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Search of human proteins with 167857788
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
(383 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 787 0.0
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 635 0.0
gi|17986001 major histocompatibility complex, class I, B precurs... 145 6e-35
gi|24797067 major histocompatibility complex, class I, A precurs... 142 4e-34
gi|62912479 major histocompatibility complex, class I, E precurs... 141 9e-34
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 140 1e-33
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 140 2e-33
gi|52630342 major histocompatibility complex, class I, C precurs... 138 7e-33
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 137 1e-32
gi|149158702 major histocompatibility complex, class I, F isofor... 137 2e-32
gi|149158698 major histocompatibility complex, class I, F isofor... 137 2e-32
gi|4504417 major histocompatibility complex, class I-related [Ho... 134 1e-31
gi|4504415 major histocompatibility complex, class I, G precurso... 131 1e-30
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 127 2e-29
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 113 3e-25
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 104 1e-22
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 100 4e-21
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 88 1e-17
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 88 1e-17
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 83 4e-16
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 83 5e-16
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 75 1e-13
gi|149158700 major histocompatibility complex, class I, F isofor... 69 5e-12
gi|13375656 UL16 binding protein 3 [Homo sapiens] 60 3e-09
gi|110618227 CD1C antigen precursor [Homo sapiens] 58 1e-08
gi|21040249 retinoic acid early transcript 1E [Homo sapiens] 56 5e-08
gi|4502649 CD1D antigen precursor [Homo sapiens] 54 3e-07
gi|18426911 signal-regulatory protein alpha precursor [Homo sapi... 51 2e-06
gi|91105767 signal-regulatory protein alpha precursor [Homo sapi... 51 2e-06
gi|91105764 signal-regulatory protein alpha precursor [Homo sapi... 51 2e-06
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 787 bits (2032), Expect = 0.0
Identities = 383/383 (100%), Positives = 383/383 (100%)
Query: 1 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD 60
MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD
Sbjct: 1 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD 60
Query: 61 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCE 120
RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCE
Sbjct: 61 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCE 120
Query: 121 IHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY 180
IHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY
Sbjct: 121 IHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY 180
Query: 181 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR 240
RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR
Sbjct: 181 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR 240
Query: 241 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA 300
QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA
Sbjct: 241 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA 300
Query: 301 LVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHR 360
LVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHR
Sbjct: 301 LVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHR 360
Query: 361 DAAQLGFQPLMSATGSTGSTEGT 383
DAAQLGFQPLMSATGSTGSTEGT
Sbjct: 361 DAAQLGFQPLMSATGSTGSTEGT 383
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 635 bits (1637), Expect = 0.0
Identities = 316/382 (82%), Positives = 329/382 (86%)
Query: 1 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD 60
MGLG V L LA FPFAPP AAAEPHSLRYNL VLS DGSVQSGFL E HLDGQPFLR D
Sbjct: 1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD 60
Query: 61 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCE 120
RQK RAKPQGQWAE+VLG KTWD ET DLT NG+DLR TL HIKDQK GLHSLQEIRVCE
Sbjct: 61 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE 120
Query: 121 IHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY 180
IHED+STR S+HFYYDGELFLSQNLET+E T+PQSSRAQTLAMNV NF KEDAMKTKTHY
Sbjct: 121 IHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY 180
Query: 181 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR 240
AM ADCLQ+L+RYLKSGV +RRTVPPMVNVT SE SEGNITVTCRAS FYP NITL+WR
Sbjct: 181 HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR 240
Query: 241 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA 300
QDGVSLSH+TQQWGDVLPDGNGTYQTWVATRI QGEEQRFTCYMEHSGNH THPVPSGK
Sbjct: 241 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV 300
Query: 301 LVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHR 360
LVLQS F + A +III V CCKKKTSAAEGPELVSLQVLDQHPVGT DHR
Sbjct: 301 LVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR 360
Query: 361 DAAQLGFQPLMSATGSTGSTEG 382
DA QLGFQPLMS GSTGSTEG
Sbjct: 361 DATQLGFQPLMSDLGSTGSTEG 382
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 145 bits (366), Expect = 6e-35
Identities = 103/351 (29%), Positives = 174/351 (49%), Gaps = 34/351 (9%)
Query: 6 VLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR- 64
VLL L+ A A + HS+RY +S+ G + F++ G++D F+R+D
Sbjct: 9 VLLLLSAALALTETWAGS--HSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAAS 66
Query: 65 -RAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIK----DQKGGLHSLQEIRVC 119
R +P+ W E G + WD T+ Q R +L +++ + G H+LQ + C
Sbjct: 67 PREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGC 125
Query: 120 EIHEDSST-RGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKT 178
++ D RG + YDG+ +++ N + + T A T A W E A + +
Sbjct: 126 DVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTA-----ADTAAQITQRKW-EAAREAEQ 179
Query: 179 HYRAMQADCLQKLQRYLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITL 237
++ +C++ L+RYL++G + R PP +VT +S+ T+ C A FYP ITL
Sbjct: 180 RRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITL 239
Query: 238 TWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPS 297
TW++DG + +T + + P G+ T+Q W A + GEEQR+TC+++H G +P
Sbjct: 240 TWQRDGEDQTQDT-ELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEG------LP- 291
Query: 298 GKALVLQ---SQRTDFPYVS-----AAMPCFVIIIILCVPCCKKKTSAAEG 340
K L L+ S ++ P V A + VI ++ C++K+S +G
Sbjct: 292 -KPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKG 341
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 142 bits (359), Expect = 4e-34
Identities = 89/289 (30%), Positives = 149/289 (51%), Gaps = 16/289 (5%)
Query: 8 LFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQ--KRR 65
L L ++ A A HS+RY +S+ G + F+A G++D F+R+D +R
Sbjct: 9 LLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQR 68
Query: 66 AKPQGQWAENVLGAKTWDTETEDLTENGQ----DLRRTLTHIKDQKGGLHSLQEIRVCEI 121
+P+ W E G + WD ET ++ Q DL + + G H++Q + C++
Sbjct: 69 MEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYGCDV 127
Query: 122 HEDSS-TRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY 180
D RG R YDG+ +++ N + + T A +A +T E A + +
Sbjct: 128 GSDGRFLRGYRQDAYDGKDYIALNEDLRSWT------AADMAAQITKRKWEAAHEAEQLR 181
Query: 181 RAMQADCLQKLQRYLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTW 239
+ C++ L+RYL++G ++RT PP ++T +S+ T+ C A FYP ITLTW
Sbjct: 182 AYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTW 241
Query: 240 RQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
++DG + +T + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 242 QRDGEDQTQDT-ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 289
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 141 bits (356), Expect = 9e-34
Identities = 94/293 (32%), Positives = 148/293 (50%), Gaps = 18/293 (6%)
Query: 4 GRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQK 63
G +LL L+ A A + HSL+Y +S+ G + F++ G++D F+R+D
Sbjct: 4 GTLLLLLSEALALTQTWAGS--HSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDA 61
Query: 64 R--RAKPQGQWAENVLGAKTWDTETEDLTENGQDLR---RTLTHIKDQ-KGGLHSLQEIR 117
R P+ W E G++ WD ET + Q R RTL +Q + G H+LQ +
Sbjct: 62 ASPRMVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
Query: 118 VCEIHEDSS-TRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKT 176
CE+ D RG F YDG+ +L+ N + + T A A ++ DA +
Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWT------AVDTAAQISEQKSNDASEA 174
Query: 177 KTHYRAMQADCLQKLQRYLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNI 235
+ ++ C++ L +YL+ G + PP +VT +S+ T+ C A FYP I
Sbjct: 175 EHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEI 234
Query: 236 TLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
TLTW+QDG + +T + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 235 TLTWQQDGEGHTQDT-ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 286
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 140 bits (354), Expect = 1e-33
Identities = 92/290 (31%), Positives = 147/290 (50%), Gaps = 23/290 (7%)
Query: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTE 85
HSL Y M S+ S F A G++D Q F+ YD + RR +P+ W + + ++ W
Sbjct: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQL 87
Query: 86 TEDL-------TENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGE 138
++ L T + + H K+ H+LQ I CE+ ED+ST G + YDG+
Sbjct: 88 SQSLKGWDHMFTVDFWTIMENHNHSKES----HTLQVILGCEMQEDNSTEGYWKYGYDGQ 143
Query: 139 LFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSG 198
+LE T+ + A+ A W+ ++ + + ++ DC +LQ+ L+ G
Sbjct: 144 ----DHLEFCPDTLDWRA-AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELG 198
Query: 199 VAIR-RTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVL 257
+ + VPP+V VT V+ T+ CRA ++YP+NIT+ W +D + + DVL
Sbjct: 199 RGVLDQQVPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVL 257
Query: 258 PDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
P+G+GTYQ W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 258 PNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 307
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 140 bits (353), Expect = 2e-33
Identities = 97/342 (28%), Positives = 165/342 (48%), Gaps = 28/342 (8%)
Query: 11 AVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--RAKP 68
A + P PP + HSLRY +S+ G + F++ G++D F+R+D R +P
Sbjct: 29 ARSHPSPPPGS----HSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEP 84
Query: 69 QGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIK----DQKGGLHSLQEIRVCEIHED 124
+ W E G + WD +T + + Q R L ++ + G H+LQ + C++ D
Sbjct: 85 RAPWMEQE-GPEYWDEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPD 143
Query: 125 SS-TRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAM 183
RG YDG +++ N + + T A A +T +E A + +
Sbjct: 144 GRFLRGFMQDAYDGRDYIALNEDLRSWT------AADTAAQITKRKREAAGAAERQRNYL 197
Query: 184 QADCLQKLQRYLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQD 242
+ C++ L+RYL++G A+ R PP +VT +SE +T+ C A FYP I+LTW+++
Sbjct: 198 EGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQRE 257
Query: 243 GVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALV 302
G + + + + P G+GT+Q W A + GEEQR+TC ++H G + L
Sbjct: 258 GEDQTQD-MELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEG------LQEPLTLR 310
Query: 303 LQSQRTDFPYVSAAMPCFVIIIILCVPCC--KKKTSAAEGPE 342
+ +T F + + ++++ L +KK S EG E
Sbjct: 311 WEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGREGRE 352
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 138 bits (348), Expect = 7e-33
Identities = 94/332 (28%), Positives = 163/332 (49%), Gaps = 33/332 (9%)
Query: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--RAKPQGQWAENVLGAKTWD 83
HS+RY +S+ G + F++ G++D F+R+D R +P+ W E G + WD
Sbjct: 27 HSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQE-GPEYWD 85
Query: 84 TETEDLTENGQDLRRTLTHIK----DQKGGLHSLQEIRVCEIHEDSST-RGSRHFYYDGE 138
ET+ Q R +L +++ + G H+LQ + C++ D RG YDG+
Sbjct: 86 RETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGK 145
Query: 139 LFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSG 198
+++ N + + T A A +T E A + ++ C++ L+RYL++G
Sbjct: 146 DYIALNEDLRSWT------AADTAAQITQRKLEAARAAEQLRAYLEGTCVEWLRRYLENG 199
Query: 199 V-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVL 257
++R PP +VT +S+ T+ C A FYP ITLTW++DG + +T + +
Sbjct: 200 KETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDT-ELVETR 258
Query: 258 PDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVS--- 314
P G+GT+Q W A + G+EQR+TC+M+H G + L L + + P +
Sbjct: 259 PAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQ--------EPLTLSWEPSSQPTIPIMG 310
Query: 315 --AAMPCFVIIIIL----CVPCCKKKTSAAEG 340
A + V++ +L C++K+S +G
Sbjct: 311 IVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKG 342
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 137 bits (346), Expect = 1e-32
Identities = 88/284 (30%), Positives = 145/284 (51%), Gaps = 23/284 (8%)
Query: 32 LMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDL-- 89
L++L Q +Q L G++D Q F+ YD + RR +P+ W + + ++ W ++ L
Sbjct: 11 LLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKG 70
Query: 90 -----TENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQN 144
T + + H K+ H+LQ I CE+ ED+ST G + YDG+ +
Sbjct: 71 WDHMFTVDFWTIMENHNHSKES----HTLQVILGCEMQEDNSTEGYWKYGYDGQ----DH 122
Query: 145 LETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIR-R 203
LE T+ + A+ A W+ ++ + + ++ DC +LQ+ L+ G + +
Sbjct: 123 LEFCPDTLDWRA-AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQ 181
Query: 204 TVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGT 263
VPP+V VT V+ T+ CRA ++YP+NIT+ W +D + + DVLP+G+GT
Sbjct: 182 QVPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 240
Query: 264 YQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
YQ W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 241 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 284
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 137 bits (345), Expect = 2e-32
Identities = 89/276 (32%), Positives = 143/276 (51%), Gaps = 20/276 (7%)
Query: 23 AEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--RAKPQGQWAENVLGAK 80
A HSLRY +S+ G + ++A ++D FLR+D R +P+ W E G +
Sbjct: 21 AGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQ 79
Query: 81 TWDTETEDLTENGQD----LRRTLTHIKDQKGGLHSLQEIRVCEIHEDSST-RGSRHFYY 135
W+ T N Q LR L + G H+LQ + C++ D RG Y
Sbjct: 80 YWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAY 139
Query: 136 DGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWK--EDAMKTKTHYRAMQADCLQKLQR 193
DG+ ++S N + + T A T+A F++ E A + +T+ ++ +CL+ L+R
Sbjct: 140 DGKDYISLNEDLRSWTA-----ADTVAQITQRFYEAEEYAEEFRTY---LEGECLELLRR 191
Query: 194 YLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQ 252
YL++G ++R PP +V +S+ T+ C A FYP ITLTW++DG + +T +
Sbjct: 192 YLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDT-E 250
Query: 253 WGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
+ P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 251 LVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEG 286
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 137 bits (345), Expect = 2e-32
Identities = 89/276 (32%), Positives = 143/276 (51%), Gaps = 20/276 (7%)
Query: 23 AEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--RAKPQGQWAENVLGAK 80
A HSLRY +S+ G + ++A ++D FLR+D R +P+ W E G +
Sbjct: 21 AGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQ 79
Query: 81 TWDTETEDLTENGQD----LRRTLTHIKDQKGGLHSLQEIRVCEIHEDSST-RGSRHFYY 135
W+ T N Q LR L + G H+LQ + C++ D RG Y
Sbjct: 80 YWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAY 139
Query: 136 DGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWK--EDAMKTKTHYRAMQADCLQKLQR 193
DG+ ++S N + + T A T+A F++ E A + +T+ ++ +CL+ L+R
Sbjct: 140 DGKDYISLNEDLRSWTA-----ADTVAQITQRFYEAEEYAEEFRTY---LEGECLELLRR 191
Query: 194 YLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQ 252
YL++G ++R PP +V +S+ T+ C A FYP ITLTW++DG + +T +
Sbjct: 192 YLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDT-E 250
Query: 253 WGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
+ P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 251 LVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEG 286
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 134 bits (338), Expect = 1e-31
Identities = 85/306 (27%), Positives = 141/306 (46%), Gaps = 21/306 (6%)
Query: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTE 85
HSLRY + +S F++ G++D P YD R+ +P+ W L W+
Sbjct: 25 HSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERY 84
Query: 86 TEDLTENGQ----DLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFL 141
T+ L Q +L+R H G H+ Q + CE+ ED ST G + YDG+ FL
Sbjct: 85 TQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFL 142
Query: 142 SQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGV-A 200
N +T +A + W+ + + ++ +C+ L+R+L+ G
Sbjct: 143 IFNKDTLSWLA-----VDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDT 197
Query: 201 IRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDG 260
++RT PP+V V E G + C+A FYP I +TW ++G + +GD+LP G
Sbjct: 198 LQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEID-YGDILPSG 256
Query: 261 NGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCF 320
+GTYQ W + + ++C++EH G H VP + P V A+
Sbjct: 257 DGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVP--------QESETIPLVMKAVSGS 308
Query: 321 VIIIIL 326
++++I+
Sbjct: 309 IVLVIV 314
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 131 bits (329), Expect = 1e-30
Identities = 87/293 (29%), Positives = 143/293 (48%), Gaps = 24/293 (8%)
Query: 8 LFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--R 65
LFL ++ A HS+RY +S+ G + F+A G++D F+R+D R
Sbjct: 9 LFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACPR 68
Query: 66 AKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIK----DQKGGLHSLQEIRVCEI 121
+P+ W E G + W+ ET + + Q R L ++ + H+LQ + C++
Sbjct: 69 MEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCDL 127
Query: 122 HEDSST-RGSRHFYYDGELFLSQNLE----TQESTVPQSSRAQTLAMNVTNFWKEDAMKT 176
D RG + YDG+ +L+ N + T T Q S+ + A NV
Sbjct: 128 GSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVA---------- 177
Query: 177 KTHYRAMQADCLQKLQRYLKSGVA-IRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNI 235
+ ++ C++ L RYL++G ++R PP +VT V + T+ C A FYP I
Sbjct: 178 EQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEI 237
Query: 236 TLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
LTW++DG + + + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 238 ILTWQRDGEDQTQDVELV-ETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 289
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 127 bits (319), Expect = 2e-29
Identities = 85/289 (29%), Positives = 139/289 (48%), Gaps = 35/289 (12%)
Query: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTE 85
HSL Y M S+ S F A G++D Q F+ YD + RR +P+ W + + ++ W
Sbjct: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQL 87
Query: 86 TEDL-------TENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGE 138
++ L T + + H K+ H+LQ I CE+ ED+ST G + YDG+
Sbjct: 88 SQSLKGWDHMFTVDFWTIMENHNHSKES----HTLQVILGCEMQEDNSTEGYWKYGYDGQ 143
Query: 139 LFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSG 198
+LE T+ + A+ A W+ ++ + + ++ DC +LQ+ L+ G
Sbjct: 144 ----DHLEFCPDTLDWRA-AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELG 198
Query: 199 VAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLP 258
+ + + T+ CRA ++YP+NIT+ W +D + + DVLP
Sbjct: 199 RGV--------------LDQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLP 244
Query: 259 DGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
+G+GTYQ W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 245 NGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 293
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 113 bits (282), Expect = 3e-25
Identities = 68/198 (34%), Positives = 107/198 (54%), Gaps = 12/198 (6%)
Query: 111 HSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWK 170
H+LQ I CE+ ED+ST G + YDG+ +LE T+ + A+ A W+
Sbjct: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQ----DHLEFCPDTLDWRA-AEPRAWPTKLEWE 82
Query: 171 EDAMKTKTHYRAMQADCLQKLQRYLKSGVAIR-RTVPPMVNVTCSEVSEGNITVTCRASS 229
++ + + ++ DC +LQ+ L+ G + + VPP+V VT V+ T+ CRA +
Sbjct: 83 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRALN 141
Query: 230 FYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGN 289
+YP+NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+TC +EH G
Sbjct: 142 YYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL 201
Query: 290 HGT-----HPVPSGKALV 302
P PSG ++
Sbjct: 202 DQPLIVIWEPSPSGTLVI 219
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 104 bits (260), Expect = 1e-22
Identities = 80/286 (27%), Positives = 127/286 (44%), Gaps = 12/286 (4%)
Query: 6 VLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRR 65
+L L + P P +SL Y LS+ F A G L+ F RY+ + R+
Sbjct: 8 LLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRK 67
Query: 66 AKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKD---QKGGLHSLQEIRVCEIH 122
++P G W + V G + W +++ TL I + G H LQ CEI
Sbjct: 68 SQPMGLWRQ-VEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIE 126
Query: 123 EDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRA 182
+ S+ +YYDG+ ++ N E + VP AQ W+ + + +
Sbjct: 127 NNRSSGAFWKYYYDGKDYIEFNKEIP-AWVPFDPAAQITKQK----WEAEPVYVQRAKAY 181
Query: 183 MQADCLQKLQRYLK-SGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQ 241
++ +C L++YLK S + R PP V VT + + C A FYP I + W +
Sbjct: 182 LEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTR 241
Query: 242 DGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHS 287
G + GDVL +GNGTYQ+WV + + ++C+++HS
Sbjct: 242 AGEVQEPELR--GDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHS 285
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 99.8 bits (247), Expect = 4e-21
Identities = 61/197 (30%), Positives = 99/197 (50%), Gaps = 24/197 (12%)
Query: 111 HSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWK 170
H+LQ I CE+ ED+ST G + YDG+ +LE T+ + A+ A W+
Sbjct: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQ----DHLEFCPDTLDWRA-AEPRAWPTKLEWE 82
Query: 171 EDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSF 230
++ + + ++ DC +LQ+ L+ G + + + T+ CRA ++
Sbjct: 83 RHKIRARQNRAYLERDCPAQLQQLLELGRGV--------------LDQQVTTLRCRALNY 128
Query: 231 YPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNH 290
YP+NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+TC +EH G
Sbjct: 129 YPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLD 188
Query: 291 GT-----HPVPSGKALV 302
P PSG ++
Sbjct: 189 QPLIVIWEPSPSGTLVI 205
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 88.2 bits (217), Expect = 1e-17
Identities = 72/287 (25%), Positives = 130/287 (45%), Gaps = 22/287 (7%)
Query: 6 VLLFLAVAFPFAPPAAAAEPH-SLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR 64
+LLFL P + AE H SL Y+L +S F G L Q +L Y+ +
Sbjct: 13 LLLFLL------PGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG 66
Query: 65 RAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHED 124
A+P G W + W+ ET DL + + + G ++LQ + CE+ D
Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGK--GPYTLQGLLGCELGPD 124
Query: 125 SSTRGSRHFYYDGELFLSQNLE--TQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRA 182
+++ + F +GE F++ +L+ T P+ A+ ++ W++
Sbjct: 125 NTSVPTAKFALNGEEFMNFDLKQGTWGGDWPE-------ALAISQRWQQQDKAANKELTF 177
Query: 183 MQADCLQKLQRYLKSGVA-IRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQ 241
+ C +L+ +L+ G + PP + + S G +TC A SFYP + L + +
Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
Query: 242 DGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
+G L+ T Q GD P+ +G++ + ++ G+E + C ++H+G
Sbjct: 238 NG--LAAGTGQ-GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG 281
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 88.2 bits (217), Expect = 1e-17
Identities = 72/287 (25%), Positives = 130/287 (45%), Gaps = 22/287 (7%)
Query: 6 VLLFLAVAFPFAPPAAAAEPH-SLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR 64
+LLFL P + AE H SL Y+L +S F G L Q +L Y+ +
Sbjct: 13 LLLFLL------PGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG 66
Query: 65 RAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHED 124
A+P G W + W+ ET DL + + + G ++LQ + CE+ D
Sbjct: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGK--GPYTLQGLLGCELGPD 124
Query: 125 SSTRGSRHFYYDGELFLSQNLE--TQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRA 182
+++ + F +GE F++ +L+ T P+ A+ ++ W++
Sbjct: 125 NTSVPTAKFALNGEEFMNFDLKQGTWGGDWPE-------ALAISQRWQQQDKAANKELTF 177
Query: 183 MQADCLQKLQRYLKSGVA-IRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQ 241
+ C +L+ +L+ G + PP + + S G +TC A SFYP + L + +
Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
Query: 242 DGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
+G L+ T Q GD P+ +G++ + ++ G+E + C ++H+G
Sbjct: 238 NG--LAAGTGQ-GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG 281
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 83.2 bits (204), Expect = 4e-16
Identities = 42/103 (40%), Positives = 60/103 (58%), Gaps = 6/103 (5%)
Query: 205 VPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTY 264
VPP+V VT V+ T+ CRA ++YP+NIT+ W +D + + DVLP+G+GTY
Sbjct: 114 VPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 172
Query: 265 QTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
Q W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 173 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 215
Score = 42.0 bits (97), Expect = 0.001
Identities = 20/57 (35%), Positives = 31/57 (54%)
Query: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTW 82
HSL Y M S+ S F A G++D Q F+ YD + RR +P+ W + + ++ W
Sbjct: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMW 84
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 82.8 bits (203), Expect = 5e-16
Identities = 42/106 (39%), Positives = 61/106 (57%), Gaps = 6/106 (5%)
Query: 202 RRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGN 261
R +PP+V VT V+ T+ CRA ++YP+NIT+ W +D + + DVLP+G+
Sbjct: 23 RLLLPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 81
Query: 262 GTYQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
GTYQ W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 82 GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 127
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 75.1 bits (183), Expect = 1e-13
Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 5/86 (5%)
Query: 222 TVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFT 281
T+ CRA ++YP+NIT+ W +D + + DVLP+G+GTYQ W+ + GEEQR+T
Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
Query: 282 CYMEHSGNHGT-----HPVPSGKALV 302
C +EH G P PSG ++
Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTLVI 201
Score = 42.0 bits (97), Expect = 0.001
Identities = 20/57 (35%), Positives = 31/57 (54%)
Query: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTW 82
HSL Y M S+ S F A G++D Q F+ YD + RR +P+ W + + ++ W
Sbjct: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMW 84
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 69.3 bits (168), Expect = 5e-12
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 18/185 (9%)
Query: 23 AEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--RAKPQGQWAENVLGAK 80
A HSLRY +S+ G + ++A ++D FLR+D R +P+ W E G +
Sbjct: 21 AGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQ 79
Query: 81 TWDTETEDLTENGQD----LRRTLTHIKDQKGGLHSLQEIRVCEIHEDSS-TRGSRHFYY 135
W+ T N Q LR L + G H+LQ + C++ D RG Y
Sbjct: 80 YWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAY 139
Query: 136 DGELFLSQNLETQESTVPQSSRAQTLAMNVTNFW--KEDAMKTKTHYRAMQADCLQKLQR 193
DG+ ++S N + + T A T+A F+ +E A + +T+ ++ +CL+ L+R
Sbjct: 140 DGKDYISLNEDLRSWTA-----ADTVAQITQRFYEAEEYAEEFRTY---LEGECLELLRR 191
Query: 194 YLKSG 198
YL++G
Sbjct: 192 YLENG 196
>gi|13375656 UL16 binding protein 3 [Homo sapiens]
Length = 244
Score = 60.5 bits (145), Expect = 3e-09
Identities = 49/176 (27%), Positives = 72/176 (40%), Gaps = 8/176 (4%)
Query: 23 AEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTW 82
A+ HSL YN ++ Q + +D + FL YD + G E + W
Sbjct: 29 ADAHSLWYNFTIIHLPRHGQQWCEVQSQVDQKNFLSYDCGSDKVLSMGHLEEQLYATDAW 88
Query: 83 DTETEDLTENGQDLRRTL--THIKD-QKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGEL 139
+ E L E GQ LR L T ++D G +LQ CE D RGS F +DG
Sbjct: 89 GKQLEMLREVGQRLRLELADTELEDFTPSGPLTLQVRMSCECEADGYIRGSWQFSFDGRK 148
Query: 140 FLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYL 195
FL + ++ TV + A + W++D+ T DC L+ +L
Sbjct: 149 FLLFDSNNRKWTVVHAG-----ARRMKEKWEKDSGLTTFFKMVSMRDCKSWLRDFL 199
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 58.2 bits (139), Expect = 1e-08
Identities = 47/178 (26%), Positives = 80/178 (44%), Gaps = 13/178 (7%)
Query: 119 CEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKT 178
CE+H S G ++G LS T + S AQ++ ++ N E T+T
Sbjct: 120 CELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVC-HLLNHQYEGV--TET 176
Query: 179 HYRAMQADCLQKLQRYLKSG-VAIRRTVPPMVNVTCS-EVSEGNITVTCRASSFYPRNIT 236
Y +++ C + L L +G + + R V P ++ + G + + C AS FYP+ +
Sbjct: 177 VYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVW 236
Query: 237 LTW---RQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHG 291
+TW Q+ + H GD+LP+ +GT+ V + E +C + HS G
Sbjct: 237 VTWMRNEQEQLGTKH-----GDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGG 289
>gi|21040249 retinoic acid early transcript 1E [Homo sapiens]
Length = 263
Score = 56.2 bits (134), Expect = 5e-08
Identities = 51/189 (26%), Positives = 73/189 (38%), Gaps = 7/189 (3%)
Query: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTE 85
HSL +N + S Q A+ L+ FL+Y+ KP G + V TW
Sbjct: 31 HSLCFNFTIKSLSRPGQPWCEAQVFLNKNLFLQYNSDNNMVKPLGLLGKKVYATSTWGEL 90
Query: 86 TEDLTENGQDLRRTLTHIKDQ--KGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQ 143
T+ L E G+DLR L IK Q +LQ C+ + T S F +GE L
Sbjct: 91 TQTLGEVGRDLRMLLCDIKPQIKTSDPSTLQVEMFCQREAERCTGASWQFATNGEKSLLF 150
Query: 144 NLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRR 203
+ TV A + WK+D K + + DC L+ +L A+
Sbjct: 151 DAMNMTWTVINHE-----ASKIKETWKKDRGLEKYFRKLSKGDCDHWLREFLGHWEAMPE 205
Query: 204 TVPPMVNVT 212
VN +
Sbjct: 206 PTVSPVNAS 214
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 53.5 bits (127), Expect = 3e-07
Identities = 45/181 (24%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Query: 113 LQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKED 172
LQ CE+H +++ H + G+ LS + E T ++ LA+ V N +D
Sbjct: 114 LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPT-QEAPLWVNLAIQVLN---QD 169
Query: 173 AMKTKTHYRAMQADCLQKLQRYLKSGVA-IRRTVPPMVNVTCS-EVSEGNITVTCRASSF 230
+T + C Q + L+SG + +++ V P ++ G + + C S F
Sbjct: 170 KWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGF 229
Query: 231 YPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNH 290
YP+ + + W + G TQ GD+LP+ + T+ + GE +C ++HS
Sbjct: 230 YPKPVWVKWMR-GEQEQQGTQP-GDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLE 287
Query: 291 G 291
G
Sbjct: 288 G 288
>gi|18426911 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 51.2 bits (121), Expect = 2e-06
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 205 VPPMVNVTCSEV-SEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGT 263
VPP + VT V +E + VTC+ FYP+ + LTW ++G T DG
Sbjct: 252 VPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYN 311
Query: 264 YQTWVATRI-RQGEEQRFTCYMEHSG 288
+ +W+ + ++ + TC +EH G
Sbjct: 312 WMSWLLVNVSAHRDDVKLTCQVEHDG 337
Score = 31.2 bits (69), Expect = 1.6
Identities = 14/49 (28%), Positives = 24/49 (48%)
Query: 199 VAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLS 247
V + + P + + ++ TC + F PR+ITL W ++G LS
Sbjct: 144 VRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELS 192
>gi|91105767 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 51.2 bits (121), Expect = 2e-06
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 205 VPPMVNVTCSEV-SEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGT 263
VPP + VT V +E + VTC+ FYP+ + LTW ++G T DG
Sbjct: 252 VPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYN 311
Query: 264 YQTWVATRI-RQGEEQRFTCYMEHSG 288
+ +W+ + ++ + TC +EH G
Sbjct: 312 WMSWLLVNVSAHRDDVKLTCQVEHDG 337
Score = 31.2 bits (69), Expect = 1.6
Identities = 14/49 (28%), Positives = 24/49 (48%)
Query: 199 VAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLS 247
V + + P + + ++ TC + F PR+ITL W ++G LS
Sbjct: 144 VRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELS 192
>gi|91105764 signal-regulatory protein alpha precursor [Homo
sapiens]
Length = 504
Score = 51.2 bits (121), Expect = 2e-06
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 205 VPPMVNVTCSEV-SEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGT 263
VPP + VT V +E + VTC+ FYP+ + LTW ++G T DG
Sbjct: 252 VPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTVTENKDGTYN 311
Query: 264 YQTWVATRI-RQGEEQRFTCYMEHSG 288
+ +W+ + ++ + TC +EH G
Sbjct: 312 WMSWLLVNVSAHRDDVKLTCQVEHDG 337
Score = 31.2 bits (69), Expect = 1.6
Identities = 14/49 (28%), Positives = 24/49 (48%)
Query: 199 VAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLS 247
V + + P + + ++ TC + F PR+ITL W ++G LS
Sbjct: 144 VRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELS 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,114,538
Number of Sequences: 37866
Number of extensions: 667122
Number of successful extensions: 1923
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 1761
Number of HSP's gapped (non-prelim): 120
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.