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Search of human proteins with 168229150
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 728 0.0
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 560 e-160
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 560 e-160
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 560 e-160
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 546 e-155
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 511 e-145
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 489 e-138
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 451 e-127
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 258 8e-69
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 258 8e-69
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 119 3e-27
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 116 4e-26
gi|38201714 ELAV-like 1 [Homo sapiens] 115 5e-26
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 114 1e-25
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 114 1e-25
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 109 4e-24
gi|55956788 nucleolin [Homo sapiens] 108 6e-24
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ... 103 3e-22
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ... 103 3e-22
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ... 103 3e-22
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ... 103 3e-22
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 99 8e-21
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 96 7e-20
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 96 7e-20
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 94 3e-19
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 93 4e-19
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 93 4e-19
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 93 4e-19
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 93 4e-19
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 93 4e-19
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 728 bits (1878), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MNVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQ 60
MNVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQ
Sbjct: 1 MNVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQ 60
Query: 61 LADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSA 120
LADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSA
Sbjct: 61 LADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSA 120
Query: 121 FGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREA 180
FGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREA
Sbjct: 121 FGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREA 180
Query: 181 ELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSH 240
ELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSH
Sbjct: 181 ELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSH 240
Query: 241 EAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNL 300
EAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNL
Sbjct: 241 EAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNL 300
Query: 301 DDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSK 360
DDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSK
Sbjct: 301 DDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSK 360
Query: 361 PLSIALAQRH 370
PLSIALAQRH
Sbjct: 361 PLSIALAQRH 370
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 560 bits (1444), Expect = e-160
Identities = 279/370 (75%), Positives = 323/370 (87%), Gaps = 1/370 (0%)
Query: 1 MNVAAK-YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFL 59
MN AA Y MASLYVGDLH+DVTE +L+ KFS GPVLSIR+CRD +TRRSLGYAYVNF
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 60 QLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFS 119
Q ADA++ALDTMNFD+IKGK IR+MWSQRD LR+SG+GNVFIKNLDKSIDNK LY+ FS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 120 AFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDRE 179
AFG ILS KV+ D+ GSKGYAFVHF+ Q AAD+AIE+MNG LL KVFVGRFK+RK+RE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 180 AELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDS 239
AEL +KA EFTNVYIKNFG ++DDE LK++FS++GKTLSVKVM D +GKSKGFGFVS++
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 240 HEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKN 299
HE A KAVEEMNG++I+G++IFVGRAQKKVERQAELK+ FEQLK+ERI QGV LYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 300 LDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGS 359
LDDTIDDEKLR EFS FGSI+ KVM E+G+SKGFG +CFSSPE+ATKA+TEMNGRI+GS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 360 KPLSIALAQR 369
KPL +ALAQR
Sbjct: 361 KPLYVALAQR 370
Score = 184 bits (468), Expect = 8e-47
Identities = 111/293 (37%), Positives = 169/293 (57%), Gaps = 20/293 (6%)
Query: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
K + ++++ +L + L+ FS G +LS ++ D+ S GYA+V+F A
Sbjct: 95 KSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAAD 152
Query: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
KA++ MN ++ + + + +R+A L + NV+IKN + +D+++L E FS
Sbjct: 153 KAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFS 212
Query: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
FGK LS KVM D G SKG+ FV ++ A++A+EEMNGK + G +FVGR + + +R
Sbjct: 213 QFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
Query: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
+AEL+ K + N+YIKN +DDE+L+ FS +G S KVM + G+
Sbjct: 273 QAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED-GR 331
Query: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ER+A L + Q
Sbjct: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQ 384
Score = 103 bits (257), Expect = 2e-22
Identities = 68/206 (33%), Positives = 114/206 (55%), Gaps = 26/206 (12%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
++Y+ + +V ++ L FS G LS+++ RD +S G+ +V++ + DA KA++
Sbjct: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
Query: 71 MNFDIIKGKSIRLMWSQ----RDAYLRRS-------------GIGNVFIKNLDKSIDNKT 113
MN I GK I + +Q R A L+R G+ N++IKNLD +ID++
Sbjct: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
Query: 114 LYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFK 173
L + FS FG I S+KVM +D SKG+ FV F + A +A+ EMNG+++ ++V +
Sbjct: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
Query: 174 NRKDREAELRSKASEFTNVYIKNFGG 199
+++R+A L TN Y++ G
Sbjct: 370 RKEERKAHL-------TNQYMQRVAG 388
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 560 bits (1444), Expect = e-160
Identities = 279/370 (75%), Positives = 323/370 (87%), Gaps = 1/370 (0%)
Query: 1 MNVAAK-YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFL 59
MN AA Y MASLYVGDLH+DVTE +L+ KFS GPVLSIR+CRD +TRRSLGYAYVNF
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 60 QLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFS 119
Q ADA++ALDTMNFD+IKGK IR+MWSQRD LR+SG+GNVFIKNLDKSIDNK LY+ FS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 120 AFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDRE 179
AFG ILS KV+ D+ GSKGYAFVHF+ Q AAD+AIE+MNG LL KVFVGRFK+RK+RE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 180 AELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDS 239
AEL +KA EFTNVYIKNFG ++DDE LK++FS++GKTLSVKVM D +GKSKGFGFVS++
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 240 HEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKN 299
HE A KAVEEMNG++I+G++IFVGRAQKKVERQAELK+ FEQLK+ERI QGV LYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 300 LDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGS 359
LDDTIDDEKLR EFS FGSI+ KVM E+G+SKGFG +CFSSPE+ATKA+TEMNGRI+GS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 360 KPLSIALAQR 369
KPL +ALAQR
Sbjct: 361 KPLYVALAQR 370
Score = 184 bits (468), Expect = 8e-47
Identities = 111/293 (37%), Positives = 169/293 (57%), Gaps = 20/293 (6%)
Query: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
K + ++++ +L + L+ FS G +LS ++ D+ S GYA+V+F A
Sbjct: 95 KSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAAD 152
Query: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
KA++ MN ++ + + + +R+A L + NV+IKN + +D+++L E FS
Sbjct: 153 KAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFS 212
Query: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
FGK LS KVM D G SKG+ FV ++ A++A+EEMNGK + G +FVGR + + +R
Sbjct: 213 QFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
Query: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
+AEL+ K + N+YIKN +DDE+L+ FS +G S KVM + G+
Sbjct: 273 QAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED-GR 331
Query: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ER+A L + Q
Sbjct: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQ 384
Score = 103 bits (257), Expect = 2e-22
Identities = 68/206 (33%), Positives = 114/206 (55%), Gaps = 26/206 (12%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
++Y+ + +V ++ L FS G LS+++ RD +S G+ +V++ + DA KA++
Sbjct: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
Query: 71 MNFDIIKGKSIRLMWSQ----RDAYLRRS-------------GIGNVFIKNLDKSIDNKT 113
MN I GK I + +Q R A L+R G+ N++IKNLD +ID++
Sbjct: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
Query: 114 LYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFK 173
L + FS FG I S+KVM +D SKG+ FV F + A +A+ EMNG+++ ++V +
Sbjct: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
Query: 174 NRKDREAELRSKASEFTNVYIKNFGG 199
+++R+A L TN Y++ G
Sbjct: 370 RKEERKAHL-------TNQYMQRVAG 388
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 560 bits (1444), Expect = e-160
Identities = 279/370 (75%), Positives = 323/370 (87%), Gaps = 1/370 (0%)
Query: 1 MNVAAK-YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFL 59
MN AA Y MASLYVGDLH+DVTE +L+ KFS GPVLSIR+CRD +TRRSLGYAYVNF
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 60 QLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFS 119
Q ADA++ALDTMNFD+IKGK IR+MWSQRD LR+SG+GNVFIKNLDKSIDNK LY+ FS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 120 AFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDRE 179
AFG ILS KV+ D+ GSKGYAFVHF+ Q AAD+AIE+MNG LL KVFVGRFK+RK+RE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 180 AELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDS 239
AEL +KA EFTNVYIKNFG ++DDE LK++FS++GKTLSVKVM D +GKSKGFGFVS++
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 240 HEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKN 299
HE A KAVEEMNG++I+G++IFVGRAQKKVERQAELK+ FEQLK+ERI QGV LYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 300 LDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGS 359
LDDTIDDEKLR EFS FGSI+ KVM E+G+SKGFG +CFSSPE+ATKA+TEMNGRI+GS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 360 KPLSIALAQR 369
KPL +ALAQR
Sbjct: 361 KPLYVALAQR 370
Score = 184 bits (468), Expect = 8e-47
Identities = 111/293 (37%), Positives = 169/293 (57%), Gaps = 20/293 (6%)
Query: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
K + ++++ +L + L+ FS G +LS ++ D+ S GYA+V+F A
Sbjct: 95 KSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAAD 152
Query: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
KA++ MN ++ + + + +R+A L + NV+IKN + +D+++L E FS
Sbjct: 153 KAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFS 212
Query: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
FGK LS KVM D G SKG+ FV ++ A++A+EEMNGK + G +FVGR + + +R
Sbjct: 213 QFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
Query: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
+AEL+ K + N+YIKN +DDE+L+ FS +G S KVM + G+
Sbjct: 273 QAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED-GR 331
Query: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ER+A L + Q
Sbjct: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQ 384
Score = 103 bits (257), Expect = 2e-22
Identities = 68/206 (33%), Positives = 114/206 (55%), Gaps = 26/206 (12%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
++Y+ + +V ++ L FS G LS+++ RD +S G+ +V++ + DA KA++
Sbjct: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
Query: 71 MNFDIIKGKSIRLMWSQ----RDAYLRRS-------------GIGNVFIKNLDKSIDNKT 113
MN I GK I + +Q R A L+R G+ N++IKNLD +ID++
Sbjct: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
Query: 114 LYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFK 173
L + FS FG I S+KVM +D SKG+ FV F + A +A+ EMNG+++ ++V +
Sbjct: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
Query: 174 NRKDREAELRSKASEFTNVYIKNFGG 199
+++R+A L TN Y++ G
Sbjct: 370 RKEERKAHL-------TNQYMQRVAG 388
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 546 bits (1406), Expect = e-155
Identities = 265/366 (72%), Positives = 313/366 (85%)
Query: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
A Y MASLYVGDLH DVTE +L+ KFS GP+LSIR+CRD +TRRSLGYAYVNF Q AD
Sbjct: 5 APSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPAD 64
Query: 64 AQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGK 123
A++ALDTMNFD+IKGK +R+MWSQRD LR+SG+GN+FIKNLDKSIDNK LY+ FSAFG
Sbjct: 65 AERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGN 124
Query: 124 ILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELR 183
ILS KV+ D+ GSKGY FVHF+ Q AA+RAIE+MNG LL KVFVGRFK+RK+REAEL
Sbjct: 125 ILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELG 184
Query: 184 SKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAA 243
++A EFTNVYIKNFG DMDDERLKD+F K+G LSVKVMTD SGKSKGFGFVSF+ HE A
Sbjct: 185 ARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDA 244
Query: 244 KKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDT 303
+KAV+EMNG+++NG+ I+VGRAQKKVERQ ELK+ FEQ+K++RI QGV LY+KNLDD
Sbjct: 245 QKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDG 304
Query: 304 IDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLS 363
IDDE+LR EFS FG+I+ KVM E G+SKGFG +CFSSPE+ATKA+TEMNGRI+ +KPL
Sbjct: 305 IDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLY 364
Query: 364 IALAQR 369
+ALAQR
Sbjct: 365 VALAQR 370
Score = 179 bits (454), Expect = 4e-45
Identities = 107/293 (36%), Positives = 167/293 (56%), Gaps = 20/293 (6%)
Query: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
K + ++++ +L + L+ FS G +LS ++ D+ S GY +V+F A+
Sbjct: 95 KSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAE 152
Query: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
+A++ MN ++ + + + +R+A L R NV+IKN + +D++ L + F
Sbjct: 153 RAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFG 212
Query: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
FG LS KVM+D+ G SKG+ FV F+ A +A++EMNGK L G +++VGR + + +R
Sbjct: 213 KFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER 272
Query: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
+ EL+ K + N+Y+KN +DDERL+ FS +G S KVM + G+
Sbjct: 273 QTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG-GR 331
Query: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ERQA L + Q
Sbjct: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQ 384
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 511 bits (1315), Expect = e-145
Identities = 249/363 (68%), Positives = 299/363 (82%)
Query: 7 YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQK 66
Y ASLYVGDLH DVTE +L+ KFS GP+LSIRICRD +T S YAYVNF DA+
Sbjct: 8 YPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEH 67
Query: 67 ALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILS 126
ALDTMNFD+IKGK +R+MWSQRD LR+SG+GN+F+KNLDKSI+NK LY+ SAFG ILS
Sbjct: 68 ALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILS 127
Query: 127 SKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKA 186
V+ D+ GSKGY FVHF+ AA+RAI++MNG LL G KVFVG+FK+RK+REAEL ++A
Sbjct: 128 CNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARA 187
Query: 187 SEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKA 246
EF NVYIKNFG DMDDERLKD+F K+G LSVKVMTD SGKSKGFGFVSF+ HE A+KA
Sbjct: 188 KEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKA 247
Query: 247 VEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDD 306
V+EMNG+++NG+ I+VGRAQKKVERQ ELK+ FEQ+K++RI Q V LY+KNLDD IDD
Sbjct: 248 VDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDD 307
Query: 307 EKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIAL 366
E+LR FS FG+I+ KVM E G+SKGFG +CFSSPE+ATKA+TEMNGRI+ +KPL +AL
Sbjct: 308 ERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVAL 367
Query: 367 AQR 369
AQR
Sbjct: 368 AQR 370
Score = 174 bits (442), Expect = 9e-44
Identities = 107/293 (36%), Positives = 164/293 (55%), Gaps = 20/293 (6%)
Query: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
K + +++V +L + L+ S G +LS + D+ S GY +V+F A+
Sbjct: 95 KSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAE 152
Query: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
+A+ MN ++ G+ + + +R+A L R NV+IKN + +D++ L + F
Sbjct: 153 RAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFG 212
Query: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
FG LS KVM+D+ G SKG+ FV F+ A +A++EMNGK L G +++VGR + + +R
Sbjct: 213 KFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER 272
Query: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
+ EL+ + N+Y+KN +DDERL+ FS +G S KVM + G+
Sbjct: 273 QTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG-GR 331
Query: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ERQA L + Q
Sbjct: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQ 384
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 489 bits (1260), Expect = e-138
Identities = 233/363 (64%), Positives = 299/363 (82%)
Query: 7 YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQK 66
Y +ASLYVGDLH DVTE +L+ KFS GP+LSIR+CRD TRRSLGYAY+NF Q ADA++
Sbjct: 8 YPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAER 67
Query: 67 ALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILS 126
ALDTMNF+++KG+ IR+MWSQRD LR+SG+GN+FIKNL+ SIDNK LY+ FS FG ILS
Sbjct: 68 ALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILS 127
Query: 127 SKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKA 186
KV D+ GS+G+ FVHF+ AA +AI MNG LL KVFVG FK+R++REAEL ++A
Sbjct: 128 CKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARA 187
Query: 187 SEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKA 246
EFTN+Y+KN D+D++ L+D+FS++GK LSVKVM D+SG S+ FGFV+F+ HE A+KA
Sbjct: 188 LEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKA 247
Query: 247 VEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDD 306
V MNG++++G+L++ GRAQK+VERQ ELK+ FEQ+K++R+R QGV LY+KNLDD+IDD
Sbjct: 248 VVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDD 307
Query: 307 EKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIAL 366
+KLR EFS +G I+ KVM E G SKGFG +CFSSPE+ATKA+TEMNGRI+G+KPL +AL
Sbjct: 308 DKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVAL 367
Query: 367 AQR 369
AQR
Sbjct: 368 AQR 370
Score = 171 bits (432), Expect = 1e-42
Identities = 104/293 (35%), Positives = 166/293 (56%), Gaps = 20/293 (6%)
Query: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
K + ++++ +L + L+ FST G +LS ++ D+ S G+ +V+F AQ
Sbjct: 95 KSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQ 152
Query: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
+A++TMN ++ + + + +R+A L R N+++KNL +D + L + FS
Sbjct: 153 QAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFS 212
Query: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
FGK+LS KVM D+ G S+ + FV+F+ A +A+ MNGK + G ++ GR + R +R
Sbjct: 213 QFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVER 272
Query: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
+ EL+ + + N+Y+KN +DD++L+ FS YG S KVMT+ G
Sbjct: 273 QNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEG-GH 331
Query: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ER+A L + Q
Sbjct: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQ 384
Score = 96.7 bits (239), Expect = 3e-20
Identities = 63/199 (31%), Positives = 107/199 (53%), Gaps = 19/199 (9%)
Query: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
A ++YV +L DV E L FS G +LS+++ RD + S + +VNF + +
Sbjct: 185 ARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEE 243
Query: 64 AQKALDTMNFDIIKGKSI-----------------RLMWSQRDAYLRRSGIGNVFIKNLD 106
AQKA+ MN + G+ + R ++D R G+ N+++KNLD
Sbjct: 244 AQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGV-NLYVKNLD 302
Query: 107 KSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCK 166
SID+ L + FS +G I S+KVM++ SKG+ FV F + A +A+ EMNG+++
Sbjct: 303 DSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKP 362
Query: 167 VFVGRFKNRKDREAELRSK 185
++V + +++R+A L ++
Sbjct: 363 LYVALAQRKEERKAILTNQ 381
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 451 bits (1159), Expect = e-127
Identities = 225/364 (61%), Positives = 289/364 (79%), Gaps = 1/364 (0%)
Query: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
KY A+LYVGDL DVTED+L++KF GP+ RICRD VTR LGY YVNF ADA+
Sbjct: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
Query: 66 KALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKIL 125
AL+TMNFD+I GK RLMWSQ D LR+SG+GN+FIKNLDKSIDN+ L+ FSAFG IL
Sbjct: 74 WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNIL 133
Query: 126 SSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSK 185
S KV+ DD GSKGYA+VHF + +AA+RAI MNG L +V+VGRFK ++R AE+R++
Sbjct: 134 SCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTR 193
Query: 186 -ASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244
+ FTNV++KN G D+DDE+LK++F +YG T SVKV+ D+SGKSKGFGFV +++HEAA+
Sbjct: 194 DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQ 253
Query: 245 KAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTI 304
KAV +++G+ I+G++++VGRAQKK+ER AEL++ FE+L+ + GV +YIKNLD+TI
Sbjct: 254 KAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETI 313
Query: 305 DDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364
+DEKL+ EFSSFGSISR KVM E GQ KGFG++CFSS E+ATKA+ EMNGRI+GSKPL +
Sbjct: 314 NDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373
Query: 365 ALAQ 368
L Q
Sbjct: 374 TLGQ 377
Score = 144 bits (364), Expect = 1e-34
Identities = 97/283 (34%), Positives = 154/283 (54%), Gaps = 23/283 (8%)
Query: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
K + ++++ +L + LF FS G +LS ++ D S GYAYV+F LA A
Sbjct: 102 KSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAAN 159
Query: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYLR---RSGIGNVFIKNLDKSIDNKTLYEHF 118
+A+ MN + + + + +R A +R R+ NVF+KN+ ID++ L E F
Sbjct: 160 RAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELF 219
Query: 119 SAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKD 177
+G S KV+ D G SKG+ FV ++ AA +A+ +++GK + G ++VGR + + +
Sbjct: 220 CEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIE 279
Query: 178 REAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSG 227
R AELR + +YIKN ++DE+LK+ FS +G KVM + G
Sbjct: 280 RLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEV-G 338
Query: 228 KSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFV--GRAQKK 268
+ KGFG V F S E A KAV+EMNGR + + + V G+A+++
Sbjct: 339 QGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARRR 381
Score = 138 bits (348), Expect = 7e-33
Identities = 89/273 (32%), Positives = 150/273 (54%), Gaps = 19/273 (6%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEEM 157
+++ +LD + LY+ F G + +++ D + GY +V+F+ + A+ A+ M
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTL 217
N L+ G K F + DR + S N++IKN +D+ L +FS +G L
Sbjct: 80 NFDLING-KPFRLMWSQPDDR-----LRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNIL 133
Query: 218 SVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQ 277
S KV+ D +G SKG+ +V FDS AA +A+ MNG +N + ++VGR + ER AE++
Sbjct: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
Query: 278 MFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE-EGQSKGFGL 336
R+R +++KN+ D IDDEKL+ F +G VKV+++ G+SKGFG
Sbjct: 193 ------RDR---ATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
Query: 337 ICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
+ + + E A KA+ +++G+ + K L + AQ+
Sbjct: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQK 276
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 258 bits (658), Expect = 8e-69
Identities = 124/196 (63%), Positives = 156/196 (79%)
Query: 9 MASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68
MASLYVGDLH +VTE +L+ KFS GP+LSIRICRD++TRRSLGYAYVN+ Q DA++AL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 69 DTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSK 128
+T+NFD+IKG+ +R+MWSQRD LR+SG+GNVFIKNL K+IDNK LY FSAFG ILS K
Sbjct: 61 ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 129 VMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASE 188
V D++G KGY FVHFQ Q +A+RAI+ MNG L K+FVGRFK+ K+REAE + A +
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180
Query: 189 FTNVYIKNFGGDMDDE 204
T+ +K+F D D+E
Sbjct: 181 STSADVKDFEEDTDEE 196
Score = 111 bits (277), Expect = 1e-24
Identities = 68/180 (37%), Positives = 104/180 (57%), Gaps = 9/180 (5%)
Query: 97 IGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAI 154
+ ++++ +L + LYE FS G ILS ++ D + S GYA+V++Q A RA+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 155 EEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
E +N ++KG V + R+ LR S NV+IKN G +D++ L ++FS +G
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSLRK--SGVGNVFIKNLGKTIDNKALYNIFSAFG 114
Query: 215 KTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAE 274
LS KV D G KG+GFV F E+A++A++ MNG +N + IFVGR + ER+AE
Sbjct: 115 NILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173
Score = 75.5 bits (184), Expect = 7e-14
Identities = 52/182 (28%), Positives = 93/182 (51%), Gaps = 19/182 (10%)
Query: 191 NVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEE 249
++Y+ + ++ + L + FS G LS+++ D + +S G+ +V++ AK+A+E
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 250 MNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGV-KLYIKNLDDTIDDEK 308
+N I G+ + + +Q R L++ GV ++IKNL TID++
Sbjct: 63 LNFDVIKGRPVRIMWSQ----RDPSLRK-------------SGVGNVFIKNLGKTIDNKA 105
Query: 309 LRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
L N FS+FG+I KV +E KG+G + F E A +A+ MNG L + + + +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165
Query: 369 RH 370
H
Sbjct: 166 SH 167
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 258 bits (658), Expect = 8e-69
Identities = 124/196 (63%), Positives = 156/196 (79%)
Query: 9 MASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68
MASLYVGDLH +VTE +L+ KFS GP+LSIRICRD++TRRSLGYAYVN+ Q DA++AL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 69 DTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSK 128
+T+NFD+IKG+ +R+MWSQRD LR+SG+GNVFIKNL K+IDNK LY FSAFG ILS K
Sbjct: 61 ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 129 VMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASE 188
V D++G KGY FVHFQ Q +A+RAI+ MNG L K+FVGRFK+ K+REAE + A +
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180
Query: 189 FTNVYIKNFGGDMDDE 204
T+ +K+F D D+E
Sbjct: 181 STSADVKDFEEDTDEE 196
Score = 111 bits (277), Expect = 1e-24
Identities = 68/180 (37%), Positives = 104/180 (57%), Gaps = 9/180 (5%)
Query: 97 IGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAI 154
+ ++++ +L + LYE FS G ILS ++ D + S GYA+V++Q A RA+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 155 EEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
E +N ++KG V + R+ LR S NV+IKN G +D++ L ++FS +G
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSLRK--SGVGNVFIKNLGKTIDNKALYNIFSAFG 114
Query: 215 KTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAE 274
LS KV D G KG+GFV F E+A++A++ MNG +N + IFVGR + ER+AE
Sbjct: 115 NILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173
Score = 75.5 bits (184), Expect = 7e-14
Identities = 52/182 (28%), Positives = 93/182 (51%), Gaps = 19/182 (10%)
Query: 191 NVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEE 249
++Y+ + ++ + L + FS G LS+++ D + +S G+ +V++ AK+A+E
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 250 MNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGV-KLYIKNLDDTIDDEK 308
+N I G+ + + +Q R L++ GV ++IKNL TID++
Sbjct: 63 LNFDVIKGRPVRIMWSQ----RDPSLRK-------------SGVGNVFIKNLGKTIDNKA 105
Query: 309 LRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
L N FS+FG+I KV +E KG+G + F E A +A+ MNG L + + + +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165
Query: 369 RH 370
H
Sbjct: 166 SH 167
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 119 bits (299), Expect = 3e-27
Identities = 77/190 (40%), Positives = 114/190 (60%), Gaps = 7/190 (3%)
Query: 3 VAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLA 62
++ + + A++YVG L V+E LL+ F GPV++ + +D+VT + GY +V FL
Sbjct: 6 ISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEE 65
Query: 63 DAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIG-NVFIKNLDKSIDNKTLYEHFSAF 121
DA A+ MN + GK IR+ ++ A+ + +G N+FI NLD ID K LY+ FSAF
Sbjct: 66 DADYAIKIMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAF 123
Query: 122 GKILSS-KVMSD-DQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
G IL + K+M D D G SKGYAF++F + A+D AIE MNG+ L + V + +KD
Sbjct: 124 GVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDS 182
Query: 179 EAELRSKASE 188
+ E A+E
Sbjct: 183 KGERHGSAAE 192
Score = 77.8 bits (190), Expect = 1e-14
Identities = 56/180 (31%), Positives = 93/180 (51%), Gaps = 13/180 (7%)
Query: 94 RSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSK--GYAFVHFQNQSAAD 151
R+ V++ LD+ + L+E F G ++++ + D + GY FV F ++ AD
Sbjct: 9 RNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDAD 68
Query: 152 RAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEF-TNVYIKNFGGDMDDERLKDVF 210
AI+ MN L G + V + A +K + N++I N ++D++ L D F
Sbjct: 69 YAIKIMNMIKLYGKPIRVNK--------ASAHNKNLDVGANIFIGNLDPEIDEKLLYDTF 120
Query: 211 SKYGKTLSV-KVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKK 268
S +G L K+M D +G SKG+ F++F S +A+ A+E MNG+ + + I V A KK
Sbjct: 121 SAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK 180
Score = 71.2 bits (173), Expect = 1e-12
Identities = 54/188 (28%), Positives = 98/188 (52%), Gaps = 21/188 (11%)
Query: 184 SKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEA 242
S+ ++ VY+ + + L ++F + G ++ + D +G+ +G+GFV F S E
Sbjct: 7 SERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEED 66
Query: 243 AKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDD 302
A A++ MN + G+ I V +A A K + G ++I NLD
Sbjct: 67 ADYAIKIMNMIKLYGKPIRVNKAS------AHNKNLDV-----------GANIFIGNLDP 109
Query: 303 TIDDEKLRNEFSSFGSISRV-KVMQEE--GQSKGFGLICFSSPEDATKAMTEMNGRILGS 359
ID++ L + FS+FG I + K+M++ G SKG+ I F+S + + A+ MNG+ L +
Sbjct: 110 EIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCN 169
Query: 360 KPLSIALA 367
+P++++ A
Sbjct: 170 RPITVSYA 177
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 291 QGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKA 348
Q +Y+ LD+ + + L F G + + ++ GQ +G+G + F S EDA A
Sbjct: 11 QDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYA 70
Query: 349 MTEMNGRILGSKPLSIALAQRH 370
+ MN L KP+ + A H
Sbjct: 71 IKIMNMIKLYGKPIRVNKASAH 92
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 116 bits (290), Expect = 4e-26
Identities = 78/268 (29%), Positives = 131/268 (48%), Gaps = 25/268 (9%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+LYVG+L DVTE L+ + FS +GP S ++ + + Y +V F + DA AL
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAA 67
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRR--SGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSK 128
MN I GK +++ W+ + ++ S +VF+ +L I + + F+ FGKI ++
Sbjct: 68 MNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDAR 127
Query: 129 VMSD--DQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVG------------RFKN 174
V+ D SKGY FV F N+ A+ AI M G+ L G ++ + N
Sbjct: 128 VVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENN 187
Query: 175 RKDREAE--LRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGF 232
K E + + + VY + D+ ++ FS +G+ + ++V + KG+
Sbjct: 188 TKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE-----KGY 242
Query: 233 GFVSFDSHEAAKKAVEEMNGRDINGQLI 260
FV F +HE+A A+ +NG I G ++
Sbjct: 243 SFVRFSTHESAAHAIVSVNGTTIEGHVV 270
Score = 102 bits (254), Expect = 5e-22
Identities = 70/260 (26%), Positives = 127/260 (48%), Gaps = 13/260 (5%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159
+++ NL + + + + FS G S K++++ + Y FV F A A+ MNG
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
Query: 160 KLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSV 219
+ + G +V V N + + S +V++ + ++ E +K F+ +GK
Sbjct: 71 RKILGKEVKV----NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
Query: 220 KVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVER-QAELKQ 277
+V+ D ++GKSKG+GFVSF + A+ A+ M G+ + G+ I A +K ++ +
Sbjct: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
Query: 278 MFEQLKRERIRGCQGVK---LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGF 334
+QL+ E + K +Y + + D+ +R FS FG I ++V E KG+
Sbjct: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
Query: 335 GLICFSSPEDATKAMTEMNG 354
+ FS+ E A A+ +NG
Sbjct: 243 SFVRFSTHESAAHAIVSVNG 262
Score = 72.0 bits (175), Expect = 8e-13
Identities = 48/180 (26%), Positives = 86/180 (47%), Gaps = 17/180 (9%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMN 251
+Y+ N D+ + + +FS+ G S K++T+ + + FV F H A A+ MN
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
Query: 252 GRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRN 311
GR I G+ + V A ++ + F +++ +L I E +++
Sbjct: 70 GRKILGKEVKVNWATTPSSQKKDTSNHFH--------------VFVGDLSPEITTEDIKS 115
Query: 312 EFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
F+ FG IS +V+++ G+SKG+G + F + DA A+ M G+ LG + + A R
Sbjct: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/77 (24%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
++Y G + + +T+ L+ + FS G ++ IR+ ++ GY++V F A A+ +
Sbjct: 206 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVS 259
Query: 71 MNFDIIKGKSIRLMWSQ 87
+N I+G ++ W +
Sbjct: 260 VNGTTIEGHVVKCYWGK 276
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 115 bits (289), Expect = 5e-26
Identities = 81/299 (27%), Positives = 147/299 (49%), Gaps = 49/299 (16%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+L V L ++T+D L FS++G V S ++ RD+V SLGY +VN++ DA++A++T
Sbjct: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
+N ++ K+I++ +++ + + + N++I L +++ K + + FS FG+I++S+V+
Sbjct: 81 LNGLRLQSKTIKVSYARPSSEVIKD--ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
Query: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGKLLKG------------------------ 164
D S+G AF+ F +S A+ AI NG G
Sbjct: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198
Query: 165 -----CKVFVGRFKNRKDR---------------EAELRSKASEFTNVYIKNFGGDMDDE 204
+ F G ++ R + AS ++I N G D D+
Sbjct: 199 LYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEG 258
Query: 205 RLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFV 262
L +F +G +VKV+ D ++ K KGFGFV+ ++E A A+ +NG + +++ V
Sbjct: 259 ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317
Score = 99.4 bits (246), Expect = 5e-21
Identities = 78/309 (25%), Positives = 140/309 (45%), Gaps = 47/309 (15%)
Query: 96 GIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG--SKGYAFVHFQNQSAADRA 153
G N+ + L +++ L FS+ G++ S+K++ D S GY FV++ A+RA
Sbjct: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
Query: 154 IEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKY 213
I +NG L+ K K A S+ + N+YI M + ++D+FS++
Sbjct: 78 INTLNGLRLQS--------KTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
Query: 214 GKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQ----LIFVGRAQKK 268
G+ ++ +V+ D ++G S+G F+ FD A++A+ NG G + +
Sbjct: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
Query: 269 VERQAELKQMFEQLKR--------------------ERIRGCQGVK----------LYIK 298
+ A L Q++ R + + G GV ++I
Sbjct: 190 NKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIY 249
Query: 299 NLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRI 356
NL D+ L F FG+++ VKV+++ + KGFG + ++ E+A A+ +NG
Sbjct: 250 NLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYR 309
Query: 357 LGSKPLSIA 365
LG K L ++
Sbjct: 310 LGDKILQVS 318
Score = 70.1 bits (170), Expect = 3e-12
Identities = 52/183 (28%), Positives = 87/183 (47%), Gaps = 23/183 (12%)
Query: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
TN+ + +M + L+ +FS G+ S K++ D +G S G+GFV++ + + A++A+
Sbjct: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79
Query: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
+NG + + I V A+ E + LYI L T+ +
Sbjct: 80 TLNGLRLQSKTIKVSYARPSSE------------------VIKDANLYISGLPRTMTQKD 121
Query: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRIL--GSKPLSI 364
+ + FS FG I SRV V Q G S+G I F +A +A+T NG S+P+++
Sbjct: 122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 181
Query: 365 ALA 367
A
Sbjct: 182 KFA 184
Score = 53.9 bits (128), Expect = 2e-07
Identities = 56/222 (25%), Positives = 90/222 (40%), Gaps = 53/222 (23%)
Query: 10 ASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALD 69
A+LY+ L +T+ + FS G +++ R+ DQ T S G A++ F + ++A++A+
Sbjct: 106 ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAIT 165
Query: 70 TMNFDIIKG----------------KSIRLMWSQRDAYLRR------------------- 94
+ N G K++ L+ + RR
Sbjct: 166 SFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGV 225
Query: 95 ------SGI---GN------VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSK 137
SG+ GN +FI NL + D L++ F FG + + KV+ D K
Sbjct: 226 DHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCK 285
Query: 138 GYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDRE 179
G+ FV N A AI +NG L G K+ FK K +
Sbjct: 286 GFGFVTMTNYEEAAMAIASLNGYRL-GDKILQVSFKTNKSHK 326
Score = 47.0 bits (110), Expect = 3e-05
Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Query: 279 FEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFG 335
+E E RG G L + L + ++LR+ FSS G + K+++++ G S G+G
Sbjct: 5 YEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYG 64
Query: 336 LICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
+ + + +DA +A+ +NG L SK + ++ A+
Sbjct: 65 FVNYVTAKDAERAINTLNGLRLQSKTIKVSYAR 97
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 114 bits (285), Expect = 1e-25
Identities = 80/283 (28%), Positives = 133/283 (46%), Gaps = 38/283 (13%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLG---------------YAY 55
+LYVG+L DVTE L+ + FS +GP S ++ +Q R + Y +
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCF 69
Query: 56 VNFLQLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRR--SGIGNVFIKNLDKSIDNKT 113
V F + DA AL MN I GK +++ W+ + ++ S +VF+ +L I +
Sbjct: 70 VEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTED 129
Query: 114 LYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVG- 170
+ F+ FGKI ++V+ D SKGY FV F N+ A+ AI M G+ L G ++
Sbjct: 130 IKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 189
Query: 171 -----------RFKNRKDREAE--LRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTL 217
+ N K E + + + VY + D+ ++ FS +G+ +
Sbjct: 190 ATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIM 249
Query: 218 SVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLI 260
++V + KG+ FV F +HE+A A+ +NG I G ++
Sbjct: 250 EIRVFPE-----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 287
Score = 94.0 bits (232), Expect = 2e-19
Identities = 71/277 (25%), Positives = 128/277 (46%), Gaps = 30/277 (10%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKG-----------------YAFV 142
+++ NL + + + + FS G S K++++ S+ Y FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 143 HFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMD 202
F A A+ MNG+ + G +V V N + + S +V++ + ++
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKV----NWATTPSSQKKDTSNHFHVFVGDLSPEIT 126
Query: 203 DERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIF 261
E +K F+ +GK +V+ D ++GKSKG+GFVSF + A+ A+ M G+ + G+ I
Sbjct: 127 TEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR 186
Query: 262 VGRAQKKVER-QAELKQMFEQLKRERIRGCQGVK---LYIKNLDDTIDDEKLRNEFSSFG 317
A +K ++ + +QL+ E + K +Y + + D+ +R FS FG
Sbjct: 187 TNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFG 246
Query: 318 SISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNG 354
I ++V E KG+ + FS+ E A A+ +NG
Sbjct: 247 QIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNG 279
Score = 67.4 bits (163), Expect = 2e-11
Identities = 51/196 (26%), Positives = 87/196 (44%), Gaps = 32/196 (16%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSS-----GKSKGFG-----------FV 235
+Y+ N D+ + + +FS+ G S K++T+ S GF FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 236 SFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKL 295
F H A A+ MNGR I G+ + V A ++ + F +
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFH--------------V 116
Query: 296 YIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMN 353
++ +L I E +++ F+ FG IS +V+++ G+SKG+G + F + DA A+ M
Sbjct: 117 FVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMG 176
Query: 354 GRILGSKPLSIALAQR 369
G+ LG + + A R
Sbjct: 177 GQWLGGRQIRTNWATR 192
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/77 (24%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
++Y G + + +T+ L+ + FS G ++ IR+ ++ GY++V F A A+ +
Sbjct: 223 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVS 276
Query: 71 MNFDIIKGKSIRLMWSQ 87
+N I+G ++ W +
Sbjct: 277 VNGTTIEGHVVKCYWGK 293
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 114 bits (285), Expect = 1e-25
Identities = 80/269 (29%), Positives = 134/269 (49%), Gaps = 27/269 (10%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+LYVG+L DVTE L+ + FS +GP + ++ D T + Y +V F + A AL
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRR--SGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSK 128
MN I GK +++ W+ + ++ S +VF+ +L I + + F+ FG+I ++
Sbjct: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDAR 125
Query: 129 VMSD--DQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKV---------------FVGR 171
V+ D SKGY FV F N+ A+ AI++M G+ L G ++ +
Sbjct: 126 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESN 185
Query: 172 FKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKG 231
K E +S S T VY + ++ ++ FS +G+ + ++V D KG
Sbjct: 186 TKQLSYDEVVNQSSPSNCT-VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
Query: 232 FGFVSFDSHEAAKKAVEEMNGRDINGQLI 260
+ FV F+SHE+A A+ +NG I G ++
Sbjct: 240 YSFVRFNSHESAAHAIVSVNGTTIEGHVV 268
Score = 101 bits (252), Expect = 9e-22
Identities = 66/260 (25%), Positives = 127/260 (48%), Gaps = 13/260 (5%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159
+++ NL + + + + FS G + K++ D G+ Y FV F A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 160 KLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSV 219
+ + G +V V N + + S +V++ + ++ E +K F+ +G+
Sbjct: 69 RKIMGKEVKV----NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
Query: 220 KVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVER-QAELKQ 277
+V+ D ++GKSKG+GFVSF + A+ A+++M G+ + G+ I A +K ++ +
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
Query: 278 MFEQLKRERI---RGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGF 334
+QL + + +Y + + ++ +R FS FG I ++V + KG+
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
Query: 335 GLICFSSPEDATKAMTEMNG 354
+ F+S E A A+ +NG
Sbjct: 241 SFVRFNSHESAAHAIVSVNG 260
Score = 73.6 bits (179), Expect = 3e-13
Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 17/180 (9%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMN 251
+Y+ N D+ + + +FS+ G + K++ D++G + FV F H A A+ MN
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 252 GRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRN 311
GR I G+ + V A ++ + F +++ +L I E ++
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHFH--------------VFVGDLSPEITTEDIKA 113
Query: 312 EFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
F+ FG IS +V+++ G+SKG+G + F + DA A+ +M G+ LG + + A R
Sbjct: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
++Y G + + +TE L+ + FS G ++ IR+ D+ GY++V F A A+ +
Sbjct: 204 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVS 257
Query: 71 MNFDIIKGKSIRLMWSQ 87
+N I+G ++ W +
Sbjct: 258 VNGTTIEGHVVKCYWGK 274
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 109 bits (272), Expect = 4e-24
Identities = 79/280 (28%), Positives = 133/280 (47%), Gaps = 38/280 (13%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+LYVG+L DVTE L+ + FS +GP + ++ D T + Y +V F + A AL
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGN-------------VFIKNLDKSIDNKTLYEH 117
MN I GK +++ W+ + ++ + VF+ +L I + +
Sbjct: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
Query: 118 FSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKV-------- 167
F+ FG+I ++V+ D SKGY FV F N+ A+ AI++M G+ L G ++
Sbjct: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
Query: 168 -------FVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVK 220
+ K E +S S T VY + ++ ++ FS +G+ + ++
Sbjct: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCT-VYCGGVTSGLTEQLMRQTFSPFGQIMEIR 244
Query: 221 VMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLI 260
V D KG+ FV F+SHE+A A+ +NG I G ++
Sbjct: 245 VFPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
Score = 100 bits (248), Expect = 3e-21
Identities = 65/267 (24%), Positives = 130/267 (48%), Gaps = 16/267 (5%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159
+++ NL + + + + FS G + K++ D G+ Y FV F A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 160 KLLKGCKVFVGRFKNRKDREAELRS-------KASEFTNVYIKNFGGDMDDERLKDVFSK 212
+ + G +V V ++ + S ++ + +V++ + ++ E +K F+
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
Query: 213 YGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVER 271
+G+ +V+ D ++GKSKG+GFVSF + A+ A+++M G+ + G+ I A +K
Sbjct: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
Query: 272 -QAELKQMFEQLKRERI---RGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE 327
++ + +QL + + +Y + + ++ +R FS FG I ++V +
Sbjct: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
Query: 328 EGQSKGFGLICFSSPEDATKAMTEMNG 354
KG+ + F+S E A A+ +NG
Sbjct: 249 ----KGYSFVRFNSHESAAHAIVSVNG 271
Score = 72.8 bits (177), Expect = 5e-13
Identities = 49/180 (27%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMN 251
+Y+ N D+ + + +FS+ G + K++ D++G + FV F H A A+ MN
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 252 GRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRN 311
GR I G+ + V A ++ K R +++ +L I E ++
Sbjct: 68 GRKIMGKEVKVNWATTP---SSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKA 124
Query: 312 EFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
F+ FG IS +V+++ G+SKG+G + F + DA A+ +M G+ LG + + A R
Sbjct: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
++Y G + + +TE L+ + FS G ++ IR+ D+ GY++V F A A+ +
Sbjct: 215 TVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVS 268
Query: 71 MNFDIIKGKSIRLMWSQ 87
+N I+G ++ W +
Sbjct: 269 VNGTTIEGHVVKCYWGK 285
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 108 bits (271), Expect = 6e-24
Identities = 99/358 (27%), Positives = 168/358 (46%), Gaps = 34/358 (9%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPV--LSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68
+L+VG+L+ + + L S V L++ R +TR+ + YV+F D +KAL
Sbjct: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364
Query: 69 DTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSK 128
+ + G I+L + + + KNL + L E F +I +
Sbjct: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420
Query: 129 VMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKV---FVG-RFKNRKDREAELRS 184
++S D SKG A++ F+ ++ A++ EE G + G + + G + +N+ R + +
Sbjct: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
Query: 185 KASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244
+ E + + N +E L++VF K +KV + +GKSKG+ F+ F S E AK
Sbjct: 481 WSGESKTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
Query: 245 KAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTI 304
+A+ N R+I G+ I ++E Q R L++K L +
Sbjct: 538 EALNSCNKREIEGRAI-------RLELQGPRGS-------PNARSQPSKTLFVKGLSEDT 583
Query: 305 DDEKLRNEFSSFGSI-SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEM-NGRILGSK 360
+E L+ F GS+ +R+ +E G SKGFG + F+S EDA A M +G I G+K
Sbjct: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639
Score = 83.6 bits (205), Expect = 3e-16
Identities = 74/236 (31%), Positives = 113/236 (47%), Gaps = 26/236 (11%)
Query: 49 RSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWS----QRDAYLRRSGIGNVF--- 101
+S G AY+ F ADA+K + I G+SI L ++ Q Y R G + +
Sbjct: 427 KSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDY--RGGKNSTWSGE 484
Query: 102 -----IKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIE 155
+ NL S +TL E F K KV + G SKGYAF+ F + A A+
Sbjct: 485 SKTLVLSNLSYSATEETLQE---VFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALN 541
Query: 156 EMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGK 215
N + ++G + + R A RS+ S+ +++K D +E LK+ F
Sbjct: 542 SCNKREIEGRAIRLELQGPRGSPNA--RSQPSK--TLFVKGLSEDTTEETLKESFDG--- 594
Query: 216 TLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270
++ +++TD +G SKGFGFV F+S E AK A E M +I+G + + A+ K E
Sbjct: 595 SVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
Score = 68.6 bits (166), Expect = 9e-12
Identities = 60/232 (25%), Positives = 106/232 (45%), Gaps = 21/232 (9%)
Query: 136 SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIK 195
++ + +V F++ ++A+E L G KVF K K + + + K + + K
Sbjct: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKDSK-KERDARTLLAK 398
Query: 196 NFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDI 255
N + + LK+VF + V GKSKG ++ F + A+K EE G +I
Sbjct: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
Query: 256 NGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSS 315
+G+ I + +K + Q + K G + L + NL + +E L+ F
Sbjct: 455 DGRSISLYYTGEKGQNQD-----YRGGKNSTWSG-ESKTLVLSNLSYSATEETLQEVFEK 508
Query: 316 FGSISRVKVMQEE-GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIAL 366
+ +KV Q + G+SKG+ I F+S EDA +A+ N R + + + + L
Sbjct: 509 ---ATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 191 NVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEM 250
N+++ N + LK S + V+ G ++ FG+V F+S E +KA+E +
Sbjct: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALE-L 366
Query: 251 NGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLR 310
G + G I + + + K K+ER L KNL + ++L+
Sbjct: 367 TGLKVFGNEIKLEKPKGK------------DSKKER----DARTLLAKNLPYKVTQDELK 410
Query: 311 NEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364
F + ++++ ++G+SKG I F + DA K E G + + +S+
Sbjct: 411 EVFED---AAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISL 461
Score = 38.1 bits (87), Expect = 0.013
Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+L+V L D TE+ L F G V + RI D+ T S G+ +V+F DA+ A +
Sbjct: 573 TLFVKGLSEDTTEETLKESFD--GSVRA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEA 629
Query: 71 MNFDIIKGKSIRLMWSQ 87
M I G + L W++
Sbjct: 630 MEDGEIDGNKVTLDWAK 646
>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 6 [Homo sapiens]
Length = 562
Score = 103 bits (256), Expect = 3e-22
Identities = 77/284 (27%), Positives = 141/284 (49%), Gaps = 33/284 (11%)
Query: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
++VG + D+ ED L F GP+ +R+ D +T + GYA+V F AQ+A+
Sbjct: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
Query: 72 N-FDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
N +I GK I + S + +F+ ++ KS + + E FS + L+ ++
Sbjct: 224 NNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
Query: 131 ----SDDQGSKGYAFVHFQNQSAADRAIEE-MNGKLLKGCKVFVGRFKNR-KDREAELRS 184
D + ++G+ F+ +++ A +A M+GK+ V + + +D + E+ +
Sbjct: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
Query: 185 KASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244
K ++++N + +E L+ FS++GK VK K K + F+ FD + A
Sbjct: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVK-------KLKDYAFIHFDERDGAV 385
Query: 245 KAVEEMNGRDINGQLIFV--------GRAQKKVERQAELKQMFE 280
KA+EEMNG+D+ G+ I + R ++K +RQA QM++
Sbjct: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYD 429
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/284 (25%), Positives = 121/284 (42%), Gaps = 55/284 (19%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG--SKGYAFVHFQNQSAADRAIEEM 157
+F+ + + + L F G I ++M D ++GYAFV F + AA A++
Sbjct: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
Query: 158 N------GKLLKGC------KVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDER 205
N GK + C ++FVG K +E L EF+ V E
Sbjct: 224 NNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILE----EFSKV----------TEG 269
Query: 206 LKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265
L DV + D K++GF F+ ++ H+ A +A + ++G++
Sbjct: 270 LTDVILYH--------QPDDKKKNRGFCFLEYEDHKTAAQARRRL----MSGKV------ 311
Query: 266 QKKVERQAELKQMFEQLKRERIRGCQGVK-LYIKNLDDTIDDEKLRNEFSSFGSISRVKV 324
KV + + ++ VK L+++NL +T+ +E L FS FG + RVK
Sbjct: 312 --KVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKK 369
Query: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
+ K + I F + A KAM EMNG+ L + + I A+
Sbjct: 370 L------KDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 2 [Homo sapiens]
Length = 464
Score = 103 bits (256), Expect = 3e-22
Identities = 77/284 (27%), Positives = 141/284 (49%), Gaps = 33/284 (11%)
Query: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
++VG + D+ ED L F GP+ +R+ D +T + GYA+V F AQ+A+
Sbjct: 66 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 125
Query: 72 N-FDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
N +I GK I + S + +F+ ++ KS + + E FS + L+ ++
Sbjct: 126 NNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 177
Query: 131 ----SDDQGSKGYAFVHFQNQSAADRAIEE-MNGKLLKGCKVFVGRFKNR-KDREAELRS 184
D + ++G+ F+ +++ A +A M+GK+ V + + +D + E+ +
Sbjct: 178 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 237
Query: 185 KASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244
K ++++N + +E L+ FS++GK VK K K + F+ FD + A
Sbjct: 238 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVK-------KLKDYAFIHFDERDGAV 287
Query: 245 KAVEEMNGRDINGQLIFV--------GRAQKKVERQAELKQMFE 280
KA+EEMNG+D+ G+ I + R ++K +RQA QM++
Sbjct: 288 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYD 331
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/284 (25%), Positives = 121/284 (42%), Gaps = 55/284 (19%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG--SKGYAFVHFQNQSAADRAIEEM 157
+F+ + + + L F G I ++M D ++GYAFV F + AA A++
Sbjct: 66 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 125
Query: 158 N------GKLLKGC------KVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDER 205
N GK + C ++FVG K +E L EF+ V E
Sbjct: 126 NNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILE----EFSKV----------TEG 171
Query: 206 LKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265
L DV + D K++GF F+ ++ H+ A +A + ++G++
Sbjct: 172 LTDVILYH--------QPDDKKKNRGFCFLEYEDHKTAAQARRRL----MSGKV------ 213
Query: 266 QKKVERQAELKQMFEQLKRERIRGCQGVK-LYIKNLDDTIDDEKLRNEFSSFGSISRVKV 324
KV + + ++ VK L+++NL +T+ +E L FS FG + RVK
Sbjct: 214 --KVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKK 271
Query: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
+ K + I F + A KAM EMNG+ L + + I A+
Sbjct: 272 L------KDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 309
>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 5 [Homo sapiens]
Length = 561
Score = 103 bits (256), Expect = 3e-22
Identities = 77/284 (27%), Positives = 141/284 (49%), Gaps = 33/284 (11%)
Query: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
++VG + D+ ED L F GP+ +R+ D +T + GYA+V F AQ+A+
Sbjct: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
Query: 72 N-FDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
N +I GK I + S + +F+ ++ KS + + E FS + L+ ++
Sbjct: 224 NNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
Query: 131 ----SDDQGSKGYAFVHFQNQSAADRAIEE-MNGKLLKGCKVFVGRFKNR-KDREAELRS 184
D + ++G+ F+ +++ A +A M+GK+ V + + +D + E+ +
Sbjct: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
Query: 185 KASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244
K ++++N + +E L+ FS++GK VK K K + F+ FD + A
Sbjct: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVK-------KLKDYAFIHFDERDGAV 385
Query: 245 KAVEEMNGRDINGQLIFV--------GRAQKKVERQAELKQMFE 280
KA+EEMNG+D+ G+ I + R ++K +RQA QM++
Sbjct: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYD 429
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/284 (25%), Positives = 121/284 (42%), Gaps = 55/284 (19%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG--SKGYAFVHFQNQSAADRAIEEM 157
+F+ + + + L F G I ++M D ++GYAFV F + AA A++
Sbjct: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
Query: 158 N------GKLLKGC------KVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDER 205
N GK + C ++FVG K +E L EF+ V E
Sbjct: 224 NNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILE----EFSKV----------TEG 269
Query: 206 LKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265
L DV + D K++GF F+ ++ H+ A +A + ++G++
Sbjct: 270 LTDVILYH--------QPDDKKKNRGFCFLEYEDHKTAAQARRRL----MSGKV------ 311
Query: 266 QKKVERQAELKQMFEQLKRERIRGCQGVK-LYIKNLDDTIDDEKLRNEFSSFGSISRVKV 324
KV + + ++ VK L+++NL +T+ +E L FS FG + RVK
Sbjct: 312 --KVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKK 369
Query: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
+ K + I F + A KAM EMNG+ L + + I A+
Sbjct: 370 L------KDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 1 [Homo sapiens]
Length = 623
Score = 103 bits (256), Expect = 3e-22
Identities = 77/284 (27%), Positives = 141/284 (49%), Gaps = 33/284 (11%)
Query: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
++VG + D+ ED L F GP+ +R+ D +T + GYA+V F AQ+A+
Sbjct: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
Query: 72 N-FDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
N +I GK I + S + +F+ ++ KS + + E FS + L+ ++
Sbjct: 224 NNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
Query: 131 ----SDDQGSKGYAFVHFQNQSAADRAIEE-MNGKLLKGCKVFVGRFKNR-KDREAELRS 184
D + ++G+ F+ +++ A +A M+GK+ V + + +D + E+ +
Sbjct: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
Query: 185 KASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244
K ++++N + +E L+ FS++GK VK K K + F+ FD + A
Sbjct: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVK-------KLKDYAFIHFDERDGAV 385
Query: 245 KAVEEMNGRDINGQLIFV--------GRAQKKVERQAELKQMFE 280
KA+EEMNG+D+ G+ I + R ++K +RQA QM++
Sbjct: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYD 429
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/284 (25%), Positives = 121/284 (42%), Gaps = 55/284 (19%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG--SKGYAFVHFQNQSAADRAIEEM 157
+F+ + + + L F G I ++M D ++GYAFV F + AA A++
Sbjct: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
Query: 158 N------GKLLKGC------KVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDER 205
N GK + C ++FVG K +E L EF+ V E
Sbjct: 224 NNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILE----EFSKV----------TEG 269
Query: 206 LKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265
L DV + D K++GF F+ ++ H+ A +A + ++G++
Sbjct: 270 LTDVILYH--------QPDDKKKNRGFCFLEYEDHKTAAQARRRL----MSGKV------ 311
Query: 266 QKKVERQAELKQMFEQLKRERIRGCQGVK-LYIKNLDDTIDDEKLRNEFSSFGSISRVKV 324
KV + + ++ VK L+++NL +T+ +E L FS FG + RVK
Sbjct: 312 --KVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKK 369
Query: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
+ K + I F + A KAM EMNG+ L + + I A+
Sbjct: 370 L------KDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 98.6 bits (244), Expect = 8e-21
Identities = 76/322 (23%), Positives = 145/322 (45%), Gaps = 63/322 (19%)
Query: 2 NVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQL 61
N A +L V L ++T+D F ++G + S ++ RD++T +SLGY +VN+
Sbjct: 31 NGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDP 90
Query: 62 ADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAF 121
DA KA++T+N ++ K+I++ +++ + R N+++ L K++ K + + FS +
Sbjct: 91 NDADKAINTLNGLKLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMSQKEMEQLFSQY 148
Query: 122 GKILSSKVMSDDQG--SKGYAFVHFQNQSAADRAIEEMNG-KLLKGCKVFVGRFKN---- 174
G+I++S+++ D S+G F+ F + A+ AI+ +NG K L + +F N
Sbjct: 149 GRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQ 208
Query: 175 -----------------------------RKDREAELRSKASEFTNVYIKNFGG------ 199
R D + F+ + I G
Sbjct: 209 KTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGL 268
Query: 200 ------------------DMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSH 240
+ D+ L +F +G +VKV+ D ++ K KGFGFV+ ++
Sbjct: 269 SGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNY 328
Query: 241 EAAKKAVEEMNGRDINGQLIFV 262
+ A A+ +NG + +++ V
Sbjct: 329 DEAAMAIASLNGYRLGERVLQV 350
Score = 92.8 bits (229), Expect = 4e-19
Identities = 79/322 (24%), Positives = 141/322 (43%), Gaps = 65/322 (20%)
Query: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156
N+ + L +++ F + G I S K++ D S GY FV++ + + AD+AI
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
+NG L K KV R + R+A N+Y+ M + ++ +FS+YG
Sbjct: 100 LNGLKLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMSQKEMEQLFSQYG 149
Query: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGR------------------DI 255
+ ++ +++ D +G S+G GF+ FD A++A++ +NG+
Sbjct: 150 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQK 209
Query: 256 NGQLIFVGRAQKKVERQA-------------ELKQMFEQLKR------ERIRGCQGVKL- 295
GQ + Q R A L M +KR + + G GV L
Sbjct: 210 TGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLS 269
Query: 296 ----------YIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPE 343
++ NL D+ L F FG+++ VKV+++ + KGFG + ++ +
Sbjct: 270 GGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYD 329
Query: 344 DATKAMTEMNGRILGSKPLSIA 365
+A A+ +NG LG + L ++
Sbjct: 330 EAAMAIASLNGYRLGERVLQVS 351
Score = 67.0 bits (162), Expect = 3e-11
Identities = 50/179 (27%), Positives = 80/179 (44%), Gaps = 25/179 (13%)
Query: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
TN+ + +M + K +F G S K++ D +G+S G+GFV++ A KA+
Sbjct: 39 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 98
Query: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
+NG + + I V A R + LY+ L T+ ++
Sbjct: 99 TLNGLKLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMSQKE 140
Query: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIA 365
+ FS +G I SR+ V Q G S+G G I F +A +A+ +NG+ KPL A
Sbjct: 141 MEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ----KPLGAA 195
Score = 47.8 bits (112), Expect = 2e-05
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352
L + L + ++ ++ F S G I K+++++ GQS G+G + +S P DA KA+ +
Sbjct: 41 LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTL 100
Query: 353 NGRILGSKPLSIALAQ 368
NG L +K + ++ A+
Sbjct: 101 NGLKLQTKTIKVSYAR 116
Score = 43.5 bits (101), Expect = 3e-04
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
+F+ NL D L++ F FG + + KV+ D KG+ FV N A AI +
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 158 NGKLLKGCKVFVGRFKNRKDREA 180
NG L G +V FK K +A
Sbjct: 339 NGYRL-GERVLQVSFKTSKQHKA 360
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 95.5 bits (236), Expect = 7e-20
Identities = 66/213 (30%), Positives = 113/213 (53%), Gaps = 11/213 (5%)
Query: 60 QLADAQKALDTMNF-DIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHF 118
QL + Q A TM F D + ++ M +QR L + + V++ ++ + T+ + F
Sbjct: 51 QLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQAF 106
Query: 119 SAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRK 176
+ FG I S + D KG+AFV ++ AA A+E+MN +L G + VGR N
Sbjct: 107 APFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIG 166
Query: 177 DREA---ELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGF 232
+ +L +A F +Y+ + D+ D+ +K VF +GK S + D ++GK KG+
Sbjct: 167 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 226
Query: 233 GFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265
GF+ ++ ++++ AV MN D+ GQ + VG+A
Sbjct: 227 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 259
Score = 75.5 bits (184), Expect = 7e-14
Identities = 46/179 (25%), Positives = 94/179 (52%), Gaps = 10/179 (5%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEM 250
VY+ + ++ ++ ++ F+ +G S+ + DS + K KGF FV ++ EAA+ A+E+M
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 251 NGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLR 310
N + G+ I VGR + Q + Q+ E+ + ++Y+ ++ + D+ ++
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 200
Query: 311 NEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALA 367
+ F +FG I + ++ G+ KG+G I + + + A++ MN LG + L + A
Sbjct: 201 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 259
Score = 68.2 bits (165), Expect = 1e-11
Identities = 44/174 (25%), Positives = 84/174 (48%), Gaps = 11/174 (6%)
Query: 9 MASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68
M +YVG ++ ++ ED + + F+ GP+ SI + D VT + G+A+V + AQ AL
Sbjct: 85 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 144
Query: 69 DTMNFDIIKGKSIRLMWSQRDAYLR---------RSGIGNVFIKNLDKSIDNKTLYEHFS 119
+ MN ++ G++I++ + +++ ++ + + + + F
Sbjct: 145 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 204
Query: 120 AFGKILSSKVMSDDQGS--KGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGR 171
AFGKI S + D KGY F+ ++ ++ A+ MN L G + VG+
Sbjct: 205 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 258
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 95.5 bits (236), Expect = 7e-20
Identities = 66/213 (30%), Positives = 113/213 (53%), Gaps = 11/213 (5%)
Query: 60 QLADAQKALDTMNF-DIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHF 118
QL + Q A TM F D + ++ M +QR L + + V++ ++ + T+ + F
Sbjct: 94 QLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQAF 149
Query: 119 SAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRK 176
+ FG I S + D KG+AFV ++ AA A+E+MN +L G + VGR N
Sbjct: 150 APFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIG 209
Query: 177 DREA---ELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGF 232
+ +L +A F +Y+ + D+ D+ +K VF +GK S + D ++GK KG+
Sbjct: 210 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 269
Query: 233 GFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265
GF+ ++ ++++ AV MN D+ GQ + VG+A
Sbjct: 270 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
Score = 75.5 bits (184), Expect = 7e-14
Identities = 46/179 (25%), Positives = 94/179 (52%), Gaps = 10/179 (5%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEM 250
VY+ + ++ ++ ++ F+ +G S+ + DS + K KGF FV ++ EAA+ A+E+M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 251 NGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLR 310
N + G+ I VGR + Q + Q+ E+ + ++Y+ ++ + D+ ++
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 243
Query: 311 NEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALA 367
+ F +FG I + ++ G+ KG+G I + + + A++ MN LG + L + A
Sbjct: 244 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
Score = 68.2 bits (165), Expect = 1e-11
Identities = 44/174 (25%), Positives = 84/174 (48%), Gaps = 11/174 (6%)
Query: 9 MASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68
M +YVG ++ ++ ED + + F+ GP+ SI + D VT + G+A+V + AQ AL
Sbjct: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
Query: 69 DTMNFDIIKGKSIRLMWSQRDAYLR---------RSGIGNVFIKNLDKSIDNKTLYEHFS 119
+ MN ++ G++I++ + +++ ++ + + + + F
Sbjct: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
Query: 120 AFGKILSSKVMSDDQGS--KGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGR 171
AFGKI S + D KGY F+ ++ ++ A+ MN L G + VG+
Sbjct: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 93.6 bits (231), Expect = 3e-19
Identities = 54/172 (31%), Positives = 94/172 (54%), Gaps = 6/172 (3%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEEM 157
V++ ++ + T+ + F+ FG I S + D KG+AFV ++ AA A+E+M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 158 NGKLLKGCKVFVGRFKNRKDREA---ELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
N +L G + VGR N + +L +A F +Y+ + D+ D+ +K VF +G
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
Query: 215 KTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265
K S + D ++GK KG+GF+ ++ ++++ AV MN D+ GQ + VG+A
Sbjct: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
Score = 75.5 bits (184), Expect = 7e-14
Identities = 46/179 (25%), Positives = 94/179 (52%), Gaps = 10/179 (5%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEM 250
VY+ + ++ ++ ++ F+ +G S+ + DS + K KGF FV ++ EAA+ A+E+M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 251 NGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLR 310
N + G+ I VGR + Q + Q+ E+ + ++Y+ ++ + D+ ++
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 226
Query: 311 NEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALA 367
+ F +FG I + ++ G+ KG+G I + + + A++ MN LG + L + A
Sbjct: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
Score = 68.2 bits (165), Expect = 1e-11
Identities = 44/174 (25%), Positives = 84/174 (48%), Gaps = 11/174 (6%)
Query: 9 MASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68
M +YVG ++ ++ ED + + F+ GP+ SI + D VT + G+A+V + AQ AL
Sbjct: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
Query: 69 DTMNFDIIKGKSIRLMWSQRDAYLR---------RSGIGNVFIKNLDKSIDNKTLYEHFS 119
+ MN ++ G++I++ + +++ ++ + + + + F
Sbjct: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
Query: 120 AFGKILSSKVMSDDQGS--KGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGR 171
AFGKI S + D KGY F+ ++ ++ A+ MN L G + VG+
Sbjct: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 92.8 bits (229), Expect = 4e-19
Identities = 79/322 (24%), Positives = 147/322 (45%), Gaps = 66/322 (20%)
Query: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156
N+ + L +++ + F + G+I S K++ D S GY FV++ + A++AI
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
+NG L K KV R + R+A N+Y+ M + L+ +FS+YG
Sbjct: 110 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 159
Query: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDING-----QLIFVGRAQKK 268
+ ++ +++ D +G S+G GF+ FD A++A++ +NG+ +G + F +K
Sbjct: 160 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 219
Query: 269 VERQAELKQMFE------------QLKRERIRG----CQGVK------------------ 294
QA L Q+++ Q +R R+ GVK
Sbjct: 220 -SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNI 278
Query: 295 ---------LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPE 343
+++ NL D+ L F FG+++ VKV+++ + KGFG + ++ +
Sbjct: 279 PGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 338
Query: 344 DATKAMTEMNGRILGSKPLSIA 365
+A A+ +NG LG + L ++
Sbjct: 339 EAAMAIASLNGYRLGDRVLQVS 360
Score = 87.8 bits (216), Expect = 1e-17
Identities = 46/156 (29%), Positives = 95/156 (60%), Gaps = 4/156 (2%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+L V L ++T++ F ++G + S ++ RD++T +SLGY +VN++ DA+KA++T
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
+N ++ K+I++ +++ + R N+++ L K++ K L + FS +G+I++S+++
Sbjct: 110 LNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 167
Query: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGKLLKG 164
D S+G F+ F + A+ AI+ +NG+ G
Sbjct: 168 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 203
Score = 66.2 bits (160), Expect = 4e-11
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
TN+ + +M E + +F G+ S K++ D +G+S G+GFV++ + A+KA+
Sbjct: 49 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 108
Query: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
+NG + + I V A R + LY+ L T+ ++
Sbjct: 109 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 150
Query: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355
L FS +G I SR+ V Q G S+G G I F +A +A+ +NG+
Sbjct: 151 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 199
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352
L + L + E+ R+ F S G I K+++++ GQS G+G + + P+DA KA+ +
Sbjct: 51 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 110
Query: 353 NGRILGSKPLSIALAQ 368
NG L +K + ++ A+
Sbjct: 111 NGLRLQTKTIKVSYAR 126
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEM 250
+++ N D D+ L +F +G +VKV+ D ++ K KGFGFV+ +++ A A+ +
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 251 NGRDINGQLIFVGRAQKKVER 271
NG + +++ V K +
Sbjct: 348 NGYRLGDRVLQVSFKTNKAHK 368
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
+A R A+LYV L +T+ L + FS G +++ RI DQVT S G ++ F + +
Sbjct: 129 SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIE 188
Query: 64 AQKALDTMN 72
A++A+ +N
Sbjct: 189 AEEAIKGLN 197
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
+F+ NL D L++ F FG + + KV+ D KG+ FV N A AI +
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 158 NGKLLKGCKVFVGRFKNRK 176
NG L G +V FK K
Sbjct: 348 NGYRL-GDRVLQVSFKTNK 365
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 92.8 bits (229), Expect = 4e-19
Identities = 79/322 (24%), Positives = 147/322 (45%), Gaps = 66/322 (20%)
Query: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156
N+ + L +++ + F + G+I S K++ D S GY FV++ + A++AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
+NG L K KV R + R+A N+Y+ M + L+ +FS+YG
Sbjct: 107 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 156
Query: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDING-----QLIFVGRAQKK 268
+ ++ +++ D +G S+G GF+ FD A++A++ +NG+ +G + F +K
Sbjct: 157 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 216
Query: 269 VERQAELKQMFE------------QLKRERIRG----CQGVK------------------ 294
QA L Q+++ Q +R R+ GVK
Sbjct: 217 -SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNI 275
Query: 295 ---------LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPE 343
+++ NL D+ L F FG+++ VKV+++ + KGFG + ++ +
Sbjct: 276 PGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 335
Query: 344 DATKAMTEMNGRILGSKPLSIA 365
+A A+ +NG LG + L ++
Sbjct: 336 EAAMAIASLNGYRLGDRVLQVS 357
Score = 87.8 bits (216), Expect = 1e-17
Identities = 46/156 (29%), Positives = 95/156 (60%), Gaps = 4/156 (2%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+L V L ++T++ F ++G + S ++ RD++T +SLGY +VN++ DA+KA++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
+N ++ K+I++ +++ + R N+++ L K++ K L + FS +G+I++S+++
Sbjct: 107 LNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGKLLKG 164
D S+G F+ F + A+ AI+ +NG+ G
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200
Score = 66.2 bits (160), Expect = 4e-11
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
TN+ + +M E + +F G+ S K++ D +G+S G+GFV++ + A+KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
+NG + + I V A R + LY+ L T+ ++
Sbjct: 106 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 147
Query: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355
L FS +G I SR+ V Q G S+G G I F +A +A+ +NG+
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 196
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352
L + L + E+ R+ F S G I K+++++ GQS G+G + + P+DA KA+ +
Sbjct: 48 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107
Query: 353 NGRILGSKPLSIALAQ 368
NG L +K + ++ A+
Sbjct: 108 NGLRLQTKTIKVSYAR 123
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEM 250
+++ N D D+ L +F +G +VKV+ D ++ K KGFGFV+ +++ A A+ +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 251 NGRDINGQLIFVGRAQKKVER 271
NG + +++ V K +
Sbjct: 345 NGYRLGDRVLQVSFKTNKAHK 365
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
+A R A+LYV L +T+ L + FS G +++ RI DQVT S G ++ F + +
Sbjct: 126 SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIE 185
Query: 64 AQKALDTMN 72
A++A+ +N
Sbjct: 186 AEEAIKGLN 194
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
+F+ NL D L++ F FG + + KV+ D KG+ FV N A AI +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 158 NGKLLKGCKVFVGRFKNRK 176
NG L G +V FK K
Sbjct: 345 NGYRL-GDRVLQVSFKTNK 362
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 92.8 bits (229), Expect = 4e-19
Identities = 79/322 (24%), Positives = 147/322 (45%), Gaps = 66/322 (20%)
Query: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156
N+ + L +++ + F + G+I S K++ D S GY FV++ + A++AI
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
+NG L K KV R + R+A N+Y+ M + L+ +FS+YG
Sbjct: 124 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 173
Query: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDING-----QLIFVGRAQKK 268
+ ++ +++ D +G S+G GF+ FD A++A++ +NG+ +G + F +K
Sbjct: 174 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 233
Query: 269 VERQAELKQMFE------------QLKRERIRG----CQGVK------------------ 294
QA L Q+++ Q +R R+ GVK
Sbjct: 234 -SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNI 292
Query: 295 ---------LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPE 343
+++ NL D+ L F FG+++ VKV+++ + KGFG + ++ +
Sbjct: 293 PGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 352
Query: 344 DATKAMTEMNGRILGSKPLSIA 365
+A A+ +NG LG + L ++
Sbjct: 353 EAAMAIASLNGYRLGDRVLQVS 374
Score = 87.8 bits (216), Expect = 1e-17
Identities = 46/156 (29%), Positives = 95/156 (60%), Gaps = 4/156 (2%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+L V L ++T++ F ++G + S ++ RD++T +SLGY +VN++ DA+KA++T
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
+N ++ K+I++ +++ + R N+++ L K++ K L + FS +G+I++S+++
Sbjct: 124 LNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
Query: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGKLLKG 164
D S+G F+ F + A+ AI+ +NG+ G
Sbjct: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 217
Score = 66.2 bits (160), Expect = 4e-11
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
TN+ + +M E + +F G+ S K++ D +G+S G+GFV++ + A+KA+
Sbjct: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
Query: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
+NG + + I V A R + LY+ L T+ ++
Sbjct: 123 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 164
Query: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355
L FS +G I SR+ V Q G S+G G I F +A +A+ +NG+
Sbjct: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 213
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352
L + L + E+ R+ F S G I K+++++ GQS G+G + + P+DA KA+ +
Sbjct: 65 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 124
Query: 353 NGRILGSKPLSIALAQ 368
NG L +K + ++ A+
Sbjct: 125 NGLRLQTKTIKVSYAR 140
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEM 250
+++ N D D+ L +F +G +VKV+ D ++ K KGFGFV+ +++ A A+ +
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 251 NGRDINGQLIFVGRAQKKVER 271
NG + +++ V K +
Sbjct: 362 NGYRLGDRVLQVSFKTNKAHK 382
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
+A R A+LYV L +T+ L + FS G +++ RI DQVT S G ++ F + +
Sbjct: 143 SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIE 202
Query: 64 AQKALDTMN 72
A++A+ +N
Sbjct: 203 AEEAIKGLN 211
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
+F+ NL D L++ F FG + + KV+ D KG+ FV N A AI +
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 158 NGKLLKGCKVFVGRFKNRK 176
NG L G +V FK K
Sbjct: 362 NGYRL-GDRVLQVSFKTNK 379
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 92.8 bits (229), Expect = 4e-19
Identities = 79/322 (24%), Positives = 147/322 (45%), Gaps = 66/322 (20%)
Query: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156
N+ + L +++ + F + G+I S K++ D S GY FV++ + A++AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
+NG L K KV R + R+A N+Y+ M + L+ +FS+YG
Sbjct: 107 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 156
Query: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDING-----QLIFVGRAQKK 268
+ ++ +++ D +G S+G GF+ FD A++A++ +NG+ +G + F +K
Sbjct: 157 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 216
Query: 269 VERQAELKQMFE------------QLKRERIRG----CQGVK------------------ 294
QA L Q+++ Q +R R+ GVK
Sbjct: 217 -SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNI 275
Query: 295 ---------LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPE 343
+++ NL D+ L F FG+++ VKV+++ + KGFG + ++ +
Sbjct: 276 PGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 335
Query: 344 DATKAMTEMNGRILGSKPLSIA 365
+A A+ +NG LG + L ++
Sbjct: 336 EAAMAIASLNGYRLGDRVLQVS 357
Score = 87.8 bits (216), Expect = 1e-17
Identities = 46/156 (29%), Positives = 95/156 (60%), Gaps = 4/156 (2%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+L V L ++T++ F ++G + S ++ RD++T +SLGY +VN++ DA+KA++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
+N ++ K+I++ +++ + R N+++ L K++ K L + FS +G+I++S+++
Sbjct: 107 LNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGKLLKG 164
D S+G F+ F + A+ AI+ +NG+ G
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200
Score = 66.2 bits (160), Expect = 4e-11
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
TN+ + +M E + +F G+ S K++ D +G+S G+GFV++ + A+KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
+NG + + I V A R + LY+ L T+ ++
Sbjct: 106 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 147
Query: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355
L FS +G I SR+ V Q G S+G G I F +A +A+ +NG+
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 196
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352
L + L + E+ R+ F S G I K+++++ GQS G+G + + P+DA KA+ +
Sbjct: 48 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107
Query: 353 NGRILGSKPLSIALAQ 368
NG L +K + ++ A+
Sbjct: 108 NGLRLQTKTIKVSYAR 123
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEM 250
+++ N D D+ L +F +G +VKV+ D ++ K KGFGFV+ +++ A A+ +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 251 NGRDINGQLIFVGRAQKKVER 271
NG + +++ V K +
Sbjct: 345 NGYRLGDRVLQVSFKTNKAHK 365
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
+A R A+LYV L +T+ L + FS G +++ RI DQVT S G ++ F + +
Sbjct: 126 SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIE 185
Query: 64 AQKALDTMN 72
A++A+ +N
Sbjct: 186 AEEAIKGLN 194
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
+F+ NL D L++ F FG + + KV+ D KG+ FV N A AI +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 158 NGKLLKGCKVFVGRFKNRK 176
NG L G +V FK K
Sbjct: 345 NGYRL-GDRVLQVSFKTNK 362
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 92.8 bits (229), Expect = 4e-19
Identities = 80/322 (24%), Positives = 147/322 (45%), Gaps = 66/322 (20%)
Query: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156
N+ + L +++ + L F + G+I S K++ D S GY FV++ + A++AI
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
+NG L K KV R + R+A N+Y+ M + L+ +FS+YG
Sbjct: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149
Query: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDING-----QLIFVGRAQKK 268
+ ++ +++ D +G S+G GF+ FD A++A++ +NG+ G + F +K
Sbjct: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209
Query: 269 VERQAELKQMF------------EQLKRERIRG----CQGVK------------------ 294
QA L Q++ +Q +R R+ GVK
Sbjct: 210 T-NQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINI 268
Query: 295 ---------LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPE 343
+++ NL D+ L F FG+++ VKV+++ + KGFG + ++ +
Sbjct: 269 PGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYD 328
Query: 344 DATKAMTEMNGRILGSKPLSIA 365
+A A+ +NG LG + L ++
Sbjct: 329 EAAMAIASLNGYRLGDRVLQVS 350
Score = 89.0 bits (219), Expect = 6e-18
Identities = 46/152 (30%), Positives = 95/152 (62%), Gaps = 4/152 (2%)
Query: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
+L V L ++T++ L F ++G + S ++ RD++T +SLGY +VN++ DA+KA++T
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
+N ++ K+I++ +++ + R N+++ L K++ K L + FS +G+I++S+++
Sbjct: 100 LNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
Query: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGK 160
D S+G F+ F + A+ AI+ +NG+
Sbjct: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQ 189
Score = 68.6 bits (166), Expect = 9e-12
Identities = 49/169 (28%), Positives = 80/169 (47%), Gaps = 21/169 (12%)
Query: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
TN+ + +M E LK +F G+ S K++ D +G+S G+GFV++ + A+KA+
Sbjct: 39 TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
Query: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
+NG + + I V A R + LY+ L T+ ++
Sbjct: 99 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 140
Query: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355
L FS +G I SR+ V Q G S+G G I F +A +A+ +NG+
Sbjct: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQ 189
Score = 48.5 bits (114), Expect = 9e-06
Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
Query: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352
L + L + E+L++ F S G I K+++++ GQS G+G + + P+DA KA+ +
Sbjct: 41 LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
Query: 353 NGRILGSKPLSIALAQ 368
NG L +K + ++ A+
Sbjct: 101 NGLRLQTKTIKVSYAR 116
Score = 47.8 bits (112), Expect = 2e-05
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEM 250
+++ N D D+ L +F +G +VKV+ D ++ K KGFGFV+ +++ A A+ +
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 251 NGRDINGQLIFVGRAQKKVER 271
NG + +++ V K +
Sbjct: 338 NGYRLGDRVLQVSFKTNKTHK 358
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
+F+ NL D L++ F FG + + KV+ D KG+ FV N A AI +
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 158 NGKLLKGCKVFVGRFKNRKDREA 180
NG L G +V FK K +A
Sbjct: 338 NGYRL-GDRVLQVSFKTNKTHKA 359
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
+A R A+LYV L +T+ L + FS G +++ RI DQVT S G ++ F + +
Sbjct: 119 SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIE 178
Query: 64 AQKALDTMN 72
A++A+ +N
Sbjct: 179 AEEAIKGLN 187
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,588,216
Number of Sequences: 37866
Number of extensions: 459133
Number of successful extensions: 3301
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 252
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 1414
Number of HSP's gapped (non-prelim): 1112
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.