Search of human proteins with 169208667

Search of human proteins with 169208667

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]
         (266 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169208912 PREDICTED: hypothetical protein [Homo sapiens]           559   e-159
gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]           559   e-159
gi|169208084 PREDICTED: hypothetical protein [Homo sapiens]           556   e-159
gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]            50   2e-06
gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]            50   2e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    47   1e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    47   1e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      46   4e-05
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    46   4e-05
gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo ...    46   4e-05
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ...    46   4e-05
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]            46   4e-05
gi|239755873 PREDICTED: hypothetical protein [Homo sapiens]            45   7e-05
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]       45   7e-05
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        44   1e-04
gi|223633890 hypothetical protein LOC729956 [Homo sapiens]             43   2e-04
gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo ...    42   7e-04
gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo ...    42   7e-04
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             42   7e-04
gi|239756517 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001
gi|239755333 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001
gi|56606142 complement component 1, q subcomponent-like 4 [Homo ...    41   0.001
gi|5032105 small optic lobes [Homo sapiens]                            41   0.001
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001
gi|239743072 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001
gi|239508718 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom...    41   0.001
gi|24497460 Shaw-related voltage-gated potassium channel protein...    40   0.003
gi|23510368 homeobox D11 [Homo sapiens]                                39   0.004
gi|239753335 PREDICTED: hypothetical protein [Homo sapiens]            39   0.004

>gi|169208912 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score =  559 bits (1440), Expect = e-159
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP 60
           MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP
Sbjct: 1   MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP 60

Query: 61  AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI 120
           AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI
Sbjct: 61  AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI 120

Query: 121 FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPL 180
           FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPL
Sbjct: 121 FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPL 180

Query: 181 RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL 240
           RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL
Sbjct: 181 RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL 240

Query: 241 GAPGGHCTRALASTSRAPPRRGGDPG 266
           GAPGGHCTRALASTSRAPPRRGGDPG
Sbjct: 241 GAPGGHCTRALASTSRAPPRRGGDPG 266


>gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score =  559 bits (1440), Expect = e-159
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP 60
           MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP
Sbjct: 1   MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP 60

Query: 61  AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI 120
           AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI
Sbjct: 61  AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI 120

Query: 121 FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPL 180
           FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPL
Sbjct: 121 FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPL 180

Query: 181 RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL 240
           RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL
Sbjct: 181 RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL 240

Query: 241 GAPGGHCTRALASTSRAPPRRGGDPG 266
           GAPGGHCTRALASTSRAPPRRGGDPG
Sbjct: 241 GAPGGHCTRALASTSRAPPRRGGDPG 266


>gi|169208084 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score =  556 bits (1432), Expect = e-159
 Identities = 265/266 (99%), Positives = 265/266 (99%)

Query: 1   MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP 60
           MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP
Sbjct: 1   MLLPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGP 60

Query: 61  AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI 120
           AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI
Sbjct: 61  AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI 120

Query: 121 FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPL 180
           FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVR RRPL
Sbjct: 121 FLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRWRRPL 180

Query: 181 RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL 240
           RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL
Sbjct: 181 RPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGEL 240

Query: 241 GAPGGHCTRALASTSRAPPRRGGDPG 266
           GAPGGHCTRALASTSRAPPRRGGDPG
Sbjct: 241 GAPGGHCTRALASTSRAPPRRGGDPG 266


>gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 72/252 (28%), Positives = 87/252 (34%), Gaps = 58/252 (23%)

Query: 28  LRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGVS 87
           L R    PP  PPP  PG P     R   G  P    + GP G       SG  G  G  
Sbjct: 61  LYRVSAPPPAPPPPPPPGGPSRS-ERPRAGLRPGAFVSPGPLGRR--ASCSGRAGSAG-- 115

Query: 88  LTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWER 147
             +  S  + S+++   PAR+    A    LR F    +S   P  A  G R G     R
Sbjct: 116 -RLRCSAAALSAAQRGGPARAQVPPA----LRTFSPGPAS---PPRASPGGRPGSEARGR 167

Query: 148 PAAALRTRLP-------------------RLSWLPSAGPPRPGLSVRRRRPLRPGAVRKS 188
             A    R+P                   +L   P+ GPP PG+S   R P+    V + 
Sbjct: 168 SGAECARRVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQ 227

Query: 189 Q--PPG------------------LRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGER 228
              PPG                  LRR  A GRA  GG        G G  ACS   G  
Sbjct: 228 HRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGP------PGGGIPACSIGPGLA 281

Query: 229 RSRRAAGVPGEL 240
           R     G+P  L
Sbjct: 282 RLAALGGLPSIL 293



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 37/141 (26%), Positives = 45/141 (31%), Gaps = 33/141 (23%)

Query: 140 AGGLQWERPAAALRTRLP-----RLSWLPSAGPPRPGLSVRRRRPLRPGAVRKSQPPGLR 194
           AG   W RP  A+    P     R+S  P A PP                     PPG  
Sbjct: 40  AGSKLWRRPRGAVSAGAPGSPLYRVSAPPPAPPP-------------------PPPPGGP 80

Query: 195 RQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGG-------HC 247
            ++   RA L     V PG      +CS R G     R +         GG         
Sbjct: 81  SRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSAGRLRCSAAALSAAQRGGPARAQVPPA 140

Query: 248 TRALASTSRAPPRR--GGDPG 266
            R  +    +PPR   GG PG
Sbjct: 141 LRTFSPGPASPPRASPGGRPG 161



 Score = 29.3 bits (64), Expect = 3.7
 Identities = 51/187 (27%), Positives = 61/187 (32%), Gaps = 29/187 (15%)

Query: 16  AFTLDQRDGKQRLR-----RTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCG 70
           A +  QR G  R +     RT    P SPP A PG      R G E  G +G E      
Sbjct: 123 ALSAAQRGGPARAQVPPALRTFSPGPASPPRASPGG-----RPGSEARGRSGAECARRVP 177

Query: 71  AAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLR---IFLRTASS 127
              G   + G G          S         + PAR       S   R   +       
Sbjct: 178 LHHGPPGASGVG----------SERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQ 227

Query: 128 ELLPAIAPDGRRAGGLQWERPAAAL-RTRLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVR 186
              P  A   R  G    ERPA AL R R P  +     GPP  G+       + PG  R
Sbjct: 228 HRWPPGASPSRSLGEAGGERPARALRRPRAPGRA--GGGGPPGGGIPA---CSIGPGLAR 282

Query: 187 KSQPPGL 193
            +   GL
Sbjct: 283 LAALGGL 289


>gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 72/252 (28%), Positives = 87/252 (34%), Gaps = 58/252 (23%)

Query: 28  LRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGVS 87
           L R    PP  PPP  PG P     R   G  P    + GP G       SG  G  G  
Sbjct: 61  LYRVSAPPPAPPPPPPPGGPSRS-ERPRAGLRPGAFVSPGPLGRR--ASCSGRAGSAG-- 115

Query: 88  LTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWER 147
             +  S  + S+++   PAR+    A    LR F    +S   P  A  G R G     R
Sbjct: 116 -RLRCSAAALSAAQRGGPARAQVPPA----LRTFSPGPAS---PPRASPGGRPGSEARGR 167

Query: 148 PAAALRTRLP-------------------RLSWLPSAGPPRPGLSVRRRRPLRPGAVRKS 188
             A    R+P                   +L   P+ GPP PG+S   R P+    V + 
Sbjct: 168 SGAECARRVPLHHGPPGASGVGSERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQ 227

Query: 189 Q--PPG------------------LRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGER 228
              PPG                  LRR  A GRA  GG        G G  ACS   G  
Sbjct: 228 HRWPPGASPSRSLGEAGGERPARALRRPRAPGRAGGGGP------PGGGIPACSIGPGLA 281

Query: 229 RSRRAAGVPGEL 240
           R     G+P  L
Sbjct: 282 RLAALGGLPSIL 293



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 37/141 (26%), Positives = 45/141 (31%), Gaps = 33/141 (23%)

Query: 140 AGGLQWERPAAALRTRLP-----RLSWLPSAGPPRPGLSVRRRRPLRPGAVRKSQPPGLR 194
           AG   W RP  A+    P     R+S  P A PP                     PPG  
Sbjct: 40  AGSKLWRRPRGAVSAGAPGSPLYRVSAPPPAPPP-------------------PPPPGGP 80

Query: 195 RQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGG-------HC 247
            ++   RA L     V PG      +CS R G     R +         GG         
Sbjct: 81  SRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSAGRLRCSAAALSAAQRGGPARAQVPPA 140

Query: 248 TRALASTSRAPPRR--GGDPG 266
            R  +    +PPR   GG PG
Sbjct: 141 LRTFSPGPASPPRASPGGRPG 161



 Score = 29.3 bits (64), Expect = 3.7
 Identities = 51/187 (27%), Positives = 61/187 (32%), Gaps = 29/187 (15%)

Query: 16  AFTLDQRDGKQRLR-----RTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCG 70
           A +  QR G  R +     RT    P SPP A PG      R G E  G +G E      
Sbjct: 123 ALSAAQRGGPARAQVPPALRTFSPGPASPPRASPGG-----RPGSEARGRSGAECARRVP 177

Query: 71  AAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLR---IFLRTASS 127
              G   + G G          S         + PAR       S   R   +       
Sbjct: 178 LHHGPPGASGVG----------SERDRKFQLHQTPARGPPFPGISGMTRGPVVLSGVNRQ 227

Query: 128 ELLPAIAPDGRRAGGLQWERPAAAL-RTRLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVR 186
              P  A   R  G    ERPA AL R R P  +     GPP  G+       + PG  R
Sbjct: 228 HRWPPGASPSRSLGEAGGERPARALRRPRAPGRA--GGGGPPGGGIPA---CSIGPGLAR 282

Query: 187 KSQPPGL 193
            +   GL
Sbjct: 283 LAALGGL 289


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 67/243 (27%), Positives = 79/243 (32%), Gaps = 32/243 (13%)

Query: 13  PLGAFTLDQRDGKQRLRRTGRAPPQSP--PPAGPGAPGAPWRRGDEGP----GPAG---- 62
           P GA      DG+      G A P  P  P  GPG PGAP  +G+ GP    GP G    
Sbjct: 337 PAGAAGARGNDGQP-----GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 391

Query: 63  -GEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIF 121
            GE G P    P G ASG  G  G+      +     +     P              + 
Sbjct: 392 RGEPGTPGSPGPAG-ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 450

Query: 122 LRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPLR 181
            +  + E  P IA      G      PA             P   P   G   +R     
Sbjct: 451 PKGQTGE--PGIAGFKGEQGPKGEPGPAG------------PQGAPGPAGEEGKRGARGE 496

Query: 182 PGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELG 241
           PG V    PPG  R   G R   G      P    G    S   G + +    G PGE G
Sbjct: 497 PGGVGPIGPPG-ERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG 555

Query: 242 APG 244
            PG
Sbjct: 556 LPG 558



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 73/241 (30%), Positives = 81/241 (33%), Gaps = 36/241 (14%)

Query: 39   PPPAGP-GAPGAPWRRGDEG-PGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLS 96
            P PAG  GA GAP  RG+ G PGPAG    GP GA     A G  G  G           
Sbjct: 809  PGPAGSAGARGAPGERGETGPPGPAG--FAGPPGADGQPGAKGEQGEAGQK--------- 857

Query: 97   WSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRL 156
               +    P   S A        +   T       A  P G  A G     P AA R   
Sbjct: 858  -GDAGAPGPQGPSGAPGPQGPTGV---TGPKGARGAQGPPG--ATGF----PGAAGRVGP 907

Query: 157  PRLSWLPS-AGPPRP----------GLSVRRRRPLRPGAVRKSQPPGLRRQTAGGRARLG 205
            P  +  P   GPP P          G S    R   PG    + PPG  +   G     G
Sbjct: 908  PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG-EKGEPGDDGPSG 966

Query: 206  GARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGDP 265
                  P    G        G+R  R   G+PG  G PG       AS  R PP   G P
Sbjct: 967  AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG-ASGDRGPPGPVGPP 1025

Query: 266  G 266
            G
Sbjct: 1026 G 1026



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 67/238 (28%), Positives = 84/238 (35%), Gaps = 28/238 (11%)

Query: 41  PAGP-GAPGAPWRRGDEGPGPAGGEAG--GPCGAAPGGCASGGCGVMGVSLTVSLSFLSW 97
           P GP G PG P + GD+G     G+AG  GP G        G  G+ GV        L  
Sbjct: 238 PMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG 297

Query: 98  SSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWER----PAAALR 153
           +      P                  + S     +  P G R  GL  ER    PA A  
Sbjct: 298 AKGEAGAPGVKG-------------ESGSPGENGSPGPMGPR--GLPGERGRTGPAGAAG 342

Query: 154 TRLPRLSWLPSAGPPRP-GLSVRRRRPLRPGAVRKSQPPGLR--RQTAGGRARLGGARAV 210
            R       P AGPP P G +     P  PGA  ++ P G R      G R   G   + 
Sbjct: 343 ARGNDGQPGP-AGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSP 401

Query: 211 DPGTGWGHCACSRRRGERRSRRAAGVPGELGAPG--GHCTRALASTSRAPPRRGGDPG 266
            P    G+       G + S  A G+ G  G PG  G      A+    P  + G+PG
Sbjct: 402 GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 68/268 (25%), Positives = 90/268 (33%), Gaps = 27/268 (10%)

Query: 4    PEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEG-PGPAG 62
            P  S  +P P G      +DG +  R     P ++  P   G  G P  +G+ G  GP+G
Sbjct: 907  PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 966

Query: 63   GEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFL 122
             E  GP G  P G A G  G++G+                  P +  A  A   R     
Sbjct: 967  AE--GPPG--PQGLA-GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021

Query: 123  RTASSELLPAIAPDGRR----AGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRR 178
                    PA  P GR     A G      AA ++        + + G P P        
Sbjct: 1022 VGPPGLTGPAGEP-GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP-------- 1072

Query: 179  PLRPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPG 238
               PG+   + P G +    G R   G    + P    G       +G R  +  AG PG
Sbjct: 1073 ---PGSPGPAGPTGKQ----GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG 1125

Query: 239  ELGAPGGHCTRALASTSRAPPRRGGDPG 266
            E G  G      L      PP   GD G
Sbjct: 1126 ERGLKGHRGFTGLQGLP-GPPGPSGDQG 1152



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 26/57 (45%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 35  PPQSPPPAGPGAPGAPWRRGDEGP----GPAG--GEAGGPCGAAPGGCASGGCGVMG 85
           P +   P  PGA G   R GD GP    GP+G  GE G P    P G A G  GVMG
Sbjct: 548 PGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG-ARGQPGVMG 603



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 69/256 (26%), Positives = 79/256 (30%), Gaps = 33/256 (12%)

Query: 33  RAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGG--PCG-----AAPGGCASGG----C 81
           + P   P PAGP   GAP   G+EG   A GE GG  P G      APG     G     
Sbjct: 467 QGPKGEPGPAGP--QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA 524

Query: 82  GVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAG 141
           G  G       S L+        P R         R  +  R   +     + P G    
Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR-GLTGRPGDAGPQGKVGPSGAPGE 583

Query: 142 GLQWERPAAALRTRLPRLSWLPSA----GPPR-------PGLSVRRRRPLRPGAVRKSQP 190
             +   P        P +   P      G P        PG    R  P + G    + P
Sbjct: 584 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 643

Query: 191 PGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRA 250
           PG     AG     G   A  P    G        GE       GVPGE GAPG    R 
Sbjct: 644 PG----PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 699

Query: 251 LASTSRAPPRRGGDPG 266
                R  P   G PG
Sbjct: 700 ----ERGFPGERGSPG 711



 Score = 32.3 bits (72), Expect = 0.44
 Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 30  RTGRAPPQSPP--------PAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGC--ASG 79
           + G+A  + PP        P  PG PG    RG  G   A GEAG P      G    +G
Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 318

Query: 80  GCGVMG 85
             G MG
Sbjct: 319 SPGPMG 324



 Score = 32.3 bits (72), Expect = 0.44
 Identities = 75/304 (24%), Positives = 91/304 (29%), Gaps = 77/304 (25%)

Query: 3   LPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAG 62
           LP    H  +P G        G   ++    +P ++  P   G  G P  RG  GP  A 
Sbjct: 283 LPGVKGHRGYP-GLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 341

Query: 63  GEAG-----GPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCR 117
           G  G     GP G       +GG G  G                   P     A     R
Sbjct: 342 GARGNDGQPGPAGPPGPVGPAGGPGFPG------------------APGAKGEAGPTGAR 383

Query: 118 LRIFLRTASSELLPAIAPDGRRAGGLQWE-----RPAAALRTRLPRLSWLP----SAGPP 168
                            P+G  A G + E      P  A  +  P    +P    SAG P
Sbjct: 384 ----------------GPEG--AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 425

Query: 169 ----RPGLSVRRRRPLRPGAVRKSQPPGLRRQ--TAGGRARLGGARAVDPGTGWGHCACS 222
                PG    R  P   GA     P G   +   AG +   G      P    G    +
Sbjct: 426 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 485

Query: 223 RRRGERRSR------RAAGVPGELGAPGGH---CTRALASTSRAPPRRG----------- 262
              G+R +R         G PGE GAPG         LA    AP  RG           
Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 545

Query: 263 GDPG 266
           GDPG
Sbjct: 546 GDPG 549



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 71/280 (25%), Positives = 86/280 (30%), Gaps = 63/280 (22%)

Query: 33  RAPPQSPPPAG----PGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGG-----------CA 77
           R    +P P+G    PG PG P   G  G     GEAG P    P G            A
Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712

Query: 78  SGGCGVMGVSLTVSLSFLSWSSSRC------------RVPARSSAASACSCRLRIFLRTA 125
            G  G  G+  T        +S                +P    AA     +     R  
Sbjct: 713 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD---RGD 769

Query: 126 SSELLPAIAP--DGRR--AGGLQWERPAAALRTRLPRLSWLPSAGPPRP-------GLSV 174
             E  P  AP  DG R   G +    PA A   +          GPP P       G   
Sbjct: 770 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEK-------GEVGPPGPAGSAGARGAPG 822

Query: 175 RRRRPLRPGAVRKSQPPGLRRQ--------TAGGRARLGGARAVDPGTGWGHCACSRRRG 226
            R     PG    + PPG   Q         AG +   G      P    G    +   G
Sbjct: 823 ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 882

Query: 227 ERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGDPG 266
            + +R A G PG  G PG       A+    PP   G+PG
Sbjct: 883 PKGARGAQGPPGATGFPG-------AAGRVGPPGSNGNPG 915



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 67/242 (27%), Positives = 80/242 (33%), Gaps = 35/242 (14%)

Query: 32  GRAPPQSPPPAG--PGAPGAPWRRGDEG-PGPAG--GEAG--GPCGAAPGGCASGGCGVM 84
           G + P  PP A   PG  G P  RG  G  GP G  G+ G  GP G APG    GG G+ 
Sbjct: 732 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG-APG--KDGGRGLT 788

Query: 85  GVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQ 144
           G       +  +        P  + +A A                    AP  R   G  
Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARG------------------APGERGETG-- 828

Query: 145 WERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVRKSQPPGLRRQTAGGRARL 204
              P  A     P     P A     G + ++     PG    S  PG +  T G     
Sbjct: 829 --PPGPAGFAGPPGADGQPGA-KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT-GVTGPK 884

Query: 205 GGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGD 264
           G   A  P    G    + R G   S    G PG  G P G      A     PP R G+
Sbjct: 885 GARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG-PSGKDGPKGARGDSGPPGRAGE 943

Query: 265 PG 266
           PG
Sbjct: 944 PG 945



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 68/267 (25%), Positives = 84/267 (31%), Gaps = 73/267 (27%)

Query: 32   GRAPPQSPPPAG--PGAPGAP---------WRRGDEGP----------GPAG--GEAGGP 68
            G A    PP +   PG PG P           RGD GP          GPAG  GE G P
Sbjct: 900  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959

Query: 69   CGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSE 128
                P G A G  G  G++    +  L         P                       
Sbjct: 960  GDDGPSG-AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG------------------- 999

Query: 129  LLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPP----RPGLSVRRRRPLRPGA 184
              P+  P  + A G   +R                  GPP     PGL+     P R G+
Sbjct: 1000 --PSGEPGKQGAPGASGDR------------------GPPGPVGPPGLTGPAGEPGREGS 1039

Query: 185  VRKSQPPGLRRQTAGGRARLGGARAVD-PGTGW--GHCACSRRRGERRSRRAAGVPGELG 241
                 PPG R   AG +   G   AV  PG     G    +   G++  R  AG  G +G
Sbjct: 1040 PGADGPPG-RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMG 1098

Query: 242  APGGHCTRALASTS--RAPPRRGGDPG 266
              G    R +      R      G+PG
Sbjct: 1099 PSGPAGARGIQGPQGPRGDKGEAGEPG 1125



 Score = 31.2 bits (69), Expect = 0.98
 Identities = 22/48 (45%), Positives = 24/48 (50%), Gaps = 8/48 (16%)

Query: 36  PQSPP-PAGP-GAPGAPWRRGDEG----PGPAG--GEAGGPCGAAPGG 75
           P+ PP P GP G  G    RGD+G    PGP G  GE G P    P G
Sbjct: 118 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 165



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 21/53 (39%), Positives = 21/53 (39%), Gaps = 8/53 (15%)

Query: 41  PAGPGAPGAPWRRGDEGPGPAGGE-----AGG---PCGAAPGGCASGGCGVMG 85
           P  PG PG P   G  GP   GG      AGG     G A  G   G  G MG
Sbjct: 155 PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 207



 Score = 29.3 bits (64), Expect = 3.7
 Identities = 30/85 (35%), Positives = 34/85 (40%), Gaps = 10/85 (11%)

Query: 4   PEPSQHHPFPLGAFTLDQRDGKQRLR-RTGRAPPQSPPP--AGPGAPGAPWRRGDEGPGP 60
           P   Q  P P G       +GK+  R   G   P  PP     PG  G P + G  GP  
Sbjct: 475 PAGPQGAPGPAG------EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG 528

Query: 61  AGGEAGGPCGAAPGGCASGGCGVMG 85
           A GE  GP G A    A+G  G  G
Sbjct: 529 APGER-GPSGLAGPKGANGDPGRPG 552



 Score = 28.5 bits (62), Expect = 6.4
 Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 45   GAPGAPWRRGDEG-PGPAG--GEAGGPCGAAPGGCASGGCGVMG 85
            G PG P   GD+G  GPAG  G  G P    P G   G  G+ G
Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG-KDGANGIPG 1182



 Score = 28.5 bits (62), Expect = 6.4
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 14/58 (24%)

Query: 32   GRAPPQSPP-PAGP-------------GAPGAPWRRGDEGPGPAGGEAGGPCGAAPGG 75
            G + P+ PP P GP             G PG   R G+ GP    G  G P    P G
Sbjct: 1158 GPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 67/243 (27%), Positives = 79/243 (32%), Gaps = 32/243 (13%)

Query: 13  PLGAFTLDQRDGKQRLRRTGRAPPQSP--PPAGPGAPGAPWRRGDEGP----GPAG---- 62
           P GA      DG+      G A P  P  P  GPG PGAP  +G+ GP    GP G    
Sbjct: 268 PAGAAGARGNDGQP-----GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 322

Query: 63  -GEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIF 121
            GE G P    P G ASG  G  G+      +     +     P              + 
Sbjct: 323 RGEPGTPGSPGPAG-ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 381

Query: 122 LRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPLR 181
            +  + E  P IA      G      PA             P   P   G   +R     
Sbjct: 382 PKGQTGE--PGIAGFKGEQGPKGEPGPAG------------PQGAPGPAGEEGKRGARGE 427

Query: 182 PGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELG 241
           PG V    PPG  R   G R   G      P    G    S   G + +    G PGE G
Sbjct: 428 PGGVGPIGPPG-ERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG 486

Query: 242 APG 244
            PG
Sbjct: 487 LPG 489



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 73/241 (30%), Positives = 81/241 (33%), Gaps = 36/241 (14%)

Query: 39  PPPAGP-GAPGAPWRRGDEG-PGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLS 96
           P PAG  GA GAP  RG+ G PGPAG    GP GA     A G  G  G           
Sbjct: 740 PGPAGSAGARGAPGERGETGPPGPAG--FAGPPGADGQPGAKGEQGEAGQK--------- 788

Query: 97  WSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRL 156
              +    P   S A        +   T       A  P G  A G     P AA R   
Sbjct: 789 -GDAGAPGPQGPSGAPGPQGPTGV---TGPKGARGAQGPPG--ATGF----PGAAGRVGP 838

Query: 157 PRLSWLPS-AGPPRP----------GLSVRRRRPLRPGAVRKSQPPGLRRQTAGGRARLG 205
           P  +  P   GPP P          G S    R   PG    + PPG  +   G     G
Sbjct: 839 PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG-EKGEPGDDGPSG 897

Query: 206 GARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGDP 265
                 P    G        G+R  R   G+PG  G PG       AS  R PP   G P
Sbjct: 898 AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG-ASGDRGPPGPVGPP 956

Query: 266 G 266
           G
Sbjct: 957 G 957



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 67/238 (28%), Positives = 84/238 (35%), Gaps = 28/238 (11%)

Query: 41  PAGP-GAPGAPWRRGDEGPGPAGGEAG--GPCGAAPGGCASGGCGVMGVSLTVSLSFLSW 97
           P GP G PG P + GD+G     G+AG  GP G        G  G+ GV        L  
Sbjct: 169 PMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG 228

Query: 98  SSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWER----PAAALR 153
           +      P                  + S     +  P G R  GL  ER    PA A  
Sbjct: 229 AKGEAGAPGVKG-------------ESGSPGENGSPGPMGPR--GLPGERGRTGPAGAAG 273

Query: 154 TRLPRLSWLPSAGPPRP-GLSVRRRRPLRPGAVRKSQPPGLR--RQTAGGRARLGGARAV 210
            R       P AGPP P G +     P  PGA  ++ P G R      G R   G   + 
Sbjct: 274 ARGNDGQPGP-AGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSP 332

Query: 211 DPGTGWGHCACSRRRGERRSRRAAGVPGELGAPG--GHCTRALASTSRAPPRRGGDPG 266
            P    G+       G + S  A G+ G  G PG  G      A+    P  + G+PG
Sbjct: 333 GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 68/268 (25%), Positives = 90/268 (33%), Gaps = 27/268 (10%)

Query: 4    PEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEG-PGPAG 62
            P  S  +P P G      +DG +  R     P ++  P   G  G P  +G+ G  GP+G
Sbjct: 838  PPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 897

Query: 63   GEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFL 122
             E  GP G  P G A G  G++G+                  P +  A  A   R     
Sbjct: 898  AE--GPPG--PQGLA-GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952

Query: 123  RTASSELLPAIAPDGRR----AGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRR 178
                    PA  P GR     A G      AA ++        + + G P P        
Sbjct: 953  VGPPGLTGPAGEP-GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP-------- 1003

Query: 179  PLRPGAVRKSQPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPG 238
               PG+   + P G +    G R   G    + P    G       +G R  +  AG PG
Sbjct: 1004 ---PGSPGPAGPTGKQ----GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG 1056

Query: 239  ELGAPGGHCTRALASTSRAPPRRGGDPG 266
            E G  G      L      PP   GD G
Sbjct: 1057 ERGLKGHRGFTGLQGLP-GPPGPSGDQG 1083



 Score = 35.0 bits (79), Expect = 0.068
 Identities = 26/57 (45%), Positives = 28/57 (49%), Gaps = 7/57 (12%)

Query: 35  PPQSPPPAGPGAPGAPWRRGDEGP----GPAG--GEAGGPCGAAPGGCASGGCGVMG 85
           P +   P  PGA G   R GD GP    GP+G  GE G P    P G A G  GVMG
Sbjct: 479 PGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG-ARGQPGVMG 534



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 69/256 (26%), Positives = 79/256 (30%), Gaps = 33/256 (12%)

Query: 33  RAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGG--PCG-----AAPGGCASGG----C 81
           + P   P PAGP   GAP   G+EG   A GE GG  P G      APG     G     
Sbjct: 398 QGPKGEPGPAGP--QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA 455

Query: 82  GVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAG 141
           G  G       S L+        P R         R  +  R   +     + P G    
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR-GLTGRPGDAGPQGKVGPSGAPGE 514

Query: 142 GLQWERPAAALRTRLPRLSWLPSA----GPPR-------PGLSVRRRRPLRPGAVRKSQP 190
             +   P        P +   P      G P        PG    R  P + G    + P
Sbjct: 515 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 574

Query: 191 PGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRA 250
           PG     AG     G   A  P    G        GE       GVPGE GAPG    R 
Sbjct: 575 PG----PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 630

Query: 251 LASTSRAPPRRGGDPG 266
                R  P   G PG
Sbjct: 631 ----ERGFPGERGSPG 642



 Score = 32.3 bits (72), Expect = 0.44
 Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 30  RTGRAPPQSPP--------PAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGC--ASG 79
           + G+A  + PP        P  PG PG    RG  G   A GEAG P      G    +G
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249

Query: 80  GCGVMG 85
             G MG
Sbjct: 250 SPGPMG 255



 Score = 32.3 bits (72), Expect = 0.44
 Identities = 75/304 (24%), Positives = 91/304 (29%), Gaps = 77/304 (25%)

Query: 3   LPEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAG 62
           LP    H  +P G        G   ++    +P ++  P   G  G P  RG  GP  A 
Sbjct: 214 LPGVKGHRGYP-GLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272

Query: 63  GEAG-----GPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCR 117
           G  G     GP G       +GG G  G                   P     A     R
Sbjct: 273 GARGNDGQPGPAGPPGPVGPAGGPGFPG------------------APGAKGEAGPTGAR 314

Query: 118 LRIFLRTASSELLPAIAPDGRRAGGLQWE-----RPAAALRTRLPRLSWLP----SAGPP 168
                            P+G  A G + E      P  A  +  P    +P    SAG P
Sbjct: 315 ----------------GPEG--AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 356

Query: 169 ----RPGLSVRRRRPLRPGAVRKSQPPGLRRQ--TAGGRARLGGARAVDPGTGWGHCACS 222
                PG    R  P   GA     P G   +   AG +   G      P    G    +
Sbjct: 357 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416

Query: 223 RRRGERRSR------RAAGVPGELGAPGGH---CTRALASTSRAPPRRG----------- 262
              G+R +R         G PGE GAPG         LA    AP  RG           
Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN 476

Query: 263 GDPG 266
           GDPG
Sbjct: 477 GDPG 480



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 71/280 (25%), Positives = 86/280 (30%), Gaps = 63/280 (22%)

Query: 33  RAPPQSPPPAG----PGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGG-----------CA 77
           R    +P P+G    PG PG P   G  G     GEAG P    P G            A
Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643

Query: 78  SGGCGVMGVSLTVSLSFLSWSSSRC------------RVPARSSAASACSCRLRIFLRTA 125
            G  G  G+  T        +S                +P    AA     +     R  
Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD---RGD 700

Query: 126 SSELLPAIAP--DGRR--AGGLQWERPAAALRTRLPRLSWLPSAGPPRP-------GLSV 174
             E  P  AP  DG R   G +    PA A   +          GPP P       G   
Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEK-------GEVGPPGPAGSAGARGAPG 753

Query: 175 RRRRPLRPGAVRKSQPPGLRRQ--------TAGGRARLGGARAVDPGTGWGHCACSRRRG 226
            R     PG    + PPG   Q         AG +   G      P    G    +   G
Sbjct: 754 ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 813

Query: 227 ERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGDPG 266
            + +R A G PG  G PG       A+    PP   G+PG
Sbjct: 814 PKGARGAQGPPGATGFPG-------AAGRVGPPGSNGNPG 846



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 67/242 (27%), Positives = 80/242 (33%), Gaps = 35/242 (14%)

Query: 32  GRAPPQSPPPAG--PGAPGAPWRRGDEG-PGPAG--GEAG--GPCGAAPGGCASGGCGVM 84
           G + P  PP A   PG  G P  RG  G  GP G  G+ G  GP G APG    GG G+ 
Sbjct: 663 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG-APG--KDGGRGLT 719

Query: 85  GVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQ 144
           G       +  +        P  + +A A                    AP  R   G  
Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARG------------------APGERGETG-- 759

Query: 145 WERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVRKSQPPGLRRQTAGGRARL 204
              P  A     P     P A     G + ++     PG    S  PG +  T G     
Sbjct: 760 --PPGPAGFAGPPGADGQPGA-KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT-GVTGPK 815

Query: 205 GGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGD 264
           G   A  P    G    + R G   S    G PG  G P G      A     PP R G+
Sbjct: 816 GARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG-PSGKDGPKGARGDSGPPGRAGE 874

Query: 265 PG 266
           PG
Sbjct: 875 PG 876



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 68/267 (25%), Positives = 84/267 (31%), Gaps = 73/267 (27%)

Query: 32   GRAPPQSPPPAG--PGAPGAP---------WRRGDEGP----------GPAG--GEAGGP 68
            G A    PP +   PG PG P           RGD GP          GPAG  GE G P
Sbjct: 831  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 890

Query: 69   CGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSE 128
                P G A G  G  G++    +  L         P                       
Sbjct: 891  GDDGPSG-AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG------------------- 930

Query: 129  LLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPP----RPGLSVRRRRPLRPGA 184
              P+  P  + A G   +R                  GPP     PGL+     P R G+
Sbjct: 931  --PSGEPGKQGAPGASGDR------------------GPPGPVGPPGLTGPAGEPGREGS 970

Query: 185  VRKSQPPGLRRQTAGGRARLGGARAVD-PGTGW--GHCACSRRRGERRSRRAAGVPGELG 241
                 PPG R   AG +   G   AV  PG     G    +   G++  R  AG  G +G
Sbjct: 971  PGADGPPG-RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMG 1029

Query: 242  APGGHCTRALASTS--RAPPRRGGDPG 266
              G    R +      R      G+PG
Sbjct: 1030 PSGPAGARGIQGPQGPRGDKGEAGEPG 1056



 Score = 31.2 bits (69), Expect = 0.98
 Identities = 22/48 (45%), Positives = 24/48 (50%), Gaps = 8/48 (16%)

Query: 36 PQSPP-PAGP-GAPGAPWRRGDEG----PGPAG--GEAGGPCGAAPGG 75
          P+ PP P GP G  G    RGD+G    PGP G  GE G P    P G
Sbjct: 49 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 96



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 21/53 (39%), Positives = 21/53 (39%), Gaps = 8/53 (15%)

Query: 41  PAGPGAPGAPWRRGDEGPGPAGGE-----AGG---PCGAAPGGCASGGCGVMG 85
           P  PG PG P   G  GP   GG      AGG     G A  G   G  G MG
Sbjct: 86  PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138



 Score = 29.3 bits (64), Expect = 3.7
 Identities = 30/85 (35%), Positives = 34/85 (40%), Gaps = 10/85 (11%)

Query: 4   PEPSQHHPFPLGAFTLDQRDGKQRLR-RTGRAPPQSPPP--AGPGAPGAPWRRGDEGPGP 60
           P   Q  P P G       +GK+  R   G   P  PP     PG  G P + G  GP  
Sbjct: 406 PAGPQGAPGPAG------EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG 459

Query: 61  AGGEAGGPCGAAPGGCASGGCGVMG 85
           A GE  GP G A    A+G  G  G
Sbjct: 460 APGER-GPSGLAGPKGANGDPGRPG 483



 Score = 28.5 bits (62), Expect = 6.4
 Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 4/44 (9%)

Query: 45   GAPGAPWRRGDEG-PGPAG--GEAGGPCGAAPGGCASGGCGVMG 85
            G PG P   GD+G  GPAG  G  G P    P G   G  G+ G
Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG-KDGANGIPG 1113



 Score = 28.5 bits (62), Expect = 6.4
 Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 14/58 (24%)

Query: 32   GRAPPQSPP-PAGP-------------GAPGAPWRRGDEGPGPAGGEAGGPCGAAPGG 75
            G + P+ PP P GP             G PG   R G+ GP    G  G P    P G
Sbjct: 1089 GPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 76/256 (29%), Positives = 84/256 (32%), Gaps = 75/256 (29%)

Query: 33   RAPPQSPPPAG----PGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCAS--GGCGVMGV 86
            R  P  P PAG    PGA G P  +G+ G   A G+AG P  A P G     G  G  G 
Sbjct: 802  RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGA 861

Query: 87   SLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWE 146
                               AR SA                        P G  A G    
Sbjct: 862  K-----------------GARGSA-----------------------GPPG--ATGF--- 876

Query: 147  RPAAALRTRLPRLSWLPSAGPPRP----------GLSVRRRRPLRPGAVRKSQPPGLRRQ 196
             P AA R   P  S   +AGPP P          G         RPG V    PPG    
Sbjct: 877  -PGAAGRVGPPGPS--GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG---- 929

Query: 197  TAGGRARLGG-ARAVDPGTGWGHCACSRR-----RGERRSRRAAGVPGELGAPGGHCTRA 250
             AG +   G    A  PGT        +R      G+R  R   G+PG  G PG      
Sbjct: 930  PAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSG 989

Query: 251  LASTSRAPPRRGGDPG 266
             AS  R PP   G PG
Sbjct: 990  -ASGERGPPGPMGPPG 1004



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 32/73 (43%), Positives = 34/73 (46%), Gaps = 16/73 (21%)

Query: 31  TGRAPPQSP-----PPAGPGAPGAPWRRGDEGP----GPAG--GEAG--GPCGAA-PGG- 75
           TG A P  P     PP  PGA GA    G +GP    GP G  GE G  GP GAA P G 
Sbjct: 328 TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387

Query: 76  -CASGGCGVMGVS 87
             A G  G  G +
Sbjct: 388 PGADGQPGAKGAN 400



 Score = 36.2 bits (82), Expect = 0.031
 Identities = 24/66 (36%), Positives = 26/66 (39%), Gaps = 2/66 (3%)

Query: 22   RDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAG--GPCGAAPGGCASG 79
            RDG    +        + PP  PGAPGAP   G  G     GE G  GP G      A G
Sbjct: 1026 RDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARG 1085

Query: 80   GCGVMG 85
              G  G
Sbjct: 1086 PAGPQG 1091



 Score = 34.7 bits (78), Expect = 0.089
 Identities = 72/272 (26%), Positives = 84/272 (30%), Gaps = 65/272 (23%)

Query: 32  GRAPPQSPP-PAGP----GAPGAPWRRGDEG----PGPAGGEAGGPCGAAPGGCASGGCG 82
           G + PQ P  P GP    G PGAP  +GD G    PGP G +  GP G A      G  G
Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ--GPPGPAGEEGKRGARG 473

Query: 83  VMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGG 142
             G +                 P     A             A     P   P G +   
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG--------PAGERGSP--GPAGPKGSP 523

Query: 143 LQWERPAAALRTRLPRLSWLPSAGPP-----RPGLSVRRRRPLRPGAVRKSQPPGLRRQT 197
            +  RP  A       L+  P +  P      PG + +  RP  PG      PPG R Q 
Sbjct: 524 GEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG------PPGARGQA 577

Query: 198 -----------------AGGRARLGGARAVDPGTGWGHCAC------SRRRGERRSRRAA 234
                            AG R   G   AV P    G          +   GER  +  A
Sbjct: 578 GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPA 637

Query: 235 GVPGELGAPGGHCTRALASTSRAPPRRGGDPG 266
           G PG  G PG             PP   G PG
Sbjct: 638 GSPGFQGLPG----------PAGPPGEAGKPG 659



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 69/254 (27%), Positives = 84/254 (33%), Gaps = 39/254 (15%)

Query: 35  PPQSP-------PPAGPGAPGAPWRRGDEG-PGPAG-----GEAG--------GPCGAAP 73
           PP +P       PP  PG PGA    G  G PGP G     GEAG        GP G   
Sbjct: 192 PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQG 251

Query: 74  GGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAI 133
                G  G+ G+      S L  +      PA                  A  ++ P  
Sbjct: 252 ARGLPGTAGLPGMKGHRGFSGLDGAKGDAG-PAGPKGEPGSPGE-----NGAPGQMGPRG 305

Query: 134 APDGRRAGGLQWERPAAALRTRLPRLSWLPSAGPPRP-GLSVRRRRPLRPGAVRKSQPPG 192
            P  R   G     PA A            +AGPP P G +     P   GA  ++ P G
Sbjct: 306 LPGERGRPGA--PGPAGARGND----GATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQG 359

Query: 193 LRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALA 252
             R + G +   G      P    G        G+  ++ A G PG  GAPG    R   
Sbjct: 360 -PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG-- 416

Query: 253 STSRAPPRRGGDPG 266
                P   GG PG
Sbjct: 417 --PSGPQGPGGPPG 428



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 23/59 (38%), Positives = 28/59 (47%), Gaps = 5/59 (8%)

Query: 32  GRAPPQSPPPAGP----GAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGV 86
           G+ P     PAG     G PG P   G++G   A G AG P    P G A G  GV+G+
Sbjct: 906 GKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIA-GQRGVVGL 963



 Score = 33.1 bits (74), Expect = 0.26
 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 2/54 (3%)

Query: 34   APPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCA--SGGCGVMG 85
            AP     P   G+PGA   RG+ GP    G  G P    P G A  SG  G  G
Sbjct: 1017 APGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETG 1070



 Score = 32.7 bits (73), Expect = 0.34
 Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 12/54 (22%)

Query: 32  GRAPPQSPPPAG----PGAPGAPWRRGDEGP----GPAG--GEAGGPCGAAPGG 75
           GR  P  P P+G    PG PG   + G +GP    GPAG  GE G P    P G
Sbjct: 881 GRVGP--PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAG 932



 Score = 32.3 bits (72), Expect = 0.44
 Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 7/58 (12%)

Query: 30  RTGRAPPQSPP-PAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGV 86
           + G A  Q PP PAGP        RG++GP  + G  G P  A P G  +G  G  GV
Sbjct: 612 KDGEAGAQGPPGPAGPAG-----ERGEQGPAGSPGFQGLPGPAGPPG-EAGKPGEQGV 663



 Score = 32.3 bits (72), Expect = 0.44
 Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 2/55 (3%)

Query: 35   PPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAG--GPCGAAPGGCASGGCGVMGVS 87
            P +S     PGA G+P R G  G     GE G  GP GA     A G  G  G S
Sbjct: 1009 PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS 1063



 Score = 32.0 bits (71), Expect = 0.58
 Identities = 64/245 (26%), Positives = 79/245 (32%), Gaps = 14/245 (5%)

Query: 8   QHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEG-PGPAGGEAG 66
           Q  P P G    +   G    +    AP        PG  G P  RG  G PGP G    
Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDR-- 745

Query: 67  GPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTAS 126
           G  G      + G  GV G++  +     + +         S  A     R     R   
Sbjct: 746 GDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEP 805

Query: 127 SELLPA--IAPDGRRA-GGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPLRPG 183
               PA    P G     G + E   A  +           AGPP P  +V    P   G
Sbjct: 806 GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNV--GAPGAKG 863

Query: 184 AVRKSQPPGLRRQTAGGRARLG----GARAVDPGTGWGHCACSRRRGERRSRRAAGVPGE 239
           A   + PPG      G   R+G       A  PG   G       +G R     AG PGE
Sbjct: 864 ARGSAGPPG-ATGFPGAAGRVGPPGPSGNAGPPGPP-GPAGKEGGKGPRGETGPAGRPGE 921

Query: 240 LGAPG 244
           +G PG
Sbjct: 922 VGPPG 926



 Score = 32.0 bits (71), Expect = 0.58
 Identities = 17/43 (39%), Positives = 18/43 (41%)

Query: 35   PPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCA 77
            P Q      PG PG     G +GP  A GE G P    P G A
Sbjct: 964  PGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 4/67 (5%)

Query: 23  DGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEG-PGPAG--GEAGGPCGAAPGGCASG 79
           DG+   +    AP  +  P  PGA G    +G  G PGP G  GE G P      G A G
Sbjct: 391 DGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTG-AKG 449

Query: 80  GCGVMGV 86
             G +GV
Sbjct: 450 EPGPVGV 456



 Score = 31.6 bits (70), Expect = 0.75
 Identities = 69/254 (27%), Positives = 85/254 (33%), Gaps = 48/254 (18%)

Query: 4   PEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPA---GPGAPGAPWRRGDEGPGP 60
           P   Q  P P G       +GK+  R          PP    GPG+ G P   G  GP  
Sbjct: 453 PVGVQGPPGPAG------EEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG 506

Query: 61  AGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRI 120
             GE G P  A P G + G  G  G +       L+ S        ++            
Sbjct: 507 PAGERGSPGPAGPKG-SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAG----- 560

Query: 121 FLRTASSELLPAIAPDGR-RAGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRP 179
                     P   P  R +AG + +  P  A             AG   PG +  R  P
Sbjct: 561 ----QDGRPGPPGPPGARGQAGVMGFPGPKGA-------------AG--EPGKAGERGVP 601

Query: 180 LRPGAVRKS---------QPPGLRRQTAGGRARLGGARAVDPGTGWGHCACSRRRGERRS 230
             PGAV  +          PPG     AG R   G A +  PG   G    +   GE   
Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPG-PAGPAGERGEQGPAGS--PGF-QGLPGPAGPPGEAGK 657

Query: 231 RRAAGVPGELGAPG 244
               GVPG+LGAPG
Sbjct: 658 PGEQGVPGDLGAPG 671



 Score = 31.2 bits (69), Expect = 0.98
 Identities = 65/244 (26%), Positives = 78/244 (31%), Gaps = 27/244 (11%)

Query: 36   PQSPPPAG----PGAPGAPWRRGDEG----PGPAGGEAG--GPCGAAPGGCASGGCGVMG 85
            P +P P G     G  G P +RG+ G    PGP+ GE G  GP GA+      G  G  G
Sbjct: 946  PGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS-GEPGKQGPSGASGERGPPGPMGPPG 1004

Query: 86   VSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQW 145
            ++     S    +      P R  +  A   R          E  PA  P    A G   
Sbjct: 1005 LAGPPGESGREGAPGAEGSPGRDGSPGAKGDR---------GETGPAGPPGAPGAPGAPG 1055

Query: 146  E-RPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVRKSQPPGLRRQTAGGRARL 204
               PA     R         AGP  P   V  R P  P   R  +     +   G +   
Sbjct: 1056 PVGPAGKSGDR----GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111

Query: 205  GGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRG-- 262
            G +    P    G        G        G PG  GAPG      L      P  RG  
Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRT 1171

Query: 263  GDPG 266
            GD G
Sbjct: 1172 GDAG 1175



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 2/35 (5%)

Query: 38  SPPPAGPGAPGAPWRRGDEGPGPAGGEAG--GPCG 70
           S P   PG PGAP  +G +GP    GE G  GP G
Sbjct: 184 SGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMG 218



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 5/42 (11%)

Query: 32  GRAPPQSPP-PAGP----GAPGAPWRRGDEGPGPAGGEAGGP 68
           G    Q PP PAGP    GAPG    +GD G   A G  G P
Sbjct: 683 GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724



 Score = 30.4 bits (67), Expect = 1.7
 Identities = 24/56 (42%), Positives = 25/56 (44%), Gaps = 13/56 (23%)

Query: 33  RAPPQSPPPAG-------PGAPGAPWRRGDEG-PGPAGGE----AGGPCG-AAPGG 75
           R  P  P PAG       PGA G P  +G  G PG AG      A GP G   PGG
Sbjct: 370 RGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG 425



 Score = 30.0 bits (66), Expect = 2.2
 Identities = 19/45 (42%), Positives = 19/45 (42%), Gaps = 3/45 (6%)

Query: 34  APPQSPP---PAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGG 75
           AP Q  P   P   G PGAP   G  G   A G AG P    P G
Sbjct: 297 APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG 341



 Score = 29.6 bits (65), Expect = 2.9
 Identities = 64/257 (24%), Positives = 82/257 (31%), Gaps = 34/257 (13%)

Query: 35  PPQSPPPAGPGAPGAPWRRGDEG-PGPAG--GEAG-----------GPCGAAPGGCASGG 80
           P  + PP   G PG     GD G PGP+G  GE G           GP G      A G 
Sbjct: 646 PGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705

Query: 81  CGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCR-LRIFLRTASSELLPAIAPDGRR 139
            G  G +          +     +P    AA     +  R       ++  P    DG R
Sbjct: 706 DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSP--GKDGVR 763

Query: 140 --AGGLQWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVRKSQPPGLRRQ- 196
              G +    PA A   +       P+      G    R  P  PG    + PPG   Q 
Sbjct: 764 GLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823

Query: 197 -------TAGGRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTR 249
                   AG +   G      P    G        G + +R +AG PG  G PG     
Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPG----- 878

Query: 250 ALASTSRAPPRRGGDPG 266
             A+    PP   G+ G
Sbjct: 879 --AAGRVGPPGPSGNAG 893



 Score = 29.3 bits (64), Expect = 3.7
 Identities = 23/61 (37%), Positives = 25/61 (40%), Gaps = 12/61 (19%)

Query: 32  GRAPPQSP-----PPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGV 86
           G A PQ P     P    G PG P      GP  A G AG P GA     A G  G  G+
Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPP------GPAGAAGPAGNP-GADGQPGAKGANGAPGI 405

Query: 87  S 87
           +
Sbjct: 406 A 406



 Score = 28.9 bits (63), Expect = 4.9
 Identities = 19/59 (32%), Positives = 21/59 (35%), Gaps = 5/59 (8%)

Query: 32  GRAPPQSPP-----PAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMG 85
           G   P  PP     P  PG PG P   G  GP   GG             ++GG  V G
Sbjct: 121 GPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPG 179



 Score = 28.5 bits (62), Expect = 6.4
 Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 10/66 (15%)

Query: 30  RTGRAPPQSPP--------PAGPGAPGAPWRRGDEGPGPAGGEAG--GPCGAAPGGCASG 79
           + GR   + PP        P   G PG    RG  G   A G+AG  GP G       +G
Sbjct: 237 KPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG 296

Query: 80  GCGVMG 85
             G MG
Sbjct: 297 APGQMG 302



 Score = 28.1 bits (61), Expect = 8.3
 Identities = 17/45 (37%), Positives = 21/45 (46%), Gaps = 1/45 (2%)

Query: 32  GRAPPQSPPPAGP-GAPGAPWRRGDEGPGPAGGEAGGPCGAAPGG 75
           G + P    P+GP G PG P   G +G     GE G P  + P G
Sbjct: 174 GISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMG 218



 Score = 28.1 bits (61), Expect = 8.3
 Identities = 25/64 (39%), Positives = 28/64 (43%), Gaps = 14/64 (21%)

Query: 31   TGRAPPQSP--PPAGPGAPGAPWRRGDEGP-GPAG-----GEAG--GPCG----AAPGGC 76
            +G + P  P  PP   GAPG     G  GP GP G     G+AG  GP G      P G 
Sbjct: 1132 SGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191

Query: 77   ASGG 80
             S G
Sbjct: 1192 PSAG 1195


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 72/230 (31%), Positives = 88/230 (38%), Gaps = 56/230 (24%)

Query: 57  GPGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVP-ARSSAASACS 115
           GPGP G            GC +  CG    + ++S +F + SS  CR+  +R S     +
Sbjct: 5   GPGPGGSYP------ITFGCGARACGGRRANFSLSAAFRTCSSGTCRLTRSRKSRLERGT 58

Query: 116 CRLRIFLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLP---------SAG 166
                    A +E+  A  PD R        RPAA  R   PR    P         SA 
Sbjct: 59  FSPE---SAAGTEVSGAPHPDSR-------TRPAA--RPPHPRTRSPPGRSGSGTTFSAV 106

Query: 167 PPRPG--LSVRRRRPLRPG------AVRKSQPPGLRR---QTAGGRARLGGARAVDPGTG 215
           PPRP    S  R RP  PG      + R S  P   +   +TA GRA  GG+     G G
Sbjct: 107 PPRPSQHQSGSRLRPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQG 166

Query: 216 WGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGDP 265
                 S + G R S RA G P     P   C R      RA PRR   P
Sbjct: 167 ------SDQVGARPS-RAGGQP-----PPLTCRRC-----RAAPRRSARP 199


>gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo
           sapiens]
          Length = 209

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 72/230 (31%), Positives = 88/230 (38%), Gaps = 56/230 (24%)

Query: 57  GPGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVP-ARSSAASACS 115
           GPGP G            GC +  CG    + ++S +F + SS  CR+  +R S     +
Sbjct: 5   GPGPGGSYP------ITFGCGARACGGRRANFSLSAAFRTCSSGTCRLTRSRKSRLERGT 58

Query: 116 CRLRIFLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLP---------SAG 166
                    A +E+  A  PD R        RPAA  R   PR    P         SA 
Sbjct: 59  FSPE---SAAGTEVSGAPHPDSR-------TRPAA--RPPHPRTRSPPGRSGSGTTFSAV 106

Query: 167 PPRPG--LSVRRRRPLRPG------AVRKSQPPGLRR---QTAGGRARLGGARAVDPGTG 215
           PPRP    S  R RP  PG      + R S  P   +   +TA GRA  GG+     G G
Sbjct: 107 PPRPSQHQSGSRLRPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQG 166

Query: 216 WGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGDP 265
                 S + G R S RA G P     P   C R      RA PRR   P
Sbjct: 167 ------SDQVGARPS-RAGGQP-----PPLTCRRC-----RAAPRRSARP 199


>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
           sapiens]
          Length = 384

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 72/230 (31%), Positives = 88/230 (38%), Gaps = 56/230 (24%)

Query: 57  GPGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVP-ARSSAASACS 115
           GPGP G            GC +  CG    + ++S +F + SS  CR+  +R S     +
Sbjct: 5   GPGPGGSYP------ITFGCGARACGGRRANFSLSAAFRTCSSGTCRLTRSRKSRLERGT 58

Query: 116 CRLRIFLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLP---------SAG 166
                    A +E+  A  PD R        RPAA  R   PR    P         SA 
Sbjct: 59  FSPE---SAAGTEVSGAPHPDSR-------TRPAA--RPPHPRTRSPPGRSGSGTTFSAV 106

Query: 167 PPRPG--LSVRRRRPLRPG------AVRKSQPPGLRR---QTAGGRARLGGARAVDPGTG 215
           PPRP    S  R RP  PG      + R S  P   +   +TA GRA  GG+     G G
Sbjct: 107 PPRPSQHQSGSRLRPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQG 166

Query: 216 WGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGDP 265
                 S + G R S RA G P     P   C R      RA PRR   P
Sbjct: 167 ------SDQVGARPS-RAGGQP-----PPLTCRRC-----RAAPRRSARP 199


>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 72/230 (31%), Positives = 88/230 (38%), Gaps = 56/230 (24%)

Query: 57  GPGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLSFLSWSSSRCRVP-ARSSAASACS 115
           GPGP G            GC +  CG    + ++S +F + SS  CR+  +R S     +
Sbjct: 5   GPGPGGSYP------ITFGCGARACGGRRANFSLSAAFRTCSSGTCRLTRSRKSRLERGT 58

Query: 116 CRLRIFLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLSWLP---------SAG 166
                    A +E+  A  PD R        RPAA  R   PR    P         SA 
Sbjct: 59  FSPE---SAAGTEVSGAPHPDSR-------TRPAA--RPPHPRTRSPPGRSGSGTTFSAV 106

Query: 167 PPRPG--LSVRRRRPLRPG------AVRKSQPPGLRR---QTAGGRARLGGARAVDPGTG 215
           PPRP    S  R RP  PG      + R S  P   +   +TA GRA  GG+     G G
Sbjct: 107 PPRPSQHQSGSRLRPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQG 166

Query: 216 WGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPRRGGDP 265
                 S + G R S RA G P     P   C R      RA PRR   P
Sbjct: 167 ------SDQVGARPS-RAGGQP-----PPLTCRRC-----RAAPRRSARP 199


>gi|239755873 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 577

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 72/235 (30%), Positives = 93/235 (39%), Gaps = 46/235 (19%)

Query: 7   SQHHPFP----LGAFTLDQRDGKQRLRRT----GRAPPQSPPPAGPGAPGAPWRRGDEGP 58
           +Q HP P    L  F     D   R R++    G+    SPPPA  GAP  P +R + GP
Sbjct: 333 AQPHPRPGILMLKTFGCRGFDAAVRKRKSPALSGQWQSPSPPPALAGAPPTPQQRQNFGP 392

Query: 59  GPAG--GEAGGPCGAAPGGCASGGCG----VMGVSLTV--SLSFLSWSSSRCRVPARSSA 110
           G AG      GP GA  GGC  G  G    V G  L +  + S  SW +SR    AR   
Sbjct: 393 GCAGLSPRPEGPHGA--GGCPMGELGMSLRVWGTLLPLERARSLPSW-NSRGFCGARRGG 449

Query: 111 AS----------ACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRLPRLS 160
            S              +LR+    A  +   ++AP    + G    R  AA R   P+ S
Sbjct: 450 GSGRFLPGGGWRGARTKLRVCCTPAPGQSRGSLAPRPTGSAG----RALAAARLFAPQRS 505

Query: 161 --WLPS-AGPPRPGLSVRRRRPLRPGAVRKSQPPGLRRQTAGGRARLGGARAVDP 212
              LP+  G       +R  R L  GA           +TAG R++ G   A  P
Sbjct: 506 AAQLPARCGCFGSARGMRAPRRLLVGA----------EETAGARSKRGKVLAHSP 550


>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 1006

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 71/230 (30%), Positives = 86/230 (37%), Gaps = 35/230 (15%)

Query: 33  RAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSL 92
           R PP  P PA PG  G        G G A G  G  CG  P  C+ G   V G + + SL
Sbjct: 222 RPPPPRPSPA-PGLTG-------RGQGRARGAVGLDCGCRPRPCSFGQPDV-GSAPSRSL 272

Query: 93  SFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLP----AIAPDGRRAGGLQWERP 148
              S        P   S   +   R R F  T  SE  P       P    A   +W  P
Sbjct: 273 RGCSLRFRNTPPPIPGSDQPSSHGRPR-FRETGDSEDCPPFRAGTPPQQPTAPSSEWPGP 331

Query: 149 AAALRT------RLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVR-------KSQPPGLRR 195
             +  T       LPR + LP+    RPG S   +RP RPG V        K + P    
Sbjct: 332 QRSPGTGPRWTAPLPRPAPLPA---KRPGDSPASKRP-RPGGVSPEARDPPKGENPLCSS 387

Query: 196 QTAG--GRARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAP 243
           + AG  G  ++ G  A+  G   G     +  GE  S R A  P  LG P
Sbjct: 388 EAAGETGPTQVRGPDALGGGRLQGKGREGKAPGEGVSPRPA--PPRLGKP 435


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/68 (45%), Positives = 32/68 (47%), Gaps = 19/68 (27%)

Query: 31 TGRAPPQSPPPAG-------------PGAPGAPWRRGDE--GPGPAGGEAGGPCGAAPGG 75
          TG  PP  PPPAG             PG PGA  R G    G GP GG AGGP    PGG
Sbjct: 6  TGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGP-SQPPGG 64

Query: 76 CASGGCGV 83
             GG G+
Sbjct: 65 ---GGPGI 69



 Score = 30.0 bits (66), Expect = 2.2
 Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 2/48 (4%)

Query: 37  QSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVM 84
           +S PP  PG PG P   G  G G   G  G P G       +  CG++
Sbjct: 394 RSGPPGPPGGPGMP--PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLV 439



 Score = 28.5 bits (62), Expect = 6.4
 Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 9/80 (11%)

Query: 36  PQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAP--GGCASGGCGVMGVSLTVSLS 93
           P  P   GPG PG     G   PGP      GP GA P  GG         G   T    
Sbjct: 498 PLCPVGPGPGGPGPAGPMGPFNPGPFN---QGPPGAPPHAGGPPPHQYPPQGWGNT---- 550

Query: 94  FLSWSSSRCRVPARSSAASA 113
           +  W       P++++AA+A
Sbjct: 551 YPQWQPPAPHDPSKAAAAAA 570


>gi|223633890 hypothetical protein LOC729956 [Homo sapiens]
          Length = 538

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 37/114 (32%), Positives = 44/114 (38%), Gaps = 12/114 (10%)

Query: 38  SPPPAGPGAPGAPWRRGDEGPGPAG-------GEAGGPCGAAPGG-CASGGCGVMGVSLT 89
           +PPP   GA GA    G  GPG AG       G AGG  G  PGG  A   CGV+  +L 
Sbjct: 139 TPPPLAGGAGGAGGAGGGPGPGQAGWLEGGRTGGAGGRGGEGPGGSTAYVVCGVISFALA 198

Query: 90  VSLSFLSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGL 143
           V +      S   R P      +     + I    A     P   PD  R+  L
Sbjct: 199 VGVGAKVAFSKASRAPRAHRDINVPRALVDILRHQAG----PGTRPDRARSSSL 248


>gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo
           sapiens]
          Length = 304

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 62/218 (28%), Positives = 74/218 (33%), Gaps = 47/218 (21%)

Query: 27  RLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASG------- 79
           R +RT  + P      GP A  A  R G   P  AG  A GP  A  GG   G       
Sbjct: 50  RAKRTVLSSPSLG--GGPAAGSAILRAGSRSPRGAGPGAAGPRAAGRGGAGGGGRCCTRG 107

Query: 80  -----------------GCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFL 122
                            GC       + S ++  W   R R      A    S  L I +
Sbjct: 108 RGRFPCAGSGGRGARSRGCHSPSCCRSSSCAWHRWPQLRGR-----EAEPRASPALLICI 162

Query: 123 RTASSELLPAIAPDGRRA-GGLQWER-------PAAALRTRLPRLSWLPSAGPPRPGLSV 174
                  LPA    G RA  GL  +R          A R R  R S      PPRP    
Sbjct: 163 APRPRPALPAALHIGARATAGLAAKRAQPQLCSAGTAARGRRTRAS---PPTPPRPRPPG 219

Query: 175 RRRRPLRPGAVRKSQPPGLRRQTAGGRARLGGARAVDP 212
            R   +  G  R  +P G  R+ AGGR   GGA+ + P
Sbjct: 220 LRSGDVPRGGARVERPTG--RRGAGGR---GGAQRIPP 252


>gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo
           sapiens]
          Length = 304

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 62/218 (28%), Positives = 74/218 (33%), Gaps = 47/218 (21%)

Query: 27  RLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASG------- 79
           R +RT  + P      GP A  A  R G   P  AG  A GP  A  GG   G       
Sbjct: 50  RAKRTVLSSPSLG--GGPAAGSAILRAGSRSPRGAGPGAAGPRAAGRGGAGGGGRCCTRG 107

Query: 80  -----------------GCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFL 122
                            GC       + S ++  W   R R      A    S  L I +
Sbjct: 108 RGRFPCAGSGGRGARSRGCHSPSCCRSSSCAWHRWPQLRGR-----EAEPRASPALLICI 162

Query: 123 RTASSELLPAIAPDGRRA-GGLQWER-------PAAALRTRLPRLSWLPSAGPPRPGLSV 174
                  LPA    G RA  GL  +R          A R R  R S      PPRP    
Sbjct: 163 APRPRPALPAALHIGARATAGLAAKRAQPQLCSAGTAARGRRTRAS---PPTPPRPRPPG 219

Query: 175 RRRRPLRPGAVRKSQPPGLRRQTAGGRARLGGARAVDP 212
            R   +  G  R  +P G  R+ AGGR   GGA+ + P
Sbjct: 220 LRSGDVPRGGARVERPTG--RRGAGGR---GGAQRIPP 252


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 64/251 (25%), Positives = 87/251 (34%), Gaps = 43/251 (17%)

Query: 3   LPEPSQHHPFPLG-AFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPA 61
           LP P   HP+    AF L  +     L   G   P+  P  G G  GA    G  GPG +
Sbjct: 344 LPPPLFPHPYGFPTAFGLCPKKDDPVL---GAGEPKGGPGTGSGGGGAGTGGGAGGPGAS 400

Query: 62  ---GGEAGGPCGAA------PGGCASGGCGVMGVSLTV--------------SLSFLSWS 98
               G   GP G A      P G A     V   +                 SL   S+ 
Sbjct: 401 HLPPGAGAGPGGGAMFWGHQPSGAAKDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYP 460

Query: 99  SSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQWERPAAALRTRL-- 156
           +++ +  A ++A +A +        + + E L    P      G +   P+A  R  L  
Sbjct: 461 AAQSQAKAVAAAVAAAAAAAAAAAGSGAPEPLDGAEPAKESGLGAEERCPSALSRGPLDE 520

Query: 157 --------PRLSWLPSAGPP--RPGLSVRRRRPLRPGAVRKSQPPGLRRQTAGGRARLGG 206
                   P L+ LP   PP  R G  V   RP+       ++  G  R+  G     G 
Sbjct: 521 DGTDEALPPPLAPLPPPPPPPARKGSYVSAFRPVVKDTESIAKLYGSAREAYGA----GP 576

Query: 207 ARAVDPGTGWG 217
           AR   PG G G
Sbjct: 577 ARGPGPGAGSG 587


>gi|239756517 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 316

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 62/218 (28%), Positives = 74/218 (33%), Gaps = 47/218 (21%)

Query: 27  RLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASG------- 79
           R +RT  + P      GP A  A  R G   P  AG  A GP  A  GG   G       
Sbjct: 50  RAKRTVLSSPSLG--GGPAAGSAILRAGSRSPRGAGPGAAGPRAAGRGGAGGGGRCCTRG 107

Query: 80  -----------------GCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRLRIFL 122
                            GC       + S ++  W   R R      A    S  L I +
Sbjct: 108 RGRFPCAGSGGRGARSRGCHSPSCCRSSSCAWHRWPQLRGR-----EADPRASPALLICI 162

Query: 123 RTASSELLPAIAPDGRRA-GGLQWER-------PAAALRTRLPRLSWLPSAGPPRPGLSV 174
                  LPA    G RA  GL  +R          A R R  R S      PPRP    
Sbjct: 163 APRPRPALPAALHIGARATAGLAAKRAQPQLCSAGTAARGRRTRAS---PPTPPRPRPPG 219

Query: 175 RRRRPLRPGAVRKSQPPGLRRQTAGGRARLGGARAVDP 212
            R   +  G  R  +P G  R+ AGGR   GGA+ + P
Sbjct: 220 LRSGDVPRGGARVERPTG--RRGAGGR---GGAQRIPP 252


>gi|239755333 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 267

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 5/110 (4%)

Query: 37  QSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGG-CGVMGVSLTVSLSFL 95
           Q   P+G  APGAP   G E     GG   G  G A  G A GG   + G    ++LS  
Sbjct: 151 QGQLPSGFAAPGAPAWSGSEDTA-TGGCPRGEAGTALAGLAMGGTASLTGRGCWINLSHA 209

Query: 96  SWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPDGRRAGGLQW 145
           +  S+    PA      +CS R R   + A S   P  +  G  + G  W
Sbjct: 210 APYSAPAHPPA---GTRSCSPRKRPVAKAAPSAAEPRASAAGTESRGTGW 256


>gi|56606142 complement component 1, q subcomponent-like 4 [Homo
          sapiens]
          Length = 238

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 25/57 (43%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 6  PSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAG 62
          P+   PFP GA     R GK  LR     P    PP  PG PG P   G  GPGP G
Sbjct: 46 PASVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPP---GPPGPGPGG 99



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 24/54 (44%), Positives = 24/54 (44%), Gaps = 9/54 (16%)

Query: 36 PQSPPPAGPGAPGAPWRRGDEG-------PGPAG--GEAGGPCGAAPGGCASGG 80
          P S PP  PGA G   RRG  G       PGP G  GE G P    P G   GG
Sbjct: 46 PASVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPGPGPGG 99



 Score = 32.3 bits (72), Expect = 0.44
 Identities = 26/65 (40%), Positives = 27/65 (41%), Gaps = 23/65 (35%)

Query: 36  PQSPPPAG---------PGAPGAPWRRGDEG----PGPAG-----GEAG-----GPCGAA 72
           P+ P P G         PGA G   RRG  G    PGP G     GE G     GP G  
Sbjct: 37  PRGPGPDGAPASVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPGPG 96

Query: 73  PGGCA 77
           PGG A
Sbjct: 97  PGGVA 101


>gi|5032105 small optic lobes [Homo sapiens]
          Length = 1086

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 72/257 (28%), Positives = 87/257 (33%), Gaps = 66/257 (25%)

Query: 4   PEPSQHHPFPLGAFTLDQRDGKQRLRRTGRAPPQSPPP---AGPGAPGAPWRRGDEGPGP 60
           PEP +  PF   + TL Q +   R RR    PPQ  PP   A   +P A  R   +G G 
Sbjct: 224 PEPPRVPPFSPFSSTL-QNNPVPRSRR--EVPPQLQPPVPEAAQPSPSAGCRGAPQGSGW 280

Query: 61  AGGE-------------------AGGPCGAAPGGCASGGCGVMGVSLTV--------SLS 93
           AG                      GG      G   SG   +     TV        S  
Sbjct: 281 AGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPD 340

Query: 94  FLSWSSSRC--RVPARSSAASACSC-RLRIFLRTASSELLPAIAPD---------GRRAG 141
           F +WS ++C  R P  +   SAC C +L  F         P   PD         GR  G
Sbjct: 341 FTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEP---PTHCPDCGADKPSPCGRSCG 397

Query: 142 GL---------------QWERPAAALRTRLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVR 186
            +               QW  PA  L   L  L     A    P L V +RR   P   R
Sbjct: 398 RVSSAQKAARVLPERPGQWACPACTL---LNALRAKHCAACHTPQLLVAQRRGAAPLRRR 454

Query: 187 KSQPPGLRRQTAGGRAR 203
           +S     RRQT  G A+
Sbjct: 455 ESMHVEQRRQTDEGEAK 471


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 79/270 (29%), Positives = 89/270 (32%), Gaps = 48/270 (17%)

Query: 29  RRTGRAPPQSPPPAGPGAPGAPWRRGDEG--PGPAGGEAGGPCGAAPGGCASGG------ 80
           RR GR P      +   APGAP  RG  G  PGP    A    G  P   A         
Sbjct: 83  RRLGRVPLTFREASPGPAPGAPRARGSCGREPGPRRRRAPSSAGKRPAAAARAAPPRQRS 142

Query: 81  ---CGVMGVSLTVSLSF-LSWSSSRCRVPARSSAASACSCRLRIFLRTASSELLPAIAPD 136
              C    V   V  S   S     CR   R      C CR R          LP   P 
Sbjct: 143 LARCLPRSVGSCVRPSVGPSLPRRHCRRHCR------CHCRRR---------PLPKPPPL 187

Query: 137 GRRAGGLQWERPAAALR-TRLPRLSWLPSAGPPRPGLS-VRRRRPLRPGAVRKSQPPGLR 194
             R G     R AA L  +R P LS  P     R   S      PL     R  +  G R
Sbjct: 188 QPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGAR 247

Query: 195 RQTAGGRARLGGAR----AVDPGTGWGHCACSR---RRGERRSRRAAGVPGEL------- 240
           R+  G   R+ G R       P    G  A  R   RR  R+ R+  G PG         
Sbjct: 248 RRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGVSPREGAQG 307

Query: 241 -GAPGGHCTRALASTSRAPPR----RGGDP 265
            G  GG   RA  S++   P     +GG P
Sbjct: 308 EGVRGGVTPRARGSSTCLRPSPATWQGGAP 337



 Score = 30.4 bits (67), Expect = 1.7
 Identities = 41/146 (28%), Positives = 61/146 (41%), Gaps = 23/146 (15%)

Query: 21  QRDGKQRL---RRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCA 77
           +R G++R    RR G A    P PAGP A   P R G+        + GG  G +P   A
Sbjct: 249 RRGGEERRVRGRRQGCALGSPPIPAGPAA---PGRAGERRAARQWRKRGGGPGVSPREGA 305

Query: 78  SGGCGVMGVSLTVSLSFLSWSSSRCRVPARSSAASACSCRL------RIFLRTASSELLP 131
            G  GV G      ++  +  SS C  P+ ++       R       R+   +A +E +P
Sbjct: 306 QGE-GVRG-----GVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVP 359

Query: 132 AIAPDGRRAGGLQWERPAAALRTRLP 157
                G  A    +E P ++ RT+ P
Sbjct: 360 G----GHTASNPTYE-PLSSRRTKAP 380


>gi|239743072 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 837

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 63/213 (29%)

Query: 36  PQSPPPAGPGAPGAPWRRGDEGPGPA-------GGEAGGPCGAAPGGCASGGCGVMGVSL 88
           P S   AGPG      R G +  GP        G   GGP G A GG +  G G  G   
Sbjct: 583 PASLALAGPGIA----RLGCDLDGPRALVEGLHGRHEGGPLGGAGGGGSGEGQG-RGPGS 637

Query: 89  TVSLSFLSWSSSRCRV-----PARSSAASACSCRLRIFLRTASSELLPAIAPDG------ 137
            VS+   S + S CR      P  +SA SA S        T+ +  L  ++ DG      
Sbjct: 638 RVSVRRSSRAPSSCRAASLAPPRPASATSAGS-------PTSPAPPLHMVSTDGCSAAFL 690

Query: 138 -------------RRAGGLQWERPAAA--LRTRLP----------RLSWLPSAG---PPR 169
                        RR G   W   A A  +R+  P          R S+LP +G   PPR
Sbjct: 691 VLDSARKGDRRSARRGGPRSWRPSARASWVRSTTPRGPEASSPRARGSFLPKSGGGSPPR 750

Query: 170 PGLSV----RRRRPLRPGAVRKSQPPGLRRQTA 198
           P  S+    R   PL  GA  +  PPGL  + A
Sbjct: 751 PARSLAGPSRDDEPL-AGAPEEWPPPGLSSRRA 782


>gi|239508718 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 837

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 65/213 (30%), Positives = 81/213 (38%), Gaps = 63/213 (29%)

Query: 36  PQSPPPAGPGAPGAPWRRGDEGPGPA-------GGEAGGPCGAAPGGCASGGCGVMGVSL 88
           P S   AGPG      R G +  GP        G   GGP G A GG +  G G  G   
Sbjct: 583 PASLALAGPGIA----RLGCDLDGPRALVEGLHGRHEGGPLGGAGGGGSGEGQG-RGPGS 637

Query: 89  TVSLSFLSWSSSRCRV-----PARSSAASACSCRLRIFLRTASSELLPAIAPDG------ 137
            VS+   S + S CR      P  +SA SA S        T+ +  L  ++ DG      
Sbjct: 638 RVSVRRSSRAPSSCRAASLAPPRPASATSAGS-------PTSPAPPLHMVSTDGCSAAFL 690

Query: 138 -------------RRAGGLQWERPAAA--LRTRLP----------RLSWLPSAG---PPR 169
                        RR G   W   A A  +R+  P          R S+LP +G   PPR
Sbjct: 691 VLDSARKGDRRSARRGGPRSWRPSARASWVRSTTPRGPEASSPRARGSFLPKSGGGSPPR 750

Query: 170 PGLSV----RRRRPLRPGAVRKSQPPGLRRQTA 198
           P  S+    R   PL  GA  +  PPGL  + A
Sbjct: 751 PARSLAGPSRDDEPL-AGAPEEWPPPGLSSRRA 782


>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
            containing 2 [Homo sapiens]
          Length = 1455

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 42/126 (33%), Positives = 50/126 (39%), Gaps = 22/126 (17%)

Query: 142  GLQWERPAAALRTRLPRLSWLPSA-GPPRPGLSVRRRRPLRPGAVRKSQPPGLRRQTAGG 200
            G Q ER A+  R   PRL   P   G P  G         RP +  +++ PGL    A  
Sbjct: 1311 GEQRERSASPQRAARPRLEEAPGGQGRPEAG---------RPAS--EARAPGLAAADAAD 1359

Query: 201  RARLGGARAVDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGGHCTRALASTSRAPPR 260
             AR GG  A     G   C   RR G   +   AG       PGG  + AL +  RA  R
Sbjct: 1360 AARAGGKEAPRAAAGSELC---RREGPGAAPAFAG-------PGGGGSGALEAEGRAGAR 1409

Query: 261  RGGDPG 266
             G  PG
Sbjct: 1410 AGPRPG 1415



 Score = 28.5 bits (62), Expect = 6.4
 Identities = 21/57 (36%), Positives = 23/57 (40%), Gaps = 9/57 (15%)

Query: 24   GKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGG 80
            G +  RR G  P  +P  AGPG        G  G   A G AG   G  PG    GG
Sbjct: 1374 GSELCRREG--PGAAPAFAGPGG-------GGSGALEAEGRAGARAGPRPGPRPPGG 1421


>gi|24497460 Shaw-related voltage-gated potassium channel protein
          3 [Homo sapiens]
          Length = 757

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 20/58 (34%), Positives = 26/58 (44%)

Query: 24 GKQRLRRTGRAPPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGC 81
          G+Q   +   APP  PP + P  P  P ++    PGPA   AG P    PG   +  C
Sbjct: 12 GRQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPC 69



 Score = 29.3 bits (64), Expect = 3.7
 Identities = 18/52 (34%), Positives = 19/52 (36%)

Query: 35 PPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGV 86
          P Q  P A P  P AP   GD    P  G      G   GG    G  V+ V
Sbjct: 43 PAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINV 94


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 23/54 (42%), Positives = 25/54 (46%), Gaps = 6/54 (11%)

Query: 34  APPQSPPPAGPGAPGAPWRRGDEGPGPAGGEAGGPC-----GAAPGGCASGGCG 82
           A PQ PPP  P  P     +GD   G AGG  G PC     G+ P G A G  G
Sbjct: 191 AGPQPPPPPAPPQPEGAADKGDPRTG-AGGGGGSPCTKATPGSEPKGAAEGSGG 243


>gi|239753335 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 113

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 27/65 (41%), Positives = 30/65 (46%), Gaps = 9/65 (13%)

Query: 29 RRTGRAPP--QSPPPAGPGAPG---APWRRGDEGP-GPAGGEAGG---PCGAAPGGCASG 79
          R + R PP  Q P PA P  P    A W R   GP   +GG+ GG     GA PGG   G
Sbjct: 34 RGSWRRPPRRQRPGPAAPSPPARGAAAWGRSGGGPAAQSGGDGGGLPRRAGAEPGGRGGG 93

Query: 80 GCGVM 84
            G M
Sbjct: 94 SGGTM 98



 Score = 31.2 bits (69), Expect = 0.98
 Identities = 32/96 (33%), Positives = 35/96 (36%), Gaps = 6/96 (6%)

Query: 150 AALRTRLPRLSWLPSAGPPRPGLSVRRRRPLRPGAVRKSQPPGLRRQTAGGRARLGGARA 209
           A  R R P       A  P PG    RR P R      +  P  R   A GR+  GG  A
Sbjct: 12  AGERARAPSGGGSGQAQRPGPGRGSWRRPPRRQRPGPAAPSPPARGAAAWGRSG-GGPAA 70

Query: 210 VDPGTGWGHCACSRRRGERRSRRAAGVPGELGAPGG 245
              G G G     RR G     R  G  G +  PGG
Sbjct: 71  QSGGDGGG---LPRRAGAEPGGRGGGSGGTM--PGG 101


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,073,989
Number of Sequences: 37866
Number of extensions: 1127556
Number of successful extensions: 21081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 360
Number of HSP's successfully gapped in prelim test: 869
Number of HSP's that attempted gapping in prelim test: 9956
Number of HSP's gapped (non-prelim): 8853
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.