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Search of human proteins with 111125011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
(379 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens] 832 0.0
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 182 3e-46
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 129 4e-30
gi|153946395 tenascin C precursor [Homo sapiens] 128 7e-30
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 126 4e-29
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 122 7e-28
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 120 2e-27
gi|122937283 6720455I24Rik homolog [Homo sapiens] 112 7e-25
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 111 9e-25
gi|4557679 jagged 1 precursor [Homo sapiens] 110 2e-24
gi|148833508 notch1 preproprotein [Homo sapiens] 109 4e-24
gi|157384973 tenascin R [Homo sapiens] 109 4e-24
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 108 6e-24
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 108 8e-24
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 108 8e-24
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 108 8e-24
gi|110735443 delta-like 1 [Homo sapiens] 107 1e-23
gi|148886654 polydom [Homo sapiens] 107 1e-23
gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens] 107 2e-23
gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens] 107 2e-23
gi|74136023 delta-like 1 homolog [Homo sapiens] 106 3e-23
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 106 3e-23
gi|93102379 low density lipoprotein-related protein 1B precursor... 105 7e-23
gi|134244285 Notch homolog 3 [Homo sapiens] 100 3e-21
gi|24041035 notch 2 preproprotein [Homo sapiens] 99 5e-21
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 99 6e-21
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 99 6e-21
gi|45593147 EGF-like-domain, multiple 9 [Homo sapiens] 99 8e-21
gi|45545431 EGF-like-domain, multiple 9 [Homo sapiens] 99 8e-21
gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 98 1e-20
>gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
Length = 379
Score = 832 bits (2149), Expect = 0.0
Identities = 379/379 (100%), Positives = 379/379 (100%)
Query: 1 MARRSAFPAAALWLWSILLCLLALRAEAGPPQEESLYLWIDAHQARVLIGFEEDILIVSE 60
MARRSAFPAAALWLWSILLCLLALRAEAGPPQEESLYLWIDAHQARVLIGFEEDILIVSE
Sbjct: 1 MARRSAFPAAALWLWSILLCLLALRAEAGPPQEESLYLWIDAHQARVLIGFEEDILIVSE 60
Query: 61 GKMAPFTHDFRKAQQRMPAIPVNIHSMNFTWQAAGQAEYFYEFLSLRSLDKGIMADPTVN 120
GKMAPFTHDFRKAQQRMPAIPVNIHSMNFTWQAAGQAEYFYEFLSLRSLDKGIMADPTVN
Sbjct: 61 GKMAPFTHDFRKAQQRMPAIPVNIHSMNFTWQAAGQAEYFYEFLSLRSLDKGIMADPTVN 120
Query: 121 VPLLGTVPHKASVVQVGFPCLGKQDGVAAFEVDVIVMNSEGNTILQTPQNAIFFKTCQQA 180
VPLLGTVPHKASVVQVGFPCLGKQDGVAAFEVDVIVMNSEGNTILQTPQNAIFFKTCQQA
Sbjct: 121 VPLLGTVPHKASVVQVGFPCLGKQDGVAAFEVDVIVMNSEGNTILQTPQNAIFFKTCQQA 180
Query: 181 ECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN 240
ECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN
Sbjct: 181 ECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN 240
Query: 241 CDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGY 300
CDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGY
Sbjct: 241 CDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGY 300
Query: 301 QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYEASLIHALRPAGAQLRQHT 360
QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYEASLIHALRPAGAQLRQHT
Sbjct: 301 QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYEASLIHALRPAGAQLRQHT 360
Query: 361 PSLKKAEERRDPPESNYIW 379
PSLKKAEERRDPPESNYIW
Sbjct: 361 PSLKKAEERRDPPESNYIW 379
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 182 bits (463), Expect = 3e-46
Identities = 72/163 (44%), Positives = 91/163 (55%)
Query: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPG 235
TC + C C++GG C +C CP GF GP CE +C C NGG C+TP C C PG
Sbjct: 1356 TCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPG 1415
Query: 236 FYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCK 295
+YG C A C C NGG+C P C+CP G GE C+ + C PC+NGG C+ + C
Sbjct: 1416 WYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCV 1475
Query: 296 CSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCN 338
C +GY G K +C+P C G C P+ C C GW G+ CN
Sbjct: 1476 CREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCN 1518
Score = 171 bits (433), Expect = 1e-42
Identities = 71/167 (42%), Positives = 89/167 (53%)
Query: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPG 235
TC A C C NGG CN+ C CP+GF G HC+ A C P C NGG C+ C+C G
Sbjct: 1420 TCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREG 1479
Query: 236 FYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCK 295
+ G K+ C TC NGG C P C CP G G++C C Q C+NGG+CI S C
Sbjct: 1480 YTGRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICH 1539
Query: 296 CSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYE 342
C ++G C P+C P C G C PN C C+ + G C K+ +
Sbjct: 1540 CPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCEKKIQ 1586
Score = 157 bits (397), Expect = 1e-38
Identities = 63/160 (39%), Positives = 85/160 (53%)
Query: 182 CPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNC 241
C C C IC+C G+ G +C+ ALC P C N G C+ P C C PG G C
Sbjct: 1298 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 1357
Query: 242 DKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQ 301
D+ +C+ C +GGTC C CP G G +CE C + C NGG+C+ C+C G+
Sbjct: 1358 DEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWY 1417
Query: 302 GDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRY 341
G CS +C+P C G+C++PN C C G+ G HC +
Sbjct: 1418 GPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAF 1457
Score = 137 bits (344), Expect = 2e-32
Identities = 58/140 (41%), Positives = 73/140 (52%)
Query: 170 NAIFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGF 229
N F + CQ A C C+NGG C +C C +G+ G +K++C P CMNGG CV P
Sbjct: 1446 NGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPST 1505
Query: 230 CICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCI 289
C CP G+ G C+ C C NGG C P C CP EG +C+I C C GG+CI
Sbjct: 1506 CSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCI 1565
Query: 290 GKSKCKCSKGYQGDLCSKPV 309
+ C C Y G C K +
Sbjct: 1566 FPNVCSCRTEYSGVKCEKKI 1585
Score = 117 bits (292), Expect = 2e-26
Identities = 49/126 (38%), Positives = 61/126 (48%)
Query: 213 LCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQ 272
+C C CV P C C PG+ G NC A C C N G C P C C PG G
Sbjct: 1297 ICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGAT 1356
Query: 273 CEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGW 332
C+ C PC++GG C+ + C C G+ G C VC C G C P+ CQC+ GW
Sbjct: 1357 CDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGW 1416
Query: 333 HGRHCN 338
+G C+
Sbjct: 1417 YGPTCS 1422
Score = 82.8 bits (203), Expect = 5e-16
Identities = 58/207 (28%), Positives = 72/207 (34%), Gaps = 55/207 (26%)
Query: 186 CRNGGFCNERR---------ICECPDGFHGPHCEKALCTPRCMNGGL-CVTPGF----CI 231
C NGG C R +C C GFHG CE + + GL GF C
Sbjct: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCD 1242
Query: 232 CPPGF---------------------YGVNCDKAN--------------------CSTTC 250
CPP VN ++ + C C
Sbjct: 1243 CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPC 1302
Query: 251 FNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVC 310
C P C C PG G C+ + C C+N GKCI + C+C G+ G C + C
Sbjct: 1303 GKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHC 1362
Query: 311 EPGCGAHGTCHEPNKCQCQEGWHGRHC 337
P C GTC N C C G+ G C
Sbjct: 1363 NPPCQHGGTCLAGNLCTCPYGFVGPRC 1389
Score = 82.8 bits (203), Expect = 5e-16
Identities = 52/179 (29%), Positives = 72/179 (40%), Gaps = 55/179 (30%)
Query: 218 CMNGGLCVT-----PG----FCICPPGFYGVNC--DKANC-STTCFNGG--TCFYPGKCI 263
C+NGG CV+ PG C+C PGF+G C D + C S C G + F+ C
Sbjct: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCD 1242
Query: 264 CPPGLEGEQCEISK-----------------------------------------CPQPC 282
CPP L+ E +++ C PC
Sbjct: 1243 CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPC 1302
Query: 283 RNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRY 341
+C+ + CKC GY G C +C+P C HG C +PN CQC G G C++ +
Sbjct: 1303 GKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEH 1361
Score = 42.7 bits (99), Expect = 5e-04
Identities = 41/146 (28%), Positives = 49/146 (33%), Gaps = 55/146 (37%)
Query: 247 STTCFNGGTC-----FYPGK----CICPPGLEGEQCE--ISKC-PQPCRNGGKCIG--KS 292
S C NGG+C F PG C+C PG G CE IS C PC G G
Sbjct: 1180 SCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSY 1239
Query: 293 KCKC---------------------------------SKGYQG-DLCSKP-------VCE 311
C C K QG KP +C+
Sbjct: 1240 SCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICK 1299
Query: 312 PGCGAHGTCHEPNKCQCQEGWHGRHC 337
CG C PN C+C+ G+ G +C
Sbjct: 1300 YPCGKSRECVAPNICKCKPGYIGSNC 1325
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 129 bits (324), Expect = 4e-30
Identities = 63/157 (40%), Positives = 83/157 (52%), Gaps = 10/157 (6%)
Query: 186 CRNGGFCNERRICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFYGVNCD-- 242
C G C + C C G+ G HCE+ C P C + G+CV G C+C PG+ G+NC+
Sbjct: 645 CGGHGSCIDGN-CVCSAGYKGEHCEEVDCLDPTCSSHGVCVN-GECLCSPGWGGLNCELA 702
Query: 243 KANCSTTCFNGGTCFYP--GKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGY 300
+ C C GT + P G C C P G C + C C G CIG C+C +G+
Sbjct: 703 RVQCPDQCSGHGT-YLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG-GACRCEEGW 760
Query: 301 QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337
G C + VC P C HGTC + KC+C+EGW+G HC
Sbjct: 761 TGAACDQRVCHPRCIEHGTCKD-GKCECREGWNGEHC 796
Score = 94.4 bits (233), Expect = 2e-19
Identities = 49/128 (38%), Positives = 65/128 (50%), Gaps = 8/128 (6%)
Query: 214 CTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQC 273
C C G CV+ G C C PGF G +C KA C C G + G C C G +G +C
Sbjct: 576 CPRNCHGNGECVS-GVCHCFPGFLGADCAKAACPVLCSGNGQ-YSKGTCQCYSGWKGAEC 633
Query: 274 EI--SKCPQP-CRNGGKCIGKSKCKCSKGYQGDLCSKPVC-EPGCGAHGTCHEPNKCQCQ 329
++ ++C P C G CI C CS GY+G+ C + C +P C +HG C +C C
Sbjct: 634 DVPMNQCIDPSCGGHGSCI-DGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVN-GECLCS 691
Query: 330 EGWHGRHC 337
GW G +C
Sbjct: 692 PGWGGLNC 699
Score = 93.6 bits (231), Expect = 3e-19
Identities = 45/132 (34%), Positives = 66/132 (50%), Gaps = 6/132 (4%)
Query: 179 QAECPGGCR-NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFY 237
+ +CP C +G + + +C C + GP C +C+ C G+C+ G C C G+
Sbjct: 703 RVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG-GACRCEEGWT 761
Query: 238 GVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKC-IGKS--KC 294
G CD+ C C GTC GKC C G GE C I CP C G+C +G++ +C
Sbjct: 762 GAACDQRVCHPRCIEHGTC-KDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQC 820
Query: 295 KCSKGYQGDLCS 306
C G++G C+
Sbjct: 821 VCQTGWRGPGCN 832
Score = 52.4 bits (124), Expect = 7e-07
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 275 ISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHG 334
+ CP+ C G+C+ C C G+ G C+K C C +G + CQC GW G
Sbjct: 573 VQDCPRNCHGNGECV-SGVCHCFPGFLGADCAKAACPVLCSGNGQ-YSKGTCQCYSGWKG 630
Query: 335 RHCN 338
C+
Sbjct: 631 AECD 634
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 128 bits (322), Expect = 7e-30
Identities = 60/165 (36%), Positives = 82/165 (49%), Gaps = 6/165 (3%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNG-GLCVTPGFCICPPG 235
C Q CP C + G C +C C +G+ G C + +C C G CV G C+C G
Sbjct: 216 CSQLACPSDCNDQGKC-VNGVCICFEGYAGADCSREICPVPCSEEHGTCVD-GLCVCHDG 273
Query: 236 FYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCK 295
F G +C+K C C+N G C +C+C G GE C CP C + G+CI C
Sbjct: 274 FAGDDCNKPLCLNNCYNRGRC-VENECVCDEGFTGEDCSELICPNDCFDRGRCI-NGTCY 331
Query: 296 CSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
C +G+ G+ C KP C C G C E +C C EG+ G C+++
Sbjct: 332 CEEGFTGEDCGKPTCPHACHTQGRCEE-GQCVCDEGFAGVDCSEK 375
Score = 128 bits (322), Expect = 7e-30
Identities = 58/163 (35%), Positives = 78/163 (47%), Gaps = 5/163 (3%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C + C C N G C E C C +GF G C + +C C + G C+ G C C GF
Sbjct: 279 CNKPLCLNNCYNRGRCVENE-CVCDEGFTGEDCSELICPNDCFDRGRCIN-GTCYCEEGF 336
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
G +C K C C G C G+C+C G G C +CP C N G+C+ +C+C
Sbjct: 337 TGEDCGKPTCPHACHTQGRC-EEGQCVCDEGFAGVDCSEKRCPADCHNRGRCV-DGRCEC 394
Query: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
G+ G C + C GC HG C +C C EG+ G C++
Sbjct: 395 DDGFTGADCGELKCPNGCSGHGRCVN-GQCVCDEGYTGEDCSQ 436
Score = 126 bits (316), Expect = 4e-29
Identities = 60/164 (36%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C + CP C G C E + C C +GF G C + C C N G CV G C C GF
Sbjct: 341 CGKPTCPHACHTQGRCEEGQ-CVCDEGFAGVDCSEKRCPADCHNRGRCVD-GRCECDDGF 398
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
G +C + C C G C G+C+C G GE C +CP C + G+C+ + KC C
Sbjct: 399 TGADCGELKCPNGCSGHGRCVN-GQCVCDEGYTGEDCSQLRCPNDCHSRGRCV-EGKCVC 456
Query: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
+G++G CS C C HG C C C +G+ G C R
Sbjct: 457 EQGFKGYDCSDMSCPNDCHQHGRCVN-GMCVCDDGYTGEDCRDR 499
Score = 121 bits (303), Expect = 1e-27
Identities = 56/164 (34%), Positives = 79/164 (48%), Gaps = 5/164 (3%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C + +CP GC G C + C C +G+ G C + C C + G CV G C+C GF
Sbjct: 403 CGELKCPNGCSGHGRCVNGQ-CVCDEGYTGEDCSQLRCPNDCHSRGRCVE-GKCVCEQGF 460
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
G +C +C C G C G C+C G GE C +CP+ C N G C+ +C C
Sbjct: 461 KGYDCSDMSCPNDCHQHGRCVN-GMCVCDDGYTGEDCRDRQCPRDCSNRGLCV-DGQCVC 518
Query: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
G+ G C++ C C G C +C C EG+ G+ C ++
Sbjct: 519 EDGFTGPDCAELSCPNDCHGQGRCVN-GQCVCHEGFMGKDCKEQ 561
Score = 121 bits (303), Expect = 1e-27
Identities = 56/163 (34%), Positives = 77/163 (47%), Gaps = 5/163 (3%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C CP C G C +C C DG+ G C C C N GLCV G C+C GF
Sbjct: 465 CSDMSCPNDCHQHGRC-VNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD-GQCVCEDGF 522
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
G +C + +C C G C G+C+C G G+ C+ +CP C G+C+ +C C
Sbjct: 523 TGPDCAELSCPNDCHGQGRCVN-GQCVCHEGFMGKDCKEQRCPSDCHGQGRCV-DGQCIC 580
Query: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
+G+ G C + C C G C +C C EG+ G C++
Sbjct: 581 HEGFTGLDCGQHSCPSDCNNLGQC-VSGRCICNEGYSGEDCSE 622
Score = 112 bits (280), Expect = 5e-25
Identities = 58/152 (38%), Positives = 74/152 (48%), Gaps = 5/152 (3%)
Query: 189 GGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCST 248
G F E C C G+ GP+C + C C G C+ G CIC GF G +C + C +
Sbjct: 165 GNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCI-DGQCICDDGFTGEDCSQLACPS 223
Query: 249 TCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPC-RNGGKCIGKSKCKCSKGYQGDLCSK 307
C + G C G CIC G G C CP PC G C+ C C G+ GD C+K
Sbjct: 224 DCNDQGKC-VNGVCICFEGYAGADCSREICPVPCSEEHGTCV-DGLCVCHDGFAGDDCNK 281
Query: 308 PVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
P+C C G C E N+C C EG+ G C++
Sbjct: 282 PLCLNNCYNRGRCVE-NECVCDEGFTGEDCSE 312
Score = 99.4 bits (246), Expect = 5e-21
Identities = 50/126 (39%), Positives = 62/126 (49%), Gaps = 5/126 (3%)
Query: 216 PRCMNGGLCVTPGF-CICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCE 274
P C G T G C+C PG+ G NC + C C G C G+CIC G GE C
Sbjct: 159 PFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCI-DGQCICDDGFTGEDCS 217
Query: 275 ISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCG-AHGTCHEPNKCQCQEGWH 333
CP C + GKC+ C C +GY G CS+ +C C HGTC + C C +G+
Sbjct: 218 QLACPSDCNDQGKCV-NGVCICFEGYAGADCSREICPVPCSEEHGTCVD-GLCVCHDGFA 275
Query: 334 GRHCNK 339
G CNK
Sbjct: 276 GDDCNK 281
Score = 55.1 bits (131), Expect = 1e-07
Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
Query: 175 KTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPP 234
K C++ CP C G C + + C C +GF G C + C C N G CV+ G CIC
Sbjct: 556 KDCKEQRCPSDCHGQGRCVDGQ-CICHEGFTGLDCGQHSCPSDCNNLGQCVS-GRCICNE 613
Query: 235 GFYGVNCDKAN 245
G+ G +C + +
Sbjct: 614 GYSGEDCSEVS 624
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 126 bits (316), Expect = 4e-29
Identities = 61/164 (37%), Positives = 74/164 (45%), Gaps = 5/164 (3%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C Q CP GC G C R C C G+ G C C C G C G C+C PG+
Sbjct: 244 CSQRSCPRGCSQRGRCEGGR-CVCDPGYTGDDCGMRSCPRGCSQRGRCEN-GRCVCNPGY 301
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
G +C +C C G C G+C+C PG GE C CP C GG+C+ +C C
Sbjct: 302 TGEDCGVRSCPRGCSQRGRC-KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCV-DGRCVC 359
Query: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
GY G+ CS C C G C E +C C G+ G C R
Sbjct: 360 WPGYTGEDCSTRTCPRDCRGRGRC-EDGECICDTGYSGDDCGVR 402
Score = 125 bits (314), Expect = 6e-29
Identities = 59/165 (35%), Positives = 79/165 (47%), Gaps = 5/165 (3%)
Query: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPG 235
+C CPG C+ G C + +C C GF GP C + C C G C G C+C PG
Sbjct: 212 SCGWPSCPGDCQGRGRC-VQGVCVCRAGFSGPDCSQRSCPRGCSQRGRC-EGGRCVCDPG 269
Query: 236 FYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCK 295
+ G +C +C C G C G+C+C PG GE C + CP+ C G+C +C
Sbjct: 270 YTGDDCGMRSCPRGCSQRGRC-ENGRCVCNPGYTGEDCGVRSCPRGCSQRGRC-KDGRCV 327
Query: 296 CSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
C GY G+ C C CG G C + +C C G+ G C+ R
Sbjct: 328 CDPGYTGEDCGTRSCPWDCGEGGRCVD-GRCVCWPGYTGEDCSTR 371
Score = 121 bits (304), Expect = 9e-28
Identities = 60/164 (36%), Positives = 75/164 (45%), Gaps = 5/164 (3%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C CP CR G C E +C C G+ G C C C G C + G C+C PG+
Sbjct: 430 CGSRACPRDCRGRGRC-ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCES-GRCMCWPGY 487
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
G +C C C G C G+C+C PG GE C +CP CR G C C C
Sbjct: 488 TGRDCGTRACPGDCRGRGRCV-DGRCVCNPGFTGEDCGSRRCPGDCRGHGLC-EDGVCVC 545
Query: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
GY G+ CS C GC G C + +C C++G+ G C R
Sbjct: 546 DAGYSGEDCSTRSCPGGCRGRGQCLD-GRCVCEDGYSGEDCGVR 588
Score = 121 bits (303), Expect = 1e-27
Identities = 60/166 (36%), Positives = 75/166 (45%), Gaps = 10/166 (6%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C CPGGCR G C + R C C DG+ G C C C G+C G CIC G+
Sbjct: 554 CSTRSCPGGCRGRGQCLDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVC-QDGVCICWEGY 611
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
+C C + C G C G+C+C PG G C CP CR G+C+ + C C
Sbjct: 612 VSEDCSIRTCPSNCHGRGRC-EEGRCLCDPGYTGPTCATRMCPADCRGRGRCV-QGVCLC 669
Query: 297 SKGYQGDLCSK-----PVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337
GY G+ C + C GCG C +C C EG+ G C
Sbjct: 670 HVGYGGEDCGQEEPPASACPGGCGPRELC-RAGQCVCVEGFRGPDC 714
Score = 118 bits (296), Expect = 8e-27
Identities = 59/166 (35%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Query: 175 KTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPP 234
+ C CPG CR G C + R C C GF G C C C GLC G C+C
Sbjct: 490 RDCGTRACPGDCRGRGRCVDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC-EDGVCVCDA 547
Query: 235 GFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKC 294
G+ G +C +C C G C G+C+C G GE C + +CP C G C C
Sbjct: 548 GYSGEDCSTRSCPGGCRGRGQCL-DGRCVCEDGYSGEDCGVRQCPNDCSQHGVC-QDGVC 605
Query: 295 KCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
C +GY + CS C C G C E +C C G+ G C R
Sbjct: 606 ICWEGYVSEDCSIRTCPSNCHGRGRCEE-GRCLCDPGYTGPTCATR 650
Score = 116 bits (291), Expect = 3e-26
Identities = 59/164 (35%), Positives = 72/164 (43%), Gaps = 5/164 (3%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C CP C GG C + R C C G+ G C C C G C G CIC G+
Sbjct: 337 CGTRSCPWDCGEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRC-EDGECICDTGY 394
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKC 296
G +C +C C G C G+C+C PG G C CP+ CR G+C C C
Sbjct: 395 SGDDCGVRSCPGDCNQRGRC-EDGRCVCWPGYTGTDCGSRACPRDCRGRGRC-ENGVCVC 452
Query: 297 SKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
+ GY G+ C C C G C E +C C G+ GR C R
Sbjct: 453 NAGYSGEDCGVRSCPGDCRGRGRC-ESGRCMCWPGYTGRDCGTR 495
Score = 93.2 bits (230), Expect = 3e-19
Identities = 48/137 (35%), Positives = 60/137 (43%), Gaps = 7/137 (5%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C CP C G C E R C C G+ GP C +C C G CV G C+C G+
Sbjct: 616 CSIRTCPSNCHGRGRCEEGR-CLCDPGYTGPTCATRMCPADCRGRGRCVQ-GVCLCHVGY 673
Query: 237 YGVNCDKANCSTTCFNGGT----CFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKS 292
G +C + + GG G+C+C G G C I CP CR G+C S
Sbjct: 674 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGS 733
Query: 293 KCKCSKGYQGDLCSKPV 309
C C GY G+ C + V
Sbjct: 734 -CVCKDGYAGEDCGEEV 749
Score = 81.3 bits (199), Expect = 1e-15
Identities = 48/175 (27%), Positives = 68/175 (38%), Gaps = 31/175 (17%)
Query: 181 ECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN 240
+C GGC CP + + T ++G ++ C C PG+ G
Sbjct: 120 QCTGGC-------------CPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPT 166
Query: 241 CD---------------KANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNG 285
C +C C + G C G+C+C PG G C CP C+
Sbjct: 167 CSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVR-GRCVCFPGYTGPSCGWPSCPGDCQGR 225
Query: 286 GKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
G+C+ + C C G+ G CS+ C GC G C E +C C G+ G C R
Sbjct: 226 GRCV-QGVCVCRAGFSGPDCSQRSCPRGCSQRGRC-EGGRCVCDPGYTGDDCGMR 278
Score = 63.2 bits (152), Expect = 4e-10
Identities = 35/103 (33%), Positives = 44/103 (42%), Gaps = 8/103 (7%)
Query: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEK-----ALCTPRCMNGGLCVTPGFC 230
TC CP CR G C + +C C G+ G C + + C C LC G C
Sbjct: 646 TCATRMCPADCRGRGRC-VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELC-RAGQC 703
Query: 231 ICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQC 273
+C GF G +C C C G C + G C+C G GE C
Sbjct: 704 VCVEGFRGPDCAIQTCPGDCRGRGEC-HDGSCVCKDGYAGEDC 745
>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
Length = 2699
Score = 122 bits (305), Expect = 7e-28
Identities = 57/144 (39%), Positives = 75/144 (52%), Gaps = 7/144 (4%)
Query: 198 CECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFYGVNCD--KANCSTTCFNGG 254
C C G+ G CE+A C P C N G+C+ G C C PG+ G NC+ K C C G
Sbjct: 598 CACNSGYKGESCEEADCIDPGCSNHGVCIH-GECHCSPGWGGSNCEILKTMCPDQCSGHG 656
Query: 255 TCFYP-GKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPG 313
T G C C P G C C C + G C+G + C+C +G+ G C++ C P
Sbjct: 657 TYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGT-CRCEEGWTGPACNQRACHPR 715
Query: 314 CGAHGTCHEPNKCQCQEGWHGRHC 337
C HGTC + KC+C +GW+G HC
Sbjct: 716 CAEHGTCKD-GKCECSQGWNGEHC 738
Score = 119 bits (298), Expect = 4e-27
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 44/220 (20%)
Query: 159 SEGNTILQTPQNAIFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALC---- 214
++G Q N I ++ ECP C G C C C GF GP C +A C
Sbjct: 497 NDGKNAEQVSFNTIVIESV--VECPRNCHGNGECVSGT-CHCFPGFLGPDCSRAACPVLC 553
Query: 215 ------------------------------TPRCMNGGLCVTPGFCICPPGFYGVNCDKA 244
P+C G+C+ G C C G+ G +C++A
Sbjct: 554 SGNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRGICIM-GSCACNSGYKGESCEEA 612
Query: 245 NC-STTCFNGGTCFYPGKCICPPGLEGEQCEISK--CPQPCRNGGKCIGKS-KCKCSKGY 300
+C C N G C + G+C C PG G CEI K CP C G + +S C C +
Sbjct: 613 DCIDPGCSNHGVCIH-GECHCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNW 671
Query: 301 QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
G CS +C CG+HG C C+C+EGW G CN+R
Sbjct: 672 TGPDCSNEICSVDCGSHGVC-MGGTCRCEEGWTGPACNQR 710
Score = 106 bits (264), Expect = 4e-23
Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 10/175 (5%)
Query: 175 KTCQQAEC-PGGCRNGGFCNERRICECPDGFHGPHCE--KALCTPRCMNGGLCVTP-GFC 230
++C++A+C GC N G C C C G+ G +CE K +C +C G + G C
Sbjct: 607 ESCEEADCIDPGCSNHGVCIHGE-CHCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSC 665
Query: 231 ICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIG 290
C P + G +C CS C + G C G C C G G C C C G C
Sbjct: 666 TCDPNWTGPDCSNEICSVDCGSHGVCM-GGTCRCEEGWTGPACNQRACHPRCAEHGTC-K 723
Query: 291 KSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNK---CQCQEGWHGRHCNKRYE 342
KC+CS+G+ G+ C+ C C ++G C C CQ GW G C+ E
Sbjct: 724 DGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVAME 778
Score = 88.6 bits (218), Expect = 8e-18
Identities = 49/156 (31%), Positives = 69/156 (44%), Gaps = 13/156 (8%)
Query: 182 CPGGCR-NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN 240
CP C +G + E C C + GP C +C+ C + G+C+ G C C G+ G
Sbjct: 648 CPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMG-GTCRCEEGWTGPA 706
Query: 241 CDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSK---CKCS 297
C++ C C GTC GKC C G GE C I CP C + G+C C C
Sbjct: 707 CNQRACHPRCAEHGTC-KDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLDQNGWHCVCQ 765
Query: 298 KGYQG---DLCSKPVCEPGCGAHG----TCHEPNKC 326
G++G D+ + +C G C +P+ C
Sbjct: 766 PGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDCC 801
>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
Length = 2769
Score = 120 bits (301), Expect = 2e-27
Identities = 62/157 (39%), Positives = 76/157 (48%), Gaps = 10/157 (6%)
Query: 186 CRNGGFCNERRICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFYGVNCD-- 242
C N G C C C G+ G CE+ C P C G+CV G C C G+ G NC+
Sbjct: 635 CSNHGTCITGT-CICNPGYKGESCEEVDCMDPTCSGRGVCVR-GECHCSVGWGGTNCETP 692
Query: 243 KANCSTTCFNGGTCFYP--GKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGY 300
+A C C GT F P G C C P G C I C C G C+G + C+C G+
Sbjct: 693 RATCLDQCSGHGT-FLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGT-CRCEDGW 750
Query: 301 QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337
G C + C P C HGTC + KC+C GW+G HC
Sbjct: 751 MGAACDQRACHPRCAEHGTCRD-GKCECSPGWNGEHC 786
Score = 106 bits (264), Expect = 4e-23
Identities = 60/164 (36%), Positives = 71/164 (43%), Gaps = 11/164 (6%)
Query: 182 CPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNC 241
CP C G C C C GF GP C +A C C G + G C+C G+ G C
Sbjct: 566 CPSNCYGNGDCISGT-CHCFLGFLGPDCGRASCPVLCSGNGQYMK-GRCLCHSGWKGAEC 623
Query: 242 DKAN---CSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKCS 297
D C N GTC G CIC PG +GE CE C P C G C+ + +C CS
Sbjct: 624 DVPTNQCIDVACSNHGTCI-TGTCICNPGYKGESCEEVDCMDPTCSGRGVCV-RGECHCS 681
Query: 298 KGYQGDLCSKP--VCEPGCGAHGT-CHEPNKCQCQEGWHGRHCN 338
G+ G C P C C HGT + C C W G C+
Sbjct: 682 VGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCS 725
Score = 89.4 bits (220), Expect = 5e-18
Identities = 56/186 (30%), Positives = 77/186 (41%), Gaps = 19/186 (10%)
Query: 175 KTCQQAECPGG-CRNGGFCNERRICECPDGFHGPHCE--KALCTPRCM-NGGLCVTPGFC 230
++C++ +C C G C R C C G+ G +CE +A C +C +G G C
Sbjct: 655 ESCEEVDCMDPTCSGRGVC-VRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLC 713
Query: 231 ICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIG 290
C P + G +C C+ C G C G C C G G C+ C C G C
Sbjct: 714 SCDPSWTGHDCSIEICAADCGGHGVC-VGGTCRCEDGWMGAACDQRACHPRCAEHGTC-R 771
Query: 291 KSKCKCSKGYQGDLCS---------KPVCEPGCGAHGTCH---EPNKCQCQEGWHGRHCN 338
KC+CS G+ G+ C+ K C C +G C C CQ GW G C+
Sbjct: 772 DGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD 831
Query: 339 KRYEAS 344
E +
Sbjct: 832 TSMETA 837
Score = 85.1 bits (209), Expect = 9e-17
Identities = 54/167 (32%), Positives = 71/167 (42%), Gaps = 24/167 (14%)
Query: 161 GNTILQTPQNAIFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMN 220
G T +TP+ TC +C G +G F + +C C + G C +C C
Sbjct: 685 GGTNCETPR-----ATCLD-QCSG---HGTFLPDTGLCSCDPSWTGHDCSIEICAADCGG 735
Query: 221 GGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISK--- 277
G+CV G C C G+ G CD+ C C GTC GKC C PG GE C I+
Sbjct: 736 HGVCVG-GTCRCEDGWMGAACDQRACHPRCAEHGTC-RDGKCECSPGWNGEHCTIAHYLD 793
Query: 278 ------CPQPCRNGGKC---IGKSKCKCSKGYQGDLCSKPVCEPGCG 315
CP C G+C + C C G++G C + E CG
Sbjct: 794 RVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSM-ETACG 839
Score = 63.2 bits (152), Expect = 4e-10
Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 245 NCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDL 304
NC + C+ G C G C C G G C + CP C G+ + K +C C G++G
Sbjct: 565 NCPSNCYGNGDCI-SGTCHCFLGFLGPDCGRASCPVLCSGNGQYM-KGRCLCHSGWKGAE 622
Query: 305 CSKPV---CEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
C P + C HGTC C C G+ G C +
Sbjct: 623 CDVPTNQCIDVACSNHGTC-ITGTCICNPGYKGESCEE 659
Score = 47.4 bits (111), Expect = 2e-05
Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 2/64 (3%)
Query: 275 ISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHG 334
+ CP C G CI C C G+ G C + C C +G + +C C GW G
Sbjct: 563 VDNCPSNCYGNGDCI-SGTCHCFLGFLGPDCGRASCPVLCSGNGQ-YMKGRCLCHSGWKG 620
Query: 335 RHCN 338
C+
Sbjct: 621 AECD 624
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 112 bits (279), Expect = 7e-25
Identities = 68/151 (45%), Positives = 76/151 (50%), Gaps = 24/151 (15%)
Query: 186 CRNGGFCN---ERRICECPDGFHGPHCEKA---LCTP-RCMNGGLCVTPG---FCICPPG 235
C NGG C+ + CECP GFHG HCEKA LC+ C NGG C G C CP
Sbjct: 550 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 609
Query: 236 FYGVNCD----KANCSTTCFNGGTCF-YPG--KCICPPGLEGEQCEISKCP---QPCRNG 285
F G +C+ + S C NGGTCF Y G KC CPPG G CEI+ P PC NG
Sbjct: 610 FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNG 669
Query: 286 GKCIGKSK---CKCSKGYQGDLCSKPV-CEP 312
G C + C C GY G C V C P
Sbjct: 670 GTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP 700
Score = 101 bits (251), Expect = 1e-21
Identities = 72/219 (32%), Positives = 86/219 (39%), Gaps = 67/219 (30%)
Query: 186 CRNGGFC--NERRICECPDGFHGPHCEKAL------CTPRCMNGGLCVTPG--------- 228
CRNGG C +C+CP GF G CE + +C +GG C+ G
Sbjct: 474 CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHT 533
Query: 229 ------------------------------FCICPPGFYGVNCDKAN---CST-TCFNGG 254
C CP GF+G +C+KA CS+ C NGG
Sbjct: 534 DHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGG 593
Query: 255 TCFYPG---KCICPPGLEGEQCEISK----CPQPCRNGGKC---IGKSKCKCSKGYQGDL 304
TC G C CP G CEI K PC NGG C IGK KC C G+ G
Sbjct: 594 TCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRH 653
Query: 305 CS---KPVCEPGCGAHGTCHEPNK---CQCQEGWHGRHC 337
C P C GTC + + C CQ G+ GR C
Sbjct: 654 CEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRC 692
Score = 93.2 bits (230), Expect = 3e-19
Identities = 70/235 (29%), Positives = 95/235 (40%), Gaps = 72/235 (30%)
Query: 176 TCQQAECPGG---CRNGGFC---NERRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVT 226
TC+ A+ P C++GG C N +C C G+ G CE + C+P C+NGG CV
Sbjct: 345 TCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVD 404
Query: 227 ---PGFCICPPGFYGVNCDKAN-------CSTTCFNGGTCFYPGK---CICPPGLEGEQC 273
C+C F G+ C+ + S C NGGTC + C CP G G C
Sbjct: 405 LVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDC 464
Query: 274 EISKCPQPC--RNGGKCIGKSK--CKCSKGYQGDLCSKPV----------CEPG--CGAH 317
+ P C RNGG+C+G + C+C G+ G LC + C G C H
Sbjct: 465 R-ERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEH 523
Query: 318 G-----TCHEPNK----------------------------CQCQEGWHGRHCNK 339
G CH + C+C G+HG+HC K
Sbjct: 524 GGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEK 578
Score = 92.8 bits (229), Expect = 5e-19
Identities = 66/183 (36%), Positives = 83/183 (45%), Gaps = 34/183 (18%)
Query: 186 CRNGGFC----NERRICECPDGFHGPHCEKALC---TPRCMNGGLCVT---PGFCICPPG 235
C+NGG C N R C+CP GF GP CE A T C +GG C C+C G
Sbjct: 320 CQNGGTCTHGINSFR-CQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAG 378
Query: 236 FYGVNC--DKANCS-TTCFNGGTCF-YPGK--CICPPGLEGEQCEISKCP-------QPC 282
+ G C D +CS C NGG+C G C+C +G +CE P PC
Sbjct: 379 YTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPC 438
Query: 283 RNGGKCIGKSK---CKCSKGYQGDLCSKPV---CEPGCGAHGTCHEPNK--CQCQEGWHG 334
NGG C+ + C+C +G+ G C + V CE C G C N CQC G+ G
Sbjct: 439 HNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE--CRNGGRCLGANTTLCQCPLGFFG 496
Query: 335 RHC 337
C
Sbjct: 497 LLC 499
Score = 86.7 bits (213), Expect = 3e-17
Identities = 55/148 (37%), Positives = 68/148 (45%), Gaps = 21/148 (14%)
Query: 186 CRNGGFCNER---RICECPDGFHGPHCEKALCTPR---CMNGGLCVT-PG--FCICPPGF 236
C +GG C +R +C C G+ G HCE R C NGG C PG C CP GF
Sbjct: 762 CLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF 821
Query: 237 YGVNCDK---ANCSTTCFNGGTCFYPGK---CICPPGLEGEQCEISKCP---QPCRNGGK 287
GV+C+ A S+ C +GG C G C+CP G CE P PC G
Sbjct: 822 VGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGY 881
Query: 288 CI---GKSKCKCSKGYQGDLCSKPVCEP 312
C+ G C C GY G+ C+K + P
Sbjct: 882 CLASNGSHSCTCKVGYTGEDCAKELFPP 909
Score = 79.3 bits (194), Expect = 5e-15
Identities = 69/209 (33%), Positives = 86/209 (41%), Gaps = 51/209 (24%)
Query: 184 GGCRNGGFCNE---RRICECPDGFHGPHCEKA---LCTPRCMNGGLCV---TPGFCICPP 234
G C NGG C + C+CP GF G HCE A C+NGG C T FC C
Sbjct: 626 GPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQA 685
Query: 235 GFYGVNCD-KANC--------STTCFNG----GTCFY----------PGKC-ICPPG--- 267
G+ G C + +C +T FNG Y P + +C P
Sbjct: 686 GYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVW 745
Query: 268 LEGEQC-EISKC-PQPCRNGGKC---IGKSKCKCSKGYQGDLCSKPVCEPGCGAH----- 317
E QC EI +C QPC +GG C + C CS GY+G C E C AH
Sbjct: 746 SEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDE--CRAHPCRNG 803
Query: 318 GTCHE---PNKCQCQEGWHGRHCNKRYEA 343
G+C C+C G+ G HC +A
Sbjct: 804 GSCRNLPGAYVCRCPAGFVGVHCETEVDA 832
Score = 75.5 bits (184), Expect = 7e-14
Identities = 55/185 (29%), Positives = 79/185 (42%), Gaps = 24/185 (12%)
Query: 218 CMNGGLC---VTPGFCICPPGFYGVNCD--KANCST-TCFNGGTCF-YPGK--CICPPGL 268
C++GG C V C+C G+ G +C+ + C C NGG+C PG C CP G
Sbjct: 762 CLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF 821
Query: 269 EGEQCE--ISKCPQ-PCRNGGKCI---GKSKCKCSK---GYQGDLCSKPVCEPGCGAHGT 319
G CE + C PC++GG+C G C C + GY + S P CG G
Sbjct: 822 VGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGY 881
Query: 320 CHEPN---KCQCQEGWHGRHCNKRY---EASLIHALRPAGAQLRQHTPSLKKAEERRDPP 373
C N C C+ G+ G C K A + + +G + + P+ A + D
Sbjct: 882 CLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGY 941
Query: 374 ESNYI 378
Y+
Sbjct: 942 AVTYV 946
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/81 (34%), Positives = 33/81 (40%), Gaps = 13/81 (16%)
Query: 270 GEQCEISKCPQPCRNGGKCIG-------KSKCKCSKGYQGDLCSKPVCE---PGCGAHGT 319
G + +PC NGGKCI C C G+ G C V E C GT
Sbjct: 266 GHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGT 325
Query: 320 C-HEPN--KCQCQEGWHGRHC 337
C H N +CQC G+ G C
Sbjct: 326 CTHGINSFRCQCPAGFGGPTC 346
Score = 39.3 bits (90), Expect = 0.006
Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 22/86 (25%)
Query: 245 NCSTT-CFNGGTCFYPG----KCICPPGLEGEQCEIS--KCPQPCR------------NG 285
NCS C NGGTC PG C C PG +G +CE++ K +PC G
Sbjct: 1310 NCSENPCQNGGTCV-PGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEG 1368
Query: 286 GKCIGKSKCKCSKGYQGDLCSKPVCE 311
G C K + + +Q D+C K CE
Sbjct: 1369 GVCHHVYK-RVYRVHQ-DICFKESCE 1392
Score = 31.2 bits (69), Expect = 1.6
Identities = 16/31 (51%), Positives = 17/31 (54%), Gaps = 5/31 (16%)
Query: 218 CMNGGLCVTPGF----CICPPGFYGVNCDKA 244
C NGG CV PG C C PGF G C+ A
Sbjct: 1316 CQNGGTCV-PGADAHSCDCGPGFKGRRCELA 1345
Score = 30.0 bits (66), Expect = 3.6
Identities = 13/30 (43%), Positives = 16/30 (53%), Gaps = 3/30 (10%)
Query: 186 CRNGGFC---NERRICECPDGFHGPHCEKA 212
C+NGG C + C+C GF G CE A
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELA 1345
Score = 28.9 bits (63), Expect = 8.0
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 14/77 (18%)
Query: 275 ISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHG 334
+S Q +G K IG CS + + C PG AH C C G+ G
Sbjct: 1290 VSLALQLPEHGSKDIGNVPGNCS---ENPCQNGGTCVPGADAHS-------CDCGPGFKG 1339
Query: 335 RHCNKRYEASLIHALRP 351
R C E + I RP
Sbjct: 1340 RRC----ELACIKVSRP 1352
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 111 bits (278), Expect = 9e-25
Identities = 64/185 (34%), Positives = 88/185 (47%), Gaps = 30/185 (16%)
Query: 186 CRNGGFCNERR----ICECPDGFHGPHCEKALC---TPRCMNGGLCVTP--GF-CICPPG 235
C+NG C+ C C G+ G CE L + C NGG C G+ C+CPPG
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPG 353
Query: 236 FYGVNCDKANCS---TTCFNGGTCFYPGK-----CICPPGLEGEQCE--ISKC-PQPCRN 284
+YG++C+ + S + CFNGG+C + C CPP G CE + +C PC N
Sbjct: 354 YYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCAN 413
Query: 285 GGKCIGKS---KCKCSKGYQGDLCSKPVCEPG---CGAHGTCHEPNK---CQCQEGWHGR 335
GG+C+ + C+C G+ G C V + C GTCH+ C C G+ GR
Sbjct: 414 GGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGR 473
Query: 336 HCNKR 340
C R
Sbjct: 474 RCEVR 478
Score = 100 bits (249), Expect = 2e-21
Identities = 62/189 (32%), Positives = 85/189 (44%), Gaps = 24/189 (12%)
Query: 177 CQQAECPGGCRN-GGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPG 235
CQQ C GC G+C++ C C G+ G C + + C + G C TP C C G
Sbjct: 217 CQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRH-GTCSTPWQCTCDEG 275
Query: 236 FYGVNCDK----ANCSTTCFNGGTCFYPGK----CICPPGLEGEQC--EISKC-PQPCRN 284
+ G+ CD+ + C NG TC G+ C C PG G C E+S+C PCRN
Sbjct: 276 WGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRN 335
Query: 285 GGKCIGKS---KCKCSKGYQGDLCSKPV---CEPGCGAHGTCHEPNK-----CQCQEGWH 333
GG C + C C GY G C + C G+C E N+ C+C +
Sbjct: 336 GGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFT 395
Query: 334 GRHCNKRYE 342
G +C K+ +
Sbjct: 396 GSNCEKKVD 404
Score = 87.4 bits (215), Expect = 2e-17
Identities = 56/154 (36%), Positives = 68/154 (44%), Gaps = 27/154 (17%)
Query: 186 CRNGGFCNERR-----ICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPG---FCICPP 234
C NGG C ER CECP F G +CEK + CT C NGG C+ G C C P
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRP 430
Query: 235 GFYGVNCDK--ANCSTT-CFNGGTCFYPGK---CICPPGLEGEQCEI-----SKCPQPCR 283
GF G C+ ++C+ C +GGTC C CP G G +CE+ + PC
Sbjct: 431 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCF 490
Query: 284 NGGKCIGKSK-----CKCSKGYQGDLCSKPVCEP 312
N C C C G+ G C PV P
Sbjct: 491 NRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLP 524
Score = 78.6 bits (192), Expect = 9e-15
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 3/111 (2%)
Query: 231 ICPPGFYGVNCDK-ANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRN-GGKC 288
IC +YG NC + F C G C PG GE C+ C C G C
Sbjct: 174 ICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYC 233
Query: 289 IGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
++C C G+QG LC++ + GC HGTC P +C C EGW G C++
Sbjct: 234 SKPAECLCRPGWQGRLCNECIPHNGC-RHGTCSTPWQCTCDEGWGGLFCDQ 283
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 110 bits (275), Expect = 2e-24
Identities = 68/180 (37%), Positives = 92/180 (51%), Gaps = 28/180 (15%)
Query: 186 CRNGGFCNE---RRICECPDGFHGPHCEKAL--CTPR-CMNGGLC---VTPGFCICPPGF 236
CRNGG C + C C DG+ G +CE + C+ C NGG C V +C C G+
Sbjct: 638 CRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW 697
Query: 237 YGVNC---DKANCSTTCFNGGTCFYPG---KCICPPGLEGEQCEISK----CPQPCRNGG 286
G C D TC NGGTC+ G KC+CP G EG C I++ P PC NGG
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGG 757
Query: 287 KCI--GKS-KCKCSKGYQGDLCSKPV--CEP-GCGAHGTCHEPN---KCQCQEGWHGRHC 337
C+ G+S C C +G++G +C++ C P C GTC + + +C+C G+ G C
Sbjct: 758 TCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDC 817
Score = 107 bits (267), Expect = 2e-23
Identities = 66/182 (36%), Positives = 85/182 (46%), Gaps = 22/182 (12%)
Query: 177 CQQAECPGGCR-NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPG 235
C +A C GC G C C C G+ G +C+K + P C++ G+C P C+C
Sbjct: 229 CNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVH-GICNEPWQCLCETN 287
Query: 236 FYGVNCDK--ANCST--TCFNGGTCFYPG----KCICPPGLEGEQCEISK---CPQPCRN 284
+ G CDK C T C NGGTC G +C CP G G CEI++ PC N
Sbjct: 288 WGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHN 347
Query: 285 GGKCIGKS---KCKCSKGYQGDLCSKPV--CEP-GCGAHGTCHE---PNKCQCQEGWHGR 335
G C S +C+CS G+ G CS + C P C GTC + KC C W G+
Sbjct: 348 RGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGK 407
Query: 336 HC 337
C
Sbjct: 408 TC 409
Score = 95.5 bits (236), Expect = 7e-20
Identities = 54/162 (33%), Positives = 78/162 (48%), Gaps = 16/162 (9%)
Query: 192 CNERRICECPDGFHGPHCEKALCTPRCM-NGGLCVTPGFCICPPGFYGVNCDKANCSTTC 250
C++ C +G+ GP C +A+C C G C PG C C G+ G+ CDK C
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGC 271
Query: 251 FNGGTCFYPGKCICPPGLEGEQC--EISKC--PQPCRNGGKCIG----KSKCKCSKGYQG 302
+ G C P +C+C G+ C +++ C QPC NGG C K +C C +GY G
Sbjct: 272 VH-GICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330
Query: 303 DLC--SKPVC-EPGCGAHGTCHEPN---KCQCQEGWHGRHCN 338
C ++ C C G+C E + +C+C GW G C+
Sbjct: 331 PNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCS 372
Score = 94.0 bits (232), Expect = 2e-19
Identities = 68/217 (31%), Positives = 92/217 (42%), Gaps = 64/217 (29%)
Query: 186 CRNGGFCNERRI---CECPDGFHGPHCEKAL--CTPR-CMNGGLC--VTPGF-CICPPGF 236
C N G C E + CEC G+ GP C + C+P C +GG C + GF C+CPP +
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQW 404
Query: 237 YGVNC--DKANCSTT-CFNGGTC------FY----PG----------------------- 260
G C D C C N +C +Y PG
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASC 464
Query: 261 -------KCICPPGLEGEQCE--ISKC-PQPCRNGGKC---IGKSKCKCSKGYQGDLCSK 307
+CICPPG G+ CE I +C PC NGG C I + +C C G+ G+LC
Sbjct: 465 RDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL 524
Query: 308 PV--CEPG-CGAHGTCHEPNK---CQCQEGWHGRHCN 338
+ CEP C C+ C+C E + G++C+
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCS 561
Score = 91.7 bits (226), Expect = 1e-18
Identities = 60/181 (33%), Positives = 85/181 (46%), Gaps = 27/181 (14%)
Query: 186 CRNGGFCN----ERRICECPDGFHGPHCE---KALCTPRCMNGGLC--VTPGF-CICPPG 235
C NGG C+ ++ C CP+G+ GP+CE A + C N G C + GF C C PG
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPG 365
Query: 236 FYGVNCDKA--NCS-TTCFNGGTC---FYPGKCICPPGLEGEQCEI--SKCP-QPCRNGG 286
+ G C +CS C +GGTC KC+CPP G+ C++ ++C +PC N
Sbjct: 366 WTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAK 425
Query: 287 KC---IGKSKCKCSKGYQGDLCSKPV--CEPGCGAHGTCHE---PNKCQCQEGWHGRHCN 338
C I C C G+ G C + C C +C + +C C G+ G HC
Sbjct: 426 SCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCE 485
Query: 339 K 339
+
Sbjct: 486 R 486
Score = 91.3 bits (225), Expect = 1e-18
Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 55/211 (26%)
Query: 183 PGGCRNGGFCNERR---ICECPDGFHGP-------HCEKALC--------------TP-- 216
P C+NG C R C+CP+ + G HC C TP
Sbjct: 531 PNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEG 590
Query: 217 -RCMNGGLCVTPG----------FCICPPGFYGVNCDKA--NC-STTCFNGGTCF---YP 259
R ++ +C G C C GF G C + +C S C NGGTC
Sbjct: 591 VRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNS 650
Query: 260 GKCICPPGLEGEQCE--ISKCPQ-PCRNGGKC---IGKSKCKCSKGYQGDLC---SKPVC 310
KCIC G EG CE I+ C Q PC NGG C + C C G++G C
Sbjct: 651 YKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCD 710
Query: 311 EPGCGAHGTCHEPN---KCQCQEGWHGRHCN 338
E C GTC++ KC C GW G CN
Sbjct: 711 EATCNNGGTCYDEGDAFKCMCPGGWEGTTCN 741
Score = 73.6 bits (179), Expect = 3e-13
Identities = 39/110 (35%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Query: 232 CPPGFYGVNCDKANCSTTCFNGG-TCFYPGKCICPPGLEGEQCEISKCPQPCR-NGGKCI 289
C +YG C+K F G C G C G G +C + C Q C G C
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCK 246
Query: 290 GKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
C+C G+QG C K + PGC HG C+EP +C C+ W G+ C+K
Sbjct: 247 LPGDCRCQYGWQGLYCDKCIPHPGC-VHGICNEPWQCLCETNWGGQLCDK 295
Score = 71.6 bits (174), Expect = 1e-12
Identities = 55/160 (34%), Positives = 69/160 (43%), Gaps = 19/160 (11%)
Query: 200 CPDGFHGPHCEKALCTPRCMNGG--LCVTPGFCICPPGFYGVNCDKANCSTTCF-NGGTC 256
C D ++G C K C PR G C G C G+ G C++A C C G+C
Sbjct: 187 CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSC 245
Query: 257 FYPGKCICPPGLEGEQCEISKC-PQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCG 315
PG C C G +G C+ KC P P G C +C C + G LC K + CG
Sbjct: 246 KLPGDCRCQYGWQGLYCD--KCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNY--CG 301
Query: 316 AH------GTCHE--PNK--CQCQEGWHGRHCNKRYEASL 345
H GTC P+K C C EG+ G +C A L
Sbjct: 302 THQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACL 341
Score = 70.1 bits (170), Expect = 3e-12
Identities = 52/153 (33%), Positives = 66/153 (43%), Gaps = 26/153 (16%)
Query: 183 PGGCRNGGFC---NERRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPGF---CICP 233
P C NGG C E C C +G+ GP C + C+P C N G CV C C
Sbjct: 750 PNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECA 809
Query: 234 PGFYGVNC--DKANC-STTCFNGGTC---FYPGKCICPPGLEGEQCEISKCPQPCRNGGK 287
PGF G +C + C S+ C G TC +C+CPPG G +C+ +PC G
Sbjct: 810 PGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ-EVSGRPCITMGS 868
Query: 288 CIGK--------SKCKCSKGYQGDLCSKPVCEP 312
I + C+C G CSK C P
Sbjct: 869 VIPDGAKWDDDCNTCQCLNGRIA--CSKVWCGP 899
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 109 bits (273), Expect = 4e-24
Identities = 71/202 (35%), Positives = 93/202 (46%), Gaps = 34/202 (16%)
Query: 175 KTCQQAE--CPGGCRNGGFC---NERRICECPDGFHGPHCEKAL--CTPR---CMNGGLC 224
K+CQQA+ C NGG C IC CP FHGP C + + C + C +GG C
Sbjct: 136 KSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC 195
Query: 225 ---VTPGFCICPPGFYGVNCDK--ANCS-TTCFNGGTCFYPG----KCICPPGLEGEQCE 274
V C+C G NC++ CS + C NGGTC G +C C PG G+ CE
Sbjct: 196 HNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
Query: 275 --ISKCP-QPCRNGGKC---IGKSKCKCSKGYQGDLCSKPVCE-----PGCGAHGTCHEP 323
I CP C+NGG C + C+C + G C++ V E C GTCH
Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT 315
Query: 324 N---KCQCQEGWHGRHCNKRYE 342
+ C C GW G C++ +
Sbjct: 316 HGGYNCVCVNGWTGEDCSENID 337
Score = 102 bits (253), Expect = 7e-22
Identities = 69/189 (36%), Positives = 85/189 (44%), Gaps = 37/189 (19%)
Query: 186 CRNGGFCNE---RRICECPDGFHGPHCEKAL--CT-PRCMNGGLCV---TPGFCICPPGF 236
CRNG C + C CP GF G HCE CT C NGG CV C+CPPGF
Sbjct: 954 CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF 1013
Query: 237 YGVNC--DKANC-STTCFNGGTC---FYPGKCICPPGLEGEQCE--ISKC-PQPCRNGGK 287
G C D C S C +GGTC +C CP G G C+ + C PC+NGGK
Sbjct: 1014 TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGK 1073
Query: 288 C---IGKSKCKCSKGYQGDLCSKP--VCEPG-----------CGAHGTCHE---PNKCQC 328
C + +C+C G+ G C P CE C G C + + C+C
Sbjct: 1074 CWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRC 1133
Query: 329 QEGWHGRHC 337
Q G+ G +C
Sbjct: 1134 QAGYTGSYC 1142
Score = 101 bits (251), Expect = 1e-21
Identities = 66/193 (34%), Positives = 92/193 (47%), Gaps = 37/193 (19%)
Query: 186 CRNGGFCN--ERR-----ICECPDGFHGPHC----EKALCTPRCMNGGLC----VTPGFC 230
C+N G C+ +RR C C GF GP C + A T C NGG C +T C
Sbjct: 68 CKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKC 127
Query: 231 ICPPGFYGVNCDKAN--CSTTCFNGGTCFYPGK----CICPPGLEGEQC--EISKC---P 279
CPPG+ G +C +A+ S C NGG C P + C CPP G C ++++C P
Sbjct: 128 RCPPGWSGKSCQQADPCASNPCANGGQCL-PFEASYICHCPPSFHGPTCRQDVNECGQKP 186
Query: 280 QPCRNGGKC---IGKSKCKCSKGYQGDLCSKPV--CEPG-CGAHGTCHE----PNKCQCQ 329
CR+GG C +G +C C + G C +P C P C GTC ++C C
Sbjct: 187 GLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACL 246
Query: 330 EGWHGRHCNKRYE 342
G+ G++C + +
Sbjct: 247 PGFTGQNCEENID 259
Score = 92.4 bits (228), Expect = 6e-19
Identities = 67/186 (36%), Positives = 77/186 (41%), Gaps = 29/186 (15%)
Query: 181 ECPGG-CRNGGFCNERR---ICECPDGFHGPHC--EKALCTPRCMNGGLC---VTPGFCI 231
EC G C NGG C + C CP+G+H P C E C G C + C
Sbjct: 681 ECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCD 740
Query: 232 CPPGFYGVNCDKAN--C-STTCFNGGTC--FYPG-KCICPPGLEGEQCE--ISKC-PQPC 282
C PG+ G NCD N C S C NGGTC G C C G G C+ I++C PC
Sbjct: 741 CDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPC 800
Query: 283 RNGGKCI---GKSKCKCSKGYQGDLCS---KPVCEPGCGAHGTC-----HEPNKCQCQEG 331
N G CI KC C Y G C P C G C +E C C G
Sbjct: 801 LNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTG 860
Query: 332 WHGRHC 337
W G+ C
Sbjct: 861 WQGQTC 866
Score = 92.0 bits (227), Expect = 8e-19
Identities = 65/193 (33%), Positives = 85/193 (44%), Gaps = 39/193 (20%)
Query: 181 ECPGG-CRNGGFCNE---RRICECPDGFHGPHC-----EKALCTPRCMNGGLCVTP--GF 229
+CPG C+NGG C + C CP + G +C E L C NGG C G+
Sbjct: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGY 319
Query: 230 -CICPPGFYGVNCDKA--NC-STTCFNGGTC------FYPGKCICPPGLEGEQCEISKC- 278
C+C G+ G +C + +C S CF+G TC FY C CP G G C ++
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFY---CECPHGRTGLLCHLNDAC 376
Query: 279 -PQPCRNGGKCI-----GKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPN-------- 324
PC G C GK+ C C GY G CS+ V E GA+ H
Sbjct: 377 ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSF 436
Query: 325 KCQCQEGWHGRHC 337
+CQC +G+ G C
Sbjct: 437 ECQCLQGYTGPRC 449
Score = 92.0 bits (227), Expect = 8e-19
Identities = 61/189 (32%), Positives = 88/189 (46%), Gaps = 30/189 (15%)
Query: 181 ECPGG-CRNGGFCNERR---ICECPDGFHGPHCEKAL---CTPRCMNGGLCV--TPGF-C 230
EC C NGG C + +C C +GF GP+C+ + + C+N G C+ G+ C
Sbjct: 756 ECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKC 815
Query: 231 ICPPGFYGVNCDK--ANCSTT-CFNGGTC-----FYPGKCICPPGLEGEQCE--ISKCP- 279
C + G C+ A C+ + C NGG C + C+CP G +G+ CE I++C
Sbjct: 816 NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVL 875
Query: 280 QPCRNGGKC---IGKSKCKCSKGYQGDLCSKPV--CEPG-CGAHGTCHEPNK---CQCQE 330
PCR+G C G +C C GY G C + C P C G+C + C C
Sbjct: 876 SPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLP 935
Query: 331 GWHGRHCNK 339
G+ G C +
Sbjct: 936 GFRGTFCEE 944
Score = 89.0 bits (219), Expect = 7e-18
Identities = 64/183 (34%), Positives = 81/183 (44%), Gaps = 31/183 (16%)
Query: 186 CRNGGFC-----NERRICECPDGFHGPHC-----EKALCTPRCMNGGLCV-TPGF--CIC 232
C G C N + IC CP G+ GP C E +L C + G C+ T G C C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC 440
Query: 233 PPGFYGVNC--DKANC-STTCFNGGTCFYP---GKCICPPGLEGEQCEISK---CPQPCR 283
G+ G C D C S C N TC +CIC PG EG CE++ PC
Sbjct: 441 LQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCL 500
Query: 284 NGGKCIGK---SKCKCSKGYQGDLCSKPVCE---PGCGAHGTCHE-PN--KCQCQEGWHG 334
+ G+C+ K +C+C G+ G LC V E C C + PN C C EG+ G
Sbjct: 501 HNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTG 560
Query: 335 RHC 337
HC
Sbjct: 561 THC 563
Score = 88.2 bits (217), Expect = 1e-17
Identities = 57/177 (32%), Positives = 78/177 (44%), Gaps = 25/177 (14%)
Query: 184 GGCRNGGFCNERRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPG---FCICPPGFY 237
G C++G C C G+ G HCE + C+ + C +GG C C C G
Sbjct: 578 GSCKDGV---ATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTT 634
Query: 238 GVNCD--KANCSTTCFNGGTCFYP---GKCICPPGLEGEQCEIS--KCP-QPCRNGGKC- 288
G NC+ +C+++ + GTC +C C PG G C I+ +C PC NGG C
Sbjct: 635 GPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCE 694
Query: 289 --IGKSKCKCSKGYQGDLCSKPV--CEPGCGAHGTCHEP---NKCQCQEGWHGRHCN 338
I C+C +GY C V C HG C + KC C GW G +C+
Sbjct: 695 DGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCD 751
Score = 87.4 bits (215), Expect = 2e-17
Identities = 68/195 (34%), Positives = 87/195 (44%), Gaps = 34/195 (17%)
Query: 176 TCQQ--AEC-PGGCRNGGFCNERR-----ICECPDGFHGPHCE----KALCTPRCMNGGL 223
TC+ A C P CRNGG C + C CP G+ G CE + + +P C +G
Sbjct: 825 TCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP-CRHGAS 883
Query: 224 CVTP--GF-CICPPGFYGVNC--DKANCSTT-CFNGGTC---FYPGKCICPPGLEGEQCE 274
C G+ C C G+ G NC D +C C NGG+C C C PG G CE
Sbjct: 884 CQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCE 943
Query: 275 --ISKCPQ-PCRNGGK---CIGKSKCKCSKGYQGDLC--SKPVC-EPGCGAHGTCHE--- 322
I++C PCRNG C+ C C G+ G C + P C E C GTC +
Sbjct: 944 EDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN 1003
Query: 323 PNKCQCQEGWHGRHC 337
C C G+ G +C
Sbjct: 1004 SFTCLCPPGFTGSYC 1018
Score = 87.0 bits (214), Expect = 2e-17
Identities = 63/198 (31%), Positives = 87/198 (43%), Gaps = 41/198 (20%)
Query: 181 EC-PGGCRNGGFCNERR---ICECPDGFHGPHCEKAL---CTPRCMNGGLCVT-PGF--C 230
EC P C+NG C + C+C G+HG +C + + + C NGG C+ P C
Sbjct: 1148 ECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKC 1207
Query: 231 ICPPGFYGVNC-----------DKANCSTTCFNGGTCFYPG---KCICPPGLEGEQCE-- 274
CP G GV+C D + S CFN GTC C CPPG GE+CE
Sbjct: 1208 SCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGD 1267
Query: 275 ISKC-PQPC--RNGGKCIGKSK---CKCSKGYQGDLCSKPV--CE-PGCGAHGTCHEPNK 325
+++C PC R C+ + C+C G+ G C + C+ C GTC +
Sbjct: 1268 VNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASN 1327
Query: 326 ------CQCQEGWHGRHC 337
C+C G+ G C
Sbjct: 1328 TARGFICKCPAGFEGATC 1345
Score = 83.2 bits (204), Expect = 4e-16
Identities = 72/272 (26%), Positives = 103/272 (37%), Gaps = 62/272 (22%)
Query: 140 CLGKQDGVAAFEVDVIVMN--SEGNTILQTPQNAIFFKTCQQA-----------ECPGG- 185
C + G+ D + N +EG+ P N TC EC G
Sbjct: 361 CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA 420
Query: 186 --CRNGGFCNERR---ICECPDGFHGPHCE----KALCTPRCMNGGLC---VTPGFCICP 233
C + G C C+C G+ GP CE + + P C N C + CIC
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNP-CQNDATCLDQIGEFQCICM 479
Query: 234 PGFYGVNCDKAN---CSTTCFNGGTCF---YPGKCICPPGLEGEQCE--ISKCPQ-PCRN 284
PG+ GV+C+ S+ C + G C +C CP G G C+ + +C PC+N
Sbjct: 480 PGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKN 539
Query: 285 GGKCIGKSK---CKCSKGYQGDLCSKPV--CEPGCGAHGTCHEP---------------- 323
G KC+ C C++GY G C + C+P +G+C +
Sbjct: 540 GAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHH 599
Query: 324 -----NKCQCQEGWHGRHCNKRYEASLIHALR 350
N+C Q HG C R A L L+
Sbjct: 600 CETNINECSSQPCRHGGTCQDRDNAYLCFCLK 631
Score = 79.0 bits (193), Expect = 7e-15
Identities = 59/195 (30%), Positives = 73/195 (37%), Gaps = 45/195 (23%)
Query: 186 CRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLC------------------VTP 227
C NGG C E +G C A PRC + C V
Sbjct: 31 CLNGGKC------EAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVAD 84
Query: 228 GFCICPPGFYGVNC----DKANCSTTCFNGGTC----FYPGKCICPPGLEGEQCEISK-- 277
C C GF G C D A + C NGGTC KC CPPG G+ C+ +
Sbjct: 85 YACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPC 144
Query: 278 CPQPCRNGGKCI---GKSKCKCSKGYQGDLCSKPVCEPG-----CGAHGTCHE---PNKC 326
PC NGG+C+ C C + G C + V E G C GTCH +C
Sbjct: 145 ASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRC 204
Query: 327 QCQEGWHGRHCNKRY 341
C+ G +C + Y
Sbjct: 205 VCRATHTGPNCERPY 219
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/180 (29%), Positives = 72/180 (40%), Gaps = 36/180 (20%)
Query: 186 CRNGGFC----NERR--ICECPDGFHGPHCE---KALCTPRCMNGGLCVT---PGFCICP 233
C+NGG C N R IC+CP GF G CE + + RC+NGG C++ C+C
Sbjct: 1316 CKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCL 1375
Query: 234 PGFYGVNCD---KANC--STTCFNGGTC-------FYPGKCICPPGLEGEQCEISKCPQP 281
F G C + C C+N GTC FY +C+CP G C I
Sbjct: 1376 GPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFY--RCLCPAKFNGLLCHILD---- 1429
Query: 282 CRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRY 341
+ G G+ + C P C+ G + N C GW G C+ +
Sbjct: 1430 -YSFGGGAGRD---IPPPLIEEACELPECQEDAGNKVCSLQCNNHAC--GWDGGDCSLNF 1483
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/113 (28%), Positives = 43/113 (38%), Gaps = 26/113 (23%)
Query: 253 GGTCFYPGK---------CICPPGLEGEQCEISK--CPQPCRNGGKC-------IGKSKC 294
G TC GK C+C G +C+ PC+N G C + C
Sbjct: 28 GETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYAC 87
Query: 295 KCSKGYQGDLCSKPV----CEPGCGAHGTCH----EPNKCQCQEGWHGRHCNK 339
C+ G+ G LC P+ C GTC KC+C GW G+ C +
Sbjct: 88 SCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ 140
Score = 40.0 bits (92), Expect = 0.003
Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 15/76 (19%)
Query: 277 KCPQP---CRNGGKC---IGKSKCKCSKGYQGDLCS--KPVCEPGCGAHGTCHEPNK--- 325
+C QP C NGGKC G C C + G C P C GTCH ++
Sbjct: 23 RCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGV 82
Query: 326 ----CQCQEGWHGRHC 337
C C G+ G C
Sbjct: 83 ADYACSCALGFSGPLC 98
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 109 bits (273), Expect = 4e-24
Identities = 52/151 (34%), Positives = 73/151 (48%), Gaps = 4/151 (2%)
Query: 188 NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCS 247
+G F E C C +G+ G +C + C C + G+CV G CIC + G +C + C
Sbjct: 178 HGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCV-DGQCICDSEYSGDDCSELRCP 236
Query: 248 TTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSK 307
T C + G C G+C+C GE C +CP C G+C C C +GY G+ C +
Sbjct: 237 TDCSSRGLC-VDGECVCEEPYTGEDCRELRCPGDCSGKGRC-ANGTCLCEEGYVGEDCGQ 294
Query: 308 PVCEPGCGAHGTCHEPNKCQCQEGWHGRHCN 338
C C G C E C C+EG+ G C+
Sbjct: 295 RQCLNACSGRGQCEE-GLCVCEEGYQGPDCS 324
Score = 93.6 bits (231), Expect = 3e-19
Identities = 47/134 (35%), Positives = 63/134 (47%), Gaps = 4/134 (2%)
Query: 173 FFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCIC 232
F K C + CP GC + G C + + C C + G C + C C + GLCV G C+C
Sbjct: 195 FGKNCSEPYCPLGCSSRGVCVDGQ-CICDSEYSGDDCSELRCPTDCSSRGLCV-DGECVC 252
Query: 233 PPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKS 292
+ G +C + C C G C G C+C G GE C +C C G+C +
Sbjct: 253 EEPYTGEDCRELRCPGDCSGKGRC-ANGTCLCEEGYVGEDCGQRQCLNACSGRGQC-EEG 310
Query: 293 KCKCSKGYQGDLCS 306
C C +GYQG CS
Sbjct: 311 LCVCEEGYQGPDCS 324
Score = 87.0 bits (214), Expect = 2e-17
Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Query: 194 ERRICECPDGFHGPHCEKALCT------PRCM-NGGLCVTPGFCICPPGFYGVNCDKANC 246
ER + D + C+++ T P C +G CIC G++G NC + C
Sbjct: 145 EREVSVLRDQCNANCCQESAATGQLDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYC 204
Query: 247 STTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCS 306
C + G C G+CIC G+ C +CP C + G C+ +C C + Y G+ C
Sbjct: 205 PLGCSSRGVCV-DGQCICDSEYSGDDCSELRCPTDCSSRGLCV-DGECVCEEPYTGEDCR 262
Query: 307 KPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
+ C C G C C C+EG+ G C +R
Sbjct: 263 ELRCPGDCSGKGRCAN-GTCLCEEGYVGEDCGQR 295
Score = 71.6 bits (174), Expect = 1e-12
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C + CP C + G C + C C + + G C + C C G C G C+C G+
Sbjct: 230 CSELRCPTDCSSRGLCVDGE-CVCEEPYTGEDCRELRCPGDCSGKGRCAN-GTCLCEEGY 287
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGG 286
G +C + C C G C G C+C G +G C P+ R G
Sbjct: 288 VGEDCGQRQCLNACSGRGQC-EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
Score = 33.1 bits (74), Expect = 0.42
Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 1/31 (3%)
Query: 312 PGCGAHGT-CHEPNKCQCQEGWHGRHCNKRY 341
P C HG E C C EGW G++C++ Y
Sbjct: 173 PHCSGHGNFSFESCGCICNEGWFGKNCSEPY 203
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 108 bits (271), Expect = 6e-24
Identities = 70/199 (35%), Positives = 87/199 (43%), Gaps = 47/199 (23%)
Query: 179 QAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCV-TPGFCICPPGFY 237
+ CP G G FC + CP G HGP CE+ C NGG+C G C CP G+
Sbjct: 209 ECRCPPGY-TGAFCEDL----CPPGKHGPQCEQRC---PCQNGGVCHHVTGECSCPSGWM 260
Query: 238 GVNCDKA--------NCSTTC--FNGGTC-FYPGKCICPPGLEGEQCEISKCPQ------ 280
G C + NCS C NGGTC G+C C PG GE+C+ +CP
Sbjct: 261 GTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQ-DECPVGTYGVL 319
Query: 281 -----PCRNGGKCIGKS-KCKCSKGYQGDLCSKPVCEPG-----CGAHGTCHEPN----- 324
C NGGKC S C C G+ G+ C +C G C CH N
Sbjct: 320 CAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCH 379
Query: 325 ----KCQCQEGWHGRHCNK 339
+C C+ GW G +CN+
Sbjct: 380 PMSGECACKPGWSGLYCNE 398
Score = 91.7 bits (226), Expect = 1e-18
Identities = 69/217 (31%), Positives = 87/217 (40%), Gaps = 53/217 (24%)
Query: 173 FFKTCQQAECPGGCRNGGFCNERR-ICECPDGFHGPHCEK--------ALC--TPRCMNG 221
F K C Q EC C NGG C+ C C G+ G C+ LC T +C+NG
Sbjct: 273 FGKNCSQ-ECQ--CHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNG 329
Query: 222 GLCV-TPGFCIC--------------PPGFYGVNCDKANCSTTCFNGGTCF-YPGKCICP 265
G C G C+C P G YG+ CDK C N +C G+C C
Sbjct: 330 GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDK-RCPCHLENTHSCHPMSGECACK 388
Query: 266 PGLEGEQCEISKCPQ----------PCRNGGKCIGKS-KCKCSKGYQGDLCSKPV----- 309
PG G C + P C+NG C + KC C+ G++G CS P
Sbjct: 389 PGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTY 448
Query: 310 ---CEPGCGAHG--TCHEPN-KCQCQEGWHGRHCNKR 340
C CG C + C C+ GWHG C+ R
Sbjct: 449 GINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIR 485
Score = 83.6 bits (205), Expect = 3e-16
Identities = 64/209 (30%), Positives = 87/209 (41%), Gaps = 55/209 (26%)
Query: 183 PGGCRNGGFCN-ERRICECPDGFHGPHCEKALCTP-----RCM--------NGGLCV-TP 227
P C+NG C+ + ICEC GF G C++ +C+P RC + G C
Sbjct: 584 PCYCKNGASCSPDDGICECAPGFRGTTCQR-ICSPGFYGHRCSQTCPQCVHSSGPCHHIT 642
Query: 228 GFCICPPGFYGVNCDKA--------NCS--TTCFNGGTCF-YPGKCICPPGLEGEQCEIS 276
G C C PGF G C++ NC+ TC N GTC C C PG G C
Sbjct: 643 GLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCS-Q 701
Query: 277 KCPQP-----------CRNGGKCIG-KSKCKCSKGYQGDLCSKP------------VCEP 312
CP C NG C +CKC+ G+ G C++ +C+
Sbjct: 702 PCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQ- 760
Query: 313 GCGAHGTC-HEPNKCQCQEGWHGRHCNKR 340
C C H +C C+ G+ GRHC ++
Sbjct: 761 -CQNGADCDHISGQCTCRTGFMGRHCEQK 788
Score = 83.2 bits (204), Expect = 4e-16
Identities = 58/191 (30%), Positives = 77/191 (40%), Gaps = 43/191 (22%)
Query: 187 RNGGFCNERRICECPDGFHGPHCEKALCTPRCMNG---GLCVTPGFCICPPGFYGVNCDK 243
R+G RR +C GF+ +C P C + G C+ P C C PG+ G NC
Sbjct: 81 RHGEKTMYRRKSQCCPGFYE---SGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSS 137
Query: 244 A--------NCST--TCFNGGTCF-YPGKCICPPGLEGEQCEISKCPQ-----------P 281
A +C++ C NG C G C C G G +CE +C Q
Sbjct: 138 ACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCE-DRCEQGTYGNDCHQRCQ 196
Query: 282 CRNGGKCIG-KSKCKCSKGYQGDLCSKPVCEPG-----------CGAHGTCHE-PNKCQC 328
C+NG C +C+C GY G C + +C PG C G CH +C C
Sbjct: 197 CQNGATCDHVTGECRCPPGYTGAFC-EDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSC 255
Query: 329 QEGWHGRHCNK 339
GW G C +
Sbjct: 256 PSGWMGTVCGQ 266
Score = 79.0 bits (193), Expect = 7e-15
Identities = 58/191 (30%), Positives = 71/191 (37%), Gaps = 50/191 (26%)
Query: 198 CECPDGFHGPHCEKALCTPR----------CMNGGLC-VTPGFCICPPGFYGVNCDKA-- 244
C C G+ G HC+ R C NG C G C C PGF G C +
Sbjct: 557 CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICS 616
Query: 245 ------NCSTTC----FNGGTCFY-PGKCICPPGLEGEQCEISKCPQ-----------PC 282
CS TC + G C + G C C PG G C CP C
Sbjct: 617 PGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCN-EVCPSGRFGKNCAGICTC 675
Query: 283 RNGGKC--IGKSKCKCSKGYQGDLCSKPV----CEPGCGAHGTCHE-------PNKCQCQ 329
N G C I +S C+C G+ G CS+P P C CH +C+C
Sbjct: 676 TNNGTCNPIDRS-CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCT 734
Query: 330 EGWHGRHCNKR 340
GW G +C +R
Sbjct: 735 PGWTGLYCTQR 745
Score = 77.4 bits (189), Expect = 2e-14
Identities = 58/197 (29%), Positives = 77/197 (39%), Gaps = 49/197 (24%)
Query: 166 QTPQNAIFFKTCQQAECPGGCRNGGFCNE-RRICECPDGFHGPHCEKAL--------CTP 216
+T + + CQQ C C+NG C+ C C GF G C C+
Sbjct: 398 ETCSPGFYGEACQQI-C--SCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSS 454
Query: 217 RC--MNGGLCV-TPGFCICPPGFYGVNCD----------KANCSTTCFNGGTC-FYPGKC 262
RC N +C G C C G++GV+C N + C NGG C G C
Sbjct: 455 RCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTC 514
Query: 263 ICPPGLEGEQCEISKCPQPCRNGGKCIG-KSKCKCSKGYQGDLCSKPVCEPGCGAHGTCH 321
C PG GE+CE+ PC++G + +C CS C P G
Sbjct: 515 TCAPGWRGEKCEL-----PCQDGTYGLNCAERCDCSHA--------DGCHPTTG------ 555
Query: 322 EPNKCQCQEGWHGRHCN 338
C+C GW G HC+
Sbjct: 556 ---HCRCLPGWSGVHCD 569
Score = 77.4 bits (189), Expect = 2e-14
Identities = 60/187 (32%), Positives = 74/187 (39%), Gaps = 45/187 (24%)
Query: 189 GGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLC-VTPGFCICPPGFYGVNCDKA--- 244
G CNE CP G G +C +CT C N G C C C PG+ G +C +
Sbjct: 653 GALCNE----VCPSGRFGKNCA-GICT--CTNNGTCNPIDRSCQCYPGWIGSDCSQPCPP 705
Query: 245 -----NCSTTC--FNGGTCF-YPGKCICPPGLEGEQCEISKCPQ-----------PCRNG 285
NC TC NG C Y G+C C PG G C +CP C+NG
Sbjct: 706 AHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCT-QRCPLGFYGKDCALICQCQNG 764
Query: 286 GKCIGKS-KCKCSKGYQGDLCSKPVCEPGCGAHG-----------TC-HEPNKCQCQEGW 332
C S +C C G+ G C + C G +G TC H C C GW
Sbjct: 765 ADCDHISGQCTCRTGFMGRHCEQK-CPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGW 823
Query: 333 HGRHCNK 339
G C++
Sbjct: 824 KGARCDQ 830
Score = 47.0 bits (110), Expect = 3e-05
Identities = 34/124 (27%), Positives = 48/124 (38%), Gaps = 38/124 (30%)
Query: 232 CPPGFY--GVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCE------------ISK 277
C PGFY G C +C+ C +G C P C C PG G C S+
Sbjct: 94 CCPGFYESGEMC-VPHCADKCVHG-RCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSR 151
Query: 278 CPQPCRNGGKCIG-KSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRH 336
C C+NG C C C+ G++G C +C++G +G
Sbjct: 152 CQ--CKNGALCNPITGACHCAAGFRGWRCED-------------------RCEQGTYGND 190
Query: 337 CNKR 340
C++R
Sbjct: 191 CHQR 194
Score = 43.9 bits (102), Expect = 2e-04
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 16/73 (21%)
Query: 186 CRNGGFCNE-RRICECPDGFHGPHCE------------KALCTPRCMNGGLCV-TPGFCI 231
C+NG C+ C C GF G HCE + +C C+N C G C
Sbjct: 761 CQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD--CLNNSTCDHITGTCY 818
Query: 232 CPPGFYGVNCDKA 244
C PG+ G CD+A
Sbjct: 819 CSPGWKGARCDQA 831
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 108 bits (270), Expect = 8e-24
Identities = 63/165 (38%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 181 ECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN 240
+C C G C C C GF GP C + C C G G C+C G+ G
Sbjct: 531 DCSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGPE 588
Query: 241 CD--KANC-STTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKC 296
CD + C TCF GTC G CIC PG +GE CE C P C N G C+ K +C C
Sbjct: 589 CDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICV-KGECHC 646
Query: 297 SKGYQGDLCSK--PVCEPGCGAHGT-CHEPNKCQCQEGWHGRHCN 338
S G+ G C PVC+ C HGT + C C W G C+
Sbjct: 647 STGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 691
Score = 107 bits (267), Expect = 2e-23
Identities = 60/171 (35%), Positives = 78/171 (45%), Gaps = 11/171 (6%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHC---EKALCTPRCMNGGLCVTPGFCICP 233
C + CP C G E+ C C G+ GP C E+ P C G C+ G CIC
Sbjct: 558 CARDSCPVLCGGNGEY-EKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIM-GVCICV 615
Query: 234 PGFYGVNCDKANC-STTCFNGGTCFYPGKCICPPGLEGEQCE--ISKCPQPCRNGGK-CI 289
PG+ G C++ +C C N G C G+C C G G CE + C + C G +
Sbjct: 616 PGYKGEICEEEDCLDPMCSNHGICV-KGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLL 674
Query: 290 GKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
C C + G CS +C CG+HG C CQC+EGW G C +R
Sbjct: 675 DAGVCSCDPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEER 724
Score = 104 bits (260), Expect = 1e-22
Identities = 53/145 (36%), Positives = 67/145 (46%), Gaps = 7/145 (4%)
Query: 197 ICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFYGVNCDKAN--CSTTCFNG 253
+C C G+ G CE+ C P C N G+CV G C C G+ GVNC+ C C
Sbjct: 611 VCICVPGYKGEICEEEDCLDPMCSNHGICVK-GECHCSTGWGGVNCETPLPVCQEQCSGH 669
Query: 254 GTCFYP-GKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEP 312
GT G C C P G C C C + G C + C+C +G+ G C + C
Sbjct: 670 GTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC-SRGICQCEEGWVGPTCEERSCHS 728
Query: 313 GCGAHGTCHEPNKCQCQEGWHGRHC 337
C HG C + KC+C GW G HC
Sbjct: 729 HCTEHGQCKD-GKCECSPGWEGDHC 752
Score = 94.0 bits (232), Expect = 2e-19
Identities = 57/177 (32%), Positives = 77/177 (43%), Gaps = 18/177 (10%)
Query: 177 CQQAECPGG-CRNGGFCNERRICECPDGFHGPHCEKAL--CTPRCM-NGGLCVTPGFCIC 232
C++ +C C N G C + C C G+ G +CE L C +C +G + G C C
Sbjct: 623 CEEEDCLDPMCSNHGICVKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSC 681
Query: 233 PPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKS 292
P + G +C C+ C + G C G C C G G CE C C G+C
Sbjct: 682 DPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEERSCHSHCTEHGQC-KDG 739
Query: 293 KCKCSKGYQGDLCS--------KPVCEPGCGAHGTCHEPNK---CQCQEGWHGRHCN 338
KC+CS G++GD C+ + C C +G C C CQ GW G CN
Sbjct: 740 KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Score = 69.3 bits (168), Expect = 5e-12
Identities = 45/147 (30%), Positives = 58/147 (39%), Gaps = 20/147 (13%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C C C + G C+ R IC+C +G+ GP CE+ C C G C G C C PG+
Sbjct: 690 CSTELCTMECGSHGVCS-RGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGW 747
Query: 237 YGVNCDKAN--------CSTTCFNGGTCFYPGK---CICPPGLEGEQCEI---SKCPQPC 282
G +C A+ C CF G C C+C G G C + C
Sbjct: 748 EGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNL 807
Query: 283 RNGG----KCIGKSKCKCSKGYQGDLC 305
N G C+ C+ S Y LC
Sbjct: 808 DNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 17/115 (14%)
Query: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKAL--------CTPRCMNGGLCV-- 225
TC++ C C G C + + CEC G+ G HC A C C G C
Sbjct: 720 TCEERSCHSHCTEHGQCKDGK-CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLD 778
Query: 226 -TPGFCICPPGFYGVNCD---KANCSTTCFNGGTCFYPGKCICPPGLEGEQCEIS 276
C+C G+ G C+ + C N G C+ P + C IS
Sbjct: 779 QNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGL--TDCVDPDCCQQSNCYIS 831
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 108 bits (270), Expect = 8e-24
Identities = 63/165 (38%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 181 ECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN 240
+C C G C C C GF GP C + C C G G C+C G+ G
Sbjct: 530 DCSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGPE 587
Query: 241 CD--KANC-STTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKC 296
CD + C TCF GTC G CIC PG +GE CE C P C N G C+ K +C C
Sbjct: 588 CDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICV-KGECHC 645
Query: 297 SKGYQGDLCSK--PVCEPGCGAHGT-CHEPNKCQCQEGWHGRHCN 338
S G+ G C PVC+ C HGT + C C W G C+
Sbjct: 646 STGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 690
Score = 107 bits (267), Expect = 2e-23
Identities = 60/171 (35%), Positives = 78/171 (45%), Gaps = 11/171 (6%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHC---EKALCTPRCMNGGLCVTPGFCICP 233
C + CP C G E+ C C G+ GP C E+ P C G C+ G CIC
Sbjct: 557 CARDSCPVLCGGNGEY-EKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIM-GVCICV 614
Query: 234 PGFYGVNCDKANC-STTCFNGGTCFYPGKCICPPGLEGEQCE--ISKCPQPCRNGGK-CI 289
PG+ G C++ +C C N G C G+C C G G CE + C + C G +
Sbjct: 615 PGYKGEICEEEDCLDPMCSNHGICV-KGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLL 673
Query: 290 GKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
C C + G CS +C CG+HG C CQC+EGW G C +R
Sbjct: 674 DAGVCSCDPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEER 723
Score = 104 bits (260), Expect = 1e-22
Identities = 53/145 (36%), Positives = 67/145 (46%), Gaps = 7/145 (4%)
Query: 197 ICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFYGVNCDKAN--CSTTCFNG 253
+C C G+ G CE+ C P C N G+CV G C C G+ GVNC+ C C
Sbjct: 610 VCICVPGYKGEICEEEDCLDPMCSNHGICVK-GECHCSTGWGGVNCETPLPVCQEQCSGH 668
Query: 254 GTCFYP-GKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEP 312
GT G C C P G C C C + G C + C+C +G+ G C + C
Sbjct: 669 GTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC-SRGICQCEEGWVGPTCEERSCHS 727
Query: 313 GCGAHGTCHEPNKCQCQEGWHGRHC 337
C HG C + KC+C GW G HC
Sbjct: 728 HCTEHGQCKD-GKCECSPGWEGDHC 751
Score = 94.0 bits (232), Expect = 2e-19
Identities = 57/177 (32%), Positives = 77/177 (43%), Gaps = 18/177 (10%)
Query: 177 CQQAECPGG-CRNGGFCNERRICECPDGFHGPHCEKAL--CTPRCM-NGGLCVTPGFCIC 232
C++ +C C N G C + C C G+ G +CE L C +C +G + G C C
Sbjct: 622 CEEEDCLDPMCSNHGICVKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSC 680
Query: 233 PPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKS 292
P + G +C C+ C + G C G C C G G CE C C G+C
Sbjct: 681 DPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEERSCHSHCTEHGQC-KDG 738
Query: 293 KCKCSKGYQGDLCS--------KPVCEPGCGAHGTCHEPNK---CQCQEGWHGRHCN 338
KC+CS G++GD C+ + C C +G C C CQ GW G CN
Sbjct: 739 KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 795
Score = 69.3 bits (168), Expect = 5e-12
Identities = 45/147 (30%), Positives = 58/147 (39%), Gaps = 20/147 (13%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C C C + G C+ R IC+C +G+ GP CE+ C C G C G C C PG+
Sbjct: 689 CSTELCTMECGSHGVCS-RGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGW 746
Query: 237 YGVNCDKAN--------CSTTCFNGGTCFYPGK---CICPPGLEGEQCEI---SKCPQPC 282
G +C A+ C CF G C C+C G G C + C
Sbjct: 747 EGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNL 806
Query: 283 RNGG----KCIGKSKCKCSKGYQGDLC 305
N G C+ C+ S Y LC
Sbjct: 807 DNDGDGLTDCVDPDCCQQSNCYISPLC 833
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 17/115 (14%)
Query: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKAL--------CTPRCMNGGLCV-- 225
TC++ C C G C + + CEC G+ G HC A C C G C
Sbjct: 719 TCEERSCHSHCTEHGQCKDGK-CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLD 777
Query: 226 -TPGFCICPPGFYGVNCD---KANCSTTCFNGGTCFYPGKCICPPGLEGEQCEIS 276
C+C G+ G C+ + C N G C+ P + C IS
Sbjct: 778 QNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGL--TDCVDPDCCQQSNCYIS 830
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 108 bits (270), Expect = 8e-24
Identities = 63/165 (38%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 181 ECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVN 240
+C C G C C C GF GP C + C C G G C+C G+ G
Sbjct: 531 DCSTNCNGNGECISGH-CHCFPGFLGPDCARDSCPVLCGGNGE-YEKGHCVCRHGWKGPE 588
Query: 241 CD--KANC-STTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKC 296
CD + C TCF GTC G CIC PG +GE CE C P C N G C+ K +C C
Sbjct: 589 CDVPEEQCIDPTCFGHGTCIM-GVCICVPGYKGEICEEEDCLDPMCSNHGICV-KGECHC 646
Query: 297 SKGYQGDLCSK--PVCEPGCGAHGT-CHEPNKCQCQEGWHGRHCN 338
S G+ G C PVC+ C HGT + C C W G C+
Sbjct: 647 STGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCS 691
Score = 107 bits (267), Expect = 2e-23
Identities = 60/171 (35%), Positives = 78/171 (45%), Gaps = 11/171 (6%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHC---EKALCTPRCMNGGLCVTPGFCICP 233
C + CP C G E+ C C G+ GP C E+ P C G C+ G CIC
Sbjct: 558 CARDSCPVLCGGNGEY-EKGHCVCRHGWKGPECDVPEEQCIDPTCFGHGTCIM-GVCICV 615
Query: 234 PGFYGVNCDKANC-STTCFNGGTCFYPGKCICPPGLEGEQCE--ISKCPQPCRNGGK-CI 289
PG+ G C++ +C C N G C G+C C G G CE + C + C G +
Sbjct: 616 PGYKGEICEEEDCLDPMCSNHGICV-KGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLL 674
Query: 290 GKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
C C + G CS +C CG+HG C CQC+EGW G C +R
Sbjct: 675 DAGVCSCDPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEER 724
Score = 104 bits (260), Expect = 1e-22
Identities = 53/145 (36%), Positives = 67/145 (46%), Gaps = 7/145 (4%)
Query: 197 ICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFYGVNCDKAN--CSTTCFNG 253
+C C G+ G CE+ C P C N G+CV G C C G+ GVNC+ C C
Sbjct: 611 VCICVPGYKGEICEEEDCLDPMCSNHGICVK-GECHCSTGWGGVNCETPLPVCQEQCSGH 669
Query: 254 GTCFYP-GKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEP 312
GT G C C P G C C C + G C + C+C +G+ G C + C
Sbjct: 670 GTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC-SRGICQCEEGWVGPTCEERSCHS 728
Query: 313 GCGAHGTCHEPNKCQCQEGWHGRHC 337
C HG C + KC+C GW G HC
Sbjct: 729 HCTEHGQCKD-GKCECSPGWEGDHC 752
Score = 94.0 bits (232), Expect = 2e-19
Identities = 57/177 (32%), Positives = 77/177 (43%), Gaps = 18/177 (10%)
Query: 177 CQQAECPGG-CRNGGFCNERRICECPDGFHGPHCEKAL--CTPRCM-NGGLCVTPGFCIC 232
C++ +C C N G C + C C G+ G +CE L C +C +G + G C C
Sbjct: 623 CEEEDCLDPMCSNHGICVKGE-CHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSC 681
Query: 233 PPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKS 292
P + G +C C+ C + G C G C C G G CE C C G+C
Sbjct: 682 DPKWTGSDCSTELCTMECGSHGVCSR-GICQCEEGWVGPTCEERSCHSHCTEHGQC-KDG 739
Query: 293 KCKCSKGYQGDLCS--------KPVCEPGCGAHGTCHEPNK---CQCQEGWHGRHCN 338
KC+CS G++GD C+ + C C +G C C CQ GW G CN
Sbjct: 740 KCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCN 796
Score = 69.3 bits (168), Expect = 5e-12
Identities = 45/147 (30%), Positives = 58/147 (39%), Gaps = 20/147 (13%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236
C C C + G C+ R IC+C +G+ GP CE+ C C G C G C C PG+
Sbjct: 690 CSTELCTMECGSHGVCS-RGICQCEEGWVGPTCEERSCHSHCTEHGQC-KDGKCECSPGW 747
Query: 237 YGVNCDKAN--------CSTTCFNGGTCFYPGK---CICPPGLEGEQCEI---SKCPQPC 282
G +C A+ C CF G C C+C G G C + C
Sbjct: 748 EGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNL 807
Query: 283 RNGG----KCIGKSKCKCSKGYQGDLC 305
N G C+ C+ S Y LC
Sbjct: 808 DNDGDGLTDCVDPDCCQQSNCYISPLC 834
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 17/115 (14%)
Query: 176 TCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKAL--------CTPRCMNGGLCV-- 225
TC++ C C G C + + CEC G+ G HC A C C G C
Sbjct: 720 TCEERSCHSHCTEHGQCKDGK-CECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLD 778
Query: 226 -TPGFCICPPGFYGVNCD---KANCSTTCFNGGTCFYPGKCICPPGLEGEQCEIS 276
C+C G+ G C+ + C N G C+ P + C IS
Sbjct: 779 QNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGL--TDCVDPDCCQQSNCYIS 831
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 107 bits (268), Expect = 1e-23
Identities = 73/193 (37%), Positives = 89/193 (46%), Gaps = 31/193 (16%)
Query: 176 TCQQA--EC-PGGCRNGGFCNERR---ICECPDGFHGPHCEKALCTPR---CMNGGLCVT 226
TC+ EC P C+NGG C + C CP GF+G CE + T C NGG C
Sbjct: 324 TCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSD 383
Query: 227 P---GF-CICPPGFYGVNCDKA--NCSTT-CFNGGTCFYPGK---CICPPGLEGEQCE-- 274
G+ C CP G+ G NC+K CS++ C NG C G C C G G C+
Sbjct: 384 SPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN 443
Query: 275 ISKCPQ-PCRNGGKC---IGKSKCKCSKGYQGDLCSKPV--CEPG-CGAHGTCHEPNK-- 325
+ C PC NGG C + C C GY G CS PV CE C TCHE
Sbjct: 444 VDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRY 503
Query: 326 -CQCQEGWHGRHC 337
C+C G+ G +C
Sbjct: 504 VCECARGYGGPNC 516
Score = 100 bits (250), Expect = 2e-21
Identities = 63/188 (33%), Positives = 88/188 (46%), Gaps = 23/188 (12%)
Query: 177 CQQAECPGGC-RNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPG 235
C + C GC GFC++ C+C G+ G +C++ + P C++ G C P C C G
Sbjct: 221 CTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLH-GTCQQPWQCNCQEG 279
Query: 236 FYGVNC--DKANCS--TTCFNGGTCFYPGK----CICPPGLEGEQCE--ISKC-PQPCRN 284
+ G+ C D C+ C NG TC G+ C C PG G CE I +C P PC+N
Sbjct: 280 WGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKN 339
Query: 285 GGKCI---GKSKCKCSKGYQGDLC--SKPVCEPG-CGAHGTCHEP----NKCQCQEGWHG 334
GG C C C G+ G +C S C G C G C + C+C G+ G
Sbjct: 340 GGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSG 399
Query: 335 RHCNKRYE 342
+C K+ +
Sbjct: 400 FNCEKKID 407
Score = 97.4 bits (241), Expect = 2e-20
Identities = 63/182 (34%), Positives = 76/182 (41%), Gaps = 29/182 (15%)
Query: 186 CRNGGFCNERR----ICECPDGFHGPHCEKAL--CTPR-CMNGGLCV---TPGFCICPPG 235
C+NG C C C G+ G CE + C P C NGG C C CPPG
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPG 357
Query: 236 FYGVNCDKANCSTT---CFNGGTCFYPG----KCICPPGLEGEQCE--ISKCPQ-PCRNG 285
FYG C+ + + CFNGG C C CP G G CE I C PC NG
Sbjct: 358 FYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNG 417
Query: 286 GKCIGKSK---CKCSKGYQGDLCSKPV---CEPGCGAHGTCHE---PNKCQCQEGWHGRH 336
KC+ C+C G+ G C V C GTC + C C G+ GR+
Sbjct: 418 AKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRN 477
Query: 337 CN 338
C+
Sbjct: 478 CS 479
Score = 96.7 bits (239), Expect = 3e-20
Identities = 65/184 (35%), Positives = 82/184 (44%), Gaps = 34/184 (18%)
Query: 185 GCRNGGFCNERRICECPDGFHGPHCEKAL--CTPR--CMNGGLCVTPG----FCICPPGF 236
GC +G C + C C +G+ G C + L CT C NG C G C C PG+
Sbjct: 262 GCLHGT-CQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGY 320
Query: 237 YGVNCDKA--NCSTT-CFNGGTCF---YPGKCICPPGLEGEQCEISK---CPQPCRNGGK 287
G C+ C + C NGG+C C CPPG G+ CE+S PC NGG+
Sbjct: 321 TGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGR 380
Query: 288 CI----GKSKCKCSKGYQG-------DLCSKPVCEPG--CGAHGTCHEPNKCQCQEGWHG 334
C G C+C GY G D CS C G C G + C+CQ G+ G
Sbjct: 381 CSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAY---LCRCQAGFSG 437
Query: 335 RHCN 338
RHC+
Sbjct: 438 RHCD 441
Score = 90.5 bits (223), Expect = 2e-18
Identities = 54/161 (33%), Positives = 73/161 (45%), Gaps = 16/161 (9%)
Query: 192 CNERRICECPDGFHGPHCEKALCTPRC-MNGGLCVTPGFCICPPGFYGVNCDKANCSTTC 250
C ER C G+ GP+C + +C P C G C PG C C G+ G CD+ C
Sbjct: 204 CGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGC 263
Query: 251 FNGGTCFYPGKCICPPGLEGEQC--EISKCP--QPCRNGGKCI----GKSKCKCSKGYQG 302
+ GTC P +C C G G C +++ C +PC+NG C G C C GY G
Sbjct: 264 LH-GTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322
Query: 303 DLCSKPV--CEPG-CGAHGTC---HEPNKCQCQEGWHGRHC 337
C + C+P C G+C C C G++G+ C
Sbjct: 323 ATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKIC 363
Score = 82.0 bits (201), Expect = 8e-16
Identities = 41/111 (36%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 231 ICPPGFYGVNCDK-ANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPC-RNGGKC 288
+C +YG C F TC G+ +C PG +G C C C G C
Sbjct: 178 VCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFC 237
Query: 289 IGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
+CKC G+QG C + + PGC HGTC +P +C CQEGW G CN+
Sbjct: 238 DKPGECKCRVGWQGRYCDECIRYPGC-LHGTCQQPWQCNCQEGWGGLFCNQ 287
Score = 63.2 bits (152), Expect = 4e-10
Identities = 37/104 (35%), Positives = 45/104 (43%), Gaps = 15/104 (14%)
Query: 186 CRNGGFC---NERRICECPDGFHGPHCEKAL---CTPRCMNGGLC---VTPGFCICPPGF 236
C NG C + +C C GF G HC+ + + C NGG C V C CPPG+
Sbjct: 414 CSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGY 473
Query: 237 YGVNCDK--ANCS-TTCFNGGTCFYPGK---CICPPGLEGEQCE 274
G NC + C C NG TC G C C G G C+
Sbjct: 474 TGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ 517
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 107 bits (268), Expect = 1e-23
Identities = 48/126 (38%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 182 CPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNC 241
C G GF R +C + P +A+C C NGG+C P C CP G+ G C
Sbjct: 3442 CYSGYMLEGFL--RSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLC 3499
Query: 242 DKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQ 301
++ C C NGG C P +C CPPG G +C + C PC NGGKC+ ++C C +
Sbjct: 3500 EEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWT 3559
Query: 302 GDLCSK 307
G CS+
Sbjct: 3560 GHNCSR 3565
Score = 101 bits (251), Expect = 1e-21
Identities = 41/95 (43%), Positives = 51/95 (53%)
Query: 179 QAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYG 238
+A C C+NGG C C CP+G+ G CE+ +C C+NGG CV P C CPPG+ G
Sbjct: 3469 RAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTG 3528
Query: 239 VNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQC 273
C A C + C NGG C P +C C G C
Sbjct: 3529 SRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3563
Score = 99.8 bits (247), Expect = 4e-21
Identities = 43/123 (34%), Positives = 56/123 (45%), Gaps = 12/123 (9%)
Query: 218 CMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISK 277
C+ G +P C +A C C NGG C P C CP G G CE
Sbjct: 3456 CLENGTWTSPPIC------------RAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPI 3503
Query: 278 CPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337
C PC NGG+C+ +C C G+ G C VC+ C G C PN+C C W G +C
Sbjct: 3504 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3563
Query: 338 NKR 340
+++
Sbjct: 3564 SRK 3566
Score = 95.1 bits (235), Expect = 9e-20
Identities = 62/185 (33%), Positives = 86/185 (46%), Gaps = 28/185 (15%)
Query: 181 EC-PGGCRNGGFCNE---RRICECPDGFHGPHCEKAL---CTPRCMNGGLCV--TPGF-C 230
EC P C N G C + ICECP G+ G CE+ + + C+N G+CV G+ C
Sbjct: 1234 ECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRC 1293
Query: 231 ICPPGFYGVNCDKA--NC-STTCFNGGTC---FYPGKCICPPGLEGEQC--EISKC-PQP 281
C GF G++C+ C S C N C C CPPG G +C + +C QP
Sbjct: 1294 TCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP 1353
Query: 282 CRNGGKC---IGKSKCKCSKGYQGDLCSKPV--CEPG-CGAHGTCHE---PNKCQCQEGW 332
C+NG C +C C+ G+ G C + C+ C TC + C+CQ G+
Sbjct: 1354 CKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGF 1413
Query: 333 HGRHC 337
G+ C
Sbjct: 1414 SGKRC 1418
Score = 87.4 bits (215), Expect = 2e-17
Identities = 60/179 (33%), Positives = 81/179 (45%), Gaps = 27/179 (15%)
Query: 186 CRNGGFCNERR---ICECPDGFHGPHCEKAL--CTP-RCMNGGLC---VTPGFCICPPGF 236
C N G C + +C CP G+ G CE + C+P C+N G+C V C CP G+
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1261
Query: 237 YGVNCDK--ANCSTT-CFNGGTC---FYPGKCICPPGLEGEQC--EISKC-PQPCRNGGK 287
G C++ CS++ C N G C +C C G G C E+++C PC N
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV 1321
Query: 288 C---IGKSKCKCSKGYQGDLCSKPVCE---PGCGAHGTCHE---PNKCQCQEGWHGRHC 337
C +G CKC G+ G C K V E C TC + +C C G+ G HC
Sbjct: 1322 CEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHC 1380
Score = 68.6 bits (166), Expect = 9e-12
Identities = 50/149 (33%), Positives = 67/149 (44%), Gaps = 21/149 (14%)
Query: 218 CMNGGLCVTPG---FCICPPGFYGVNC--DKANCS-TTCFNGGTC-FYPGK--CICPPGL 268
C N G C G C+CP G+ G+ C D CS C N G C G+ C CP G
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1261
Query: 269 EGEQCE--ISKC-PQPCRNGGKC---IGKSKCKCSKGYQGDLCSKPV--CEPG-CGAHGT 319
G++CE I++C PC N G C + +C C KG+ G C V C+ C +
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV 1321
Query: 320 CHEP---NKCQCQEGWHGRHCNKRYEASL 345
C + C+C G+ G C K + L
Sbjct: 1322 CEDQVGGFLCKCPPGFLGTRCGKNVDECL 1350
Score = 65.1 bits (157), Expect = 1e-10
Identities = 27/69 (39%), Positives = 36/69 (52%)
Query: 175 KTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPP 234
+ C++ C C NGG C C+CP G+ G C A+C C+NGG CV P C C
Sbjct: 3497 RLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLS 3556
Query: 235 GFYGVNCDK 243
+ G NC +
Sbjct: 3557 SWTGHNCSR 3565
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/110 (32%), Positives = 47/110 (42%), Gaps = 16/110 (14%)
Query: 181 ECPGG-CRNGGFCNERR---ICECPDGFHGPHCEKAL---CTPRCMNGGLC---VTPGFC 230
EC C N C ++ +C+CP GF G C K + + C NG C C
Sbjct: 1310 ECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRC 1369
Query: 231 ICPPGFYGVNCDKA--NC-STTCFNGGTC---FYPGKCICPPGLEGEQCE 274
+C GF G +C+ C S C N TC C C PG G++CE
Sbjct: 1370 LCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 30.4 bits (67), Expect = 2.7
Identities = 36/135 (26%), Positives = 45/135 (33%), Gaps = 23/135 (17%)
Query: 207 PHCEKALC--TPRCMNGGLCVTPGFCI-------CPPGFYGVNCDKANCSTTCF---NGG 254
P C C P+ NG L T G C PG+ V C
Sbjct: 2197 PTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESP 2256
Query: 255 TCFYPGKCICPPGLE-----GEQCEI-SKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKP 308
P C PP ++ GE E+ SK C G + +G S C K + + S P
Sbjct: 2257 LMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNP 2316
Query: 309 VCEPGCGAHGTCHEP 323
C P C EP
Sbjct: 2317 KCMP-----AKCPEP 2326
>gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]
Length = 618
Score = 107 bits (267), Expect = 2e-23
Identities = 72/217 (33%), Positives = 94/217 (43%), Gaps = 55/217 (25%)
Query: 179 QAECPGGCRNG-----GFCNERRICECPDGFHGPHCEKALCT-----PR----------- 217
+ E P CR G GFC + C C +G+ GP C + T PR
Sbjct: 213 ECEAPLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLV 272
Query: 218 ----------CMNGGLC-VTPGF--CICPPGFYGVNCDKANCSTT---CFNGGTCFYPGK 261
C NGG C TP C CP GFYG+ C+ + + CFNGG C
Sbjct: 273 PGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGAD 332
Query: 262 ------CICPPGLEGEQCE--ISKCP-QPCRNGGKCIGKS---KCKCSKGYQGDLCSKPV 309
C CPPG +G CE + +C QPCRNGG C+ +C+C G+ G C +
Sbjct: 333 PDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDL 392
Query: 310 CE---PGCGAHGTCHE---PNKCQCQEGWHGRHCNKR 340
+ C GTC E ++C C G+ GR C +R
Sbjct: 393 DDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRER 429
Score = 95.1 bits (235), Expect = 9e-20
Identities = 60/157 (38%), Positives = 73/157 (46%), Gaps = 24/157 (15%)
Query: 184 GGCRNGGFC------NERRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPGF---CI 231
G C NGG C + IC CP GF G +CEK + C+ + C NGGLC+ G C
Sbjct: 319 GPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCR 378
Query: 232 CPPGFYGVNC--DKANCS-TTCFNGGTCFYPG---KCICPPGLEGEQCEISKCP---QPC 282
C GF G C D +C+ C NGGTC G +C C G G C P +PC
Sbjct: 379 CRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPC 438
Query: 283 RNGGKCIGKSK---CKCSKGYQGDLCSKPVCEPGCGA 316
+GG+C C C+ GY G C PV G A
Sbjct: 439 AHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASA 475
Score = 57.4 bits (137), Expect = 2e-08
Identities = 53/193 (27%), Positives = 73/193 (37%), Gaps = 29/193 (15%)
Query: 175 KTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPP 234
+ C+ P C G R D P +A C+P G C PG C C
Sbjct: 189 RLCRPRSAPSRCGPG----LRPCAPLEDECEAPLVCRAGCSPE---HGFCEQPGECRCLE 241
Query: 235 GFYGVNCDKANCSTTCFNG-GTCFYPGKCICP-PGLEGEQCEISKCPQPCRNGGKCIGKS 292
G+ G C +++C + G C+ P PG C+ PC NGG C
Sbjct: 242 GWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPG----PCD----GNPCANGGSCSETP 293
Query: 293 K---CKCSKGYQGDLC--SKPVCEPG-CGAHGTC---HEPNK---CQCQEGWHGRHCNKR 340
+ C C +G+ G C S C G C G C +P+ C C G+ G +C KR
Sbjct: 294 RSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKR 353
Query: 341 YEASLIHALRPAG 353
+ + R G
Sbjct: 354 VDRCSLQPCRNGG 366
>gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens]
Length = 587
Score = 107 bits (267), Expect = 2e-23
Identities = 72/217 (33%), Positives = 94/217 (43%), Gaps = 55/217 (25%)
Query: 179 QAECPGGCRNG-----GFCNERRICECPDGFHGPHCEKALCT-----PR----------- 217
+ E P CR G GFC + C C +G+ GP C + T PR
Sbjct: 213 ECEAPLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLV 272
Query: 218 ----------CMNGGLC-VTPGF--CICPPGFYGVNCDKANCSTT---CFNGGTCFYPGK 261
C NGG C TP C CP GFYG+ C+ + + CFNGG C
Sbjct: 273 PGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGAD 332
Query: 262 ------CICPPGLEGEQCE--ISKCP-QPCRNGGKCIGKS---KCKCSKGYQGDLCSKPV 309
C CPPG +G CE + +C QPCRNGG C+ +C+C G+ G C +
Sbjct: 333 PDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDL 392
Query: 310 CE---PGCGAHGTCHE---PNKCQCQEGWHGRHCNKR 340
+ C GTC E ++C C G+ GR C +R
Sbjct: 393 DDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRER 429
Score = 95.1 bits (235), Expect = 9e-20
Identities = 60/157 (38%), Positives = 73/157 (46%), Gaps = 24/157 (15%)
Query: 184 GGCRNGGFC------NERRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPGF---CI 231
G C NGG C + IC CP GF G +CEK + C+ + C NGGLC+ G C
Sbjct: 319 GPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCR 378
Query: 232 CPPGFYGVNC--DKANCS-TTCFNGGTCFYPG---KCICPPGLEGEQCEISKCP---QPC 282
C GF G C D +C+ C NGGTC G +C C G G C P +PC
Sbjct: 379 CRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPC 438
Query: 283 RNGGKCIGKSK---CKCSKGYQGDLCSKPVCEPGCGA 316
+GG+C C C+ GY G C PV G A
Sbjct: 439 AHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASA 475
Score = 57.4 bits (137), Expect = 2e-08
Identities = 53/193 (27%), Positives = 73/193 (37%), Gaps = 29/193 (15%)
Query: 175 KTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPP 234
+ C+ P C G R D P +A C+P G C PG C C
Sbjct: 189 RLCRPRSAPSRCGPG----LRPCAPLEDECEAPLVCRAGCSPE---HGFCEQPGECRCLE 241
Query: 235 GFYGVNCDKANCSTTCFNG-GTCFYPGKCICP-PGLEGEQCEISKCPQPCRNGGKCIGKS 292
G+ G C +++C + G C+ P PG C+ PC NGG C
Sbjct: 242 GWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPG----PCD----GNPCANGGSCSETP 293
Query: 293 K---CKCSKGYQGDLC--SKPVCEPG-CGAHGTC---HEPNK---CQCQEGWHGRHCNKR 340
+ C C +G+ G C S C G C G C +P+ C C G+ G +C KR
Sbjct: 294 RSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKR 353
Query: 341 YEASLIHALRPAG 353
+ + R G
Sbjct: 354 VDRCSLQPCRNGG 366
>gi|74136023 delta-like 1 homolog [Homo sapiens]
Length = 383
Score = 106 bits (265), Expect = 3e-23
Identities = 60/185 (32%), Positives = 87/185 (47%), Gaps = 26/185 (14%)
Query: 180 AECPGGCR-NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYG 238
AEC C GFC + +C C G+ GP C++ + +P C++ GLC PG CIC G+ G
Sbjct: 24 AECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLH-GLCGEPGQCICTDGWDG 82
Query: 239 VNCD---KANCSTTCFNGGTCFYPG----KCICPPGLEGEQCEISKCP-----QPCRNGG 286
CD +A S C N GTC +C C PG G+ C+ P PC++GG
Sbjct: 83 ELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142
Query: 287 KCI------GKSKCKCSKGYQGDLCS--KPVCEPG-CGAHGTCHEPN---KCQCQEGWHG 334
C+ + C C G+ G+ C C P C G C + +C+C G+
Sbjct: 143 TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFID 202
Query: 335 RHCNK 339
+ C++
Sbjct: 203 KTCSR 207
Score = 62.0 bits (149), Expect = 9e-10
Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 276 SKCPQPCR-NGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHG 334
++C C G C + C+C G+QG LC + V PGC HG C EP +C C +GW G
Sbjct: 24 AECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLCGEPGQCICTDGWDG 82
Query: 335 RHCNKRYEA 343
C++ A
Sbjct: 83 ELCDRDVRA 91
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 106 bits (265), Expect = 3e-23
Identities = 76/217 (35%), Positives = 94/217 (43%), Gaps = 59/217 (27%)
Query: 175 KTCQQAECPGGCRNGGFCNERR------------ICE--CPDGFHGPHCEKALCTPRCMN 220
K CQ P CR+G C+ R CE CP G HG HCE L P C N
Sbjct: 183 KGCQ---LPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCE--LRCP-CQN 236
Query: 221 GGLCV-TPGFCICPPGFYGVNCDKA--------NCSTTC--FNGGTCFY-PGKCICPPGL 268
GG C G C CPPG+ G C + NCS C +GG C + G+C C G
Sbjct: 237 GGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGY 296
Query: 269 EGEQCEISKCPQ-----------PCRNGGKCIGKS-KCKCSKGYQGDLCSKPVCEPG--- 313
G++C+ +CP C NGG+C + C+C GY+G C + +C G
Sbjct: 297 MGDRCQ-EECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHG 355
Query: 314 --------CGAHGT--CHE-PNKCQCQEGWHGRHCNK 339
C A T CH C CQ GW G HCN+
Sbjct: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNE 392
Score = 94.4 bits (233), Expect = 2e-19
Identities = 69/219 (31%), Positives = 82/219 (37%), Gaps = 61/219 (27%)
Query: 179 QAECPGG-----------CRNGGFCNERR-ICECPDGFHGPHCEKALCTPRCMNGGLCVT 226
Q ECP G C NGG C+ CEC G+ GP C++ LC P ++G C
Sbjct: 302 QEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLC-PEGLHGPGCTL 360
Query: 227 P---------------GFCICPPGFYGVNC----------DKANCSTTCFNGGTCF-YPG 260
P G C C PG+ G +C D TC NG C G
Sbjct: 361 PCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
Query: 261 KCICPPGLEGEQCEIS--------KCPQ--PCRNGGKCIG-KSKCKCSKGYQGDLCSKPV 309
C C PG GE C +S C C NGG C C C +G+QG C+ P
Sbjct: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPC 480
Query: 310 --------CEPGCG-AHGTCHEP--NKCQCQEGWHGRHC 337
C C A+G P C C GW G C
Sbjct: 481 PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC 519
Score = 88.6 bits (218), Expect = 8e-18
Identities = 65/206 (31%), Positives = 86/206 (41%), Gaps = 55/206 (26%)
Query: 186 CRNGGFCN-ERRICECPDGFHGPHCEKALCTPRCMNGG------LCV--------TPGFC 230
C NGG C+ E CEC GF GP C++ +C P G LCV G C
Sbjct: 581 CENGGSCSPEDGSCECAPGFRGPLCQR-ICPPGFYGHGCAQPCPLCVHSSRPCHHISGIC 639
Query: 231 ICPPGFYGVNCDKA--------NCST--TCFNGGTCF-YPGKCICPPGLEGEQCEISKCP 279
C PGF G C++ +C+ +C N GTC G C C PG G+ C CP
Sbjct: 640 ECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCS-QACP 698
Query: 280 Q-----------PCRNGGKCIGKS-KCKCSKGYQGDLCSKP------------VCEPGCG 315
C NG C + C C+ G+ G C++ VC+ C
Sbjct: 699 PGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQ--CQ 756
Query: 316 AHGTC-HEPNKCQCQEGWHGRHCNKR 340
+C H KC C+ G+ G+HC +R
Sbjct: 757 NGASCDHISGKCTCRTGFTGQHCEQR 782
Score = 88.2 bits (217), Expect = 1e-17
Identities = 66/217 (30%), Positives = 86/217 (39%), Gaps = 61/217 (28%)
Query: 182 CPGGCRNGGFC----NERRI---------CECPDGFHGPHCEKAL--------CTPR--C 218
CPG +G FC E + C C G+ GP C C+ R C
Sbjct: 89 CPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQC 148
Query: 219 MNGGLC-VTPGFCICPPGFYGVNCDKANCSTT----------CFNGGTCF-YPGKCICPP 266
NG LC G C+C GF G C++ T C +G +C G+C+C P
Sbjct: 149 QNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAP 208
Query: 267 GLEGEQCEISKCPQ-----------PCRNGGKCIG-KSKCKCSKGYQGDLCSKPVCEPG- 313
G G CE CP PC+NGG C +C C G+ G +C++P C PG
Sbjct: 209 GYTGVYCE-ELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQP-CPPGT 266
Query: 314 --------CGAH--GTC-HEPNKCQCQEGWHGRHCNK 339
C H G C H +C C G+ G C +
Sbjct: 267 FGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQE 303
Score = 85.1 bits (209), Expect = 9e-17
Identities = 60/179 (33%), Positives = 80/179 (44%), Gaps = 39/179 (21%)
Query: 195 RRICECPDGFH--GPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKA-------- 244
RR +C G++ G C LCT C++G CV+P C C PG+ G +C
Sbjct: 83 RRRSQCCPGYYESGDFCIP-LCTEECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGP 140
Query: 245 NCST--TCFNGGTCF-YPGKCICPPGLEGEQCEI----------SKCPQPCRNGGKCIGK 291
+CS C NG C G C+C G G +CE + P CR+G C +
Sbjct: 141 HCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPR 200
Query: 292 S-KCKCSKGYQGDLCSKPVCEPGC-GAH----------GTCHE-PNKCQCQEGWHGRHC 337
+ +C C+ GY G C + +C PG GAH GTCH +C C GW G C
Sbjct: 201 AGECLCAPGYTGVYCEE-LCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVC 258
Score = 83.6 bits (205), Expect = 3e-16
Identities = 70/249 (28%), Positives = 91/249 (36%), Gaps = 89/249 (35%)
Query: 176 TCQQ-AEC---PGGCRNG-GFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCV-TPGF 229
TCQ A+C GGC GF E C G +GP+C ++C+ C NGG C G
Sbjct: 408 TCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCS-SICS--CNNGGTCSPVDGS 464
Query: 230 CICPPGFYGVNCD----------KANCSTTCFNGGTCF-YPGKCICPPGLEGEQCEI--- 275
C C G+ G++C N S TC NG C G C C PG G+ CE+
Sbjct: 465 CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCP 524
Query: 276 ---------------------------------------SKCPQ-----------PCRNG 285
S CP C NG
Sbjct: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENG 584
Query: 286 GKCIGK-SKCKCSKGYQGDLCSKPVCEPGCGAHG-------------TCHE-PNKCQCQE 330
G C + C+C+ G++G LC + +C PG HG CH C+C
Sbjct: 585 GSCSPEDGSCECAPGFRGPLCQR-ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLP 643
Query: 331 GWHGRHCNK 339
G+ G CN+
Sbjct: 644 GFSGALCNQ 652
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/134 (29%), Positives = 51/134 (38%), Gaps = 35/134 (26%)
Query: 175 KTCQQAECPGG-----------CRNGGFCN-ERRICECPDGFHGPHCEKALCTP------ 216
K C QA CP G C NG C+ E C C G+ G C +
Sbjct: 691 KDCSQA-CPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDC 749
Query: 217 ----RCMNGGLCV-TPGFCICPPGFYGVNCDKANCSTT----------CFNGGTCFY-PG 260
+C NG C G C C GF G +C++ T C N TC + G
Sbjct: 750 GRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTG 809
Query: 261 KCICPPGLEGEQCE 274
C C PG +G +C+
Sbjct: 810 TCYCSPGFKGIRCD 823
Score = 52.8 bits (125), Expect = 5e-07
Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 17/87 (19%)
Query: 171 AIFFKTCQQAECPGGCRNGGFCNE-RRICECPDGFHGPHCEKALCTP-----------RC 218
A F K C + C C+NG C+ C C GF G HCE+ C P C
Sbjct: 743 AFFGKDCGRV-CQ--CQNGASCDHISGKCTCRTGFTGQHCEQR-CAPGTFGYGCQQLCEC 798
Query: 219 MNGGLCV-TPGFCICPPGFYGVNCDKA 244
MN C G C C PGF G+ CD+A
Sbjct: 799 MNNSTCDHVTGTCYCSPGFKGIRCDQA 825
Score = 45.4 bits (106), Expect = 8e-05
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 283 RNGGKCIGKSKCKCSKGY--QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCN 338
R G + + + + +C GY GD C P+C C HG C P+ C C+ GW G C+
Sbjct: 75 RRGLRTMYRRRSQCCPGYYESGDFCI-PLCTEEC-VHGRCVSPDTCHCEPGWGGPDCS 130
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 105 bits (262), Expect = 7e-23
Identities = 63/184 (34%), Positives = 79/184 (42%), Gaps = 24/184 (13%)
Query: 177 CQQAECPGGCRNGGFCNE----RRICECPDGFHGPHCEKALCTPRCMNGGLC-VTPG--- 228
C+ C C+NGG C R C C GF GP+C K +C C NGG C VT G
Sbjct: 4248 CEVNHCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQP 4307
Query: 229 FCICPPGFYGVNCDKANCSTTCFNGGTCFYPG----KCICPPGLEGEQCEISKCPQPCRN 284
+C C P + G C C C N +C +C+CP EG +CE+ KC + C
Sbjct: 4308 YCHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCVR-CHG 4366
Query: 285 GGKCIGKSK----CKCSKGYQGDLCSKPVCEPGCGAHGTCH---EPN--KCQCQEGWHGR 335
G I K C C+ G C +C+ C GTC E N C C W G
Sbjct: 4367 GHCIINKDSEDIFCNCTNGKIASSCQ--LCDGYCYNGGTCQLDPETNVPVCLCSTNWSGT 4424
Query: 336 HCNK 339
C +
Sbjct: 4425 QCER 4428
Score = 94.7 bits (234), Expect = 1e-19
Identities = 68/235 (28%), Positives = 89/235 (37%), Gaps = 30/235 (12%)
Query: 127 VPHKASVVQVGFPCLGKQDGVAAFEVDVIVMNSEGNTILQTPQNAIFFKTCQQAE----- 181
+ H+ + + PCL D F + ++N G T + + TC
Sbjct: 4163 ISHRYKQLDLPNPCL---DLACEF---LCLLNPSGATCVCPEGKYLINGTCNDDSLLDDS 4216
Query: 182 CPGGCRNGGFC--NERRI--CECPDGFHGPHCEKALCTPRCMNGGLCVTPGF----CICP 233
C C NGG C NE+ C C + G CE C+ C NGG CV C C
Sbjct: 4217 CKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVNHCSNYCQNGGTCVPSVLGRPTCSCA 4276
Query: 234 PGFYGVNCDKANCSTTCFNGGTCFYPG----KCICPPGLEGEQCEISKCPQPCRNGGKCI 289
GF G NC K C C NGGTC C C P G++C+ C C N C
Sbjct: 4277 LGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNSESCT 4336
Query: 290 ----GKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNK---CQCQEGWHGRHC 337
G +C C Y+G C C G H ++ ++ C C G C
Sbjct: 4337 IGDDGSVECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNGKIASSC 4391
Score = 40.4 bits (93), Expect = 0.003
Identities = 50/190 (26%), Positives = 71/190 (37%), Gaps = 50/190 (26%)
Query: 186 CRNGGFC-NERRICE----CPDGFHGPHCEKALCTPR---CMNG-GLCVTP-----GFCI 231
C + G C N+ +C+ C D C+ LC P C N +C+ P G
Sbjct: 1103 CWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQPEKLCNGKKD 1162
Query: 232 CPPGF-YGVNCDKANCSTTCFNGGTCFYPGK---CICPPGLEGEQCEISKCPQPCRNGGK 287
CP G G CD+ + + + PG+ C CP GL+ ++K + C
Sbjct: 1163 CPDGSDEGYLCDECSLNNGGCSNHCSVVPGRGIVCSCPEGLQ-----LNKDNKTCEIVDY 1217
Query: 288 CIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPN-KCQCQEGW----HGRHCNK--R 340
C KC VCE H+ KC C EGW G C
Sbjct: 1218 CSNHLKCS------------QVCEQ--------HKHTVKCSCYEGWKLDVDGESCTSVDP 1257
Query: 341 YEASLIHALR 350
+EA +I ++R
Sbjct: 1258 FEAFIIFSIR 1267
Score = 36.2 bits (82), Expect = 0.050
Identities = 39/140 (27%), Positives = 50/140 (35%), Gaps = 28/140 (20%)
Query: 199 ECPDGFHGPH-CEKALCTP---RCMNGGLCVTPGFCICPPGFYGVNCDKANCST-TCFNG 253
+C DG P C + C P +C GLC P F G N D+ NC T C +G
Sbjct: 3341 DCGDGSDEPDDCPEFRCQPGRFQC-GTGLCALPAFICDGENDCGDNSDELNCDTHVCLSG 3399
Query: 254 G-TCFYPGKCICPPGLE-------GEQCEISKCPQ--------PCRNGGKCIGK-----S 292
C KCI P L G++ + CP+ C+ CI K
Sbjct: 3400 QFKCTKNQKCI-PVNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDE 3458
Query: 293 KCKCSKGYQGDLCSKPVCEP 312
C+ C K C P
Sbjct: 3459 DPDCADASDEANCDKKTCGP 3478
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 100 bits (248), Expect = 3e-21
Identities = 64/194 (32%), Positives = 87/194 (44%), Gaps = 28/194 (14%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPR----CMNGGLCV-TPGF-- 229
C + C G R + R +C CP G+ G C + R C +GG C+ TPG
Sbjct: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFR 182
Query: 230 CICPPGFYGVNCDK--ANCS-TTCFNGGTCFYPG----KCICPPGLEGEQCEIS--KCP- 279
C CP G+ G C+ C+ + C NGGTC G C C PG EG+ CE++ CP
Sbjct: 183 CQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPG 242
Query: 280 QPCRNGGKC---IGKSKCKCSKGYQGDLCSKPVCE-----PGCGAHGTCHEP---NKCQC 328
C NGG C + C+C + G C++ V E C GTC + C C
Sbjct: 243 HRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVC 302
Query: 329 QEGWHGRHCNKRYE 342
GW G C++ +
Sbjct: 303 VNGWTGESCSQNID 316
Score = 99.4 bits (246), Expect = 5e-21
Identities = 81/253 (32%), Positives = 105/253 (41%), Gaps = 50/253 (19%)
Query: 139 PCLGK---QDGVAAFEVDVIVMNSEGNTILQTPQNAIFFKTCQQAEC-PGGCRN--GGFC 192
PCL QDGV +F + P+ A C C PG C + F
Sbjct: 857 PCLNGGSCQDGVGSFSCSCLPG-------FAGPRCARDVDECLSNPCGPGTCTDHVASFT 909
Query: 193 NERRICECPDGFHGPHCEKAL--CTPR-CMNGGLCV---TPGFCICPPGFYGVNCDKAN- 245
C CP G+ G HCE+ L C+P C NGG CV C+C PG+ G +C
Sbjct: 910 -----CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEAD 964
Query: 246 --CSTTCFNGGTCF--YPG-KCICPPGLEGEQCE--ISKCP-QPCRNGGKCIGKSK-CKC 296
S C +GG C +PG +C C G QC+ + C QPC+NGG+C+ C C
Sbjct: 965 PCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLC 1024
Query: 297 SKGYQGDLC---SKPVCEPG----------CGAHGTCHEPNK---CQCQEGWHGRHCNKR 340
G+ G LC S P E C A G C + + C C EG G HC +
Sbjct: 1025 PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQE 1084
Query: 341 YEASLIHALRPAG 353
+ L + G
Sbjct: 1085 VDPCLAQPCQHGG 1097
Score = 98.6 bits (244), Expect = 8e-21
Identities = 68/190 (35%), Positives = 83/190 (43%), Gaps = 35/190 (18%)
Query: 184 GGCRNGGFCNE-------RRICECPDGFHGPHC---EKALCTPRCMNGGLC-VTPG---F 229
G C G C R C CP GF GP C + L +P C +G C V P
Sbjct: 85 GPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSP-CAHGARCSVGPDGRFL 143
Query: 230 CICPPGFYGVNC----DKANCSTTCFNGGTCF-YPG--KCICPPGLEGEQCE---ISKCP 279
C CPPG+ G +C D+ C +GGTC PG +C CP G G CE + P
Sbjct: 144 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAP 203
Query: 280 QPCRNGGKCIGKS----KCKCSKGYQGDLCSKPVCE-PG--CGAHGTCHE---PNKCQCQ 329
PCRNGG C C C G++G C V + PG C GTC + CQC
Sbjct: 204 SPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCP 263
Query: 330 EGWHGRHCNK 339
W G+ C +
Sbjct: 264 PEWTGQFCTE 273
Score = 98.6 bits (244), Expect = 8e-21
Identities = 64/186 (34%), Positives = 83/186 (44%), Gaps = 32/186 (17%)
Query: 183 PGGCRNGGFCNE---RRICECPDGFHGPHCEKAL--CTPRCMNGGLC---VTPGFCICPP 234
P C NGG C + C C GF GP C + + C G C V C CPP
Sbjct: 855 PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPP 914
Query: 235 GFYGVNC--DKANCS-TTCFNGGTCF---YPGKCICPPGLEGEQCEISKCP---QPCRNG 285
G+ G +C D +CS ++CFNGGTC C+C PG G C+ P +PC +G
Sbjct: 915 GYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHG 974
Query: 286 GKCIGKS---KCKCSKGYQG-------DLCSKPVCEPGCGAHGTCHEPNK-CQCQEGWHG 334
G C +C C + + G D CS+ C+ G G C + C C GW G
Sbjct: 975 GVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNG----GRCVQTGAYCLCPPGWSG 1030
Query: 335 RHCNKR 340
R C+ R
Sbjct: 1031 RLCDIR 1036
Score = 96.3 bits (238), Expect = 4e-20
Identities = 63/185 (34%), Positives = 85/185 (45%), Gaps = 33/185 (17%)
Query: 186 CRNGGFCNE----RRICECPDGFHGPHC--EKALCTPRCMNGGLC---VTPG----FCIC 232
C NGG C + C CP G+ G C E + C G+C V G C C
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
Query: 233 PPGFYGVNCDKAN--CSTTCFNGGTCFY--PGK--CICPPGLEGEQC--EISKC--PQPC 282
P GF G +C + S+ C +G C G+ C CPPG +G C ++ +C +PC
Sbjct: 109 PRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPC 168
Query: 283 RNGGKCI---GKSKCKCSKGYQGDLCSKPV--CEPG-CGAHGTCHEPN----KCQCQEGW 332
R+GG C+ G +C+C GY G LC P C P C GTC + C C G+
Sbjct: 169 RHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGF 228
Query: 333 HGRHC 337
G++C
Sbjct: 229 EGQNC 233
Score = 94.0 bits (232), Expect = 2e-19
Identities = 65/189 (34%), Positives = 83/189 (43%), Gaps = 30/189 (15%)
Query: 181 ECPGG-CRNGGFCNERRI---CECPDGFHGPHC--EKALCTPRCMNGGLCVTP--GF-CI 231
EC C GG C + C CP G P C C + G+C GF C+
Sbjct: 660 ECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCV 719
Query: 232 CPPGFYGVNCDKANC-----STTCFNGGTCFYPGK---CICPPGLEGEQCE-ISKC-PQP 281
C PG+ G C ++ S C GGTC G C CPPG++G QCE +S C P P
Sbjct: 720 CEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 779
Query: 282 CRNGGKCIGK----SKCKCSKGYQGDLCSKPVCE----PGCGAHGTCHE---PNKCQCQE 330
C +GG+C C C +G+QG C + V E CG HG C C C
Sbjct: 780 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG 839
Query: 331 GWHGRHCNK 339
G+ G C++
Sbjct: 840 GYTGPSCDQ 848
Score = 92.0 bits (227), Expect = 8e-19
Identities = 66/185 (35%), Positives = 82/185 (44%), Gaps = 28/185 (15%)
Query: 181 ECPGG-CRNGGFCNERR---ICECPDGFHGPHCE----KALCTPRCMNGGLCVTP--GF- 229
EC C NGG C +R C CP GF G C+ + TP C NG CV G+
Sbjct: 472 ECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTP-CRNGAKCVDQPDGYE 530
Query: 230 CICPPGFYGVNCDKA--NCSTTCFNGGTC---FYPGKCICPPGLEGEQCE--ISKC-PQP 281
C C GF G CD+ +CS + G C C C PG G +CE + +C QP
Sbjct: 531 CRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP 590
Query: 282 CRNGGKC---IGKSKCKCSKGYQGDLCSKPV--CEPGCGAHGTCHE---PNKCQCQEGWH 333
CR+GGKC + K C+C G G C + C G C + C CQ G+
Sbjct: 591 CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFT 650
Query: 334 GRHCN 338
G CN
Sbjct: 651 GPLCN 655
Score = 90.9 bits (224), Expect = 2e-18
Identities = 66/199 (33%), Positives = 86/199 (43%), Gaps = 38/199 (19%)
Query: 177 CQQ--AEC-PGGCRNGGFCNE---RRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVT- 226
C+Q +C P C NGG C + C C G+ G HC+ C R C++GG+C
Sbjct: 921 CEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAA 980
Query: 227 -PGF-CICPPGFYGVNCDKAN--CSTT-CFNGGTCFYPGK-CICPPGLEGEQCEISKCP- 279
PGF C C F G C CS C NGG C G C+CPPG G C+I P
Sbjct: 981 HPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPC 1040
Query: 280 ------------QPCRNGGKCIGKSK---CKCSKGYQGDLCSK---PVCEPGCGAHGTCH 321
Q C+ GG+C+ + C C +G G C + P C GTC
Sbjct: 1041 REAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCR 1100
Query: 322 ---EPNKCQCQEGWHGRHC 337
C+C G++G +C
Sbjct: 1101 GYMGGYMCECLPGYNGDNC 1119
Score = 90.5 bits (223), Expect = 2e-18
Identities = 62/187 (33%), Positives = 79/187 (42%), Gaps = 35/187 (18%)
Query: 186 CRNGGFCNERRI---CECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPG-FCICPPGFYG 238
C +GG C+ C C + F GP C+ + C+ + C NGG CV G +C+CPPG+ G
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSG 1030
Query: 239 VNCD-------------KANCSTTCFNGGTCFYPGK---CICPPGLEGEQCEISKCP--- 279
CD C GG C C+CP G G CE P
Sbjct: 1031 RLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLA 1090
Query: 280 QPCRNGGKC---IGKSKCKCSKGYQGDLCSKPVCE---PGCGAHGTCHE---PNKCQCQE 330
QPC++GG C +G C+C GY GD C V E C G+C + C C
Sbjct: 1091 QPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPP 1150
Query: 331 GWHGRHC 337
G G C
Sbjct: 1151 GTLGVLC 1157
Score = 85.1 bits (209), Expect = 9e-17
Identities = 67/236 (28%), Positives = 87/236 (36%), Gaps = 68/236 (28%)
Query: 186 CRNGGFC-----NERRICECPDGFHGPHCEK------------------------ALCT- 215
C C N R IC CP GF G C++ LC
Sbjct: 360 CHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 419
Query: 216 ------PR------------CMNGGLC---VTPGFCICPPGFYGVNC--DKANC-STTCF 251
PR C N C + CIC GF G C D C S+ C
Sbjct: 420 GRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCV 479
Query: 252 NGGTC---FYPGKCICPPGLEGEQC--EISKCPQ-PCRNGGKCIGKS---KCKCSKGYQG 302
NGG C C CP G G C ++ +C PCRNG KC+ + +C+C++G++G
Sbjct: 480 NGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEG 539
Query: 303 DLCSKPV--CEPGCGAHGTCHE---PNKCQCQEGWHGRHCNKRYEASLIHALRPAG 353
LC + V C P HG C + C C G+ G C + + R G
Sbjct: 540 TLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGG 595
Score = 75.5 bits (184), Expect = 7e-14
Identities = 61/195 (31%), Positives = 82/195 (42%), Gaps = 44/195 (22%)
Query: 186 CRNGGFCNE---RRICECPDGFHGPHCE----------KALCTPRCMNGGLCV--TPGF- 229
C++GG C + R +C CP G G CE PRC++ G CV GF
Sbjct: 1131 CQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFR 1190
Query: 230 CICPPGFYGVNC--DKANC-STTCFNGGT--CFY-PG---KCICPPGLEGEQCE--ISKC 278
C CPPG+ G+ C D C S C T C PG +C+C G G +C+ +S C
Sbjct: 1191 CTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPC 1250
Query: 279 -PQPCRNGGKCIGKS--------KCKCSKGYQGDLCSKPV-------CEPGCGAHGTCHE 322
QPC++GG+C C C++ + G C + C G T
Sbjct: 1251 ESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRG 1310
Query: 323 PNKCQCQEGWHGRHC 337
P +C C G G C
Sbjct: 1311 P-RCACPPGLSGPSC 1324
Score = 65.9 bits (159), Expect = 6e-11
Identities = 51/176 (28%), Positives = 65/176 (36%), Gaps = 36/176 (20%)
Query: 198 CECPDGFHGPHCEKALC---TPRCMNGGLC-VTPG-------FCICPPGFYGVNCDKANC 246
C C GF GP C+ L + C +GG C +PG C C F+G C++
Sbjct: 1232 CLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVAR 1291
Query: 247 STT---CFNGGTCFYPGK---CICPPGLEGEQC-----------EISKCPQPCRNGGKCI 289
S C G C + C CPPGL G C S PC +GG C
Sbjct: 1292 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCR 1351
Query: 290 GKS-----KCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWH--GRHCN 338
+C C++G+ G C P P C CQ + G R CN
Sbjct: 1352 PAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRA-ACQAKRGDQRCDRECN 1406
Score = 47.8 bits (112), Expect = 2e-05
Identities = 54/223 (24%), Positives = 74/223 (33%), Gaps = 57/223 (25%)
Query: 175 KTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPR-----------CMNGGL 223
++C++ +CP G R C CP G GP C +P C++GG
Sbjct: 1291 RSCRELQCPVGVPCQQTPRGPR-CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGS 1349
Query: 224 C----VTPGF-CICPPGFYGVNCDKA------------------------NCSTTCFNGG 254
C + P F C C G+ G C+ C C + G
Sbjct: 1350 CRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG 1409
Query: 255 TCFYPGKCICPPGLEGEQCEISKC--------PQPCRNGGKCIGKSKCKCSKGYQGDLCS 306
+ G C G QCE +C P + C+ C G + C+
Sbjct: 1410 CGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACL-YDNFDCHAGGRERTCN 1468
Query: 307 KPVCEPGCGAH---GTCHEPNKCQCQE-GWHGRHCNKRYEASL 345
PV E C H G C + C +E GW G C A L
Sbjct: 1469 -PVYEKYCADHFADGRCDQ--GCNTEECGWDGLDCASEVPALL 1508
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 22/87 (25%)
Query: 265 PPGLEGEQCEISKCPQPCRNGGKCI----GKSKCKCSKGYQGDLCS-KPVCEPG-CGAHG 318
PP L+G PC NGG+C ++ C C G+ G+ C + C G C G
Sbjct: 41 PPCLDGS---------PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRG 91
Query: 319 TCHEP-------NKCQCQEGWHGRHCN 338
C C+C G+ G C+
Sbjct: 92 VCQSSVVAGTARFSCRCPRGFRGPDCS 118
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 99.4 bits (246), Expect = 5e-21
Identities = 64/188 (34%), Positives = 84/188 (44%), Gaps = 32/188 (17%)
Query: 186 CRNGGFC----NERRICECPDGFHGPHCE-KALCTP-RCMNGGLCVTPGF-----CICPP 234
C N G C N C+CP+GF G +C+ + C RC NGG CV C C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 235 GFYGVNCDKAN-----CSTTCFNGGTCFYPGK----CICPPGLEGEQCEISKC--PQPCR 283
GF G +C + S C NGGTC + C C G G++C+ + PC
Sbjct: 95 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154
Query: 284 NGGKC---IGKSKCKCSKGYQGDLCSKPVCE---PG-CGAHGTCHE---PNKCQCQEGWH 333
NG C + CKC G+ G C V E PG C GTC +CQC +G+
Sbjct: 155 NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
Query: 334 GRHCNKRY 341
G++C+ Y
Sbjct: 215 GQYCDSLY 222
Score = 98.2 bits (243), Expect = 1e-20
Identities = 66/188 (35%), Positives = 83/188 (44%), Gaps = 31/188 (16%)
Query: 186 CRNGGFCN---ERRICECPDGFHGPHCEKAL----CTPRCMNGGLCVT-PGF--CICPPG 235
C NG C + C+C GF G CE + C +GG C+ PG C CP G
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Query: 236 FYGVNCDK--ANCSTT-CFNGGTCFYPG----KCICPPGLEGEQCE--ISKCP-QPCRNG 285
F G CD C+ + C NGGTC G +C C PG EG CE I CP C+NG
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNG 272
Query: 286 GKC---IGKSKCKCSKGYQGDLCSKPVCE-----PGCGAHGTCHEPN---KCQCQEGWHG 334
G C + C+C + G C++ V E C GTC N C C GW G
Sbjct: 273 GVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSG 332
Query: 335 RHCNKRYE 342
C++ +
Sbjct: 333 DDCSENID 340
Score = 98.2 bits (243), Expect = 1e-20
Identities = 67/182 (36%), Positives = 84/182 (46%), Gaps = 33/182 (18%)
Query: 186 CRNGGFCNERR---ICECPDGFHGPHCEK----ALCTPRCMNGGLC---VTPGFCICPPG 235
C N G C+ + +CECP GF G CE+ L P C NGG C V C+C PG
Sbjct: 882 CMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP-CQNGGSCMDGVNTFSCLCLPG 940
Query: 236 FYGVNC--DKANC-STTCFNGGTC---FYPGKCICPPGLEGEQCE--ISKCPQ-PCRNGG 286
F G C D C S C NGGTC C C G +G CE I++C + C NGG
Sbjct: 941 FTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGG 1000
Query: 287 KC---IGKSKCKCSKGYQGDLCSKPVCEPGCGAH-----GTCHE---PNKCQCQEGWHGR 335
C I C C G+ G C + E C +H GTC + +C C G+ G+
Sbjct: 1001 TCVDGINSFSCLCPVGFTGSFCLHEINE--CSSHPCLNEGTCVDGLGTYRCSCPLGYTGK 1058
Query: 336 HC 337
+C
Sbjct: 1059 NC 1060
Score = 96.3 bits (238), Expect = 4e-20
Identities = 63/190 (33%), Positives = 88/190 (46%), Gaps = 30/190 (15%)
Query: 179 QAECPGGCRNGGFCNE---RRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPG---- 228
+ + PG C++GG C C+CP GF G +C+ C P C+NGG C G
Sbjct: 185 ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
Query: 229 FCICPPGFYGVNCDK--ANC-STTCFNGGTC---FYPGKCICPPGLEGEQC--EISKC-- 278
C C PGF G C++ +C + C NGG C C CPP G+ C ++ +C
Sbjct: 245 ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304
Query: 279 -PQPCRNGGKCIGKS---KCKCSKGYQGDLCSKPVCE---PGCGAHGTCHE---PNKCQC 328
P C+NGG C ++ C C G+ GD CS+ + + C TC + C C
Sbjct: 305 QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364
Query: 329 QEGWHGRHCN 338
EG G C+
Sbjct: 365 PEGKAGLLCH 374
Score = 92.4 bits (228), Expect = 6e-19
Identities = 61/190 (32%), Positives = 88/190 (46%), Gaps = 38/190 (20%)
Query: 186 CRNGGFCNERRI---CECPDGFHGPHCEK-------------ALCTPRCMNGGLCVTPG- 228
C+N G C +++ C CP G+ G +C+ L C + G+C+ G
Sbjct: 1072 CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGN 1131
Query: 229 --FCICPPGFYGVNCDKA--NC-STTCFNGGTC--FYPG-KCICPPGLEGEQCE--ISKC 278
+C CP G+ G C++ C S C +G TC F G +C C PG +G CE + +C
Sbjct: 1132 THYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDEC 1191
Query: 279 P-QPCRNGGKCI---GKSKCKCSKGYQGDLCSKPVCEPGCGAH----GTCHE---PNKCQ 327
QPC+NGG CI KC C G +G LC + + + G H G C + C+
Sbjct: 1192 QNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCR 1251
Query: 328 CQEGWHGRHC 337
C G+ G C
Sbjct: 1252 CLPGFAGERC 1261
Score = 90.1 bits (222), Expect = 3e-18
Identities = 60/201 (29%), Positives = 84/201 (41%), Gaps = 33/201 (16%)
Query: 186 CRNGGFCNERRI-----CECPDGFHGPHCEKALCTP-----RCMNGGLCVTPGF----CI 231
C+NGG C + + C C GF G C+ + P C+NGG C C
Sbjct: 73 CQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECT 132
Query: 232 CPPGFYGVNCD--KANCSTTCFNGGTCFYPGK---CICPPGLEGEQCE--ISKCPQP--C 282
C GF G C A S C NG TC C C G G++CE +++C P C
Sbjct: 133 CQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHC 192
Query: 283 RNGGKCI---GKSKCKCSKGYQGDLCSK---PVCEPGCGAHGTCHEPN----KCQCQEGW 332
++GG C+ G +C+C +G+ G C P C GTC + +C C G+
Sbjct: 193 QHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF 252
Query: 333 HGRHCNKRYEASLIHALRPAG 353
G C + + H + G
Sbjct: 253 EGSTCERNIDDCPNHRCQNGG 273
Score = 87.0 bits (214), Expect = 2e-17
Identities = 67/226 (29%), Positives = 88/226 (38%), Gaps = 69/226 (30%)
Query: 186 CRNGGFC-----NERRICECPDGFHGP------------------------------HCE 210
C G C N + IC CP G+ G HCE
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
Query: 211 --KALCTPR------------CMNGGLCVTP--GF-CICPPGFYGVNCDKA--NC-STTC 250
K PR C N C+ GF C+C PGF GV+C+ C S C
Sbjct: 444 CLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
Query: 251 FNGGTC---FYPGKCICPPGLEGEQC--EISKCPQ-PCRNGGKCIGKS---KCKCSKGYQ 301
N G C +C+CPPG G C +I C PC NG KCI +C+C+ G+
Sbjct: 504 VNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFT 563
Query: 302 GDLCSKPV--CEPGCGAHGTCH---EPNKCQCQEGWHGRHCNKRYE 342
G LC + + C+P HG C + C C G+ G C+ + +
Sbjct: 564 GVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQID 609
Score = 86.7 bits (213), Expect = 3e-17
Identities = 57/190 (30%), Positives = 81/190 (42%), Gaps = 29/190 (15%)
Query: 186 CRNGGFCN----ERRICECPDGFHGPHCE--KALCTPRCMNGGLCVTPG---FCICPPGF 236
C NGG C+ + C C GF G C+ A + C NG C T C C GF
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGF 174
Query: 237 YGVNCD----KANCSTTCFNGGTCF-YPG--KCICPPGLEGEQCE---ISKCPQPCRNGG 286
G C+ + + C +GGTC PG +C CP G G+ C+ + P PC NGG
Sbjct: 175 TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGG 234
Query: 287 KCIGKS----KCKCSKGYQGDLCSKPVCE---PGCGAHGTCHE---PNKCQCQEGWHGRH 336
C +C C G++G C + + + C G C + C+C W G+
Sbjct: 235 TCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQF 294
Query: 337 CNKRYEASLI 346
C + + L+
Sbjct: 295 CTEDVDECLL 304
Score = 85.1 bits (209), Expect = 9e-17
Identities = 68/208 (32%), Positives = 85/208 (40%), Gaps = 42/208 (20%)
Query: 168 PQNAIFFKTCQQAEC---PGGCRNGGFCNERR---ICECPDGFHGPHCEK-------ALC 214
PQ F T EC P C+NGG C R C C +G+ G C + A C
Sbjct: 288 PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASC 347
Query: 215 TPRCMNGGLC---VTPGFCICPPGFYGVNC--DKANCSTTCFNGGTCF---YPGK--CIC 264
TP G C V C+CP G G+ C D A S C G C G+ C C
Sbjct: 348 TP----GSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTC 403
Query: 265 PPGLEGEQC--EISKC----PQPCRNGGKCI---GKSKCKCSKGYQGDLCSKPVCE---P 312
P G +G C ++ +C PC + GKC+ G C+C KGY G C + E
Sbjct: 404 PQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSD 463
Query: 313 GCGAHGTCHEP---NKCQCQEGWHGRHC 337
C TC + C C G+ G HC
Sbjct: 464 PCQNDATCLDKIGGFTCLCMPGFKGVHC 491
Score = 84.7 bits (208), Expect = 1e-16
Identities = 63/194 (32%), Positives = 80/194 (41%), Gaps = 37/194 (19%)
Query: 186 CRNGGFCNE---RRICECPDGFHGPHCEKA--LCTPR-CMNGGLCV---TPGFCICPPGF 236
C N G C + C CP G+ G +C+ LC+ C N G CV C+CP G+
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGW 1093
Query: 237 YGVNCDKANCST-------------TCFNGGTCFYPGK---CICPPGLEGEQCE--ISKC 278
G CD N S C + G C G C CP G G CE + +C
Sbjct: 1094 AGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDEC 1153
Query: 279 -PQPCRNGGKC---IGKSKCKCSKGYQGDLCSKPVCE---PGCGAHGTCHE---PNKCQC 328
PC++G C IG +C+C GYQG C V E C GTC + KC C
Sbjct: 1154 ASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 329 QEGWHGRHCNKRYE 342
G G C + +
Sbjct: 1214 PPGTRGLLCEENID 1227
Score = 82.0 bits (201), Expect = 8e-16
Identities = 67/217 (30%), Positives = 86/217 (39%), Gaps = 65/217 (29%)
Query: 186 CRNGGFCNERR---ICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPGF---CICPPGF 236
C+N C ++ C C GF G HCE + C C+N G CV C+CPPGF
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGF 524
Query: 237 YGVNC--DKANCSTT-CFNGGTCF-YPG--KCICPPGLEGEQCE--ISKC-PQPCRNGGK 287
G C D +CS+T C NG C +P +C C G G CE I C P PC +G +
Sbjct: 525 TGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-Q 583
Query: 288 C---IGKSKCKCSKGYQGDLCSKPV------------------------CEPGCGA---- 316
C I C C+ GY G +CS + C+PG
Sbjct: 584 CQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCE 643
Query: 317 ------------HGTCHEP---NKCQCQEGWHGRHCN 338
HG C + C C G+ G+ CN
Sbjct: 644 INFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCN 680
Score = 75.9 bits (185), Expect = 6e-14
Identities = 60/219 (27%), Positives = 82/219 (37%), Gaps = 67/219 (30%)
Query: 186 CRNGGFCNER---RICECPDGFHGPHCEKAL---CTPRCMNGGLC---VTPGFCICPPGF 236
C+NGG C+ C C GF G +C+ + + C+N G C ++ C C +
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPY 825
Query: 237 YGVNCDK--ANCSTT-CFNGGTC-----FYPGKCICPPGLEGEQCEIS------------ 276
G NC A CS C N C F C+C PG +G++C I
Sbjct: 826 TGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNH 885
Query: 277 ------------KCP-----------------QPCRNGGKC---IGKSKCKCSKGYQGDL 304
+CP PC+NGG C + C C G+ GD
Sbjct: 886 GLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDK 945
Query: 305 CSKPVCE---PGCGAHGTCHE---PNKCQCQEGWHGRHC 337
C + E C GTC + C+CQ G+ G HC
Sbjct: 946 CQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHC 984
Score = 75.9 bits (185), Expect = 6e-14
Identities = 58/192 (30%), Positives = 75/192 (39%), Gaps = 43/192 (22%)
Query: 181 ECPGG--CRNGGFCNER---RICECPDGFHGPHCE----KALCTPRCMNGGL-CV---TP 227
+C G C NGG C +R C C GF G CE + L P G L C+
Sbjct: 1228 DCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND 1287
Query: 228 GFCICPPGFYGVNCDK---ANCSTTCFNGGTCFYPGK------CICPPGLEGEQCEISKC 278
C+C F G +C+ C NGGTC C CPPG G +C+ S
Sbjct: 1288 YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCG 1347
Query: 279 PQPCRNGGKCIGKS---KCKCSKGYQGDLCSKPVCEPGCGAH-----GTCHEPNK----- 325
CR G +C+ + +C C S CE GC + G+CH +
Sbjct: 1348 QVKCRKGEQCVHTASGPRCFCP--------SPRDCESGCASSPCQHGGSCHPQRQPPYYS 1399
Query: 326 CQCQEGWHGRHC 337
CQC + G C
Sbjct: 1400 CQCAPPFSGSRC 1411
Score = 73.2 bits (178), Expect = 4e-13
Identities = 60/192 (31%), Positives = 79/192 (41%), Gaps = 31/192 (16%)
Query: 172 IFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHC----EKALCTPRCMNGGLCVTP 227
I F C C G G R C C GF G C ++ P C G C+
Sbjct: 644 INFDDCASNPCIHGICMDGI--NRYSCVCSPGFTGQRCNIDIDECASNP-CRKGATCING 700
Query: 228 --GF-CICPPGFYGVNC-DKAN--CSTTCFNG----GTCFYPGKCICPPGLEGEQCEISK 277
GF CICP G + +C + N S C +G G Y KC+C G G CE+ K
Sbjct: 701 VNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGY--KCLCDAGWVGINCEVDK 758
Query: 278 ---CPQPCRNGGKC---IGKSKCKCSKGYQGDLCSKPVCEPG---CGAHGTCHEP---NK 325
PC+NGG C + +C C KG++G C + E C GTC +
Sbjct: 759 NECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818
Query: 326 CQCQEGWHGRHC 337
C C + G++C
Sbjct: 819 CHCVLPYTGKNC 830
Score = 72.8 bits (177), Expect = 5e-13
Identities = 54/183 (29%), Positives = 74/183 (40%), Gaps = 29/183 (15%)
Query: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKAL---CTPRCMNGGLCV--TPGF-C 230
C +C G + C C G+ G C + + C+N G C+ G+ C
Sbjct: 579 CHHGQCQDGI-------DSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQC 631
Query: 231 ICPPGFYGVNCDKA--NCSTTCFNGGTCF---YPGKCICPPGLEGEQC--EISKC-PQPC 282
C PG GVNC+ +C++ G C C+C PG G++C +I +C PC
Sbjct: 632 NCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPC 691
Query: 283 RNGGKCI---GKSKCKCSKGYQGDLCSKPV--CEPGCGAHGTCH---EPNKCQCQEGWHG 334
R G CI +C C +G C V C HG C KC C GW G
Sbjct: 692 RKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVG 751
Query: 335 RHC 337
+C
Sbjct: 752 INC 754
Score = 66.2 bits (160), Expect = 5e-11
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 39/172 (22%)
Query: 186 CRNGGFCN------ERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGF---CICPPGF 236
C NGG C + IC CP GF G C+ + +C G CV C CP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 237 YGVNCDKANCSTTCFNGGTCFYPGK------CICPPGLEGEQCEISKCPQPCRNGGKCIG 290
+C+ S+ C +GG+C +P + C C P G +CE+ P P C+
Sbjct: 1373 ---DCESGCASSPCQHGGSC-HPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCLS 1427
Query: 291 KSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYE 342
+ Y D VC+ C +H CQ W G C+ E
Sbjct: 1428 Q--------YCADKARDGVCDEACNSHA-------CQ----WDGGDCSLTME 1460
Score = 40.0 bits (92), Expect = 0.003
Identities = 48/182 (26%), Positives = 66/182 (36%), Gaps = 38/182 (20%)
Query: 175 KTCQQAECPGGCRNGGFCNERR-----ICECPDGFHGPHCEKALCTPRCMNGGLCVTPGF 229
+ C+ C++GG C+ +R C+C F G CE P P
Sbjct: 1372 RDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPP-------STPPAT 1424
Query: 230 CI---CPPGFYGVNCDKANCSTTC-FNGGTCFYP-----GKCICP-PGLE--GEQC-EIS 276
C+ C CD+A S C ++GG C C P P + QC E+
Sbjct: 1425 CLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELC 1484
Query: 277 KCPQPCRNGGKCIGKSK-CKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGR 335
+ + +C G SK CK K Y D C+ GC N +C GW G
Sbjct: 1485 NTVECLFDNFECQGNSKTCKYDK-YCADHFKDNHCDQGC---------NSEEC--GWDGL 1532
Query: 336 HC 337
C
Sbjct: 1533 DC 1534
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 99.0 bits (245), Expect = 6e-21
Identities = 62/185 (33%), Positives = 82/185 (44%), Gaps = 24/185 (12%)
Query: 175 KTCQQAECPGGCR--NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCIC 232
K C++A C GC +GG C C C G+ G C++ + P C++G CV P C C
Sbjct: 238 KECKEAVCKQGCNLLHGG-CTVPGECRCSYGWQGRFCDECVPYPGCVHGS-CVEPWQCNC 295
Query: 233 PPGFYGVNCDK----ANCSTTCFNGGTCFYPG----KCICPPGLEGEQCEISK---CPQP 281
+ G+ CDK C NGGTC +C CP G G CE ++ P
Sbjct: 296 ETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNP 355
Query: 282 CRNGGKC---IGKSKCKCSKGYQGDLCSKPVCEPG---CGAHGTCHEP---NKCQCQEGW 332
C NGG C +C C G+ G C+ + E C A GTC + +C C E W
Sbjct: 356 CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQW 415
Query: 333 HGRHC 337
G C
Sbjct: 416 VGATC 420
Score = 97.1 bits (240), Expect = 2e-20
Identities = 63/180 (35%), Positives = 82/180 (45%), Gaps = 28/180 (15%)
Query: 186 CRNGGFCNERRI---CECPDGFHGPHCEKAL--CTPR-CMNGGLC---VTPGFCICPPGF 236
CRNGG C + C CP G+ G C+ C P C + G C V +C C G+
Sbjct: 607 CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 666
Query: 237 YGVNCDKAN--CST-TCFNGGTCFYPG---KCICPPGLEGEQCEISK----CPQPCRNGG 286
G C C TC NGGTC+ G +C CPPG +G C ++K P PC NGG
Sbjct: 667 KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGG 726
Query: 287 KCIGKS---KCKCSKGYQGDLCSKPV--CEP-GCGAHGTCHEP---NKCQCQEGWHGRHC 337
C+G C C G++G C+ C P C G C + +C+C G+ G C
Sbjct: 727 TCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDC 786
Score = 95.5 bits (236), Expect = 7e-20
Identities = 70/215 (32%), Positives = 87/215 (40%), Gaps = 52/215 (24%)
Query: 178 QQAECPGG-CRNGGFCNERRI---CECPDGFHGPHCE--KALCTPR-CMNGGLCVT---P 227
++ EC C +GG C + C CP GF GP CE LC P C NG C
Sbjct: 460 ERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGD 519
Query: 228 GFCICPPGFYGVNCDKAN--------------------------CSTTCFNGGTCF-YPG 260
+C CP F G NC S C G C PG
Sbjct: 520 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG 579
Query: 261 ---KCICPPGLEGEQC--EISKC-PQPCRNGGKCIGK---SKCKCSKGYQGDLC--SKPV 309
CIC G G C I C QPCRNGG CI + +C C G++G+LC +
Sbjct: 580 GNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPND 639
Query: 310 CEPG-CGAHGTCHE---PNKCQCQEGWHGRHCNKR 340
C P C + G C++ C C +GW G+ C+ R
Sbjct: 640 CLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 674
Score = 91.7 bits (226), Expect = 1e-18
Identities = 64/179 (35%), Positives = 84/179 (46%), Gaps = 27/179 (15%)
Query: 186 CRNGGFC----NERRICECPDGFHGPHCEKA--LCTPR-CMNGGLC--VTPGF-CICPPG 235
C NGG C ++ C CPDG+ G +CEKA CT C NGG C V GF C CP G
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
Query: 236 FYGVNC--DKANC-STTCFNGGTCFYP---GKCICPPGLEGEQC--EISKCPQPCRNGGK 287
+ G C D C S C GGTC +CICP G C +++ C C++GG
Sbjct: 377 WSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGT 436
Query: 288 C---IGKSKCKCSKGYQGDLC--SKPVCEPG-CGAHGTCH---EPNKCQCQEGWHGRHC 337
C + +C C +G+ G C + C C + G C + C C +G+ G C
Sbjct: 437 CKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLC 495
Score = 90.1 bits (222), Expect = 3e-18
Identities = 81/289 (28%), Positives = 107/289 (37%), Gaps = 93/289 (32%)
Query: 157 MNSEGNTILQTPQNAIFFKTCQQAE--CPGG-CRNGGFCNERRI---CECPDGFHGPHC- 209
+N+E + T + + C++AE C C NGG C+E C CP G+ GP C
Sbjct: 324 INAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCA 383
Query: 210 ---EKALCTPRCMNGGLCV--TPGF-CICPPGFYGVNC--DKANCSTTCFNGGTC---FY 258
++ P C GG CV GF CICP + G C D +C C +GGTC
Sbjct: 384 LDIDECASNP-CAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVN 442
Query: 259 PGKCICPPGLEGEQCEISK------------------------CPQ-------------- 280
+C+CP G G CE+ + CPQ
Sbjct: 443 GYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLC 502
Query: 281 ---PCRNGGKCI---GKSKCKCSKGYQGDLCSKP-------VCE-------------PG- 313
PCRNG +C G C C + G CS P C PG
Sbjct: 503 EPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGT 562
Query: 314 -----CGAHGTC-HEPN---KCQCQEGWHGRHCNKRYEASLIHALRPAG 353
CG HG C +P C C G+ G +C++ + L R G
Sbjct: 563 AASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGG 611
Score = 89.7 bits (221), Expect = 4e-18
Identities = 56/162 (34%), Positives = 77/162 (47%), Gaps = 18/162 (11%)
Query: 192 CNERRICECPDGFHGPHCEKALCTPRC--MNGGLCVTPGFCICPPGFYGVNCDKANCSTT 249
C++ C DG+ G C++A+C C ++GG C PG C C G+ G CD+
Sbjct: 223 CDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG-CTVPGECRCSYGWQGRFCDECVPYPG 281
Query: 250 CFNGGTCFYPGKCICPPGLEGEQC--EISKC--PQPCRNGGKCIG----KSKCKCSKGYQ 301
C + G+C P +C C G C +++ C PC NGG CI + +C C GY
Sbjct: 282 CVH-GSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYS 340
Query: 302 GDLCSKP--VCEPG-CGAHGTCHE-PN--KCQCQEGWHGRHC 337
G C K C C G+CHE P+ +C C GW G C
Sbjct: 341 GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382
Score = 84.0 bits (206), Expect = 2e-16
Identities = 64/216 (29%), Positives = 85/216 (39%), Gaps = 53/216 (24%)
Query: 176 TCQQA--ECPGGCRNGGFCNE---RRICECPDGFHGPHCE---KALCTPRCMNGGLC--V 225
TCQ +C G C++GG C + C CP GF G HCE + C +GGLC +
Sbjct: 419 TCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDL 478
Query: 226 TPGF-CICPPGFYGVNC--DKANCS-TTCFNGGTCFY---PGKCICPPGLEGEQCEISKC 278
GF C CP GF G C D C + C NG C+ C CP G+ C + +
Sbjct: 479 ADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 538
Query: 279 PQP--------------------------CRNGGKCI----GKSKCKCSKGYQGDLCSKP 308
P P C G+C+ G C C G+ G C +
Sbjct: 539 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN 598
Query: 309 VCE---PGCGAHGTC---HEPNKCQCQEGWHGRHCN 338
+ + C GTC + +C C GW G C+
Sbjct: 599 IDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCD 634
Score = 77.0 bits (188), Expect = 3e-14
Identities = 41/111 (36%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Query: 232 CPPGFYGVNCDKANCSTTCFNGG-TCFYPGKCICPPGLEGEQCEISKCPQPCR--NGGKC 288
C +Y C+K F G TC G C G G++C+ + C Q C +GG C
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG-C 256
Query: 289 IGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
+C+CS G+QG C + V PGC HG+C EP +C C+ W G C+K
Sbjct: 257 TVPGECRCSYGWQGRFCDECVPYPGC-VHGSCVEPWQCNCETNWGGLLCDK 306
Score = 73.9 bits (180), Expect = 2e-13
Identities = 53/159 (33%), Positives = 73/159 (45%), Gaps = 21/159 (13%)
Query: 200 CPDGFHGPHCEKALCTPRCMNGG--LCVTPGFCICPPGFYGVNCDKANCSTTC--FNGGT 255
C + ++ C K C PR G C G C G+ G C +A C C +GG
Sbjct: 198 CDENYYSATCNK-FCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG- 255
Query: 256 CFYPGKCICPPGLEGEQCEISKC-PQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGC 314
C PG+C C G +G C+ +C P P G C+ +C C + G LC K + C
Sbjct: 256 CTVPGECRCSYGWQGRFCD--ECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNY--C 311
Query: 315 GAH------GTC--HEPN--KCQCQEGWHGRHCNKRYEA 343
G+H GTC EP+ +C C +G+ GR+C K A
Sbjct: 312 GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 350
Score = 59.3 bits (142), Expect = 6e-09
Identities = 52/153 (33%), Positives = 64/153 (41%), Gaps = 28/153 (18%)
Query: 183 PGGCRNGGFC---NERRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPGF---CICP 233
P C NGG C C C DG+ G C C P C NGG+CV C C
Sbjct: 719 PNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECA 778
Query: 234 PGFYGVNC----DKANCSTTCFNGGTC---FYPGKCICPPGLEGEQC-EISKCPQPCRNG 285
PGF G +C D+ S+ C G TC +C CPPG G +C E+ + C +
Sbjct: 779 PGFAGPDCRINIDECQ-SSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSR 837
Query: 286 GKCI--GKS------KCKCSKGYQGDLCSKPVC 310
G G S C+C G + CSK C
Sbjct: 838 GTPFPHGSSWVEDCNSCRCLDGRRD--CSKVWC 868
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 99.0 bits (245), Expect = 6e-21
Identities = 62/185 (33%), Positives = 82/185 (44%), Gaps = 24/185 (12%)
Query: 175 KTCQQAECPGGCR--NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCIC 232
K C++A C GC +GG C C C G+ G C++ + P C++G CV P C C
Sbjct: 238 KECKEAVCKQGCNLLHGG-CTVPGECRCSYGWQGRFCDECVPYPGCVHGS-CVEPWQCNC 295
Query: 233 PPGFYGVNCDK----ANCSTTCFNGGTCFYPG----KCICPPGLEGEQCEISK---CPQP 281
+ G+ CDK C NGGTC +C CP G G CE ++ P
Sbjct: 296 ETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNP 355
Query: 282 CRNGGKC---IGKSKCKCSKGYQGDLCSKPVCEPG---CGAHGTCHEP---NKCQCQEGW 332
C NGG C +C C G+ G C+ + E C A GTC + +C C E W
Sbjct: 356 CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQW 415
Query: 333 HGRHC 337
G C
Sbjct: 416 VGATC 420
Score = 98.6 bits (244), Expect = 8e-21
Identities = 70/179 (39%), Positives = 86/179 (48%), Gaps = 27/179 (15%)
Query: 186 CRNGGFC----NERRICECPDGFHGPHCEKA--LCTPR-CMNGGLC--VTPGF-CICPPG 235
C NGG C ++ C CPDG+ G +CEKA CT C NGG C V GF C CP G
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
Query: 236 FYGVNC--DKANC-STTCFNGGTCFYP---GKCICPPGLEGEQCEI--SKCP-QPCRNGG 286
+ G C D C S C GGTC +CICP G C++ ++C +PC N
Sbjct: 377 WSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAF 436
Query: 287 KC---IGKSKCKCSKGYQGDLCSKPV--CEPGCGAHGTCHE---PNKCQCQEGWHGRHC 337
C IG C C G++G C V C C GTC + +C C G+ GRHC
Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHC 495
Score = 97.1 bits (240), Expect = 2e-20
Identities = 63/180 (35%), Positives = 82/180 (45%), Gaps = 28/180 (15%)
Query: 186 CRNGGFCNERRI---CECPDGFHGPHCEKAL--CTPR-CMNGGLC---VTPGFCICPPGF 236
CRNGG C + C CP G+ G C+ C P C + G C V +C C G+
Sbjct: 645 CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704
Query: 237 YGVNCDKAN--CST-TCFNGGTCFYPG---KCICPPGLEGEQCEISK----CPQPCRNGG 286
G C C TC NGGTC+ G +C CPPG +G C ++K P PC NGG
Sbjct: 705 KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGG 764
Query: 287 KCIGKS---KCKCSKGYQGDLCSKPV--CEP-GCGAHGTCHEP---NKCQCQEGWHGRHC 337
C+G C C G++G C+ C P C G C + +C+C G+ G C
Sbjct: 765 TCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDC 824
Score = 95.5 bits (236), Expect = 7e-20
Identities = 70/215 (32%), Positives = 87/215 (40%), Gaps = 52/215 (24%)
Query: 178 QQAECPGG-CRNGGFCNERRI---CECPDGFHGPHCE--KALCTPR-CMNGGLCVT---P 227
++ EC C +GG C + C CP GF GP CE LC P C NG C
Sbjct: 498 ERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGD 557
Query: 228 GFCICPPGFYGVNCDKAN--------------------------CSTTCFNGGTCF-YPG 260
+C CP F G NC S C G C PG
Sbjct: 558 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG 617
Query: 261 ---KCICPPGLEGEQC--EISKC-PQPCRNGGKCIGK---SKCKCSKGYQGDLC--SKPV 309
CIC G G C I C QPCRNGG CI + +C C G++G+LC +
Sbjct: 618 GNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPND 677
Query: 310 CEPG-CGAHGTCHE---PNKCQCQEGWHGRHCNKR 340
C P C + G C++ C C +GW G+ C+ R
Sbjct: 678 CLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSR 712
Score = 89.7 bits (221), Expect = 4e-18
Identities = 56/162 (34%), Positives = 77/162 (47%), Gaps = 18/162 (11%)
Query: 192 CNERRICECPDGFHGPHCEKALCTPRC--MNGGLCVTPGFCICPPGFYGVNCDKANCSTT 249
C++ C DG+ G C++A+C C ++GG C PG C C G+ G CD+
Sbjct: 223 CDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG-CTVPGECRCSYGWQGRFCDECVPYPG 281
Query: 250 CFNGGTCFYPGKCICPPGLEGEQC--EISKC--PQPCRNGGKCIG----KSKCKCSKGYQ 301
C + G+C P +C C G C +++ C PC NGG CI + +C C GY
Sbjct: 282 CVH-GSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYS 340
Query: 302 GDLCSKP--VCEPG-CGAHGTCHE-PN--KCQCQEGWHGRHC 337
G C K C C G+CHE P+ +C C GW G C
Sbjct: 341 GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382
Score = 86.7 bits (213), Expect = 3e-17
Identities = 73/234 (31%), Positives = 97/234 (41%), Gaps = 59/234 (25%)
Query: 176 TCQ--QAECPGG-CRNGGFCNER---RICECPDGFHGPHCEKAL--CTPRCMNGGLC--V 225
TCQ EC G C N C C+C G+ G +C + C +C +GG C +
Sbjct: 419 TCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDL 478
Query: 226 TPGF-CICPPGFYGVNCD--KANC-STTCFNGGTC------FYPGKCICPPGLEGEQCEI 275
G+ C+CP GF G +C+ + C S+ C +GG C F+ C CP G G CE+
Sbjct: 479 VNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH---CHCPQGFSGPLCEV 535
Query: 276 SK--C-PQPCRNGGKCI---GKSKCKCSKGYQGDLCSKP-------VCE----------- 311
C P PCRNG +C G C C + G CS P C
Sbjct: 536 DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGP 595
Query: 312 --PG------CGAHGTC-HEPN---KCQCQEGWHGRHCNKRYEASLIHALRPAG 353
PG CG HG C +P C C G+ G +C++ + L R G
Sbjct: 596 GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGG 649
Score = 83.2 bits (204), Expect = 4e-16
Identities = 61/209 (29%), Positives = 82/209 (39%), Gaps = 51/209 (24%)
Query: 181 ECPGGCRNGGFCNER---RICECPDGFHGPHCE---KALCTPRCMNGGLC--VTPGF-CI 231
+C G C++GG C + C CP GF G HCE + C +GGLC + GF C
Sbjct: 464 DCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCH 523
Query: 232 CPPGFYGVNC--DKANCS-TTCFNGGTCFY---PGKCICPPGLEGEQCEISKCPQP---- 281
CP GF G C D C + C NG C+ C CP G+ C + + P P
Sbjct: 524 CPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGAC 583
Query: 282 ----------------------CRNGGKCI----GKSKCKCSKGYQGDLCSKPVCE---P 312
C G+C+ G C C G+ G C + + +
Sbjct: 584 RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQ 643
Query: 313 GCGAHGTC---HEPNKCQCQEGWHGRHCN 338
C GTC + +C C GW G C+
Sbjct: 644 PCRNGGTCIDEVDAFRCFCPSGWEGELCD 672
Score = 77.0 bits (188), Expect = 3e-14
Identities = 41/111 (36%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Query: 232 CPPGFYGVNCDKANCSTTCFNGG-TCFYPGKCICPPGLEGEQCEISKCPQPCR--NGGKC 288
C +Y C+K F G TC G C G G++C+ + C Q C +GG C
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG-C 256
Query: 289 IGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
+C+CS G+QG C + V PGC HG+C EP +C C+ W G C+K
Sbjct: 257 TVPGECRCSYGWQGRFCDECVPYPGC-VHGSCVEPWQCNCETNWGGLLCDK 306
Score = 73.9 bits (180), Expect = 2e-13
Identities = 53/159 (33%), Positives = 73/159 (45%), Gaps = 21/159 (13%)
Query: 200 CPDGFHGPHCEKALCTPRCMNGG--LCVTPGFCICPPGFYGVNCDKANCSTTC--FNGGT 255
C + ++ C K C PR G C G C G+ G C +A C C +GG
Sbjct: 198 CDENYYSATCNK-FCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGG- 255
Query: 256 CFYPGKCICPPGLEGEQCEISKC-PQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGC 314
C PG+C C G +G C+ +C P P G C+ +C C + G LC K + C
Sbjct: 256 CTVPGECRCSYGWQGRFCD--ECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNY--C 311
Query: 315 GAH------GTC--HEPN--KCQCQEGWHGRHCNKRYEA 343
G+H GTC EP+ +C C +G+ GR+C K A
Sbjct: 312 GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA 350
Score = 59.3 bits (142), Expect = 6e-09
Identities = 52/153 (33%), Positives = 64/153 (41%), Gaps = 28/153 (18%)
Query: 183 PGGCRNGGFC---NERRICECPDGFHGPHCEKAL--CTPR-CMNGGLCVTPGF---CICP 233
P C NGG C C C DG+ G C C P C NGG+CV C C
Sbjct: 757 PNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECA 816
Query: 234 PGFYGVNC----DKANCSTTCFNGGTC---FYPGKCICPPGLEGEQC-EISKCPQPCRNG 285
PGF G +C D+ S+ C G TC +C CPPG G +C E+ + C +
Sbjct: 817 PGFAGPDCRINIDECQ-SSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSR 875
Query: 286 GKCI--GKS------KCKCSKGYQGDLCSKPVC 310
G G S C+C G + CSK C
Sbjct: 876 GTPFPHGSSWVEDCNSCRCLDGRRD--CSKVWC 906
>gi|45593147 EGF-like-domain, multiple 9 [Homo sapiens]
Length = 383
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/173 (35%), Positives = 75/173 (43%), Gaps = 26/173 (15%)
Query: 190 GFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKAN--CS 247
G C C C G+ G HCE+ + P C + G C P CIC G+ G CDK C+
Sbjct: 38 GCCAPDGSCRCDPGWEGLHCERCVRMPGCQH-GTCHQPWQCICHSGWAGKFCDKDEHICT 96
Query: 248 T--TCFNGGTCFYPG----KCICPPGLEGEQCEISKCP-----QPCRNGGKCIGKS---- 292
T C NGG C Y G C+C PG G CE P PCRNGG+C
Sbjct: 97 TQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFAL 156
Query: 293 --KCKCSKGYQGDLCSKPVCE---PGCGAHGTCHE---PNKCQCQEGWHGRHC 337
C+C G+ G C V + C TC + C C EG+ GR C
Sbjct: 157 NFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFC 209
Score = 70.1 bits (170), Expect = 3e-12
Identities = 52/156 (33%), Positives = 63/156 (40%), Gaps = 29/156 (18%)
Query: 186 CRNGGFC----NERRICECPDGFHGPHCEKAL-----CTPRCMNGGLCVTP-GF-----C 230
C+NGG C C C GFHG CE+ C NGG C GF C
Sbjct: 101 CQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTC 160
Query: 231 ICPPGFYGVNCDKA--NC-STTCFNGGTCF---YPGKCICPPGLEGEQCEISK---CPQP 281
C GF G C+ +C C NG TC C+CP G G C I+ +P
Sbjct: 161 RCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRP 220
Query: 282 CRNGGKC---IGKSKCKCSKGYQGDLCS--KPVCEP 312
C+ G +C + C C GY G C PV +P
Sbjct: 221 CQRGARCRDRVHDFDCLCPSGYGGKTCELVLPVPDP 256
Score = 66.6 bits (161), Expect = 3e-11
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Query: 252 NGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNG-GKCIGKSKCKCSKGYQGDLCSKPVC 310
+G C + +C G G+ C C G C C+C G++G C + V
Sbjct: 3 SGCRCLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR 62
Query: 311 EPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
PGC HGTCH+P +C C GW G+ C+K
Sbjct: 63 MPGC-QHGTCHQPWQCICHSGWAGKFCDK 90
Score = 61.6 bits (148), Expect = 1e-09
Identities = 42/118 (35%), Positives = 53/118 (44%), Gaps = 22/118 (18%)
Query: 177 CQQAECPGGCRNGGFCNERR------ICECPDGFHGPHCEKAL--CTPR-CMNGGLC--- 224
C+QA P CRNGG C + + C C GF G CE + C R C NG C
Sbjct: 135 CEQAGSP--CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDG 192
Query: 225 VTPGFCICPPGFYG----VNCDKANCSTTCFNGGTC---FYPGKCICPPGLEGEQCEI 275
+ C+CP GF G +N D S C G C + C+CP G G+ CE+
Sbjct: 193 INRFSCLCPEGFAGRFCTINLDDC-ASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 55.5 bits (132), Expect = 8e-08
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 14/132 (10%)
Query: 220 NGGLCVTPGFCICPPGFYGVNCDKANCSTTC-FNGGTCFYPGKCICPPGLEGEQCEISKC 278
+G C+ +C G G +CS+ C G C G C C PG EG CE
Sbjct: 3 SGCRCLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR 62
Query: 279 PQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQ----------C 328
C++G C +C C G+ G C K E C C +C C
Sbjct: 63 MPGCQHG-TCHQPWQCICHSGWAGKFCDKD--EHICTTQSPCQNGGQCMYDGGGEYHCVC 119
Query: 329 QEGWHGRHCNKR 340
G+HGR C ++
Sbjct: 120 LPGFHGRDCERK 131
>gi|45545431 EGF-like-domain, multiple 9 [Homo sapiens]
Length = 383
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/173 (35%), Positives = 75/173 (43%), Gaps = 26/173 (15%)
Query: 190 GFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKAN--CS 247
G C C C G+ G HCE+ + P C + G C P CIC G+ G CDK C+
Sbjct: 38 GCCAPDGSCRCDPGWEGLHCERCVRMPGCQH-GTCHQPWQCICHSGWAGKFCDKDEHICT 96
Query: 248 T--TCFNGGTCFYPG----KCICPPGLEGEQCEISKCP-----QPCRNGGKCIGKS---- 292
T C NGG C Y G C+C PG G CE P PCRNGG+C
Sbjct: 97 TQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFAL 156
Query: 293 --KCKCSKGYQGDLCSKPVCE---PGCGAHGTCHE---PNKCQCQEGWHGRHC 337
C+C G+ G C V + C TC + C C EG+ GR C
Sbjct: 157 NFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFC 209
Score = 70.1 bits (170), Expect = 3e-12
Identities = 52/156 (33%), Positives = 63/156 (40%), Gaps = 29/156 (18%)
Query: 186 CRNGGFC----NERRICECPDGFHGPHCEKAL-----CTPRCMNGGLCVTP-GF-----C 230
C+NGG C C C GFHG CE+ C NGG C GF C
Sbjct: 101 CQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTC 160
Query: 231 ICPPGFYGVNCDKA--NC-STTCFNGGTCF---YPGKCICPPGLEGEQCEISK---CPQP 281
C GF G C+ +C C NG TC C+CP G G C I+ +P
Sbjct: 161 RCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRP 220
Query: 282 CRNGGKC---IGKSKCKCSKGYQGDLCS--KPVCEP 312
C+ G +C + C C GY G C PV +P
Sbjct: 221 CQRGARCRDRVHDFDCLCPSGYGGKTCELVLPVPDP 256
Score = 66.6 bits (161), Expect = 3e-11
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Query: 252 NGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNG-GKCIGKSKCKCSKGYQGDLCSKPVC 310
+G C + +C G G+ C C G C C+C G++G C + V
Sbjct: 3 SGCRCLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR 62
Query: 311 EPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
PGC HGTCH+P +C C GW G+ C+K
Sbjct: 63 MPGC-QHGTCHQPWQCICHSGWAGKFCDK 90
Score = 61.6 bits (148), Expect = 1e-09
Identities = 42/118 (35%), Positives = 53/118 (44%), Gaps = 22/118 (18%)
Query: 177 CQQAECPGGCRNGGFCNERR------ICECPDGFHGPHCEKAL--CTPR-CMNGGLC--- 224
C+QA P CRNGG C + + C C GF G CE + C R C NG C
Sbjct: 135 CEQAGSP--CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDG 192
Query: 225 VTPGFCICPPGFYG----VNCDKANCSTTCFNGGTC---FYPGKCICPPGLEGEQCEI 275
+ C+CP GF G +N D S C G C + C+CP G G+ CE+
Sbjct: 193 INRFSCLCPEGFAGRFCTINLDDC-ASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 55.5 bits (132), Expect = 8e-08
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 14/132 (10%)
Query: 220 NGGLCVTPGFCICPPGFYGVNCDKANCSTTC-FNGGTCFYPGKCICPPGLEGEQCEISKC 278
+G C+ +C G G +CS+ C G C G C C PG EG CE
Sbjct: 3 SGCRCLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR 62
Query: 279 PQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQ----------C 328
C++G C +C C G+ G C K E C C +C C
Sbjct: 63 MPGCQHG-TCHQPWQCICHSGWAGKFCDKD--EHICTTQSPCQNGGQCMYDGGGEYHCVC 119
Query: 329 QEGWHGRHCNKR 340
G+HGR C ++
Sbjct: 120 LPGFHGRDCERK 131
>gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens]
Length = 4544
Score = 98.2 bits (243), Expect = 1e-20
Identities = 61/183 (33%), Positives = 76/183 (41%), Gaps = 23/183 (12%)
Query: 177 CQQAECPGGCRNGGFC----NERRICECPDGFHGPHCEKALCTPRCMNGGLC-VTPGF-- 229
C+ +C CRNGG C + C CP GF GP C + +C C N C V G
Sbjct: 4231 CELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQP 4290
Query: 230 -CICPPGFYGVNCDKANCSTTCFNGGTCFYPG----KCICPPGLEGEQCEISKCPQPCRN 284
C C PGF G C CS C N GTC +C C EG +CE++KC + C
Sbjct: 4291 QCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRCEVNKCSR-CLE 4349
Query: 285 GGKCIGKSK----CKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNK----CQCQEGWHGRH 336
G + K C C+ G C C C G+C +K CQC G
Sbjct: 4350 GACVVNKQSGDVTCNCTDGRVAPSCL--TCVGHCSNGGSCTMNSKMMPECQCPPHMTGPR 4407
Query: 337 CNK 339
C +
Sbjct: 4408 CEE 4410
Score = 86.3 bits (212), Expect = 4e-17
Identities = 49/157 (31%), Positives = 71/157 (45%), Gaps = 31/157 (19%)
Query: 197 ICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTC 256
+C CP+G + ++ G CV PP C+ CFNGG+C
Sbjct: 4168 VCTCPNG-------------KRLDNGTCVPVPSPTPPPDAPR----PGTCNLQCFNGGSC 4210
Query: 257 FYPG----KCICPPGLEGEQCEISKCPQPCRNGGKCI----GKSKCKCSKGYQGDLCSKP 308
F KC C P G++CE+ +C + CRNGG C G C+C G+ G C++
Sbjct: 4211 FLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQ 4270
Query: 309 VCEPGCGAHGTC-----HEPNKCQCQEGWHGRHCNKR 340
VC C + TC ++P +C+C G+ G C R
Sbjct: 4271 VCAGYCANNSTCTVNQGNQP-QCRCLPGFLGDRCQYR 4306
Score = 37.0 bits (84), Expect = 0.029
Identities = 52/209 (24%), Positives = 67/209 (32%), Gaps = 60/209 (28%)
Query: 176 TCQQAECPGGCRNGGF-CNERRIC-----------ECPDGFHGPHCEKA--LCTPR---- 217
T Q PGGC F C +C +C D CE +C P
Sbjct: 1052 TNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFG 1111
Query: 218 CMNGGLCVTPGFCICPPGFYGVNCDKANC--------STTCFNG-GTCFYPGKCI----- 263
C + C++ + N D+ NC S C N C P K
Sbjct: 1112 CKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPPDKLCDGNDD 1171
Query: 264 CPPGL-EGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPV------------C 310
C G EGE C+ Q N G C C + G +G +CS P+
Sbjct: 1172 CGDGSDEGELCD-----QCSLNNGGC--SHNCSVAPG-EGIVCSCPLGMELGPDNHTCQI 1223
Query: 311 EPGCGAHGTCHEPN-------KCQCQEGW 332
+ C H C + KC C EGW
Sbjct: 1224 QSYCAKHLKCSQKCDQNKFSVKCSCYEGW 1252
Score = 35.0 bits (79), Expect = 0.11
Identities = 40/173 (23%), Positives = 58/173 (33%), Gaps = 40/173 (23%)
Query: 177 CQQAECPGG---CRNGGFCNERRICE----CPDGFHGPHCEKALCTP---RCMNGGLCVT 226
C + +C G C G N IC+ C D +C+ +C P +C N C+
Sbjct: 3369 CPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIP 3428
Query: 227 PGFCI-----CPPGFYGVNCDKANCSTTCFNGGTCFYPGKCI-----------CPPGL-E 269
F C G +C + C+ F C +CI C G E
Sbjct: 3429 GIFRCNGQDNCGDGEDERDCPEVTCAPNQFQ---CSITKRCIPRVWVCDRDNDCVDGSDE 3485
Query: 270 GEQCEISKCPQP---CRNGGKCI-------GKSKCKCSKGYQGDLCSKPVCEP 312
C C C++ G+CI G+ C + C + CEP
Sbjct: 3486 PANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEP 3538
Score = 33.9 bits (76), Expect = 0.25
Identities = 43/170 (25%), Positives = 64/170 (37%), Gaps = 31/170 (18%)
Query: 175 KTCQQAECPGGCRNGGFCNERRICE----CPDGFHGPHCEKALCTPRCMNGGLCVTPGFC 230
+ C ++E C NG R C+ C DG ++ CTPRC G C
Sbjct: 3573 RPCSESEF--SCANGRCIAGRWKCDGDHDCADG-----SDEKDCTPRCDMDQFQCKSGHC 3625
Query: 231 ICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIG 290
I P + CD C +G G + L+ QC + C +P KC G
Sbjct: 3626 I-PLRW---RCD---ADADCMDGSDEEACGTGVRTCPLDEFQCNNTLC-KPL--AWKCDG 3675
Query: 291 KSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEG--WHGRHCN 338
+ C + + C++ VC P + P +C+ W GR C+
Sbjct: 3676 EDDCGDNSDENPEECARFVCPP--------NRPFRCKNDRVCLWIGRQCD 3717
Score = 30.0 bits (66), Expect = 3.6
Identities = 26/99 (26%), Positives = 34/99 (34%), Gaps = 11/99 (11%)
Query: 176 TCQQAECPGG---CRNGGFCNERRICECPDGFHGPHCEKALCT-PRCM-------NGGLC 224
TC CP C +G C+ D E A C P C N G C
Sbjct: 930 TCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRC 989
Query: 225 VTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCI 263
+ + G N D+A CS +C + G+CI
Sbjct: 990 ININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCI 1028
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.481
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,342,171
Number of Sequences: 37866
Number of extensions: 1073304
Number of successful extensions: 7089
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 285
Number of HSP's that attempted gapping in prelim test: 2290
Number of HSP's gapped (non-prelim): 2063
length of query: 379
length of database: 18,247,518
effective HSP length: 104
effective length of query: 275
effective length of database: 14,309,454
effective search space: 3935099850
effective search space used: 3935099850
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.