Guide to the Human Genome
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Search of human proteins with 169172087

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169172087 PREDICTED: hypothetical protein [Homo sapiens]
         (278 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169172087 PREDICTED: hypothetical protein [Homo sapiens]           593   e-170
gi|113419362 PREDICTED: hypothetical protein [Homo sapiens]           442   e-124
gi|113418886 PREDICTED: hypothetical protein [Homo sapiens]           442   e-124
gi|113419893 PREDICTED: hypothetical protein [Homo sapiens]           442   e-124
gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]            48   1e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    47   2e-05
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            46   3e-05
gi|13376335 hypothetical protein LOC79946 [Homo sapiens]               45   7e-05
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       44   2e-04
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       44   2e-04
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             44   2e-04
gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]          44   2e-04
gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo ...    43   3e-04
gi|239757729 PREDICTED: hypothetical protein [Homo sapiens]            43   3e-04
gi|239752222 PREDICTED: hypothetical protein [Homo sapiens]            43   3e-04
gi|239746743 PREDICTED: hypothetical protein [Homo sapiens]            43   3e-04
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                43   3e-04
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 41   0.001
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    41   0.001
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    41   0.001
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             41   0.001
gi|42821110 hypothetical protein LOC340602 [Homo sapiens]              40   0.002
gi|118498339 EMI domain containing 2 [Homo sapiens]                    40   0.002
gi|239757749 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|239752259 PREDICTED: similar to hCG1981372 [Homo sapiens]           40   0.003
gi|239746772 PREDICTED: similar to hCG1981372 [Homo sapiens]           40   0.003
gi|154146199 sal-like 3 [Homo sapiens]                                 40   0.003
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    39   0.004
gi|169164483 PREDICTED: hypothetical protein [Homo sapiens]            39   0.004

>gi|169172087 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 278

 Score =  593 bits (1529), Expect = e-170
 Identities = 278/278 (100%), Positives = 278/278 (100%)

Query: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLK 60
           MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLK
Sbjct: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLK 60

Query: 61  LSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGE 120
           LSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGE
Sbjct: 61  LSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGE 120

Query: 121 WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL 180
           WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL
Sbjct: 121 WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL 180

Query: 181 SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG 240
           SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG
Sbjct: 181 SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG 240

Query: 241 EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR 278
           EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR
Sbjct: 241 EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR 278


>gi|113419362 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score =  442 bits (1137), Expect = e-124
 Identities = 223/278 (80%), Positives = 225/278 (80%), Gaps = 30/278 (10%)

Query: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLK 60
           MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAAL          GG  R +    
Sbjct: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALS---------GGPGRAA---- 47

Query: 61  LSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGE 120
                      G   GRG    P   P   P  R    +P      GCCAALAGGDTNGE
Sbjct: 48  -----------GSAIGRGAHLSPSRPPAAPPPRREVLSSP------GCCAALAGGDTNGE 90

Query: 121 WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL 180
           WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL
Sbjct: 91  WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL 150

Query: 181 SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG 240
           SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG
Sbjct: 151 SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG 210

Query: 241 EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR 278
           EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR
Sbjct: 211 EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR 248


>gi|113418886 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score =  442 bits (1137), Expect = e-124
 Identities = 223/278 (80%), Positives = 225/278 (80%), Gaps = 30/278 (10%)

Query: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLK 60
           MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAAL          GG  R +    
Sbjct: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALS---------GGPGRAA---- 47

Query: 61  LSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGE 120
                      G   GRG    P   P   P  R    +P      GCCAALAGGDTNGE
Sbjct: 48  -----------GSAIGRGAHLSPSRPPAAPPPRREVLSSP------GCCAALAGGDTNGE 90

Query: 121 WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL 180
           WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL
Sbjct: 91  WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL 150

Query: 181 SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG 240
           SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG
Sbjct: 151 SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG 210

Query: 241 EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR 278
           EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR
Sbjct: 211 EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR 248


>gi|113419893 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score =  442 bits (1137), Expect = e-124
 Identities = 223/278 (80%), Positives = 225/278 (80%), Gaps = 30/278 (10%)

Query: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLK 60
           MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAAL          GG  R +    
Sbjct: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALS---------GGPGRAA---- 47

Query: 61  LSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGE 120
                      G   GRG    P   P   P  R    +P      GCCAALAGGDTNGE
Sbjct: 48  -----------GSAIGRGAHLSPSRPPAAPPPRREVLSSP------GCCAALAGGDTNGE 90

Query: 121 WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL 180
           WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL
Sbjct: 91  WILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVL 150

Query: 181 SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG 240
           SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG
Sbjct: 151 SGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAG 210

Query: 241 EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR 278
           EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR
Sbjct: 211 EGFVPVAKALQVEPYLLWEGPAFSDSRRALCRLLAEKR 248


>gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 251

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 46/144 (31%), Positives = 55/144 (38%), Gaps = 28/144 (19%)

Query: 3   PAPPPCGPRPGPRSHKLPRECFPASG----------PGSPVLCAAALRRPRGGRCRRGGD 52
           P PP C PRP P   + P    PA+G          P  P L        R GR    G+
Sbjct: 39  PRPPLCAPRPAPGRAQSP---VPAAGAVPSPPAAAHPARPALRGETPAPGRRGRATTRGE 95

Query: 53  PRPSAHLKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQ------- 105
            +PS    LS     R  RG G GRG    P   P   P+ R P PAP G ++       
Sbjct: 96  VQPSVRPPLS----HRPLRGGGMGRGR---PGKGPPPNPSRRLP-PAPPGGRRTWLSALA 147

Query: 106 PGCCAALAGGDTNGEWILRGSTWG 129
            G  A  AG       + R + WG
Sbjct: 148 TGPAAGGAGRRRRSPPVFRAADWG 171



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 25/88 (28%), Positives = 30/88 (34%), Gaps = 29/88 (32%)

Query: 72  GPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGEWILRGSTWGLC 131
           G G+GR  RH  R      P  R PA   R P+ P                       LC
Sbjct: 14  GGGQGRH-RHSSRA-----PGTRTPATPARSPRPP-----------------------LC 44

Query: 132 PPSPGCGAGRRALATPGPLESPAAAQDP 159
            P P  G  +  +   G + SP AA  P
Sbjct: 45  APRPAPGRAQSPVPAAGAVPSPPAAAHP 72


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 49/158 (31%), Positives = 57/158 (36%), Gaps = 24/158 (15%)

Query: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLK 60
           +V   P      GP +   P E  P + P  P    A   RP GG  +R G P P   L 
Sbjct: 62  VVSGSPAGAAGAGPAA---PAEGAPGAAPEPP---PAGRARPGGGGPQRPGPPSPRRPLV 115

Query: 61  LSAASDWRAQ-RGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNG 119
            +  +   A+ R P EG      P   P     A  P PAP GP +P   AALA      
Sbjct: 116 PAGPAPPAAKLRPPPEGSAGSCAP--VPAAAAVAAGPEPAPAGPAKPAGPAALA------ 167

Query: 120 EWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQ 157
                        P PG G G      PG    P AAQ
Sbjct: 168 ---------ARAGPGPGPGPGPGPGPGPGKPAGPGAAQ 196



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 62/253 (24%), Positives = 74/253 (29%), Gaps = 78/253 (30%)

Query: 3   PAPPPCG---------PRPGPRSHKLPRECFPASGPGSPVLCAAALRRP---RGGRCR-- 48
           P PPP G          RPGP S   PR     +GP  P   AA LR P     G C   
Sbjct: 87  PEPPPAGRARPGGGGPQRPGPPS---PRRPLVPAGPAPP---AAKLRPPPEGSAGSCAPV 140

Query: 49  -------RGGDPRPSAHLKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPR 101
                   G +P P+   K +  +   A+ GPG G G                 P P P 
Sbjct: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG-------------PGPGPGPGPG 187

Query: 102 GPKQPGCCAALAGGDT----------------NGEWILRGS---------------TWGL 130
            P  PG    L G                   NG   L                      
Sbjct: 188 KPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAA 247

Query: 131 CPPSPGCGA-------GRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAARVLSGL 183
            PP+P   +          A A P P  +PA    P     GP     ++ P A   +G 
Sbjct: 248 APPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGG 307

Query: 184 LVGAGVGPRLPCG 196
             GA   P    G
Sbjct: 308 SAGAAPAPAPAAG 320


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 48/154 (31%), Positives = 60/154 (38%), Gaps = 26/154 (16%)

Query: 2   VPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAH--- 58
           +P PPP  PR G  S   PR   P +G  +P L       P   RCRR  +  P+ H   
Sbjct: 181 LPKPPPLQPRLGSASP--PRLAAPLAGSRAPSL------SPFPRRCRRRAERSPAGHGLP 232

Query: 59  --LKLSAASD---WRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALA 113
               LS   +    R +RG GE R +R   +G  +  P      P P GP  PG      
Sbjct: 233 LPRSLSRGGEVVGARRRRG-GEERRVRGRRQGCALGSP------PIPAGPAAPGRAGERR 285

Query: 114 GGDTNGEWILRGSTWGLCPPSPGCGAGRRALATP 147
                 +W  RG   G+ P     G G R   TP
Sbjct: 286 AA---RQWRKRGGGPGVSPREGAQGEGVRGGVTP 316



 Score = 28.1 bits (61), Expect = 8.8
 Identities = 42/150 (28%), Positives = 50/150 (33%), Gaps = 27/150 (18%)

Query: 85  GAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRAL 144
           G  V  P AR P P    P++P   A         EW   G+ W     +   G G   L
Sbjct: 32  GPAVCSPTARAPPPILPAPQRPPTRAR--------EW--EGAAWA----AGATGVGAALL 77

Query: 145 ATPG-------PLESPAAAQDPLPRHVGPSGLGWSLEPAARVLSGLLVGAGVGPRLPCGA 197
           A PG       PL    A+  P P      G     EP  R        +  G R    A
Sbjct: 78  ALPGSRRLGRVPLTFREASPGPAPGAPRARG-SCGREPGPR---RRRAPSSAGKRPAAAA 133

Query: 198 RWFHAPERPRCADLAALRGDGSALKTVVFP 227
           R   AP R R       R  GS ++  V P
Sbjct: 134 R--AAPPRQRSLARCLPRSVGSCVRPSVGP 161


>gi|13376335 hypothetical protein LOC79946 [Homo sapiens]
          Length = 257

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 55/170 (32%), Positives = 63/170 (37%), Gaps = 26/170 (15%)

Query: 7   PC----GPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRG-----GRCRRGGDPRPSA 57
           PC    G RP   S +  R C PA  P  P LC     RP       G C R    RP  
Sbjct: 46  PCMCTAGRRPNRASGRRRRSCSPA--PTWPPLCCYPQSRPTASAAGPGACMRASG-RPHG 102

Query: 58  HLKLSAASDWRAQ-RGPGEGRGLRHWPR--GAPVTVPAAR-----RPAPAPRGPKQPGCC 109
           +   S A     + R PG G  LR  PR    P   PA+R     RP   PR  ++    
Sbjct: 103 NTTASTAPPRHPRPRRPG-GPALRPTPRPCAGPAPPPASRDCRCRRPRRWPRAGRRGRRA 161

Query: 110 AALAGGDTNGEWILRGSTWGLCPPSPGCGA--GRRALATPGP-LESPAAA 156
            A         W  RG+   LC     C    G R   TP P   SP+AA
Sbjct: 162 GACKPSCAGAAWSARGAP--LCSYRTSCAGSCGARTAPTPAPTCASPSAA 209


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 54/187 (28%), Positives = 68/187 (36%), Gaps = 29/187 (15%)

Query: 3   PAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPR-------GGRCRRGGDPRP 55
           PA PP   RP P+         P  GPG         +RP         G     G P P
Sbjct: 452 PAGPPAQQRPPPQGGP------PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLP 505

Query: 56  SAHLKLSAASDWRAQRG--PGEGRGLRHWP-RGAPVTVPAARRPA-PAPR---GPKQP-- 106
                 ++A    A +   P +G+G +  P  G P   PAAR PA P+P+   GP Q   
Sbjct: 506 QRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATR 565

Query: 107 -----GCCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLP 161
                G     A G   G    +G      PP P     + + A P P   P   Q P P
Sbjct: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQK--PPGPAGPTRQASQAGPVPRTGPPTTQQPRP 623

Query: 162 RHVGPSG 168
              GP+G
Sbjct: 624 SGPGPAG 630


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 54/187 (28%), Positives = 68/187 (36%), Gaps = 29/187 (15%)

Query: 3   PAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPR-------GGRCRRGGDPRP 55
           PA PP   RP P+         P  GPG         +RP         G     G P P
Sbjct: 452 PAGPPAQQRPPPQGGP------PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLP 505

Query: 56  SAHLKLSAASDWRAQRG--PGEGRGLRHWP-RGAPVTVPAARRPA-PAPR---GPKQP-- 106
                 ++A    A +   P +G+G +  P  G P   PAAR PA P+P+   GP Q   
Sbjct: 506 QRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATR 565

Query: 107 -----GCCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLP 161
                G     A G   G    +G      PP P     + + A P P   P   Q P P
Sbjct: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQK--PPGPAGPTRQASQAGPVPRTGPPTTQQPRP 623

Query: 162 RHVGPSG 168
              GP+G
Sbjct: 624 SGPGPAG 630


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 81/285 (28%), Positives = 105/285 (36%), Gaps = 37/285 (12%)

Query: 3   PAPPPCGPRPGPRSHKLPRE------CFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPS 56
           P+PP   P PGP   K   E      C PA+     V+CA              GD  P 
Sbjct: 355 PSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPP 414

Query: 57  AHLKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARR--PAPAPRGPKQPGCCAALAG 114
                + +    A+ GP   R +       P  +P   +  P PAP  P++        G
Sbjct: 415 ETDPAATSEAPSARDGP--ERSVPKEAEPTPPVLPDEEKGPPGPAPE-PEREAETEPERG 471

Query: 115 GDTNGEWILRGSTWGLCP-PSP----GCGAGRRALATPGPLESP--AAAQDPLPRHVGPS 167
             T  E I  G+     P PSP     C   R A A+ GP  SP  AAA+ P P   GP 
Sbjct: 472 AGTEPERI--GTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESP-PVEPGPG 528

Query: 168 GLGWSLEPAARVLSGLLVGAGVGPRLPCGARWFHAPERPRCADLAALRG--DGSALKTVV 225
               SL+  A             P  P GA    APER      A LRG    S      
Sbjct: 529 ----SLDAEAAAPERPKAERAEAP--PAGAE-RAAPERKAERGGAELRGAKKFSVSSCRA 581

Query: 226 FPKPSLLSGLQGAAGEGFVPVAKALQVEPYLLWEGPAFSDSRRAL 270
            P+P +   L+ A+G   +P+A++  V     W   A  D  + L
Sbjct: 582 RPRPGVSRPLERASGR--LPLARSGPV-----WRSEAALDDLQGL 619



 Score = 29.3 bits (64), Expect = 4.0
 Identities = 49/187 (26%), Positives = 59/187 (31%), Gaps = 63/187 (33%)

Query: 6   PPCGPRPG--------PRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGD----- 52
           PP  P PG        P   K  R   P +G       A   +  RGG   RG       
Sbjct: 521 PPVEPGPGSLDAEAAAPERPKAERAEAPPAGAER---AAPERKAERGGAELRGAKKFSVS 577

Query: 53  -----PRPSAHLKLSAASD----------WRAQRGPGEGRGLRHWPRGAPVTVPAARRPA 97
                PRP     L  AS           WR++    + +GL           P   +P 
Sbjct: 578 SCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPE---------PQHAKPG 628

Query: 98  P---APRGPKQPGCCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPA 154
           P   A RGP+  G  AA   G                  SP     + A A PG  E   
Sbjct: 629 PRKLAERGPQDSGDRAASPAGPRK---------------SP-----QEAAAAPGTREPCP 668

Query: 155 AAQDPLP 161
           AAQ+P P
Sbjct: 669 AAQEPAP 675


>gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
          Length = 430

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/188 (30%), Positives = 70/188 (37%), Gaps = 22/188 (11%)

Query: 9   GPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLKLSA--ASD 66
           GPRPGP     P       G G P   A  L R   G       PR +A  +LSA  A  
Sbjct: 36  GPRPGPGDEAAPALGRRGKGSGGPEAGADGLSRGERG-------PRRAAVPELSAQPAGS 88

Query: 67  WRAQRGPGEGRGLRHWPRGAPVTV--------PAARRPAPAPRGPKQPGCCAALAGGDTN 118
            RA     +G G     R + +++        P + R  P P GP  P   +A +   + 
Sbjct: 89  PRASLAGSDGGGGGGSARSSGISLGYDQRHGSPRSGRSDPRP-GPGPPSVGSARSSVSSL 147

Query: 119 GEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLP--RHVGPSGLGWSLEPA 176
           G     G+     PP   C A  R+    GP   P  A  PLP  R  GPS     LE  
Sbjct: 148 GSRGSAGAYADFLPPG-ACPAPARSPEPAGPAPFPLPAL-PLPPGREGGPSAAERRLEAL 205

Query: 177 ARVLSGLL 184
            R L   L
Sbjct: 206 TRELERAL 213


>gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo
           sapiens]
          Length = 398

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 63/217 (29%), Positives = 73/217 (33%), Gaps = 39/217 (17%)

Query: 12  PGPRSHKLPRECFPASGPGSPVLCAAA------LRRPRGGRCRRGGDPRPSAHLKLSAAS 65
           P PRS   P     A GPG+P  C  +         P G + R+     P        A 
Sbjct: 37  PTPRSRVSPGVTSLAVGPGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAG 96

Query: 66  DWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAP----RG-PKQPGCCAALAGGDTNGE 120
             R  R P E   LR    G P      R    AP    RG PK P   +  +GG  +G 
Sbjct: 97  VGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSG- 155

Query: 121 WILRGSTWGLCPPSPGCG---------AGRRALATPGPLESPAAAQDP-LPRHVGPSGLG 170
               G          G G           R   A PGPL  PA    P  PR   P    
Sbjct: 156 ---AGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRPRTPP--- 209

Query: 171 WSLEPAARVLSGLLVGAGVGPRLP-CGARWFHAPERP 206
            + EP +R L          P LP C +RW  AP  P
Sbjct: 210 -TCEPPSRKLP---------PPLPLCRSRWVLAPPPP 236


>gi|239757729 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 329

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 43/121 (35%), Positives = 46/121 (38%), Gaps = 26/121 (21%)

Query: 6   PPCGPRPGPRSHKLPRECFPASGPGS-------PVLCAAALRRPRGGRCRRGGDPRPSAH 58
           PPC PR G R       C PA GP +       P        RP G RC  G    P+  
Sbjct: 73  PPCSPRRGRRGRPTQEVC-PAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPAL- 130

Query: 59  LKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRG----PKQPGCCAALAG 114
             L A     A+R P        WPR  PV   A RR  P P G    PKQ    AAL  
Sbjct: 131 --LGAP----ARRPPAHIPAQPRWPRLQPV---AKRRARPVPPGLPGAPKQ----AALTP 177

Query: 115 G 115
           G
Sbjct: 178 G 178


>gi|239752222 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 329

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 43/121 (35%), Positives = 46/121 (38%), Gaps = 26/121 (21%)

Query: 6   PPCGPRPGPRSHKLPRECFPASGPGS-------PVLCAAALRRPRGGRCRRGGDPRPSAH 58
           PPC PR G R       C PA GP +       P        RP G RC  G    P+  
Sbjct: 73  PPCSPRRGRRGRPTQEVC-PAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPAL- 130

Query: 59  LKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRG----PKQPGCCAALAG 114
             L A     A+R P        WPR  PV   A RR  P P G    PKQ    AAL  
Sbjct: 131 --LGAP----ARRPPAHIPAQPRWPRLQPV---AKRRARPVPPGLPGAPKQ----AALTP 177

Query: 115 G 115
           G
Sbjct: 178 G 178


>gi|239746743 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 329

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 43/121 (35%), Positives = 46/121 (38%), Gaps = 26/121 (21%)

Query: 6   PPCGPRPGPRSHKLPRECFPASGPGS-------PVLCAAALRRPRGGRCRRGGDPRPSAH 58
           PPC PR G R       C PA GP +       P        RP G RC  G    P+  
Sbjct: 73  PPCSPRRGRRGRPTQEVC-PAPGPCAQPAGTCPPPPTGEKQPRPHGFRCSHGSKRAPAL- 130

Query: 59  LKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRG----PKQPGCCAALAG 114
             L A     A+R P        WPR  PV   A RR  P P G    PKQ    AAL  
Sbjct: 131 --LGAP----ARRPPAHIPAQPRWPRLQPV---AKRRARPVPPGLPGAPKQ----AALTP 177

Query: 115 G 115
           G
Sbjct: 178 G 178


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 56/201 (27%), Positives = 77/201 (38%), Gaps = 27/201 (13%)

Query: 3   PAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLKLS 62
           P PPP G      S  LP     A+GP  P++ AA   +P+G     GG   P  ++ L+
Sbjct: 276 PPPPPVGGAVAQSSAPLPPFPGAATGP-QPMMAAAQPSQPQGAG--PGGQTLPPTNVTLA 332

Query: 63  A-ASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPA----PAPRGPKQPGCCAALAGGDT 117
             A     Q GP  G              PAA++P     P P+ P  PG    L    +
Sbjct: 333 QPAMSLPPQPGPAVG-------------APAAQQPQQFAYPQPQIP--PG--HLLPVQPS 375

Query: 118 NGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAA 177
                L+    GL PPSP   +   A A+P    +           VG   +G S +P+ 
Sbjct: 376 GQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSE 435

Query: 178 RVL--SGLLVGAGVGPRLPCG 196
            +   +G   G  V P  P G
Sbjct: 436 AMAPRTGPAQGGQVAPCQPTG 456


>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 54/179 (30%), Positives = 62/179 (34%), Gaps = 47/179 (26%)

Query: 3   PAPPPC-------------GPRPG-----PRSHKLPRECFPASGPGSPVLCAAALRRPRG 44
           PA PPC              P PG     P   +       AS  G+  + A  L  P G
Sbjct: 100 PAGPPCRAPGRGRAAATRRSPAPGTARGSPAGVERAGGATAASSAGTRSVPARRLPPPCG 159

Query: 45  GRCRRGGD---PRP-SAHLKLSAASD--WRAQRGPGEGR--GLRHWPRGAPVTVPAARRP 96
           G     G     RP SA L  S +S   W A  GPG  R      WP G  V  P A   
Sbjct: 160 GTSLGAGSRALRRPGSAALPRSPSSSRRWAAMPGPGAPRPGAPGTWPVGFAVAAPPAAAA 219

Query: 97  APAPRGPKQPGCCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAA 155
           + AP  P   G  AA   G     W+          P PGC        TPG   +PA+
Sbjct: 220 SVAPPPPAVAGAPAAAFRG-----WV--------AAPDPGC--------TPGTENAPAS 257



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 62/217 (28%), Positives = 69/217 (31%), Gaps = 34/217 (15%)

Query: 4   APPPCGPRPGPRSHKLPRE----CFPASGP--GSPVLCAAALRR---PRGGRCRRGGDPR 54
           +PP   P     S + P      CFPA     G P   + A  R   P G  CR  G  R
Sbjct: 53  SPPTVAPAASAGSQEHPGAGGPLCFPARSAAWGPPARASRAAGRRAGPAGPPCRAPGRGR 112

Query: 55  PSAHLKLSAASDWRAQRGPGEGRGLR---HWPRGAPVTVPAARRPAPAPRGPKQPGCCAA 111
            +A          R    PG  RG         GA     A  R  PA R P  P C   
Sbjct: 113 AAAT---------RRSPAPGTARGSPAGVERAGGATAASSAGTRSVPARRLP--PPCGGT 161

Query: 112 LAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGW 171
             G    G   LR       P SP   + RR  A PGP      A  P      P G   
Sbjct: 162 SLGA---GSRALRRPGSAALPRSP--SSSRRWAAMPGP-----GAPRPGAPGTWPVGFAV 211

Query: 172 SLEPAARVLSGLLVGAGVGPRLPCGARWFHAPERPRC 208
           +  PAA         A  G        W  AP+ P C
Sbjct: 212 AAPPAAAASVAPPPPAVAGAPAAAFRGWVAAPD-PGC 247


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 47/160 (29%), Positives = 52/160 (32%), Gaps = 31/160 (19%)

Query: 2   VPAPPPCGPRPGP--RSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHL 59
           +P PPP GP P P  R    P    P   PG+P        RP G    RG  PR     
Sbjct: 407 MPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP-----PFLRPPGMPGLRGPLPR----- 456

Query: 60  KLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNG 119
                       GP  GR     P G P   P    P P PRGP       A  G     
Sbjct: 457 --------LLPPGPPPGR-----PPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPR 503

Query: 120 EWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDP 159
             ++R       P  P  G     L  P PL +P     P
Sbjct: 504 PGMMRP------PLVPPLGPAPPGLFPPAPLPNPGVLSAP 537


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 75/258 (29%), Positives = 91/258 (35%), Gaps = 38/258 (14%)

Query: 5    PPPCGPRPGPRSHKLPRECFPASGP----GSPVLCAAALRRPRGGRCRRG--GDPRPSAH 58
            P P GP PGP     P+     SGP    G P      L+ P G    +G  GD  PS  
Sbjct: 914  PGPPGP-PGPSGKDGPKGARGDSGPPGRAGEP-----GLQGPAGPPGEKGEPGDDGPSGA 967

Query: 59   LKLSAASDWRAQRG----PGEGRGLRHWPRGAPVTVPAARRPAPAP---RGPKQPGCCAA 111
                       QRG    PG+ RG R +P     +    ++ AP     RGP  P     
Sbjct: 968  EGPPGPQGLAGQRGIVGLPGQ-RGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 1026

Query: 112  LAGGDTNGEWILRGSTWGLCPPSPGCGAGRRA-LATPGPLESPAAAQDP-LPRHVGPSGL 169
            L G    GE    GS     PP     AG +      G + +P A   P  P   GP+G 
Sbjct: 1027 LTG--PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGK 1084

Query: 170  GWSLEPAARVLSGLLVGAGVGPRLPCGARWFHAPERPRCADLAA-------LRGDGSALK 222
                  A            +GP  P GAR    P+ PR     A       L+G      
Sbjct: 1085 QGDRGEAG-------AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1137

Query: 223  TVVFPKPSLLSGLQGAAG 240
                P P   SG QGA+G
Sbjct: 1138 LQGLPGPPGPSGDQGASG 1155



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 81/303 (26%), Positives = 96/303 (31%), Gaps = 73/303 (24%)

Query: 5   PPPCGPRPGPRSHKLPRECFPASGPGSPVLCAA-------ALRRPRGGRCRRG-----GD 52
           P P GP PGP          PA GPG P    A         R P G +  RG     G 
Sbjct: 350 PGPAGP-PGPVG--------PAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 400

Query: 53  PRPSAHLKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPK----QPGC 108
           P P+              +G     G+   P       P   + A  P GPK    +PG 
Sbjct: 401 PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460

Query: 109 CAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRA----------LATPGPLESPA---- 154
                     GE    G       P P    G+R           +  PG   +P     
Sbjct: 461 AGFKGEQGPKGE---PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517

Query: 155 AAQDPL------PRHVGPSGL-------------GWSLEPAARVLSGLLVGAG----VGP 191
             QD L      P   GPSGL             G    P AR L+G    AG    VGP
Sbjct: 518 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 577

Query: 192 RLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAGEGFVPVAKALQ 251
               G      P  P+ A     RG    +    FP P   +G  G AGE  +P A  L+
Sbjct: 578 SGAPGEDGRPGPPGPQGA-----RGQPGVMG---FPGPKGANGEPGKAGEKGLPGAPGLR 629

Query: 252 VEP 254
             P
Sbjct: 630 GLP 632


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 75/258 (29%), Positives = 91/258 (35%), Gaps = 38/258 (14%)

Query: 5    PPPCGPRPGPRSHKLPRECFPASGP----GSPVLCAAALRRPRGGRCRRG--GDPRPSAH 58
            P P GP PGP     P+     SGP    G P      L+ P G    +G  GD  PS  
Sbjct: 845  PGPPGP-PGPSGKDGPKGARGDSGPPGRAGEP-----GLQGPAGPPGEKGEPGDDGPSGA 898

Query: 59   LKLSAASDWRAQRG----PGEGRGLRHWPRGAPVTVPAARRPAPAP---RGPKQPGCCAA 111
                       QRG    PG+ RG R +P     +    ++ AP     RGP  P     
Sbjct: 899  EGPPGPQGLAGQRGIVGLPGQ-RGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 957

Query: 112  LAGGDTNGEWILRGSTWGLCPPSPGCGAGRRA-LATPGPLESPAAAQDP-LPRHVGPSGL 169
            L G    GE    GS     PP     AG +      G + +P A   P  P   GP+G 
Sbjct: 958  LTG--PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGK 1015

Query: 170  GWSLEPAARVLSGLLVGAGVGPRLPCGARWFHAPERPRCADLAA-------LRGDGSALK 222
                  A            +GP  P GAR    P+ PR     A       L+G      
Sbjct: 1016 QGDRGEAG-------AQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1068

Query: 223  TVVFPKPSLLSGLQGAAG 240
                P P   SG QGA+G
Sbjct: 1069 LQGLPGPPGPSGDQGASG 1086



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 81/303 (26%), Positives = 96/303 (31%), Gaps = 73/303 (24%)

Query: 5   PPPCGPRPGPRSHKLPRECFPASGPGSPVLCAA-------ALRRPRGGRCRRG-----GD 52
           P P GP PGP          PA GPG P    A         R P G +  RG     G 
Sbjct: 281 PGPAGP-PGPVG--------PAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 331

Query: 53  PRPSAHLKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPK----QPGC 108
           P P+              +G     G+   P       P   + A  P GPK    +PG 
Sbjct: 332 PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 391

Query: 109 CAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRA----------LATPGPLESPA---- 154
                     GE    G       P P    G+R           +  PG   +P     
Sbjct: 392 AGFKGEQGPKGE---PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 448

Query: 155 AAQDPL------PRHVGPSGL-------------GWSLEPAARVLSGLLVGAG----VGP 191
             QD L      P   GPSGL             G    P AR L+G    AG    VGP
Sbjct: 449 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 508

Query: 192 RLPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAGEGFVPVAKALQ 251
               G      P  P+ A     RG    +    FP P   +G  G AGE  +P A  L+
Sbjct: 509 SGAPGEDGRPGPPGPQGA-----RGQPGVMG---FPGPKGANGEPGKAGEKGLPGAPGLR 560

Query: 252 VEP 254
             P
Sbjct: 561 GLP 563


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 41/143 (28%), Positives = 51/143 (35%), Gaps = 25/143 (17%)

Query: 96  PAPAPRGPKQPGCCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAA 155
           P P PRGP  PG      GG         G +  L PP PG G        P P   P++
Sbjct: 352 PPPTPRGPPPPG-----RGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSS 406

Query: 156 AQDPLPRHVGPSGLGWSLEPAARVLSGLLVGAGVGPRLPCGARWFHAPERPRCADLAALR 215
              P P  + P     +L PA     GL  G G G  L    +     + P   + +AL+
Sbjct: 407 GNGPAPPPLPP-----ALVPA----GGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQ 457

Query: 216 GDGSALKTVVFPKPSLLSGLQGA 238
                      P P    GL GA
Sbjct: 458 -----------PPPQSSEGLVGA 469


>gi|42821110 hypothetical protein LOC340602 [Homo sapiens]
          Length = 503

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 47/168 (27%), Positives = 58/168 (34%), Gaps = 20/168 (11%)

Query: 8   CGPRPGPR-----SHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLKLS 62
           C  +PGP      +H  P    P S PG     A   R    G  RRG D  P    +  
Sbjct: 238 CTAQPGPAFPHRATHLDPARLSPESAPGP----ARRGRASVPGPARRGCDSAPGPARRGR 293

Query: 63  AASDWRAQRG----PGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTN 118
            ++   A RG    PG  R  R    G  + V  AR  A        PG           
Sbjct: 294 DSAPVSAPRGRDSAPGSARRGRDSAPGPALRVRTARSDAGHRSTSTTPGTGLRSRSTQQR 353

Query: 119 GEWILRGSTWGLCPPSPGCGAGRRALA------TPGPLESPAAAQDPL 160
              + R S  G    +P CG G   LA      +P P E P+ A  P+
Sbjct: 354 SALLSRRSLSGSADENPSCGTGSERLAFQSRSGSPDP-EVPSRASPPV 400


>gi|118498339 EMI domain containing 2 [Homo sapiens]
          Length = 439

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 66/211 (31%), Positives = 78/211 (36%), Gaps = 47/211 (22%)

Query: 90  VPAARRPA-----PAPRGPKQPGCCAALAG--GDTNGEWILRGSTWGLCPPSPGCGAGRR 142
           VP  RRP      P   GP  P       G  G T GE    G    L PP P    G  
Sbjct: 189 VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQT-GEKGPAGPPGLLGPPGPRGLPGE- 246

Query: 143 ALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPA-------ARVLSGLL--VGAGV-GPR 192
            +  PGP   P  A +P P    P G  +SL+P        +R+ S ++  V AGV GPR
Sbjct: 247 -MGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305

Query: 193 LPCGARWFHAPERPRCADLAALRGDGSALKTVVFPKPSLLSGLQGAAGE-GFV-----PV 246
            P G      P  P                    P P    G QG AGE G V     P 
Sbjct: 306 GPPGPPGPPGPRGP--------------------PGPPGTPGSQGLAGERGTVGPSGEPG 345

Query: 247 AKALQVEPYLLWEGPAFSDSRRALCRLLAEK 277
            K  + E     EG      R AL ++LAE+
Sbjct: 346 VKGEEGEKAATAEGEGVQQLREAL-KILAER 375


>gi|239757749 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 264

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 47/180 (26%), Positives = 60/180 (33%), Gaps = 33/180 (18%)

Query: 5   PPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPR-PSAHLKLSA 63
           P     R G R+   P    P  G   P L  A   R  GGR R  G+ + P   L+  A
Sbjct: 16  PTDAEKRGGARAKATPPAPRPRPGGFRPPLQRARCYRAAGGRGRETGNAQGPRLALQARA 75

Query: 64  ASDWRAQRGPGEGRGLRHWPRGAPVTVPAA----------------RRPAPAPRGPKQPG 107
           A    A   P   R     PRG  + +P A                R+P PA R P+   
Sbjct: 76  A----APAFPAASRRSVPAPRGRRLLLPGAVAACAVSDGQPLSPPLRQPRPAARAPEGAL 131

Query: 108 CCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPS 167
               L  G            W   PP     A   ++    P    A+A+  LP   GP+
Sbjct: 132 ASCGLRAG------------WAGWPPQAAWRAWGASVDAAAPPSEAASAEARLPERSGPA 179


>gi|239752259 PREDICTED: similar to hCG1981372 [Homo sapiens]
          Length = 317

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 47/180 (26%), Positives = 60/180 (33%), Gaps = 33/180 (18%)

Query: 5   PPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPR-PSAHLKLSA 63
           P     R G R+   P    P  G   P L  A   R  GGR R  G+ + P   L+  A
Sbjct: 10  PTDAEKRGGARAKATPPAPRPRPGGFRPPLQRARCYRAAGGRGRETGNAQGPRLALQARA 69

Query: 64  ASDWRAQRGPGEGRGLRHWPRGAPVTVPAA----------------RRPAPAPRGPKQPG 107
           A    A   P   R     PRG  + +P A                R+P PA R P+   
Sbjct: 70  A----APAFPAASRRSVPAPRGRRLLLPGAVAACAVSDGQPLSPPLRQPRPAARAPEGAL 125

Query: 108 CCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPS 167
               L  G            W   PP     A   ++    P    A+A+  LP   GP+
Sbjct: 126 ASCGLRAG------------WAGWPPQAAWRAWGASVDAAAPPSEAASAEARLPERSGPA 173


>gi|239746772 PREDICTED: similar to hCG1981372 [Homo sapiens]
          Length = 317

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 47/180 (26%), Positives = 60/180 (33%), Gaps = 33/180 (18%)

Query: 5   PPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPR-PSAHLKLSA 63
           P     R G R+   P    P  G   P L  A   R  GGR R  G+ + P   L+  A
Sbjct: 10  PTDAEKRGGARAKATPPAPRPRPGGFRPPLQRARCYRAAGGRGRETGNAQGPRLALQARA 69

Query: 64  ASDWRAQRGPGEGRGLRHWPRGAPVTVPAA----------------RRPAPAPRGPKQPG 107
           A    A   P   R     PRG  + +P A                R+P PA R P+   
Sbjct: 70  A----APAFPAASRRSVPAPRGRRLLLPGAVAACAVSDGQPLSPPLRQPRPAARAPEGAL 125

Query: 108 CCAALAGGDTNGEWILRGSTWGLCPPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPS 167
               L  G            W   PP     A   ++    P    A+A+  LP   GP+
Sbjct: 126 ASCGLRAG------------WAGWPPQAAWRAWGASVDAAAPPSEAASAEARLPERSGPA 173


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 55/179 (30%), Positives = 60/179 (33%), Gaps = 53/179 (29%)

Query: 3   PAPPPCGPRPGPR----------SHKLPRECFPASGPGSPVLCAAA--LRRPRGGRCRRG 50
           PA  P  P P P           S   P      SGP +P     A  L RP  G    G
Sbjct: 244 PAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPG 303

Query: 51  GDPRPSAHLKLSAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRG-----PKQ 105
           G   PSA    SAA                          PAA  PAPAP+      P+ 
Sbjct: 304 GPAEPSAPAAPSAA------------------------PAPAAPAPAPAPQSAASSQPQS 339

Query: 106 PGCCAALAGGDTNGEWILRGSTWGLCPPSPGC-GAGRRALATPGPLESPAA---AQDPL 160
                ALA G       L G+  GL  PSP         +  P PL S AA   A DPL
Sbjct: 340 ASTPPALAPGS------LLGAAPGL--PSPLLPQTSASGVIFPNPLVSIAATANALDPL 390



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 58/221 (26%), Positives = 72/221 (32%), Gaps = 30/221 (13%)

Query: 3   PAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALR---RPRGGRCRRGGDPRPSAHL 59
           P PPP  P P   ++  P          S  +  A      R  GG    GG    +  L
Sbjct: 145 PRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPL 204

Query: 60  KLSAASDWRAQR--------GPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGC--- 108
            L      + Q+               L   P   P   PAA   AP P   + PG    
Sbjct: 205 ILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAAL 264

Query: 109 -------CAALAGGDTNGEWILRGSTWGLCPPS----PGCGAGRRALATPGPLESPAA-A 156
                   AA+AG          G+     P S    PG  A   A A P    +PAA A
Sbjct: 265 PLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPA 324

Query: 157 QDPLPRHVGPSGLGWSLEPAARVLSGLLVGAGVG---PRLP 194
             P P+    S    +  P A +  G L+GA  G   P LP
Sbjct: 325 PAPAPQSAASSQPQSASTPPA-LAPGSLLGAAPGLPSPLLP 364


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 37/122 (30%), Positives = 46/122 (37%), Gaps = 10/122 (8%)

Query: 3   PAPPPCGPRPGPRSHKLPRECFP--ASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLK 60
           PAPPP GP P P  H    E  P  A+  G P        R R   C R G P  ++  K
Sbjct: 41  PAPPP-GPGPAPPQHPPRAEALPPEAADEGGP----RGRLRSRDSSCGRPGTPGAASTAK 95

Query: 61  LSAASD---WRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDT 117
            S   +      Q  P    G    P+ +     AA  PAP P   ++ G   A   G+ 
Sbjct: 96  GSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAGPAGEP 155

Query: 118 NG 119
            G
Sbjct: 156 RG 157



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 43/130 (33%), Positives = 49/130 (37%), Gaps = 19/130 (14%)

Query: 1   MVPAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGG--RCRRGGDPRPSAH 58
           +V  PPP GP P   S   P    PAS PG+P    A    P GG       G   P+  
Sbjct: 757 LVRRPPP-GPAPAAASPGPPP---PASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARR 812

Query: 59  LK-----LSAASDWRAQRGPGEGRGLR----HWPRGAPVTVPAARRPAPAP--RGPKQPG 107
           L      LSA+        PG     R      PR  P   PAAR  AP+P  R    PG
Sbjct: 813 LSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRLGP--TPAARAAAPSPDRRDSASPG 870

Query: 108 CCAALAGGDT 117
               L   D+
Sbjct: 871 AAGGLDPQDS 880



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 40/157 (25%), Positives = 48/157 (30%), Gaps = 17/157 (10%)

Query: 3   PAP-PPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLKL 61
           PAP PP  P P P   + P    PA  PG      A  + P            P A    
Sbjct: 18  PAPGPPPPPPPAPPQQQPPPPPPPAPPPGPG---PAPPQHP------------PRAEALP 62

Query: 62  SAASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGPKQPGCCAALAGGDTNGEW 121
             A+D    RG    R       G P     A+       G  +P C  A   G   G  
Sbjct: 63  PEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPK 122

Query: 122 ILRGSTWGLCPPSPGCGAGRRA-LATPGPLESPAAAQ 157
           +          P+PG G    A     GP   P  +Q
Sbjct: 123 VSFSCRGAASGPAPGPGPAEEAGSEEAGPAGEPRGSQ 159


>gi|169164483 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 324

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 55/177 (31%), Positives = 61/177 (34%), Gaps = 52/177 (29%)

Query: 3   PAPPPCGPRPGPRSHKLPRECFPASGPGSPVLCAAALRRPRGGRCRRGGDPRPSAHLKLS 62
           P  PP G   GP      +   P              RRPRG    RGG  RP    + +
Sbjct: 146 PGLPPRGKASGPARDSAQQRRRPT-------------RRPRG---TRGGARRPGVRGQGA 189

Query: 63  AASDWRAQRGPGEGRGLRHWPRGAPVTVPAARRPAPAPRGP-KQPGCCAALAGGDTNGEW 121
           AA       GP   R     P GAP   P+ R P P PR P + P               
Sbjct: 190 AAV------GPTGPR-----PTGAP---PSRRTPPPGPRRPLRSPH-------------- 221

Query: 122 ILRGSTWGLC-PPSPGCGAGRRALATPGPLESPAAAQDPLPRHVGPSGLGWSLEPAA 177
              GS W    PPSP  GA   AL  P    S   A  PL       GL W+ E  A
Sbjct: 222 --SGSGWTPARPPSPPAGA-PEALRPPA---STTRAPAPLTLSFSARGLAWAGESPA 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.140    0.475 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,894,259
Number of Sequences: 37866
Number of extensions: 1220201
Number of successful extensions: 7668
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 696
Number of HSP's that attempted gapping in prelim test: 6498
Number of HSP's gapped (non-prelim): 1643
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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