Search of human proteins with 170650730

Search of human proteins with 170650730

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170650730 pituitary specific transcription factor 1 isoform
beta [Homo sapiens]
         (317 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170650730 pituitary specific transcription factor 1 isoform b...   640   0.0  
gi|4505955 pituitary specific transcription factor 1 isoform alp...   573   e-164
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...   181   8e-46
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                      181   8e-46
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s...   181   8e-46
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s...   179   4e-45
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                     164   1e-40
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap...   160   1e-39
gi|148664218 POU transcription factor [Homo sapiens]                  159   3e-39
gi|223890225 POU class 6 homeobox 1 [Homo sapiens]                    141   7e-34
gi|42560248 POU domain, class 5, transcription factor 1 isoform ...   141   7e-34
gi|116235491 POU domain, class 5, transcription factor 1 isoform...   140   1e-33
gi|4505965 POU class 4 homeobox 3 [Homo sapiens]                      139   4e-33
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...   136   3e-32
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]     135   5e-32
gi|227430410 POU class 5 homeobox 1B [Homo sapiens]                   132   5e-31
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...   119   4e-27
gi|23463326 POU domain class 5, transcription factor 2 [Homo sap...   105   7e-23
gi|11641283 LIM homeobox protein 5 [Homo sapiens]                      50   3e-06
gi|30410785 LIM homeobox protein 1 [Homo sapiens]                      49   6e-06
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    48   1e-05
gi|50083287 LIM homeobox 8 [Homo sapiens]                              47   2e-05
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]           45   6e-05
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]           45   6e-05
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]            45   8e-05
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]             45   8e-05
gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]                45   1e-04
gi|15375314 LIM homeobox protein 4 [Homo sapiens]                      45   1e-04
gi|147901462 brain specific homeobox [Homo sapiens]                    44   1e-04
gi|27777663 goosecoid [Homo sapiens]                                   44   1e-04

>gi|170650730 pituitary specific transcription factor 1 isoform beta
           [Homo sapiens]
          Length = 317

 Score =  640 bits (1652), Expect = 0.0
 Identities = 317/317 (100%), Positives = 317/317 (100%)

Query: 1   MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTVPSILSLIQTPKC 60
           MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTVPSILSLIQTPKC
Sbjct: 1   MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTVPSILSLIQTPKC 60

Query: 61  LCTHFSVTTLGNTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIH 120
           LCTHFSVTTLGNTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIH
Sbjct: 61  LCTHFSVTTLGNTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIH 120

Query: 121 QPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVG 180
           QPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVG
Sbjct: 121 QPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVG 180

Query: 181 EALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERK 240
           EALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERK
Sbjct: 181 EALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERK 240

Query: 241 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT 300
           RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT
Sbjct: 241 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT 300

Query: 301 SLNQSLFSISKEHLECR 317
           SLNQSLFSISKEHLECR
Sbjct: 301 SLNQSLFSISKEHLECR 317


>gi|4505955 pituitary specific transcription factor 1 isoform alpha
           [Homo sapiens]
          Length = 291

 Score =  573 bits (1478), Expect = e-164
 Identities = 291/317 (91%), Positives = 291/317 (91%), Gaps = 26/317 (8%)

Query: 1   MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTVPSILSLIQTPKC 60
           MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMST             
Sbjct: 1   MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMST------------- 47

Query: 61  LCTHFSVTTLGNTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIH 120
                        ATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIH
Sbjct: 48  -------------ATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIH 94

Query: 121 QPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVG 180
           QPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVG
Sbjct: 95  QPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVG 154

Query: 181 EALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERK 240
           EALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERK
Sbjct: 155 EALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERK 214

Query: 241 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT 300
           RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT
Sbjct: 215 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKT 274

Query: 301 SLNQSLFSISKEHLECR 317
           SLNQSLFSISKEHLECR
Sbjct: 275 SLNQSLFSISKEHLECR 291


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
           sapiens]
          Length = 443

 Score =  181 bits (459), Expect = 8e-46
 Identities = 91/152 (59%), Positives = 115/152 (75%), Gaps = 2/152 (1%)

Query: 149 DMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKN 208
           D D+P   +LE+FA +FK RRIKLG+TQ +VG AL  ++G+ FSQTTICRFE LQLSFKN
Sbjct: 261 DEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKN 320

Query: 209 ACKLKAILSKWLEEAEQVGALYN--EKVGANERKRKRRTTISIAAKDALERHFGEQNKPS 266
            CKLK +L+KWLEEA+         +K+ A  RKRK+RT+I ++ K ALE HF +  KPS
Sbjct: 321 MCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPS 380

Query: 267 SQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298
           +QEI  +A+ L LEKEVVRVWFCNRRQ+EKR+
Sbjct: 381 AQEITSLADSLQLEKEVVRVWFCNRRQKEKRM 412


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score =  181 bits (459), Expect = 8e-46
 Identities = 92/152 (60%), Positives = 118/152 (77%), Gaps = 2/152 (1%)

Query: 149 DMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKN 208
           D D+P   +LE+FA +FK RRIKLG+TQ +VG AL  ++G+ FSQTTICRFE LQLSFKN
Sbjct: 313 DEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKN 372

Query: 209 ACKLKAILSKWLEEAE-QVGALYN-EKVGANERKRKRRTTISIAAKDALERHFGEQNKPS 266
            CKLK +L+KWLEEA+   G+  + +K+ A  RKRK+RT+I ++ K ALE HF +  KPS
Sbjct: 373 MCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPS 432

Query: 267 SQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298
           +QEI  +A+ L LEKEVVRVWFCNRRQ+EKR+
Sbjct: 433 AQEITNLADSLQLEKEVVRVWFCNRRQKEKRM 464


>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
           sapiens]
          Length = 451

 Score =  181 bits (459), Expect = 8e-46
 Identities = 100/193 (51%), Positives = 125/193 (64%), Gaps = 2/193 (1%)

Query: 108 PDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKV 167
           P H  +HG    H         AA            V E  D D+P   +LE+FA +FK 
Sbjct: 205 PPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQ 264

Query: 168 RRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAE-QV 226
           RRIKLG+TQ +VG AL  ++G+ FSQTTICRFE LQLSFKN CKLK +L+KWLEE +   
Sbjct: 265 RRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSS 324

Query: 227 GALYN-EKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVR 285
           G+  N +K+ A  RKRK+RT+I +  K ALE HF +  KPS+ EI  +A+ L LEKEVVR
Sbjct: 325 GSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVR 384

Query: 286 VWFCNRRQREKRV 298
           VWFCNRRQ+EKR+
Sbjct: 385 VWFCNRRQKEKRM 397


>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
           sapiens]
          Length = 361

 Score =  179 bits (453), Expect = 4e-45
 Identities = 95/179 (53%), Positives = 126/179 (70%), Gaps = 8/179 (4%)

Query: 122 PLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGE 181
           P+L E P   +        S   ++  D ++P   ELE+FA +FK RRIKLG+TQ +VG 
Sbjct: 164 PVLREPPDHGELG------SHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGL 217

Query: 182 ALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAE-QVGALYN-EKVGANER 239
           AL  ++G+ FSQTTICRFE LQLSFKN CKLK +L+KWLEEA+   G+  + +K+ A  R
Sbjct: 218 ALGTLYGNVFSQTTICRFEGLQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGR 277

Query: 240 KRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298
           KRK+RT+I ++ K  LE HF +  KP++QEI  +A+ L LEKEVVRVWFCNRRQ+EKR+
Sbjct: 278 KRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRM 336


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score =  164 bits (415), Expect = 1e-40
 Identities = 85/164 (51%), Positives = 115/164 (70%), Gaps = 14/164 (8%)

Query: 144 VEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQ 203
           +EEP D++     ELE+FA  FK RRIKLG+TQ +VG A+  ++G++FSQTTI RFE L 
Sbjct: 279 LEEPSDLE-----ELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALN 333

Query: 204 LSFKNACKLKAILSKWLEEAEQV---------GALYNEKVGANERKRKRRTTISIAAKDA 254
           LSFKN CKLK +L KWL +AE +          AL +  +    R+RK+RT+I    + A
Sbjct: 334 LSFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVA 393

Query: 255 LERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298
           LE+ F E  KP+S+EI  +A++LN+EKEV+RVWFCNRRQ+EKR+
Sbjct: 394 LEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRI 437


>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
           sapiens]
          Length = 463

 Score =  160 bits (405), Expect = 1e-39
 Identities = 94/211 (44%), Positives = 129/211 (61%), Gaps = 25/211 (11%)

Query: 101 TPCLYKFPDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEEPIDMDSP-EIRELE 159
           TP L++ P  T           LL   P A    Q      K +E P   + P ++ ELE
Sbjct: 141 TPNLFQLPQQTQG--------ALLTSQPRAGLPTQP----PKCLEPPSHPEEPSDLEELE 188

Query: 160 KFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKW 219
           +FA  FK RRIKLG+TQ +VG A+  ++G++FSQTTI RFE L LSFKN CKLK +L KW
Sbjct: 189 QFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKW 248

Query: 220 LEEAEQVGA---------LYNEKVGAN---ERKRKRRTTISIAAKDALERHFGEQNKPSS 267
           L +AE +           L +  +G +    R+RK+RT+I    + ALE+ F    KP+S
Sbjct: 249 LNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTS 308

Query: 268 QEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298
           +EI+ +AE+L++EKEV+RVWFCNRRQ+EKR+
Sbjct: 309 EEILLIAEQLHMEKEVIRVWFCNRRQKEKRI 339


>gi|148664218 POU transcription factor [Homo sapiens]
          Length = 436

 Score =  159 bits (402), Expect = 3e-39
 Identities = 85/162 (52%), Positives = 110/162 (67%), Gaps = 13/162 (8%)

Query: 145 EEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQL 204
           +EP D++     ELEKFA  FK RRIKLG+TQ +VG A+  ++G++FSQTTI RFE L L
Sbjct: 183 DEPSDLE-----ELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNL 237

Query: 205 SFKNACKLKAILSKWLEEAE--------QVGALYNEKVGANERKRKRRTTISIAAKDALE 256
           SFKN CKLK +L KWL +AE           + Y        RKRK+RT+I    +  LE
Sbjct: 238 SFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLE 297

Query: 257 RHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298
           + F +  KPSS+EI  +AE+L++EKEVVRVWFCNRRQ+EKR+
Sbjct: 298 KRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339


>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
          Length = 301

 Score =  141 bits (356), Expect = 7e-34
 Identities = 79/165 (47%), Positives = 105/165 (63%), Gaps = 9/165 (5%)

Query: 141 SKLVEEP----IDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTI 196
           S+LV +P    +D D   + E+ +FA  FK+RR+ LG TQT VG+AL A  G  +SQ+ I
Sbjct: 126 SQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAI 185

Query: 197 CRFENLQLSFKNACKLKAILSKWLEEAE---QVGA--LYNEKVGANERKRKRRTTISIAA 251
           CRFE L ++ K+A KLK +L KWL EAE   Q G   L     G   +KRKRRT+ +  A
Sbjct: 186 CRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQA 245

Query: 252 KDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREK 296
            +AL  +F +   P+ QEI  +A+ELN ++EVVRVWFCNRRQ  K
Sbjct: 246 IEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290


>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
           [Homo sapiens]
          Length = 360

 Score =  141 bits (356), Expect = 7e-34
 Identities = 81/170 (47%), Positives = 106/170 (62%), Gaps = 6/170 (3%)

Query: 140 KSKLVEEPIDMDSPEI--RELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTIC 197
           K KL + P +    +   +ELE+FA   K +RI LGYTQ +VG  L  + G  FSQTTIC
Sbjct: 126 KEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTIC 185

Query: 198 RFENLQLSFKNACKLKAILSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDA 254
           RFE LQLSFKN CKL+ +L KW+EEA   E +  +   +     RKRK RT+I    +  
Sbjct: 186 RFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRVRGN 244

Query: 255 LERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 304
           LE  F +  KP+ Q+I  +A++L LEK+VVRVWFCNRRQ+ KR  +   Q
Sbjct: 245 LENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 294


>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
           [Homo sapiens]
          Length = 265

 Score =  140 bits (354), Expect = 1e-33
 Identities = 80/165 (48%), Positives = 104/165 (63%), Gaps = 8/165 (4%)

Query: 147 PIDMDSPEIR----ELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENL 202
           P  + S +I+    ELE+FA   K +RI LGYTQ +VG  L  + G  FSQTTICRFE L
Sbjct: 36  PFKIQSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEAL 95

Query: 203 QLSFKNACKLKAILSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDALERHF 259
           QLSFKN CKL+ +L KW+EEA   E +  +   +     RKRK RT+I    +  LE  F
Sbjct: 96  QLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRK-RTSIENRVRGNLENLF 154

Query: 260 GEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 304
            +  KP+ Q+I  +A++L LEK+VVRVWFCNRRQ+ KR  +   Q
Sbjct: 155 LQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 199


>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
          Length = 338

 Score =  139 bits (349), Expect = 4e-33
 Identities = 84/156 (53%), Positives = 105/156 (67%), Gaps = 15/156 (9%)

Query: 156 RELEKFANEFKVRRIKLGYTQTNVGEALAAVH----GSEFSQTTICRFENLQLSFKNACK 211
           RELE FA  FK RRIKLG TQ +VG ALA +     GS  SQ+TICRFE+L LS  N   
Sbjct: 185 RELEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGS-LSQSTICRFESLTLSHNNMIA 243

Query: 212 LKAILSKWLEEAEQVGALYNEK------VGANERKRKRRTTISIAAKDALERHFGEQNKP 265
           LK +L  WLEEAE   A Y EK         +ERKRKR T+I+   K +LE +F  Q +P
Sbjct: 244 LKPVLQAWLEEAE---AAYREKNSKPELFNGSERKRKR-TSIAAPEKRSLEAYFAIQPRP 299

Query: 266 SSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTS 301
           SS++I  +AE+L+L+K VVRVWFCN+RQ++KR+K S
Sbjct: 300 SSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYS 335


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score =  136 bits (342), Expect = 3e-32
 Identities = 80/155 (51%), Positives = 103/155 (66%), Gaps = 13/155 (8%)

Query: 156 RELEKFANEFKVRRIKLGYTQTNVGEALAAVH----GSEFSQTTICRFENLQLSFKNACK 211
           RELE FA  FK RRIKLG TQ +VG ALA +     GS  SQ+TICRFE+L LS  N   
Sbjct: 266 RELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGS-LSQSTICRFESLTLSHNNMIA 324

Query: 212 LKAILSKWLEEAEQVGALYNEKVGANE-----RKRKRRTTISIAAKDALERHFGEQNKPS 266
           LK IL  WLEEAE       EK+   E      K+++RT+I+   K +LE +F  Q +PS
Sbjct: 325 LKPILQAWLEEAE---GAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPS 381

Query: 267 SQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTS 301
           S++I  +AE+L+L+K VVRVWFCN+RQ++KR+K S
Sbjct: 382 SEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFS 416


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score =  135 bits (340), Expect = 5e-32
 Identities = 81/162 (50%), Positives = 110/162 (67%), Gaps = 14/162 (8%)

Query: 149 DMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVH----GSEFSQTTICRFENLQL 204
           D+D+ + R+LE FA  FK RRIKLG TQ +VG ALA +     GS  SQ+TICRFE+L L
Sbjct: 250 DVDA-DPRDLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGS-LSQSTICRFESLTL 307

Query: 205 SFKNACKLKAILSKWLEEAEQVGALYNEKVGANE-----RKRKRRTTISIAAKDALERHF 259
           S  N   LK IL  WLEEAE+    + EK+   E      K+++RT+I+   K +LE +F
Sbjct: 308 SHNNMIALKPILQAWLEEAEKS---HREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYF 364

Query: 260 GEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTS 301
             Q +PSS++I  +AE+L+L+K VVRVWFCN+RQ++KR+K S
Sbjct: 365 AIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYS 406


>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
          Length = 359

 Score =  132 bits (331), Expect = 5e-31
 Identities = 76/152 (50%), Positives = 97/152 (63%), Gaps = 5/152 (3%)

Query: 156 RELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAI 215
           +ELE+FA   K +RI LGYTQ +VG  L  + G  FSQ TICRFE LQLSFKN CKL+ +
Sbjct: 144 KELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPL 203

Query: 216 LSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMR 272
           L KW+EEA   E +  +   +     RKRK RT+I    +  LE  F +  KP+ Q I  
Sbjct: 204 LQKWVEEADNNENLQEICKAETLMQARKRK-RTSIENRVRGNLENLFLQCPKPTLQ-ISH 261

Query: 273 MAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 304
           +A++L LEK+VVRVWFCNRRQ+ KR  +   Q
Sbjct: 262 IAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 293


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score =  119 bits (298), Expect = 4e-27
 Identities = 71/197 (36%), Positives = 103/197 (52%), Gaps = 41/197 (20%)

Query: 149 DMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICR---------- 198
           ++D   + E+ +FA  FK+RR+ LG TQT VG+AL+A  G  +SQ+ ICR          
Sbjct: 475 EVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFL 534

Query: 199 --------------------------FENLQLSFKNACKLKAILSKWLEEAE--QVGALY 230
                                     FE L ++ K+A K+K +L +W+ EAE      + 
Sbjct: 535 PQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQ 594

Query: 231 N--EKVGAN-ERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVW 287
           N  E +G+   +KRKRRT+ +  A + L  HF +   PS QE+  +AE+LN ++EVVRVW
Sbjct: 595 NLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVW 654

Query: 288 FCNRRQREKRVKTSLNQ 304
           FCN+RQ  K     L Q
Sbjct: 655 FCNKRQALKNTIKRLKQ 671


>gi|23463326 POU domain class 5, transcription factor 2 [Homo
           sapiens]
          Length = 328

 Score =  105 bits (261), Expect = 7e-23
 Identities = 59/145 (40%), Positives = 88/145 (60%), Gaps = 2/145 (1%)

Query: 155 IRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKA 214
           ++EL++ A E + +R+ LGY+Q +VG A+ A+ G   SQTTICRFE  QLS  N  KL+ 
Sbjct: 123 LKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRP 182

Query: 215 ILSKWLE--EAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMR 272
           +L KWL+  EAE +  L   ++   +  + RR +      ++LE+ F    KP+ Q+I  
Sbjct: 183 LLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISH 242

Query: 273 MAEELNLEKEVVRVWFCNRRQREKR 297
           +A  L L+K+VVRVWF NR +   R
Sbjct: 243 IAGCLQLQKDVVRVWFYNRSKMGSR 267


>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
          Length = 402

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 24/69 (34%), Positives = 39/69 (56%)

Query: 231 NEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCN 290
           NE+  +  ++R  RTTI     + L+  F    KP+     ++A+E  L   V++VWF N
Sbjct: 171 NEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQN 230

Query: 291 RRQREKRVK 299
           RR +E+R+K
Sbjct: 231 RRSKERRMK 239


>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
          Length = 406

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 24/76 (31%), Positives = 41/76 (53%)

Query: 224 EQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEV 283
           ++ G+  N+      ++R  RTTI     + L+  F    KP+     ++A+E  L   V
Sbjct: 164 KEAGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRV 223

Query: 284 VRVWFCNRRQREKRVK 299
           ++VWF NRR +E+R+K
Sbjct: 224 IQVWFQNRRSKERRMK 239


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 26/60 (43%), Positives = 33/60 (55%)

Query: 238 ERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKR 297
           ERKR+RRT  +      LE  F E   P      R+A  LNL ++ V+VWF NRR + KR
Sbjct: 137 ERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKR 196


>gi|50083287 LIM homeobox 8 [Homo sapiens]
          Length = 356

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 13/124 (10%)

Query: 176 QTNVGEALAAVHGSEFSQTTI-CRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKV 234
           Q + GE  A V      +    C  +NL+   +N   +              GAL  E+ 
Sbjct: 170 QLSTGEEFALVEEKVLCRVHYDCMLDNLKREVENGNGISV-----------EGALLTEQD 218

Query: 235 GANERKRKR-RTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQ 293
             + +  KR RT+ +      ++  F + N P +Q + ++AE   L + V++VWF N R 
Sbjct: 219 VNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRA 278

Query: 294 REKR 297
           R K+
Sbjct: 279 RHKK 282


>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
          Length = 377

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 19/71 (26%), Positives = 39/71 (54%)

Query: 227 GALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRV 286
           GA+ +E+    +  ++ RT+ +      ++  F + N P +Q + ++A+   L + V++V
Sbjct: 235 GAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQV 294

Query: 287 WFCNRRQREKR 297
           WF N R R K+
Sbjct: 295 WFQNCRARHKK 305


>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
          Length = 392

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 19/71 (26%), Positives = 39/71 (54%)

Query: 227 GALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRV 286
           GA+ +E+    +  ++ RT+ +      ++  F + N P +Q + ++A+   L + V++V
Sbjct: 235 GAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQV 294

Query: 287 WFCNRRQREKR 297
           WF N R R K+
Sbjct: 295 WFQNCRARHKK 305


>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
          Length = 397

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 22/64 (34%), Positives = 36/64 (56%)

Query: 236 ANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQRE 295
           A    ++ RTTI+    + L+  +    KP+     +++ E  L+  VV+VWF NRR +E
Sbjct: 153 AEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKE 212

Query: 296 KRVK 299
           KR+K
Sbjct: 213 KRLK 216


>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
          Length = 402

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 22/64 (34%), Positives = 36/64 (56%)

Query: 236 ANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQRE 295
           A    ++ RTTI+    + L+  +    KP+     +++ E  L+  VV+VWF NRR +E
Sbjct: 158 AEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKE 217

Query: 296 KRVK 299
           KR+K
Sbjct: 218 KRLK 221


>gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]
          Length = 226

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 24/76 (31%), Positives = 38/76 (50%)

Query: 235 GANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQR 294
           G    +R+ RTT S    + LE  FG    P       +A +  L +  ++VWF NRR +
Sbjct: 64  GRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAK 123

Query: 295 EKRVKTSLNQSLFSIS 310
           +++ + SL Q L  +S
Sbjct: 124 QRKQERSLLQPLAHLS 139


>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
          Length = 390

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/59 (35%), Positives = 35/59 (59%)

Query: 241 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVK 299
           ++ RTTI+    + L+  +    KP+     +++ E  L+  VV+VWF NRR +EKR+K
Sbjct: 158 KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLK 216


>gi|147901462 brain specific homeobox [Homo sapiens]
          Length = 233

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 24/66 (36%), Positives = 36/66 (54%)

Query: 232 EKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNR 291
           E  G + R+RK RT  S +    LE+ F  Q   S+ E + +A  L+L +  V+ WF NR
Sbjct: 102 ELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNR 161

Query: 292 RQREKR 297
           R + K+
Sbjct: 162 RMKHKK 167


>gi|27777663 goosecoid [Homo sapiens]
          Length = 257

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 24/66 (36%), Positives = 37/66 (56%)

Query: 239 RKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298
           RKR+ RT  +    +ALE  F E   P      ++A +++L +E V VWF NRR + +R 
Sbjct: 159 RKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQ 218

Query: 299 KTSLNQ 304
           K S ++
Sbjct: 219 KRSSSE 224


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.130    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,763,289
Number of Sequences: 37866
Number of extensions: 521777
Number of successful extensions: 2018
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 226
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 1713
Number of HSP's gapped (non-prelim): 324
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.