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Search of human proteins with 110618227
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110618227 CD1C antigen precursor [Homo sapiens]
(333 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110618227 CD1C antigen precursor [Homo sapiens] 696 0.0
gi|4502645 CD1B antigen precursor [Homo sapiens] 402 e-112
gi|110618224 CD1A antigen precursor [Homo sapiens] 390 e-109
gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] 345 2e-95
gi|110618230 CD1E antigen isoform b precursor [Homo sapiens] 341 5e-94
gi|4502649 CD1D antigen precursor [Homo sapiens] 325 3e-89
gi|110618232 CD1E antigen isoform c precursor [Homo sapiens] 281 6e-76
gi|110618234 CD1E antigen isoform d precursor [Homo sapiens] 246 2e-65
gi|110618236 CD1E antigen isoform e precursor [Homo sapiens] 163 2e-40
gi|110618238 CD1E antigen isoform f precursor [Homo sapiens] 103 3e-22
gi|4504417 major histocompatibility complex, class I-related [Ho... 79 4e-15
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 75 1e-13
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 73 4e-13
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 70 2e-12
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 70 2e-12
gi|4504415 major histocompatibility complex, class I, G precurso... 69 4e-12
gi|149158702 major histocompatibility complex, class I, F isofor... 68 1e-11
gi|149158698 major histocompatibility complex, class I, F isofor... 68 1e-11
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 67 2e-11
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 65 6e-11
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 65 6e-11
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 65 1e-10
gi|52630342 major histocompatibility complex, class I, C precurs... 64 1e-10
gi|24797067 major histocompatibility complex, class I, A precurs... 64 2e-10
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 62 9e-10
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 59 8e-09
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 58 1e-08
gi|62912479 major histocompatibility complex, class I, E precurs... 58 1e-08
gi|17986001 major histocompatibility complex, class I, B precurs... 56 5e-08
gi|24797076 major histocompatibility complex, class II, DP beta ... 55 7e-08
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 696 bits (1797), Expect = 0.0
Identities = 333/333 (100%), Positives = 333/333 (100%)
Query: 1 MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS 60
MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS
Sbjct: 1 MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS 60
Query: 61 ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC 120
ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC
Sbjct: 61 ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC 120
Query: 121 ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNL 180
ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNL
Sbjct: 121 ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNL 180
Query: 181 IRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWM 240
IRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWM
Sbjct: 181 IRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWM 240
Query: 241 RNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF 300
RNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF
Sbjct: 241 RNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF 300
Query: 301 SMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL 333
SMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL
Sbjct: 301 SMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL 333
>gi|4502645 CD1B antigen precursor [Homo sapiens]
Length = 333
Score = 402 bits (1032), Expect = e-112
Identities = 201/333 (60%), Positives = 245/333 (73%), Gaps = 2/333 (0%)
Query: 1 MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS 60
ML L F LLA+L PGG++ A Q SFHVIQ SF N +WA+ QGSGWLD+LQ HGWDS
Sbjct: 1 MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDS 60
Query: 61 ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC 120
+SGT IFL WSKGNFS++E+++LE +FR Y+FG RE+QD A KYPFE+Q AGC
Sbjct: 61 DSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGC 120
Query: 121 ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNL 180
ELHSG + F + A GLD LS +N + VPSP GS AQ C L+ QY+G+ ETV L
Sbjct: 121 ELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALII-QYQGIMETVRIL 179
Query: 181 IRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWM 240
+ TCPR+LLG+L+AGK + RQV+PEAWLSS PS G G+L LVCH SGFYPKPVWV WM
Sbjct: 180 LYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWM 239
Query: 241 RNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF 300
R EQEQ GT+ GDILPNA+ TWYL+ L+VA E AGLSCRV+HSSL GQDIILYW +
Sbjct: 240 RGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPT 299
Query: 301 SMNWIALVVIVP-LVILIVLVLWFKKHCSYQDI 332
S+ I L +IVP L++L+ L LW+ + SYQ+I
Sbjct: 300 SIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNI 332
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 390 bits (1003), Expect = e-109
Identities = 192/327 (58%), Positives = 233/327 (71%), Gaps = 2/327 (0%)
Query: 1 MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS 60
MLFL LLA+L PG NAD +E +SFHV I SF N SW + SGWL +LQTH WDS
Sbjct: 1 MLFLLLPLLAVL-PGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDS 59
Query: 61 ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC 120
S TI+FL WS+GNFSNEE +LE LFR I+ +A + +YPFE+QV GC
Sbjct: 60 NSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC 119
Query: 121 ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNL 180
ELHSGK F Q+A+ G D +SFQN +W+P P G++A+ C +LN Q + + +NL
Sbjct: 120 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLN-QNQHENDITHNL 178
Query: 181 IRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWM 240
+ TCPRF+LGLLDAGK ++ RQV+PEAWLS PS G G L LVCH SGFYPKPVWV WM
Sbjct: 179 LSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWM 238
Query: 241 RNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF 300
R EQEQ GT+ GDILP+ADGTWYL+ LEVA+ E A LSCRV+HSSL GQDI+LYW HH
Sbjct: 239 RGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHS 298
Query: 301 SMNWIALVVIVPLVILIVLVLWFKKHC 327
S+ +I L VIVPL++LI L LWF+K C
Sbjct: 299 SVGFIILAVIVPLLLLIGLALWFRKRC 325
>gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
Length = 388
Score = 345 bits (886), Expect = 2e-95
Identities = 175/343 (51%), Positives = 230/343 (67%), Gaps = 14/343 (4%)
Query: 1 MLFLQFLLLALLLPGGDNAD---------ASQEHVSFHVIQIFSFVNQSWARGQGSGWLD 51
ML L L L PG + A A++E +SF ++Q SF N SWA +GSGWL
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 52 ELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYP 111
+LQTHGWD+ GTI FL WS GNFS +EL +L+ LF+ Y + +Q A Q +YP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 112 FEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYE 171
FE+Q+ AGC +++ P+ F +A+ G D LSFQ +W PSPG G AQ++C +LN +Y
Sbjct: 121 FEIQILAGCRMNA---PQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLN-RYL 176
Query: 172 GVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFY 231
+ E + +L+ TCPRFL GL++AG+ + R+V+PEAWLS PS G G+L LVCH SGFY
Sbjct: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
Query: 232 PKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQD 291
PKPVWV WMR EQEQ GT+ GD+LPNAD TWYL+ L+VA+ E AGLSCRV+HSSLGG D
Sbjct: 237 PKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHD 296
Query: 292 IILYW-GHHFSMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL 333
+I++W G+ + I L VIV LVIL+V+ KK S ++IL
Sbjct: 297 LIIHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNIL 339
>gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]
Length = 376
Score = 341 bits (875), Expect = 5e-94
Identities = 172/335 (51%), Positives = 225/335 (67%), Gaps = 14/335 (4%)
Query: 1 MLFLQFLLLALLLPGGDNAD---------ASQEHVSFHVIQIFSFVNQSWARGQGSGWLD 51
ML L L L PG + A A++E +SF ++Q SF N SWA +GSGWL
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 52 ELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYP 111
+LQTHGWD+ GTI FL WS GNFS +EL +L+ LF+ Y + +Q A Q +YP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 112 FEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYE 171
FE+Q+ AGC +++ P+ F +A+ G D LSFQ +W PSPG G AQ++C +LN +Y
Sbjct: 121 FEIQILAGCRMNA---PQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLN-RYL 176
Query: 172 GVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFY 231
+ E + +L+ TCPRFL GL++AG+ + R+V+PEAWLS PS G G+L LVCH SGFY
Sbjct: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
Query: 232 PKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQD 291
PKPVWV WMR EQEQ GT+ GD+LPNAD TWYL+ L+VA+ E AGLSCRV+HSSLGG D
Sbjct: 237 PKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHD 296
Query: 292 IILYW-GHHFSMNWIALVVIVPLVILIVLVLWFKK 325
+I++W G+ + I L VIV LVIL+V+ KK
Sbjct: 297 LIIHWGGYSIFLILICLTVIVTLVILVVVDSRLKK 331
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 325 bits (833), Expect = 3e-89
Identities = 166/333 (49%), Positives = 214/333 (64%), Gaps = 4/333 (1%)
Query: 4 LQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDSESG 63
L FLLL LL +A+ Q +QI SF N SW R G WL ELQTH W ++S
Sbjct: 4 LLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSD 63
Query: 64 TIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGCELH 123
T+ L WS+G FS+++ L+ +FR Y TR++++ A YP E+QV AGCE+H
Sbjct: 64 TVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVH 123
Query: 124 SGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNLIRS 183
G + FF VAF G D+LSFQ T+W P+ +LN Q + ETV L+
Sbjct: 124 PGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLN-QDKWTRETVQWLLNG 182
Query: 184 TCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWMRNE 243
TCP+F+ GLL++GK + +QV+P+AWLS PS G G+LLLVCH SGFYPKPVWV WMR E
Sbjct: 183 TCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGE 242
Query: 244 QEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF-SM 302
QEQ GT+ GDILPNAD TWYL+ L+V + E AGLSCRV+HSSL GQDI+LYWG + SM
Sbjct: 243 QEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSM 302
Query: 303 NWIALVVIVPLVILIVL--VLWFKKHCSYQDIL 333
IAL V+ L+ L+++ FK+ SYQ +L
Sbjct: 303 GLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL 335
>gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]
Length = 290
Score = 281 bits (719), Expect = 6e-76
Identities = 137/273 (50%), Positives = 181/273 (66%), Gaps = 13/273 (4%)
Query: 1 MLFLQFLLLALLLPGGDNAD---------ASQEHVSFHVIQIFSFVNQSWARGQGSGWLD 51
ML L L L PG + A A++E +SF ++Q SF N SWA +GSGWL
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 52 ELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYP 111
+LQTHGWD+ GTI FL WS GNFS +EL +L+ LF+ Y + +Q A Q +YP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 112 FEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYE 171
FE+Q+ AGC +++ P+ F +A+ G D LSFQ +W PSPG G AQ++C +LN +Y
Sbjct: 121 FEIQILAGCRMNA---PQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLN-RYL 176
Query: 172 GVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFY 231
+ E + +L+ TCPRFL GL++AG+ + R+V+PEAWLS PS G G+L LVCH SGFY
Sbjct: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
Query: 232 PKPVWVTWMRNEQEQLGTKHGDILPNADGTWYL 264
PKPVWV WMR EQEQ GT+ GD+LPNAD TW++
Sbjct: 237 PKPVWVMWMRGEQEQRGTQRGDVLPNADETWWI 269
>gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]
Length = 321
Score = 246 bits (629), Expect = 2e-65
Identities = 122/250 (48%), Positives = 162/250 (64%), Gaps = 13/250 (5%)
Query: 1 MLFLQFLLLALLLPGGDNAD---------ASQEHVSFHVIQIFSFVNQSWARGQGSGWLD 51
ML L L L PG + A A++E +SF ++Q SF N SWA +GSGWL
Sbjct: 1 MLLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLG 60
Query: 52 ELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYP 111
+LQTHGWD+ GTI FL WS GNFS +EL +L+ LF+ Y + +Q A Q +YP
Sbjct: 61 DLQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYP 120
Query: 112 FEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYE 171
FE+Q+ AGC ++ +P+ F +A+ G D LSFQ +W PSPG G AQ++C +LN +Y
Sbjct: 121 FEIQILAGCRMN---APQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLN-RYL 176
Query: 172 GVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFY 231
+ E + +L+ TCPRFL GL++AG+ + R+V+PEAWLS PS G G+L LVCH SGFY
Sbjct: 177 DIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFY 236
Query: 232 PKPVWVTWMR 241
PKPVWV WMR
Sbjct: 237 PKPVWVMWMR 246
>gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]
Length = 187
Score = 163 bits (412), Expect = 2e-40
Identities = 79/123 (64%), Positives = 94/123 (76%), Gaps = 1/123 (0%)
Query: 204 VRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWMRNEQEQLGTKHGDILPNADGTWY 263
V+PEAWLS PS G G+L LVCH SGFYPKPVWV WMR EQEQ GT+ GD+LPNAD TWY
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
Query: 264 LQVILEVASEEPAGLSCRVRHSSLGGQDIILYW-GHHFSMNWIALVVIVPLVILIVLVLW 322
L+ L+VA+ E AGLSCRV+HSSLGG D+I++W G+ + I L VIV LVIL+V+
Sbjct: 80 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 139
Query: 323 FKK 325
KK
Sbjct: 140 LKK 142
>gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]
Length = 101
Score = 103 bits (256), Expect = 3e-22
Identities = 44/61 (72%), Positives = 50/61 (81%)
Query: 204 VRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWMRNEQEQLGTKHGDILPNADGTWY 263
V+PEAWLS PS G G+L LVCH SGFYPKPVWV WMR EQEQ GT+ GD+LPNAD TW+
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWW 79
Query: 264 L 264
+
Sbjct: 80 I 80
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 79.3 bits (194), Expect = 4e-15
Identities = 60/204 (29%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 87 LFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQN 146
+F+ L L R S Y + GCEL S GF Q A++G D L F
Sbjct: 94 MFKVELKRLQRHYNHSGSHTYQRM-------IGCELLEDGSTTGFLQYAYDGQDFLIFNK 146
Query: 147 TT--WVPSPGCGSLAQSVCHLLNHQYEGVT-ETVY--NLIRSTCPRFLLGLLDAGKMYVH 201
T W+ +V H + +E E +Y N + C +L L+ GK +
Sbjct: 147 DTLSWLA-------VDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQ 199
Query: 202 RQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWMRNEQEQL-GTKHGDILPNADG 260
R P ++ + + G L C A GFYP +++TWM+N +E + +GDILP+ DG
Sbjct: 200 RTEPPLVRVNRKETF-PGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDG 258
Query: 261 TWYLQVILEVASEEPAGLSCRVRH 284
T+ +E+ + SC V H
Sbjct: 259 TYQAWASIELDPQSSNLYSCHVEH 282
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 74.7 bits (182), Expect = 1e-13
Identities = 60/223 (26%), Positives = 106/223 (47%), Gaps = 21/223 (9%)
Query: 114 VQVKAGCELH-SGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQY 170
+Q+ GC++ G+ GF Q A++G D ++ +W + + + +
Sbjct: 132 LQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQITKR-----KREA 186
Query: 171 EGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGF 230
G E N + C L L+ GK + R P+A ++ P + ++ L C A GF
Sbjct: 187 AGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHP-ISEREVTLRCWALGF 245
Query: 231 YPKPVWVTWMRNEQEQLGTKHGDIL---PNADGTWYLQVILEVASEEPAGLSCRVRHSSL 287
YP+ + +TW R ++Q T+ +++ P+ DGT+ L V S E +CRV+H L
Sbjct: 246 YPEEISLTWQREGEDQ--TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGL 303
Query: 288 GGQDIILYWGHHFSMNWIALVVIVPLVILIV-----LVLWFKK 325
+ + L W +++ + +IV LV+L+V V+W KK
Sbjct: 304 -QEPLTLRW-EPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKK 344
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 72.8 bits (177), Expect = 4e-13
Identities = 53/190 (27%), Positives = 85/190 (44%), Gaps = 18/190 (9%)
Query: 114 VQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQYE 171
+Q + GCE+ + +S F++ ++G D + F WVP + + +
Sbjct: 117 LQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQ---------K 167
Query: 172 GVTETVY-----NLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCH 226
E VY + CP L L K + RQ P ++S + G + L C
Sbjct: 168 WEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLK-CL 226
Query: 227 ASGFYPKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSS 286
A FYP + V W R + Q GD+L N +GT+ V++ V ++ A SC V+HSS
Sbjct: 227 AYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSS 286
Query: 287 LGGQDIILYW 296
L Q +++ W
Sbjct: 287 L-AQPLVVPW 295
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 14/227 (6%)
Query: 104 SQDYSKYPFEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVC 163
+ ++SK +QV GCE+ S EG+++ ++G D L F T +
Sbjct: 85 NHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL 144
Query: 164 HLLNHQYEGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLL 223
H+ Y + CP L LL+ G+ + +QV P ++ + S L
Sbjct: 145 EWERHKIRARQNRAY--LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH--VTSSVTTL 200
Query: 224 VCHASGFYPKPVWVTWMRNEQ--EQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCR 281
C A +YP+ + + W++++Q + + D+LPN DGT+ + L V E +C+
Sbjct: 201 RCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQ 260
Query: 282 VRHSSLGGQDIILYWGHHFS-------MNWIALVVIVPLVILIVLVL 321
V H L Q +I+ W S ++ IA+ V++ + ++ ++L
Sbjct: 261 VEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 306
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 14/227 (6%)
Query: 104 SQDYSKYPFEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVC 163
+ ++SK +QV GCE+ S EG+++ ++G D L F T +
Sbjct: 108 NHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL 167
Query: 164 HLLNHQYEGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLL 223
H+ Y + CP L LL+ G+ + +QV P ++ + S L
Sbjct: 168 EWERHKIRARQNRAY--LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH--VTSSVTTL 223
Query: 224 VCHASGFYPKPVWVTWMRNEQ--EQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCR 281
C A +YP+ + + W++++Q + + D+LPN DGT+ + L V E +C+
Sbjct: 224 RCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQ 283
Query: 282 VRHSSLGGQDIILYWGHHFS-------MNWIALVVIVPLVILIVLVL 321
V H L Q +I+ W S ++ IA+ V++ + ++ ++L
Sbjct: 284 VEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 329
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 69.3 bits (168), Expect = 4e-12
Identities = 58/224 (25%), Positives = 97/224 (43%), Gaps = 19/224 (8%)
Query: 114 VQVKAGCELHS-GKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQY 170
+Q GC+L S G+ G+ Q A++G D L+ +W + +++ C N
Sbjct: 119 LQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN--- 175
Query: 171 EGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGF 230
V E + TC +L L+ GK + R P+ ++ P + L C A GF
Sbjct: 176 --VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDY-EATLRCWALGF 232
Query: 231 YPKPVWVTWMRNEQEQL-GTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGG 289
YP + +TW R+ ++Q + + P DGT+ + V S E +C V+H L
Sbjct: 233 YPAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-P 291
Query: 290 QDIILYWGHHFSMNWIALVVIVPLVIL--------IVLVLWFKK 325
+ ++L W + ++ LV+L + VLW KK
Sbjct: 292 EPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKK 335
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 67.8 bits (164), Expect = 1e-11
Identities = 56/219 (25%), Positives = 93/219 (42%), Gaps = 19/219 (8%)
Query: 119 GCELH-SGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQYEGVTE 175
GC++ G+ G+ Q A++G D +S +W + + Q ++ E E
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRF-----YEAEEYAE 175
Query: 176 TVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPV 235
+ C L L+ GK + R P+A ++ P + + L C A GFYP +
Sbjct: 176 EFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHP-ISDHEATLRCWALGFYPAEI 234
Query: 236 WVTWMRNEQEQL-GTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIIL 294
+TW R+ +EQ T+ + P DGT+ + V E +C V+H L Q +IL
Sbjct: 235 TLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGL-PQPLIL 293
Query: 295 YWGHHFSMNWIALVVIVPLVIL--------IVLVLWFKK 325
W + ++ LV+L + V+W KK
Sbjct: 294 RWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKK 332
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 67.8 bits (164), Expect = 1e-11
Identities = 56/219 (25%), Positives = 93/219 (42%), Gaps = 19/219 (8%)
Query: 119 GCELH-SGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQYEGVTE 175
GC++ G+ G+ Q A++G D +S +W + + Q ++ E E
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRF-----YEAEEYAE 175
Query: 176 TVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPV 235
+ C L L+ GK + R P+A ++ P + + L C A GFYP +
Sbjct: 176 EFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHP-ISDHEATLRCWALGFYPAEI 234
Query: 236 WVTWMRNEQEQL-GTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIIL 294
+TW R+ +EQ T+ + P DGT+ + V E +C V+H L Q +IL
Sbjct: 235 TLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGL-PQPLIL 293
Query: 295 YWGHHFSMNWIALVVIVPLVIL--------IVLVLWFKK 325
W + ++ LV+L + V+W KK
Sbjct: 294 RWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKK 332
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 67.4 bits (163), Expect = 2e-11
Identities = 54/217 (24%), Positives = 97/217 (44%), Gaps = 14/217 (6%)
Query: 114 VQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGV 173
+QV GCE+ S EG+++ ++G D L F T + H+
Sbjct: 30 LQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRAR 89
Query: 174 TETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPK 233
Y + CP L LL+ G+ + +QV P ++ + S L C A +YP+
Sbjct: 90 QNRAY--LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVT--SSVTTLRCRALNYYPQ 145
Query: 234 PVWVTWMRNEQEQLGTKHG--DILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQD 291
+ + W++++Q + D+LPN DGT+ + L V E +C+V H L Q
Sbjct: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQP 204
Query: 292 IILYWGHHFS-------MNWIALVVIVPLVILIVLVL 321
+I+ W S ++ IA+ V++ + ++ ++L
Sbjct: 205 LIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 241
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 65.5 bits (158), Expect = 6e-11
Identities = 77/291 (26%), Positives = 124/291 (42%), Gaps = 32/291 (10%)
Query: 8 LLALLLPGGDNADASQEHVS--FHVIQIFSFVNQS---WARGQGSGWLDELQTHGWDSES 62
LL LLPG A++ H+S +H+ + S + W SGWL Q ++S
Sbjct: 13 LLLFLLPGSLGAES---HLSLLYHLTAVSSPAPGTPAFWV----SGWLGPQQYLSYNSLR 65
Query: 63 GTIIFLHNWSKGN----FSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKA 118
G W N + +E +DL + + +L + K P+ +Q
Sbjct: 66 GEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFL--------EAFKALGGKGPYTLQGLL 117
Query: 119 GCELHSGKSPEGFFQVAFNGLDLLSF--QNTTWVPSPGCGSLAQSVCHLLNHQYEGVTET 176
GCEL + + A NG + ++F + TW G A ++ Q + +
Sbjct: 118 GCELGPDNTSVPTAKFALNGEEFMNFDLKQGTW---GGDWPEALAISQRWQQQDKAANKE 174
Query: 177 VYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVW 236
+ L+ S CP L L+ G+ + + P L +RPS G +L C A FYP +
Sbjct: 175 LTFLLFS-CPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQ 232
Query: 237 VTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSL 287
+ ++RN GT GD PN+DG+++ L V S + C V+H+ L
Sbjct: 233 LRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL 282
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 65.5 bits (158), Expect = 6e-11
Identities = 77/291 (26%), Positives = 124/291 (42%), Gaps = 32/291 (10%)
Query: 8 LLALLLPGGDNADASQEHVS--FHVIQIFSFVNQS---WARGQGSGWLDELQTHGWDSES 62
LL LLPG A++ H+S +H+ + S + W SGWL Q ++S
Sbjct: 13 LLLFLLPGSLGAES---HLSLLYHLTAVSSPAPGTPAFWV----SGWLGPQQYLSYNSLR 65
Query: 63 GTIIFLHNWSKGN----FSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKA 118
G W N + +E +DL + + +L + K P+ +Q
Sbjct: 66 GEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFL--------EAFKALGGKGPYTLQGLL 117
Query: 119 GCELHSGKSPEGFFQVAFNGLDLLSF--QNTTWVPSPGCGSLAQSVCHLLNHQYEGVTET 176
GCEL + + A NG + ++F + TW G A ++ Q + +
Sbjct: 118 GCELGPDNTSVPTAKFALNGEEFMNFDLKQGTW---GGDWPEALAISQRWQQQDKAANKE 174
Query: 177 VYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVW 236
+ L+ S CP L L+ G+ + + P L +RPS G +L C A FYP +
Sbjct: 175 LTFLLFS-CPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQ 232
Query: 237 VTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSL 287
+ ++RN GT GD PN+DG+++ L V S + C V+H+ L
Sbjct: 233 LRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL 282
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 64.7 bits (156), Expect = 1e-10
Identities = 54/227 (23%), Positives = 98/227 (43%), Gaps = 28/227 (12%)
Query: 104 SQDYSKYPFEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVC 163
+ ++SK +QV GCE+ S EG+++ ++G D L F T +
Sbjct: 108 NHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL 167
Query: 164 HLLNHQYEGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLL 223
H+ Y + CP L LL+ G+ + +QV L
Sbjct: 168 EWERHKIRARQNRAY--LERDCPAQLQQLLELGRGVLDQQV----------------TTL 209
Query: 224 VCHASGFYPKPVWVTWMRNEQ--EQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCR 281
C A +YP+ + + W++++Q + + D+LPN DGT+ + L V E +C+
Sbjct: 210 RCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQ 269
Query: 282 VRHSSLGGQDIILYWGHHFS-------MNWIALVVIVPLVILIVLVL 321
V H L Q +I+ W S ++ IA+ V++ + ++ ++L
Sbjct: 270 VEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 315
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 64.3 bits (155), Expect = 1e-10
Identities = 50/212 (23%), Positives = 92/212 (43%), Gaps = 11/212 (5%)
Query: 114 VQVKAGCELH-SGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQY 170
+Q +GC+L G+ G+ Q A++G D ++ +W + + Q
Sbjct: 119 LQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR--- 175
Query: 171 EGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGF 230
E + + TC +L L+ GK + R P+ ++ P L + L C A GF
Sbjct: 176 --AAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHP-LSDHEATLRCWALGF 232
Query: 231 YPKPVWVTWMRNEQEQL-GTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGG 289
YP + +TW R+ ++Q T+ + P DGT+ + V S + +C ++H L
Sbjct: 233 YPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGL-Q 291
Query: 290 QDIILYWGHHFSMNWIALVVIVPLVILIVLVL 321
+ + L W + ++ L +L+VL +
Sbjct: 292 EPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAV 323
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 63.9 bits (154), Expect = 2e-10
Identities = 55/226 (24%), Positives = 99/226 (43%), Gaps = 23/226 (10%)
Query: 114 VQVKAGCELHS-GKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQY 170
+Q+ GC++ S G+ G+ Q A++G D ++ +W + A + ++
Sbjct: 119 IQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSW-------TAADMAAQITKRKW 171
Query: 171 EGV--TETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHAS 228
E E + + TC +L L+ GK + R P+ ++ P + + L C A
Sbjct: 172 EAAHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHP-ISDHEATLRCWAL 230
Query: 229 GFYPKPVWVTWMRNEQEQL-GTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSL 287
GFYP + +TW R+ ++Q T+ + P DGT+ + V S E +C V+H L
Sbjct: 231 GFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL 290
Query: 288 GGQDIILYWGHHFSMNWIALVVIVPLVIL--------IVLVLWFKK 325
+ + L W + +I LV+L + V+W +K
Sbjct: 291 -PKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRK 335
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 61.6 bits (148), Expect = 9e-10
Identities = 52/217 (23%), Positives = 92/217 (42%), Gaps = 28/217 (12%)
Query: 114 VQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGV 173
+QV GCE+ S EG+++ ++G D L F T + H+
Sbjct: 30 LQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRAR 89
Query: 174 TETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPK 233
Y + CP L LL+ G+ + +QV L C A +YP+
Sbjct: 90 QNRAY--LERDCPAQLQQLLELGRGVLDQQVTT----------------LRCRALNYYPQ 131
Query: 234 PVWVTWMRNEQEQLGTKHG--DILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQD 291
+ + W++++Q + D+LPN DGT+ + L V E +C+V H L Q
Sbjct: 132 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL-DQP 190
Query: 292 IILYWGHHFS-------MNWIALVVIVPLVILIVLVL 321
+I+ W S ++ IA+ V++ + ++ ++L
Sbjct: 191 LIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIIL 227
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 58.5 bits (140), Expect = 8e-09
Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 21/224 (9%)
Query: 120 CELHSGKSPEGFFQVAFNGLDLLS--FQNTTWV--PSPGCGSLAQSVCHLLNHQYEGVTE 175
CE+H S ++G LS + W S +LA +V + L T+
Sbjct: 119 CEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMK-TK 177
Query: 176 TVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPV 235
T Y+ + + C + L L +G V R+ P +R G + + C ASGFYP +
Sbjct: 178 THYHAMHADCLQELRRYLKSG--VVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNI 235
Query: 236 WVTWMRNEQEQLGTKH-----GDILPNADGTWYLQVILEVASEEPAGLSCRVRHSS---- 286
++W Q+ + H GD+LP+ +GT+ V + E +C + HS
Sbjct: 236 TLSW---RQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHST 292
Query: 287 --LGGQDIILYWGHHFSMNWIALVVIVPLVILIVLVLWFKKHCS 328
+ +++ H + + A+ VI+I V KK S
Sbjct: 293 HPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTS 336
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 58.2 bits (139), Expect = 1e-08
Identities = 47/178 (26%), Positives = 80/178 (44%), Gaps = 13/178 (7%)
Query: 120 CELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVC-HLLNHQYEGV--TET 176
CE+H S G ++G LS T + S AQ++ ++ N E T+T
Sbjct: 119 CEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKT 178
Query: 177 VYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVW 236
Y +++ C + L L +G + + R V P ++ + G + + C AS FYP+ +
Sbjct: 179 HYRAMQADCLQKLQRYLKSG-VAIRRTVPPMVNVTCS-EVSEGNITVTCRASSFYPRNIT 236
Query: 237 VTWMRNEQEQLGTKH-----GDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGG 289
+TW Q+ + H GD+LP+ +GT+ V + E +C + HS G
Sbjct: 237 LTW---RQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHG 291
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 58.2 bits (139), Expect = 1e-08
Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 19/219 (8%)
Query: 119 GCELH-SGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQYEGVTE 175
GCEL G+ G+ Q A++G D L+ +W +++ N E +
Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKS---NDASEAEHQ 177
Query: 176 TVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPV 235
Y + TC +L L+ GK + P+ ++ P + + L C A GFYP +
Sbjct: 178 RAY--LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHP-ISDHEATLRCWALGFYPAEI 234
Query: 236 WVTWMRN-EQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIIL 294
+TW ++ E T+ + P DGT+ + V S E +C V+H L + + L
Sbjct: 235 TLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL-PEPVTL 293
Query: 295 YWGHHFSMNWIALVVIVPLVIL--------IVLVLWFKK 325
W + +I LV+L + V+W KK
Sbjct: 294 RWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKK 332
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 55.8 bits (133), Expect = 5e-08
Identities = 49/214 (22%), Positives = 91/214 (42%), Gaps = 15/214 (7%)
Query: 114 VQVKAGCELH-SGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQY 170
+Q GC++ G+ G Q A++G D ++ +W + A + + ++
Sbjct: 119 LQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSW-------TAADTAAQITQRKW 171
Query: 171 EGVTETVYN--LIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHAS 228
E E + C +L L+ GK + R P+ ++ P + + L C A
Sbjct: 172 EAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHP-ISDHEATLRCWAL 230
Query: 229 GFYPKPVWVTWMRNEQEQL-GTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSL 287
GFYP + +TW R+ ++Q T+ + P D T+ + V S E +C V+H L
Sbjct: 231 GFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGL 290
Query: 288 GGQDIILYWGHHFSMNWIALVVIVPLVILIVLVL 321
+ + L W + ++ L +L V+V+
Sbjct: 291 -PKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVI 323
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 55.5 bits (132), Expect = 7e-08
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 196 GKMYVHRQVRPEAWLS-SRPSLGSGQLLLVCHASGFYPKPVWVTWMRNEQEQ-LGTKHGD 253
G M + R+V+P +S S+ LLVCH + FYP + V W N QE+ G +
Sbjct: 114 GPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTN 173
Query: 254 ILPNADGTWYLQVILEVASEEPAGLSCRVRHSSL 287
++ N D T+ + V+LE+ ++ +C+V H+SL
Sbjct: 174 LIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSL 207
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,198,020
Number of Sequences: 37866
Number of extensions: 668537
Number of successful extensions: 1553
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 1378
Number of HSP's gapped (non-prelim): 129
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.