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Search of human proteins with 110832843
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110832843 TBP-associated factor 4 [Homo sapiens]
(1085 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110832843 TBP-associated factor 4 [Homo sapiens] 2137 0.0
gi|148792970 TAF4b RNA polymerase II, TATA box binding protein (... 352 1e-96
gi|163965366 nascent polypeptide-associated complex alpha subuni... 157 4e-38
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 138 3e-32
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 137 6e-32
gi|160707881 formin 2 [Homo sapiens] 132 2e-30
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 127 4e-29
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 127 4e-29
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 127 4e-29
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 127 4e-29
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 114 7e-25
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 112 2e-24
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 111 3e-24
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 110 9e-24
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 110 9e-24
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 105 2e-22
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 105 2e-22
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 105 2e-22
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 104 4e-22
gi|47132519 Ras association and pleckstrin homology domains 1 is... 103 7e-22
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 103 9e-22
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 103 9e-22
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 103 9e-22
gi|116284392 mucin 2 precursor [Homo sapiens] 103 1e-21
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 102 3e-21
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 102 3e-21
gi|150170670 piccolo isoform 2 [Homo sapiens] 101 3e-21
gi|150378539 piccolo isoform 1 [Homo sapiens] 101 3e-21
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 101 3e-21
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 101 3e-21
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 2137 bits (5537), Expect = 0.0
Identities = 1085/1085 (100%), Positives = 1085/1085 (100%)
Query: 1 MAAGSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGN 60
MAAGSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGN
Sbjct: 1 MAAGSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGN 60
Query: 61 HVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPA 120
HVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPA
Sbjct: 61 HVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPA 120
Query: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP 180
PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP
Sbjct: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP 180
Query: 181 GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT 240
GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT
Sbjct: 181 GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT 240
Query: 241 PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP 300
PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP
Sbjct: 241 PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP 300
Query: 301 AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQT 360
AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQT
Sbjct: 301 AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQT 360
Query: 361 LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT 420
LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT
Sbjct: 361 LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT 420
Query: 421 SGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQA 480
SGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQA
Sbjct: 421 SGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQA 480
Query: 481 HAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATL 540
HAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATL
Sbjct: 481 HAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATL 540
Query: 541 QRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFL 600
QRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFL
Sbjct: 541 QRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFL 600
Query: 601 STLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRS 660
STLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRS
Sbjct: 601 STLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRS 660
Query: 661 LPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPP 720
LPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPP
Sbjct: 661 LPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPP 720
Query: 721 VLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTP 780
VLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTP
Sbjct: 721 VLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTP 780
Query: 781 QQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASM 840
QQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASM
Sbjct: 781 QQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASM 840
Query: 841 AGVNLSEESARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVS 900
AGVNLSEESARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVS
Sbjct: 841 AGVNLSEESARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVS 900
Query: 901 YVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDE 960
YVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDE
Sbjct: 901 YVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDE 960
Query: 961 QEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKV 1020
QEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKV
Sbjct: 961 QEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKV 1020
Query: 1021 DCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQRITRVNLRDLIFCLENERETSHSLLLY 1080
DCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQRITRVNLRDLIFCLENERETSHSLLLY
Sbjct: 1021 DCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQRITRVNLRDLIFCLENERETSHSLLLY 1080
Query: 1081 KAFLK 1085
KAFLK
Sbjct: 1081 KAFLK 1085
>gi|148792970 TAF4b RNA polymerase II, TATA box binding protein
(TBP)-associated factor, 105kDa [Homo sapiens]
Length = 862
Score = 352 bits (903), Expect = 1e-96
Identities = 310/931 (33%), Positives = 420/931 (45%), Gaps = 138/931 (14%)
Query: 210 AAAPAVSLVNNGPAALLPL---PKPAAPGTVIQTPPFVGAAAPPAPAAP--SP------P 258
AA A V PA LP+ P A G V + P V P + P SP
Sbjct: 15 AAVSASGTVTMAPAGALPVRVESTPVALGAVTKAP--VSVCVEPTASQPLRSPVGTLVTK 72
Query: 259 AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318
AP A P + P PAP +A + A PP ++G +P
Sbjct: 73 VAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQ 132
Query: 319 -----AGGPAGVSGQPG-PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372
A + ++ +P P V S + + + A + LA G +T +
Sbjct: 133 QTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIG--TTVVT 190
Query: 373 MVIGPTMQGALPSPAAVPPPAPGTP----TGLPKGAAGAVTQSLSRTPTA---TTSGIRA 425
V P+ ++ P +V PG P T L + GA + + S P ++ ++
Sbjct: 191 TVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGA-SSTPSNEPNLKAENSAAVQI 249
Query: 426 TLTPTVLAPRLPQPPQNPTNIQNF------------QLPPGMVLVRSENGQLL---MIPQ 470
L+PT+L +N +NF Q P V+ QLL + +
Sbjct: 250 NLSPTML--------ENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAE 301
Query: 471 QALAQMQAQAHAQPQTTMAP---------RPATPTSAPPVQISTVQAPGTPIIARQVTP- 520
+ ++ + + PQ + P R P S +Q Q +IA T
Sbjct: 302 EFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTV 361
Query: 521 ------TTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQR 574
TT + ++ + AT R+ VQ L G A G T G
Sbjct: 362 TTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVG-AKAGVVTLHSVGPTAA 420
Query: 575 TVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEA 634
T G TT + +T + + T + L + TA +
Sbjct: 421 T--GGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTL-------------- 464
Query: 635 EDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALT 694
SLPA+ AA S + P S A T
Sbjct: 465 -------------------------SLPAVTFGETSGAAICLPSVK---PVVSSAGTTSD 496
Query: 695 AVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIR 754
V+ + VQ + A PVLS QP G+ + Q LV+QQP
Sbjct: 497 KPVIGTPVQ---------IKLAQPGPVLS--QPA--GIPQAVQVKQLVVQQPSGGNE--- 540
Query: 755 PPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAA 814
QVT Q + + I + P ++K LPG K LS QA+
Sbjct: 541 -KQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSL---QASP 596
Query: 815 AQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELVGTLTRSCKDETFLL 874
QKN++KE FRD+DDINDV SMAGVNL+EE+A ILATNSELVGTL +SCKDE FL
Sbjct: 597 TQKNRIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFLF 656
Query: 875 QAPLQRRILEIGKKHGITELHPDVVSYVSHATQQRLQNLVEKISETAQQKNFSYKDDDRY 934
LQ+RIL+IGKKH ITEL+ D V+ +S ATQ+RL+ L+EK++ AQ + +YK + Y
Sbjct: 657 IGALQKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENY 716
Query: 935 EQASDVRAQLKFFEQLDQIEKQRKDEQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQ 994
SD R+QLKF E+LDQ+EKQRKD +ERE+L++AAKSRS +EDPEQLRLKQKAKE+QQ
Sbjct: 717 ILCSDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQL 776
Query: 995 ELAQMRQRDANLTALAAIGPRKKRKVDCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQR 1054
ELAQ++ RDANLTALAAIGPRKKR ++ SG EG + G+S + +Q R R
Sbjct: 777 ELAQIQHRDANLTALAAIGPRKKRPLE-----SGIEGLKDNLLASGTSSLTATKQLHRPR 831
Query: 1055 ITRVNLRDLIFCLENERETSHSLLLYKAFLK 1085
ITR+ LRDLIFC+E ERE +S LY A LK
Sbjct: 832 ITRICLRDLIFCMEQEREMKYSRALYLALLK 862
Score = 200 bits (508), Expect = 7e-51
Identities = 176/546 (32%), Positives = 249/546 (45%), Gaps = 98/546 (17%)
Query: 363 ASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLS-RTPTAT-- 419
A+ PA+ +AS + GALP P A G T P T S R+P T
Sbjct: 11 AAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLV 70
Query: 420 TSGIRATLTPTVLA-PRLPQPP------QNPTNIQ---NFQLPPGMVLVRSENGQLLMIP 469
T + P V + PRLP P N T IQ N QLPPG VL++S +G L+++
Sbjct: 71 TKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVS 130
Query: 470 QQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIAR-QVTPTTIIKQVS 528
Q Q A+ + + RPA P + V+I TV + +I + VTP + Q+
Sbjct: 131 PQ-----QTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIG 185
Query: 529 QAQTTVQPSATLQRSPGVQPQLVL---GGAAQTASLGTATAVQTGTPQRTVPGATTTSSA 585
T P + +S V +V G T + +++ + P +SA
Sbjct: 186 TTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSA 245
Query: 586 ATET------MENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTS 639
A + +ENVKKCKNFL+ LIKLA SG QS E NVK+LV+ LLD KIEAE+FT
Sbjct: 246 AVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTR 305
Query: 640 RLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPP---TSQATTALTAV 696
+LY EL SSPQP+LVPFLK+S+ ALRQL P+S +FIQQ QQ + TT T+
Sbjct: 306 KLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSP 365
Query: 697 VLSSSVQRTAGKTAATVTSALQPPVLSL---------------------------TQPTQ 729
V++++V + + + V+ A P +S+ T T
Sbjct: 366 VVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTT 425
Query: 730 VGVGKQGQPTPLVIQ----------QPPKP-----GALIRPPQVTLTQTPMVALRQP--- 771
G G PLV QP KP + P VT +T A+ P
Sbjct: 426 AGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVK 485
Query: 772 ---------HNRIMLTTPQQIQLNPLQPVPVV-KPAVLPGTKALSAVSAQAAAAQKNKLK 821
++ ++ TP QI+L QP PV+ +PA +P QA ++ ++
Sbjct: 486 PVVSSAGTTSDKPVIGTPVQIKL--AQPGPVLSQPAGIP----------QAVQVKQLVVQ 533
Query: 822 EPGGGS 827
+P GG+
Sbjct: 534 QPSGGN 539
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 157 bits (398), Expect = 4e-38
Identities = 211/779 (27%), Positives = 288/779 (36%), Gaps = 144/779 (18%)
Query: 66 SPAGAAGAGPAAPA-EGAP---GAAPEPPPAGRARPGGGGPQRP---GPPSPR----RPL 114
SP G GPA P+ +GAP A P P G A P G P PPSP+
Sbjct: 972 SPKG----GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP 1027
Query: 115 VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGP 174
P G + P A P P+GS + P+P A PA P+ GPA + + P P
Sbjct: 1028 FPKGASTPPAATPPSPKGSP-AATPLPKGAPTT----PAATLPSPKGGPATPSLKGAPTP 1082
Query: 175 GPGPGPGPGPGPGKPAG-----PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLP 229
P P GP P+ P AA + L H AP PAA P P
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT------PAATPPSP 1136
Query: 230 KPAAPGTVIQTPPFVGAAAPPAPAAPS-------PPAAPAPAAPAAAPPPPPPAPATLAR 282
K + TPP GA PA PS PP AP PAA PP P AT +
Sbjct: 1137 KGG-----LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS- 1190
Query: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA---PAAGGPAGVSGQPGPGAAAAAPA 339
P G PT A PP + GG A +P A PAA P+ G P A
Sbjct: 1191 ----PKGAPTTPAATPP---SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243
Query: 340 PGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG---PTMQGALPSPAAVPPPAP-- 394
P SPK PP A + PA+T S+ G P +GA P+PA V PP+P
Sbjct: 1244 PAATPPSPKGGPATPPPKG---APTPPAATPPSLKGGLATPPHKGA-PNPAVVTPPSPKG 1299
Query: 395 --------GTPT------GLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPP 440
G PT PKG+ G + TP A T TPT L P
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP-SPKGTPT-LPATTPSSK 1357
Query: 441 QNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPP 500
PT + + P S G M P + + A P+ PTS
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPP---SPKRGPAIPSPK-------GDPTSPAV 1407
Query: 501 VQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTAS 560
+ +S +AP TP+ + A T V +L+++P GG A +S
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV----SLKKAPATSAP--KGGPATPSS 1461
Query: 561 LG--TATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAA 618
G T AV +P+ +S++ + + + SS K+ T +
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
Query: 619 NVKELV---QNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFI 675
+ ++ + LL K A +P+ L+P PA+ +P I
Sbjct: 1522 SRRDPIAPTATLLSKKTPA-----------TLAPKEALIP------PAMTVPSPKKTPAI 1564
Query: 676 QQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQ 735
++ P P+S+ ++ AV S+ K A + L PP ++ P +
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTY------KGAPSPKELLIPPAVTSPSPKEA----- 1613
Query: 736 GQPTPLVIQQP-PKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPV 793
PTP + P P+ G P+ T T P+ TP ++ +P P V
Sbjct: 1614 --PTPPAVTPPSPEKGPATPAPKGTPTSPPV-------------TPSSLKDSPTSPASV 1657
Score = 144 bits (364), Expect = 3e-34
Identities = 272/1153 (23%), Positives = 387/1153 (33%), Gaps = 263/1153 (22%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
PA + PA +P AP PP A P GG P PSP+ P PP+ K
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG----PATPSPKGAPTPPAVTPPSPKG 1021
Query: 127 RP-----------PPEGSAGSCAPVPAAAAVAAGPEPAPAG--PAKPAGPAALAARAGPG 173
P PP + S PAA + G PA P+ GPA + + P
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
Query: 174 PGPGPGPGPGPGPGKPAGPGA-----AQTLNGSAALLNSHHAAAPAVSLVN--------- 219
P P P GP P+ GA A + L H AP
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141
Query: 220 --------NGPAALLPLPK--------PAAPGTVIQTPPF---------------VGAAA 248
PAA P PK AP T TPP AA
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201
Query: 249 PPAP----AAPSPPAAP---------------------APAAPAAAPPPPPPAPATLARP 283
PP+P A PSP AP AP PAA PP P PAT P
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT--PP 1259
Query: 284 PGHPAGPPTAAP-------AVPPPAAAQN----------GGSAGAAP--APAPAAGGPAG 324
P PP A P A PP A N GG A + P AP P A P
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319
Query: 325 VSGQPGPGAAAAAPA-PGVKAESPKRVVQ--------------------AAPPAAQTLAA 363
G PG AP P V SPK PPAA
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379
Query: 364 SGPASTAASMVIGPTM---QGALPSPAAV---PPPAPGTP-------------------- 397
GPA T S GP + +G SPA + P AP TP
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439
Query: 398 ---------TGLPKGAAG-----------AVTQSLSRTPTA------TTSGIRATLTPTV 431
T PKG AVT + P A ++S +A TP
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 432 L-APRLP--------QPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHA 482
+ AP LP + P P++ ++ P +L S+ + P++AL A
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL--SKKTPATLAPKEALI---PPAMT 1554
Query: 483 QPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQR 542
P P TP AP S+ +A P VTP+T S + + P+ T
Sbjct: 1555 VPSPKKTPAIPTPKEAPATP-SSKEASSPP----AVTPSTYKGAPSPKELLIPPAVT-SP 1608
Query: 543 SPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLST 602
SP P + G AT GTP T P T +S + T CK +
Sbjct: 1609 SPKEAP-TPPAVTPPSPEKGPATPAPKGTP--TSPPVTPSSLKDSPTSPASVTCK--MGA 1663
Query: 603 LIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLP 662
+ AS G + + +KE++ A + T + PQ K+S
Sbjct: 1664 TVPQASKGLPAKKGPTALKEVL------VAPAPESTPIITAPTRKGPQ------TKKSSA 1711
Query: 663 ALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAA-TVTSALQPPV 721
+ PD +A + P S A V S + GK A+ + L PP
Sbjct: 1712 TSPPICPDPSA-----KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE 1766
Query: 722 LSLTQPTQVGVGKQGQP------------TPLVIQQPPKPGALIRPPQVTLTQTPMVALR 769
+ P ++ P P+ + P P + P Q L +P + L
Sbjct: 1767 SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE 1826
Query: 770 QPHNRIMLTTPQQIQLNPLQPVPVVKPAV--------LPGTKALSAVSAQAAAAQKNKLK 821
P L + +L PL P + V +P K+ +A Q
Sbjct: 1827 SPSK--PLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKN 1884
Query: 822 EPGGGSFRD-DDDINDVASMAGVNLSEESARILATNSELVGTLTRSCKDETFLLQAPLQR 880
G G+ D D+ + ++ + + A+ LA +E+ DE + +A R
Sbjct: 1885 NKGSGTESDSDESVPELEEQDSTQATTQQAQ-LAAAAEI---------DEEPVSKAKQSR 1934
Query: 881 RILEIGKKHGITELHPDVVSYVSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDV 940
E + +++L V+ V+ T ++ +N++ I++ K+ D Y +
Sbjct: 1935 S--EKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKS---PASDTYIVFGEA 1989
Query: 941 RAQ-LKFFEQLDQIEKQRKDEQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQM 999
+ + L QL EK + + + ++ + QE+ E+ + + E++ EL
Sbjct: 1990 KIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMS 2049
Query: 1000 RQRDANLTALAAI 1012
+ + A+ A+
Sbjct: 2050 QANVSRAKAVRAL 2062
Score = 119 bits (298), Expect = 2e-26
Identities = 215/832 (25%), Positives = 279/832 (33%), Gaps = 126/832 (15%)
Query: 67 PAGAAGAGPAAPAEGA-PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125
P +GA A ++G A P P G + PQ PP+ + AGP P
Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSV----SPQTKRPPTKKGS---AGPDTPIGN 823
Query: 126 LRPP---------PEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA---GPG 173
L P PE S + A + P+P G P+ L+ + P
Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPK 883
Query: 174 PGPGPG----PGPGPGPGKPAGPGAAQTLNGSAALLNSHHA--------AAPAVSLVNNG 221
P P P P GP PA P A L+ +++ A A+P+
Sbjct: 884 ETPTPSVVNLPFPKEGPATPA-PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942
Query: 222 PAALLPLPK--PAAPGTV-IQTPPFVGAAAPPAP----AAPSPPAAPAPAAPAAAPPPPP 274
PAA P PK PA P TPP AA PP+P A PSP AP P PAA PP P
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPP---AATPPSPKGGPATPSPKGAPTP--PAATPPSPK 997
Query: 275 PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334
PAT + P G PT PAV PP+ GS A P P A+ PA P G+
Sbjct: 998 GGPATPS-----PKGAPTP-PAVTPPSPK---GSPAATPFPKGASTPPAATPPSP-KGSP 1047
Query: 335 AAAPAPGVKAESPKRVVQAAP--PAAQTL--AASGPASTAASMVIGPTMQGALPSPAAVP 390
AA P P +P + + PA +L A + PA+T S GP A PSP P
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP----ATPSPKGAP 1103
Query: 391 PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATL-------TPTVLAPRLPQP---- 439
P TP G A + TP AT + L PT A P P
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 440 ---------------PQNPTNIQNFQLPPG-----MVLVRSENGQLLMIPQQALAQMQAQ 479
P +P P G S G L + A
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 480 AHAQPQ---TTMAPR--PATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTV 534
P+ T +P+ P TP + PP S P TP TP +
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPP---SPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280
Query: 535 QPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQ-RTVPGATTTSSAATETMENV 593
P V P GG A + G T P + PG A T
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 594 KKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYL 653
K TL S K T ++ +G S + P P
Sbjct: 1341 PSPKG-TPTLPATTPSSKGGPTTPSS--------KEGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 654 VPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATV 713
P ++P+ + P S A I S ++ P T +T ++ + A T
Sbjct: 1392 GP----AIPSPKG-DPTSPAVIPLSPKKAP------ATPVTREGAATPSKGDLTPPAVTP 1440
Query: 714 TSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHN 773
S + P S + +G PT L PP P P QV + +P A P
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPT-LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 774 RIMLTTPQQIQLNP--LQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEP 823
T P I +P + P + + T L + A A K L P
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Score = 84.7 bits (208), Expect = 4e-16
Identities = 183/777 (23%), Positives = 245/777 (31%), Gaps = 97/777 (12%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPP--PAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124
PA GA P +PA+ +P P +A P + SP PL P +
Sbjct: 536 PASLEGA-PFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKS 594
Query: 125 KLRPPPEGSAGSC--APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGP 182
P P G S +P+ ++ + + AGP AGP ++ P P
Sbjct: 595 LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDS-AGPLLKSSLITPTVAAFPLESA 653
Query: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242
P P T G++ + A+P + G +L P P GT + T P
Sbjct: 654 DPAGVAPT------TAKGTSTYTTT---ASPFLE----GTVSLAPKNHPVKEGT-LTTLP 699
Query: 243 FVGAAAPPAPAAPSPPAAPAPAAP-AAAPPPPPPAPATLARPPGHPAG---------PPT 292
V A+ P APSP AP A AP P P+ P G P G
Sbjct: 700 LVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSA 759
Query: 293 AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352
AP P S A A A + G ++ P P + +P + + P
Sbjct: 760 LAPVASSPKECPTEDS--GASATASSKGTLTYLADSPSPLGVSVSP----QTKRPPTKKG 813
Query: 353 AAPPAAQTLAASGPASTAASMVI---GPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVT 409
+A P S P S + + + QG+ SPA P P +P G P AVT
Sbjct: 814 SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP--TPSAVT 871
Query: 410 QSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIP 469
+P T + T TP+V+ LP P + P Q P + S P
Sbjct: 872 ---PLSPKGVTLPPKETPTPSVV--NLPFPKEGPATPAPKQAPALSMTSSS--------P 918
Query: 470 QQALAQMQAQA-HAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVS 528
++A A + A P AP P P + PP S P TP TP
Sbjct: 919 KKARATPAPKGIPASPSPKGAPTP--PAATPP---SPKGGPATPSPKWAPTPPAATPPSP 973
Query: 529 QAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATE 588
+ P P GG A + G TP P + S AAT
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP------TPPAVTPPSPKGSPAAT- 1026
Query: 589 TMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSS 648
K AS+ +T + L G T L S
Sbjct: 1027 -------------PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT------LPSP 1067
Query: 649 PQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGK 708
P LK P TP S + P P + A T + K
Sbjct: 1068 KGGPATPSLK-GAPTPPAATPPSP---KGGPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123
Query: 709 TAATVTSALQP-PVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVA 767
A T +A P P L P +G PT P G L PP TP
Sbjct: 1124 GAPTTPAATPPSPKGGLATPP-----PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178
Query: 768 LRQPHNRIMLTTPQQIQLNPLQPVPVVKPAV-LPGTKALSAVSAQAAAAQKNKLKEP 823
P + +P+ P P K + P K A + K L P
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235
Score = 63.5 bits (153), Expect = 1e-09
Identities = 187/831 (22%), Positives = 274/831 (32%), Gaps = 115/831 (13%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
P + A P A A+P P P+ A + P P S +P G AP A
Sbjct: 46 PPPCSPAPQQCPLSAANQASPFPSPSTIASTP---LEVPFPQSSSGTALPLGTAPEAPTF 102
Query: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186
P G P+ AA A P AP P+ A LA A P P
Sbjct: 103 LPNLIG-----PPISPAALALASPMIAPTLKGTPSSSAPLALVA-LAPHSVQKSSAFPPN 156
Query: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK-PAAPGTVIQTPPF-- 243
+ P A +GS L++ A + + +N P+ ++P PK +P ++ T P+
Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHC 216
Query: 244 -VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAA 302
A+ + A P P A+P +++ P +P P PP A
Sbjct: 217 VTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAAL 276
Query: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLA 362
+ + S P S Q G P + Q++ + Q L
Sbjct: 277 SLSTQSL------------PVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLG 324
Query: 363 ASGPAS----TAASMVIGPTMQGA-LPSPAAVPPPAPGTPTGLPKGAAG--AVTQSLSRT 415
+GP++ T ++ + + GA PS +V PP P +P A V S+ +
Sbjct: 325 QTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKG 384
Query: 416 P------TATTSGIRATLTPTVLAPRLPQ-PPQNPTNIQNFQLPPGMVLVRSENGQLLMI 468
P T + SG T L+P +P ++ L M + L++
Sbjct: 385 PSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVT 444
Query: 469 PQQALAQMQAQAHAQPQTT--MAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQ 526
+A A P TT +A + P S+ P+ +P ++A +
Sbjct: 445 NPCTIA-------AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV 497
Query: 527 VSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAA 586
+ + V P P VL L T A G P TT
Sbjct: 498 ATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDP 557
Query: 587 TETMENVKKCKNFLSTLIKLASSGKQ---STETAANVKELVQNLLDGKIEAEDFTSRLYR 643
T KN S + SS + S E K L + L GK A TS L
Sbjct: 558 TVLPLVQAAPKN--SPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK-PASSMTSPL-- 612
Query: 644 ELNSSPQPYLV----------PFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTAL 693
+NSS P LK SL +TP AAF P A A
Sbjct: 613 GVNSSASVIKTDSYAGPDSAGPLLKSSL-----ITPTVAAF----------PLESADPA- 656
Query: 694 TAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALI 753
V T K +T T+ P + +G + P K G L
Sbjct: 657 -------GVAPTTAKGTSTYTTTASPFL-------------EGTVSLAPKNHPVKEGTLT 696
Query: 754 RPPQVTLTQTPMVALRQPHNRI--MLTTPQQIQLNPLQPVPVVKPA-VLPGTKALSAVS- 809
P V P N + T ++ P P + PA PGTK + +S
Sbjct: 697 TLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISH 756
Query: 810 ----AQAAAAQKNKLKEPGGGSFRDDDD-----INDVASMAGVNLSEESAR 851
A A++ K E G S + D S GV++S ++ R
Sbjct: 757 TSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807
Score = 53.1 bits (126), Expect = 1e-06
Identities = 139/658 (21%), Positives = 224/658 (34%), Gaps = 100/658 (15%)
Query: 184 PGPGKPAGPGAAQTL---NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT 240
PG P Q L A+L A + +L GP LP P +P Q
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPT----LPPPCSPAPQ-QC 56
Query: 241 PPFVGAAAPPAPA----------APSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290
P A P P+ P P ++ A P P P L PP PA
Sbjct: 57 PLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAAL 116
Query: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRV 350
A+P + P G + +AP A + P +P AES +
Sbjct: 117 ALASPMIAP---TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173
Query: 351 VQAAPPAAQTLAASGPASTAASM--VIGPTMQGALPSPAAVPPPAP---GTPTGLPKGAA 405
+AP +A S P + + + P +G PSP + P TP +
Sbjct: 174 TLSAP-----IAPSEPKTNLNKVPSEVVPNPKGT-PSPPCIVSTVPYHCVTPMASIQSGV 227
Query: 406 GAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQL 465
++ Q+ TPT T + + T ++ L PQNP ++
Sbjct: 228 ASLPQT---TPTTTLAIASPQVKDTTISSVLIS-PQNPGSLS------------------ 265
Query: 466 LMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAP--PVQISTVQAP------GTPIIARQ 517
L P A + + P T + + A P + P P+ + + AP G+ + Q
Sbjct: 266 LKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQ 325
Query: 518 VTPTTI----IKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQ 573
P+ + +K +S ++ S QRS V P L A++ V +
Sbjct: 326 TGPSALSDPTVKTISVDHSSTGASYPSQRS--VIPPLPSRNEVVPATVAAFPVVAPSVDK 383
Query: 574 RTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIE 633
G +T SS ++ +F +L S +S+ A LV + +
Sbjct: 384 ----GPSTISSITCSPSGSLNVATSF--SLSPTTSLILKSSPNATYHYPLVAQMPVSSVG 437
Query: 634 AEDFTSRLYRELNSSPQPYLVPFLKRSLP----ALRQLTPDSAAFIQQSQQQPPPPTSQA 689
+ ++P S P + + P S A + + P P++Q
Sbjct: 438 TTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV 497
Query: 690 TTALTAVV------------LSSS--VQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQ 735
T L V L SS V+ K TV ++L+ S P Q G+ +
Sbjct: 498 ATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS---PAQAGLTTK 554
Query: 736 GQPTPL-VIQQPPKPGALIR----PPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPL 788
PT L ++Q PK + P++ L+ +A + + + P +PL
Sbjct: 555 KDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPL 612
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 138 bits (347), Expect = 3e-32
Identities = 163/567 (28%), Positives = 211/567 (37%), Gaps = 66/567 (11%)
Query: 45 PRTPE-VRAAAAGALGNHVVSGSPAGAAGAGPAAPAEG--------APGAAPEPPPAGRA 95
P TP A + A G V G P A A P P EG + + EP PA R
Sbjct: 160 PGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 96 RPG-GGGPQRPGPPSPRRPLVP-AGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA 153
RP GGG QRP S P + PA R P A P P P+
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277
Query: 154 PAGP-AKPA-GPAALAARAGPGPGPGPGPGPGPG----PGKPAGPGAAQTLNGSAALLNS 207
P A PA GP + + A P P P P P P PA P + T + + L +
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337
Query: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267
H+ P+ P + L P P AP + PP +PPA SP A P+P AP
Sbjct: 338 THSFLPSP------PLSPLATPPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPN 390
Query: 268 A-------APPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG 320
A AP PPP+P A P PA PP + A PP A + + P+P A
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449
Query: 321 GPAGVSGQPGPGAAAAAPAPGVKAESP---------KRVVQAAPPAAQTLAASGPASTAA 371
P S P P A AP ++ P +QA P + P S +A
Sbjct: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 372 SMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPT----ATTSGIRATL 427
S+ + P A P P A P A P A Q+ R PT + SG R TL
Sbjct: 510 SLPMSPL---ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 566
Query: 428 TPTVLAPRLPQPP-QNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQT 486
LAP P PP ++P++ + G + + L + + A A P
Sbjct: 567 ---ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR-GYDSGPEGGAAASPPPDA 622
Query: 487 TMAP-RPATPTSAPPVQISTVQAPGTPIIARQVTP-------TTIIKQVSQAQTTVQPSA 538
+A PA + P ++ APG P+ T TI + T P A
Sbjct: 623 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 682
Query: 539 TLQRSPGVQPQLVLGGAAQTASLGTAT 565
PG P G AA A G ++
Sbjct: 683 L---DPGPSPGTSGGKAAAGAGAGASS 706
Score = 115 bits (289), Expect = 2e-25
Identities = 157/567 (27%), Positives = 208/567 (36%), Gaps = 139/567 (24%)
Query: 54 AAGALGNHVVSGSPAGAAGA--GPAAPAEG--------APGAAPEPPPAGRARPG----- 98
AAGA+G ++ G GA +AP G A G PPA PG
Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSP 108
Query: 99 --GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSA--------------GSCAPVPA 142
G RPGP + + A K P+ SA G+ +P A
Sbjct: 109 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 168
Query: 143 AAAVAAG-----PEPAPA--------GPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP 189
+ AAG P PAP+ GP K A+ + P P P G G +P
Sbjct: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228
Query: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA----------------ALLPLPKPAA 233
A+++L+ SA L+S + P+ PA + P K AA
Sbjct: 229 ----ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284
Query: 234 P--GTVIQTP-PFVGAAAPPAPAA-------PSPPAAP---------------------- 261
P G + +P +APP+P+A PSPPA P
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 262 APAAPAAAPPP-PPPAPA--TLARPPGHPAGPPTAAPAVPPP----AAAQNGGSAGAAPA 314
P +P A PPP PPA A L PP PA PP + A P P A A + A +P
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 315 PAPAAGGPAGVSGQP--GPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372
P+P P P P A + AP A P +V + P + ++ P A
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464
Query: 373 MVIGPTMQGALPSPAAVP----PP---APGTPTGLPKGAAGAVTQSLSRTPTATTSGIRA 425
+ P +Q A P P A P PP P P P A + + SL +P AT
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP---P 521
Query: 426 TLTPTVLAPRL---PQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHA 482
P + AP L P PP +PT +Q + PP S +G P+ LA
Sbjct: 522 QAPPVLAAPLLQVPPSPPASPT-LQAPRRPPTPGPDTSVSG-----PRLTLA-------- 567
Query: 483 QPQTTMAPRPATPTSAPPVQISTVQAP 509
+AP P P S P ST+ P
Sbjct: 568 -----LAPGPPPPPSRSP--SSTLSGP 587
Score = 113 bits (282), Expect = 1e-24
Identities = 150/522 (28%), Positives = 191/522 (36%), Gaps = 65/522 (12%)
Query: 82 APGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAG----PAPPAAKLRPPPEGSAGSC 137
A A PA RA PG P+ PG P P P+ PA A A +P E + G
Sbjct: 8 AKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 138 APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG---- 193
+A AGP PA G A A+ PGP PG G +P G
Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAK-NTSPGPVSSPGRASGTTRPGPLGQKGL 125
Query: 194 ---AAQTL-NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
A +T+ G A A + +GP P P A T VG P
Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE--VGLPRP 183
Query: 250 PAPAAPSPPA-APAPAAPAAAP-PPPPPAPATLARPPG-----HPAGPPTAAPAVPPPAA 302
A P PP P + +A+ P+PA RP PA ++ A P +
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 303 AQNGGSAGAAP-APA-PAAGGPAGVSG----QPGPGAAAAAPAPGVKAESPKRVVQ---- 352
A++G SA P APA P+ P G+ Q P AAPA G + SP
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP 303
Query: 353 ---AAPPAAQTLAA--SGPASTAASMVIGPTMQGA---LPSP-----AAVPPPAPGTPTG 399
+APP+ QTL + + P S A + + PT+Q LPSP A PP AP
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 363
Query: 400 LPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLP------- 452
P A + S +P AT S P LA L Q P +P Q P
Sbjct: 364 PPLQAPPSPPASPPLSPLATPS----PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 453 ---PGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAP 509
P L P Q A P T P+ P +APP+Q++
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 510 GTPIIAR---QVTPTTIIKQVSQAQTTVQPSATLQRSPGVQP 548
P +A Q P+ QA PSA+L SP P
Sbjct: 480 APPALATPPLQALPSPPASFPGQA--PFSPSASLPMSPLATP 519
Score = 108 bits (269), Expect = 4e-23
Identities = 115/374 (30%), Positives = 143/374 (38%), Gaps = 36/374 (9%)
Query: 76 AAPAEGAPGAAPEPPPAGRARPGGGGPQRP-GPPSPRRPLVPA----------GPAPPA- 123
A P AP A PP P P P PSP+ P A P+PP
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410
Query: 124 AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG 183
A PP A P+ A + P P+ PA P + P P P P
Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 470
Query: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
KP L S A+ P + + P+A LP+ A P Q PP
Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMSPLATPPP--QAPPV 526
Query: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA-----TLARPPGHPAGPPTAAPAVP 298
+ AAP PSPPA+P AP P P P TLA PG P PP+ +P+
Sbjct: 527 L--AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG-PPPPPSRSPSST 583
Query: 299 PPAAAQNGGSAGAAPAPAPAAG---GP-AGVSGQPGPGA--AAAAPAPGVKAESPKRVVQ 352
G S+ A P G GP G + P P A AA PA + +P +
Sbjct: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 643
Query: 353 AAPPAAQTL-AASGPASTAASMVIGPT--MQGALPSPAAVPP-PAPGTPTGLPKGAAGAV 408
AP A A+GP S I T + A P+P A+ P P+PGT G K AAGA
Sbjct: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAG 701
Query: 409 TQSLSRTPTATTSG 422
+ SR+P G
Sbjct: 702 AGASSRSPKQARLG 715
Score = 80.9 bits (198), Expect = 6e-15
Identities = 96/339 (28%), Positives = 122/339 (35%), Gaps = 49/339 (14%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEP---PPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA 123
P + P +P+ P AP P PP A+P PQ PP+ P + A P+PPA
Sbjct: 443 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP---PQ--APPALATPPLQALPSPPA 497
Query: 124 AKLRPPPEGSAGS------CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG 177
+ P + S P P A V A P P+ PA P A R P PGP
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPD 556
Query: 178 PG-PGP------GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL--VNNGPAALLPL 228
GP PGP P + TL+G +S A + L ++GP
Sbjct: 557 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE----- 611
Query: 229 PKPAAPGTVIQTPPFVGAAAPPAPAA----PSPPAA--PAPAAPAAAPPPPPPAPATLAR 282
G +PP A PAA P+PP A AP AP PP P A
Sbjct: 612 ------GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC 665
Query: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGV 342
GP +A PA P A G S G + A A G S P P +
Sbjct: 666 TIYETEGPESATPA---PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 722
Query: 343 KAESPKRVVQ-----AAPPAAQTLAASGPASTAASMVIG 376
+A + ++ AA A + GP V G
Sbjct: 723 QASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG 761
Score = 59.7 bits (143), Expect = 1e-08
Identities = 128/582 (21%), Positives = 179/582 (30%), Gaps = 137/582 (23%)
Query: 265 APAAAPPPPPPAPATLA-RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323
A AAA P AP L RPPG P PP PA A G+ G P A AGG
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGA--AGAVGRKPL-AERAGGIG 66
Query: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383
G + + ++AP A T + PAS P +
Sbjct: 67 GAT-----------------------IPESAPRAGPTRTSRPPASGRGERA--PPAKNTS 101
Query: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
P P + P A GT P G G+R + TV + + P+
Sbjct: 102 PGPVSSPGRASGTTRPGPLGQ----------------KGLRISAEETVARGKATEAPKRS 145
Query: 444 TNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQ---PQTTMAPRPATPTSAPP 500
+ R +G P A+A+ A + P+ + RP PT P
Sbjct: 146 ALSAGAR--------RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197
Query: 501 VQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTAS 560
+S+ + +T +PS +R P GG + AS
Sbjct: 198 KSVSS----------------------ASEHSTTEPSPAARRRPSAG-----GGLQRPAS 230
Query: 561 LG-TATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAAN 619
+++A +P R+ P A T A + K G Q+
Sbjct: 231 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK--------------GLQALRPP-- 274
Query: 620 VKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQ 679
+ + +A L ++P P P +P + +Q
Sbjct: 275 ------QVTPPRKDAAPALGPLSSSPLATPSPSAPP------------SPSAPPSLQTLP 316
Query: 680 QQPPPPTSQATTALTAVVLSS--SVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQ 737
P P SQATT+L + L + S + + PP L+L P Q
Sbjct: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL-PPLQAPPSPPAS 375
Query: 738 P--TPLVIQQPPKPGAL--------IRPPQVTLTQTPMVALRQPHNRIMLTTPQQ----I 783
P +PL P P AL PP Q P P T P Q +
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435
Query: 784 QLNPLQ--PVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEP 823
PLQ P P P + P AA K P
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/184 (32%), Positives = 64/184 (34%), Gaps = 33/184 (17%)
Query: 38 AHHHHLAPRTPE-VRAAAAGALGNHVVSGSPAGAAGA--------GPAAPA--EGAPGAA 86
A H A TPE +R +G G S P A GPA P GAPGA
Sbjct: 590 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 649
Query: 87 -PEPPPAGRARPGGGGP--QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAA 143
P PP G G + GP S A PAP A P P S G A A
Sbjct: 650 LPWPPATGPGSADGLCTIYETEGPES-------ATPAPGALDPGPSPGTSGGKAAAGAGA 702
Query: 144 AAVAAGPEPAPAGPAKPAGPAA------------LAARAGPGPGPGPGPGPGPGPGKPAG 191
A + P+ A G A LAA G G G GPG G G G
Sbjct: 703 GASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 762
Query: 192 PGAA 195
AA
Sbjct: 763 ARAA 766
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 137 bits (345), Expect = 6e-32
Identities = 168/600 (28%), Positives = 218/600 (36%), Gaps = 102/600 (17%)
Query: 45 PRTPE-VRAAAAGALGNHVVSGSPAGAAGAGPAAPAEG--------APGAAPEPPPAGRA 95
P TP A + A G V G P A A P P EG + + EP PA R
Sbjct: 169 PGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 96 RPGGGG-------------------PQRPGPPSPRRPLVPAGPAPPAAK----LRPP--- 129
RP GG P R GP + P PA P+ P K LRPP
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
Query: 130 -----------PEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178
P S+ P P+AA + P P PA P + A P P P
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAP---PTLPATPHSSSLTCQLATPLPLAPP 343
Query: 179 GPGPGPG----PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234
P P P PA P + T + + L + H+ P+ P + L P P AP
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP------PLSPLATPPPQAP 397
Query: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAA-------APPPPPPAPATLARPPGHP 287
+ PP +PPA SP A P+P AP A AP PPP+P A P P
Sbjct: 398 -PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPP 455
Query: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347
A PP + A PP A + + P+P A P S P P A AP ++ P
Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
Query: 348 ---------KRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPT 398
+QA P + P S +AS+ + P A P P A P A
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL---ATPPPQAPPVLAAPLLQ 572
Query: 399 GLPKGAAGAVTQSLSRTPT----ATTSGIRATLTPTVLAPRLPQPP-QNPTNIQNFQLPP 453
P A Q+ R PT + SG R TL LAP P PP ++P++ +
Sbjct: 573 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL---ALAPGPPPPPSRSPSSTLSGPDLA 629
Query: 454 GMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAP-RPATPTSAPPVQISTVQAPGTP 512
G + + L + + A A P +A PA + P ++ APG P
Sbjct: 630 GHSSSATSTPEELR-GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688
Query: 513 IIARQVTP-------TTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTAT 565
+ T TI + T P A PG P G AA A G ++
Sbjct: 689 LPWPPATGPGSADGLCTIYETEGPESATPAPGAL---DPGPSPGTSGGKAAAGAGAGASS 745
Score = 114 bits (286), Expect = 4e-25
Identities = 153/559 (27%), Positives = 198/559 (35%), Gaps = 95/559 (16%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP 107
P V AA LG AGA G P A G G A P A RA P
Sbjct: 37 PPVTPAALRVLG-------AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 108 PSPRRPLVPAGPAPPAAK----------------LRPPPEG------------SAGSCAP 139
P+ R P G P AK RP P G + G
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 140 VPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPG-PGPGPGPGKPAGPGAAQTL 198
P +A++AG +GP P P+ AR G G P P P +P P
Sbjct: 150 APKRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRK 207
Query: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA-----PGTVIQTPPFVGAAAPPAPA 253
+ S+A S H+ P+A L +PA+ T + +P G +A P
Sbjct: 208 SVSSA---SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 254 APSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP-AVPPPAAAQNGGSAGAA 312
AP+ P+ P P A PP P A P GP +++P A P P+AA A
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPA---LGPLSSSPLATPSPSAALQ----SQA 317
Query: 313 PAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA--SGPASTA 370
P PA + ++ Q A P+P +APP+ QTL + + P S A
Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPPSP------------SAPPSLQTLPSPPATPPSQA 365
Query: 371 ASMVIGPTMQGA---LPSP-----AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSG 422
+ + PT+Q LPSP A PP AP P A + S +P AT S
Sbjct: 366 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS- 424
Query: 423 IRATLTPTVLAPRLPQPPQNPTNIQNFQLP----------PGMVLVRSENGQLLMIPQQA 472
P LA L Q P +P Q P P L P Q
Sbjct: 425 ---PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481
Query: 473 LAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIAR---QVTPTTIIKQVSQ 529
A P T P+ P +APP+Q++ P +A Q P+ Q
Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541
Query: 530 AQTTVQPSATLQRSPGVQP 548
A PSA+L SP P
Sbjct: 542 A--PFSPSASLPMSPLATP 558
Score = 108 bits (269), Expect = 4e-23
Identities = 115/374 (30%), Positives = 143/374 (38%), Gaps = 36/374 (9%)
Query: 76 AAPAEGAPGAAPEPPPAGRARPGGGGPQRP-GPPSPRRPLVPA----------GPAPPA- 123
A P AP A PP P P P PSP+ P A P+PP
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
Query: 124 AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG 183
A PP A P+ A + P P+ PA P + P P P P
Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
KP L S A+ P + + P+A LP+ A P Q PP
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMSPLATPPP--QAPPV 565
Query: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA-----TLARPPGHPAGPPTAAPAVP 298
+ AAP PSPPA+P AP P P P TLA PG P PP+ +P+
Sbjct: 566 L--AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG-PPPPPSRSPSST 622
Query: 299 PPAAAQNGGSAGAAPAPAPAAG---GP-AGVSGQPGPGA--AAAAPAPGVKAESPKRVVQ 352
G S+ A P G GP G + P P A AA PA + +P +
Sbjct: 623 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 682
Query: 353 AAPPAAQTL-AASGPASTAASMVIGPT--MQGALPSPAAVPP-PAPGTPTGLPKGAAGAV 408
AP A A+GP S I T + A P+P A+ P P+PGT G K AAGA
Sbjct: 683 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAG 740
Query: 409 TQSLSRTPTATTSG 422
+ SR+P G
Sbjct: 741 AGASSRSPKQARLG 754
Score = 107 bits (266), Expect = 8e-23
Identities = 146/518 (28%), Positives = 183/518 (35%), Gaps = 79/518 (15%)
Query: 82 APGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVP 141
A A PA RA PG P+ PG P P P+ PAA LR G+AG+ P
Sbjct: 8 AKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVT------PAA-LR--VLGAAGAVGRKP 57
Query: 142 AAAAV-----AAGPEPAP-AGPAKPAG-----PAALAARAGPGPGPGPGPGPGPGPGKPA 190
A A PE AP AGP + AG PA+ +G G P PGP
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117
Query: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250
G + T G L A V G A P + G T + P
Sbjct: 118 GRASGTTRPGP---LGQKGLRISAEETVARGKATEAPKRSALSAGARRDT-------SGP 167
Query: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP------------GHPAGPPTAAPAVP 298
P PSP A A P PAP+ RPP H P+ A
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Query: 299 PPAA------AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352
P A A S+ A P +PA GP S + P A A P K R Q
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 353 AAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT--------------PT 398
PP A GP S +S + P+ AL S A PP P T P
Sbjct: 285 VTPPRKDAAPALGPLS--SSPLATPSPSAALQSQA--PPTLPATPHSSSLTCQLATPLPL 340
Query: 399 GLPKGAAGAVTQSLSRTPTATTSGIRATL-TPTVLAPR--LPQPPQNPTNIQNFQLPPGM 455
P +A Q+L P S +L +PT+ A LP PP +P Q PP +
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
Query: 456 VL--VRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPI 513
L +++ P LA QA + P +P +PPVQ + P +P
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-APFSPPASPP 459
Query: 514 IARQVTPTTIIKQVSQA---QTTVQPSATLQRSPGVQP 548
++ TP + A Q P A+ SP P
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497
Score = 80.9 bits (198), Expect = 6e-15
Identities = 96/339 (28%), Positives = 122/339 (35%), Gaps = 49/339 (14%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEP---PPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA 123
P + P +P+ P AP P PP A+P PQ PP+ P + A P+PPA
Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP---PQ--APPALATPPLQALPSPPA 536
Query: 124 AKLRPPPEGSAGS------CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG 177
+ P + S P P A V A P P+ PA P A R P PGP
Sbjct: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPD 595
Query: 178 PG-PGP------GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL--VNNGPAALLPL 228
GP PGP P + TL+G +S A + L ++GP
Sbjct: 596 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE----- 650
Query: 229 PKPAAPGTVIQTPPFVGAAAPPAPAA----PSPPAA--PAPAAPAAAPPPPPPAPATLAR 282
G +PP A PAA P+PP A AP AP PP P A
Sbjct: 651 ------GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC 704
Query: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGV 342
GP +A PA P A G S G + A A G S P P +
Sbjct: 705 TIYETEGPESATPA---PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 761
Query: 343 KAESPKRVVQ-----AAPPAAQTLAASGPASTAASMVIG 376
+A + ++ AA A + GP V G
Sbjct: 762 QASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG 800
Score = 70.1 bits (170), Expect = 1e-11
Identities = 138/595 (23%), Positives = 193/595 (32%), Gaps = 124/595 (20%)
Query: 265 APAAAPPPPPPAPATLA-RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323
A AAA P AP L RPPG P PP PA A + G+AGA P A
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPA-----ALRVLGAAGAV-GRKPLAERAG 63
Query: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383
G+ G P +A A P A + R + PPA SG A P +
Sbjct: 64 GIGGATIPESAPRA-GPTRSAGTSSRNPASRPPA------SGRGERA------PPAKNTS 110
Query: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
P P + P A GT P G G+R + TV + + P+
Sbjct: 111 PGPVSSPGRASGTTRPGPLGQ----------------KGLRISAEETVARGKATEAPKRS 154
Query: 444 TNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQ---PQTTMAPRPATPTSAPP 500
+ R +G P A+A+ A + P+ + RP PT P
Sbjct: 155 ALSAGAR--------RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 501 VQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTAS 560
+S+ + +T +PS +R P GG + AS
Sbjct: 207 KSVSS----------------------ASEHSTTEPSPAARRRPSAG-----GGLQRPAS 239
Query: 561 LG-TATAVQTGTPQRTVPGATTTSSAATETMENVKKC-------------KNFLSTLIKL 606
+++A +P R+ P A T A + K K+ L L
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 607 ASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQ 666
+SS + +A ++ L + T +L ++P P P
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL-----ATPLPLAPP----------- 343
Query: 667 LTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSS--SVQRTAGKTAATVTSALQPPVLSL 724
+P + +Q P P SQATT+L + L + S + + PP L+L
Sbjct: 344 -SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402
Query: 725 TQPTQVGVGKQGQP--TPLVIQQPPKPGAL--------IRPPQVTLTQTPMVALRQPHNR 774
P Q P +PL P P AL PP Q P P
Sbjct: 403 -PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461
Query: 775 IMLTTPQQ----IQLNPLQ--PVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEP 823
T P Q + PLQ P P P + P AA K P
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/184 (32%), Positives = 64/184 (34%), Gaps = 33/184 (17%)
Query: 38 AHHHHLAPRTPE-VRAAAAGALGNHVVSGSPAGAAGA--------GPAAPA--EGAPGAA 86
A H A TPE +R +G G S P A GPA P GAPGA
Sbjct: 629 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688
Query: 87 -PEPPPAGRARPGGGGP--QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAA 143
P PP G G + GP S A PAP A P P S G A A
Sbjct: 689 LPWPPATGPGSADGLCTIYETEGPES-------ATPAPGALDPGPSPGTSGGKAAAGAGA 741
Query: 144 AAVAAGPEPAPAGPAKPAGPAA------------LAARAGPGPGPGPGPGPGPGPGKPAG 191
A + P+ A G A LAA G G G GPG G G G
Sbjct: 742 GASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 801
Query: 192 PGAA 195
AA
Sbjct: 802 ARAA 805
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 132 bits (331), Expect = 2e-30
Identities = 113/354 (31%), Positives = 121/354 (34%), Gaps = 43/354 (12%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
P AG P P GA G P PP PG G P P PP P + P P P A
Sbjct: 914 PLPGAGIPPPPPLPGA-GILPLPP-----LPGAGIP--PPPPLPGAAIPPPPPLPGAGIP 965
Query: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG---PGPGPG 183
PPP AG P P A P P P P P A P P PG P P P
Sbjct: 966 LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1025
Query: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
PG G P P L G+ P L P A +P P P + PP
Sbjct: 1026 PGAGIPPPP----PLPGA--------GIPPPPPL----PGAGIPPPPPLPGAGIPPPPPL 1069
Query: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP------GHPAGPPTAAPAV 297
GA PP P P P P P A PPPPP P PP G P PP +
Sbjct: 1070 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGI 1129
Query: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQ--------PGPGAAAAAPAPGVKAESPKR 349
PPP G P P P + G PG G P PGV P
Sbjct: 1130 PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1189
Query: 350 VVQAAPPAAQTLAASG--PASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401
+ P L +G P M I P LP P PP P P P
Sbjct: 1190 LPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGP 1243
Score = 120 bits (300), Expect = 9e-27
Identities = 135/489 (27%), Positives = 162/489 (33%), Gaps = 88/489 (17%)
Query: 87 PEPPP-----AGRARPGGGGPQR-----------------------PGPPSPRRPLVPAG 118
P PPP AG+ +PG P P PP P +
Sbjct: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP-PLPCTESSS 868
Query: 119 PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178
P + PPP G P + A+ P P P P L P P P P
Sbjct: 869 SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQ-PPPLQGTEMLPPPPPPLPGAGIPPPPPLP 927
Query: 179 GPG-----PGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA 233
G G P PG G P P L G+A P L P A +PLP P
Sbjct: 928 GAGILPLPPLPGAGIPPPP----PLPGAAI--------PPPPPL----PGAGIPLPPPLP 971
Query: 234 PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP------GHP 287
+ PP GA PP P P P P P A PPPPP P PP G P
Sbjct: 972 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1031
Query: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347
PP +PPP G P P P AG P PG G P PG P
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPP 1088
Query: 348 KRVVQAAPPAAQTLAASG----PASTAASMVIGPTMQGA-LPSP-----AAVPPPAP--- 394
+ A P L G P A + P + GA +P P A +PPP P
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPR 1148
Query: 395 -GTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPP 453
G P P AG P G P + +P PP P +PP
Sbjct: 1149 VGIPPPPPLPGAGI-------PPPPPLPGAGIPPPPPLPGVGIPPPPPLP----GVGIPP 1197
Query: 454 GMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPV--QISTVQAPGT 511
L + +P + A P T + P P P S PP+ Q+ + P T
Sbjct: 1198 PPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP-T 1256
Query: 512 PIIARQVTP 520
P + + P
Sbjct: 1257 PQVCGFLPP 1265
Score = 68.9 bits (167), Expect = 2e-11
Identities = 65/209 (31%), Positives = 69/209 (33%), Gaps = 53/209 (25%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
P AG P P GA P PPP PG G P P PP PR + P P P A +
Sbjct: 1112 PLPGAGIPPPPPLPGA--GIPPPPPL----PGAGIP--PPPPLPRVGIPPPPPLP-GAGI 1162
Query: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG-PGPGPGPG 185
PPP P P V P P G P P P PG G P P P PG
Sbjct: 1163 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP--------PLPGAGIPPPPPLPG 1214
Query: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245
G P PA PLP PGT I PP +
Sbjct: 1215 MGIP--------------------------------PAPAPPLP---PPGTGIPPPPLLP 1239
Query: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPP 274
+ PP P P PPP P
Sbjct: 1240 VSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 53.9 bits (128), Expect = 8e-07
Identities = 92/354 (25%), Positives = 120/354 (33%), Gaps = 65/354 (18%)
Query: 77 APAEGAPGAAPEPPPA---GRAR----PGGGGPQRPGPPSPRRPLVPAGPAPP--AAKLR 127
A AP A P P G R P GG + PG P + L P AA+ R
Sbjct: 229 AEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPR 288
Query: 128 PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPG 187
P + P P V+ P A PA P++ A P P GPG P
Sbjct: 289 EPQQ------PPSPGGLPVSEAPSLPAAQPAAKDSPSSTAF---PFPEAGPGEEAAGAPV 339
Query: 188 KPAGPGAAQTLNGSAALLNSHHAAAP----AVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
+ AG + G +P A + + P L P+ A G
Sbjct: 340 RGAGDTDEE---GEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQG-------- 388
Query: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPP---PPPAPAT---LARPPGHPAGPPTAAPAV 297
P APAA S P +PAP+ P P P T L+ P P+ P +P +
Sbjct: 389 -----PDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRI 443
Query: 298 P--PPAAAQNGGSAGAAPAPAPA------AGGPAGVSGQ-----------PGPGAAAAAP 338
P + G A APA G AG+S P G +A
Sbjct: 444 KRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLL 503
Query: 339 APGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP 392
GV ++S V A AA+ A A ++ G T+ L S PP
Sbjct: 504 ERGVASDSGGGVSPAL--AAKASGAPAAADGFQNVFTGRTLLEKLFSQQENGPP 555
Score = 42.4 bits (98), Expect = 0.002
Identities = 73/281 (25%), Positives = 106/281 (37%), Gaps = 70/281 (24%)
Query: 173 GPGPGPGPGPGPGPGKP--------AGPGAAQ-TLNGSAALLNSHHAAAPAVSLVNNGPA 223
GPG GPGP G+P AG Q T +GS + S H+A L+++
Sbjct: 143 GPG-GPGPAEARVGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQ 201
Query: 224 A-----------------------LLPLPKPAAPGTVIQTPP---------FVGAAAPPA 251
A L +PAAP T + P +G +
Sbjct: 202 AIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAG 261
Query: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG-PPTAAPAVP-PPAAAQNGGSA 309
A SP A +A + P P +PP P G P + AP++P AA++ S+
Sbjct: 262 EAPGSPDTEQALSALSDLPESLAAEPREPQQPPS-PGGLPVSEAPSLPAAQPAAKDSPSS 320
Query: 310 GAAPAP-----APAAGGP---AGVSGQPGP---------GAAAAAPAPGVKAESPKRVVQ 352
A P P AAG P AG + + G G+ AP V ++P+R+ +
Sbjct: 321 TAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGE 380
Query: 353 AAPPAAQTLAASGPASTAASMVIG---PTMQGALPSPAAVP 390
AQ GP + AA+ + G P+ + P P P
Sbjct: 381 EPEEEAQ-----GPDAPAAASLPGSPAPSQRCFKPYPLITP 416
Score = 38.1 bits (87), Expect = 0.045
Identities = 43/143 (30%), Positives = 47/143 (32%), Gaps = 23/143 (16%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPP------PAGRARPGGGGPQRPG------PPSPRR-- 112
P AG P P GA G P PP P PG G P P PP P
Sbjct: 1156 PLPGAGIPPPPPLPGA-GIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1214
Query: 113 ---PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAAR 169
P PA P PP PPP S P+ + P P G P P+ L
Sbjct: 1215 MGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLF-- 1272
Query: 170 AGPGPGPGPGPGPGPGPGKPAGP 192
G G G P +P P
Sbjct: 1273 ---GLGMNQDKGSRKQPIEPCRP 1292
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 127 bits (320), Expect = 4e-29
Identities = 190/788 (24%), Positives = 266/788 (33%), Gaps = 119/788 (15%)
Query: 44 APRTPEVRAAAAGALGNHVVSGSPAGAAGAGPA-APAEGAPGAAPEPPPAGRARPGGGGP 102
AP TP+ A PA PA + AP EP P +P P
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV-PAAAAVAAGPEPAPAGPAKPA 161
+ P P +P+ P P P PA + P + AP P A EPAP P +PA
Sbjct: 315 KEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373
Query: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
P P P P P T + PA + +
Sbjct: 374 ----------------PTTTKEPSPTTPKEPAPTTTKSAPTT------TKEPAPTTTKSA 411
Query: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP------- 274
P PK +P T + P PAP P PA P PA P P
Sbjct: 412 PTT----PKEPSPTTTKEPAP--TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
Query: 275 PAPATLARPPGHPAGPPTAAPAVP----PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330
PAP T P P P AP P P + + PAP +P
Sbjct: 466 PAPTTPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523
Query: 331 PGAAAAAPAPGV-KAESPKRVVQAAPPAAQTLAAS---GPASTAASMVIGPTMQGALPSP 386
P PAP KA +P + AP + A + PA T T +G +P
Sbjct: 524 P-TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT--AP 580
Query: 387 AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNI 446
+ PAP TP K A + + ++ PT+TT A TP AP P+ P T
Sbjct: 581 TTLKEPAPTTP---KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637
Query: 447 QNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMA--------PRPATPTSA 498
+ P + L P + A P TT P P TP
Sbjct: 638 E-----PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692
Query: 499 PPVQISTVQAPGTPIIARQVTPTT---IIKQVSQAQTTVQPSATLQRSPGVQ-PQLVLGG 554
P AP TP TP T +VS TT +P+ T+ +SP P+L
Sbjct: 693 APT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT-TIHKSPDESTPEL---S 747
Query: 555 AAQTASLGTATAVQTGTPQRTVPGAT---TTSSAATETMENVKKCKNFLSTLIKLASSGK 611
A T + + G P P AT T++A +T E ++ +T ++ K
Sbjct: 748 AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE-----RDLRTTPETTTAAPK 802
Query: 612 QSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDS 671
+ ETA ++ ++ KI A T+++ P+ + LK + A
Sbjct: 803 MTKETATTTEKTTES----KITAT--TTQVTSTTTQDTTPFKITTLKTTTLA-------- 848
Query: 672 AAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVG 731
P T+ T T +++ + K AT + A P +PT+
Sbjct: 849 -----------PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP---KPQKPTKAP 894
Query: 732 VGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRI---MLTTPQQIQLNPL 788
P + + KP P ++T T + P +RI ML T + P
Sbjct: 895 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPEL----NPTSRIAEAMLQTTTRPNQTPN 950
Query: 789 QPVPVVKP 796
+ V P
Sbjct: 951 SKLVEVNP 958
Score = 72.8 bits (177), Expect = 2e-12
Identities = 148/725 (20%), Positives = 216/725 (29%), Gaps = 96/725 (13%)
Query: 253 AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA 312
A P+P A PA P P P P P + P P P ++ +
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPT--------PTTPKEPASTTPKEPTPTTIKSAPTTPKE 246
Query: 313 PAPAPAAGGPA-------GVSGQPGP-------GAAAAAPAPGVKAESPKRVVQAAPPAA 358
PAP P + +P P PAP +P + AP
Sbjct: 247 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 306
Query: 359 QTLAASGPASTAASMVIGPT----------------MQGALPSPAAVPPPAPGTP----T 398
+ A + P A + PT P+P A PAP TP
Sbjct: 307 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 366
Query: 399 GLPKGAAGAVTQSLSRT------PTATTSGIRATLTP----TVLAPRLPQPPQNPTNIQN 448
PK A T+ S T PT T S T P T AP P+ P T +
Sbjct: 367 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 426
Query: 449 FQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQA 508
P + P++ + P TT P P TP P A
Sbjct: 427 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PAPTTTKKPAPTTPKEPAPTTPKET-A 483
Query: 509 PGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQ 568
P TP +++TPTT K P+ + +P P+ + + T A
Sbjct: 484 PTTP---KKLTPTTPEKLAPTTPEKPAPTTPEELAP-TTPEEPTPTTPEEPAPTTPKAAA 539
Query: 569 TGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLL 628
TP+ P + T K T K + K+ L
Sbjct: 540 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 599
Query: 629 DGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQ----LTPDSAAFIQQSQQQPPP 684
E ++ + ++P+ K P + TP A + P
Sbjct: 600 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659
Query: 685 PTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQ 744
P A L T+ K A T P T P + +P P +
Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP-----TTPKEPAPTTPKKPAPTTPE 714
Query: 745 QPPKPGALIRPPQVTLTQTPMVALRQPHNRI----MLTTPQQIQLNPLQPVPVVKPAVLP 800
PP + + P T T+ P + P TP+ ++ +P +P +P
Sbjct: 715 TPPPTTSEVSTP--TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP-------GVP 765
Query: 801 GTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELV 860
TK +A + K+K E RD + + A E + T +
Sbjct: 766 TTKTPAATKPEMTTTAKDKTTE------RDLRTTPETTTAAPKMTKETATTTEKTTESKI 819
Query: 861 GTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVSYVSHATQQRLQNLVEKISET 920
T T P + L+ T L P V + T + N K ET
Sbjct: 820 TATTTQVTSTTTQDTTPFKITTLK------TTTLAPKVTTTKKTITTTEIMN---KPEET 870
Query: 921 AQQKN 925
A+ K+
Sbjct: 871 AKPKD 875
Score = 45.4 bits (106), Expect = 3e-04
Identities = 106/488 (21%), Positives = 141/488 (28%), Gaps = 99/488 (20%)
Query: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL----- 400
+P V A P GPA T T + PA+ P P TPT +
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK----EPASTTPKEP-TPTTIKSAPT 242
Query: 401 -PKGAAGAVTQSLSRT---PTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMV 456
PK A T+S T P TT+ A TP AP + P PT ++ P
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKSAPTTP--- 298
Query: 457 LVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIAR 516
P T P P TP P T TP +
Sbjct: 299 -----------------------KEPAPTTPKKPAPTTPKEPAP----TTPKEPTPTTPK 331
Query: 517 QVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQR-T 575
+ PTT + T +P+ T + P P A T T + +P
Sbjct: 332 EPAPTT---KEPAPTTPKEPAPTAPKKPA--PTTPKEPAPTTPKEPAPTTTKEPSPTTPK 386
Query: 576 VPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAE 635
P TTT SA T T E T K S KE
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------------- 433
Query: 636 DFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTA 695
P P TP A + ++P P T + T
Sbjct: 434 -------------PAP---------------TTPKKPA--PTTPKEPAPTTPKEPAPTTT 463
Query: 696 VVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRP 755
+ + + T T+ P L+ T P ++ +P P P+ A P
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----PEELAPTTP 519
Query: 756 PQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAA 815
+ T T A P T + P +P P P T +A + A
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579
Query: 816 QKNKLKEP 823
LKEP
Sbjct: 580 -PTTLKEP 586
Score = 37.0 bits (84), Expect = 0.10
Identities = 83/434 (19%), Positives = 134/434 (30%), Gaps = 42/434 (9%)
Query: 386 PAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTN 445
P PP +GL G T S T S T + PR PP + T+
Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 137
Query: 446 IQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIST 505
+ L + ++ + + QT+ + T ++ I
Sbjct: 138 KET----------------SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 181
Query: 506 VQAPGTPIIARQVTPTT--IIKQVSQAQTTVQ-PSATLQRSPGVQPQLVLGGAAQTASLG 562
A+ + PT+ + K +A+TT + P+ T + P P A+ T
Sbjct: 182 TS-------AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP--TPTTPKEPASTTPKEP 232
Query: 563 TATAVQTGTPQRTVPGATTTSSAATETMENV-KKCKNFLSTLIK--LASSGKQSTETAAN 619
T T +++ P TTT SA T E K T K ++ K+ T
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292
Query: 620 VKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQ 679
+ + ++P+ K P ++ P + +
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 352
Query: 680 QQPPPPTSQATTALT-----AVVLSSSVQRTAGKTAATVTSALQPPVLSLTQP--TQVGV 732
+ P PT+ A T A + T K A T+ P P T+
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412
Query: 733 GKQGQPTPLVIQQP----PKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPL 788
+P+P ++P PK A P + T A P TT + P
Sbjct: 413 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 472
Query: 789 QPVPVVKPAVLPGT 802
+P P P T
Sbjct: 473 EPAPTTPKETAPTT 486
Score = 30.4 bits (67), Expect = 9.5
Identities = 68/343 (19%), Positives = 112/343 (32%), Gaps = 33/343 (9%)
Query: 495 PTSAPPVQISTVQAPGTPIIA---RQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLV 551
PT PPV V G+ + + TP T Q ++ T+ P T + +P L
Sbjct: 78 PTPKPPV----VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSLP 131
Query: 552 LGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGK 611
S T+ V T T TT +T+ E K S A
Sbjct: 132 PNS---DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188
Query: 612 QSTETAANVKELVQNLLDGKI--EAEDFTSRLYRELNSSPQPYLVPFLKRSLPAL-RQLT 668
+++ A + G ++ T +E S+ P +S P ++
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 669 PDSAAFIQQSQQQPPPPTSQATTALT----AVVLSSSVQRTAGKTAATVT---SALQPPV 721
P + + ++P P T++ T A + T K+A T + P
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308
Query: 722 LSLTQPTQVGVGKQGQPTPLVIQQP-----------PKPGALIRPPQVTLTQTPMVALRQ 770
+ T P + +PTP ++P PK A P + T A
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368
Query: 771 PHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAA 813
P TT + P +P P + TK + + ++A
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 127 bits (320), Expect = 4e-29
Identities = 190/788 (24%), Positives = 266/788 (33%), Gaps = 119/788 (15%)
Query: 44 APRTPEVRAAAAGALGNHVVSGSPAGAAGAGPA-APAEGAPGAAPEPPPAGRARPGGGGP 102
AP TP+ A PA PA + AP EP P +P P
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV-PAAAAVAAGPEPAPAGPAKPA 161
+ P P +P+ P P P PA + P + AP P A EPAP P +PA
Sbjct: 356 KEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414
Query: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
P P P P P T + PA + +
Sbjct: 415 ----------------PTTTKEPSPTTPKEPAPTTTKSAPTT------TKEPAPTTTKSA 452
Query: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP------- 274
P PK +P T + P PAP P PA P PA P P
Sbjct: 453 PTT----PKEPSPTTTKEPAP--TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
Query: 275 PAPATLARPPGHPAGPPTAAPAVP----PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330
PAP T P P P AP P P + + PAP +P
Sbjct: 507 PAPTTPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564
Query: 331 PGAAAAAPAPGV-KAESPKRVVQAAPPAAQTLAAS---GPASTAASMVIGPTMQGALPSP 386
P PAP KA +P + AP + A + PA T T +G +P
Sbjct: 565 P-TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT--AP 621
Query: 387 AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNI 446
+ PAP TP K A + + ++ PT+TT A TP AP P+ P T
Sbjct: 622 TTLKEPAPTTP---KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678
Query: 447 QNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMA--------PRPATPTSA 498
+ P + L P + A P TT P P TP
Sbjct: 679 E-----PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733
Query: 499 PPVQISTVQAPGTPIIARQVTPTT---IIKQVSQAQTTVQPSATLQRSPGVQ-PQLVLGG 554
P AP TP TP T +VS TT +P+ T+ +SP P+L
Sbjct: 734 APT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT-TIHKSPDESTPEL---S 788
Query: 555 AAQTASLGTATAVQTGTPQRTVPGAT---TTSSAATETMENVKKCKNFLSTLIKLASSGK 611
A T + + G P P AT T++A +T E ++ +T ++ K
Sbjct: 789 AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE-----RDLRTTPETTTAAPK 843
Query: 612 QSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDS 671
+ ETA ++ ++ KI A T+++ P+ + LK + A
Sbjct: 844 MTKETATTTEKTTES----KITAT--TTQVTSTTTQDTTPFKITTLKTTTLA-------- 889
Query: 672 AAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVG 731
P T+ T T +++ + K AT + A P +PT+
Sbjct: 890 -----------PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP---KPQKPTKAP 935
Query: 732 VGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRI---MLTTPQQIQLNPL 788
P + + KP P ++T T + P +RI ML T + P
Sbjct: 936 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPEL----NPTSRIAEAMLQTTTRPNQTPN 991
Query: 789 QPVPVVKP 796
+ V P
Sbjct: 992 SKLVEVNP 999
Score = 72.8 bits (177), Expect = 2e-12
Identities = 148/725 (20%), Positives = 216/725 (29%), Gaps = 96/725 (13%)
Query: 253 AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA 312
A P+P A PA P P P P P + P P P ++ +
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPT--------PTTPKEPASTTPKEPTPTTIKSAPTTPKE 287
Query: 313 PAPAPAAGGPA-------GVSGQPGP-------GAAAAAPAPGVKAESPKRVVQAAPPAA 358
PAP P + +P P PAP +P + AP
Sbjct: 288 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 347
Query: 359 QTLAASGPASTAASMVIGPT----------------MQGALPSPAAVPPPAPGTP----T 398
+ A + P A + PT P+P A PAP TP
Sbjct: 348 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 407
Query: 399 GLPKGAAGAVTQSLSRT------PTATTSGIRATLTP----TVLAPRLPQPPQNPTNIQN 448
PK A T+ S T PT T S T P T AP P+ P T +
Sbjct: 408 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 467
Query: 449 FQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQA 508
P + P++ + P TT P P TP P A
Sbjct: 468 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PAPTTTKKPAPTTPKEPAPTTPKET-A 524
Query: 509 PGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQ 568
P TP +++TPTT K P+ + +P P+ + + T A
Sbjct: 525 PTTP---KKLTPTTPEKLAPTTPEKPAPTTPEELAP-TTPEEPTPTTPEEPAPTTPKAAA 580
Query: 569 TGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLL 628
TP+ P + T K T K + K+ L
Sbjct: 581 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 640
Query: 629 DGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQ----LTPDSAAFIQQSQQQPPP 684
E ++ + ++P+ K P + TP A + P
Sbjct: 641 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700
Query: 685 PTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQ 744
P A L T+ K A T P T P + +P P +
Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP-----TTPKEPAPTTPKKPAPTTPE 755
Query: 745 QPPKPGALIRPPQVTLTQTPMVALRQPHNRI----MLTTPQQIQLNPLQPVPVVKPAVLP 800
PP + + P T T+ P + P TP+ ++ +P +P +P
Sbjct: 756 TPPPTTSEVSTP--TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP-------GVP 806
Query: 801 GTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELV 860
TK +A + K+K E RD + + A E + T +
Sbjct: 807 TTKTPAATKPEMTTTAKDKTTE------RDLRTTPETTTAAPKMTKETATTTEKTTESKI 860
Query: 861 GTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVSYVSHATQQRLQNLVEKISET 920
T T P + L+ T L P V + T + N K ET
Sbjct: 861 TATTTQVTSTTTQDTTPFKITTLK------TTTLAPKVTTTKKTITTTEIMN---KPEET 911
Query: 921 AQQKN 925
A+ K+
Sbjct: 912 AKPKD 916
Score = 45.4 bits (106), Expect = 3e-04
Identities = 106/488 (21%), Positives = 141/488 (28%), Gaps = 99/488 (20%)
Query: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL----- 400
+P V A P GPA T T + PA+ P P TPT +
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK----EPASTTPKEP-TPTTIKSAPT 283
Query: 401 -PKGAAGAVTQSLSRT---PTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMV 456
PK A T+S T P TT+ A TP AP + P PT ++ P
Sbjct: 284 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKSAPTTP--- 339
Query: 457 LVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIAR 516
P T P P TP P T TP +
Sbjct: 340 -----------------------KEPAPTTPKKPAPTTPKEPAP----TTPKEPTPTTPK 372
Query: 517 QVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQR-T 575
+ PTT + T +P+ T + P P A T T + +P
Sbjct: 373 EPAPTT---KEPAPTTPKEPAPTAPKKPA--PTTPKEPAPTTPKEPAPTTTKEPSPTTPK 427
Query: 576 VPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAE 635
P TTT SA T T E T K S KE
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------------- 474
Query: 636 DFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTA 695
P P TP A + ++P P T + T
Sbjct: 475 -------------PAP---------------TTPKKPA--PTTPKEPAPTTPKEPAPTTT 504
Query: 696 VVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRP 755
+ + + T T+ P L+ T P ++ +P P P+ A P
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----PEELAPTTP 560
Query: 756 PQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAA 815
+ T T A P T + P +P P P T +A + A
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620
Query: 816 QKNKLKEP 823
LKEP
Sbjct: 621 -PTTLKEP 627
Score = 37.0 bits (84), Expect = 0.10
Identities = 83/434 (19%), Positives = 134/434 (30%), Gaps = 42/434 (9%)
Query: 386 PAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTN 445
P PP +GL G T S T S T + PR PP + T+
Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 178
Query: 446 IQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIST 505
+ L + ++ + + QT+ + T ++ I
Sbjct: 179 KET----------------SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 222
Query: 506 VQAPGTPIIARQVTPTT--IIKQVSQAQTTVQ-PSATLQRSPGVQPQLVLGGAAQTASLG 562
A+ + PT+ + K +A+TT + P+ T + P P A+ T
Sbjct: 223 TS-------AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP--TPTTPKEPASTTPKEP 273
Query: 563 TATAVQTGTPQRTVPGATTTSSAATETMENV-KKCKNFLSTLIK--LASSGKQSTETAAN 619
T T +++ P TTT SA T E K T K ++ K+ T
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333
Query: 620 VKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQ 679
+ + ++P+ K P ++ P + +
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 393
Query: 680 QQPPPPTSQATTALT-----AVVLSSSVQRTAGKTAATVTSALQPPVLSLTQP--TQVGV 732
+ P PT+ A T A + T K A T+ P P T+
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453
Query: 733 GKQGQPTPLVIQQP----PKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPL 788
+P+P ++P PK A P + T A P TT + P
Sbjct: 454 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 513
Query: 789 QPVPVVKPAVLPGT 802
+P P P T
Sbjct: 514 EPAPTTPKETAPTT 527
Score = 30.4 bits (67), Expect = 9.5
Identities = 68/343 (19%), Positives = 112/343 (32%), Gaps = 33/343 (9%)
Query: 495 PTSAPPVQISTVQAPGTPIIA---RQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLV 551
PT PPV V G+ + + TP T Q ++ T+ P T + +P L
Sbjct: 119 PTPKPPV----VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSLP 172
Query: 552 LGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGK 611
S T+ V T T TT +T+ E K S A
Sbjct: 173 PNS---DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229
Query: 612 QSTETAANVKELVQNLLDGKI--EAEDFTSRLYRELNSSPQPYLVPFLKRSLPAL-RQLT 668
+++ A + G ++ T +E S+ P +S P ++
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 669 PDSAAFIQQSQQQPPPPTSQATTALT----AVVLSSSVQRTAGKTAATVT---SALQPPV 721
P + + ++P P T++ T A + T K+A T + P
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349
Query: 722 LSLTQPTQVGVGKQGQPTPLVIQQP-----------PKPGALIRPPQVTLTQTPMVALRQ 770
+ T P + +PTP ++P PK A P + T A
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409
Query: 771 PHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAA 813
P TT + P +P P + TK + + ++A
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 127 bits (320), Expect = 4e-29
Identities = 190/788 (24%), Positives = 266/788 (33%), Gaps = 119/788 (15%)
Query: 44 APRTPEVRAAAAGALGNHVVSGSPAGAAGAGPA-APAEGAPGAAPEPPPAGRARPGGGGP 102
AP TP+ A PA PA + AP EP P +P P
Sbjct: 348 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407
Query: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV-PAAAAVAAGPEPAPAGPAKPA 161
+ P P +P+ P P P PA + P + AP P A EPAP P +PA
Sbjct: 408 KEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466
Query: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
P P P P P T + PA + +
Sbjct: 467 ----------------PTTTKEPSPTTPKEPAPTTTKSAPTT------TKEPAPTTTKSA 504
Query: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP------- 274
P PK +P T + P PAP P PA P PA P P
Sbjct: 505 PTT----PKEPSPTTTKEPAP--TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
Query: 275 PAPATLARPPGHPAGPPTAAPAVP----PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330
PAP T P P P AP P P + + PAP +P
Sbjct: 559 PAPTTPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616
Query: 331 PGAAAAAPAPGV-KAESPKRVVQAAPPAAQTLAAS---GPASTAASMVIGPTMQGALPSP 386
P PAP KA +P + AP + A + PA T T +G +P
Sbjct: 617 P-TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT--AP 673
Query: 387 AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNI 446
+ PAP TP K A + + ++ PT+TT A TP AP P+ P T
Sbjct: 674 TTLKEPAPTTP---KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730
Query: 447 QNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMA--------PRPATPTSA 498
+ P + L P + A P TT P P TP
Sbjct: 731 E-----PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785
Query: 499 PPVQISTVQAPGTPIIARQVTPTT---IIKQVSQAQTTVQPSATLQRSPGVQ-PQLVLGG 554
P AP TP TP T +VS TT +P+ T+ +SP P+L
Sbjct: 786 APT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT-TIHKSPDESTPEL---S 840
Query: 555 AAQTASLGTATAVQTGTPQRTVPGAT---TTSSAATETMENVKKCKNFLSTLIKLASSGK 611
A T + + G P P AT T++A +T E ++ +T ++ K
Sbjct: 841 AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE-----RDLRTTPETTTAAPK 895
Query: 612 QSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDS 671
+ ETA ++ ++ KI A T+++ P+ + LK + A
Sbjct: 896 MTKETATTTEKTTES----KITAT--TTQVTSTTTQDTTPFKITTLKTTTLA-------- 941
Query: 672 AAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVG 731
P T+ T T +++ + K AT + A P +PT+
Sbjct: 942 -----------PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP---KPQKPTKAP 987
Query: 732 VGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRI---MLTTPQQIQLNPL 788
P + + KP P ++T T + P +RI ML T + P
Sbjct: 988 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPEL----NPTSRIAEAMLQTTTRPNQTPN 1043
Query: 789 QPVPVVKP 796
+ V P
Sbjct: 1044 SKLVEVNP 1051
Score = 72.8 bits (177), Expect = 2e-12
Identities = 148/725 (20%), Positives = 216/725 (29%), Gaps = 96/725 (13%)
Query: 253 AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA 312
A P+P A PA P P P P P + P P P ++ +
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPT--------PTTPKEPASTTPKEPTPTTIKSAPTTPKE 339
Query: 313 PAPAPAAGGPA-------GVSGQPGP-------GAAAAAPAPGVKAESPKRVVQAAPPAA 358
PAP P + +P P PAP +P + AP
Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399
Query: 359 QTLAASGPASTAASMVIGPT----------------MQGALPSPAAVPPPAPGTP----T 398
+ A + P A + PT P+P A PAP TP
Sbjct: 400 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 459
Query: 399 GLPKGAAGAVTQSLSRT------PTATTSGIRATLTP----TVLAPRLPQPPQNPTNIQN 448
PK A T+ S T PT T S T P T AP P+ P T +
Sbjct: 460 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 519
Query: 449 FQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQA 508
P + P++ + P TT P P TP P A
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PAPTTTKKPAPTTPKEPAPTTPKET-A 576
Query: 509 PGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQ 568
P TP +++TPTT K P+ + +P P+ + + T A
Sbjct: 577 PTTP---KKLTPTTPEKLAPTTPEKPAPTTPEELAP-TTPEEPTPTTPEEPAPTTPKAAA 632
Query: 569 TGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLL 628
TP+ P + T K T K + K+ L
Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 692
Query: 629 DGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQ----LTPDSAAFIQQSQQQPPP 684
E ++ + ++P+ K P + TP A + P
Sbjct: 693 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 752
Query: 685 PTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQ 744
P A L T+ K A T P T P + +P P +
Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP-----TTPKEPAPTTPKKPAPTTPE 807
Query: 745 QPPKPGALIRPPQVTLTQTPMVALRQPHNRI----MLTTPQQIQLNPLQPVPVVKPAVLP 800
PP + + P T T+ P + P TP+ ++ +P +P +P
Sbjct: 808 TPPPTTSEVSTP--TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP-------GVP 858
Query: 801 GTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELV 860
TK +A + K+K E RD + + A E + T +
Sbjct: 859 TTKTPAATKPEMTTTAKDKTTE------RDLRTTPETTTAAPKMTKETATTTEKTTESKI 912
Query: 861 GTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVSYVSHATQQRLQNLVEKISET 920
T T P + L+ T L P V + T + N K ET
Sbjct: 913 TATTTQVTSTTTQDTTPFKITTLK------TTTLAPKVTTTKKTITTTEIMN---KPEET 963
Query: 921 AQQKN 925
A+ K+
Sbjct: 964 AKPKD 968
Score = 45.4 bits (106), Expect = 3e-04
Identities = 106/488 (21%), Positives = 141/488 (28%), Gaps = 99/488 (20%)
Query: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL----- 400
+P V A P GPA T T + PA+ P P TPT +
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK----EPASTTPKEP-TPTTIKSAPT 335
Query: 401 -PKGAAGAVTQSLSRT---PTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMV 456
PK A T+S T P TT+ A TP AP + P PT ++ P
Sbjct: 336 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKSAPTTP--- 391
Query: 457 LVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIAR 516
P T P P TP P T TP +
Sbjct: 392 -----------------------KEPAPTTPKKPAPTTPKEPAP----TTPKEPTPTTPK 424
Query: 517 QVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQR-T 575
+ PTT + T +P+ T + P P A T T + +P
Sbjct: 425 EPAPTT---KEPAPTTPKEPAPTAPKKPA--PTTPKEPAPTTPKEPAPTTTKEPSPTTPK 479
Query: 576 VPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAE 635
P TTT SA T T E T K S KE
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------------- 526
Query: 636 DFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTA 695
P P TP A + ++P P T + T
Sbjct: 527 -------------PAP---------------TTPKKPA--PTTPKEPAPTTPKEPAPTTT 556
Query: 696 VVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRP 755
+ + + T T+ P L+ T P ++ +P P P+ A P
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----PEELAPTTP 612
Query: 756 PQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAA 815
+ T T A P T + P +P P P T +A + A
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 672
Query: 816 QKNKLKEP 823
LKEP
Sbjct: 673 -PTTLKEP 679
Score = 37.0 bits (84), Expect = 0.10
Identities = 83/434 (19%), Positives = 134/434 (30%), Gaps = 42/434 (9%)
Query: 386 PAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTN 445
P PP +GL G T S T S T + PR PP + T+
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 230
Query: 446 IQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIST 505
+ L + ++ + + QT+ + T ++ I
Sbjct: 231 KET----------------SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 274
Query: 506 VQAPGTPIIARQVTPTT--IIKQVSQAQTTVQ-PSATLQRSPGVQPQLVLGGAAQTASLG 562
A+ + PT+ + K +A+TT + P+ T + P P A+ T
Sbjct: 275 TS-------AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP--TPTTPKEPASTTPKEP 325
Query: 563 TATAVQTGTPQRTVPGATTTSSAATETMENV-KKCKNFLSTLIK--LASSGKQSTETAAN 619
T T +++ P TTT SA T E K T K ++ K+ T
Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 620 VKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQ 679
+ + ++P+ K P ++ P + +
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 445
Query: 680 QQPPPPTSQATTALT-----AVVLSSSVQRTAGKTAATVTSALQPPVLSLTQP--TQVGV 732
+ P PT+ A T A + T K A T+ P P T+
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505
Query: 733 GKQGQPTPLVIQQP----PKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPL 788
+P+P ++P PK A P + T A P TT + P
Sbjct: 506 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565
Query: 789 QPVPVVKPAVLPGT 802
+P P P T
Sbjct: 566 EPAPTTPKETAPTT 579
Score = 30.4 bits (67), Expect = 9.5
Identities = 68/343 (19%), Positives = 112/343 (32%), Gaps = 33/343 (9%)
Query: 495 PTSAPPVQISTVQAPGTPIIA---RQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLV 551
PT PPV V G+ + + TP T Q ++ T+ P T + +P L
Sbjct: 171 PTPKPPV----VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSLP 224
Query: 552 LGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGK 611
S T+ V T T TT +T+ E K S A
Sbjct: 225 PNS---DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 281
Query: 612 QSTETAANVKELVQNLLDGKI--EAEDFTSRLYRELNSSPQPYLVPFLKRSLPAL-RQLT 668
+++ A + G ++ T +E S+ P +S P ++
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 669 PDSAAFIQQSQQQPPPPTSQATTALT----AVVLSSSVQRTAGKTAATVT---SALQPPV 721
P + + ++P P T++ T A + T K+A T + P
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 722 LSLTQPTQVGVGKQGQPTPLVIQQP-----------PKPGALIRPPQVTLTQTPMVALRQ 770
+ T P + +PTP ++P PK A P + T A
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461
Query: 771 PHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAA 813
P TT + P +P P + TK + + ++A
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 127 bits (320), Expect = 4e-29
Identities = 190/788 (24%), Positives = 266/788 (33%), Gaps = 119/788 (15%)
Query: 44 APRTPEVRAAAAGALGNHVVSGSPAGAAGAGPA-APAEGAPGAAPEPPPAGRARPGGGGP 102
AP TP+ A PA PA + AP EP P +P P
Sbjct: 389 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448
Query: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV-PAAAAVAAGPEPAPAGPAKPA 161
+ P P +P+ P P P PA + P + AP P A EPAP P +PA
Sbjct: 449 KEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507
Query: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
P P P P P T + PA + +
Sbjct: 508 ----------------PTTTKEPSPTTPKEPAPTTTKSAPTT------TKEPAPTTTKSA 545
Query: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP------- 274
P PK +P T + P PAP P PA P PA P P
Sbjct: 546 PTT----PKEPSPTTTKEPAP--TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Query: 275 PAPATLARPPGHPAGPPTAAPAVP----PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330
PAP T P P P AP P P + + PAP +P
Sbjct: 600 PAPTTPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657
Query: 331 PGAAAAAPAPGV-KAESPKRVVQAAPPAAQTLAAS---GPASTAASMVIGPTMQGALPSP 386
P PAP KA +P + AP + A + PA T T +G +P
Sbjct: 658 P-TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT--AP 714
Query: 387 AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNI 446
+ PAP TP K A + + ++ PT+TT A TP AP P+ P T
Sbjct: 715 TTLKEPAPTTP---KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771
Query: 447 QNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMA--------PRPATPTSA 498
+ P + L P + A P TT P P TP
Sbjct: 772 E-----PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826
Query: 499 PPVQISTVQAPGTPIIARQVTPTT---IIKQVSQAQTTVQPSATLQRSPGVQ-PQLVLGG 554
P AP TP TP T +VS TT +P+ T+ +SP P+L
Sbjct: 827 APT-TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT-TIHKSPDESTPEL---S 881
Query: 555 AAQTASLGTATAVQTGTPQRTVPGAT---TTSSAATETMENVKKCKNFLSTLIKLASSGK 611
A T + + G P P AT T++A +T E ++ +T ++ K
Sbjct: 882 AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE-----RDLRTTPETTTAAPK 936
Query: 612 QSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDS 671
+ ETA ++ ++ KI A T+++ P+ + LK + A
Sbjct: 937 MTKETATTTEKTTES----KITAT--TTQVTSTTTQDTTPFKITTLKTTTLA-------- 982
Query: 672 AAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVG 731
P T+ T T +++ + K AT + A P +PT+
Sbjct: 983 -----------PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP---KPQKPTKAP 1028
Query: 732 VGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRI---MLTTPQQIQLNPL 788
P + + KP P ++T T + P +RI ML T + P
Sbjct: 1029 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPEL----NPTSRIAEAMLQTTTRPNQTPN 1084
Query: 789 QPVPVVKP 796
+ V P
Sbjct: 1085 SKLVEVNP 1092
Score = 72.8 bits (177), Expect = 2e-12
Identities = 148/725 (20%), Positives = 216/725 (29%), Gaps = 96/725 (13%)
Query: 253 AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA 312
A P+P A PA P P P P P + P P P ++ +
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPT--------PTTPKEPASTTPKEPTPTTIKSAPTTPKE 380
Query: 313 PAPAPAAGGPA-------GVSGQPGP-------GAAAAAPAPGVKAESPKRVVQAAPPAA 358
PAP P + +P P PAP +P + AP
Sbjct: 381 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440
Query: 359 QTLAASGPASTAASMVIGPT----------------MQGALPSPAAVPPPAPGTP----T 398
+ A + P A + PT P+P A PAP TP
Sbjct: 441 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 500
Query: 399 GLPKGAAGAVTQSLSRT------PTATTSGIRATLTP----TVLAPRLPQPPQNPTNIQN 448
PK A T+ S T PT T S T P T AP P+ P T +
Sbjct: 501 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 560
Query: 449 FQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQA 508
P + P++ + P TT P P TP P A
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PAPTTTKKPAPTTPKEPAPTTPKET-A 617
Query: 509 PGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQ 568
P TP +++TPTT K P+ + +P P+ + + T A
Sbjct: 618 PTTP---KKLTPTTPEKLAPTTPEKPAPTTPEELAP-TTPEEPTPTTPEEPAPTTPKAAA 673
Query: 569 TGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLL 628
TP+ P + T K T K + K+ L
Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 733
Query: 629 DGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQ----LTPDSAAFIQQSQQQPPP 684
E ++ + ++P+ K P + TP A + P
Sbjct: 734 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 793
Query: 685 PTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQ 744
P A L T+ K A T P T P + +P P +
Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP-----TTPKEPAPTTPKKPAPTTPE 848
Query: 745 QPPKPGALIRPPQVTLTQTPMVALRQPHNRI----MLTTPQQIQLNPLQPVPVVKPAVLP 800
PP + + P T T+ P + P TP+ ++ +P +P +P
Sbjct: 849 TPPPTTSEVSTP--TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP-------GVP 899
Query: 801 GTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELV 860
TK +A + K+K E RD + + A E + T +
Sbjct: 900 TTKTPAATKPEMTTTAKDKTTE------RDLRTTPETTTAAPKMTKETATTTEKTTESKI 953
Query: 861 GTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVSYVSHATQQRLQNLVEKISET 920
T T P + L+ T L P V + T + N K ET
Sbjct: 954 TATTTQVTSTTTQDTTPFKITTLK------TTTLAPKVTTTKKTITTTEIMN---KPEET 1004
Query: 921 AQQKN 925
A+ K+
Sbjct: 1005 AKPKD 1009
Score = 45.4 bits (106), Expect = 3e-04
Identities = 106/488 (21%), Positives = 141/488 (28%), Gaps = 99/488 (20%)
Query: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL----- 400
+P V A P GPA T T + PA+ P P TPT +
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK----EPASTTPKEP-TPTTIKSAPT 376
Query: 401 -PKGAAGAVTQSLSRT---PTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMV 456
PK A T+S T P TT+ A TP AP + P PT ++ P
Sbjct: 377 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKSAPTTP--- 432
Query: 457 LVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIAR 516
P T P P TP P T TP +
Sbjct: 433 -----------------------KEPAPTTPKKPAPTTPKEPAP----TTPKEPTPTTPK 465
Query: 517 QVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQR-T 575
+ PTT + T +P+ T + P P A T T + +P
Sbjct: 466 EPAPTT---KEPAPTTPKEPAPTAPKKPA--PTTPKEPAPTTPKEPAPTTTKEPSPTTPK 520
Query: 576 VPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAE 635
P TTT SA T T E T K S KE
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------------- 567
Query: 636 DFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTA 695
P P TP A + ++P P T + T
Sbjct: 568 -------------PAP---------------TTPKKPA--PTTPKEPAPTTPKEPAPTTT 597
Query: 696 VVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRP 755
+ + + T T+ P L+ T P ++ +P P P+ A P
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT----PEELAPTTP 653
Query: 756 PQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAA 815
+ T T A P T + P +P P P T +A + A
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713
Query: 816 QKNKLKEP 823
LKEP
Sbjct: 714 -PTTLKEP 720
Score = 37.0 bits (84), Expect = 0.10
Identities = 83/434 (19%), Positives = 134/434 (30%), Gaps = 42/434 (9%)
Query: 386 PAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTN 445
P PP +GL G T S T S T + PR PP + T+
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 271
Query: 446 IQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIST 505
+ L + ++ + + QT+ + T ++ I
Sbjct: 272 KET----------------SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 315
Query: 506 VQAPGTPIIARQVTPTT--IIKQVSQAQTTVQ-PSATLQRSPGVQPQLVLGGAAQTASLG 562
A+ + PT+ + K +A+TT + P+ T + P P A+ T
Sbjct: 316 TS-------AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP--TPTTPKEPASTTPKEP 366
Query: 563 TATAVQTGTPQRTVPGATTTSSAATETMENV-KKCKNFLSTLIK--LASSGKQSTETAAN 619
T T +++ P TTT SA T E K T K ++ K+ T
Sbjct: 367 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 620 VKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQ 679
+ + ++P+ K P ++ P + +
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 486
Query: 680 QQPPPPTSQATTALT-----AVVLSSSVQRTAGKTAATVTSALQPPVLSLTQP--TQVGV 732
+ P PT+ A T A + T K A T+ P P T+
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546
Query: 733 GKQGQPTPLVIQQP----PKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPL 788
+P+P ++P PK A P + T A P TT + P
Sbjct: 547 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606
Query: 789 QPVPVVKPAVLPGT 802
+P P P T
Sbjct: 607 EPAPTTPKETAPTT 620
Score = 30.4 bits (67), Expect = 9.5
Identities = 68/343 (19%), Positives = 112/343 (32%), Gaps = 33/343 (9%)
Query: 495 PTSAPPVQISTVQAPGTPIIA---RQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLV 551
PT PPV V G+ + + TP T Q ++ T+ P T + +P L
Sbjct: 212 PTPKPPV----VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSLP 265
Query: 552 LGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGK 611
S T+ V T T TT +T+ E K S A
Sbjct: 266 PNS---DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 322
Query: 612 QSTETAANVKELVQNLLDGKI--EAEDFTSRLYRELNSSPQPYLVPFLKRSLPAL-RQLT 668
+++ A + G ++ T +E S+ P +S P ++
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 669 PDSAAFIQQSQQQPPPPTSQATTALT----AVVLSSSVQRTAGKTAATVT---SALQPPV 721
P + + ++P P T++ T A + T K+A T + P
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 722 LSLTQPTQVGVGKQGQPTPLVIQQP-----------PKPGALIRPPQVTLTQTPMVALRQ 770
+ T P + +PTP ++P PK A P + T A
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502
Query: 771 PHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAA 813
P TT + P +P P + TK + + ++A
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 114 bits (284), Expect = 7e-25
Identities = 120/372 (32%), Positives = 146/372 (39%), Gaps = 36/372 (9%)
Query: 75 PAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPP--PEG 132
P +P P AP PPA P PPS P + P+PPA+ PP P
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS---PPMSPSA 720
Query: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG--PGPGPGPGPGPGPGKPA 190
+ AP P AA P PA P P P+A P P P P P
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPASP--PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM 778
Query: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNG-----PAALLPLPKPAAPGTVIQTPPFVG 245
P A AL A P+ G P+A LP+ A P Q PP +
Sbjct: 779 SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP--QAPPVL- 835
Query: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA-----TLARPPGHPAGPPTAAPAVPPP 300
AAP PSPPA+P AP P P P TLA PG P PP+ +P+
Sbjct: 836 -AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG-PPPPPSRSPSSTLS 893
Query: 301 AAAQNGGSAGAAPAPAPAAG---GP-AGVSGQPGPGA--AAAAPAPGVKAESPKRVVQAA 354
G S+ A P G GP G + P P A AA PA + +P + A
Sbjct: 894 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 953
Query: 355 PPAAQTL-AASGPASTAASMVIGPT--MQGALPSPAAVPP-PAPGTPTGLPKGAAGAVTQ 410
P A A+GP S I T + A P+P A+ P P+PGT G K AAGA
Sbjct: 954 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAGAG 1011
Query: 411 SLSRTPTATTSG 422
+ SR+P G
Sbjct: 1012 ASSRSPKQARLG 1023
Score = 113 bits (283), Expect = 9e-25
Identities = 132/483 (27%), Positives = 174/483 (36%), Gaps = 80/483 (16%)
Query: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARP---------------------GGGGPQR 104
SP+ A P +P AP + P PP + PQ
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502
Query: 105 P------GPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPA 158
P P + L P P A L PP + S AP P A A P P
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP 562
Query: 159 KPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLV 218
PA P L A P P P P P A A+P + +
Sbjct: 563 CPA-PCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL---------------ASPPLQGL 606
Query: 219 NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAA-------APP 271
+ P + L P P AP + PP +PPA SP A P+P AP A AP
Sbjct: 607 PSPPLSPLATPPPQAP-PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665
Query: 272 PPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP 331
PPP+P A P PA PP + A PP A + + P+P A P S P P
Sbjct: 666 SPPPSPPVQA-PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
Query: 332 GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG-PASTAASMVIGPTMQGALPSPAAVP 390
A AP ++ V +PPA+ ++ S P ++ P +Q PA++P
Sbjct: 725 QAPPPLAAPPLQ-------VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P P A Q+L +P A+ G +A +P+ P P P
Sbjct: 778 MSPLAKPPPQAPPALATPPLQALP-SPPASFPG-QAPFSPSASLPMSPLATPPP------ 829
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAP 509
Q PP + LL +P A QA +P T P P T S P +++ AP
Sbjct: 830 QAPPVLA------APLLQVPPSPPASPTLQAPRRPPT---PGPDTSVSGP--RLTLALAP 878
Query: 510 GTP 512
G P
Sbjct: 879 GPP 881
Score = 113 bits (282), Expect = 1e-24
Identities = 190/770 (24%), Positives = 253/770 (32%), Gaps = 158/770 (20%)
Query: 82 APGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVP 141
A A PA RA PG P+ PG P P P+ PA LR G+AG+ P
Sbjct: 8 AKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVTPAA-------LRVL--GAAGAVGRKP 57
Query: 142 AAAAV-----AAGPEPAP-AGPAKPAG-----PAALAARAGPGPGPGPGPGPGPGPGKPA 190
A A PE AP AGP + AG PA+ +G G P PGP
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117
Query: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250
G + T G L A V G A P + G T + P
Sbjct: 118 GRASGTTRPGP---LGQKGLRISAEETVARGKATEAPKRSALSAGARRDT-------SGP 167
Query: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV-------PPPAAA 303
P PSP A A P PAP+ RPP GP + + P PAA
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE--GPRKSVSSASEHSTTEPSPAAR 225
Query: 304 QNGGSAGAAPAPAP----AAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQ 359
+ + G PA ++ P + GP A AP ++ + +QA P
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 360 TLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTAT 419
T P A+ +GP L +P+ P P P AA + +L +P
Sbjct: 286 T-----PPRKDAAPALGPLSSSPLATPS--PSGTKARPVPPPDNAATPLPATLPPSPPLA 338
Query: 420 TSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQ 479
T P P P P ++Q PP P QA
Sbjct: 339 TP-----------LPLAPPSPSAPPSLQTLPSPPATP------------PSQA------- 368
Query: 480 AHAQPQTTMAPRPATPT--SAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPS 537
P T P A P+ + PP+Q+ + PS
Sbjct: 369 ---PPSMTTPPMQAPPSLQTIPPIQVP--------------------------HSLTSPS 399
Query: 538 ATLQRSPGVQPQLVLGGAAQTASLGTAT-----AVQTGTPQRTVPGATTTSSAATETMEN 592
SP L L T SLG+ T + T +P++T T+ S A+ ++
Sbjct: 400 LQAPPSP-----LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454
Query: 593 VKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPY 652
L + L +S T + V L L ++A L + SPQ
Sbjct: 455 PP-----LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA------LSSLASHSPQAP 503
Query: 653 LVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAAT 712
L + L L P S PP S T L ++ A T
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQ---------TPPASLTTPPL------ENLPSLAPPPLQT 548
Query: 713 VTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIRPP---QVTLTQTPMVALR 769
++ L P L T P Q P+PL P P ++ PP L P+ L
Sbjct: 549 ASAPLTTPHLE-TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607
Query: 770 QPHNRIMLTTPQQ----IQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAA 815
P + T P Q + L PLQ P P P L+ S QA A
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPP--SPPASPPLSPLATPSPQAPNA 655
Score = 103 bits (257), Expect = 9e-22
Identities = 205/841 (24%), Positives = 287/841 (34%), Gaps = 145/841 (17%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP 107
P V AA LG AGA G P A G G A P A RA P
Sbjct: 37 PPVTPAALRVLG-------AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 108 PSPRRPLVPAGPAPPAAK----------------LRPPPEG------------SAGSCAP 139
P+ R P G P AK RP P G + G
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 140 VPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPG-PGPGPGPGKPAGPGAAQTL 198
P +A++AG +GP P P+ AR G G P P P +P P
Sbjct: 150 APKRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRK 207
Query: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA-----PGTVIQTPPFVGAAAPPAPA 253
+ S+A S H+ P+A L +PA+ T + +P G +A P
Sbjct: 208 SVSSA---SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 254 APSPPAAPAPAA------PAAAPPPPPPAPA---TLARPPGHPAGPPTAAPAVPPPAAAQ 304
AP+ P+ P P P PP APA + P P+ T A VPPP A
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAA 324
Query: 305 NGGSAGAAPAP---------APAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAP 355
A P+P P+ P + P P A + AP P + AP
Sbjct: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ----AP 380
Query: 356 PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP--KGAAGAVTQSLS 413
P+ QT+ P + P++Q A PSP A+ T G P + +T S
Sbjct: 381 PSLQTI----PPIQVPHSLTSPSLQ-APPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
Query: 414 RTPTATTSGIRATLTPTVLAP-----RLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMI 468
+T + TS R TP P LP P T++ V + L +
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS--------PAVSPLSSPLTIH 487
Query: 469 PQQALAQMQAQAHAQPQTT--MAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQ 526
P QAL+ + + + P ++ M P + APP ++Q P A TP
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP----SLQTPP----ASLTTP-----P 534
Query: 527 VSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAA 586
+ + P +P P L +T +Q T P T SS A
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHL------ETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588
Query: 587 TETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELN 646
T + LAS Q + + L +A + L
Sbjct: 589 TPPPQAPP----------ALASPPLQGLPSPP-----LSPLATPPPQAPPXLA--LPPLQ 631
Query: 647 SSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPP-PTSQATTALTAVVLSSSVQRT 705
+ P P P L Q A + Q+ PPP P QA + A S V +
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA---SPPVSPS 688
Query: 706 AGKTAATVTSALQPPV-LSLTQPTQVGVGKQGQPTPLV--------IQQPPKPGALIRPP 756
A + S PP+ + + P + P P +Q PP P A P
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA-SPPM 747
Query: 757 QVTLTQTPMV--ALRQPHNRIMLTTPQQIQLNPL-QPVPVVKPAVLPGTKALSAVSAQAA 813
+ T P V L P ++ + P + ++PL +P P PA+ T L A+ + A
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL--ATPPLQALPSPPA 805
Query: 814 A 814
+
Sbjct: 806 S 806
Score = 101 bits (251), Expect = 4e-21
Identities = 148/586 (25%), Positives = 211/586 (36%), Gaps = 87/586 (14%)
Query: 45 PRTPEVRAAAAGALG----NHVVSGSPAGAAGAGPAAPAEGA----PGAAPEPPPAGRAR 96
P+ R AA ALG + + + SP+G A P P + A P P PP
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTK-ARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 97 PGGGGPQRPGPPS----PRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP 152
P P PPS P P P APP+ + PP + S +P + P
Sbjct: 342 PLAP-PSPSAPPSLQTLPSPPATPPSQAPPS--MTTPPMQAPPSLQTIPPIQVPHSLTSP 398
Query: 153 APAGPAKPAGPAALAARAGPGP------------GPGPGPGPGPGPGKPAG-PGAAQTLN 199
+ P P ++L A G P P +PA P + L
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
Query: 200 GSAALLNS---HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS 256
+L S + +PAVS +++ P + PL ++ + P PP S
Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSS-PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS 517
Query: 257 --PPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA 314
PP+ P PA+ PP +LA PP A P P + P PA
Sbjct: 518 LAPPSLQTP--PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP----------PCPA 565
Query: 315 PAPAAGGPAGVSGQP--GPGAAAAAP--APGVKAESPKRVVQAAPPAAQTLAASGPASTA 370
P P P+ ++ P P + A P AP A P +Q P + A+ P
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP---LQGLPSPPLSPLATPPPQAP 622
Query: 371 ASMVIGPTMQGALPSPAAVPPPAP-GTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTP 429
+ + P A PSP A PP +P TP+ A A+ L + P + +P
Sbjct: 623 PXLALPPLQ--APPSPPASPPLSPLATPS---PQAPNALAVHLLQAPFSPPP------SP 671
Query: 430 TVLAPRLP--QPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTT 487
V AP P PP +P+ Q PP L P Q A P T
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPP----------SLAAPPLQVPPSPPASPPMSPSAT 721
Query: 488 MAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQA---QTTVQPSATLQRSP 544
P+ P +APP+Q+ P +P ++ TP + + A Q P A+L SP
Sbjct: 722 PPPQAPPPLAAPPLQVPP-SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Query: 545 GVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETM 590
+P +L T +P + PG S +A+ M
Sbjct: 781 LAKPP-----PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821
Score = 76.6 bits (187), Expect = 1e-13
Identities = 89/320 (27%), Positives = 111/320 (34%), Gaps = 41/320 (12%)
Query: 83 PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS------ 136
P P PPA P PP+ P + A P+PPA+ P + S
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Query: 137 CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPG-PGP------GPGPGKP 189
P P A V A P P+ PA P A R P PGP GP PGP P
Sbjct: 825 ATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 883
Query: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSL--VNNGPAALLPLPKPAAPGTVIQTPPFVGAA 247
+ TL+G +S A + L ++GP G +PP
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE-----------GGAAASPPPDAEL 932
Query: 248 APPAPAA----PSPPAA--PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301
A PAA P+PP A AP AP PP P A GP +A PA P
Sbjct: 933 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA---PG 989
Query: 302 AAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ-----AAPP 356
A G S G + A A G S P P ++A + ++ AA
Sbjct: 990 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 1049
Query: 357 AAQTLAASGPASTAASMVIG 376
A + GP V G
Sbjct: 1050 GAAGGSGGGPGGAEGGGVTG 1069
Score = 67.4 bits (163), Expect = 7e-11
Identities = 81/286 (28%), Positives = 96/286 (33%), Gaps = 38/286 (13%)
Query: 77 APAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA-----AKLRPPPE 131
+P PG AP P A P PP PL+ P+PPA A RPP
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
Query: 132 GSAGSCAPVPAAAAVAAGPEPAPA-GPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190
G S + A+A GP P P+ P+ LA + P G +
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST-----PEELRGYDS 916
Query: 191 GP--GAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAA 248
GP GAA + A L H AA + GPA PL APG + PP G +
Sbjct: 917 GPEGGAAASPPPDAELAACHPAAW------SRGPAP--PLAFRGAPGAPLPWPPATGPGS 968
Query: 249 PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG-------PPTAAPAVPPPA 301
P A PA P P+P T AG P A P
Sbjct: 969 ADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG 1028
Query: 302 AAQNGGS----------AGAAPAPAPAAGGPAGVSGQPGPGAAAAA 337
A Q A A A + GGP G G G A AA
Sbjct: 1029 ALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAA 1074
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/184 (32%), Positives = 64/184 (34%), Gaps = 33/184 (17%)
Query: 38 AHHHHLAPRTPE-VRAAAAGALGNHVVSGSPAGAAGA--------GPAAPA--EGAPGAA 86
A H A TPE +R +G G S P A GPA P GAPGA
Sbjct: 898 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957
Query: 87 -PEPPPAGRARPGGGGP--QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAA 143
P PP G G + GP S A PAP A P P S G A A
Sbjct: 958 LPWPPATGPGSADGLCTIYETEGPES-------ATPAPGALDPGPSPGTSGGKAAAGAGA 1010
Query: 144 AAVAAGPEPAPAGPAKPAGPAA------------LAARAGPGPGPGPGPGPGPGPGKPAG 191
A + P+ A G A LAA G G G GPG G G G
Sbjct: 1011 GASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 1070
Query: 192 PGAA 195
AA
Sbjct: 1071 ARAA 1074
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 112 bits (280), Expect = 2e-24
Identities = 126/451 (27%), Positives = 151/451 (33%), Gaps = 85/451 (18%)
Query: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARP------GGGGPQRPGP-------PSPRR 112
SP+ AG AP +G G P+ PP+ +P GG PQ P P P P+
Sbjct: 28 SPSLIAGNPQGAPPQG--GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 113 PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAAR-AG 171
P GP PP PPP+G P P P G +P GP + G
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG----PPPQGGNQPQGPPPPPGKPQG 141
Query: 172 PGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP 231
P P G P P PGKP GP Q N S + + P P P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGP-PPQGDNKSRS---------------SRSPPGKPQGPPP 185
Query: 232 AAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLAR-PPGHPAGP 290
PP G P P + P P P PPP + AR PPG P GP
Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245
Query: 291 PTAA---PAVPPPAAAQNGG---SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344
P P PPP + G G P P G P G Q G + ++ PG K
Sbjct: 246 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG-KP 304
Query: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA 404
+ P PP P GP QG PP PG P G P
Sbjct: 305 QGP-------PPQGGNQPQGPPPPPGKPQ--GPPPQGGNKPQG---PPPPGKPQG-PPPQ 351
Query: 405 AGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQ 464
G+ ++S +R+P G PPQ N PP G
Sbjct: 352 GGSKSRS-ARSPPGKPQG----------------PPQQEGNNPQGPPPPA-------GGN 387
Query: 465 LLMIPQQALAQMQAQAHAQPQTTMAPRPATP 495
PQQ A Q P+ RP+ P
Sbjct: 388 ----PQQPQAPPAGQPQGPPRPPQGGRPSRP 414
Score = 112 bits (280), Expect = 2e-24
Identities = 116/406 (28%), Positives = 137/406 (33%), Gaps = 89/406 (21%)
Query: 62 VVSGSPAGAAGAGPAAPA--EGAPGAAPEPPPAGRARPGGGGPQ--RPGPPSPRRPLVPA 117
+++G+P GA G P PG PPP G +P G P +P P P+ P
Sbjct: 31 LIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 90
Query: 118 GPAPPAAKLRPPPEGSAGSC---------APVPAAAAVAAGPEPAPAGP----------- 157
GP PP PPP+G P P GP P P P
Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 150
Query: 158 ------AKPAGPA------ALAARAGPGPGPGPGP-------GPGPGPGKPAGPGAAQTL 198
KP GP + ++R+ PG GP P GP P PGKP GP Q
Sbjct: 151 QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-PPQGG 209
Query: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG---AAAPPAPAAP 255
N P N +A P KP P PP G PP P P
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP------PPQGGNQPQGPPPPPGKP 263
Query: 256 SPPAAPAPAAPAAAPPP-----PPPAPATLAR----PPGHPAGPPTAA---PAVPPPAAA 303
P P PPP PPP + +R PPG P GPP P PPP
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323
Query: 304 QNGG---SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQT 360
+ G G P P G P G Q G + +A PG P+ PP +
Sbjct: 324 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPG----KPQ-----GPPQQEG 374
Query: 361 LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAG 406
GP P G P PP G P G P+ G
Sbjct: 375 NNPQGP----------PPPAGGNPQQPQAPP--AGQPQGPPRPPQG 408
Score = 102 bits (253), Expect = 3e-21
Identities = 97/321 (30%), Positives = 114/321 (35%), Gaps = 59/321 (18%)
Query: 64 SGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRAR--PGGGGPQRPGPPSPRRPLVP----- 116
S SP G P +G PPP G+ + P GG + GPP P +P P
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 167
Query: 117 ----AGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP-------APAGPAKPAGPA- 164
+ +PP PPP+G P P GP P P P KP GP
Sbjct: 168 NKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGGNKPQGPPPPGKPQGPPP 226
Query: 165 -----ALAARAGPGPGPGPGP-------GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAA 212
+ +AR+ PG GP P GP P PGKP GP Q N
Sbjct: 227 QGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-PPQGGNKPQGPPPPGKPQG 285
Query: 213 PAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAA---PAAA 269
P + ++ P KP P PP G P P P P P P
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGP------PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 339
Query: 270 PPP-----PPPAPATLAR----PPGHPAGPPTAA---PAVPPPAAAQNGGSAGAAPAPAP 317
PPP PPP + +R PPG P GPP P PPP A N AP
Sbjct: 340 PPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGN-----PQQPQAP 394
Query: 318 AAGGPAGVSGQPGPGAAAAAP 338
AG P G P G + P
Sbjct: 395 PAGQPQGPPRPPQGGRPSRPP 415
Score = 64.7 bits (156), Expect = 5e-10
Identities = 79/318 (24%), Positives = 94/318 (29%), Gaps = 58/318 (18%)
Query: 201 SAALLNSHHAAAPAVSLVNNGPAAL------LPLPKPAAPGTVIQTPPFVGAAAPPAPAA 254
SA LN + + SL+ P P P+ PG PP G P
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPP 74
Query: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA 314
P P P P PPPP P G + P + P P Q G P
Sbjct: 75 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP 134
Query: 315 PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMV 374
P GP P G P P K + P PP + S +
Sbjct: 135 PPGKPQGP-----PPQGGNKPQGPPPPGKPQGP-------PPQGDNKSRSSRSPPGKPQ- 181
Query: 375 IGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAP 434
GP QG + PPP PG P G P G + P P
Sbjct: 182 -GPPPQGG--NQPQGPPPPPGKPQGPP-----------------PQGGNKPQGPPPPGKP 221
Query: 435 RLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPAT 494
+ P PPQ Q+ + PPG PQ Q Q P P P
Sbjct: 222 QGP-PPQGDNKSQSARSPPGK-------------PQGPPPQGGNQPQGPP-----PPPGK 262
Query: 495 PTSAPPVQISTVQAPGTP 512
P PP + Q P P
Sbjct: 263 PQGPPPQGGNKPQGPPPP 280
Score = 38.1 bits (87), Expect = 0.045
Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 4/93 (4%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPP--PAGRARPGGGGP 102
P P + G + G P GP +A PP P G + G P
Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNP 377
Query: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG 135
Q P PP+ P P APPA + + PP G
Sbjct: 378 QGPPPPAGGNPQQPQ--APPAGQPQGPPRPPQG 408
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 111 bits (278), Expect = 3e-24
Identities = 127/404 (31%), Positives = 146/404 (36%), Gaps = 74/404 (18%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPA--EGAPGAAPEPPPAGRARPGG--G 100
P+ A G+ G+ G P GP PA EG GA EP P G P G G
Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488
Query: 101 GPQRPGPPSPRRPLVPAGPAPPAAKLRPP-PEGSAGSC-----APVPAAAAVAAGP-EPA 153
GP G P P GPA P P+GS G A +P A + P P
Sbjct: 489 GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548
Query: 154 PAGPAKPAGPAALAARAGPGPGPG----------PGP-GPGPGPGK------PAGPGAAQ 196
P G P GPA R GP PG PGP G PGK P PGA
Sbjct: 549 PDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVG 608
Query: 197 TL--NGSAALLNSHHAAAPAVSLVNNGPA---ALLPLPKPAAPGTVIQTPPFVGAAAPPA 251
+G A A PA GPA LP PA P A P
Sbjct: 609 PAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG--------EAGKPGE 660
Query: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGA 311
P AP P+ A P + PPG PAGP A A N G+ G
Sbjct: 661 QGVPGDLGAPGPS--GARGERGFPGERGVQGPPG-PAGPRGA------NGAPGNDGAKGD 711
Query: 312 APAP-APAAGGPAGVSGQPGPGAAAAAPAP-GVKAESPKRVVQAAPPAAQTLAASGPAST 369
A AP AP + G G+ G PG AA P P G + ++ + +P +GP
Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP--- 768
Query: 370 AASMVIGPTMQGALPSPAAVP-------PPAPGTPTGLPKGAAG 406
IGP P PA P P P PTG +GA G
Sbjct: 769 -----IGP------PGPAGAPGDKGESGPSGPAGPTG-ARGAPG 800
Score = 110 bits (275), Expect = 7e-24
Identities = 171/572 (29%), Positives = 190/572 (33%), Gaps = 146/572 (25%)
Query: 55 AGALGNHVVSGS-----PAGAAG-------------AGPAAP--AEGAPGAAPEPPPAGR 94
AGA GN +G+ P G AG AGP P +EG G EP P G
Sbjct: 319 AGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378
Query: 95 A-------------RPGGGGPQ-------RPGPPSPRRPLVPAGPAPPAAKLRPPPEGSA 134
A +PG G PG P R P P GP P P P+G++
Sbjct: 379 AGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGP-----PGPKGNS 433
Query: 135 GSCAPVPAAAAVAAGPEPAPAGPAKPAGPAA----LAARAGPGPGPGPGP-----GPG-- 183
G + A EP P G P GPA AR PGP PGP GPG
Sbjct: 434 GEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSR 493
Query: 184 --------------------PGPGKPAG-PGAA-----QTLNGSAALLNSHHAAAPAVSL 217
PGP P G PG A L G+ L S + P
Sbjct: 494 GFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT 553
Query: 218 VNNGPAALLPLPKPAAP------GTVIQTPPFVGAAAPPAPA----APSPPAAPAPA--- 264
GPA P P P V+ P GAA P A P PP A PA
Sbjct: 554 GPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD 613
Query: 265 APAAAPPPPPPAPATLARPPGHPAGPP----TAAPAVPPPAAAQNG--GSAG--AAPAPA 316
A A PP PA R PAG P PA PP A + G G G AP P+
Sbjct: 614 GEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPS 673
Query: 317 PAAG-----GPAGVSGQPGP-------------GAAAAAPAPGVKAESPKRVVQAAPPAA 358
A G G GV G PGP GA A APG +Q P
Sbjct: 674 GARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGER 733
Query: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTA 418
GP GP +GA SP P G P G AGA P+
Sbjct: 734 GAAGLPGPKGDRGD--AGP--KGADGSPGKDGVRGLTGPIG-PPGPAGAPGDKGESGPSG 788
Query: 419 TTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQA 478
A P R P P F PPG G+ P A A
Sbjct: 789 PAGPTGARGAP---GDRGEPGPPGPA---GFAGPPGADGQPGAKGE----PGDA----GA 834
Query: 479 QAHAQPQTTMAPRPATPTSAPPVQISTVQAPG 510
+ A P P PA P + PP I V APG
Sbjct: 835 KGDAGP-----PGPAGP-AGPPGPIGNVGAPG 860
Score = 110 bits (275), Expect = 7e-24
Identities = 134/436 (30%), Positives = 146/436 (33%), Gaps = 92/436 (21%)
Query: 52 AAAAGALGNHVVSGSPAGAAGAGPAAPA--EGAPGAAPEPPPAGRARPGGGGPQRPGPPS 109
A GA G GSP GP PA +G PG P PP R + G G PGP
Sbjct: 532 AGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPG--PPGPPGARGQAGVMG--FPGPKG 587
Query: 110 PRRPLVPAG----PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGP------AK 159
AG P PP A +G AG+ P A E PAG
Sbjct: 588 AAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG 647
Query: 160 PAGPAALAARAGPGPGPGPGPGPGP----------------GPGKPAGPGAAQTLNGSAA 203
PAGP A + G PG PGP GP PAGP A G+
Sbjct: 648 PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDG 707
Query: 204 LLNSHHAAAPAVSLVNNGP----------AALLPLPK----PAAPGTVIQTP------PF 243
A AP P AA LP PK A P +P
Sbjct: 708 AKGD--AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGL 765
Query: 244 VGAAAPPAPA---------APSPPAAP--APAAPAAAPPPPPPAPATLARPPG------- 285
G PP PA PS PA P A AP P PP PA A PPG
Sbjct: 766 TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825
Query: 286 ----------HPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAA 335
AGPP A PP N G+ GA A A GP G +G PG
Sbjct: 826 KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA--GPPGATGFPGAAGRV 883
Query: 336 AAPAPGVKAESPKRVVQAAP-----PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP 390
P P A P A P +T A P GP + P A P
Sbjct: 884 GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPG-ADGP 942
Query: 391 PPAPGTPTGLPKGAAG 406
APGTP P+G AG
Sbjct: 943 AGAPGTPG--PQGIAG 956
Score = 110 bits (274), Expect = 9e-24
Identities = 137/456 (30%), Positives = 158/456 (34%), Gaps = 94/456 (20%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
P P A GA G+ G P A AGP A+G PGA EP AG G GP
Sbjct: 786 PSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPG-ADGQPGAKGEPGDAG--AKGDAGP-- 840
Query: 105 PGPPSPRRPLVPAGPAPPAAKL-RPPPEGSAGSCAPVPA----AAAVAAGPEPAPAGPAK 159
PGP PAGP P + P +G+ GS P A AA GP P P+G A
Sbjct: 841 PGPAG------PAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP-PGPSGNAG 893
Query: 160 PAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVN 219
P GP A + G G GP GP PG+ PG G A S A PA +
Sbjct: 894 PPGPPGPAGKEG-GKGPRGETGPAGRPGEVGPPGPP----GPAGEKGSPGADGPAGAPGT 948
Query: 220 NGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP----PPPPP 275
GP + A V+ P G P P P P P+ A PP P
Sbjct: 949 PGPQGI------AGQRGVVGLPGQRGERG--FPGLPGPSGEPGKQGPSGASGERGPPGPM 1000
Query: 276 APATLARPPGH-----------------------------PAGPPTA--APAVPPPA--A 302
P LA PPG PAGPP A AP P P A
Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPA 1060
Query: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGP-------GAAAAAPAPGVKAESPKRVVQAAP 355
++G PA GP G G GP G G+K +Q P
Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPP 1120
Query: 356 -----PAAQ-TLAASGPAS----TAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAA 405
P Q ASGPA ++ G LP P P P T P G
Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPP 1180
Query: 406 GAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQ 441
G P ++G + LPQPPQ
Sbjct: 1181 G--PPGPPGPPGPPSAGFDFSF--------LPQPPQ 1206
Score = 108 bits (270), Expect = 3e-23
Identities = 143/497 (28%), Positives = 165/497 (33%), Gaps = 126/497 (25%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPA--------EGAPGAAPEPPPAG----RA 95
P A AG G +GSP GPA P +G PG P P+G R
Sbjct: 621 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG 680
Query: 96 RPGGGGPQRP-GPPSPR----------------RPLVPAGPAPPAAKLRPPPEGSAGSCA 138
PG G Q P GP PR P P P + P G+AG
Sbjct: 681 FPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG--L 738
Query: 139 PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTL 198
P P AGP+ A P K PGP PG GP PAGP A+
Sbjct: 739 PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA 798
Query: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLP----KPAAPGTVIQTPPFVGA---AAPPA 251
G P GPA P +P A G P GA A PP
Sbjct: 799 PGDRG-----EPGPP-------GPAGFAGPPGADGQPGAKG----EPGDAGAKGDAGPPG 842
Query: 252 PAAPSPPAAP-----APAA---------------PAAAPPPPPPAPATLARPPG--HPAG 289
PA P+ P P AP A P AA PP P+ A PPG PAG
Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAG 902
Query: 290 ----------------PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG--- 330
P P PP A + G PA AP GP G++GQ G
Sbjct: 903 KEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVG 962
Query: 331 -PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQ-------GA 382
PG PG+ S + Q A+ GP + GP + GA
Sbjct: 963 LPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG--LAGPPGESGREGAPGA 1020
Query: 383 LPSPA----------------AVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRAT 426
SP A PP APG P G P G G +S R T +G
Sbjct: 1021 EGSPGRDGSPGAKGDRGETGPAGPPGAPGAP-GAP-GPVGPAGKSGDRGETG-PAGPAGP 1077
Query: 427 LTPTVLAPRLPQPPQNP 443
+ P + R P PQ P
Sbjct: 1078 VGP--VGARGPAGPQGP 1092
Score = 97.1 bits (240), Expect = 8e-20
Identities = 133/457 (29%), Positives = 153/457 (33%), Gaps = 87/457 (19%)
Query: 54 AAGALGNHVVSGSPAGAAGAGPAAPAEGAPGA-APEPPPAGRARPG-------------- 98
A+G +G G P G G A G PG P P R PG
Sbjct: 213 ASGPMGPRGPPGPP-GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFS 271
Query: 99 --GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS----CAPVPAAA-----AVA 147
G GP P+ P P A + P G G AP PA A A
Sbjct: 272 GLDGAKGDAGPAGPKGE--PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATG 329
Query: 148 AGPEPAPAGPAKPAG-PAALAARAGPGP-GPGPGPGPGPGPGKPAGPGAAQTLNGSAALL 205
A P P GPA P G P A+ A+ GP GP GP G+P PG A
Sbjct: 330 AAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA---------- 379
Query: 206 NSHHAAAPAVSLVNNGPAALLPLPKPA--APGTVIQTPPFVGAAAPPAPAAPSPPAAP-- 261
AA PA N A P K A APG + P F GA P P P P P
Sbjct: 380 ---GAAGPA----GNPGADGQPGAKGANGAPG-IAGAPGFPGARGPSGPQGPGGPPGPKG 431
Query: 262 ------APAAPAAAPPPPPPAPATLARPPGHPAGP-----------PTAAPAVPPPAAAQ 304
AP + P P + PPG PAG PT P PP
Sbjct: 432 NSGEPGAPGSKGDTGAKGEPGPVGVQGPPG-PAGEEGKRGARGEPGPTGLPG--PPGERG 488
Query: 305 NGGSAGAAPAPAPAA-GGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA 363
GS G A A GPAG G PGP +P R +A P A+ L
Sbjct: 489 GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG------EAGRPGEAGLPGAKGLTG 542
Query: 364 S--GPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL----PKGAAGAVTQSLSRTPT 417
S P + GP Q P P PP A G + PKGAAG ++ R
Sbjct: 543 SPGSPGPDGKTGPPGPAGQDGRPGPPG-PPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601
Query: 418 ATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPG 454
+ + P P P + Q P G
Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAG 638
Score = 93.6 bits (231), Expect = 9e-19
Identities = 123/440 (27%), Positives = 146/440 (33%), Gaps = 74/440 (16%)
Query: 66 SPAGAAGAGPAAPA--EGAPGAAPEPPPAGRARPGG--GGPQRPGPPSPRRPLVPAG--- 118
S G + GP P+ G PG P P G P G G P GP PR P P G
Sbjct: 171 STGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNG 230
Query: 119 -------PAPPAAKLRPPPEGSAGSCAPVPAAAAVA--------AGPEPAPAGPAKPAGP 163
P P + P P+G+ G +P A + +G + A G A PAGP
Sbjct: 231 DDGEAGKPGRPGERGPPGPQGARG----LPGTAGLPGMKGHRGFSGLDGAK-GDAGPAGP 285
Query: 164 AALAARAGPGPGPGP-GPGPGPGP-GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
G PG GP PG G+P PG PA + N+G
Sbjct: 286 KGEPGSPGENGAPGQMGPRGLPGERGRPGAPG-------------------PAGARGNDG 326
Query: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLA 281
P P P P VGA P P P P PP PA A
Sbjct: 327 ATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP----QGVRGEPGPPGPAGAA 382
Query: 282 RPPGHPA--GPPTAAPAVPPPAAAQNGGSAGA-APAPAPAAGGPAGVSGQPG-PGAAAAA 337
P G+P G P A A P A G GA P+ GGP G G G PGA +
Sbjct: 383 GPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSK 442
Query: 338 PAPGVKAESPKRVVQAAP-PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
G K E VQ P PA + + + GP + P P
Sbjct: 443 GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA 502
Query: 391 -PPAPGTPTGL-----PKGAAGAVTQSLSRTPTATTSGIRA-TLTPTVLAPRLPQPPQNP 443
P P G PKG+ G R A G + T +P P P P
Sbjct: 503 GPKGPAGERGSPGPAGPKGSPG----EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558
Query: 444 TNIQNFQLPPGMVLVRSENG 463
PPG R + G
Sbjct: 559 AGQDGRPGPPGPPGARGQAG 578
Score = 92.8 bits (229), Expect = 2e-18
Identities = 113/378 (29%), Positives = 132/378 (34%), Gaps = 73/378 (19%)
Query: 63 VSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPP 122
V G GP PA G PG P +PG GP PGPP P P G P
Sbjct: 110 VEGPKGDTGPRGPRGPA-GPPGRDGIP-----GQPGLPGP--PGPPGPPGPPGLGGNFAP 161
Query: 123 AAKLR-----------PPPEGSAGSCA-PVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170
P P G +G P P A G + P P +P + R
Sbjct: 162 QLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRG 221
Query: 171 GPGPGPGPGPGPG-------PGPGKPAGPGAAQTLNGSAAL--LNSHHAAAPAVSLVNN- 220
PGP PG G PG P GP A+ L G+A L + H + +
Sbjct: 222 PPGP-PGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDA 280
Query: 221 GPAALLPLPKPAAPGTVIQTPPFVGAAAPPA----PAAPSPPAAPA-PAAPAAAPPPPPP 275
GPA P +P +PG P +G P P AP P A A AA PP P
Sbjct: 281 GPAG--PKGEPGSPGE-NGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT 337
Query: 276 APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP---- 331
P A PPG P G A P + GP GV G+PGP
Sbjct: 338 GP---AGPPGFPGAV---------------GAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379
Query: 332 GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA--AV 389
GAA A PG + + AP A P A GP G P P +
Sbjct: 380 GAAGPAGNPGADGQPGAKGANGAPG-----IAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434
Query: 390 PPPAPGTPTGLPKGAAGA 407
P APG+ KG GA
Sbjct: 435 EPGAPGS-----KGDTGA 447
Score = 82.4 bits (202), Expect = 2e-15
Identities = 77/245 (31%), Positives = 89/245 (36%), Gaps = 22/245 (8%)
Query: 67 PAGAAGA-GPAAPAEGAPGAAPEPPPAGR-ARPGG-GGPQRPGPPSPRRPLVPAGPAPPA 123
P+GA+G GP P G PG A P +GR PG G P R G P + GPA P
Sbjct: 987 PSGASGERGPPGPM-GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGP- 1044
Query: 124 AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG 183
P G+ G+ PV A E PAGPA P GP AGP GP
Sbjct: 1045 ----PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP-------QGPR 1093
Query: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
G+ G + + G P S GP+ P P P
Sbjct: 1094 GDKGE-TGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGK 1152
Query: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP-AGPPTAAPAVPPPAA 302
G P P P P A PP PP P PPG P AG + PP
Sbjct: 1153 DGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG----PPGPPSAGFDFSFLPQPPQEK 1208
Query: 303 AQNGG 307
A +GG
Sbjct: 1209 AHDGG 1213
Score = 35.8 bits (81), Expect = 0.23
Identities = 46/182 (25%), Positives = 52/182 (28%), Gaps = 30/182 (16%)
Query: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGH--PAGPPTAAPAVPPPAAAQNGGSA 309
P A P P P + P + P G P GP PA PP G
Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGP--RGPAGPPGRDGIPGQPG 139
Query: 310 GAAPAPAPAAGGPAGVSGQPGP--------GAAAAAPAPGVKAESPKRVVQAAPPAAQTL 361
P P GP G+ G P + PG S R + P A
Sbjct: 140 LPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQ 199
Query: 362 AASG----PASTAASMVIGPTMQGALPS-------------PAAVPPPAPGTPTGLPKGA 404
G P AS +GP P P PP P GLP G
Sbjct: 200 GFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP-GT 258
Query: 405 AG 406
AG
Sbjct: 259 AG 260
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 110 bits (274), Expect = 9e-24
Identities = 129/413 (31%), Positives = 138/413 (33%), Gaps = 73/413 (17%)
Query: 52 AAAAGALGNHVVSGSPAGAAGAGPAAPA-----EGAPGAAPEPPPAGRARPGGGGPQRPG 106
A AAGA GN G P A GP PA GAPGA E P G P G R
Sbjct: 338 AGAAGARGN---DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 394
Query: 107 PPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE--PAPAGPAKPAGP- 163
P +P P P P +GSAG AP A A GP P P G P GP
Sbjct: 395 PGTPGSPGPAGASGNPGTDGIPGAKGSAG--APGIAGAPGFPGPRGPPGPQGATGPLGPK 452
Query: 164 --------AALAARAGPGPGPGP-GPGPGPGP----GK-----------PAGPGAAQTLN 199
A GP PGP GP PGP GK P GP +
Sbjct: 453 GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP 512
Query: 200 GSAALLNSHHAAAPAVSLVNNGPAALLPLPK-----PAAPGTVIQTPPFVGAAAPPAPAA 254
G+ A P + GP+ L PK P PG P G P A
Sbjct: 513 GNRGFPGQDGLAGPKGAPGERGPSGLAG-PKGANGDPGRPGEP-GLPGARGLTGRPGDAG 570
Query: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG-------- 306
P P+ AP P PP P PG P P A + G
Sbjct: 571 PQGKVGPS-GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 629
Query: 307 ------GSAGAAPAPAPAA-GGPAGVSGQPGPGAAAAAPA-PGVKAESPKRVVQAAPPAA 358
G GAA P PA G G G PGP P PG E K Q P A
Sbjct: 630 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689
Query: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAV----PPPAPGTP-TGLPKGAAG 406
GP G SP A P PGTP T PKGA+G
Sbjct: 690 GAPGLVGPRGERG-------FPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 735
Score = 103 bits (256), Expect = 1e-21
Identities = 117/407 (28%), Positives = 138/407 (33%), Gaps = 65/407 (15%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAG----------AGPAAPAEGAPGAAPEPPPAG- 93
PR P A G LG +G P G AG GPA P +GAPG A E G
Sbjct: 436 PRGPPGPQGATGPLGPKGQTGEP-GIAGFKGEQGPKGEPGPAGP-QGAPGPAGEEGKRGA 493
Query: 94 RARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA 153
R PGG GP GPP R P P P+G+ G P A A +P
Sbjct: 494 RGEPGGVGPI--GPPGERG--APGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 549
Query: 154 PAGPAKPAGPAALAARAGP-GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAA 212
G G L R G GP GP PG GP Q G ++
Sbjct: 550 RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF----- 604
Query: 213 PAVSLVNNGPAALLPLPKPAAPGT--VIQTPPFVGAAAPPAPAAPS----PPAAPAPAAP 266
P N P P APG + GAA PP PA P+ AP P+
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664
Query: 267 AAAPPPPPPAPATLARP-----PGHPAGPPTAAPAVP---------------------PP 300
P PP P P +P PG P P P
Sbjct: 665 QGLPGPPGP-PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 723
Query: 301 AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP-GAAAAAPAPGVKAESPKRVVQAAPPAAQ 359
+G + PA P A GP G+ G PG GAA A G + + ++ + AP
Sbjct: 724 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 783
Query: 360 TLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAG 406
+GP P GA V PP P G +GA G
Sbjct: 784 GRGLTGPIGP-------PGPAGANGEKGEVGPPGPAGSAG-ARGAPG 822
Score = 102 bits (255), Expect = 2e-21
Identities = 110/368 (29%), Positives = 125/368 (33%), Gaps = 70/368 (19%)
Query: 68 AGAAGAGPAAPAEGAPGAAPEPPPAGRARPGG--GGPQRPGPPSPRRPLVPAGPAPPAAK 125
AG A G G G P PAG P G G P PG P P+ P GP P K
Sbjct: 191 AGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK 250
Query: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185
P +G AG P A GP+ A P P P R PG G PG
Sbjct: 251 --PGDDGEAGK--PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG 306
Query: 186 -PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV 244
G+ PG NGS + GP L PG +T P
Sbjct: 307 VKGESGSPGE----NGSPGPM---------------GPRGL--------PGERGRTGPAG 339
Query: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ 304
A A P P P P PA PG P P A P A
Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGG--------------PGFPGAPGAKGEAGPTGARGP 385
Query: 305 NGGSAGAAPAPAPAAGGPAGVSGQPG----PGAAAAAPAPGVKAESPKRVVQAAPPAAQT 360
G P + GPAG SG PG PGA +A APG+ A +P PP Q
Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI-AGAPGFPGPRGPPGPQ- 443
Query: 361 LAASGPASTAASMVIGPTMQGALPSPAAV-----PPPAPGTPTGLPKGAAGAVTQSLSRT 415
A+GP +GP Q P A P PG P G P+GA G + R
Sbjct: 444 -GATGP--------LGPKGQTGEPGIAGFKGEQGPKGEPG-PAG-PQGAPGPAGEEGKRG 492
Query: 416 PTATTSGI 423
G+
Sbjct: 493 ARGEPGGV 500
Score = 96.7 bits (239), Expect = 1e-19
Identities = 116/422 (27%), Positives = 142/422 (33%), Gaps = 67/422 (15%)
Query: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRA-RPGGGG 101
+ PR P A A G G G P +GP P G PG +P G A +PG G
Sbjct: 206 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGPPGKPGDDGEAGKPGKAG 264
Query: 102 PQRPGPPSPRR----PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGP----EPA 153
+ GPP P+ P P P + P +G+ G A P + P P
Sbjct: 265 ER--GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGE-AGAPGVKGESGSPGENGSPG 321
Query: 154 PAGP---------AKPAGPAALAARAG-PGPGPGPGP-GPGPGPGKPAGPGA-------- 194
P GP PAG A G PGP PGP GP GPG P PGA
Sbjct: 322 PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG 381
Query: 195 ---AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA 251
+ G + + PA + N G + A + P F G PP
Sbjct: 382 ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 441
Query: 252 PAAPSPPAAP-----------------APAAPAAAPPPPPPAPATLARPPGHPAGPPTAA 294
P + P P P A P P PA G P
Sbjct: 442 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 501
Query: 295 PAVPP--PAAAQNGGSAG----AAPAPAPAAGGPAGVSGQPG----PGAAAAAPAPGVKA 344
P PP A N G G A P AP GP+G++G G PG PG +
Sbjct: 502 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 561
Query: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA 404
+ + A P + + P GP QGA P + P P G P G
Sbjct: 562 LTGR--PGDAGPQGKVGPSGAPGEDGRPGPPGP--QGARGQPGVMGFPGPKGANGEP-GK 616
Query: 405 AG 406
AG
Sbjct: 617 AG 618
Score = 96.7 bits (239), Expect = 1e-19
Identities = 137/469 (29%), Positives = 154/469 (32%), Gaps = 74/469 (15%)
Query: 55 AGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPL 114
AGA G SGSP GP P G PG PAG A G Q PGP P P+
Sbjct: 302 AGAPGVKGESGSPGENGSPGPMGP-RGLPGERGRTGPAGAAGARGNDGQ-PGPAGPPGPV 359
Query: 115 VPAG----PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG----PAAL 166
PAG P P AK P G+ G P PAG + G P A
Sbjct: 360 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 419
Query: 167 AARAGPG----PG-PGPGPGPGP----GPGKPAG----PGAA-----QTLNGSAALLNSH 208
+ PG PG PGP PGP GP P G PG A Q G
Sbjct: 420 GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 479
Query: 209 HAAAPAVSLVNNG----PAALLPLPKP---AAPGTVIQTPPFVGAAAP---PAPAAPSPP 258
A PA G P + P+ P APG P G A P P PS
Sbjct: 480 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN-RGFPGQDGLAGPKGAPGERGPSGL 538
Query: 259 AAP--APAAPAAAPPPPPPAPATLARPPGH--------PAGPP--TAAPAVPPPAAAQNG 306
A P A P P P L PG P+G P P P P A+
Sbjct: 539 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598
Query: 307 GSAGAAPAPAPAAG--GPAGVSGQPG----------PGAAAAAPAPGVKAESPKRVVQAA 354
P P A G G AG G PG G AA PG + +R Q A
Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658
Query: 355 PPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSR 414
P + GP GP +G P VP A P+G G + S
Sbjct: 659 PGPSGFQGLPGPP--------GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP 710
Query: 415 TPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENG 463
TP P+ P P Q PPG+ + E G
Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG---PPGLQGMPGERG 756
Score = 96.3 bits (238), Expect = 1e-19
Identities = 123/416 (29%), Positives = 137/416 (32%), Gaps = 52/416 (12%)
Query: 52 AAAAGALGNHVVSGSPA--GAAGAGPAAPAEGAPGAAPEPPPAGRARPGG-----GGPQR 104
A A G +G G P G+ GA G PG P G + P G G P
Sbjct: 689 AGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 748
Query: 105 PGPPSPRRPLVPAGP----------APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAP 154
G P R AGP P A + G G P A A E P
Sbjct: 749 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP 808
Query: 155 AGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPA 214
GPA AG G PGP GP PG PG A+ G A A AP
Sbjct: 809 PGPAGSAGARGAPGERGETGPPGPAGFAGP-PGADGQPG-AKGEQGEAG--QKGDAGAP- 863
Query: 215 VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP 274
GP P P P V GA PP A P AA P + P P
Sbjct: 864 ------GPQGPSGAPGPQGPTGVTGPKGARGAQGPPG-ATGFPGAAGRVGPPGSNGNPGP 916
Query: 275 PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA----PAAGGPAGVSGQPG 330
P P P GP A PP A G G A P P GP+G G PG
Sbjct: 917 PGPP----GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 972
Query: 331 P-GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAV 389
P G A G+ + +R P GP+ P G P V
Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPGLP---------GPSGEPGKQG-APGASGDRGPPGPV 1022
Query: 390 PPPAPGTPTGLP--KGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
PP P G P +G+ GA R A G R T V AP P PP +P
Sbjct: 1023 GPPGLTGPAGEPGREGSPGA-DGPPGRDGAAGVKGDRGE-TGAVGAPGAPGPPGSP 1076
Score = 93.6 bits (231), Expect = 9e-19
Identities = 115/416 (27%), Positives = 140/416 (33%), Gaps = 73/416 (17%)
Query: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGG-G 101
+ P P A A GA G +G P A AGP A+G PGA E AG+ G G
Sbjct: 806 VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG-ADGQPGAKGEQGEAGQKGDAGAPG 864
Query: 102 PQRP-GPPSPRRPLVPAGP----------------------APPAAKLRPPPEGSAGSCA 138
PQ P G P P+ P GP PP + P P G
Sbjct: 865 PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG------ 918
Query: 139 PVPAAAAVAAGPEPA--PAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQ 196
P + GP+ A +GP AG L AGP PG PG GP GP Q
Sbjct: 919 --PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP-PGEKGEPG-DDGPSGAEGPPGPQ 974
Query: 197 TLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS 256
L G ++ P G LP P+ P G PP P P
Sbjct: 975 GLAGQRGIV-----GLPG----QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 1025
Query: 257 PPAAPA-----PAAPAAAPPPPPPAPATL---------ARPPGHPAGPPTAAPAVPPPAA 302
PA +P A PP A + PG P P + PA P
Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085
Query: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGP-GAAAAAPAPGVKAESPKR------VVQAAP 355
G + P G G+ G GP G A PG + R + P
Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1145
Query: 356 PAAQTLAASGPASTAASM----VIGPT-MQGALPSPAAVPPPAPGTPTGLPKGAAG 406
+ ASGPA + +GP+ GA P + PP P +G G AG
Sbjct: 1146 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSG-ETGPAG 1200
Score = 85.1 bits (209), Expect = 3e-16
Identities = 108/390 (27%), Positives = 127/390 (32%), Gaps = 99/390 (25%)
Query: 55 AGALGNHVVSGSPA-----GAAGAGPAAPAEGAPGAAPEPPPAGRARPGG--GGPQRPGP 107
AGA G SG+P G G A A+G PGA P AGR P G G P PGP
Sbjct: 860 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919
Query: 108 PSPRRPLVPAG------------------PA-PPAAKLRPPPEGSAGSCAP--------- 139
P P P G PA PP K P +G +G+ P
Sbjct: 920 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979
Query: 140 -----VPAAAAVAAGPE-PAPAG-PAKPAGPAALAARAGPGPGPGPG-PGPGPGPGKPAG 191
+P P P P+G P K P A R PGP PG GP PG+
Sbjct: 980 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 1039
Query: 192 PGA--------------------AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP 231
PGA A G+ S A P + G A P
Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099
Query: 232 AAPGTV--IQTPP----------------------FVGAAAPPAPAAPS-PPAAPAPAAP 266
+ P IQ P F G P P PS A PA P
Sbjct: 1100 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1159
Query: 267 AAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVS 326
+ PP P P G P PP ++G + A P P GP
Sbjct: 1160 SGPRGPPGPVG-----PSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP---P 1211
Query: 327 GQPGPG---AAAAAPAPGVKAESPKRVVQA 353
G PGPG +A A P K P + ++A
Sbjct: 1212 GPPGPGIDMSAFAGLGPREKGPDPLQYMRA 1241
Score = 75.1 bits (183), Expect = 3e-13
Identities = 103/334 (30%), Positives = 116/334 (34%), Gaps = 77/334 (23%)
Query: 113 PLVPAGPAPP-------AAKLRPPPEGSAGSCAPVPAAAAVAAGPE--PAPAGPAKPAGP 163
P +P G P A +P P+G G P GP+ P P GPA GP
Sbjct: 78 PEIPFGECCPICPTDLATASGQPGPKGQKGE----PGDIKDIVGPKGPPGPQGPAGEQGP 133
Query: 164 AA----LAARAGPGPG--------PG-PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA 210
+ PGP PG PGP PGP P G G N +A +
Sbjct: 134 RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGG----NFAAQMAGGFDE 189
Query: 211 AAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPA-APSPPAAPA----PAA 265
A G A L + P P +G PP PA AP P P
Sbjct: 190 KA--------GGAQLGVMQGPMGP---------MGPRGPPGPAGAPGPQGFQGNPGEPGE 232
Query: 266 PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG--GSAGAAPAP-APAAGGP 322
P + P P PPG P P A P A + G G GA P P G
Sbjct: 233 PGVSGPMGPRG------PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGV 286
Query: 323 AGVSGQPG-PGAAAAAPAPGVKAE--SPKRVVQAAPPAAQTL----AASGPASTAASMVI 375
G G PG GA A APGVK E SP P + L +GPA A
Sbjct: 287 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA----- 341
Query: 376 GPTMQGALPSPAAVPPPAPGTPTGLP--KGAAGA 407
G P PA PP P P G P GA GA
Sbjct: 342 GARGNDGQPGPAG--PPGPVGPAGGPGFPGAPGA 373
Score = 63.9 bits (154), Expect = 8e-10
Identities = 70/240 (29%), Positives = 79/240 (32%), Gaps = 42/240 (17%)
Query: 51 RAAAAGALGNHVVSG--SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGG--------G 100
+ A GA G+ G P G G EG+PGA P G A G G
Sbjct: 1006 KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVG 1065
Query: 101 GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160
P PGPP GPA P K +G G AG + P GP+ P
Sbjct: 1066 APGAPGPPG------SPGPAGPTGK-----QGDRGE-----------AGAQ-GPMGPSGP 1102
Query: 161 AGPAALAARAGPGPGPGPGPGPGP-GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVN 219
AG + GP G PG G G Q L G A+ PA
Sbjct: 1103 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA----- 1157
Query: 220 NGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA--PAAPAAAPPPPPPAP 277
GP+ P P P G PP P S PA P P PP PP P
Sbjct: 1158 -GPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1216
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 110 bits (274), Expect = 9e-24
Identities = 129/413 (31%), Positives = 138/413 (33%), Gaps = 73/413 (17%)
Query: 52 AAAAGALGNHVVSGSPAGAAGAGPAAPA-----EGAPGAAPEPPPAGRARPGGGGPQRPG 106
A AAGA GN G P A GP PA GAPGA E P G P G R
Sbjct: 269 AGAAGARGN---DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 325
Query: 107 PPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE--PAPAGPAKPAGP- 163
P +P P P P +GSAG AP A A GP P P G P GP
Sbjct: 326 PGTPGSPGPAGASGNPGTDGIPGAKGSAG--APGIAGAPGFPGPRGPPGPQGATGPLGPK 383
Query: 164 --------AALAARAGPGPGPGP-GPGPGPGP----GK-----------PAGPGAAQTLN 199
A GP PGP GP PGP GK P GP +
Sbjct: 384 GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP 443
Query: 200 GSAALLNSHHAAAPAVSLVNNGPAALLPLPK-----PAAPGTVIQTPPFVGAAAPPAPAA 254
G+ A P + GP+ L PK P PG P G P A
Sbjct: 444 GNRGFPGQDGLAGPKGAPGERGPSGLAG-PKGANGDPGRPGEP-GLPGARGLTGRPGDAG 501
Query: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG-------- 306
P P+ AP P PP P PG P P A + G
Sbjct: 502 PQGKVGPS-GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560
Query: 307 ------GSAGAAPAPAPAA-GGPAGVSGQPGPGAAAAAPA-PGVKAESPKRVVQAAPPAA 358
G GAA P PA G G G PGP P PG E K Q P A
Sbjct: 561 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620
Query: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAV----PPPAPGTP-TGLPKGAAG 406
GP G SP A P PGTP T PKGA+G
Sbjct: 621 GAPGLVGPRGERG-------FPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 666
Score = 103 bits (256), Expect = 1e-21
Identities = 117/407 (28%), Positives = 138/407 (33%), Gaps = 65/407 (15%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAG----------AGPAAPAEGAPGAAPEPPPAG- 93
PR P A G LG +G P G AG GPA P +GAPG A E G
Sbjct: 367 PRGPPGPQGATGPLGPKGQTGEP-GIAGFKGEQGPKGEPGPAGP-QGAPGPAGEEGKRGA 424
Query: 94 RARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA 153
R PGG GP GPP R P P P+G+ G P A A +P
Sbjct: 425 RGEPGGVGPI--GPPGERG--APGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480
Query: 154 PAGPAKPAGPAALAARAGP-GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAA 212
G G L R G GP GP PG GP Q G ++
Sbjct: 481 RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF----- 535
Query: 213 PAVSLVNNGPAALLPLPKPAAPGT--VIQTPPFVGAAAPPAPAAPS----PPAAPAPAAP 266
P N P P APG + GAA PP PA P+ AP P+
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595
Query: 267 AAAPPPPPPAPATLARP-----PGHPAGPPTAAPAVP---------------------PP 300
P PP P P +P PG P P P
Sbjct: 596 QGLPGPPGP-PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 654
Query: 301 AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP-GAAAAAPAPGVKAESPKRVVQAAPPAAQ 359
+G + PA P A GP G+ G PG GAA A G + + ++ + AP
Sbjct: 655 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 714
Query: 360 TLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAG 406
+GP P GA V PP P G +GA G
Sbjct: 715 GRGLTGPIGP-------PGPAGANGEKGEVGPPGPAGSAG-ARGAPG 753
Score = 102 bits (255), Expect = 2e-21
Identities = 110/368 (29%), Positives = 125/368 (33%), Gaps = 70/368 (19%)
Query: 68 AGAAGAGPAAPAEGAPGAAPEPPPAGRARPGG--GGPQRPGPPSPRRPLVPAGPAPPAAK 125
AG A G G G P PAG P G G P PG P P+ P GP P K
Sbjct: 122 AGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK 181
Query: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185
P +G AG P A GP+ A P P P R PG G PG
Sbjct: 182 --PGDDGEAGK--PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG 237
Query: 186 -PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV 244
G+ PG NGS + GP L PG +T P
Sbjct: 238 VKGESGSPGE----NGSPGPM---------------GPRGL--------PGERGRTGPAG 270
Query: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ 304
A A P P P P PA PG P P A P A
Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGG--------------PGFPGAPGAKGEAGPTGARGP 316
Query: 305 NGGSAGAAPAPAPAAGGPAGVSGQPG----PGAAAAAPAPGVKAESPKRVVQAAPPAAQT 360
G P + GPAG SG PG PGA +A APG+ A +P PP Q
Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI-AGAPGFPGPRGPPGPQ- 374
Query: 361 LAASGPASTAASMVIGPTMQGALPSPAAV-----PPPAPGTPTGLPKGAAGAVTQSLSRT 415
A+GP +GP Q P A P PG P G P+GA G + R
Sbjct: 375 -GATGP--------LGPKGQTGEPGIAGFKGEQGPKGEPG-PAG-PQGAPGPAGEEGKRG 423
Query: 416 PTATTSGI 423
G+
Sbjct: 424 ARGEPGGV 431
Score = 96.7 bits (239), Expect = 1e-19
Identities = 116/422 (27%), Positives = 142/422 (33%), Gaps = 67/422 (15%)
Query: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRA-RPGGGG 101
+ PR P A A G G G P +GP P G PG +P G A +PG G
Sbjct: 137 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGPPGKPGDDGEAGKPGKAG 195
Query: 102 PQRPGPPSPRR----PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGP----EPA 153
+ GPP P+ P P P + P +G+ G A P + P P
Sbjct: 196 ER--GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGE-AGAPGVKGESGSPGENGSPG 252
Query: 154 PAGP---------AKPAGPAALAARAG-PGPGPGPGP-GPGPGPGKPAGPGA-------- 194
P GP PAG A G PGP PGP GP GPG P PGA
Sbjct: 253 PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG 312
Query: 195 ---AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA 251
+ G + + PA + N G + A + P F G PP
Sbjct: 313 ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 372
Query: 252 PAAPSPPAAP-----------------APAAPAAAPPPPPPAPATLARPPGHPAGPPTAA 294
P + P P P A P P PA G P
Sbjct: 373 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 432
Query: 295 PAVPP--PAAAQNGGSAG----AAPAPAPAAGGPAGVSGQPG----PGAAAAAPAPGVKA 344
P PP A N G G A P AP GP+G++G G PG PG +
Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 492
Query: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA 404
+ + A P + + P GP QGA P + P P G P G
Sbjct: 493 LTGR--PGDAGPQGKVGPSGAPGEDGRPGPPGP--QGARGQPGVMGFPGPKGANGEP-GK 547
Query: 405 AG 406
AG
Sbjct: 548 AG 549
Score = 96.7 bits (239), Expect = 1e-19
Identities = 137/469 (29%), Positives = 154/469 (32%), Gaps = 74/469 (15%)
Query: 55 AGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPL 114
AGA G SGSP GP P G PG PAG A G Q PGP P P+
Sbjct: 233 AGAPGVKGESGSPGENGSPGPMGP-RGLPGERGRTGPAGAAGARGNDGQ-PGPAGPPGPV 290
Query: 115 VPAG----PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG----PAAL 166
PAG P P AK P G+ G P PAG + G P A
Sbjct: 291 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 350
Query: 167 AARAGPG----PG-PGPGPGPGP----GPGKPAG----PGAA-----QTLNGSAALLNSH 208
+ PG PG PGP PGP GP P G PG A Q G
Sbjct: 351 GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 410
Query: 209 HAAAPAVSLVNNG----PAALLPLPKP---AAPGTVIQTPPFVGAAAP---PAPAAPSPP 258
A PA G P + P+ P APG P G A P P PS
Sbjct: 411 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN-RGFPGQDGLAGPKGAPGERGPSGL 469
Query: 259 AAP--APAAPAAAPPPPPPAPATLARPPGH--------PAGPP--TAAPAVPPPAAAQNG 306
A P A P P P L PG P+G P P P P A+
Sbjct: 470 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529
Query: 307 GSAGAAPAPAPAAG--GPAGVSGQPG----------PGAAAAAPAPGVKAESPKRVVQAA 354
P P A G G AG G PG G AA PG + +R Q A
Sbjct: 530 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589
Query: 355 PPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSR 414
P + GP GP +G P VP A P+G G + S
Sbjct: 590 PGPSGFQGLPGPP--------GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP 641
Query: 415 TPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENG 463
TP P+ P P Q PPG+ + E G
Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG---PPGLQGMPGERG 687
Score = 96.3 bits (238), Expect = 1e-19
Identities = 123/416 (29%), Positives = 137/416 (32%), Gaps = 52/416 (12%)
Query: 52 AAAAGALGNHVVSGSPA--GAAGAGPAAPAEGAPGAAPEPPPAGRARPGG-----GGPQR 104
A A G +G G P G+ GA G PG P G + P G G P
Sbjct: 620 AGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 679
Query: 105 PGPPSPRRPLVPAGP----------APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAP 154
G P R AGP P A + G G P A A E P
Sbjct: 680 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP 739
Query: 155 AGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPA 214
GPA AG G PGP GP PG PG A+ G A A AP
Sbjct: 740 PGPAGSAGARGAPGERGETGPPGPAGFAGP-PGADGQPG-AKGEQGEAG--QKGDAGAP- 794
Query: 215 VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP 274
GP P P P V GA PP A P AA P + P P
Sbjct: 795 ------GPQGPSGAPGPQGPTGVTGPKGARGAQGPPG-ATGFPGAAGRVGPPGSNGNPGP 847
Query: 275 PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA----PAAGGPAGVSGQPG 330
P P P GP A PP A G G A P P GP+G G PG
Sbjct: 848 PGPP----GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 903
Query: 331 P-GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAV 389
P G A G+ + +R P GP+ P G P V
Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPGLP---------GPSGEPGKQG-APGASGDRGPPGPV 953
Query: 390 PPPAPGTPTGLP--KGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
PP P G P +G+ GA R A G R T V AP P PP +P
Sbjct: 954 GPPGLTGPAGEPGREGSPGA-DGPPGRDGAAGVKGDRGE-TGAVGAPGAPGPPGSP 1007
Score = 93.6 bits (231), Expect = 9e-19
Identities = 115/416 (27%), Positives = 140/416 (33%), Gaps = 73/416 (17%)
Query: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGG-G 101
+ P P A A GA G +G P A AGP A+G PGA E AG+ G G
Sbjct: 737 VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG-ADGQPGAKGEQGEAGQKGDAGAPG 795
Query: 102 PQRP-GPPSPRRPLVPAGP----------------------APPAAKLRPPPEGSAGSCA 138
PQ P G P P+ P GP PP + P P G
Sbjct: 796 PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG------ 849
Query: 139 PVPAAAAVAAGPEPA--PAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQ 196
P + GP+ A +GP AG L AGP PG PG GP GP Q
Sbjct: 850 --PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP-PGEKGEPG-DDGPSGAEGPPGPQ 905
Query: 197 TLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS 256
L G ++ P G LP P+ P G PP P P
Sbjct: 906 GLAGQRGIV-----GLPG----QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 956
Query: 257 PPAAPA-----PAAPAAAPPPPPPAPATL---------ARPPGHPAGPPTAAPAVPPPAA 302
PA +P A PP A + PG P P + PA P
Sbjct: 957 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016
Query: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGP-GAAAAAPAPGVKAESPKR------VVQAAP 355
G + P G G+ G GP G A PG + R + P
Sbjct: 1017 GDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1076
Query: 356 PAAQTLAASGPASTAASM----VIGPT-MQGALPSPAAVPPPAPGTPTGLPKGAAG 406
+ ASGPA + +GP+ GA P + PP P +G G AG
Sbjct: 1077 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSG-ETGPAG 1131
Score = 85.1 bits (209), Expect = 3e-16
Identities = 108/390 (27%), Positives = 127/390 (32%), Gaps = 99/390 (25%)
Query: 55 AGALGNHVVSGSPA-----GAAGAGPAAPAEGAPGAAPEPPPAGRARPGG--GGPQRPGP 107
AGA G SG+P G G A A+G PGA P AGR P G G P PGP
Sbjct: 791 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850
Query: 108 PSPRRPLVPAG------------------PA-PPAAKLRPPPEGSAGSCAP--------- 139
P P P G PA PP K P +G +G+ P
Sbjct: 851 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910
Query: 140 -----VPAAAAVAAGPE-PAPAG-PAKPAGPAALAARAGPGPGPGPG-PGPGPGPGKPAG 191
+P P P P+G P K P A R PGP PG GP PG+
Sbjct: 911 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970
Query: 192 PGA--------------------AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP 231
PGA A G+ S A P + G A P
Sbjct: 971 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030
Query: 232 AAPGTV--IQTPP----------------------FVGAAAPPAPAAPS-PPAAPAPAAP 266
+ P IQ P F G P P PS A PA P
Sbjct: 1031 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1090
Query: 267 AAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVS 326
+ PP P P G P PP ++G + A P P GP
Sbjct: 1091 SGPRGPPGPVG-----PSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP---P 1142
Query: 327 GQPGPG---AAAAAPAPGVKAESPKRVVQA 353
G PGPG +A A P K P + ++A
Sbjct: 1143 GPPGPGIDMSAFAGLGPREKGPDPLQYMRA 1172
Score = 73.9 bits (180), Expect = 7e-13
Identities = 98/313 (31%), Positives = 110/313 (35%), Gaps = 70/313 (22%)
Query: 127 RPPPEGSAGSCAPVPAAAAVAAGPE--PAPAGPAKPAGPAA----LAARAGPGPG----- 175
+P P+G G P GP+ P P GPA GP + PGP
Sbjct: 30 QPGPKGQKGE----PGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGE 85
Query: 176 ---PG-PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP 231
PG PGP PGP P G G N +A + A G A L + P
Sbjct: 86 PGTPGNPGPPGPPGPPGPPGLGG----NFAAQMAGGFDEKA--------GGAQLGVMQGP 133
Query: 232 AAPGTVIQTPPFVGAAAPPAPA-APSPPAAPA----PAAPAAAPPPPPPAPATLARPPGH 286
P +G PP PA AP P P P + P P PPG
Sbjct: 134 MGP---------MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRG------PPGP 178
Query: 287 PAGPPTAAPAVPPPAAAQNG--GSAGAAPAP-APAAGGPAGVSGQPG-PGAAAAAPAPGV 342
P P A P A + G G GA P P G G G PG GA A APGV
Sbjct: 179 PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 238
Query: 343 KAE--SPKRVVQAAPPAAQTL----AASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396
K E SP P + L +GPA A G P PA PP P
Sbjct: 239 KGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA-----GARGNDGQPGPAG--PPGPVG 291
Query: 397 PTGLP--KGAAGA 407
P G P GA GA
Sbjct: 292 PAGGPGFPGAPGA 304
Score = 63.9 bits (154), Expect = 8e-10
Identities = 70/240 (29%), Positives = 79/240 (32%), Gaps = 42/240 (17%)
Query: 51 RAAAAGALGNHVVSG--SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGG--------G 100
+ A GA G+ G P G G EG+PGA P G A G G
Sbjct: 937 KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVG 996
Query: 101 GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160
P PGPP GPA P K +G G AG + P GP+ P
Sbjct: 997 APGAPGPPG------SPGPAGPTGK-----QGDRGE-----------AGAQ-GPMGPSGP 1033
Query: 161 AGPAALAARAGPGPGPGPGPGPGP-GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVN 219
AG + GP G PG G G Q L G A+ PA
Sbjct: 1034 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA----- 1088
Query: 220 NGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA--PAAPAAAPPPPPPAP 277
GP+ P P P G PP P S PA P P PP PP P
Sbjct: 1089 -GPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 105 bits (263), Expect = 2e-22
Identities = 128/472 (27%), Positives = 161/472 (34%), Gaps = 86/472 (18%)
Query: 42 HLAPRTPEVRAAAAGALGNHVVSGS-----PAGAAG-AGPAAPAE-GAPGAAPEPPPAG- 93
H P+ P+ + + G G G P G G AGP E G GAA EP P G
Sbjct: 598 HPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGP 657
Query: 94 ---------RARPGGGGPQRPGPPSP------------------RRPLVPAGPAPPAAKL 126
+ G GPQ GPP P + P+ P GP +
Sbjct: 658 PGVPGSVGPKGSSGSPGPQ--GPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEK 715
Query: 127 RPPP-EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185
P G G A A PAGP GP G PG PGP
Sbjct: 716 GPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGM-PGIRGPPGPSGD 774
Query: 186 PGKP--AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
PGKP GP Q L G+ +V + +++L +P P P
Sbjct: 775 PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP--------- 825
Query: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAP----------PPPPPAP-----ATLARPPGHPA 288
P A P PP AP PA PA P PP PP P ++ PPG P
Sbjct: 826 -----PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPG-PR 879
Query: 289 GPP---TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP-GAAAAAPAPGVKA 344
GPP P PP + N + + P P GP G G PGP G PG
Sbjct: 880 GPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFST 939
Query: 345 ESPKRV---VQAAPPAAQTLAASGPAST-----AASMVIGPTMQGALPSPAAVPPPAPGT 396
+Q P G A + GP+ G+ + PP P
Sbjct: 940 SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG 999
Query: 397 PTGLPKGAAGAVTQSLSR--TPTATTSGIRATLTPTVLAPRLPQPPQNPTNI 446
P G P G+ + Q + + + + IR+ L+ P P PP T I
Sbjct: 1000 PPG-PPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTI 1050
Score = 80.5 bits (197), Expect = 8e-15
Identities = 111/422 (26%), Positives = 127/422 (30%), Gaps = 64/422 (15%)
Query: 94 RARPGGGGPQ-RPGPPSPRR-PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE 151
R PG G PGP R P P P P P+G GS +
Sbjct: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625
Query: 152 PAPAGPAKPAGPAALAARAGPG----PGPGPGPG-PG----------PGPGKPAGPGAAQ 196
P GP AGP + G PGP PG PG PGP P GP Q
Sbjct: 626 EGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQ 685
Query: 197 TLNGSAAL------LNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250
L G L P GP L P + P GA P
Sbjct: 686 GLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPA 745
Query: 251 AP----------AAPSPPAAPAPAAPAAAPPPP----PPAPATLARPPGHPAGPPTAAPA 296
P P P P+ P P P P L PG P P
Sbjct: 746 GPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPG--IKGEPG 803
Query: 297 VPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG-PGAAAAAPAPGVKAESPKRVVQAAP 355
P G S P P GP G G PG PGA A G+ +Q P
Sbjct: 804 APGKIVTSEGSSMLTVPGPP----GPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPP 859
Query: 356 PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP-------------PPAPGTPTGLPK 402
GP+ GP +G LP P P PP P P G PK
Sbjct: 860 GPPGPRGPPGPSIPGPPGPRGPPGEG-LPGPPGPPGSFLSNSETFLSGPPGPPGPPG-PK 917
Query: 403 GAAGAV----TQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLV 458
G G Q P +TSG ++ + P P PQ P + PG + +
Sbjct: 918 GDQGPPGPRGHQGEQGLPGFSTSG-SSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI 976
Query: 459 RS 460
S
Sbjct: 977 PS 978
Score = 60.5 bits (145), Expect = 9e-09
Identities = 111/463 (23%), Positives = 151/463 (32%), Gaps = 104/463 (22%)
Query: 67 PAGAAGA-GPAAPAEGAPG-------AAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAG 118
P G GA GPA PA G PG P PP R PG P PGP P +P
Sbjct: 831 PPGPPGAPGPAGPA-GLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGP 889
Query: 119 PAPPAAKLR---------------PPPEGSAGSCAP--------VPAAAAVAA------- 148
P PP + L P P+G G P +P + +
Sbjct: 890 PGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNL 949
Query: 149 -GPEPAPAGPAKPAG-------PAALAARAGPGPGPG------PGPGPGPGPGKPAGPGA 194
GP P P GP P G P AL +GP G GP PGP PG P PG+
Sbjct: 950 QGP-PGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGP-PGP-PGPPGPPGS 1006
Query: 195 AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF--------VGA 246
+ S + + ++ +G P P P T I F V +
Sbjct: 1007 ISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVS 1066
Query: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306
+ S ++ + A L + P GPP PP A+ +G
Sbjct: 1067 YLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPP------GPPGASGDG 1120
Query: 307 GSAGAAPAP--------APAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAA---- 354
A ++G G+ G PGP PG E +++ +
Sbjct: 1121 SLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPG-----LPGTSYEELLSLLRGSEFRG 1175
Query: 355 ---------PPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAA 405
PP S + S + +P P PP P P G P G +
Sbjct: 1176 IVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPG--PPGPPGPRG-PPGVS 1232
Query: 406 GAVTQSLSRTPTATTSGIRATLTPT-----VLAPRLPQPPQNP 443
GA+ + + S + + LT ++ P P PQ P
Sbjct: 1233 GALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGP 1275
Score = 33.9 bits (76), Expect = 0.86
Identities = 62/252 (24%), Positives = 75/252 (29%), Gaps = 101/252 (40%)
Query: 181 GPGPGPGKPAGPGAAQTLNGSAALLNSH---HAAAPAVSLVNNGPAALLPLPKPAAPGT- 236
GP PG P G L+ A L+S + ++ +S+ GP P P P PGT
Sbjct: 1106 GPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGP----PGP-PGLPGTS 1160
Query: 237 ------VIQTPPFVGAAAPPAPAAP-----------------------------SPPAAP 261
+++ F G PP P P PP P
Sbjct: 1161 YEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPP 1220
Query: 262 APAAPAAAPPPPPPAPATLAR-------------------------PPGHPA--GPPTAA 294
P P PP A AT A PPG P GPP +
Sbjct: 1221 GPPGP-RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDS 1279
Query: 295 PAVPPPAAAQNG---------------------------GSAGAAPAPAPAAG--GPAGV 325
+ A+ G GS GA A AAG GP G
Sbjct: 1280 RLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGT 1339
Query: 326 SGQPGPGAAAAA 337
PG G AAA
Sbjct: 1340 DIGPGGGYGAAA 1351
Score = 32.7 bits (73), Expect = 1.9
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 97 PGGGGPQRPGPPSPRRPLVPAGP-APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA 155
PG GP PGPP PR P +G A AA+ S P + GP P P
Sbjct: 1214 PGPPGP--PGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGP-PGPP 1270
Query: 156 GPAKPAGPAAL 166
GP P G + L
Sbjct: 1271 GPQGPPGDSRL 1281
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 105 bits (262), Expect = 2e-22
Identities = 112/354 (31%), Positives = 125/354 (35%), Gaps = 48/354 (13%)
Query: 64 SGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR--PGPPSPR-RPLVPAGPA 120
+G G G GP +G PG E P G P G G + GPP P+ +P
Sbjct: 593 NGERGGPGGPGP----QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG 648
Query: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAG-PGPGPGPG 179
PP +P G G A P GP AG L AG PGP G G
Sbjct: 649 PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708
Query: 180 PGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQ 239
PGP AG Q + G L S P +P PG
Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGS--------------PGPKGDKGEPGGPG-ADG 753
Query: 240 TPPFVGAAAPPAPAAPSPPAA-PAPAAPAAAPPPPPPAPATLARPPGHP-----AGPPTA 293
P G P P P PA P AP P +A P G P GPP
Sbjct: 754 VPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLP-----GIAGPRGSPGERGETGPP-- 806
Query: 294 APAVPPPAAAQNGGSAGAAPAPAP---AAGGPAGVSGQPGPGAAAAAPAP-GVKAE--SP 347
PA P A QNG G AP GGP GV+G PG A P P GVK E SP
Sbjct: 807 GPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP 866
Query: 348 KRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401
A P A+ L GP + + P G SP PP P TG P
Sbjct: 867 GGPGAAGFPGARGL--PGPPGSNGN----PGPPGPSGSPGKDGPPGPAGNTGAP 914
Score = 105 bits (262), Expect = 2e-22
Identities = 130/480 (27%), Positives = 149/480 (31%), Gaps = 138/480 (28%)
Query: 52 AAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPG------------- 98
A A G G ++G+P GAGP P G A P PP PG
Sbjct: 677 AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736
Query: 99 ---------GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAG 149
GGP G P P P GP P P + G +P A
Sbjct: 737 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGS 796
Query: 150 P-EPAPAGPAKPAG----------PAALAARAGP------------GPGPGPGPGPGPGP 186
P E GP PAG P R P GP G GP PGP
Sbjct: 797 PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGP 856
Query: 187 -------GKPAGPGA-----AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234
G P GPGA A+ L G + P+ S +GP P AP
Sbjct: 857 QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPG--PAGNTGAP 914
Query: 235 GTVIQTPPFVGAAAP---PAPAAPSPPAAPAP-------AAPAAAPPPPPPAPATLARP- 283
G+ + P A P +P A PP AP P A A PP P P P
Sbjct: 915 GSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQ 974
Query: 284 -------------------PGHPAGPPTAAPAVPPPAAAQNGGSAG-------------- 310
P P G P A P N GS G
Sbjct: 975 GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034
Query: 311 ---------------AAPAPAPAAG--------GPAGVSGQPGPGAAAAAPAP----GVK 343
P P AG GPAG +G PGP + AP P G K
Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDK 1094
Query: 344 AESPKRVVQAAPPAAQTLAASG-PASTAASMVIGPT-MQGALPSPAAVPPPAPGTPTGLP 401
E+ +R AA G P + A GP QGA+ SP P P P+G P
Sbjct: 1095 GETGER------GAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP 1148
Score = 105 bits (261), Expect = 3e-22
Identities = 127/415 (30%), Positives = 142/415 (34%), Gaps = 69/415 (16%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAA--PAEGAPGAAPEPPPAGR-----ARPGGG 100
P+ A A G G ++GSP G GPA A G GA P PAG R G G
Sbjct: 373 PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432
Query: 101 GPQR---PGPPSPRRPLVPAG-PAPPAAKLRPPPEGSAG--SCAPVPAAAAV-------- 146
P + G P PR AG P P AK +GS G +P AA
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRG 492
Query: 147 AAGPE--PAPAGPA------KPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTL 198
AGP P GPA PAGP A G PG GPG PG P GPG+
Sbjct: 493 PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPG-GPGMRGMPGSPGGPGSDGKP 551
Query: 199 NGSAALLNSHHAAAPAVSLVNNGPAAL-LPLPK--PAAPGTVIQTPPFVGAAAPPAPAAP 255
+ S P S P + P PK APG + P P
Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE------RGGPGGPGPQ 605
Query: 256 SPPAAPAPAAPAAAPPPP----------PPAPATLARPPGHPAGPP--TAAPAVPPPA-- 301
PP P P P PP P L PG GPP P P P
Sbjct: 606 GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPG-TGGPPGENGKPGEPGPKGD 664
Query: 302 AAQNGGSAGAAPAPAPAAGGPAGVSGQPG----------PGAAAAAPAPGVKAESPKRVV 351
A G G A AP GP G++G PG G AA PG + +
Sbjct: 665 AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724
Query: 352 QAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAG 406
Q P L + GP P GA P P P P G P G AG
Sbjct: 725 QGMPGERGGLGSPGPKGDKGE----PGGPGADGVPGKDGPRGPTGPIG-PPGPAG 774
Score = 98.2 bits (243), Expect = 4e-20
Identities = 113/400 (28%), Positives = 133/400 (33%), Gaps = 74/400 (18%)
Query: 65 GSPAGAAGAGPAAPA--EGAPGAAPEP----------------PPAGRARPGGGGPQRPG 106
GSP GP PA GAPG EP PP PGG GP G
Sbjct: 795 GSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPA--G 852
Query: 107 PPSPR-------RPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG--- 156
PP P+ P P P A+ P P GS G+ P + + P PAG
Sbjct: 853 PPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG 912
Query: 157 -PAKP--AGPAALAARAGPGPGPGP-GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAA 212
P P +GP A + G PG GP PGP AG A+ L G + +
Sbjct: 913 APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG 972
Query: 213 PAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA----------PAAPSPPAAPA 262
P +G L P P G A P P P
Sbjct: 973 PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKG 1032
Query: 263 PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322
+P P PGHP GPP P P + G S A PA AP GP
Sbjct: 1033 DRGENGSPGAPGA--------PGHP-GPP--GPVGPAGKSGDRGESGPAGPAGAP---GP 1078
Query: 323 AGVSGQPGP-------GAAAAAPAPGVKAESPKRVVQAAP----PAAQTLAASGPASTAA 371
AG G PGP G A G+K AP PA Q A P
Sbjct: 1079 AGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP 1138
Query: 372 SMVIGPT----MQGALPSPAAVPPPAPGTPTGLPKGAAGA 407
+GP+ G P + PP P G +G+ G+
Sbjct: 1139 RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRG-ERGSEGS 1177
Score = 95.1 bits (235), Expect = 3e-19
Identities = 130/468 (27%), Positives = 151/468 (32%), Gaps = 92/468 (19%)
Query: 54 AAGALGNHVVSGSPAGAAGAGPAAPA--EGAPGAAPEPPPAGRARPG-GGGPQRPGPPSP 110
AAGA GN GS GP A G+PGA E PAG PG G P + G P P
Sbjct: 316 AAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAG--SPGSNGAPGQRGEPGP 373
Query: 111 RRPLVPAG-PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG------- 162
+ G P PP P +G G A + A P PAG G
Sbjct: 374 QGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGE 433
Query: 163 PAALAARAGPGPGPGPGPGPGPG-------------PGKPAG---PGAAQTLNGSAALLN 206
P A+ PGP G PG PG+P PGAA G
Sbjct: 434 PGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAA----GERGAPG 489
Query: 207 SHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA----------AAPPAPAAPS 256
A P GPA P PA P P G +P P +
Sbjct: 490 FRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDG 549
Query: 257 PPAAPAPAAPAAAPPPPPPA-----PATLARP--------------PGHPAGPPTAAP-- 295
P P + P PP P+ P + P G P GP P
Sbjct: 550 KPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPG 609
Query: 296 ------AVPPPAAAQNGGSAGAAPAPA-------PAAGGPAGVSGQPG----PGAAAAAP 338
PP GG G P P GGP G +G+PG G A A
Sbjct: 610 KNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPG 669
Query: 339 APGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPT-MQGALPSPAAVPPPAPGTP 397
APG K ++ + P A G A GP +GA P PP A GTP
Sbjct: 670 APGGKGDAGAPGERGPPGLAGAPGLRGGAGPP-----GPEGGKGAAGPPG--PPGAAGTP 722
Query: 398 --TGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
G+P G G + + G A P PR P P P
Sbjct: 723 GLQGMP-GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGP 769
Score = 94.7 bits (234), Expect = 4e-19
Identities = 112/378 (29%), Positives = 132/378 (34%), Gaps = 45/378 (11%)
Query: 54 AAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQ-RPGPPSPRR 112
A G L + P G G + G+PG+ P G PG GP PGPP
Sbjct: 165 AVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG--EPGQAGPSGPPGPPGAIG 222
Query: 113 PLVPAG-------PAPPAAKLRPPPEGSAGSCAPVPAAAAVAA--GPEPAPAGPAKPAGP 163
P PAG P P + P P G G A +P + G + + P
Sbjct: 223 PSGPAGKDGESGRPGRPGERGLPGPPGIKGP-AGIPGFPGMKGHRGFDGRNGEKGETGAP 281
Query: 164 AALAARAGPGPGPGPGP-GPGPGP---GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVN 219
PG PGP GP P G+P PGAA A + P
Sbjct: 282 GLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP------ 335
Query: 220 NGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPAT 279
GP P +PG + P A +P + AP P P A A PP P P
Sbjct: 336 -GPPGTAGF--PGSPGAKGEVGP---AGSPGSNGAPGQRGEPGPQGHAGAQGPPGP-PGI 388
Query: 280 LARPPGHPAGPPTAAPAVPPPAAAQN-GGSAGAAPAPAPAAG----GPAGVSGQPGP--- 331
P G P P P A+ G AGA AP G G G G+PGP
Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE 448
Query: 332 -GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP--AA 388
G A PG K E K P A A+G A GP +P A
Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAG--ERGAPGFRGPAGPNGIPGEKGPA 506
Query: 389 VPPPAPGTPTGLPKGAAG 406
APG P G P+GAAG
Sbjct: 507 GERGAPG-PAG-PRGAAG 522
Score = 94.7 bits (234), Expect = 4e-19
Identities = 116/413 (28%), Positives = 136/413 (32%), Gaps = 74/413 (17%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR----ARPGGG 100
P P + G+ G+ G P AGP+ P G PGA PAG+ RPG
Sbjct: 181 PPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGP-PGPPGAIGPSGPAGKDGESGRPGRP 239
Query: 101 GPQ-RPGPPSPRRPL-VPAGPAPPAAKLRPPPEGSAGSCA----------PVPAAAAVAA 148
G + PGPP + P +P P + G G P A
Sbjct: 240 GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM 299
Query: 149 GPEPAPAGPAKPAGPAALAARAGPG-------PGPGPGPGPGPGPGKP-----AGPGAAQ 196
GP AP +P P A AR G PGP PG PG P GP +
Sbjct: 300 GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP 359
Query: 197 TLNGSAALLN----SHHAAA---PAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
NG+ HA A P +N P + PG P +GA P
Sbjct: 360 GSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPG----APGLMGARGP 415
Query: 250 PAPAAPSPP-----AAPAPAAPAAAPPPPPPAPATLARPPGHPA--------GPPTAAPA 296
P PA + A P A P P A PG P G P A
Sbjct: 416 PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGA 475
Query: 297 VPPPAAAQNGGSAG----AAPAPAPAAGGPAGVSGQPGP----GAAAAAPAPGVKAESPK 348
P AA G+ G A P P GPAG G PGP GAA GV
Sbjct: 476 NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGM 535
Query: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401
R + +P + GP P QG P PP P P G P
Sbjct: 536 RGMPGSPGGPGSDGKPGP----------PGSQGESGRPG---PPGPSGPRGQP 575
Score = 92.0 bits (227), Expect = 3e-18
Identities = 106/337 (31%), Positives = 119/337 (35%), Gaps = 56/337 (16%)
Query: 56 GALGNHVVSGSPAGAAGA-GPAAPA--EGAPGAAPEPPPAGRARPGG--GGPQRPGPPSP 110
G+ GN G P+G+ G GP PA GAPG+ P G A G G P GPP
Sbjct: 885 GSNGNPGPPG-PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA 943
Query: 111 RRPLVPAG----------PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160
PL AG P P + P P+G G A P P G
Sbjct: 944 PGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGL 1003
Query: 161 AGPAALAARAG-------PGPGPGPG----------PGPGPGPGKPAGPGAAQTLNGSAA 203
AG A R G PG PG PG PG P PG G A
Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPV----GPAG 1059
Query: 204 LLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA----PAAPSPPA 259
+ PA GPA P P P GAA P P P
Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPG 1119
Query: 260 APAPAAPAAAPPPPPPAPATLARPPGHPAGPP-----TAAPA-VPPPAAAQNGGSAGAAP 313
+P PA A P PA R P P+GPP + P + PP N G G+
Sbjct: 1120 SPGPAGQQGAIGSPGPAGP---RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG 1176
Query: 314 APA-PAAGGPAGVSGQPGP-----GAAAAAPAPGVKA 344
+P P GP G G PGP GAAA A G KA
Sbjct: 1177 SPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKA 1213
Score = 91.7 bits (226), Expect = 3e-18
Identities = 143/518 (27%), Positives = 168/518 (32%), Gaps = 75/518 (14%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP 107
P+ A A GA G +G+P G A GA P P G+ G GP PGP
Sbjct: 661 PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK---GAAGP--PGP 715
Query: 108 P-SPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP-APAGPAKPAGPAA 165
P + P + P P P+G G P A V P P GP P GPA
Sbjct: 716 PGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG-PGADGVPGKDGPRGPTGPIGPPGPAG 774
Query: 166 LAARAGPGPGPG-PG----------------PGPGPGPGKPAGPGAAQTLNGSAALLNSH 208
G G PG PG PGP PG P G A
Sbjct: 775 QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG 834
Query: 209 HAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAA-PPAPAAPSPPAA---PAPA 264
P V+ G P P P +P GAA P A P PP + P P
Sbjct: 835 EGGPPGVAGPPGGSGPAGP-PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893
Query: 265 APAAAP-PPPPPAPATLARPPGHP-AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG-- 320
P+ +P PP PA PG P P P + AP P AG
Sbjct: 894 GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGIT 953
Query: 321 GPAGVSGQPGPGAAAAAPAP-GVKAESPKRVV-----QAAPPAAQTLAASGPASTAA--- 371
G G++G PG +P P GVK ES K + PP Q L G A TA
Sbjct: 954 GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGL--PGLAGTAGEPG 1011
Query: 372 --------------SMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPT 417
G +G SP A P APG P P G G +S R +
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGA--PGAPGHPG--PPGPVGPAGKSGDRGES 1067
Query: 418 ATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQ 477
A P R PQ P + G ++ G P A
Sbjct: 1068 GPAGPAGA---PGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRG----FPGNPGAPGS 1120
Query: 478 AQAHAQPQTTMAPRPATP-----TSAPPVQISTVQAPG 510
Q +P PA P S PP + T PG
Sbjct: 1121 PGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPG 1158
Score = 88.6 bits (218), Expect = 3e-17
Identities = 122/431 (28%), Positives = 135/431 (31%), Gaps = 99/431 (22%)
Query: 75 PAAPAEGAPGAAPEPPPAGRARPGGGGPQ----RPGPPS-PRRPLVPAGPAPPAAKLRPP 129
P P P+PP A P G GPQ PGPP P R P P P + P
Sbjct: 77 PEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG 136
Query: 130 PEGSAGSCAPVP-----------AAAAVAAG---PEPAPAGPAKPAGPAALAARAGPGPG 175
P G SC P + VA G P PAGP P GP + G
Sbjct: 137 PPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGS 196
Query: 176 PG----PGPGPGPGPGKPAGPGAAQTLNGSAAL-LNSHHAAAPAVSLVNNGPAALLPLPK 230
PG PG GP P GP A +G A S P + P P
Sbjct: 197 PGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGI 256
Query: 231 PAAPGT--------------VIQTPPFVGAAAPP----APAAPSPPAAPA----PAAPAA 268
P PG P G P AP P AP P P A
Sbjct: 257 PGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGA 316
Query: 269 A------------PPPPPPAPATLARPPGHPAGPPTAAPAVPP---PAAAQNG-----GS 308
A P PP P A PG P PA P A Q G G
Sbjct: 317 AGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGH 376
Query: 309 AGAAPAPAP----------AAGGPAGVSGQPG-------PGAAAAAPAPGVK---AESPK 348
AGA P P GPAG+ G PG PG A A APG++ E K
Sbjct: 377 AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK 436
Query: 349 RVVQAAP-PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPA----------PGTP 397
+ P P + A P A G P +P A P P
Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496
Query: 398 TGLP--KGAAG 406
G+P KG AG
Sbjct: 497 NGIPGEKGPAG 507
Score = 77.8 bits (190), Expect = 5e-14
Identities = 94/330 (28%), Positives = 113/330 (34%), Gaps = 66/330 (20%)
Query: 48 PEVRAAAAGALGNHVVSGSP--------AGAAGAGPAAPAEGAPGAAPEPPPAG----RA 95
P+ A G G+ G P AG GA A G PG P P G
Sbjct: 922 PKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESG 981
Query: 96 RPGGGGPQ-RPGPPSPRRPLVPAGPAP-------PAAKLRPPPEGSAG-------SCAPV 140
+PG G GPP P+ AG A P + P +GS G + +P
Sbjct: 982 KPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPG 1041
Query: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG-PGPGKPAGPGAAQTLN 199
A GP P P GPA +G + AGP PGP G PGP P G
Sbjct: 1042 APGAPGHPGP-PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGER 1100
Query: 200 GSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA 259
G+A + H P P A P +PG Q +G+ P P P P+
Sbjct: 1101 GAAGIKG--HRGFPG------NPGA------PGSPGPAGQQGA-IGSPGPAGPRGPVGPS 1145
Query: 260 APAPAAPAAAPPPP--PPAPAT------LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGA 311
P + P P PP P PGHP P P PP
Sbjct: 1146 GPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP---GPPGPP-----------G 1191
Query: 312 APAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341
AP P G A ++G G A AP G
Sbjct: 1192 APGPCCGGVGAAAIAGIGGEKAGGFAPYYG 1221
Score = 72.0 bits (175), Expect = 3e-12
Identities = 82/302 (27%), Positives = 99/302 (32%), Gaps = 49/302 (16%)
Query: 128 PPPEGSAGSCA---PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPG-PGPG 183
P PE G C P P A P GP GP + PG PG PG
Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGI-----PGRNGDPGIPGQP 129
Query: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
PG P PG ++ + + + S V G A P
Sbjct: 130 GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYP---------------- 173
Query: 244 VGAAAPPAPAAPSPPAAP----APAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP 299
G A PP P P PP +P +P PP P A + PPG P + PA
Sbjct: 174 -GPAGPPGP--PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKD 230
Query: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG----------PGAAAAAPAPGVKAESPKR 349
+ + G P GPAG+ G PG G APG+K E+
Sbjct: 231 GESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLP 290
Query: 350 VVQAAPPAAQTLAASG----PASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAA 405
AP A G P A+ G GA S PP P G P G+
Sbjct: 291 GENGAPGPMGPRGAPGERGRPGLPGAAGARG--NDGARGSDGQPGPPGPPGTAGFP-GSP 347
Query: 406 GA 407
GA
Sbjct: 348 GA 349
Score = 58.2 bits (139), Expect = 4e-08
Identities = 73/271 (26%), Positives = 82/271 (30%), Gaps = 46/271 (16%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
P P+ AG G G+P G G P PG GP
Sbjct: 994 PPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP-- 1051
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPA 164
PGP P G + PA G AG AP PA + A GP+ P G G
Sbjct: 1052 PGPVGPAGKSGDRGESGPA--------GPAG--APGPAGSRGAPGPQ-GPRGDKGETGER 1100
Query: 165 ALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAA 224
A G PG PG P PG A G + S A P GP
Sbjct: 1101 GAAGIKGHRGFPG-------NPGAPGSPGPA----GQQGAIGSPGPAGP------RGPVG 1143
Query: 225 LLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP 284
P+ P P G + P P P P + P P P PP
Sbjct: 1144 ------PSGP------PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG----PP 1187
Query: 285 GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAP 315
G P P V A A GG AP
Sbjct: 1188 GPPGAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 105 bits (262), Expect = 2e-22
Identities = 131/513 (25%), Positives = 172/513 (33%), Gaps = 81/513 (15%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
PA P P A PPP P P PP P P P P+PP
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP--PPLPSPP---- 445
Query: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL-AARAGPGPGPGPGPGPGPG 185
PPP +P P A + P P P+ A AARAGP P P P
Sbjct: 446 -PPPAQEEQEESPPPVVPATCSRKRGRP--PLTPSQRAEREAARAGPEGTSPPTPTPSTA 502
Query: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245
G P + L N P VS A VI+TP
Sbjct: 503 TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVS---------------ARSSRVIKTPRRFM 547
Query: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP------AVPP 299
PP P P +P P PP P PA + PP P P T P ++
Sbjct: 548 DEDPPKP--PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
Query: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP--KRVVQAAPPA 357
+ P P PA P P A + PAP + P R Q P
Sbjct: 606 EPTFRWTSLTRELPPPPPA---------PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSE 656
Query: 358 AQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQ-SLSRTP 416
A V+ P GA +P PPPA +P A G SL R
Sbjct: 657 AHL--------KIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFA 708
Query: 417 TATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQM 476
T+ ++A ++P AP L PQ QLL Q Q+
Sbjct: 709 PVVTTPVKAEVSPHG-APALSNGPQT-------------------QAQLLQPLQALQTQL 748
Query: 477 QAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGT-PIIARQVTPTTIIKQVS------Q 529
QA PQ + P P +P PP++ + + G+ P+ + +++K+
Sbjct: 749 LPQALPPPQPQLQP-PPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKID 807
Query: 530 AQTTVQPSATLQRSPGVQPQLVLGGAAQTASLG 562
Q + +A++ SPG Q + V G Q + G
Sbjct: 808 QQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG 840
Score = 89.0 bits (219), Expect = 2e-17
Identities = 171/730 (23%), Positives = 230/730 (31%), Gaps = 160/730 (21%)
Query: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102
+AP P+ A G G + + A A + P P R RP P
Sbjct: 169 VAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRP----P 224
Query: 103 QRPGPPSPRRP--LVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAA---VAAGPEPAPAGP 157
RP P R+ +V A A K PPP PV GP P P P
Sbjct: 225 GRPAGPCRRKQQAVVVAEAAVTIPKPEPPPP-----VVPVKHQTGSWKCKEGPGPGPGTP 279
Query: 158 AKPA---------------------------------GPAALAARAGPGPG--------- 175
+ G +L +G G G
Sbjct: 280 RRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDV 339
Query: 176 PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG 235
P G G G G P Q L+ A +P
Sbjct: 340 PQRRVGSGQG-GSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEE 398
Query: 236 TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPA------G 289
+ PP A P+P P PP + +P P PPPPP +P L PP PA
Sbjct: 399 AKLPPPPLTPPA--PSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEES 456
Query: 290 PPTAAPAV-------PPPAAAQNG----------GSAGAAPAPAPAAGGPAGVSGQPGPG 332
PP PA PP +Q G++ P P+ A GGP S P
Sbjct: 457 PPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPK 516
Query: 333 AAAAAP------APGVKAES------PKRVVQAAPPAAQTLAAS---GPASTAASMVIGP 377
+ P V A S P+R + PP + S P T + V P
Sbjct: 517 STTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPV--P 574
Query: 378 TMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLP 437
+PSP P P P TP LP+ +S+ R PT + + L P P P
Sbjct: 575 QEPAPVPSPPRAPTP-PSTPVPLPE-----KRRSILREPTFRWTSLTRELPP---PPPAP 625
Query: 438 QPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTS 497
PP P+ PP S LL PQ ++ + + ++ + P P
Sbjct: 626 PPPPAPS-------PPPAPATSSRRPLLLRAPQFTPSEAHLKIY---ESVLTPPPLGAPE 675
Query: 498 AP-PVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAA 556
AP P +P P R V T + A P + SP P L G
Sbjct: 676 APEPEPPPADDSPAEP-EPRAVGRTNHLSLPRFAPVVTTP-VKAEVSPHGAPALSNGPQT 733
Query: 557 QTASLGTATAVQT-----------------GTPQRTVP---------GATTTSSAATETM 590
Q L A+QT +PQ+ P G+ S +
Sbjct: 734 QAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMF 793
Query: 591 ENVKKCKNFLSTL-----IKLASS-----GKQSTETAANVKELVQNLLDGKIEAEDFTSR 640
+K+ K L + K+A+S G Q E A VK++ G + +ED +
Sbjct: 794 SLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDR---GPVRSEDESVE 850
Query: 641 LYRELNSSPQ 650
RE S P+
Sbjct: 851 AKRERPSGPE 860
Score = 79.3 bits (194), Expect = 2e-14
Identities = 113/469 (24%), Positives = 159/469 (33%), Gaps = 95/469 (20%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
P P + A + N+ S P G GP P+ G+P + P G P
Sbjct: 1854 PPAPRSFSGARIKVPNYSPSRRPLGGVSFGPL-PSPGSPSSLTHHIPTV------GDPDF 1906
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPP-EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163
P PP R P P PP ++ PP + S P P + A P +G P GP
Sbjct: 1907 PAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTP---TSGELAPPGP 1963
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHH-----AAAPAVSLV 218
A P P P GP + +A L+ +A+LL + AA A+
Sbjct: 1964 A-------PSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSS 2016
Query: 219 NNGPA-ALLPLPKPAA-----PGTVIQTPPFVGAAAPPAP-------------------- 252
+ GP + P + P TV+ P +A P AP
Sbjct: 2017 HGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQ 2076
Query: 253 ---AAPSPPAAP--------APAAPAAAPPPPPPAP------ATLARPPGHPAGPPTAAP 295
+PP+ P A A PP P+ L P AGP +
Sbjct: 2077 QPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESL 2136
Query: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA-- 353
PP A + S G +PA A + G PG + PAP + +++
Sbjct: 2137 PPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNK 2196
Query: 354 --------------------APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAV---- 389
PP T++ + P T+ ++ GP + G LP V
Sbjct: 2197 LGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAP--TSWTLPPGPLL-GVLPVVGVVRPAP 2253
Query: 390 PPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQ 438
PPP P L G A Q++ +T SG P APRL +
Sbjct: 2254 PPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDE 2302
Score = 63.5 bits (153), Expect = 1e-09
Identities = 116/505 (22%), Positives = 165/505 (32%), Gaps = 97/505 (19%)
Query: 116 PAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175
P GP A L E +P P++ P P P + P
Sbjct: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPP 1844
Query: 176 PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG 235
P G P P A ++ +G+ + ++ + + V+ GP LP P +P
Sbjct: 1845 LRPDSGSAPPP-------APRSFSGARIKVPNYSPSRRPLGGVSFGP-----LPSPGSPS 1892
Query: 236 TVIQTPPFVGAAAPPAPAA----PSPPAAPAPAAPAAAPP---------PPPPAPATLAR 282
++ P VG PAP PSP A P + A+PP PPP + T
Sbjct: 1893 SLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALT 1952
Query: 283 PPGHPAGPPTAAPAVPPP---------AAAQNGGSAG-------------------AAPA 314
P PP AP+ PPP +G SA AA A
Sbjct: 1953 PTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGA 2012
Query: 315 PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG---PASTAA 371
+ GGP S + + P +P A P A + G + A
Sbjct: 2013 MGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEA 2072
Query: 372 SMVIGPTMQGALPS-PAAVPPPAPGT-------PTGLPK---------------GAAGAV 408
V P QG PS P V G P LP G AG
Sbjct: 2073 EAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPR 2132
Query: 409 TQSLSRTP-----TATTSGIRAT-LTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSEN 462
+SL P + + G+ A+ PT LP P ++ L P +
Sbjct: 2133 EESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAP----GVRVLSLGPAPEPPKPAT 2188
Query: 463 GQLLMIPQ--QALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTP 520
+++++ + Q +M + P P P PT +P S PG P++ V P
Sbjct: 2189 SKIILVNKLGQVFVKMAGEGEPVPPPVKQP-PLPPTISPTAPTSWTLPPG-PLLG--VLP 2244
Query: 521 TTIIKQVSQAQTTVQPSATLQRSPG 545
++ V A P TL S G
Sbjct: 2245 --VVGVVRPAPPPPPPPLTLVLSSG 2267
Score = 63.5 bits (153), Expect = 1e-09
Identities = 85/366 (23%), Positives = 114/366 (31%), Gaps = 56/366 (15%)
Query: 52 AAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPR 111
+A GA + G G A G P P RA G R PP
Sbjct: 2050 SATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPED- 2108
Query: 112 RPLVPAGPAPPAAK-LRPPPEGSAGSCAP-VPAAAAVAAGPEPAPAGPAKPAGPAALAAR 169
+P+ K L P +G AG +P A +A G +P+ A PA P A
Sbjct: 2109 ---LPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAW 2165
Query: 170 AGPGPGPGP-GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPL 228
PG GP P P KPA ++ ++ + V + G P+
Sbjct: 2166 LPGAPGVRVLSLGPAPEPPKPA----------TSKIILVNKLGQVFVKMAGEGEPVPPPV 2215
Query: 229 PKPAAPGTVIQTPPFVGAAAPPAPA------------APSPPAAPAPAAPAAAPPPPPPA 276
+P P T+ T P PP P AP PP P ++ P PP
Sbjct: 2216 KQPPLPPTISPTAP-TSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQ 2274
Query: 277 PATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAA 336
+ R P A P P ++G ++ P
Sbjct: 2275 AIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTP----------------------- 2311
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA--LPSPAAVPPPAP 394
PG+ + RV P L P A GP + + LP P PP P
Sbjct: 2312 -QVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVP 2370
Query: 395 GTPTGL 400
P L
Sbjct: 2371 DGPPDL 2376
Score = 49.3 bits (116), Expect = 2e-05
Identities = 170/804 (21%), Positives = 241/804 (29%), Gaps = 154/804 (19%)
Query: 95 ARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAP 154
A GGG PG R P P G + G G+ A A G P
Sbjct: 3 AAAGGGSCPGPGSARGRFPGRPRGAGGGGGR------GGRGNGAERVRVALRRGGGATGP 56
Query: 155 AGPAKPAGPAALAARAG------------PGP----GPGPGPGPGPGPGKPAGPGAAQTL 198
G A+P AL G GP G G G G G GP + P +
Sbjct: 57 GG-AEPGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSD 115
Query: 199 NGS-----AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPA 253
S + A ++ P + T PP + AP P
Sbjct: 116 GESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPK 175
Query: 254 APSPPA------------------APAPAAPAAAPPPPPPAPATLARPPGHPAGP----- 290
P+ A AP AP + P + RPPG PAGP
Sbjct: 176 TPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQ 235
Query: 291 ----------PTAAPAVPPPAAA---QNGG---SAGAAPAP-APAAGGPAGVSGQPGPGA 333
P PPP Q G G P P P GG + G+ G G
Sbjct: 236 QAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGR 295
Query: 334 AAAAPAPGV-KAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP-----TMQGALP--- 384
P V K S + V+ + + G S P + QG P
Sbjct: 296 GRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWK 355
Query: 385 -SPAAVPPPAPGTPTGLPKGAAGAVTQ--SLSRTPTATTSGIRATLTPTVLAPRLPQPPQ 441
+ K G + +++ A L P L P P PP
Sbjct: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
Query: 442 NPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPV 501
LPP P + P P P S PP+
Sbjct: 416 --------PLPP--------------------------PSTSPPPPLCPPPPPPVSPPPL 441
Query: 502 QISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASL 561
P P P ++ ++ V P AT R G P A + A+
Sbjct: 442 -------PSPP-------PPPAQEEQEESPPPVVP-ATCSRKRGRPPLTPSQRAEREAAR 486
Query: 562 G--TATAVQTGTPQRTVPGATTTS-SAATETMENVKKCKNFLSTLIKLASSGKQST---- 614
T+ T TP G S + A ++ +K + F+ ++ SS T
Sbjct: 487 AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
Query: 615 ---ETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQ--LTP 669
+ K V +L I + + S P+ P LP R+ L
Sbjct: 547 MDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
Query: 670 DSAAFIQQSQQQPPPPTS----QATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLT 725
+ + +++ PPPP + A + A SS T + A S+
Sbjct: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVL 666
Query: 726 QPTQVGVGKQGQPTPLVIQQ---PPKPGALIRPPQVTLTQ------TPMVALRQPHNRIM 776
P +G + +P P P+P A+ R ++L + TP+ A PH
Sbjct: 667 TPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726
Query: 777 LTTPQQIQLNPLQPVPVVKPAVLP 800
L+ Q Q LQP+ ++ +LP
Sbjct: 727 LSNGPQTQAQLLQPLQALQTQLLP 750
Score = 33.5 bits (75), Expect = 1.1
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 166 LAARAGPGPGPGPGPGPGPGPGKPAGPG 193
+AA AG G PGPG G PG+P G G
Sbjct: 1 MAAAAGGGSCPGPGSARGRFPGRPRGAG 28
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 104 bits (260), Expect = 4e-22
Identities = 179/712 (25%), Positives = 251/712 (35%), Gaps = 102/712 (14%)
Query: 50 VRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPS 109
V +AG G H + PA A AP G P P P P P
Sbjct: 1239 VHLVSAG--GQHHLISQPAHVALIQAVAPTPG-------PTPVS-VLPSSTPSTTPAPTG 1288
Query: 110 PRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAA-LAA 168
PL AA PP + + A G P P P P++ L A
Sbjct: 1289 LSLPL--------AANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPA 1340
Query: 169 RAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALL-- 226
P P PG P P G P TL LL H+ +P VS G A L
Sbjct: 1341 VLNPRPTLTPGRLPTPTLGTARAPMPTPTL--VRPLLKLVHSPSPEVSASAPGAAPLTIS 1398
Query: 227 -PLPKPAA-PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPP-PPPAPATLARP 283
PL P++ PG P ++ +P + + + + P + P P PA A L P
Sbjct: 1399 SPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIP 1458
Query: 284 PGHP----AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA 339
P A P +V PP A AP P + P+G S A A
Sbjct: 1459 ISAPLTVSASGPALLTSVTPPLAPV------VPAAPGPPSLAPSGASPSASALTLGLATA 1512
Query: 340 PGVKA-ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPT 398
P + + ++P + AP ++ + + A S V+ P A P P+A P PAP +
Sbjct: 1513 PSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSA-PNPAPAQAS 1571
Query: 399 GLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLV 458
L A + +Q+L+ TP A + + +LAP P PP P LP
Sbjct: 1572 LL--APASSASQALA-TPLAPMAAPQTA----ILAPS-PAPPLAP-------LP------ 1610
Query: 459 RSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQV 518
++ P A + A + P MAP TS S V AP TP++A
Sbjct: 1611 -------VLAPSPGAAPVLASSQT-PVPVMAPSSTPGTSL--ASASPVPAP-TPVLAPSS 1659
Query: 519 TPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPG 578
T T + V + + TL +P + P L +QT SLG TG PQ P
Sbjct: 1660 TQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLG------TGNPQGPFPT 1713
Query: 579 ATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFT 638
T + + A+ + + +L G T + A L G A T
Sbjct: 1714 QTLSLTPASSLVPTPAQ----TLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLT 1769
Query: 639 SRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPP-PTSQATTALTAVV 697
PA + + A +Q P P PT A T +
Sbjct: 1770 ---------------------LAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLAL 1808
Query: 698 LSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKP 749
+S Q A + ++ V SA L +T +++ V K T + PP P
Sbjct: 1809 APASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSP 1860
Score = 100 bits (248), Expect = 1e-20
Identities = 188/804 (23%), Positives = 276/804 (34%), Gaps = 106/804 (13%)
Query: 75 PAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGP------APPAAKLRP 128
P AP P P P P A+P G + P S PAGP PP L P
Sbjct: 1015 PRAPLGPVP-VRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLP 1073
Query: 129 PPEGSAGSCAPV-PAAAAVAAGPE--PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGP- 184
P + ++GS V P+ V +G P P KP PA + R P P PG P
Sbjct: 1074 PLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPV--RLSPAPPPGSSSLLKPL 1131
Query: 185 --GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242
PG P AA T + + A +P P PA ++ P
Sbjct: 1132 TVPPGYTFPPAAATTTSTTTA----------------TATTTAVPAPTPAPQRLILS--P 1173
Query: 243 FVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAA 302
+ A P A P A P + G AV P
Sbjct: 1174 DMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRP 1233
Query: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGA--AAAAPAPGVKAESPKRVVQAAPPAAQT 360
Q +AGG + QP A A AP PG +P V+ ++ P+ T
Sbjct: 1234 LQRN------VVHLVSAGGQHHLISQPAHVALIQAVAPTPG---PTPVSVLPSSTPST-T 1283
Query: 361 LAASGPASTAASMVIGPTM----------------QGALPSPAAVPPPAPGTPTGLPKGA 404
A +G + A+ + PTM G P P P P P + +GLP
Sbjct: 1284 PAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPS-SGLPAVL 1342
Query: 405 AGAVTQSLSRTPTATTSGIRATL-TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENG 463
T + R PT T RA + TPT++ P L + + + S
Sbjct: 1343 NPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLH 1402
Query: 464 QLLMIPQQALAQMQAQAHAQPQTTMAPRPATP-TSAPPVQI-STVQAPGT-PIIARQVTP 520
+P A + M + + ++ + P +S+ P+ + +T+ AP + P+ P
Sbjct: 1403 VPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAP 1462
Query: 521 TTIIKQVSQAQTTVQP--SATLQRSPGVQPQLVLGGAAQTAS---LGTATAVQTGTPQRT 575
T+ T+V P + + +PG P L GA+ +AS LG ATA + Q
Sbjct: 1463 LTVSASGPALLTSVTPPLAPVVPAAPG-PPSLAPSGASPSASALTLGLATAPSLSSSQTP 1521
Query: 576 ------------VPGATTT-----------SSAATETMENVKKCKNFLSTLIKLASSGKQ 612
VPG +T +SA + ++L+ ASS Q
Sbjct: 1522 GHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQ 1581
Query: 613 STETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSA 672
+ T Q + A +P P P L S + + P S
Sbjct: 1582 ALATPLAPMAAPQTAILAPSPAPPLAPLPV----LAPSPGAAPVLASSQTPVPVMAPSST 1637
Query: 673 AFIQQSQQQP-PPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQP---PVLSLTQPT 728
+ P P PT + T +L + V A+T T AL P P L + P+
Sbjct: 1638 PGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPS 1697
Query: 729 Q---VGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQL 785
Q +G G P P +L+ P TL+ P L + P
Sbjct: 1698 QTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPA 1757
Query: 786 NPLQPVPVVKPAVLPGTKALSAVS 809
+P+ P P + P + + S ++
Sbjct: 1758 SPVGPAPAHTLTLAPASSSASLLA 1781
Score = 98.6 bits (244), Expect = 3e-20
Identities = 145/528 (27%), Positives = 196/528 (37%), Gaps = 85/528 (16%)
Query: 47 TPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPG 106
+PEV A+A GA + S ++ GPA+ P ++P P
Sbjct: 1382 SPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSV-------- 1433
Query: 107 PPSPRRPL-VPAG-PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPA 164
P S P+ VP PAP +A L P A PA + P AP PA P P+
Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLT-SVTPPLAPVVPAAPGPPS 1492
Query: 165 ALAARAGP-------GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL 217
+ A P G P PG P + LNS A A + L
Sbjct: 1493 LAPSGASPSASALTLGLATAPSLSSSQTPGHPL---LLAPTSSHVPGLNSTVAPACSPVL 1549
Query: 218 VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP------- 270
V PA+ L P P+AP P A+ APA+ + A P AP AAP
Sbjct: 1550 V---PASALASPFPSAPN------PAPAQASLLAPASSASQALATPLAPMAAPQTAILAP 1600
Query: 271 -PPPPPAP-ATLARPPGHPAGPPTAAPAVPPPAAAQNG------GSAGAAPAPAPAAGGP 322
P PP AP LA PG A P A+ P P A + SA PAP P
Sbjct: 1601 SPAPPLAPLPVLAPSPG--AAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPS 1658
Query: 323 AGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG------ 376
+ + P P P+P + + + + + AP A TL S P+ T S+ G
Sbjct: 1659 STQTMLPAP-----VPSP-LPSPASTQTLALAPALAPTLGGSSPSQT-LSLGTGNPQGPF 1711
Query: 377 PTMQGAL-PSPAAVPPP------APGTPTG----------------LPKGAAGAVTQSLS 413
PT +L P+ + VP P APG P G P G A A T +L+
Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLA 1771
Query: 414 RTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQAL 473
++ + A++ L+P P P P Q L P + L++
Sbjct: 1772 PASSSASLLAPASVQTLTLSP-APVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGA 1830
Query: 474 AQMQAQAHAQ-PQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTP 520
A + ++ P + P T S PP ST + G P RQ P
Sbjct: 1831 APLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPP 1878
Score = 85.1 bits (209), Expect = 3e-16
Identities = 99/358 (27%), Positives = 135/358 (37%), Gaps = 46/358 (12%)
Query: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPP-----SPRRPLVPAGPA 120
SP + A+P AP P P A P Q P +P+ ++ PA
Sbjct: 1546 SPVLVPASALASPFPSAPN--PAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPA 1603
Query: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE-PAPA-GPAKPAGPAALAARAGPGPGPGP 178
PP A L AP P AA V A + P P P+ G + +A P P P
Sbjct: 1604 PPLAPLPV--------LAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVL 1655
Query: 179 GPG------PGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPA--VSLVNNGPAALLPLPK 230
P P P P P + QTL + AL + ++P+ +SL P P
Sbjct: 1656 APSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQT 1715
Query: 231 ----PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA-TLARPPG 285
PA+ +++ TP + AP P P+ + APA P A P PAPA TL P
Sbjct: 1716 LSLTPAS--SLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPA 1773
Query: 286 HPAGPPTAAPAVP-----PPAAAQNGGSAGAAPAPAPAAG-GPAGVSGQPGPGAAAAAPA 339
+ A +V P G +A A APA+ PA + A+ AAP
Sbjct: 1774 SSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPL 1833
Query: 340 PGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTP 397
P + V P TL + P+ + + G P P PPP P +P
Sbjct: 1834 PVTMVS--RLPVSKDEPDTLTLRSGPPSPPSTATSFGG------PRPRRQPPPPPRSP 1883
Score = 65.1 bits (157), Expect = 3e-10
Identities = 115/449 (25%), Positives = 164/449 (36%), Gaps = 66/449 (14%)
Query: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGA--PGAAPE------PPPAGR 94
L P P + AG++ N +P A G EG P E PP A
Sbjct: 2602 LTPSAPSL-TLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAAS 2660
Query: 95 ARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAP 154
P Q P + P ++ +P +A AP +++A ++ P+P
Sbjct: 2661 DEP----LQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSP 2716
Query: 155 AGPAKPAGPAALAARAGPGPG-PGPGPGP---GPGPGKPAGPGAAQTL-------NGSAA 203
A P + A + R G G G PG PGP PG+ + L G+A+
Sbjct: 2717 ARPPRRRTSADVEIR-GQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAAS 2775
Query: 204 LL---NSHHAAAPAVSLVN--NGPAALLPL--PKPAAPGTVIQTP---PFVGAAAPPAPA 253
L S +A+P V +GP + P+ P AAP + + TP PF+ A
Sbjct: 2776 TLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFI--ARRHIEL 2833
Query: 254 APSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV-PPPAAAQNGGSAGAA 312
+ +P A PP RPP P A V P++ G + GA
Sbjct: 2834 GVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGAD 2893
Query: 313 PAPAPAAGGPAGVSGQPG--PGAAAAAPAPGVKAESP-----KRVVQAAPPAAQTLAASG 365
P P P A +P PG P P V +P ++ + PP A+ L G
Sbjct: 2894 PVPGPETLIVADPVLEPQLIPGPQPLGPQP-VHRPNPLLSPVEKRRRGRPPKARDLPIPG 2952
Query: 366 PASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRA 425
S+A PPP P T LP L PTAT +
Sbjct: 2953 TISSAGD---------GNSESRTQPPPHPSPLTPLP---------PLLVCPTATVANTVT 2994
Query: 426 TLTPTVLAPRLP--QPPQNPTNIQNFQLP 452
T+T + P+ +PP+NP + + QLP
Sbjct: 2995 TVTISTSPPKRKRGRPPKNPPSPRPSQLP 3023
Score = 60.8 bits (146), Expect = 7e-09
Identities = 165/770 (21%), Positives = 262/770 (34%), Gaps = 144/770 (18%)
Query: 171 GPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK 230
GPG G G G G + + A G+ A A N+ P ++ +
Sbjct: 2363 GPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQG-ANHTP--VISAHQ 2419
Query: 231 PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290
+ T + P PAP P P A APAA A P P AP ++ P P
Sbjct: 2420 TRSTTTPPRCSPARERVPRPAPR-PRPTPASAPAAIPALVPVPVSAPVPISAPNPITILP 2478
Query: 291 PTAAPAVPPPAAAQNGGSAGAAPAPA----PAAGGPAG-----------VSGQPG-PGAA 334
P+ PPP+ S P PA PA P + G P P +A
Sbjct: 2479 VHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISA 2538
Query: 335 AAAPAP-GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPA 393
+ P G++ E+ A P + LA+ + T++ ++ P + LP + P +
Sbjct: 2539 SVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPP--KDLLPVAVEILPVS 2596
Query: 394 PGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPP 453
++LS TP+A + + A P P + T LP
Sbjct: 2597 ---------------EKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLT---VLPE 2638
Query: 454 G--MVLVRSENGQLLMIPQQALAQ-MQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPG 510
G + L SE+ L + P A + +Q A + TPTS+P + P
Sbjct: 2639 GEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSP-------EKPQ 2691
Query: 511 TPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTG 570
+ A P+T + T P SP P+ + GT Q
Sbjct: 2692 ELVTAEVAAPST------SSSATSSPEGP---SPARPPRRRTSADVEIRGQGTGRPGQPP 2742
Query: 571 TPQ--RTVPGATTTSSAATETMENVKKCKNFLSTLI-----KLASSGKQSTETAANVKEL 623
P+ R +PG T E + ++ + STL+ AS G S + + +
Sbjct: 2743 GPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPES- 2801
Query: 624 VQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKR---------------SLPALRQLT 668
+ G EA +S P P PF+ R AL +T
Sbjct: 2802 -SPPIGGPCEA--------APSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAIT 2852
Query: 669 PDSAAFIQQSQQQPPPPTSQATTALTAV--VLSSSVQ-RTAG-------KTAATVTSALQ 718
P + +++ + +PP A V SS+++ +T G +T L+
Sbjct: 2853 PPA---VKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLE 2909
Query: 719 PPVLSLTQPTQVGVGKQGQPTPLV----------------------------------IQ 744
P ++ QP +G +P PL+ Q
Sbjct: 2910 PQLIPGPQP--LGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQ 2967
Query: 745 QPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKA 804
PP P L P + + T VA I + P++ + P + P +P+ LP
Sbjct: 2968 PPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDR 3027
Query: 805 LSAVSAQAAAAQKNKLKEPGG---GSFRDDDDINDVASMAGVNLSEESAR 851
S ++ + + + G GS D+D + +A + L E R
Sbjct: 3028 DSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGMR 3077
Score = 57.8 bits (138), Expect = 6e-08
Identities = 70/263 (26%), Positives = 96/263 (36%), Gaps = 36/263 (13%)
Query: 46 RTPEVRAAAAGALGNHVVSGSPAGAAGA--GPAAPAEGAPGAAPEPPPA----------- 92
+TP A + G + S SP A P++ P P P P+
Sbjct: 1626 QTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP 1685
Query: 93 ------GRARP------GGGGPQRPGPP-----SPRRPLVPAGPAPPAAKLRPPPEGSAG 135
G + P G G PQ P P +P LVP PA + PP G
Sbjct: 1686 ALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPT-PAQTLSLAPGPPLGPTQ 1744
Query: 136 SCAPVPAAAAVAAGPE-PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGA 194
+ + PA A P PAPA A ++ A+ P P P P GP A
Sbjct: 1745 TLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVP--TLGPAA 1802
Query: 195 AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAA 254
AQTL + A S + A ++ + +G A L P + + + PP+P
Sbjct: 1803 AQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSP-- 1860
Query: 255 PSPPAAPAPAAPAAAPPPPPPAP 277
PS + P PPPPP +P
Sbjct: 1861 PSTATSFGGPRPRRQPPPPPRSP 1883
Score = 47.8 bits (112), Expect = 6e-05
Identities = 146/687 (21%), Positives = 213/687 (31%), Gaps = 105/687 (15%)
Query: 78 PAEGAPGAAPEPPPAGRARPGGGGPQRPGPPS---------------PRRPL-VPAGPAP 121
P P A PPPA P GPPS P L A +P
Sbjct: 2502 PPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASP 2561
Query: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK----PAGPAALAARAGPGPGPG 177
+ +L S + VP + E P P+ P +L AG P
Sbjct: 2562 ESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAP-SLTLEAGSIPNGQ 2620
Query: 178 PGPGPGPGPGK-----PAG---PGAAQTLNG-----SAALLNSHHAAAPAVSLVNNGPAA 224
P G P G P NG SAA A A
Sbjct: 2621 EQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEA 2680
Query: 225 LLPLPKPAAPGTVIQ---TPPFVGAAAPPAPAAPSPPAAPAPAAPA--------AAPPPP 273
P P P ++ P ++A +P PSP P A P
Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQ 2740
Query: 274 PPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGA 333
PP P L + PG V Q G ++ P + + P S + G
Sbjct: 2741 PPGPKVLRKLPGRLVTVVEEKELV-RRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGP 2799
Query: 334 AAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP----AAV 389
++ P G +AAP ++ P + +G T G+ + A+
Sbjct: 2800 ESSPPIGG--------PCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAI 2851
Query: 390 PPPA-------PGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTP-------TVLAPR 435
PPA P P A V ++ S T T+G P VL P+
Sbjct: 2852 TPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQ 2911
Query: 436 L---PQP--PQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAP 490
L PQP PQ P + N L P R + +P +++ +T P
Sbjct: 2912 LIPGPQPLGPQ-PVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPP 2970
Query: 491 RPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQL 550
P+ T PP+ + T +A VT TI +T P R P P
Sbjct: 2971 HPSPLTPLPPLLVCP-----TATVANTVTTVTI--------STSPPKRKRGRPPKNPPSP 3017
Query: 551 VLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSG 610
T+ G +R P S ++ + + ++L + G
Sbjct: 3018 RPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRL--ARLRLEAEG 3075
Query: 611 KQSTETAAN-VKELVQNLLD------GKIEAEDFTSRLYRELNSS---PQPYLVPFLKRS 660
+ ++ + V ++Q+ LD G +E L +L S+ P + P
Sbjct: 3076 MRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEK 3135
Query: 661 LPALRQLTP--DSAAFIQQSQQQPPPP 685
LP R P S ++ + QPP P
Sbjct: 3136 LPRKRAGAPVGGSPGLAKRGRLQPPSP 3162
Score = 43.9 bits (102), Expect = 8e-04
Identities = 99/437 (22%), Positives = 132/437 (30%), Gaps = 87/437 (19%)
Query: 20 KVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAA----GALGNHVVSGSPAGAAGAGP 75
KV+ L G L + L R + R AA+ G GSP+ + +GP
Sbjct: 2745 KVLRKLPGRL-----VTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGP 2799
Query: 76 AA------PAEGAPGAA----PEPPPAGRAR-----PGGGGPQRPG-------PPSPRRP 113
+ P E AP ++ P+ P R GGG P+ PP+ +R
Sbjct: 2800 ESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKR- 2858
Query: 114 LVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG 173
PP P G AP G +P P L + PG
Sbjct: 2859 ---RRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPG 2915
Query: 174 PGP-GPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA 232
P P GP P P P +P P LP
Sbjct: 2916 PQPLGPQPVHRPNP-----------------------LLSPVEKRRRGRPPKARDLP--- 2949
Query: 233 APGTV-----------IQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLA 281
PGT+ Q PP P P P A A PP
Sbjct: 2950 IPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPP-KRKRG 3008
Query: 282 RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPG-------AA 334
RPP +P P + V + S G P G + S G A
Sbjct: 3009 RPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLAR 3068
Query: 335 AAAPAPGVKA-ESPKRVVQAAPPAAQTLAASGPAS---TAASMVIGPTMQGALPSPAAVP 390
A G++ +S +V A LA SGP T + + P ++ P ++
Sbjct: 3069 LRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSLV 3128
Query: 391 PPAPGTPTGLPKGAAGA 407
PP LP+ AGA
Sbjct: 3129 PPL--ETEKLPRKRAGA 3143
Score = 31.2 bits (69), Expect = 5.6
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 5/86 (5%)
Query: 33 LAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPG-----AAP 87
L +AA LAP + + A+ A +L +P ++ P + P
Sbjct: 1798 LGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGP 1857
Query: 88 EPPPAGRARPGGGGPQRPGPPSPRRP 113
PP+ GG P+R PP PR P
Sbjct: 1858 PSPPSTATSFGGPRPRRQPPPPPRSP 1883
Score = 30.8 bits (68), Expect = 7.3
Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 15/144 (10%)
Query: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102
LAP P A+ G H ++ +PA ++ A APA P P P
Sbjct: 1748 LAPAPPLAPASPVGPAPAHTLTLAPA-SSSASLLAPA-SVQTLTLSPAPVPTLGPAAAQT 1805
Query: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV----PAAAAVAAGPEPAPAGPA 158
P S + P A +A P + S PV P + +GP
Sbjct: 1806 LALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGP-------- 1857
Query: 159 KPAGPAALAARAGPGPGPGPGPGP 182
P+ P+ + GP P P P P
Sbjct: 1858 -PSPPSTATSFGGPRPRRQPPPPP 1880
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 103 bits (258), Expect = 7e-22
Identities = 123/467 (26%), Positives = 155/467 (33%), Gaps = 73/467 (15%)
Query: 83 PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV-- 140
P +P+P P P PP P P P P PP L SAGS AP+
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPP-PPPPPPPPPPPLPSQSAPSAGSAAPMFV 665
Query: 141 ------------PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188
+ A+ P P P ++ P L G P P P P P P PG
Sbjct: 666 KYSTITRLQNASQHSGALFKPPTP-PVMQSQSVKPQILVPPNGVVPPPPPPPPP-PTPGS 723
Query: 189 --------PAGPGAAQTLNGSAALLNSH---HAAAPAVSLVNNGPAALLPLPKPAAPGTV 237
P P Q + L H H A P PLP A P +
Sbjct: 724 AMAQLKPAPCAPSLPQ-FSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPL 782
Query: 238 IQTP---------PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP- 287
+ P P V AAPP P P PPA PA PA+ PP PP P PP P
Sbjct: 783 VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPK 842
Query: 288 ----AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343
P +P P P+ + S P PA +P P A P VK
Sbjct: 843 QQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM---ESQPLKPVPANVAPQSPPAVK 899
Query: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKG 403
A+ PK + P + P S S+V P PSP PPP P PT
Sbjct: 900 AK-PKWQPSSIPVPSPDFPPPPPES---SLVFPPPP----PSPVPAPPPPP-PPTA---- 946
Query: 404 AAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENG 463
+PT SG T +P +PP P + + G +
Sbjct: 947 -----------SPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRP 995
Query: 464 QLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPG 510
+ + + ++ P P PA P + +S V PG
Sbjct: 996 SVDSLVSKFTPPAES---GSPSKETLPPPAAPPKPGKLNLSGVNLPG 1039
Score = 93.6 bits (231), Expect = 9e-19
Identities = 141/573 (24%), Positives = 196/573 (34%), Gaps = 101/573 (17%)
Query: 67 PAGAAGAGPAAPAEGAPGAAP---EPPPAGRARPGGGGPQRP------------GPPSPR 111
P G P P PG+A +P P + P P P PP+P
Sbjct: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764
Query: 112 RPLVPAGPAPPAAKLRP----PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALA 167
P P PP A +P P S + APV AA P P +PA PA+
Sbjct: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824
Query: 168 ARAGPGPGPGPGPGPGPGPGKPAG--------PGAAQTLNGSAALLNSHHAAAPAVSLVN 219
+ P P P P P P P P + + S P +
Sbjct: 825 PPSPPTP-----PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879
Query: 220 NGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAA---PSPPAAPAPAAPAAAPPPPPPA 276
+ P L P+P AP Q+PP V A P++ PSP P P + PPPPP+
Sbjct: 880 SQP--LKPVPANVAP----QSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPS 933
Query: 277 PATLARPPGHPAGPPTAAPAVPP-PAAAQNGGSAGAAPAPAP--------AAGGPAGVSG 327
P PP P PT + P ++ G P P P ++G
Sbjct: 934 PVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPK 993
Query: 328 QPGPGAAAAAPAPGVKAESPKRVV---QAAPPAAQTLAASGP----------ASTAASMV 374
+P + + P ++ SP + AAPP L SG S A ++
Sbjct: 994 RPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053
Query: 375 IGPTMQGAL-----PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTP 429
G + PS + PPP P T LP AV + TS A + P
Sbjct: 1054 SGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVF-------SGNTSPKVAVVNP 1106
Query: 430 TVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMA 489
PQ + + + PP R+++ +L QA Q TMA
Sbjct: 1107 ---------QPQQWSKMSVKKAPPPTRPKRNDSTRL------------TQAEISEQPTMA 1145
Query: 490 P-RPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIK--QVSQAQTTVQPSATLQRSPGV 546
P PTS P +VQ + R + +I + +S + +P+AT+
Sbjct: 1146 TVVPQVPTS--PKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALP 1203
Query: 547 QPQLVLGGAAQTASLGTATAVQTGTPQRTVPGA 579
P L Q A G + T +R P A
Sbjct: 1204 PPPPELLSDQQKAGYGGSHISGYATLRRGPPPA 1236
Score = 79.7 bits (195), Expect = 1e-14
Identities = 111/459 (24%), Positives = 148/459 (32%), Gaps = 116/459 (25%)
Query: 228 LPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP 287
L P +P I TP +PP P P PP P P PPPPPP P+ A G
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPPPPPP----PPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 288 A------------------GPPTAAPAVPPPAAAQ----------NGGSAGAAPAPAPAA 319
A P PP +Q NG P P P
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 320 GGPAGVSGQPGPGAAA----AAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVI 375
G A +P P A + +AP P +K + + Q AP
Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP-------------------- 760
Query: 376 GPTMQGALPSPAAVPPPAPGTP-TGLP-----KGAAGAVTQSLSRTPTATTSGIR----- 424
PT P PA +PP AP P +P K A VTQ+ TPT +
Sbjct: 761 -PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819
Query: 425 --ATLTPTVLAPRLPQPPQNPTNIQNF---------------------QLPPGMVLVRSE 461
+ + P+ P +P PP Q+F Q PP E
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879
Query: 462 NGQLLMIPQQALAQ----MQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQ 517
+ L +P Q ++A+ QP + P P P P + P +P+ A
Sbjct: 880 SQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPP 939
Query: 518 VTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVP 577
P T P+ SPG + ++T+S G TPQR
Sbjct: 940 PPP----------PPTASPTPDKSGSPGKK-------TSKTSSPGGKK--PPPTPQRN-- 978
Query: 578 GATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTET 616
+ +SS A + +S A SG S ET
Sbjct: 979 SSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKET 1017
Score = 31.6 bits (70), Expect = 4.3
Identities = 26/80 (32%), Positives = 30/80 (37%), Gaps = 11/80 (13%)
Query: 738 PTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQ----------LNP 787
P PL Q PPKP I P T T P+V P P + Q P
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP 829
Query: 788 LQPVPVVKPAVLPGTKALSA 807
PVP V P LP ++ A
Sbjct: 830 TPPVP-VPPPTLPKQQSFCA 848
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 103 bits (257), Expect = 9e-22
Identities = 120/437 (27%), Positives = 148/437 (33%), Gaps = 71/437 (16%)
Query: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125
+P G G +G PG P P GRA P G P PGPP P+ P GPA PA +
Sbjct: 743 TPGGRVKEGGLKGQKGEPGV---PGPPGRAGPPGS-PCLPGPPGLPCPVSPLGPAGPALQ 798
Query: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG-PG--------- 175
P P+G G P G + P P + P + PG PG
Sbjct: 799 TVPGPQGPPG-----PPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKG 853
Query: 176 -PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234
PG G PGP P GP + ++ + GP P P
Sbjct: 854 DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGV 913
Query: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP-PPPPAPATLARPPGH------- 286
+ P G + P P P P P P PP P PPG
Sbjct: 914 PGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 973
Query: 287 -PAGPP--TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343
AG P + P PA A+ G +G A AP PA GP G G PGP P PG+
Sbjct: 974 GEAGAPGHKGSKGAPGPAGAR--GESGLAGAPGPA--GPPGPPGPPGP------PGPGLP 1023
Query: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP----------A 393
A P + +A GP P + G P P
Sbjct: 1024 AGFDDMEGSGGPFWSTARSADGPQGP-------PGLPGLKGDPGVPGLPGAKGEVGADGV 1076
Query: 394 PGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPP 453
PG P GLP G G + + V P LP PP PP
Sbjct: 1077 PGFP-GLP-GREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPG----------PP 1124
Query: 454 G-MVLVRSENGQLLMIP 469
G +V V ++G +L +P
Sbjct: 1125 GPVVYVSEQDGSVLSVP 1141
Score = 77.4 bits (189), Expect = 7e-14
Identities = 108/378 (28%), Positives = 122/378 (32%), Gaps = 65/378 (17%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
P G G P P ++ P PAG G P R GPP P +P P PP +
Sbjct: 910 PPGVPGL-PGEPGRFGVNSSDVPGPAGLP----GVPGREGPPG--FPGLPGPPGPPGREG 962
Query: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186
P G GS A + P PAG +G A AGP PGP PGP
Sbjct: 963 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG--PPGP 1020
Query: 187 GKPAGPGAAQTLNG---SAALLNSHHAAAPAVSLVNNGPAAL-LPLPK--------PAAP 234
G PAG + G S A P + + P LP K P P
Sbjct: 1021 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 1080
Query: 235 GTVIQTPPFVGAAAPPAP-------AAPSPPAAPAPAAPAAAPPPPPPAP--------AT 279
G P G A P P P P PP PP P +
Sbjct: 1081 G----LPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGS 1136
Query: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP---------------AAGGPA- 323
+ PG P G P A P N GS G +P P A GPA
Sbjct: 1137 VLSVPG-PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 1195
Query: 324 -GVSGQPG-PGAAAAAPAPGVKAE--SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTM 379
G G+PG G PG K E P R P L AS+ G
Sbjct: 1196 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGR---PGRPGMNGLKGEKGEPGDASLGFGMRG 1252
Query: 380 QGALPSPAAVPPPAPGTP 397
P P PP PGTP
Sbjct: 1253 MPGPPGPPG-PPGPPGTP 1269
Score = 75.9 bits (185), Expect = 2e-13
Identities = 109/411 (26%), Positives = 131/411 (31%), Gaps = 110/411 (26%)
Query: 54 AAGALGNHVVSGSPA--GAAG-AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSP 110
A G +G V G P G G AGP P +G G+ E G+ G G P PGPP P
Sbjct: 1067 AKGEVGADGVPGFPGLPGREGIAGPQGP-KGDRGSRGEKGDPGK--DGVGQPGLPGPPGP 1123
Query: 111 RRPLVPAGPAPPAAKLRPPPEGSAGSCA-PVPAAAAVAAGPE-----PAPAGP-AKPA-- 161
P+V + P PEG G P PA G + P P G +P
Sbjct: 1124 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 1183
Query: 162 --------GPAALAARAGPGPGPGPGPGPGPG-------PGKPAGPGAAQTLNGSAALLN 206
GPA A+ PG PGP PG PG+P PG +NG
Sbjct: 1184 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG----MNGLKGEKG 1239
Query: 207 SHHAAAPAVSLVNNGPAALLPLPKPAAPGT-VIQTPPFVGAAAPPAPAAPSPPAAPAP-A 264
A+ + P P P PGT V + F ++ P P P P P
Sbjct: 1240 EPGDASLGFGM-RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKG 1298
Query: 265 APAAAPPPPPPAP--------------------------------------ATLARPPGH 286
A PP PP ++L PPG
Sbjct: 1299 AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP 1358
Query: 287 PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA-PGVKAE 345
P P P +P P G G P G G G PGP P+ PG
Sbjct: 1359 PG--PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPG---- 1412
Query: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396
P QT++ GP P P PP PGT
Sbjct: 1413 ----------PHRQTISVPGP-----------------PGPPG-PPGPPGT 1435
Score = 72.0 bits (175), Expect = 3e-12
Identities = 124/468 (26%), Positives = 138/468 (29%), Gaps = 91/468 (19%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP 107
P R G+LG G GPA A G G A P PAG PG GP PGP
Sbjct: 963 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAG-ARGESGLAGAPGPAGP--PGPPGP--PGP 1017
Query: 108 PSPRRPL--------------------VPAG-PAPPAAKLRPPPEGSAGSCAPVPAAAAV 146
P P P P G P P K P G G+ V A
Sbjct: 1018 PGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 1077
Query: 147 AAGPEPAPAGPAKPAGPAALAARAGPGPGPG-PGPG-PG-PGPGKPAGP--------GAA 195
P G A P GP G PG G G PG PGP P GP G+
Sbjct: 1078 GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSV 1137
Query: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP----AAPGTVIQTPPFVGAAAPPA 251
++ G PA N G P P PG++ P GA P
Sbjct: 1138 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS--PDGGALGPAQ 1195
Query: 252 PAAPSPPAAPAPAAPAAAP----------PPPPPAPATLARPPGHPA------------G 289
A P P P P P P L G P G
Sbjct: 1196 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 1255
Query: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP-GAAAAAPAPGVKAESPK 348
PP P P P S A + P G G G PGP GA PG + P
Sbjct: 1256 PP-GPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 1314
Query: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAV 408
+Q G A G G + PP P P G P G G
Sbjct: 1315 DFLQLEAEMKGEKGDRGDAGQKGER--GEPGGGGFFGSSLPGPPGPPGPRGYP-GIPGPK 1371
Query: 409 TQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNI--QNFQLPPG 454
+S+ P P PQ P I + Q PPG
Sbjct: 1372 GESIRGQPG-------------------PPGPQGPPGIGYEGRQGPPG 1400
Score = 65.1 bits (157), Expect = 3e-10
Identities = 90/321 (28%), Positives = 108/321 (33%), Gaps = 55/321 (17%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPA--EGAPGA--APEPPPAGRARPGGGG-P 102
PE R AG G G+ G P +G PG+ +P+ G A+ G G P
Sbjct: 1143 PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 1202
Query: 103 QRPGPPSPR-RPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE--PAPAGPAK 159
GPP P RP P RP G G P A++ G P P GP
Sbjct: 1203 GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGE-PGDASLGFGMRGMPGPPGPPG 1261
Query: 160 PAGPA----------ALAARAGPGPGPGPGPGPGP-------GPGKPAGPGAAQTLNGSA 202
P GP A ++R GP PG PGP GP P G L A
Sbjct: 1262 PPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEA 1321
Query: 203 ALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP---PA 259
+ A G +P G F G++ P P P P P
Sbjct: 1322 EMKGEKGDRGDAGQKGERG--------EPGGGG-------FFGSSLPGPPGPPGPRGYPG 1366
Query: 260 APAPAAPAAAPPPPPPAPATLARPPG----HPAGPPTAAPAVPPPAAAQNGGSAGAAPAP 315
P P + P PP P PPG GPP P PP + G P
Sbjct: 1367 IPGPKGESIRGQPGPPGPQG---PPGIGYEGRQGPP--GPPGPPGPPSFPGPHRQTISVP 1421
Query: 316 APAAGGPAGVSGQPGPGAAAA 336
P GP G G PG A++
Sbjct: 1422 GPP--GPPGPPGPPGTMGASS 1440
Score = 60.8 bits (146), Expect = 7e-09
Identities = 95/335 (28%), Positives = 112/335 (33%), Gaps = 77/335 (22%)
Query: 51 RAAAAGALGNHVVSGSPAGAAG-AGPAAPAEGAP-----------GAAPEPPPAG----R 94
R G GN G P GA G GP P P G + AG R
Sbjct: 1281 RPGPPGLPGNQGPPG-PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER 1339
Query: 95 ARPGGGG------PQRPGPPSPRR-PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVA 147
PGGGG P PGPP PR P +P GP + + +P P G G +
Sbjct: 1340 GEPGGGGFFGSSLPGPPGPPGPRGYPGIP-GPKGESIRGQPGPPGPQGP-------PGIG 1391
Query: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPG------PGPGPGPGPGKPAGPGAAQTLNG- 200
P GP P GP + PGP PGP PGP PG P PG +G
Sbjct: 1392 YEGRQGPPGPPGPPGPPSF-------PGPHRQTISVPGP-PGP-PGPPGPPGTMGASSGV 1442
Query: 201 -----SAALLNSHHAAAPAVSL-----------VNNG-----PAALLPLPKPAAPGTVIQ 239
A+L H + V NG A PLP+
Sbjct: 1443 RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAAL 1502
Query: 240 TPPFV---GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA 296
PP V + P P P A P A A PP P P P H + PA
Sbjct: 1503 QPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSSYVHLRPA 1561
Query: 297 VP--PPAAAQNGGS--AGAAPAPAPAAGGPAGVSG 327
P PPA + +P +GG G+ G
Sbjct: 1562 RPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRG 1596
Score = 52.8 bits (125), Expect = 2e-06
Identities = 99/415 (23%), Positives = 135/415 (32%), Gaps = 76/415 (18%)
Query: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALA 167
P P+ PL P P P GS EPA A P P P+ L
Sbjct: 46 PEPQGPL-PVQPTADTTTHVTPRNGST----------------EPATA-PGSPEPPSELL 87
Query: 168 ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP 227
P P G G + + + P SL L
Sbjct: 88 EDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLET 147
Query: 228 LPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP 287
P A TP G P+ PS P A A P P P+P +L RP
Sbjct: 148 PVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHT--TEAGTLPAPTPSPPSLGRP---- 201
Query: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP-GPGAAAAAPAPGVKAES 346
P P+VPPP++ + S+ AP P G P G + AA AP + +
Sbjct: 202 -WAPLTGPSVPPPSSGRASLSSLLGGAP------PWGSLQDPDSQGLSPAAAAPSQQLQR 254
Query: 347 PKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAG 406
P V+ P ++ P + G+L AA + G P L + A
Sbjct: 255 PD--VRLRTP-----------------LLHPLVMGSLGKHAAPSAFSSGLPGALSQVAVT 295
Query: 407 AVTQS----LSRTPTATTSGI---RATLTPTVLAPR---LPQPPQNPT----NIQNFQLP 452
+T+ +S + G+ A L AP LP PP P I F LP
Sbjct: 296 TLTRDSGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPVCGHLGISRFWLP 355
Query: 453 PGMVLVRSENGQLLMIPQQALAQMQAQAHAQP-------QTTMAPRPATPTSAPP 500
+ E+G+ + +A + Q H P + P + P APP
Sbjct: 356 NHL---HHESGEQVRAGARAWGGL-LQTHCHPFLAWFFCLLLVPPCGSVPPPAPP 406
Score = 40.0 bits (92), Expect = 0.012
Identities = 57/215 (26%), Positives = 70/215 (32%), Gaps = 19/215 (8%)
Query: 36 SAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAP------AEGAPGAAPEP 89
S A L TP A AG +G+ + P++P A P P P
Sbjct: 136 SLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSP 195
Query: 90 PPAGRARPGGGGPQRPGPPSPRRPLVP-AGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAA 148
P GR GP P P S R L G APP L+ P A P+
Sbjct: 196 PSLGRPWAPLTGPSVPPPSSGRASLSSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQ--LQ 253
Query: 149 GPEPAPAGP-AKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
P+ P P +L A P PG A TL + S
Sbjct: 254 RPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPG-------ALSQVAVTTLTRDSGAWVS 306
Query: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242
H A + L NN +ALL A G + PP
Sbjct: 307 HVANSVGPGLANN--SALLGADPEAPAGRCLPLPP 339
Score = 34.3 bits (77), Expect = 0.66
Identities = 29/101 (28%), Positives = 37/101 (36%), Gaps = 17/101 (16%)
Query: 46 RTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRP 105
RTP + G+LG H A P+A + G PGA + R G
Sbjct: 260 RTPLLHPLVMGSLGKH-----------AAPSAFSSGLPGALSQVAVTTLTRDSGAWVSHV 308
Query: 106 GPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV 146
V G A +A L PE AG C P+P + V
Sbjct: 309 ANS------VGPGLANNSALLGADPEAPAGRCLPLPPSLPV 343
>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
sapiens]
Length = 1336
Score = 103 bits (257), Expect = 9e-22
Identities = 120/437 (27%), Positives = 148/437 (33%), Gaps = 71/437 (16%)
Query: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125
+P G G +G PG P P GRA P G P PGPP P+ P GPA PA +
Sbjct: 328 TPGGRVKEGGLKGQKGEPGV---PGPPGRAGPPGS-PCLPGPPGLPCPVSPLGPAGPALQ 383
Query: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG-PG--------- 175
P P+G G P G + P P + P + PG PG
Sbjct: 384 TVPGPQGPPG-----PPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKG 438
Query: 176 -PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234
PG G PGP P GP + ++ + GP P P
Sbjct: 439 DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGV 498
Query: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP-PPPPAPATLARPPGH------- 286
+ P G + P P P P P P PP P PPG
Sbjct: 499 PGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 558
Query: 287 -PAGPP--TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343
AG P + P PA A+ G +G A AP PA GP G G PGP P PG+
Sbjct: 559 GEAGAPGHKGSKGAPGPAGAR--GESGLAGAPGPA--GPPGPPGPPGP------PGPGLP 608
Query: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP----------A 393
A P + +A GP P + G P P
Sbjct: 609 AGFDDMEGSGGPFWSTARSADGPQGP-------PGLPGLKGDPGVPGLPGAKGEVGADGV 661
Query: 394 PGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPP 453
PG P GLP G G + + V P LP PP PP
Sbjct: 662 PGFP-GLP-GREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPG----------PP 709
Query: 454 G-MVLVRSENGQLLMIP 469
G +V V ++G +L +P
Sbjct: 710 GPVVYVSEQDGSVLSVP 726
Score = 77.4 bits (189), Expect = 7e-14
Identities = 108/378 (28%), Positives = 122/378 (32%), Gaps = 65/378 (17%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
P G G P P ++ P PAG G P R GPP P +P P PP +
Sbjct: 495 PPGVPGL-PGEPGRFGVNSSDVPGPAGLP----GVPGREGPPG--FPGLPGPPGPPGREG 547
Query: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186
P G GS A + P PAG +G A AGP PGP PGP
Sbjct: 548 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG--PPGP 605
Query: 187 GKPAGPGAAQTLNG---SAALLNSHHAAAPAVSLVNNGPAAL-LPLPK--------PAAP 234
G PAG + G S A P + + P LP K P P
Sbjct: 606 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 665
Query: 235 GTVIQTPPFVGAAAPPAP-------AAPSPPAAPAPAAPAAAPPPPPPAP--------AT 279
G P G A P P P P PP PP P +
Sbjct: 666 G----LPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGS 721
Query: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP---------------AAGGPA- 323
+ PG P G P A P N GS G +P P A GPA
Sbjct: 722 VLSVPG-PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 780
Query: 324 -GVSGQPG-PGAAAAAPAPGVKAE--SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTM 379
G G+PG G PG K E P R P L AS+ G
Sbjct: 781 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGR---PGRPGMNGLKGEKGEPGDASLGFGMRG 837
Query: 380 QGALPSPAAVPPPAPGTP 397
P P PP PGTP
Sbjct: 838 MPGPPGPPG-PPGPPGTP 854
Score = 75.9 bits (185), Expect = 2e-13
Identities = 109/411 (26%), Positives = 131/411 (31%), Gaps = 110/411 (26%)
Query: 54 AAGALGNHVVSGSPA--GAAG-AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSP 110
A G +G V G P G G AGP P +G G+ E G+ G G P PGPP P
Sbjct: 652 AKGEVGADGVPGFPGLPGREGIAGPQGP-KGDRGSRGEKGDPGK--DGVGQPGLPGPPGP 708
Query: 111 RRPLVPAGPAPPAAKLRPPPEGSAGSCA-PVPAAAAVAAGPE-----PAPAGP-AKPA-- 161
P+V + P PEG G P PA G + P P G +P
Sbjct: 709 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 768
Query: 162 --------GPAALAARAGPGPGPGPGPGPGPG-------PGKPAGPGAAQTLNGSAALLN 206
GPA A+ PG PGP PG PG+P PG +NG
Sbjct: 769 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG----MNGLKGEKG 824
Query: 207 SHHAAAPAVSLVNNGPAALLPLPKPAAPGT-VIQTPPFVGAAAPPAPAAPSPPAAPAP-A 264
A+ + P P P PGT V + F ++ P P P P P
Sbjct: 825 EPGDASLGFGM-RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKG 883
Query: 265 APAAAPPPPPPAP--------------------------------------ATLARPPGH 286
A PP PP ++L PPG
Sbjct: 884 AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP 943
Query: 287 PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA-PGVKAE 345
P P P +P P G G P G G G PGP P+ PG
Sbjct: 944 PG--PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPG---- 997
Query: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396
P QT++ GP P P PP PGT
Sbjct: 998 ----------PHRQTISVPGP-----------------PGPPG-PPGPPGT 1020
Score = 72.0 bits (175), Expect = 3e-12
Identities = 124/468 (26%), Positives = 138/468 (29%), Gaps = 91/468 (19%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP 107
P R G+LG G GPA A G G A P PAG PG GP PGP
Sbjct: 548 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAG-ARGESGLAGAPGPAGP--PGPPGP--PGP 602
Query: 108 PSPRRPL--------------------VPAG-PAPPAAKLRPPPEGSAGSCAPVPAAAAV 146
P P P P G P P K P G G+ V A
Sbjct: 603 PGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 662
Query: 147 AAGPEPAPAGPAKPAGPAALAARAGPGPGPG-PGPG-PG-PGPGKPAGP--------GAA 195
P G A P GP G PG G G PG PGP P GP G+
Sbjct: 663 GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSV 722
Query: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP----AAPGTVIQTPPFVGAAAPPA 251
++ G PA N G P P PG++ P GA P
Sbjct: 723 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS--PDGGALGPAQ 780
Query: 252 PAAPSPPAAPAPAAPAAAP----------PPPPPAPATLARPPGHPA------------G 289
A P P P P P P L G P G
Sbjct: 781 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 840
Query: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP-GAAAAAPAPGVKAESPK 348
PP P P P S A + P G G G PGP GA PG + P
Sbjct: 841 PP-GPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 899
Query: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAV 408
+Q G A G G + PP P P G P G G
Sbjct: 900 DFLQLEAEMKGEKGDRGDAGQKGER--GEPGGGGFFGSSLPGPPGPPGPRGYP-GIPGPK 956
Query: 409 TQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNI--QNFQLPPG 454
+S+ P P PQ P I + Q PPG
Sbjct: 957 GESIRGQPG-------------------PPGPQGPPGIGYEGRQGPPG 985
Score = 65.1 bits (157), Expect = 3e-10
Identities = 90/321 (28%), Positives = 108/321 (33%), Gaps = 55/321 (17%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPA--EGAPGA--APEPPPAGRARPGGGG-P 102
PE R AG G G+ G P +G PG+ +P+ G A+ G G P
Sbjct: 728 PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 787
Query: 103 QRPGPPSPR-RPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE--PAPAGPAK 159
GPP P RP P RP G G P A++ G P P GP
Sbjct: 788 GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGE-PGDASLGFGMRGMPGPPGPPG 846
Query: 160 PAGPA----------ALAARAGPGPGPGPGPGPGP-------GPGKPAGPGAAQTLNGSA 202
P GP A ++R GP PG PGP GP P G L A
Sbjct: 847 PPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEA 906
Query: 203 ALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP---PA 259
+ A G +P G F G++ P P P P P
Sbjct: 907 EMKGEKGDRGDAGQKGERG--------EPGGGG-------FFGSSLPGPPGPPGPRGYPG 951
Query: 260 APAPAAPAAAPPPPPPAPATLARPPG----HPAGPPTAAPAVPPPAAAQNGGSAGAAPAP 315
P P + P PP P PPG GPP P PP + G P
Sbjct: 952 IPGPKGESIRGQPGPPGPQG---PPGIGYEGRQGPP--GPPGPPGPPSFPGPHRQTISVP 1006
Query: 316 APAAGGPAGVSGQPGPGAAAA 336
P GP G G PG A++
Sbjct: 1007 GPP--GPPGPPGPPGTMGASS 1025
Score = 60.8 bits (146), Expect = 7e-09
Identities = 95/335 (28%), Positives = 112/335 (33%), Gaps = 77/335 (22%)
Query: 51 RAAAAGALGNHVVSGSPAGAAG-AGPAAPAEGAP-----------GAAPEPPPAG----R 94
R G GN G P GA G GP P P G + AG R
Sbjct: 866 RPGPPGLPGNQGPPG-PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER 924
Query: 95 ARPGGGG------PQRPGPPSPRR-PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVA 147
PGGGG P PGPP PR P +P GP + + +P P G G +
Sbjct: 925 GEPGGGGFFGSSLPGPPGPPGPRGYPGIP-GPKGESIRGQPGPPGPQGP-------PGIG 976
Query: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPG------PGPGPGPGPGKPAGPGAAQTLNG- 200
P GP P GP + PGP PGP PGP PG P PG +G
Sbjct: 977 YEGRQGPPGPPGPPGPPSF-------PGPHRQTISVPGP-PGP-PGPPGPPGTMGASSGV 1027
Query: 201 -----SAALLNSHHAAAPAVSL-----------VNNG-----PAALLPLPKPAAPGTVIQ 239
A+L H + V NG A PLP+
Sbjct: 1028 RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAAL 1087
Query: 240 TPPFV---GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA 296
PP V + P P P A P A A PP P P P H + PA
Sbjct: 1088 QPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSSYVHLRPA 1146
Query: 297 VP--PPAAAQNGGS--AGAAPAPAPAAGGPAGVSG 327
P PPA + +P +GG G+ G
Sbjct: 1147 RPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRG 1181
>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
sapiens]
Length = 1516
Score = 103 bits (257), Expect = 9e-22
Identities = 120/437 (27%), Positives = 148/437 (33%), Gaps = 71/437 (16%)
Query: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125
+P G G +G PG P P GRA P G P PGPP P+ P GPA PA +
Sbjct: 508 TPGGRVKEGGLKGQKGEPGV---PGPPGRAGPPGS-PCLPGPPGLPCPVSPLGPAGPALQ 563
Query: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG-PG--------- 175
P P+G G P G + P P + P + PG PG
Sbjct: 564 TVPGPQGPPG-----PPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKG 618
Query: 176 -PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234
PG G PGP P GP + ++ + GP P P
Sbjct: 619 DPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGV 678
Query: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP-PPPPAPATLARPPGH------- 286
+ P G + P P P P P P PP P PPG
Sbjct: 679 PGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSL 738
Query: 287 -PAGPP--TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343
AG P + P PA A+ G +G A AP PA GP G G PGP P PG+
Sbjct: 739 GEAGAPGHKGSKGAPGPAGAR--GESGLAGAPGPA--GPPGPPGPPGP------PGPGLP 788
Query: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP----------A 393
A P + +A GP P + G P P
Sbjct: 789 AGFDDMEGSGGPFWSTARSADGPQGP-------PGLPGLKGDPGVPGLPGAKGEVGADGV 841
Query: 394 PGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPP 453
PG P GLP G G + + V P LP PP PP
Sbjct: 842 PGFP-GLP-GREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPG----------PP 889
Query: 454 G-MVLVRSENGQLLMIP 469
G +V V ++G +L +P
Sbjct: 890 GPVVYVSEQDGSVLSVP 906
Score = 77.4 bits (189), Expect = 7e-14
Identities = 108/378 (28%), Positives = 122/378 (32%), Gaps = 65/378 (17%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
P G G P P ++ P PAG G P R GPP P +P P PP +
Sbjct: 675 PPGVPGL-PGEPGRFGVNSSDVPGPAGLP----GVPGREGPPG--FPGLPGPPGPPGREG 727
Query: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186
P G GS A + P PAG +G A AGP PGP PGP
Sbjct: 728 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG--PPGP 785
Query: 187 GKPAGPGAAQTLNG---SAALLNSHHAAAPAVSLVNNGPAAL-LPLPK--------PAAP 234
G PAG + G S A P + + P LP K P P
Sbjct: 786 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 845
Query: 235 GTVIQTPPFVGAAAPPAP-------AAPSPPAAPAPAAPAAAPPPPPPAP--------AT 279
G P G A P P P P PP PP P +
Sbjct: 846 G----LPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGS 901
Query: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP---------------AAGGPA- 323
+ PG P G P A P N GS G +P P A GPA
Sbjct: 902 VLSVPG-PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ 960
Query: 324 -GVSGQPG-PGAAAAAPAPGVKAE--SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTM 379
G G+PG G PG K E P R P L AS+ G
Sbjct: 961 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGR---PGRPGMNGLKGEKGEPGDASLGFGMRG 1017
Query: 380 QGALPSPAAVPPPAPGTP 397
P P PP PGTP
Sbjct: 1018 MPGPPGPPG-PPGPPGTP 1034
Score = 75.9 bits (185), Expect = 2e-13
Identities = 109/411 (26%), Positives = 131/411 (31%), Gaps = 110/411 (26%)
Query: 54 AAGALGNHVVSGSPA--GAAG-AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSP 110
A G +G V G P G G AGP P +G G+ E G+ G G P PGPP P
Sbjct: 832 AKGEVGADGVPGFPGLPGREGIAGPQGP-KGDRGSRGEKGDPGK--DGVGQPGLPGPPGP 888
Query: 111 RRPLVPAGPAPPAAKLRPPPEGSAGSCA-PVPAAAAVAAGPE-----PAPAGP-AKPA-- 161
P+V + P PEG G P PA G + P P G +P
Sbjct: 889 PGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSI 948
Query: 162 --------GPAALAARAGPGPGPGPGPGPGPG-------PGKPAGPGAAQTLNGSAALLN 206
GPA A+ PG PGP PG PG+P PG +NG
Sbjct: 949 FSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPG----MNGLKGEKG 1004
Query: 207 SHHAAAPAVSLVNNGPAALLPLPKPAAPGT-VIQTPPFVGAAAPPAPAAPSPPAAPAP-A 264
A+ + P P P PGT V + F ++ P P P P P
Sbjct: 1005 EPGDASLGFGM-RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKG 1063
Query: 265 APAAAPPPPPPAP--------------------------------------ATLARPPGH 286
A PP PP ++L PPG
Sbjct: 1064 AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGP 1123
Query: 287 PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA-PGVKAE 345
P P P +P P G G P G G G PGP P+ PG
Sbjct: 1124 PG--PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPG---- 1177
Query: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396
P QT++ GP P P PP PGT
Sbjct: 1178 ----------PHRQTISVPGP-----------------PGPPG-PPGPPGT 1200
Score = 72.0 bits (175), Expect = 3e-12
Identities = 124/468 (26%), Positives = 138/468 (29%), Gaps = 91/468 (19%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP 107
P R G+LG G GPA A G G A P PAG PG GP PGP
Sbjct: 728 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAG-ARGESGLAGAPGPAGP--PGPPGP--PGP 782
Query: 108 PSPRRPL--------------------VPAG-PAPPAAKLRPPPEGSAGSCAPVPAAAAV 146
P P P P G P P K P G G+ V A
Sbjct: 783 PGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVP 842
Query: 147 AAGPEPAPAGPAKPAGPAALAARAGPGPGPG-PGPG-PG-PGPGKPAGP--------GAA 195
P G A P GP G PG G G PG PGP P GP G+
Sbjct: 843 GFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSV 902
Query: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP----AAPGTVIQTPPFVGAAAPPA 251
++ G PA N G P P PG++ P GA P
Sbjct: 903 LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFS--PDGGALGPAQ 960
Query: 252 PAAPSPPAAPAPAAPAAAP----------PPPPPAPATLARPPGHPA------------G 289
A P P P P P P L G P G
Sbjct: 961 KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG 1020
Query: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP-GAAAAAPAPGVKAESPK 348
PP P P P S A + P G G G PGP GA PG + P
Sbjct: 1021 PP-GPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPF 1079
Query: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAV 408
+Q G A G G + PP P P G P G G
Sbjct: 1080 DFLQLEAEMKGEKGDRGDAGQKGER--GEPGGGGFFGSSLPGPPGPPGPRGYP-GIPGPK 1136
Query: 409 TQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNI--QNFQLPPG 454
+S+ P P PQ P I + Q PPG
Sbjct: 1137 GESIRGQPG-------------------PPGPQGPPGIGYEGRQGPPG 1165
Score = 65.1 bits (157), Expect = 3e-10
Identities = 90/321 (28%), Positives = 108/321 (33%), Gaps = 55/321 (17%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPA--EGAPGA--APEPPPAGRARPGGGG-P 102
PE R AG G G+ G P +G PG+ +P+ G A+ G G P
Sbjct: 908 PEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEP 967
Query: 103 QRPGPPSPR-RPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE--PAPAGPAK 159
GPP P RP P RP G G P A++ G P P GP
Sbjct: 968 GFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGE-PGDASLGFGMRGMPGPPGPPG 1026
Query: 160 PAGPA----------ALAARAGPGPGPGPGPGPGP-------GPGKPAGPGAAQTLNGSA 202
P GP A ++R GP PG PGP GP P G L A
Sbjct: 1027 PPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEA 1086
Query: 203 ALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP---PA 259
+ A G +P G F G++ P P P P P
Sbjct: 1087 EMKGEKGDRGDAGQKGERG--------EPGGGG-------FFGSSLPGPPGPPGPRGYPG 1131
Query: 260 APAPAAPAAAPPPPPPAPATLARPPG----HPAGPPTAAPAVPPPAAAQNGGSAGAAPAP 315
P P + P PP P PPG GPP P PP + G P
Sbjct: 1132 IPGPKGESIRGQPGPPGPQG---PPGIGYEGRQGPP--GPPGPPGPPSFPGPHRQTISVP 1186
Query: 316 APAAGGPAGVSGQPGPGAAAA 336
P GP G G PG A++
Sbjct: 1187 GPP--GPPGPPGPPGTMGASS 1205
Score = 60.8 bits (146), Expect = 7e-09
Identities = 95/335 (28%), Positives = 112/335 (33%), Gaps = 77/335 (22%)
Query: 51 RAAAAGALGNHVVSGSPAGAAG-AGPAAPAEGAP-----------GAAPEPPPAG----R 94
R G GN G P GA G GP P P G + AG R
Sbjct: 1046 RPGPPGLPGNQGPPG-PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGER 1104
Query: 95 ARPGGGG------PQRPGPPSPRR-PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVA 147
PGGGG P PGPP PR P +P GP + + +P P G G +
Sbjct: 1105 GEPGGGGFFGSSLPGPPGPPGPRGYPGIP-GPKGESIRGQPGPPGPQGP-------PGIG 1156
Query: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPG------PGPGPGPGPGKPAGPGAAQTLNG- 200
P GP P GP + PGP PGP PGP PG P PG +G
Sbjct: 1157 YEGRQGPPGPPGPPGPPSF-------PGPHRQTISVPGP-PGP-PGPPGPPGTMGASSGV 1207
Query: 201 -----SAALLNSHHAAAPAVSL-----------VNNG-----PAALLPLPKPAAPGTVIQ 239
A+L H + V NG A PLP+
Sbjct: 1208 RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAAL 1267
Query: 240 TPPFV---GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA 296
PP V + P P P A P A A PP P P P H + PA
Sbjct: 1268 QPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAP-HHSSYVHLRPA 1326
Query: 297 VP--PPAAAQNGGS--AGAAPAPAPAAGGPAGVSG 327
P PPA + +P +GG G+ G
Sbjct: 1327 RPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRG 1361
Score = 43.1 bits (100), Expect = 0.001
Identities = 50/203 (24%), Positives = 62/203 (30%), Gaps = 25/203 (12%)
Query: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALA 167
P P+ PL P P P GS EPA A P P P+ L
Sbjct: 46 PEPQGPL-PVQPTADTTTHVTPRNGST----------------EPATA-PGSPEPPSELL 87
Query: 168 ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP 227
P P G G + + + P SL L
Sbjct: 88 EDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLET 147
Query: 228 LPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP 287
P A TP G P+ PS P A A P P P+P +L RP
Sbjct: 148 PVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHT--TEAGTLPAPTPSPPSLGRP---- 201
Query: 288 AGPPTAAPAVPPPAAAQNGGSAG 310
P P+VPPP++ + G
Sbjct: 202 -WAPLTGPSVPPPSSERISEEVG 223
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 103 bits (256), Expect = 1e-21
Identities = 99/390 (25%), Positives = 120/390 (30%), Gaps = 53/390 (13%)
Query: 222 PAALLPLPKPAA----PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP--- 274
P P P P + P T +PP PP PSPP P P PP
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIST 1460
Query: 275 ---PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP 331
P P T PP PPT P+ P P P P P
Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTT--------TPPPTTTPSPPTTTPITP-- 1510
Query: 332 GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPP 391
A+ P SP PP T P+ + + PT LP P P
Sbjct: 1511 -PASTTTLPPTTTPSPPTTTTTTPPPTTT-----PSPPTTTPITPPTSTTTLP-PTTTPS 1563
Query: 392 PAPGTPTGLPKGAA-GAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQ 450
P P T T P T + PT TT+ T TP+ PP T
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT-----P 1618
Query: 451 LPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPG 510
PP + + P + P TT P T T +PP+ +T P
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPT 1678
Query: 511 T-----------PIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTA 559
T P TP+ S TT PS+T SP P + + T
Sbjct: 1679 TTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP---PPTTMTTPSPTT 1735
Query: 560 SLGTATAVQTGTPQRTVPGATTTSSAATET 589
+ T T P TTTSS T T
Sbjct: 1736 TPSPPTTTMTTLP------PTTTSSPLTTT 1759
Score = 100 bits (249), Expect = 7e-21
Identities = 92/368 (25%), Positives = 115/368 (31%), Gaps = 33/368 (8%)
Query: 233 APGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPT 292
+P T +PP P PSPP P P PP T PP PP
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTT-TTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 293 AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352
+ PPP P+P P+ + P P P SP
Sbjct: 1459 STTTTPPPTT-----------TPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507
Query: 353 AAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSL 412
PPA+ T P +T S PT P P P P TP P +
Sbjct: 1508 ITPPASTTTL---PPTTTPS---PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1561
Query: 413 SRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQ-- 470
P TT+ T TP+ P PP T P + P
Sbjct: 1562 PSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP 1621
Query: 471 --QALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGT-----PIIARQVTPTTI 523
+ + P TT +P P T T+ PP +T +P T P I TP
Sbjct: 1622 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP---TTTPSPPTTTTPSPPITTTTTPPPT 1678
Query: 524 IKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTP-QRTVPGATTT 582
S TT P T +P P T + ++T + P T P TTT
Sbjct: 1679 TTPSSPITTTPSPPTTTMTTP--SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTT 1736
Query: 583 SSAATETM 590
S T TM
Sbjct: 1737 PSPPTTTM 1744
Score = 99.0 bits (245), Expect = 2e-20
Identities = 93/392 (23%), Positives = 117/392 (29%), Gaps = 52/392 (13%)
Query: 83 PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS----CA 138
P P PPP P + P P+PP PP + S
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461
Query: 139 PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTL 198
P + P P+ P P P P P P P P A+ T
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP-----PTTTPSPPTTTPITPPASTTT 1516
Query: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPK-------------------PAAPGTVIQ 239
L +P + P P P P+ P T
Sbjct: 1517 ------LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 240 TPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP------PAPATLARPP-GHPAGPPT 292
TPP +PP PSPP P P PP P P T PP P PPT
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT 1630
Query: 293 AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352
+ +PP + P P P + P P P P SP +
Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP-PITTTTTPPPTTTPSSP--ITT 1687
Query: 353 AAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT-PTGLPKGAAGAVTQS 411
P T+ P +T +S P PS P P P T T P T +
Sbjct: 1688 TPSPPTTTMTTPSPTTTPSS----PITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743
Query: 412 LSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
++ P TTS + LT T L P + P +P
Sbjct: 1744 MTTLPPTTTS---SPLTTTPLPPSITPPTFSP 1772
Score = 85.9 bits (211), Expect = 2e-16
Identities = 123/564 (21%), Positives = 161/564 (28%), Gaps = 77/564 (13%)
Query: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125
SP + P +P PP P P P + P PPA+
Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK-PAGPAALAARAGPGPGPGPGPGPGP 184
PP + P P P+ P P P P P P P
Sbjct: 1515 TTLPPTTTPSP----PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 185 GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV 244
P P T S P P P P+ P T TPP
Sbjct: 1571 TPPPTTTPSPPTTTTPS-----------PPTITTTTPP----PTTTPSPPTTTTTTPPPT 1615
Query: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPP-----PAPATLARPPGHPAG---------- 289
+PP +PP + P P PPP P P T PP
Sbjct: 1616 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP 1675
Query: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKR 349
PPT P+ P + P+P P + P + P + SP
Sbjct: 1676 PPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP-- 1733
Query: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGALP---SPAAVPPPA------------- 393
P T+ P +T++ + P P SP + P
Sbjct: 1734 -TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWL 1792
Query: 394 -PGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNI----QN 448
G P G + + A RAT+ P V +L Q ++ +N
Sbjct: 1793 DSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKN 1852
Query: 449 FQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQP---QTTMAPRPATPTSAPPVQIST 505
PG V+ + + + QP TT P PT+ P +T
Sbjct: 1853 EDQKPGGVI------PMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTT 1906
Query: 506 VQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTAT 565
V TP + T T I TTV P+ T G Q T T T
Sbjct: 1907 VTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPT 1958
Query: 566 AVQTGTPQRTVPGATTTSSAATET 589
T TP T P TTT+ T T
Sbjct: 1959 PTGTQTP-TTTPITTTTTVTPTPT 1981
Score = 78.6 bits (192), Expect = 3e-14
Identities = 145/674 (21%), Positives = 188/674 (27%), Gaps = 79/674 (11%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 3814
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 3873
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 3874 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3931
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 3932 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 3976
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 3977 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4035
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 4036 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4090
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 4091 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 4142
Query: 565 TAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLAS-----SGKQSTETAAN 619
T T TP T P TTT+ T T + T + +G Q+
Sbjct: 4143 TPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHT 4201
Query: 620 VKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQL------TPDSAA 673
+ L E T + R SSP L PA+ TP +
Sbjct: 4202 STAPIAELTTSNPPPESSTPQTSRS-TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT 4260
Query: 674 FIQQSQQQPPPP---TSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQV 730
PPP TS T SS T T TSA P L+ P+ +
Sbjct: 4261 TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSII 4320
Query: 731 -GVGKQGQPTPLVI 743
G + P+ ++I
Sbjct: 4321 RTTGLRPYPSSVLI 4334
Score = 72.4 bits (176), Expect = 2e-12
Identities = 145/711 (20%), Positives = 195/711 (27%), Gaps = 89/711 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 3567 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 3626 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 3676
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 3735
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 3736 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3793
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 3794 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 3838
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 3839 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3897
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 3898 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3952
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I + T P+ T ++P P T + T
Sbjct: 3953 TVTPTPTPTGTQTPTTTPI---TTTTTVTPTPTPTGTQTPTTTP-------ITTTTTVTP 4002
Query: 565 TAVQTGTPQRTVPGATTTSS-------AATETMENVKKCKNFLSTLIKLASSGKQSTETA 617
T TGT T TTT++ T+T T + + T T
Sbjct: 4003 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062
Query: 618 ANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQ 677
V T+ + +P P P Q TP +
Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---------TPTGTQ-TPTTTPITTT 4112
Query: 678 SQQQP-PPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQG 736
+ P P PT T T + +++V T T + + PT G Q
Sbjct: 4113 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4172
Query: 737 ------QPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQ 781
T V P G PP T T P+ L + +TPQ
Sbjct: 4173 PTTTPITTTTTVTPTPTPTGTQTGPPTHTST-APIAELTTSNPPPESSTPQ 4222
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 1911 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 1969
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 1970 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 2020
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 2021 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 2079
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 2080 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2137
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 2138 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 2182
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 2183 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2241
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 2242 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2296
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 2297 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 2348
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 2349 TPTGTQTP-TTTPITTTTTVTPTPT 2372
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 2107
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 2108 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 2158
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 2159 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 2217
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 2218 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2275
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 2276 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 2320
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 2321 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2379
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 2380 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 2435 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 2486
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 2487 TPTGTQTP-TTTPITTTTTVTPTPT 2510
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 2187 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 2246 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 2296
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 2297 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 2355
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 2356 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2413
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 2414 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 2458
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 2459 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2517
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 2518 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2572
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 2573 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 2624
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 2625 TPTGTQTP-TTTPITTTTTVTPTPT 2648
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 2434
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 2435 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 2493
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 2494 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2551
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 2552 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 2596
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 2597 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2655
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 2656 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2710
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 2711 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 2762
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 2763 TPTGTQTP-TTTPITTTTTVTPTPT 2786
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 2572
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 2573 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 2631
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 2632 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2689
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 2690 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 2734
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 2735 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2793
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 2794 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2848
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 2849 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 2900
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 2901 TPTGTQTP-TTTPITTTTTVTPTPT 2924
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 2601 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 2660 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 2710
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 2711 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 2769
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 2770 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2827
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 2828 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 2872
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 2873 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2931
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 2932 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2986
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 2987 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 3038
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 3039 TPTGTQTP-TTTPITTTTTVTPTPT 3062
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 2798 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 2848
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 2849 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 2907
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 2908 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 2966 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 3010
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 3011 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 3070 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3124
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 3125 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 3176
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 3177 TPTGTQTP-TTTPITTTTTVTPTPT 3200
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 2986
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 2987 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 3045
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 3046 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3103
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 3104 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 3148
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 3149 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3207
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 3208 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3262
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 3263 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 3314
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 3315 TPTGTQTP-TTTPITTTTTVTPTPT 3338
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 3124
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 3125 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 3183
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 3184 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 3242 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 3286
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 3287 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3345
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 3346 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3400
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 3401 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 3452
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 3453 TPTGTQTP-TTTPITTTTTVTPTPT 3476
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 3153 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 3212 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 3262
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 3263 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 3321
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 3322 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3379
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 3380 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 3424
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 3425 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3483
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 3484 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3538
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 3539 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 3590
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 3591 TPTGTQTP-TTTPITTTTTVTPTPT 3614
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 3291 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 3350 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 3400
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 3401 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 3459
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 3460 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 3518 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 3562
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 3563 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3621
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 3622 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 3677 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 3728
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 3729 TPTGTQTP-TTTPITTTTTVTPTPT 3752
Score = 71.6 bits (174), Expect = 4e-12
Identities = 111/505 (21%), Positives = 139/505 (27%), Gaps = 63/505 (12%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 3538
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 3539 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 3597
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAA 336
P P T P P Q + P P G + P
Sbjct: 3598 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3655
Query: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP------ 390
P P P QT + P +T ++ PT G +P P
Sbjct: 3656 TPTP-------------TPTGTQTPTTT-PITTTTTVTPTPTPTGT-QTPTTTPITTTTT 3700
Query: 391 -PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
P P TPTG +T + + TPT T +G + T + P PT Q
Sbjct: 3701 VTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3759
Query: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQIS 504
P + + P Q TT+ P P TPT+ P +
Sbjct: 3760 TTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
TV TP + T T I TTV P+ T G Q T T
Sbjct: 3815 TVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTP 3866
Query: 565 TAVQTGTPQRTVPGATTTSSAATET 589
T T TP T P TTT+ T T
Sbjct: 3867 TPTGTQTP-TTTPITTTTTVTPTPT 3890
Score = 68.2 bits (165), Expect = 4e-11
Identities = 88/379 (23%), Positives = 109/379 (28%), Gaps = 46/379 (12%)
Query: 227 PLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGH 286
P P P T TP P P P P P P
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1968
Query: 287 PAGPPTAAPAVPPPAAAQNGG----SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGV 342
P T P P Q + P P G + P P P
Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-- 2026
Query: 343 KAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP-------PPAPG 395
P QT + P +T ++ PT G +P P P P
Sbjct: 2027 -----------TPTGTQT-PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTP- 2072
Query: 396 TPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGM 455
TPTG +T + + TPT T +G + T + P PT Q P
Sbjct: 2073 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-- 2130
Query: 456 VLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQISTVQAPG 510
+ + P Q TT+ P P TPT+ P +TV
Sbjct: 2131 ---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187
Query: 511 TPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTG 570
TP + T T I TTV P+ T G Q T T T T
Sbjct: 2188 TPTGTQTPTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQ 2239
Query: 571 TPQRTVPGATTTSSAATET 589
TP T P TTT+ T T
Sbjct: 2240 TP-TTTPITTTTTVTPTPT 2257
Score = 67.4 bits (163), Expect = 7e-11
Identities = 115/552 (20%), Positives = 156/552 (28%), Gaps = 61/552 (11%)
Query: 82 APGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP-PPEGSAGSCAPV 140
+P P P P P P + P P+PP + PP ++
Sbjct: 1700 SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTT 1759
Query: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP-----GKPAGPGAA 195
P ++ P +P P P G PG G GPG A
Sbjct: 1760 PLPPSITP-PTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWA 1818
Query: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG-------AAA 248
++ A + ++V + L+ + PG VI +
Sbjct: 1819 ANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCEC 1878
Query: 249 PPAPAAPSPPAAPAPAAPAAAP------PPPPPAPATLARPPGHPAGPPTAAPAVPPPAA 302
P + P P P P P P P P T P P
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1938
Query: 303 AQNGGSAGAAPA----PAPAAGGPAGVSGQPGPGAAAAAPAPG---------VKAESPKR 349
Q + P P G + P P P +
Sbjct: 1939 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1998
Query: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP-------PPAPGTPTGLPK 402
V P + P +T ++ PT G +P P P P TPTG
Sbjct: 1999 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTP-TPTGTQT 2056
Query: 403 GAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSEN 462
+T + + TPT T +G + T + P PT Q P +
Sbjct: 2057 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-----ITTT 2111
Query: 463 GQLLMIPQQALAQMQAQAHAQPQTTMAPRPA-----TPTSAPPVQISTVQAPGTPIIARQ 517
+ P Q TT+ P P TPT+ P +TV TP +
Sbjct: 2112 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2171
Query: 518 VTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVP 577
T T I TTV P+ T G Q T T T T TP T P
Sbjct: 2172 PTTTPI-----TTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTP 2222
Query: 578 GATTTSSAATET 589
TTT+ T T
Sbjct: 2223 ITTTTTVTPTPT 2234
Score = 62.4 bits (150), Expect = 2e-09
Identities = 89/431 (20%), Positives = 122/431 (28%), Gaps = 77/431 (17%)
Query: 386 PAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRL-PQPPQNPT 444
P P P P + T LP + + + TP TT+ T T P P PP + T
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461
Query: 445 NIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIS 504
P P + P TT P T T +PP
Sbjct: 1462 TTPPPTTTPS--------------PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTT-- 1505
Query: 505 TVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTA 564
P TP + P T TT P T P P + T +L
Sbjct: 1506 ---TPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTP---ITPPTSTTTLPPT 1559
Query: 565 TAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELV 624
T T P TTT S T T + +T ++ T T
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPP---TITTTTPPPTTTPSPPTTTT------- 1609
Query: 625 QNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPP 684
++P P P S P +TP ++ P P
Sbjct: 1610 ----------------------TTPPPTTTP----SPPTTTPITPPTSTTTLPPTTTPSP 1643
Query: 685 PTSQATTALTAVVLSSSVQRTAGKTAAT-------------VTSALQPPVLSLTQPTQVG 731
P + TT S T T +T+ PP ++T P+
Sbjct: 1644 PPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT 1703
Query: 732 VGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPV 791
+P+ P PP T+T P M T P +PL
Sbjct: 1704 TPS----SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTT 1759
Query: 792 PVVKPAVLPGT 802
P + P++ P T
Sbjct: 1760 P-LPPSITPPT 1769
Score = 59.3 bits (142), Expect = 2e-08
Identities = 87/423 (20%), Positives = 120/423 (28%), Gaps = 35/423 (8%)
Query: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG-P 163
P P + P P P G+ + P P P P G P P
Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062
Query: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
P P P P P T P + +
Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTP--------ITTTTTVTPTPTPTGTQTPTTTPITT-TT 4113
Query: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPA---APSPPAAPAPAAPAAAPPPPPPAPATL 280
+ P P P T TP P P +P P P P P T
Sbjct: 4114 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 4172
Query: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP--AAGGPAGVSGQPGPGAAAAAP 338
P P T P P Q G + AP P S P + ++P
Sbjct: 4173 --PTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP 4230
Query: 339 APGVKAESPKRVVQAAPPAAQTLAASGPAS-TAASMVIGPTMQGALPSPAAVPP--PAPG 395
++ PPA + + + P++ TA + G PS PP P G
Sbjct: 4231 -----LTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRG 4285
Query: 396 TPTG---LPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLP 452
T TG P + T + + TPT T + + T L P P + +
Sbjct: 4286 TTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP-YPSSVLICCVLNDTYYA 4344
Query: 453 PGMVLVRSENGQLLMIPQQALA----QMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQA 508
PG + G +L+ + P T P +TPT + P +
Sbjct: 4345 PGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPT 4404
Query: 509 PGT 511
PGT
Sbjct: 4405 PGT 4407
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 102 bits (253), Expect = 3e-21
Identities = 115/392 (29%), Positives = 151/392 (38%), Gaps = 68/392 (17%)
Query: 74 GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133
GP PA APE P R P+ P P+ P P P PAA + P E +
Sbjct: 973 GPVTPATTVH--APEEPDTAAVRVST--PEEPASPAAAVP-TPEEPTSPAAAVPTPEEPT 1027
Query: 134 AGSCA-PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG-PGPGKPAG 191
+ + A P P A P P P PA A P P P P P +P
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAA-------AVPTPEEPTSPAAAVPTPEEPTS 1080
Query: 192 PGAA-----QTLNGSAALLNSHHAAAPAVSLVNN----GPAALLPLPK-PAAPGTVIQTP 241
P AA + + +AA+ +PA ++ PAA +P P+ PA+P + TP
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP 1140
Query: 242 PFVGAAAPPAPAAPSPP-------AAPAP---AAPAAAPPPPPPAP------ATLARPPG 285
A PAPA P+P A P P A+PAAA P P + ATL P
Sbjct: 1141 E---EPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS 1197
Query: 286 HPAGPPTAA-----------PAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334
A PT A PA P + + A A P A V P ++
Sbjct: 1198 PAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSS 1257
Query: 335 AAAPAPGVKAESPKRVV----QAAPPAAQTLAASGPASTAASMV---IGPTMQGALPSP- 386
AAA + SP V + A PAA PAS AA++ + ++P+P
Sbjct: 1258 AAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE 1317
Query: 387 ------AAVPPPAPGTPTGLPKGAAGAVTQSL 412
AAVPP +P G+P A T S+
Sbjct: 1318 VPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSV 1349
Score = 100 bits (249), Expect = 7e-21
Identities = 138/545 (25%), Positives = 182/545 (33%), Gaps = 98/545 (17%)
Query: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162
QRP R VP A L P EG++ + P P AV A P P A
Sbjct: 832 QRPS----RTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887
Query: 163 PAALA---ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG--------SAALLNSHHAA 211
+L A P P P G A ++ +AA+ +A
Sbjct: 888 IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSA 947
Query: 212 APAVSLVNNGPAALLPLPK-------PAAPGTVIQTP---------------PFVGAAAP 249
S A +P+ + P P T + P P AAA
Sbjct: 948 VAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAV 1007
Query: 250 PAPAAPSPPAAPA-----PAAPAAAPPPP--PPAPATLARPPGHPAGPPTAAPAVPPPAA 302
P P P+ PAA P +PAAA PPP P +PA P P P A P P +
Sbjct: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
Query: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV----QAAPPAA 358
A A P P A V P + AAA + SP V + A PAA
Sbjct: 1068 -----PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
Query: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTP-- 416
PAS AA++ PT P A P PA TP A T S +P
Sbjct: 1123 AVPTPEEPASPAAAV---PT-----PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAA 1174
Query: 417 -------TATTSGIRATL-TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMI 468
+A+ + + ATL PT A +P P ++ F P V E L
Sbjct: 1175 AVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASL--- 1231
Query: 469 PQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVS 528
A A + P+ +P A PT P T A +TP + +
Sbjct: 1232 ---------AAAVSNPEEPTSPAAAVPTLEEP----------TSSAAAVLTPEELSSPAA 1272
Query: 529 QAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATE 588
T +P++ ++ A T + A TP+ VP +AA
Sbjct: 1273 SVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE--VP---AIPAAAVP 1327
Query: 589 TMENV 593
ME V
Sbjct: 1328 PMEEV 1332
Score = 75.1 bits (183), Expect = 3e-13
Identities = 83/266 (31%), Positives = 102/266 (38%), Gaps = 51/266 (19%)
Query: 47 TPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPG 106
TPE + A A+ SPA A P E AA P P A P P
Sbjct: 1074 TPEEPTSPAAAVPTPEEPTSPAAAV----PTPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
Query: 107 PPSPRR----PLVPAGPAPP---------AAKLRPPPEGSAGSCAPVPA-------AAAV 146
P SP P PA PAP AA P PE SA A VP AA V
Sbjct: 1130 PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVV 1189
Query: 147 AAGPEPAPAGPAKPAGPAAL----------AARAGPGPGPGPGPGPGPGPGKPAGPGAA- 195
A EP + P PAA+ AA P P +P P AA
Sbjct: 1190 ATLEEPTSPAASVPT-PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAV 1248
Query: 196 ----QTLNGSAALLNSHHAAAPAVSLVN-----NGPAALLPLPKPAAPGTVIQTPPFVGA 246
+ + +AA+L ++PA S+ + AA+ L +PA+P + TP
Sbjct: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE---V 1305
Query: 247 AAPPAPAAPSPPAAPAPAAPAAAPPP 272
AA PA + P+P PA PAAA PP
Sbjct: 1306 AAIPAASVPTP---EVPAIPAAAVPP 1328
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 102 bits (253), Expect = 3e-21
Identities = 114/412 (27%), Positives = 130/412 (31%), Gaps = 63/412 (15%)
Query: 54 AAGALGNHVVSGSPAGAAGAGPAAPA--------EGAPGAAPEPPPAG-RARPGGGGPQR 104
A G GN G P A G PA G PG P PAG + PG GPQ
Sbjct: 1070 ALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG 1129
Query: 105 P-GPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163
P G + P+ GPA P P +G G + E P GP P GP
Sbjct: 1130 PAGRDGLQGPVGLPGPAGPVGP--PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP 1187
Query: 164 AALAARAGPGPGPGP-------------GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA 210
+G PGP GP PGP P G G
Sbjct: 1188 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247
Query: 211 AAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAA-PSPPAAPAPAAP--- 266
P GP+ P P I P VG P A P P P P
Sbjct: 1248 MGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGE 1307
Query: 267 -----------AAAPPPPP-----------PAPATLARPPGHPAGPPTAAPAVPPPAAAQ 304
AA PP P P P PG P P A PP
Sbjct: 1308 RGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD 1367
Query: 305 NG--GSAGA-APAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL 361
+G G G+ P P GP G G PGP A G K + ++ P +
Sbjct: 1368 DGEPGQTGSPGPTGEPGPSGPPGKRGPPGP--AGPEGRQGEKGAKGEAGLEGPPGKTGPI 1425
Query: 362 AASG----PASTAASMVIGPTMQGALP-SPAAVPPPAPGTPTGLP--KGAAG 406
G P + GP + LP SP PP P P GLP KG +G
Sbjct: 1426 GPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSG 1477
Score = 96.3 bits (238), Expect = 1e-19
Identities = 133/463 (28%), Positives = 148/463 (31%), Gaps = 72/463 (15%)
Query: 42 HLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPA--EGAPGAAPEPPPAGR-ARPG 98
H P P G G G P A G P G PG P P G G
Sbjct: 1016 HPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKG 1075
Query: 99 GGGPQRPGPPSPRRPLVPAGPAPPAAKL----RPPPEGSAGSCAPV----------PAAA 144
GP PGPP P GPA A + RP P+G G PA
Sbjct: 1076 NEGP--PGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133
Query: 145 AVAAGPE--PAPAGPAKPAGPAALAARAG----------------PGP----GPGPGPGP 182
GP P PAGP P G G PGP GP PGP
Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193
Query: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242
G+P GP Q L G P GP L LP P PG +T
Sbjct: 1194 SGADGEP-GPRGQQGLFGQKGDEGPRGFPGPP------GPVGLQGLPGP--PGEKGETGD 1244
Query: 243 FVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP----PPAPATLARP--PGHPAGPPTAAPA 296
VG PP P P P+ AP A PP P A P G P P P
Sbjct: 1245 -VGQMGPPGPPGPRGPSG-APGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPP 1302
Query: 297 VPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG-PGAAAAAPAPGVKAESPKRVVQAAP 355
P + G S + A P GP G G G PG PG E P Q P
Sbjct: 1303 GPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGE-PGPAGQDGP 1361
Query: 356 PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP----PPAPGTPTGLPKGAAGAVTQS 411
P + P T + GPT + P P+ P PP P P G +G GA ++
Sbjct: 1362 PGDKG-DDGEPGQTGSP---GPTGE---PGPSGPPGKRGPPGPAGPEG-RQGEKGAKGEA 1413
Query: 412 LSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPG 454
P T I P P + P Q PG
Sbjct: 1414 GLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG 1456
Score = 96.3 bits (238), Expect = 1e-19
Identities = 135/470 (28%), Positives = 154/470 (32%), Gaps = 124/470 (26%)
Query: 55 AGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR-------ARPGGGGPQRP-- 105
AGA G + G P GPA +GAPG PAGR PG GP P
Sbjct: 1095 AGAAGPIGIPGRPGPQGPPGPAGE-KGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPG 1153
Query: 106 -----------------------GPPSPRRPLVPAG-PAPPAAKLRPPPEGSAGSCA--- 138
GPP P P P G P P A P P G G
Sbjct: 1154 EDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKG 1213
Query: 139 ----------PVPAAAAVAAGP-----------EPAPAGPAKPAGPAALAARAGPGPGPG 177
P P GP + P GP P GP+ GP PG
Sbjct: 1214 DEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPG 1273
Query: 178 ----PG-------PG----PG-PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
PG PG PG PG G P GP + G + + P ++G
Sbjct: 1274 GIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDG 1333
Query: 222 PAALL-PLPKPAAPGTVIQTPPFVGAAAPPAP----------AAPSPPAAPAPAAPAAAP 270
P P+ P PG + P G PP +P P P P+ P
Sbjct: 1334 PKGSPGPVGFPGDPGPPGEPGP-AGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392
Query: 271 PPPPPA-------------PATLARPPGHPAGP--PTAAPAVPPPAAAQN-GGSAGAAPA 314
PP PA A L PPG GP P AP P P + G G
Sbjct: 1393 GPPGPAGPEGRQGEKGAKGEAGLEGPPGK-TGPIGPQGAPGKPGPDGLRGIPGPVGEQGL 1451
Query: 315 P-APAAGGPAGVSGQPG-PGAAAAAPAPGVKAESPKRVVQAAPPAAQ----------TLA 362
P +P GP G G PG PG + G K P + PP Q
Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGH-PGLIGLIGPPGEQGEKGDRGLPGPQG 1510
Query: 363 ASGPAS----TAASMVIGPTMQGALPSPAAVPPPAPGT--PTGLPKGAAG 406
+SGP T S IGP LP P P A G+ PTG PKG AG
Sbjct: 1511 SSGPKGEQGITGPSGPIGPPGPPGLPGPPG-PKGAKGSSGPTG-PKGEAG 1558
Score = 95.5 bits (236), Expect = 2e-19
Identities = 124/431 (28%), Positives = 137/431 (31%), Gaps = 106/431 (24%)
Query: 56 GALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLV 115
G G V G P GP G PG P A + G G P +PGP R P
Sbjct: 862 GEKGKLGVPGLPGYPGRQGPKGSI-GFPGF----PGANGEKGGRGTPGKPGPRGQRGPTG 916
Query: 116 PAGPAPPAAKL-RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGP 174
P G P +P P+G++G P AGP P GP P GP GP
Sbjct: 917 PRGERGPRGITGKPGPKGNSGGDGP--------AGP-PGERGPNGPQGPTGFPGPKGPPG 967
Query: 175 GPG----PG-PG-------------PGP-------------------GPGKPAGPGAAQT 197
PG PG PG PGP G P GP Q
Sbjct: 968 PPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQG 1027
Query: 198 LNGSAALLNSHHAAAPAVSLVNNGPAALLPLP-KPAAPGTV--IQTPPFVGAAAPPAPAA 254
L G A + PA +GP L P PG V + G PP PA
Sbjct: 1028 LPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAG 1087
Query: 255 PSPPAAPAPAA-----PAAAPPPPPPAPATLARPPGH-----PAG----------PPTAA 294
PA AA P P PP PA PG PAG P A
Sbjct: 1088 SPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAG 1147
Query: 295 PAVPP-----------PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP--- 340
P PP P + G G P P GP G GQPGP A P P
Sbjct: 1148 PVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPT--GPQGPIGQPGPSGADGEPGPRGQ 1205
Query: 341 ----GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396
G K + R P GP P +G + PP P
Sbjct: 1206 QGLFGQKGDEGPRGFPGPPGPVGLQGLPGP----------PGEKGETGDVGQMGPPGPPG 1255
Query: 397 PTGLPKGAAGA 407
P G P GA GA
Sbjct: 1256 PRG-PSGAPGA 1265
Score = 94.7 bits (234), Expect = 4e-19
Identities = 98/326 (30%), Positives = 112/326 (34%), Gaps = 47/326 (14%)
Query: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102
+ P P +GA G G P G G A +G PG A EP PG GGP
Sbjct: 1248 MGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG-AVGEKGEPGEAGEP-----GLPGEGGP 1301
Query: 103 QRPGPPSPRRPLVPAGPA----PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPA 158
PGP R +GP+ PP K P +G GS PV EP PAG
Sbjct: 1302 --PGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359
Query: 159 KPAGPAALAARAGPGPGPGPGPGPGP-------GPGKPAGPGAAQTLNGSAALLNSHHAA 211
P G G PGP PGP GP PAGP Q G
Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKG----------- 1408
Query: 212 APAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP-PAAPAPAAPAAAP 270
A + + P P+ APG P G P P P +P P P P
Sbjct: 1409 AKGEAGLEGPPGKTGPIGPQGAPG----KPGPDGLRGIPGPVGEQGLPGSPGPDGP-PGP 1463
Query: 271 PPPPPAPATLA-RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG--------G 321
PP P P G P + PP G G P P ++G G
Sbjct: 1464 MGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRG-LPGPQGSSGPKGEQGITG 1522
Query: 322 PAGVSGQPGPGAAAAAPAP-GVKAES 346
P+G G PGP P P G K S
Sbjct: 1523 PSGPIGPPGPPGLPGPPGPKGAKGSS 1548
Score = 89.0 bits (219), Expect = 2e-17
Identities = 109/381 (28%), Positives = 120/381 (31%), Gaps = 50/381 (13%)
Query: 54 AAGALGNHVVSGSPAGAAGAGPAAPA--EGAPGAAPEPPPAGRARPGGGGPQRPGPPSPR 111
A G G G P GP P G G +P P G + GG GP GPP R
Sbjct: 893 ANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNS--GGDGPA--GPPGER 948
Query: 112 RPLVPAGPAP-PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170
P P GP P K P P G G + P GP GP
Sbjct: 949 GPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET 1008
Query: 171 GP-GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLP 229
GP G PGP PGP PG+ Q L G A + PA +GP L P
Sbjct: 1009 GPMGERGHPGP-PGP-PGE-------QGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFP 1059
Query: 230 KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG 289
+ G PP P P P +P PA A A P G P
Sbjct: 1060 GDRGLPGPVGALGLKGNEGPPGP--PGPAGSPGERGPAGA-----------AGPIGIPGR 1106
Query: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP-------GAAAAAPAPGV 342
P P P G PA GP G+ G GP G PG
Sbjct: 1107 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQ 1166
Query: 343 KAESPKRVVQAAP-PAAQTLAASGPASTAASMVIGPTMQGAL------PSPAAVP-PPAP 394
K + Q P P P + A GP Q L P P PP P
Sbjct: 1167 KGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGP 1226
Query: 395 GTPTGLP-----KGAAGAVTQ 410
GLP KG G V Q
Sbjct: 1227 VGLQGLPGPPGEKGETGDVGQ 1247
Score = 75.1 bits (183), Expect = 3e-13
Identities = 123/474 (25%), Positives = 145/474 (30%), Gaps = 88/474 (18%)
Query: 25 LVGSLESQLAASAAHHHHLAPRTPEV------RAAAAGALGNHVVSGSPAGAAGAGPAAP 78
+V + ESQ A + LA R P R G G+ + G P GP
Sbjct: 538 MVSAQESQ-AQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRG- 595
Query: 79 AEGAPGAAPEPPPAGRA-------RPGGGGPQR----------PGPPSPRRPLVPAGPAP 121
+G PG A +P GRA PG GP+ PG R P+GP
Sbjct: 596 VQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPG 655
Query: 122 PAAKLRPPPEGSAGSCAPV-PAAAAVAAGPEP--APAGPAKPAGPAALAARAG-PGPGPG 177
P P +G G V P GP P GP P GP + G PGP
Sbjct: 656 P-----PGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGN 710
Query: 178 PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTV 237
GP PGP G AQ L G + P PL KP PG
Sbjct: 711 VGPQGEPGPPGQQGNPGAQGLPGPQGAIGP--------------PGEKGPLGKPGLPG-- 754
Query: 238 IQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV 297
GA PP P P PP P P P G
Sbjct: 755 -----MPGADGPPGHPGKEGP----PGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKG 805
Query: 298 PPPAAAQNG-----------GSAGAAPAPAPAA-GGPAGVSGQPGPGAAAAAPAP-GVKA 344
++G G G P P GP G G+ GP P P G
Sbjct: 806 TKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD---PGPLGPPG 862
Query: 345 ESPKRVVQAAPPAAQTLAASG----PASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL 400
E K V P G P A+ +G +P P PTG
Sbjct: 863 EKGKLGVPGLPGYPGRQGPKGSIGFPGFPGAN-----GEKGGRGTPGKPGPRGQRGPTG- 916
Query: 401 PKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPG 454
P+G G + P + G P R P PQ PT + PPG
Sbjct: 917 PRGERGPRGITGKPGPKGNSGGDGPAGPP---GERGPNGPQGPTGFPGPKGPPG 967
Score = 75.1 bits (183), Expect = 3e-13
Identities = 104/415 (25%), Positives = 122/415 (29%), Gaps = 85/415 (20%)
Query: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP 107
P+ G GN G P GP P E P P P A G P + GP
Sbjct: 713 PQGEPGPPGQQGNPGAQGLPGPQGAIGP--PGEKGPLGKPGLPGMPGADGPPGHPGKEGP 770
Query: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA-------------- 153
P + P GP P P P G G+ E
Sbjct: 771 PGEKGGQGPPGPQGPIGY--PGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828
Query: 154 ----PAGPAKPAGPAALAARAGPGPGPGPGPGPG-------PG-PGKPAGPGAAQTL--- 198
P GP GP R GP PGP PG PG PG P G ++
Sbjct: 829 GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFP 888
Query: 199 -----------NGSAALLNSHHAAAPAVSLVNNGPAALL--PLPKPAAPGTVIQTPPFVG 245
G+ P GP + P PK + G G
Sbjct: 889 GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGD--------G 940
Query: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQN 305
A PP P+ P P P PP PP L PGHP +
Sbjct: 941 PAGPPGERGPNGPQGPT-GFPGPKGPPGPPGKDGL---PGHPG------------QRGET 984
Query: 306 GGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP-------GVKAESPKRVVQAAPPAA 358
G P P GP G +G+ GP P P G+ + K + P A
Sbjct: 985 GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPA 1044
Query: 359 QTLAASGPASTAA----SMVIGPTMQGALPSPAAVPPPAPGTPTGLP--KGAAGA 407
GP + GP GAL PP P P G P +G AGA
Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPV--GALGLKGNEGPPGPPGPAGSPGERGPAGA 1097
Score = 72.0 bits (175), Expect = 3e-12
Identities = 77/269 (28%), Positives = 87/269 (32%), Gaps = 50/269 (18%)
Query: 55 AGALGNHVVSGSPAGAAGAGPAAPA--EGAPGAAPEPPPAGRARPGG------------- 99
+GA G G P G P G PG EP PAG+ P G
Sbjct: 1317 SGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS 1376
Query: 100 ----GGPQRPGPPSPRRPLVPAGP----APPAAKLRPPPEGSAGSCAPV-PAAAAVAAGP 150
G P GPP R P PAGP AK EG G P+ P A GP
Sbjct: 1377 PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGP 1436
Query: 151 EPAPAGPAKPAGPAALAARAGPGPGPGP-GP----------GPGPGPGKPA-----GPGA 194
+ P P G L GP PGP GP GP G P GP
Sbjct: 1437 DGLRGIPG-PVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPG 1495
Query: 195 AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAA 254
Q G L ++ P GP+ P+ P PG G P
Sbjct: 1496 EQGEKGDRGLPGPQGSSGPKGEQGITGPSG--PIGPPGPPG-------LPGPPGPKGAKG 1546
Query: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARP 283
S P P A PP PP P + +P
Sbjct: 1547 SSGPTGPKGEAGHPGPPGPPGPPGEVIQP 1575
Score = 67.8 bits (164), Expect = 5e-11
Identities = 101/355 (28%), Positives = 109/355 (30%), Gaps = 73/355 (20%)
Query: 56 GALGNHVVSGSPA----GAAGAGPAAPAEGAPGAAPEPPPAGRARPGG--GGPQRPGPPS 109
G G G PA G GP P G A P P G P G G P GPP
Sbjct: 447 GPRGEKGQKGEPAIIEPGMLIEGPPGPE----GPAGLPGPPGTMGPTGQVGDPGERGPPG 502
Query: 110 PRRPLVPAG---PAPPAAKLRPPPE----GSAGSCAPVPAAAAVAAGP--EPAPAGPAKP 160
RP +P P PP L P G AGS P+ +A A + A P
Sbjct: 503 --RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGP 560
Query: 161 AGPAALAARAGPGPGPGPG-----PGP----GP----GPGKPAGPGAAQTLNGSAALLNS 207
AGP L R GP PG G PG GP GP PAG + GS
Sbjct: 561 AGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGM 620
Query: 208 HHAAAPAVSLVNNGPAALL----------PLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP 257
P +G A L P P PG + P P P
Sbjct: 621 PGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGP 680
Query: 258 PAAPAPAAPAAAPPPP-------PPAPATLARPPGHPAGP-----------PTAAPAVPP 299
P P P PP P P P G P P P A+ P
Sbjct: 681 RGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740
Query: 300 PAAAQNGGSAGAAPAPA-------PAAGGPAGVS---GQPGPGAAAAAPAP-GVK 343
P G G P P GP G G PGP P P GVK
Sbjct: 741 PGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVK 795
Score = 61.2 bits (147), Expect = 5e-09
Identities = 67/209 (32%), Positives = 75/209 (35%), Gaps = 39/209 (18%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAG-RARPGGGGPQ 103
P PE R GA G + G P GP +GAPG +P P G R PG G Q
Sbjct: 1397 PAGPEGRQGEKGAKGEAGLEGPPGKTGPIGP----QGAPG---KPGPDGLRGIPGPVGEQ 1449
Query: 104 R-PGPPSPRRPLVPAGPAP-PAAKLRPPPEGSAGSCAPVPAAAAVAAGPE------PAPA 155
PG P P P P GP P K P+G G + E P P
Sbjct: 1450 GLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1509
Query: 156 GPAKPAGPAALAARAGP--GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAP 213
G + P G + +GP PGP PGP PGP G G A H P
Sbjct: 1510 GSSGPKGEQGITGPSGPIGPPGPPGLPGP-PGPKGAKGSSGPTGPKGEAG-----HPGPP 1563
Query: 214 AVSLVNNGPAALLPLPKPAAPGTVIQTPP 242
GP P PG VIQ P
Sbjct: 1564 -------GP--------PGPPGEVIQPLP 1577
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 101 bits (252), Expect = 3e-21
Identities = 223/997 (22%), Positives = 346/997 (34%), Gaps = 181/997 (18%)
Query: 86 APEPPPAGRARPGGGGPQRPG----PPSPRRPLVPAGPAPPAAKLRP---------PPEG 132
+P PP + PG Q+PG P P +P PA P+ +P PP
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-----PAQPSGLTKPLAQQPGTVKPPVQ 354
Query: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPA----GPAALAARAGPGPGPGPGPGPGPGPGK 188
G+ P PA A P G KP+ GP ALA G G P PGP P +
Sbjct: 355 PPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413
Query: 189 PAG---PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245
G P A Q P P P T +Q P G
Sbjct: 414 QVGTPKPLAQQ-------------------------PGLQSPAKAPGPTKTPVQQP---G 445
Query: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQN 305
PA A P A PP P P A+PP P PA PPP
Sbjct: 446 PGKIPAQQA-GPGKTSAQQTGPTKPPSQLPGP---AKPP-----PQQPGPAKPPPQ---- 492
Query: 306 GGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG 365
G+A P+ G QPGP A +P + P + +A P+AQ + +
Sbjct: 493 --QPGSAKPPSQQPGSTKPPPQQPGP--AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
Query: 366 PASTAASMVIGPTMQGALPSPAAVPPPAPGTPT-GLPKGAAGA--VTQSLSRTPTATTSG 422
P++ ++ + T G P V P A P+ GLPK T+ L P
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 423 IRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQ----- 477
TV + P + T ++ + L + R+ G L +P +++
Sbjct: 609 TCTECQTTVCSLCGFNPNPHLTEVKEW-LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVT 667
Query: 478 -----AQAHAQPQTTMAPRPATPTSAPPVQISTVQAP-GTPIIARQVT----PTTIIKQV 527
+++ QPQ T + A AP +S P P + +Q T P+ KQ
Sbjct: 668 TTSAVSKSSPQPQQTSPKKDA----APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP 723
Query: 528 SQAQTTVQPSATLQRS-PGVQPQ-------------------LVLGGAAQTASLGTATAV 567
+A + +P+ + S P Q + LV +A T ++ V
Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
Query: 568 QTGTPQRTVPGATTTSSAATETMENV-KKCKNFLSTLI-KLASSGKQSTETAANVKELVQ 625
Q+ ++T P T S+ +++ +K F S I + AS K + + + Q
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ 843
Query: 626 NLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPP 685
+D + E+ + SP+P P K S P P + + QQ P P
Sbjct: 844 KQVDPVQKKEEPKK---AQTKMSPKPDAKPMPKGS-PTPPGPRPTAGQTVPTPQQSPKPQ 899
Query: 686 TSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQ 745
+L ++ + + TVT L S+ + GQP P
Sbjct: 900 EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP---HS 956
Query: 746 PPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKAL 805
PGA ++ Q P + P + Q P + +PV K P + L
Sbjct: 957 QSGPGAPMK--QAPAPSQPPTSQGPP------KSTGQAPPAPAKSIPVKKETKAPAAEKL 1008
Query: 806 SAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELVGTLTR 865
+ QA ++ + + + I D S+ +E +L T L +
Sbjct: 1009 EPKAEQAPTVKRTETE-------KKPPPIKDSKSLT----AEPQKAVLPTK------LEK 1051
Query: 866 SCKDETFLLQAPLQRRILEIGKK-----HGITELHPDVVSYVSHATQQRLQNLVEKISET 920
S K E+ PL + L IG K + TE V + L + E +
Sbjct: 1052 SPKPES---TCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLN 1108
Query: 921 AQ-QKNFSYKDDD---------------------RYEQASDVRAQLKFFEQLDQIEKQRK 958
Q Q+ S + D Q + V Q+K ++ +Q + K
Sbjct: 1109 CQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ---EVK 1165
Query: 959 DEQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQE 995
E E+ IL + ++ S ++ P + QK +E + ++
Sbjct: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK 1202
Score = 69.3 bits (168), Expect = 2e-11
Identities = 143/656 (21%), Positives = 216/656 (32%), Gaps = 116/656 (17%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
P V+ G + A GP P PG P PP + P PQ+
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG--PAKPPPQQPGPAKPPPQQ 493
Query: 105 PG---PPSPRRPLVPAGPAPPAAKLRP--PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK 159
PG PPS + P PP + P P GS P P+ +A P PAK
Sbjct: 494 PGSAKPPSQQ----PGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAK 548
Query: 160 PAGPAALAARAGPGPG-PGPGPGPGPGPGKPAGPGAAQTL----NGSAALLNSHHAA--- 211
P+ + + G G P P P +P G +T+ N + LL+ A
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 212 ------APAVSLVNNGPAALLP--------------------LPKPAAPGTVIQTPPFVG 245
SL P L P P++P ++T P
Sbjct: 609 TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTT 668
Query: 246 AAA----PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301
+A P P SP AP + P P P + +P H G P+A PP A
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH--GSPSAKAKQPPEA 726
Query: 302 AAQNGGSAGAAPA-PAPAAGGPAGVSGQPGPGAA------AAAPAPGVKAESPKRVVQA- 353
+ + + P+ P+ P P ++ + K + P VQ+
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
Query: 354 -----APPAAQTLAASGPASTAASMVIGPTMQGALPSPAA----VPPPAPGTPT------ 398
PP A + + P A+P PA+ + P P + +
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 399 ------GLPKGAAGAVTQSLSRTP----TATTSGIRATLTPTVLAPRLPQPPQNPTNIQN 448
PK A ++ P + T G R T TV P+ PQ + +
Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS--RR 904
Query: 449 FQLPPGMVL----------VRSENGQLLMIPQQALAQM--------QAQAHAQ--PQTTM 488
F L G + + G+L +Q Q H+Q P M
Sbjct: 905 FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPM 964
Query: 489 --APRPATPTSAPPVQISTVQAPGTPIIARQVTPTT------IIKQVSQAQTTVQPSATL 540
AP P+ P ++ ST QAP P + V T ++ ++ TV+ + T
Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 541 QRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKC 596
++ P ++ L Q A L T ++ P+ T P T + ++ N C
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLE-KSPKPESTCPLCKTELNIGSKDPPNFNTC 1079
Score = 63.9 bits (154), Expect = 8e-10
Identities = 164/759 (21%), Positives = 245/759 (32%), Gaps = 108/759 (14%)
Query: 91 PAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGP 150
P G A G G SP +PAG ++L S + A + A G
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQL------SEEERRQIAAVMSRAQGL 66
Query: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG-----------AAQTLN 199
PA P+ + P G P PG+PA PG + Q L
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
Query: 200 GSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA 259
G + S + L ++++ PG + + ++ P
Sbjct: 127 GRSPSTISLKESKSRTDLKEEHKSSMM-------PGFLSEVNALSAVSSVVNKFNPFDLI 179
Query: 260 APAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA 319
+ + A+ +P G P P P P G P
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPK------QQGPGRDPLQQD 233
Query: 320 GGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ---AAPPAAQTLAASGPASTAASMVIG 376
G P +S Q + P G + P + Q A P + AS P + A +V G
Sbjct: 234 GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRD--ASRPQTKQADIVRG 291
Query: 377 PTMQGALPSPAAVP--PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIR-------ATL 427
+++ +LPSP+ P P PG P G +Q P A SG+ T+
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPG--HEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349
Query: 428 TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTT 487
P V P +PP P P SE +ALAQ Q
Sbjct: 350 KPPVQPPGTTKPPAQPLG----PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-- 403
Query: 488 MAPRPATPTSAPPVQIST----VQAPGTPIIARQVTPT-TIIKQVSQAQTTVQPS----A 538
P PA P P Q+ T Q PG A+ PT T ++Q + Q +
Sbjct: 404 -QPGPAKP---PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 539 TLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKN 598
+ Q++ +P L G A+ A P PG+ S + + +
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPA----KPPPQQPGSAKPPSQQPGSTKPPPQQPG 515
Query: 599 FLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSP--QPYLVPF 656
+ S K ++ + K Q K A+ T + + + P P + P
Sbjct: 516 PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPS 575
Query: 657 LK----RSLP----------ALRQLTPDSAAFIQQSQQQPP-------PPTSQATTALTA 695
K + LP L P+ A F ++ Q P T
Sbjct: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635
Query: 696 VVLSSSVQRTAGKTAATVTSALQP-----PVL-------SLTQPTQVGVGKQGQPTPLVI 743
+ L+ ++R G A V S+ QP PV S QP Q K P +
Sbjct: 636 LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695
Query: 744 Q--QPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTP 780
+ +P KP L++ P TL +P +QP L+ P
Sbjct: 696 KAPEPKKPPPLVKQP--TLHGSPSAKAKQPPEADSLSKP 732
Score = 63.9 bits (154), Expect = 8e-10
Identities = 77/346 (22%), Positives = 117/346 (33%), Gaps = 49/346 (14%)
Query: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP--APAT 279
PA+ LP P+ + PF +++ A P PP P P P PPPPPP P T
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 280 LARPPGHP------AGPPT-------AAPAVPPPAAAQNGG---SAGAAPAPAPAAGGPA 323
+P P A P T A + A ++ G + AP P P+
Sbjct: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491
Query: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383
+ P P P +PK V+ P Q P T S+ T+
Sbjct: 2492 SI---PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548
Query: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
+ +P P T LS ++ +LT T + LP P P
Sbjct: 2549 SADYKLPSP----------------TSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTP 2592
Query: 444 TNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQI 503
T+ Q + L P + L ++ P T P + +
Sbjct: 2593 TDSSASQ---------AITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISG 2643
Query: 504 STVQAPGTPIIAR---QVTPTTIIKQVSQAQTTVQPSATLQRSPGV 546
+ TP+ A Q PT++ + ++ + + SAT +P V
Sbjct: 2644 ALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSV 2689
Score = 55.8 bits (133), Expect = 2e-07
Identities = 199/1026 (19%), Positives = 339/1026 (33%), Gaps = 170/1026 (16%)
Query: 57 ALGNHV--VSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPL 114
ALG + V SP P ++P+P + P P++P
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP- 703
Query: 115 VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP------------APAGPAKPAG 162
PP K +P GS + A P A + P P AP KP
Sbjct: 704 ------PPLVK-QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 163 PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG- 221
P + P P P+ +Q + L + +A P+ S G
Sbjct: 757 PKMVK----PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT-DSAKPSQSFPPTGE 811
Query: 222 ---PAALLPLPKPAAPGTVIQTP-------------PFVGAAAP---PAPAAPSPPAAPA 262
P +P+PA+ +I P P P +P P A P
Sbjct: 812 KVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPM 871
Query: 263 PAAPAAAPPPPPPAPATLARPPGHP------------AGPPTAAPAVPPPAAAQN----- 305
P P P P A T+ P P G T AP P +
Sbjct: 872 PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931
Query: 306 ---GGSAGAAPAPAPAAGGPAGVSGQPGPGA-AAAAPAPGVKAES---PKRVVQAAPPAA 358
G S + + + G G Q GPGA APAP S PK QA P A
Sbjct: 932 FGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991
Query: 359 QTLAASGPASTAASMVIGPTMQGA----LPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSR 414
+++ A+ + P + A PPP + + + + L +
Sbjct: 992 KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEK 1051
Query: 415 TPTATTSGIRATLTPTVLAPRLPQPPQNPT---------NIQNFQLPPGMVLV------- 458
+P ++ L T L PP T N+ F P + +
Sbjct: 1052 SPKPEST---CPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLN 1108
Query: 459 ----RSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPP------VQISTVQA 508
R+ +GQL I + A +A P T + + T+ PP Q V+
Sbjct: 1109 CQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES--SSQKTAVPPQVKLVKKQEQEVKT 1166
Query: 509 PGTPIIARQVTPTTIIKQVSQAQTTVQ-----------PSATLQRSPGVQPQLVLGGAAQ 557
+I +V T ++++ TT Q SA ++ P + + ++ +
Sbjct: 1167 EAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEK 1226
Query: 558 TASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLAS---SGKQST 614
S ++ P T A T E K + L + +++A G+ +
Sbjct: 1227 IRSEEKKPLLEEKKP--TPEDKKLLPEAKTSAPEEQK--HDLLKSQVQIAEEKLEGRVAP 1282
Query: 615 ETAANVKE---LVQNLLDGKIEA----EDFTSRLYRELNSSPQPYLVPFLKRSLPALRQL 667
+T K+ ++ L G ++ +D T++ +E PQP + P +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKE---QPQPPCTAKPDQVEPGKEKT 1339
Query: 668 TPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQP 727
+ S QQP P + T ++ +SSS+ G+ + + + + + L +
Sbjct: 1340 EKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSL----GEIPSLIPTDEKDILKGLKKD 1395
Query: 728 TQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNP 787
+ P+ L + +++ TL QPH +++P
Sbjct: 1396 SFSQESSPSSPSDLA-KLESTVLSILEAQASTLADEKSEKKTQPH-----------EVSP 1443
Query: 788 LQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSE 847
QP K L T ++ + +Q+ + +F+ D D+ S
Sbjct: 1444 EQPKDQEKTQSLSETLEITISEEEIKESQEER-----KDTFKKDSQ-QDIPSSKDHKEKS 1497
Query: 848 ESARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVSYVSHATQ 907
E + T E ++ S + E P ++R +G D S +
Sbjct: 1498 EFVDDITTRREPYDSVEESSESEN--SPVPQRKRRTSVGSSSSDEYKQED-----SQGSG 1550
Query: 908 QRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDEQEREILM 967
+ + ++I E + ++ S +DD + +R QLK E E Q+K+E + + +
Sbjct: 1551 EEEDFIRKQIIEMSADEDASGSEDDEF-----IRNQLK--EISSSTESQKKEETKGKGKI 1603
Query: 968 RAAKSR 973
A K R
Sbjct: 1604 TAGKHR 1609
Score = 55.5 bits (132), Expect = 3e-07
Identities = 122/558 (21%), Positives = 185/558 (33%), Gaps = 81/558 (14%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRA---RPGGGGP------------QRPGPPSPR 111
PA G+ + + P A +PP G+ +PG P Q+PG SP
Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA 431
Query: 112 R-------PLVPAGPAPPAAKLRPPPEGSAGSCAPV--PAAAAVAAGPEPAPAGPAKPAG 162
+ P+ GP A+ P + SA P P+ A P P GPAKP
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP- 490
Query: 163 PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222
P + P PG P P PA P Q GS + +A P
Sbjct: 491 PQQPGSAKPPSQQPG-STKPPPQQPGPAKPSPQQP--GSTKPPSQQPGSAK--------P 539
Query: 223 AALLPLPKPAAPGTVIQTPPF--VGAAAP--PAPAAPSPPAAPAPAAPAAAPPPPPPAPA 278
+A P PA P T P G+ P P +PS P+ P P
Sbjct: 540 SA--QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL 597
Query: 279 TLARPPGHPAGPPTAAPAV--------PPP----------AAAQNGGSAGAAPAPAPAAG 320
L P T P P Q + G AP P++
Sbjct: 598 LLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP 657
Query: 321 GPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQ 380
P + +A + +P + SPK+ AAP Q L+ + +V PT+
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKK--DAAP--KQDLSKAPEPKKPPPLVKQPTLH 713
Query: 381 GALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPP 440
G+ + A PP A P +V + P A + P++ +P
Sbjct: 714 GSPSAKAKQPPEADSLSKPAPP-KEPSVPSEQDKAPVADDKPKQ---------PKMVKPT 763
Query: 441 QNPTNIQNFQLPPGM--VLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSA 498
+ + + P + V+S+ + P + + +Q+ ++P +
Sbjct: 764 TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823
Query: 499 PPVQISTVQAPGTPIIA---RQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGA 555
P + PG + +QV P ++ +AQT + P + P P G
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP--TPPGP 881
Query: 556 AQTASLGTATAVQTGTPQ 573
TA T Q+ PQ
Sbjct: 882 RPTAGQTVPTPQQSPKPQ 899
Score = 48.9 bits (115), Expect = 3e-05
Identities = 104/478 (21%), Positives = 160/478 (33%), Gaps = 59/478 (12%)
Query: 143 AAAVAAGPEPAPAGPAKPAG---PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLN 199
A+ + +G + PAKP ++L A P P P P P P P P P P +
Sbjct: 2373 ASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS 2432
Query: 200 GSAALLNSHH--AAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP 257
+L A+P + A + A PP P PS
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492
Query: 258 PAA-------PAPAAPAAAPPPPPPAPATLARPPGHPAGPPT---------------AAP 295
+ P P+ P AP P P T + P PT A
Sbjct: 2493 IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADY 2552
Query: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGV------SGQPGPGAAAAA------PAPGVK 343
+P P + + S ++P + + V G P +A+ A +P
Sbjct: 2553 KLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKD 2612
Query: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKG 403
S + V PP A P S+ + I GAL + +A P AP + P
Sbjct: 2613 LVSVEPVFSVVPPVT---AVEIPISSEQTFYIS----GALQTFSATPVTAPSSFQAAPTS 2665
Query: 404 AAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLP----PGMVLVR 459
+T +S+T + T ++ + ++ +P P NI + + P G + +
Sbjct: 2666 VTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNI-HLEKPQYKEDGKLQLV 2724
Query: 460 SENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVT 519
+ L +P+ + T R T QIS VQ P I
Sbjct: 2725 GDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQ----PSIINLSV 2780
Query: 520 PTTIIKQVSQAQTT---VQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQR 574
++I+ VS A T V +A+ + G + LV A T L T+ P R
Sbjct: 2781 TSSIVTPVSLATETVTFVTCTASASYTTGTE-SLVGAEHAMTTPLQLTTSKHAEPPYR 2837
Score = 30.4 bits (67), Expect = 9.5
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 8/82 (9%)
Query: 468 IPQQALAQMQAQAHAQPQTTMA-PRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQ 526
IP Q + Q P T PA PT AP + +QV+P
Sbjct: 3868 IPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPY----- 3922
Query: 527 VSQAQTTVQPSATLQRSPGVQP 548
Q Q T Q AT+ +P VQP
Sbjct: 3923 --QTQPTFQAVATMSFTPQVQP 3942
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 101 bits (252), Expect = 3e-21
Identities = 223/997 (22%), Positives = 346/997 (34%), Gaps = 181/997 (18%)
Query: 86 APEPPPAGRARPGGGGPQRPG----PPSPRRPLVPAGPAPPAAKLRP---------PPEG 132
+P PP + PG Q+PG P P +P PA P+ +P PP
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-----PAQPSGLTKPLAQQPGTVKPPVQ 354
Query: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPA----GPAALAARAGPGPGPGPGPGPGPGPGK 188
G+ P PA A P G KP+ GP ALA G G P PGP P +
Sbjct: 355 PPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413
Query: 189 PAG---PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245
G P A Q P P P T +Q P G
Sbjct: 414 QVGTPKPLAQQ-------------------------PGLQSPAKAPGPTKTPVQQP---G 445
Query: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQN 305
PA A P A PP P P A+PP P PA PPP
Sbjct: 446 PGKIPAQQA-GPGKTSAQQTGPTKPPSQLPGP---AKPP-----PQQPGPAKPPPQ---- 492
Query: 306 GGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG 365
G+A P+ G QPGP A +P + P + +A P+AQ + +
Sbjct: 493 --QPGSAKPPSQQPGSTKPPPQQPGP--AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
Query: 366 PASTAASMVIGPTMQGALPSPAAVPPPAPGTPT-GLPKGAAGA--VTQSLSRTPTATTSG 422
P++ ++ + T G P V P A P+ GLPK T+ L P
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 423 IRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQ----- 477
TV + P + T ++ + L + R+ G L +P +++
Sbjct: 609 TCTECQTTVCSLCGFNPNPHLTEVKEW-LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVT 667
Query: 478 -----AQAHAQPQTTMAPRPATPTSAPPVQISTVQAP-GTPIIARQVT----PTTIIKQV 527
+++ QPQ T + A AP +S P P + +Q T P+ KQ
Sbjct: 668 TTSAVSKSSPQPQQTSPKKDA----APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP 723
Query: 528 SQAQTTVQPSATLQRS-PGVQPQ-------------------LVLGGAAQTASLGTATAV 567
+A + +P+ + S P Q + LV +A T ++ V
Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
Query: 568 QTGTPQRTVPGATTTSSAATETMENV-KKCKNFLSTLI-KLASSGKQSTETAANVKELVQ 625
Q+ ++T P T S+ +++ +K F S I + AS K + + + Q
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ 843
Query: 626 NLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPP 685
+D + E+ + SP+P P K S P P + + QQ P P
Sbjct: 844 KQVDPVQKKEEPKK---AQTKMSPKPDAKPMPKGS-PTPPGPRPTAGQTVPTPQQSPKPQ 899
Query: 686 TSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQ 745
+L ++ + + TVT L S+ + GQP P
Sbjct: 900 EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP---HS 956
Query: 746 PPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKAL 805
PGA ++ Q P + P + Q P + +PV K P + L
Sbjct: 957 QSGPGAPMK--QAPAPSQPPTSQGPP------KSTGQAPPAPAKSIPVKKETKAPAAEKL 1008
Query: 806 SAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELVGTLTR 865
+ QA ++ + + + I D S+ +E +L T L +
Sbjct: 1009 EPKAEQAPTVKRTETE-------KKPPPIKDSKSLT----AEPQKAVLPTK------LEK 1051
Query: 866 SCKDETFLLQAPLQRRILEIGKK-----HGITELHPDVVSYVSHATQQRLQNLVEKISET 920
S K E+ PL + L IG K + TE V + L + E +
Sbjct: 1052 SPKPES---TCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLN 1108
Query: 921 AQ-QKNFSYKDDD---------------------RYEQASDVRAQLKFFEQLDQIEKQRK 958
Q Q+ S + D Q + V Q+K ++ +Q + K
Sbjct: 1109 CQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ---EVK 1165
Query: 959 DEQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQE 995
E E+ IL + ++ S ++ P + QK +E + ++
Sbjct: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK 1202
Score = 69.3 bits (168), Expect = 2e-11
Identities = 143/656 (21%), Positives = 216/656 (32%), Gaps = 116/656 (17%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
P V+ G + A GP P PG P PP + P PQ+
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG--PAKPPPQQPGPAKPPPQQ 493
Query: 105 PG---PPSPRRPLVPAGPAPPAAKLRP--PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK 159
PG PPS + P PP + P P GS P P+ +A P PAK
Sbjct: 494 PGSAKPPSQQ----PGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAK 548
Query: 160 PAGPAALAARAGPGPG-PGPGPGPGPGPGKPAGPGAAQTL----NGSAALLNSHHAA--- 211
P+ + + G G P P P +P G +T+ N + LL+ A
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 212 ------APAVSLVNNGPAALLP--------------------LPKPAAPGTVIQTPPFVG 245
SL P L P P++P ++T P
Sbjct: 609 TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTT 668
Query: 246 AAA----PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301
+A P P SP AP + P P P + +P H G P+A PP A
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH--GSPSAKAKQPPEA 726
Query: 302 AAQNGGSAGAAPA-PAPAAGGPAGVSGQPGPGAA------AAAPAPGVKAESPKRVVQA- 353
+ + + P+ P+ P P ++ + K + P VQ+
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
Query: 354 -----APPAAQTLAASGPASTAASMVIGPTMQGALPSPAA----VPPPAPGTPT------ 398
PP A + + P A+P PA+ + P P + +
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 399 ------GLPKGAAGAVTQSLSRTP----TATTSGIRATLTPTVLAPRLPQPPQNPTNIQN 448
PK A ++ P + T G R T TV P+ PQ + +
Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS--RR 904
Query: 449 FQLPPGMVL----------VRSENGQLLMIPQQALAQM--------QAQAHAQ--PQTTM 488
F L G + + G+L +Q Q H+Q P M
Sbjct: 905 FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPM 964
Query: 489 --APRPATPTSAPPVQISTVQAPGTPIIARQVTPTT------IIKQVSQAQTTVQPSATL 540
AP P+ P ++ ST QAP P + V T ++ ++ TV+ + T
Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 541 QRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKC 596
++ P ++ L Q A L T ++ P+ T P T + ++ N C
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLE-KSPKPESTCPLCKTELNIGSKDPPNFNTC 1079
Score = 63.9 bits (154), Expect = 8e-10
Identities = 164/759 (21%), Positives = 245/759 (32%), Gaps = 108/759 (14%)
Query: 91 PAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGP 150
P G A G G SP +PAG ++L S + A + A G
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQL------SEEERRQIAAVMSRAQGL 66
Query: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG-----------AAQTLN 199
PA P+ + P G P PG+PA PG + Q L
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
Query: 200 GSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA 259
G + S + L ++++ PG + + ++ P
Sbjct: 127 GRSPSTISLKESKSRTDLKEEHKSSMM-------PGFLSEVNALSAVSSVVNKFNPFDLI 179
Query: 260 APAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA 319
+ + A+ +P G P P P P G P
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPK------QQGPGRDPLQQD 233
Query: 320 GGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ---AAPPAAQTLAASGPASTAASMVIG 376
G P +S Q + P G + P + Q A P + AS P + A +V G
Sbjct: 234 GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRD--ASRPQTKQADIVRG 291
Query: 377 PTMQGALPSPAAVP--PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIR-------ATL 427
+++ +LPSP+ P P PG P G +Q P A SG+ T+
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPG--HEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349
Query: 428 TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTT 487
P V P +PP P P SE +ALAQ Q
Sbjct: 350 KPPVQPPGTTKPPAQPLG----PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-- 403
Query: 488 MAPRPATPTSAPPVQIST----VQAPGTPIIARQVTPT-TIIKQVSQAQTTVQPS----A 538
P PA P P Q+ T Q PG A+ PT T ++Q + Q +
Sbjct: 404 -QPGPAKP---PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 539 TLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKN 598
+ Q++ +P L G A+ A P PG+ S + + +
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPA----KPPPQQPGSAKPPSQQPGSTKPPPQQPG 515
Query: 599 FLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSP--QPYLVPF 656
+ S K ++ + K Q K A+ T + + + P P + P
Sbjct: 516 PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPS 575
Query: 657 LK----RSLP----------ALRQLTPDSAAFIQQSQQQPP-------PPTSQATTALTA 695
K + LP L P+ A F ++ Q P T
Sbjct: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635
Query: 696 VVLSSSVQRTAGKTAATVTSALQP-----PVL-------SLTQPTQVGVGKQGQPTPLVI 743
+ L+ ++R G A V S+ QP PV S QP Q K P +
Sbjct: 636 LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695
Query: 744 Q--QPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTP 780
+ +P KP L++ P TL +P +QP L+ P
Sbjct: 696 KAPEPKKPPPLVKQP--TLHGSPSAKAKQPPEADSLSKP 732
Score = 63.9 bits (154), Expect = 8e-10
Identities = 77/346 (22%), Positives = 117/346 (33%), Gaps = 49/346 (14%)
Query: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP--APAT 279
PA+ LP P+ + PF +++ A P PP P P P PPPPPP P T
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 280 LARPPGHP------AGPPT-------AAPAVPPPAAAQNGG---SAGAAPAPAPAAGGPA 323
+P P A P T A + A ++ G + AP P P+
Sbjct: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491
Query: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383
+ P P P +PK V+ P Q P T S+ T+
Sbjct: 2492 SI---PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548
Query: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
+ +P P T LS ++ +LT T + LP P P
Sbjct: 2549 SADYKLPSP----------------TSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTP 2592
Query: 444 TNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQI 503
T+ Q + L P + L ++ P T P + +
Sbjct: 2593 TDSSASQ---------AITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISG 2643
Query: 504 STVQAPGTPIIAR---QVTPTTIIKQVSQAQTTVQPSATLQRSPGV 546
+ TP+ A Q PT++ + ++ + + SAT +P V
Sbjct: 2644 ALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSV 2689
Score = 55.8 bits (133), Expect = 2e-07
Identities = 199/1026 (19%), Positives = 339/1026 (33%), Gaps = 170/1026 (16%)
Query: 57 ALGNHV--VSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPL 114
ALG + V SP P ++P+P + P P++P
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP- 703
Query: 115 VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP------------APAGPAKPAG 162
PP K +P GS + A P A + P P AP KP
Sbjct: 704 ------PPLVK-QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 163 PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG- 221
P + P P P+ +Q + L + +A P+ S G
Sbjct: 757 PKMVK----PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT-DSAKPSQSFPPTGE 811
Query: 222 ---PAALLPLPKPAAPGTVIQTP-------------PFVGAAAP---PAPAAPSPPAAPA 262
P +P+PA+ +I P P P +P P A P
Sbjct: 812 KVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPM 871
Query: 263 PAAPAAAPPPPPPAPATLARPPGHP------------AGPPTAAPAVPPPAAAQN----- 305
P P P P A T+ P P G T AP P +
Sbjct: 872 PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931
Query: 306 ---GGSAGAAPAPAPAAGGPAGVSGQPGPGA-AAAAPAPGVKAES---PKRVVQAAPPAA 358
G S + + + G G Q GPGA APAP S PK QA P A
Sbjct: 932 FGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991
Query: 359 QTLAASGPASTAASMVIGPTMQGA----LPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSR 414
+++ A+ + P + A PPP + + + + L +
Sbjct: 992 KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEK 1051
Query: 415 TPTATTSGIRATLTPTVLAPRLPQPPQNPT---------NIQNFQLPPGMVLV------- 458
+P ++ L T L PP T N+ F P + +
Sbjct: 1052 SPKPEST---CPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLN 1108
Query: 459 ----RSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPP------VQISTVQA 508
R+ +GQL I + A +A P T + + T+ PP Q V+
Sbjct: 1109 CQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES--SSQKTAVPPQVKLVKKQEQEVKT 1166
Query: 509 PGTPIIARQVTPTTIIKQVSQAQTTVQ-----------PSATLQRSPGVQPQLVLGGAAQ 557
+I +V T ++++ TT Q SA ++ P + + ++ +
Sbjct: 1167 EAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEK 1226
Query: 558 TASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLAS---SGKQST 614
S ++ P T A T E K + L + +++A G+ +
Sbjct: 1227 IRSEEKKPLLEEKKP--TPEDKKLLPEAKTSAPEEQK--HDLLKSQVQIAEEKLEGRVAP 1282
Query: 615 ETAANVKE---LVQNLLDGKIEA----EDFTSRLYRELNSSPQPYLVPFLKRSLPALRQL 667
+T K+ ++ L G ++ +D T++ +E PQP + P +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKE---QPQPPCTAKPDQVEPGKEKT 1339
Query: 668 TPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQP 727
+ S QQP P + T ++ +SSS+ G+ + + + + + L +
Sbjct: 1340 EKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSL----GEIPSLIPTDEKDILKGLKKD 1395
Query: 728 TQVGVGKQGQPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNP 787
+ P+ L + +++ TL QPH +++P
Sbjct: 1396 SFSQESSPSSPSDLA-KLESTVLSILEAQASTLADEKSEKKTQPH-----------EVSP 1443
Query: 788 LQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSE 847
QP K L T ++ + +Q+ + +F+ D D+ S
Sbjct: 1444 EQPKDQEKTQSLSETLEITISEEEIKESQEER-----KDTFKKDSQ-QDIPSSKDHKEKS 1497
Query: 848 ESARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVSYVSHATQ 907
E + T E ++ S + E P ++R +G D S +
Sbjct: 1498 EFVDDITTRREPYDSVEESSESEN--SPVPQRKRRTSVGSSSSDEYKQED-----SQGSG 1550
Query: 908 QRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDEQEREILM 967
+ + ++I E + ++ S +DD + +R QLK E E Q+K+E + + +
Sbjct: 1551 EEEDFIRKQIIEMSADEDASGSEDDEF-----IRNQLK--EISSSTESQKKEETKGKGKI 1603
Query: 968 RAAKSR 973
A K R
Sbjct: 1604 TAGKHR 1609
Score = 55.5 bits (132), Expect = 3e-07
Identities = 122/558 (21%), Positives = 185/558 (33%), Gaps = 81/558 (14%)
Query: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRA---RPGGGGP------------QRPGPPSPR 111
PA G+ + + P A +PP G+ +PG P Q+PG SP
Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA 431
Query: 112 R-------PLVPAGPAPPAAKLRPPPEGSAGSCAPV--PAAAAVAAGPEPAPAGPAKPAG 162
+ P+ GP A+ P + SA P P+ A P P GPAKP
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP- 490
Query: 163 PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222
P + P PG P P PA P Q GS + +A P
Sbjct: 491 PQQPGSAKPPSQQPG-STKPPPQQPGPAKPSPQQP--GSTKPPSQQPGSAK--------P 539
Query: 223 AALLPLPKPAAPGTVIQTPPF--VGAAAP--PAPAAPSPPAAPAPAAPAAAPPPPPPAPA 278
+A P PA P T P G+ P P +PS P+ P P
Sbjct: 540 SA--QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL 597
Query: 279 TLARPPGHPAGPPTAAPAV--------PPP----------AAAQNGGSAGAAPAPAPAAG 320
L P T P P Q + G AP P++
Sbjct: 598 LLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP 657
Query: 321 GPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQ 380
P + +A + +P + SPK+ AAP Q L+ + +V PT+
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKK--DAAP--KQDLSKAPEPKKPPPLVKQPTLH 713
Query: 381 GALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPP 440
G+ + A PP A P +V + P A + P++ +P
Sbjct: 714 GSPSAKAKQPPEADSLSKPAPP-KEPSVPSEQDKAPVADDKPKQ---------PKMVKPT 763
Query: 441 QNPTNIQNFQLPPGM--VLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSA 498
+ + + P + V+S+ + P + + +Q+ ++P +
Sbjct: 764 TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823
Query: 499 PPVQISTVQAPGTPIIA---RQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGA 555
P + PG + +QV P ++ +AQT + P + P P G
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP--TPPGP 881
Query: 556 AQTASLGTATAVQTGTPQ 573
TA T Q+ PQ
Sbjct: 882 RPTAGQTVPTPQQSPKPQ 899
Score = 48.9 bits (115), Expect = 3e-05
Identities = 104/478 (21%), Positives = 160/478 (33%), Gaps = 59/478 (12%)
Query: 143 AAAVAAGPEPAPAGPAKPAG---PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLN 199
A+ + +G + PAKP ++L A P P P P P P P P P P +
Sbjct: 2373 ASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS 2432
Query: 200 GSAALLNSHH--AAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP 257
+L A+P + A + A PP P PS
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492
Query: 258 PAA-------PAPAAPAAAPPPPPPAPATLARPPGHPAGPPT---------------AAP 295
+ P P+ P AP P P T + P PT A
Sbjct: 2493 IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADY 2552
Query: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGV------SGQPGPGAAAAA------PAPGVK 343
+P P + + S ++P + + V G P +A+ A +P
Sbjct: 2553 KLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKD 2612
Query: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKG 403
S + V PP A P S+ + I GAL + +A P AP + P
Sbjct: 2613 LVSVEPVFSVVPPVT---AVEIPISSEQTFYIS----GALQTFSATPVTAPSSFQAAPTS 2665
Query: 404 AAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLP----PGMVLVR 459
+T +S+T + T ++ + ++ +P P NI + + P G + +
Sbjct: 2666 VTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNI-HLEKPQYKEDGKLQLV 2724
Query: 460 SENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVT 519
+ L +P+ + T R T QIS VQ P I
Sbjct: 2725 GDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQ----PSIINLSV 2780
Query: 520 PTTIIKQVSQAQTT---VQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQR 574
++I+ VS A T V +A+ + G + LV A T L T+ P R
Sbjct: 2781 TSSIVTPVSLATETVTFVTCTASASYTTGTE-SLVGAEHAMTTPLQLTTSKHAEPPYR 2837
Score = 30.4 bits (67), Expect = 9.5
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 8/82 (9%)
Query: 468 IPQQALAQMQAQAHAQPQTTMA-PRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQ 526
IP Q + Q P T PA PT AP + +QV+P
Sbjct: 3868 IPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPY----- 3922
Query: 527 VSQAQTTVQPSATLQRSPGVQP 548
Q Q T Q AT+ +P VQP
Sbjct: 3923 --QTQPTFQAVATMSFTPQVQP 3942
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 101 bits (252), Expect = 3e-21
Identities = 94/325 (28%), Positives = 106/325 (32%), Gaps = 70/325 (21%)
Query: 66 SPAGAAG--AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA 123
SP+ AG GP+ P P PP + P GG + GPP P +P GP P
Sbjct: 28 SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP---QGPPPQG 84
Query: 124 AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP--- 180
K R P P P GP P P P P + P PG GP
Sbjct: 85 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ 144
Query: 181 -----GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG 235
P PGKP GP G P P P P
Sbjct: 145 GDKSRSPRSPPGKPQGPPP------------------------QGGNQPQGPPPPPGKP- 179
Query: 236 TVIQTPPFVGAAAPPAPAAPSPPAAPAP--------AAPAAAPPPPPP----APATLARP 283
Q PP G P P P P P P +P P PPP P P
Sbjct: 180 ---QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP 236
Query: 284 PGHPAGPPTAA---PAVPPPAA------AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334
PG P GPP P PPP AQ G + +A +P G P G Q G
Sbjct: 237 PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP---PGKPQGPPQQEGNNPQ 293
Query: 335 AAAPAPGVKAESPKRVVQAAPPAAQ 359
P G + P+ APPA Q
Sbjct: 294 GPPPPAGGNPQQPQ-----APPAGQ 313
Score = 95.1 bits (235), Expect = 3e-19
Identities = 83/281 (29%), Positives = 97/281 (34%), Gaps = 32/281 (11%)
Query: 65 GSPAGAAGAGPAAPAEGAPGAAPE-PPPAGRARPGGGGPQ--RPGPPSPRRPLVPAGPAP 121
G P G G + + +P P+ PPP G +P G P +P P P+ P GP P
Sbjct: 75 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134
Query: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA-GPGPGPGPGP 180
P PPP+G P P P G +P GP + GP P G P
Sbjct: 135 PGKPQGPPPQGDKSRSPRSPPGKPQG----PPPQGGNQPQGPPPPPGKPQGPPPQGGKKP 190
Query: 181 GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT 240
P PGKP GP G + + P G P P P P Q
Sbjct: 191 QGPPPPGKPQGPPP----QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP----QG 242
Query: 241 PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAA---PAV 297
PP G P P P P P P + PPG P GPP P
Sbjct: 243 PPPQGGNKPQGP--------PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 294
Query: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP 338
PPP A N AP AG P G P G + P
Sbjct: 295 PPPPAGGN-----PQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
Score = 84.3 bits (207), Expect = 6e-16
Identities = 96/361 (26%), Positives = 112/361 (31%), Gaps = 74/361 (20%)
Query: 146 VAAGPE-PAPAGPAKPAGPAALAARA-GPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAA 203
+A P+ P+P G KP GP + GP P G P P PGKP GP
Sbjct: 32 IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP--------- 82
Query: 204 LLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAP-SPPAAPA 262
G + P P P Q PP G P P P P P
Sbjct: 83 ----------------QGDKSRSPRSPPGKP----QGPPPQGGNQPQGPPPPPGKPQGPP 122
Query: 263 PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322
P PPPP P G + P + P P Q G P P GP
Sbjct: 123 PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 182
Query: 323 AGVSGQ-----PGPGAAAAAPAPGVK---AESPKRVVQAAPPAAQTLAASGPASTAASMV 374
G+ P PG P G K ++SP Q PP P
Sbjct: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ- 241
Query: 375 IGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAP 434
GP QG PP PG P G P G+ +QS +R+P G
Sbjct: 242 -GPPPQGGNKPQG---PPPPGKPQG-PPAQGGSKSQS-ARSPPGKPQG------------ 283
Query: 435 RLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPAT 494
PPQ N PP G PQQ A Q P+ RP+
Sbjct: 284 ----PPQQEGNNPQGPPPPA-------GGN----PQQPQAPPAGQPQGPPRPPQGGRPSR 328
Query: 495 P 495
P
Sbjct: 329 P 329
Score = 78.6 bits (192), Expect = 3e-14
Identities = 73/258 (28%), Positives = 90/258 (34%), Gaps = 46/258 (17%)
Query: 64 SGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRAR--PGGGGPQRPGPPSPRRPLVP----- 116
S SP G P +G PPP G+ + P GG + GPP P +P P
Sbjct: 87 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD 146
Query: 117 ---AGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP-------APAGPAKPAGPA-- 164
+ +PP PPP+G P P GP P P P KP GP
Sbjct: 147 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGGKKPQGPPPPGKPQGPPPQ 205
Query: 165 ---ALAARAGPGPGPGPGPGPGPGP-GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNN 220
+ ++++ PG GP P G P G P PG Q P N
Sbjct: 206 GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ--------------GPPPQG--GN 249
Query: 221 GPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATL 280
P P KP P P G+ + A + P P P PPPPA
Sbjct: 250 KPQGPPPPGKPQGP------PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 303
Query: 281 ARPPGHPAGPPTAAPAVP 298
+P PAG P P P
Sbjct: 304 QQPQAPPAGQPQGPPRPP 321
Score = 40.0 bits (92), Expect = 0.012
Identities = 28/93 (30%), Positives = 35/93 (37%), Gaps = 4/93 (4%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPP--PAGRARPGGGGP 102
P P + G + G P GP A +A PP P G + G P
Sbjct: 233 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP 292
Query: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG 135
Q P PP+ P P APPA + + PP G
Sbjct: 293 QGPPPPAGGNPQQPQ--APPAGQPQGPPRPPQG 323
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 101 bits (252), Expect = 3e-21
Identities = 93/301 (30%), Positives = 103/301 (34%), Gaps = 57/301 (18%)
Query: 62 VVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121
V+SG P G G P P PP RP GG Q GPP RP P GP P
Sbjct: 31 VISGKPEGRRPQGGNQPQR-----TPPPPGKPEGRPPQGGNQSQGPPP--RPGKPEGPPP 83
Query: 122 PAAKLR--PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPG 179
PPP P P + GP P P KP GP GP P PG
Sbjct: 84 QGGNQSQGPPPRPGKPEGQP-PQGGNQSQGPPPRPG---KPEGPPPQGGNQSQGPPPRPG 139
Query: 180 P-------------GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALL 226
GP P PGKP GP G+ + H P G +
Sbjct: 140 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQ---GGNQSQGPPPHPGKPEGPPPQGGNQSQG 196
Query: 227 PLPKPAAPGTVIQTPPFVGA----AAPPAPAAPSPPAAPAPAAPAAAPPPP------PPA 276
P P+P P + PP G PP P P P + P PP P PP
Sbjct: 197 PPPRPGKP----EGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQ 252
Query: 277 PATLAR---PPGHPAGPP----TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP-AGVSGQ 328
+ PPG P GPP +PPPA G P P P G P GQ
Sbjct: 253 EGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQG------PPPPPQGGRPHRPPQGQ 306
Query: 329 P 329
P
Sbjct: 307 P 307
Score = 85.5 bits (210), Expect = 2e-16
Identities = 85/291 (29%), Positives = 90/291 (30%), Gaps = 71/291 (24%)
Query: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR--ARPGGGGP 102
P PE R G S P G P +G + PP G+ +P GG
Sbjct: 54 PGKPEGRPPQGGNQ-----SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGN 108
Query: 103 QRPGPPSPRRPLVPAGPAP------------PAAKLRPPPEGSAGSCAPVPAAAAVAAGP 150
Q GPP RP P GP P P PPP+G S P P GP
Sbjct: 109 QSQGPPP--RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK-PEGP 165
Query: 151 EPA--------PAGPAKPAGPAALAARAGPGPGPGPGP-------------GPGPGPGKP 189
P P P KP GP GP P PG GP P PGKP
Sbjct: 166 PPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 225
Query: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
GP S N P P P P P Q PP P
Sbjct: 226 EGP----------------------PSQGGNKPQG--PPPHPGKP----QGPPPQEGNKP 257
Query: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP 300
P P P P P P PPPA PP G P P PP
Sbjct: 258 QRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308
Score = 64.3 bits (155), Expect = 6e-10
Identities = 83/289 (28%), Positives = 93/289 (32%), Gaps = 39/289 (13%)
Query: 227 PLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAA--PAAAPPPPPPAPATLARPP 284
P P PG PP G + P P P P P + PPP P P +PP
Sbjct: 47 PQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE--GQPP 104
Query: 285 ---GHPAGPP--TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA 339
GPP P PPP GG+ P P P G P G Q G + P
Sbjct: 105 QGGNQSQGPPPRPGKPEGPPP----QGGNQSQGPPPRP--GKPEGPPPQGGNQSQGPPPR 158
Query: 340 PGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTG 399
PG K E P PP + P GP QG S PPP PG P G
Sbjct: 159 PG-KPEGP-------PPQGGNQSQGPPPHPGKPE--GPPPQGGNQSQG--PPPRPGKPEG 206
Query: 400 LPKGAAGAVTQSLSRTP-----TATTSGIRATLTPTVLAPRLPQ-PPQNPTNIQNFQLPP 453
P G +Q P + G + P P PQ PP N PP
Sbjct: 207 -PPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPP--HPGKPQGPPPQEGNKPQRPPPP 263
Query: 454 GMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQ 502
G G PQQ L + P RP P P Q
Sbjct: 264 GRPQGPPPPGG---NPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ 309
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,476,172
Number of Sequences: 37866
Number of extensions: 4635409
Number of successful extensions: 178646
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2102
Number of HSP's successfully gapped in prelim test: 3141
Number of HSP's that attempted gapping in prelim test: 29584
Number of HSP's gapped (non-prelim): 50866
length of query: 1085
length of database: 18,247,518
effective HSP length: 113
effective length of query: 972
effective length of database: 13,968,660
effective search space: 13577537520
effective search space used: 13577537520
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.