQSS GQ S + Q Y +P QG S Y GQ + G+ + + Q
Sbjct: 209 QGQSSIAMM----GQGSQGSSMMGQRPMAPY-RPSQQGSSQQYLGQEEYYGEQYSHSQGA 263
Query: 528 RQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQ 587
+ Y D G + Y Q+ QS Y ++ + ++Y +G +S Y Q Q
Sbjct: 264 AEPMGQQYYP-DGHGDYA-YQQSSYTEQS--YDRSFEESTQHYY-----EGGNSQYSQQQ 314
Query: 588 TGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGF---QSRDSQQN 644
G QG ++ +Y +Q Q P Q+ Y Q QG+ Q SQ
Sbjct: 315 AGYQQG---------AAQQQTYSQQ---------QYPSQQSYPGQQQGYGSAQGAPSQYP 356
Query: 645 GHQVWEPEEDSQHHQHKLLAQIQQERP 671
G+Q + ++ + + QQ+RP
Sbjct: 357 GYQQGQGQQYGSYRAPQTAPSAQQQRP 383
Score = 53.9 bits (128), Expect = 6e-07
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 361 QGQGS---HYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQ 417
QGQG+ + S+ N QS+ Q +SHY Q S HY QGQSS
Sbjct: 165 QGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY-----QGQSS---- 213
Query: 418 MDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHY-GQTDRQGQSSHYGQTDRQGQSSHYS 476
+ GQGS Q + Y +P +QG + Y GQ + G+ + Q + Y
Sbjct: 214 IAMMGQGSQGSSMMGQRPMAPY-RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQY- 271
Query: 477 QPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYS 536
PD G + Y + +QSY + G + Q Y Q Q Q+ YS
Sbjct: 272 YPDGHGDYA-YQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQT--YS 328
Query: 537 QMDRQGQSSHYGQTDRQGQSSHYGQTD---------RQGQSYHYGQTDRQGQSSHYIQSQ 587
Q Q S+ GQ +QG YG +QGQ YG + R Q++ Q Q
Sbjct: 329 QQQYPSQQSYPGQ--QQG----YGSAQGAPSQYPGYQQGQGQQYG-SYRAPQTAPSAQQQ 381
Query: 588 T--GEIQGQNKYFQ 599
G QGQ +Q
Sbjct: 382 RPYGYEQGQYGNYQ 395
Score = 47.8 bits (112), Expect = 4e-05
Identities = 60/212 (28%), Positives = 82/212 (38%), Gaps = 26/212 (12%)
Query: 257 SHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQS--SHYGQTDRQDQSYHYGQTDRQG 314
SH++ Q S Y GQS G + GQ + Y + + + GQ + G
Sbjct: 196 SHYSSA-QGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYG 254
Query: 315 QSSHYSQTDRQGQSSHYSQPDRQG----QSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQP 370
+ +SQ + Y PD G Q S Y + Q +G S YSQ
Sbjct: 255 EQYSHSQGAAEPMGQQY-YPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQ- 312
Query: 371 NRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTE----RQGQSSHYSQMDRQGQGSH 426
Q + Y Q Q Q+ Y Q Q S+ GQ + QG S Y +QGQG
Sbjct: 313 ----QQAGYQQGAAQQQT--YSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGY-QQGQGQQ 365
Query: 427 YGQTDRQGQSSHYGQPDR-----QGQNSHYGQ 453
YG + R Q++ Q R QGQ +Y Q
Sbjct: 366 YG-SYRAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
Score = 45.1 bits (105), Expect = 3e-04
Identities = 59/228 (25%), Positives = 87/228 (38%), Gaps = 27/228 (11%)
Query: 504 GQGQSSHY-GQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQT 562
GQG +Y +T+ QS +Q +SHYS QG S HY QGQSS
Sbjct: 166 GQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSA--QGGSQHY-----QGQSS----I 214
Query: 563 DRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQ 622
GQ Q + Y SQ QG ++ + G E Y G + + QQ
Sbjct: 215 AMMGQGSQGSSMMGQRPMAPYRPSQ----QGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQ 270
Query: 623 TPGQEGYQNQGQGFQSRDSQQNGHQVWEP--EEDSQHHQHKLLAQIQQERPLCHKGRDWQ 680
Y G G + Q ++ EE +QH+ +Q Q++ +G Q
Sbjct: 271 ------YYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQ 324
Query: 681 SCSSEQGH--RQAQTRQSHGEGLSHWAEEE-QGHQTWDRHSHESQEGP 725
S+Q + +Q+ Q G G + A + G+Q + S P
Sbjct: 325 QTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAP 372
Score = 31.2 bits (69), Expect = 3.9
Identities = 35/168 (20%), Positives = 58/168 (34%), Gaps = 13/168 (7%)
Query: 136 QPERQDGDSHH-GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSF 194
+P +Q + GQ E H Q + + D + Q D SF
Sbjct: 236 RPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSF 295
Query: 195 DQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLG 254
++S + + + + ++ Q Q ++ + P Q S+ GQ + +
Sbjct: 296 EESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQ--QYPSQQSYPGQQQGYGSAQGAPS 353
Query: 255 QASHFNQTNQQKSGSYCGQSERLGQELGCGQTDR-----QGQSSHYGQ 297
Q + Q Q+ GSY R Q Q R QGQ +Y Q
Sbjct: 354 QYPGYQQGQGQQYGSY-----RAPQTAPSAQQQRPYGYEQGQYGNYQQ 396
>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
Length = 1714
Score = 61.6 bits (148), Expect = 3e-09
Identities = 64/290 (22%), Positives = 89/290 (30%), Gaps = 7/290 (2%)
Query: 272 GQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHY 331
GQ R G++ GQ G+ G + +S G +G H G+
Sbjct: 1110 GQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIP 1169
Query: 332 SQPDRQGQSSHYGQMDRKGQC-YHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSH 390
QGQ G KG+ Y + + G +P G G+P + H
Sbjct: 1170 GYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGH 1229
Query: 391 YGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSH 450
G + G T +QG QG G +G+ G + G
Sbjct: 1230 VGVPGLR------GATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283
Query: 451 YGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSH 510
G +G ++G G P KQG G R + G P +G S
Sbjct: 1284 QGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGL 1343
Query: 511 YGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYG 560
G QG G P + G QG G +GQ YG
Sbjct: 1344 PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYG 1393
Score = 57.0 bits (136), Expect = 7e-08
Identities = 78/354 (22%), Positives = 111/354 (31%), Gaps = 24/354 (6%)
Query: 277 LGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDR 336
LG+ G +G GQ R + GQ G+ + G+S
Sbjct: 1091 LGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGT 1150
Query: 337 QGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDR 396
+G H G M G+ QGQ P +G+ + G + S+ G
Sbjct: 1151 RGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPG-----EDSTVLGPPGP 1205
Query: 397 QDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDR 456
+ + G +G+ +G H G +G + G P G G
Sbjct: 1206 RGEPGPVGDQGERGEPG------AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGE 1259
Query: 457 QGQSSHYGQTDRQGQSSHYSQPDKQGQ------SSHYGKIDRQDQSYHYGQPDGQGQSSH 510
+G + G+ G S P QG ++G G P QG
Sbjct: 1260 RGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGI 1319
Query: 511 YGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYH 570
G R G + G P +G S QG G + G G QG
Sbjct: 1320 RGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP 1379
Query: 571 YGQTDRQGQSSHY-IQSQTGEIQGQNKYFQGTEGTR-KASYVEQSGRSGRLSQQ 622
G +GQ Y +Q TG QG F G +G A V SG G + +
Sbjct: 1380 CGDPGLKGQPGEYGVQGLTG-FQG----FPGPKGPEGDAGIVGISGPKGPIGHR 1428
Score = 53.5 bits (127), Expect = 7e-07
Identities = 55/256 (21%), Positives = 78/256 (30%), Gaps = 9/256 (3%)
Query: 326 GQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQ 385
G +P +G H G +G T +QG QG G +
Sbjct: 1213 GDQGERGEPGAEGYKGHVGVPGLRGA------TGQQGPPGEPGDQGEQGLKGERGSEGNK 1266
Query: 386 DQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQ 445
+ G + + G +G ++ G G +QG G P R
Sbjct: 1267 GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRT 1326
Query: 446 GQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQ 505
G G +G S G QG P + G G Q G P +
Sbjct: 1327 GLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLK 1386
Query: 506 GQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQT---DRQGQSSHYGQT 562
GQ YG G G +G + +G H G T R+G G+T
Sbjct: 1387 GQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRT 1446
Query: 563 DRQGQSYHYGQTDRQG 578
+G+ G+T QG
Sbjct: 1447 GPRGEKGFRGETGPQG 1462
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/277 (20%), Positives = 82/277 (29%), Gaps = 9/277 (3%)
Query: 272 GQSERLGQELGCGQTDRQGQSSHYG------QTDRQDQSYHYGQTDRQGQSSHYSQTDRQ 325
G+ +G + G+ +G H G T +Q G QG +
Sbjct: 1207 GEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNK 1266
Query: 326 GQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQ 385
G+ + G G + KG ++ G P +QG G P
Sbjct: 1267 GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRT 1326
Query: 386 DQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQ 445
+ G + S G QG + G G QG G P +
Sbjct: 1327 GLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLK 1386
Query: 446 GQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGK---IDRQDQSYHYGQP 502
GQ YG G G +G + +G H G + R+ G+
Sbjct: 1387 GQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRT 1446
Query: 503 DGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMD 539
+G+ G+T QG G P G QMD
Sbjct: 1447 GPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMD 1483
Score = 47.0 bits (110), Expect = 7e-05
Identities = 83/416 (19%), Positives = 124/416 (29%), Gaps = 42/416 (10%)
Query: 254 GQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTD-- 311
G F + + G + G E G+ QG G+T G T
Sbjct: 810 GPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869
Query: 312 -RQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQP 370
+G+ QG+ P G G + G H G Q
Sbjct: 870 GEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPG---HVGARGPPGSQGPKGQR 926
Query: 371 NRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQT 430
+G G+ Q G ++ G+T G+ + QG G
Sbjct: 927 GSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDR 986
Query: 431 DR---------QGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQ 481
QG G+ +G G++ QG+ G G +P +
Sbjct: 987 GLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLR 1046
Query: 482 GQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQ 541
G+ G+ Q + G P G+G G+ G G R GQ+
Sbjct: 1047 GEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIV 1106
Query: 542 GQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGT 601
G G+ ++G G T G G+ + G +G
Sbjct: 1107 GIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGP-------------------KGA 1147
Query: 602 EGTRKA-SYVEQSGRSGRLSQQTPGQEGYQ-NQGQGFQSRDSQQNGHQVWEPEEDS 655
GTR A ++ G G PG GY+ +QGQ S G + + P EDS
Sbjct: 1148 RGTRGAVGHLGLMGPDGE-----PGIPGYRGHQGQPGPSGLPGPKGEKGY-PGEDS 1197
Score = 45.1 bits (105), Expect = 3e-04
Identities = 60/303 (19%), Positives = 84/303 (27%), Gaps = 18/303 (5%)
Query: 308 GQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHY 367
G+ +G H +G + P G G +G + + G
Sbjct: 1219 GEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKP 1278
Query: 368 SQPNRQGQ------SSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQ 421
P QG ++G G +Q G R G + +
Sbjct: 1279 GIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVK 1338
Query: 422 GQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQ 481
G G QG G P + G G QG G +GQ Y
Sbjct: 1339 GSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLT 1398
Query: 482 GQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQ 541
G G + + G +G H G T G+ G R G +
Sbjct: 1399 GFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGP---------R 1449
Query: 542 GQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGT 601
G+ G+T QG G G Q D I+S T Q + +Q T
Sbjct: 1450 GEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTAL---QMESYQNT 1506
Query: 602 EGT 604
E T
Sbjct: 1507 EVT 1509
Score = 44.3 bits (103), Expect = 4e-04
Identities = 63/303 (20%), Positives = 87/303 (28%), Gaps = 31/303 (10%)
Query: 334 PDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQ 393
P G S + G KG QG +P G G P G
Sbjct: 698 PGPMGLSGNKGLPGIKGD------KGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP 751
Query: 394 TDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQ 453
+ + G + G + GQ G +G + G P G G+
Sbjct: 752 SGQTGDPGLQGPSGPPGPEGFPGDIGIPGQN---GPEGPKGLLGNRGPPGPPGLKGTQGE 808
Query: 454 TDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQ 513
G G + GQ + +P +G G++ Q G+ G G
Sbjct: 809 EGPIGAFGELGPRGKPGQKGYAGEPGPEGLK---GEVGDQGNIGKIGETGPVGLPGEVGM 865
Query: 514 TDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQ 573
T G+ G P G M G G G H G G GQ
Sbjct: 866 TGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQ 925
Query: 574 TDRQGQ----SSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGY 629
+G IQ GE Q K +G G G++G PG+ G+
Sbjct: 926 RGSRGPDGLLGEQGIQGAKGEKGDQGK--RGPHGL--------IGKTG-----NPGERGF 970
Query: 630 QNQ 632
Q +
Sbjct: 971 QGK 973
Score = 43.5 bits (101), Expect = 8e-04
Identities = 77/383 (20%), Positives = 112/383 (29%), Gaps = 42/383 (10%)
Query: 270 YCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSS 329
Y G +G G + G S G Q S G G Q +G
Sbjct: 730 YPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKG 789
Query: 330 HYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSS 389
G G +G + + +G + GQ + G+P +
Sbjct: 790 LLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRG---------KPGQKGYAGEPGPEGLKG 840
Query: 390 HYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNS 449
G + G G+ + +G+ G QG+ G P G
Sbjct: 841 EVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPG 900
Query: 450 HYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSS 509
G G H G G Q +G G+ Q G +G
Sbjct: 901 PIGPL---GLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHG 957
Query: 510 HYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSY 569
G+T G+ G+P QG S DR G G QG G+ +G
Sbjct: 958 LIGKTGNPGERGFQGKPGLQGLPG--STGDR-GLPGEPGLRGLQGDVGPPGEMGMEGPPG 1014
Query: 570 HYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSG-RLSQQTPGQEG 628
G++ QG+ +G GT A V +G G R PG+EG
Sbjct: 1015 TEGESGLQGEPG----------------AKGDVGT--AGSVGGTGEPGLRGEPGAPGEEG 1056
Query: 629 YQNQ--------GQGFQSRDSQQ 643
Q + G+G D ++
Sbjct: 1057 LQGKDGLKGVPGGRGLPGEDGEK 1079
Score = 42.0 bits (97), Expect = 0.002
Identities = 57/313 (18%), Positives = 91/313 (29%), Gaps = 24/313 (7%)
Query: 272 GQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHY 331
G+ +G G + GQ + G+ G +G+ + G++
Sbjct: 807 GEEGPIGAFGELGPRGKPGQKGYAGEP---------GPEGLKGEVGDQGNIGKIGETGPV 857
Query: 332 SQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQ------SSHYGQPDTQ 385
P G + G+ +G +G + P G H G
Sbjct: 858 GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP 917
Query: 386 DQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQ 445
GQ + G+ QG ++G G+T G+ G+P Q
Sbjct: 918 GSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQ 977
Query: 446 GQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQ 505
G G T +G G QG + +G G+ Q G+P +
Sbjct: 978 GLP---GSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQ------GEPGAK 1028
Query: 506 GQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQ 565
G G G+ G+P G+ + +G G G+ G
Sbjct: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGII 1088
Query: 566 GQSYHYGQTDRQG 578
G GQT G
Sbjct: 1089 GPLGRSGQTGLPG 1101
Score = 36.2 bits (82), Expect = 0.12
Identities = 65/319 (20%), Positives = 83/319 (26%), Gaps = 13/319 (4%)
Query: 308 GQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHY 367
G+ QG S QG P G G G RQG
Sbjct: 549 GEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPE 608
Query: 368 SQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHY 427
P +G G P Q G+ G RQG + G
Sbjct: 609 GNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDF------GDRGPA 662
Query: 428 GQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHY 487
G G G P G G G + G G S + P +G
Sbjct: 663 GLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPA---GIPGPMGLSGNKGLPGIKGDKGEQ 719
Query: 488 GKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHY 547
G + + G G G + G S G P QG S G
Sbjct: 720 GTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779
Query: 548 GQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYF--QGTEGTR 605
GQ +G G G G +G + + GQ Y G EG +
Sbjct: 780 GQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLK 839
Query: 606 KASYVEQSGRSGRLSQQTP 624
V G G++ + P
Sbjct: 840 --GEVGDQGNIGKIGETGP 856
Score = 30.0 bits (66), Expect = 8.6
Identities = 36/154 (23%), Positives = 44/154 (28%), Gaps = 3/154 (1%)
Query: 428 GQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHY---GQTDRQGQSSHYSQPDKQGQS 484
G+ +G +G P G G G S G+ QG S P QG
Sbjct: 510 GKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDK 569
Query: 485 SHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
G G P G G RQG + G P +G GQ
Sbjct: 570 GLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQL 629
Query: 545 SHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQG 578
G+ G G RQG +G G
Sbjct: 630 GPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAG 663
Score = 30.0 bits (66), Expect = 8.6
Identities = 57/280 (20%), Positives = 75/280 (26%), Gaps = 21/280 (7%)
Query: 361 QGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDR 420
QG P G G P G RQ + G +G
Sbjct: 566 QGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGE 625
Query: 421 QGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDK 480
GQ G+ G G RQG +G G G G P
Sbjct: 626 AGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGF---PGL 682
Query: 481 QGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR 540
+G G I G +G G QG + G+P G
Sbjct: 683 RGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGP 742
Query: 541 QGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQN----- 595
G G + + G G + G G GQ+ + G + +
Sbjct: 743 PGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGP--EGPKGLLGNRGPPGPP 800
Query: 596 --KYFQGTEGTRKASYVEQSGRSGRLSQQ-TPGQEGYQNQ 632
K QG EG G G L + PGQ+GY +
Sbjct: 801 GLKGTQGEEG--------PIGAFGELGPRGKPGQKGYAGE 832
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 58.9 bits (141), Expect = 2e-08
Identities = 90/563 (15%), Positives = 206/563 (36%), Gaps = 71/563 (12%)
Query: 45 LQRPNDPETVETILNLLDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERG 104
L R DP+ E + + Q+R+G E S G + E+
Sbjct: 1752 LNRDKDPKLGEAEGDAMAQEREGKTHNSE------------------TSAGSELGEAEQE 1793
Query: 105 QEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDG--------DSHHGQPERQDRDS 156
EG + G G H + E P + DG QPE + ++
Sbjct: 1794 GEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEA 1853
Query: 157 HHGQSEKQDRDSHHSQPERQDRDSHHNQSERQ--DKDFSFDQSERQSQDSSSGKKVSHKS 214
+ + Q+ + +QPE +D ++ + E Q +D ++E + Q S G +
Sbjct: 1854 PEAEGDAQEAEG-EAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAE 1912
Query: 215 TSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQS 274
Q + + + AL G+ E ++ +E A + Q+ G +S
Sbjct: 1913 KEAQPETES-VEALET---------EGEDEPESEGAE----AQEAEEAAQEAEGQTQPES 1958
Query: 275 ERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQG---QSSHY 331
E + + + + + + + + Q + + Q +S + +G ++
Sbjct: 1959 EVIESQEAEEEAQPESEDVEALEVEVETQE---AEGEAQPESEDVEAPEAEGEMQEAEEE 2015
Query: 332 SQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQD----- 386
+QP+ G + + Q + +G +QP G + + + Q+
Sbjct: 2016 AQPESDGVEAQPKSEGEEAQEVEGETQKTEGD----AQPESDGVEAPEAEEEAQEAEGEV 2071
Query: 387 -QSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQ 445
++ + +D + + E Q +S + +G+ + + ++ QP+ +
Sbjct: 2072 QEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGE-AQKAEGIEAPETEGEAQPESE 2130
Query: 446 GQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQ 505
G + + + Q +S D +G+ +QP+ +G + + + Q + P+ +
Sbjct: 2131 GIEAPEAEGEAQPESEGVEAQDAEGE----AQPESEGIEAQEAEEEAQPELEGVEAPEAE 2186
Query: 506 GQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQ 565
G++ + ++ QP+ +G + ++ + Q + + +G++ + + Q
Sbjct: 2187 GEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQ 2246
Query: 566 GQ-------SYHYGQTDRQGQSS 581
G+ S GQ++ +SS
Sbjct: 2247 GEKKGSPQVSLGDGQSEEASESS 2269
>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
Length = 2526
Score = 58.2 bits (139), Expect = 3e-08
Identities = 63/270 (23%), Positives = 83/270 (30%), Gaps = 10/270 (3%)
Query: 308 GQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHY 367
G G T QG P GQ G KG G+ +
Sbjct: 1419 GHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCH 1478
Query: 368 SQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHY 427
P +G+ G P +Q G + + G GQ+++ ++G
Sbjct: 1479 GFPGIKGEK---GDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIK--GQKGSKGEQ 1533
Query: 428 GQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQS---SHYGQTDRQGQSSHYSQPDKQGQS 484
G+ R GQ G P +G GQ +G S + G T G QG
Sbjct: 1534 GRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNP 1593
Query: 485 SHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
G+ Q Q G P G G+ G+ G P G Q RQG S
Sbjct: 1594 GRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDS 1653
Query: 545 S--HYGQTDRQGQSSHYGQTDRQGQSYHYG 572
YGQ R+G G GQ G
Sbjct: 1654 GIPGYGQMGRKGVKGPRGFPGDAGQKGDIG 1683
Score = 53.9 bits (128), Expect = 6e-07
Identities = 41/162 (25%), Positives = 59/162 (36%), Gaps = 8/162 (4%)
Query: 421 QGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDK 480
QG G + G+ G P GQN++ ++G G+ R GQ P
Sbjct: 1493 QGSPGSRGAPGQYGEKGFPGDPGNPGQNNNI--KGQKGSKGEQGRQGRSGQKGVQGSPSS 1550
Query: 481 QGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR 540
+G G+ + S G+P G + G QG G P R+G+ Q
Sbjct: 1551 RGSRGREGQRGLRGVS---GEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGP 1607
Query: 541 QGQ---SSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQ 579
QG G T R G G+ G GQT ++G+
Sbjct: 1608 QGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGR 1649
Score = 48.9 bits (115), Expect = 2e-05
Identities = 56/223 (25%), Positives = 77/223 (34%), Gaps = 27/223 (12%)
Query: 409 QGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDR 468
QG G G T QG G P GQ G + +G G
Sbjct: 1412 QGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGL 1471
Query: 469 QGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDR 528
G+ + P +G+ G G P +G YG+ G + GQ +
Sbjct: 1472 DGEEGCHGFPGIKGEKGDPGS---------QGSPGSRGAPGQYGEKGFPGDPGNPGQNNN 1522
Query: 529 -QGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQ 587
+GQ + RQG+S GQ QG S G R+GQ G + G
Sbjct: 1523 IKGQKGSKGEQGRQGRS---GQKGVQGSPSSRGSRGREGQRGLRGVSGEPGN-----PGP 1574
Query: 588 TGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQ 630
TG + + QG +G++ GR G Q GQ+G Q
Sbjct: 1575 TGTLGAEG--LQGPQGSQ-----GNPGRKGEKGSQ--GQKGPQ 1608
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/178 (24%), Positives = 58/178 (32%), Gaps = 9/178 (5%)
Query: 272 GQSERL-GQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSH 330
GQ+ + GQ+ G+ RQG+S G G+ ++G + G +
Sbjct: 1518 GQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGT 1577
Query: 331 YSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSH 390
QG G RKG + QGQ P G G+P +
Sbjct: 1578 LGAEGLQGPQGSQGNPGRKG------EKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGE 1631
Query: 391 YGQTDRQDQSSHYGQTERQGQSS--HYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQG 446
G GQ RQG S Y QM R+G G GQ G P G
Sbjct: 1632 PGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPG 1689
>gi|56117846 synovial sarcoma translocation, chromosome 18 isoform 1
[Homo sapiens]
Length = 418
Score = 58.2 bits (139), Expect = 3e-08
Identities = 75/261 (28%), Positives = 96/261 (36%), Gaps = 42/261 (16%)
Query: 358 TNRQGQ--GSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHY 415
T QGQ G++ +PN Q + Q S Y Q HY QGQ
Sbjct: 180 TMSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMP--QGGGQHY-----QGQQPPM 232
Query: 416 SQMDRQGQGSHY-GQTD-------RQGQSSHY-GQPDRQG-QNSHYGQTDRQGQSSHY-- 463
M + QG+H GQ +QG Y GQ D G Q SH GQ +G + Y
Sbjct: 233 GMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYP 292
Query: 464 -GQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFH 522
G D Q Y + QG Y +D S HY + G +S YGQ Q +
Sbjct: 293 DGHNDYGYQQPSYPE---QGYDRPY-----EDSSQHYYE----GGNSQYGQQ----QDAY 336
Query: 523 YGQPDRQG----QSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQG 578
G P +QG Q + Q GQ YG + + QGQ Y + + G
Sbjct: 337 QGPPPQQGYPPQQQQYPGQQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPG 396
Query: 579 QSSHYIQSQTGEIQGQNKYFQ 599
Q G QGQ +Q
Sbjct: 397 PPQPPQQRPYGYDQGQYGNYQ 417
Score = 55.8 bits (133), Expect = 1e-07
Identities = 64/251 (25%), Positives = 88/251 (35%), Gaps = 24/251 (9%)
Query: 405 QTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYG 464
Q + GQ + M QG G + + G +H Q
Sbjct: 120 QNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNH-SVPSSQSMPVQNQ 178
Query: 465 QTDRQGQ--SSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDG-----QGQSSHYGQTDRQ 517
T QGQ ++ +P+ Q + + +Q S Y P G QGQ G +
Sbjct: 179 MTMSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQV 238
Query: 518 GQSFHY-GQ-------PDRQGQSSHYS-QMDRQG-QSSHYGQTDRQGQSSHYGQTDRQGQ 567
Q H GQ P +QG YS Q D G Q SH GQ +G + Y
Sbjct: 239 NQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGHNDY 298
Query: 568 SYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGR--LSQQTPG 625
Y QG Y S +G N + G ++ +Y + G QQ PG
Sbjct: 299 GYQQPSYPEQGYDRPYEDSSQHYYEGGNSQY----GQQQDAYQGPPPQQGYPPQQQQYPG 354
Query: 626 QEGYQNQGQGF 636
Q+GY Q QG+
Sbjct: 355 QQGYPGQQQGY 365
Score = 53.1 bits (126), Expect = 1e-06
Identities = 60/244 (24%), Positives = 82/244 (33%), Gaps = 24/244 (9%)
Query: 314 GQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQ 373
G + S QG H P +Q G +GQ + QG+H Q
Sbjct: 191 GPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMG---Q 247
Query: 374 GQSSHYGQPDTQDQSSHYGQTDRQ-DQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432
Q Y P + GQ D DQ SH GQ +G + Y G
Sbjct: 248 RQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGHNDYGYQQPSYPE 307
Query: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQG----QSSHYG 488
QG Y +P +Y +G +S YGQ Q ++ P +QG Q + G
Sbjct: 308 QG----YDRPYEDSSQHYY-----EGGNSQYGQQ----QDAYQGPPPQQGYPPQQQQYPG 354
Query: 489 KIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMD---RQGQSS 545
+ Q YG G + QGQ + +P + G Q QGQ
Sbjct: 355 QQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRPYGYDQGQYG 414
Query: 546 HYGQ 549
+Y Q
Sbjct: 415 NYQQ 418
Score = 52.4 bits (124), Expect = 2e-06
Identities = 71/271 (26%), Positives = 92/271 (33%), Gaps = 37/271 (13%)
Query: 388 SSH--YGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQ 445
SSH G + SS + Q S M G + QG H P +Q
Sbjct: 155 SSHGSMGGYNHSVPSSQSMPVQNQMTMSQGQPMGNYGPRPNMSMQPNQGPMMHQQPPSQQ 214
Query: 446 GQNSHYGQTDRQGQSSHYGQTDRQGQSSH---------YSQPDK------QGQSSHYGKI 490
G QGQ G + Q +H Y P + GQ +YG
Sbjct: 215 YNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYG-- 272
Query: 491 DRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHY---SQMDRQGQSSHY 547
DQ H GQ +G + Y + QG Y SQ +G +S Y
Sbjct: 273 ---DQYSHGGQGPPEGMNQQYYPDGHNDYGYQQPSYPEQGYDRPYEDSSQHYYEGGNSQY 329
Query: 548 GQTDRQGQSSHYGQTDRQG----QSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEG 603
GQ Q ++ G +QG Q + GQ GQ Y SQ G Y QG +G
Sbjct: 330 GQQ----QDAYQGPPPQQGYPPQQQQYPGQQGYPGQQQGYGPSQGGPGPQYPNYPQG-QG 384
Query: 604 TRKASYVEQSGRSGRLSQQTPGQEGYQNQGQ 634
+ Y + QQ P GY +QGQ
Sbjct: 385 QQYGGYRPTQPGPPQPPQQRP--YGY-DQGQ 412
Score = 32.3 bits (72), Expect = 1.7
Identities = 56/202 (27%), Positives = 76/202 (37%), Gaps = 41/202 (20%)
Query: 222 QGHIFALNRCEKPIQDSHYGQSERHTQQSETLG-QASHFNQTNQQKSGSYCGQSERLGQE 280
QG+ R P + G ++++ Q + G Q SH Q G E + Q+
Sbjct: 240 QGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQ----------GPPEGMNQQ 289
Query: 281 L-GCGQTDRQGQSSHYGQT--DR--QDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPD 335
G D Q Y + DR +D S HY +G +S Y Q Q ++ P
Sbjct: 290 YYPDGHNDYGYQQPSYPEQGYDRPYEDSSQHY----YEGGNSQYGQQ----QDAYQGPPP 341
Query: 336 RQG----QSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPN-RQGQSSHYG-------QPD 383
+QG Q + GQ GQ Y ++ G G Y PN QGQ YG P
Sbjct: 342 QQGYPPQQQQYPGQQGYPGQQQGYG-PSQGGPGPQY--PNYPQGQGQQYGGYRPTQPGPP 398
Query: 384 TQDQSSHYGQTDRQDQSSHYGQ 405
Q YG Q Q +Y Q
Sbjct: 399 QPPQQRPYGYD--QGQYGNYQQ 418
>gi|5174663 S100 calcium binding protein P [Homo sapiens]
Length = 95
Score = 57.8 bits (138), Expect = 4e-08
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
M +L ++ +IDVF +Y+ G L K ELK L+ E LQ D + V+ +L
Sbjct: 1 MTELETAMGMIIDVFSRYSGSEGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKD 60
Query: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKS 93
LD + D +DF E+++ V + AC HK K+
Sbjct: 61 LDANGDAQVDFSEFIVFVAAITSAC-HKYFEKA 92
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 57.8 bits (138), Expect = 4e-08
Identities = 73/409 (17%), Positives = 161/409 (39%), Gaps = 41/409 (10%)
Query: 123 QRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHH 182
QR +EE + + Q + DS + + ++ + ++ + S + E R H
Sbjct: 161 QREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETH 220
Query: 183 NQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQ 242
Q+K S ++S ++S + + ++ + + GQ + Q E+ +D+
Sbjct: 221 AAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQ------EESEEGEEDATSEV 274
Query: 243 SERHTQQSETLG-----QASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQ 297
+R T+ G ++S ++ G +SE + R S+HY
Sbjct: 275 DKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRA 334
Query: 298 TDRQDQSYHYGQTDRQGQSSHYSQTDRQGQ------SSHYSQPDRQGQSS-------HYG 344
++ + + YG+ + +G + D + + S Y P Q + S +Y
Sbjct: 335 SEEEPE---YGE-EIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYP 390
Query: 345 QMDRKGQCYHYDQTNRQ------GQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQD 398
++ + Y + + + G+G H+ R G+ Y DT+++ G+ +
Sbjct: 391 SLELDKMAHGYGEESEEERGLEPGKGRHHR--GRGGEPRAYFMSDTREEKRFLGEGHHRV 448
Query: 399 QSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQG 458
Q + + R Q + + ++DR +YG+ G+ G +N + +
Sbjct: 449 QENQMDKARRHPQGA-WKELDR--NYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQ 505
Query: 459 QSSHYGQTDRQ--GQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQ 505
SSH+ R+ G+ + Q +SSH+ + D + ++ G+ + +
Sbjct: 506 YSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENE 554
Score = 52.4 bits (124), Expect = 2e-06
Identities = 81/384 (21%), Positives = 138/384 (35%), Gaps = 75/384 (19%)
Query: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDG--DSHHGQP 149
K+H S QE G+E TG Q + H +E + SQ E ++G D+
Sbjct: 228 KTHSREKSSQESGEE----------TGSQ--ENHPQESKGQPRSQEESEEGEEDATSEVD 275
Query: 150 ERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKK 209
+R+ R HH + DR S +++ H Q E ++ + S +S G+K
Sbjct: 276 KRRTRPRHHHGRSRPDRSSQGGSLPSEEKG--HPQEESEESNVSM---------ASLGEK 324
Query: 210 VSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLG-----QASHFNQTNQ 264
H ST HY SE + E + QA + +
Sbjct: 325 RDHHST-----------------------HYRASEEEPEYGEEIKGYPGVQAPEDLEWER 361
Query: 265 QKS-GSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQ------GQSS 317
+ GS ++ R E + D++ +Y + ++ YG+ + G+
Sbjct: 362 YRGRGSEEYRAPRPQSEESWDEEDKR----NYPSLELDKMAHGYGEESEEERGLEPGKGR 417
Query: 318 HYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSS 377
H+ R G+ Y D + + G+ + Q D+ R QG+
Sbjct: 418 HH--RGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYG 475
Query: 378 HYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQ--SSHYSQMDRQGQGSHYG--QTDRQ 433
G P Q Q D QD + + Q + SSH++ R+ G + Q
Sbjct: 476 EEGAPGKWQQ-----QGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQ 530
Query: 434 GQSSHYGQPDRQGQNSHYGQTDRQ 457
+SSH+ + D N G+ + +
Sbjct: 531 WKSSHFERRDNMNDNFLEGEEENE 554
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/302 (20%), Positives = 111/302 (36%), Gaps = 39/302 (12%)
Query: 495 QSYHYGQPDGQGQSSHYGQT--DRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDR 552
+S G+ G+ G T D + + G + +S Q S +T
Sbjct: 97 ESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRH 156
Query: 553 QGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQG------------QNKYFQG 600
+S + + +G++Y G+ +++ + GE Q + +
Sbjct: 157 SEKSQREDEEEEEGENYQKGERGEDSSEEKHLE-EPGETQNAFLNERKQASAIKKEELVA 215
Query: 601 TEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQH 660
T A + ++ S S Q G+E + +S+ ++ + E EED+
Sbjct: 216 RSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVD 275
Query: 661 KLLAQIQQERPLCHKGRDWQSCSS--------EQGHRQAQTRQSHGEGLSHWAEEEQGHQ 712
K ++ RP H GR SS E+GH Q ++ +S+ ++ E+ H
Sbjct: 276 K-----RRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESN-VSMASLGEKRDHHS 329
Query: 713 TWDRHSHESQE------GPCGTQDRRTHKDEQNHQRRDRQTHEHEQSH-QRRDRQTHEDK 765
T R S E E G G Q +D + + R R + E+ Q + EDK
Sbjct: 330 THYRASEEEPEYGEEIKGYPGVQ---APEDLEWERYRGRGSEEYRAPRPQSEESWDEEDK 386
Query: 766 QN 767
+N
Sbjct: 387 RN 388
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 57.0 bits (136), Expect = 7e-08
Identities = 83/433 (19%), Positives = 160/433 (36%), Gaps = 49/433 (11%)
Query: 366 HYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQT-ERQGQSSHYSQMDRQGQG 424
H + R+ ++ P GQ Q+ GQ E++GQ R+ +G
Sbjct: 33 HIKELKRKLETDKIPLPQEGQVREQEGQVREQE-----GQVREQEGQVREQEGQVREQEG 87
Query: 425 S---HYGQT-DRQGQ-SSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPD 479
GQ +++GQ GQ Q + + Q + + Q + +
Sbjct: 88 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147
Query: 480 KQGQ-SSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYS-Q 537
++GQ G++ Q+ + +GQ + +++GQ +++GQ Q
Sbjct: 148 QEGQVREQEGQVREQEGQVR--EQEGQVREQEGQVREQEGQV-----REQEGQMGEQEGQ 200
Query: 538 MDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKY 597
M Q + + Q Q G+ + Q + Q ++ G+ +Q Q ++Q Q +
Sbjct: 201 MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK----QEEQMGEQEEQVQKQEEQVQKQEEQ 256
Query: 598 FQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQH 657
+ E + + + ++ +Q E Q + G Q ++ Q+ E EE +
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTE--QEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 658 HQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQ-GHQTWDR 716
+ ++ Q +Q ++ Q Q + W +EEQ G Q
Sbjct: 315 QEEQMREQEEQ-------------MGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
Query: 717 HSHE----SQEGPCGTQDRRTHKDEQNHQRRDRQTHEH-----EQSHQRRDRQTHEDKQN 767
E QE Q+ + K E+ ++++ Q E EQ Q R+++ +Q
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Query: 768 RQRRDRQTHEDEQ 780
Q R ++ H EQ
Sbjct: 422 EQMRKQEEHMGEQ 434
Score = 56.6 bits (135), Expect = 9e-08
Identities = 62/303 (20%), Positives = 121/303 (39%), Gaps = 12/303 (3%)
Query: 493 QDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDR 552
++Q + +GQ + +++GQ R+ Q + + Q + ++
Sbjct: 76 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-QEGQVREQEGQVREQEGQVREQ 134
Query: 553 QGQ-SSHYGQT-DRQGQSYHY-GQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASY 609
+GQ GQ +++GQ GQ Q + Q E +GQ + +G ++
Sbjct: 135 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQM 194
Query: 610 VEQSGRSGRLSQQTPGQEGY---QNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQI 666
EQ G+ G +Q QE Q + G Q ++ Q+ E EE Q + ++ Q
Sbjct: 195 GEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE 254
Query: 667 QQERPLCHKGRDWQSCSSEQGHR----QAQTRQSHGEGLSHWAEEEQGHQTWDRHSH-ES 721
+Q R + R+ + EQ + + QT Q G EQ Q ++
Sbjct: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 722 QEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQN 781
QE Q+ + K E+ + Q E ++ +++ Q E ++ Q+++ Q + E+
Sbjct: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
Query: 782 HQR 784
++
Sbjct: 375 MRK 377
Score = 44.3 bits (103), Expect = 4e-04
Identities = 44/252 (17%), Positives = 94/252 (37%), Gaps = 20/252 (7%)
Query: 96 GRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRD 155
G+ +QE GQ G Q+ G G Q Q E+E Q + + + Q E+
Sbjct: 185 GQVREQE-GQMGEQE----GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQ 239
Query: 156 SHHGQSEKQDRDSHHSQPERQDRDSHHNQSE-RQDKDFSFDQSERQSQDSSSGKKVSHKS 214
Q +++ Q +Q+ + + R+ ++ Q E+ Q+ +G++
Sbjct: 240 EEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
Query: 215 TSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQS 274
+ + E+ +++ Q E+ +Q E +G+ Q +QK + +
Sbjct: 300 EQEE--------QMREQEEQMRE----QEEQMREQEEQMGKQE--EQMWEQKEQMWEQKE 345
Query: 275 ERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQP 334
+ QE G+ + Q Q +++Q + R+ + Q ++ G+
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE 405
Query: 335 DRQGQSSHYGQM 346
++ QM
Sbjct: 406 QKEQMREQEEQM 417
Score = 41.6 bits (96), Expect = 0.003
Identities = 51/318 (16%), Positives = 115/318 (36%), Gaps = 28/318 (8%)
Query: 96 GRTSQQE---RGQEGAQDCKFPGNTGRQHRQRHEEERQ-NSHHSQPERQDGDSHHGQPER 151
G+ +QE R QEG Q + G Q Q E+E Q Q Q+G + +
Sbjct: 136 GQVREQEGQVREQEG-QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQM 194
Query: 152 QDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVS 211
+++ G+ E+Q + +++++ + R+ ++ +Q E+ + +K
Sbjct: 195 GEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE 254
Query: 212 HKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYC 271
+ + + E+ +++ E+ Q + Q QT +Q+
Sbjct: 255 EQ--------------MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 272 GQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHY 331
+ + QE + + Q + +++Q + + + + + Q ++ G+
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 332 SQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQ--DQSS 389
Q + QM ++ +Q +Q + + Q G+ Q +Q
Sbjct: 361 MQKQEEQVRKQEEQMRKQ-----EEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415
Query: 390 HYGQTDRQ--DQSSHYGQ 405
G+ Q Q H G+
Sbjct: 416 QMGEQKEQMRKQEEHMGE 433
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,452,315
Number of Sequences: 37866
Number of extensions: 1845232
Number of successful extensions: 20990
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 290
Number of HSP's successfully gapped in prelim test: 410
Number of HSP's that attempted gapping in prelim test: 7099
Number of HSP's gapped (non-prelim): 5439
length of query: 784
length of database: 18,247,518
effective HSP length: 110
effective length of query: 674
effective length of database: 14,082,258
effective search space: 9491441892
effective search space used: 9491441892
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.