Guide to the Human Genome
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Search of human proteins with 169213067

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169213067 PREDICTED: hypothetical protein [Homo sapiens]
         (303 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169213067 PREDICTED: hypothetical protein [Homo sapiens]           613   e-176
gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]           285   3e-77
gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]           285   3e-77
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     54   1e-07
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        53   4e-07
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          52   8e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    51   1e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    51   1e-06
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       51   1e-06
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             51   1e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      51   1e-06
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               50   2e-06
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      50   3e-06
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                49   7e-06
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    47   2e-05
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    47   2e-05
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    47   2e-05
gi|50511941 EMI domain containing 1 [Homo sapiens]                     47   2e-05
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       47   2e-05
gi|188536004 zinc finger protein 469 [Homo sapiens]                    46   4e-05
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    46   4e-05
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    46   4e-05
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    46   4e-05
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s...    46   5e-05
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]            46   5e-05
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    46   5e-05
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]            45   6e-05
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]            45   6e-05
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               45   6e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    45   8e-05

>gi|169213067 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 303

 Score =  613 bits (1582), Expect = e-176
 Identities = 303/303 (100%), Positives = 303/303 (100%)

Query: 1   MTAKPRSPAPGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQ 60
           MTAKPRSPAPGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQ
Sbjct: 1   MTAKPRSPAPGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQ 60

Query: 61  SQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLR 120
           SQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLR
Sbjct: 61  SQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLR 120

Query: 121 PSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGA 180
           PSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGA
Sbjct: 121 PSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGA 180

Query: 181 SGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240
           SGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG
Sbjct: 181 SGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240

Query: 241 ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESSRLLPSPRSS 300
           ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESSRLLPSPRSS
Sbjct: 241 ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESSRLLPSPRSS 300

Query: 301 ACL 303
           ACL
Sbjct: 301 ACL 303


>gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score =  285 bits (729), Expect = 3e-77
 Identities = 180/318 (56%), Positives = 197/318 (61%), Gaps = 45/318 (14%)

Query: 18  TGEKRPAQTLQRTPRKHA-----ASRGQAQAAAAALTPSLI---PRAAIRQSQAPDLLLA 69
           +G  R    LQRTP  +A     A  G+A    AA   S +   PR A+           
Sbjct: 4   SGGPRRLAGLQRTPAAYANEAALAISGRADEEGAAGAGSKLWRRPRGAV----------- 52

Query: 70  SRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGR--------AAGSPTRVQRRPRPLRP 121
           S G  G  + L    +P     P    G P+++ R        A  SP  + RR      
Sbjct: 53  SAGAPG--SPLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGR 110

Query: 122 SRAAPRLRGEEPSLLR-----PQLSRRPRALRRSTRVPA----AGKGG-------DRRAP 165
           + +A RLR    +L       P  ++ P ALR  +  PA    A  GG        R   
Sbjct: 111 AGSAGRLRCSAAALSAAQRGGPARAQVPPALRTFSPGPASPPRASPGGRPGSEARGRSGA 170

Query: 166 VFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRW 225
                VPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRW
Sbjct: 171 ECARRVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRW 230

Query: 226 PPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP 285
           PPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP
Sbjct: 231 PPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP 290

Query: 286 SILESSRLLPSPRSSACL 303
           SILESSRLLPSPRSSACL
Sbjct: 291 SILESSRLLPSPRSSACL 308


>gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score =  285 bits (729), Expect = 3e-77
 Identities = 180/318 (56%), Positives = 197/318 (61%), Gaps = 45/318 (14%)

Query: 18  TGEKRPAQTLQRTPRKHA-----ASRGQAQAAAAALTPSLI---PRAAIRQSQAPDLLLA 69
           +G  R    LQRTP  +A     A  G+A    AA   S +   PR A+           
Sbjct: 4   SGGPRRLAGLQRTPAAYANEAALAISGRADEEGAAGAGSKLWRRPRGAV----------- 52

Query: 70  SRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGR--------AAGSPTRVQRRPRPLRP 121
           S G  G  + L    +P     P    G P+++ R        A  SP  + RR      
Sbjct: 53  SAGAPG--SPLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGR 110

Query: 122 SRAAPRLRGEEPSLLR-----PQLSRRPRALRRSTRVPA----AGKGG-------DRRAP 165
           + +A RLR    +L       P  ++ P ALR  +  PA    A  GG        R   
Sbjct: 111 AGSAGRLRCSAAALSAAQRGGPARAQVPPALRTFSPGPASPPRASPGGRPGSEARGRSGA 170

Query: 166 VFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRW 225
                VPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRW
Sbjct: 171 ECARRVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRW 230

Query: 226 PPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP 285
           PPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP
Sbjct: 231 PPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP 290

Query: 286 SILESSRLLPSPRSSACL 303
           SILESSRLLPSPRSSACL
Sbjct: 291 SILESSRLLPSPRSSACL 308


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 62/208 (29%), Positives = 77/208 (37%), Gaps = 22/208 (10%)

Query: 70  SRGITGCVNALGHRGSP--EAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPR 127
           SRG+ G     G  G P      GP   RGP   AGR  G P  +  R  P  P    P 
Sbjct: 404 SRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRP-GEPGLMGPRGLPGSPGNIGPA 462

Query: 128 LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSER 187
             G+E  +  P +  RP        +  AG  G+     FP       GP G +G   + 
Sbjct: 463 --GKEGPVGLPGIDGRPGP------IGPAGARGEPGNIGFP-------GPKGPTGDPGKN 507

Query: 188 DRKFQLHQTPARGPPFPGISGMTRGPVVLSGV--NRQHRWPPGASPSRSLGEAGGERPAR 245
             K       ARG P P  +   +GP    GV   +  + PPG  P    G  G   PA 
Sbjct: 508 GDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPG--PPGFQGLPGPSGPAG 565

Query: 246 ALRRPRAPGRAGGGGPPGGGIPACSIGP 273
            + +P   G  G  G PG   P    GP
Sbjct: 566 EVGKPGERGLHGEFGLPGPAGPRGERGP 593



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 79/295 (26%), Positives = 102/295 (34%), Gaps = 46/295 (15%)

Query: 6    RSPAPGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAPD 65
            R P    G   +TGE          P   A  +G +  A  A  P          +  P 
Sbjct: 819  RGPRGDQGPVGRTGEVGAVG-----PPGFAGEKGPSGEAGTAGPPG---------TPGPQ 864

Query: 66   LLLASRGITGCVNALGHRG-----------SPEAVRGPGRGRGPPNKAGRAA--GSPTRV 112
             LL + GI G   + G RG            P  + GP   RGPP   G     G+P   
Sbjct: 865  GLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEA 924

Query: 113  QRRPRPLR---PSR-AAPRLRGEE--PSLLRPQLSRRPRALRRSTRVPAAGKGGDR---- 162
             R   P     P R   P  +GE   P  + P       A      V  AGK G+R    
Sbjct: 925  GRDGNPGNDGPPGRDGQPGHKGERGYPGNIGP--VGAAGAPGPHGPVGPAGKHGNRGETG 982

Query: 163  -RAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNR 221
               PV P       GP G  G+  ++    +  + P   P   G +G+ +G   ++G + 
Sbjct: 983  PSGPVGPAGAVGPRGPSGPQGIRGDKGEPGE--KGPRGLPGLKGHNGL-QGLPGIAGHHG 1039

Query: 222  QHRWPPGASPSRSLGEAGGERPARALRR---PRAPGRAGGGGPPGGGIPACSIGP 273
                P    P+   G AG   PA    R   P   G AG  GP G   PA   GP
Sbjct: 1040 DQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGP 1094



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 69/232 (29%), Positives = 83/232 (35%), Gaps = 33/232 (14%)

Query: 71  RGITGCVNALGHRGSPEAVRGPGRG-----RGPPNKAGRAAGSPTRVQRRPR----PLRP 121
           RG  G     G RG+P AV  PG       RG    AG A  +  R     R    P  P
Sbjct: 663 RGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGP 722

Query: 122 SR-AAPRLRGEEPSLLRPQLSRRPRA----LRRSTRVPAAGKGGDRRAPVFPTLVPLHHG 176
           +  A P     +P     + ++ P+     +  +  V AAG  G    P  P       G
Sbjct: 723 NGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPN-GPPGPAGSRGDGG 781

Query: 177 PPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTR--GPVVLSGVNRQHRWPPG-ASPS 232
           PPG +G      R          GPP P GISG     GP    G+    R P G   P 
Sbjct: 782 PPGMTGFPGAAGRT---------GPPGPSGISGPPGPPGPAGKEGL----RGPRGDQGPV 828

Query: 233 RSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIG-PGLARLAALGG 283
              GE G   P          G AG  GPPG   P   +G PG+  L    G
Sbjct: 829 GRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRG 880



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 65/227 (28%), Positives = 82/227 (36%), Gaps = 34/227 (14%)

Query: 68  LASRGITGCVNALGHRGSPEAV-----RGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPS 122
           + SRG +G     G++G P  V      GP    G P + G AAG P          +  
Sbjct: 606 IGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERG-AAGIPGG--------KGE 656

Query: 123 RAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASG 182
           +  P LRGE  +  R      P A+       A G  G+  A   P       G PG  G
Sbjct: 657 KGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGA-AGPAGPAGPRGSPGERG 715

Query: 183 -VGSERDRKFQLHQTPARGPPFPGISGM--TRGPVVLSGVNRQHRWPPGASPSRSLGEAG 239
            VG      F     PA     PG  G    +GP   +GV           P+  +G AG
Sbjct: 716 EVGPAGPNGFA---GPAGAAGQPGAKGERGAKGPKGENGV---------VGPTGPVGAAG 763

Query: 240 GERPARALRRPRAPGRAGGGGPPG-GGIPACSIGPGLARLAALGGLP 285
              PA     P   G  G GGPPG  G P  +   G    + + G P
Sbjct: 764 ---PAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPP 807



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 65/218 (29%), Positives = 76/218 (34%), Gaps = 33/218 (15%)

Query: 83  RGSPEAVRGPGRGRGPPNKAGR-AAGSPTRVQRRPRPLRP----SRAAPRLRGEEPSL-L 136
           R  P   RGP   RGPP   GR     PT     P P  P       A +  G+   L  
Sbjct: 31  RKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP 90

Query: 137 RPQLSRRPRALRRSTRVPA-------AGKGGD--------RRAPVFPTLVPLHHGPPGAS 181
            P     PR    +   P        AG+ G+         R P  P       G PG  
Sbjct: 91  GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKP 150

Query: 182 GVGSERDRKFQLHQTPARG----PPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGE 237
           G   ER     +    ARG    P  PG  G+ RG   L G+  Q   P       + GE
Sbjct: 151 GRPGERG---VVGPQGARGFPGTPGLPGFKGI-RGHNGLDGLKGQPGAPGVKGEPGAPGE 206

Query: 238 AG--GERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
            G  G+  AR L  P   GR G  GP G      S+GP
Sbjct: 207 NGTPGQTGARGL--PGERGRVGAPGPAGARGSDGSVGP 242



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 64/217 (29%), Positives = 71/217 (32%), Gaps = 33/217 (15%)

Query: 67  LLASRGITGCVNALGHRGS-----PEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP 121
           L   RG  G     G RGS     P    GP    GPP   G A G    +         
Sbjct: 218 LPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG-APGPKGEIGAVGNAGPA 276

Query: 122 SRAAPRLRGEEPSLLRPQ-LSRRPRALRRSTRVPAAGKGGDRRAPVFP------------ 168
             A PR     P L  P      P A   +    AAG  G   AP  P            
Sbjct: 277 GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAA 336

Query: 169 --TLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWP 226
             T      G PG +G   E   K +      +GPP P      RGP   +G       P
Sbjct: 337 GATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAG----SAGP 392

Query: 227 PGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG 263
           PG    R      G   +R L  P A GRAG  GPPG
Sbjct: 393 PGPPGLR------GSPGSRGL--PGADGRAGVMGPPG 421



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 44/143 (30%), Positives = 55/143 (38%), Gaps = 31/143 (21%)

Query: 131 EEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRK 190
           EE     P   R PR  R     P  G+ G+      PT  P   GPPG  G+G     +
Sbjct: 27  EETVRKGPAGDRGPRGERGPPGPP--GRDGEDG----PTGPPGPPGPPGPPGLGGNFAAQ 80

Query: 191 FQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGAS----------PSRSLGEAGG 240
           +       +G       G+  GP+ L G     R PPGA+          P+   GE G 
Sbjct: 81  YD-----GKGV------GLGPGPMGLMGP----RGPPGAAGAPGPQGFQGPAGEPGEPGQ 125

Query: 241 ERPARALRRPRAPGRAGGGGPPG 263
             PA A      PG+AG  G PG
Sbjct: 126 TGPAGARGPAGPPGKAGEDGHPG 148



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 69/254 (27%), Positives = 84/254 (33%), Gaps = 32/254 (12%)

Query: 49  TPSLIPRAAIRQSQAPDLLLASRGITGCVNALGHRGSPEAVRGPGR--GRGPPNKAGRA- 105
           TP L     IR     D L   +G  G     G  G+P     PG+   RG P + GR  
Sbjct: 170 TPGLPGFKGIRGHNGLDGL---KGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVG 226

Query: 106 AGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP 165
           A  P   +     + P   A  +    P    P        +        AG  G R   
Sbjct: 227 APGPAGARGSDGSVGPVGPAGPIGSAGPPGF-PGAPGPKGEIGAVGNAGPAGPAGPRGEV 285

Query: 166 VFPTLV-PLHHGPPGASGVGSERDRKFQLHQTPARGPP-FPGISGMTRGPVVLSGVNRQH 223
             P L  P+  GPPG  G       K         G P  PG  G+  GPV  +G     
Sbjct: 286 GLPGLSGPV--GPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIP-GPVGAAGATGAR 342

Query: 224 RWPPGASPSRSLGEAG--GERPARALRRPRAP----------GRAGGGGPPGGGIPACSI 271
                  P+ S GE+G  GE  +   + P  P          G AG  GPPG        
Sbjct: 343 GLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPG-------- 394

Query: 272 GPGLARLAALGGLP 285
            PGL       GLP
Sbjct: 395 PPGLRGSPGSRGLP 408



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 54/224 (24%), Positives = 74/224 (33%), Gaps = 34/224 (15%)

Query: 72  GITGCVNALGHRGSP-----------------EAVRGPGRGRGPPNKAGR--AAGSPTRV 112
           G+TG   A G  G P                 E +RGP   +GP  + G   A G P   
Sbjct: 784 GMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFA 843

Query: 113 -QRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLV 171
            ++ P     +   P   G +  L  P +   P + R    +P          P+     
Sbjct: 844 GEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGS-RGERGLPGVAGAVGEPGPLGIAGP 902

Query: 172 PLHHGPPGASGVGSERDRKFQLHQ--TPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGA 229
           P   GPPGA G         +  +   P    P PG  G         G   +  +P   
Sbjct: 903 PGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGP-PGRDGQP-------GHKGERGYPGNI 954

Query: 230 SPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
            P   +G AG   P   +      G  G  GP G   PA ++GP
Sbjct: 955 GP---VGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGP 995


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 56/202 (27%), Positives = 68/202 (33%), Gaps = 26/202 (12%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGR--AAGSPTRVQRRPRPLRPSRAAPRLR 129
            G  G     GH G P   +G     GPP   GR  A G P  +  + RP  P    P   
Sbjct: 1240 GPPGFKGKTGHPGLP-GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGP 1298

Query: 130  GEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLV--------PLHHGPPGAS 181
              +P                   + A G  GDR A     L         P H GPPG  
Sbjct: 1299 PGQPG---------------PAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEP 1343

Query: 182  GVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGE 241
            G      ++    +    GPP P       G    +G   +   P G   S S+G  G  
Sbjct: 1344 GTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPP 1403

Query: 242  RPARALRRPRAPGRAGGGGPPG 263
             PA     P APG +G  G PG
Sbjct: 1404 GPAGERGHPGAPGPSGSPGLPG 1425



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 65/229 (28%), Positives = 81/229 (35%), Gaps = 41/229 (17%)

Query: 71   RGITGCVNALGHRGSP--EAVRGPGRGRGPPNKAGRAAGSPTRVQRR-------PRPLRP 121
            RG TG     G  G P  E + GP    GP  + G    S  +  +        P P  P
Sbjct: 1107 RGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGP 1166

Query: 122  SRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGAS 181
                 ++    P    PQ  +    +R  + +P  G  G       P   P   GP G  
Sbjct: 1167 PGFPGKVGSPGPP--GPQAEKGSEGIRGPSGLP--GSPG-------PPGPPGIQGPAGLD 1215

Query: 182  GVGSERDRKFQLHQTPA-RGPPF----PGISGMTRGPVVLSGVNRQHRWPPGASPSRSLG 236
            G+   +D K  L   P   GPP     PG  G T  P  L G       P    P  S G
Sbjct: 1216 GLDG-KDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPG-LPGPKGDCGKP---GPPGSTG 1270

Query: 237  EAGGERPARALR---RPRAPGRAGGGGPPGGGIPACSIGPGLARLAALG 282
              G E    A+    RP  PG  G  GPPG         PG A ++A+G
Sbjct: 1271 RPGAEGEPGAMGPQGRPGPPGHVGPPGPPG--------QPGPAGISAVG 1311



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 72/235 (30%), Positives = 89/235 (37%), Gaps = 38/235 (16%)

Query: 67  LLASRGITGCVNA--LGHRGSPEAVRGPGRGRGPPNKAGRA--AGSPTRVQRRPRPLRPS 122
           L++S G +G V +   G  G P     PG  +G     G A  AGSP      P P+ P 
Sbjct: 568 LVSSTGASGDVGSPGFGLPGLPGRAGVPGL-KGEKGNFGEAGPAGSPGP----PGPVGP- 621

Query: 123 RAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPA-AGKGGDRRAPVFPTLVPLHHGPPGAS 181
            A  +    EP    P LS       R   +P  +G+ G+   P F        G PG  
Sbjct: 622 -AGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF--------GLPGKQ 672

Query: 182 GVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAG-G 240
           G   ER  K Q  +  A  P  PG  G T  P  LSG       P    P+   GE G G
Sbjct: 673 GKAGERGLKGQ--KGDAGNPGDPGTPGTTGRPG-LSGE------PGVQGPAGPKGEKGDG 723

Query: 241 ERPARALR--------RPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSI 287
                +L+        RP  PG  G  GP G G P     PGL  +    GL  +
Sbjct: 724 CTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGV 778



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 64/250 (25%), Positives = 81/250 (32%), Gaps = 43/250 (17%)

Query: 71  RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSR-----AA 125
           RG+ G     G+ G P          G P   GR   S     + P   +  +     A 
Sbjct: 678 RGLKGQKGDAGNPGDP----------GTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTAC 727

Query: 126 PRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGS 185
           P L+G    +        P+  +    V   GK G    P  P +     GPPG  GV  
Sbjct: 728 PSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQ---PGLPGV----QGPPGLKGVQG 780

Query: 186 ERD---RKFQLHQTPARGPPFPGISGMT--RGPVVLSGVNRQHR-----------WPPGA 229
           E     R  Q  Q     P  PGI G+   RGP   +G                  PPGA
Sbjct: 781 EPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGA 840

Query: 230 SPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSI-GPGLARLAALGGLPSIL 288
           S S   G  G +        P   G  G  G PG     CS    G    + + G P + 
Sbjct: 841 SVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPG----ECSCPSQGDLIFSGMPGAPGLW 896

Query: 289 ESSRLLPSPR 298
             S   P P+
Sbjct: 897 MGSSWQPGPQ 906



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 35/110 (31%), Positives = 41/110 (37%), Gaps = 17/110 (15%)

Query: 165  PVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPF-PGISGMTRGPVVLSGVNRQH 223
            P+ P   P   G PG  G+  ER            GPP  PG  G T GP  L G+  + 
Sbjct: 1049 PIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGAT-GPPGLPGIKGER 1107

Query: 224  RWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
             +      + S GE G          P  PG  G  GPPG   P    GP
Sbjct: 1108 GY------TGSAGEKG---------EPGPPGSEGLPGPPGPAGPRGERGP 1142



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 29/100 (29%), Positives = 36/100 (36%), Gaps = 17/100 (17%)

Query: 176 GPPGASGVGSERDRKFQLHQTPARGPPF-PGISGMTRGPVVLSGVNRQHRWPPGASPSRS 234
           GP G  G   E+ +K +      +G P  PG  G   G + + G   Q   P    P   
Sbjct: 387 GPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRP-GEICVIGPKGQKGDPGFVGPEGL 445

Query: 235 LGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPG 274
            GE               PG  G  GPPG G+P     PG
Sbjct: 446 AGE---------------PGPPGLPGPPGIGLPGTPGDPG 470



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 55/232 (23%), Positives = 75/232 (32%), Gaps = 64/232 (27%)

Query: 68  LASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPR 127
           L   G+ G     G +G     +G G  +G P K GR            RP       P+
Sbjct: 386 LGPSGLPGSTGEKGQKGE----KGDGGIKGVPGKPGRDG----------RPGEICVIGPK 431

Query: 128 LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSER 187
            +  +P  + P+                 G  G+   P  P       GPPG    G+  
Sbjct: 432 GQKGDPGFVGPE-----------------GLAGEPGPPGLP-------GPPGIGLPGTPG 467

Query: 188 DRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRS--LGEAGGE---- 241
           D           GPP P      +G    SG+  +    PG  P +    GE G      
Sbjct: 468 D---------PGGPPGP------KGDKGSSGIPGKEG--PGGKPGKPGVKGEKGDPCEVC 510

Query: 242 --RPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESS 291
              P         PG+ G  G PG  +PA    PG+  +    G P +  SS
Sbjct: 511 PTLPEGFQNFVGLPGKPGPKGEPGDPVPARG-DPGIQGIKGEKGEPCLSCSS 561



 Score = 28.9 bits (63), Expect = 5.9
 Identities = 51/209 (24%), Positives = 75/209 (35%), Gaps = 23/209 (11%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGR-----GPPNKAGRAA--GSPTRVQRRPRPLRPSRA 124
            G  G     G +G      GPG+       GPP  AG     G+P        P  P   
Sbjct: 1371 GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM 1430

Query: 125  APRLRGEE-PSLLRPQLSRR--PRALRRSTRVP-----AAGKGGDRRAPVFPTLVPLHHG 176
               +  +E    +R ++ +    R    ++R+      AA  G  R  P      P   G
Sbjct: 1431 GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPG--RPGPPGKDGAPGRPG 1488

Query: 177  PPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWP--PGASPSRS 234
             PG+ G+  +  R+ +      RG   PG  G  +G + + G+  ++  P  PG      
Sbjct: 1489 APGSPGLPGQIGREGRQGLPGVRG--LPGTKG-EKGDIGI-GIAGENGLPGPPGPQGPPG 1544

Query: 235  LGEAGGERPARALRRPRAPGRAGGGGPPG 263
             G+ G   P      P  PG  G  G PG
Sbjct: 1545 YGKMGATGPMGQQGIPGIPGPPGPMGQPG 1573


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 64/230 (27%), Positives = 79/230 (34%), Gaps = 31/230 (13%)

Query: 50   PSLIPRAAIRQSQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSP 109
            P L  R      Q P     ++G  G   A G  GSP     PG    P  K       P
Sbjct: 1274 PGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGP 1333

Query: 110  --TRVQRRPRPLRPSRAAPR--LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP 165
                 +R PR  +    AP   + GE P L            R+    P+   G     P
Sbjct: 1334 RGDPGERGPRGPKGEPGAPGQVIGGEGPGL----------PGRKGDPGPSGPPG-----P 1378

Query: 166  VFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRW 225
              P   P   GPPG  G   + D+         RGPP PG  G+  G   L G+      
Sbjct: 1379 RGPLGDPGPRGPPGLPGTAMKGDK----GDRGERGPPGPGEGGIAPGEPGLPGL------ 1428

Query: 226  PPGASPSRSLGEAG--GERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
            P    P   +G  G  GE+       P  PG+ G  G  G   P  +IGP
Sbjct: 1429 PGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGP 1478



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 78/317 (24%), Positives = 103/317 (32%), Gaps = 56/317 (17%)

Query: 8    PAPGLGGSK-----KTGEKRPAQTLQRTPRKHAA------SRGQAQAAAAALTPSLIPRA 56
            P PGL G +     K  +  P     + P+           RG+         P L    
Sbjct: 2099 PGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGER 2158

Query: 57   AIRQSQAPDLLLASRGITGCVNALGHRGSPEAV--------RGPGRGRGPPNKAG---RA 105
             +   +    L   RG  G V   G  G P A         +GP   +G P + G   R 
Sbjct: 2159 GMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRG 2218

Query: 106  AGSPTRVQRRPRPLRPS-----RAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGG 160
               PT     P P  PS     + +P L G+     +P    R  A         +GK G
Sbjct: 2219 LTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGA---------SGKDG 2269

Query: 161  DRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVN 220
            DR +P          G PG+ G+      K +   T A G    G+ G         G+ 
Sbjct: 2270 DRGSP----------GVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA 2319

Query: 221  RQHRWPPGASPSRSL----------GEAGGERPARALRRPRAPGRAGGGGPPGGGIPACS 270
                  PGA   R L          G AG         +  APG  G  G PG G+P   
Sbjct: 2320 GDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSP 2379

Query: 271  IGPGLARLAALGGLPSI 287
              PG   +    GLP +
Sbjct: 2380 GPPGPPGVKGDLGLPGL 2396



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 68/233 (29%), Positives = 83/233 (35%), Gaps = 33/233 (14%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGS--PTRVQRRPRPLRPSRAAPRLR 129
            G+ G     G RG P   RGP   +G P   G+  G   P    R+  P       PR  
Sbjct: 1323 GLKGSPGLPGPRGDP-GERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGP 1381

Query: 130  GEEPSLLRPQ-----LSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHH--------G 176
              +P    P        +  +  R     P  G+GG   AP  P L  L          G
Sbjct: 1382 LGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGI--APGEPGLPGLPGSPGPQGPVG 1439

Query: 177  PPGASGV-GSERDRKFQLHQTPA-------RGPPFP----GISGMTRGPVVLSGVNRQHR 224
            PPG  G  G   D    L   P        RGPP      G  G   GP+  +G  +  R
Sbjct: 1440 PPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP-GPLGEAG-EKGER 1497

Query: 225  WPPGASPSRSLGEAGGERPARALRRPRAP-GRAGGGGPPGGGIPACSIGPGLA 276
             PPG + SR L    G   A+    P  P GR G  G PG       +GP +A
Sbjct: 1498 GPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVA 1550



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 73/236 (30%), Positives = 91/236 (38%), Gaps = 38/236 (16%)

Query: 71   RGITGCVNALGHRGSPEAVRGPGRG-RGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLR 129
            RG  G +   G  G P  V  PG+G  G P   G          +  + L   R    LR
Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERG---LR 1933

Query: 130  GEEPSLLRPQLSR-------RPRALRRSTRVPAAGKGGDRRAPVF---PTLVPLHHGPPG 179
            GE  S+  P + R       +  ALR          G     P     P       GPPG
Sbjct: 1934 GEPGSV--PNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPG 1991

Query: 180  ASG-VG--SERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWP--PGASPSRS 234
              G +G   ER  K        +GPP  G++   RGP   SG+  +   P  PG  P R+
Sbjct: 1992 KEGPIGFPGERGLKGDRGDPGPQGPP--GLALGERGPPGPSGLAGEPGKPGIPGL-PGRA 2048

Query: 235  --LGEAG--GERPARALRRPRA-------PGRAGGGGPPGGGIPACSI---GPGLA 276
              +GEAG  GER  R  +  R        PG  G  GPPG   P  S+   GPGL+
Sbjct: 2049 GGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLS 2104



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 73/254 (28%), Positives = 93/254 (36%), Gaps = 54/254 (21%)

Query: 64   PDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPR------ 117
            P L L  RG  G     G  G P     PGR  G   +AGR      R ++  R      
Sbjct: 2017 PGLALGERGPPGPSGLAGEPGKPGIPGLPGRA-GGVGEAGRPGERGERGEKGERGEQGRD 2075

Query: 118  --------PLRPSRAAPRLRGEEPSLLRPQLS--RRPRALRRSTRVPAAGKGGDRRAPVF 167
                    P  P    P++  +EP    P LS  + P  L+ +   P  G  GD+     
Sbjct: 2076 GPPGLPGTPGPPGPPGPKVSVDEPG---PGLSGEQGPPGLKGAKGEP--GSNGDQ----- 2125

Query: 168  PTLVPLHHGPPGASGV-GSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWP 226
                    GP G  GV G + DR     +     P  PG  GM  GP    G+ +  R P
Sbjct: 2126 --------GPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMA-GPEGKPGL-QGPRGP 2175

Query: 227  PGASPSRSLGEAGGERPARALRRPRAP-------GRAGGGGPPGGGI--PACSIG----P 273
            PG  P    G+  G   A  L  P  P       G  G  GPPG G+  P  ++G    P
Sbjct: 2176 PG--PVGGHGDP-GPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPP 2232

Query: 274  GLARLAALGGLPSI 287
            G + L    G P +
Sbjct: 2233 GPSGLVGPQGSPGL 2246



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 63/210 (30%), Positives = 74/210 (35%), Gaps = 18/210 (8%)

Query: 70   SRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAA--GSPTRVQ-RRPRPLRPSRA-- 124
            S G+ G    LG +G P A   PG   G P K G     G    V    PR L+  R   
Sbjct: 2573 SAGLPGLRGLLGPQGQPGAAGIPG-DPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVK 2631

Query: 125  -APRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGV 183
             A  L GE+          RP        +   G  G   AP    L+    GP G  G 
Sbjct: 2632 GACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLI----GPKGDRGF 2687

Query: 184  GSERDRKFQLHQTPARGPP----FPGISGM--TRGPVVLSGVNRQHRWPPGASPSRSLGE 237
              +   K    +   RG P    FPG SG   + GP    G +   R P G    +    
Sbjct: 2688 DGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPG-SVGPRGPEGLQGQKGERG 2746

Query: 238  AGGERPARALRRPRAPGRAGGGGPPGGGIP 267
              GER   A   P APG  G  G PG   P
Sbjct: 2747 PPGERVVGAPGVPGAPGERGEQGRPGPAGP 2776



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 63/227 (27%), Positives = 75/227 (33%), Gaps = 48/227 (21%)

Query: 72   GITGCVNALGHRGSPEAV-------RGPGRGRGPPNKAGRA-----AGSPTRVQRRPRPL 119
            G  G     G RG P  V       +G    RGP    GRA     +G P       RP 
Sbjct: 1563 GPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPG 1622

Query: 120  RPSRAAPRLR-------GEEPSLLRPQLSRRP--RALRRSTRVPA-AGKGGDRRAPVFPT 169
             P    PR R       G+E     P L  +   R LR +  V    G+ GD+  P    
Sbjct: 1623 PPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDG 1682

Query: 170  LVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGV---NRQHRWP 226
                 +G PG+SG   +R            GPP P    +  GP         +R    P
Sbjct: 1683 ----RNGSPGSSGPKGDRGEP---------GPPGPPGRLVDTGPGAREKGEPGDRGQEGP 1729

Query: 227  PGASPSRSLGEAGGERPARALRRPRAP----------GRAGGGGPPG 263
             G      L  A GER     R P  P          G  G  GPPG
Sbjct: 1730 RGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPG 1776



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 75/250 (30%), Positives = 94/250 (37%), Gaps = 42/250 (16%)

Query: 70   SRGITGCVNALGHRGSP--EAVRGPGRGRGPPNKAGRAA-GSPTRVQRRPRPL-RPSRAA 125
            S G+ G V   G  G+P  +   G    RG P   G      P   +  P P   P +A 
Sbjct: 2243 SPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAV 2302

Query: 126  ---PRLRGEE--PSLLRPQLSRRPRALR-RSTRVPAAGKGGDRRAPVFPTLVPLHHGPPG 179
               P  +GE+  P  L   L   P A   R    P   KG   RA       P   G  G
Sbjct: 2303 VGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGD--PGEDGQKG 2360

Query: 180  ASGV-GSERDRKFQLHQTPARGPPFP-------GISGMTRGPVVLSGVNRQHRWPPGASP 231
            A G  G + D    +  +P  GPP P       G+ G+   P V+        +P    P
Sbjct: 2361 APGPKGFKGDPGVGVPGSP--GPPGPPGVKGDLGLPGLPGAPGVVG-------FPGQTGP 2411

Query: 232  SRSLGEAG--GERPARALRRPRAPGRAGGGGPPGGGIPACSIG-PGLARLAALGGLPSIL 288
               +G+ G  GER    L  P  PGR G  GP G   P  S+G PG + L    G P + 
Sbjct: 2412 RGEMGQPGPSGER---GLAGP--PGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV- 2465

Query: 289  ESSRLLPSPR 298
                 LP PR
Sbjct: 2466 ----GLPGPR 2471



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 34/100 (34%), Positives = 43/100 (43%), Gaps = 22/100 (22%)

Query: 177  PPGASGVGSERDRKFQLHQTPARGPPF-PGISGMTRGPVVLSGVNRQHRWPPGASPSRSL 235
            P G  G   E   + Q+      GPP  PG+ G T  P          + PPG++ ++  
Sbjct: 1252 PKGQKGEPGEMGLRGQV------GPPGDPGLPGRTGAP--------GPQGPPGSATAK-- 1295

Query: 236  GEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGL 275
            GE G      A  RP +PGRAG  G PG   P     PGL
Sbjct: 1296 GERGFPG---ADGRPGSPGRAGNPGTPGA--PGLKGSPGL 1330



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 2/67 (2%)

Query: 70   SRGITGCVNALGHRGSPEAVRGPGRGRGPPN-KAGRAAGSPTRVQRRPRPLRPSRAAPRL 128
            S G  G   ++G RG PE ++G    RGPP  +   A G P     R    RP  A PR 
Sbjct: 2720 SAGPPGPPGSVGPRG-PEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRG 2778

Query: 129  RGEEPSL 135
               E +L
Sbjct: 2779 EKGEAAL 2785


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 63/238 (26%), Positives = 81/238 (34%), Gaps = 40/238 (16%)

Query: 72  GITGCVNALGHRGSP-----EAVRGPGRGRGPPNKAGRA-----AGSPTRVQRR----PR 117
           G  G     G +G+P       V GP   RGPP   G+      AG P +   R    P+
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 118 PLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP--VFPTLVPLHH 175
             R     P L G +     P L               +G  G+  +P  + P  +P   
Sbjct: 273 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 332

Query: 176 GPPGASGVGSERDRKFQLHQT-------PARGPPFPGISGMTRGPVVLSGVNRQHRWPPG 228
           G  G +G    R    Q           PA GP FPG  G  +G                
Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG-AKGE--------------- 376

Query: 229 ASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGPGLARLAALGGLP 285
           A P+ + G  G + P      P +PG AG  G PG  GIP      G   +A   G P
Sbjct: 377 AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 64/224 (28%), Positives = 85/224 (37%), Gaps = 20/224 (8%)

Query: 70  SRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLR 129
           +RG  G V  +G    P   RG    RG P + G A       +R P  L   + A    
Sbjct: 493 ARGEPGGVGPIG----PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 548

Query: 130 GE--EPSLLRPQ-LSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
           G   EP L   + L+ RP       +V  +G  G+   P  P       G PG  G    
Sbjct: 549 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR-GQPGVMGFPGP 607

Query: 187 RDRKFQLHQTPARG-PPFPGISGMTR--GPVVLSGVNRQHRWPPG-ASPSRSLGEAGGER 242
           +    +  +   +G P  PG+ G+    G    +G       PPG A P+   GE G   
Sbjct: 608 KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAG-------PPGPAGPAGERGEQGAPG 660

Query: 243 PARALRRPRAPGRAGGGGPPGG-GIPACSIGPGLARLAALGGLP 285
           P+     P  PG  G GG PG  G+P  +  PGL       G P
Sbjct: 661 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 704



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 66/216 (30%), Positives = 80/216 (37%), Gaps = 43/216 (19%)

Query: 71  RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAG--RAAGSPTRV-QRRPRPLRPSRAAPR 127
           RG  G     G +G P     PG G G P   G    AG+P  V  R  R     R +P 
Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEG-GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 711

Query: 128 LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSER 187
            +G +           PR L  +      G  G + A   P   P   GPPG  G+  ER
Sbjct: 712 AQGLQG----------PRGLPGTP-----GTDGPKGASG-PAGPPGAQGPPGLQGMPGER 755

Query: 188 ----------DRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGE 237
                     DR     + P   P   G  G+T GP+   G       P GA+  +  GE
Sbjct: 756 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT-GPIGPPG-------PAGANGEK--GE 805

Query: 238 AGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
            G   PA +     APG  G  GPPG   PA   GP
Sbjct: 806 VGPPGPAGSAGARGAPGERGETGPPG---PAGFAGP 838



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 59/213 (27%), Positives = 73/213 (34%), Gaps = 49/213 (23%)

Query: 62   QAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP 121
            Q P      +G TG     G RG+    +GP    G P  AGR    P      P P  P
Sbjct: 866  QGPSGAPGPQGPTGVTGPKGARGA----QGPPGATGFPGAAGRVG--PPGSNGNPGPPGP 919

Query: 122  SRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGAS 181
                P   G++           P+  R  +  P        + P  P   P   G PG  
Sbjct: 920  ----PGPSGKDG----------PKGARGDSGPPGRAGEPGLQGPAGP---PGEKGEPGDD 962

Query: 182  GVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240
            G               A GPP P G++G  RG V L G   +  +P    PS   G+ G 
Sbjct: 963  GPSG------------AEGPPGPQGLAGQ-RGIVGLPGQRGERGFPGLPGPSGEPGKQG- 1008

Query: 241  ERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
                       APG +G  GPPG   P    GP
Sbjct: 1009 -----------APGASGDRGPPGPVGPPGLTGP 1030



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 58/206 (28%), Positives = 70/206 (33%), Gaps = 24/206 (11%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPL-RPSRAAPR-LR 129
            G+TG     G  GSP A   PGR      K  R           P P   P  A P   +
Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085

Query: 130  GE--EPSLLRPQLSRRPRALR--RSTRVPAAGKG-----GDRRAPVFPTLVPLHHGPPGA 180
            G+  E     P     P   R  +  + P   KG     G+R          L  G PG 
Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL-QGLPGP 1144

Query: 181  SGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240
             G   ++        +  RGPP         GPV  SG +  +  P    P    G +G 
Sbjct: 1145 PGPSGDQGASGPAGPSGPRGPP---------GPVGPSGKDGANGIPGPIGPPGPRGRSGE 1195

Query: 241  ERPARALRRPRAPGRAGGGGPPGGGI 266
              PA     P  PG  G  GPPG GI
Sbjct: 1196 TGPAGP---PGNPGPPGPPGPPGPGI 1218



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 66/229 (28%), Positives = 84/229 (36%), Gaps = 25/229 (10%)

Query: 62  QAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP 121
           Q P  L  + G  G   A G  G P A +GP   +G P + G A  +  +  R     + 
Sbjct: 716 QGPRGLPGTPGTDGPKGASGPAGPPGA-QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG 774

Query: 122 SRAAPRLRGEE--PSLLRPQLSRRPRALRRSTRVPA-AGKGGDRRAP-----VFPTLVPL 173
              AP   G       + P         +     P  AG  G R AP       P     
Sbjct: 775 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 834

Query: 174 HHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMT--RGPVVLSGVN--RQHRWPPG 228
             GPPGA G    +  + +  Q    G P P G SG    +GP  ++G    R  + PPG
Sbjct: 835 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 894

Query: 229 ASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLAR 277
           A+     G AG   P         PG  G  GPPG   P+   GP  AR
Sbjct: 895 ATGFP--GAAGRVGP---------PGSNGNPGPPGPPGPSGKDGPKGAR 932



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 66/251 (26%), Positives = 77/251 (30%), Gaps = 51/251 (20%)

Query: 64   PDLLLASRGITGCVNALGHRGSP-----------EAVRGPGRGRGPPNKAGRA-----AG 107
            P  L   RGI G     G RG P           +   G    RGPP   G       AG
Sbjct: 973  PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAG 1032

Query: 108  SPTRVQRRPRPLRPSR-AAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDR---- 162
             P R         P R  A  ++G+            P            GK GDR    
Sbjct: 1033 EPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1092

Query: 163  -RAPVFPTLVPLHHGPPGASGV-------------GSERDRKFQLHQ-----TPARGPPF 203
             + P+ P+      GP GA G+             G   +R  + H+         GPP 
Sbjct: 1093 AQGPMGPS------GPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1146

Query: 204  PGISGMTRGPVVLSGVNRQHRWPPG-ASPSRSLGEAGGERPARALRRPRAPGRAGGGGPP 262
            P       GP   SG     R PPG   PS   G  G   P          G  G  GPP
Sbjct: 1147 PSGDQGASGPAGPSGP----RGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1202

Query: 263  GGGIPACSIGP 273
            G   P    GP
Sbjct: 1203 GNPGPPGPPGP 1213



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 66/224 (29%), Positives = 81/224 (36%), Gaps = 43/224 (19%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAA-PRLRG 130
            G TG   A G  G P +   PG   GPP  +G+      R    P    P RA  P L+G
Sbjct: 894  GATGFPGAAGRVGPPGSNGNPGPP-GPPGPSGKDGPKGARGDSGP----PGRAGEPGLQG 948

Query: 131  E--------EPSLLRPQLSRRPRALR----RSTRVPAAGKGGDRRAPVFP--TLVPLHHG 176
                     EP    P  +  P   +    +   V   G+ G+R  P  P  +  P   G
Sbjct: 949  PAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG 1008

Query: 177  PPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHR--WPPGASPSR 233
             PGASG                RGPP P G  G+T GP    G         PPG   + 
Sbjct: 1009 APGASG---------------DRGPPGPVGPPGLT-GPAGEPGREGSPGADGPPGRDGAA 1052

Query: 234  SL----GEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
             +    GE G      A   P +PG AG  G  G    A + GP
Sbjct: 1053 GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 61/227 (26%), Positives = 78/227 (34%), Gaps = 55/227 (24%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEE-------- 132
           G +G P  ++     +GPP   G A     R  R     +  + AP  RG +        
Sbjct: 104 GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD---KGEKGAPGPRGRDGEPGTPGN 160

Query: 133 PSLLRPQLSRRPRALRRSTRVPAAG-----KGGDRRAPVFPTLVPL-HHGPPGASGVGSE 186
           P    P     P  L  +     AG      GG +   +   + P+   GPPG +G    
Sbjct: 161 PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 220

Query: 187 RDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPG--ASPSRSLGEAGGERPA 244
                Q  Q     P  PG+SG   GP          R PPG    P    GEAG     
Sbjct: 221 -----QGFQGNPGEPGEPGVSG-PMGP----------RGPPGPPGKPGDD-GEAG----- 258

Query: 245 RALRRPRAPGRAGGGGPPG----GGIPACSIGPGLARLAALGGLPSI 287
                   PG+AG  GPPG     G P     PGL  +    G P +
Sbjct: 259 -------KPGKAGERGPPGPQGARGFPGT---PGLPGVKGHRGYPGL 295



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 29/99 (29%), Positives = 35/99 (35%), Gaps = 17/99 (17%)

Query: 165 PVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHR 224
           P+ PT +    G PG  G   E      +     +GPP P      +GP    G      
Sbjct: 87  PICPTDLATASGQPGPKGQKGEPGDIKDI--VGPKGPPGP------QGPAGEQG------ 132

Query: 225 WPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG 263
            P G    +  GE G   P      P  PG  G  GPPG
Sbjct: 133 -PRGDRGDK--GEKGAPGPRGRDGEPGTPGNPGPPGPPG 168


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 63/238 (26%), Positives = 81/238 (34%), Gaps = 40/238 (16%)

Query: 72  GITGCVNALGHRGSP-----EAVRGPGRGRGPPNKAGRA-----AGSPTRVQRR----PR 117
           G  G     G +G+P       V GP   RGPP   G+      AG P +   R    P+
Sbjct: 144 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 118 PLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP--VFPTLVPLHH 175
             R     P L G +     P L               +G  G+  +P  + P  +P   
Sbjct: 204 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263

Query: 176 GPPGASGVGSERDRKFQLHQT-------PARGPPFPGISGMTRGPVVLSGVNRQHRWPPG 228
           G  G +G    R    Q           PA GP FPG  G  +G                
Sbjct: 264 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG-AKGE--------------- 307

Query: 229 ASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGPGLARLAALGGLP 285
           A P+ + G  G + P      P +PG AG  G PG  GIP      G   +A   G P
Sbjct: 308 AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 64/224 (28%), Positives = 85/224 (37%), Gaps = 20/224 (8%)

Query: 70  SRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLR 129
           +RG  G V  +G    P   RG    RG P + G A       +R P  L   + A    
Sbjct: 424 ARGEPGGVGPIG----PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 479

Query: 130 GE--EPSLLRPQ-LSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
           G   EP L   + L+ RP       +V  +G  G+   P  P       G PG  G    
Sbjct: 480 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR-GQPGVMGFPGP 538

Query: 187 RDRKFQLHQTPARG-PPFPGISGMTR--GPVVLSGVNRQHRWPPG-ASPSRSLGEAGGER 242
           +    +  +   +G P  PG+ G+    G    +G       PPG A P+   GE G   
Sbjct: 539 KGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAG-------PPGPAGPAGERGEQGAPG 591

Query: 243 PARALRRPRAPGRAGGGGPPGG-GIPACSIGPGLARLAALGGLP 285
           P+     P  PG  G GG PG  G+P  +  PGL       G P
Sbjct: 592 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 635



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 66/216 (30%), Positives = 80/216 (37%), Gaps = 43/216 (19%)

Query: 71  RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAG--RAAGSPTRV-QRRPRPLRPSRAAPR 127
           RG  G     G +G P     PG G G P   G    AG+P  V  R  R     R +P 
Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEG-GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 642

Query: 128 LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSER 187
            +G +           PR L  +      G  G + A   P   P   GPPG  G+  ER
Sbjct: 643 AQGLQG----------PRGLPGTP-----GTDGPKGASG-PAGPPGAQGPPGLQGMPGER 686

Query: 188 ----------DRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGE 237
                     DR     + P   P   G  G+T GP+   G       P GA+  +  GE
Sbjct: 687 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT-GPIGPPG-------PAGANGEK--GE 736

Query: 238 AGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
            G   PA +     APG  G  GPPG   PA   GP
Sbjct: 737 VGPPGPAGSAGARGAPGERGETGPPG---PAGFAGP 769



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 59/213 (27%), Positives = 73/213 (34%), Gaps = 49/213 (23%)

Query: 62  QAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP 121
           Q P      +G TG     G RG+    +GP    G P  AGR    P      P P  P
Sbjct: 797 QGPSGAPGPQGPTGVTGPKGARGA----QGPPGATGFPGAAGRVG--PPGSNGNPGPPGP 850

Query: 122 SRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGAS 181
               P   G++           P+  R  +  P        + P  P   P   G PG  
Sbjct: 851 ----PGPSGKDG----------PKGARGDSGPPGRAGEPGLQGPAGP---PGEKGEPGDD 893

Query: 182 GVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240
           G               A GPP P G++G  RG V L G   +  +P    PS   G+ G 
Sbjct: 894 GPSG------------AEGPPGPQGLAGQ-RGIVGLPGQRGERGFPGLPGPSGEPGKQG- 939

Query: 241 ERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
                      APG +G  GPPG   P    GP
Sbjct: 940 -----------APGASGDRGPPGPVGPPGLTGP 961



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 58/206 (28%), Positives = 70/206 (33%), Gaps = 24/206 (11%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPL-RPSRAAPR-LR 129
            G+TG     G  GSP A   PGR      K  R           P P   P  A P   +
Sbjct: 957  GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016

Query: 130  GE--EPSLLRPQLSRRPRALR--RSTRVPAAGKG-----GDRRAPVFPTLVPLHHGPPGA 180
            G+  E     P     P   R  +  + P   KG     G+R          L  G PG 
Sbjct: 1017 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL-QGLPGP 1075

Query: 181  SGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240
             G   ++        +  RGPP         GPV  SG +  +  P    P    G +G 
Sbjct: 1076 PGPSGDQGASGPAGPSGPRGPP---------GPVGPSGKDGANGIPGPIGPPGPRGRSGE 1126

Query: 241  ERPARALRRPRAPGRAGGGGPPGGGI 266
              PA     P  PG  G  GPPG GI
Sbjct: 1127 TGPAGP---PGNPGPPGPPGPPGPGI 1149



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 66/229 (28%), Positives = 84/229 (36%), Gaps = 25/229 (10%)

Query: 62  QAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP 121
           Q P  L  + G  G   A G  G P A +GP   +G P + G A  +  +  R     + 
Sbjct: 647 QGPRGLPGTPGTDGPKGASGPAGPPGA-QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG 705

Query: 122 SRAAPRLRGEE--PSLLRPQLSRRPRALRRSTRVPA-AGKGGDRRAP-----VFPTLVPL 173
              AP   G       + P         +     P  AG  G R AP       P     
Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 765

Query: 174 HHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMT--RGPVVLSGVN--RQHRWPPG 228
             GPPGA G    +  + +  Q    G P P G SG    +GP  ++G    R  + PPG
Sbjct: 766 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 825

Query: 229 ASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLAR 277
           A+     G AG   P         PG  G  GPPG   P+   GP  AR
Sbjct: 826 ATGFP--GAAGRVGP---------PGSNGNPGPPGPPGPSGKDGPKGAR 863



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 66/251 (26%), Positives = 77/251 (30%), Gaps = 51/251 (20%)

Query: 64   PDLLLASRGITGCVNALGHRGSP-----------EAVRGPGRGRGPPNKAGRA-----AG 107
            P  L   RGI G     G RG P           +   G    RGPP   G       AG
Sbjct: 904  PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAG 963

Query: 108  SPTRVQRRPRPLRPSR-AAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDR---- 162
             P R         P R  A  ++G+            P            GK GDR    
Sbjct: 964  EPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1023

Query: 163  -RAPVFPTLVPLHHGPPGASGV-------------GSERDRKFQLHQ-----TPARGPPF 203
             + P+ P+      GP GA G+             G   +R  + H+         GPP 
Sbjct: 1024 AQGPMGPS------GPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPG 1077

Query: 204  PGISGMTRGPVVLSGVNRQHRWPPG-ASPSRSLGEAGGERPARALRRPRAPGRAGGGGPP 262
            P       GP   SG     R PPG   PS   G  G   P          G  G  GPP
Sbjct: 1078 PSGDQGASGPAGPSGP----RGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1133

Query: 263  GGGIPACSIGP 273
            G   P    GP
Sbjct: 1134 GNPGPPGPPGP 1144



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 66/224 (29%), Positives = 81/224 (36%), Gaps = 43/224 (19%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAA-PRLRG 130
            G TG   A G  G P +   PG   GPP  +G+      R    P    P RA  P L+G
Sbjct: 825  GATGFPGAAGRVGPPGSNGNPGPP-GPPGPSGKDGPKGARGDSGP----PGRAGEPGLQG 879

Query: 131  E--------EPSLLRPQLSRRPRALR----RSTRVPAAGKGGDRRAPVFP--TLVPLHHG 176
                     EP    P  +  P   +    +   V   G+ G+R  P  P  +  P   G
Sbjct: 880  PAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG 939

Query: 177  PPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHR--WPPGASPSR 233
             PGASG                RGPP P G  G+T GP    G         PPG   + 
Sbjct: 940  APGASG---------------DRGPPGPVGPPGLT-GPAGEPGREGSPGADGPPGRDGAA 983

Query: 234  SL----GEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
             +    GE G      A   P +PG AG  G  G    A + GP
Sbjct: 984  GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 61/227 (26%), Positives = 78/227 (34%), Gaps = 55/227 (24%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEE-------- 132
           G +G P  ++     +GPP   G A     R  R     +  + AP  RG +        
Sbjct: 35  GQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD---KGEKGAPGPRGRDGEPGTPGN 91

Query: 133 PSLLRPQLSRRPRALRRSTRVPAAG-----KGGDRRAPVFPTLVPL-HHGPPGASGVGSE 186
           P    P     P  L  +     AG      GG +   +   + P+   GPPG +G    
Sbjct: 92  PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 151

Query: 187 RDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPG--ASPSRSLGEAGGERPA 244
                Q  Q     P  PG+SG   GP          R PPG    P    GEAG     
Sbjct: 152 -----QGFQGNPGEPGEPGVSG-PMGP----------RGPPGPPGKPGDD-GEAG----- 189

Query: 245 RALRRPRAPGRAGGGGPPG----GGIPACSIGPGLARLAALGGLPSI 287
                   PG+AG  GPPG     G P     PGL  +    G P +
Sbjct: 190 -------KPGKAGERGPPGPQGARGFPGT---PGLPGVKGHRGYPGL 226


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 69/243 (28%), Positives = 87/243 (35%), Gaps = 36/243 (14%)

Query: 71   RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP-----SRAA 125
            RG+ G V ALG +G+      PG    P  +    A  P  +  RP P  P      + A
Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGA 1121

Query: 126  PRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDR-----------------RAPVFP 168
            P  +G +    R  L         +  V   G+ GD+                 + P  P
Sbjct: 1122 PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGP 1181

Query: 169  TLVPLHHGPPGASGVGSE---RDRKFQLHQTPARGP-PFPGISGMTRGPVVLSGVNRQHR 224
            T      G PG SG   E   R ++    Q    GP  FPG      GPV L G+     
Sbjct: 1182 TGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPG----PPGPVGLQGL----P 1233

Query: 225  WPPG-ASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGG-GIPACSIGPGLARLAALG 282
             PPG    +  +G+ G   P        APG  G  GPPGG G P      G    A   
Sbjct: 1234 GPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEP 1293

Query: 283  GLP 285
            GLP
Sbjct: 1294 GLP 1296



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 78/298 (26%), Positives = 104/298 (34%), Gaps = 44/298 (14%)

Query: 10  PGLGGSKKTGEKRPAQTLQRTPRKH-----AASRGQAQAAAAALTPSLIPRA--AIRQSQ 62
           PGL G+   G   P  T+   P +      A S+G   +A  +   +++ +A  A+R   
Sbjct: 504 PGLPGAD--GLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPA 561

Query: 63  APDLLLASRGITGCVNALGHRGSP--------EAVRGPGRGRGPPNKAGRAAGSPTRV-- 112
            P  L    G  G   + G +G P          V+GP    G P + GRA     R   
Sbjct: 562 GPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMP 621

Query: 113 -QRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP------ 165
            Q  P+  R       L GE+     P  S  P            G+ G R  P      
Sbjct: 622 GQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPR 681

Query: 166 --VFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPF----PGISGMTRGPVVLSGV 219
             + P   P   GPPG +G+  +   K  +      GPP     PG  G+  GP    G 
Sbjct: 682 GLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLP-GPQGAIG- 739

Query: 220 NRQHRWPPGASPSRSL----GEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
                 PPG           G  G + P     +   PG  GG GPPG   P    GP
Sbjct: 740 ------PPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGP 791



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 58/210 (27%), Positives = 70/210 (33%), Gaps = 22/210 (10%)

Query: 71   RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRG 130
            +G+ G     G RG P    GP   +G P   G    +    Q  P    P    PR   
Sbjct: 1206 QGLFGQKGDEGPRGFP-GPPGPVGLQGLPGPPGEKGETGDVGQMGP----PGPPGPRGPS 1260

Query: 131  EEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRK 190
              P    PQ    P  +     V   G+ G+   P  P       GPPG  G   ER  K
Sbjct: 1261 GAPGADGPQ--GPPGGIGNPGAVGEKGEPGEAGEPGLPG----EGGPPGPKG---ERGEK 1311

Query: 191  FQLHQTPARGPPFP-------GISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERP 243
             +   + A GPP P       G  G + GPV   G       P  A      G+ G +  
Sbjct: 1312 GESGPSGAAGPPGPKGPPGDDGPKG-SPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGE 1370

Query: 244  ARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
                  P   G  G  GPPG   P    GP
Sbjct: 1371 PGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 61/215 (28%), Positives = 76/215 (35%), Gaps = 21/215 (9%)

Query: 64   PDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSR 123
            P  ++  +G TG    +G RG P     PG  +G P  AG+     T+    P  L    
Sbjct: 995  PPGVVGPQGPTGETGPMGERGHPGPPGPPGE-QGLPGLAGKEG---TKGDPGPAGLPGKD 1050

Query: 124  AAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDR--RAPVFPTLVPLHHGPPGAS 181
              P LRG             P        V A G  G+     P  P   P   GP GA+
Sbjct: 1051 GPPGLRG------------FPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAA 1098

Query: 182  G-VGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240
            G +G       Q    PA     PG  G  +GP    G+      P  A P    GE G 
Sbjct: 1099 GPIGIPGRPGPQGPPGPAGEKGAPGEKG-PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGD 1157

Query: 241  ERPARALRRPRAPGRAGGGGPPGGGIPACSIG-PG 274
            +       +  + G  G  GPPG   P   IG PG
Sbjct: 1158 KGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPG 1192



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 66/302 (21%), Positives = 92/302 (30%), Gaps = 49/302 (16%)

Query: 5    PRSPAPGLGGSKKTGEKR----------PAQTLQRTPRKHAASRGQAQAAAAALTPSLIP 54
            P+ P  G+G     GEK           P +     P+     +G++  + AA  P    
Sbjct: 1268 PQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPG--- 1324

Query: 55   RAAIRQSQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQR 114
                   + P      +G  G V   G  G P    GP    GPP   G   G P +   
Sbjct: 1325 ------PKGPPGDDGPKGSPGPVGFPGDPGPP-GEPGPAGQDGPPGDKGDD-GEPGQTGS 1376

Query: 115  RPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAA-GKGGDRRAPVFPTLVPL 173
                  P  + P  +   P    P+  +  +  +    +    GK G    P+ P   P 
Sbjct: 1377 PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG----PIGPQGAPG 1432

Query: 174  HHGPPGASGVGSERDRKFQLHQTPARGPP----------------------FPGISGMTR 211
              GP G  G+      +         GPP                       PG+ G+  
Sbjct: 1433 KPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLI- 1491

Query: 212  GPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSI 271
            GP    G       P     S   GE G   P+  +  P  PG  G  GP G    +   
Sbjct: 1492 GPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPT 1551

Query: 272  GP 273
            GP
Sbjct: 1552 GP 1553



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 53/194 (27%), Positives = 66/194 (34%), Gaps = 16/194 (8%)

Query: 71   RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRG 130
            RG  G     G +G   A +G     GPP K G     P     +P P    R  P   G
Sbjct: 1392 RGPPGPAGPEGRQGEKGA-KGEAGLEGPPGKTGPIG--PQGAPGKPGP-DGLRGIPGPVG 1447

Query: 131  EEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRK 190
            E+     P     P  +         G  G +     P L+ L  GPPG  G   +R   
Sbjct: 1448 EQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLI-GPPGEQGEKGDRGLP 1506

Query: 191  FQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGA-SPSRSLGEAGGERPARALRR 249
                 +  +G    GI+G + GP+   G       PPG   P    G  G   P      
Sbjct: 1507 GPQGSSGPKGEQ--GITGPS-GPIGPPG-------PPGLPGPPGPKGAKGSSGPTGPKGE 1556

Query: 250  PRAPGRAGGGGPPG 263
               PG  G  GPPG
Sbjct: 1557 AGHPGPPGPPGPPG 1570



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 71/252 (28%), Positives = 85/252 (33%), Gaps = 59/252 (23%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAG-RAAGSPT--RVQRRPRPLRPSRAAPRL 128
            G  G   ++G  G P A  G   GRG P K G R    PT  R +R PR +   +  P+ 
Sbjct: 877  GRQGPKGSIGFPGFPGA-NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGIT-GKPGPKG 934

Query: 129  RGEEPSLLRPQLSRRPRALRRSTRVPAA-------GKGG--------------DRRAPVF 167
                     P   R P   +  T  P         GK G               +  P  
Sbjct: 935  NSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 994

Query: 168  PTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPP----FPGISGMTR-----GPVVLSG 218
            P  V    GP G +G   ER      H  P  GPP     PG++G        GP  L G
Sbjct: 995  PPGVVGPQGPTGETGPMGERG-----HPGPP-GPPGEQGLPGLAGKEGTKGDPGPAGLPG 1048

Query: 219  VNRQHRWPPGA----------SPSRSLGEAGGERPARALRRPRAPGR---AGGGGPPG-G 264
             +     PPG            P  +LG  G E P        +PG    AG  GP G  
Sbjct: 1049 KDG----PPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIP 1104

Query: 265  GIPACSIGPGLA 276
            G P     PG A
Sbjct: 1105 GRPGPQGPPGPA 1116



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 42/131 (32%), Positives = 52/131 (39%), Gaps = 38/131 (29%)

Query: 182 GVGSERDRKFQLHQTPA--------RGPPFPGISGMTRGPVVLSGVNRQHRWPPGA-SPS 232
           G+G  R  K Q  + PA         GPP P       GP  L G       PPG   P+
Sbjct: 444 GIGGPRGEKGQKGE-PAIIEPGMLIEGPPGP------EGPAGLPG-------PPGTMGPT 489

Query: 233 RSLGEAGGERPARALRRPRAPGRAGGGGPP----------GGGIPACSIGPGLARLAALG 282
             +G+ G   P     RP  PG  G  GPP          GGG  A S GP ++  A   
Sbjct: 490 GQVGDPGERGPPG---RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVS--AQES 544

Query: 283 GLPSILESSRL 293
              +IL+ +RL
Sbjct: 545 QAQAILQQARL 555


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 51/176 (28%), Positives = 67/176 (38%), Gaps = 25/176 (14%)

Query: 92  PGRGRGPPN---------KAGRAAGSPTRVQRRPRPLRPSRA---APRLRG-EEPSLLRP 138
           P RG+  P+         + GRAAG   R +RR R  R SR+   APR RG   P    P
Sbjct: 357 PARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPP 416

Query: 139 QLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPA 198
           + S R  +  RS+    +G+G     P          G     G   +R ++      PA
Sbjct: 417 RGSSRSLSRARSSSDSGSGRGAPGPGP--------EPGSERGHGGHGKRAKERPPRARPA 468

Query: 199 RGPPFPGISGMTRGPVVLSGVN----RQHRWPPGASPSRSLGEAGGERPARALRRP 250
              P PG  G   GP   S           W    SPS+S   +  +RP    R P
Sbjct: 469 STSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSP 524



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 55/234 (23%), Positives = 90/234 (38%), Gaps = 35/234 (14%)

Query: 11  GLGGSKKTGEKRP--AQTLQRTPRKHA-ASRGQAQAAAAALTPSLIPRAAIRQSQAPDLL 67
           G GG  K  ++RP  A+    +P   A   RG  +  +++ +P   PR+    S++P   
Sbjct: 450 GHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSW-SSSRSPS-- 506

Query: 68  LASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPR 127
             SR  +          SP   +   R +    +A  +    TR +RR R   P R   +
Sbjct: 507 -KSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIR---K 562

Query: 128 LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSER 187
            R + PS + P+            R+ +A     R+ P     +P +   P +S      
Sbjct: 563 RRRDSPSFMEPR------------RITSA-----RKRP-----IPYYRPSPSSSSSCLSS 600

Query: 188 DRKFQLH-QTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240
           D   + H ++P+ G      S  + G    S      R P  +  SRS  E+GG
Sbjct: 601 DYSTRSHSRSPSPGHSHGSYSSRSHG--TRSRTRSPSRTPSPSYHSRSSSESGG 652



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 57/233 (24%), Positives = 77/233 (33%), Gaps = 53/233 (22%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPR-----------PLRPSRAAPRLR 129
           GHRG             PP K  +  G   R +++ R           PLR  + + +  
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209

Query: 130 GEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDR 189
             + S    +  RR R+  RS++     K  +++ P        H   PG         R
Sbjct: 210 RRDRSDSGSRRKRRHRS--RSSKCKRKEKNKEKKRP--------HTESPG---------R 250

Query: 190 KFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPS-RSLGEAGGERPARALR 248
           +   H            SG +  P  LS      R P   SP  R  G   G + +   R
Sbjct: 251 RSHRHS-----------SGSSHSPS-LSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSR 298

Query: 249 RPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILES---SRLLPSPR 298
            P   G +G G P   G      G G  R  A GG P    S       PSPR
Sbjct: 299 SPSPSGGSGWGSPQRNG------GSG-QRSGAHGGRPGSAHSPPDKPSSPSPR 344


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 83/294 (28%), Positives = 98/294 (33%), Gaps = 44/294 (14%)

Query: 5    PRSPAPGLGGSKKTGEK----RPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQ 60
            P  PA   GG    GE     RP +     P   A  +G   A   A  P          
Sbjct: 897  PPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPG--------- 947

Query: 61   SQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLR 120
            +  P  +   RG+ G     G RG P  + GP    G P K G +  S  R    P P+ 
Sbjct: 948  TPGPQGIAGQRGVVGLPGQRGERGFP-GLPGPS---GEPGKQGPSGASGERGP--PGPMG 1001

Query: 121  PSRAA--PRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDR--RAPVFPTLVPLHHG 176
            P   A  P   G E +         P A     R  + G  GDR    P  P   P   G
Sbjct: 1002 PPGLAGPPGESGREGA---------PGAEGSPGRDGSPGAKGDRGETGPAGPPGAP---G 1049

Query: 177  PPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLG 236
             PGA G      +     +T   GP  P      RGP    G  R  +   G    R + 
Sbjct: 1050 APGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGP-RGDKGETGEQGDRGIK 1108

Query: 237  EAGGERPARALRRPRAP-GRAGGGGPPGGGIPACSIGP----GLARLAALGGLP 285
               G R    L+ P  P G  G  GP G   PA   GP    G      L GLP
Sbjct: 1109 ---GHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLP 1159



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 74/240 (30%), Positives = 86/240 (35%), Gaps = 42/240 (17%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGR--AAGSPTRVQRR-----PRPLRPSR- 123
            G TG   A G RG P    GP    GPP   G+  A G P     +     P P  P+  
Sbjct: 791  GPTGARGAPGDRGEP-GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP 849

Query: 124  -------AAPRLRGEEPSLLRPQLSRRPRALRR-------------STRVPAAGKGGDR- 162
                    AP  +G   S   P  +  P A  R                 PA  +GG   
Sbjct: 850  PGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGP 909

Query: 163  RAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNR 221
            R    P   P   GPPG  G   E+          A G P P GI+G  RG V L G   
Sbjct: 910  RGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQ-RGVVGLPGQRG 968

Query: 222  QHRWPPGASPSRSLGEAGGERPARAL--RRPRAP-GRAGGGGPPG----GGIPACSIGPG 274
            +  +P    PS   GE G + P+ A   R P  P G  G  GPPG     G P     PG
Sbjct: 969  ERGFPGLPGPS---GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPG 1025



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 76/253 (30%), Positives = 94/253 (37%), Gaps = 36/253 (14%)

Query: 35  AASRGQAQAAAAALTPSLIPRAAIRQSQAPDLLLASRGITGCVNALGHRGS--PEAVRGP 92
           A +RG   A  AA  P     A       P     + G  G     G RGS  P+ VRG 
Sbjct: 319 AGARGNDGATGAAGPPGPTGPAG------PPGFPGAVGAKGEAGPQGPRGSEGPQGVRGE 372

Query: 93  GRGRGPPNKAGRA--AGSPTRVQRRPRPLRPSRAAPRLRGEE-------PSLLRPQLSRR 143
               GPP  AG A  AG+P     +P   + +  AP + G         PS   PQ    
Sbjct: 373 P---GPPGPAGAAGPAGNPG-ADGQPGA-KGANGAPGIAGAPGFPGARGPS--GPQGPGG 425

Query: 144 PRALRRSTRVPAA-GKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPP 202
           P   + ++  P A G  GD  A   P  V +  GPPG +G   +R  + +   T   GPP
Sbjct: 426 PPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ-GPPGPAGEEGKRGARGEPGPTGLPGPP 484

Query: 203 FPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPP 262
                  +RG     GV         A P    GE G   PA     P   GR G  G P
Sbjct: 485 GERGGPGSRGFPGADGV---------AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535

Query: 263 GG-GIPACSIGPG 274
           G  G+      PG
Sbjct: 536 GAKGLTGSPGSPG 548



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 67/225 (29%), Positives = 79/225 (35%), Gaps = 37/225 (16%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGR-----AAGSPTRV-QRRPRPLRPSRAAPRLRGEEPS 134
           G  G P A  GP   RGPP   G+      AG P R  +R P   + +R  P   G    
Sbjct: 206 GEPGEPGA-SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGM 264

Query: 135 LLRPQLSRRPRALRRSTRVPAAGKG-----GDRRAP--VFPTLVPLHHGPPGASGVGSER 187
                 S    A  +    PA  KG     G+  AP  + P  +P   G PGA G    R
Sbjct: 265 KGHRGFSGLDGA--KGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGAR 322

Query: 188 DRKFQLHQTPARGPP----------FPGISGMT--------RGPVVLSGVNRQHRWPPGA 229
                   T A GPP          FPG  G          RG     GV  +   P  A
Sbjct: 323 GND---GATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379

Query: 230 SPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPG 274
             +   G  G +    A     APG AG  G PG   P+   GPG
Sbjct: 380 GAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 79/295 (26%), Positives = 97/295 (32%), Gaps = 44/295 (14%)

Query: 4   KPRSPAPGLGGSK-KTGEK-RPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQS 61
           K  S  PG  GSK  TG K  P     + P   A   G+  A        L      R  
Sbjct: 430 KGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGG 489

Query: 62  QAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRA--AGSPTRVQRRPRPL 119
                   + G+ G     G RGSP    GP   +G P +AGR   AG P        P 
Sbjct: 490 PGSRGFPGADGVAGPKGPAGERGSP----GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPG 545

Query: 120 RPS----RAAPRLRGEE--PSLLRPQLSRRPRALRRSTRVPAA----GKGGDRRAPVFPT 169
            P        P   G++  P    P  +R    +        A    GK G+R  P    
Sbjct: 546 SPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP---- 601

Query: 170 LVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGA 229
                 GPPGA G   +        +  A+GPP P      RG    +G       P  A
Sbjct: 602 ------GPPGAVGPAGKDG------EAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA 649

Query: 230 SPSRSL---------GEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIG-PG 274
            P             G+ G   P+ A      PG  G  GPPG   P  + G PG
Sbjct: 650 GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPG 704



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 60/221 (27%), Positives = 71/221 (32%), Gaps = 56/221 (25%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE 131
            G+ G     G  G+P A   PGR   P  K  R    P      P        AP   G 
Sbjct: 1004 GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP-------GAPGAPGP 1056

Query: 132  EPSLLRPQLSRRPRALRRSTRVPAAGKGGDR--------RAPVFPTLVPLHHGPPGASG- 182
                                 V  AGK GDR          PV P       GP G  G 
Sbjct: 1057 ---------------------VGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095

Query: 183  ---VGSERDRKFQLHQ--TPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGAS------- 230
                G + DR  + H+  +  +GPP P  S   +GP   SG     R PPG++       
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG-PAGPRGPPGSAGAPGKDG 1154

Query: 231  ------PSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGG 265
                  P    G  G    A  +  P  PG  G  GPP  G
Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 67/219 (30%), Positives = 75/219 (34%), Gaps = 36/219 (16%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPR---- 127
            G TG   A G  G P    G     GPP  AG+  G   R +  P   RP    P     
Sbjct: 872  GATGFPGAAGRVGPP-GPSGNAGPPGPPGPAGKEGGKGPRGETGPAG-RPGEVGPPGPPG 929

Query: 128  LRGEE-----------PSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFP--TLVPLH 174
              GE+           P    PQ     R +     V   G+ G+R  P  P  +  P  
Sbjct: 930  PAGEKGSPGADGPAGAPGTPGPQGIAGQRGV-----VGLPGQRGERGFPGLPGPSGEPGK 984

Query: 175  HGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRS 234
             GP GASG   ER     +      GPP  G SG    P       R     PGA   R 
Sbjct: 985  QGPSGASG---ERGPPGPMGPPGLAGPP--GESGREGAPGAEGSPGRDGS--PGAKGDR- 1036

Query: 235  LGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP 273
             GE G   P  A   P APG  G  GP G        GP
Sbjct: 1037 -GETGPAGPPGA---PGAPGAPGPVGPAGKSGDRGETGP 1071



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 63/226 (27%), Positives = 75/226 (33%), Gaps = 32/226 (14%)

Query: 72  GITGCVNALGHRGSP--EAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLR 129
           G  G   A G RG P    V+GP    GP    G       +          S+ AP L+
Sbjct: 668 GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ 727

Query: 130 GEE-----PSLLRPQLSRRPRALRRSTRVPAAGKGGDR--RAPVFPTLVPLHHGPPGASG 182
           G         L  P+  R     + +   P  GK G R    P+ P       GP GA G
Sbjct: 728 GMPGERGAAGLPGPKGDRGDAGPKGADGSP--GKDGVRGLTGPIGPP------GPAGAPG 779

Query: 183 VGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWP-----PG-------AS 230
              E         T ARG P         GP   +G       P     PG       A 
Sbjct: 780 DKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAG 839

Query: 231 PSRSLGEAGGERPARALRRPRAPGRAGGGGPPGG-GIPACS--IGP 273
           P    G AG   P   +  P A G  G  GPPG  G P  +  +GP
Sbjct: 840 PPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 885



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 66/254 (25%), Positives = 81/254 (31%), Gaps = 59/254 (23%)

Query: 73  ITGCVNALGHRG--SPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRP-------------- 116
           + G +   G RG   P    GP   +GPP + G    S     R P              
Sbjct: 177 VPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAG 236

Query: 117 RPLRPSRAAPRLRGEEPSLLRPQLSRRPRAL----------RRSTRVPAAGKG-----GD 161
           +P RP    P   G + +   P  +  P              +    PA  KG     G+
Sbjct: 237 KPGRPGERGP--PGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294

Query: 162 RRAP--VFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGV 219
             AP  + P  +P   G PGA G    R        T A GPP P       GP    G 
Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPAGARGND---GATGAAGPPGP------TGPAGPPGF 345

Query: 220 NRQHRWPPGASPSRS----LGEAGGERPARALRRPRAPGRAGGGGPPGG----GIPACSI 271
                  PGA  ++      G  G E P      P  PG AG  GP G     G P    
Sbjct: 346 -------PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKG 398

Query: 272 GPGLARLAALGGLP 285
             G   +A   G P
Sbjct: 399 ANGAPGIAGAPGFP 412



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 77/259 (29%), Positives = 89/259 (34%), Gaps = 61/259 (23%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGR--AAGS-----------PTRVQRRPRP 118
           GI G     G RG P   +GPG   GP   +G   A GS           P  VQ  P P
Sbjct: 404 GIAGAPGFPGARG-PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGP 462

Query: 119 L-----RPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAA----GKGGDRRAPVFPT 169
                 R +R  P   G    L  P   R     R            G  G+R +P    
Sbjct: 463 AGEEGKRGARGEPGPTG----LPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSP---- 514

Query: 170 LVPLHHGPPGASGVGSERDRKFQLHQTPARG----PPFPGISGMTRGPVVLSGVNRQHR- 224
                 GP G  G   E  R  +     A+G    P  PG  G T GP   +G + +   
Sbjct: 515 ------GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT-GPPGPAGQDGRPGP 567

Query: 225 -WPPGA----------SPSRSLGEAG--GER----PARALRRPRAPGRAGGGGPPGGGIP 267
             PPGA           P  + GE G  GER    P  A+      G AG  GPPG   P
Sbjct: 568 PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGP 627

Query: 268 ACSIG-PGLARLAALGGLP 285
           A   G  G A      GLP
Sbjct: 628 AGERGEQGPAGSPGFQGLP 646



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 88/296 (29%), Positives = 104/296 (35%), Gaps = 58/296 (19%)

Query: 1   MTAKPRSPAPGLGGSKKTGEKRPA-QTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIR 59
           +T  P SP P      KTG   PA Q  +  P     +RGQA        P   P+ A  
Sbjct: 540 LTGSPGSPGP----DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF---PG--PKGAAG 590

Query: 60  QSQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRA--------AGSPTR 111
           +          RG+ G   A+G  G      G    +GPP  AG A        AGSP  
Sbjct: 591 EPGKA----GERGVPGPPGAVGPAGKD----GEAGAQGPPGPAGPAGERGEQGPAGSPG- 641

Query: 112 VQRRPRPLRPSRAA--PRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDR--RAPVF 167
            Q  P P  P   A  P  +G    L  P     P   R     P     G+R  + P  
Sbjct: 642 FQGLPGPAGPPGEAGKPGEQGVPGDLGAPG----PSGARGERGFP-----GERGVQGPPG 692

Query: 168 PTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPP-FPGISGMT--RGPVVLSGV--NRQ 222
           P       GP GA+G       K       A G    PG+ GM   RG   L G   +R 
Sbjct: 693 PA------GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG 746

Query: 223 HRWPPGASPSRSLGEAGGERPARALRRPRAP-GRAGGGGPPGGGIPACSIGPGLAR 277
              P GA  S       G+   R L  P  P G AG  G  G   P+   GP  AR
Sbjct: 747 DAGPKGADGSP------GKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR 796



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 39/119 (32%), Positives = 44/119 (36%), Gaps = 18/119 (15%)

Query: 149 RSTRVPAAGKGGDRRAPVFPTLV--PLHHGPPGASGVGSE--RDRKFQLHQTPARGPPFP 204
           R  R PA   G D   P  P L   P   GPPG  G+G        +   +    G   P
Sbjct: 120 RGPRGPAGPPGRDG-IPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVP 178

Query: 205 GISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG 263
           G  G + GP  L G       PPGA      G  G + P      P A G  G  GPPG
Sbjct: 179 GPMGPS-GPRGLPG-------PPGAP-----GPQGFQGPPGEPGEPGASGPMGPRGPPG 224



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 33/100 (33%), Positives = 40/100 (40%), Gaps = 12/100 (12%)

Query: 176 GPPGASGVGSERDRKFQLHQTPAR-GPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRS 234
           GPPG  G+  +      L   P   GPP P   G    P +  G + +     G S    
Sbjct: 127 GPPGRDGIPGQPG----LPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTG--GISVPGP 180

Query: 235 LGEAGGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGP 273
           +G +G   P      P APG  G  GPPG  G P  S GP
Sbjct: 181 MGPSG---PRGLPGPPGAPGPQGFQGPPGEPGEPGAS-GP 216


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 97/343 (28%), Positives = 121/343 (35%), Gaps = 67/343 (19%)

Query: 5   PRSPAPGLGGSKKT--GEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQ 62
           PR P P       T    K+P  TL RT  K   S     A+A   T    P  A+  S 
Sbjct: 433 PRPPPPSTRPLPPTTSSSKKPIPTLARTEAK-ITSHASKPASARTSTHKPPPFTALSSSP 491

Query: 63  APD--LLLASRGITGCVNALGHRGSPE---AVRGPGR---GRGPP--NKAGRAAGSPTRV 112
           AP      ++R     V       +P    AV  PG    G   P  ++A + AG P   
Sbjct: 492 APTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAG-PKSS 550

Query: 113 QRRPRPLRPSRAA-----------PRLRGEEPS-LLRPQLSRRP-RALRRSTRVPAAGKG 159
            R+P PLRP +AA           P  R  +PS    P L   P + L  S R  ++G  
Sbjct: 551 PRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYS 610

Query: 160 GDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPP-FPGISGM--TRGPVVL 216
               A   P   PL  GPPG  G                 GPP  PG+ G+   RGP   
Sbjct: 611 IFHLAGSTP--FPLLMGPPGPKG------------DCGLPGPPGLPGLPGIPGARGPRGP 656

Query: 217 SGV-----------NRQHRWPPGASPSRSLGEAGGERPARALR-RPRAPGRAGGGGPPG- 263
            G             +  +  PG SP ++   A G+     L   P  PGR G  G PG 
Sbjct: 657 PGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGP 716

Query: 264 ------GGIPACSIGPGLARLAALGGLPSILESSRLLPSPRSS 300
                  G P     PG        GLP  +      P P+ S
Sbjct: 717 AGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGD----PGPKGS 755



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/203 (28%), Positives = 74/203 (36%), Gaps = 53/203 (26%)

Query: 67   LLASRGITGCVNALGHRGSPEAVRGPGR--GRGPPNKAGRAAGSPTRVQRRPRPLRPSRA 124
            ++   G+ G   ++GH G P  +  PG    +GPP                      SR 
Sbjct: 1016 MMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPG---------------------SRG 1054

Query: 125  APRLRGEEPSLLRPQLSRRPRALRRSTRVP--AAGKGGDR--RAPVFPTLVPLHHGPPGA 180
             P +RG +               RR  R P   AG+ G R  + P  P   P   G PG 
Sbjct: 1055 PPGMRGAKG--------------RRGPRGPDGPAGEQGSRGLKGPPGPQGRP---GRPGQ 1097

Query: 181  SGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG 240
             GV  ER          +RG  FPGI G + GP    G+  +        P    GE G 
Sbjct: 1098 QGVAGERG------HLGSRG--FPGIPGPS-GPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148

Query: 241  ERPARALRRPRAPGRAGGGGPPG 263
            + P  A+  P  PG AG  G  G
Sbjct: 1149 KGPPGAVGEPGLPGEAGMKGDLG 1171



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 65/222 (29%), Positives = 78/222 (35%), Gaps = 37/222 (16%)

Query: 52   LIPRAAIRQSQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTR 111
            ++ R  +     PD L    G  G     G  G P  + GP   RG P  AG        
Sbjct: 1431 VVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPM-GPAGKRGNPGVAGLPGAQGPP 1489

Query: 112  VQRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLV 171
              +    L      P  RG E     P     P +          G+ GD     FP + 
Sbjct: 1490 GFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGS---------KGQPGDSGEMGFPGMA 1540

Query: 172  PLHHGPPGASGVGSERDRKFQLHQTPARGPP-FPGISGMTRGPVVLSGVNRQHRWPPGAS 230
             L  GP G  G     D  F+  Q P RGPP   G  G+  GP+ + G            
Sbjct: 1541 GLF-GPKGPPG-----DIGFKGIQGP-RGPPGLMGKEGIV-GPLGILG------------ 1580

Query: 231  PSRSLGEAG--GERPARALRRPRAP----GRAGGGGPPGGGI 266
            PS   G  G  G R    L+ PR P    GR G  GPPGG I
Sbjct: 1581 PSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPI 1622



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 71/283 (25%), Positives = 107/283 (37%), Gaps = 57/283 (20%)

Query: 22  RPAQTLQRTPRKHAASRGQAQ--------AAAAALTPSLIPRAAIRQSQAPDLLLA--SR 71
           +P +T    P +H A  G AQ        +A+ AL P ++P +    ++ P    A  S+
Sbjct: 299 KPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDP-MLPASVGGSTRTPRPAAAQPSQ 357

Query: 72  GITGCVNALGHRGSPEA-------VRGPGRGRGPPNKAGRAAGSPTRVQ----RRPRPLR 120
            IT           P A       ++ P   +     +   +  PT+ Q     RP P R
Sbjct: 358 KITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPAR 417

Query: 121 PSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTL------VPLH 174
            SR A     E+P    P + R P     STR P        + P+ PTL      +  H
Sbjct: 418 VSRPA-----EKPIQRNPGMPRPPPP---STR-PLPPTTSSSKKPI-PTLARTEAKITSH 467

Query: 175 HGPPGASGVGSERDRKF-QLHQTPARGPPFPGISGMTRGPVVL----SGVNRQHRWP--- 226
              P ++   + +   F  L  +PA   P PG +  TR P  +    SG +     P   
Sbjct: 468 ASKPASARTSTHKPPPFTALSSSPA---PTPGSTRSTRPPATMVPPTSGTSTPRTAPAVP 524

Query: 227 -PGASPSRSLGEAGGERPARALRR-------PRAPGRAGGGGP 261
            PG++P+ S    G E   +A  +       P  PG+A    P
Sbjct: 525 TPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVP 567



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 61/216 (28%), Positives = 84/216 (38%), Gaps = 30/216 (13%)

Query: 71   RGITGCVNALGHRGSP--EAVRGPGRGRGPPNKAG-RAAGSPTRVQRRPRPLRPSRAA-- 125
            +G+ G    LG RG P      GP   +G P + G +    P        P  P  A   
Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGE 1157

Query: 126  PRLRGEEPSL--LRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGV 183
            P L GE      L P  +   + L      P  G  GD   P+ P  +    G PG  G 
Sbjct: 1158 PGLPGEAGMKGDLGPLGTPGEQGLIGQRGEP--GLEGDS-GPMGPDGLKGDRGDPGPDGE 1214

Query: 184  GSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRS----LGEAG 239
              E+ ++  + +    GPP  G++G+ RGP   SG  +  +   GA  ++     LGE G
Sbjct: 1215 HGEKGQEGLMGEDGPPGPP--GVTGV-RGPEGKSG-KQGEKGRTGAKGAKGYQGQLGEMG 1270

Query: 240  -----------GERPARALRRPR-APGRAGGGGPPG 263
                       G + +R    P  APGR G  G PG
Sbjct: 1271 VPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPG 1306



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 59/216 (27%), Positives = 72/216 (33%), Gaps = 35/216 (16%)

Query: 70   SRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAA--GSPTRVQRRPRPLRPSRAAPR 127
            +RG+ G    LG  G  E   GP    G   + GR    G P     +  P  P R  P 
Sbjct: 932  ARGLPGPRGQLGPEGD-EGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPV 990

Query: 128  LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSER 187
              GE+  +    L   P  +         G+ GDR             GPPG  G     
Sbjct: 991  --GEQGFMGFIGLVGEPGIV---------GEKGDRGMM----------GPPGVPGPKGSM 1029

Query: 188  DRKFQLHQTPARGPPFPGISGMTRGPVVLSGVN--RQHRWPPGASPSRSLGEAGGERPAR 245
                        G P P     +RGP  + G    R  R P G  P+   G  G + P  
Sbjct: 1030 GHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDG--PAGEQGSRGLKGPPG 1087

Query: 246  ALRRPRAPGRAGGGGPPG-------GGIPACSIGPG 274
               RP  PG+ G  G  G        GIP  S  PG
Sbjct: 1088 PQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPG 1123



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 62/225 (27%), Positives = 81/225 (36%), Gaps = 38/225 (16%)

Query: 71   RGITGCVNALGHRGSPEAVRGPGRGRGPPN----KAGRAAGSPTRVQRRPRPLRPSRAAP 126
            +G TG   A G++G    +  PG   GPP     K  R +  PT    R      ++  P
Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPG-DPGPPGTPGPKGSRGSLGPTGAPGR----MGAQGEP 1305

Query: 127  RLRGEE--PSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASG-V 183
             L G +    ++ P     P+  +        G+ G    P          GPPG  G V
Sbjct: 1306 GLAGYDGHKGIVGPLGPPGPKGEKGEQ-----GEDGKAEGPP---------GPPGDRGPV 1351

Query: 184  GSERDRKFQLHQTPARGPPFPGISGMT--RGPVVLSGVNRQHRWPPGASPSRSLGEAGGE 241
            G   DR           P +PG  G+   RG     G    H  P G    +  G  G E
Sbjct: 1352 GDRGDRG------EPGDPGYPGQEGVQGLRGKPGQQG-QPGHPGPRGWPGPK--GSKGAE 1402

Query: 242  RPARALRRPRAPGRAGGGGPPGGGIPACSIG-PGLARLAALGGLP 285
             P     +  APGR G  G  G   P   +G  GL  +A   GLP
Sbjct: 1403 GPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLP 1447


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 63/222 (28%), Positives = 77/222 (34%), Gaps = 19/222 (8%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAA--GSPTRVQRRPRPLRPSR----AA 125
           G  G   A G RG+P   RGP    G P + G A   G+P     R     P R      
Sbjct: 474 GANGLPGAAGERGAP-GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG 532

Query: 126 PRLRGEEPSLLRPQLSRRPR---ALRRSTRVPAAGKGGDRRAPV---FPTL-----VPLH 174
           P +RG   S   P    +P    +   S R    G  G R  P    FP        P  
Sbjct: 533 PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGK 592

Query: 175 HGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRS 234
           +G  G  G    +    +  +T  +GPP P   G  +G     G       P    P   
Sbjct: 593 NGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE 652

Query: 235 LGEAGGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGPGL 275
            G+ G   P      P APG  G  G PG  G P  +  PGL
Sbjct: 653 NGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL 694



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 76/266 (28%), Positives = 93/266 (34%), Gaps = 56/266 (21%)

Query: 67   LLASRGITGCVNALGHRGSP--EAVRG----PGRG-----RGPPNKAGR-----AAGSPT 110
            +  +RG+ G     G RGSP  + V+G    PG       RGPP   G       AG P 
Sbjct: 952  ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011

Query: 111  RVQRRPRPLRPSR-AAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDR--RAPVF 167
            R         P R  +P  +G+      P     P        V  AGK GDR    P  
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG 1071

Query: 168  PTLVPLHHGPPGASGVGSERDRKFQLHQTPARG-------------PPFPGISGMT---- 210
            P   P   G  GA G    R  K +  +  A G             P  PG +G      
Sbjct: 1072 PAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131

Query: 211  -------RGPVVLSGVNRQ-----HRWPPGA-SPSRSLGEAGGERPARALRRPRAPGRAG 257
                   RGPV  SG   +     H  P G   P  + GE G E       +P  PG  G
Sbjct: 1132 SPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPG 1191

Query: 258  GGGPPGGGIPACSIGPGLARLAALGG 283
              GP  GG+       G A +A +GG
Sbjct: 1192 APGPCCGGV-------GAAAIAGIGG 1210



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 65/219 (29%), Positives = 79/219 (36%), Gaps = 16/219 (7%)

Query: 71  RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAA--GSP-TRVQRRPRPLRPSRAAPR 127
           RG  G   A G RG+ +  RG     GPP   G A   GSP  + +  P     S  AP 
Sbjct: 308 RGRPGLPGAAGARGN-DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366

Query: 128 LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHH--GPPGASGVGS 185
            RGE            P     +      G+ G    P  P L+      GP GA+G   
Sbjct: 367 QRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPG 426

Query: 186 ERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHR-WPPGASPSRSLGEAGGERP 243
            R    +  +  A+G P P G  G    P V        +   PG   +  L  A GER 
Sbjct: 427 LRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERG 486

Query: 244 ARALRRPRAP-------GRAGGGGPPGGGIPACSIG-PG 274
           A   R P  P       G AG  G PG   P  + G PG
Sbjct: 487 APGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 68/222 (30%), Positives = 76/222 (34%), Gaps = 33/222 (14%)

Query: 55  RAAIRQSQAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQR 114
           R   R    P  +    GI G     GHRG  +   G     G P   G   G P     
Sbjct: 238 RPGERGLPGPPGIKGPAGIPGFPGMKGHRGF-DGRNGEKGETGAPGLKGEN-GLPGE-NG 294

Query: 115 RPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLH 174
            P P+ P R AP  RG      RP L   P A        A G  G    P         
Sbjct: 295 APGPMGP-RGAPGERG------RPGL---PGAAGARGNDGARGSDGQPGPP--------- 335

Query: 175 HGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRS 234
            GPPG +G       K ++   PA  P   G  G    P        Q   PPG  P   
Sbjct: 336 -GPPGTAGFPGSPGAKGEVG--PAGSPGSNGAPGQRGEPGPQGHAGAQG--PPG--PPGI 388

Query: 235 LGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIG-PGL 275
            G  GG+        P APG  G  GPPG   PA + G PGL
Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARGPPG---PAGANGAPGL 427



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 88/320 (27%), Positives = 103/320 (32%), Gaps = 44/320 (13%)

Query: 9   APGLGGSK----KTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAP 64
           APG  G K      GE+ P         +  A     +    A  P   P AA      P
Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA----GTP 722

Query: 65  DL--LLASRGITGCVNALGHRGSP-----EAVRGPGRGRGPPNKAGRA--AGSPTRVQRR 115
            L  +   RG  G     G +G P     + V G    RGP    G    AG P      
Sbjct: 723 GLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEG 782

Query: 116 PRPLRPSRAAPR-LRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP--------- 165
             P  P  A PR   GE      P  +  P A  ++      G  G+R AP         
Sbjct: 783 GAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE---PGGKGERGAPGEKGEGGPP 839

Query: 166 --VFPTLVPLHHGPPGASGVGSERDRKFQLHQTP---ARGPPFPGISGMTRGPVVLSGVN 220
               P       GPPG  GV  ER             ARG P P  S    GP   SG  
Sbjct: 840 GVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSP 899

Query: 221 RQHRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAA 280
            +   P  A  + + G  G   P     +P   G  G  GPPG   P    G   AR   
Sbjct: 900 GKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR--G 957

Query: 281 LGGLPSILESSRLLPSPRSS 300
           L G P        +P PR S
Sbjct: 958 LAGPPG-------MPGPRGS 970



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 36/102 (35%), Positives = 41/102 (40%), Gaps = 37/102 (36%)

Query: 176 GPPGASG-VGSERDRKFQLHQTPARGPPF-PGISGMTRGPVVLSGVNRQHRWPPGA---- 229
           GPPG SG  GS     +Q       GPP  PG +G +  P            PPGA    
Sbjct: 183 GPPGTSGHPGSPGSPGYQ-------GPPGEPGQAGPSGPP-----------GPPGAIGPS 224

Query: 230 SPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG----GGIP 267
            P+   GE+G         RP  PG  G  GPPG     GIP
Sbjct: 225 GPAGKDGESG---------RPGRPGERGLPGPPGIKGPAGIP 257



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 46/154 (29%), Positives = 52/154 (33%), Gaps = 18/154 (11%)

Query: 31   PRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAPDLLLASRGITGCVNALGHRGSPEAVR 90
            P   +  RG++  A  A  P           Q P       G  G     GHRG P    
Sbjct: 1057 PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPG 1116

Query: 91   GPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE--EPSLLRPQLSRRPRALR 148
             PG   GP  + G A GSP     R  P+ PS   P   G    P  + P   R  R  R
Sbjct: 1117 APG-SPGPAGQQG-AIGSPGPAGPR-GPVGPS-GPPGKDGTSGHPGPIGPPGPRGNRGER 1172

Query: 149  RSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASG 182
             S   P  G  G    P          GPPGA G
Sbjct: 1173 GSEGSP--GHPGQPGPP----------GPPGAPG 1194



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 29/74 (39%), Positives = 32/74 (43%), Gaps = 12/74 (16%)

Query: 226 PPGASPSR-SLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGP-GLARLAALGG 283
           PPG S    S G  G + P      P  PG+AG  GPPG   P  +IGP G A      G
Sbjct: 184 PPGTSGHPGSPGSPGYQGP------PGEPGQAGPSGPPG---PPGAIGPSGPAGKDGESG 234

Query: 284 LPSILESSRLLPSP 297
            P      R LP P
Sbjct: 235 RPG-RPGERGLPGP 247


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 70/227 (30%), Positives = 82/227 (36%), Gaps = 28/227 (12%)

Query: 71  RGITGCVNALGHRGSP-----EAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAA 125
           RG  G    LG RG P        +GP    GPP   G +AG P R   R  P     A 
Sbjct: 327 RGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPG-SAGLPGR---RGPPGPKGEAG 382

Query: 126 PRLRGEEPSLLRPQLSRRPRALRRSTRVPAA----GKGGDRRAPVFPTLVPLHHGPPGAS 181
           P   G  P +   +  + P  L     VP      G  G    P  P   P   G PG  
Sbjct: 383 P---GGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP-GPTGPKGEPGFTGRPGGP 438

Query: 182 GVGSERDRKFQLH---QTPARGPP-FPGISGMTR--GPVVLSGVNRQHRWPPGASPSRSL 235
           GV     +K  L    Q   RGP   PG+ G     GP  L G+  +   P      R+ 
Sbjct: 439 GVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRA- 497

Query: 236 GEAGGERPARALRRPRAPGRAGGGGPPG----GGIPACSIGPGLARL 278
           GE G   P      P +PG  G  GPPG     G P      G+A L
Sbjct: 498 GEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGL 544



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 58/210 (27%), Positives = 74/210 (35%), Gaps = 36/210 (17%)

Query: 97  GPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE-----------EPSLLRPQLSRRPR 145
           GPP + G+       +   P  L+     P   G            +P + +P L  +P 
Sbjct: 53  GPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPG 112

Query: 146 ALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPP-FP 204
                   PA   G  R     P  +P   GPPG  G+  E   +         GPP  P
Sbjct: 113 --------PAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLP 164

Query: 205 GISGMT----------RGPVVLSGVNRQHRWPPGASPSRSL-GEAGGERPARALRRPRAP 253
           G SG+T           GP    G     +  PG    R L G+ G  +P      P AP
Sbjct: 165 GPSGITIPGKPGAQGVPGPPGFQG-EPGPQGEPGPPGDRGLKGDNGVGQPGL----PGAP 219

Query: 254 GRAGGGGPPGGGIPACSIGPGLARLAALGG 283
           G+ G  GPPG   PA    PGL  L    G
Sbjct: 220 GQGGAPGPPGLPGPAGLGKPGLDGLPGAPG 249



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 61/212 (28%), Positives = 76/212 (35%), Gaps = 34/212 (16%)

Query: 64  PDLLLASRGITGCVNALGHRGSPEAVRGPGR-GRGPPNKAGRA--AGSP--TRVQRRPRP 118
           P L +  +G  G     G RG P     PG+ G G P   G+   AG P  +R+ +   P
Sbjct: 69  PLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPP 128

Query: 119 LRPSRAAPR----LRGEEPSLLRPQLSRRPRA---LRRSTRVPAAGKGGDRRAPVFPTLV 171
             P +  P     LRGE P +   Q  R P     L   + +   GK G +  P  P   
Sbjct: 129 GLPGKVGPPGQPGLRGE-PGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQ 187

Query: 172 PLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASP 231
               GP G  G   +R  K          P  PG  G    P            PPG   
Sbjct: 188 G-EPGPQGEPGPPGDRGLK---GDNGVGQPGLPGAPGQGGAP-----------GPPGLPG 232

Query: 232 SRSLGEAGGERPARALRRPRAPGRAGGGGPPG 263
              LG+ G +        P APG  G  GPPG
Sbjct: 233 PAGLGKPGLDG------LPGAPGDKGESGPPG 258



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 59/214 (27%), Positives = 79/214 (36%), Gaps = 24/214 (11%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE-----EPSL 135
           G RG P  +RG    RGPP   G    S   +  +P   +     P  +GE     EP  
Sbjct: 141 GLRGEP-GIRGDQGLRGPPGPPGLPGPSGITIPGKPGA-QGVPGPPGFQGEPGPQGEPGP 198

Query: 136 LRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQ 195
              +  +    + +     A G+GG    P  P   P   G PG  G+      K +   
Sbjct: 199 PGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPG--PAGLGKPGLDGLPGAPGDKGESGP 256

Query: 196 TPARGPPF-PGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPRAPG 254
               GP   PG  G  +GP  + GV       PGA+     G  G + P+ A   P   G
Sbjct: 257 PGVPGPRGEPGAVG-PKGPPGVDGVG-----VPGAA-----GLPGPQGPSGAKGEPGTRG 305

Query: 255 RAGGGGPPGGGIPACSIGPGLARLAALGGLPSIL 288
             G  GP G G+P     PG        G+P +L
Sbjct: 306 PPGLIGPTGYGMPGL---PGPKGDRGPAGVPGLL 336


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 64/220 (29%), Positives = 78/220 (35%), Gaps = 42/220 (19%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE 131
            G  G     G  G+P  V GP   +G P    R    P   Q  P P  PS    +L   
Sbjct: 829  GKPGDTGPQGFPGTPGDV-GPKGDKGDPGVGERGPPGP---QGPPGPPGPSFRHDKLTFI 884

Query: 132  EPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKF 191
            +                    +  +G GGD  A   P   P   GPPG  G+  E  R F
Sbjct: 885  D--------------------MEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR-F 923

Query: 192  QLHQTPARGPP-FPGISGMTRGPVVLSGVNRQ-----HRWPPGASPSR-SLGEAGGER-- 242
             ++ +   GP   PG+ G   GP    G+           PPG +  + SLGEAG     
Sbjct: 924  GVNSSDVPGPAGLPGVPGR-EGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHK 982

Query: 243  -------PARALRRPRAPGRAGGGGPPGGGIPACSIGPGL 275
                   PA A       G  G  GPPG   P    GPGL
Sbjct: 983  GSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGL 1022



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 65/250 (26%), Positives = 81/250 (32%), Gaps = 50/250 (20%)

Query: 68   LASRGITGCVNALGHRGSPEAVRGPGRG---------------RGPPNKAGRAAGSPTRV 112
            L S+G  G     G +G P ++  P  G               RGPP   GR  G    +
Sbjct: 1162 LGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGR-PGYKGEI 1220

Query: 113  QRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVP 172
                RP RP      L+GE+       L    R +      P  G  G    PV+ + V 
Sbjct: 1221 GFPGRPGRPGMNG--LKGEKGEPGDASLGFGMRGMPGPPGPP--GPPGPPGTPVYDSNVF 1276

Query: 173  LHHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWPPGASP 231
                 PG  G+               +GPP P G  G    P            PPG  P
Sbjct: 1277 AESSRPGPPGLPGN------------QGPPGPKGAKGEVGPP-----------GPPGQFP 1313

Query: 232  SRSL---GEAGGERPARALRRPRAP-GRAGGGGPPGGGIPACSIGPGLARLAALGGLPSI 287
               L    E  GE+  R     +   G  GGGG  G  +P     PG      + G    
Sbjct: 1314 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG- 1372

Query: 288  LESSRLLPSP 297
             ES R  P P
Sbjct: 1373 -ESIRGQPGP 1381



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 18/140 (12%)

Query: 156  AGKGGDRRAP----VFPTLVPLHHGPPGASGV-GSERDRKFQLHQTPARGPPFPGISGMT 210
            AG+ G+R  P     F + +P   GPPG  G  G    +   +   P  GPP P      
Sbjct: 1333 AGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQP--GPPGP------ 1384

Query: 211  RGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPAR-ALRRPRAPGRAGGGGPPGGGIPAC 269
            +GP  +    RQ   PPG  P    G      P R  +  P  PG  G  GPPG    + 
Sbjct: 1385 QGPPGIGYEGRQG--PPG--PPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASS 1440

Query: 270  SIGPGLARLAALGGLPSILE 289
             +     R A LG +  + E
Sbjct: 1441 GVRLWATRQAMLGQVHEVPE 1460



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 42/142 (29%), Positives = 49/142 (34%), Gaps = 16/142 (11%)

Query: 126  PRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGS 185
            P L G E  +  PQ  +  R  R     P     G    P  P       GPPG     S
Sbjct: 1080 PGLPGRE-GIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPP-------GPPGPVVYVS 1131

Query: 186  ERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG----E 241
            E+D        P   P F G  G   GP    G ++  R  PG  P    GE G     +
Sbjct: 1132 EQDGSVLSVPGPEGRPGFAGFPG-PAGPKGNLG-SKGERGSPG--PKGEKGEPGSIFSPD 1187

Query: 242  RPARALRRPRAPGRAGGGGPPG 263
              A    +  A G  G  GPPG
Sbjct: 1188 GGALGPAQKGAKGEPGFRGPPG 1209


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 64/220 (29%), Positives = 78/220 (35%), Gaps = 42/220 (19%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE 131
           G  G     G  G+P  V GP   +G P    R    P   Q  P P  PS    +L   
Sbjct: 414 GKPGDTGPQGFPGTPGDV-GPKGDKGDPGVGERGPPGP---QGPPGPPGPSFRHDKLTFI 469

Query: 132 EPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKF 191
           +                    +  +G GGD  A   P   P   GPPG  G+  E  R F
Sbjct: 470 D--------------------MEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR-F 508

Query: 192 QLHQTPARGPP-FPGISGMTRGPVVLSGVNRQ-----HRWPPGASPSR-SLGEAGGER-- 242
            ++ +   GP   PG+ G   GP    G+           PPG +  + SLGEAG     
Sbjct: 509 GVNSSDVPGPAGLPGVPGR-EGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHK 567

Query: 243 -------PARALRRPRAPGRAGGGGPPGGGIPACSIGPGL 275
                  PA A       G  G  GPPG   P    GPGL
Sbjct: 568 GSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGL 607



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 65/250 (26%), Positives = 81/250 (32%), Gaps = 50/250 (20%)

Query: 68  LASRGITGCVNALGHRGSPEAVRGPGRG---------------RGPPNKAGRAAGSPTRV 112
           L S+G  G     G +G P ++  P  G               RGPP   GR  G    +
Sbjct: 747 LGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGR-PGYKGEI 805

Query: 113 QRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVP 172
               RP RP      L+GE+       L    R +      P  G  G    PV+ + V 
Sbjct: 806 GFPGRPGRPGMNG--LKGEKGEPGDASLGFGMRGMPGPPGPP--GPPGPPGTPVYDSNVF 861

Query: 173 LHHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWPPGASP 231
                PG  G+               +GPP P G  G    P            PPG  P
Sbjct: 862 AESSRPGPPGLPGN------------QGPPGPKGAKGEVGPP-----------GPPGQFP 898

Query: 232 SRSL---GEAGGERPARALRRPRAP-GRAGGGGPPGGGIPACSIGPGLARLAALGGLPSI 287
              L    E  GE+  R     +   G  GGGG  G  +P     PG      + G    
Sbjct: 899 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG- 957

Query: 288 LESSRLLPSP 297
            ES R  P P
Sbjct: 958 -ESIRGQPGP 966



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 18/140 (12%)

Query: 156  AGKGGDRRAP----VFPTLVPLHHGPPGASGV-GSERDRKFQLHQTPARGPPFPGISGMT 210
            AG+ G+R  P     F + +P   GPPG  G  G    +   +   P  GPP P      
Sbjct: 918  AGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQP--GPPGP------ 969

Query: 211  RGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPAR-ALRRPRAPGRAGGGGPPGGGIPAC 269
            +GP  +    RQ   PPG  P    G      P R  +  P  PG  G  GPPG    + 
Sbjct: 970  QGPPGIGYEGRQG--PPG--PPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASS 1025

Query: 270  SIGPGLARLAALGGLPSILE 289
             +     R A LG +  + E
Sbjct: 1026 GVRLWATRQAMLGQVHEVPE 1045



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 42/142 (29%), Positives = 49/142 (34%), Gaps = 16/142 (11%)

Query: 126 PRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGS 185
           P L G E  +  PQ  +  R  R     P     G    P  P       GPPG     S
Sbjct: 665 PGLPGRE-GIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPP-------GPPGPVVYVS 716

Query: 186 ERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG----E 241
           E+D        P   P F G  G   GP    G ++  R  PG  P    GE G     +
Sbjct: 717 EQDGSVLSVPGPEGRPGFAGFPG-PAGPKGNLG-SKGERGSPG--PKGEKGEPGSIFSPD 772

Query: 242 RPARALRRPRAPGRAGGGGPPG 263
             A    +  A G  G  GPPG
Sbjct: 773 GGALGPAQKGAKGEPGFRGPPG 794


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1516

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 64/220 (29%), Positives = 78/220 (35%), Gaps = 42/220 (19%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE 131
           G  G     G  G+P  V GP   +G P    R    P   Q  P P  PS    +L   
Sbjct: 594 GKPGDTGPQGFPGTPGDV-GPKGDKGDPGVGERGPPGP---QGPPGPPGPSFRHDKLTFI 649

Query: 132 EPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKF 191
           +                    +  +G GGD  A   P   P   GPPG  G+  E  R F
Sbjct: 650 D--------------------MEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGR-F 688

Query: 192 QLHQTPARGPP-FPGISGMTRGPVVLSGVNRQ-----HRWPPGASPSR-SLGEAGGER-- 242
            ++ +   GP   PG+ G   GP    G+           PPG +  + SLGEAG     
Sbjct: 689 GVNSSDVPGPAGLPGVPGR-EGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHK 747

Query: 243 -------PARALRRPRAPGRAGGGGPPGGGIPACSIGPGL 275
                  PA A       G  G  GPPG   P    GPGL
Sbjct: 748 GSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGL 787



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 65/250 (26%), Positives = 81/250 (32%), Gaps = 50/250 (20%)

Query: 68   LASRGITGCVNALGHRGSPEAVRGPGRG---------------RGPPNKAGRAAGSPTRV 112
            L S+G  G     G +G P ++  P  G               RGPP   GR  G    +
Sbjct: 927  LGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGR-PGYKGEI 985

Query: 113  QRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVP 172
                RP RP      L+GE+       L    R +      P  G  G    PV+ + V 
Sbjct: 986  GFPGRPGRPGMNG--LKGEKGEPGDASLGFGMRGMPGPPGPP--GPPGPPGTPVYDSNVF 1041

Query: 173  LHHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWPPGASP 231
                 PG  G+               +GPP P G  G    P            PPG  P
Sbjct: 1042 AESSRPGPPGLPGN------------QGPPGPKGAKGEVGPP-----------GPPGQFP 1078

Query: 232  SRSL---GEAGGERPARALRRPRAP-GRAGGGGPPGGGIPACSIGPGLARLAALGGLPSI 287
               L    E  GE+  R     +   G  GGGG  G  +P     PG      + G    
Sbjct: 1079 FDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKG- 1137

Query: 288  LESSRLLPSP 297
             ES R  P P
Sbjct: 1138 -ESIRGQPGP 1146



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 18/140 (12%)

Query: 156  AGKGGDRRAP----VFPTLVPLHHGPPGASGV-GSERDRKFQLHQTPARGPPFPGISGMT 210
            AG+ G+R  P     F + +P   GPPG  G  G    +   +   P  GPP P      
Sbjct: 1098 AGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQP--GPPGP------ 1149

Query: 211  RGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPAR-ALRRPRAPGRAGGGGPPGGGIPAC 269
            +GP  +    RQ   PPG  P    G      P R  +  P  PG  G  GPPG    + 
Sbjct: 1150 QGPPGIGYEGRQG--PPG--PPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASS 1205

Query: 270  SIGPGLARLAALGGLPSILE 289
             +     R A LG +  + E
Sbjct: 1206 GVRLWATRQAMLGQVHEVPE 1225



 Score = 28.5 bits (62), Expect = 7.7
 Identities = 42/142 (29%), Positives = 49/142 (34%), Gaps = 16/142 (11%)

Query: 126 PRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGS 185
           P L G E  +  PQ  +  R  R     P     G    P  P       GPPG     S
Sbjct: 845 PGLPGRE-GIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPP-------GPPGPVVYVS 896

Query: 186 ERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGG----E 241
           E+D        P   P F G  G   GP    G ++  R  PG  P    GE G     +
Sbjct: 897 EQDGSVLSVPGPEGRPGFAGFPG-PAGPKGNLG-SKGERGSPG--PKGEKGEPGSIFSPD 952

Query: 242 RPARALRRPRAPGRAGGGGPPG 263
             A    +  A G  G  GPPG
Sbjct: 953 GGALGPAQKGAKGEPGFRGPPG 974


>gi|50511941 EMI domain containing 1 [Homo sapiens]
          Length = 443

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 53/193 (27%), Positives = 69/193 (35%), Gaps = 36/193 (18%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE 131
           G TG     G RG P  +RGP   +GPP   GRA    T  +R P    P    P     
Sbjct: 205 GPTGPKGDAGSRG-PMGMRGPPGPQGPPGSPGRAGAVGTPGERGP----PGPPGPPGPPG 259

Query: 132 EPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKF 191
            P+ + P  +R  +                             HG P  S   +E +  +
Sbjct: 260 PPAPVGPPHARISQ-----------------------------HGDPLLSNTFTETNNHW 290

Query: 192 QLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALR-RP 250
               T   GPP P       GP  + G +  H  PPG +  + +    GE+  R LR  P
Sbjct: 291 PQGPTGPPGPPGPMGPPGPPGPTGVPG-SPGHIGPPGPTGPKGISGHPGEKGERGLRGEP 349

Query: 251 RAPGRAGGGGPPG 263
              G AG  G PG
Sbjct: 350 GPQGSAGQRGEPG 362



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 35/108 (32%), Positives = 45/108 (41%), Gaps = 14/108 (12%)

Query: 176 GPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPG-ASPSRS 234
           GPP A G   +   + Q+      GP  P     +RGP+ + G       PPG   P  S
Sbjct: 181 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRG-------PPGPQGPPGS 233

Query: 235 LGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALG 282
            G AG      A+  P   G  G  GPPG   P   +GP  AR++  G
Sbjct: 234 PGRAG------AVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHG 275


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/229 (27%), Positives = 77/229 (33%), Gaps = 46/229 (20%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGR-----AAGSPTRVQRRPRPLRPSRAAP 126
           G+ G     G RG PE  +G     GPP   G      A G+      +     P  + P
Sbjct: 384 GMKGEAGPTGARG-PEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGP 442

Query: 127 RLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVF-----PTLVPLHHGPPGAS 181
                 P    PQ S  P+ +R        G+ GD   P F     P   P  HG  G  
Sbjct: 443 PGSAGPPGSPGPQGSTGPQGIR--------GQPGDPGVPGFKGEAGPKGEPGPHGIQGPI 494

Query: 182 GVGSERDRKFQLHQTPARGPP-------------FPGISGMT--------RGPVVLSGVN 220
           G   E  ++         GPP             FPG  G+         RGPV  SG  
Sbjct: 495 GPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPK 554

Query: 221 RQHRWP-----PGASPSRSL-GEAGGERPARALRRPRAPGRAGGGGPPG 263
                P     PG   +R L G  G + P   L    APG  G  GPPG
Sbjct: 555 GSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPG 603



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 67/206 (32%), Positives = 77/206 (37%), Gaps = 40/206 (19%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE 131
           G  G     GHRG  + + GP    G P   G A   PT       PL P R  P  RG 
Sbjct: 291 GAPGLPGLKGHRGH-KGLEGPKGEVGAPGSKGEAG--PTGPMGAMGPLGP-RGMPGERGR 346

Query: 132 EPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFP-TLVPLHHGPPGASGVGSERDRK 190
               L PQ               A G+ G    P  P  + PL  G PG+SG       K
Sbjct: 347 ----LGPQ--------------GAPGQRGAHGMPGKPGPMGPL--GIPGSSGFPGNPGMK 386

Query: 191 FQLHQTPARGPPFP-GISGMTR--GPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARAL 247
            +   T ARGP  P G  G T   GPV   G+       PGA  +   G  G + P  + 
Sbjct: 387 GEAGPTGARGPEGPQGQRGETGPPGPVGSPGL-------PGAIGTD--GTPGAKGPTGS- 436

Query: 248 RRPRAPGRAGGGGPPGGGIPACSIGP 273
             P   G  G  GPPG   P  S GP
Sbjct: 437 --PGTSGPPGSAGPPGSPGPQGSTGP 460



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 65/216 (30%), Positives = 75/216 (34%), Gaps = 40/216 (18%)

Query: 71  RGITGCVNALGHRGS-----PEAVRGPGRGRGPPNKAGRAA-GSPTRVQRRPRP---LRP 121
           RGI G     G RG       E   G    RG P   G      PT  +  P P   + P
Sbjct: 767 RGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGP 826

Query: 122 --SRAAPRLRGEEP-----SLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLV--P 172
             SR  P  RGE           PQ       ++     P  G+ GD  +P    L   P
Sbjct: 827 PGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEP--GQKGDAGSPGPQGLAGSP 884

Query: 173 LHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGA-SP 231
             HGP G  G+   R       Q P     FPG +G    P            P GA  P
Sbjct: 885 GPHGPNGVPGLKGGRGT-----QGPPGATGFPGSAGRVGPP-----------GPAGAPGP 928

Query: 232 SRSLGEAGGERPARALRRPRAPGRAGG---GGPPGG 264
           +  LGE G E P      P + GR G     GPPGG
Sbjct: 929 AGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGG 964



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 59/204 (28%), Positives = 69/204 (33%), Gaps = 48/204 (23%)

Query: 72   GITGCVNALGHRGSPEAVRGPGR-GR-GPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLR 129
            G+ G     G +G P A   PG  GR GPP  AG  A  P      P    P    P LR
Sbjct: 891  GVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG--APGPAGPLGEPGKEGP----PGLR 944

Query: 130  GEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDR 189
            G+  S                      G+ GDR  P  P   P   G PG  G       
Sbjct: 945  GDPGS---------------------HGRVGDR-GPAGPPGGPGDKGDPGEDG------- 975

Query: 190  KFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRR 249
                 Q    GPP P  +   RG V + G   +   P    P+ + G+ G   P  A   
Sbjct: 976  -----QPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVG---PTGATGD 1027

Query: 250  PRAPGRAGGGGPPGGGIPACSIGP 273
               PG     GPPG   P    GP
Sbjct: 1028 KGPPGPV---GPPGSNGPVGEPGP 1048



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 61/227 (26%), Positives = 78/227 (34%), Gaps = 28/227 (12%)

Query: 72  GITGCVNALGHRGSPEAVR--GPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLR 129
           G  G   ++G RG P ++   GP    G P K G A  +    QR   P +     P   
Sbjct: 597 GRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGA-PGKDGEVGPSGP 655

Query: 130 GEEPSLLRPQLSRRPRALRRSTRVPA-------AGKGGDRRAPVFPTLV----------- 171
              P L   +  + P        +P         GK GD+  P  P  V           
Sbjct: 656 VGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGN 715

Query: 172 PLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGV--NRQHRWPPGA 229
           P   G PG +G+  E+           +G P P  +    GP  L G+   R     PG 
Sbjct: 716 PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGP 775

Query: 230 SPSRS-LGEAGGERPARALRRPRAPGRAGGGGPPGGGIPACSIG-PG 274
              R  +GE G E  A       A G  G  GPPG   P    G PG
Sbjct: 776 KGDRGGIGEKGAEGTAG---NDGARGLPGPLGPPGPAGPTGEKGEPG 819



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 65/227 (28%), Positives = 75/227 (33%), Gaps = 37/227 (16%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGE 131
            G  G V   G RG P     PG  +G P   G   G+P    +R  P       P  R  
Sbjct: 1059 GRDGAVGERGDRGDPGPAGLPG-SQGAPGTPG-PVGAPGDAGQRGDPGSRGPIGPPGRAG 1116

Query: 132  EPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKF 191
            +  L  PQ  R  +           G  GDR          L  G PG  G   E+    
Sbjct: 1117 KRGLPGPQGPRGDKGDH--------GDRGDRGQKGHRGFTGLQ-GLPGPPGPNGEQGSAG 1167

Query: 192  QLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRP 250
                   RGPP P G SG    P  L  +      PPG   S  +GEAG E         
Sbjct: 1168 IPGPFGPRGPPGPVGPSGKEGNPGPLGPIG-----PPGVRGS--VGEAGPE--------- 1211

Query: 251  RAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESSRLLPSP 297
                     GPPG   P    GP     AALG +    + S   P P
Sbjct: 1212 ---------GPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLP 1249



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 63/234 (26%), Positives = 77/234 (32%), Gaps = 27/234 (11%)

Query: 62  QAPDLLLASRGITGCVNALGHRGSPEAV-----RGPGRGRGPPNKAGRAA-----GSPTR 111
           + P  L   +G  G     G  G P  +     RGP    GPP K G        G+P  
Sbjct: 221 RGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGP---EGPPGKPGEDGEPGRNGNPGE 277

Query: 112 VQRRPRP-LRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRA--PVFP 168
           V     P  R    AP L G +       L      +        AG  G   A  P+ P
Sbjct: 278 VGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGP 337

Query: 169 TLVPLHHGPPGASGVGSERDRKFQLHQTPARGP-PFPGISGMTRGPVVLSGVNRQHRWPP 227
             +P   G  G  G   +R       +    GP   PG SG    P +     +    P 
Sbjct: 338 RGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGM-----KGEAGPT 392

Query: 228 GA-SPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGG----GIPACSIGPGLA 276
           GA  P    G+ G   P   +  P  PG  G  G PG     G P  S  PG A
Sbjct: 393 GARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSA 446



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 61/212 (28%), Positives = 74/212 (34%), Gaps = 26/212 (12%)

Query: 64  PDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSR 123
           P  L   RG  G     G +G P     PG G G P   G   G P  V   P   R  R
Sbjct: 658 PPGLAGERGEQGPPGPTGFQGLPGPPGPPGEG-GKPGDQG-VPGDPGAV--GPLGPRGER 713

Query: 124 AAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGD-RRAPVFPTLVPLHHGPPGASG 182
             P  RGE      P ++  P       +  A G G D  +    P+  P   GPPG  G
Sbjct: 714 GNPGERGE------PGITGLP-----GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQG 762

Query: 183 VGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAG--G 240
           +  ER     +  TP       GI    +G    +G +     P    P    G  G  G
Sbjct: 763 MPGERG----IAGTPGPKGDRGGIG--EKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKG 816

Query: 241 ERPARALRRPRAPGRAGGGGPPGGGIPACSIG 272
           E   R L  P  PG  G  G  G   P  ++G
Sbjct: 817 EPGPRGLVGP--PGSRGNPGSRGENGPTGAVG 846



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 61/218 (27%), Positives = 71/218 (32%), Gaps = 43/218 (19%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQL 140
           G +G P  V      RG P  AG       R +R P+  RP    P+    EP       
Sbjct: 113 GQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKG-RPGPRGPQGIDGEP------- 164

Query: 141 SRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSER----DRKFQLHQT 196
                           G  G   AP  P   P H GP G S   S +    D K  L   
Sbjct: 165 ----------------GVPGQPGAP-GPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQ 207

Query: 197 PARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARAL--RRPRA-P 253
               P   G  G  RGP  L G         GA P+   GE G   P   +  R P   P
Sbjct: 208 VGLMPGSVGPVG-PRGPQGLQGQQ------GGAGPTGPPGEPGDPGPMGPIGSRGPEGPP 260

Query: 254 GRAGGGGPPGGGIPACSIG----PGLARLAALGGLPSI 287
           G+ G  G PG       +G    PG        GLP +
Sbjct: 261 GKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL 298



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 63/220 (28%), Positives = 78/220 (35%), Gaps = 37/220 (16%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP-SRAAPRLRG 130
           G+ G     G  G+P   +G   G G     G A     R    P PL P   A P    
Sbjct: 759 GLQGMPGERGIAGTP-GPKGDRGGIGEKGAEGTAGNDGAR--GLPGPLGPPGPAGPTGEK 815

Query: 131 EEPS---LLRPQLSR-RPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
            EP    L+ P  SR  P +   +    A G  G +             GP G  GV  E
Sbjct: 816 GEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQ-------------GPDGQPGVKGE 862

Query: 187 RDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARA 246
                Q     + GP   G++G + GP   +GV       PG    R     G + P  A
Sbjct: 863 PGEPGQKGDAGSPGPQ--GLAG-SPGPHGPNGV-------PGLKGGR-----GTQGPPGA 907

Query: 247 LRRPRAPGRAGGGGPPGGGIPACSIG-PGLARLAALGGLP 285
              P + GR G  GP G   PA  +G PG      L G P
Sbjct: 908 TGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDP 947



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 29/96 (30%), Positives = 33/96 (34%), Gaps = 16/96 (16%)

Query: 172 PLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASP 231
           P+    PG       R RK Q  + P   P   GI G   GP            PPG+  
Sbjct: 94  PVCSQTPGGGNTNFGRGRKGQKGE-PGLVPVVTGIRGRP-GPA----------GPPGSQG 141

Query: 232 SRS----LGEAGGERPARALRRPRAPGRAGGGGPPG 263
            R      G  G   P      P  PG+ G  GPPG
Sbjct: 142 PRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPG 177


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 79/277 (28%), Positives = 98/277 (35%), Gaps = 42/277 (15%)

Query: 4   KPRSPA--PGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQS 61
           +PR  A  PG        +  PA    RT +    + GQAQA         +P A  RQ+
Sbjct: 19  QPRQVASSPGHPSQPPLEDNTPAT---RTTKGAREAGGQAQAME-------LPEAQPRQA 68

Query: 62  QAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP 121
           +  +L   S       +  G RGSP+   G    + P   AGRA GSP   QR    +  
Sbjct: 69  RDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPP--QRYILGIAS 126

Query: 122 SRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGAS 181
           SR  P L  E P    PQL         + + P  G      AP+ P L P     P A 
Sbjct: 127 SRTKPTL-DETPE--NPQLEAAQLPEVDTPQGPGTG------APLRPGL-PRTEAQPAAE 176

Query: 182 GVGSER--------------DRKFQLHQTPARGPP-FPGISGMTRGPVVLSGVNRQHRWP 226
            +G  R                     + PA GPP   G S +  G       +    WP
Sbjct: 177 ELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWP 236

Query: 227 PGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG 263
           P A  S   G   G  PA     P   G   GG P G
Sbjct: 237 PAAENSFP-GANFGVPPAEP--EPIPKGSRPGGSPRG 270



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 62/251 (24%), Positives = 85/251 (33%), Gaps = 44/251 (17%)

Query: 4    KPRSPAPGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQA 63
            +P    PG  G +  GEKR    L + PR+    +               PR A RQ   
Sbjct: 1075 QPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQK---------------PRKAARQEAG 1119

Query: 64   PDLLLASRGITGCVNALGHRGSPEAVRGPGRG--------RGPPNKAGRAAGSPTRVQRR 115
             D   A+    G  +  G   SP+A RGP R          G P  A R + +P      
Sbjct: 1120 GDGAPANPEEPG-GSRPGPGRSPQA-RGPSRSLETGAAAREGGPKCADRPSVAP------ 1171

Query: 116  PRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRST----------RVPAAGKGGDRRAP 165
              PL+            PSL  PQ ++ P     S           R P A   G+  A 
Sbjct: 1172 KDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGAS 1231

Query: 166  VFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGP-VVLSGVNRQHR 224
              P L+     PP     G+ +      +  P    P PG+  +  GP    + V+   +
Sbjct: 1232 --PGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSK 1289

Query: 225  WPPGASPSRSL 235
             PP   P   L
Sbjct: 1290 DPPARQPGEFL 1300



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 50/219 (22%), Positives = 76/219 (34%), Gaps = 33/219 (15%)

Query: 7    SPAPGLGG--SKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAP 64
            SP PG+G       G + P     + P   A   G+  A  A  + +  P+ ++  S+  
Sbjct: 1265 SPTPGVGSLLGGPGGTQAPVSHNSKDPP--ARQPGEFLAPVANPSSTACPKPSVLSSKIS 1322

Query: 65   DLLLASRGITGCVNALGHR---GSPEAVRGPGRGRGPPNK---AGRAAGSPTRVQRRPRP 118
                      GC  A  +R   G P A +GP     P ++     +        +  P+P
Sbjct: 1323 SF--------GCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKP 1374

Query: 119  LRPSRAAPRLR-------GEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLV 171
               +R AP          GE+   L PQL R P     +    AA       + +FP L 
Sbjct: 1375 --SARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLP 1432

Query: 172  PLHHGPPGASGVGSERDRKFQL------HQTPARGPPFP 204
                 PP    + + RD            +T    PP+P
Sbjct: 1433 VDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYP 1471


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 68/237 (28%), Positives = 89/237 (37%), Gaps = 38/237 (16%)

Query: 67   LLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAP 126
            L+   G+ G +  +G  G P+ V GP    G P + G + G P +   +  P   S   P
Sbjct: 1019 LIGPPGLKGTIGDMGFPG-PQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLP 1076

Query: 127  RLRGEEPSLLRPQLSRRPRALRRSTRVPAA----GKGGDRRAPVFPTLVPLHHGPPGASG 182
             L G +     P     P  ++ S   P      G  G +  P  P   P   GPPG  G
Sbjct: 1077 GLPGPKGEPGLPGYPGNP-GIKGSVGDPGLPGLPGTPGAKGQPGLPGF-PGTPGPPGPKG 1134

Query: 183  VGSERDRKFQLHQTPARGPPF-PGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGE 241
            +                GPP  PG+ G   GPV   G    H   PG  P    G+ G +
Sbjct: 1135 IS---------------GPPGNPGLPGEP-GPVGGGG----HPGQPG--PPGEKGKPGQD 1172

Query: 242  RPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESSRLLPSPR 298
                    P   G+ G  G PG G P     PGL+     GGLP I   +  LP P+
Sbjct: 1173 GI------PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGI-PGNPGLPGPK 1222



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 64/210 (30%), Positives = 71/210 (33%), Gaps = 35/210 (16%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQL 140
           G RG P    GP   RGPP   G   G     Q  P      R  P   GE      P L
Sbjct: 264 GDRGPP----GPPGIRGPPGPPGGEKGEKGE-QGEPG----KRGKPGKDGENGQPGIPGL 314

Query: 141 SRRPRALRRSTRVPAAGKGGDRRAPVFPTLV------PLHHGPPGASGV----GSERDRK 190
              P       R    G+ GD   P  P LV       +  G  G  G+    G + +R 
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 191 FQLHQTPARGPPFPGISGM-TRGPVVLSGVNRQH--RWPPGASPSRSLGEAGGERPARAL 247
           F   Q P   P  PG + M   GP    G   Q     PPG S     G  G        
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG-------- 426

Query: 248 RRPRAPGRAGGGGPPGGGIP----ACSIGP 273
            +P APG  G  GP G  IP     C  GP
Sbjct: 427 -QPGAPGLPGPPGPAGPHIPPSDEICEPGP 455



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 72/264 (27%), Positives = 85/264 (32%), Gaps = 68/264 (25%)

Query: 72  GITGCVNALGHRGSPE-AVRGPGRGRGPPNKAGR--AAGSPTRVQRRPRPLRPSRAAPRL 128
           G+ G   + G  G P   + GP   +G P   G   A G+P R+     P  P    P+ 
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK- 748

Query: 129 RGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP--------------------VFP 168
              EP    P     P          A G  GDR  P                    V P
Sbjct: 749 --GEPGFALPGPPGPPGLPGFKG---ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 169 TLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWP- 226
              P   GPPG  G+G              +GPP P GI G    P  L G+  +   P 
Sbjct: 804 NGQPGPMGPPGLPGIG-------------VQGPPGPPGIPGPIGQPG-LHGIPGEKGDPG 849

Query: 227 ------PGASPSR-SLGEAGGERPARALRRPRAPGRAGGGGPPGG--------------- 264
                 PG    R S G  G   P      P  PG+AG  G PG                
Sbjct: 850 PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 265 -GIPACSIGPGLARLAALGGLPSI 287
            GIP  S  PGL     L G P +
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGL 933



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 42/149 (28%), Positives = 54/149 (36%), Gaps = 34/149 (22%)

Query: 157 GKGGDRRAPVFPTL--VPLHHGPPGASGV-GSERDRKFQLHQTPARGPPFPGISGMTRGP 213
           G+ G   AP  P L   P   G PG  G  G      F+  + P   P  PG+ G   GP
Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI-GP 619

Query: 214 VVLSGVNRQHRWPPGASPSRSLGEAGGE----------------RPARALRRPRAPGRAG 257
           +           PPG  P   +GE G +                 P + + +P  PG  G
Sbjct: 620 M----------GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 258 GGGPPGG-GIPACSIGPGLARLAALGGLP 285
             G  G  G+P     PGL     L G+P
Sbjct: 670 NPGRDGDVGLPG---DPGLPGQPGLPGIP 695



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 56/206 (27%), Positives = 73/206 (35%), Gaps = 23/206 (11%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGR----GPPNKAGRAA--GSPTRVQRRPRPLRPSRAA 125
            GI G +   G  G P     PG       GPP + G     G+P  +     P  P +A 
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887

Query: 126  ----PRLRGEEPSLLRPQLSRRPRALRRSTRVPAA-GKGGDRRAPVFP--TLVPLHHGPP 178
                P  +GE   ++ P     P  +   + VP   G  G +  P  P  T      G P
Sbjct: 888  ASGFPGTKGEM-GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP 946

Query: 179  GASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSL-GE 237
            G  G     D      +     P  PGI G++ GP    G+       PG      L G+
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS-GPKGYQGL-------PGDPGQPGLSGQ 998

Query: 238  AGGERPARALRRPRAPGRAGGGGPPG 263
             G   P      P  PG+ G  GPPG
Sbjct: 999  PGLPGPPGPKGNPGLPGQPGLIGPPG 1024



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 67/246 (27%), Positives = 88/246 (35%), Gaps = 47/246 (19%)

Query: 72   GITGCVNALGHRGSP-EAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPR--L 128
            G  G     G  GSP  A+ GP    GP    GR    PT  Q  P P  P        +
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG--PTGFQGLPGPEGPPGLPGNGGI 1286

Query: 129  RGEEPSLLRPQL--------SRRPRALRRSTRVPAA----GKGGDRRAPVFPTLV----- 171
            +GE+ +  +P L         + P  L+ +   P      G  G    P FP +      
Sbjct: 1287 KGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV 1346

Query: 172  ---------PLHHGPPGASGVGSERDRKFQLHQT--PARGPPFPGISGMT--RGPVVLSG 218
                     P   GPPG  G+     +   +     P   P  PG+ G+   +GP  L G
Sbjct: 1347 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1406

Query: 219  VNRQHRWPPGASPSRS----LGEAGGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGP 273
                   PPG  P R+       AGG +    L  P  PG  G  GPPG  G+      P
Sbjct: 1407 PTG----PPG-DPGRNGLPGFDGAGGRKGDPGL--PGQPGTRGLDGPPGPDGLQGPPGPP 1459

Query: 274  GLARLA 279
            G + +A
Sbjct: 1460 GTSSVA 1465



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 60/230 (26%), Positives = 79/230 (34%), Gaps = 41/230 (17%)

Query: 71   RGITGCVNALGHRGSPEAVRGPGRGR--GPPNKAGRAA--GSPTRVQRRPRPLRPS---- 122
            +GI+G     G  G P  V G G     GPP + G+    G P    ++  P +P     
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192

Query: 123  --RAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHH--GPP 178
                 P L G++     P +   P            G  G +  P F     +    GPP
Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNP------------GLPGPKGEPGFHGFPGVQGPPGPP 1240

Query: 179  GASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEA 238
            G+ G   E  +     Q P   P   G  G+  GP            PPG   +  +   
Sbjct: 1241 GSPGPALEGPKGNPGPQGPPGRPGPTGFQGLP-GP----------EGPPGLPGNGGIKGE 1289

Query: 239  GGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGPGLARLAALGGLPSI 287
             G      L  P  PG  G  GPPG  G P     PGL  +    GLP +
Sbjct: 1290 KGNPGQPGL--PGLPGLKGDQGPPGLQGNPG---RPGLNGMKGDPGLPGV 1334



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 64/237 (27%), Positives = 79/237 (33%), Gaps = 69/237 (29%)

Query: 71  RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRG 130
           +GI GC    G RG P +   PG  +GPP   G                      P ++G
Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGL-QGPPGPPG---------------------IPGMKG 156

Query: 131 EEPSLLRPQLSRRPRALRRSTRVPA-AGKGGDR--RAPVFPTLVPLHHGPPGASGVGSER 187
           E  S++   L   P+        P   G  G      P+ P   P   GPPG  G+   +
Sbjct: 157 EPGSIIMSSLP-GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 188 DRKFQLHQTP--------ARGPPFP--------------------GISGMTRGPVVLSGV 219
                  Q P         +GPP P                    G+ G  RGP    G+
Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG-DRGPPGPPGI 274

Query: 220 NRQHRWPPGASPSRSLGEAG--GERPARALRRPRAPGRAGGGGPPGGGIPACSIGPG 274
               R PPG  P    GE G  GE   R       PG+ G  G P  GIP     PG
Sbjct: 275 ----RGPPG-PPGGEKGEKGEQGEPGKRG-----KPGKDGENGQP--GIPGLPGDPG 319



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 41/146 (28%), Positives = 51/146 (34%), Gaps = 34/146 (23%)

Query: 176 GPPGASGVGSERDRKFQLHQTPARG----------PPFPGISGMTRGPVVLSGV--NRQH 223
           GPPG+ G   ++  K Q   T  +G          P FPG  G     +   G+  ++  
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGE 562

Query: 224 RWPPGASPSRSL----------------GEAGG-----ER-PARALRRPRAPGRAGGGGP 261
              PGA     L                GE GG     ER P      P  PG  G  GP
Sbjct: 563 LGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP 622

Query: 262 PGGGIPACSIGPGLARLAALGGLPSI 287
           PG G P      G+  +A   G P I
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGI 648



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 86/306 (28%), Positives = 99/306 (32%), Gaps = 97/306 (31%)

Query: 5   PRSP-APGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQA 63
           P +P APG  GSK  GE  P   L     K    +G+  +  A   P L       Q   
Sbjct: 532 PGAPGAPGFPGSK--GE--PGDILTFPGMK--GDKGELGSPGAPGLPGLPGTPG--QDGL 583

Query: 64  PDLLLASRGITGCVNALGHRGSPEAVRGPGR----------GRGPPNKAGR-----AAGS 108
           P L    +G  G +   G RG P     PG           G GPP   G       AG+
Sbjct: 584 PGLP-GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 109 PTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFP 168
           P +    P P    +  P     +P   +P L   P       R    G  GD   P  P
Sbjct: 643 PGQ-PGIPGP----KGDPGQTITQPG--KPGLPGNPG------RDGDVGLPGDPGLPGQP 689

Query: 169 TL--VPLHHGPPGASGVGSERDRKFQLHQTPARGPP----FPGISGMTRGPVVLSGVNRQ 222
            L  +P   G PG  G+G               GPP    FPGI G              
Sbjct: 690 GLPGIPGSKGEPGIPGIGLP-------------GPPGPKGFPGIPG-------------- 722

Query: 223 HRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGPGLARLAAL 281
              PPGA                    P  PGR G  GPPG  G P     PG A     
Sbjct: 723 ---PPGA--------------------PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP 759

Query: 282 G--GLP 285
           G  GLP
Sbjct: 760 GPPGLP 765



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 63/225 (28%), Positives = 72/225 (32%), Gaps = 58/225 (25%)

Query: 67  LLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAP 126
           L   RG  G     G  G P   +G    +G P K G+                     P
Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK---------------------P 300

Query: 127 RLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
              GE      P L   P       R    G+ GD   P  P LV     P   +G+   
Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVI----PRPGTGITIG 356

Query: 187 RDRKFQLHQTPA----RGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAG--G 240
                 L   P     RG  FPGI    +GP  L G       PPGA+     G  G  G
Sbjct: 357 EKGNIGLPGLPGEKGERG--FPGI----QGPPGLPG-------PPGAAVMGPPGPPGFPG 403

Query: 241 ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP 285
           ER           G+ G  GPPG  IP     PGL       GLP
Sbjct: 404 ER-----------GQKGDEGPPGISIPG---PPGLDGQPGAPGLP 434


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 68/237 (28%), Positives = 89/237 (37%), Gaps = 38/237 (16%)

Query: 67   LLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAP 126
            L+   G+ G +  +G  G P+ V GP    G P + G + G P +   +  P   S   P
Sbjct: 1019 LIGPPGLKGTIGDMGFPG-PQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLP 1076

Query: 127  RLRGEEPSLLRPQLSRRPRALRRSTRVPAA----GKGGDRRAPVFPTLVPLHHGPPGASG 182
             L G +     P     P  ++ S   P      G  G +  P  P   P   GPPG  G
Sbjct: 1077 GLPGPKGEPGLPGYPGNP-GIKGSVGDPGLPGLPGTPGAKGQPGLPGF-PGTPGPPGPKG 1134

Query: 183  VGSERDRKFQLHQTPARGPPF-PGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGE 241
            +                GPP  PG+ G   GPV   G    H   PG  P    G+ G +
Sbjct: 1135 IS---------------GPPGNPGLPGEP-GPVGGGG----HPGQPG--PPGEKGKPGQD 1172

Query: 242  RPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESSRLLPSPR 298
                    P   G+ G  G PG G P     PGL+     GGLP I   +  LP P+
Sbjct: 1173 GI------PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGI-PGNPGLPGPK 1222



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 60/219 (27%), Positives = 70/219 (31%), Gaps = 58/219 (26%)

Query: 71   RGITGCVNALGHRGSPEAVRGPGRGR--GPPNKAGRAA--GSPTRVQRRPRPLRPSRAAP 126
            +GI+G     G  G P  V G G     GPP + G+    G P    ++  P +P    P
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192

Query: 127  RLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
               G       P LS               G+ GD   P  P       G PG  G    
Sbjct: 1193 GPPG------LPGLS---------------GQKGDGGLPGIP-------GNPGLPG---- 1220

Query: 187  RDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARA 246
                      P   P F G  G+   P            PPG+      G  G   P   
Sbjct: 1221 ----------PKGEPGFHGFPGVQGPP-----------GPPGSPGPALEGPKGNPGPQGP 1259

Query: 247  LRRPRAPGRAGGGGPPG-GGIPACSIGPGLARLAALGGL 284
              RP  PG  G  G PG GGI      PG   L  L GL
Sbjct: 1260 PGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 64/210 (30%), Positives = 71/210 (33%), Gaps = 35/210 (16%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQL 140
           G RG P    GP   RGPP   G   G     Q  P      R  P   GE      P L
Sbjct: 264 GDRGPP----GPPGIRGPPGPPGGEKGEKGE-QGEPG----KRGKPGKDGENGQPGIPGL 314

Query: 141 SRRPRALRRSTRVPAAGKGGDRRAPVFPTLV------PLHHGPPGASGV----GSERDRK 190
              P       R    G+ GD   P  P LV       +  G  G  G+    G + +R 
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 191 FQLHQTPARGPPFPGISGM-TRGPVVLSGVNRQH--RWPPGASPSRSLGEAGGERPARAL 247
           F   Q P   P  PG + M   GP    G   Q     PPG S     G  G        
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG-------- 426

Query: 248 RRPRAPGRAGGGGPPGGGIP----ACSIGP 273
            +P APG  G  GP G  IP     C  GP
Sbjct: 427 -QPGAPGLPGPPGPAGPHIPPSDEICEPGP 455



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 72/264 (27%), Positives = 85/264 (32%), Gaps = 68/264 (25%)

Query: 72  GITGCVNALGHRGSPE-AVRGPGRGRGPPNKAGR--AAGSPTRVQRRPRPLRPSRAAPRL 128
           G+ G   + G  G P   + GP   +G P   G   A G+P R+     P  P    P+ 
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK- 748

Query: 129 RGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP--------------------VFP 168
              EP    P     P          A G  GDR  P                    V P
Sbjct: 749 --GEPGFALPGPPGPPGLPGFKG---ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 169 TLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWP- 226
              P   GPPG  G+G              +GPP P GI G    P  L G+  +   P 
Sbjct: 804 NGQPGPMGPPGLPGIG-------------VQGPPGPPGIPGPIGQPG-LHGIPGEKGDPG 849

Query: 227 ------PGASPSR-SLGEAGGERPARALRRPRAPGRAGGGGPPGG--------------- 264
                 PG    R S G  G   P      P  PG+AG  G PG                
Sbjct: 850 PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 265 -GIPACSIGPGLARLAALGGLPSI 287
            GIP  S  PGL     L G P +
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGL 933



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 42/149 (28%), Positives = 54/149 (36%), Gaps = 34/149 (22%)

Query: 157 GKGGDRRAPVFPTL--VPLHHGPPGASGV-GSERDRKFQLHQTPARGPPFPGISGMTRGP 213
           G+ G   AP  P L   P   G PG  G  G      F+  + P   P  PG+ G   GP
Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI-GP 619

Query: 214 VVLSGVNRQHRWPPGASPSRSLGEAGGE----------------RPARALRRPRAPGRAG 257
           +           PPG  P   +GE G +                 P + + +P  PG  G
Sbjct: 620 M----------GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 258 GGGPPGG-GIPACSIGPGLARLAALGGLP 285
             G  G  G+P     PGL     L G+P
Sbjct: 670 NPGRDGDVGLPG---DPGLPGQPGLPGIP 695



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 56/206 (27%), Positives = 73/206 (35%), Gaps = 23/206 (11%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGR----GPPNKAGRAA--GSPTRVQRRPRPLRPSRAA 125
            GI G +   G  G P     PG       GPP + G     G+P  +     P  P +A 
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887

Query: 126  ----PRLRGEEPSLLRPQLSRRPRALRRSTRVPAA-GKGGDRRAPVFP--TLVPLHHGPP 178
                P  +GE   ++ P     P  +   + VP   G  G +  P  P  T      G P
Sbjct: 888  ASGFPGTKGEM-GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP 946

Query: 179  GASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSL-GE 237
            G  G     D      +     P  PGI G++ GP    G+       PG      L G+
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS-GPKGYQGL-------PGDPGQPGLSGQ 998

Query: 238  AGGERPARALRRPRAPGRAGGGGPPG 263
             G   P      P  PG+ G  GPPG
Sbjct: 999  PGLPGPPGPKGNPGLPGQPGLIGPPG 1024



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 64/237 (27%), Positives = 79/237 (33%), Gaps = 69/237 (29%)

Query: 71  RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRG 130
           +GI GC    G RG P +   PG  +GPP   G                      P ++G
Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGL-QGPPGPPG---------------------IPGMKG 156

Query: 131 EEPSLLRPQLSRRPRALRRSTRVPA-AGKGGDR--RAPVFPTLVPLHHGPPGASGVGSER 187
           E  S++   L   P+        P   G  G      P+ P   P   GPPG  G+   +
Sbjct: 157 EPGSIIMSSLP-GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 188 DRKFQLHQTP--------ARGPPFP--------------------GISGMTRGPVVLSGV 219
                  Q P         +GPP P                    G+ G  RGP    G+
Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG-DRGPPGPPGI 274

Query: 220 NRQHRWPPGASPSRSLGEAG--GERPARALRRPRAPGRAGGGGPPGGGIPACSIGPG 274
               R PPG  P    GE G  GE   R       PG+ G  G P  GIP     PG
Sbjct: 275 ----RGPPG-PPGGEKGEKGEQGEPGKRG-----KPGKDGENGQP--GIPGLPGDPG 319



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 41/146 (28%), Positives = 51/146 (34%), Gaps = 34/146 (23%)

Query: 176 GPPGASGVGSERDRKFQLHQTPARG----------PPFPGISGMTRGPVVLSGV--NRQH 223
           GPPG+ G   ++  K Q   T  +G          P FPG  G     +   G+  ++  
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGE 562

Query: 224 RWPPGASPSRSL----------------GEAGG-----ER-PARALRRPRAPGRAGGGGP 261
              PGA     L                GE GG     ER P      P  PG  G  GP
Sbjct: 563 LGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP 622

Query: 262 PGGGIPACSIGPGLARLAALGGLPSI 287
           PG G P      G+  +A   G P I
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGI 648



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 58/210 (27%), Positives = 83/210 (39%), Gaps = 34/210 (16%)

Query: 86   PEAVRG-PGRG-----RGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQ 139
            PE   G PG G     +G P + G       +  + P  L+ +   P L G +     P 
Sbjct: 1268 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1327

Query: 140  LSRRPRALRRSTRVP-AAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQT-- 196
            +   P  ++  + VP +AG  G+      P L+    GPPG  G+     +   +     
Sbjct: 1328 VPGFP-GMKGPSGVPGSAGPEGE------PGLI----GPPGPPGLPGPSGQSIIIKGDAG 1376

Query: 197  PARGPPFPGISGMT--RGPVVLSGVNRQHRWPPGASPSRS----LGEAGGERPARALRRP 250
            P   P  PG+ G+   +GP  L G       PPG  P R+       AGG +    L  P
Sbjct: 1377 PPGIPGQPGLKGLPGPQGPQGLPGPTG----PPG-DPGRNGLPGFDGAGGRKGDPGL--P 1429

Query: 251  RAPGRAGGGGPPG-GGIPACSIGPGLARLA 279
              PG  G  GPPG  G+      PG + +A
Sbjct: 1430 GQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 86/306 (28%), Positives = 99/306 (32%), Gaps = 97/306 (31%)

Query: 5   PRSP-APGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQA 63
           P +P APG  GSK  GE  P   L     K    +G+  +  A   P L       Q   
Sbjct: 532 PGAPGAPGFPGSK--GE--PGDILTFPGMK--GDKGELGSPGAPGLPGLPGTPG--QDGL 583

Query: 64  PDLLLASRGITGCVNALGHRGSPEAVRGPGR----------GRGPPNKAGR-----AAGS 108
           P L    +G  G +   G RG P     PG           G GPP   G       AG+
Sbjct: 584 PGLP-GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 109 PTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFP 168
           P +    P P    +  P     +P   +P L   P       R    G  GD   P  P
Sbjct: 643 PGQ-PGIPGP----KGDPGQTITQPG--KPGLPGNPG------RDGDVGLPGDPGLPGQP 689

Query: 169 TL--VPLHHGPPGASGVGSERDRKFQLHQTPARGPP----FPGISGMTRGPVVLSGVNRQ 222
            L  +P   G PG  G+G               GPP    FPGI G              
Sbjct: 690 GLPGIPGSKGEPGIPGIGLP-------------GPPGPKGFPGIPG-------------- 722

Query: 223 HRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGPGLARLAAL 281
              PPGA                    P  PGR G  GPPG  G P     PG A     
Sbjct: 723 ---PPGA--------------------PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP 759

Query: 282 G--GLP 285
           G  GLP
Sbjct: 760 GPPGLP 765



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 63/225 (28%), Positives = 72/225 (32%), Gaps = 58/225 (25%)

Query: 67  LLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAP 126
           L   RG  G     G  G P   +G    +G P K G+                     P
Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK---------------------P 300

Query: 127 RLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
              GE      P L   P       R    G+ GD   P  P LV     P   +G+   
Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVI----PRPGTGITIG 356

Query: 187 RDRKFQLHQTPA----RGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAG--G 240
                 L   P     RG  FPGI    +GP  L G       PPGA+     G  G  G
Sbjct: 357 EKGNIGLPGLPGEKGERG--FPGI----QGPPGLPG-------PPGAAVMGPPGPPGFPG 403

Query: 241 ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP 285
           ER           G+ G  GPPG  IP     PGL       GLP
Sbjct: 404 ER-----------GQKGDEGPPGISIPG---PPGLDGQPGAPGLP 434


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 68/237 (28%), Positives = 89/237 (37%), Gaps = 38/237 (16%)

Query: 67   LLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAP 126
            L+   G+ G +  +G  G P+ V GP    G P + G + G P +   +  P   S   P
Sbjct: 1019 LIGPPGLKGTIGDMGFPG-PQGVEGPPGPSGVPGQPG-SPGLPGQKGDKGDPGISSIGLP 1076

Query: 127  RLRGEEPSLLRPQLSRRPRALRRSTRVPAA----GKGGDRRAPVFPTLVPLHHGPPGASG 182
             L G +     P     P  ++ S   P      G  G +  P  P   P   GPPG  G
Sbjct: 1077 GLPGPKGEPGLPGYPGNP-GIKGSVGDPGLPGLPGTPGAKGQPGLPGF-PGTPGPPGPKG 1134

Query: 183  VGSERDRKFQLHQTPARGPPF-PGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGE 241
            +                GPP  PG+ G   GPV   G    H   PG  P    G+ G +
Sbjct: 1135 IS---------------GPPGNPGLPGEP-GPVGGGG----HPGQPG--PPGEKGKPGQD 1172

Query: 242  RPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESSRLLPSPR 298
                    P   G+ G  G PG G P     PGL+     GGLP I   +  LP P+
Sbjct: 1173 GI------PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGI-PGNPGLPGPK 1222



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 60/222 (27%), Positives = 70/222 (31%), Gaps = 61/222 (27%)

Query: 71   RGITGCVNALGHRGSPEAVRGPGRGR--GPPNKAGRAA--GSPTRVQRRPRPLRPSRAAP 126
            +GI+G     G  G P  V G G     GPP + G+    G P    ++  P +P    P
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192

Query: 127  RLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
               G       P LS               G+ GD   P  P       G PG  G    
Sbjct: 1193 GPPG------LPGLS---------------GQKGDGGLPGIP-------GNPGLPG---- 1220

Query: 187  RDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARA 246
                      P   P F G  G+   P            PPG+      G  G   P   
Sbjct: 1221 ----------PKGEPGFHGFPGVQGPP-----------GPPGSPGPALEGPKGNPGPQGP 1259

Query: 247  LRRPRAPGRAGGGGPPG----GGIPACSIGPGLARLAALGGL 284
              RP   G  G  GPPG    GGI      PG   L  L GL
Sbjct: 1260 PGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 64/210 (30%), Positives = 71/210 (33%), Gaps = 35/210 (16%)

Query: 81  GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQL 140
           G RG P    GP   RGPP   G   G     Q  P      R  P   GE      P L
Sbjct: 264 GDRGPP----GPPGIRGPPGPPGGEKGEKGE-QGEPG----KRGKPGKDGENGQPGIPGL 314

Query: 141 SRRPRALRRSTRVPAAGKGGDRRAPVFPTLV------PLHHGPPGASGV----GSERDRK 190
              P       R    G+ GD   P  P LV       +  G  G  G+    G + +R 
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 191 FQLHQTPARGPPFPGISGM-TRGPVVLSGVNRQH--RWPPGASPSRSLGEAGGERPARAL 247
           F   Q P   P  PG + M   GP    G   Q     PPG S     G  G        
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG-------- 426

Query: 248 RRPRAPGRAGGGGPPGGGIP----ACSIGP 273
            +P APG  G  GP G  IP     C  GP
Sbjct: 427 -QPGAPGLPGPPGPAGPHIPPSDEICEPGP 455



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 72/264 (27%), Positives = 85/264 (32%), Gaps = 68/264 (25%)

Query: 72  GITGCVNALGHRGSPE-AVRGPGRGRGPPNKAGR--AAGSPTRVQRRPRPLRPSRAAPRL 128
           G+ G   + G  G P   + GP   +G P   G   A G+P R+     P  P    P+ 
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK- 748

Query: 129 RGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAP--------------------VFP 168
              EP    P     P          A G  GDR  P                    V P
Sbjct: 749 --GEPGFALPGPPGPPGLPGFKG---ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 169 TLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWP- 226
              P   GPPG  G+G              +GPP P GI G    P  L G+  +   P 
Sbjct: 804 NGQPGPMGPPGLPGIG-------------VQGPPGPPGIPGPIGQPG-LHGIPGEKGDPG 849

Query: 227 ------PGASPSR-SLGEAGGERPARALRRPRAPGRAGGGGPPGG--------------- 264
                 PG    R S G  G   P      P  PG+AG  G PG                
Sbjct: 850 PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 265 -GIPACSIGPGLARLAALGGLPSI 287
            GIP  S  PGL     L G P +
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGL 933



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 42/149 (28%), Positives = 54/149 (36%), Gaps = 34/149 (22%)

Query: 157 GKGGDRRAPVFPTL--VPLHHGPPGASGV-GSERDRKFQLHQTPARGPPFPGISGMTRGP 213
           G+ G   AP  P L   P   G PG  G  G      F+  + P   P  PG+ G   GP
Sbjct: 561 GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI-GP 619

Query: 214 VVLSGVNRQHRWPPGASPSRSLGEAGGE----------------RPARALRRPRAPGRAG 257
           +           PPG  P   +GE G +                 P + + +P  PG  G
Sbjct: 620 M----------GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 258 GGGPPGG-GIPACSIGPGLARLAALGGLP 285
             G  G  G+P     PGL     L G+P
Sbjct: 670 NPGRDGDVGLPG---DPGLPGQPGLPGIP 695



 Score = 35.8 bits (81), Expect = 0.048
 Identities = 56/206 (27%), Positives = 73/206 (35%), Gaps = 23/206 (11%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGR----GPPNKAGRAA--GSPTRVQRRPRPLRPSRAA 125
            GI G +   G  G P     PG       GPP + G     G+P  +     P  P +A 
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887

Query: 126  ----PRLRGEEPSLLRPQLSRRPRALRRSTRVPAA-GKGGDRRAPVFP--TLVPLHHGPP 178
                P  +GE   ++ P     P  +   + VP   G  G +  P  P  T      G P
Sbjct: 888  ASGFPGTKGEM-GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP 946

Query: 179  GASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSL-GE 237
            G  G     D      +     P  PGI G++ GP    G+       PG      L G+
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVS-GPKGYQGL-------PGDPGQPGLSGQ 998

Query: 238  AGGERPARALRRPRAPGRAGGGGPPG 263
             G   P      P  PG+ G  GPPG
Sbjct: 999  PGLPGPPGPKGNPGLPGQPGLIGPPG 1024



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 64/237 (27%), Positives = 79/237 (33%), Gaps = 69/237 (29%)

Query: 71  RGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRG 130
           +GI GC    G RG P +   PG  +GPP   G                      P ++G
Sbjct: 119 QGIPGCNGTKGERGFPGSPGFPGL-QGPPGPPG---------------------IPGMKG 156

Query: 131 EEPSLLRPQLSRRPRALRRSTRVPA-AGKGGDR--RAPVFPTLVPLHHGPPGASGVGSER 187
           E  S++   L   P+        P   G  G      P+ P   P   GPPG  G+   +
Sbjct: 157 EPGSIIMSSLP-GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 188 DRKFQLHQTP--------ARGPPFP--------------------GISGMTRGPVVLSGV 219
                  Q P         +GPP P                    G+ G  RGP    G+
Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG-DRGPPGPPGI 274

Query: 220 NRQHRWPPGASPSRSLGEAG--GERPARALRRPRAPGRAGGGGPPGGGIPACSIGPG 274
               R PPG  P    GE G  GE   R       PG+ G  G P  GIP     PG
Sbjct: 275 ----RGPPG-PPGGEKGEKGEQGEPGKRG-----KPGKDGENGQP--GIPGLPGDPG 319



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 41/146 (28%), Positives = 51/146 (34%), Gaps = 34/146 (23%)

Query: 176 GPPGASGVGSERDRKFQLHQTPARG----------PPFPGISGMTRGPVVLSGV--NRQH 223
           GPPG+ G   ++  K Q   T  +G          P FPG  G     +   G+  ++  
Sbjct: 503 GPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGE 562

Query: 224 RWPPGASPSRSL----------------GEAGG-----ER-PARALRRPRAPGRAGGGGP 261
              PGA     L                GE GG     ER P      P  PG  G  GP
Sbjct: 563 LGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP 622

Query: 262 PGGGIPACSIGPGLARLAALGGLPSI 287
           PG G P      G+  +A   G P I
Sbjct: 623 PGFGPPGPVGEKGIQGVAGNPGQPGI 648



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 58/210 (27%), Positives = 83/210 (39%), Gaps = 34/210 (16%)

Query: 86   PEAVRG-PGRG-----RGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQ 139
            PE   G PG G     +G P + G       +  + P  L+ +   P L G +     P 
Sbjct: 1271 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1330

Query: 140  LSRRPRALRRSTRVP-AAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQT-- 196
            +   P  ++  + VP +AG  G+      P L+    GPPG  G+     +   +     
Sbjct: 1331 VPGFP-GMKGPSGVPGSAGPEGE------PGLI----GPPGPPGLPGPSGQSIIIKGDAG 1379

Query: 197  PARGPPFPGISGMT--RGPVVLSGVNRQHRWPPGASPSRS----LGEAGGERPARALRRP 250
            P   P  PG+ G+   +GP  L G       PPG  P R+       AGG +    L  P
Sbjct: 1380 PPGIPGQPGLKGLPGPQGPQGLPGPTG----PPG-DPGRNGLPGFDGAGGRKGDPGL--P 1432

Query: 251  RAPGRAGGGGPPG-GGIPACSIGPGLARLA 279
              PG  G  GPPG  G+      PG + +A
Sbjct: 1433 GQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 86/306 (28%), Positives = 99/306 (32%), Gaps = 97/306 (31%)

Query: 5   PRSP-APGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQA 63
           P +P APG  GSK  GE  P   L     K    +G+  +  A   P L       Q   
Sbjct: 532 PGAPGAPGFPGSK--GE--PGDILTFPGMK--GDKGELGSPGAPGLPGLPGTPG--QDGL 583

Query: 64  PDLLLASRGITGCVNALGHRGSPEAVRGPGR----------GRGPPNKAGR-----AAGS 108
           P L    +G  G +   G RG P     PG           G GPP   G       AG+
Sbjct: 584 PGLP-GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 109 PTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFP 168
           P +    P P    +  P     +P   +P L   P       R    G  GD   P  P
Sbjct: 643 PGQ-PGIPGP----KGDPGQTITQPG--KPGLPGNPG------RDGDVGLPGDPGLPGQP 689

Query: 169 TL--VPLHHGPPGASGVGSERDRKFQLHQTPARGPP----FPGISGMTRGPVVLSGVNRQ 222
            L  +P   G PG  G+G               GPP    FPGI G              
Sbjct: 690 GLPGIPGSKGEPGIPGIGLP-------------GPPGPKGFPGIPG-------------- 722

Query: 223 HRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPG-GGIPACSIGPGLARLAAL 281
              PPGA                    P  PGR G  GPPG  G P     PG A     
Sbjct: 723 ---PPGA--------------------PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP 759

Query: 282 G--GLP 285
           G  GLP
Sbjct: 760 GPPGLP 765



 Score = 32.0 bits (71), Expect = 0.69
 Identities = 63/225 (28%), Positives = 72/225 (32%), Gaps = 58/225 (25%)

Query: 67  LLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAP 126
           L   RG  G     G  G P   +G    +G P K G+                     P
Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGK---------------------P 300

Query: 127 RLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
              GE      P L   P       R    G+ GD   P  P LV     P   +G+   
Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVI----PRPGTGITIG 356

Query: 187 RDRKFQLHQTPA----RGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAG--G 240
                 L   P     RG  FPGI    +GP  L G       PPGA+     G  G  G
Sbjct: 357 EKGNIGLPGLPGEKGERG--FPGI----QGPPGLPG-------PPGAAVMGPPGPPGFPG 403

Query: 241 ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLP 285
           ER           G+ G  GPPG  IP     PGL       GLP
Sbjct: 404 ER-----------GQKGDEGPPGISIPG---PPGLDGQPGAPGLP 434


>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
            sapiens]
          Length = 2506

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 71/267 (26%), Positives = 91/267 (34%), Gaps = 56/267 (20%)

Query: 7    SPAPGLGGSK--KTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAP 64
            SPAP   G+   + G ++  QT   TPR H +     + A  +  P    +   +Q Q  
Sbjct: 2268 SPAPSTSGTSTPRRGRRQLPQT-PSTPRPHVSYSPVIRKAGGSGPPQQQQQQQ-QQQQQQ 2325

Query: 65   DLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRR-PRPLRP-S 122
             +    R  T      G R  P     P  G  PP   G ++G   R++RR P P R  S
Sbjct: 2326 AVARPGRAATS-----GPRRYPGPTAEPLAGDRPPT-GGHSSGRSPRMERRVPGPARSES 2379

Query: 123  RAAPRLRGEEPSLLRPQLSRRPRALRR----------STRVPAAGKGGDRRAPVFPTLVP 172
              A R  G       P +S  P   R               P +G G +  A  +    P
Sbjct: 2380 PRACRHGGARWPASGPHVSEGPPGPRHHGYYRGSDYDEADGPGSGGGEEAMAGAYDAPPP 2439

Query: 173  LHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPS 232
            + H   GA+G                R P  P  SG                 P  ASPS
Sbjct: 2440 VRHASSGATG----------------RSPRTPRASG-----------------PACASPS 2466

Query: 233  RSLGEA-GGERPARALRRPRAPGRAGG 258
            R       G  PA  L RPR PG   G
Sbjct: 2467 RHGRRLPNGYYPAHGLARPRGPGSRKG 2493



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 68/316 (21%), Positives = 105/316 (33%), Gaps = 68/316 (21%)

Query: 2    TAKPRSPAPGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQS 61
            T K R+  P +   ++ G++R    L++  R H  +R  + +A      +  P A  +++
Sbjct: 835  TNKSRAAEPTV--DQRLGQQRAEDFLRKQARYHDRARDPSGSAGL---DARRPWAGSQEA 889

Query: 62   QAPDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRP 121
            +     L+  G  G      H     ++  PG   G   + G+A     R   R    R 
Sbjct: 890  E-----LSREGPYG--RESDHHAREGSLEQPGFWEGEAER-GKAGDPHRRHVHRQGGSRE 941

Query: 122  SRAAPRLRGEEPSLLRPQLSRRP-----------RALRRSTRVPAAGKGGDRRAPVFPTL 170
            SR+     G +    R +  RRP           RA  R    PA G  G+   P     
Sbjct: 942  SRSGSPRTGADGEHRRHRAHRRPGEEGPEDKAERRARHREGSRPARGGEGEGEGPDGGER 1001

Query: 171  VPLH-HGPPGASGVGSERDRKFQLH----QTPARGPPFPGISGMTRGPV----------- 214
               H HG P      + R+ K + H    +    G P  G +  T  P+           
Sbjct: 1002 RRRHRHGAPATYEGDARREDKERRHRRRKENQGSGVPVSGPNLSTTRPIQQDLGRQDPPL 1061

Query: 215  ---VLSGVNRQHRWPPGASPSRSLGEAG-------------------------GERPARA 246
               + +  N +      A+P  SLG AG                           + A +
Sbjct: 1062 AEDIDNMKNNKLATAESAAPHGSLGHAGLPQSPAKMGNSTDPGPMLAIPAMATNPQNAAS 1121

Query: 247  LRRPRAPGRAGGGGPP 262
             R P  PG     GPP
Sbjct: 1122 RRTPNNPGNPSNPGPP 1137


>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 68/249 (27%), Positives = 90/249 (36%), Gaps = 53/249 (21%)

Query: 29  RTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAPDLLLASRGITGCVNALGHRGSPEA 88
           RT    A  RG     A  L+  ++P+  I+++Q P              A G R S   
Sbjct: 2   RTETNLAGDRGAEPGVANQLSHRILPQDGIKRAQPPP----------HTPATGTRSSYRL 51

Query: 89  VRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRP--QLSRRPRA 146
           +  P +GRG    A  A  S +R++R P   + S + PR       L  P   L RRPR 
Sbjct: 52  L--PQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRLASPAGDLPRRPR- 108

Query: 147 LRRSTRVPAAGKGGDRRAPVFPTLV------PLHHGPPGASGVGSERDRKFQLHQTPARG 200
                  P AG G     P   T+        L  G     G G  R    +  +  +R 
Sbjct: 109 -------PRAGGGRHSPRPAVGTIFRGGRKGRLREGRGAVRGSGKRRGWGLRPQRVRSR- 160

Query: 201 PPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPRAPG----RA 256
               G+ G  RG               GA+  R  G  G ER    + +P  P     R 
Sbjct: 161 --LAGL-GAPRG---------------GAAAPRGWGGQGAER--LGVHQPGLPTHAALRG 200

Query: 257 GGGGPPGGG 265
           GGGG  GGG
Sbjct: 201 GGGGSEGGG 209



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 72/233 (30%), Positives = 88/233 (37%), Gaps = 37/233 (15%)

Query: 5   PRSPAPGLGGSKKTGEKRPAQ-TLQRTPRK------HAASRGQAQAAAAALTPSLIPRAA 57
           PR P P  GG + +   RPA  T+ R  RK        A RG  +     L P  + R+ 
Sbjct: 104 PRRPRPRAGGGRHS--PRPAVGTIFRGGRKGRLREGRGAVRGSGKRRGWGLRPQRV-RSR 160

Query: 58  IRQSQAP-DLLLASRGITGC-VNALG--HRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQ 113
           +    AP     A RG  G     LG    G P      G G G     G A  SP R +
Sbjct: 161 LAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRAR 220

Query: 114 R------RPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTR-------VPAA---- 156
           +      RPR  R   +A R  G        QLSR   A+R S+R       V AA    
Sbjct: 221 QPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPT 280

Query: 157 --GKGGDRRAP--VFPTLVPLHHGPPGA-SGVGSERDRKFQLHQTPAR-GPPF 203
             G  G RRA          L  G P A  G+   R R+ + +  P R G PF
Sbjct: 281 RGGARGHRRADGRARGGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPF 333


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 65/237 (27%), Positives = 85/237 (35%), Gaps = 30/237 (12%)

Query: 71   RGITGCVNALGHRGSP--EAVRGPGRGRGPPNKAGRAAGSPTRVQRRPR------PLRPS 122
            +G  G V ++G  G+P     +GP    G P   G   G P  V  +        P  P 
Sbjct: 1159 KGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPG-GVGQPGAVGEKGERGDAGDPGPPG 1217

Query: 123  RAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASG 182
              AP + G +  +     S    A     +    G+ G  +  V PT +P   GPPG  G
Sbjct: 1218 --APGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDG-AKGSVGPTGLPGDLGPPGDPG 1274

Query: 183  V-GSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGA-SPSRSLGEAGG 240
            V G +     +       GP  PG SG    P            PPG   PS  +G  G 
Sbjct: 1275 VSGIDGSPGEKGDPGDVGGPGPPGASGEPGAP-----------GPPGKRGPSGHMGREGR 1323

Query: 241  ERPARALRRPRAPGRAGGGGPPGGGIPACSIGPGLARLAALGGLPSILESSRLLPSP 297
            E    A   P   G  G  GP G   P   +GP       L G+P  +    LL +P
Sbjct: 1324 EGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGP-----EGLRGIPGPVGEPGLLGAP 1375



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 84/295 (28%), Positives = 102/295 (34%), Gaps = 63/295 (21%)

Query: 5    PRSPAPGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAP 64
            P  P    G S KTG+  P    +R P      RGQ  A     T    P+  + Q  AP
Sbjct: 810  PLGPIGEKGKSGKTGQ--PGLEGERGPPGSRGERGQPGA-----TGQPGPKGDVGQDGAP 862

Query: 65   DL--------LLASRGITGCVNALGHRGSPEAVRGPG-RGR-------GPPNKAG----- 103
             +        L    G  G     GH+G       PG RG        GPP  AG     
Sbjct: 863  GIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQ 922

Query: 104  --RAAGSPTRVQRRPRPLRP--SRAAPRLRGEEPSL--LRPQ--LSRRPRALRRSTRVPA 155
                   P   +  P P  P   +  P L G E +   L P   L +   A  R    P 
Sbjct: 923  GKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPK 982

Query: 156  AGKGGDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVV 215
             G G        PT +    GPPG  G       +  L   PA G   PG SG + GPV 
Sbjct: 983  GGPGDPG-----PTGLKGDKGPPGPVGANGSPGERGPLG--PAGGIGLPGQSG-SEGPVG 1034

Query: 216  LSGV--NRQHRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGGGIPA 268
             +G   +R  R PPG +     G+ G             PG  G  GPPG   P+
Sbjct: 1035 PAGKKGSRGERGPPGPT-----GKDG------------IPGPLGPLGPPGAAGPS 1072



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 63/240 (26%), Positives = 80/240 (33%), Gaps = 44/240 (18%)

Query: 70   SRGITGCVNALGHRGSPEAVRGPGRG--RGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPR 127
            S G  G +  +G +G       PG    RGPP   G         Q  P+       AP 
Sbjct: 804  SIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPG 863

Query: 128  LRGEE--PSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTL-----VPLHHGPPGA 180
            + GE+  P L  P     P+        P   +G D R P  P            GPPG 
Sbjct: 864  IPGEKGLPGLQGPPGFPGPKG-------PPGHQGKDGR-PGHPGQRGELGFQGQTGPPGP 915

Query: 181  SGVGSERDRKFQLHQTPARGPP----------FPGISGM--------------TRGPVVL 216
            +GV   + +  ++     RGPP           PG+ G                 GP  L
Sbjct: 916  AGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGL 975

Query: 217  SGVNRQHRWPPGASPSRSLGEAGGERPARALRRP--RAP-GRAGGGGPPGGGIPACSIGP 273
             G       P    P+   G+ G   P  A   P  R P G AGG G PG       +GP
Sbjct: 976  RGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGP 1035



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 63/206 (30%), Positives = 76/206 (36%), Gaps = 47/206 (22%)

Query: 64   PDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSR 123
            P  +L  +G TG V  LG RG P    GP    GPP + G                    
Sbjct: 915  PAGVLGPQGKTGEVGPLGERGPP----GP---PGPPGEQG-------------------- 947

Query: 124  AAPRLRGEEPSL--LRP--QLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPG 179
              P L G E +   L P   L +   A  R    P  G G        PT +    GPPG
Sbjct: 948  -LPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPG-----PTGLKGDKGPPG 1001

Query: 180  ASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGV--NRQHRWPPGASPSRSLGE 237
              G       +  L   PA G   PG SG + GPV  +G   +R  R PPG +     G+
Sbjct: 1002 PVGANGSPGERGPL--GPAGGIGLPGQSG-SEGPVGPAGKKGSRGERGPPGPT-----GK 1053

Query: 238  AGGERPARALRRPRAPGRAGGGGPPG 263
             G   P   L  P A G +G  G  G
Sbjct: 1054 DGIPGPLGPLGPPGAAGPSGEEGDKG 1079



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 66/232 (28%), Positives = 77/232 (33%), Gaps = 55/232 (23%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGS----------PTRVQRRPRPLRP 121
            G  G     GH G P A    GR RGPP   G+              P  +Q  P P   
Sbjct: 1100 GQPGIRGPAGHPGPPGADGAQGR-RGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGE 1158

Query: 122  S-----------RAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTL 170
                          AP  RG +           P  + +   V   G+ GD   P     
Sbjct: 1159 KGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDP----- 1213

Query: 171  VPLHHGPPGASGV-GSERD--RKFQLHQTPARGPPF----PGISGM--TRGPVVLSGVNR 221
                 GPPGA G+ G + D   K     + A GPP     PG  G   + GP  L G   
Sbjct: 1214 -----GPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPG--- 1265

Query: 222  QHRWPPG--------ASPSRS--LGEAGGERPARALRRPRAPGRAGGGGPPG 263
                PPG         SP      G+ GG  P  A   P APG  G  GP G
Sbjct: 1266 -DLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSG 1316



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 57/207 (27%), Positives = 72/207 (34%), Gaps = 12/207 (5%)

Query: 72   GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGR--AAGSPTRVQRRPRPLRPSRAAPRLR 129
            G++G   + G +G P  V GPG    PP  +G   A G P +        R  R   +  
Sbjct: 1274 GVSGIDGSPGEKGDPGDVGGPG----PPGASGEPGAPGPPGKRGPSGHMGREGREGEKGA 1329

Query: 130  GEEPSLLRPQLSRRPRALRRST-RVPAAGKGGDRRAPVFPTLV--PLHHGPPGASGVGSE 186
              EP    P     P   R    RV   G  G       P L+  P   GPPG  G    
Sbjct: 1330 KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGL 1389

Query: 187  RDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARA 246
               K        +G    G+ G+  GP   +G       P    P    G+ G   P  +
Sbjct: 1390 PGLKGDTGPKGEKG--HIGLIGLI-GPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGS 1446

Query: 247  LRRPRAPGRAGGGGPPGGGIPACSIGP 273
            L  P  PG AG  G  G      S+GP
Sbjct: 1447 LGHPGPPGVAGPLGQKGSKGSPGSMGP 1473



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 51/180 (28%), Positives = 67/180 (37%), Gaps = 33/180 (18%)

Query: 68   LASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPR 127
            + +RG  G V   G RG P  V  PG   G P + G            P PL PS   P 
Sbjct: 1345 MGARGPPGRVGPEGLRGIPGPVGEPGL-LGAPGQMG-----------PPGPLGPS-GLPG 1391

Query: 128  LRGEEPSLLRPQLSRRPRALRRSTRVPA-AGKGGDR-----RAPVFPTLVP--------- 172
            L+G+      P+  +    L      P  AG+ GD+     + P  P   P         
Sbjct: 1392 LKGD----TGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSL 1447

Query: 173  LHHGPPGASGVGSERDRKFQLHQTPARGPPFP-GISGMTRGPVVLSGVNRQHRWPPGASP 231
             H GPPG +G   ++  K        RG   P G  G    P  L G+ R+ R+ P   P
Sbjct: 1448 GHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLP 1507



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 59/225 (26%), Positives = 76/225 (33%), Gaps = 51/225 (22%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGS----PTRVQRRPRPLRP--SRAA 125
           G+TG   A G +G+     GP    GPP + G         P  +   P    P  +   
Sbjct: 617 GVTGIDGAPGAKGNV----GPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGI 672

Query: 126 PRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGS 185
           P L G +  L  P               P   KG   + P      P + GP G  G   
Sbjct: 673 PGLPGSDGPLGHP-----------GHEGPTGEKGA--QGPPGSAGPPGYPGPRGVKGTSG 719

Query: 186 ERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGA----------SPSRSL 235
            R  + +  +    G  FPG     +G V L G     +  PGA           P    
Sbjct: 720 NRGLQGEKGEKGEDG--FPGF----KGDVGLKG----DQGKPGAPGPRGEDGPEGPKGQA 769

Query: 236 GEAGGERPARA------LRRPRAPGRAGGGGPPGG-GIPACSIGP 273
           G+AG E P  +      L  P  PG  G  GP G  G P   +GP
Sbjct: 770 GQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPG-PLGP 813



 Score = 29.3 bits (64), Expect = 4.5
 Identities = 64/212 (30%), Positives = 75/212 (35%), Gaps = 50/212 (23%)

Query: 72  GITGCVNALGHRGSPEAVRGPGRGRGPPNKAGR--AAGSPTRVQRRPRPLRPSRAAPRLR 129
           G+ G     G RG    V  PG    PP + G   A G P    +   P       PR  
Sbjct: 554 GLPGLPGEKGQRGDFGHVGQPG----PPGEDGERGAEGPPGPTGQAGEP------GPR-- 601

Query: 130 GEEPSLLRPQLSRRPRALRRSTRVPAA-GKGGDRRAPVFPTLVPLHHGPPGASGV-GSER 187
                LL P+ S  P      T +  A G  G+   P  P       GPPG  G  GS+ 
Sbjct: 602 ----GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEP-------GPPGQQGNHGSQG 650

Query: 188 DRKFQ-LHQTPA-RGPPF-PGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPA 244
               Q L  TP  +GPP  PGI G+                 PG+     LG  G E P 
Sbjct: 651 LPGPQGLIGTPGEKGPPGNPGIPGL-----------------PGSDGP--LGHPGHEGPT 691

Query: 245 RALRRPRAPGRAGGGGPPG-GGIPACSIGPGL 275
                   PG AG  G PG  G+   S   GL
Sbjct: 692 GEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGL 723


>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 68/249 (27%), Positives = 90/249 (36%), Gaps = 53/249 (21%)

Query: 29  RTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAPDLLLASRGITGCVNALGHRGSPEA 88
           RT    A  RG     A  L+  ++P+  I+++Q P              A G R S   
Sbjct: 2   RTETNLAGDRGAEPGVANQLSHRILPQDGIKRAQPPP----------HTPATGTRSSYRL 51

Query: 89  VRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRP--QLSRRPRA 146
           +  P +GRG    A  A  S +R++R P   + S + PR       L  P   L RRPR 
Sbjct: 52  L--PQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRLASPAGDLPRRPR- 108

Query: 147 LRRSTRVPAAGKGGDRRAPVFPTLV------PLHHGPPGASGVGSERDRKFQLHQTPARG 200
                  P AG G     P   T+        L  G     G G  R    +  +  +R 
Sbjct: 109 -------PRAGGGRHSPRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQRVRSR- 160

Query: 201 PPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPRAPG----RA 256
               G+ G  RG               GA+  R  G  G ER    + +P  P     R 
Sbjct: 161 --LAGL-GAPRG---------------GAAAPRGWGGQGAER--LGVHQPGLPTHAALRG 200

Query: 257 GGGGPPGGG 265
           GGGG  GGG
Sbjct: 201 GGGGSEGGG 209



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 72/233 (30%), Positives = 88/233 (37%), Gaps = 37/233 (15%)

Query: 5   PRSPAPGLGGSKKTGEKRPAQ-TLQRTPRK------HAASRGQAQAAAAALTPSLIPRAA 57
           PR P P  GG + +   RPA  T+ R  RK        A RG  +     L P  + R+ 
Sbjct: 104 PRRPRPRAGGGRHS--PRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQRV-RSR 160

Query: 58  IRQSQAP-DLLLASRGITGC-VNALG--HRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQ 113
           +    AP     A RG  G     LG    G P      G G G     G A  SP R +
Sbjct: 161 LAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRAR 220

Query: 114 R------RPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTR-------VPAA---- 156
           +      RPR  R   +A R  G        QLSR   A+R S+R       V AA    
Sbjct: 221 QPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPT 280

Query: 157 --GKGGDRRAP--VFPTLVPLHHGPPGA-SGVGSERDRKFQLHQTPAR-GPPF 203
             G  G RRA          L  G P A  G+   R R+ + +  P R G PF
Sbjct: 281 RGGARGHRRADGRARGGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPF 333


>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 68/249 (27%), Positives = 90/249 (36%), Gaps = 53/249 (21%)

Query: 29  RTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAPDLLLASRGITGCVNALGHRGSPEA 88
           RT    A  RG     A  L+  ++P+  I+++Q P              A G R S   
Sbjct: 2   RTETNLAGDRGAEPGVANQLSHRILPQDGIKRAQPPP----------HTPATGTRSSYRL 51

Query: 89  VRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRP--QLSRRPRA 146
           +  P +GRG    A  A  S +R++R P   + S + PR       L  P   L RRPR 
Sbjct: 52  L--PQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRLASPAGDLPRRPR- 108

Query: 147 LRRSTRVPAAGKGGDRRAPVFPTLV------PLHHGPPGASGVGSERDRKFQLHQTPARG 200
                  P AG G     P   T+        L  G     G G  R    +  +  +R 
Sbjct: 109 -------PRAGGGRHSPRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQRVRSR- 160

Query: 201 PPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPRAPG----RA 256
               G+ G  RG               GA+  R  G  G ER    + +P  P     R 
Sbjct: 161 --LAGL-GAPRG---------------GAAAPRGWGGQGAER--LGVHQPGLPTHAALRG 200

Query: 257 GGGGPPGGG 265
           GGGG  GGG
Sbjct: 201 GGGGSEGGG 209



 Score = 35.4 bits (80), Expect = 0.063
 Identities = 72/233 (30%), Positives = 88/233 (37%), Gaps = 37/233 (15%)

Query: 5   PRSPAPGLGGSKKTGEKRPAQ-TLQRTPRK------HAASRGQAQAAAAALTPSLIPRAA 57
           PR P P  GG + +   RPA  T+ R  RK        A RG  +     L P  + R+ 
Sbjct: 104 PRRPRPRAGGGRHS--PRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQRV-RSR 160

Query: 58  IRQSQAP-DLLLASRGITGC-VNALG--HRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQ 113
           +    AP     A RG  G     LG    G P      G G G     G A  SP R +
Sbjct: 161 LAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRAR 220

Query: 114 R------RPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTR-------VPAA---- 156
           +      RPR  R   +A R  G        QLSR   A+R S+R       V AA    
Sbjct: 221 QPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPT 280

Query: 157 --GKGGDRRAP--VFPTLVPLHHGPPGA-SGVGSERDRKFQLHQTPAR-GPPF 203
             G  G RRA          L  G P A  G+   R R+ + +  P R G PF
Sbjct: 281 RGGARGHRRADGRARGGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPF 333


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 77/276 (27%), Positives = 100/276 (36%), Gaps = 30/276 (10%)

Query: 3   AKPRSPAPGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQ 62
           A P +P+P    S   G    AQ +   P   AA+RG    AA    P L    ++ QS 
Sbjct: 338 APPAAPSPP--DSPAEGRLVKAQYI---PGAQAATRGLPGRAARRKPPPLTRGRSVEQSP 392

Query: 63  APDLLLASRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAG-------SPTRVQRR 115
             +   A+        A G RGSP A R   R +   +  GRA+         PT  +  
Sbjct: 393 PRERPRAAGRRGRMAEASGRRGSPRA-RKASRSQSETSLLGRASAVPSGPPKYPTAEREE 451

Query: 116 PRPLRPSRA-APRLRGEEPSLLRPQLSR----RPRALRRSTRVPAAGKGGDRRAPVFPTL 170
           PRP RP R  AP L  +     R   S          R   R PAA   G   +P  P  
Sbjct: 452 PRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQR 511

Query: 171 VPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPP--G 228
             L+    G +G  SE     +L     RGP     +G   G    S  +      P   
Sbjct: 512 RLLY----GCAGSDSECSAG-RLGPLGRRGP-----AGGVGGGYGESESSASEGESPAFS 561

Query: 229 ASPSRSLGEAGGERPARALRRPRAPGRAGGGGPPGG 264
           ++ S S G  G   P + +    A G   G G P G
Sbjct: 562 SASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAG 597



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 68/255 (26%), Positives = 91/255 (35%), Gaps = 43/255 (16%)

Query: 23  PAQTLQRTPRKHAASRGQAQAAAAA-LTPSLIPRAAIRQ--------SQAPDLLLASRGI 73
           P  T   +    A S  + +A A   LTPS +   A+R         + +PD   A R +
Sbjct: 190 PYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPL 249

Query: 74  TGCVNAL----GHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAPRLR 129
            G ++AL      RG+ +    PG   G P +       P      P   RP+R      
Sbjct: 250 DGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAR------ 303

Query: 130 GEEPSLLR-PQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSERD 188
             EPSL R       P AL R     A     +  A   P   P    PP +   G    
Sbjct: 304 --EPSLERVGGHPTSPAALSR-----AWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVK 356

Query: 189 RKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPSRSLGEA-GGERPARAL 247
            ++            PG    TRG   L G     R PP  +  RS+ ++   ERP  A 
Sbjct: 357 AQY-----------IPGAQAATRG---LPG-RAARRKPPPLTRGRSVEQSPPRERPRAAG 401

Query: 248 RRPRAPGRAGGGGPP 262
           RR R    +G  G P
Sbjct: 402 RRGRMAEASGRRGSP 416


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 67/272 (24%), Positives = 93/272 (34%), Gaps = 32/272 (11%)

Query: 10  PGLGGSKKTGEKRPAQTLQRTPRKHAASRGQAQAAAAALTPSLIPRAAIRQSQAPDLLLA 69
           PG GG ++ G   P + L        A++ +     +A + + +P AA   +  P+   A
Sbjct: 97  PGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAA-VAAGPEPAPA 155

Query: 70  SRGITGCVNALGHRGSPEAVRGPGRGRGPPNKAGRAAGSPTRVQRRPRPLRPSRAAP--- 126
                    AL  R  P    GPG G GP        G+   +      L    AA    
Sbjct: 156 GPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAV 215

Query: 127 RLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKGGDRRAPVFPTLVPLHHGPPGASGVGSE 186
            L    P+ L P    +P A     + P         AP  P+       PP A    + 
Sbjct: 216 SLVNNGPAALLPL--PKPAAPGTVIQTPPFVGAAAPPAPAAPS-------PPAAPAPAA- 265

Query: 187 RDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQHRWPPGASPS---RSLGEAGGERP 243
                     PA  PP P        P  L+        PP A+P+    +  + GG   
Sbjct: 266 ----------PAAAPPPP-----PPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAG 310

Query: 244 ARALRRPRAPGRAGGGGPPGGGIPACSIGPGL 275
           A     P A G AG  G PG G  A +  PG+
Sbjct: 311 AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGV 342



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 73/262 (27%), Positives = 89/262 (33%), Gaps = 51/262 (19%)

Query: 43  AAAAALTPSLIPRAAIRQSQAPDLLLASRGITGCVNALGHR---GSPEAVRGPGRGRGPP 99
           AA+AA    L PR        P++  A+ G      ALG+    GSP    G G      
Sbjct: 34  AASAAHHHHLAPRT-------PEVRAAAAG------ALGNHVVSGSPAGAAGAGPAAPAE 80

Query: 100 NKAGRAAGSPTRVQRRPRPLRPSRAAPRLRGEEPSLLRPQLSRRPRALRRSTRVPAAGKG 159
              G A   P   + RP    P R  P      PS  RP +   P       R P  G  
Sbjct: 81  GAPGAAPEPPPAGRARPGGGGPQRPGP------PSPRRPLVPAGPAPPAAKLRPPPEGSA 134

Query: 160 GDRRAPVFPTLVPLHHGPPGASGVGSERDRKFQLHQTPARGP-------PFPGISGMTRG 212
           G   APV P    +  GP  A    ++      L      GP       P PG  G   G
Sbjct: 135 GS-CAPV-PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG-PGKPAG 191

Query: 213 P---VVLSG----VNRQHRWPPGASPSRSLGEAGGERPARALRRPRAPGR-------AGG 258
           P     L+G    +N  H     A+P+ SL    G      L +P APG         G 
Sbjct: 192 PGAAQTLNGSAALLNSHH----AAAPAVSLVN-NGPAALLPLPKPAAPGTVIQTPPFVGA 246

Query: 259 GGPPGGGIPACSIGPGLARLAA 280
             PP    P+    P  A  AA
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAA 268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,977,576
Number of Sequences: 37866
Number of extensions: 1192231
Number of successful extensions: 11774
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 1002
Number of HSP's that attempted gapping in prelim test: 8035
Number of HSP's gapped (non-prelim): 3354
length of query: 303
length of database: 18,247,518
effective HSP length: 102
effective length of query: 201
effective length of database: 14,385,186
effective search space: 2891422386
effective search space used: 2891422386
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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