BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo sapiens] (774 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo... 1576 0.0 gi|24158478 dapper 1 isoform 1 [Homo sapiens] 179 1e-44 gi|118498364 dapper 1 isoform 2 [Homo sapiens] 105 1e-22 gi|182507165 thymus expressed gene 3-like [Homo sapiens] 84 6e-16 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 52 2e-06 gi|144953905 hypothetical protein LOC55138 [Homo sapiens] 52 2e-06 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 49 2e-05 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 47 9e-05 gi|110832843 TBP-associated factor 4 [Homo sapiens] 46 2e-04 gi|150170670 piccolo isoform 2 [Homo sapiens] 46 2e-04 gi|150378539 piccolo isoform 1 [Homo sapiens] 46 2e-04 gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 45 2e-04 gi|19924097 synapsin I isoform Ib [Homo sapiens] 44 6e-04 gi|19924099 synapsin I isoform Ia [Homo sapiens] 42 0.002 gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 41 0.004 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 41 0.005 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 41 0.005 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 41 0.005 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 41 0.005 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 41 0.005 gi|188536004 zinc finger protein 469 [Homo sapiens] 41 0.005 gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens] 41 0.005 gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 41 0.005 gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 40 0.006 gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 40 0.006 gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 40 0.006 gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 40 0.006 gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 40 0.008 gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 40 0.008 gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 40 0.008 >gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo sapiens] Length = 774 Score = 1576 bits (4080), Expect = 0.0 Identities = 774/774 (100%), Positives = 774/774 (100%) Query: 1 MWTPGGPPGSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCG 60 MWTPGGPPGSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCG Sbjct: 1 MWTPGGPPGSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCG 60 Query: 61 PHGLHGPEQQLEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDS 120 PHGLHGPEQQLEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDS Sbjct: 61 PHGLHGPEQQLEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDS 120 Query: 121 DSRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD 180 DSRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD Sbjct: 121 DSRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD 180 Query: 181 ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAE 240 ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAE Sbjct: 181 ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAE 240 Query: 241 LLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGG 300 LLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGG Sbjct: 241 LLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGG 300 Query: 301 PSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHA 360 PSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHA Sbjct: 301 PSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHA 360 Query: 361 ASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSL 420 ASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSL Sbjct: 361 ASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSL 420 Query: 421 PEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH 480 PEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH Sbjct: 421 PEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH 480 Query: 481 PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWP 540 PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWP Sbjct: 481 PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWP 540 Query: 541 TGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALFPFEASLLTS 600 TGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALFPFEASLLTS Sbjct: 541 TGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALFPFEASLLTS 600 Query: 601 VARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSD 660 VARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSD Sbjct: 601 VARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSD 660 Query: 661 SEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYV 720 SEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYV Sbjct: 661 SEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYV 720 Query: 721 AAGHAELAWTQEAPVSSGPLLSPVPKLCRIKASKALKKKIRRFQPTALKVMTMV 774 AAGHAELAWTQEAPVSSGPLLSPVPKLCRIKASKALKKKIRRFQPTALKVMTMV Sbjct: 721 AAGHAELAWTQEAPVSSGPLLSPVPKLCRIKASKALKKKIRRFQPTALKVMTMV 774 >gi|24158478 dapper 1 isoform 1 [Homo sapiens] Length = 836 Score = 179 bits (453), Expect = 1e-44 Identities = 241/872 (27%), Positives = 348/872 (39%), Gaps = 176/872 (20%) Query: 9 GSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPE 68 G A +R+R R A AGL EL+ LR Q+ VRGAL AAP L Sbjct: 35 GEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAA 94 Query: 69 QQ-------LEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSD 121 Q+ LE + L++QL+ LR++D GL L +LD QIS L+LDV S E L++D Sbjct: 95 QRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETD 154 Query: 122 SRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDE 181 SRPSSGFYE+SDG S SLS S SV S+ +S S S +A S+ D P+S D Sbjct: 155 SRPSSGFYELSDGASGSLSNSSNSVFSECLS-SCHSSTCFCSPLEATLSLSDGCPKSADL 213 Query: 182 TTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAEL 241 + ++ E+ A G+V R +ST + Sbjct: 214 IGLLEYKEGHCEDQA--SGAV-----------CRSLSTPQFN------------------ 242 Query: 242 LGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGP 301 +D+ V +PKY+ DLVS+ G +VY YPSPLHAVA+QSP+F+L G P Sbjct: 243 ------SLDVIADV-NPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLC----LTGNP 291 Query: 302 SFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGE-------Q 354 RE R + I G L+A + + + LW P+ + + Q Sbjct: 292 L--REEDRLGNHASDICGGSELDA--VKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQ 347 Query: 355 GPLRHAASPSPQRQGGWSTDGG----GRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMP 410 + P+ G G + V APG +G + + + G Sbjct: 348 KKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPS 407 Query: 411 LEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKS 470 L + S P++ SK S + SK P G + + S+ L K+ Sbjct: 408 LN--NGTFSPPKQWSKESKA---------EQAESKRVPLPEGCPSGAASDLQ-SKHLPKT 455 Query: 471 PSPASGHFAH---------PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRP 521 PAS A P +A L PK E R P QPL + + Sbjct: 456 AKPASQEHARCSAIGTGESPKESAQLSGASPK---ESPSRGPAPPQENKVVQPLKKMSQK 512 Query: 522 EGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-ESTLYPMPVLVP------ 574 P + +P ++ RPAL +++ G S S E +P Sbjct: 513 NSLQGVPPATPPLLSTAFP-----VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 567 Query: 575 --------LAVAPQESHRTSAQALFPFEASLLT----SVARRKHRRWQSTVEISARARLA 622 + V S + AL E L T + A K R+ ++ + + + A Sbjct: 568 RLHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKA 627 Query: 623 SC--------PESNL-GPPRPVARRAGGPL-ARGRPSLVRQDAYTRSD------------ 660 S PE+ + G P RAG GR ++V + + R+D Sbjct: 628 SSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISY 687 Query: 661 ---------------------------------SEPSKHSAECDPRFPSVIPETSEGESS 687 + S++SAEC+ F S + +TSE E S Sbjct: 688 EEALRRARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQS 747 Query: 688 DHTTNRFGDRESSSSDEEGGAQS---RDCDLALGYVAAGHAELAWTQEAPVSSGPLL--S 742 ++TTN FGD ESS S+ E +S D + + G + ++ T + P L Sbjct: 748 NYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLI---WSQFVQTLPIQTVTAPDLHNH 804 Query: 743 PVPKLCRIKASKALKKKIRRFQPTALKVMTMV 774 P +IKAS LKKKI RF+ +LK+MT V Sbjct: 805 PAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836 >gi|118498364 dapper 1 isoform 2 [Homo sapiens] Length = 799 Score = 105 bits (263), Expect = 1e-22 Identities = 77/179 (43%), Positives = 98/179 (54%), Gaps = 8/179 (4%) Query: 9 GSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPE 68 G A +R+R R A AGL EL+ LR Q+ VRGAL AAP L Sbjct: 35 GEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAA 94 Query: 69 QQ-------LEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSD 121 Q+ LE + L++QL+ LR++D GL L +LD QIS L+LDV S E L++D Sbjct: 95 QRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETD 154 Query: 122 SRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVD 180 SRPSSGFYE+SDG S SLS S SV S+ +S S S +A S+ D P+S D Sbjct: 155 SRPSSGFYELSDGASGSLSNSSNSVFSECLS-SCHSSTCFCSPLEATLSLSDGCPKSAD 212 Score = 99.0 bits (245), Expect = 1e-20 Identities = 155/617 (25%), Positives = 232/617 (37%), Gaps = 130/617 (21%) Query: 257 DPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNT 316 +PKY+ DLVS+ G +VY YPSPLHAVA+QSP+F+L G P RE R + Sbjct: 214 NPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLC----LTGNPL--REEDRLGNHASD 267 Query: 317 IQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGE-------QGPLRHAASPSPQRQG 369 I G L+A + + + LW P+ + + Q + P+ Sbjct: 268 ICGGSELDA--VKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSV 325 Query: 370 GWSTDGG----GRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGS 425 G G + V APG +G + + + G L + S P++ S Sbjct: 326 NADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLN--NGTFSPPKQWS 383 Query: 426 KPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAH----- 480 K S + SK P G + + S+ L K+ PAS A Sbjct: 384 KESKA---------EQAESKRVPLPEGCPSGAASDLQ-SKHLPKTAKPASQEHARCSAIG 433 Query: 481 ----PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDP 536 P +A L PK E R P QPL + + P + Sbjct: 434 TGESPKESAQLSGASPK---ESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLS 490 Query: 537 AHWPTGRGGLQRRPALAWEAPGRSCS-ESTLYPMPVLVP--------------LAVAPQE 581 +P ++ RPAL +++ G S S E +P + V Sbjct: 491 TAFP-----VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNS 545 Query: 582 SHRTSAQALFPFEASLLT----SVARRKHRRWQSTVEISARARLASC--------PESNL 629 S + AL E L T + A K R+ ++ + + + AS PE+ + Sbjct: 546 SLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGV 605 Query: 630 -GPPRPVARRAGGPL-ARGRPSLVRQDAYTRSD--------------------------- 660 G P RAG GR ++V + + R+D Sbjct: 606 PGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENV 665 Query: 661 ------------------SEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSS 702 + S++SAEC+ F S + +TSE E S++TTN FGD ESS S Sbjct: 666 GLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVS 725 Query: 703 DEEGGAQS---RDCDLALGYVAAGHAELAWTQEAPVSSGPLL--SPVPKLCRIKASKALK 757 + E +S D + + G + ++ T + P L P +IKAS LK Sbjct: 726 EGEFVGESTTTSDSEESGGLI---WSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLK 782 Query: 758 KKIRRFQPTALKVMTMV 774 KKI RF+ +LK+MT V Sbjct: 783 KKILRFRSGSLKLMTTV 799 >gi|182507165 thymus expressed gene 3-like [Homo sapiens] Length = 629 Score = 83.6 bits (205), Expect = 6e-16 Identities = 205/794 (25%), Positives = 270/794 (34%), Gaps = 209/794 (26%) Query: 14 DRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPEQQLEA 73 +R RL L + AGL EL LR Q+ RV+ AL L P A ++ A Sbjct: 12 ERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAA 71 Query: 74 A---LAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSDSRPSSGFYE 130 A AAL+EQL L GL L Q Q+ L L+ G L+ +S SSGFYE Sbjct: 72 ARRAAAALEEQLEALP----GLVWDLGQ---QLGDLSLESG-----GLEQESGRSSGFYE 119 Query: 131 --MSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDETTVPAWR 188 S GG S ++ S S G L P + R RP+S+ + + Sbjct: 120 DPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGP----SEPRGIYASERPKSLGDAS----- 170 Query: 189 PQATEE-GARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQ 247 P A E GAR A P P P + G +A + AE Sbjct: 171 PSAPEVVGAR-------AAVPRSFSAPYPTAGGSAG---------PEACSSAE------- 207 Query: 248 GVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKET--PQRGGPSFPR 305 + + PSPLHAVA++SP T P GG P Sbjct: 208 ------------------RRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPL 249 Query: 306 ES-------PRGPAGLNTIQTGPV-LEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357 + R G +T P + GP R + R+ P S G Sbjct: 250 DGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSV---------RQRPPDASPSP-GSA 299 Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQS 417 R A PS +R GG T +A E E P P Sbjct: 300 RPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE--------------------PAAP 339 Query: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477 + P P+ ++ KAQ P AQ RG P R + P Sbjct: 340 PAAPSPPDSPAEGRLV-----------KAQYIPGAQAATRG---LPGRAARRKP------ 379 Query: 478 FAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPA 537 PP ++ +++SP + R A + R A A+ + Sbjct: 380 -------------PPLTRGRSVEQSPPRERPRAAGR------RGRMAEASGR-------- 412 Query: 538 HWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLA-----VAPQESHRTSAQALFP 592 RG + R A RS SE++L VP A +E R P Sbjct: 413 -----RGSPRARKA------SRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGP 461 Query: 593 FEASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVR 652 A L + A RRW+ST EI A + P P AR G + P Sbjct: 462 --APTLAAQAAGSCRRWRSTAEIDA------ADGRRVRPRAPAARVPGPGPSPSAPQRRL 513 Query: 653 QDAYTRSDSEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGA---Q 709 SDSE S P G + +G+ ESS+S+ E A Sbjct: 514 LYGCAGSDSECSAGRLG---------PLGRRGPAGG-VGGGYGESESSASEGESPAFSSA 563 Query: 710 SRDCDLALGYVAAGHAELAWTQEAPVSS---------GPLLSPVPKLCRIKASKALKKKI 760 S D D G L W Q+ ++ G P +IKAS ALKKKI Sbjct: 564 SSDSD--------GSGGLVWPQQLVAATAASGGGAGAGAPAGPAKVFVKIKASHALKKKI 615 Query: 761 RRFQPTALKVMTMV 774 RF+ +LKVMT V Sbjct: 616 LRFRSGSLKVMTTV 629 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 52.0 bits (123), Expect = 2e-06 Identities = 90/337 (26%), Positives = 119/337 (35%), Gaps = 75/337 (22%) Query: 294 ETPQRGGPSFPRESP------RGPAGLNTIQTGPVLEAGPARARAYIDRL----LHLWGR 343 E+ R GP+ P R P NT GPV G A L L + Sbjct: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNT-SPGPVSSPGRASGTTRPGPLGQKGLRISAE 130 Query: 344 ETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAG---- 399 ET A+G E P R A S +R T PG +SR AG Sbjct: 131 ETVARGKATE-APKRSALSAGARRDTSGPT----------PGTPSPAMARRSRAAGTEVG 179 Query: 400 --RGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGR 457 R P + P EGP++S S E S PS A++ PSA G Sbjct: 180 LPRPAPSARPRPPTEGPRKSVSSASEHS-------------TTEPSPAARRRPSA---GG 223 Query: 458 GNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLL 517 G SR L S +P S P+ + G P++ A P K L+ R P + Sbjct: 224 GLQRPASRSLSSSATPLSS----PARSGPSARGTPRAPAH--PSQPKPKGLQALRPPQVT 277 Query: 518 LDRPEGAH----------AAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSE---- 563 R + A A P PS P+ P+ LQ P+ P ++ + Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS----LQTLPSPPATPPSQATTSLGSP 333 Query: 564 -----STLYPMPVLVPLAVAPQESHRTSAQALFPFEA 595 + P P L PLA P ++ A AL P +A Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQA--PPALALPPLQA 368 Score = 33.5 bits (75), Expect = 0.77 Identities = 90/384 (23%), Positives = 119/384 (30%), Gaps = 57/384 (14%) Query: 123 RPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDET 182 RPS+G + S SLS+S + S S P A AH ++P +P+ + Sbjct: 218 RPSAGG-GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-----KPKGLQAL 271 Query: 183 TVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELL 242 P P +DA G P++T P+ + SA L Sbjct: 272 RPPQVTPPR-----------KDAAPALGPLSSSPLAT-------PSPSAPPSPSAPPSL- 312 Query: 243 GLLCQGVDIPLHVPDPKYRQDLVS---QGGREVYPYPSPLHAVALQSPLFVLTKETPQRG 299 Q + P P + L S Q P P PL +A P P Sbjct: 313 ----QTLPSPPATPPSQATTSLGSPTLQATHSFLPSP-PLSPLATPPPQAPPALALPPLQ 367 Query: 300 GPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRH 359 P P SP P+ P A LL P S Q P Sbjct: 368 APPSPPASP---------PLSPLATPSPQAPNALAVHLLQAPFSPPP---SPPVQAPFSP 415 Query: 360 AASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGS 419 ASP P L P + PA + P Q PL P + Sbjct: 416 PASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474 Query: 420 LPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFA 479 P + P+ A+P +A +P A G+ SPS L SP A Sbjct: 475 KPPPQAPPA----------LATPPLQALPSPPASFPGQAPF-SPSASLPMSPLATPPPQA 523 Query: 480 HPSFAASLKMGPPKSKAEKIKRSP 503 P AA L PP A ++P Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAP 547 >gi|144953905 hypothetical protein LOC55138 [Homo sapiens] Length = 464 Score = 52.0 bits (123), Expect = 2e-06 Identities = 88/371 (23%), Positives = 132/371 (35%), Gaps = 61/371 (16%) Query: 337 LLHLWGRETPAKGSEGEQGP------LRHAASPSP---------------QRQGGWSTDG 375 LLH++ R+ P K ++G LR A+ P P R +D Sbjct: 117 LLHIFSRKPPEKPLPNQKGSTESSDYLRVASGPMPVHTTSKRPRVDPVLSDRSATEMSDR 176 Query: 376 GGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRE 435 G L +P R+ + S G +P + G P KP++S Sbjct: 177 GSVLASLSPLRKASLSSSSSLGPKERQTGAAADIPQTAVRHQGPEPLLVVKPTHS----- 231 Query: 436 TMVQASPSSKAQQTPSA--QDYGRGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPK 493 SP+ ++ P A + +G +SP DK P+ S P+ SL +G Sbjct: 232 -----SPAGGCREVPQAASKTHGLLQAVSPQAQ-DKRPAVTSQP-CPPAATHSLGLGSNL 284 Query: 494 SKAEKIKRS---PMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRP 550 S KRS P+ L F ++P L G P+ +++ P LQ P Sbjct: 285 SFGPGAKRSAPAPIQACLNFPKKPRL------GPFQIPESAIQGGELGAPEN---LQPPP 335 Query: 551 ALAWEAPGRSCSESTLYPMPVL------------VPLAVAPQESHRTSAQALFPFEASLL 598 A P S T P VL +P A A SH +A L Sbjct: 336 AATELGPRTSPQTGTRTPAQVLSGDRQPPHSRPCLPTAQACTMSHHPAAS--HDGAQPLR 393 Query: 599 TSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTR 658 R ++ RW S++ + P + L V+ ++ GP R PS++ +D Sbjct: 394 VLFRRLENGRWSSSLLTAPSFHSPEKPGAFLAQSPHVSEKSEGPCVRVPPSVLYEDLQVP 453 Query: 659 SDSEPSKHSAE 669 S SE S E Sbjct: 454 SSSEDSDSDLE 464 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 48.5 bits (114), Expect = 2e-05 Identities = 81/303 (26%), Positives = 108/303 (35%), Gaps = 57/303 (18%) Query: 295 TPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQ 354 T R S P S RG T P + P RA T G G++ Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG------------TTRPGPLGQK 132 Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPA----------QSRGAG----- 399 G LR +A + R G +T+ R + A R D GP +SR AG Sbjct: 133 G-LRISAEETVAR--GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189 Query: 400 -RGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRG 458 R P + P EGP++S S E S PS A++ PSA G G Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHS-------------TTEPSPAARRRPSA---GGG 233 Query: 459 NIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLL 518 SR L S +P S P+ + G P++ A P K L+ R P + Sbjct: 234 LQRPASRSLSSSATPLSS----PARSGPSARGTPRAPAH--PSQPKPKGLQALRPPQVTP 287 Query: 519 DRPEGAHAAPQPSLEWDPAHWPTGRGGLQRR--PALAWEAPGRSCSESTLYPMPVLVPLA 576 R + A A L P P+ LQ + P L S + P+P+ P Sbjct: 288 PRKDAAPAL--GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345 Query: 577 VAP 579 AP Sbjct: 346 SAP 348 Score = 35.4 bits (80), Expect = 0.20 Identities = 96/391 (24%), Positives = 122/391 (31%), Gaps = 41/391 (10%) Query: 123 RPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPS---MGDWRPRSV 179 RPS+G + S SLS+S + S S P A AH ++P + RP V Sbjct: 227 RPSAGG-GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285 Query: 180 D---ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTG-DLDRALPADTGLQKA 235 + PA P ++ A P S Q T P S+ A P Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345 Query: 236 SADAELLGLLCQGVDIPLHVPDPKYRQDLVS---QGGREVYPYPSPLHAVALQSPLFVLT 292 SA L Q + P P + L S Q P P PL +A P Sbjct: 346 SAPPSL-----QTLPSPPATPPSQATTSLGSPTLQATHSFLPSP-PLSPLATPPPQAPPA 399 Query: 293 KETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEG 352 P P P SP P+ P A LL P S Sbjct: 400 LALPPLQAPPSPPASP---------PLSPLATPSPQAPNALAVHLLQAPFSPPP---SPP 447 Query: 353 EQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLE 412 Q P ASP P L P + PA + P Q PL Sbjct: 448 VQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506 Query: 413 GPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPS 472 P + P + P+ A+P +A +P A G+ SPS L SP Sbjct: 507 APPLQLAKPPPQAPPA----------LATPPLQALPSPPASFPGQAPF-SPSASLPMSPL 555 Query: 473 PASGHFAHPSFAASLKMGPPKSKAEKIKRSP 503 A P AA L PP A ++P Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 46.6 bits (109), Expect = 9e-05 Identities = 84/304 (27%), Positives = 112/304 (36%), Gaps = 62/304 (20%) Query: 295 TPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQ 354 T R S P S RG T P + P RA T G G++ Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG------------TTRPGPLGQK 132 Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPA----------QSRGAG----- 399 G LR +A + R G +T+ R + A R D GP +SR AG Sbjct: 133 G-LRISAEETVAR--GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189 Query: 400 -RGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRG 458 R P + P EGP++S S E S PS A++ PSA G G Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHS-------------TTEPSPAARRRPSA---GGG 233 Query: 459 NIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLL 518 SR L S +P S P+ + G P++ A P K L+ R P + Sbjct: 234 LQRPASRSLSSSATPLSS----PARSGPSARGTPRAPAH--PSQPKPKGLQALRPPQVTP 287 Query: 519 DRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS--ESTLYPMPVL-VPL 575 R + A A L P P+ G + RP P + + +TL P P L PL Sbjct: 288 PRKDAAPAL--GPLSSSPLATPS-PSGTKARPV---PPPDNAATPLPATLPPSPPLATPL 341 Query: 576 AVAP 579 +AP Sbjct: 342 PLAP 345 Score = 31.6 bits (70), Expect = 2.9 Identities = 95/382 (24%), Positives = 126/382 (32%), Gaps = 55/382 (14%) Query: 271 EVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNT--IQTGPVLEAGP- 327 E P P+P A SPL ETP S P+ P L + +Q P P Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPS----SIATPPPQAPPALASPPLQGLPSPPLSPL 614 Query: 328 ARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGRE 387 A L L + P S PL A+PSPQ + L+ AP Sbjct: 615 ATPPPQAPPXLALPPLQAPP--SPPASPPLSPLATPSPQAPNALAVH-----LLQAPFSP 667 Query: 388 DEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQ 447 P Q+ + P P + P + P S V SP + Sbjct: 668 PPSPPVQAPFSPPASP----------PVSPSATPPSQAPP--SLAAPPLQVPPSPPASPP 715 Query: 448 QTPSAQDYGRGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKV 507 +PSA + + L PSP + PS ++ PP A ++ P Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV-PPLLAAPPLQVPPSPP- 773 Query: 508 LRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRS-CSESTL 566 A P+ L +P AP P+L P LQ P+ PG++ S S Sbjct: 774 ---ASLPMSPLAKP--PPQAP-PALATPP---------LQALPSPPASFPGQAPFSPSAS 818 Query: 567 YPMPVLVPLAVAPQESHRTSAQALFPF----EASLLTSVARRKHRRWQSTVEISARARLA 622 PM PLA P ++ A L AS RR T R LA Sbjct: 819 LPMS---PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 875 Query: 623 SCPESNLGPPRPVARRAGGPLA 644 P GPP P +R L+ Sbjct: 876 LAP----GPPPPPSRSPSSTLS 893 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 45.8 bits (107), Expect = 2e-04 Identities = 76/339 (22%), Positives = 122/339 (35%), Gaps = 49/339 (14%) Query: 264 LVSQGGREVYPYPSPLH-AVALQSPLFVLTKETPQRGGPSFPRE-SPRGPAGLN------ 315 LV+ G + P P P +Q+P FV P PS P +P PA Sbjct: 217 LVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA 276 Query: 316 --TIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQRQGGWST 373 T+ P AGP A + PA G G A +P+P G Sbjct: 277 PATLARPPGHPAGPPTAAPAVP---------PPAAAQNG--GSAGAAPAPAPAAGGPAGV 325 Query: 374 DG----GGRLLVFAPG-------REDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPE 422 G G APG R + P ++ GP + GP G+LP Sbjct: 326 SGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPS 385 Query: 423 EGSKPSNSCVLRETMVQASPSSKAQ---QTPSAQDYGRGNIISPSRMLDKSPSPASGHFA 479 + P + + + + + Q +TP+A G ++P+ + + P P Sbjct: 386 PAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQ---- 441 Query: 480 HPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHW 539 +P+ + ++ P + RS ++L +Q L + AHA PQ ++ PA Sbjct: 442 NPTNIQNFQLPP----GMVLVRSENGQLLMIPQQALAQMQAQ--AHAQPQTTMAPRPA-T 494 Query: 540 PTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVA 578 PT +Q +APG + P ++ ++ A Sbjct: 495 PTSAPPVQISTV---QAPGTPIIARQVTPTTIIKQVSQA 530 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 45.8 bits (107), Expect = 2e-04 Identities = 75/297 (25%), Positives = 102/297 (34%), Gaps = 53/297 (17%) Query: 185 PAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGL 244 PA T+ A+ PG+V+ QP GT P G + TG +K S++ Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA-KPPAQQTGSEKPSSEQPGPKA 390 Query: 245 LCQGVDI---PLHVPDPKYRQDLVSQGGREVYPYPSPL-HAVALQSPLFVL--TKETPQR 298 L Q + P P P + Q G P PL LQSP TK Q+ Sbjct: 391 LAQPPGVGKTPAQQPGPA--KPPTQQVGT-----PKPLAQQPGLQSPAKAPGPTKTPVQQ 443 Query: 299 GGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLR 358 GP GP + QTGP PAK + GP Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG---------------PAKPPPQQPGP-- 486 Query: 359 HAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSG 418 A P PQ+ G P+Q G+ + PQQ G PQQ G Sbjct: 487 --AKPPPQQPGSAKP------------------PSQQPGSTKPPPQQPGPAK-PSPQQPG 525 Query: 419 SLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPAS 475 S +P ++ + A PS++ P +Q G G + P + + P S Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT-GSGKPLQPPTVSPSAKQPPS 581 Score = 30.0 bits (66), Expect = 8.5 Identities = 71/321 (22%), Positives = 109/321 (33%), Gaps = 62/321 (19%) Query: 153 PSLGSLLPVAQAHKARPSMGDWRPRSVDETT------VPAWRPQATEEGARPPGSVEDAG 206 PS PVA +P M V ++ +P+ + Q+ E P D+ Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800 Query: 207 QPWGTFWPRPVSTGDLD-RALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLV 265 +P +F P D +A+P + ++D++++ P P Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIP------RPASDSKIISH-----------PGPSSE---- 839 Query: 266 SQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTI-QTGPVLE 324 S+G ++V P + P TK +P+ P+ SP P T QT P + Sbjct: 840 SKGQKQVDPVQKK------EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQ 893 Query: 325 AGPARARAYIDRLLHLWG-----RETPAKGSEGEQGPL-RHAASPSPQRQGGWSTDGGGR 378 P L+L + P E G L AS Q ST G Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG--- 950 Query: 379 LLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKP----SNSCVLR 434 PG + GP G P +Q P + P G G P + V + Sbjct: 951 ----QPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKK 998 Query: 435 ETMVQASP--SSKAQQTPSAQ 453 ET A+ KA+Q P+ + Sbjct: 999 ETKAPAAEKLEPKAEQAPTVK 1019 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 45.8 bits (107), Expect = 2e-04 Identities = 75/297 (25%), Positives = 102/297 (34%), Gaps = 53/297 (17%) Query: 185 PAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGL 244 PA T+ A+ PG+V+ QP GT P G + TG +K S++ Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA-KPPAQQTGSEKPSSEQPGPKA 390 Query: 245 LCQGVDI---PLHVPDPKYRQDLVSQGGREVYPYPSPL-HAVALQSPLFVL--TKETPQR 298 L Q + P P P + Q G P PL LQSP TK Q+ Sbjct: 391 LAQPPGVGKTPAQQPGPA--KPPTQQVGT-----PKPLAQQPGLQSPAKAPGPTKTPVQQ 443 Query: 299 GGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLR 358 GP GP + QTGP PAK + GP Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG---------------PAKPPPQQPGP-- 486 Query: 359 HAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSG 418 A P PQ+ G P+Q G+ + PQQ G PQQ G Sbjct: 487 --AKPPPQQPGSAKP------------------PSQQPGSTKPPPQQPGPAK-PSPQQPG 525 Query: 419 SLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPAS 475 S +P ++ + A PS++ P +Q G G + P + + P S Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT-GSGKPLQPPTVSPSAKQPPS 581 Score = 30.0 bits (66), Expect = 8.5 Identities = 71/321 (22%), Positives = 109/321 (33%), Gaps = 62/321 (19%) Query: 153 PSLGSLLPVAQAHKARPSMGDWRPRSVDETT------VPAWRPQATEEGARPPGSVEDAG 206 PS PVA +P M V ++ +P+ + Q+ E P D+ Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800 Query: 207 QPWGTFWPRPVSTGDLD-RALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLV 265 +P +F P D +A+P + ++D++++ P P Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIP------RPASDSKIISH-----------PGPSSE---- 839 Query: 266 SQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTI-QTGPVLE 324 S+G ++V P + P TK +P+ P+ SP P T QT P + Sbjct: 840 SKGQKQVDPVQKK------EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQ 893 Query: 325 AGPARARAYIDRLLHLWG-----RETPAKGSEGEQGPL-RHAASPSPQRQGGWSTDGGGR 378 P L+L + P E G L AS Q ST G Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG--- 950 Query: 379 LLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKP----SNSCVLR 434 PG + GP G P +Q P + P G G P + V + Sbjct: 951 ----QPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKK 998 Query: 435 ETMVQASP--SSKAQQTPSAQ 453 ET A+ KA+Q P+ + Sbjct: 999 ETKAPAAEKLEPKAEQAPTVK 1019 >gi|237757326 synaptojanin 1 isoform d [Homo sapiens] Length = 1526 Score = 45.4 bits (106), Expect = 2e-04 Identities = 77/339 (22%), Positives = 118/339 (34%), Gaps = 32/339 (9%) Query: 412 EGPQQSGSLPEEGSKPSNSCVLRETM---VQASPSSKAQQTPSAQDYGRGNIISPSRMLD 468 E + + EG S + E + +Q S SS +PS+ SP + Sbjct: 996 EDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPR-----TSPCQSPT 1050 Query: 469 KSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAP 528 S P PS A S GPP +++ I P + + L RP Sbjct: 1051 ISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVA 1110 Query: 529 QPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQ 588 P+ P P G Q P PG + + +P + APQ R SA Sbjct: 1111 PPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAG 1170 Query: 589 ALFPFEASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRP 648 L P S + + + + + + + A P+S+L PP + P+A P Sbjct: 1171 RLTPESQSKTSETS-----KGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMP 1225 Query: 649 -SLVRQDAYTRSDSEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGG 707 S + + T P S+ P S P+ SD G RES + Sbjct: 1226 QSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISD------GKRESPLKIDPFE 1279 Query: 708 AQSRDCDLALGYVAAGHAELAWTQEAPVSSGPLLSPVPK 746 DL+ +A A+L+ V + P+ +P PK Sbjct: 1280 ------DLSFNLLAVSKAQLS------VQTSPVPTPDPK 1306 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 43.9 bits (102), Expect = 6e-04 Identities = 60/216 (27%), Positives = 78/216 (36%), Gaps = 39/216 (18%) Query: 296 PQRGGPSFP-RESPRG---------PAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRET 345 PQR GP R P+G PAG Q P + P + + GR++ Sbjct: 474 PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533 Query: 346 -PAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQ 404 P G G R ASPSPQRQ G + V P P ++ GA GG Q Sbjct: 534 RPVAGGPGAPPAARPPASPSPQRQAG-PPQATRQTSVSGP------APPKASGAPPGGQQ 586 Query: 405 QQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPS 464 +QG P + P +G P+ + + P + Q PS G G P Sbjct: 587 RQG-PPQKPPGPAG--------PTRQASQAGPVPRTGPPTTQQPRPS----GPGPAGRPK 633 Query: 465 RMLDKSPS--------PASGHFAHPSFAASLKMGPP 492 L + PS A+G HP AS P Sbjct: 634 PQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669 Score = 37.4 bits (85), Expect = 0.053 Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 40/230 (17%) Query: 356 PLRHAASPSPQRQGGWSTDGGGRL-LVFAPGREDEGGPAQSRGAGRGGPQQQGYMP-LEG 413 P + SP R T G L L ++ G PAQ R +GGP Q G P +G Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478 Query: 414 PQQSGSLPEEGSK------PSNSCVLRETMVQASPSSKAQQ-----TPSAQDYGRGNIIS 462 P P +G + P L + + SP+S QQ P Q GR Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRL--PSPTSAPQQPASQAAPPTQGQGR----- 531 Query: 463 PSRMLDKSPS--PASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDR 520 SR + P PA+ A PS + GPP++ + P Sbjct: 532 QSRPVAGGPGAPPAARPPASPS--PQRQAGPPQATRQTSVSGPAP--------------- 574 Query: 521 PEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMP 570 P+ + A P P P G G R+ + A P R+ +T P P Sbjct: 575 PKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVP-RTGPPTTQQPRP 623 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 42.4 bits (98), Expect = 0.002 Identities = 59/214 (27%), Positives = 78/214 (36%), Gaps = 36/214 (16%) Query: 296 PQRGGPSFP-RESPRG---------PAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRET 345 PQR GP R P+G PAG Q P + P + + GR++ Sbjct: 474 PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533 Query: 346 -PAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQ 404 P G G R ASPSPQRQ G + V P P ++ GA GG Q Sbjct: 534 RPVAGGPGAPPAARPPASPSPQRQAG-PPQATRQTSVSGP------APPKASGAPPGGQQ 586 Query: 405 QQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPS 464 +QG P + P +G P+ + + P + Q PS G G P Sbjct: 587 RQG-PPQKPPGPAG--------PTRQASQAGPVPRTGPPTTQQPRPS----GPGPAGRPK 633 Query: 465 RMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEK 498 L + PS P A + GPP + K Sbjct: 634 PQLAQKPSQDV-----PPPATAAAGGPPHPQLNK 662 Score = 37.4 bits (85), Expect = 0.053 Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 40/230 (17%) Query: 356 PLRHAASPSPQRQGGWSTDGGGRL-LVFAPGREDEGGPAQSRGAGRGGPQQQGYMP-LEG 413 P + SP R T G L L ++ G PAQ R +GGP Q G P +G Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478 Query: 414 PQQSGSLPEEGSK------PSNSCVLRETMVQASPSSKAQQ-----TPSAQDYGRGNIIS 462 P P +G + P L + + SP+S QQ P Q GR Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRL--PSPTSAPQQPASQAAPPTQGQGR----- 531 Query: 463 PSRMLDKSPS--PASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDR 520 SR + P PA+ A PS + GPP++ + P Sbjct: 532 QSRPVAGGPGAPPAARPPASPS--PQRQAGPPQATRQTSVSGPAP--------------- 574 Query: 521 PEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMP 570 P+ + A P P P G G R+ + A P R+ +T P P Sbjct: 575 PKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVP-RTGPPTTQQPRP 623 >gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f [Homo sapiens] Length = 1412 Score = 41.2 bits (95), Expect = 0.004 Identities = 132/614 (21%), Positives = 200/614 (32%), Gaps = 90/614 (14%) Query: 162 AQAHKARPSMGDWRPRSVDETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGD 221 A A A +G PR T PA A G + P + + + + Sbjct: 575 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 634 Query: 222 LDRALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHA 281 + +A GLQ +A + G L QG L P V+Q E Sbjct: 635 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL----PGKTGPTVTQVKAEKQ-------- 682 Query: 282 VALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLW 341 +++ S E+ PA + T +A PA ARA Sbjct: 683 -----------EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA--------- 722 Query: 342 GRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGR- 400 AKG+ G + AA+ + QR V P R + +RG Sbjct: 723 ---PSAKGTISAPGKVVTAAAQAKQRSPS---------KVKPPVRNPQNSTVLARGPASV 770 Query: 401 ---GGPQQQGYMPLEGPQQ-SGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456 G GP++ SGS EE + ET+ Q PS K Q +A Sbjct: 771 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA----ETLAQVKPSGKTHQIRAALAPA 826 Query: 457 RGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIK---RSPMDKVLRFARQ 513 + SP + +P +G PS A + K S +E+ +P + Sbjct: 827 KE---SPRKGAAPTPPGKTG----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 879 Query: 514 PLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-----ESTLYP 568 P L+ P + A P + PA + R A A E+ RS S E + Sbjct: 880 PPLIFVDPNRSPAGPAAT----PAQ---AQAASTPRKARASESTARSSSSESEDEDVIPA 932 Query: 569 MPVLVP-----LAVAPQESHRTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLAS 623 L P + P R + +A +S S ++ + ++ AS Sbjct: 933 TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPAS 992 Query: 624 CP--ESNLGPPRPVARRAGGPLARGRPSLVRQDAY-TRSDSEPSKHSAECD-------PR 673 P ++ L A A P+AR +PS A T + P S + P+ Sbjct: 993 LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1052 Query: 674 FPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYVAAGHAELAWTQEA 733 P V T ESSD + + S D EG ++ +G + L A Sbjct: 1053 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAA 1112 Query: 734 PVSSGPLLSPVPKL 747 S +++P L Sbjct: 1113 ESSEDDVVAPSQSL 1126 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 40.8 bits (94), Expect = 0.005 Identities = 73/264 (27%), Positives = 92/264 (34%), Gaps = 46/264 (17%) Query: 193 EEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQGVDIP 252 + G P A P G P+ S GD P + G Q G P Sbjct: 893 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG--------P 944 Query: 253 LHVPDPKYRQDLVSQGGR--------EVYPYPSPLHAVALQSPLFVLTKETP---QRGGP 301 P P + L G+ + P P P V Q P T ET +RG P Sbjct: 945 KGPPGPPGKDGLPGHPGQRGETGFQGKTGP-PGPGGVVGPQGP----TGETGPIGERGHP 999 Query: 302 SFP----RESPRGPAGLNTIQTGPVLEA-----GPARARAYIDRLLHLWGRETPA-KGSE 351 P + G AG + P + GPA R + + P KG E Sbjct: 1000 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1059 Query: 352 GEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ------ 404 G QGP SP + G + G L PG + GPA +GA G GPQ Sbjct: 1060 GPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1116 Query: 405 -QQGYMPLEGPQ-QSGSLPEEGSK 426 QG + L GP +GS E+G K Sbjct: 1117 GVQGPVGLPGPAGPAGSPGEDGDK 1140 Score = 35.0 bits (79), Expect = 0.26 Identities = 37/135 (27%), Positives = 52/135 (38%), Gaps = 21/135 (15%) Query: 306 ESPRGPAGLNTIQTGPVLEAGPA-----RARAYIDRLLHLWGRETPA--------KGSEG 352 + P GP G + GP + GP+ + + + L GR+ P G+ G Sbjct: 822 DGPEGPKG----RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 877 Query: 353 EQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLE 412 E+G A P P+ Q G + G R A G + GP + G G G P G + Sbjct: 878 EKGARGVAGKPGPRGQRGPTGPRGSR---GARGPTGKPGPKGTSG-GDGPPGPPGERGPQ 933 Query: 413 GPQQSGSLPEEGSKP 427 GPQ P P Sbjct: 934 GPQGPVGFPGPKGPP 948 Score = 33.5 bits (75), Expect = 0.77 Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 6/73 (8%) Query: 4 PGGPPGSAGWDRRR-----LGARLRAAFAGLQELQGLRATQQERVRGALA-LQPPPAPAA 57 P GPPG G D R +G R AG + L G R T + +A + PP P Sbjct: 632 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 691 Query: 58 PCGPHGLHGPEQQ 70 GP G GP Q Sbjct: 692 NMGPQGEPGPPGQ 704 Score = 32.0 bits (71), Expect = 2.2 Identities = 45/170 (26%), Positives = 60/170 (35%), Gaps = 40/170 (23%) Query: 256 PDPKYRQDLVSQGGRE-VYPYPSPLHAVALQSPLFVLTKETPQRG--------GPSFPRE 306 P P+ +Q + Q G E +P P + LQ L ++G GP P Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG----LPGPPGEKGENGDVGPMGPPGP-P 1236 Query: 307 SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQ 366 PRGP G N GP GP + + G GE+G A +P P Sbjct: 1237 GPRGPQGPNGAD-GP---QGPPGSVGSV--------------GGVGEKGEPGEAGNPGPP 1278 Query: 367 RQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGP 414 + G G R G + E GP + G +G P G GP Sbjct: 1279 GEAGVGGPKGER------GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1322 Score = 31.6 bits (70), Expect = 2.9 Identities = 36/120 (30%), Positives = 43/120 (35%), Gaps = 9/120 (7%) Query: 300 GPSFPR--ESPRGPAGLNTIQTGPVLEAG---PARARAYIDRLLHLWGRETPAKGSEGEQ 354 GP PR + P GP G + P + G P A DR KG GE+ Sbjct: 571 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 630 Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGP 414 GP P G + G R L PG G RG G P Q G ++GP Sbjct: 631 GPQGPPGPPGDDGMRGEDGEIGPRGL---PGEAGPRGLLGPRGT-PGAPGQPGMAGVDGP 686 Score = 30.0 bits (66), Expect = 8.5 Identities = 50/201 (24%), Positives = 67/201 (33%), Gaps = 32/201 (15%) Query: 300 GPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRH 359 G P+ +P GP G GP E GPA + G +GE G Sbjct: 1312 GDDGPKGNP-GPVGFPG-DPGPPGEPGPAG--------------QDGVGGDKGEDGDPGQ 1355 Query: 360 AASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQQS 417 P P + G G R A G E G ++G G P + G + +GP + Sbjct: 1356 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP--A 1413 Query: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477 G EG + V Q P + Q P G + P K + G Sbjct: 1414 GKPGPEGLRGIPGPVGE----QGLPGAAGQDGPP------GPMGPPGLPGLKGDPGSKGE 1463 Query: 478 FAHPSFAASLKMGPPKSKAEK 498 HP + GPP + EK Sbjct: 1464 KGHPGLIGLI--GPPGEQGEK 1482 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 40.8 bits (94), Expect = 0.005 Identities = 73/264 (27%), Positives = 92/264 (34%), Gaps = 46/264 (17%) Query: 193 EEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQGVDIP 252 + G P A P G P+ S GD P + G Q G P Sbjct: 842 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG--------P 893 Query: 253 LHVPDPKYRQDLVSQGGR--------EVYPYPSPLHAVALQSPLFVLTKETP---QRGGP 301 P P + L G+ + P P P V Q P T ET +RG P Sbjct: 894 KGPPGPPGKDGLPGHPGQRGETGFQGKTGP-PGPGGVVGPQGP----TGETGPIGERGHP 948 Query: 302 SFP----RESPRGPAGLNTIQTGPVLEA-----GPARARAYIDRLLHLWGRETPA-KGSE 351 P + G AG + P + GPA R + + P KG E Sbjct: 949 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1008 Query: 352 GEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ------ 404 G QGP SP + G + G L PG + GPA +GA G GPQ Sbjct: 1009 GPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1065 Query: 405 -QQGYMPLEGPQ-QSGSLPEEGSK 426 QG + L GP +GS E+G K Sbjct: 1066 GVQGPVGLPGPAGPAGSPGEDGDK 1089 Score = 35.0 bits (79), Expect = 0.26 Identities = 37/135 (27%), Positives = 52/135 (38%), Gaps = 21/135 (15%) Query: 306 ESPRGPAGLNTIQTGPVLEAGPA-----RARAYIDRLLHLWGRETPA--------KGSEG 352 + P GP G + GP + GP+ + + + L GR+ P G+ G Sbjct: 771 DGPEGPKG----RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826 Query: 353 EQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLE 412 E+G A P P+ Q G + G R A G + GP + G G G P G + Sbjct: 827 EKGARGVAGKPGPRGQRGPTGPRGSR---GARGPTGKPGPKGTSG-GDGPPGPPGERGPQ 882 Query: 413 GPQQSGSLPEEGSKP 427 GPQ P P Sbjct: 883 GPQGPVGFPGPKGPP 897 Score = 33.5 bits (75), Expect = 0.77 Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 6/73 (8%) Query: 4 PGGPPGSAGWDRRR-----LGARLRAAFAGLQELQGLRATQQERVRGALA-LQPPPAPAA 57 P GPPG G D R +G R AG + L G R T + +A + PP P Sbjct: 581 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 640 Query: 58 PCGPHGLHGPEQQ 70 GP G GP Q Sbjct: 641 NMGPQGEPGPPGQ 653 Score = 32.0 bits (71), Expect = 2.2 Identities = 45/170 (26%), Positives = 60/170 (35%), Gaps = 40/170 (23%) Query: 256 PDPKYRQDLVSQGGRE-VYPYPSPLHAVALQSPLFVLTKETPQRG--------GPSFPRE 306 P P+ +Q + Q G E +P P + LQ L ++G GP P Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG----LPGPPGEKGENGDVGPMGPPGP-P 1185 Query: 307 SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQ 366 PRGP G N GP GP + + G GE+G A +P P Sbjct: 1186 GPRGPQGPNGAD-GP---QGPPGSVGSV--------------GGVGEKGEPGEAGNPGPP 1227 Query: 367 RQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGP 414 + G G R G + E GP + G +G P G GP Sbjct: 1228 GEAGVGGPKGER------GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1271 Score = 31.6 bits (70), Expect = 2.9 Identities = 36/120 (30%), Positives = 43/120 (35%), Gaps = 9/120 (7%) Query: 300 GPSFPR--ESPRGPAGLNTIQTGPVLEAG---PARARAYIDRLLHLWGRETPAKGSEGEQ 354 GP PR + P GP G + P + G P A DR KG GE+ Sbjct: 520 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 579 Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGP 414 GP P G + G R L PG G RG G P Q G ++GP Sbjct: 580 GPQGPPGPPGDDGMRGEDGEIGPRGL---PGEAGPRGLLGPRGT-PGAPGQPGMAGVDGP 635 Score = 30.0 bits (66), Expect = 8.5 Identities = 50/201 (24%), Positives = 67/201 (33%), Gaps = 32/201 (15%) Query: 300 GPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRH 359 G P+ +P GP G GP E GPA + G +GE G Sbjct: 1261 GDDGPKGNP-GPVGFPG-DPGPPGEPGPAG--------------QDGVGGDKGEDGDPGQ 1304 Query: 360 AASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQQS 417 P P + G G R A G E G ++G G P + G + +GP + Sbjct: 1305 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP--A 1362 Query: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477 G EG + V Q P + Q P G + P K + G Sbjct: 1363 GKPGPEGLRGIPGPVGE----QGLPGAAGQDGPP------GPMGPPGLPGLKGDPGSKGE 1412 Query: 478 FAHPSFAASLKMGPPKSKAEK 498 HP + GPP + EK Sbjct: 1413 KGHPGLIGLI--GPPGEQGEK 1431 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 40.8 bits (94), Expect = 0.005 Identities = 73/264 (27%), Positives = 92/264 (34%), Gaps = 46/264 (17%) Query: 193 EEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQGVDIP 252 + G P A P G P+ S GD P + G Q G P Sbjct: 881 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG--------P 932 Query: 253 LHVPDPKYRQDLVSQGGR--------EVYPYPSPLHAVALQSPLFVLTKETP---QRGGP 301 P P + L G+ + P P P V Q P T ET +RG P Sbjct: 933 KGPPGPPGKDGLPGHPGQRGETGFQGKTGP-PGPGGVVGPQGP----TGETGPIGERGHP 987 Query: 302 SFP----RESPRGPAGLNTIQTGPVLEA-----GPARARAYIDRLLHLWGRETPA-KGSE 351 P + G AG + P + GPA R + + P KG E Sbjct: 988 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1047 Query: 352 GEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ------ 404 G QGP SP + G + G L PG + GPA +GA G GPQ Sbjct: 1048 GPQGPPGPVGSPGERGSAGTAGPIG---LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1104 Query: 405 -QQGYMPLEGPQ-QSGSLPEEGSK 426 QG + L GP +GS E+G K Sbjct: 1105 GVQGPVGLPGPAGPAGSPGEDGDK 1128 Score = 35.0 bits (79), Expect = 0.26 Identities = 37/135 (27%), Positives = 52/135 (38%), Gaps = 21/135 (15%) Query: 306 ESPRGPAGLNTIQTGPVLEAGPA-----RARAYIDRLLHLWGRETPA--------KGSEG 352 + P GP G + GP + GP+ + + + L GR+ P G+ G Sbjct: 810 DGPEGPKG----RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865 Query: 353 EQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLE 412 E+G A P P+ Q G + G R A G + GP + G G G P G + Sbjct: 866 EKGARGVAGKPGPRGQRGPTGPRGSR---GARGPTGKPGPKGTSG-GDGPPGPPGERGPQ 921 Query: 413 GPQQSGSLPEEGSKP 427 GPQ P P Sbjct: 922 GPQGPVGFPGPKGPP 936 Score = 33.5 bits (75), Expect = 0.77 Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 6/73 (8%) Query: 4 PGGPPGSAGWDRRR-----LGARLRAAFAGLQELQGLRATQQERVRGALA-LQPPPAPAA 57 P GPPG G D R +G R AG + L G R T + +A + PP P Sbjct: 620 PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 679 Query: 58 PCGPHGLHGPEQQ 70 GP G GP Q Sbjct: 680 NMGPQGEPGPPGQ 692 Score = 32.0 bits (71), Expect = 2.2 Identities = 45/170 (26%), Positives = 60/170 (35%), Gaps = 40/170 (23%) Query: 256 PDPKYRQDLVSQGGRE-VYPYPSPLHAVALQSPLFVLTKETPQRG--------GPSFPRE 306 P P+ +Q + Q G E +P P + LQ L ++G GP P Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG----LPGPPGEKGENGDVGPMGPPGP-P 1224 Query: 307 SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQ 366 PRGP G N GP GP + + G GE+G A +P P Sbjct: 1225 GPRGPQGPNGAD-GP---QGPPGSVGSV--------------GGVGEKGEPGEAGNPGPP 1266 Query: 367 RQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGP 414 + G G R G + E GP + G +G P G GP Sbjct: 1267 GEAGVGGPKGER------GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1310 Score = 31.6 bits (70), Expect = 2.9 Identities = 36/120 (30%), Positives = 43/120 (35%), Gaps = 9/120 (7%) Query: 300 GPSFPR--ESPRGPAGLNTIQTGPVLEAG---PARARAYIDRLLHLWGRETPAKGSEGEQ 354 GP PR + P GP G + P + G P A DR KG GE+ Sbjct: 559 GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 618 Query: 355 GPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGP 414 GP P G + G R L PG G RG G P Q G ++GP Sbjct: 619 GPQGPPGPPGDDGMRGEDGEIGPRGL---PGEAGPRGLLGPRGT-PGAPGQPGMAGVDGP 674 Score = 30.0 bits (66), Expect = 8.5 Identities = 50/201 (24%), Positives = 67/201 (33%), Gaps = 32/201 (15%) Query: 300 GPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRH 359 G P+ +P GP G GP E GPA + G +GE G Sbjct: 1300 GDDGPKGNP-GPVGFPG-DPGPPGEPGPAG--------------QDGVGGDKGEDGDPGQ 1343 Query: 360 AASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQQS 417 P P + G G R A G E G ++G G P + G + +GP + Sbjct: 1344 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP--A 1401 Query: 418 GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGH 477 G EG + V Q P + Q P G + P K + G Sbjct: 1402 GKPGPEGLRGIPGPVGE----QGLPGAAGQDGPP------GPMGPPGLPGLKGDPGSKGE 1451 Query: 478 FAHPSFAASLKMGPPKSKAEK 498 HP + GPP + EK Sbjct: 1452 KGHPGLIGLI--GPPGEQGEK 1470 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 40.8 bits (94), Expect = 0.005 Identities = 43/134 (32%), Positives = 49/134 (36%), Gaps = 20/134 (14%) Query: 299 GGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLR 358 G P FP PRGP G TGP+ G E G +GEQGP Sbjct: 429 GAPGFP--GPRGPPGPQGA-TGPLGPKGQTG--------------EPGIAGFKGEQGPKG 471 Query: 359 HAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA--GRGGPQQQGYM-PLEGPQ 415 PQ G + + G R PG GP RGA RG P Q G P P Sbjct: 472 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531 Query: 416 QSGSLPEEGSKPSN 429 + G G K +N Sbjct: 532 ERGPSGLAGPKGAN 545 Score = 32.3 bits (72), Expect = 1.7 Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 26/111 (23%) Query: 298 RGGPSFPRES-PRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGP 356 RG P E+ P GPAG AGP A + AKG +GE G Sbjct: 818 RGAPGERGETGPPGPAGF----------AGPPGADG-----------QPGAKGEQGEAGQ 856 Query: 357 LRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG----AGRGGP 403 A +P PQ G G + G GP + G AGR GP Sbjct: 857 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGP 907 Score = 32.3 bits (72), Expect = 1.7 Identities = 38/129 (29%), Positives = 48/129 (37%), Gaps = 33/129 (25%) Query: 299 GGPSFPRESPR-GPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357 G FP + R GP G N GP GP+ G++ P KG+ G+ GP Sbjct: 894 GATGFPGAAGRVGPPGSNG-NPGPPGPPGPS-------------GKDGP-KGARGDSGPP 938 Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ----QQGYMPLE 412 A P Q G PG + E G GA G GPQ Q+G + L Sbjct: 939 GRAGEPGLQGPAG------------PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986 Query: 413 GPQQSGSLP 421 G + P Sbjct: 987 GQRGERGFP 995 Score = 32.0 bits (71), Expect = 2.2 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 4 PGGPPGSAGWDRRRLGARLRAAFAGL--QELQGLRATQQERVRGALALQPPPAPAAPCGP 61 P GPPG G LG A AG ++ G + + G + + PP PA GP Sbjct: 166 PPGPPGPPG-----LGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 220 Query: 62 HGLHG 66 G G Sbjct: 221 QGFQG 225 Score = 31.6 bits (70), Expect = 2.9 Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 28/104 (26%) Query: 308 PRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQR 367 P GP GL G GPA A A+G++G+ GP A P P Sbjct: 322 PMGPRGL----PGERGRTGPAGAAG--------------ARGNDGQPGP---AGPPGPVG 360 Query: 368 QGGWSTDGGGRLLVFAPGREDEGGPAQSRG-AGRGGPQQQGYMP 410 G G APG + E GP +RG G GP+ + P Sbjct: 361 PAGGPGFPG------APGAKGEAGPTGARGPEGAQGPRGEPGTP 398 Score = 31.2 bits (69), Expect = 3.8 Identities = 37/120 (30%), Positives = 44/120 (36%), Gaps = 22/120 (18%) Query: 300 GPSFPRESPRGPAGLNTIQTGPVL--EAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357 GP+ P P GPAG P EAGP T A+G EG QGP Sbjct: 351 GPAGP-PGPVGPAGGPGFPGAPGAKGEAGP-----------------TGARGPEGAQGPR 392 Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQ 415 +P G S + G + A G G A + G RG P QG GP+ Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 452 Score = 30.4 bits (67), Expect = 6.5 Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 17/80 (21%) Query: 4 PGGPPGSAGWDRRRLGARLR------AAFAGLQELQGLRATQQERV----------RGAL 47 P GP G G DR GA+ A G+Q QG R + E RG Sbjct: 1078 PAGPTGKQG-DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1136 Query: 48 ALQPPPAPAAPCGPHGLHGP 67 LQ P P P G G GP Sbjct: 1137 GLQGLPGPPGPSGDQGASGP 1156 Score = 30.0 bits (66), Expect = 8.5 Identities = 42/158 (26%), Positives = 53/158 (33%), Gaps = 34/158 (21%) Query: 297 QRGGPSFPRE--SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQ 354 Q+G P ++ P+GP G GP E GP R G P +G +GE Sbjct: 105 QKGEPGDIKDIVGPKGPPG----PQGPAGEQGPRGDRGDKGEK----GAPGP-RGRDGEP 155 Query: 355 GPLRHAASPSP---------------QRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG-A 398 G + P P Q GG+ GG L G GP G A Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215 Query: 399 GRGGPQ-------QQGYMPLEGPQQSGSLPEEGSKPSN 429 G GPQ + G + GP P KP + Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 253 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 40.8 bits (94), Expect = 0.005 Identities = 43/134 (32%), Positives = 49/134 (36%), Gaps = 20/134 (14%) Query: 299 GGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLR 358 G P FP PRGP G TGP+ G E G +GEQGP Sbjct: 360 GAPGFP--GPRGPPGPQGA-TGPLGPKGQTG--------------EPGIAGFKGEQGPKG 402 Query: 359 HAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA--GRGGPQQQGYM-PLEGPQ 415 PQ G + + G R PG GP RGA RG P Q G P P Sbjct: 403 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 462 Query: 416 QSGSLPEEGSKPSN 429 + G G K +N Sbjct: 463 ERGPSGLAGPKGAN 476 Score = 32.3 bits (72), Expect = 1.7 Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 26/111 (23%) Query: 298 RGGPSFPRES-PRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGP 356 RG P E+ P GPAG AGP A + AKG +GE G Sbjct: 749 RGAPGERGETGPPGPAGF----------AGPPGADG-----------QPGAKGEQGEAGQ 787 Query: 357 LRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG----AGRGGP 403 A +P PQ G G + G GP + G AGR GP Sbjct: 788 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGP 838 Score = 32.3 bits (72), Expect = 1.7 Identities = 38/129 (29%), Positives = 48/129 (37%), Gaps = 33/129 (25%) Query: 299 GGPSFPRESPR-GPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357 G FP + R GP G N GP GP+ G++ P KG+ G+ GP Sbjct: 825 GATGFPGAAGRVGPPGSNG-NPGPPGPPGPS-------------GKDGP-KGARGDSGPP 869 Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA-GRGGPQ----QQGYMPLE 412 A P Q G PG + E G GA G GPQ Q+G + L Sbjct: 870 GRAGEPGLQGPAG------------PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917 Query: 413 GPQQSGSLP 421 G + P Sbjct: 918 GQRGERGFP 926 Score = 32.0 bits (71), Expect = 2.2 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 4 PGGPPGSAGWDRRRLGARLRAAFAGL--QELQGLRATQQERVRGALALQPPPAPAAPCGP 61 P GPPG G LG A AG ++ G + + G + + PP PA GP Sbjct: 97 PPGPPGPPG-----LGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGP 151 Query: 62 HGLHG 66 G G Sbjct: 152 QGFQG 156 Score = 31.6 bits (70), Expect = 2.9 Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 28/104 (26%) Query: 308 PRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQR 367 P GP GL G GPA A A+G++G+ GP A P P Sbjct: 253 PMGPRGL----PGERGRTGPAGAAG--------------ARGNDGQPGP---AGPPGPVG 291 Query: 368 QGGWSTDGGGRLLVFAPGREDEGGPAQSRG-AGRGGPQQQGYMP 410 G G APG + E GP +RG G GP+ + P Sbjct: 292 PAGGPGFPG------APGAKGEAGPTGARGPEGAQGPRGEPGTP 329 Score = 31.2 bits (69), Expect = 3.8 Identities = 37/120 (30%), Positives = 44/120 (36%), Gaps = 22/120 (18%) Query: 300 GPSFPRESPRGPAGLNTIQTGPVL--EAGPARARAYIDRLLHLWGRETPAKGSEGEQGPL 357 GP+ P P GPAG P EAGP T A+G EG QGP Sbjct: 282 GPAGP-PGPVGPAGGPGFPGAPGAKGEAGP-----------------TGARGPEGAQGPR 323 Query: 358 RHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG--AGRGGPQQQGYMPLEGPQ 415 +P G S + G + A G G A + G RG P QG GP+ Sbjct: 324 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 383 Score = 30.4 bits (67), Expect = 6.5 Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 17/80 (21%) Query: 4 PGGPPGSAGWDRRRLGARLR------AAFAGLQELQGLRATQQERV----------RGAL 47 P GP G G DR GA+ A G+Q QG R + E RG Sbjct: 1009 PAGPTGKQG-DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1067 Query: 48 ALQPPPAPAAPCGPHGLHGP 67 LQ P P P G G GP Sbjct: 1068 GLQGLPGPPGPSGDQGASGP 1087 Score = 30.0 bits (66), Expect = 8.5 Identities = 42/158 (26%), Positives = 53/158 (33%), Gaps = 34/158 (21%) Query: 297 QRGGPSFPRE--SPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQ 354 Q+G P ++ P+GP G GP E GP R G P +G +GE Sbjct: 36 QKGEPGDIKDIVGPKGPPG----PQGPAGEQGPRGDRGDKGEK----GAPGP-RGRDGEP 86 Query: 355 GPLRHAASPSP---------------QRQGGWSTDGGGRLLVFAPGREDEGGPAQSRG-A 398 G + P P Q GG+ GG L G GP G A Sbjct: 87 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146 Query: 399 GRGGPQ-------QQGYMPLEGPQQSGSLPEEGSKPSN 429 G GPQ + G + GP P KP + Sbjct: 147 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184 >gi|188536004 zinc finger protein 469 [Homo sapiens] Length = 3925 Score = 40.8 bits (94), Expect = 0.005 Identities = 73/320 (22%), Positives = 102/320 (31%), Gaps = 29/320 (9%) Query: 349 GSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGY 408 GS+G G P + S+ GG L G D G G + G Sbjct: 516 GSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGT 575 Query: 409 MPLEGPQQSGSLPEEGSKPSNSC-VLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRML 467 L P+ G+ P E PS + T SP S + PS+++ + PS Sbjct: 576 PSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFF 635 Query: 468 --DKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAH 525 P F P SL P + E K P A L+ H Sbjct: 636 HPPTHPQETGSPFPSPEPPHSL---PTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPH 692 Query: 526 AAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGR--SCSESTLYPMPVLVPLAVAPQESH 583 P+ GRGGLQ P P S S ++L + VL+ + Sbjct: 693 EGPE-----------VGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRNYS 741 Query: 584 RTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPL 643 +A LL + A+ H+R L S P + PR A G L Sbjct: 742 SLAAFLAHRQFCGLLLARAKDGHQR------SPGPPGLPSPPAA----PRVPADAHAGLL 791 Query: 644 ARGRPSLVRQDAYTRSDSEP 663 + + L+ DA +P Sbjct: 792 SHAKTFLLAGDAQAEGKDDP 811 Score = 36.2 bits (82), Expect = 0.12 Identities = 54/228 (23%), Positives = 76/228 (33%), Gaps = 31/228 (13%) Query: 284 LQSPLFVLTKETPQRGGP--SFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLW 341 LQ V + GGP +F + S PAG + + P++A + Sbjct: 3616 LQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAV 3675 Query: 342 GRETP---AKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGA 398 G P A+G+E P A P P QG G P Sbjct: 3676 GSLAPGELARGTENGMKPATPKAKPGPSSQGS-------------------GSPRPGTKT 3716 Query: 399 GRGGPQQQGYMPLEGPQQS--GSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456 G GG Q Q P G QS + P + S PS S +A S + A + G Sbjct: 3717 G-GGSQPQ---PASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQG 3772 Query: 457 RGNIISPSRMLDKSPSPASGHFAHPSFAASL-KMGPPKSKAEKIKRSP 503 + P + S G P+ + S+ G S +K R+P Sbjct: 3773 PHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTP 3820 Score = 32.7 bits (73), Expect = 1.3 Identities = 123/581 (21%), Positives = 187/581 (32%), Gaps = 109/581 (18%) Query: 131 MSDGGSCSLSTSCASVCSDHISPSLGSLL---PVAQAHKARPSMGDWRPRSVD------- 180 + D +C+ S + A+ H+ SLG L P+ +A+ +G P S Sbjct: 2079 VGDLAACAPSPTSAA----HMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGP 2134 Query: 181 ---ETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASA 237 PAW P +G + + D G P ++T D P + Sbjct: 2135 QQLLACSPAWAPLEEADGVQ---ATTDTGAEDSPVAPPSLTTSPCD---PKEA------- 2181 Query: 238 DAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQ 297 L G L QG PL P +P P + AV + +TP+ Sbjct: 2182 ---LAGCLLQGEGSPLEDPSS--------------WP-PGSVSAVTCTH-----SGDTPK 2218 Query: 298 RGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRL-LHLWGRETPAKGSEGEQGP 356 P +S + + P P A A + + G + G E + G Sbjct: 2219 DSTLRIPEDSRK-----EKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAG- 2272 Query: 357 LRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQ 416 R P PQ +G R+ P P+ + G Q +P E P Sbjct: 2273 -RGLPGPDPQSRGAPPHTNPDRM----PRGHSSYSPSNTARLGHREGQAVTAVPTEPPTL 2327 Query: 417 SGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASG 476 G+ P+ S +C+ E SSK + P + GR R+ S G Sbjct: 2328 QGAGPD-----SPACLEGEM----GTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLG 2378 Query: 477 HFAHPSFAAS-LKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWD 535 PS AS + P+S ++P L P L R G P + + Sbjct: 2379 RTTAPSSTASDFQSDSPQSHRNASHQTPQGDPL----GPQDLKQRSRGYKKKPAST---E 2431 Query: 536 PAHW----PTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALF 591 W P G + A PG S ++ + P AP E + A Sbjct: 2432 NGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHR-----PHPGAPAEPSPAALPAQQ 2486 Query: 592 PFE--ASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPS 649 P E A ++ HR +S + R P + G P V + P A+G Sbjct: 2487 PLEPLAQKCQPPRKKSHR-------VSGKER----PNHSRGDPSHVTQ---PPPAQGSKE 2532 Query: 650 LVRQDAYTRSDS--EPSKHSAECDPRFPSVIPETSEGESSD 688 ++R S PS E D + P+ P + + Sbjct: 2533 VLRAPGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDE 2573 >gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens] Length = 476 Score = 40.8 bits (94), Expect = 0.005 Identities = 67/242 (27%), Positives = 87/242 (35%), Gaps = 43/242 (17%) Query: 189 PQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLD--RALPADTG-LQKASADAELLGLL 245 P +E+ + PG ED G W S G L + LPAD G L+ S DAE+ L Sbjct: 48 PLPSEQCYQAPGGPEDRGPAWVG------SHGVLQHTQGLPADRGGLRPGSLDAEIDLLS 101 Query: 246 CQGVDIPLHVPDPKYRQDLVSQGGREVY-PYPSPLHAVALQSPLFVLTKETPQRGGPSFP 304 ++ R D R+ Y P P P + P GGP+ Sbjct: 102 STLAELNGGRGHASRRPD------RQAYEPPPPPAYRTGSLKPNPASPLPASPYGGPT-- 153 Query: 305 RESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPS 364 PA T T AGPA + + G P +G+ GPL P Sbjct: 154 ------PASYTTAST----PAGPAFP-VQVKVAQPVRGCGPPRRGASQASGPLPGPHFPL 202 Query: 365 PQRQGGWSTDGGGRLLVFAPG---REDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLP 421 P GR V+ PG + + G A+ AG GP +G GPQ S P Sbjct: 203 P-----------GRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHGPQVPLSQP 251 Query: 422 EE 423 E Sbjct: 252 PE 253 >gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] Length = 1336 Score = 40.8 bits (94), Expect = 0.005 Identities = 68/270 (25%), Positives = 97/270 (35%), Gaps = 53/270 (19%) Query: 189 PQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQG 248 P T+ PPG G P P + G P G+Q + L+GL +G Sbjct: 734 PPGTQGMQGPPGPRGMQGPPH----PHGIQGG------PGSQGIQGPVSQGPLMGLNPRG 783 Query: 249 VDIPLHVPDPKYRQDLVSQGGREVYPY-----PSPLHAVALQSPLFVLTKET-------P 296 + P P P+ Q QG +P P P + P + + P Sbjct: 784 MQGP---PGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP 840 Query: 297 QRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGP 356 +G P + RGP G + Q P GP + + G++ PA+G QGP Sbjct: 841 PQGSMLGPPQELRGPPGSQSQQGPPQGSLGPP-PQGGMQGPPGPQGQQNPARGPHPSQGP 899 Query: 357 L--RHAASP-------SPQRQGGWST------------DGGGRLLVFAPGREDEGGPAQS 395 + + +P +P Q G ST GR+ PG+ GP + Sbjct: 900 IPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQ----GPGPN 955 Query: 396 RGAGRGGP-QQQGYMPLEGPQQSGSLPEEG 424 +G RG P G M +QSG PE G Sbjct: 956 KGDSRGPPNHHMGPMSERRHEQSGG-PEHG 984 Score = 40.0 bits (92), Expect = 0.008 Identities = 66/281 (23%), Positives = 96/281 (34%), Gaps = 38/281 (13%) Query: 274 PYPSPLHAVALQSPLFVLTKETPQRGGPSFPR-ESPRGPAGLNTIQT--GPVLEAGPARA 330 P PLH P + + PQ PR + GP G+ GP+ GP Sbjct: 637 PQGPPLHQGG-GGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGP 695 Query: 331 RAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEG 390 + H+ +G G QG + P PQ G G + + PG Sbjct: 696 QGSSGPQGHMG-----PQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQ 750 Query: 391 GPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTP 450 GP G +GGP QG ++GP G P G P +Q P + Q P Sbjct: 751 GPPHPHGI-QGGPGSQG---IQGPVSQG--PLMGLNPRG--------MQGPPGPRENQGP 796 Query: 451 SAQDYGRGNIISPSRMLDKSPSPASGHFAH-------PSFAASLKMGPPKSK----AEKI 499 + Q G+ P M + P P G H P ++ PP+ +++ Sbjct: 797 APQGMIMGH--PPQEM--RGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQEL 852 Query: 500 KRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWP 540 + P + + Q L G P P + +PA P Sbjct: 853 RGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGP 893 >gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3 [Homo sapiens] Length = 535 Score = 40.4 bits (93), Expect = 0.006 Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%) Query: 348 KGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQG 407 +G G P R +P P+ + G+S G AP G P SRG GRGGP QQ Sbjct: 408 RGGRGAPPPPRGRGAPPPRGRAGYSQRG-------AP----LGPPRGSRG-GRGGPAQQ- 454 Query: 408 YMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456 + GS G++ N R+ P SK +QT + Q++G Sbjct: 455 ------QRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWG 497 >gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1 [Homo sapiens] Length = 636 Score = 40.4 bits (93), Expect = 0.006 Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%) Query: 348 KGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQG 407 +G G P R +P P+ + G+S G AP G P SRG GRGGP QQ Sbjct: 509 RGGRGAPPPPRGRGAPPPRGRAGYSQRG-------AP----LGPPRGSRG-GRGGPAQQ- 555 Query: 408 YMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456 + GS G++ N R+ P SK +QT + Q++G Sbjct: 556 ------QRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWG 598 >gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4 [Homo sapiens] Length = 532 Score = 40.4 bits (93), Expect = 0.006 Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%) Query: 348 KGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQG 407 +G G P R +P P+ + G+S G AP G P SRG GRGGP QQ Sbjct: 405 RGGRGAPPPPRGRGAPPPRGRAGYSQRG-------AP----LGPPRGSRG-GRGGPAQQ- 451 Query: 408 YMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456 + GS G++ N R+ P SK +QT + Q++G Sbjct: 452 ------QRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWG 494 >gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [Homo sapiens] Length = 633 Score = 40.4 bits (93), Expect = 0.006 Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 19/109 (17%) Query: 348 KGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQG 407 +G G P R +P P+ + G+S G AP G P SRG GRGGP QQ Sbjct: 506 RGGRGAPPPPRGRGAPPPRGRAGYSQRG-------AP----LGPPRGSRG-GRGGPAQQ- 552 Query: 408 YMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456 + GS G++ N R+ P SK +QT + Q++G Sbjct: 553 ------QRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWG 595 >gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d [Homo sapiens] Length = 1488 Score = 40.0 bits (92), Expect = 0.008 Identities = 129/579 (22%), Positives = 191/579 (32%), Gaps = 92/579 (15%) Query: 162 AQAHKARPSMGDWRPRSVDETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGD 221 A A A +G PR T PA A G + P + + + + Sbjct: 652 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 711 Query: 222 LDRALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHA 281 + +A GLQ +A + G L QG L P V+Q E Sbjct: 712 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL----PGKTGPTVTQVKAEKQ-------- 759 Query: 282 VALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLW 341 +++ S E+ PA + T +A PA ARA Sbjct: 760 -----------EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA--------- 799 Query: 342 GRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGR- 400 AKG+ G + AA+ + QR V P R + +RG Sbjct: 800 ---PSAKGTISAPGKVVTAAAQAKQRSPS---------KVKPPVRNPQNSTVLARGPASV 847 Query: 401 ---GGPQQQGYMPLEGPQQ-SGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456 G GP++ SGS EE + ET+ Q PS K Q +A Sbjct: 848 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA----ETLAQVKPSGKTHQIRAALAPA 903 Query: 457 RGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIK---RSPMDKVLRFARQ 513 + SP + +P +G PS A + K S +E+ +P + Sbjct: 904 KE---SPRKGAAPTPPGKTG----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 956 Query: 514 PLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-----ESTLYP 568 P L+ P + A P + PA + R A A E+ RS S E + Sbjct: 957 PPLIFVDPNRSPAGPAAT----PAQ---AQAASTPRKARASESTARSSSSESEDEDVIPA 1009 Query: 569 MPVLVP-----LAVAPQESHRTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLAS 623 L P + P R + +A +S S ++ + ++ AS Sbjct: 1010 TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPAS 1069 Query: 624 CP--ESNLGPPRPVARRAGGPLARGRPSLVRQDAY-TRSDSEPSKHSAECD-------PR 673 P ++ L A A P+AR +PS A T + P S + P+ Sbjct: 1070 LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1129 Query: 674 FPSVIPETSEGESSDHTTNRFGDRESSSSDEEG--GAQS 710 P V T ESSD + + S D EG GA+S Sbjct: 1130 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1168 Score = 30.8 bits (68), Expect = 5.0 Identities = 67/300 (22%), Positives = 102/300 (34%), Gaps = 54/300 (18%) Query: 324 EAGPARARAYI---DRLLHLWGRETPAKGSEGE---QGPLRHAASPSPQRQGGWSTDGG- 376 E PA R+ + +++L + PAKG+ G+ P A + + Q + G + Sbjct: 281 EEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSE 340 Query: 377 -----------------GRLLVFAPGREDEGGPAQS-------RGAGRGGPQQQGYMPLE 412 L A G+ + G A + +GA P + G P Sbjct: 341 SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG--PAV 398 Query: 413 GPQQSGSLPEEGSKPSN-SCVLRETMVQASPSSKAQQT-----PSAQDYGRGNIISPSRM 466 Q+G E+ S S E QA PS KA Q P+ + +G +P R Sbjct: 399 AKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRK 458 Query: 467 LDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLL-----LLDRP 521 P+ A + S E + +V + P + + P Sbjct: 459 T--GPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGP 516 Query: 522 EGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQE 581 G A P P + PA P+ + G WE S SE + VP AVAP + Sbjct: 517 LGKGAGPVPPGKVGPAT-PSAQVG-------KWEEDSESSSEESSDSSDGEVPTAVAPAQ 568 >gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo sapiens] Length = 1411 Score = 40.0 bits (92), Expect = 0.008 Identities = 129/579 (22%), Positives = 191/579 (32%), Gaps = 92/579 (15%) Query: 162 AQAHKARPSMGDWRPRSVDETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGD 221 A A A +G PR T PA A G + P + + + + Sbjct: 575 ASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVT 634 Query: 222 LDRALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHA 281 + +A GLQ +A + G L QG L P V+Q E Sbjct: 635 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL----PGKTGPTVTQVKAEKQ-------- 682 Query: 282 VALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLW 341 +++ S E+ PA + T +A PA ARA Sbjct: 683 -----------EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA--------- 722 Query: 342 GRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGR- 400 AKG+ G + AA+ + QR V P R + +RG Sbjct: 723 ---PSAKGTISAPGKVVTAAAQAKQRSPS---------KVKPPVRNPQNSTVLARGPASV 770 Query: 401 ---GGPQQQGYMPLEGPQQ-SGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYG 456 G GP++ SGS EE + ET+ Q PS K Q +A Sbjct: 771 PSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA----ETLAQVKPSGKTHQIRAALAPA 826 Query: 457 RGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIK---RSPMDKVLRFARQ 513 + SP + +P +G PS A + K S +E+ +P + Sbjct: 827 KE---SPRKGAAPTPPGKTG----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 879 Query: 514 PLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-----ESTLYP 568 P L+ P + A P + PA + R A A E+ RS S E + Sbjct: 880 PPLIFVDPNRSPAGPAAT----PAQ---AQAASTPRKARASESTARSSSSESEDEDVIPA 932 Query: 569 MPVLVP-----LAVAPQESHRTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLAS 623 L P + P R + +A +S S ++ + ++ AS Sbjct: 933 TQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPAS 992 Query: 624 CP--ESNLGPPRPVARRAGGPLARGRPSLVRQDAY-TRSDSEPSKHSAECD-------PR 673 P ++ L A A P+AR +PS A T + P S + P+ Sbjct: 993 LPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPK 1052 Query: 674 FPSVIPETSEGESSDHTTNRFGDRESSSSDEEG--GAQS 710 P V T ESSD + + S D EG GA+S Sbjct: 1053 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKS 1091 >gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] Length = 1444 Score = 40.0 bits (92), Expect = 0.008 Identities = 65/269 (24%), Positives = 100/269 (37%), Gaps = 42/269 (15%) Query: 467 LDKSPSPAS----GHFAHPSFAASLKMGPPKSKAEKIKRSPMDK-------VLRFARQPL 515 L+K P+P G A +++L+ P +++AE + MD+ + +Q L Sbjct: 602 LEKRPNPEKVVEEGREAGEMESSTLQESP-RARAEAVLLHEMDEDDLANALIWPEIQQEL 660 Query: 516 LLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPL 575 +++ E + P P+L+ P P L P + E PG S +P PV PL Sbjct: 661 KIIESEEELSSLPPPALKTSPIQ-PILESSLG--PFIPSEPPGSLPCGS--FPAPVSTPL 715 Query: 576 AVAPQESHRTSAQA---------------LFPFEASLLT-SVARRKHRRWQSTVEISARA 619 V ++ S Q L P ASL + + Q+TVE+ Sbjct: 716 EVWTRDPANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKASPQATVEVGG-- 773 Query: 620 RLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSDSEPS-KHSAECDPRFPSVI 678 NL PP P A PL P L+ + R DS + D Sbjct: 774 ------PGNLSPPLPPAPPPPTPLEESTPVLLSKGGPEREDSSRKLRTDLYIDQLKSQDS 827 Query: 679 PETSEGESSDHTTNRFGDRESSSSDEEGG 707 PE S + T R D+++S + G Sbjct: 828 PEISSLCQGEEATPRHSDKQNSKNAASEG 856 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.131 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,499,058 Number of Sequences: 37866 Number of extensions: 2323097 Number of successful extensions: 10068 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 353 Number of HSP's that attempted gapping in prelim test: 8776 Number of HSP's gapped (non-prelim): 1722 length of query: 774 length of database: 18,247,518 effective HSP length: 110 effective length of query: 664 effective length of database: 14,082,258 effective search space: 9350619312 effective search space used: 9350619312 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.