Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 163965434
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163965434 dapper, antagonist of beta-catenin, homolog 2
[Homo sapiens]
(774 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo... 1576 0.0
gi|24158478 dapper 1 isoform 1 [Homo sapiens] 179 1e-44
gi|118498364 dapper 1 isoform 2 [Homo sapiens] 105 1e-22
gi|182507165 thymus expressed gene 3-like [Homo sapiens] 84 6e-16
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 52 2e-06
gi|144953905 hypothetical protein LOC55138 [Homo sapiens] 52 2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 49 2e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 47 9e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens] 46 2e-04
gi|150170670 piccolo isoform 2 [Homo sapiens] 46 2e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 46 2e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 45 2e-04
gi|19924097 synapsin I isoform Ib [Homo sapiens] 44 6e-04
gi|19924099 synapsin I isoform Ia [Homo sapiens] 42 0.002
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 41 0.004
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 41 0.005
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 41 0.005
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 41 0.005
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 41 0.005
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 41 0.005
gi|188536004 zinc finger protein 469 [Homo sapiens] 41 0.005
gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens] 41 0.005
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 41 0.005
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 40 0.006
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 40 0.006
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 40 0.006
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 40 0.006
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 40 0.008
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 40 0.008
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 40 0.008
>gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo
sapiens]
Length = 774
Score = 1576 bits (4080), Expect = 0.0
Identities = 774/774 (100%), Positives = 774/774 (100%)
Query: 1 MWTPGGPPGSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCG 60
MWTPGGPPGSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCG
Sbjct: 1 MWTPGGPPGSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCG 60
Query: 61 PHGLHGPEQQLEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDS 120
PHGLHGPEQQLEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDS
Sbjct: 61 PHGLHGPEQQLEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDS 120
Query: 121 DSRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD 180
DSRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD
Sbjct: 121 DSRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD 180
Query: 181 ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAE 240
ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAE
Sbjct: 181 ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAE 240
Query: 241 LLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGG 300
LLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGG
Sbjct: 241 LLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGG 300
Query: 301 PSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHA 360
PSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHA
Sbjct: 301 PSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHA 360
Query: 361 ASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSL 420
ASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSL
Sbjct: 361 ASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSL 420
Query: 421 PEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH 480
PEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH
Sbjct: 421 PEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH 480
Query: 481 PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWP 540
PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWP
Sbjct: 481 PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWP 540
Query: 541 TGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALFPFEASLLTS 600
TGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALFPFEASLLTS
Sbjct: 541 TGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALFPFEASLLTS 600
Query: 601 VARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSD 660
VARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSD
Sbjct: 601 VARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSD 660
Query: 661 SEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYV 720
SEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYV
Sbjct: 661 SEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYV 720
Query: 721 AAGHAELAWTQEAPVSSGPLLSPVPKLCRIKASKALKKKIRRFQPTALKVMTMV 774
AAGHAELAWTQEAPVSSGPLLSPVPKLCRIKASKALKKKIRRFQPTALKVMTMV
Sbjct: 721 AAGHAELAWTQEAPVSSGPLLSPVPKLCRIKASKALKKKIRRFQPTALKVMTMV 774
>gi|24158478 dapper 1 isoform 1 [Homo sapiens]
Length = 836
Score = 179 bits (453), Expect = 1e-44
Identities = 241/872 (27%), Positives = 348/872 (39%), Gaps = 176/872 (20%)
Query: 9 GSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPE 68
G A +R+R R A AGL EL+ LR Q+ VRGAL AAP L
Sbjct: 35 GEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAA 94
Query: 69 QQ-------LEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSD 121
Q+ LE + L++QL+ LR++D GL L +LD QIS L+LDV S E L++D
Sbjct: 95 QRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETD 154
Query: 122 SRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDE 181
SRPSSGFYE+SDG S SLS S SV S+ +S S S +A S+ D P+S D
Sbjct: 155 SRPSSGFYELSDGASGSLSNSSNSVFSECLS-SCHSSTCFCSPLEATLSLSDGCPKSADL 213
Query: 182 TTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAEL 241
+ ++ E+ A G+V R +ST +
Sbjct: 214 IGLLEYKEGHCEDQA--SGAV-----------CRSLSTPQFN------------------ 242
Query: 242 LGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGP 301
+D+ V +PKY+ DLVS+ G +VY YPSPLHAVA+QSP+F+L G P
Sbjct: 243 ------SLDVIADV-NPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLC----LTGNP 291
Query: 302 SFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGE-------Q 354
RE R + I G L+A + + + LW P+ + + Q
Sbjct: 292 L--REEDRLGNHASDICGGSELDA--VKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQ 347
Query: 355 GPLRHAASPSPQRQGGWSTDGG----GRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMP 410
+ P+ G G + V APG +G + + + G
Sbjct: 348 KKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPS 407
Query: 411 LEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKS 470
L + S P++ SK S + SK P G + + S+ L K+
Sbjct: 408 LN--NGTFSPPKQWSKESKA---------EQAESKRVPLPEGCPSGAASDLQ-SKHLPKT 455
Query: 471 PSPASGHFAH---------PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRP 521
PAS A P +A L PK E R P QPL + +
Sbjct: 456 AKPASQEHARCSAIGTGESPKESAQLSGASPK---ESPSRGPAPPQENKVVQPLKKMSQK 512
Query: 522 EGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-ESTLYPMPVLVP------ 574
P + +P ++ RPAL +++ G S S E +P
Sbjct: 513 NSLQGVPPATPPLLSTAFP-----VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 567
Query: 575 --------LAVAPQESHRTSAQALFPFEASLLT----SVARRKHRRWQSTVEISARARLA 622
+ V S + AL E L T + A K R+ ++ + + + A
Sbjct: 568 RLHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKA 627
Query: 623 SC--------PESNL-GPPRPVARRAGGPL-ARGRPSLVRQDAYTRSD------------ 660
S PE+ + G P RAG GR ++V + + R+D
Sbjct: 628 SSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISY 687
Query: 661 ---------------------------------SEPSKHSAECDPRFPSVIPETSEGESS 687
+ S++SAEC+ F S + +TSE E S
Sbjct: 688 EEALRRARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQS 747
Query: 688 DHTTNRFGDRESSSSDEEGGAQS---RDCDLALGYVAAGHAELAWTQEAPVSSGPLL--S 742
++TTN FGD ESS S+ E +S D + + G + ++ T + P L
Sbjct: 748 NYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLI---WSQFVQTLPIQTVTAPDLHNH 804
Query: 743 PVPKLCRIKASKALKKKIRRFQPTALKVMTMV 774
P +IKAS LKKKI RF+ +LK+MT V
Sbjct: 805 PAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836
>gi|118498364 dapper 1 isoform 2 [Homo sapiens]
Length = 799
Score = 105 bits (263), Expect = 1e-22
Identities = 77/179 (43%), Positives = 98/179 (54%), Gaps = 8/179 (4%)
Query: 9 GSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPE 68
G A +R+R R A AGL EL+ LR Q+ VRGAL AAP L
Sbjct: 35 GEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAA 94
Query: 69 QQ-------LEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSD 121
Q+ LE + L++QL+ LR++D GL L +LD QIS L+LDV S E L++D
Sbjct: 95 QRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETD 154
Query: 122 SRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD 180
SRPSSGFYE+SDG S SLS S SV S+ +S S S +A S+ D P+S D
Sbjct: 155 SRPSSGFYELSDGASGSLSNSSNSVFSECLS-SCHSSTCFCSPLEATLSLSDGCPKSAD 212
Score = 99.0 bits (245), Expect = 1e-20
Identities = 155/617 (25%), Positives = 232/617 (37%), Gaps = 130/617 (21%)
Query: 257 DPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNT 316
+PKY+ DLVS+ G +VY YPSPLHAVA+QSP+F+L G P RE R +
Sbjct: 214 NPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLC----LTGNPL--REEDRLGNHASD 267
Query: 317 IQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGE-------QGPLRHAASPSPQRQG 369
I G L+A + + + LW P+ + + Q + P+
Sbjct: 268 ICGGSELDA--VKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSV 325
Query: 370 GWSTDGG----GRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGS 425
G G + V APG +G + + + G L + S P++ S
Sbjct: 326 NADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLN--NGTFSPPKQWS 383
Query: 426 KPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH----- 480
K S + SK P G + + S+ L K+ PAS A
Sbjct: 384 KESKA---------EQAESKRVPLPEGCPSGAASDLQ-SKHLPKTAKPASQEHARCSAIG 433
Query: 481 ----PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDP 536
P +A L PK E R P QPL + + P +
Sbjct: 434 TGESPKESAQLSGASPK---ESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLS 490
Query: 537 AHWPTGRGGLQRRPALAWEAPGRSCS-ESTLYPMPVLVP--------------LAVAPQE 581
+P ++ RPAL +++ G S S E +P + V
Sbjct: 491 TAFP-----VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNS 545
Query: 582 SHRTSAQALFPFEASLLT----SVARRKHRRWQSTVEISARARLASC--------PESNL 629
S + AL E L T + A K R+ ++ + + + AS PE+ +
Sbjct: 546 SLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGV 605
Query: 630 -GPPRPVARRAGGPL-ARGRPSLVRQDAYTRSD--------------------------- 660
G P RAG GR ++V + + R+D
Sbjct: 606 PGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENV 665
Query: 661 ------------------SEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSS 702
+ S++SAEC+ F S + +TSE E S++TTN FGD ESS S
Sbjct: 666 GLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVS 725
Query: 703 DEEGGAQS---RDCDLALGYVAAGHAELAWTQEAPVSSGPLL--SPVPKLCRIKASKALK 757
+ E +S D + + G + ++ T + P L P +IKAS LK
Sbjct: 726 EGEFVGESTTTSDSEESGGLI---WSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLK 782
Query: 758 KKIRRFQPTALKVMTMV 774
KKI RF+ +LK+MT V
Sbjct: 783 KKILRFRSGSLKLMTTV 799
>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
Length = 629
Score = 83.6 bits (205), Expect = 6e-16
Identities = 205/794 (25%), Positives = 270/794 (34%), Gaps = 209/794 (26%)
Query: 14 DRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPEQQLEA 73
+R RL L + AGL EL LR Q+ RV+ AL L P A ++ A
Sbjct: 12 ERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAA 71
Query: 74 A---LAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSDSRPSSGFYE 130
A AAL+EQL L GL L Q Q+ L L+ G L+ +S SSGFYE
Sbjct: 72 ARRAAAALEEQLEALP----GLVWDLGQ---QLGDLSLESG-----GLEQESGRSSGFYE 119
Query: 131 --MSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDETTVPAWR 188
S GG S ++ S S G L P + R RP+S+ + +
Sbjct: 120 DPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGP----SEPRGIYASERPKSLGDAS----- 170
Query: 189 PQATEE-GARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQ 247
P A E GAR A P P P + G +A + AE
Sbjct: 171 PSAPEVVGAR-------AAVPRSFSAPYPTAGGSAG---------PEACSSAE------- 207
Query: 248 GVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKET--PQRGGPSFPR 305
+ + PSPLHAVA++SP T P GG P
Sbjct: 208 ------------------RRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPL 249
Query: 306 ES-------PRGPAGLNTIQTGPV-LEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357
+ R G +T P + GP R + R+ P S G
Sbjct: 250 DGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSV---------RQRPPDASPSP-GSA 299
Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQS 417
R A PS +R GG T +A E E P P
Sbjct: 300 RPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE--------------------PAAP 339
Query: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477
+ P P+ ++ KAQ P AQ RG P R + P
Sbjct: 340 PAAPSPPDSPAEGRLV-----------KAQYIPGAQAATRG---LPGRAARRKP------ 379
Query: 478 FAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPA 537
PP ++ +++SP + R A + R A A+ +
Sbjct: 380 -------------PPLTRGRSVEQSPPRERPRAAGR------RGRMAEASGR-------- 412
Query: 538 HWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLA-----VAPQESHRTSAQALFP 592
RG + R A RS SE++L VP A +E R P
Sbjct: 413 -----RGSPRARKA------SRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGP 461
Query: 593 FEASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVR 652
A L + A RRW+ST EI A + P P AR G + P
Sbjct: 462 --APTLAAQAAGSCRRWRSTAEIDA------ADGRRVRPRAPAARVPGPGPSPSAPQRRL 513
Query: 653 QDAYTRSDSEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGA---Q 709
SDSE S P G + +G+ ESS+S+ E A
Sbjct: 514 LYGCAGSDSECSAGRLG---------PLGRRGPAGG-VGGGYGESESSASEGESPAFSSA 563
Query: 710 SRDCDLALGYVAAGHAELAWTQEAPVSS---------GPLLSPVPKLCRIKASKALKKKI 760
S D D G L W Q+ ++ G P +IKAS ALKKKI
Sbjct: 564 SSDSD--------GSGGLVWPQQLVAATAASGGGAGAGAPAGPAKVFVKIKASHALKKKI 615
Query: 761 RRFQPTALKVMTMV 774
RF+ +LKVMT V
Sbjct: 616 LRFRSGSLKVMTTV 629
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 52.0 bits (123), Expect = 2e-06
Identities = 90/337 (26%), Positives = 119/337 (35%), Gaps = 75/337 (22%)
Query: 294 ETPQRGGPSFPRESP------RGPAGLNTIQTGPVLEAGPARARAYIDRL----LHLWGR 343
E+ R GP+ P R P NT GPV G A L L +
Sbjct: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNT-SPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 344 ETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAG---- 399
ET A+G E P R A S +R T PG +SR AG
Sbjct: 131 ETVARGKATE-APKRSALSAGARRDTSGPT----------PGTPSPAMARRSRAAGTEVG 179
Query: 400 --RGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGR 457
R P + P EGP++S S E S PS A++ PSA G
Sbjct: 180 LPRPAPSARPRPPTEGPRKSVSSASEHS-------------TTEPSPAARRRPSA---GG 223
Query: 458 GNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLL 517
G SR L S +P S P+ + G P++ A P K L+ R P +
Sbjct: 224 GLQRPASRSLSSSATPLSS----PARSGPSARGTPRAPAH--PSQPKPKGLQALRPPQVT 277
Query: 518 LDRPEGAH----------AAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSE---- 563
R + A A P PS P+ P+ LQ P+ P ++ +
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS----LQTLPSPPATPPSQATTSLGSP 333
Query: 564 -----STLYPMPVLVPLAVAPQESHRTSAQALFPFEA 595
+ P P L PLA P ++ A AL P +A
Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQA--PPALALPPLQA 368
Score = 33.5 bits (75), Expect = 0.77
Identities = 90/384 (23%), Positives = 119/384 (30%), Gaps = 57/384 (14%)
Query: 123 RPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDET 182
RPS+G + S SLS+S + S S P A AH ++P +P+ +
Sbjct: 218 RPSAGG-GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-----KPKGLQAL 271
Query: 183 TVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELL 242
P P +DA G P++T P+ + SA L
Sbjct: 272 RPPQVTPPR-----------KDAAPALGPLSSSPLAT-------PSPSAPPSPSAPPSL- 312
Query: 243 GLLCQGVDIPLHVPDPKYRQDLVS---QGGREVYPYPSPLHAVALQSPLFVLTKETPQRG 299
Q + P P + L S Q P P PL +A P P
Sbjct: 313 ----QTLPSPPATPPSQATTSLGSPTLQATHSFLPSP-PLSPLATPPPQAPPALALPPLQ 367
Query: 300 GPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRH 359
P P SP P+ P A LL P S Q P
Sbjct: 368 APPSPPASP---------PLSPLATPSPQAPNALAVHLLQAPFSPPP---SPPVQAPFSP 415
Query: 360 AASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGS 419
ASP P L P + PA + P Q PL P +
Sbjct: 416 PASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474
Query: 420 LPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFA 479
P + P+ A+P +A +P A G+ SPS L SP A
Sbjct: 475 KPPPQAPPA----------LATPPLQALPSPPASFPGQAPF-SPSASLPMSPLATPPPQA 523
Query: 480 HPSFAASLKMGPPKSKAEKIKRSP 503
P AA L PP A ++P
Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAP 547
>gi|144953905 hypothetical protein LOC55138 [Homo sapiens]
Length = 464
Score = 52.0 bits (123), Expect = 2e-06
Identities = 88/371 (23%), Positives = 132/371 (35%), Gaps = 61/371 (16%)
Query: 337 LLHLWGRETPAKGSEGEQGP------LRHAASPSP---------------QRQGGWSTDG 375
LLH++ R+ P K ++G LR A+ P P R +D
Sbjct: 117 LLHIFSRKPPEKPLPNQKGSTESSDYLRVASGPMPVHTTSKRPRVDPVLSDRSATEMSDR 176
Query: 376 GGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRE 435
G L +P R+ + S G +P + G P KP++S
Sbjct: 177 GSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQTAVRHQGPEPLLVVKPTHS----- 231
Query: 436 TMVQASPSSKAQQTPSA--QDYGRGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPK 493
SP+ ++ P A + +G +SP DK P+ S P+ SL +G
Sbjct: 232 -----SPAGGCREVPQAASKTHGLLQAVSPQAQ-DKRPAVTSQP-CPPAATHSLGLGSNL 284
Query: 494 SKAEKIKRS---PMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRP 550
S KRS P+ L F ++P L G P+ +++ P LQ P
Sbjct: 285 SFGPGAKRSAPAPIQACLNFPKKPRL------GPFQIPESAIQGGELGAPEN---LQPPP 335
Query: 551 ALAWEAPGRSCSESTLYPMPVL------------VPLAVAPQESHRTSAQALFPFEASLL 598
A P S T P VL +P A A SH +A L
Sbjct: 336 AATELGPRTSPQTGTRTPAQVLSGDRQPPHSRPCLPTAQACTMSHHPAAS--HDGAQPLR 393
Query: 599 TSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTR 658
R ++ RW S++ + P + L V+ ++ GP R PS++ +D
Sbjct: 394 VLFRRLENGRWSSSLLTAPSFHSPEKPGAFLAQSPHVSEKSEGPCVRVPPSVLYEDLQVP 453
Query: 659 SDSEPSKHSAE 669
S SE S E
Sbjct: 454 SSSEDSDSDLE 464
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 48.5 bits (114), Expect = 2e-05
Identities = 81/303 (26%), Positives = 108/303 (35%), Gaps = 57/303 (18%)
Query: 295 TPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQ 354
T R S P S RG T P + P RA T G G++
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG------------TTRPGPLGQK 132
Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPA----------QSRGAG----- 399
G LR +A + R G +T+ R + A R D GP +SR AG
Sbjct: 133 G-LRISAEETVAR--GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 400 -RGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRG 458
R P + P EGP++S S E S PS A++ PSA G G
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHS-------------TTEPSPAARRRPSA---GGG 233
Query: 459 NIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLL 518
SR L S +P S P+ + G P++ A P K L+ R P +
Sbjct: 234 LQRPASRSLSSSATPLSS----PARSGPSARGTPRAPAH--PSQPKPKGLQALRPPQVTP 287
Query: 519 DRPEGAHAAPQPSLEWDPAHWPTGRGGLQRR--PALAWEAPGRSCSESTLYPMPVLVPLA 576
R + A A L P P+ LQ + P L S + P+P+ P
Sbjct: 288 PRKDAAPAL--GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 577 VAP 579
AP
Sbjct: 346 SAP 348
Score = 35.4 bits (80), Expect = 0.20
Identities = 96/391 (24%), Positives = 122/391 (31%), Gaps = 41/391 (10%)
Query: 123 RPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPS---MGDWRPRSV 179
RPS+G + S SLS+S + S S P A AH ++P + RP V
Sbjct: 227 RPSAGG-GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 180 D---ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTG-DLDRALPADTGLQKA 235
+ PA P ++ A P S Q T P S+ A P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 236 SADAELLGLLCQGVDIPLHVPDPKYRQDLVS---QGGREVYPYPSPLHAVALQSPLFVLT 292
SA L Q + P P + L S Q P P PL +A P
Sbjct: 346 SAPPSL-----QTLPSPPATPPSQATTSLGSPTLQATHSFLPSP-PLSPLATPPPQAPPA 399
Query: 293 KETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEG 352
P P P SP P+ P A LL P S
Sbjct: 400 LALPPLQAPPSPPASP---------PLSPLATPSPQAPNALAVHLLQAPFSPPP---SPP 447
Query: 353 EQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLE 412
Q P ASP P L P + PA + P Q PL
Sbjct: 448 VQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 413 GPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPS 472
P + P + P+ A+P +A +P A G+ SPS L SP
Sbjct: 507 APPLQLAKPPPQAPPA----------LATPPLQALPSPPASFPGQAPF-SPSASLPMSPL 555
Query: 473 PASGHFAHPSFAASLKMGPPKSKAEKIKRSP 503
A P AA L PP A ++P
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 46.6 bits (109), Expect = 9e-05
Identities = 84/304 (27%), Positives = 112/304 (36%), Gaps = 62/304 (20%)
Query: 295 TPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQ 354
T R S P S RG T P + P RA T G G++
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG------------TTRPGPLGQK 132
Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPA----------QSRGAG----- 399
G LR +A + R G +T+ R + A R D GP +SR AG
Sbjct: 133 G-LRISAEETVAR--GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 400 -RGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRG 458
R P + P EGP++S S E S PS A++ PSA G G
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHS-------------TTEPSPAARRRPSA---GGG 233
Query: 459 NIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLL 518
SR L S +P S P+ + G P++ A P K L+ R P +
Sbjct: 234 LQRPASRSLSSSATPLSS----PARSGPSARGTPRAPAH--PSQPKPKGLQALRPPQVTP 287
Query: 519 DRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS--ESTLYPMPVL-VPL 575
R + A A L P P+ G + RP P + + +TL P P L PL
Sbjct: 288 PRKDAAPAL--GPLSSSPLATPS-PSGTKARPV---PPPDNAATPLPATLPPSPPLATPL 341
Query: 576 AVAP 579
+AP
Sbjct: 342 PLAP 345
Score = 31.6 bits (70), Expect = 2.9
Identities = 95/382 (24%), Positives = 126/382 (32%), Gaps = 55/382 (14%)
Query: 271 EVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNT--IQTGPVLEAGP- 327
E P P+P A SPL ETP S P+ P L + +Q P P
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPS----SIATPPPQAPPALASPPLQGLPSPPLSPL 614
Query: 328 ARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGRE 387
A L L + P S PL A+PSPQ + L+ AP
Sbjct: 615 ATPPPQAPPXLALPPLQAPP--SPPASPPLSPLATPSPQAPNALAVH-----LLQAPFSP 667
Query: 388 DEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQ 447
P Q+ + P P + P + P S V SP +
Sbjct: 668 PPSPPVQAPFSPPASP----------PVSPSATPPSQAPP--SLAAPPLQVPPSPPASPP 715
Query: 448 QTPSAQDYGRGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKV 507
+PSA + + L PSP + PS ++ PP A ++ P
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV-PPLLAAPPLQVPPSPP- 773
Query: 508 LRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRS-CSESTL 566
A P+ L +P AP P+L P LQ P+ PG++ S S
Sbjct: 774 ---ASLPMSPLAKP--PPQAP-PALATPP---------LQALPSPPASFPGQAPFSPSAS 818
Query: 567 YPMPVLVPLAVAPQESHRTSAQALFPF----EASLLTSVARRKHRRWQSTVEISARARLA 622
PM PLA P ++ A L AS RR T R LA
Sbjct: 819 LPMS---PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 875
Query: 623 SCPESNLGPPRPVARRAGGPLA 644
P GPP P +R L+
Sbjct: 876 LAP----GPPPPPSRSPSSTLS 893
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 45.8 bits (107), Expect = 2e-04
Identities = 76/339 (22%), Positives = 122/339 (35%), Gaps = 49/339 (14%)
Query: 264 LVSQGGREVYPYPSPLH-AVALQSPLFVLTKETPQRGGPSFPRE-SPRGPAGLN------ 315
LV+ G + P P P +Q+P FV P PS P +P PA
Sbjct: 217 LVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA 276
Query: 316 --TIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQRQGGWST 373
T+ P AGP A + PA G G A +P+P G
Sbjct: 277 PATLARPPGHPAGPPTAAPAVP---------PPAAAQNG--GSAGAAPAPAPAAGGPAGV 325
Query: 374 DG----GGRLLVFAPG-------REDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPE 422
G G APG R + P ++ GP + GP G+LP
Sbjct: 326 SGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPS 385
Query: 423 EGSKPSNSCVLRETMVQASPSSKAQ---QTPSAQDYGRGNIISPSRMLDKSPSPASGHFA 479
+ P + + + + + Q +TP+A G ++P+ + + P P
Sbjct: 386 PAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQ---- 441
Query: 480 HPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHW 539
+P+ + ++ P + RS ++L +Q L + AHA PQ ++ PA
Sbjct: 442 NPTNIQNFQLPP----GMVLVRSENGQLLMIPQQALAQMQAQ--AHAQPQTTMAPRPA-T 494
Query: 540 PTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVA 578
PT +Q +APG + P ++ ++ A
Sbjct: 495 PTSAPPVQISTV---QAPGTPIIARQVTPTTIIKQVSQA 530
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 45.8 bits (107), Expect = 2e-04
Identities = 75/297 (25%), Positives = 102/297 (34%), Gaps = 53/297 (17%)
Query: 185 PAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGL 244
PA T+ A+ PG+V+ QP GT P G + TG +K S++
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA-KPPAQQTGSEKPSSEQPGPKA 390
Query: 245 LCQGVDI---PLHVPDPKYRQDLVSQGGREVYPYPSPL-HAVALQSPLFVL--TKETPQR 298
L Q + P P P + Q G P PL LQSP TK Q+
Sbjct: 391 LAQPPGVGKTPAQQPGPA--KPPTQQVGT-----PKPLAQQPGLQSPAKAPGPTKTPVQQ 443
Query: 299 GGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLR 358
GP GP + QTGP PAK + GP
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG---------------PAKPPPQQPGP-- 486
Query: 359 HAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSG 418
A P PQ+ G P+Q G+ + PQQ G PQQ G
Sbjct: 487 --AKPPPQQPGSAKP------------------PSQQPGSTKPPPQQPGPAK-PSPQQPG 525
Query: 419 SLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPAS 475
S +P ++ + A PS++ P +Q G G + P + + P S
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT-GSGKPLQPPTVSPSAKQPPS 581
Score = 30.0 bits (66), Expect = 8.5
Identities = 71/321 (22%), Positives = 109/321 (33%), Gaps = 62/321 (19%)
Query: 153 PSLGSLLPVAQAHKARPSMGDWRPRSVDETT------VPAWRPQATEEGARPPGSVEDAG 206
PS PVA +P M V ++ +P+ + Q+ E P D+
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800
Query: 207 QPWGTFWPRPVSTGDLD-RALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLV 265
+P +F P D +A+P + ++D++++ P P
Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIP------RPASDSKIISH-----------PGPSSE---- 839
Query: 266 SQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTI-QTGPVLE 324
S+G ++V P + P TK +P+ P+ SP P T QT P +
Sbjct: 840 SKGQKQVDPVQKK------EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQ 893
Query: 325 AGPARARAYIDRLLHLWG-----RETPAKGSEGEQGPL-RHAASPSPQRQGGWSTDGGGR 378
P L+L + P E G L AS Q ST G
Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG--- 950
Query: 379 LLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKP----SNSCVLR 434
PG + GP G P +Q P + P G G P + V +
Sbjct: 951 ----QPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKK 998
Query: 435 ETMVQASP--SSKAQQTPSAQ 453
ET A+ KA+Q P+ +
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVK 1019
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 45.8 bits (107), Expect = 2e-04
Identities = 75/297 (25%), Positives = 102/297 (34%), Gaps = 53/297 (17%)
Query: 185 PAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGL 244
PA T+ A+ PG+V+ QP GT P G + TG +K S++
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA-KPPAQQTGSEKPSSEQPGPKA 390
Query: 245 LCQGVDI---PLHVPDPKYRQDLVSQGGREVYPYPSPL-HAVALQSPLFVL--TKETPQR 298
L Q + P P P + Q G P PL LQSP TK Q+
Sbjct: 391 LAQPPGVGKTPAQQPGPA--KPPTQQVGT-----PKPLAQQPGLQSPAKAPGPTKTPVQQ 443
Query: 299 GGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLR 358
GP GP + QTGP PAK + GP
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG---------------PAKPPPQQPGP-- 486
Query: 359 HAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSG 418
A P PQ+ G P+Q G+ + PQQ G PQQ G
Sbjct: 487 --AKPPPQQPGSAKP------------------PSQQPGSTKPPPQQPGPAK-PSPQQPG 525
Query: 419 SLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPAS 475
S +P ++ + A PS++ P +Q G G + P + + P S
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT-GSGKPLQPPTVSPSAKQPPS 581
Score = 30.0 bits (66), Expect = 8.5
Identities = 71/321 (22%), Positives = 109/321 (33%), Gaps = 62/321 (19%)
Query: 153 PSLGSLLPVAQAHKARPSMGDWRPRSVDETT------VPAWRPQATEEGARPPGSVEDAG 206
PS PVA +P M V ++ +P+ + Q+ E P D+
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800
Query: 207 QPWGTFWPRPVSTGDLD-RALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLV 265
+P +F P D +A+P + ++D++++ P P
Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIP------RPASDSKIISH-----------PGPSSE---- 839
Query: 266 SQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTI-QTGPVLE 324
S+G ++V P + P TK +P+ P+ SP P T QT P +
Sbjct: 840 SKGQKQVDPVQKK------EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQ 893
Query: 325 AGPARARAYIDRLLHLWG-----RETPAKGSEGEQGPL-RHAASPSPQRQGGWSTDGGGR 378
P L+L + P E G L AS Q ST G
Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG--- 950
Query: 379 LLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKP----SNSCVLR 434
PG + GP G P +Q P + P G G P + V +
Sbjct: 951 ----QPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKK 998
Query: 435 ETMVQASP--SSKAQQTPSAQ 453
ET A+ KA+Q P+ +
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVK 1019
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 45.4 bits (106), Expect = 2e-04
Identities = 77/339 (22%), Positives = 118/339 (34%), Gaps = 32/339 (9%)
Query: 412 EGPQQSGSLPEEGSKPSNSCVLRETM---VQASPSSKAQQTPSAQDYGRGNIISPSRMLD 468
E + + EG S + E + +Q S SS +PS+ SP +
Sbjct: 996 EDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPR-----TSPCQSPT 1050
Query: 469 KSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAP 528
S P PS A S GPP +++ I P + + L RP
Sbjct: 1051 ISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVA 1110
Query: 529 QPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQ 588
P+ P P G Q P PG + + +P + APQ R SA
Sbjct: 1111 PPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAG 1170
Query: 589 ALFPFEASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRP 648
L P S + + + + + + + A P+S+L PP + P+A P
Sbjct: 1171 RLTPESQSKTSETS-----KGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMP 1225
Query: 649 -SLVRQDAYTRSDSEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGG 707
S + + T P S+ P S P+ SD G RES +
Sbjct: 1226 QSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISD------GKRESPLKIDPFE 1279
Query: 708 AQSRDCDLALGYVAAGHAELAWTQEAPVSSGPLLSPVPK 746
DL+ +A A+L+ V + P+ +P PK
Sbjct: 1280 ------DLSFNLLAVSKAQLS------VQTSPVPTPDPK 1306
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 43.9 bits (102), Expect = 6e-04
Identities = 60/216 (27%), Positives = 78/216 (36%), Gaps = 39/216 (18%)
Query: 296 PQRGGPSFP-RESPRG---------PAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRET 345
PQR GP R P+G PAG Q P + P + + GR++
Sbjct: 474 PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533
Query: 346 -PAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQ 404
P G G R ASPSPQRQ G + V P P ++ GA GG Q
Sbjct: 534 RPVAGGPGAPPAARPPASPSPQRQAG-PPQATRQTSVSGP------APPKASGAPPGGQQ 586
Query: 405 QQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPS 464
+QG P + P +G P+ + + P + Q PS G G P
Sbjct: 587 RQG-PPQKPPGPAG--------PTRQASQAGPVPRTGPPTTQQPRPS----GPGPAGRPK 633
Query: 465 RMLDKSPS--------PASGHFAHPSFAASLKMGPP 492
L + PS A+G HP AS P
Sbjct: 634 PQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
Score = 37.4 bits (85), Expect = 0.053
Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 40/230 (17%)
Query: 356 PLRHAASPSPQRQGGWSTDGGGRL-LVFAPGREDEGGPAQSRGAGRGGPQQQGYMP-LEG 413
P + SP R T G L L ++ G PAQ R +GGP Q G P +G
Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478
Query: 414 PQQSGSLPEEGSK------PSNSCVLRETMVQASPSSKAQQ-----TPSAQDYGRGNIIS 462
P P +G + P L + + SP+S QQ P Q GR
Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRL--PSPTSAPQQPASQAAPPTQGQGR----- 531
Query: 463 PSRMLDKSPS--PASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDR 520
SR + P PA+ A PS + GPP++ + P
Sbjct: 532 QSRPVAGGPGAPPAARPPASPS--PQRQAGPPQATRQTSVSGPAP--------------- 574
Query: 521 PEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMP 570
P+ + A P P P G G R+ + A P R+ +T P P
Sbjct: 575 PKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVP-RTGPPTTQQPRP 623
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 42.4 bits (98), Expect = 0.002
Identities = 59/214 (27%), Positives = 78/214 (36%), Gaps = 36/214 (16%)
Query: 296 PQRGGPSFP-RESPRG---------PAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRET 345
PQR GP R P+G PAG Q P + P + + GR++
Sbjct: 474 PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533
Query: 346 -PAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQ 404
P G G R ASPSPQRQ G + V P P ++ GA GG Q
Sbjct: 534 RPVAGGPGAPPAARPPASPSPQRQAG-PPQATRQTSVSGP------APPKASGAPPGGQQ 586
Query: 405 QQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPS 464
+QG P + P +G P+ + + P + Q PS G G P
Sbjct: 587 RQG-PPQKPPGPAG--------PTRQASQAGPVPRTGPPTTQQPRPS----GPGPAGRPK 633
Query: 465 RMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEK 498
L + PS P A + GPP + K
Sbjct: 634 PQLAQKPSQDV-----PPPATAAAGGPPHPQLNK 662
Score = 37.4 bits (85), Expect = 0.053
Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 40/230 (17%)
Query: 356 PLRHAASPSPQRQGGWSTDGGGRL-LVFAPGREDEGGPAQSRGAGRGGPQQQGYMP-LEG 413
P + SP R T G L L ++ G PAQ R +GGP Q G P +G
Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478
Query: 414 PQQSGSLPEEGSK------PSNSCVLRETMVQASPSSKAQQ-----TPSAQDYGRGNIIS 462
P P +G + P L + + SP+S QQ P Q GR
Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRL--PSPTSAPQQPASQAAPPTQGQGR----- 531
Query: 463 PSRMLDKSPS--PASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDR 520
SR + P PA+ A PS + GPP++ + P
Sbjct: 532 QSRPVAGGPGAPPAARPPASPS--PQRQAGPPQATRQTSVSGPAP--------------- 574
Query: 521 PEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMP 570
P+ + A P P P G G R+ + A P R+ +T P P
Sbjct: 575 PKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVP-RTGPPTTQQPRP 623
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 41.2 bits (95), Expect = 0.004
Identities = 132/614 (21%), Positives = 200/614 (32%), Gaps = 90/614 (14%)
Query: 162 AQAHKARPSMGDWRPRSVDETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGD 221
A A A +G PR T PA A G + P + + + +
Sbjct: 575 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 634
Query: 222 LDRALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHA 281
+ +A GLQ +A + G L QG L P V+Q E
Sbjct: 635 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL----PGKTGPTVTQVKAEKQ-------- 682
Query: 282 VALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLW 341
+++ S E+ PA + T +A PA ARA
Sbjct: 683 -----------EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA--------- 722
Query: 342 GRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGR- 400
AKG+ G + AA+ + QR V P R + +RG
Sbjct: 723 ---PSAKGTISAPGKVVTAAAQAKQRSPS---------KVKPPVRNPQNSTVLARGPASV 770
Query: 401 ---GGPQQQGYMPLEGPQQ-SGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456
G GP++ SGS EE + ET+ Q PS K Q +A
Sbjct: 771 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA----ETLAQVKPSGKTHQIRAALAPA 826
Query: 457 RGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIK---RSPMDKVLRFARQ 513
+ SP + +P +G PS A + K S +E+ +P +
Sbjct: 827 KE---SPRKGAAPTPPGKTG----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 879
Query: 514 PLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-----ESTLYP 568
P L+ P + A P + PA + R A A E+ RS S E +
Sbjct: 880 PPLIFVDPNRSPAGPAAT----PAQ---AQAASTPRKARASESTARSSSSESEDEDVIPA 932
Query: 569 MPVLVP-----LAVAPQESHRTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLAS 623
L P + P R + +A +S S ++ + ++ AS
Sbjct: 933 TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPAS 992
Query: 624 CP--ESNLGPPRPVARRAGGPLARGRPSLVRQDAY-TRSDSEPSKHSAECD-------PR 673
P ++ L A A P+AR +PS A T + P S + P+
Sbjct: 993 LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1052
Query: 674 FPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYVAAGHAELAWTQEA 733
P V T ESSD + + S D EG ++ +G + L A
Sbjct: 1053 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAA 1112
Query: 734 PVSSGPLLSPVPKL 747
S +++P L
Sbjct: 1113 ESSEDDVVAPSQSL 1126
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 40.8 bits (94), Expect = 0.005
Identities = 73/264 (27%), Positives = 92/264 (34%), Gaps = 46/264 (17%)
Query: 193 EEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQGVDIP 252
+ G P A P G P+ S GD P + G Q G P
Sbjct: 893 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG--------P 944
Query: 253 LHVPDPKYRQDLVSQGGR--------EVYPYPSPLHAVALQSPLFVLTKETP---QRGGP 301
P P + L G+ + P P P V Q P T ET +RG P
Sbjct: 945 KGPPGPPGKDGLPGHPGQRGETGFQGKTGP-PGPGGVVGPQGP----TGETGPIGERGHP 999
Query: 302 SFP----RESPRGPAGLNTIQTGPVLEA-----GPARARAYIDRLLHLWGRETPA-KGSE 351
P + G AG + P + GPA R + + P KG E
Sbjct: 1000 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1059
Query: 352 GEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ------ 404
G QGP SP + G + G L PG + GPA +GA G GPQ
Sbjct: 1060 GPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1116
Query: 405 -QQGYMPLEGPQ-QSGSLPEEGSK 426
QG + L GP +GS E+G K
Sbjct: 1117 GVQGPVGLPGPAGPAGSPGEDGDK 1140
Score = 35.0 bits (79), Expect = 0.26
Identities = 37/135 (27%), Positives = 52/135 (38%), Gaps = 21/135 (15%)
Query: 306 ESPRGPAGLNTIQTGPVLEAGPA-----RARAYIDRLLHLWGRETPA--------KGSEG 352
+ P GP G + GP + GP+ + + + L GR+ P G+ G
Sbjct: 822 DGPEGPKG----RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 877
Query: 353 EQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLE 412
E+G A P P+ Q G + G R A G + GP + G G G P G +
Sbjct: 878 EKGARGVAGKPGPRGQRGPTGPRGSR---GARGPTGKPGPKGTSG-GDGPPGPPGERGPQ 933
Query: 413 GPQQSGSLPEEGSKP 427
GPQ P P
Sbjct: 934 GPQGPVGFPGPKGPP 948
Score = 33.5 bits (75), Expect = 0.77
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
Query: 4 PGGPPGSAGWDRRR-----LGARLRAAFAGLQELQGLRATQQERVRGALA-LQPPPAPAA 57
P GPPG G D R +G R AG + L G R T + +A + PP P
Sbjct: 632 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 691
Query: 58 PCGPHGLHGPEQQ 70
GP G GP Q
Sbjct: 692 NMGPQGEPGPPGQ 704
Score = 32.0 bits (71), Expect = 2.2
Identities = 45/170 (26%), Positives = 60/170 (35%), Gaps = 40/170 (23%)
Query: 256 PDPKYRQDLVSQGGRE-VYPYPSPLHAVALQSPLFVLTKETPQRG--------GPSFPRE 306
P P+ +Q + Q G E +P P + LQ L ++G GP P
Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG----LPGPPGEKGENGDVGPMGPPGP-P 1236
Query: 307 SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQ 366
PRGP G N GP GP + + G GE+G A +P P
Sbjct: 1237 GPRGPQGPNGAD-GP---QGPPGSVGSV--------------GGVGEKGEPGEAGNPGPP 1278
Query: 367 RQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGP 414
+ G G R G + E GP + G +G P G GP
Sbjct: 1279 GEAGVGGPKGER------GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1322
Score = 31.6 bits (70), Expect = 2.9
Identities = 36/120 (30%), Positives = 43/120 (35%), Gaps = 9/120 (7%)
Query: 300 GPSFPR--ESPRGPAGLNTIQTGPVLEAG---PARARAYIDRLLHLWGRETPAKGSEGEQ 354
GP PR + P GP G + P + G P A DR KG GE+
Sbjct: 571 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 630
Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGP 414
GP P G + G R L PG G RG G P Q G ++GP
Sbjct: 631 GPQGPPGPPGDDGMRGEDGEIGPRGL---PGEAGPRGLLGPRGT-PGAPGQPGMAGVDGP 686
Score = 30.0 bits (66), Expect = 8.5
Identities = 50/201 (24%), Positives = 67/201 (33%), Gaps = 32/201 (15%)
Query: 300 GPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRH 359
G P+ +P GP G GP E GPA + G +GE G
Sbjct: 1312 GDDGPKGNP-GPVGFPG-DPGPPGEPGPAG--------------QDGVGGDKGEDGDPGQ 1355
Query: 360 AASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQQS 417
P P + G G R A G E G ++G G P + G + +GP +
Sbjct: 1356 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP--A 1413
Query: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477
G EG + V Q P + Q P G + P K + G
Sbjct: 1414 GKPGPEGLRGIPGPVGE----QGLPGAAGQDGPP------GPMGPPGLPGLKGDPGSKGE 1463
Query: 478 FAHPSFAASLKMGPPKSKAEK 498
HP + GPP + EK
Sbjct: 1464 KGHPGLIGLI--GPPGEQGEK 1482
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 40.8 bits (94), Expect = 0.005
Identities = 73/264 (27%), Positives = 92/264 (34%), Gaps = 46/264 (17%)
Query: 193 EEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQGVDIP 252
+ G P A P G P+ S GD P + G Q G P
Sbjct: 842 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG--------P 893
Query: 253 LHVPDPKYRQDLVSQGGR--------EVYPYPSPLHAVALQSPLFVLTKETP---QRGGP 301
P P + L G+ + P P P V Q P T ET +RG P
Sbjct: 894 KGPPGPPGKDGLPGHPGQRGETGFQGKTGP-PGPGGVVGPQGP----TGETGPIGERGHP 948
Query: 302 SFP----RESPRGPAGLNTIQTGPVLEA-----GPARARAYIDRLLHLWGRETPA-KGSE 351
P + G AG + P + GPA R + + P KG E
Sbjct: 949 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1008
Query: 352 GEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ------ 404
G QGP SP + G + G L PG + GPA +GA G GPQ
Sbjct: 1009 GPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1065
Query: 405 -QQGYMPLEGPQ-QSGSLPEEGSK 426
QG + L GP +GS E+G K
Sbjct: 1066 GVQGPVGLPGPAGPAGSPGEDGDK 1089
Score = 35.0 bits (79), Expect = 0.26
Identities = 37/135 (27%), Positives = 52/135 (38%), Gaps = 21/135 (15%)
Query: 306 ESPRGPAGLNTIQTGPVLEAGPA-----RARAYIDRLLHLWGRETPA--------KGSEG 352
+ P GP G + GP + GP+ + + + L GR+ P G+ G
Sbjct: 771 DGPEGPKG----RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826
Query: 353 EQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLE 412
E+G A P P+ Q G + G R A G + GP + G G G P G +
Sbjct: 827 EKGARGVAGKPGPRGQRGPTGPRGSR---GARGPTGKPGPKGTSG-GDGPPGPPGERGPQ 882
Query: 413 GPQQSGSLPEEGSKP 427
GPQ P P
Sbjct: 883 GPQGPVGFPGPKGPP 897
Score = 33.5 bits (75), Expect = 0.77
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
Query: 4 PGGPPGSAGWDRRR-----LGARLRAAFAGLQELQGLRATQQERVRGALA-LQPPPAPAA 57
P GPPG G D R +G R AG + L G R T + +A + PP P
Sbjct: 581 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 640
Query: 58 PCGPHGLHGPEQQ 70
GP G GP Q
Sbjct: 641 NMGPQGEPGPPGQ 653
Score = 32.0 bits (71), Expect = 2.2
Identities = 45/170 (26%), Positives = 60/170 (35%), Gaps = 40/170 (23%)
Query: 256 PDPKYRQDLVSQGGRE-VYPYPSPLHAVALQSPLFVLTKETPQRG--------GPSFPRE 306
P P+ +Q + Q G E +P P + LQ L ++G GP P
Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG----LPGPPGEKGENGDVGPMGPPGP-P 1185
Query: 307 SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQ 366
PRGP G N GP GP + + G GE+G A +P P
Sbjct: 1186 GPRGPQGPNGAD-GP---QGPPGSVGSV--------------GGVGEKGEPGEAGNPGPP 1227
Query: 367 RQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGP 414
+ G G R G + E GP + G +G P G GP
Sbjct: 1228 GEAGVGGPKGER------GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1271
Score = 31.6 bits (70), Expect = 2.9
Identities = 36/120 (30%), Positives = 43/120 (35%), Gaps = 9/120 (7%)
Query: 300 GPSFPR--ESPRGPAGLNTIQTGPVLEAG---PARARAYIDRLLHLWGRETPAKGSEGEQ 354
GP PR + P GP G + P + G P A DR KG GE+
Sbjct: 520 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 579
Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGP 414
GP P G + G R L PG G RG G P Q G ++GP
Sbjct: 580 GPQGPPGPPGDDGMRGEDGEIGPRGL---PGEAGPRGLLGPRGT-PGAPGQPGMAGVDGP 635
Score = 30.0 bits (66), Expect = 8.5
Identities = 50/201 (24%), Positives = 67/201 (33%), Gaps = 32/201 (15%)
Query: 300 GPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRH 359
G P+ +P GP G GP E GPA + G +GE G
Sbjct: 1261 GDDGPKGNP-GPVGFPG-DPGPPGEPGPAG--------------QDGVGGDKGEDGDPGQ 1304
Query: 360 AASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQQS 417
P P + G G R A G E G ++G G P + G + +GP +
Sbjct: 1305 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP--A 1362
Query: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477
G EG + V Q P + Q P G + P K + G
Sbjct: 1363 GKPGPEGLRGIPGPVGE----QGLPGAAGQDGPP------GPMGPPGLPGLKGDPGSKGE 1412
Query: 478 FAHPSFAASLKMGPPKSKAEK 498
HP + GPP + EK
Sbjct: 1413 KGHPGLIGLI--GPPGEQGEK 1431
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 40.8 bits (94), Expect = 0.005
Identities = 73/264 (27%), Positives = 92/264 (34%), Gaps = 46/264 (17%)
Query: 193 EEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQGVDIP 252
+ G P A P G P+ S GD P + G Q G P
Sbjct: 881 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG--------P 932
Query: 253 LHVPDPKYRQDLVSQGGR--------EVYPYPSPLHAVALQSPLFVLTKETP---QRGGP 301
P P + L G+ + P P P V Q P T ET +RG P
Sbjct: 933 KGPPGPPGKDGLPGHPGQRGETGFQGKTGP-PGPGGVVGPQGP----TGETGPIGERGHP 987
Query: 302 SFP----RESPRGPAGLNTIQTGPVLEA-----GPARARAYIDRLLHLWGRETPA-KGSE 351
P + G AG + P + GPA R + + P KG E
Sbjct: 988 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1047
Query: 352 GEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ------ 404
G QGP SP + G + G L PG + GPA +GA G GPQ
Sbjct: 1048 GPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1104
Query: 405 -QQGYMPLEGPQ-QSGSLPEEGSK 426
QG + L GP +GS E+G K
Sbjct: 1105 GVQGPVGLPGPAGPAGSPGEDGDK 1128
Score = 35.0 bits (79), Expect = 0.26
Identities = 37/135 (27%), Positives = 52/135 (38%), Gaps = 21/135 (15%)
Query: 306 ESPRGPAGLNTIQTGPVLEAGPA-----RARAYIDRLLHLWGRETPA--------KGSEG 352
+ P GP G + GP + GP+ + + + L GR+ P G+ G
Sbjct: 810 DGPEGPKG----RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865
Query: 353 EQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLE 412
E+G A P P+ Q G + G R A G + GP + G G G P G +
Sbjct: 866 EKGARGVAGKPGPRGQRGPTGPRGSR---GARGPTGKPGPKGTSG-GDGPPGPPGERGPQ 921
Query: 413 GPQQSGSLPEEGSKP 427
GPQ P P
Sbjct: 922 GPQGPVGFPGPKGPP 936
Score = 33.5 bits (75), Expect = 0.77
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
Query: 4 PGGPPGSAGWDRRR-----LGARLRAAFAGLQELQGLRATQQERVRGALA-LQPPPAPAA 57
P GPPG G D R +G R AG + L G R T + +A + PP P
Sbjct: 620 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 679
Query: 58 PCGPHGLHGPEQQ 70
GP G GP Q
Sbjct: 680 NMGPQGEPGPPGQ 692
Score = 32.0 bits (71), Expect = 2.2
Identities = 45/170 (26%), Positives = 60/170 (35%), Gaps = 40/170 (23%)
Query: 256 PDPKYRQDLVSQGGRE-VYPYPSPLHAVALQSPLFVLTKETPQRG--------GPSFPRE 306
P P+ +Q + Q G E +P P + LQ L ++G GP P
Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG----LPGPPGEKGENGDVGPMGPPGP-P 1224
Query: 307 SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQ 366
PRGP G N GP GP + + G GE+G A +P P
Sbjct: 1225 GPRGPQGPNGAD-GP---QGPPGSVGSV--------------GGVGEKGEPGEAGNPGPP 1266
Query: 367 RQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGP 414
+ G G R G + E GP + G +G P G GP
Sbjct: 1267 GEAGVGGPKGER------GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1310
Score = 31.6 bits (70), Expect = 2.9
Identities = 36/120 (30%), Positives = 43/120 (35%), Gaps = 9/120 (7%)
Query: 300 GPSFPR--ESPRGPAGLNTIQTGPVLEAG---PARARAYIDRLLHLWGRETPAKGSEGEQ 354
GP PR + P GP G + P + G P A DR KG GE+
Sbjct: 559 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 618
Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGP 414
GP P G + G R L PG G RG G P Q G ++GP
Sbjct: 619 GPQGPPGPPGDDGMRGEDGEIGPRGL---PGEAGPRGLLGPRGT-PGAPGQPGMAGVDGP 674
Score = 30.0 bits (66), Expect = 8.5
Identities = 50/201 (24%), Positives = 67/201 (33%), Gaps = 32/201 (15%)
Query: 300 GPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRH 359
G P+ +P GP G GP E GPA + G +GE G
Sbjct: 1300 GDDGPKGNP-GPVGFPG-DPGPPGEPGPAG--------------QDGVGGDKGEDGDPGQ 1343
Query: 360 AASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQQS 417
P P + G G R A G E G ++G G P + G + +GP +
Sbjct: 1344 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP--A 1401
Query: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477
G EG + V Q P + Q P G + P K + G
Sbjct: 1402 GKPGPEGLRGIPGPVGE----QGLPGAAGQDGPP------GPMGPPGLPGLKGDPGSKGE 1451
Query: 478 FAHPSFAASLKMGPPKSKAEK 498
HP + GPP + EK
Sbjct: 1452 KGHPGLIGLI--GPPGEQGEK 1470
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 40.8 bits (94), Expect = 0.005
Identities = 43/134 (32%), Positives = 49/134 (36%), Gaps = 20/134 (14%)
Query: 299 GGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLR 358
G P FP PRGP G TGP+ G E G +GEQGP
Sbjct: 429 GAPGFP--GPRGPPGPQGA-TGPLGPKGQTG--------------EPGIAGFKGEQGPKG 471
Query: 359 HAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA--GRGGPQQQGYM-PLEGPQ 415
PQ G + + G R PG GP RGA RG P Q G P P
Sbjct: 472 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531
Query: 416 QSGSLPEEGSKPSN 429
+ G G K +N
Sbjct: 532 ERGPSGLAGPKGAN 545
Score = 32.3 bits (72), Expect = 1.7
Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 26/111 (23%)
Query: 298 RGGPSFPRES-PRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGP 356
RG P E+ P GPAG AGP A + AKG +GE G
Sbjct: 818 RGAPGERGETGPPGPAGF----------AGPPGADG-----------QPGAKGEQGEAGQ 856
Query: 357 LRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG----AGRGGP 403
A +P PQ G G + G GP + G AGR GP
Sbjct: 857 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGP 907
Score = 32.3 bits (72), Expect = 1.7
Identities = 38/129 (29%), Positives = 48/129 (37%), Gaps = 33/129 (25%)
Query: 299 GGPSFPRESPR-GPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357
G FP + R GP G N GP GP+ G++ P KG+ G+ GP
Sbjct: 894 GATGFPGAAGRVGPPGSNG-NPGPPGPPGPS-------------GKDGP-KGARGDSGPP 938
Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ----QQGYMPLE 412
A P Q G PG + E G GA G GPQ Q+G + L
Sbjct: 939 GRAGEPGLQGPAG------------PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986
Query: 413 GPQQSGSLP 421
G + P
Sbjct: 987 GQRGERGFP 995
Score = 32.0 bits (71), Expect = 2.2
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 4 PGGPPGSAGWDRRRLGARLRAAFAGL--QELQGLRATQQERVRGALALQPPPAPAAPCGP 61
P GPPG G LG A AG ++ G + + G + + PP PA GP
Sbjct: 166 PPGPPGPPG-----LGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 220
Query: 62 HGLHG 66
G G
Sbjct: 221 QGFQG 225
Score = 31.6 bits (70), Expect = 2.9
Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 28/104 (26%)
Query: 308 PRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQR 367
P GP GL G GPA A A+G++G+ GP A P P
Sbjct: 322 PMGPRGL----PGERGRTGPAGAAG--------------ARGNDGQPGP---AGPPGPVG 360
Query: 368 QGGWSTDGGGRLLVFAPGREDEGGPAQSRG-AGRGGPQQQGYMP 410
G G APG + E GP +RG G GP+ + P
Sbjct: 361 PAGGPGFPG------APGAKGEAGPTGARGPEGAQGPRGEPGTP 398
Score = 31.2 bits (69), Expect = 3.8
Identities = 37/120 (30%), Positives = 44/120 (36%), Gaps = 22/120 (18%)
Query: 300 GPSFPRESPRGPAGLNTIQTGPVL--EAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357
GP+ P P GPAG P EAGP T A+G EG QGP
Sbjct: 351 GPAGP-PGPVGPAGGPGFPGAPGAKGEAGP-----------------TGARGPEGAQGPR 392
Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQ 415
+P G S + G + A G G A + G RG P QG GP+
Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 452
Score = 30.4 bits (67), Expect = 6.5
Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 17/80 (21%)
Query: 4 PGGPPGSAGWDRRRLGARLR------AAFAGLQELQGLRATQQERV----------RGAL 47
P GP G G DR GA+ A G+Q QG R + E RG
Sbjct: 1078 PAGPTGKQG-DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1136
Query: 48 ALQPPPAPAAPCGPHGLHGP 67
LQ P P P G G GP
Sbjct: 1137 GLQGLPGPPGPSGDQGASGP 1156
Score = 30.0 bits (66), Expect = 8.5
Identities = 42/158 (26%), Positives = 53/158 (33%), Gaps = 34/158 (21%)
Query: 297 QRGGPSFPRE--SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQ 354
Q+G P ++ P+GP G GP E GP R G P +G +GE
Sbjct: 105 QKGEPGDIKDIVGPKGPPG----PQGPAGEQGPRGDRGDKGEK----GAPGP-RGRDGEP 155
Query: 355 GPLRHAASPSP---------------QRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG-A 398
G + P P Q GG+ GG L G GP G A
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215
Query: 399 GRGGPQ-------QQGYMPLEGPQQSGSLPEEGSKPSN 429
G GPQ + G + GP P KP +
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 253
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 40.8 bits (94), Expect = 0.005
Identities = 43/134 (32%), Positives = 49/134 (36%), Gaps = 20/134 (14%)
Query: 299 GGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLR 358
G P FP PRGP G TGP+ G E G +GEQGP
Sbjct: 360 GAPGFP--GPRGPPGPQGA-TGPLGPKGQTG--------------EPGIAGFKGEQGPKG 402
Query: 359 HAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA--GRGGPQQQGYM-PLEGPQ 415
PQ G + + G R PG GP RGA RG P Q G P P
Sbjct: 403 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 462
Query: 416 QSGSLPEEGSKPSN 429
+ G G K +N
Sbjct: 463 ERGPSGLAGPKGAN 476
Score = 32.3 bits (72), Expect = 1.7
Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 26/111 (23%)
Query: 298 RGGPSFPRES-PRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGP 356
RG P E+ P GPAG AGP A + AKG +GE G
Sbjct: 749 RGAPGERGETGPPGPAGF----------AGPPGADG-----------QPGAKGEQGEAGQ 787
Query: 357 LRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG----AGRGGP 403
A +P PQ G G + G GP + G AGR GP
Sbjct: 788 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGP 838
Score = 32.3 bits (72), Expect = 1.7
Identities = 38/129 (29%), Positives = 48/129 (37%), Gaps = 33/129 (25%)
Query: 299 GGPSFPRESPR-GPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357
G FP + R GP G N GP GP+ G++ P KG+ G+ GP
Sbjct: 825 GATGFPGAAGRVGPPGSNG-NPGPPGPPGPS-------------GKDGP-KGARGDSGPP 869
Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ----QQGYMPLE 412
A P Q G PG + E G GA G GPQ Q+G + L
Sbjct: 870 GRAGEPGLQGPAG------------PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917
Query: 413 GPQQSGSLP 421
G + P
Sbjct: 918 GQRGERGFP 926
Score = 32.0 bits (71), Expect = 2.2
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 4 PGGPPGSAGWDRRRLGARLRAAFAGL--QELQGLRATQQERVRGALALQPPPAPAAPCGP 61
P GPPG G LG A AG ++ G + + G + + PP PA GP
Sbjct: 97 PPGPPGPPG-----LGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 151
Query: 62 HGLHG 66
G G
Sbjct: 152 QGFQG 156
Score = 31.6 bits (70), Expect = 2.9
Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 28/104 (26%)
Query: 308 PRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQR 367
P GP GL G GPA A A+G++G+ GP A P P
Sbjct: 253 PMGPRGL----PGERGRTGPAGAAG--------------ARGNDGQPGP---AGPPGPVG 291
Query: 368 QGGWSTDGGGRLLVFAPGREDEGGPAQSRG-AGRGGPQQQGYMP 410
G G APG + E GP +RG G GP+ + P
Sbjct: 292 PAGGPGFPG------APGAKGEAGPTGARGPEGAQGPRGEPGTP 329
Score = 31.2 bits (69), Expect = 3.8
Identities = 37/120 (30%), Positives = 44/120 (36%), Gaps = 22/120 (18%)
Query: 300 GPSFPRESPRGPAGLNTIQTGPVL--EAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357
GP+ P P GPAG P EAGP T A+G EG QGP
Sbjct: 282 GPAGP-PGPVGPAGGPGFPGAPGAKGEAGP-----------------TGARGPEGAQGPR 323
Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQ 415
+P G S + G + A G G A + G RG P QG GP+
Sbjct: 324 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 383
Score = 30.4 bits (67), Expect = 6.5
Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 17/80 (21%)
Query: 4 PGGPPGSAGWDRRRLGARLR------AAFAGLQELQGLRATQQERV----------RGAL 47
P GP G G DR GA+ A G+Q QG R + E RG
Sbjct: 1009 PAGPTGKQG-DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1067
Query: 48 ALQPPPAPAAPCGPHGLHGP 67
LQ P P P G G GP
Sbjct: 1068 GLQGLPGPPGPSGDQGASGP 1087
Score = 30.0 bits (66), Expect = 8.5
Identities = 42/158 (26%), Positives = 53/158 (33%), Gaps = 34/158 (21%)
Query: 297 QRGGPSFPRE--SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQ 354
Q+G P ++ P+GP G GP E GP R G P +G +GE
Sbjct: 36 QKGEPGDIKDIVGPKGPPG----PQGPAGEQGPRGDRGDKGEK----GAPGP-RGRDGEP 86
Query: 355 GPLRHAASPSP---------------QRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG-A 398
G + P P Q GG+ GG L G GP G A
Sbjct: 87 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146
Query: 399 GRGGPQ-------QQGYMPLEGPQQSGSLPEEGSKPSN 429
G GPQ + G + GP P KP +
Sbjct: 147 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 40.8 bits (94), Expect = 0.005
Identities = 73/320 (22%), Positives = 102/320 (31%), Gaps = 29/320 (9%)
Query: 349 GSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGY 408
GS+G G P + S+ GG L G D G G + G
Sbjct: 516 GSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGT 575
Query: 409 MPLEGPQQSGSLPEEGSKPSNSC-VLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRML 467
L P+ G+ P E PS + T SP S + PS+++ + PS
Sbjct: 576 PSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFF 635
Query: 468 --DKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAH 525
P F P SL P + E K P A L+ H
Sbjct: 636 HPPTHPQETGSPFPSPEPPHSL---PTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPH 692
Query: 526 AAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGR--SCSESTLYPMPVLVPLAVAPQESH 583
P+ GRGGLQ P P S S ++L + VL+ +
Sbjct: 693 EGPE-----------VGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYS 741
Query: 584 RTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPL 643
+A LL + A+ H+R L S P + PR A G L
Sbjct: 742 SLAAFLAHRQFCGLLLARAKDGHQR------SPGPPGLPSPPAA----PRVPADAHAGLL 791
Query: 644 ARGRPSLVRQDAYTRSDSEP 663
+ + L+ DA +P
Sbjct: 792 SHAKTFLLAGDAQAEGKDDP 811
Score = 36.2 bits (82), Expect = 0.12
Identities = 54/228 (23%), Positives = 76/228 (33%), Gaps = 31/228 (13%)
Query: 284 LQSPLFVLTKETPQRGGP--SFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLW 341
LQ V + GGP +F + S PAG + + P++A +
Sbjct: 3616 LQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAV 3675
Query: 342 GRETP---AKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA 398
G P A+G+E P A P P QG G P
Sbjct: 3676 GSLAPGELARGTENGMKPATPKAKPGPSSQGS-------------------GSPRPGTKT 3716
Query: 399 GRGGPQQQGYMPLEGPQQS--GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456
G GG Q Q P G QS + P + S PS S +A S + A + G
Sbjct: 3717 G-GGSQPQ---PASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQG 3772
Query: 457 RGNIISPSRMLDKSPSPASGHFAHPSFAASL-KMGPPKSKAEKIKRSP 503
+ P + S G P+ + S+ G S +K R+P
Sbjct: 3773 PHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTP 3820
Score = 32.7 bits (73), Expect = 1.3
Identities = 123/581 (21%), Positives = 187/581 (32%), Gaps = 109/581 (18%)
Query: 131 MSDGGSCSLSTSCASVCSDHISPSLGSLL---PVAQAHKARPSMGDWRPRSVD------- 180
+ D +C+ S + A+ H+ SLG L P+ +A+ +G P S
Sbjct: 2079 VGDLAACAPSPTSAA----HMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGP 2134
Query: 181 ---ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASA 237
PAW P +G + + D G P ++T D P +
Sbjct: 2135 QQLLACSPAWAPLEEADGVQ---ATTDTGAEDSPVAPPSLTTSPCD---PKEA------- 2181
Query: 238 DAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQ 297
L G L QG PL P +P P + AV + +TP+
Sbjct: 2182 ---LAGCLLQGEGSPLEDPSS--------------WP-PGSVSAVTCTH-----SGDTPK 2218
Query: 298 RGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRL-LHLWGRETPAKGSEGEQGP 356
P +S + + P P A A + + G + G E + G
Sbjct: 2219 DSTLRIPEDSRK-----EKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAG- 2272
Query: 357 LRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQ 416
R P PQ +G R+ P P+ + G Q +P E P
Sbjct: 2273 -RGLPGPDPQSRGAPPHTNPDRM----PRGHSSYSPSNTARLGHREGQAVTAVPTEPPTL 2327
Query: 417 SGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASG 476
G+ P+ S +C+ E SSK + P + GR R+ S G
Sbjct: 2328 QGAGPD-----SPACLEGEM----GTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLG 2378
Query: 477 HFAHPSFAAS-LKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWD 535
PS AS + P+S ++P L P L R G P + +
Sbjct: 2379 RTTAPSSTASDFQSDSPQSHRNASHQTPQGDPL----GPQDLKQRSRGYKKKPAST---E 2431
Query: 536 PAHW----PTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALF 591
W P G + A PG S ++ + P AP E + A
Sbjct: 2432 NGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHR-----PHPGAPAEPSPAALPAQQ 2486
Query: 592 PFE--ASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPS 649
P E A ++ HR +S + R P + G P V + P A+G
Sbjct: 2487 PLEPLAQKCQPPRKKSHR-------VSGKER----PNHSRGDPSHVTQ---PPPAQGSKE 2532
Query: 650 LVRQDAYTRSDS--EPSKHSAECDPRFPSVIPETSEGESSD 688
++R S PS E D + P+ P + +
Sbjct: 2533 VLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDE 2573
>gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]
Length = 476
Score = 40.8 bits (94), Expect = 0.005
Identities = 67/242 (27%), Positives = 87/242 (35%), Gaps = 43/242 (17%)
Query: 189 PQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLD--RALPADTG-LQKASADAELLGLL 245
P +E+ + PG ED G W S G L + LPAD G L+ S DAE+ L
Sbjct: 48 PLPSEQCYQAPGGPEDRGPAWVG------SHGVLQHTQGLPADRGGLRPGSLDAEIDLLS 101
Query: 246 CQGVDIPLHVPDPKYRQDLVSQGGREVY-PYPSPLHAVALQSPLFVLTKETPQRGGPSFP 304
++ R D R+ Y P P P + P GGP+
Sbjct: 102 STLAELNGGRGHASRRPD------RQAYEPPPPPAYRTGSLKPNPASPLPASPYGGPT-- 153
Query: 305 RESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPS 364
PA T T AGPA + + G P +G+ GPL P
Sbjct: 154 ------PASYTTAST----PAGPAFP-VQVKVAQPVRGCGPPRRGASQASGPLPGPHFPL 202
Query: 365 PQRQGGWSTDGGGRLLVFAPG---REDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLP 421
P GR V+ PG + + G A+ AG GP +G GPQ S P
Sbjct: 203 P-----------GRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHGPQVPLSQP 251
Query: 422 EE 423
E
Sbjct: 252 PE 253
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 40.8 bits (94), Expect = 0.005
Identities = 68/270 (25%), Positives = 97/270 (35%), Gaps = 53/270 (19%)
Query: 189 PQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQG 248
P T+ PPG G P P + G P G+Q + L+GL +G
Sbjct: 734 PPGTQGMQGPPGPRGMQGPPH----PHGIQGG------PGSQGIQGPVSQGPLMGLNPRG 783
Query: 249 VDIPLHVPDPKYRQDLVSQGGREVYPY-----PSPLHAVALQSPLFVLTKET-------P 296
+ P P P+ Q QG +P P P + P + + P
Sbjct: 784 MQGP---PGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP 840
Query: 297 QRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGP 356
+G P + RGP G + Q P GP + + G++ PA+G QGP
Sbjct: 841 PQGSMLGPPQELRGPPGSQSQQGPPQGSLGPP-PQGGMQGPPGPQGQQNPARGPHPSQGP 899
Query: 357 L--RHAASP-------SPQRQGGWST------------DGGGRLLVFAPGREDEGGPAQS 395
+ + +P +P Q G ST GR+ PG+ GP +
Sbjct: 900 IPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQ----GPGPN 955
Query: 396 RGAGRGGP-QQQGYMPLEGPQQSGSLPEEG 424
+G RG P G M +QSG PE G
Sbjct: 956 KGDSRGPPNHHMGPMSERRHEQSGG-PEHG 984
Score = 40.0 bits (92), Expect = 0.008
Identities = 66/281 (23%), Positives = 96/281 (34%), Gaps = 38/281 (13%)
Query: 274 PYPSPLHAVALQSPLFVLTKETPQRGGPSFPR-ESPRGPAGLNTIQT--GPVLEAGPARA 330
P PLH P + + PQ PR + GP G+ GP+ GP
Sbjct: 637 PQGPPLHQGG-GGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGP 695
Query: 331 RAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEG 390
+ H+ +G G QG + P PQ G G + + PG
Sbjct: 696 QGSSGPQGHMG-----PQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQ 750
Query: 391 GPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTP 450
GP G +GGP QG ++GP G P G P +Q P + Q P
Sbjct: 751 GPPHPHGI-QGGPGSQG---IQGPVSQG--PLMGLNPRG--------MQGPPGPRENQGP 796
Query: 451 SAQDYGRGNIISPSRMLDKSPSPASGHFAH-------PSFAASLKMGPPKSK----AEKI 499
+ Q G+ P M + P P G H P ++ PP+ +++
Sbjct: 797 APQGMIMGH--PPQEM--RGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQEL 852
Query: 500 KRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWP 540
+ P + + Q L G P P + +PA P
Sbjct: 853 RGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGP 893
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 40.4 bits (93), Expect = 0.006
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%)
Query: 348 KGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQG 407
+G G P R +P P+ + G+S G AP G P SRG GRGGP QQ
Sbjct: 408 RGGRGAPPPPRGRGAPPPRGRAGYSQRG-------AP----LGPPRGSRG-GRGGPAQQ- 454
Query: 408 YMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456
+ GS G++ N R+ P SK +QT + Q++G
Sbjct: 455 ------QRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWG 497
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 40.4 bits (93), Expect = 0.006
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%)
Query: 348 KGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQG 407
+G G P R +P P+ + G+S G AP G P SRG GRGGP QQ
Sbjct: 509 RGGRGAPPPPRGRGAPPPRGRAGYSQRG-------AP----LGPPRGSRG-GRGGPAQQ- 555
Query: 408 YMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456
+ GS G++ N R+ P SK +QT + Q++G
Sbjct: 556 ------QRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWG 598
>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
[Homo sapiens]
Length = 532
Score = 40.4 bits (93), Expect = 0.006
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%)
Query: 348 KGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQG 407
+G G P R +P P+ + G+S G AP G P SRG GRGGP QQ
Sbjct: 405 RGGRGAPPPPRGRGAPPPRGRAGYSQRG-------AP----LGPPRGSRG-GRGGPAQQ- 451
Query: 408 YMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456
+ GS G++ N R+ P SK +QT + Q++G
Sbjct: 452 ------QRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWG 494
>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
[Homo sapiens]
Length = 633
Score = 40.4 bits (93), Expect = 0.006
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%)
Query: 348 KGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQG 407
+G G P R +P P+ + G+S G AP G P SRG GRGGP QQ
Sbjct: 506 RGGRGAPPPPRGRGAPPPRGRAGYSQRG-------AP----LGPPRGSRG-GRGGPAQQ- 552
Query: 408 YMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456
+ GS G++ N R+ P SK +QT + Q++G
Sbjct: 553 ------QRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWG 595
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 40.0 bits (92), Expect = 0.008
Identities = 129/579 (22%), Positives = 191/579 (32%), Gaps = 92/579 (15%)
Query: 162 AQAHKARPSMGDWRPRSVDETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGD 221
A A A +G PR T PA A G + P + + + +
Sbjct: 652 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 711
Query: 222 LDRALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHA 281
+ +A GLQ +A + G L QG L P V+Q E
Sbjct: 712 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL----PGKTGPTVTQVKAEKQ-------- 759
Query: 282 VALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLW 341
+++ S E+ PA + T +A PA ARA
Sbjct: 760 -----------EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA--------- 799
Query: 342 GRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGR- 400
AKG+ G + AA+ + QR V P R + +RG
Sbjct: 800 ---PSAKGTISAPGKVVTAAAQAKQRSPS---------KVKPPVRNPQNSTVLARGPASV 847
Query: 401 ---GGPQQQGYMPLEGPQQ-SGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456
G GP++ SGS EE + ET+ Q PS K Q +A
Sbjct: 848 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA----ETLAQVKPSGKTHQIRAALAPA 903
Query: 457 RGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIK---RSPMDKVLRFARQ 513
+ SP + +P +G PS A + K S +E+ +P +
Sbjct: 904 KE---SPRKGAAPTPPGKTG----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 956
Query: 514 PLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-----ESTLYP 568
P L+ P + A P + PA + R A A E+ RS S E +
Sbjct: 957 PPLIFVDPNRSPAGPAAT----PAQ---AQAASTPRKARASESTARSSSSESEDEDVIPA 1009
Query: 569 MPVLVP-----LAVAPQESHRTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLAS 623
L P + P R + +A +S S ++ + ++ AS
Sbjct: 1010 TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPAS 1069
Query: 624 CP--ESNLGPPRPVARRAGGPLARGRPSLVRQDAY-TRSDSEPSKHSAECD-------PR 673
P ++ L A A P+AR +PS A T + P S + P+
Sbjct: 1070 LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1129
Query: 674 FPSVIPETSEGESSDHTTNRFGDRESSSSDEEG--GAQS 710
P V T ESSD + + S D EG GA+S
Sbjct: 1130 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1168
Score = 30.8 bits (68), Expect = 5.0
Identities = 67/300 (22%), Positives = 102/300 (34%), Gaps = 54/300 (18%)
Query: 324 EAGPARARAYI---DRLLHLWGRETPAKGSEGE---QGPLRHAASPSPQRQGGWSTDGG- 376
E PA R+ + +++L + PAKG+ G+ P A + + Q + G +
Sbjct: 281 EEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSE 340
Query: 377 -----------------GRLLVFAPGREDEGGPAQS-------RGAGRGGPQQQGYMPLE 412
L A G+ + G A + +GA P + G P
Sbjct: 341 SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG--PAV 398
Query: 413 GPQQSGSLPEEGSKPSN-SCVLRETMVQASPSSKAQQT-----PSAQDYGRGNIISPSRM 466
Q+G E+ S S E QA PS KA Q P+ + +G +P R
Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRK 458
Query: 467 LDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLL-----LLDRP 521
P+ A + S E + +V + P + + P
Sbjct: 459 T--GPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516
Query: 522 EGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQE 581
G A P P + PA P+ + G WE S SE + VP AVAP +
Sbjct: 517 LGKGAGPVPPGKVGPAT-PSAQVG-------KWEEDSESSSEESSDSSDGEVPTAVAPAQ 568
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 40.0 bits (92), Expect = 0.008
Identities = 129/579 (22%), Positives = 191/579 (32%), Gaps = 92/579 (15%)
Query: 162 AQAHKARPSMGDWRPRSVDETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGD 221
A A A +G PR T PA A G + P + + + +
Sbjct: 575 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 634
Query: 222 LDRALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHA 281
+ +A GLQ +A + G L QG L P V+Q E
Sbjct: 635 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL----PGKTGPTVTQVKAEKQ-------- 682
Query: 282 VALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLW 341
+++ S E+ PA + T +A PA ARA
Sbjct: 683 -----------EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA--------- 722
Query: 342 GRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGR- 400
AKG+ G + AA+ + QR V P R + +RG
Sbjct: 723 ---PSAKGTISAPGKVVTAAAQAKQRSPS---------KVKPPVRNPQNSTVLARGPASV 770
Query: 401 ---GGPQQQGYMPLEGPQQ-SGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456
G GP++ SGS EE + ET+ Q PS K Q +A
Sbjct: 771 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA----ETLAQVKPSGKTHQIRAALAPA 826
Query: 457 RGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIK---RSPMDKVLRFARQ 513
+ SP + +P +G PS A + K S +E+ +P +
Sbjct: 827 KE---SPRKGAAPTPPGKTG----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 879
Query: 514 PLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-----ESTLYP 568
P L+ P + A P + PA + R A A E+ RS S E +
Sbjct: 880 PPLIFVDPNRSPAGPAAT----PAQ---AQAASTPRKARASESTARSSSSESEDEDVIPA 932
Query: 569 MPVLVP-----LAVAPQESHRTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLAS 623
L P + P R + +A +S S ++ + ++ AS
Sbjct: 933 TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPAS 992
Query: 624 CP--ESNLGPPRPVARRAGGPLARGRPSLVRQDAY-TRSDSEPSKHSAECD-------PR 673
P ++ L A A P+AR +PS A T + P S + P+
Sbjct: 993 LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1052
Query: 674 FPSVIPETSEGESSDHTTNRFGDRESSSSDEEG--GAQS 710
P V T ESSD + + S D EG GA+S
Sbjct: 1053 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1091
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 40.0 bits (92), Expect = 0.008
Identities = 65/269 (24%), Positives = 100/269 (37%), Gaps = 42/269 (15%)
Query: 467 LDKSPSPAS----GHFAHPSFAASLKMGPPKSKAEKIKRSPMDK-------VLRFARQPL 515
L+K P+P G A +++L+ P +++AE + MD+ + +Q L
Sbjct: 602 LEKRPNPEKVVEEGREAGEMESSTLQESP-RARAEAVLLHEMDEDDLANALIWPEIQQEL 660
Query: 516 LLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPL 575
+++ E + P P+L+ P P L P + E PG S +P PV PL
Sbjct: 661 KIIESEEELSSLPPPALKTSPIQ-PILESSLG--PFIPSEPPGSLPCGS--FPAPVSTPL 715
Query: 576 AVAPQESHRTSAQA---------------LFPFEASLLT-SVARRKHRRWQSTVEISARA 619
V ++ S Q L P ASL + + Q+TVE+
Sbjct: 716 EVWTRDPANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKASPQATVEVGG-- 773
Query: 620 RLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSDSEPS-KHSAECDPRFPSVI 678
NL PP P A PL P L+ + R DS + D
Sbjct: 774 ------PGNLSPPLPPAPPPPTPLEESTPVLLSKGGPEREDSSRKLRTDLYIDQLKSQDS 827
Query: 679 PETSEGESSDHTTNRFGDRESSSSDEEGG 707
PE S + T R D+++S + G
Sbjct: 828 PEISSLCQGEEATPRHSDKQNSKNAASEG 856
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,499,058
Number of Sequences: 37866
Number of extensions: 2323097
Number of successful extensions: 10068
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 353
Number of HSP's that attempted gapping in prelim test: 8776
Number of HSP's gapped (non-prelim): 1722
length of query: 774
length of database: 18,247,518
effective HSP length: 110
effective length of query: 664
effective length of database: 14,082,258
effective search space: 9350619312
effective search space used: 9350619312
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.