Search of human proteins with 157266317

Search of human proteins with 157266317

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157266317 ataxia telangiectasia and Rad3 related protein
[Homo sapiens]
         (2644 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom...  5284   0.0  
gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad...  4196   0.0  
gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad...   801   0.0  
gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens]    228   8e-59
gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]    228   8e-59
gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, pa...   228   8e-59
gi|4826730 FK506 binding protein 12-rapamycin associated protein...   197   9e-50
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]           186   3e-46
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide...   159   5e-38
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid...   142   6e-33
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated...   142   6e-33
gi|4507691 transformation/transcription domain-associated protei...    92   5e-18
gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapi...    62   6e-09
gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypept...    54   2e-06
gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo sa...    49   5e-05
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid...    49   9e-05
gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo...    48   1e-04
gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo sa...    48   1e-04
gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 ...    44   0.002
gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ...    44   0.002
gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid...    43   0.004
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept...    42   0.008
gi|239757646 PREDICTED: similar to phosphatidylinositol 4-kinase...    41   0.018
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide...    38   0.12 
gi|21361794 TIP120 protein [Homo sapiens]                              36   0.44 
gi|153791158 keratin 75 [Homo sapiens]                                 35   1.3  
gi|4507947 tyrosyl-tRNA synthetase [Homo sapiens]                      33   2.9  
gi|89886470 hypothetical protein LOC84960 [Homo sapiens]               33   4.9  
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       32   6.4  
gi|19913369 transducin beta-like 3 [Homo sapiens]                      32   6.4  

>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
            sapiens]
          Length = 2644

 Score = 5284 bits (13707), Expect = 0.0
 Identities = 2644/2644 (100%), Positives = 2644/2644 (100%)

Query: 1    MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTD 60
            MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTD
Sbjct: 1    MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTD 60

Query: 61   SQPTSVMLLDFIQHIMKSSPLMFVNVSGSHEAKGSCIEFSNWIITRLLRIAATPSCHLLH 120
            SQPTSVMLLDFIQHIMKSSPLMFVNVSGSHEAKGSCIEFSNWIITRLLRIAATPSCHLLH
Sbjct: 61   SQPTSVMLLDFIQHIMKSSPLMFVNVSGSHEAKGSCIEFSNWIITRLLRIAATPSCHLLH 120

Query: 121  KKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLS 180
            KKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLS
Sbjct: 121  KKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLS 180

Query: 181  QLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYG 240
            QLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYG
Sbjct: 181  QLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYG 240

Query: 241  SPKIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIK 300
            SPKIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIK
Sbjct: 241  SPKIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIK 300

Query: 301  TLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAG 360
            TLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAG
Sbjct: 301  TLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAG 360

Query: 361  YESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENL 420
            YESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENL
Sbjct: 361  YESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENL 420

Query: 421  SSNSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYS 480
            SSNSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYS
Sbjct: 421  SSNSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYS 480

Query: 481  GLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFY 540
            GLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFY
Sbjct: 481  GLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFY 540

Query: 541  TKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIY 600
            TKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIY
Sbjct: 541  TKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIY 600

Query: 601  SHSDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWAL 660
            SHSDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWAL
Sbjct: 601  SHSDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWAL 660

Query: 661  QSSHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHG 720
            QSSHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHG
Sbjct: 661  QSSHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHG 720

Query: 721  MFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKL 780
            MFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKL
Sbjct: 721  MFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKL 780

Query: 781  AFIDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDG 840
            AFIDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDG
Sbjct: 781  AFIDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDG 840

Query: 841  FIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKS 900
            FIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKS
Sbjct: 841  FIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKS 900

Query: 901  ASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVR 960
            ASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVR
Sbjct: 901  ASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVR 960

Query: 961  KQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQ 1020
            KQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQ
Sbjct: 961  KQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQ 1020

Query: 1021 LNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELL 1080
            LNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELL
Sbjct: 1021 LNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELL 1080

Query: 1081 LRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLS 1140
            LRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLS
Sbjct: 1081 LRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLS 1140

Query: 1141 SSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFV 1200
            SSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFV
Sbjct: 1141 SSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFV 1200

Query: 1201 RCLDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPE 1260
            RCLDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPE
Sbjct: 1201 RCLDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPE 1260

Query: 1261 LKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIK 1320
            LKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIK
Sbjct: 1261 LKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIK 1320

Query: 1321 YATDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKD 1380
            YATDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKD
Sbjct: 1321 YATDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKD 1380

Query: 1381 FTFVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGH 1440
            FTFVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGH
Sbjct: 1381 FTFVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGH 1440

Query: 1441 QLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLIT 1500
            QLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLIT
Sbjct: 1441 QLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLIT 1500

Query: 1501 KVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDD 1560
            KVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDD
Sbjct: 1501 KVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDD 1560

Query: 1561 QHTINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMVST 1620
            QHTINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMVST
Sbjct: 1561 QHTINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMVST 1620

Query: 1621 VDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLY 1680
            VDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLY
Sbjct: 1621 VDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLY 1680

Query: 1681 AAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVV 1740
            AAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVV
Sbjct: 1681 AAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVV 1740

Query: 1741 KSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTW 1800
            KSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTW
Sbjct: 1741 KSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTW 1800

Query: 1801 SVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCEL 1860
            SVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCEL
Sbjct: 1801 SVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCEL 1860

Query: 1861 EHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMV 1920
            EHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMV
Sbjct: 1861 EHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMV 1920

Query: 1921 GECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGV 1980
            GECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGV
Sbjct: 1921 GECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGV 1980

Query: 1981 ELCFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHF 2040
            ELCFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHF
Sbjct: 1981 ELCFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHF 2040

Query: 2041 YLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTK 2100
            YLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTK
Sbjct: 2041 YLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTK 2100

Query: 2101 AYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVL 2160
            AYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVL
Sbjct: 2101 AYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVL 2160

Query: 2161 MEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTD 2220
            MEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTD
Sbjct: 2161 MEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTD 2220

Query: 2221 KLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANH 2280
            KLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANH
Sbjct: 2221 KLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANH 2280

Query: 2281 ASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLME 2340
            ASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLME
Sbjct: 2281 ASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLME 2340

Query: 2341 FNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVY 2400
            FNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVY
Sbjct: 2341 FNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVY 2400

Query: 2401 MTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRS 2460
            MTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRS
Sbjct: 2401 MTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRS 2460

Query: 2461 TAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMV 2520
            TAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMV
Sbjct: 2461 TAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMV 2520

Query: 2521 NGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNET 2580
            NGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNET
Sbjct: 2521 NGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNET 2580

Query: 2581 GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGW 2640
            GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGW
Sbjct: 2581 GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGW 2640

Query: 2641 TPYM 2644
            TPYM
Sbjct: 2641 TPYM 2644


>gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad3
            related protein, partial [Homo sapiens]
          Length = 2105

 Score = 4196 bits (10882), Expect = 0.0
 Identities = 2105/2105 (100%), Positives = 2105/2105 (100%)

Query: 243  KIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIKTL 302
            KIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIKTL
Sbjct: 1    KIKSLAISFLTELFQLGGLPAQPASTFFSSFLELLKHLVEMDTDQLKLYEEPLSKLIKTL 60

Query: 303  FPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAGYE 362
            FPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAGYE
Sbjct: 61   FPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAGYE 120

Query: 363  SALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSS 422
            SALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSS
Sbjct: 121  SALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSS 180

Query: 423  NSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYSGL 482
            NSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYSGL
Sbjct: 181  NSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYSGL 240

Query: 483  KNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFYTK 542
            KNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFYTK
Sbjct: 241  KNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFYTK 300

Query: 543  VLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSH 602
            VLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSH
Sbjct: 301  VLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSH 360

Query: 603  SDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWALQS 662
            SDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWALQS
Sbjct: 361  SDDGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWALQS 420

Query: 663  SHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHGMF 722
            SHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHGMF
Sbjct: 421  SHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHGMF 480

Query: 723  YLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAF 782
            YLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAF
Sbjct: 481  YLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAF 540

Query: 783  IDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDGFI 842
            IDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDGFI
Sbjct: 541  IDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDGFI 600

Query: 843  KELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKSAS 902
            KELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKSAS
Sbjct: 601  KELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKSAS 660

Query: 903  VSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQ 962
            VSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQ
Sbjct: 661  VSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQ 720

Query: 963  DVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLN 1022
            DVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLN
Sbjct: 721  DVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLN 780

Query: 1023 VNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLR 1082
            VNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLR
Sbjct: 781  VNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELLLR 840

Query: 1083 IGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSS 1142
            IGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSS
Sbjct: 841  IGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSS 900

Query: 1143 VGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRC 1202
            VGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRC
Sbjct: 901  VGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRC 960

Query: 1203 LDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPELK 1262
            LDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPELK
Sbjct: 961  LDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPELK 1020

Query: 1263 KIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIKYA 1322
            KIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIKYA
Sbjct: 1021 KIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIKYA 1080

Query: 1323 TDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKDFT 1382
            TDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKDFT
Sbjct: 1081 TDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKDFT 1140

Query: 1383 FVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGHQL 1442
            FVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGHQL
Sbjct: 1141 FVTGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGPGHQL 1200

Query: 1443 WRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLITKV 1502
            WRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLITKV
Sbjct: 1201 WRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLITKV 1260

Query: 1503 RHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDDQH 1562
            RHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDDQH
Sbjct: 1261 RHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDDQH 1320

Query: 1563 TINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMVSTVD 1622
            TINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMVSTVD
Sbjct: 1321 TINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMVSTVD 1380

Query: 1623 YEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLYAA 1682
            YEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLYAA
Sbjct: 1381 YEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLYAA 1440

Query: 1683 MHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKS 1742
            MHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKS
Sbjct: 1441 MHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKS 1500

Query: 1743 MLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSV 1802
            MLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSV
Sbjct: 1501 MLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKSTTWSV 1560

Query: 1803 RLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCELEH 1862
            RLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCELEH
Sbjct: 1561 RLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCELEH 1620

Query: 1863 SIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMVGE 1922
            SIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMVGE
Sbjct: 1621 SIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMVGE 1680

Query: 1923 CWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVEL 1982
            CWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVEL
Sbjct: 1681 CWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQKGVEL 1740

Query: 1983 CFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHFYL 2042
            CFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHFYL
Sbjct: 1741 CFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDGHFYL 1800

Query: 2043 AKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTKAY 2102
            AKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTKAY
Sbjct: 1801 AKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYGTKAY 1860

Query: 2103 EWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLME 2162
            EWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLME
Sbjct: 1861 EWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLME 1920

Query: 2163 IIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKL 2222
            IIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKL
Sbjct: 1921 IIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKL 1980

Query: 2223 LELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANHAS 2282
            LELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANHAS
Sbjct: 1981 LELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANHAS 2040

Query: 2283 HEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFN 2342
            HEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFN
Sbjct: 2041 HEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFN 2100

Query: 2343 SLINK 2347
            SLINK
Sbjct: 2101 SLINK 2105


>gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad3
            related protein, partial [Homo sapiens]
          Length = 386

 Score =  801 bits (2068), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 2259 LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSD 2318
            LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSD
Sbjct: 1    LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSD 60

Query: 2319 GKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIE 2378
            GKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIE
Sbjct: 61   GKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIE 120

Query: 2379 WVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHE 2438
            WVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHE
Sbjct: 121  WVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHE 180

Query: 2439 WFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCL 2498
            WFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCL
Sbjct: 181  WFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCL 240

Query: 2499 FNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFL 2558
            FNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFL
Sbjct: 241  FNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFL 300

Query: 2559 HDPLVEWSKPVKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEG 2618
            HDPLVEWSKPVKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEG
Sbjct: 301  HDPLVEWSKPVKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEG 360

Query: 2619 HVHYLIQEATDENLLCQMYLGWTPYM 2644
            HVHYLIQEATDENLLCQMYLGWTPYM
Sbjct: 361  HVHYLIQEATDENLLCQMYLGWTPYM 386


>gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens]
          Length = 1708

 Score =  228 bits (580), Expect = 8e-59
 Identities = 163/548 (29%), Positives = 257/548 (46%), Gaps = 53/548 (9%)

Query: 2130 TNYLAPYQFLTAFSQLISRIC--HSHDEVFVVLMEIIAK--VFLAYPQQAMWMMTA--VS 2183
            T  +    F    + LISRI   H H  +F++L    A    FL  P+ A        V 
Sbjct: 1181 TKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVP 1240

Query: 2184 KSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHF 2243
            K S  +  +R +        ++    + V     L D  + L N            +T +
Sbjct: 1241 KQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLD----------ATQW 1290

Query: 2244 KMLKKLVEEATFSEI--LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVE 2301
            K  +K +       I  L  L+ V++PT+            H    G+   I  F     
Sbjct: 1291 KTQRKGINIPADQPITKLKNLEDVVVPTMEI-------KVDHTGEYGNLVTIQSFKAEFR 1343

Query: 2302 ILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELH 2361
            +   +  PK I   GSDGK    + K +DDLR+D  + +   + N  L+++ E+R+R+L 
Sbjct: 1344 LAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLT 1403

Query: 2362 IRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKE--------LRQCMLPK 2413
            I TY V+PL+   G++EW   T  +   L     E G +   +          ++ M  +
Sbjct: 1404 ICTYKVVPLSQRSGVLEWCTGTVPIGEFLVN--NEDGAHKRYRPNDFSAFQCQKKMMEVQ 1461

Query: 2414 SAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGL 2473
              +  EK +VF + +     P+F  + +  F DP  W+  R AY RS A  S+VGYILGL
Sbjct: 1462 KKSFEEKYEVFMD-VCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGL 1520

Query: 2474 GDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFR 2533
            GDRH +NIL +  + E VH+D    F +G+    PE VPFRLT ++V+GMG  G EG+FR
Sbjct: 1521 GDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFR 1580

Query: 2534 RACEVTMRLMRDQREPLMSVLKTFLHDPLVEWS-KPVKG-------HSKAPLNETGEVVN 2585
            R CE TM +MR+ +E L+++++  L+DPL +W+  P+K          +  L+ T    +
Sbjct: 1581 RCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADD 1640

Query: 2586 EKAKTHVLDIEQRLQGVI---------KTRNRVTGLPLSIEGHVHYLIQEATDENLLCQM 2636
            ++ K ++ DI+Q    V          K +    G  LS+ G V+ LIQ+A D   L ++
Sbjct: 1641 QECKRNLSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRL 1700

Query: 2637 YLGWTPYM 2644
            + GW  ++
Sbjct: 1701 FPGWKAWV 1708



 Score =  119 bits (298), Expect = 4e-26
 Identities = 198/919 (21%), Positives = 368/919 (40%), Gaps = 135/919 (14%)

Query: 1191 LCCRAWDCFVRCLDHACLGSLLSH---VIVALLPLIHIQ---PKETAAIFHYLIIENRDA 1244
            LCC       +     C  +L +H   ++  L+PL++ Q    K+   +  YL+I+N+D 
Sbjct: 145  LCCDLLSQVCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDN 204

Query: 1245 VQDFLHEIYFL---PDHPELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRI 1301
               ++  I  L   PDH   K ++   Q+ +      + L+        ++       R+
Sbjct: 205  ENLYI-TIKLLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRL 263

Query: 1302 HALTSLKETL--YKNQEKLIKYATDSETVEPIISQLVTVLLKGCQDA-----NSQARLLC 1354
              L  L+  L  +K+Q   I  A+     + I+ +LV  LL+  + A       +     
Sbjct: 264  EGLKDLRRQLELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAV 323

Query: 1355 GECLGELGAIDPGRLDFSTTETQ-GKDFTFVTGV---EDSSFAYGLLMELTRAYLAYADN 1410
            G CLGE+G ID     FST   Q  KD ++   +   ED    +  +M      L Y +N
Sbjct: 324  GSCLGEVGPID-----FSTIAIQHSKDASYTKALKLFEDKELQWTFIM------LTYLNN 372

Query: 1411 SRAQDSAAYAIQELLSIYDCREMETNGPGHQLWRRFPEHVREILEPHLNTRYKSSQ---- 1466
            +  +D        +  + +    +T     ++++   + +   L+P   +R K  +    
Sbjct: 373  TLVEDCVKVRSAAVTCLKNILATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRF 432

Query: 1467 -KSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLITK--VRHDLASKIFTCCSIMMKHDFK 1523
             K   + G+        L  N   W  +     +     + ++   +   C +  K DF 
Sbjct: 433  DKENPFEGLDDINLWIPLSENHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEV--KTDFC 490

Query: 1524 VTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDDQHTINTQDIASDLCQLSTQTVFS 1583
             T+  LP+++  +LL    +D  E +  +++          + Q   +   +  +QT  S
Sbjct: 491  QTV--LPYLIHDILL----QDTNESWRNLLST---------HVQGFFTSCLRHFSQTSRS 535

Query: 1584 MLD-HLTQWARHKFQALKAEKCPHSKSNRNKVDSMVSTVDYEDYQ----SVTRFLDLIPQ 1638
                +L   + H F+      C   KS R    +M++ VDY   Q    S T F D    
Sbjct: 536  TTPANLDSESEHFFRC-----CLDKKSQR----TMLAVVDYMRRQKRPSSGTIFNDAFWL 586

Query: 1639 DT----LAVASFRSKAYTRAVMHFESFITEKKQNIQEH--LGF----------------- 1675
            D     +A  +    A+  A+++ E +  +K  + QE   L F                 
Sbjct: 587  DLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEGSQSTTISSLSEKSK 646

Query: 1676 ----------LQKLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRA 1725
                      L ++Y ++ EPD + G    +  +P  + +  EHE++      T   + A
Sbjct: 647  EETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEAMWGKALVTYDLETA 706

Query: 1726 IQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWD 1785
            I     Q     G+++++  LG    +   + G+     +W  EL     +AAW+  QWD
Sbjct: 707  IPSSTRQA----GIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHYQAAWRNMQWD 762

Query: 1786 LVENYLAADGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQ 1845
               + ++ + + T++   L   L S + R+ + FY+SLK  R +++  +   S E  S  
Sbjct: 763  HCTS-VSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCKRSLE--SVY 819

Query: 1846 RGYEYIVRLHMLCELEHSIKPLFQHSPGDSS-QEDSLNWVARLEMTQNS-YRAKEPILAL 1903
              Y  + RL  + ELE SI  LF  S       E  + W    ++ ++S +  +EPI+AL
Sbjct: 820  SLYPTLSRLQAIGELE-SIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMAL 878

Query: 1904 RRALLSLNKRPDYNEMVGEC--------WLQSARVARKAGHHQTAYNALL-----NAGES 1950
            R  +L +    + +    EC         ++ + +AR   + Q    A+      N+   
Sbjct: 879  RTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSC 938

Query: 1951 RLAELYVERAKWLWSKGDVHQALIVLQKGVE----LCFPENETPPEGKNMLIHGRAMLLV 2006
             ++E  +E A+  W+K +   AL +L++ ++     C   N   P  K  L +   + + 
Sbjct: 939  GVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANN---PSLK--LTYTECLRVC 993

Query: 2007 GRFMEETANFESNAIMKKY 2025
            G ++ ET       IM+ Y
Sbjct: 994  GNWLAETCLENPAVIMQTY 1012


>gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]
          Length = 3056

 Score =  228 bits (580), Expect = 8e-59
 Identities = 163/548 (29%), Positives = 257/548 (46%), Gaps = 53/548 (9%)

Query: 2130 TNYLAPYQFLTAFSQLISRIC--HSHDEVFVVLMEIIAK--VFLAYPQQAMWMMTA--VS 2183
            T  +    F    + LISRI   H H  +F++L    A    FL  P+ A        V 
Sbjct: 2529 TKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVP 2588

Query: 2184 KSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHF 2243
            K S  +  +R +        ++    + V     L D  + L N            +T +
Sbjct: 2589 KQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLD----------ATQW 2638

Query: 2244 KMLKKLVEEATFSEI--LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVE 2301
            K  +K +       I  L  L+ V++PT+            H    G+   I  F     
Sbjct: 2639 KTQRKGINIPADQPITKLKNLEDVVVPTMEI-------KVDHTGEYGNLVTIQSFKAEFR 2691

Query: 2302 ILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELH 2361
            +   +  PK I   GSDGK    + K +DDLR+D  + +   + N  L+++ E+R+R+L 
Sbjct: 2692 LAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLT 2751

Query: 2362 IRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKE--------LRQCMLPK 2413
            I TY V+PL+   G++EW   T  +   L     E G +   +          ++ M  +
Sbjct: 2752 ICTYKVVPLSQRSGVLEWCTGTVPIGEFLVN--NEDGAHKRYRPNDFSAFQCQKKMMEVQ 2809

Query: 2414 SAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGL 2473
              +  EK +VF + +     P+F  + +  F DP  W+  R AY RS A  S+VGYILGL
Sbjct: 2810 KKSFEEKYEVFMD-VCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGL 2868

Query: 2474 GDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFR 2533
            GDRH +NIL +  + E VH+D    F +G+    PE VPFRLT ++V+GMG  G EG+FR
Sbjct: 2869 GDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFR 2928

Query: 2534 RACEVTMRLMRDQREPLMSVLKTFLHDPLVEWS-KPVKG-------HSKAPLNETGEVVN 2585
            R CE TM +MR+ +E L+++++  L+DPL +W+  P+K          +  L+ T    +
Sbjct: 2929 RCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADD 2988

Query: 2586 EKAKTHVLDIEQRLQGVI---------KTRNRVTGLPLSIEGHVHYLIQEATDENLLCQM 2636
            ++ K ++ DI+Q    V          K +    G  LS+ G V+ LIQ+A D   L ++
Sbjct: 2989 QECKRNLSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRL 3048

Query: 2637 YLGWTPYM 2644
            + GW  ++
Sbjct: 3049 FPGWKAWV 3056



 Score =  119 bits (298), Expect = 4e-26
 Identities = 198/919 (21%), Positives = 368/919 (40%), Gaps = 135/919 (14%)

Query: 1191 LCCRAWDCFVRCLDHACLGSLLSH---VIVALLPLIHIQ---PKETAAIFHYLIIENRDA 1244
            LCC       +     C  +L +H   ++  L+PL++ Q    K+   +  YL+I+N+D 
Sbjct: 1493 LCCDLLSQVCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDN 1552

Query: 1245 VQDFLHEIYFL---PDHPELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRI 1301
               ++  I  L   PDH   K ++   Q+ +      + L+        ++       R+
Sbjct: 1553 ENLYI-TIKLLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRL 1611

Query: 1302 HALTSLKETL--YKNQEKLIKYATDSETVEPIISQLVTVLLKGCQDA-----NSQARLLC 1354
              L  L+  L  +K+Q   I  A+     + I+ +LV  LL+  + A       +     
Sbjct: 1612 EGLKDLRRQLELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAV 1671

Query: 1355 GECLGELGAIDPGRLDFSTTETQ-GKDFTFVTGV---EDSSFAYGLLMELTRAYLAYADN 1410
            G CLGE+G ID     FST   Q  KD ++   +   ED    +  +M      L Y +N
Sbjct: 1672 GSCLGEVGPID-----FSTIAIQHSKDASYTKALKLFEDKELQWTFIM------LTYLNN 1720

Query: 1411 SRAQDSAAYAIQELLSIYDCREMETNGPGHQLWRRFPEHVREILEPHLNTRYKSSQ---- 1466
            +  +D        +  + +    +T     ++++   + +   L+P   +R K  +    
Sbjct: 1721 TLVEDCVKVRSAAVTCLKNILATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRF 1780

Query: 1467 -KSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLITK--VRHDLASKIFTCCSIMMKHDFK 1523
             K   + G+        L  N   W  +     +     + ++   +   C +  K DF 
Sbjct: 1781 DKENPFEGLDDINLWIPLSENHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEV--KTDFC 1838

Query: 1524 VTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDDQHTINTQDIASDLCQLSTQTVFS 1583
             T+  LP+++  +LL    +D  E +  +++          + Q   +   +  +QT  S
Sbjct: 1839 QTV--LPYLIHDILL----QDTNESWRNLLST---------HVQGFFTSCLRHFSQTSRS 1883

Query: 1584 MLD-HLTQWARHKFQALKAEKCPHSKSNRNKVDSMVSTVDYEDYQ----SVTRFLDLIPQ 1638
                +L   + H F+      C   KS R    +M++ VDY   Q    S T F D    
Sbjct: 1884 TTPANLDSESEHFFRC-----CLDKKSQR----TMLAVVDYMRRQKRPSSGTIFNDAFWL 1934

Query: 1639 DT----LAVASFRSKAYTRAVMHFESFITEKKQNIQEH--LGF----------------- 1675
            D     +A  +    A+  A+++ E +  +K  + QE   L F                 
Sbjct: 1935 DLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEGSQSTTISSLSEKSK 1994

Query: 1676 ----------LQKLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRA 1725
                      L ++Y ++ EPD + G    +  +P  + +  EHE++      T   + A
Sbjct: 1995 EETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEAMWGKALVTYDLETA 2054

Query: 1726 IQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWD 1785
            I     Q     G+++++  LG    +   + G+     +W  EL     +AAW+  QWD
Sbjct: 2055 IPSSTRQA----GIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHYQAAWRNMQWD 2110

Query: 1786 LVENYLAADGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQ 1845
               + ++ + + T++   L   L S + R+ + FY+SLK  R +++  +   S E  S  
Sbjct: 2111 HCTS-VSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCKRSLE--SVY 2167

Query: 1846 RGYEYIVRLHMLCELEHSIKPLFQHSPGDSS-QEDSLNWVARLEMTQNS-YRAKEPILAL 1903
              Y  + RL  + ELE SI  LF  S       E  + W    ++ ++S +  +EPI+AL
Sbjct: 2168 SLYPTLSRLQAIGELE-SIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMAL 2226

Query: 1904 RRALLSLNKRPDYNEMVGEC--------WLQSARVARKAGHHQTAYNALL-----NAGES 1950
            R  +L +    + +    EC         ++ + +AR   + Q    A+      N+   
Sbjct: 2227 RTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSC 2286

Query: 1951 RLAELYVERAKWLWSKGDVHQALIVLQKGVE----LCFPENETPPEGKNMLIHGRAMLLV 2006
             ++E  +E A+  W+K +   AL +L++ ++     C   N   P  K  L +   + + 
Sbjct: 2287 GVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANN---PSLK--LTYTECLRVC 2341

Query: 2007 GRFMEETANFESNAIMKKY 2025
            G ++ ET       IM+ Y
Sbjct: 2342 GNWLAETCLENPAVIMQTY 2360


>gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, partial
            [Homo sapiens]
          Length = 2934

 Score =  228 bits (580), Expect = 8e-59
 Identities = 163/548 (29%), Positives = 257/548 (46%), Gaps = 53/548 (9%)

Query: 2130 TNYLAPYQFLTAFSQLISRIC--HSHDEVFVVLMEIIAK--VFLAYPQQAMWMMTA--VS 2183
            T  +    F    + LISRI   H H  +F++L    A    FL  P+ A        V 
Sbjct: 2407 TKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVP 2466

Query: 2184 KSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHF 2243
            K S  +  +R +        ++    + V     L D  + L N            +T +
Sbjct: 2467 KQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLD----------ATQW 2516

Query: 2244 KMLKKLVEEATFSEI--LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVE 2301
            K  +K +       I  L  L+ V++PT+            H    G+   I  F     
Sbjct: 2517 KTQRKGINIPADQPITKLKNLEDVVVPTMEI-------KVDHTGEYGNLVTIQSFKAEFR 2569

Query: 2302 ILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELH 2361
            +   +  PK I   GSDGK    + K +DDLR+D  + +   + N  L+++ E+R+R+L 
Sbjct: 2570 LAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLT 2629

Query: 2362 IRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKE--------LRQCMLPK 2413
            I TY V+PL+   G++EW   T  +   L     E G +   +          ++ M  +
Sbjct: 2630 ICTYKVVPLSQRSGVLEWCTGTVPIGEFLVN--NEDGAHKRYRPNDFSAFQCQKKMMEVQ 2687

Query: 2414 SAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGL 2473
              +  EK +VF + +     P+F  + +  F DP  W+  R AY RS A  S+VGYILGL
Sbjct: 2688 KKSFEEKYEVFMD-VCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGL 2746

Query: 2474 GDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFR 2533
            GDRH +NIL +  + E VH+D    F +G+    PE VPFRLT ++V+GMG  G EG+FR
Sbjct: 2747 GDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFR 2806

Query: 2534 RACEVTMRLMRDQREPLMSVLKTFLHDPLVEWS-KPVKG-------HSKAPLNETGEVVN 2585
            R CE TM +MR+ +E L+++++  L+DPL +W+  P+K          +  L+ T    +
Sbjct: 2807 RCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADD 2866

Query: 2586 EKAKTHVLDIEQRLQGVI---------KTRNRVTGLPLSIEGHVHYLIQEATDENLLCQM 2636
            ++ K ++ DI+Q    V          K +    G  LS+ G V+ LIQ+A D   L ++
Sbjct: 2867 QECKRNLSDIDQSFDKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRL 2926

Query: 2637 YLGWTPYM 2644
            + GW  ++
Sbjct: 2927 FPGWKAWV 2934



 Score =  119 bits (298), Expect = 4e-26
 Identities = 198/919 (21%), Positives = 368/919 (40%), Gaps = 135/919 (14%)

Query: 1191 LCCRAWDCFVRCLDHACLGSLLSH---VIVALLPLIHIQ---PKETAAIFHYLIIENRDA 1244
            LCC       +     C  +L +H   ++  L+PL++ Q    K+   +  YL+I+N+D 
Sbjct: 1371 LCCDLLSQVCQTAVTYCKDALENHLHVIVGTLIPLVYEQVEVQKQVLDLLKYLVIDNKDN 1430

Query: 1245 VQDFLHEIYFL---PDHPELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRI 1301
               ++  I  L   PDH   K ++   Q+ +      + L+        ++       R+
Sbjct: 1431 ENLYI-TIKLLDPFPDHVVFKDLRITQQKIKYSRGPFSLLEEINHFLSVSVYDALPLTRL 1489

Query: 1302 HALTSLKETL--YKNQEKLIKYATDSETVEPIISQLVTVLLKGCQDA-----NSQARLLC 1354
              L  L+  L  +K+Q   I  A+     + I+ +LV  LL+  + A       +     
Sbjct: 1490 EGLKDLRRQLELHKDQMVDIMRASQDNPQDGIMVKLVVNLLQLSKMAINHTGEKEVLEAV 1549

Query: 1355 GECLGELGAIDPGRLDFSTTETQ-GKDFTFVTGV---EDSSFAYGLLMELTRAYLAYADN 1410
            G CLGE+G ID     FST   Q  KD ++   +   ED    +  +M      L Y +N
Sbjct: 1550 GSCLGEVGPID-----FSTIAIQHSKDASYTKALKLFEDKELQWTFIM------LTYLNN 1598

Query: 1411 SRAQDSAAYAIQELLSIYDCREMETNGPGHQLWRRFPEHVREILEPHLNTRYKSSQ---- 1466
            +  +D        +  + +    +T     ++++   + +   L+P   +R K  +    
Sbjct: 1599 TLVEDCVKVRSAAVTCLKNILATKTGHSFWEIYKMTTDPMLAYLQPFRTSRKKFLEVPRF 1658

Query: 1467 -KSTDWSGVKKPIYLSKLGSNFAEWSASWAGYLITK--VRHDLASKIFTCCSIMMKHDFK 1523
             K   + G+        L  N   W  +     +     + ++   +   C +  K DF 
Sbjct: 1659 DKENPFEGLDDINLWIPLSENHDIWIKTLTCAFLDSGGTKCEILQLLKPMCEV--KTDFC 1716

Query: 1524 VTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKHDDQHTINTQDIASDLCQLSTQTVFS 1583
             T+  LP+++  +LL    +D  E +  +++          + Q   +   +  +QT  S
Sbjct: 1717 QTV--LPYLIHDILL----QDTNESWRNLLST---------HVQGFFTSCLRHFSQTSRS 1761

Query: 1584 MLD-HLTQWARHKFQALKAEKCPHSKSNRNKVDSMVSTVDYEDYQ----SVTRFLDLIPQ 1638
                +L   + H F+      C   KS R    +M++ VDY   Q    S T F D    
Sbjct: 1762 TTPANLDSESEHFFRC-----CLDKKSQR----TMLAVVDYMRRQKRPSSGTIFNDAFWL 1812

Query: 1639 DT----LAVASFRSKAYTRAVMHFESFITEKKQNIQEH--LGF----------------- 1675
            D     +A  +    A+  A+++ E +  +K  + QE   L F                 
Sbjct: 1813 DLNYLEVAKVAQSCAAHFTALLYAEIYADKKSMDDQEKRSLAFEEGSQSTTISSLSEKSK 1872

Query: 1676 ----------LQKLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRA 1725
                      L ++Y ++ EPD + G    +  +P  + +  EHE++      T   + A
Sbjct: 1873 EETGISLQDLLLEIYRSIGEPDSLYGCGGGKMLQPITRLRTYEHEAMWGKALVTYDLETA 1932

Query: 1726 IQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWD 1785
            I     Q     G+++++  LG    +   + G+     +W  EL     +AAW+  QWD
Sbjct: 1933 IPSSTRQA----GIIQALQNLGLCHILSVYLKGLDYENKDWCPELEELHYQAAWRNMQWD 1988

Query: 1786 LVENYLAADGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQ 1845
               + ++ + + T++   L   L S + R+ + FY+SLK  R +++  +   S E  S  
Sbjct: 1989 HCTS-VSKEVEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEEMCKRSLE--SVY 2045

Query: 1846 RGYEYIVRLHMLCELEHSIKPLFQHSPGDSS-QEDSLNWVARLEMTQNS-YRAKEPILAL 1903
              Y  + RL  + ELE SI  LF  S       E  + W    ++ ++S +  +EPI+AL
Sbjct: 2046 SLYPTLSRLQAIGELE-SIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMAL 2104

Query: 1904 RRALLSLNKRPDYNEMVGEC--------WLQSARVARKAGHHQTAYNALL-----NAGES 1950
            R  +L +    + +    EC         ++ + +AR   + Q    A+      N+   
Sbjct: 2105 RTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSC 2164

Query: 1951 RLAELYVERAKWLWSKGDVHQALIVLQKGVE----LCFPENETPPEGKNMLIHGRAMLLV 2006
             ++E  +E A+  W+K +   AL +L++ ++     C   N   P  K  L +   + + 
Sbjct: 2165 GVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANN---PSLK--LTYTECLRVC 2219

Query: 2007 GRFMEETANFESNAIMKKY 2025
            G ++ ET       IM+ Y
Sbjct: 2220 GNWLAETCLENPAVIMQTY 2238


>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
            [Homo sapiens]
          Length = 2549

 Score =  197 bits (502), Expect = 9e-50
 Identities = 124/390 (31%), Positives = 198/390 (50%), Gaps = 47/390 (12%)

Query: 2300 VEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRE 2359
            ++++ S Q+P+K++L GS+G  ++ + K  +DLR+D R+M+   L+N  L  D  S R+ 
Sbjct: 2160 LQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKN 2219

Query: 2360 LHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKE----LRQCMLPKSA 2415
            L I+ YAVIPL+   G+I WV +   L  ++ + Y+EK   +   E    LR        
Sbjct: 2220 LSIQRYAVIPLSTNSGLIGWVPHCDTLHALI-RDYREKKKILLNIEHRIMLRMAPDYDHL 2278

Query: 2416 ALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGD 2475
             L +K++VF   +         +      P    W+  R+ Y RS AVMSMVGYILGLGD
Sbjct: 2279 TLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGD 2338

Query: 2476 RHGENILFDSLTGECVHVDFNCLFNKGETFE-VPEIVPFRLTHNMVNGMGPMGTEGLFRR 2534
            RH  N++ D L+G+ +H+DF   F    T E  PE +PFRLT  + N M   G +G +R 
Sbjct: 2339 RHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRI 2398

Query: 2535 ACEVTMRLMRDQREPLMSVLKTFLHDPLVEW---SKPVKGHSKAPLN------------- 2578
             C   M ++R+ ++ +M+VL+ F++DPL+ W       KG+ ++                
Sbjct: 2399 TCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEIL 2458

Query: 2579 ---ETGEVVNEKAKTHVLDI----------------EQRLQGVIKTRNRVTGL------P 2613
               E GE  ++K  T V +                 ++ +Q + + R+++TG        
Sbjct: 2459 DGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDT 2518

Query: 2614 LSIEGHVHYLIQEATDENLLCQMYLGWTPY 2643
            L +   V  LI++AT    LCQ Y+GW P+
Sbjct: 2519 LDVPTQVELLIKQATSHENLCQCYIGWCPF 2548



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 78/307 (25%), Positives = 127/307 (41%), Gaps = 29/307 (9%)

Query: 1647 RSKAYTRAVMHFESFITEKKQNIQEHLGFLQKLYAAMHEPDGVAGV-SAIRKAEPSLKEQ 1705
            + +AY +A+ + E  +  +K      L  L  +   + +P+  AGV     K    L+ Q
Sbjct: 1389 KCRAYAKALHYKE--LEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQ 1446

Query: 1706 ILEHESLGLLRDATACYDRAIQLEPDQIIHYHGVVKSMLGLGQLSTVITQVNGVHANRSE 1765
               +E L    DA   YD+ +    D      G ++ +  LG+   +  Q        ++
Sbjct: 1447 ATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVND 1506

Query: 1766 WTD-ELNTYRVEAAWKLSQWDLVENYLAA------DGKSTTWSVRLGQLLLSAKKRDITA 1818
             T  ++      AAW L QWD +E Y         DG      + L Q L S  ++ I  
Sbjct: 1507 ETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDK 1566

Query: 1819 FYDSLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLCELEHSIKPLFQHSPGDSSQE 1878
              D   L+ AE    L+A + E  SY R Y  +V  HML ELE  I+  ++  P +  + 
Sbjct: 1567 ARD---LLDAE----LTAMAGE--SYSRAYGAMVSCHMLSELEEVIQ--YKLVP-ERREI 1614

Query: 1879 DSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNEMVGECWLQSARVARKAGHHQ 1938
                W  RL+  Q      + IL +R  ++S      + +M    WL+ A +  K+G   
Sbjct: 1615 IRQIWWERLQGCQRIVEDWQKILMVRSLVVS-----PHEDM--RTWLKYASLCGKSGRLA 1667

Query: 1939 TAYNALL 1945
             A+  L+
Sbjct: 1668 LAHKTLV 1674



 Score = 41.2 bits (95), Expect = 0.014
 Identities = 37/151 (24%), Positives = 63/151 (41%), Gaps = 24/151 (15%)

Query: 2075 SLQYGNQFIYQSMPRMLTLWLDYGTKAYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLA 2134
            SL  GN    Q   R+LTLW DYG     W                 +N+ + E    + 
Sbjct: 1893 SLSRGNNL--QDTLRVLTLWFDYG----HWP---------------DVNEALVEGVKAIQ 1931

Query: 2135 PYQFLTAFSQLISRICHSHDEVFVVLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRC 2194
               +L    QLI+RI      V  ++ +++  +   +PQ  ++ +T  SKS+   R N  
Sbjct: 1932 IDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAA 1991

Query: 2195 KEILNKAIHMKKSLEKFVGDATRLTDKLLEL 2225
             +IL        +L   V  A  ++++L+ +
Sbjct: 1992 NKILKNMCEHSNTL---VQQAMMVSEELIRV 2019


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score =  186 bits (472), Expect = 3e-46
 Identities = 105/301 (34%), Positives = 152/301 (50%), Gaps = 36/301 (11%)

Query: 2300 VEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRE 2359
            + IL +  KPKK+   GSDGK Y  + K  +DL  D R+M+F S++N             
Sbjct: 2128 ITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPR 2187

Query: 2360 LHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSE 2419
             H R Y+V PL    G+I+WV+    L  +  +  + +      K       P++  +  
Sbjct: 2188 FHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQDSYQTPQNPGIVP 2247

Query: 2420 K-------------------------------LKVFREFLLPRHPPIF---HEWFLRTFP 2445
            +                               +K   E L+   PP       W   T P
Sbjct: 2248 RPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTP 2307

Query: 2446 DPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETF 2505
            D   W+    +Y RSTAVMSMVGYI+GLGDRH +N+L D  TGE VH+D+N  F KG++ 
Sbjct: 2308 D--EWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSL 2365

Query: 2506 EVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW 2565
             VPE VPFR+T N+   +G  G EG+FR +CE  + +MR  RE L+++L+ F++DPLV+W
Sbjct: 2366 RVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDW 2425

Query: 2566 S 2566
            +
Sbjct: 2426 T 2426



 Score = 38.9 bits (89), Expect = 0.068
 Identities = 19/66 (28%), Positives = 41/66 (62%), Gaps = 1/66 (1%)

Query: 2579 ETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYL 2638
            +TG+ V E+  ++ + + +R++  ++ R+      +S+   V Y+I+EAT+ + L Q+Y 
Sbjct: 3597 KTGKAVQER-NSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYE 3655

Query: 2639 GWTPYM 2644
            GWT ++
Sbjct: 3656 GWTAWV 3661


>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
            isoform 1 [Homo sapiens]
          Length = 4128

 Score =  159 bits (401), Expect = 5e-38
 Identities = 116/431 (26%), Positives = 188/431 (43%), Gaps = 82/431 (19%)

Query: 2284 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2343
            +P P +   IAGFD+ V ++ASL++PK+I ++G D + +  + K  +DLR+D R+ +   
Sbjct: 3710 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3769

Query: 2344 LINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPIL--TKLYKEKGVYM 2401
            ++N  L +D+   +R L +RTY+V+P+    G+IEW+ NT  L+ +L  T   +EK  Y+
Sbjct: 3770 VMNGILAQDSACSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYL 3829

Query: 2402 TGKELRQC-------------------MLPKSAALSEKLKVFREFLLPRHPPIFHEWFLR 2442
            +      C                   ++ K A  +E +  FR+        +    F+R
Sbjct: 3830 SDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVR 3889

Query: 2443 TFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKG 2502
                P ++ + RS +  S A++ +  +ILG+GDRH  N +    TG  + +DF   F   
Sbjct: 3890 MSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3949

Query: 2503 ETF-EVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDP 2561
              F  VPE++PFRLT   +N M PM   GL        +R  R     L + +  F+ +P
Sbjct: 3950 TQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEP 4009

Query: 2562 LVEW----SKPVK--------------------------------------------GHS 2573
              +W     K +K                                            GH 
Sbjct: 4010 SFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHE 4069

Query: 2574 KAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLL 2633
            KAP       V   +K H +  ++   G            LS E  V  L+ +ATD N+L
Sbjct: 4070 KAPAFRDYVAVARGSKDHNIRAQEPESG------------LSEETQVKCLMDQATDPNIL 4117

Query: 2634 CQMYLGWTPYM 2644
             + + GW P+M
Sbjct: 4118 GRTWEGWEPWM 4128


>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
            isoform 2 [Homo sapiens]
          Length = 4097

 Score =  142 bits (357), Expect = 6e-33
 Identities = 109/416 (26%), Positives = 178/416 (42%), Gaps = 83/416 (19%)

Query: 2284 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2343
            +P P +   IAGFD+ V ++ASL++PK+I ++G D + +  + K  +DLR+D R+ +   
Sbjct: 3710 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3769

Query: 2344 LINKCLRKDAESRRRELHIRTYAVIPLNDE------CGIIEWVNNTAGLRPILTKLYKEK 2397
            ++N  L +D+   +R L +RTY+V+P+         C   +W+   +G   +        
Sbjct: 3770 VMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDV-------- 3821

Query: 2398 GVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAY 2457
            G YM        ++ K A  +E +  FR+        +    F+R    P ++ + RS +
Sbjct: 3822 GAYM--------LMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHF 3873

Query: 2458 CRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETF-EVPEIVPFRLT 2516
              S A++ +  +ILG+GDRH  N +    TG  + +DF   F     F  VPE++PFRLT
Sbjct: 3874 ASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLT 3933

Query: 2517 HNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW----SKPVK-- 2570
               +N M PM   GL        +R  R     L + +  F+ +P  +W     K +K  
Sbjct: 3934 RQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKG 3993

Query: 2571 ------------------------------------------GHSKAPLNETGEVVNEKA 2588
                                                      GH KAP       V   +
Sbjct: 3994 GSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGS 4053

Query: 2589 KTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 2644
            K H +  ++   G            LS E  V  L+ +ATD N+L + + GW P+M
Sbjct: 4054 KDHNIRAQEPESG------------LSEETQVKCLMDQATDPNILGRTWEGWEPWM 4097


>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
            catalytic polypeptide [Homo sapiens]
          Length = 4096

 Score =  142 bits (357), Expect = 6e-33
 Identities = 109/416 (26%), Positives = 178/416 (42%), Gaps = 83/416 (19%)

Query: 2284 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2343
            +P P +   IAGFD+ V ++ASL++PK+I ++G D + +  + K  +DLR+D R+ +   
Sbjct: 3709 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3768

Query: 2344 LINKCLRKDAESRRRELHIRTYAVIPLNDE------CGIIEWVNNTAGLRPILTKLYKEK 2397
            ++N  L +D+   +R L +RTY+V+P+         C   +W+   +G   +        
Sbjct: 3769 VMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDV-------- 3820

Query: 2398 GVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAY 2457
            G YM        ++ K A  +E +  FR+        +    F+R    P ++ + RS +
Sbjct: 3821 GAYM--------LMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHF 3872

Query: 2458 CRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETF-EVPEIVPFRLT 2516
              S A++ +  +ILG+GDRH  N +    TG  + +DF   F     F  VPE++PFRLT
Sbjct: 3873 ASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLT 3932

Query: 2517 HNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW----SKPVK-- 2570
               +N M PM   GL        +R  R     L + +  F+ +P  +W     K +K  
Sbjct: 3933 RQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKG 3992

Query: 2571 ------------------------------------------GHSKAPLNETGEVVNEKA 2588
                                                      GH KAP       V   +
Sbjct: 3993 GSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGS 4052

Query: 2589 KTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 2644
            K H +  ++   G            LS E  V  L+ +ATD N+L + + GW P+M
Sbjct: 4053 KDHNIRAQEPESG------------LSEETQVKCLMDQATDPNILGRTWEGWEPWM 4096


>gi|4507691 transformation/transcription domain-associated protein
            [Homo sapiens]
          Length = 3830

 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 87/376 (23%), Positives = 162/376 (43%), Gaps = 19/376 (5%)

Query: 2285 PFPGHWAY-IAGFDDMVEILASLQKP-KKISLKGSDGKFY---IMMCKPKDDLRKDCRLM 2339
            P P H+   IA F   VEI+       +++ ++G +GK Y   +M      + R++ R++
Sbjct: 3458 PKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVL 3517

Query: 2340 EFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGV 2399
            +   L+N CL K  E+ +R L      V+ ++ +  ++E   ++  L  I  +   +KG+
Sbjct: 3518 QLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGI 3577

Query: 2400 --------YMTGKELRQCMLPKSA--ALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTS 2449
                    Y       Q    +++   L + LK  +  ++PR   +  EW L TFP+ T 
Sbjct: 3578 EHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRS--MLKEWALHTFPNATD 3635

Query: 2450 WYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGE-TFEVP 2508
            +++ R  +    A++    ++L L   + E +     TG+     F    N      +  
Sbjct: 3636 YWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDAN 3695

Query: 2509 EIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKP 2568
              VPFRLT N+   +  +G  G    +     R        +  +LKT L D ++ W K 
Sbjct: 3696 RPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKK 3755

Query: 2569 VKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEAT 2628
             +  + +PL+  G+  N  ++  ++ + Q+    I TR          E  V+ L+  A 
Sbjct: 3756 TQEDTSSPLSAAGQPENMDSQ-QLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAAN 3814

Query: 2629 DENLLCQMYLGWTPYM 2644
              + LC+M   W P++
Sbjct: 3815 SLDNLCRMDPAWHPWL 3830


>gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapiens]
          Length = 887

 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 59/239 (24%), Positives = 102/239 (42%), Gaps = 51/239 (21%)

Query: 2302 ILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELH 2361
            +  S   P ++  K  DG  Y ++ K  DDLR+D  +++  SL++K LRK+      +L 
Sbjct: 611  LFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKE----NLDLK 666

Query: 2362 IRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKL 2421
            +  Y V+  + + G ++++ +     P+   L  E  +                      
Sbjct: 667  LTPYKVLATSTKHGFMQFIQSV----PVAEVLDTEGSIQ--------------------- 701

Query: 2422 KVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSR--SAYCRSTAVMSMVGYILGLGDRHGE 2479
              FR++    + P              +  S+     Y +S A   ++ YILG+GDRH +
Sbjct: 702  NFFRKYAPSENGP--------------NGISAEVMDTYVKSCAGYCVITYILGVGDRHLD 747

Query: 2480 NILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGL--FRRAC 2536
            N+L  + TG+  H+DF  +  +      P   P +L   MV GMG   +E    FR+ C
Sbjct: 748  NLLL-TKTGKLFHIDFGYILGRDPK---PLPPPMKLNKEMVEGMGGTQSEQYQEFRKQC 802


>gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypeptide
            [Homo sapiens]
          Length = 1102

 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 52/234 (22%), Positives = 98/234 (41%), Gaps = 43/234 (18%)

Query: 2301 EILASLQKPKKISLKGSD-----GKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAES 2355
            +++AS +KP  +  K +D      +   ++ K  DDLR+D  +++    I + +    E+
Sbjct: 802  KVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQ----ILRIMESIWET 857

Query: 2356 RRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSA 2415
               +L +  Y  I   D+ G+IE V +                   T  +++Q  +  + 
Sbjct: 858  ESLDLCLLPYGCISTGDKIGMIEIVKDAT-----------------TIAKIQQSTVGNTG 900

Query: 2416 ALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGD 2475
            A  ++              + + W     P    + ++   +  S A   +  ++LG+GD
Sbjct: 901  AFKDE--------------VLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGD 946

Query: 2476 RHGENILFDSLTGECVHVDFNCLFNKGETF--EVPEIVPFRLTHNMVNGMGPMG 2527
            RH +NI+    TG   H+DF  +    ++F     E VPF LT + +  MG  G
Sbjct: 947  RHNDNIMITE-TGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSG 999


>gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo
            sapiens]
          Length = 1070

 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 92/225 (40%), Gaps = 42/225 (18%)

Query: 2327 KPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGL 2386
            K  DDLR+D   ++   L++  L K+A     +L +  Y  +   D  G+IE V+ +  +
Sbjct: 805  KNGDDLRQDMLTLQMLRLMD-LLWKEAGL---DLRMLPYGCLATGDRSGLIEVVSTSETI 860

Query: 2387 RPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPD 2446
              I              K+     L +  +  +  +   EF L                 
Sbjct: 861  ADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTL----------------- 903

Query: 2447 PTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDF-NCLFNKGETF 2505
                  S + YC       +  Y+LG+GDRH +NI+    TG+  H+DF + L N    F
Sbjct: 904  ------SCAGYC-------VASYVLGIGDRHSDNIMVKK-TGQLFHIDFGHILGNFKSKF 949

Query: 2506 EVP-EIVPFRLTHNMVN--GMGPMGTE---GLFRRACEVTMRLMR 2544
             +  E VPF LT++ ++    G  G     G FR+ CE    ++R
Sbjct: 950  GIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILR 994


>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
            [Homo sapiens]
          Length = 1686

 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 61/264 (23%), Positives = 104/264 (39%), Gaps = 45/264 (17%)

Query: 2309 PKKISLKGSD--GKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYA 2366
            P K+++  +D  G+   +M K  +DLR+D   ++   +++K   K+      +L +  + 
Sbjct: 1118 PLKVTMVNADPMGEEINVMFKVGEDLRQDMLALQMIKIMDKIWLKEG----LDLRMVIFK 1173

Query: 2367 VIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFRE 2426
             +    + G++E V  +  LR    K+  E GV  + K+       K  A          
Sbjct: 1174 CLSTGRDRGMVELVPASDTLR----KIQVEYGVTGSFKD-------KPLA---------- 1212

Query: 2427 FLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSL 2486
                       EW  +  P    +  +   +  S A   +  Y+LG+ DRH +NI+  S 
Sbjct: 1213 -----------EWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRS- 1260

Query: 2487 TGECVHVDFNCLFNKGETFE--VPEIVPFRLTHNMV----NGMGPMGTEGLFRRACEVTM 2540
            TG   H+DF       + F     +  PF LT +M      G  P     LF   C    
Sbjct: 1261 TGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAY 1320

Query: 2541 RLMRDQREPLMSVLKTFLHDPLVE 2564
             L+R Q    +++L   +   L E
Sbjct: 1321 NLIRKQTNLFLNLLSLMIPSGLPE 1344


>gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo
            sapiens]
          Length = 1044

 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 58/236 (24%), Positives = 102/236 (43%), Gaps = 43/236 (18%)

Query: 2316 GSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECG 2375
            GS G   I+  K  DDLR+D   ++   L++   +++      +L +  Y  +P  D  G
Sbjct: 769  GSGGSVGIIF-KNGDDLRQDMLTLQMIQLMDVLWKQEG----LDLRMTPYGCLPTGDRTG 823

Query: 2376 IIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPI 2435
            +IE V  +  +  I               +L +  +  +AA ++   +   +L  ++P  
Sbjct: 824  LIEVVLRSDTIANI---------------QLNKSNMAATAAFNKDALL--NWLKSKNPGE 866

Query: 2436 FHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDF 2495
              +  +  F        S + YC +T       Y+LG+GDRH +NI+    +G+  H+DF
Sbjct: 867  ALDRAIEEFT------LSCAGYCVAT-------YVLGIGDRHSDNIMIRE-SGQLFHIDF 912

Query: 2496 NCLFNKGET-FEV-PEIVPFRLTHNMVNGMGPMGTEG-----LFRRACEVTMRLMR 2544
                   +T F +  E VPF LT++ V+ +    T        FR  CE    ++R
Sbjct: 913  GHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILR 968


>gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo
            sapiens]
          Length = 828

 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 67/283 (23%), Positives = 120/283 (42%), Gaps = 55/283 (19%)

Query: 2324 MMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNT 2383
            ++ K  DDLR++  L+ F  L  K L+   E  R  L I+ Y ++ ++ + G+IE V N 
Sbjct: 573  VIVKCGDDLRQE--LLAFQVL--KQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNA 628

Query: 2384 AGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRT 2443
              +  +                       K + LS       ++ L  H     E FL  
Sbjct: 629  VSIHQV----------------------KKQSQLS-----LLDYFLQEHGSYTTEAFL-- 659

Query: 2444 FPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGE 2503
                    S++  + +S A   +V Y+L + DRH  NIL D+  G  +H+DF  + +   
Sbjct: 660  --------SAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDA-EGHIIHIDFGFILSSSP 710

Query: 2504 TFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLH-DPL 2562
                 E   F+LT   V+ MG  G +G      ++ M         L  ++    H D +
Sbjct: 711  RNLGFETSAFKLTTEFVDVMG--GLDGDMFNYYKMLM---------LQGLIAARKHMDKV 759

Query: 2563 VEWSKPVKGHSKAP-LNETGEVVNEKAKTHVLDIEQRLQGVIK 2604
            V+  + ++  S+ P  + +  + N K + H+   E++LQ +++
Sbjct: 760  VQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVE 802


>gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 [Homo
            sapiens]
          Length = 854

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 3/90 (3%)

Query: 2437 HEWFLRTFPDPTS--WYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVD 2494
            +++F R + D ++  +  +R  + RS A  S++ ++L + DRH  NI+ D   G  +H+D
Sbjct: 669  YDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDK-KGHIIHID 727

Query: 2495 FNCLFNKGETFEVPEIVPFRLTHNMVNGMG 2524
            F  +F       +      +LT  MV  MG
Sbjct: 728  FGFMFESSPGGNLGWEPDIKLTDEMVMIMG 757


>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
            [Homo sapiens]
          Length = 2044

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 3/90 (3%)

Query: 2437 HEWFLRTFPDPTS--WYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVD 2494
            +++F R + D ++  +  +R  + RS A  S++ ++L + DRH  NI+ D   G  +H+D
Sbjct: 1859 YDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDK-KGHIIHID 1917

Query: 2495 FNCLFNKGETFEVPEIVPFRLTHNMVNGMG 2524
            F  +F       +      +LT  MV  MG
Sbjct: 1918 FGFMFESSPGGNLGWEPDIKLTDEMVMIMG 1947


>gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide
            [Homo sapiens]
          Length = 1445

 Score = 43.1 bits (100), Expect = 0.004
 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%)

Query: 2293 IAGFD-DMVEILASLQKPKKISLKGSD--GKFYIMMCKPKDDLRKDCRLMEFNSLINKCL 2349
            I G D D      S   P KI+   ++  GK   ++ K  DDLR+D  +++   +++   
Sbjct: 884  IKGIDHDACSYFTSNALPLKITFINANPMGKNISIIFKAGDDLRQDMLVLQLIQVMDNIW 943

Query: 2350 RKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC 2409
             ++      ++ +  Y  +    + G+++ V +       L K+++  G+    KE    
Sbjct: 944  LQEG----LDMQMIIYRCLSTGKDQGLVQMVPDAV----TLAKIHRHSGLIGPLKENT-- 993

Query: 2410 MLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGY 2469
                         + + F    H    +E  LR F      + S + +C       +V +
Sbjct: 994  -------------IKKWFSQHNHLKADYEKALRNF------FYSCAGWC-------VVTF 1027

Query: 2470 ILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFE--VPEIVPFRLTHNM-----VNG 2522
            ILG+ DRH +NI+  + +G   H+DF       +TF     +  PF  T  M       G
Sbjct: 1028 ILGVCDRHNDNIML-TKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGG 1086

Query: 2523 MGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWS 2566
              P   +      C     ++R   + L+++L+  L+  L E S
Sbjct: 1087 KNPQHFQDFVELCCR-AYNIIRKHSQLLLNLLEMMLYAGLPELS 1129


>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
            [Homo sapiens]
          Length = 1068

 Score = 42.0 bits (97), Expect = 0.008
 Identities = 48/196 (24%), Positives = 82/196 (41%), Gaps = 38/196 (19%)

Query: 2327 KPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGL 2386
            K  DDLR+D   ++    I + +    +++  +L +  Y  + + D  G+IE V N+  +
Sbjct: 802  KNGDDLRQDMLTLQ----IIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTI 857

Query: 2387 RPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPD 2446
              I                  QC      AL        ++L  ++    ++  +  F  
Sbjct: 858  MQI------------------QCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFT- 898

Query: 2447 PTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDF-NCLFNKGETF 2505
                  S + YC +T       +ILG+GDRH  NI+     G+  H+DF + L +K + F
Sbjct: 899  -----RSCAGYCVAT-------FILGIGDRHNSNIMVKD-DGQLFHIDFGHFLDHKKKKF 945

Query: 2506 EVP-EIVPFRLTHNMV 2520
                E VPF LT + +
Sbjct: 946  GYKRERVPFVLTQDFL 961


>gi|239757646 PREDICTED: similar to phosphatidylinositol 4-kinase type
            3 alpha [Homo sapiens]
          Length = 286

 Score = 40.8 bits (94), Expect = 0.018
 Identities = 20/65 (30%), Positives = 38/65 (58%), Gaps = 3/65 (4%)

Query: 2437 HEWFLRTFPDPTS--WYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVD 2494
            +++F R + D ++  +  +R  + RS A  S++ ++L + DRH  NI+ D   G  +H+D
Sbjct: 123  YDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDK-KGHIIHID 181

Query: 2495 FNCLF 2499
            F  +F
Sbjct: 182  FGFMF 186


>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
            [Homo sapiens]
          Length = 1634

 Score = 38.1 bits (87), Expect = 0.12
 Identities = 50/221 (22%), Positives = 87/221 (39%), Gaps = 44/221 (19%)

Query: 2309 PKKISLKGSD--GKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYA 2366
            P K+S +  D  G+   ++ K  DDLR+D   ++   +++K   ++    R  +    + 
Sbjct: 1063 PLKLSFQNVDPLGENIRVIFKCGDDLRQDMLTLQMIRIMSKIWVQEGLDMRMVI----FR 1118

Query: 2367 VIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFRE 2426
                    G++E + N   LR    K+  E GV  TG                    F++
Sbjct: 1119 CFSTGRGRGMVEMIPNAETLR----KIQVEHGV--TGS-------------------FKD 1153

Query: 2427 FLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSL 2486
              L        +W  +  P    +  +   +  S A   +  Y+LG+ DRH +NI+  + 
Sbjct: 1154 RPLA-------DWLQKHNPGEDEYEKAVENFIYSCAGCCVATYVLGICDRHNDNIMLKT- 1205

Query: 2487 TGECVHVDFNCLFNKGETFE--VPEIVPFRLTHNM---VNG 2522
            TG   H+DF       + F     +  PF  T +M   +NG
Sbjct: 1206 TGHMFHIDFGRFLGHAQMFGNIKRDRAPFVFTSDMAYVING 1246


>gi|21361794 TIP120 protein [Homo sapiens]
          Length = 1230

 Score = 36.2 bits (82), Expect = 0.44
 Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 4/111 (3%)

Query: 1263 KIKAVLQEYRKETSESTDLQTTLQLSMKAIQH--ENVDVRIHALTSLKETLYKNQEKLIK 1320
            ++K+V+ E     SE      +  L   ++ +  E +   +  +TS  +  Y     L +
Sbjct: 856  ELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKE 915

Query: 1321 YATDSETV--EPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRL 1369
              + +  V  +P +  +  +LLK C+ A    R +  ECLG+L  IDP  L
Sbjct: 916  IISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETL 966


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score = 34.7 bits (78), Expect = 1.3
 Identities = 42/211 (19%), Positives = 88/211 (41%), Gaps = 28/211 (13%)

Query: 1597 QALKAEKCPHSKSNRNKVDSMVSTVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVM 1656
            Q ++AE+    K+  NK  S +  V + + Q+       + +   A+   +     R  +
Sbjct: 143  QRVRAEEREQIKTLNNKFASFIDKVRFLEQQNK------VLETKWALLQEQGSRTVRQNL 196

Query: 1657 H--FESFITEKKQNIQEHLGFLQKLYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGL 1714
               F+S+ +E ++ ++       +L A +     V     +R  +   K    E+E + L
Sbjct: 197  EPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVAL 256

Query: 1715 LRDATACYDRAIQLE------PDQIIHYHGVVKSMLG-----LGQLSTVITQVNGVHAN- 1762
             +D  A Y   ++LE      P++I   H V  + L      +G  S V++  N  + + 
Sbjct: 257  KKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDL 316

Query: 1763 -------RSEWTDELNTYRVEA-AWKLSQWD 1785
                   ++++ D  N  R EA +W  ++++
Sbjct: 317  DSIIAEVKAQYEDIANRSRAEAESWYQTKYE 347


>gi|4507947 tyrosyl-tRNA synthetase [Homo sapiens]
          Length = 528

 Score = 33.5 bits (75), Expect = 2.9
 Identities = 42/165 (25%), Positives = 75/165 (45%), Gaps = 15/165 (9%)

Query: 339 SDLLKAALCHL------LQYFLKFVPAGYESALQVRKVYVRNICKALLDVLGIEVD-AEY 391
           +D LKA  C +      L  +L  + A +E  L++R  Y  N+ KA+L+ +G+ ++  ++
Sbjct: 60  ADFLKAG-CEVTILFADLHAYLDNMKAPWE-LLELRVSYYENVIKAMLESIGVPLEKLKF 117

Query: 392 LLGPLYAALKMESMEIIEEIQCQTQQENLSSNSDGISP-KRRRLSSSLNPSKRAPKQTEE 450
           + G  Y   K  ++++       TQ ++  + ++ +   +   LS  L P  +A    EE
Sbjct: 118 IKGTDYQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQA--LDEE 175

Query: 451 IKHVDMNQKSILWSALKQKAESLQISLEYS---GLKNPVIEMLEG 492
              VD     I    +   AE    +L YS    L NP++  L G
Sbjct: 176 YLKVDAQFGGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTG 220


>gi|89886470 hypothetical protein LOC84960 [Homo sapiens]
          Length = 534

 Score = 32.7 bits (73), Expect = 4.9
 Identities = 48/235 (20%), Positives = 89/235 (37%), Gaps = 30/235 (12%)

Query: 276 LLKHLVEMDTDQLKLYEEPLSKLIKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLM 335
           LL HLV     +L+  +  L  L        ++   + E + L  ++ +L    E  ++ 
Sbjct: 109 LLIHLVRRRGQKLESMQLELDSL-------RSQPDASKEELRLLQIIRQLENNIEKTMIK 161

Query: 336 RLKSDLLKAALCHLLQYFLKFVPAGYESALQVRKVYVRNICKALLDVLGIEVDAEYLLGP 395
            + S  +      LL Y LK V AGY   L   +  V N C  L D+  +  DA  +   
Sbjct: 162 IITSQNIHLLYLDLLDY-LKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDE 220

Query: 396 LYAALKMESMEIIEEIQCQTQQENLSSNSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVD 455
           +   ++      IEE + +  + N          ++++L   ++  + + K       +D
Sbjct: 221 VKRNMRQREASFIEERRARENRLN----------QQKKLIDKIHTKETSEKYRRGQMDLD 270

Query: 456 MNQKSILWSALK-QKAESLQISLEYSGLKNPVIEMLEGIAVVLQLTALCTVHCSH 509
                +    LK ++ E+    +EY      V+E ++             V CSH
Sbjct: 271 FPSNLMSTETLKLRRKETSTAEMEYQSGVTAVVEKVKS-----------AVRCSH 314


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 32.3 bits (72), Expect = 6.4
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 11/85 (12%)

Query: 1136 MQLLSSSVGIEDKKMALNSLMSLMKLMGP-----------KHVSSVRVKMMTTLRTGLRF 1184
            +QLL+   G   K MA+NS M   +L+G            + +  V   +   LR  L  
Sbjct: 2076 VQLLAHLTGHTLKIMAMNSAMDTTELLGGFEQVDLIRPWRRLLEKVEGTVRALLRDSLLI 2135

Query: 1185 KDDFPELCCRAWDCFVRCLDHACLG 1209
              D  E+  RAW  F+      CLG
Sbjct: 2136 SADDAEVVLRAWSHFLLTYKPKCLG 2160


>gi|19913369 transducin beta-like 3 [Homo sapiens]
          Length = 808

 Score = 32.3 bits (72), Expect = 6.4
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 12/96 (12%)

Query: 871 LTTGDIG-----RAAKGDLV------PFALLHLLHCLLSKSASVSGAAYTEIRALV-AAK 918
           LT GD G      AA G  V      P     L HC L+ +A V   A  +   L+  A+
Sbjct: 263 LTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEAR 322

Query: 919 SVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPC 954
           S++LQ  F+ Y + +          S +    N+PC
Sbjct: 323 SLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPC 358


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,745,681
Number of Sequences: 37866
Number of extensions: 3967331
Number of successful extensions: 9556
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 9433
Number of HSP's gapped (non-prelim): 98
length of query: 2644
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2525
effective length of database: 13,741,464
effective search space: 34697196600
effective search space used: 34697196600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.