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Search of human proteins with 110556636
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
(1729 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens] 3510 0.0
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 86 4e-16
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 86 4e-16
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 86 4e-16
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 86 4e-16
gi|223633988 hypothetical protein LOC85379 [Homo sapiens] 81 8e-15
gi|163965366 nascent polypeptide-associated complex alpha subuni... 81 8e-15
gi|150170670 piccolo isoform 2 [Homo sapiens] 81 1e-14
gi|150378539 piccolo isoform 1 [Homo sapiens] 81 1e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 7e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 74 1e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 2e-12
gi|57864582 hornerin [Homo sapiens] 73 2e-12
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 72 4e-12
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 70 1e-11
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 70 1e-11
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 70 1e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 70 2e-11
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 67 2e-10
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 67 2e-10
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 65 4e-10
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 65 6e-10
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 65 7e-10
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 64 1e-09
gi|60097902 filaggrin [Homo sapiens] 62 4e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 62 4e-09
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 62 4e-09
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 62 4e-09
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 62 5e-09
gi|55750053 atrophin-1 [Homo sapiens] 62 5e-09
>gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
Length = 1729
Score = 3510 bits (9101), Expect = 0.0
Identities = 1729/1729 (100%), Positives = 1729/1729 (100%)
Query: 1 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL 60
MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL
Sbjct: 1 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL 60
Query: 61 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE 120
VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE
Sbjct: 61 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE 120
Query: 121 EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD 180
EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD
Sbjct: 121 EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD 180
Query: 181 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP 240
RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP
Sbjct: 181 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP 240
Query: 241 EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG 300
EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG
Sbjct: 241 EERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPG 300
Query: 301 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG 360
SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG
Sbjct: 301 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG 360
Query: 361 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP 420
APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP
Sbjct: 361 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP 420
Query: 421 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF 480
TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF
Sbjct: 421 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF 480
Query: 481 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS 540
PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS
Sbjct: 481 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS 540
Query: 541 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE 600
SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE
Sbjct: 541 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE 600
Query: 601 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ 660
SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ
Sbjct: 601 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ 660
Query: 661 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL 720
ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL
Sbjct: 661 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL 720
Query: 721 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ 780
LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ
Sbjct: 721 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQ 780
Query: 781 GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD 840
GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD
Sbjct: 781 GAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD 840
Query: 841 VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ 900
VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ
Sbjct: 841 VQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQ 900
Query: 901 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD 960
DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD
Sbjct: 901 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRD 960
Query: 961 YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG 1020
YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG
Sbjct: 961 YSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG 1020
Query: 1021 ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE 1080
ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE
Sbjct: 1021 ERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGE 1080
Query: 1081 MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS 1140
MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS
Sbjct: 1081 MGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPS 1140
Query: 1141 SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL 1200
SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL
Sbjct: 1141 SKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSL 1200
Query: 1201 RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW 1260
RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW
Sbjct: 1201 RDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDW 1260
Query: 1261 SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL 1320
SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL
Sbjct: 1261 SGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDL 1320
Query: 1321 EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH 1380
EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH
Sbjct: 1321 EVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRH 1380
Query: 1381 NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP 1440
NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP
Sbjct: 1381 NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP 1440
Query: 1441 GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPG 1500
GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPG
Sbjct: 1441 GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPG 1500
Query: 1501 RDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFI 1560
RDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFI
Sbjct: 1501 RDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFI 1560
Query: 1561 EDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPS 1620
EDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPS
Sbjct: 1561 EDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPS 1620
Query: 1621 SDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQK 1680
SDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQK
Sbjct: 1621 SDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQK 1680
Query: 1681 ESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV 1729
ESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV
Sbjct: 1681 ESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV 1729
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 85.5 bits (210), Expect = 4e-16
Identities = 162/698 (23%), Positives = 240/698 (34%), Gaps = 127/698 (18%)
Query: 2 KVSTLRESSAMASP---LPREMEEELVPTGSEPGDTRAKP----PVKPKPRALPAKPALP 54
K T + A+ +P P +E T EP T K P +P P + P P
Sbjct: 200 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 259
Query: 55 AKPSLLVPVGPRP--PRGPLAEL-----PSARKMNMLAGPQPYGGS-KRPLPFAPRPAVE 106
+P+ P P P+ P P+ K +P + K+P P P+
Sbjct: 260 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 319
Query: 107 ASTGGEATQETGKEEAGK-EEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL 165
+T E T T KE A +EP P TP AP +K PAP P E T E
Sbjct: 320 -TTPKEPTPTTPKEPAPTTKEPAPTTPKE--PAPTAPKK-PAPTTP-KEPAPTTPKEPAP 374
Query: 166 AKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGP 225
++P P P T + E T +
Sbjct: 375 TTTKEPSPTTPKEP------------------APTTTKSAPTTTKEPAPTTTKSAPTTPK 416
Query: 226 VKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGP 285
SP +E TP+E + + K + P + + P P PAP++
Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTP--------KKPAPTTPKEPA-PTTPKEPAPTTTK--K 465
Query: 286 ASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPD 345
+P P E + + P P K +P + L TPE P P TP + P+
Sbjct: 466 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPT-TPEELAPTTPE 520
Query: 346 EGSRHTPSPGLPAEGAPEAPRPSSP-PPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTF 404
E P+P P E AP P+ ++P P+ P + +P T+P+
Sbjct: 521 E-----PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPA 563
Query: 405 PSGGEEEA----KGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLAL 460
P+ +E A KG A PT+L + +P+ ++ LA + +
Sbjct: 564 PTTPKETAPTTPKGTA---PTTLKE--------PAPTTPKKPAPKELAPTTTKEPTSTTC 612
Query: 461 DRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSR 520
D+P PT P G P P T E A G + +
Sbjct: 613 DKPA----------------PTTPKGTAPTTPKEPAP---TTPKEPAPTTPKGTAPTTLK 653
Query: 521 EEGVSQQGQGAGS--APSGSGSSWVQGDDPSMSLTQKGDGESQPQFPA--VPLEPLPTTE 576
E + + A AP+ + D T K + P+ PA P +P PTT
Sbjct: 654 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 713
Query: 577 GTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFAD 636
TP + ++EP +SP +A P P + P P P
Sbjct: 714 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKEPGVPTTKTPA 771
Query: 637 APEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPE 674
A +P E T A+ +TT+ +DL R +PE
Sbjct: 772 ATKP--------EMTTTAKDKTTE-----RDL-RTTPE 795
Score = 52.0 bits (123), Expect = 5e-06
Identities = 131/645 (20%), Positives = 215/645 (33%), Gaps = 95/645 (14%)
Query: 98 PFAPRPAVEASTG-GEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERF 156
P PRP++ ++ + T T +E E T + + G + A
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK-------- 174
Query: 157 AATTVEEILAKMEQPRKEVLASPD-----RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDE 211
++E+ AK P +VLA P G LT + + P+ +TT P++
Sbjct: 175 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT-PKEPASTT-PKEP 232
Query: 212 DGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPW 271
+T+ S K PA + + T + P+ K + P + + P
Sbjct: 233 TPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPAPTT-------TKEPAPTTPKEPA-PT 281
Query: 272 IPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPC 331
PAP++ P +P PA + P P ++P + P + P
Sbjct: 282 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 341
Query: 332 PAV---------------TPSAPSAALPDEGSRHT---PSPGLPAEGAP----EAPRPSS 369
P TP P+ P E + T PSP P E AP AP +
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 401
Query: 370 PP-----------PEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHL 418
P P+ P + +P T+P+ T K A
Sbjct: 402 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA-- 459
Query: 419 RPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEW 478
PT+ + + +P+ +E + L +LA P E
Sbjct: 460 -PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP-------------EK 505
Query: 479 TFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGN-----LAVSSREEGVSQQGQGAGS 533
PT P L + P P+ E + A A N + +E + + A +
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565
Query: 534 APSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTT--EGTPGLPLQQAEERYE 591
P + + +G P+ T K + P+ PA P E PTT E T + A +
Sbjct: 566 TPKETAPTTPKGTAPT---TLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPK 621
Query: 592 SQEPLAGQESPLPLATREAALPILEPVLGQ-EQPAAPDQPCVLFADAPEPGQALPVEEEA 650
P +E P P +E A P + P +P P P + P +
Sbjct: 622 GTAPTTPKE-PAPTTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 675
Query: 651 VTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPS 695
T ++ A T ++ +P+ P P + + +PPP+
Sbjct: 676 PTSTTSD-KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 719
Score = 49.3 bits (116), Expect = 3e-05
Identities = 100/459 (21%), Positives = 147/459 (32%), Gaps = 71/459 (15%)
Query: 315 SQLLEAQTPEASQASPCPAVT-PSAPSAALPDEGSRHTP----------SPGLPAEGAPE 363
S++L TP+A + PA+T P P+ P E + TP +P P E AP
Sbjct: 191 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 250
Query: 364 APRPSSPPPEVLEPHSLDQPPATSPR---PLIEVGELLDLTRTFPSGGEEEA----KGDA 416
+ + P+ P + +P T+P+ P T++ P+ +E A K A
Sbjct: 251 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310
Query: 417 HLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSF 476
P E +P + P+ + + A +P
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK-EPAPTAPKKPA------------ 357
Query: 477 EWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPS 536
PT P P P+ E S A S+ AP+
Sbjct: 358 ----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-------APT 406
Query: 537 GSGSSWVQGDDPSMSLTQKGDGESQPQFPA--VPLEPLPTT--EGTPGLPLQQAEERYES 592
+ S+ +PS + T K + P+ PA P +P PTT E P P + A +
Sbjct: 407 TTKSAPTTPKEPSPTTT-KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
Query: 593 QEPLAGQESPLPLATREAA-------LPILEPVLGQEQPA--APDQPCVLFADAPEPGQA 643
P +E P P +E A P L P AP P L PE
Sbjct: 466 PAPTTPKE-PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524
Query: 644 LPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGA 703
EE A T +A E P P P+ + A P G
Sbjct: 525 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG------- 577
Query: 704 GAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSS 742
+P+T E +K E T +P+S
Sbjct: 578 -------TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 609
Score = 37.7 bits (86), Expect = 0.098
Identities = 72/389 (18%), Positives = 124/389 (31%), Gaps = 49/389 (12%)
Query: 307 PDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSA--------ALPD----EGSRHTPSP 354
PD S C + + +P P V A S PD + ++ + SP
Sbjct: 57 PDYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSP 116
Query: 355 GLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEE--- 411
+ P PRPS PP S + + +E E + + G+E+
Sbjct: 117 KITT-AKPINPRPSLPPNS---DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTS 172
Query: 412 AKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWS 471
AK + TS + VL P+ E A + + P
Sbjct: 173 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS------ 226
Query: 472 LSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGA 531
T P P+ + + P P +++A +++E + + A
Sbjct: 227 -------TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 279
Query: 532 GSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYE 591
+ +P+ + T+ + P P +P PTT P +
Sbjct: 280 PTTTK----------EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329
Query: 592 SQEPLAGQESPLPLATREAALPILE---PVLGQE-QPAAPDQPCVLFADAPEPGQALPVE 647
+EP + P P +E A + P +E P P +P P P +
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPK 386
Query: 648 EEAVTLARAETTQARTEAQDLCRASPEPP 676
E A T ++ T + A +++P P
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 85.5 bits (210), Expect = 4e-16
Identities = 162/698 (23%), Positives = 240/698 (34%), Gaps = 127/698 (18%)
Query: 2 KVSTLRESSAMASP---LPREMEEELVPTGSEPGDTRAKP----PVKPKPRALPAKPALP 54
K T + A+ +P P +E T EP T K P +P P + P P
Sbjct: 241 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 300
Query: 55 AKPSLLVPVGPRP--PRGPLAEL-----PSARKMNMLAGPQPYGGS-KRPLPFAPRPAVE 106
+P+ P P P+ P P+ K +P + K+P P P+
Sbjct: 301 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 360
Query: 107 ASTGGEATQETGKEEAGK-EEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL 165
+T E T T KE A +EP P TP AP +K PAP P E T E
Sbjct: 361 -TTPKEPTPTTPKEPAPTTKEPAPTTPKE--PAPTAPKK-PAPTTP-KEPAPTTPKEPAP 415
Query: 166 AKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGP 225
++P P P T + E T +
Sbjct: 416 TTTKEPSPTTPKEP------------------APTTTKSAPTTTKEPAPTTTKSAPTTPK 457
Query: 226 VKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGP 285
SP +E TP+E + + K + P + + P P PAP++
Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTP--------KKPAPTTPKEPA-PTTPKEPAPTTTK--K 506
Query: 286 ASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPD 345
+P P E + + P P K +P + L TPE P P TP + P+
Sbjct: 507 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPT-TPEELAPTTPE 561
Query: 346 EGSRHTPSPGLPAEGAPEAPRPSSP-PPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTF 404
E P+P P E AP P+ ++P P+ P + +P T+P+
Sbjct: 562 E-----PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPA 604
Query: 405 PSGGEEEA----KGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLAL 460
P+ +E A KG A PT+L + +P+ ++ LA + +
Sbjct: 605 PTTPKETAPTTPKGTA---PTTLKE--------PAPTTPKKPAPKELAPTTTKEPTSTTC 653
Query: 461 DRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSR 520
D+P PT P G P P T E A G + +
Sbjct: 654 DKPA----------------PTTPKGTAPTTPKEPAP---TTPKEPAPTTPKGTAPTTLK 694
Query: 521 EEGVSQQGQGAGS--APSGSGSSWVQGDDPSMSLTQKGDGESQPQFPA--VPLEPLPTTE 576
E + + A AP+ + D T K + P+ PA P +P PTT
Sbjct: 695 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 754
Query: 577 GTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFAD 636
TP + ++EP +SP +A P P + P P P
Sbjct: 755 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKEPGVPTTKTPA 812
Query: 637 APEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPE 674
A +P E T A+ +TT+ +DL R +PE
Sbjct: 813 ATKP--------EMTTTAKDKTTE-----RDL-RTTPE 836
Score = 52.0 bits (123), Expect = 5e-06
Identities = 131/645 (20%), Positives = 215/645 (33%), Gaps = 95/645 (14%)
Query: 98 PFAPRPAVEASTG-GEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERF 156
P PRP++ ++ + T T +E E T + + G + A
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK-------- 215
Query: 157 AATTVEEILAKMEQPRKEVLASPD-----RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDE 211
++E+ AK P +VLA P G LT + + P+ +TT P++
Sbjct: 216 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT-PKEPASTT-PKEP 273
Query: 212 DGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPW 271
+T+ S K PA + + T + P+ K + P + + P
Sbjct: 274 TPTTIK---SAPTTPKEPAPTTTKSAPTTPKEPAPTT-------TKEPAPTTPKEPA-PT 322
Query: 272 IPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPC 331
PAP++ P +P PA + P P ++P + P + P
Sbjct: 323 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 382
Query: 332 PAV---------------TPSAPSAALPDEGSRHT---PSPGLPAEGAP----EAPRPSS 369
P TP P+ P E + T PSP P E AP AP +
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 442
Query: 370 PP-----------PEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHL 418
P P+ P + +P T+P+ T K A
Sbjct: 443 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA-- 500
Query: 419 RPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEW 478
PT+ + + +P+ +E + L +LA P E
Sbjct: 501 -PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP-------------EK 546
Query: 479 TFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGN-----LAVSSREEGVSQQGQGAGS 533
PT P L + P P+ E + A A N + +E + + A +
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606
Query: 534 APSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTT--EGTPGLPLQQAEERYE 591
P + + +G P+ T K + P+ PA P E PTT E T + A +
Sbjct: 607 TPKETAPTTPKGTAPT---TLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPK 662
Query: 592 SQEPLAGQESPLPLATREAALPILEPVLGQ-EQPAAPDQPCVLFADAPEPGQALPVEEEA 650
P +E P P +E A P + P +P P P + P +
Sbjct: 663 GTAPTTPKE-PAPTTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 716
Query: 651 VTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPS 695
T ++ A T ++ +P+ P P + + +PPP+
Sbjct: 717 PTSTTSD-KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 760
Score = 49.3 bits (116), Expect = 3e-05
Identities = 100/459 (21%), Positives = 147/459 (32%), Gaps = 71/459 (15%)
Query: 315 SQLLEAQTPEASQASPCPAVT-PSAPSAALPDEGSRHTP----------SPGLPAEGAPE 363
S++L TP+A + PA+T P P+ P E + TP +P P E AP
Sbjct: 232 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 291
Query: 364 APRPSSPPPEVLEPHSLDQPPATSPR---PLIEVGELLDLTRTFPSGGEEEA----KGDA 416
+ + P+ P + +P T+P+ P T++ P+ +E A K A
Sbjct: 292 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351
Query: 417 HLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSF 476
P E +P + P+ + + A +P
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK-EPAPTAPKKPA------------ 398
Query: 477 EWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPS 536
PT P P P+ E S A S+ AP+
Sbjct: 399 ----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-------APT 447
Query: 537 GSGSSWVQGDDPSMSLTQKGDGESQPQFPA--VPLEPLPTT--EGTPGLPLQQAEERYES 592
+ S+ +PS + T K + P+ PA P +P PTT E P P + A +
Sbjct: 448 TTKSAPTTPKEPSPTTT-KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
Query: 593 QEPLAGQESPLPLATREAA-------LPILEPVLGQEQPA--APDQPCVLFADAPEPGQA 643
P +E P P +E A P L P AP P L PE
Sbjct: 507 PAPTTPKE-PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565
Query: 644 LPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGA 703
EE A T +A E P P P+ + A P G
Sbjct: 566 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG------- 618
Query: 704 GAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSS 742
+P+T E +K E T +P+S
Sbjct: 619 -------TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 650
Score = 37.7 bits (86), Expect = 0.098
Identities = 72/389 (18%), Positives = 124/389 (31%), Gaps = 49/389 (12%)
Query: 307 PDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSA--------ALPD----EGSRHTPSP 354
PD S C + + +P P V A S PD + ++ + SP
Sbjct: 98 PDYESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSP 157
Query: 355 GLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEE--- 411
+ P PRPS PP S + + +E E + + G+E+
Sbjct: 158 KITT-AKPINPRPSLPPNS---DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTS 213
Query: 412 AKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWS 471
AK + TS + VL P+ E A + + P
Sbjct: 214 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS------ 267
Query: 472 LSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGA 531
T P P+ + + P P +++A +++E + + A
Sbjct: 268 -------TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 320
Query: 532 GSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYE 591
+ +P+ + T+ + P P +P PTT P +
Sbjct: 321 PTTTK----------EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370
Query: 592 SQEPLAGQESPLPLATREAALPILE---PVLGQE-QPAAPDQPCVLFADAPEPGQALPVE 647
+EP + P P +E A + P +E P P +P P P +
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPK 427
Query: 648 EEAVTLARAETTQARTEAQDLCRASPEPP 676
E A T ++ T + A +++P P
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 85.5 bits (210), Expect = 4e-16
Identities = 162/698 (23%), Positives = 240/698 (34%), Gaps = 127/698 (18%)
Query: 2 KVSTLRESSAMASP---LPREMEEELVPTGSEPGDTRAKP----PVKPKPRALPAKPALP 54
K T + A+ +P P +E T EP T K P +P P + P P
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 352
Query: 55 AKPSLLVPVGPRP--PRGPLAEL-----PSARKMNMLAGPQPYGGS-KRPLPFAPRPAVE 106
+P+ P P P+ P P+ K +P + K+P P P+
Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412
Query: 107 ASTGGEATQETGKEEAGK-EEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL 165
+T E T T KE A +EP P TP AP +K PAP P E T E
Sbjct: 413 -TTPKEPTPTTPKEPAPTTKEPAPTTPKE--PAPTAPKK-PAPTTP-KEPAPTTPKEPAP 467
Query: 166 AKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGP 225
++P P P T + E T +
Sbjct: 468 TTTKEPSPTTPKEP------------------APTTTKSAPTTTKEPAPTTTKSAPTTPK 509
Query: 226 VKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGP 285
SP +E TP+E + + K + P + + P P PAP++
Sbjct: 510 EPSPTTTKEPAPTTPKEPAPTTP--------KKPAPTTPKEPA-PTTPKEPAPTTTK--K 558
Query: 286 ASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPD 345
+P P E + + P P K +P + L TPE P P TP + P+
Sbjct: 559 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPT-TPEELAPTTPE 613
Query: 346 EGSRHTPSPGLPAEGAPEAPRPSSP-PPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTF 404
E P+P P E AP P+ ++P P+ P + +P T+P+
Sbjct: 614 E-----PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPA 656
Query: 405 PSGGEEEA----KGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLAL 460
P+ +E A KG A PT+L + +P+ ++ LA + +
Sbjct: 657 PTTPKETAPTTPKGTA---PTTLKE--------PAPTTPKKPAPKELAPTTTKEPTSTTC 705
Query: 461 DRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSR 520
D+P PT P G P P T E A G + +
Sbjct: 706 DKPA----------------PTTPKGTAPTTPKEPAP---TTPKEPAPTTPKGTAPTTLK 746
Query: 521 EEGVSQQGQGAGS--APSGSGSSWVQGDDPSMSLTQKGDGESQPQFPA--VPLEPLPTTE 576
E + + A AP+ + D T K + P+ PA P +P PTT
Sbjct: 747 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 806
Query: 577 GTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFAD 636
TP + ++EP +SP +A P P + P P P
Sbjct: 807 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKEPGVPTTKTPA 864
Query: 637 APEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPE 674
A +P E T A+ +TT+ +DL R +PE
Sbjct: 865 ATKP--------EMTTTAKDKTTE-----RDL-RTTPE 888
Score = 53.9 bits (128), Expect = 1e-06
Identities = 147/728 (20%), Positives = 245/728 (33%), Gaps = 105/728 (14%)
Query: 1 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL 60
+KV +++ P P+ + +G + GD + P + K + K +
Sbjct: 157 LKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQH--NKVSTSPKITTA 214
Query: 61 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE 120
P+ PRP P ++ ++++ ++ + +K E +T + T GKE
Sbjct: 215 KPINPRPSLPPNSD--TSKETSLTVNKETTVETK-----------ETTTTNKQTSTDGKE 261
Query: 121 E--AGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLAS 178
+ + KE A+ AP K A P +E TT L ++P
Sbjct: 262 KTTSAKETQSIEKTSAKDLAP--TSKVLAKPTPKAE---TTTKGPALTTPKEPTPTTPKE 316
Query: 179 PDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSK 238
P T P T + E T + +P +E
Sbjct: 317 PASTTPKEPT----------PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 239 TPEERSLPSDLAFNGDLAKAASSELPADI---SKPWIPSSPAPSSENGGPASPGLPAEAS 295
TP+E + +++ PA S P P PAP++ +P P E +
Sbjct: 367 TPKEPA-------------PTTTKEPAPTTTKSAPTTPKEPAPTTPK--KPAPTTPKEPA 411
Query: 296 GSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPC-PA-VTPSAPSAALPDEGSRHT-- 351
+ P P P + +P + E + +P PA TP P+ P E + T
Sbjct: 412 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 471
Query: 352 -PSPGLPAEGAP----EAPRPSSPP-----------PEVLEPHSLDQPPATSPRPLIEVG 395
PSP P E AP AP + P P+ P + +P T+P+
Sbjct: 472 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 531
Query: 396 ELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQG 455
T K A PT+ + + +P+ +E + L
Sbjct: 532 PKKPAPTTPKEPAPTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 588
Query: 456 SQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGN- 514
+LA P E PT P L + P P+ E + A A N
Sbjct: 589 EKLAPTTP-------------EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 635
Query: 515 ----LAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLE 570
+ +E + + A + P + + +G P+ T K + P+ PA P E
Sbjct: 636 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT---TLKEPAPTTPKKPA-PKE 691
Query: 571 PLPTT--EGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQ-EQPAAP 627
PTT E T + A + P +E P P +E A P + P
Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPA-----PTTPKGTAPTTL 745
Query: 628 DQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDD 687
+P P P + P + T ++ A T ++ +P+ P P + +
Sbjct: 746 KEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPTTPKKPAPT 804
Query: 688 LLASPPPS 695
+PPP+
Sbjct: 805 TPETPPPT 812
Score = 49.3 bits (116), Expect = 3e-05
Identities = 100/459 (21%), Positives = 147/459 (32%), Gaps = 71/459 (15%)
Query: 315 SQLLEAQTPEASQASPCPAVT-PSAPSAALPDEGSRHTP----------SPGLPAEGAPE 363
S++L TP+A + PA+T P P+ P E + TP +P P E AP
Sbjct: 284 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 343
Query: 364 APRPSSPPPEVLEPHSLDQPPATSPR---PLIEVGELLDLTRTFPSGGEEEA----KGDA 416
+ + P+ P + +P T+P+ P T++ P+ +E A K A
Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 417 HLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSF 476
P E +P + P+ + + A +P
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK-EPAPTAPKKPA------------ 450
Query: 477 EWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPS 536
PT P P P+ E S A S+ AP+
Sbjct: 451 ----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-------APT 499
Query: 537 GSGSSWVQGDDPSMSLTQKGDGESQPQFPA--VPLEPLPTT--EGTPGLPLQQAEERYES 592
+ S+ +PS + T K + P+ PA P +P PTT E P P + A +
Sbjct: 500 TTKSAPTTPKEPSPTTT-KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
Query: 593 QEPLAGQESPLPLATREAA-------LPILEPVLGQEQPA--APDQPCVLFADAPEPGQA 643
P +E P P +E A P L P AP P L PE
Sbjct: 559 PAPTTPKE-PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617
Query: 644 LPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGA 703
EE A T +A E P P P+ + A P G
Sbjct: 618 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG------- 670
Query: 704 GAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSS 742
+P+T E +K E T +P+S
Sbjct: 671 -------TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 702
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 85.5 bits (210), Expect = 4e-16
Identities = 162/698 (23%), Positives = 240/698 (34%), Gaps = 127/698 (18%)
Query: 2 KVSTLRESSAMASP---LPREMEEELVPTGSEPGDTRAKP----PVKPKPRALPAKPALP 54
K T + A+ +P P +E T EP T K P +P P + P P
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 393
Query: 55 AKPSLLVPVGPRP--PRGPLAEL-----PSARKMNMLAGPQPYGGS-KRPLPFAPRPAVE 106
+P+ P P P+ P P+ K +P + K+P P P+
Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453
Query: 107 ASTGGEATQETGKEEAGK-EEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL 165
+T E T T KE A +EP P TP AP +K PAP P E T E
Sbjct: 454 -TTPKEPTPTTPKEPAPTTKEPAPTTPKE--PAPTAPKK-PAPTTP-KEPAPTTPKEPAP 508
Query: 166 AKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGP 225
++P P P T + E T +
Sbjct: 509 TTTKEPSPTTPKEP------------------APTTTKSAPTTTKEPAPTTTKSAPTTPK 550
Query: 226 VKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGP 285
SP +E TP+E + + K + P + + P P PAP++
Sbjct: 551 EPSPTTTKEPAPTTPKEPAPTTP--------KKPAPTTPKEPA-PTTPKEPAPTTTK--K 599
Query: 286 ASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPD 345
+P P E + + P P K +P + L TPE P P TP + P+
Sbjct: 600 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPT-TPEELAPTTPE 654
Query: 346 EGSRHTPSPGLPAEGAPEAPRPSSP-PPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTF 404
E P+P P E AP P+ ++P P+ P + +P T+P+
Sbjct: 655 E-----PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPA 697
Query: 405 PSGGEEEA----KGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLAL 460
P+ +E A KG A PT+L + +P+ ++ LA + +
Sbjct: 698 PTTPKETAPTTPKGTA---PTTLKE--------PAPTTPKKPAPKELAPTTTKEPTSTTC 746
Query: 461 DRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSR 520
D+P PT P G P P T E A G + +
Sbjct: 747 DKPA----------------PTTPKGTAPTTPKEPAP---TTPKEPAPTTPKGTAPTTLK 787
Query: 521 EEGVSQQGQGAGS--APSGSGSSWVQGDDPSMSLTQKGDGESQPQFPA--VPLEPLPTTE 576
E + + A AP+ + D T K + P+ PA P +P PTT
Sbjct: 788 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 847
Query: 577 GTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFAD 636
TP + ++EP +SP +A P P + P P P
Sbjct: 848 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP--TPKALENSPKEPGVPTTKTPA 905
Query: 637 APEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPE 674
A +P E T A+ +TT+ +DL R +PE
Sbjct: 906 ATKP--------EMTTTAKDKTTE-----RDL-RTTPE 929
Score = 53.9 bits (128), Expect = 1e-06
Identities = 147/728 (20%), Positives = 245/728 (33%), Gaps = 105/728 (14%)
Query: 1 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL 60
+KV +++ P P+ + +G + GD + P + K + K +
Sbjct: 198 LKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQH--NKVSTSPKITTA 255
Query: 61 VPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKE 120
P+ PRP P ++ ++++ ++ + +K E +T + T GKE
Sbjct: 256 KPINPRPSLPPNSD--TSKETSLTVNKETTVETK-----------ETTTTNKQTSTDGKE 302
Query: 121 E--AGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLAS 178
+ + KE A+ AP K A P +E TT L ++P
Sbjct: 303 KTTSAKETQSIEKTSAKDLAP--TSKVLAKPTPKAE---TTTKGPALTTPKEPTPTTPKE 357
Query: 179 PDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSK 238
P T P T + E T + +P +E
Sbjct: 358 PASTTPKEPT----------PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 239 TPEERSLPSDLAFNGDLAKAASSELPADI---SKPWIPSSPAPSSENGGPASPGLPAEAS 295
TP+E + +++ PA S P P PAP++ +P P E +
Sbjct: 408 TPKEPA-------------PTTTKEPAPTTTKSAPTTPKEPAPTTPK--KPAPTTPKEPA 452
Query: 296 GSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPC-PA-VTPSAPSAALPDEGSRHT-- 351
+ P P P + +P + E + +P PA TP P+ P E + T
Sbjct: 453 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTK 512
Query: 352 -PSPGLPAEGAP----EAPRPSSPP-----------PEVLEPHSLDQPPATSPRPLIEVG 395
PSP P E AP AP + P P+ P + +P T+P+
Sbjct: 513 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 572
Query: 396 ELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQG 455
T K A PT+ + + +P+ +E + L
Sbjct: 573 PKKPAPTTPKEPAPTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 629
Query: 456 SQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGN- 514
+LA P E PT P L + P P+ E + A A N
Sbjct: 630 EKLAPTTP-------------EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 676
Query: 515 ----LAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLE 570
+ +E + + A + P + + +G P+ T K + P+ PA P E
Sbjct: 677 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT---TLKEPAPTTPKKPA-PKE 732
Query: 571 PLPTT--EGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQ-EQPAAP 627
PTT E T + A + P +E P P +E A P + P
Sbjct: 733 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE-PAPTTPKEPA-----PTTPKGTAPTTL 786
Query: 628 DQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDD 687
+P P P + P + T ++ A T ++ +P+ P P + +
Sbjct: 787 KEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPTTPKKPAPT 845
Query: 688 LLASPPPS 695
+PPP+
Sbjct: 846 TPETPPPT 853
Score = 49.3 bits (116), Expect = 3e-05
Identities = 100/459 (21%), Positives = 147/459 (32%), Gaps = 71/459 (15%)
Query: 315 SQLLEAQTPEASQASPCPAVT-PSAPSAALPDEGSRHTP----------SPGLPAEGAPE 363
S++L TP+A + PA+T P P+ P E + TP +P P E AP
Sbjct: 325 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 384
Query: 364 APRPSSPPPEVLEPHSLDQPPATSPR---PLIEVGELLDLTRTFPSGGEEEA----KGDA 416
+ + P+ P + +P T+P+ P T++ P+ +E A K A
Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 417 HLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSF 476
P E +P + P+ + + A +P
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK-EPAPTAPKKPA------------ 491
Query: 477 EWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPS 536
PT P P P+ E S A S+ AP+
Sbjct: 492 ----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-------APT 540
Query: 537 GSGSSWVQGDDPSMSLTQKGDGESQPQFPA--VPLEPLPTT--EGTPGLPLQQAEERYES 592
+ S+ +PS + T K + P+ PA P +P PTT E P P + A +
Sbjct: 541 TTKSAPTTPKEPSPTTT-KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Query: 593 QEPLAGQESPLPLATREAA-------LPILEPVLGQEQPA--APDQPCVLFADAPEPGQA 643
P +E P P +E A P L P AP P L PE
Sbjct: 600 PAPTTPKE-PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658
Query: 644 LPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGA 703
EE A T +A E P P P+ + A P G
Sbjct: 659 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG------- 711
Query: 704 GAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSS 742
+P+T E +K E T +P+S
Sbjct: 712 -------TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTS 743
>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
Length = 1806
Score = 81.3 bits (199), Expect = 8e-15
Identities = 75/247 (30%), Positives = 109/247 (44%), Gaps = 30/247 (12%)
Query: 1501 RDSPPSWRPQPDGEASQTE--------DVDGTWGSSAARWSDQGPAQTSRRPSQGPPARS 1552
R PPS R +SQTE D S++ S T PP
Sbjct: 1564 RKQPPSSRLS--SLSSQTEPTSAGDQYDCSRDQRSTSVDHSSTDLESTDGMEGPPPPDAC 1621
Query: 1553 PSQ---DFSFIEDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAAD-------- 1601
P + DFSFI+ T +LDS+ ++R L ++ RAP+ SE+
Sbjct: 1622 PEKRVDDFSFIDQTSVLDSSALKTRVQLSKRSRRRAPISHSLRRSRFSESESRSPLEDET 1681
Query: 1602 SDAHLFQDSTEPRASRVPSSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLR 1661
+ +F+DSTE ++ R SDE EE S+ R + + ++ FPG+ P+ LKA+L
Sbjct: 1682 DNTWMFKDSTEEKSPRKEESDE---EETASKAERTPV-SHPQRMPAFPGMDPAVLKAQLH 1737
Query: 1662 PRNRSAEEGELAESKSSQKESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQA 1721
R GE S + Q +S KS PG+ LP +K S+ SP WL+
Sbjct: 1738 KRPEVDSPGE-TPSWAPQPKS----PKSPFQPGVLGSRVLPSSMDKDERSDEPSPQWLKE 1792
Query: 1722 LKLKKKK 1728
LK KK++
Sbjct: 1793 LKSKKRQ 1799
Score = 36.6 bits (83), Expect = 0.22
Identities = 103/433 (23%), Positives = 158/433 (36%), Gaps = 60/433 (13%)
Query: 321 QTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSL 380
Q EAS A P + +P + +R P P L AP+P S +V P
Sbjct: 35 QAGEASGAPPARILEAKSPLRS----PARLLPLPRL-------APKPFSKEQDVKSPVPS 83
Query: 381 DQPPATSPRP---LIEVGELLDLTRTFPS-GGEEEAKGDAHLRPTSLVQRRFSEGVLQSP 436
+P +T P P L E DL P G+E G+ + L F++ V P
Sbjct: 84 LRPSSTGPSPSGGLSEEPAAKDLDNRMPGLVGQEVGSGEGPRTSSPL----FNKAVFLRP 139
Query: 437 SQ------DQEKLGGSLA-ALPQG-QGSQLAL--DRPFGAESNWSLSQSFEWTFPTRPSG 486
S + K G +L A+ +G + ++L + RP A +Q T P R +
Sbjct: 140 SSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQKPAGTLP-RSAP 198
Query: 487 LGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGD 546
L D+ PP P EA + ++A ++ ++R V + + S + +Q
Sbjct: 199 LS---QDTKPPVPQEEAGQDHPPSKASSVEDTARPL-VEPRPRLKRRPVSAIFTESIQPQ 254
Query: 547 DPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLA 606
P G G + P P T P R+E++E L L
Sbjct: 255 KP-------GPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTARFENKEAL------LRKV 301
Query: 607 TREAALPILEPVLGQEQPAAP---DQPCVLFADAPEPGQALPVEEEAVTL-ARAETTQAR 662
E + P + G E+P A D+ C++ A+AP L E A + R E ++
Sbjct: 302 ADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAKKIRERKEKMLSK 361
Query: 663 TE---AQDLCRASPEPPGPESSSRWLDDLLASPPP----SGGGARRGAGAELKDTQSPST 715
E + L S S W + P P R G G EL + +S
Sbjct: 362 PEMGSPRALVGGSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSPRLGRGLELAEVKSRVA 421
Query: 716 CSEGLLG--WSQK 726
E G W+ +
Sbjct: 422 DGEAAAGGEWASR 434
Score = 31.6 bits (70), Expect = 7.0
Identities = 88/411 (21%), Positives = 132/411 (32%), Gaps = 59/411 (14%)
Query: 84 LAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETG----KEEAGKEEPPPLTPPARCAAP 139
++G +P +K LP +PA +Q+T +EEAG++ PP A
Sbjct: 171 VSGSRPEVAAKPALP-TQKPAGTLPRSAPLSQDTKPPVPQEEAGQDHPPSKASSVEDTAR 229
Query: 140 GGVRKAPA-PFRPASERF------------AATTVEEILAK------MEQPRKEVLASPD 180
V P RP S F AA TV ++ + +PR +
Sbjct: 230 PLVEPRPRLKRRPVSAIFTESIQPQKPGPGAAATVGKVPPTPPEKTWVRKPRPLSMDLTA 289
Query: 181 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGW--SQEGPVKSP--------A 230
R GP R S L R E P+ P
Sbjct: 290 RFENKEALLRKVADEGSGPTAGDMAGLERPRAASKLDRDCLVKAEAPLHDPDLDFLEVAK 349
Query: 231 ECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPW------------IPSSPAP 278
+ RE K + + S A G +S P++ PW SP+P
Sbjct: 350 KIRERKEKMLSKPEMGSPRALVG----GSSGVTPSNDQSPWEEKAKLDPEPEKAAESPSP 405
Query: 279 SSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSA 338
G + A G C S E T + S P TP++
Sbjct: 406 RLGRGLELAEVKSRVADGEAAAGGEWASRRSVRKCISLFREDSTLALAVGSESPLATPAS 465
Query: 339 PSAA-LPDEG--SRHTPSPGLPAEGAPEAP----RPSSPPPEVLEPHSLDQPPATSPRPL 391
PSAA P++G S G AE + P R P + L A+S
Sbjct: 466 PSAAPEPEKGVVSVQERIRGWTAESSEAKPEVRRRTFQARPLSADLTKLFSSSASSNE-- 523
Query: 392 IEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEK 442
++ + +L+ FP E+ K L + + + G L+ S+ E+
Sbjct: 524 VKYEKSAELSGEFPKEPREKQKEGHSLDGACIPRSPWKPGTLRDKSRQTEQ 574
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 81.3 bits (199), Expect = 8e-15
Identities = 165/763 (21%), Positives = 251/763 (32%), Gaps = 115/763 (15%)
Query: 8 ESSAMASPLPREMEEELVPTGSEPGDTRAKPPVK-----------PKPRALPAKPALPAK 56
+ S A+P P+ T P + A P+ P P+ PA P+L
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 57 PSLLVPVGPRPPRGPLAELPSARKMNMLA-GPQPYGGSKRP----LPFAPRPAVEASTGG 111
P+ P P GP P M A P P GG P P P + GG
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139
Query: 112 EATQETGKEEAGKEEPPPLTPPA-----RCAAPGGVRKAPAPFRPASERFAATT----VE 162
AT G P TPP+ P G PA P+ + AT
Sbjct: 1140 LAT----PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 163 EILAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQ 222
A K LA+P G+ T ++ P+ T +P+ G+ +
Sbjct: 1196 TTPAATPPSPKGGLATPSPK-GAPTT---PAATPPSPKGGLATPSPK---GAPTTPAATP 1248
Query: 223 EGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKA--ASSELPADISKPWIPSSPAPSS 280
P PA + + TP + PS G LA + PA ++ P PA S
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPS---LKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305
Query: 281 ENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASP-CPAVTPSAP 339
G P P + PG+ PP K +P A TP + + +P PA TPS+
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGT----PPPKGAPTP----PAVTPPSPKGTPTLPATTPSSK 1357
Query: 340 SA-ALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELL 398
P TP P+ A P SP P P TSP + +
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP--TSPAVIPLSPKKA 1415
Query: 399 DLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQL 458
T G +KGD L P ++ + ++P+ K GG +G +
Sbjct: 1416 PATPVTREGAATPSKGD--LTPPAVT----PVSLKKAPATSAPK-GGPATPSSKGDPTLP 1468
Query: 459 ALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVS 518
A+ P E P+ V SP +P T A A A + S
Sbjct: 1469 AVTPPSPKEP---------------PAPKQVATSSSPKKAPATPAPMGAPTLPA-VIPSS 1512
Query: 519 SREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAV-PLEPLPTTEG 577
+E + + AP+ + L++K P+ + P +P+ +
Sbjct: 1513 PKEVPATPSSRRDPIAPTAT------------LLSKKTPATLAPKEALIPPAMTVPSPKK 1560
Query: 578 TPGLPLQQAEERYESQEPLAGQESPLPLATREAALP---ILEPVLGQEQPAAPDQPCVLF 634
TP +P + S + + + P + A P ++ P + P P +
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Query: 635 ADAPEPGQALPVE--------------EEAVTLARAETTQARTEAQDLCRASPEPPGPES 680
+PE G A P +++ T + T + + P GP +
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680
Query: 681 SSRWLDDLLASPPPSG-----GGARRGAGAELKDTQSPSTCSE 718
L ++L +P P R+G + SP C +
Sbjct: 1681 ----LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
Score = 72.0 bits (175), Expect = 5e-12
Identities = 180/773 (23%), Positives = 253/773 (32%), Gaps = 175/773 (22%)
Query: 24 LVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNM 83
LVPT SE PV P P+ A A + P P P P +K++
Sbjct: 700 LVPTASE------NCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDG 753
Query: 84 LAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVR 143
++ + + P+ +P+ +G AT + LT A +P GV
Sbjct: 754 IS----HTSALAPVASSPKECPTEDSGASATASS---------KGTLTYLADSPSPLGVS 800
Query: 144 KAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYG 203
+P RP +++ +A + + + P V AS L + L+F S+ P T
Sbjct: 801 VSPQTKRPPTKKGSAGP-DTPIGNLSSPVSPVEAS--FLPENSLSFQ---GSKDSPATTH 854
Query: 204 TTTAPRDEDGST--LFRGWSQEGPVKSPAECR----------EEHSKTPEERSLPSDLAF 251
+ T P + T S +G P E +E TP + P+
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
Query: 252 NGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLH----PP 307
+ KA ++ P I P+SP+P G P P + GP +P PP
Sbjct: 915 SSSPKKARATPAPKGI-----PASPSPK---GAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 308 DKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPD-EGSRHTPSP-GLPAEGAPEAP 365
+ P +P+ A+P P P+ P+A P +G TPSP G P A P
Sbjct: 967 AATPP---------SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017
Query: 366 RPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQ 425
P P P PPA +P
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATP------------------------------------- 1040
Query: 426 RRFSEGVLQSPSQDQEKLGGSLAALPQGQGS----QLALDRPFGAESNWSLSQSFEWTFP 481
SP GS AA P +G+ L P G + SL +
Sbjct: 1041 --------PSPK-------GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 482 TRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSS 541
T PS G SP +P+ A A + G LA +GA + P+ + S
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPA--ATPPSPKGGLATPPH--------KGAPTTPAATPPS 1135
Query: 542 WVQGDDPSMSLTQKGDGESQPQFPAVPLEPL--PTTEGTPGLPLQQAEERYESQEPLAGQ 599
G + KG + P P L P +G P P P G
Sbjct: 1136 PKGG---LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA------TPPSPKGGL 1186
Query: 600 ESPLP--LATREAALPILEPVLGQEQPAAPDQPCVLFADAPEP--GQALPVEEEAVTLAR 655
+P P T AA P P G P+ P A P P G A P +
Sbjct: 1187 ATPSPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK------G 1239
Query: 656 AETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPST 715
A TT A T PP P+ A+PPP GA +P +
Sbjct: 1240 APTTPAAT-----------PPSPKGGP-------ATPPPK--------GAPTPPAATPPS 1273
Query: 716 CSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPG 768
GL K + +T P P +S +GA SP+G PG
Sbjct: 1274 LKGGLATPPHKGAPNPAVVT-PPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325
Score = 58.5 bits (140), Expect = 5e-08
Identities = 102/415 (24%), Positives = 156/415 (37%), Gaps = 43/415 (10%)
Query: 1 MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLL 60
+ +T +P +E T S G PP + A+P+ P P+ +
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA-V 1407
Query: 61 VPVGP-RPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGK 119
+P+ P + P P+ +A P + P+ PA A GG AT +
Sbjct: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPP----AVTPVSLKKAPATSAPKGGPATPSSKG 1463
Query: 120 EEA--GKEEPPPLTPPA--RCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEV 175
+ P P PPA + A +KAPA P A T+ ++ KEV
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP----MGAPTLPAVIPSSP---KEV 1516
Query: 176 LASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPA-ECRE 234
A+P SR ++ +T T AP++ + + + P K+PA +
Sbjct: 1517 PATP----SSRRDPIAPTATLLSKKT-PATLAPKE---ALIPPAMTVPSPKKTPAIPTPK 1568
Query: 235 EHSKTPEERSLPSDLAFNGDLAKAASSE----LPADISKP---WIPSSPA--PSSENGGP 285
E TP + S A K A S +P ++ P P+ PA P S GP
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Query: 286 ASPGLPAEASGSGPGSPHLHPPDKSSPCH-SQLLEAQTPEASQASPCPAVTPSAPSAALP 344
A+P P S P +P +SP + + A P+AS+ P P+A L
Sbjct: 1629 ATPA-PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK-GPTALKEVLV 1686
Query: 345 DEGSRHTPSPGLPAEGAPEAPRPS--SPP--PEVLEPHSLDQPPAT-SPRPLIEV 394
TP P P+ + S SPP P+ + P +T +P PL+ V
Sbjct: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741
Score = 37.4 bits (85), Expect = 0.13
Identities = 103/433 (23%), Positives = 146/433 (33%), Gaps = 56/433 (12%)
Query: 264 PADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQ--LLEAQ 321
P S +P AP + P G P + SP + P K +P S L A
Sbjct: 83 PQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVAL 142
Query: 322 TPEASQASPC--PAVTPSAPSAALPDEGSRHTPS-PGLPAEGAPEAPRPSSPPPEVLEPH 378
P + Q S P + S PS A+ + GS T S P P+E P+ P V P
Sbjct: 143 APHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSE--PKTNLNKVPSEVVPNPK 200
Query: 379 SLDQPP---------ATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFS 429
PP +P I+ G + L +T P+ T+L
Sbjct: 201 GTPSPPCIVSTVPYHCVTPMASIQSG-VASLPQTTPT--------------TTL------ 239
Query: 430 EGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGV 489
+ SP Q ++ S+ PQ GS L+L P + SLS + P S
Sbjct: 240 --AIASP-QVKDTTISSVLISPQNPGS-LSLKGPVSPPAALSLSTQ---SLPVVTSSQKT 292
Query: 490 WRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPS 549
++PP PI+ S A + S V GQ SA S + D S
Sbjct: 293 AGPNTPPDFPISLGSHLAPLHQ-------SSFGSVQLLGQTGPSALSDPTVKTISVDHSS 345
Query: 550 MSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQES-PLPLATR 608
+ P P+ E +P T + ++ + + S L +AT
Sbjct: 346 TGASYPSQRSVIPPLPS-RNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATS 404
Query: 609 EAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDL 668
+ P +L A P V G V T+A A TT T
Sbjct: 405 FSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT---TFEVAT 461
Query: 669 CRASPEPPGPESS 681
C + P GP S+
Sbjct: 462 CVSPPMSSGPISN 474
Score = 33.1 bits (74), Expect = 2.4
Identities = 41/158 (25%), Positives = 61/158 (38%), Gaps = 28/158 (17%)
Query: 1402 GETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLA 1461
G + P ++G+ + P P +P A S +SP + PA P P G+ L +
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS--SSPKKAPATPAPMGAPTL--PAVI 1509
Query: 1462 ASSSKAV-----ARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEAS 1516
SS K V +RR+ A L + A A +E L P + PS + P
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPT--ATLLSKKTPATLAPKEALIPPAMTVPSPKKTP----- 1562
Query: 1517 QTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPS 1554
A + PA S + + PPA +PS
Sbjct: 1563 ------------AIPTPKEAPATPSSKEASSPPAVTPS 1588
Score = 32.3 bits (72), Expect = 4.1
Identities = 79/369 (21%), Positives = 118/369 (31%), Gaps = 59/369 (15%)
Query: 44 PRALPAKPALPAKPS-----LLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLP 98
P L + P++ S L P+ P P+ L ++PS N P P
Sbjct: 155 PNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP--------- 205
Query: 99 FAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAA 158
P + ++ ++G P TP A AS +
Sbjct: 206 ----PCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAI-------------ASPQVKD 248
Query: 159 TTVEEILAKMEQPRKEVLASPD------RLWGSRLTFNHDGSSRYGPRT-------YGTT 205
TT+ +L + P L P L L GP T G+
Sbjct: 249 TTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSH 308
Query: 206 TAPRDED--GSTLFRGWSQEGPVKSPA--ECREEHSKT----PEERSLPSDLAFNGDLAK 257
AP + GS G + + P +HS T P +RS+ L ++
Sbjct: 309 LAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVP 368
Query: 258 AASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSP--CHS 315
A + P + P + PS+ + SP + S SP KSSP +
Sbjct: 369 ATVAAFP--VVAPSV--DKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYH 424
Query: 316 QLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAP-RPSSPPPEV 374
L AQ P +S + VT AA P P P + P+SP V
Sbjct: 425 YPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALV 484
Query: 375 LEPHSLDQP 383
+ P + +P
Sbjct: 485 MAPVAPKEP 493
Score = 31.6 bits (70), Expect = 7.0
Identities = 30/114 (26%), Positives = 40/114 (35%), Gaps = 4/114 (3%)
Query: 1440 PGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEP 1499
P PA P P + L SSS AR A G+ +GA A
Sbjct: 896 PKEGPATPAPKQAPALS----MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951
Query: 1500 GRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSP 1553
G + PS + P A+ G + + + + PA T P GP SP
Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Score = 31.2 bits (69), Expect = 9.1
Identities = 33/136 (24%), Positives = 43/136 (31%), Gaps = 16/136 (11%)
Query: 1421 PHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGG 1480
PH P A+ SP PA PP G+ A + G G
Sbjct: 1282 PHKGAPN----PAVVTPPSPKGGPATSPPKGAP------------TPPAATPPSPKGSPG 1325
Query: 1481 LLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQT 1540
+GA A G + P+ P G + +G +A GPA T
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 1541 SRRPSQGPPARSPSQD 1556
P +GP SP D
Sbjct: 1386 PPSPKRGPAIPSPKGD 1401
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 80.9 bits (198), Expect = 1e-14
Identities = 145/678 (21%), Positives = 236/678 (34%), Gaps = 78/678 (11%)
Query: 26 PTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPP-RGPLAELPSARKMNML 84
P PG + PP +P P P + AKP P +PP + P PS ++
Sbjct: 469 PPSQLPGPAKP-PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
Query: 85 AGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKE-EPPPLTPPARCAAPGGVR 143
P GS +P P PA ++ ++T+ + +GK +PP ++P A+ G+
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Query: 144 KAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGS--------- 194
K P T E +L E+ S FN +
Sbjct: 586 KTICPL--------CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC 637
Query: 195 -SRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNG 253
+ R G AP + PV + + + S P++ S D A
Sbjct: 638 LNCQMKRALGGDLAPVPSSPQPKLK----TAPVTTTSAVSKS-SPQPQQTSPKKDAAPKQ 692
Query: 254 DLAKAASSELPADISK-PWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSP 312
DL+KA + P + K P + SP+ ++ P EA +P P S
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ--------PPEADSLSKPAPPKEPSVPSEQ 744
Query: 313 CHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPP 372
+ + + + + P + S+ + PD S S + P S+ P
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA-EEKTTPPLKTDSAKPS 803
Query: 373 EVLEPHSLDQPPATS---PRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFS 429
+ P P S PRP D G E+KG + P VQ++
Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPAS------DSKIISHPGPSSESKGQKQVDP---VQKK-- 852
Query: 430 EGVLQSPSQDQEKLGGSLAALPQGQGSQLALD-RPFGAESNWSLSQSFEWTFPTRPSGLG 488
+ P + Q K+ A P +GS RP ++ + QS + +R L
Sbjct: 853 ----EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908
Query: 489 VWRLDSPPPSPITEASEAAEAAEAGNLA--VSSREEGVSQQGQGAGSAPSGSGSSWVQGD 546
+ + P S T E G A S +S GQ + SG G+ Q
Sbjct: 909 LGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAP 968
Query: 547 DPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLA 606
PS T +G +S Q P P + +P + T ++ E + E ++P
Sbjct: 969 APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAE--------QAPTVKR 1020
Query: 607 TREAALPILEPVLGQEQPAAPDQPCVL---FADAPEPGQALPVEEEAVTLARAE------ 657
T P P+ + A Q VL +P+P P+ + + + +
Sbjct: 1021 TETEKKP--PPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
Query: 658 TTQARTEAQDLCRASPEP 675
T+ + + +LC +P P
Sbjct: 1079 CTECKNQVCNLCGFNPTP 1096
Score = 64.7 bits (156), Expect = 7e-10
Identities = 151/713 (21%), Positives = 245/713 (34%), Gaps = 101/713 (14%)
Query: 25 VPTGSEPGDTRAKPPVKPK------PRALPAKPALPAKPSLLVPVGP-RPPRGPLAELPS 77
+P PG + PK P + ++P KP GP + P+ A+LP
Sbjct: 219 IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ----GPTQTPQTDHAKLPL 274
Query: 78 ARKMNMLAGPQP---YGGSKRP-LPFAPRPAVEASTGGEA-TQETGKEEAGKEEPPPLTP 132
R + Q G S +P LP +P ++ T G+ Q+ G E K +P P P
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE---KSQPGPAKP 331
Query: 133 PARCAA-----------------PGGVRKAPA-PFRPASERFAATTVEEILAKMEQPRKE 174
PA+ + P G K PA P PA T E+ EQP +
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK--PSSEQPGPK 389
Query: 175 VLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECRE 234
LA P + + G ++ + GT + G L GP K+P + +
Sbjct: 390 ALAQPPGV--GKTPAQQPGPAKPPTQQVGTPKPLAQQPG--LQSPAKAPGPTKTPVQ-QP 444
Query: 235 EHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPA-PSSENGGPASPGLPAE 293
K P +++ P + S+LP P PA P + G A P P++
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP--PSQ 502
Query: 294 ASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPS 353
GS P P K SP Q + P S P+ +P+ + ++
Sbjct: 503 QPGSTKPPPQQPGPAKPSP--QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Query: 354 PGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATS-PRPLIEVGELLDLTRTFPSGGEEEA 412
G G P P SP S QPP+ P+ + + +L P
Sbjct: 561 TG---SGKPLQPPTVSP--------SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609
Query: 413 KGDAHLRPTSLVQRRFSEGVLQSPS------QDQEKLGGSLAALPQGQGSQLALDRPFGA 466
+ SL + + + Q + LGG LA +P +L +
Sbjct: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL---KTAPV 666
Query: 467 ESNWSLSQSFEWTFPTRPSGLGVWRLD--------SPPP---------SPITEASEAAEA 509
+ ++S+S T P + D PPP SP +A + EA
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
Query: 510 AEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPL 569
A S+Q + + V+ P+ L ++P P+ +
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK---PTTDLVSSSSATTKPDIPSSKV 783
Query: 570 EPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQ 629
+ + TP L A+ +S P + SP A+P P + + P
Sbjct: 784 QSQAEEKTTPPLKTDSAKPS-QSFPPTGEKVSPFD----SKAIP--RPASDSKIISHPGP 836
Query: 630 PCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSS 682
+++ Q PV+++ + +A+ + + SP PPGP ++
Sbjct: 837 S----SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA 885
Score = 60.5 bits (145), Expect = 1e-08
Identities = 102/441 (23%), Positives = 155/441 (35%), Gaps = 67/441 (15%)
Query: 8 ESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRP 67
ES + P P + + G P +P P PA+P+ KP P +P
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
Query: 68 P-RGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEE 126
P + P P A+ + P GS++P P P A G +T ++ G +
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQPGPAK 409
Query: 127 PPPL---TPPARCAAPG--GVRKAPAPFRPASERFAATTVEEILA---KMEQPRKEVLAS 178
PP TP PG KAP P + ++ + A K +
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 179 PDRLWG-SRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHS 237
P +L G ++ G ++ P+ G+ P + GST Q GP K P+ + +
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK-PPPQQPGPAK-PSPQQPGST 527
Query: 238 KTPEER---SLPSDLAFNGDLAKAASSELPADIS-----KPWIPSSPAPSSENGGPASPG 289
K P ++ + PS A AK ++ + +S KP P + +PS++ P S G
Sbjct: 528 KPPSQQPGSAKPS--AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ--PPSQG 583
Query: 290 LP--------------------------------AEASGSGPGSPHLHPPDKSSPCHSQL 317
LP G P +PHL + + Q+
Sbjct: 584 LPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP-NPHLTEVKEWLCLNCQM 642
Query: 318 LEA----QTPEASQASP----CPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSS 369
A P S P P T SA S + P P + +AP P
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702
Query: 370 PPPEVLEPHSLDQPPATSPRP 390
PPP V +P P A + +P
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQP 723
Score = 37.7 bits (86), Expect = 0.098
Identities = 22/65 (33%), Positives = 28/65 (43%)
Query: 328 ASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATS 387
AS P+ +PS S + S + A+ P P P PPP P PP TS
Sbjct: 2373 ASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS 2432
Query: 388 PRPLI 392
P+P I
Sbjct: 2433 PKPTI 2437
Score = 35.8 bits (81), Expect = 0.37
Identities = 68/323 (21%), Positives = 113/323 (34%), Gaps = 51/323 (15%)
Query: 1403 ETSGPETQGEDY----SSSSLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEE 1458
+ S P+T+ D S P P+ P ++ +PG+ PA+ P
Sbjct: 277 DASRPQTKQADIVRGESVKPSLPSPSKPPIQQ-------PTPGKPPAQQPGH-------- 321
Query: 1459 MLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQT 1518
S A+ + SGL L ++ G + V PG PP+ QP G A
Sbjct: 322 ---EKSQPGPAKPPAQPSGLTKPLAQQ---PGTVKPPVQPPGTTKPPA---QPLGPAKPP 372
Query: 1519 EDVDGTWGSSAARWSDQGPAQ---TSRRPSQGP-PARSPSQDFSFIEDTEILDSAMYRSR 1574
G+ S+ + + AQ + P+Q P PA+ P+Q + ++
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 1575 ANLGRKRGHRAPVIRPG-GTLGLSEAADSDAHLFQDSTEPRASRVPSSDEEVVEEPQSRR 1633
A K PV +PG G + +A Q S++P + ++P +
Sbjct: 433 APGPTK----TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 1634 TRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQKESAVQRSKSCKVP 1693
P SA +P + + +K S ++ + S + P
Sbjct: 489 PP-------------PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS-QQP 534
Query: 1694 GLGKPLTLPPKPEKSSGSEGSSP 1716
G KP P P K S + + P
Sbjct: 535 GSAKPSAQQPSPAKPSAQQSTKP 557
Score = 32.7 bits (73), Expect = 3.1
Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 1/58 (1%)
Query: 352 PSPGLPAEGAPEAPRPSSPPPEVLEPHSLD-QPPATSPRPLIEVGELLDLTRTFPSGG 408
P P P P P P+SP P +L L P T+ PL + L+ T S G
Sbjct: 2415 PPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG 2472
Score = 32.3 bits (72), Expect = 4.1
Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 34 TRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYG 91
T A PPV PKP ++P+ +P P P P+ + +LP+ + P+P G
Sbjct: 2480 TTAPPPVPPKPSSIPSGLVFTHRPEPSKP--PIAPKPVIPQLPTTTQKPTDIHPKPTG 2535
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 80.9 bits (198), Expect = 1e-14
Identities = 145/678 (21%), Positives = 236/678 (34%), Gaps = 78/678 (11%)
Query: 26 PTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPP-RGPLAELPSARKMNML 84
P PG + PP +P P P + AKP P +PP + P PS ++
Sbjct: 469 PPSQLPGPAKP-PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
Query: 85 AGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKE-EPPPLTPPARCAAPGGVR 143
P GS +P P PA ++ ++T+ + +GK +PP ++P A+ G+
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Query: 144 KAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGS--------- 194
K P T E +L E+ S FN +
Sbjct: 586 KTICPL--------CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC 637
Query: 195 -SRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNG 253
+ R G AP + PV + + + S P++ S D A
Sbjct: 638 LNCQMKRALGGDLAPVPSSPQPKLK----TAPVTTTSAVSKS-SPQPQQTSPKKDAAPKQ 692
Query: 254 DLAKAASSELPADISK-PWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSP 312
DL+KA + P + K P + SP+ ++ P EA +P P S
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ--------PPEADSLSKPAPPKEPSVPSEQ 744
Query: 313 CHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPP 372
+ + + + + P + S+ + PD S S + P S+ P
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA-EEKTTPPLKTDSAKPS 803
Query: 373 EVLEPHSLDQPPATS---PRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFS 429
+ P P S PRP D G E+KG + P VQ++
Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPAS------DSKIISHPGPSSESKGQKQVDP---VQKK-- 852
Query: 430 EGVLQSPSQDQEKLGGSLAALPQGQGSQLALD-RPFGAESNWSLSQSFEWTFPTRPSGLG 488
+ P + Q K+ A P +GS RP ++ + QS + +R L
Sbjct: 853 ----EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908
Query: 489 VWRLDSPPPSPITEASEAAEAAEAGNLA--VSSREEGVSQQGQGAGSAPSGSGSSWVQGD 546
+ + P S T E G A S +S GQ + SG G+ Q
Sbjct: 909 LGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAP 968
Query: 547 DPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLA 606
PS T +G +S Q P P + +P + T ++ E + E ++P
Sbjct: 969 APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAE--------QAPTVKR 1020
Query: 607 TREAALPILEPVLGQEQPAAPDQPCVL---FADAPEPGQALPVEEEAVTLARAE------ 657
T P P+ + A Q VL +P+P P+ + + + +
Sbjct: 1021 TETEKKP--PPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
Query: 658 TTQARTEAQDLCRASPEP 675
T+ + + +LC +P P
Sbjct: 1079 CTECKNQVCNLCGFNPTP 1096
Score = 64.7 bits (156), Expect = 7e-10
Identities = 151/713 (21%), Positives = 245/713 (34%), Gaps = 101/713 (14%)
Query: 25 VPTGSEPGDTRAKPPVKPK------PRALPAKPALPAKPSLLVPVGP-RPPRGPLAELPS 77
+P PG + PK P + ++P KP GP + P+ A+LP
Sbjct: 219 IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ----GPTQTPQTDHAKLPL 274
Query: 78 ARKMNMLAGPQP---YGGSKRP-LPFAPRPAVEASTGGEA-TQETGKEEAGKEEPPPLTP 132
R + Q G S +P LP +P ++ T G+ Q+ G E K +P P P
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE---KSQPGPAKP 331
Query: 133 PARCAA-----------------PGGVRKAPA-PFRPASERFAATTVEEILAKMEQPRKE 174
PA+ + P G K PA P PA T E+ EQP +
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK--PSSEQPGPK 389
Query: 175 VLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECRE 234
LA P + + G ++ + GT + G L GP K+P + +
Sbjct: 390 ALAQPPGV--GKTPAQQPGPAKPPTQQVGTPKPLAQQPG--LQSPAKAPGPTKTPVQ-QP 444
Query: 235 EHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPA-PSSENGGPASPGLPAE 293
K P +++ P + S+LP P PA P + G A P P++
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP--PSQ 502
Query: 294 ASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPS 353
GS P P K SP Q + P S P+ +P+ + ++
Sbjct: 503 QPGSTKPPPQQPGPAKPSP--QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Query: 354 PGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATS-PRPLIEVGELLDLTRTFPSGGEEEA 412
G G P P SP S QPP+ P+ + + +L P
Sbjct: 561 TG---SGKPLQPPTVSP--------SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609
Query: 413 KGDAHLRPTSLVQRRFSEGVLQSPS------QDQEKLGGSLAALPQGQGSQLALDRPFGA 466
+ SL + + + Q + LGG LA +P +L +
Sbjct: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL---KTAPV 666
Query: 467 ESNWSLSQSFEWTFPTRPSGLGVWRLD--------SPPP---------SPITEASEAAEA 509
+ ++S+S T P + D PPP SP +A + EA
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
Query: 510 AEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPL 569
A S+Q + + V+ P+ L ++P P+ +
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK---PTTDLVSSSSATTKPDIPSSKV 783
Query: 570 EPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQ 629
+ + TP L A+ +S P + SP A+P P + + P
Sbjct: 784 QSQAEEKTTPPLKTDSAKPS-QSFPPTGEKVSPFD----SKAIP--RPASDSKIISHPGP 836
Query: 630 PCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSS 682
+++ Q PV+++ + +A+ + + SP PPGP ++
Sbjct: 837 S----SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA 885
Score = 60.5 bits (145), Expect = 1e-08
Identities = 102/441 (23%), Positives = 155/441 (35%), Gaps = 67/441 (15%)
Query: 8 ESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRP 67
ES + P P + + G P +P P PA+P+ KP P +P
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
Query: 68 P-RGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEE 126
P + P P A+ + P GS++P P P A G +T ++ G +
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQPGPAK 409
Query: 127 PPPL---TPPARCAAPG--GVRKAPAPFRPASERFAATTVEEILA---KMEQPRKEVLAS 178
PP TP PG KAP P + ++ + A K +
Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 179 PDRLWG-SRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHS 237
P +L G ++ G ++ P+ G+ P + GST Q GP K P+ + +
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK-PPPQQPGPAK-PSPQQPGST 527
Query: 238 KTPEER---SLPSDLAFNGDLAKAASSELPADIS-----KPWIPSSPAPSSENGGPASPG 289
K P ++ + PS A AK ++ + +S KP P + +PS++ P S G
Sbjct: 528 KPPSQQPGSAKPS--AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ--PPSQG 583
Query: 290 LP--------------------------------AEASGSGPGSPHLHPPDKSSPCHSQL 317
LP G P +PHL + + Q+
Sbjct: 584 LPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP-NPHLTEVKEWLCLNCQM 642
Query: 318 LEA----QTPEASQASP----CPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSS 369
A P S P P T SA S + P P + +AP P
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702
Query: 370 PPPEVLEPHSLDQPPATSPRP 390
PPP V +P P A + +P
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQP 723
Score = 37.7 bits (86), Expect = 0.098
Identities = 22/65 (33%), Positives = 28/65 (43%)
Query: 328 ASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATS 387
AS P+ +PS S + S + A+ P P P PPP P PP TS
Sbjct: 2373 ASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS 2432
Query: 388 PRPLI 392
P+P I
Sbjct: 2433 PKPTI 2437
Score = 35.8 bits (81), Expect = 0.37
Identities = 68/323 (21%), Positives = 113/323 (34%), Gaps = 51/323 (15%)
Query: 1403 ETSGPETQGEDY----SSSSLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEE 1458
+ S P+T+ D S P P+ P ++ +PG+ PA+ P
Sbjct: 277 DASRPQTKQADIVRGESVKPSLPSPSKPPIQQ-------PTPGKPPAQQPGH-------- 321
Query: 1459 MLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQT 1518
S A+ + SGL L ++ G + V PG PP+ QP G A
Sbjct: 322 ---EKSQPGPAKPPAQPSGLTKPLAQQ---PGTVKPPVQPPGTTKPPA---QPLGPAKPP 372
Query: 1519 EDVDGTWGSSAARWSDQGPAQ---TSRRPSQGP-PARSPSQDFSFIEDTEILDSAMYRSR 1574
G+ S+ + + AQ + P+Q P PA+ P+Q + ++
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 1575 ANLGRKRGHRAPVIRPG-GTLGLSEAADSDAHLFQDSTEPRASRVPSSDEEVVEEPQSRR 1633
A K PV +PG G + +A Q S++P + ++P +
Sbjct: 433 APGPTK----TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 1634 TRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQKESAVQRSKSCKVP 1693
P SA +P + + +K S ++ + S + P
Sbjct: 489 PP-------------PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS-QQP 534
Query: 1694 GLGKPLTLPPKPEKSSGSEGSSP 1716
G KP P P K S + + P
Sbjct: 535 GSAKPSAQQPSPAKPSAQQSTKP 557
Score = 32.7 bits (73), Expect = 3.1
Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 1/58 (1%)
Query: 352 PSPGLPAEGAPEAPRPSSPPPEVLEPHSLD-QPPATSPRPLIEVGELLDLTRTFPSGG 408
P P P P P P+SP P +L L P T+ PL + L+ T S G
Sbjct: 2415 PPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG 2472
Score = 32.3 bits (72), Expect = 4.1
Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 34 TRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYG 91
T A PPV PKP ++P+ +P P P P+ + +LP+ + P+P G
Sbjct: 2480 TTAPPPVPPKPSSIPSGLVFTHRPEPSKP--PIAPKPVIPQLPTTTQKPTDIHPKPTG 2535
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 74.7 bits (182), Expect = 7e-13
Identities = 170/695 (24%), Positives = 240/695 (34%), Gaps = 123/695 (17%)
Query: 41 KPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGP---QP-------Y 90
K K A PA A P LL P P PR P P+A ++ AG +P
Sbjct: 7 KAKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 91 GGSKRPLPFAPRPAVEASTGGEATQETGKEEA---GKEEPPPL-TPPARCAAPGGVRKAP 146
GG+ P APR S G + + A G+ PP T P ++PG
Sbjct: 66 GGATIP-ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124
Query: 147 APFRPASERFAATTVEEILAK---MEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYG 203
P P ++ + EE +A+ E P++ L++ R S T +
Sbjct: 125 RP-GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
Query: 204 TTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKT---PEERSLPSDLAFNGDLAKAAS 260
T + EGP KS + EHS T P R PS G L + AS
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSA-SEHSTTEPSPAARRRPS---AGGGLQRPAS 239
Query: 261 SELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGS---PHLHPPDKSS-----P 312
L + + P+ PS+ G P +P P++ G + P + PP K + P
Sbjct: 240 RSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 313 CHSQLLEAQTPEASQ----------ASPCPAVTPSAPSAALPDEGSRHTPS--PGLPAEG 360
S L +P ++ A+P PA P +P A P + +PS P L
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358
Query: 361 APEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRP 420
+P A PS PP + P + PP+ P I+V L T PS
Sbjct: 359 SPPATPPSQAPPSMTTP-PMQAPPSLQTIPPIQVPHSL----TSPS-------------- 399
Query: 421 TSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTF 480
LQ+P SL A L F S S T
Sbjct: 400 ------------LQAPPSPLAL--SSLQATTSLGSPTLQATHSFLTMSPRQTQASL--TS 443
Query: 481 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS 540
P+RP+ +PP SP +A + A+ ++S P+ S
Sbjct: 444 PSRPA-------STPPDSPPLQAPLSLPASPPLQTSLS----------------PAVSPL 480
Query: 541 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE 600
S P +L+ Q ++ + PL T+ + P Q + PL
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPL-ETQSSLAPPSLQTPPASLTTPPLENLP 539
Query: 601 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ 660
S P + A+ P+ P L E P P PC L AP P E ++A
Sbjct: 540 SLAPPPLQTASAPLTTPHL--ETPPCP-APCPL--QAPPSPLTTPPPETPSSIATPPPQA 594
Query: 661 ARTEAQDLCRASPEPP-GPESSSRWLDDLLASPPP 694
A + P PP P LA+PPP
Sbjct: 595 PPALASPPLQGLPSPPLSP----------LATPPP 619
Score = 66.2 bits (160), Expect = 3e-10
Identities = 192/835 (22%), Positives = 274/835 (32%), Gaps = 179/835 (21%)
Query: 5 TLRESSAMASPLPREMEEELVPTGSEP--------GDTRAKPPVKPKPRALPAKPALPAK 56
T R + + P P+ ++ P + P G + P P P A+P P
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 57 PSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQE 116
+ PP PLA PLP AP P+ A +
Sbjct: 322 NAATPLPATLPPSPPLA---------------------TPLPLAP-PSPSAPPSLQTLPS 359
Query: 117 TGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILA--KMEQPRKE 174
PP TPP++ AP + P P+ + V L ++ P
Sbjct: 360 -----------PPATPPSQ--APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Query: 175 V----LASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPA 230
+ L + L L H + +T + T+P ST + P+ PA
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP-SRPASTPPDSPPLQAPLSLPA 465
Query: 231 ECREEHSKTPEERSLPSDLAFN--GDLAKAASSELPADISKPWIP-----SSPAPSSENG 283
+ S +P L S L + L+ AS A +S +P SS AP S
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525
Query: 284 GPAS---------PGL---PAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPC 331
PAS P L P + + + +PHL P +PC Q P + +P
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC-----PLQAPPSPLTTP- 579
Query: 332 PAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRP--SSPPPEVLEPHSLDQPPATSPR 389
P TPS+ A P + SP P +G P P ++PPP+ P L PP +P
Sbjct: 580 PPETPSS-IATPPPQAPPALASP--PLQGLPSPPLSPLATPPPQA--PPXLALPPLQAPP 634
Query: 390 PLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFS---EGVLQSPSQDQEKLGGS 446
L L P A L+Q FS +Q+P S
Sbjct: 635 SPPASPPLSPLATPSPQAPNALA--------VHLLQAPFSPPPSPPVQAPFSPPASPPVS 686
Query: 447 LAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSP-ITEASE 505
+A P Q P P+ P+ SPP SP T +
Sbjct: 687 PSATPPSQAPPSLAAPPLQVP-------------PSPPA--------SPPMSPSATPPPQ 725
Query: 506 AAEAAEAGNLAVSSREEGVSQQGQGAGSAPS-----GSGSSWVQGDDPS---MSLTQKGD 557
A A L V A P + V P+ MS K
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 558 GESQPQFPAVPLEPLPTTEGT-PGLPLQQAEERYESQEPLAGQESPLPLATREAALPILE 616
++ P PL+ LP+ + PG QA + P++ +P P A A P+L
Sbjct: 786 PQAPPALATPPLQALPSPPASFPG----QAPFSPSASLPMSPLATPPPQAPPVLAAPLL- 840
Query: 617 PVLGQEQPAAPDQPCVLF-ADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEP 675
Q P+ P P + P PG V +TLA A
Sbjct: 841 ----QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA------------------- 877
Query: 676 PGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCS-EGLLGWSQKDLQSEFGI 734
PGP PPPS + +G +L S +T + E L G+ D E G
Sbjct: 878 PGP------------PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY---DSGPEGGA 922
Query: 735 TGDPQP----SSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQGAGEG 785
P P ++ P++W +G + RG PG W G G+ +G
Sbjct: 923 AASPPPDAELAACHPAAWSRGPAPPLAF-----RGAPG-APLPWPPATGPGSADG 971
Score = 63.5 bits (153), Expect = 2e-09
Identities = 181/737 (24%), Positives = 233/737 (31%), Gaps = 90/737 (12%)
Query: 4 STLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALP--------AKPALPA 55
+TL S +A+PLP P + T PP P +A P A P+L
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQ---TLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
Query: 56 KPSLLVP---VGP--RPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTG 110
P + VP P + P PLA L S + L P + L +PR + T
Sbjct: 386 IPPIQVPHSLTSPSLQAPPSPLA-LSSLQATTSLGSPT-LQATHSFLTMSPRQTQASLTS 443
Query: 111 GEATQETGKEEAGKEEPP--PLTPPARCAAPGGVRKAPAPFR----PASERFAATTVEEI 164
T + + P P +PP + + V +P A A+ + +
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503
Query: 165 LAKMEQPRKEVLAS--PDRLW---GSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRG 219
L+ + P E +S P L S T + P T +AP T
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL-----TTPHL 558
Query: 220 WSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPS 279
+ P P + TP + PS +A A A + P P P SP +
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPET-PSSIATPPPQAPPALASPPLQ-GLPSPPLSPLAT 616
Query: 280 SENGGPASPGLPA-EASGSGPGSPHLHPPDKSSPCHSQLLEA---QTPEASQASPCPAVT 335
P LP +A S P SP L P SP L Q P + SP P
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQA 675
Query: 336 PSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSP---RPLI 392
P +P A+ P S PS P+ AP P SPP S PP P P +
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
Query: 393 EVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQ 452
+V P P V + LQ P L S A P
Sbjct: 736 QV----------PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 453 GQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEA 512
Q P A S SF P PS S P SP+ A A
Sbjct: 786 PQAPPALATPPLQALP--SPPASFPGQAPFSPSA-------SLPMSPLATPPPQAPPVLA 836
Query: 513 GNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPL 572
L S Q P+ + V G +++L G + P+ L
Sbjct: 837 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA-PGPPPPPSRSPSSTLSG- 894
Query: 573 PTTEGTPGLPLQQAEE--RYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQP 630
P G EE Y+S SP P +A L P PA P
Sbjct: 895 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP----DAELAACHPAAWSRGPAPP--- 947
Query: 631 CVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLA 690
A PG LP A LC E GPES++ L
Sbjct: 948 ---LAFRGAPGAPLP----------WPPATGPGSADGLCTIY-ETEGPESATPAPGALDP 993
Query: 691 SPPP--SGGGARRGAGA 705
P P SGG A GAGA
Sbjct: 994 GPSPGTSGGKAAAGAGA 1010
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 73.9 bits (180), Expect = 1e-12
Identities = 180/736 (24%), Positives = 243/736 (33%), Gaps = 111/736 (15%)
Query: 41 KPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGP---QPYGGSKRPL 97
K K A PA A P LL P P PR P P+A ++ AG +P +
Sbjct: 7 KAKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 98 PFAPRPAVEASTGGEATQETGKEEAGKEEPPPL-TPPARCAAPGGVRKAPAPFRPASERF 156
A P G T G+ PP T P ++PG P P ++
Sbjct: 66 GGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP-GPLGQKG 124
Query: 157 AATTVEEILAK---MEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDG 213
+ EE +A+ E P++ L++ R S T + T
Sbjct: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184
Query: 214 STLFRGWSQEGPVKSPAECREEHSKT---PEERSLPSDLAFNGDLAKAASSELPADISKP 270
+ EGP KS + EHS T P R PS G L + AS L + +
Sbjct: 185 PSARPRPPTEGPRKSVSSA-SEHSTTEPSPAARRRPSA---GGGLQRPASRSLSSSATPL 240
Query: 271 WIPSSPAPSSENGGPASPGLPAEASGSGPGS---PHLHPPDKSS-----PCHSQLLEAQT 322
P+ PS+ G P +P P++ G + P + PP K + P S L +
Sbjct: 241 SSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 299
Query: 323 PEASQASPCPAVTPS-----APSAALPDEGSRHTPSPGLPAEGA----PEAPRPSSPPPE 373
P A P P+ PS +P A P + + SP L A + P ++PPP+
Sbjct: 300 PSAP---PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356
Query: 374 VLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFS---E 430
P +L PP +P L L P A L+Q FS
Sbjct: 357 A--PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA--------VHLLQAPFSPPPS 406
Query: 431 GVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVW 490
+Q+P S +A P Q P + S + P
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ----- 461
Query: 491 RLDSPPP---SPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDD 547
+PPP P+ A +A A LA + S G AP
Sbjct: 462 ---APPPLAAPPLQLAKPPPQAPPA--LATPPLQALPSPPASFPGQAPFS---------- 506
Query: 548 PSMSLTQKGDGESQPQFPAVPLEPL-PTTEGTPGLPLQQAEERYESQEP----------L 596
PS SL PQ P V PL P P QA R + P L
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 566
Query: 597 AGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVL--FADAPEPGQALPVEEEAVTLA 654
A P P +R + + P L +A P L + PE G A +A A
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626
Query: 655 RAETTQARTEAQDLC-RASPEPP----------------------GPESSSRWLDDLLAS 691
+R A L R +P P GPES++ L
Sbjct: 627 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 686
Query: 692 PPP--SGGGARRGAGA 705
P P SGG A GAGA
Sbjct: 687 PSPGTSGGKAAAGAGA 702
Score = 60.8 bits (146), Expect = 1e-08
Identities = 101/413 (24%), Positives = 141/413 (34%), Gaps = 44/413 (10%)
Query: 4 STLRESSAMASPLPREMEEELVPTGSEPGDTRAK--PPVK---PKPRALPAKPALPAKPS 58
+T+ ES+ A P T P R + PP K P P + P + + +P
Sbjct: 68 ATIPESAPRAGP---------TRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 118
Query: 59 LLVPVGPR------PPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGE 112
L G R RG E P ++ A G P P P PA+ +
Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG----PTPGTPSPAMARRSRAA 174
Query: 113 ATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASER--FAATTVEEILAKMEQ 170
T+ A P P T R + + PA+ R A ++ ++
Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234
Query: 171 PRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGT-------TTAPRDEDGSTLFRGWSQE 223
L+SP R S + P+ G T PR + L G
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL--GPLSS 292
Query: 224 GPVKSPA-ECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSP-APSSE 281
P+ +P+ S P ++LPS A A + + ++PS P +P +
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352
Query: 282 NGGPASPGL---PAEASGSGPGSPHLHPPDKSSPCHSQLLEA---QTPEASQASPCPAVT 335
A P L P +A S P SP L P SP L Q P + SP P
Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQA 411
Query: 336 PSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSP 388
P +P A+ P S PS P+ AP P SPP S PP P
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464
Score = 58.5 bits (140), Expect = 5e-08
Identities = 138/577 (23%), Positives = 196/577 (33%), Gaps = 103/577 (17%)
Query: 28 GSEPGDTRAKPPVKPKPRAL-PAKPALPAKPSLLVPVGP----RPPRGPLAELPSARKMN 82
G+E G R P +P+P P K A P RP G + P++R ++
Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234
Query: 83 M----LAGPQPYGGSKRPLPFAP-RPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCA 137
L+ P G S R P AP P+ G +A + PP +TPP + A
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR-----------PPQVTPPRKDA 283
Query: 138 APG------GVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNH 191
AP P+P P S A +++ + + P + S L L H
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPS-APPSLQTLPSPPATPPSQATTS---LGSPTLQATH 339
Query: 192 DGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAF 251
S P T P + + P PA TP ++ P+ LA
Sbjct: 340 --SFLPSPPLSPLATPPPQAPPALALP--PLQAPPSPPASPPLSPLATPSPQA-PNALAV 394
Query: 252 NGDLAKAASSELPAD-ISKPWIPSSPAPSSENGGPASPGLPAEAS----------GSGPG 300
+ L +A S P+ + P+ P + P S + P S P+ A+ S P
Sbjct: 395 H--LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452
Query: 301 SPHLHPPDKSSPCHS----QLLEA--QTPEASQASPC----------PAVTPSAPSAALP 344
SP PP ++ P + QL + Q P A P P P +PSA+LP
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512
Query: 345 DEGSRHTPSPGLPAEGAPEAPRPSSPP--PEVLEPHSLDQPPATSPRPLIEVGELLDLTR 402
P P AP P SPP P + P +PP P + L
Sbjct: 513 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR---RPPTPGPDTSVSGPRLTLALA 569
Query: 403 TFPS-----------GGEEEAKGDAHLRPTSLVQRRFSE----GVLQSPSQDQEKLGGSL 447
P G + A + T R + G SP D E
Sbjct: 570 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 629
Query: 448 AALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGL-GVWRLDSPP---------- 496
AA +G LA GA W + T P GL ++ + P
Sbjct: 630 AAWSRGPAPPLAFRGAPGAPLPWPPA-----TGPGSADGLCTIYETEGPESATPAPGALD 684
Query: 497 --PSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGA 531
PSP T +AA A AG + S ++ + + GA
Sbjct: 685 PGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 721
Score = 38.9 bits (89), Expect = 0.044
Identities = 83/333 (24%), Positives = 110/333 (33%), Gaps = 68/333 (20%)
Query: 10 SAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPR 69
S A+P + P P A PP+ P P P A P L + PP+
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL--QLAKPPPQ 479
Query: 70 GPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPP 129
P P+ + A P P PF+P ++ S PPP
Sbjct: 480 AP----PALATPPLQALPSPPASFPGQAPFSPSASLPMSP--------------LATPPP 521
Query: 130 LTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD-RLWGSRLT 188
PP AAP + + P P PAS ++ PR+ PD + G RLT
Sbjct: 522 QAPPV-LAAP--LLQVP-PSPPAS------------PTLQAPRRPPTPGPDTSVSGPRLT 565
Query: 189 FNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEE-RSLPS 247
G P STL GP A + TPEE R S
Sbjct: 566 L---------ALAPGPPPPPSRSPSSTL------SGP--DLAGHSSSATSTPEELRGYDS 608
Query: 248 DLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPP 307
+ +EL A W P + G P +P LP + +GPGS
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP-LPWPPA-TGPGS------ 660
Query: 308 DKSSPCHSQLLEAQTPEASQASPCPAVTPSAPS 340
C + E + PE+ A+P P PS
Sbjct: 661 -ADGLC--TIYETEGPES--ATPAPGALDPGPS 688
Score = 37.7 bits (86), Expect = 0.098
Identities = 53/187 (28%), Positives = 75/187 (40%), Gaps = 27/187 (14%)
Query: 1387 GLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFG----ASPGR 1442
G R PL R G+G + PE+ + + P + G A + +SPGR
Sbjct: 51 GAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGR 110
Query: 1443 C--PARPPPSGSQGL---LEEMLA---------ASSSKAVARRESAASGLGGLLEEEGAG 1488
RP P G +GL EE +A S+ A ARR+++ G
Sbjct: 111 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 170
Query: 1489 AGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTS-RRPSQG 1547
+ AA EV P PS RP+P E + SSA+ S P+ + RRPS G
Sbjct: 171 SRAAGTEVGLP--RPAPSARPRPPTEGPRKS------VSSASEHSTTEPSPAARRRPSAG 222
Query: 1548 PPARSPS 1554
+ P+
Sbjct: 223 GGLQRPA 229
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 73.6 bits (179), Expect = 2e-12
Identities = 182/748 (24%), Positives = 248/748 (33%), Gaps = 96/748 (12%)
Query: 41 KPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGP---QPY------- 90
K K A PA A P LL P P PR P P+A ++ AG +P
Sbjct: 7 KAKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 91 GGSKRPLPFAPRPAVEASTGGEATQETGKEEA---GKEEPPPL-TPPARCAAPGGVRKAP 146
GG+ P APR S G + + A G+ PP T P ++PG
Sbjct: 66 GGATIP-ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124
Query: 147 APFRPASERFAATTVEEILAK---MEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYG 203
P P ++ + EE +A+ E P++ L++ R S T +
Sbjct: 125 RP-GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
Query: 204 TTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKT---PEERSLPSDLAFNGDLAKAAS 260
T + EGP KS + EHS T P R PS G L + AS
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSA-SEHSTTEPSPAARRRPSA---GGGLQRPAS 239
Query: 261 SELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGS---PHLHPPDKSS-----P 312
L + + P+ PS+ G P +P P++ G + P + PP K + P
Sbjct: 240 RSLSSSATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 313 CHSQLLEAQTPEASQASPCPAVTPSAPSAA-----LPDEGSRHTPSPGLPAEGAPEAPRP 367
S L +P A+ S P P+ P ++ L PSP P P
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
Query: 368 SSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRR 427
++PP + SL P + + L L P A P+
Sbjct: 359 ATPPSQATT--SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
Query: 428 FSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTR-PSG 486
S SP Q L L P + PF ++ +S S T P++ P
Sbjct: 417 LSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA--TPPSQAPPS 473
Query: 487 LGVWRLDSPPPSPITEASEAAE----------AAEAGNLAVSSREEGVSQQGQGAGSAPS 536
L L PP P + + AA LA + + + PS
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS 533
Query: 537 GSGSSWVQGD-DPSMSLTQKGDGESQPQFPAVPLEPL-PTTEGTPGLPLQQAEERYESQE 594
S Q PS SL PQ P V PL P P QA R +
Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593
Query: 595 P----------LAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVL--FADAPEPGQ 642
P LA P P +R + + P L +A P L + PE G
Sbjct: 594 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 653
Query: 643 ALPVEEEAVTLARAETTQARTEAQDLC-RASPEPP----------------------GPE 679
A +A A +R A L R +P P GPE
Sbjct: 654 AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE 713
Query: 680 SSSRWLDDLLASPPP--SGGGARRGAGA 705
S++ L P P SGG A GAGA
Sbjct: 714 SATPAPGALDPGPSPGTSGGKAAAGAGA 741
Score = 60.8 bits (146), Expect = 1e-08
Identities = 95/369 (25%), Positives = 132/369 (35%), Gaps = 41/369 (11%)
Query: 33 DTRAKPPVKPKPRALPAKPALPAKPSLLVPVG---PRPP-RGPLAELPSARKMNMLAGPQ 88
DT P P P A + L P PRPP GP + SA + +
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS------ 216
Query: 89 PYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPG-GVRKAPA 147
+ P P A R S GG + + + P L+ PAR G +APA
Sbjct: 217 ----TTEPSPAARR---RPSAGGGLQRPASRSLSSSATP--LSSPARSGPSARGTPRAPA 267
Query: 148 -PFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTT 206
P +P + A ++ PRK+ + L S L ++ ++ T
Sbjct: 268 HPSQPKPKGLQALRPPQVTP----PRKDAAPALGPLSSSPLATPSPSAAL---QSQAPPT 320
Query: 207 APRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPAD 266
P S+L + P+ P+ S P ++LPS A A +
Sbjct: 321 LPATPHSSSLTCQLATPLPLAPPSP-----SAPPSLQTLPSPPATPPSQATTSLGSPTLQ 375
Query: 267 ISKPWIPSSP-APSSENGGPASPGL---PAEASGSGPGSPHLHPPDKSSPCHSQLLEA-- 320
+ ++PS P +P + A P L P +A S P SP L P SP L
Sbjct: 376 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 435
Query: 321 -QTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHS 379
Q P + SP P P +P A+ P S PS P+ AP P SPP S
Sbjct: 436 LQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 494
Query: 380 LDQPPATSP 388
PP P
Sbjct: 495 ATPPPQAPP 503
Score = 53.5 bits (127), Expect = 2e-06
Identities = 94/388 (24%), Positives = 129/388 (33%), Gaps = 70/388 (18%)
Query: 10 SAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPR 69
S +A+P P+ +P P A PP+ P P P A L P P PP
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-PPS 445
Query: 70 GPLA---ELPSARKMNMLAGP---QPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAG 123
P+ P++ ++ A P P + PL P P AT
Sbjct: 446 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT--------- 496
Query: 124 KEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLW 183
PPP PP A P + K P PA + P + L SP +
Sbjct: 497 ---PPPQAPPPLAAPPLQLAKPPPQAPPA---------------LATPPLQALPSPPASF 538
Query: 184 GSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEER 243
+ F+ S P AP L + P PA + + P
Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL------QVPPSPPASPTLQAPRRPPTP 592
Query: 244 SLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGP-------ASPGLPAEASG 296
D + +G A + P P S +PSS GP ++ P E G
Sbjct: 593 G--PDTSVSGPRLTLALAPGPPP------PPSRSPSSTLSGPDLAGHSSSATSTPEELRG 644
Query: 297 --SGP--GSPHLHPPD-KSSPCHSQLLEAQTPEASQASPCPAVT-PSAPSAALP-DEGSR 349
SGP G+ PPD + + CH P A P P + AP A LP +
Sbjct: 645 YDSGPEGGAAASPPPDAELAACH--------PAAWSRGPAPPLAFRGAPGAPLPWPPATG 696
Query: 350 HTPSPGLPAEGAPEAPRPSSPPPEVLEP 377
+ GL E P ++P P L+P
Sbjct: 697 PGSADGLCTIYETEGPESATPAPGALDP 724
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 73.2 bits (178), Expect = 2e-12
Identities = 217/933 (23%), Positives = 305/933 (32%), Gaps = 148/933 (15%)
Query: 695 SGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQ 754
S G +RG+G+ QSPS G G + + G +G + S F G S
Sbjct: 1595 SPGHGQRGSGSR----QSPSYGRHGS-GSGRSSSSGQHG-SGLGESSGFGHHESSSGQSS 1648
Query: 755 DYGLGGASPRGDPGLGERDWTS-KYGQGAGEGSTREWASRCGIGQEEMEASSSQDQSKVS 813
Y G+ G G+ S + +G GS+ +SR G S S+ S
Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYG-----QHGSGSRQSSGHG 1703
Query: 814 APGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSL 873
G + Q G+ G S + S+G Y SR FG+ +S
Sbjct: 1704 RQGSGSGQSPSRGRHGS-GLGHSSSHGQHGSGSGRSSSRGPYESRSGH--SSVFGQHESG 1760
Query: 874 GTYSSR--DVSLGDWEFGKRDSLGAYASQDA--NEQGQDLGKRDHHGRYSSQDADEQDWE 929
+SS G F + G+ + Q + +++G G+ HG++ S + +
Sbjct: 1761 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG 1820
Query: 930 FQK----RDVSLGTYGSRAAEPQE--QEFGKSAWIRDYSSGGSSRTLDAQDRSFGTRPLS 983
Q + S G +GS + Q S W SS G + Q FG S
Sbjct: 1821 QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS---SSSGRHGSGSGQSSGFGHHESS 1877
Query: 984 SGFSPEEAQQ------------------QDEEFEKKIPSVEDSL-----GEGSRDAGRPG 1020
S S Q Q E+ S S G GSR + G
Sbjct: 1878 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937
Query: 1021 ERGSGGLFSPSTAHVPDGA-LGQRDQ-------SSWQNSDASQEVG-------GHQERQQ 1065
+ GSG SPS + G+ GQ S W +S E G GH+E +
Sbjct: 1938 QHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS 1997
Query: 1066 AGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFG 1125
+ G G G G G S + S GQ S S +S +G
Sbjct: 1998 GQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSS-SHGQHGSGSSQSSGYG 2056
Query: 1126 IIGN---------DRVSGAGFSPSSKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCV 1176
G+ R SG+ SPS G + + G + E SS
Sbjct: 2057 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQ 2116
Query: 1177 GSG----GSSEARESAVGQMGWSGGLSLRDMNLTGCLESGGSEEPGGIGVGEKDWTSDVN 1232
S GS S GQ G G S R SG S G G G +
Sbjct: 2117 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS--SSGSSSRYGQHGSGSR------- 2167
Query: 1233 VKSKDLAEVGEGGGHSQAR---ESGVGQTDWSGVEAGEFLKSRERGVGQADWTPDLGLRN 1289
+S G G GHS +R SG G + G +S RG ++
Sbjct: 2168 -QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYES---------- 2216
Query: 1290 MAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDPDSGG----SQGLRGCGVGQMDWT 1345
G S G + G++ SG SQG G GQ
Sbjct: 2217 -------RSGHSSVFGQHESGSGHS------SAYSQHGSGSGHFCSQGQHGSTSGQ---- 2259
Query: 1346 QDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEARE-LGVGET 1404
Q G S +HG G SQ G + +GS + P R G G +
Sbjct: 2260 SSTFDQEGSSTGQSSSHGQHG-SGSSQSSSYGQQGSGS------GQSPSRGRHGSGSGHS 2312
Query: 1405 S--GPETQGEDYSSSSLEPHPADPGMETG----EALSFGASPGRCPARPPPSGSQGLLEE 1458
S G G +SSSS H + G +G E+ S+ +S SG E+
Sbjct: 2313 SSYGQHGSGSGWSSSS-GRHGSGSGQSSGFGHHESSSWQSS--GYTQHGSGSGHSSSYEQ 2369
Query: 1459 MLAASSSKAVARRESAASGLGGLLEEEGAGA----GAAQEEVLEPGRDSPPSWRPQPDGE 1514
+ S + R ++SG + G+G+ G Q G PS G
Sbjct: 2370 HGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQH---GSGSGQSPSPSRGRHGS 2426
Query: 1515 ASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQG 1547
S +GS + S +GP ++ S G
Sbjct: 2427 GSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSG 2459
Score = 70.1 bits (170), Expect = 2e-11
Identities = 186/781 (23%), Positives = 265/781 (33%), Gaps = 116/781 (14%)
Query: 848 KRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWE-----FGKRDSLGAYASQD- 901
+RD G ++S Q +G+++S SS G +G+ S +S +
Sbjct: 162 QRDFSGQHNSYSG--QSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSND 219
Query: 902 --ANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIR 959
+ GQ G H Q G +GSR+ + E R
Sbjct: 220 THGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGE-------R 272
Query: 960 DYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRP 1019
SS GSS + Q S + L G ++Q G GS +
Sbjct: 273 HRSSSGSSSSY-GQHGSGSRQSLGHGRQGSGSRQSPSHVRH---------GSGSGHSSSH 322
Query: 1020 GERGSGGLFSPSTAHVPDGA-----LGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSA 1074
G+ GSG +S S H G+ GQ + S Q+S S+ G G G S
Sbjct: 323 GQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSG 382
Query: 1075 DLEDGEMGKRGWVGEFSLSVGPQREAA-FSPGQQDWSRDFCIEASERSYQFGIIGNDRVS 1133
+ G+ G S S G A+ S G+ S S +S G R S
Sbjct: 383 --QASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHS-----SGSGQSPGHG----QRGS 431
Query: 1134 GAGFSPSSKMEG---GHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSG----GSSEARE 1186
G+G SPSS G G G +GS G + E SS SG GS
Sbjct: 432 GSGQSPSSGQHGTGFGRSSSSGPYVSGS---GYSSGFGHHESSSEHSSGYTQHGSGSGHS 488
Query: 1187 SAVGQMGWSGGLSLRDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGG 1246
S GQ G G S R +G S G G G + +S + G G G
Sbjct: 489 SGHGQHGSRSGQSSRGERQGS--SAGSSSSYGQHGSGSR--------QSLGHSRHGSGSG 538
Query: 1247 HSQA-----RESGVGQTDWSGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGES 1301
S + ESG Q+ G +S RG ++ GL + + G+S
Sbjct: 539 QSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRS----GQS 594
Query: 1302 KELGVGQMDWGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSE 1361
G GQ G++ G + G G GQ Q+ G S
Sbjct: 595 S--GYGQ--HGSSSG-----------HSSTHGQHGSTSGQ----SSSCGQHGATSGQSSS 635
Query: 1362 AREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEP 1421
+HG G SQ G + +GS G + G + G G +SSS+ P
Sbjct: 636 HGQHG-SGSSQSSRYGQQGSGS---GQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSN-GP 690
Query: 1422 HPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGL 1481
H G +G++ FG G SG + + SS + R+ + SG
Sbjct: 691 H----GSVSGQSSGFGHKSG--------SGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSR 738
Query: 1482 LEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGP--AQ 1539
E+ G+ +G + + G S S G S GSS+ S G +
Sbjct: 739 SEQHGSSSGLS-SSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSG 797
Query: 1540 TSRRPSQGPPARSPSQDFSFIEDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEA 1599
TS S G Q F + +S + + G GH + R G T G S +
Sbjct: 798 TSCSSSCGHYESGSGQASGFGQH----ESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853
Query: 1600 A 1600
+
Sbjct: 854 S 854
Score = 62.8 bits (151), Expect = 3e-09
Identities = 154/650 (23%), Positives = 217/650 (33%), Gaps = 101/650 (15%)
Query: 695 SGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQ 754
S G +RG+G+ QSPS G G + + G G + S F G S
Sbjct: 2065 SPGHGQRGSGSR----QSPSYGRHGS-GSGRSSSSGQHG-PGLGESSGFGHHESSSGQSS 2118
Query: 755 DYGLGGASPRGDPGLGERDWTS-KYGQGAGEGSTREWASRCGIGQEEMEASSSQDQSKVS 813
Y G+ G G+ S + +G GS+ +SR G S S+ S
Sbjct: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYG-----QHGSGSRQSSGHG 2173
Query: 814 APGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSL 873
G + G+ G+ S + S+G Y SR FG+ +S
Sbjct: 2174 RQGSGSGHSPSRGRHGS-GSGHSSSHGQHGSGSGRSSSRGPYESRSGH--SSVFGQHESG 2230
Query: 874 GTYSSR--DVSLGDWEFGKRDSLGAYASQDA--NEQGQDLGKRDHHGRYSSQDADEQDWE 929
+SS G F + G+ + Q + +++G G+ HG++ S + +
Sbjct: 2231 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG 2290
Query: 930 FQK----RDVSLGTYGSRAAEPQE--QEFGKSAWIRDYSSGGSSRTLDAQDRSFGTRPLS 983
Q + S G +GS + Q S W SS G + Q FG S
Sbjct: 2291 QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS---SSSGRHGSGSGQSSGFGHHESS 2347
Query: 984 SGFSPEEAQQ------------------QDEEFEKKIPSVEDSL-----GEGSRDAGRPG 1020
S S Q Q E+ S S G GSR + G
Sbjct: 2348 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407
Query: 1021 ERGSGGLFSPSTAHVPDGA-LGQRDQ-------SSWQNSDASQEVG-------GHQERQQ 1065
+ GSG SPS + G+ GQ S W +S E G GH+E +
Sbjct: 2408 QHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS 2467
Query: 1066 AGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFG 1125
+ G G G G G S + S GQ S S +S +G
Sbjct: 2468 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS-SHGQHGSGSSQSSGYG 2526
Query: 1126 IIGNDRVSGAGFSP----------SSKMEGGHFVPPGKTTAGSVDWT---DQLGLRNLEV 1172
G SG+G SP S G H G++++ + + G + E
Sbjct: 2527 RQG----SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 2582
Query: 1173 SSCVGSG----GSSEARESAVGQMGWSGGLSLRDMNLTGCLESGGSEEPGGIGVGEKDWT 1228
SS S GS S GQ G G S R SG S G G G +
Sbjct: 2583 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS--SSGSSSHYGQHGSGSR--- 2637
Query: 1229 SDVNVKSKDLAEVGEGGGHSQAR---ESGVGQTDWSGVEAGEFLKSRERG 1275
+S G G G S +R SG+G + G +S RG
Sbjct: 2638 -----QSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 2682
Score = 62.0 bits (149), Expect = 5e-09
Identities = 202/874 (23%), Positives = 288/874 (32%), Gaps = 121/874 (13%)
Query: 735 TGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQGAGE-GSTREWASR 793
+G Q SS+ P + G S G + GLG ++ S G G+ GS+ +S
Sbjct: 550 SGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSST 609
Query: 794 CGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQG 853
G S+S S G + Q G+ G+ +S Q + S+G
Sbjct: 610 HG-----QHGSTSGQSSSCGQHGATSGQSSSHGQHGS-GSSQSSRYGQQGSGSGQSPSRG 663
Query: 854 TYSSRDAELQDQEFGKRDSLGTYSS-----------RDVSLGDWEFGKRDSLGAYA--SQ 900
+ S +FG S G + S VS FG + G + SQ
Sbjct: 664 RHGS--------DFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQ 715
Query: 901 DANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEP-----QEQEFGKS 955
+ G R H R EQ S G +GS + + Q G S
Sbjct: 716 HGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHS 775
Query: 956 -AWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEG-S 1013
+ +R SS G S + GT SS E Q F + E G+G S
Sbjct: 776 PSRVRHGSSSGHSSS--HGQHGSGTSCSSSCGHYESGSGQASGFGQH----ESGSGQGYS 829
Query: 1014 RDAGRPGERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGS 1073
+ G S G ++ + GQ D SS Q+S Q G G GS
Sbjct: 830 QHGSASGHFSSQGRHGSTSGQ--SSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGS 887
Query: 1074 ADLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVS 1133
+ G+RG S S G S RS G G+
Sbjct: 888 G--QSPGHGQRGSGSGQSPSYGRHG-----------------SGSGRSSSSGRHGSGSGQ 928
Query: 1134 GAGFS-PSSKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQM 1192
+GF SS + + G + S + +Q G R+ + SS GSS S+ GQ
Sbjct: 929 SSGFGHKSSSGQSSGYTQHGSGSGHSSSY-EQHGSRSGQ-SSRSEQHGSSSGSSSSYGQH 986
Query: 1193 GWSGGLSLRDMNLTGCLESGGSEEPG------GIGVGEKDWTSDVNVKSKDLAEVG---E 1243
G SL G SG + P G G G+ S + G
Sbjct: 987 GSGSRQSLGH----GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYES 1042
Query: 1244 GGGHSQA---RESGVGQTDWSGVEAGEFLKSRERGV--GQADWTPDLGLRNMAPGAVCSP 1298
G GHS RES GQ+ G S G + + G + G S
Sbjct: 1043 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 1102
Query: 1299 GE-----SKELGVGQMDWGNNL----GLRDLEVTCDPDSG---------GSQGLRGCGVG 1340
G+ S+ G G+ G+ G R P G S G G G+G
Sbjct: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG 1162
Query: 1341 QMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEARELG 1400
+ + G S +HG G G +GS S G +R G
Sbjct: 1163 ESSG----FGHHESSSGQSSSYSQHGSGSGH---SSGYGQHGSRS-GQSSRGERHGSSSG 1214
Query: 1401 VGETSGPETQGEDYSS-----SSLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGL 1455
G G SS S H G G L +S G+ + S S+G
Sbjct: 1215 SSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRH-GSGLGHSSSHGQHGSGSGRSSSRGP 1273
Query: 1456 LEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEA 1515
E + S +V + + SG + G+G+G + + G S S +G +
Sbjct: 1274 YE---SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQG-QHGSTSGQSSTFDQEGSS 1329
Query: 1516 SQTEDVDGTWGSSAARWSDQG--PAQTSRRPSQG 1547
+ G GS +++ S G A + + PS+G
Sbjct: 1330 TGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRG 1363
Score = 60.1 bits (144), Expect = 2e-08
Identities = 214/941 (22%), Positives = 307/941 (32%), Gaps = 164/941 (17%)
Query: 695 SGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQ 754
S G +RG+G+ QSPS G G + + G +G + S F G S
Sbjct: 1125 SPGHGQRGSGSR----QSPSYGRHGS-GSGRSSSSGQHG-SGLGESSGFGHHESSSGQSS 1178
Query: 755 DYGLGGASPRGDPGLGE---RDWTSKYGQ--GAGEGSTREWASRCGIGQEEMEASSSQDQ 809
Y G+ G G+ R S G+ G+ GS+ + G G + Q
Sbjct: 1179 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQH-GSGSRQSSGHGRQGS 1237
Query: 810 SKVSAPGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTYSSRDAELQDQEFGK 869
+P +G + G S + S+G Y SR FG+
Sbjct: 1238 GSGHSPS-RGRHGSGLGHSSSHGQHGSGSG--------RSSSRGPYESRSGH--SSVFGQ 1286
Query: 870 RDSLGTYSSR--DVSLGDWEFGKRDSLGAYASQDA--NEQGQDLGKRDHHGRYSSQDADE 925
+S +SS G F + G+ + Q + +++G G+ +G S +
Sbjct: 1287 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQS 1346
Query: 926 QDW----EFQKRDVSLGTYGSRAAEPQE--QEFGKSAWIRDYSSGGSSRTLDAQDRSFGT 979
+ + S G +GS + Q S W SS G + Q FG
Sbjct: 1347 SGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS---SSSGRHGSGSGQSSGFGH 1403
Query: 980 RPLSS-------------GFSPEEAQQ-----QDEEFEKKIPSVEDSL-----GEGSRDA 1016
SS G S Q Q E+ S S G GSR +
Sbjct: 1404 HESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 1463
Query: 1017 GRPGERGSGGLFSPSTAHVPDGA-LGQRDQ-------SSWQNSDASQEVG-------GHQ 1061
G+ GSG SPS + G+ GQ S W +S E G GH+
Sbjct: 1464 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHR 1523
Query: 1062 ERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERS 1121
E + + G G G G G S + S GQ S S +S
Sbjct: 1524 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS-SHGQHGSGSSQS 1582
Query: 1122 YQFGIIGNDRVSGAGFSP----------SSKMEGGHFVPPGKTTAGSVDWT---DQLGLR 1168
+G G SG+G SP S G H G++++ + + G
Sbjct: 1583 SGYGRQG----SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1638
Query: 1169 NLEVSSCVGSG----GSSEARESAVGQMGWSGGLSLRDMNLTGCLESGGSEEPGGIGVGE 1224
+ E SS S GS S GQ G G S R S S G G G
Sbjct: 1639 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS--SSRSSSRYGQHGSGS 1696
Query: 1225 KDWTSDVNVKSKDLAEVGEGGGHSQAR---ESGVGQTDWSGVEAGEFLKSRERGVGQADW 1281
+ +S G G G S +R SG+G + G +S RG ++
Sbjct: 1697 R--------QSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYES-- 1746
Query: 1282 TPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDPDSGG----SQGLRGC 1337
G S G + G++ SG SQG G
Sbjct: 1747 ---------------RSGHSSVFGQHESGSGHS------SAYSQHGSGSGHFCSQGQHGS 1785
Query: 1338 GVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEAR 1397
GQ Q G S +HG G SQ G + +GS + P R
Sbjct: 1786 TSGQ----SSTFDQEGSSTGQSSSHGQHG-SGSSQSSSYGQQGSGS------GQSPSRGR 1834
Query: 1398 E-LGVGETS--GPETQGEDYSSSSLEPHPADPGMETG----EALSFGASPGRCPARPPPS 1450
G G +S G G +SSSS H + G +G E+ S+ +S S
Sbjct: 1835 HGSGSGHSSSYGQHGSGSGWSSSS-GRHGSGSGQSSGFGHHESSSWQSS--GYTQHGSGS 1891
Query: 1451 GSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGA----GAAQEEVLEPGRDSPPS 1506
G E+ + S + + ++SG + G+G+ G Q G PS
Sbjct: 1892 GHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQH---GSGSGQSPS 1948
Query: 1507 WRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQG 1547
G S G +GS + S +GP ++ S G
Sbjct: 1949 PSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSG 1989
Score = 58.5 bits (140), Expect = 5e-08
Identities = 198/949 (20%), Positives = 309/949 (32%), Gaps = 138/949 (14%)
Query: 739 QPSSFSPSSWCQGASQDY--GLGGASPRGDPGLG-----ERDWTSKYGQGAGEGST---R 788
Q SSFS SSW G + Y + G+ G + +RD++ ++ +G+ S+ +
Sbjct: 123 QESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQ 182
Query: 789 EWASRCGIGQEEMEASSSQDQS---KVSAPGVLTAQD-RVVGKPAQLGTQRSQEADVQDW 844
S G+ + + S Q + S G ++ D G G + + + Q
Sbjct: 183 NSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSS 242
Query: 845 EFRKRDS-------QGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAY 897
+ + S G + SR + E R S G+ S S G G R SLG
Sbjct: 243 GYSQHGSGSGHSSGYGQHGSRSGQSSRGE-RHRSSSGSSS----SYGQHGSGSRQSLGHG 297
Query: 898 ASQDANEQ-------GQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQ 950
+ Q G G HG++ S + + + + G+ + E
Sbjct: 298 RQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSS----YSYSRGHYESGSGQTSGFGQHES 353
Query: 951 EFGKSAWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLG 1010
G+S+ + SG + Q S + SSG + +Q + + + S G
Sbjct: 354 GSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSG-QHGSSSRQSSSYGQHESASRHSSG 412
Query: 1011 EGSRDAGR-----PGERGSGGLFSPSTAHVPDG------------------ALGQRDQSS 1047
G +G G+RGSG SPS+ G G + SS
Sbjct: 413 RGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSS 472
Query: 1048 WQNSDASQEVGGHQERQQAGAQGPGSADLEDGE-----MGKRGWVGEFS----LSVGPQR 1098
+S +Q G G G S GE G G+ S+G R
Sbjct: 473 EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSR 532
Query: 1099 EAAFSPGQQDWSRDFCIEASERSYQFG---------------IIGNDRVSGAGFSPSSKM 1143
+ S SR S +S +G G+ SG G S
Sbjct: 533 HGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSG 592
Query: 1144 EGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSLR-D 1202
+ + G +++G Q G + + SSC G G++ + S+ GQ G S R
Sbjct: 593 QSSGYGQHG-SSSGHSSTHGQHGSTSGQSSSC-GQHGATSGQSSSHGQHGSGSSQSSRYG 650
Query: 1203 MNLTGCLES----------GGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGH--SQA 1250
+G +S G S G G G W+S N ++ G GH
Sbjct: 651 QQGSGSGQSPSRGRHGSDFGHSSSYGQHGSG-SGWSSS-NGPHGSVSGQSSGFGHKSGSG 708
Query: 1251 RESGVGQTDWSGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMD 1310
+ SG Q + + K R GQ+ + G + + G G
Sbjct: 709 QSSGYSQHGSGSSHSSGYRKHGSRS-GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGR 767
Query: 1311 WGNNLGLRDLEVTCDPDSG--GSQGLRGCGVG-------QMDWTQDLAPQNVELFGAPSE 1361
G+ G V SG S G G G + + G+
Sbjct: 768 QGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQG 827
Query: 1362 AREHG--VGGVSQCPEPGLRHNGSLSPGLEARDPLEARELGVGETSGPET--QGEDYSSS 1417
+HG G S G S S G ++ G E++ +G S S
Sbjct: 828 YSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGS 887
Query: 1418 SLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASG 1477
P G +G++ S+G G R SG G + S + S+
Sbjct: 888 GQSPGHGQRGSGSGQSPSYGRH-GSGSGRSSSSGRHG-----SGSGQSSGFGHKSSSGQS 941
Query: 1478 LGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGP 1537
G G+G ++ E + G S S R + G +S + G GS + + G
Sbjct: 942 SGYTQHGSGSGHSSSYE---QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQ 998
Query: 1538 ----AQTSRRPSQGPPARSPSQDFSFIEDTEILDSAMYRSRANLGRKRG 1582
+ S PS+G Q S+ YRS + RG
Sbjct: 999 HGSGSGQSPSPSRGRHGSGSGQSSSY---------GPYRSGSGWSSSRG 1038
Score = 55.1 bits (131), Expect = 6e-07
Identities = 197/866 (22%), Positives = 272/866 (31%), Gaps = 139/866 (16%)
Query: 711 QSPSTCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLG 770
QSPS G S S +G G S S + Q G G S G G
Sbjct: 658 QSPSRGRHG----SDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS-----GSG 708
Query: 771 ERDWTSKYGQGAGEGST-REWASRCG-IGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKP 828
+ S++G G+ S R+ SR G + E SSS S G + Q G+
Sbjct: 709 QSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQ 768
Query: 829 AQLGTQRSQEADVQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEF 888
G+ S R S G SS G+ +S S G +E
Sbjct: 769 GS-GSGHSPS------RVRHGSSSGHSSSHGQH------------GSGTSCSSSCGHYES 809
Query: 889 GKRDSLG-----AYASQDANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSR 943
G + G + + Q ++ G G GR+ S S G + S
Sbjct: 810 GSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSS---------SSGQHDSS 860
Query: 944 AAEPQEQEFGKSAWIRDYSSG-GSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKI 1002
+ Q +G+ ++SG G + Q G R SG SP +
Sbjct: 861 SG--QSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRS-- 916
Query: 1003 PSVEDSLGEGSRDAGRPGERGSGGLFSPSTAHVPDGALG-----------------QRDQ 1045
S G GS + G + S G S T H Q
Sbjct: 917 -SSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGS 975
Query: 1046 SSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPG 1105
SS +S Q G ++ G G GS G+ G S S GP R +
Sbjct: 976 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGS---- 1031
Query: 1106 QQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPSSKMEGGHFVPPGKTTAGSVDWTDQL 1165
WS +S Y+ G+ SG G S + + G ++
Sbjct: 1032 --GWS------SSRGPYE---SGSGHSSGLGHRESRSGQSSGYGQHGSSSGH-------- 1072
Query: 1166 GLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSLRDMNLTGCLESGGSEEPG----GIG 1221
SS G GS+ + S+ GQ G S G S + G SG S+ G G G
Sbjct: 1073 -------SSTHGQHGSTSGQSSSCGQHGASSGQS----SSHGQHGSGSSQSSGYGRQGSG 1121
Query: 1222 VGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDWSGVEAGEFLKSRERGVGQADW 1281
G+ S+ G G S R S GQ SG+ E GQ+
Sbjct: 1122 SGQSPGHGQRGSGSRQSPSYGRHGSGS-GRSSSSGQ-HGSGLGESSGFGHHESSSGQSSS 1179
Query: 1282 TPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQ 1341
G G G GQ + R S G G G Q
Sbjct: 1180 YSQHG-----------SGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 1228
Query: 1342 MDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEARELGV 1401
+ Q +PS R HG G+ G +GS S +R P E+R G
Sbjct: 1229 ---SSGHGRQGSGSGHSPSRGR-HG-SGLGHSSSHG--QHGSGSGRSSSRGPYESRS-GH 1280
Query: 1402 GETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLA 1461
G G + SS+ H + G + G++ G+ S +E +
Sbjct: 1281 SSVFGQHESGSGH-SSAYSQHGSGSGHFCSQG-QHGSTSGQ---------SSTFDQEGSS 1329
Query: 1462 ASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDV 1521
S + R S +S G GAG+G + G S S G S
Sbjct: 1330 TGQSSSYGHRGSGSSQSSG-YGRHGAGSGQSPSRG-RHGSGSGHSSSYGQHGSGSGWSSS 1387
Query: 1522 DGTWGSSAARWSDQGPAQTSRRPSQG 1547
G GS + + S G ++S S G
Sbjct: 1388 SGRHGSGSGQSSGFGHHESSSWQSSG 1413
Score = 54.7 bits (130), Expect = 8e-07
Identities = 188/875 (21%), Positives = 277/875 (31%), Gaps = 111/875 (12%)
Query: 722 GWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQG 781
G Q S+ G +G SS G + G G+S R G+ + S++ G
Sbjct: 354 GSGQSSGYSKHG-SGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSG 412
Query: 782 AGEGSTREWASRCGIGQEEMEA--SSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEA 839
G+ S+ S G GQ + S S Q ++ V G G + +
Sbjct: 413 RGQHSSGSGQSP-GHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESS 471
Query: 840 DVQDWEFRKRDSQGTYSSRDAE--LQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAY 897
+ + S +SS + + + + + G+ + S G G R SLG
Sbjct: 472 SEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG-- 529
Query: 898 ASQDANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAW 957
+ G G+ R + Q + G SR P E G S+
Sbjct: 530 ----HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG--PYESGSGHSSG 583
Query: 958 IRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKI----------PSVED 1007
+ G + Q +G SSG S Q + S
Sbjct: 584 L------GHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHG 637
Query: 1008 SLGEGSRDAGRPGERGSGGLFSPSTA-HVPD----GALGQRDQ-SSWQNSD------ASQ 1055
G GS + R G++GSG SPS H D + GQ S W +S+ + Q
Sbjct: 638 QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQ 697
Query: 1056 EVG-GHQ--ERQQAGAQGPGSADLEDG---EMGKRGWVGEFSLSVGPQREAAFSPGQQDW 1109
G GH+ Q +G GS + G R S G + S GQ
Sbjct: 698 SSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG- 756
Query: 1110 SRDFCIEASERSYQFGIIGNDRVSGAGFSPSSKMEG---GHFVPPGKTTAGSVDWTDQLG 1166
S +S G G SG+G SPS G GH G+ +G+
Sbjct: 757 ------SGSHQSSGHGRQG----SGSGHSPSRVRHGSSSGHSSSHGQHGSGT-------- 798
Query: 1167 LRNLEVSSCVGSGGSSEARESAVGQ-MGWSGGLSLRDMNLTGCLESGGSEEPGGIGVGEK 1225
SS G S + S GQ SG + + +G S G G G+
Sbjct: 799 ----SCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRH---GSTSGQS 851
Query: 1226 DWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDWSGVEAGEFLKSRERGVGQADWTPDL 1285
+ + S + G+ H A G+ G +G+ +RG G +P
Sbjct: 852 SSSGQHDSSSGQSSSYGQ---HESASHHASGR-GRHGSGSGQSPGHGQRGSGSGQ-SPSY 906
Query: 1286 GLRNMAPGAVCSPGESKELGVGQMD-WGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQMDW 1344
G G S G G GQ +G+ SG G
Sbjct: 907 GRHGSGSGRSSSSGRHGS-GSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSG 965
Query: 1345 TQDLAPQNVELFGAPSEAREHGVG------------GVSQCPEPGLRHNGSLSPGLEARD 1392
+ Q+ G+ S +HG G G Q P P +GS S +
Sbjct: 966 QSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1025
Query: 1393 PLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASPGRCPARPPPSGS 1452
P + G + GP G + SS L + G +G G+S G G
Sbjct: 1026 PYRSGS-GWSSSRGPYESGSGH-SSGLGHRESRSGQSSGYG-QHGSSSGHSSTH----GQ 1078
Query: 1453 QGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPD 1512
G ++ + +S++ G G + +G G G S S
Sbjct: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG-------RQGSGSGQSPGHGQR 1131
Query: 1513 GEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQG 1547
G S+ G GS + R S G + S G
Sbjct: 1132 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG 1166
Score = 44.7 bits (104), Expect = 8e-04
Identities = 135/606 (22%), Positives = 187/606 (30%), Gaps = 91/606 (15%)
Query: 989 EEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPG--ERGSGGLFSPSTAHVPDGALGQRDQS 1046
+E Q++ E+ E K E S S AG R G P T + QRD S
Sbjct: 109 QEEQEETEKEENK--RQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFS 166
Query: 1047 SWQNSDASQEVG-GHQERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPG 1105
NS + Q G Q + G G G+ G G S G
Sbjct: 167 GQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSG 226
Query: 1106 QQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPSSKMEGGHFVPPG-----KTTAGSVD 1160
Q S F S G + SG+G S G ++++GS
Sbjct: 227 Q---SSGFSQHKSSSGQSSGY--SQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSS 281
Query: 1161 WTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSLRDMNLTGCLES-------GG 1213
Q G + + G S S V SG S + +G S G
Sbjct: 282 SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341
Query: 1214 SEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQAR---ESGVGQTDWSGVEAGEFLK 1270
S + G G E + +S ++ G G GHS ++ S GQ SG +
Sbjct: 342 SGQTSGFGQHESG-----SGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQ 396
Query: 1271 SRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDPDSGG 1330
S G ++ G + G+ SPG GQ G+
Sbjct: 397 SSSYGQHESASRHSSGRGQHSSGSGQSPGH------GQRGSGSG-------------QSP 437
Query: 1331 SQGLRGCGVGQMDWTQDLAPQN--VELFGAPSEAREHGVG----GVSQCPEPGLRHNGSL 1384
S G G G G+ + + FG + EH G G G +GS
Sbjct: 438 SSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSR 497
Query: 1385 SPGLEARDPLEARELGVGETSGPETQGEDY--------SSSSLEPHPADPGMETGEALSF 1436
S G +R + G + G G S S P P+ E+G S
Sbjct: 498 S-GQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSS 556
Query: 1437 GASP-----GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGA 1491
P GR +R P G +SGLG G +G
Sbjct: 557 SYGPHGYGSGRSSSRGPYESGSG-------------------HSSGLGHQESRSGQSSGY 597
Query: 1492 AQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWS-DQGPAQTSRRPSQGP-P 1549
Q G S G++S T G S++ G +Q+SR QG
Sbjct: 598 GQHG-SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGS 656
Query: 1550 ARSPSQ 1555
+SPS+
Sbjct: 657 GQSPSR 662
Score = 41.2 bits (95), Expect = 0.009
Identities = 95/396 (23%), Positives = 133/396 (33%), Gaps = 49/396 (12%)
Query: 741 SSFSPSSWCQ---GASQDYGLG------GASP-----RGDPGLGERDWTSKYGQGAGEGS 786
SS S SS+ Q G+ Q G G G SP R G G+ S YG G+G S
Sbjct: 2386 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSS 2445
Query: 787 TR---EWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQ--EADV 841
+R E S G E+ S Q S G + G+ Q S +
Sbjct: 2446 SRGPYESGSGHSSGLGHRESRSGQS-SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 2504
Query: 842 QDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQD 901
+ G+ SS+ + Q G S G S +G+ S G+ S
Sbjct: 2505 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS-GSGRSSS 2563
Query: 902 ANEQGQDLGKRD---HHGRYSSQDAD-EQDWEFQKRDVSLGTYGSRAAEPQ--EQEFGKS 955
+ + G LG+ HH S Q + Q G +GSR+ + E+ S
Sbjct: 2564 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSS 2623
Query: 956 AWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRD 1015
Y GS Q G + SG SP + S G G
Sbjct: 2624 GSSSHYGQHGSG---SRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS-GSGRSS 2679
Query: 1016 AGRP-----------GERGSGGLFSPSTAHVPDGA-----LGQRDQSSWQNSDASQEVGG 1059
+ P G+ SG S + + G+ GQ +S Q+S QE
Sbjct: 2680 SRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS 2739
Query: 1060 HQERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVG 1095
+ G +G GS+ + G+ G SLS G
Sbjct: 2740 TGQSSSYGHRGSGSS--QSSGYGRHGAGSGQSLSHG 2773
Score = 32.3 bits (72), Expect = 4.1
Identities = 35/140 (25%), Positives = 52/140 (37%), Gaps = 8/140 (5%)
Query: 422 SLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFP 481
SL + G QSPS + + G GQ S + P+G+ S WS S+ +
Sbjct: 1463 SLGHGQHGSGSGQSPSPSRGRHGSG-----SGQSSSYS---PYGSGSGWSSSRGPYESGS 1514
Query: 482 TRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSS 541
+ SGLG S S + ++ + S+ + S GA S S S
Sbjct: 1515 SHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1574
Query: 542 WVQGDDPSMSLTQKGDGESQ 561
G S ++G G Q
Sbjct: 1575 HGSGSSQSSGYGRQGSGSGQ 1594
Score = 31.2 bits (69), Expect = 9.1
Identities = 35/140 (25%), Positives = 51/140 (36%), Gaps = 8/140 (5%)
Query: 422 SLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFP 481
SL + G QSPS + + G GQ S + P+G+ S WS S+ +
Sbjct: 2403 SLGHGQHGSGSGQSPSPSRGRHGSG-----SGQSSSYS---PYGSGSGWSSSRGPYESGS 2454
Query: 482 TRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSS 541
SGLG S S + ++ + S+ + S GA S S S
Sbjct: 2455 GHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 2514
Query: 542 WVQGDDPSMSLTQKGDGESQ 561
G S ++G G Q
Sbjct: 2515 HGSGSSQSSGYGRQGSGSGQ 2534
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 72.4 bits (176), Expect = 4e-12
Identities = 107/396 (27%), Positives = 143/396 (36%), Gaps = 72/396 (18%)
Query: 1 MKVSTLRE--SSAMASPLPREMEEEL--VPTGSEPGDTRA--KPPVKP-KPRALPAKPAL 53
++VST E S A A P P E VPT EP A PP +P P A P
Sbjct: 992 VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE 1051
Query: 54 PAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEA 113
P P+ VP P P P A +P+ + A P + P A P E T A
Sbjct: 1052 PTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPTPEEPTSPAA 1109
Query: 114 TQETGKEEAGKEE--PPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEE-ILAKMEQ 170
T +E A P P P + AA P P PA A T EE A +
Sbjct: 1110 AVPTPEEPASPAAAVPTPEEPASPAAA------VPTPEEPAFPAPAVPTPEESASAAVAV 1163
Query: 171 PRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPA 230
P E ASP P + ++ + SPA
Sbjct: 1164 PTPEESASP------------------------AAAVPTPAESASFAAVVATLEEPTSPA 1199
Query: 231 ECREEHSKTPEERSLPSDL-AFNGDLAKAASSELPAD----ISKPWIPSSPAPSSENGGP 285
+ P ++ + L F A +SE PA +S P P+SPA +
Sbjct: 1200 ------ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAA------ 1247
Query: 286 ASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVT----PSAPSA 341
+P + + L P + SSP S TPE ASP AV+ P++P+A
Sbjct: 1248 ----VPTLEEPTSSAAAVLTPEELSSPAAS----VPTPE-EPASPAAAVSNLEEPASPAA 1298
Query: 342 ALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEP 377
A+P P+ +P P P + PP E + P
Sbjct: 1299 AVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
Score = 54.3 bits (129), Expect = 1e-06
Identities = 133/626 (21%), Positives = 216/626 (34%), Gaps = 95/626 (15%)
Query: 101 PRPAVEASTGGEATQ-----------ETGKEEAGKEEP------PPLTPPARCAAPGGVR 143
P V +S GGE + E +AG EP P L P+R AA V+
Sbjct: 785 PELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVK 844
Query: 144 KAPAPFRPASER---FAATTVEE----ILAKMEQPRKEVL-----------------ASP 179
A P+ E AA E + A + P +++L ++P
Sbjct: 845 DALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAP 904
Query: 180 DRLWGSRLTFN-HDGSSRYGPRTYGTTTAPR-----DEDGSTLFRGWSQEGPVKSPAECR 233
+R +T + +G++ + TAP ++G + G+S E +
Sbjct: 905 ERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPI 964
Query: 234 EEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPA---PSSENGGPASPGL 290
E TPE P+ + A+ +S P P+SPA P+ E + +
Sbjct: 965 TEEDGTPEGPVTPATTVHAPEEPDTAAVR----VSTPEEPASPAAAVPTPEEPTSPAAAV 1020
Query: 291 PAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRH 350
P + P + P + +SP + + + A P P P++P+AA+P
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPTSPAAAVPTPEEPT 1079
Query: 351 TPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEE 410
+P+ +P P +P + P PE EP S P A P P E P+ E
Sbjct: 1080 SPAAAVPTPEEPTSPAAAVPTPE--EPTS---PAAAVPTP----EEPASPAAAVPT--PE 1128
Query: 411 EAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNW 470
E A PT + F + +P +E ++A + + A P AES
Sbjct: 1129 EPASPAAAVPTP-EEPAFPAPAVPTP---EESASAAVAVPTPEESASPAAAVPTPAESAS 1184
Query: 471 SLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQG 530
+ PT P+ + P+P + E +S E
Sbjct: 1185 FAAVVATLEEPTSPA--------ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVS 1236
Query: 531 AGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERY 590
P+ ++ ++P T P+ + P +PT E P P
Sbjct: 1237 NPEEPTSPAAAVPTLEEP----TSSAAAVLTPEELSSPAASVPTPE-EPASPAAAVSNLE 1291
Query: 591 ESQEPLAGQESPLPLATREAALPILE-PVLGQEQPAAPDQPC-------VLFADAPEPGQ 642
E P A +P A A++P E P + PAA P V F
Sbjct: 1292 EPASPAAAVPTPEVAAIPAASVPTPEVPAI----PAAAVPPMEEVSPIGVPFLGVSAHTD 1347
Query: 643 ALPVEEEAVTLARAETTQARTEAQDL 668
++P+ EE + ++ +DL
Sbjct: 1348 SVPISEEGTPVLEEASSTGMWIKEDL 1373
Score = 41.2 bits (95), Expect = 0.009
Identities = 58/241 (24%), Positives = 85/241 (35%), Gaps = 28/241 (11%)
Query: 493 DSPPPSPITEAS--EAAEAAEAGNLAVSSREEGVS---------QQGQGAGSAPSGSG-S 540
D P P+T A+ A E + + VS+ EE S + A + P+ +
Sbjct: 968 DGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPT 1027
Query: 541 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE 600
S P T P+ P P +PT E P P E P A
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPTSPAAAVPTPEEPTSPAAAVP 1086
Query: 601 SPLPLATREAALPILEP-------VLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTL 653
+P + AA+P E V E+PA+P + P A+P EE
Sbjct: 1087 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP 1146
Query: 654 ARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSP 713
A A T ++ A+ P PE S+ A P P+ + A L++ SP
Sbjct: 1147 APAVPT-----PEESASAAVAVPTPEESA---SPAAAVPTPAESASFAAVVATLEEPTSP 1198
Query: 714 S 714
+
Sbjct: 1199 A 1199
Score = 34.7 bits (78), Expect = 0.83
Identities = 34/128 (26%), Positives = 50/128 (39%), Gaps = 8/128 (6%)
Query: 562 PQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILE-PVLG 620
P+ P P +PT E P P E P A +P A+ AA+P E P
Sbjct: 1075 PEEPTSPAAAVPTPE-EPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASP 1133
Query: 621 QEQPAAPDQPCVLFADAPEPGQ------ALPVEEEAVTLARAETTQARTEAQDLCRASPE 674
P++P P P + A+P EE+ + A A T A + + A+ E
Sbjct: 1134 AAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE 1193
Query: 675 PPGPESSS 682
P ++S
Sbjct: 1194 EPTSPAAS 1201
Score = 34.3 bits (77), Expect = 1.1
Identities = 40/172 (23%), Positives = 64/172 (37%), Gaps = 20/172 (11%)
Query: 562 PQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALP-------I 614
P+ PA P +PT E P P ES +P A+ AA+P
Sbjct: 1127 PEEPASPAAAVPTPE-EPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASF 1185
Query: 615 LEPVLGQEQPAAP----DQPCVLFADAPE---PGQALPVEEEAVTLARAETTQARTEAQD 667
V E+P +P P + A E P ++P EE +LA A + +
Sbjct: 1186 AAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPA 1245
Query: 668 LCRASPEPPGPESSSRWLDDLLAS-----PPPSGGGARRGAGAELKDTQSPS 714
+ E P +++ + L+S P P + A + L++ SP+
Sbjct: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPA 1297
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 70.5 bits (171), Expect = 1e-11
Identities = 118/506 (23%), Positives = 164/506 (32%), Gaps = 124/506 (24%)
Query: 197 YGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKS--PAECREEHSKTPEERSLPSDLA---- 250
YG + T + E G+ + + P+ + P +E H S+P D A
Sbjct: 53 YGDNRFNTVS----ESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEV 108
Query: 251 ------FNGDLAKAAS--SELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSP 302
NG+L +S P + + P P GPA PG P + S GSP
Sbjct: 109 TGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPP-----GPA-PGPPQDISEPPGGSP 162
Query: 303 HLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAP-----SAALPDEGSRHTPSPGLP 357
PP + P LLE P + P P + +P S ++P P+P L
Sbjct: 163 LPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLA 222
Query: 358 AEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAH 417
P P P+ PP PH++ TR FP GG + K D
Sbjct: 223 FLAPPPPPVPAPAPPAPASPHTVG-------------------TRLFPPGGVTKWKSDVA 263
Query: 418 LRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFE 477
L R S P E G +L P E + + +SF+
Sbjct: 264 LNGRQAEATRAS-----PPRSPAEPKGSALGPNP---------------EPHLTFPRSFK 303
Query: 478 WTFPTRPSGLGVWRLDSPPPSPI-TEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPS 536
PPP+P+ T + EA EA +EEG +++ P
Sbjct: 304 ----------------VPPPTPVRTSSIPVQEAQEA-----PRKEEGATKKAPSRLPLPP 342
Query: 537 GSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPL 596
P + GE + PA P G QA+ER
Sbjct: 343 SFHIRPASQVYPDRAPEPDCPGELKATAPASP---------RLGQSQSQADER------- 386
Query: 597 AGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARA 656
AG P P A P L P PAAP PC A P G
Sbjct: 387 AGTPPPAPPLPPPA--PPLPPPAPPLPPAAPPLPCAQKAAHPPAG--------------- 429
Query: 657 ETTQARTEAQDLCRASPEPPGPESSS 682
T+ + + P PP PE+++
Sbjct: 430 -FTKTPKSSSPALKPKPNPPSPENTA 454
Score = 55.8 bits (133), Expect = 3e-07
Identities = 159/703 (22%), Positives = 234/703 (33%), Gaps = 118/703 (16%)
Query: 6 LRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGP 65
LR S++ P + ++L+ PG P +P P LP+ PS P P
Sbjct: 119 LRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP---PGGSPLPSPPSTAPPPPP 175
Query: 66 ---RPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEA 122
PP P P + L+ P P P
Sbjct: 176 LLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTP------------------------ 211
Query: 123 GKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTV---------EEILAKMEQPRK 173
+ PP P A A P APAP PAS T + + +A + +
Sbjct: 212 -PDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAE 270
Query: 174 EVLASPDRL----WGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSP 229
ASP R GS L N + + PR++ P S++ +QE P K
Sbjct: 271 ATRASPPRSPAEPKGSALGPNPEPHLTF-PRSF-KVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 230 AECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIP---SSPAPSSENGGPA 286
++ S+ P LP + AS P +P P + AP+S G
Sbjct: 329 GATKKAPSRLP----LPPSFHI-----RPASQVYPDRAPEPDCPGELKATAPASPRLG-Q 378
Query: 287 SPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDE 346
S E +G+ P +P L PP P P A P P A AA P
Sbjct: 379 SQSQADERAGTPPPAPPLPPPAPPLP----------PPAPPLPPAAPPLPCAQKAAHPPA 428
Query: 347 GSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPS 406
G TP PA P+P+ P PE ++ P P ++ +L + +
Sbjct: 429 GFTKTPKSSSPA----LKPKPNPPSPE----NTASSAPVDWRDP-SQMEKLRNELAAYLC 479
Query: 407 GGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGA 466
G E + +H RP V + EG ++E +L +LP ++ G
Sbjct: 480 GSRREDRFLSH-RPGPTVAPQSKEGKKGPRLPEKE----TLLSLPAKDTPPGVPEKSLGG 534
Query: 467 ESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPS----------PITEASEAAEAAEAGNLA 516
S + T P+ + DSP PS ++ A+E G+L
Sbjct: 535 SSLTETEAAPSLTLPS----VDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLP 590
Query: 517 VSSREEG--VSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQF---PAVPLEP 571
R EG + + G A S V + P S T QP+ PA+P
Sbjct: 591 PKPRLEGGRICENG-----ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP--- 642
Query: 572 LPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILE---PVLGQEQPAAPD 628
P P +P + + G +PL AT P+ P + P
Sbjct: 643 -PKATPEPAIPPKATLWPATPPKATLGPATPLK-ATSGPTTPLKATSGPAIASTATTLPT 700
Query: 629 QPCVLFAD---APEPGQALPVEEEAVTLARAETTQARTEAQDL 668
L A+ P P +E T ++A + +EA L
Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRL 743
Score = 43.5 bits (101), Expect = 0.002
Identities = 117/497 (23%), Positives = 166/497 (33%), Gaps = 108/497 (21%)
Query: 31 PGDTRAKPPVKPK---------------PRALPAKPALPAKPSLLVPVGPRPPRGPLAEL 75
PG+ +A P P+ P A P P P P P P PP P L
Sbjct: 363 PGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP---PAPPLPPAAP--PL 417
Query: 76 PSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPAR 135
P A+K A P G +K P +P A K +P P +P
Sbjct: 418 PCAQK----AAHPPAGFTKTPKSSSP--------------------ALKPKPNPPSPENT 453
Query: 136 CAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSS 195
++ AP +R S+ ME+ R E+ A L GSR
Sbjct: 454 ASS------APVDWRDPSQ-------------MEKLRNELAA---YLCGSR------RED 485
Query: 196 RYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDL 255
R+ G T AP+ ++G R +E + PA ++ PE+ S L +
Sbjct: 486 RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA--KDTPPGVPEKSLGGSSLT---ET 540
Query: 256 AKAASSELPADISKPWIP-SSPAPS-----SENGGPASPGLPAEAS---GSGPGSPHLH- 305
A S LP S +IP SP PS +E S EA GS P P L
Sbjct: 541 EAAPSLTLP---SVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEG 597
Query: 306 ---------------PPDKSSPCHSQLLEAQTPEASQASPCPAVTPSA-PSAALPDEGSR 349
P K+ P S L T +A PA+ P A P A+P + +
Sbjct: 598 GRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATL 657
Query: 350 HTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGE 409
+P G + +S P L+ S +T+ +L+ + P+G
Sbjct: 658 WPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQP 717
Query: 410 EEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESN 469
E+ P+ + P+Q G G L +P +S
Sbjct: 718 EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQS- 776
Query: 470 WSLSQSFEWTFPTRPSG 486
SLS+ PT G
Sbjct: 777 -SLSREVAVVMPTLARG 792
Score = 37.0 bits (84), Expect = 0.17
Identities = 133/597 (22%), Positives = 186/597 (31%), Gaps = 132/597 (22%)
Query: 13 ASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPP---- 68
A PLP + P G + P +KPKP P P + PV R P
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN-----PPSPENTASSAPVDWRDPSQME 468
Query: 69 --RGPLAEL--PSARKMNMLA-------GPQPYGGSKRP----------LPFAPRP--AV 105
R LA S R+ L+ PQ G K P LP P
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 106 EASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL 165
E S GG + ET E P LT P+ P + +P P +
Sbjct: 529 EKSLGGSSLTET-------EAAPSLTLPSVDYIP---QDSPTPSVRQIRNELEARLSSAA 578
Query: 166 AKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRT------YGTTTAPRDEDGSTLFRG 219
K +P L RL G R+ N + TT P +T +
Sbjct: 579 EKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLP-----TTSLQP 633
Query: 220 WSQEGPVKSPAECREEH--------SKTPEERSLPSDL-------------AFNGDLAKA 258
+ GP P E TP + +L A +G +
Sbjct: 634 KAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIAS 693
Query: 259 ASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHP------------ 306
++ LP S+ P+ + PAS + + G GSP
Sbjct: 694 TATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAA 753
Query: 307 -PDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPS-----AALPDEGSRHTPSPGLPAEG 360
P K+SP ++ P Q+S V P+ AA P E PGLPA
Sbjct: 754 FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPA-- 811
Query: 361 APEAPRPSSPPPEVL-EPHSLDQPPATSPRPLI-----------EVGELLDLTRTFPSGG 408
+ P + P E+L P + + SP L+ VG L R+ G
Sbjct: 812 --KPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALG--RSSLPGS 867
Query: 409 EEEAKGDAHLRPTSLVQRRFSEG---VLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFG 465
+ A S+ + + V+ ++ EK +P G +L D
Sbjct: 868 LRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRD---- 923
Query: 466 AESNWSLSQSFEWTFP--------------TRPSGLGVWRLDSPPPSPITEASEAAE 508
AE LS+ WT P P G + + S PPSP + E E
Sbjct: 924 AEGT-ELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEE 979
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 70.5 bits (171), Expect = 1e-11
Identities = 118/506 (23%), Positives = 164/506 (32%), Gaps = 124/506 (24%)
Query: 197 YGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKS--PAECREEHSKTPEERSLPSDLA---- 250
YG + T + E G+ + + P+ + P +E H S+P D A
Sbjct: 53 YGDNRFNTVS----ESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEV 108
Query: 251 ------FNGDLAKAAS--SELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSP 302
NG+L +S P + + P P GPA PG P + S GSP
Sbjct: 109 TGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPP-----GPA-PGPPQDISEPPGGSP 162
Query: 303 HLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAP-----SAALPDEGSRHTPSPGLP 357
PP + P LLE P + P P + +P S ++P P+P L
Sbjct: 163 LPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLA 222
Query: 358 AEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAH 417
P P P+ PP PH++ TR FP GG + K D
Sbjct: 223 FLAPPPPPVPAPAPPAPASPHTVG-------------------TRLFPPGGVTKWKSDVA 263
Query: 418 LRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFE 477
L R S P E G +L P E + + +SF+
Sbjct: 264 LNGRQAEATRAS-----PPRSPAEPKGSALGPNP---------------EPHLTFPRSFK 303
Query: 478 WTFPTRPSGLGVWRLDSPPPSPI-TEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPS 536
PPP+P+ T + EA EA +EEG +++ P
Sbjct: 304 ----------------VPPPTPVRTSSIPVQEAQEA-----PRKEEGATKKAPSRLPLPP 342
Query: 537 GSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPL 596
P + GE + PA P G QA+ER
Sbjct: 343 SFHIRPASQVYPDRAPEPDCPGELKATAPASP---------RLGQSQSQADER------- 386
Query: 597 AGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARA 656
AG P P A P L P PAAP PC A P G
Sbjct: 387 AGTPPPAPPLPPPA--PPLPPPAPPLPPAAPPLPCAQKAAHPPAG--------------- 429
Query: 657 ETTQARTEAQDLCRASPEPPGPESSS 682
T+ + + P PP PE+++
Sbjct: 430 -FTKTPKSSSPALKPKPNPPSPENTA 454
Score = 55.8 bits (133), Expect = 3e-07
Identities = 159/703 (22%), Positives = 234/703 (33%), Gaps = 118/703 (16%)
Query: 6 LRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGP 65
LR S++ P + ++L+ PG P +P P LP+ PS P P
Sbjct: 119 LRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP---PGGSPLPSPPSTAPPPPP 175
Query: 66 ---RPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEA 122
PP P P + L+ P P P
Sbjct: 176 LLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTP------------------------ 211
Query: 123 GKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTV---------EEILAKMEQPRK 173
+ PP P A A P APAP PAS T + + +A + +
Sbjct: 212 -PDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAE 270
Query: 174 EVLASPDRL----WGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSP 229
ASP R GS L N + + PR++ P S++ +QE P K
Sbjct: 271 ATRASPPRSPAEPKGSALGPNPEPHLTF-PRSF-KVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 230 AECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIP---SSPAPSSENGGPA 286
++ S+ P LP + AS P +P P + AP+S G
Sbjct: 329 GATKKAPSRLP----LPPSFHI-----RPASQVYPDRAPEPDCPGELKATAPASPRLG-Q 378
Query: 287 SPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDE 346
S E +G+ P +P L PP P P A P P A AA P
Sbjct: 379 SQSQADERAGTPPPAPPLPPPAPPLP----------PPAPPLPPAAPPLPCAQKAAHPPA 428
Query: 347 GSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPS 406
G TP PA P+P+ P PE ++ P P ++ +L + +
Sbjct: 429 GFTKTPKSSSPA----LKPKPNPPSPE----NTASSAPVDWRDP-SQMEKLRNELAAYLC 479
Query: 407 GGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGA 466
G E + +H RP V + EG ++E +L +LP ++ G
Sbjct: 480 GSRREDRFLSH-RPGPTVAPQSKEGKKGPRLPEKE----TLLSLPAKDTPPGVPEKSLGG 534
Query: 467 ESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPS----------PITEASEAAEAAEAGNLA 516
S + T P+ + DSP PS ++ A+E G+L
Sbjct: 535 SSLTETEAAPSLTLPS----VDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLP 590
Query: 517 VSSREEG--VSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQF---PAVPLEP 571
R EG + + G A S V + P S T QP+ PA+P
Sbjct: 591 PKPRLEGGRICENG-----ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP--- 642
Query: 572 LPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILE---PVLGQEQPAAPD 628
P P +P + + G +PL AT P+ P + P
Sbjct: 643 -PKATPEPAIPPKATLWPATPPKATLGPATPLK-ATSGPTTPLKATSGPAIASTATTLPT 700
Query: 629 QPCVLFAD---APEPGQALPVEEEAVTLARAETTQARTEAQDL 668
L A+ P P +E T ++A + +EA L
Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRL 743
Score = 43.5 bits (101), Expect = 0.002
Identities = 117/497 (23%), Positives = 166/497 (33%), Gaps = 108/497 (21%)
Query: 31 PGDTRAKPPVKPK---------------PRALPAKPALPAKPSLLVPVGPRPPRGPLAEL 75
PG+ +A P P+ P A P P P P P P PP P L
Sbjct: 363 PGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP---PAPPLPPAAP--PL 417
Query: 76 PSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPAR 135
P A+K A P G +K P +P A K +P P +P
Sbjct: 418 PCAQK----AAHPPAGFTKTPKSSSP--------------------ALKPKPNPPSPENT 453
Query: 136 CAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSS 195
++ AP +R S+ ME+ R E+ A L GSR
Sbjct: 454 ASS------APVDWRDPSQ-------------MEKLRNELAA---YLCGSR------RED 485
Query: 196 RYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDL 255
R+ G T AP+ ++G R +E + PA ++ PE+ S L +
Sbjct: 486 RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA--KDTPPGVPEKSLGGSSLT---ET 540
Query: 256 AKAASSELPADISKPWIP-SSPAPS-----SENGGPASPGLPAEAS---GSGPGSPHLH- 305
A S LP S +IP SP PS +E S EA GS P P L
Sbjct: 541 EAAPSLTLP---SVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEG 597
Query: 306 ---------------PPDKSSPCHSQLLEAQTPEASQASPCPAVTPSA-PSAALPDEGSR 349
P K+ P S L T +A PA+ P A P A+P + +
Sbjct: 598 GRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATL 657
Query: 350 HTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGE 409
+P G + +S P L+ S +T+ +L+ + P+G
Sbjct: 658 WPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQP 717
Query: 410 EEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESN 469
E+ P+ + P+Q G G L +P +S
Sbjct: 718 EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQS- 776
Query: 470 WSLSQSFEWTFPTRPSG 486
SLS+ PT G
Sbjct: 777 -SLSREVAVVMPTLARG 792
Score = 37.0 bits (84), Expect = 0.17
Identities = 133/597 (22%), Positives = 186/597 (31%), Gaps = 132/597 (22%)
Query: 13 ASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPP---- 68
A PLP + P G + P +KPKP P P + PV R P
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN-----PPSPENTASSAPVDWRDPSQME 468
Query: 69 --RGPLAEL--PSARKMNMLA-------GPQPYGGSKRP----------LPFAPRP--AV 105
R LA S R+ L+ PQ G K P LP P
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 106 EASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL 165
E S GG + ET E P LT P+ P + +P P +
Sbjct: 529 EKSLGGSSLTET-------EAAPSLTLPSVDYIP---QDSPTPSVRQIRNELEARLSSAA 578
Query: 166 AKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRT------YGTTTAPRDEDGSTLFRG 219
K +P L RL G R+ N + TT P +T +
Sbjct: 579 EKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLP-----TTSLQP 633
Query: 220 WSQEGPVKSPAECREEH--------SKTPEERSLPSDL-------------AFNGDLAKA 258
+ GP P E TP + +L A +G +
Sbjct: 634 KAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIAS 693
Query: 259 ASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHP------------ 306
++ LP S+ P+ + PAS + + G GSP
Sbjct: 694 TATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAA 753
Query: 307 -PDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPS-----AALPDEGSRHTPSPGLPAEG 360
P K+SP ++ P Q+S V P+ AA P E PGLPA
Sbjct: 754 FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPA-- 811
Query: 361 APEAPRPSSPPPEVL-EPHSLDQPPATSPRPLI-----------EVGELLDLTRTFPSGG 408
+ P + P E+L P + + SP L+ VG L R+ G
Sbjct: 812 --KPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALG--RSSLPGS 867
Query: 409 EEEAKGDAHLRPTSLVQRRFSEG---VLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFG 465
+ A S+ + + V+ ++ EK +P G +L D
Sbjct: 868 LRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRD---- 923
Query: 466 AESNWSLSQSFEWTFP--------------TRPSGLGVWRLDSPPPSPITEASEAAE 508
AE LS+ WT P P G + + S PPSP + E E
Sbjct: 924 AEGT-ELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEE 979
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 70.5 bits (171), Expect = 1e-11
Identities = 118/506 (23%), Positives = 164/506 (32%), Gaps = 124/506 (24%)
Query: 197 YGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKS--PAECREEHSKTPEERSLPSDLA---- 250
YG + T + E G+ + + P+ + P +E H S+P D A
Sbjct: 53 YGDNRFNTVS----ESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEV 108
Query: 251 ------FNGDLAKAAS--SELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSP 302
NG+L +S P + + P P GPA PG P + S GSP
Sbjct: 109 TGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPP-----GPA-PGPPQDISEPPGGSP 162
Query: 303 HLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAP-----SAALPDEGSRHTPSPGLP 357
PP + P LLE P + P P + +P S ++P P+P L
Sbjct: 163 LPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLA 222
Query: 358 AEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAH 417
P P P+ PP PH++ TR FP GG + K D
Sbjct: 223 FLAPPPPPVPAPAPPAPASPHTVG-------------------TRLFPPGGVTKWKSDVA 263
Query: 418 LRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFE 477
L R S P E G +L P E + + +SF+
Sbjct: 264 LNGRQAEATRAS-----PPRSPAEPKGSALGPNP---------------EPHLTFPRSFK 303
Query: 478 WTFPTRPSGLGVWRLDSPPPSPI-TEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPS 536
PPP+P+ T + EA EA +EEG +++ P
Sbjct: 304 ----------------VPPPTPVRTSSIPVQEAQEA-----PRKEEGATKKAPSRLPLPP 342
Query: 537 GSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPL 596
P + GE + PA P G QA+ER
Sbjct: 343 SFHIRPASQVYPDRAPEPDCPGELKATAPASP---------RLGQSQSQADER------- 386
Query: 597 AGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARA 656
AG P P A P L P PAAP PC A P G
Sbjct: 387 AGTPPPAPPLPPPA--PPLPPPAPPLPPAAPPLPCAQKAAHPPAG--------------- 429
Query: 657 ETTQARTEAQDLCRASPEPPGPESSS 682
T+ + + P PP PE+++
Sbjct: 430 -FTKTPKSSSPALKPKPNPPSPENTA 454
Score = 55.8 bits (133), Expect = 3e-07
Identities = 159/703 (22%), Positives = 234/703 (33%), Gaps = 118/703 (16%)
Query: 6 LRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGP 65
LR S++ P + ++L+ PG P +P P LP+ PS P P
Sbjct: 119 LRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP---PGGSPLPSPPSTAPPPPP 175
Query: 66 ---RPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEA 122
PP P P + L+ P P P
Sbjct: 176 LLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTP------------------------ 211
Query: 123 GKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTV---------EEILAKMEQPRK 173
+ PP P A A P APAP PAS T + + +A + +
Sbjct: 212 -PDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAE 270
Query: 174 EVLASPDRL----WGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSP 229
ASP R GS L N + + PR++ P S++ +QE P K
Sbjct: 271 ATRASPPRSPAEPKGSALGPNPEPHLTF-PRSF-KVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 230 AECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIP---SSPAPSSENGGPA 286
++ S+ P LP + AS P +P P + AP+S G
Sbjct: 329 GATKKAPSRLP----LPPSFHI-----RPASQVYPDRAPEPDCPGELKATAPASPRLG-Q 378
Query: 287 SPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDE 346
S E +G+ P +P L PP P P A P P A AA P
Sbjct: 379 SQSQADERAGTPPPAPPLPPPAPPLP----------PPAPPLPPAAPPLPCAQKAAHPPA 428
Query: 347 GSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPS 406
G TP PA P+P+ P PE ++ P P ++ +L + +
Sbjct: 429 GFTKTPKSSSPA----LKPKPNPPSPE----NTASSAPVDWRDP-SQMEKLRNELAAYLC 479
Query: 407 GGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGA 466
G E + +H RP V + EG ++E +L +LP ++ G
Sbjct: 480 GSRREDRFLSH-RPGPTVAPQSKEGKKGPRLPEKE----TLLSLPAKDTPPGVPEKSLGG 534
Query: 467 ESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPS----------PITEASEAAEAAEAGNLA 516
S + T P+ + DSP PS ++ A+E G+L
Sbjct: 535 SSLTETEAAPSLTLPS----VDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLP 590
Query: 517 VSSREEG--VSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQF---PAVPLEP 571
R EG + + G A S V + P S T QP+ PA+P
Sbjct: 591 PKPRLEGGRICENG-----ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP--- 642
Query: 572 LPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILE---PVLGQEQPAAPD 628
P P +P + + G +PL AT P+ P + P
Sbjct: 643 -PKATPEPAIPPKATLWPATPPKATLGPATPLK-ATSGPTTPLKATSGPAIASTATTLPT 700
Query: 629 QPCVLFAD---APEPGQALPVEEEAVTLARAETTQARTEAQDL 668
L A+ P P +E T ++A + +EA L
Sbjct: 701 TTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRL 743
Score = 43.5 bits (101), Expect = 0.002
Identities = 117/497 (23%), Positives = 166/497 (33%), Gaps = 108/497 (21%)
Query: 31 PGDTRAKPPVKPK---------------PRALPAKPALPAKPSLLVPVGPRPPRGPLAEL 75
PG+ +A P P+ P A P P P P P P PP P L
Sbjct: 363 PGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP---PAPPLPPAAP--PL 417
Query: 76 PSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPAR 135
P A+K A P G +K P +P A K +P P +P
Sbjct: 418 PCAQK----AAHPPAGFTKTPKSSSP--------------------ALKPKPNPPSPENT 453
Query: 136 CAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSS 195
++ AP +R S+ ME+ R E+ A L GSR
Sbjct: 454 ASS------APVDWRDPSQ-------------MEKLRNELAA---YLCGSR------RED 485
Query: 196 RYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDL 255
R+ G T AP+ ++G R +E + PA ++ PE+ S L +
Sbjct: 486 RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA--KDTPPGVPEKSLGGSSLT---ET 540
Query: 256 AKAASSELPADISKPWIP-SSPAPS-----SENGGPASPGLPAEAS---GSGPGSPHLH- 305
A S LP S +IP SP PS +E S EA GS P P L
Sbjct: 541 EAAPSLTLP---SVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEG 597
Query: 306 ---------------PPDKSSPCHSQLLEAQTPEASQASPCPAVTPSA-PSAALPDEGSR 349
P K+ P S L T +A PA+ P A P A+P + +
Sbjct: 598 GRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATL 657
Query: 350 HTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGE 409
+P G + +S P L+ S +T+ +L+ + P+G
Sbjct: 658 WPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQP 717
Query: 410 EEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESN 469
E+ P+ + P+Q G G L +P +S
Sbjct: 718 EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQS- 776
Query: 470 WSLSQSFEWTFPTRPSG 486
SLS+ PT G
Sbjct: 777 -SLSREVAVVMPTLARG 792
Score = 37.0 bits (84), Expect = 0.17
Identities = 133/597 (22%), Positives = 186/597 (31%), Gaps = 132/597 (22%)
Query: 13 ASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPP---- 68
A PLP + P G + P +KPKP P P + PV R P
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN-----PPSPENTASSAPVDWRDPSQME 468
Query: 69 --RGPLAEL--PSARKMNMLA-------GPQPYGGSKRP----------LPFAPRP--AV 105
R LA S R+ L+ PQ G K P LP P
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 106 EASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL 165
E S GG + ET E P LT P+ P + +P P +
Sbjct: 529 EKSLGGSSLTET-------EAAPSLTLPSVDYIP---QDSPTPSVRQIRNELEARLSSAA 578
Query: 166 AKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRT------YGTTTAPRDEDGSTLFRG 219
K +P L RL G R+ N + TT P +T +
Sbjct: 579 EKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLP-----TTSLQP 633
Query: 220 WSQEGPVKSPAECREEH--------SKTPEERSLPSDL-------------AFNGDLAKA 258
+ GP P E TP + +L A +G +
Sbjct: 634 KAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIAS 693
Query: 259 ASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHP------------ 306
++ LP S+ P+ + PAS + + G GSP
Sbjct: 694 TATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAA 753
Query: 307 -PDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPS-----AALPDEGSRHTPSPGLPAEG 360
P K+SP ++ P Q+S V P+ AA P E PGLPA
Sbjct: 754 FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPA-- 811
Query: 361 APEAPRPSSPPPEVL-EPHSLDQPPATSPRPLI-----------EVGELLDLTRTFPSGG 408
+ P + P E+L P + + SP L+ VG L R+ G
Sbjct: 812 --KPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALG--RSSLPGS 867
Query: 409 EEEAKGDAHLRPTSLVQRRFSEG---VLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFG 465
+ A S+ + + V+ ++ EK +P G +L D
Sbjct: 868 LRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRD---- 923
Query: 466 AESNWSLSQSFEWTFP--------------TRPSGLGVWRLDSPPPSPITEASEAAE 508
AE LS+ WT P P G + + S PPSP + E E
Sbjct: 924 AEGT-ELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEE 979
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 69.7 bits (169), Expect = 2e-11
Identities = 174/707 (24%), Positives = 233/707 (32%), Gaps = 140/707 (19%)
Query: 14 SPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPA----KPSLLVPVGPRPPR 69
SPL EE PT P +R PP P LPA P A +P P+ P P
Sbjct: 447 SPLSPPPEES--PTSPPPEASRLSPP----PEELPASPLPEALHLSRPLEESPLSPPPEE 500
Query: 70 GPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPP 129
PL+ P P PL +P E S A + P
Sbjct: 501 SPLS-------------PPPESSPFSPLEESPLSPPEESPPSPALE------------TP 535
Query: 130 LTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTF 189
L+PP A+P +P P E + E +++ P +E SP
Sbjct: 536 LSPPPE-ASPLSPPFEESPLSPPPEELPTSPPPE-ASRLSPPPEESPMSP---------- 583
Query: 190 NHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDL 249
P + P + S LF + +E P+ P E E P E S
Sbjct: 584 ---------PPEESPMSPP--PEASRLFPPF-EESPLSPPPE--ESPLSPPPEAS----- 624
Query: 250 AFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDK 309
S P D P SP P P SP P L PP +
Sbjct: 625 ---------RLSPPPED-----SPMSPPPEE---SPMSPPPEVSRLSPLPVVSRLSPPPE 667
Query: 310 SSPCHSQLLEAQT---PEASQASPCPAVTPSAPSAALPDEGSRHTPSP-----GLPAEGA 361
SP E+ T PEAS+ SP P +P++P P E S +P P LP E +
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP----PPEDSPASPPPEDSLMSLPLEES 723
Query: 362 PEAPRPSSPP--PEVLEPHSLDQP--PATSPRP----LIEVGELLDLTRTFPSGGEEEAK 413
P P P P P PH +P P SPRP L E L+
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 414 GDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLS 473
+ HL P +EG SP ++ L + P ES+ S
Sbjct: 784 EEPHLSPQ-------AEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLS-P 835
Query: 474 QSFEWTFPTRPSGLGVW-RLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAG 532
QS E RP + L+ PP SP E E G G+ +
Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPE----KPPEEPGQCPAPEELPLFPPPGEPSL 891
Query: 533 SAPSGSGSSWVQGDDP------SMSLTQKGDGESQPQFP-----AVPLEPLPTTEGTPGL 581
S G + G+ P + L+ G+ PQ PL P+ T P L
Sbjct: 892 SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951
Query: 582 -PLQQAEERY------ESQEPLAG-----QESPLPLATREAALPILEPVLGQEQPAAPDQ 629
PL + E + + + PLA SP P A P+ P++ P +P
Sbjct: 952 SPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV-PPMILPPSPGSPVG 1010
Query: 630 PCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPP 676
P P P Q P+ + ++ + +Q A L SP P
Sbjct: 1011 PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP 1057
Score = 68.2 bits (165), Expect = 7e-11
Identities = 180/766 (23%), Positives = 250/766 (32%), Gaps = 149/766 (19%)
Query: 13 ASPLPREMEE-------ELVPTGSEPGDTRAKPP-----VKPKPRALPAKPALPAK---- 56
ASPL EE E +PT P +R PP + P P P P A
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFP 601
Query: 57 PSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQE 116
P P+ P P PL+ P A +++ P P +P P V +
Sbjct: 602 PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
Query: 117 TG--KEEAGKEEPP---PLTPPARCAAPGGVRKAPAP-----FRPASERFAATTVEEILA 166
EE+ PP P +PP P R +P P P + A+ E+ L
Sbjct: 662 LSPPPEESPLSPPPEESPTSPP-----PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
Query: 167 KMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPV 226
+ +L P+ + PR+ G +PR E+ R E P
Sbjct: 717 SLPLEESPLLPLPE-------------EPQLCPRSEGPHLSPRPEEPHLSPR---PEEPH 760
Query: 227 KSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAP---SSENG 283
SP S PEE L A L P + P S +
Sbjct: 761 LSPQAEEPHLSPQPEEPCL---------CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE 811
Query: 284 GPASPGLPAEASGS-GPGSPHLHPPDKSSPCHSQLLEAQ--TPEASQ--ASPCPAVTPSA 338
P +P E S P HL P PC S E +PE + SP P P
Sbjct: 812 EPHLSPVPEEPCLSPQPEESHL-SPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE 870
Query: 339 PSAALPDEGSRHTPSPGLPA----EGAPEAPRPSSPP-------------------PEVL 375
P E P PG P+ G P P PP P+++
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 376 EPHSLDQP-----PATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSE 430
P L P A +P L +GEL +P G AKGD+ P S + E
Sbjct: 931 PPDPLPPPLSPIITAAAPPALSPLGEL-----EYPFG----AKGDSD--PESPLAAPILE 979
Query: 431 GVLQSPSQ----DQEKLGGSLAALPQGQGSQLA-----LDRPFGAESNWSLSQSF-EWTF 480
+ P + D E + + LP GS + L P + + L S
Sbjct: 980 TPISPPPEANCTDPEPVPPMI--LPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNS 1037
Query: 481 PTRPSGLGVWRLDSPPP-SPITEASEAAEAAEAGNLAVS--SREEGVSQQGQGAGSAPSG 537
P L P P SPI + ++ AE + S E + + PS
Sbjct: 1038 PPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP 1097
Query: 538 SGSSWVQGDDPSMSLTQ-KGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPL 596
G P+ +L G GE PL+ + PG +P
Sbjct: 1098 MGDLSCPAPSPAPALDDFSGLGED-----TAPLDGI----DAPG------------SQPE 1136
Query: 597 AGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPE-PGQALPVEEEAVTLAR 655
GQ +P LA+ PVL + AP P ++ + + GQ P EE+ A
Sbjct: 1137 PGQ-TPGSLASELKG----SPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAP 1191
Query: 656 AETTQARTEAQDLCRASPEPPGPESSSRW--LDDLLASPPPSGGGA 699
T D+ ++S+ + + LL SP P GGG+
Sbjct: 1192 VAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGS 1237
Score = 60.1 bits (144), Expect = 2e-08
Identities = 123/482 (25%), Positives = 172/482 (35%), Gaps = 75/482 (15%)
Query: 262 ELPADISKPWIP---SSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDK--SSPCHSQ 316
E P + P +P SP P SP P EAS P PP++ +SP
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEESPTSP--PPEASRLSP------PPEELPASPLPEA 482
Query: 317 LLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTP---SPGLPAEGAPEAP---RPSSP 370
L ++ E S SP P +P +P P E S +P SP P E +P +P P SP
Sbjct: 483 LHLSRPLEESPLSPPPEESPLSP----PPESSPFSPLEESPLSPPEESPPSPALETPLSP 538
Query: 371 PPEV------LEPHSLDQPP---ATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPT 421
PPE E L PP TSP P E L P E +
Sbjct: 539 PPEASPLSPPFEESPLSPPPEELPTSPPP--EASRLSPPPEESPMSPPPEESPMSPPPEA 596
Query: 422 SLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLA---LDRPFGAESNWS-LSQSFE 477
S + F E L P ++ P + S+L+ D P S +S E
Sbjct: 597 SRLFPPFEESPLSPPPEES-------PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE 649
Query: 478 WTFPTRPSGLGVWRLDSPPP-----SPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAG 532
+R S L V SPPP SP E S + EA L+ + S + +
Sbjct: 650 ---VSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
Query: 533 SAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQ-----QAE 587
++P S + S L + + P+ L P P P + QAE
Sbjct: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766
Query: 588 ERY---ESQEPLAGQESPLPLATREAALPILEPVLGQ-------EQP---AAPDQPCVLF 634
E + + +EP P + +A P L P + E+P P++PC+
Sbjct: 767 EPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL-- 824
Query: 635 ADAPEPGQALPVEEEAVTLARAETTQARTEAQ--DLCRASPEPPGPESSSRWLDDLLASP 692
+ PE P EE R E + E + L +PP ++L P
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP 884
Query: 693 PP 694
PP
Sbjct: 885 PP 886
Score = 55.8 bits (133), Expect = 3e-07
Identities = 110/435 (25%), Positives = 152/435 (34%), Gaps = 80/435 (18%)
Query: 273 PSSPAPSSENGGP-ASPGLPAEASGSGPGS---PHLHPPDKS--SPCHSQLLEAQTPEAS 326
P P P P G+ E P + P L PP++S SP + + PEAS
Sbjct: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEAS 465
Query: 327 QASPCPAVTPSAP-----SAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLD 381
+ SP P P++P + P E S +P P E +P +P P S P LE L
Sbjct: 466 RLSPPPEELPASPLPEALHLSRPLEESPLSPPP----EESPLSPPPESSPFSPLEESPLS 521
Query: 382 QPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQE 441
P + P P +E P EA S + F E L P ++
Sbjct: 522 PPEESPPSPALET----------PLSPPPEA---------SPLSPPFEESPLSPPPEE-- 560
Query: 442 KLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPIT 501
L P + S+L+ P ES P P + P SP
Sbjct: 561 -----LPTSPPPEASRLS---PPPEES------------PMSPPP------EESPMSPPP 594
Query: 502 EASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQ 561
EAS E L+ E +S + + +P +D MS + S
Sbjct: 595 EASRLFPPFEESPLSPPPEESPLSPPPEASRLSP--------PPEDSPMSPPPEESPMSP 646
Query: 562 PQFPAVP-LEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVL- 619
P P V L PLP P EE S P SP P A+R + P P
Sbjct: 647 P--PEVSRLSPLPVVSRLSPPP----EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP 700
Query: 620 -GQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGP 678
++ PA+P L + E LP+ EE R+E ++ SP P P
Sbjct: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE-PHLSPRPEEP 759
Query: 679 ESSSRWLDDLLASPP 693
S + + L+ P
Sbjct: 760 HLSPQAEEPHLSPQP 774
Score = 52.0 bits (123), Expect = 5e-06
Identities = 180/812 (22%), Positives = 257/812 (31%), Gaps = 169/812 (20%)
Query: 26 PTGSEPGDTRAKPPVKPKPRALPA----KPALPAKPSLLVPVGPRPPRGPLAELPSARKM 81
P +PG+ PP P+ + KP P+ +L VP P G +E
Sbjct: 2218 PGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASE------- 2270
Query: 82 NMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEP---PP----LTPPA 134
L P P+G S++ L E KEE G P PP + P+
Sbjct: 2271 -PLLSPPPFGESRKAL------------------EVKKEELGASSPSYGPPNLGFVDSPS 2311
Query: 135 RCAAPGGVR-KAP----APFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTF 189
GG+ K P AP P + + + L E P + LA
Sbjct: 2312 SGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALA------------ 2359
Query: 190 NHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEE------R 243
P +FR S P P PE R
Sbjct: 2360 ------------------PSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPR 2401
Query: 244 SLPSDL-----AFNGDLAKAASSELPADIS-KPWIPSSPAPSSENGGPASPGLPAEASGS 297
SLPSD A + + S P +S + + PS P ++ P S P+
Sbjct: 2402 SLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP-PSRPQSR 2460
Query: 298 GPGSPHLHPPDKSSP----------CHSQLLEAQTPEASQASPCPAVTPSAPSAALPD-- 345
P +P LH P + P H+ L P A A P + PS P+
Sbjct: 2461 DPFAP-LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFV 2519
Query: 346 -----EGSRHTPSP---------GLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRP- 390
TPSP G P+ P P+P PPP + H P P+
Sbjct: 2520 RSPGTGAFVGTPSPMRFTFPQAVGEPSL-KPPVPQPGLPPPHGINSHFGPGPTLGKPQST 2578
Query: 391 --LIEVGELLDLTRTF--PSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGS 446
+ G SG E+ G + LRP S VL P+ D GS
Sbjct: 2579 NYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPS---------VLPPPAPD-----GS 2624
Query: 447 LAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPI--TEAS 504
L L G + + P + P P S + TE
Sbjct: 2625 LPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG------TQDPGMSGLSQTELE 2678
Query: 505 EAAEAAEAGNLAVSS--REEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQP 562
+ + L + + + Q+ + A +A G G +PS ++ S+
Sbjct: 2679 KQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQ---LSRG 2735
Query: 563 QFPAVPLEPLPTTEGTPGLPLQ---QAEERYESQEPLAGQESPLPLATREAALPILEPVL 619
Q P + + G P L + S + L+ P P AT + ++
Sbjct: 2736 QTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLS---RPPPPATPSSMDVNSRQLV 2792
Query: 620 GQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRAS-PEPPGP 678
G Q + AP PG +LP++++ L + + A T + A P PGP
Sbjct: 2793 GGSQ--------AFYQRAPYPG-SLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGP 2843
Query: 679 ESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDL---QSEFGIT 735
E + L SP G G + P+ E L QK L + F
Sbjct: 2844 ELGRQ----ALGSPLAGISTRLPGPGEPVPGPAGPAQFIE-LRHNVQKGLGPGGTPFPGQ 2898
Query: 736 GDPQPSSFSPSSWCQGASQDYGLGGASPRGDP 767
G PQ F P S GL G + G P
Sbjct: 2899 GPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLP 2930
Score = 38.9 bits (89), Expect = 0.044
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 319 EAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPG-LPAEGAPEA--PRPSSPPPE 373
E +P S +P PA P+ P LP E P P LP +PE+ P+P + PPE
Sbjct: 4912 EEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969
Score = 37.4 bits (85), Expect = 0.13
Identities = 47/158 (29%), Positives = 61/158 (38%), Gaps = 37/158 (23%)
Query: 224 GPVKSPAECREEHSKTPEE--RSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSE 281
G V P E K P + +PS F LA A E + P P P+P+
Sbjct: 2148 GSVPGPDSPGELFLKLPPQVPAQVPSQDPFG--LAPAYPLEPRFPTAPPTYPPYPSPT-- 2203
Query: 282 NGGPASPGLPAEASGSGPGSP---HLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSA 338
G PA P + +S G G P H PP TP ++P P + P
Sbjct: 2204 -GAPAQPPMLGASSRPGAGQPGEFHTTPPG-------------TPRHQPSTPDPFLKPRC 2249
Query: 339 PS---AALPDEGSRHTPSPGLPAEGAPEAPRP-SSPPP 372
PS A+P+ SPG+ G +A P SPPP
Sbjct: 2250 PSLDNLAVPE-------SPGV---GGGKASEPLLSPPP 2277
Score = 33.1 bits (74), Expect = 2.4
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 14/107 (13%)
Query: 1386 PGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGM-----ETGEALSFGASP 1440
PGL + + G G T G + Q +Y+ ++ HP+ + TGE S+G SP
Sbjct: 2554 PGLPPPHGINSH-FGPGPTLG-KPQSTNYTVATGNFHPSGSPLGPSSGSTGE--SYGLSP 2609
Query: 1441 GRCPARPPPSGSQGLLEEMLAASSSKA-----VARRESAASGLGGLL 1482
R P+ PP G L + +S ++ V +RE +G+G L
Sbjct: 2610 LRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSL 2656
Score = 32.7 bits (73), Expect = 3.1
Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 23/102 (22%)
Query: 274 SSPAPSSENGGPASPGLPAEASGSGPGSPHLHP-PDKSSPCHSQLLEAQTPEASQASPCP 332
+ P P PA PG A +GP +HP P SSP Q P+ P
Sbjct: 4279 AGPRPQGPPRLPAPPG----ALSTGPVLGPVHPTPPPSSP--------QEPKR------P 4320
Query: 333 AVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEV 374
+ PS PS+ LP E PG P P+ P PP V
Sbjct: 4321 SQLPS-PSSQLPTEAQLPPTHPGTP---KPQGPTLEPPPGRV 4358
Score = 32.0 bits (71), Expect = 5.4
Identities = 30/96 (31%), Positives = 35/96 (36%), Gaps = 31/96 (32%)
Query: 301 SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEG 360
SP PP + HS + Q S P PS P +
Sbjct: 4883 SPAPEPPTQ----HSYTYNVSNLDVRQLSAPPPEEPSPPPS------------------- 4919
Query: 361 APEAPRPSSPPPEVL-----EPHSLDQPPATSPRPL 391
P AP P+SPP E L EP L +PP SP PL
Sbjct: 4920 -PLAPSPASPPTEPLVELPTEP--LAEPPVPSPLPL 4952
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 66.6 bits (161), Expect = 2e-10
Identities = 125/520 (24%), Positives = 171/520 (32%), Gaps = 91/520 (17%)
Query: 283 GGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVT---PSAP 339
G SP L A +G GP P PP +S S ++ SQ P P + PS P
Sbjct: 587 GSELSPELQAAMAGGGP-EPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPP 645
Query: 340 SAALPDEGSRHTPS-----PG--------LPAEGAPEAPRPSSPPPEVLEPHSLDQPPAT 386
EG+ P PG + +G+P +P P PP L PPAT
Sbjct: 646 QERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPAT 705
Query: 387 SPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPT----SLVQRRFSEGVL--QSPSQDQ 440
P P L+R P+ G+ E + + + T + + RR L SPS
Sbjct: 706 PPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTP 765
Query: 441 EKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPI 500
G+ P+ Q L R + P P L SP P P+
Sbjct: 766 TPARGT----PRSQSFALRARR--------------KGPPPPPPKRLSSVSGPSPEPPPL 807
Query: 501 TEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGES 560
E+ E A S G S+ AP+G S + ++P T G S
Sbjct: 808 DESPGPKEGATGPRRRTLSEPAGPSE--PPGPPAPAGPASD-TEEEEPGPEGTPPSRGSS 864
Query: 561 QPQFPAV------------PLEPLP-TTEGTPGLPLQQAEERYESQEPLAGQESPLPL-- 605
P P P P T PGL E + P + PL
Sbjct: 865 GEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTAL 924
Query: 606 -------ATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAET 658
AT A P+ P G+ PA+ PEP +LP + LA +
Sbjct: 925 LAFGVASATPGPAAPLPSPTPGESPPASS-------LPQPEP-SSLPAQGVPTPLAPSPA 976
Query: 659 TQARTEAQDLCRASPEPPGP----ESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPS 714
Q P PGP ++SRW + PP + + GA
Sbjct: 977 MQPPV---------PPCPGPGLESSAASRWNGE--TEPPAAPAALLKVPGAGTAPKPVSV 1025
Query: 715 TCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQ 754
C++ L +S L G P P S + G +Q
Sbjct: 1026 ACTQ--LAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQ 1063
Score = 44.3 bits (103), Expect = 0.001
Identities = 89/381 (23%), Positives = 129/381 (33%), Gaps = 78/381 (20%)
Query: 7 RESSAMASPLPREMEEELV---PTGSEPGD-------------TRAKPPVKPKP-RALPA 49
R S +++ P P E + E P GS G R P V P P R P
Sbjct: 714 RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPR 773
Query: 50 KPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEAST 109
+ + P P P R ++ ++GP P PL +P P E +T
Sbjct: 774 SQSFALRARRKGPPPPPPKR-----------LSSVSGPSP---EPPPLDESPGPK-EGAT 818
Query: 110 GGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKME 169
G + T E AG EPP PAP PAS+ + E
Sbjct: 819 GPR--RRTLSEPAGPSEPPG---------------PPAPAGPASD-----------TEEE 850
Query: 170 QPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGST-LFRGWSQEGPVKS 228
+P E G L F +G+ R PR+ L ++ VK
Sbjct: 851 EPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKR 910
Query: 229 PAECREEH------------SKTPEERS-LPSDLAFNGDLAKAASSELPADISKPWIPS- 274
+CRE S TP + LPS A + P+ + +P+
Sbjct: 911 RPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTP 970
Query: 275 -SPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPA 333
+P+P+ + P PG E+S + + PP + ++ A T + C
Sbjct: 971 LAPSPAMQPPVPPCPGPGLESSAASRWNGETEPP-AAPAALLKVPGAGTAPKPVSVACTQ 1029
Query: 334 VTPSAPSAALPDEGSRHTPSP 354
+ S P A P G R P P
Sbjct: 1030 LAFSGPKLA-PRLGPRPVPPP 1049
Score = 42.4 bits (98), Expect = 0.004
Identities = 94/402 (23%), Positives = 124/402 (30%), Gaps = 85/402 (21%)
Query: 64 GPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAG 123
GP P P A PS + A + G S+ +PA + S G + + G
Sbjct: 602 GPEPLPLPPARSPSQESIG--ARSRGSGHSQE------QPAPQPSGGDPSPPQERNLPEG 653
Query: 124 KEEPPPLT--------PPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQP---- 171
E PP L PP P G +PAP P +A + + A P
Sbjct: 654 TERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPK 713
Query: 172 -RKEVLASPDRLWG-----------------SRLTFNHDGSS--RYGPRTYGTTTAPRDE 211
R L+ P G + LT S+ R P T
Sbjct: 714 RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPR 773
Query: 212 DGSTLFRGWSQEGPVKSPAECREEHSKTPEERSL-----PSDLAFNGDLAKAASSELPAD 266
S R + P P +PE L P + A + P++
Sbjct: 774 SQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSE 833
Query: 267 ISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLH--------------PPDKSSP 312
P P+ PA +E P G P SG G P PP + +P
Sbjct: 834 PPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETP 893
Query: 313 ----CHSQLLEAQT----PEASQASPCP--------AVTPSAPSAALPDEGSRHTPSPGL 356
L E+ T P+ + P A P+A LP TP
Sbjct: 894 VPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSP----TPGESP 949
Query: 357 PAEGAPEAPRPSSPP----PEVLEPHSLDQPPA-TSPRPLIE 393
PA P+ P PSS P P L P QPP P P +E
Sbjct: 950 PASSLPQ-PEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE 990
Score = 41.2 bits (95), Expect = 0.009
Identities = 88/354 (24%), Positives = 122/354 (34%), Gaps = 63/354 (17%)
Query: 1374 PEPGLRHNGSLSPGLEARDPLEARELGVGETSG--------PETQGEDYSSSSLEPHPAD 1425
P P R + PG D E VG T G P +S S+ P PA
Sbjct: 710 PRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA- 768
Query: 1426 PGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEE 1485
T + SF R PPP ++ S + ES +E
Sbjct: 769 --RGTPRSQSFALRARRKGPPPPPPKRLS----SVSGPSPEPPPLDESPGP-------KE 815
Query: 1486 GAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVD-GTWGSSAAR--------WSDQG 1536
GA G + + EP S P P P G AS TE+ + G G+ +R ++++G
Sbjct: 816 GA-TGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEG 874
Query: 1537 PAQTSRRPS-QGPPARS----PSQDFSFIEDTEILDSAMYRSRANLGRKRGHRAPVIRPG 1591
+RP GPP R P DF+ E D+ R + R P+
Sbjct: 875 NLTIKQRPKPAGPPPRETPVPPGLDFNLTES----DTVKRRPKCR------EREPLQTAL 924
Query: 1592 GTLGLSEAADSDAHLFQDSTEPRASRVPSSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGL 1651
G++ A A P S P PQ + SL +G+ L P
Sbjct: 925 LAFGVASATPGPA-------APLPSPTPGESPPASSLPQPEPS--SLPAQGVPTPLAP-- 973
Query: 1652 SPSALKAKLRPRNRSAEEGELAESKSSQKESAVQRSKSCKVPGLGKPLTLPPKP 1705
SP A++ + P E A + + E + KVPG G PKP
Sbjct: 974 SP-AMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAG----TAPKP 1022
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 66.6 bits (161), Expect = 2e-10
Identities = 125/520 (24%), Positives = 171/520 (32%), Gaps = 91/520 (17%)
Query: 283 GGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVT---PSAP 339
G SP L A +G GP P PP +S S ++ SQ P P + PS P
Sbjct: 669 GSELSPELQAAMAGGGP-EPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPP 727
Query: 340 SAALPDEGSRHTPS-----PG--------LPAEGAPEAPRPSSPPPEVLEPHSLDQPPAT 386
EG+ P PG + +G+P +P P PP L PPAT
Sbjct: 728 QERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPAT 787
Query: 387 SPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPT----SLVQRRFSEGVL--QSPSQDQ 440
P P L+R P+ G+ E + + + T + + RR L SPS
Sbjct: 788 PPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTP 847
Query: 441 EKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPI 500
G+ P+ Q L R + P P L SP P P+
Sbjct: 848 TPARGT----PRSQSFALRARR--------------KGPPPPPPKRLSSVSGPSPEPPPL 889
Query: 501 TEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGES 560
E+ E A S G S+ AP+G S + ++P T G S
Sbjct: 890 DESPGPKEGATGPRRRTLSEPAGPSE--PPGPPAPAGPASD-TEEEEPGPEGTPPSRGSS 946
Query: 561 QPQFPAV------------PLEPLP-TTEGTPGLPLQQAEERYESQEPLAGQESPLPL-- 605
P P P P T PGL E + P + PL
Sbjct: 947 GEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTAL 1006
Query: 606 -------ATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAET 658
AT A P+ P G+ PA+ PEP +LP + LA +
Sbjct: 1007 LAFGVASATPGPAAPLPSPTPGESPPASS-------LPQPEP-SSLPAQGVPTPLAPSPA 1058
Query: 659 TQARTEAQDLCRASPEPPGP----ESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPS 714
Q P PGP ++SRW + PP + + GA
Sbjct: 1059 MQPPV---------PPCPGPGLESSAASRWNGE--TEPPAAPAALLKVPGAGTAPKPVSV 1107
Query: 715 TCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQ 754
C++ L +S L G P P S + G +Q
Sbjct: 1108 ACTQ--LAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQ 1145
Score = 44.3 bits (103), Expect = 0.001
Identities = 89/381 (23%), Positives = 129/381 (33%), Gaps = 78/381 (20%)
Query: 7 RESSAMASPLPREMEEELV---PTGSEPGD-------------TRAKPPVKPKP-RALPA 49
R S +++ P P E + E P GS G R P V P P R P
Sbjct: 796 RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPR 855
Query: 50 KPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEAST 109
+ + P P P R ++ ++GP P PL +P P E +T
Sbjct: 856 SQSFALRARRKGPPPPPPKR-----------LSSVSGPSP---EPPPLDESPGPK-EGAT 900
Query: 110 GGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKME 169
G + T E AG EPP PAP PAS+ + E
Sbjct: 901 GPR--RRTLSEPAGPSEPPG---------------PPAPAGPASD-----------TEEE 932
Query: 170 QPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGST-LFRGWSQEGPVKS 228
+P E G L F +G+ R PR+ L ++ VK
Sbjct: 933 EPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKR 992
Query: 229 PAECREEH------------SKTPEERS-LPSDLAFNGDLAKAASSELPADISKPWIPS- 274
+CRE S TP + LPS A + P+ + +P+
Sbjct: 993 RPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTP 1052
Query: 275 -SPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPA 333
+P+P+ + P PG E+S + + PP + ++ A T + C
Sbjct: 1053 LAPSPAMQPPVPPCPGPGLESSAASRWNGETEPP-AAPAALLKVPGAGTAPKPVSVACTQ 1111
Query: 334 VTPSAPSAALPDEGSRHTPSP 354
+ S P A P G R P P
Sbjct: 1112 LAFSGPKLA-PRLGPRPVPPP 1131
Score = 42.4 bits (98), Expect = 0.004
Identities = 94/402 (23%), Positives = 124/402 (30%), Gaps = 85/402 (21%)
Query: 64 GPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAG 123
GP P P A PS + A + G S+ +PA + S G + + G
Sbjct: 684 GPEPLPLPPARSPSQESIG--ARSRGSGHSQE------QPAPQPSGGDPSPPQERNLPEG 735
Query: 124 KEEPPPLT--------PPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQP---- 171
E PP L PP P G +PAP P +A + + A P
Sbjct: 736 TERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPK 795
Query: 172 -RKEVLASPDRLWG-----------------SRLTFNHDGSS--RYGPRTYGTTTAPRDE 211
R L+ P G + LT S+ R P T
Sbjct: 796 RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPR 855
Query: 212 DGSTLFRGWSQEGPVKSPAECREEHSKTPEERSL-----PSDLAFNGDLAKAASSELPAD 266
S R + P P +PE L P + A + P++
Sbjct: 856 SQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSE 915
Query: 267 ISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLH--------------PPDKSSP 312
P P+ PA +E P G P SG G P PP + +P
Sbjct: 916 PPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETP 975
Query: 313 ----CHSQLLEAQT----PEASQASPCP--------AVTPSAPSAALPDEGSRHTPSPGL 356
L E+ T P+ + P A P+A LP TP
Sbjct: 976 VPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSP----TPGESP 1031
Query: 357 PAEGAPEAPRPSSPP----PEVLEPHSLDQPPA-TSPRPLIE 393
PA P+ P PSS P P L P QPP P P +E
Sbjct: 1032 PASSLPQ-PEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE 1072
Score = 41.2 bits (95), Expect = 0.009
Identities = 88/354 (24%), Positives = 122/354 (34%), Gaps = 63/354 (17%)
Query: 1374 PEPGLRHNGSLSPGLEARDPLEARELGVGETSG--------PETQGEDYSSSSLEPHPAD 1425
P P R + PG D E VG T G P +S S+ P PA
Sbjct: 792 PRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA- 850
Query: 1426 PGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEE 1485
T + SF R PPP ++ S + ES +E
Sbjct: 851 --RGTPRSQSFALRARRKGPPPPPPKRLS----SVSGPSPEPPPLDESPGP-------KE 897
Query: 1486 GAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVD-GTWGSSAAR--------WSDQG 1536
GA G + + EP S P P P G AS TE+ + G G+ +R ++++G
Sbjct: 898 GA-TGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEG 956
Query: 1537 PAQTSRRPS-QGPPARS----PSQDFSFIEDTEILDSAMYRSRANLGRKRGHRAPVIRPG 1591
+RP GPP R P DF+ E D+ R + R P+
Sbjct: 957 NLTIKQRPKPAGPPPRETPVPPGLDFNLTES----DTVKRRPKCR------EREPLQTAL 1006
Query: 1592 GTLGLSEAADSDAHLFQDSTEPRASRVPSSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGL 1651
G++ A A P S P PQ + SL +G+ L P
Sbjct: 1007 LAFGVASATPGPA-------APLPSPTPGESPPASSLPQPEPS--SLPAQGVPTPLAP-- 1055
Query: 1652 SPSALKAKLRPRNRSAEEGELAESKSSQKESAVQRSKSCKVPGLGKPLTLPPKP 1705
SP A++ + P E A + + E + KVPG G PKP
Sbjct: 1056 SP-AMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAG----TAPKP 1104
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 65.5 bits (158), Expect = 4e-10
Identities = 132/558 (23%), Positives = 186/558 (33%), Gaps = 106/558 (18%)
Query: 127 PPPLTPPARCAAPGGVRKAPAPFR-PASERFAATTVEEILAKMEQPRKEVLASPDRLWGS 185
PP L PP AA A + P + + T++ + ++ +P E + R
Sbjct: 4 PPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVR---- 59
Query: 186 RLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSL 245
R+GP T S +G + R + +
Sbjct: 60 ---------RRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPA 110
Query: 246 PSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLH 305
P A AA++ P P P PAP + PA A A+ + P SP
Sbjct: 111 PPRAPRGAPAAAAAAAPPPT----PAPPPPPAPVAA-AAPARAPRAAAAAATAPPSPGPA 165
Query: 306 PPDKSSPCHSQLLEAQTPEASQASP--CPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPE 363
P P A +A+P P P+AP A P G R P PA A E
Sbjct: 166 QPG--------------PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPP---PAVAARE 208
Query: 364 APRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSL 423
P P PPP+ P QPP P+P P GG A G A RP SL
Sbjct: 209 PPLP--PPPQPPAPPQQQQPPPPQPQPP-------------PEGGAVRAGGAA--RPVSL 251
Query: 424 VQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFG-AESNWSLSQSFEWTFPT 482
+ LGGS G G +L R G E + E T
Sbjct: 252 -------------REVVRYLGGS-----GGAGGRLTRGRVQGLLEEEAAARGRLE---RT 290
Query: 483 RPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSW 542
R L + R D P +P ++ + + G V +EE GS
Sbjct: 291 RLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEV 350
Query: 543 VQGDDPSMSLTQKGDGESQPQ---------FPAVPLEPLPTTEG-TPGLPLQQA------ 586
+ D P+ + + +GE PQ P P + G PG +Q
Sbjct: 351 PESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAM 410
Query: 587 --EERYESQEPLAGQESPLPLATREAALPILE------PVLGQEQPAAPDQPCVL----- 633
E S SP+PL + ALP + P +E+P+ P + V+
Sbjct: 411 NKEGGTASVATGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSDPVEWTVMDVVEY 470
Query: 634 FADAPEPGQALPVEEEAV 651
F +A P QA +E+ +
Sbjct: 471 FTEAGFPEQATAFQEQEI 488
Score = 41.2 bits (95), Expect = 0.009
Identities = 41/132 (31%), Positives = 47/132 (35%), Gaps = 30/132 (22%)
Query: 30 EPGDTRAKPPVKPK-PRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQ 88
+P A PP P+ PR PA A A P P PP P+A AR
Sbjct: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPT---PAPPPPPAPVAAAAPAR--------- 147
Query: 89 PYGGSKRPLPFAPRPAVEASTG----GEATQETGKEEAGKEEPPPLTP--PARCAAPGGV 142
APR A A+T G A + A PP P P A P G
Sbjct: 148 -----------APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP 196
Query: 143 RKAPAPFRPASE 154
R+AP P A E
Sbjct: 197 RRAPPPAVAARE 208
Score = 40.4 bits (93), Expect = 0.015
Identities = 40/127 (31%), Positives = 47/127 (37%), Gaps = 16/127 (12%)
Query: 26 PTGSEPGDTRAKPPVKPKPRALPA--KPALPAK-PSLLVPVGPRPPR-GPLAELPSARKM 81
P G+ A PP P P PA A PA+ P PP GP P A++
Sbjct: 115 PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRA 174
Query: 82 NMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGG 141
LA P P P AP PAV G A PPL PP + AP
Sbjct: 175 APLAAPP-------PAPAAP-PAVAPPAG----PRRAPPPAVAAREPPLPPPPQPPAPPQ 222
Query: 142 VRKAPAP 148
++ P P
Sbjct: 223 QQQPPPP 229
Score = 37.0 bits (84), Expect = 0.17
Identities = 33/117 (28%), Positives = 43/117 (36%), Gaps = 28/117 (23%)
Query: 39 PVKPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLP 98
P +P PRA A P P+ P PP GP P A +A +P PLP
Sbjct: 164 PAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPA-----VAAREP------PLP 212
Query: 99 FAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASER 155
P+P +++PPP P + GG +A RP S R
Sbjct: 213 PPPQPPAPPQ---------------QQQPPP--PQPQPPPEGGAVRAGGAARPVSLR 252
Score = 35.0 bits (79), Expect = 0.63
Identities = 40/144 (27%), Positives = 44/144 (30%), Gaps = 25/144 (17%)
Query: 562 PQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQ 621
P PA P P P P +A + P G P P A R A L P
Sbjct: 128 PPTPAPPPPPAPVAAAAPARA-PRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPA--- 183
Query: 622 EQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESS 681
PAAP P V P V L A + Q P PP P+
Sbjct: 184 --PAAP--PAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQ-----PPPPQPQ-- 232
Query: 682 SRWLDDLLASPPPSGGGARRGAGA 705
PPP GG R G A
Sbjct: 233 ----------PPPEGGAVRAGGAA 246
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 65.1 bits (157), Expect = 6e-10
Identities = 91/403 (22%), Positives = 141/403 (34%), Gaps = 38/403 (9%)
Query: 29 SEPGDTRAKP-PVKPKPRALPAKPALPAKPSLLVPVGPR-PPRGPLAELPSARKMNMLAG 86
S PG ++ P PV + +A A+PA P +PS P P P AELP A ++
Sbjct: 2368 STPGSKKSPPEPVDKRAKAPKARPA-PPQPSPAPPAFTSCPAPEPFAELP-APATSLAPA 2425
Query: 87 PQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAP 146
P + RP P R A E+ G E K + +T P A +
Sbjct: 2426 PLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLRE 2485
Query: 147 APFRPASERFAATTVEEILAKMEQPRKEVLASPDRLW------------GSRLTFNHDGS 194
P + + +L+ P + P W G LTF G+
Sbjct: 2486 DPGAGGWQE-----PKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGN 2540
Query: 195 SRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGD 254
+ + + + S+ S S + E + +++ G
Sbjct: 2541 PKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
Query: 255 LAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCH 314
AASS + S SS + SS + +S + +S S S SS
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660
Query: 315 SQLLEAQTPEAS-----------QASPCPAVTPSAPSAALPDEGSRHT----PSPGLPAE 359
S + + ++ +A+P P PSA AALP + ++ PS P +
Sbjct: 2661 SSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSA-QAALPTKATKQAGKARPSAHSPGK 2719
Query: 360 GAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTR 402
P AP+P +PPP+ +P RP G L T+
Sbjct: 2720 KTP-APQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTK 2761
Score = 46.2 bits (108), Expect = 3e-04
Identities = 81/358 (22%), Positives = 123/358 (34%), Gaps = 45/358 (12%)
Query: 490 WRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPS 549
+++ PSP A + +S++ G + G AGS G+ + +G
Sbjct: 2284 YKIQCAEPSPALLVPSAKRRSRK-----TSKDTGEGKDGGTAGSEEPGAKA---RGRGRK 2335
Query: 550 MSLTQKGD-------GESQPQFPAVPLEPLPT-TEGTPGLPLQQAEERYESQEPLAGQES 601
S KGD G + P+ PL P+ T G+ P + ++R ++ +
Sbjct: 2336 PSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQ 2395
Query: 602 PLPLATREAALPILEPVLGQEQPAAPDQPCVLF---ADAPEPGQALPVEEEAVTLARAET 658
P P + P EP PA P L A P+P +A EE R
Sbjct: 2396 PSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPR--- 2452
Query: 659 TQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPST-CS 717
+ EA+ L + E S + + LL P GG + + P+ S
Sbjct: 2453 -RPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSS 2511
Query: 718 EGLLGWSQK---DLQSE------FGITGDPQP------------SSFSPSSWCQGASQDY 756
E W + DL E F +G+P+ S S SS G+S
Sbjct: 2512 EPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSS 2571
Query: 757 GLGGASPRGDPGLGERDWTSKYGQGAGEGSTREWASRCGIGQEEMEASSSQDQSKVSA 814
+S G E D G G G + +SR +SSS S S+
Sbjct: 2572 SSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSS 2629
Score = 42.7 bits (99), Expect = 0.003
Identities = 114/499 (22%), Positives = 158/499 (31%), Gaps = 120/499 (24%)
Query: 208 PRDEDGST--LFRGWSQEGPVKSPAECREEHSKTPEERSL-----PSDLAFNGDLAKAAS 260
P DE ST S G KSP E ++ +K P+ R P+ AF A
Sbjct: 2353 PTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPF 2412
Query: 261 SELPADISK----PWI--------PSSPAPSSENG--GPASPGLPAE----ASGSGPGSP 302
+ELPA + P I P + E+G GP PG AE G SP
Sbjct: 2413 AELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSP 2472
Query: 303 HLHPPDKSSPCHSQLLEAQTPEA----------SQASPCPAVTPSAPSAALP---DEGSR 349
KS LL + P A S S PA S P A P D
Sbjct: 2473 ------KSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLA 2526
Query: 350 HTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGE 409
P PGL E ++ P SP D + G E
Sbjct: 2527 QEPGPGLTFE---DSGNPKSP----------------------------DKAQAEQDGAE 2555
Query: 410 EEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESN 469
E + +S S ++ +++ G G+ A R S+
Sbjct: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
Query: 470 WSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQ 529
S S S S S + +S ++ ++ + + + SS S
Sbjct: 2616 SSSSSS-----------------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
Query: 530 GAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVP--LEPLPTTEGTPGLPLQQAE 587
+ S+ S S SS +D S S D E+ P A P LPT Q +
Sbjct: 2659 SSSSSSSSSSSSSTTDEDSSCS----SDDEAAPAPTAGPSAQAALPTK-----ATKQAGK 2709
Query: 588 ERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEP----GQA 643
R + P G+++P P +P QP P QP P G
Sbjct: 2710 ARPSAHSP--GKKTPAP-----------QPQAPPPQPTQPLQPKAQAGAKSRPKKREGVH 2756
Query: 644 LPVEEEAVTLARAETTQAR 662
LP +E R + + R
Sbjct: 2757 LPTTKELAKRQRLPSVENR 2775
Score = 41.2 bits (95), Expect = 0.009
Identities = 105/467 (22%), Positives = 158/467 (33%), Gaps = 79/467 (16%)
Query: 245 LPSDLAFNGDL-------------AKAASSELPADISKPWIPSSPAPSSENGGP-----A 286
LPSDL+F A S LP+ + ++ + +G P
Sbjct: 88 LPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLG 147
Query: 287 SPGLPAEASGSGPGSPHLHPPDKSSP--CHSQLLEAQTPEASQASPCPAVTPSAPSAALP 344
P + G GPG + P +P HS A+TP +S PA S+
Sbjct: 148 QPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAK 207
Query: 345 DEGSRHTPSPGLPAEGAPEA-PRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRT 403
+ R P L + P A +S P V++ + R + E R
Sbjct: 208 ERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAE-----RL 262
Query: 404 FPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEK-LGGSLAALPQGQGSQLALDR 462
P E + K +A L+P+ L G + P+ E GG+ A Q +G++L
Sbjct: 263 SPFLAESKTK-NAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLL--- 318
Query: 463 PFGAESNWSLSQSFEWTFP---TRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSS 519
+ E P PS L PPP+P + A AA +
Sbjct: 319 -----------RRTETLLPGPRPCPSPL------PPPPAP-PKGPPAPPAATPAGVYTVF 360
Query: 520 REEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTP 579
RE+G + P S ++ + P +Q D ++ + P L G+P
Sbjct: 361 REQGREHRVVAPTFVP--SVEAFDERPGPIQIASQARDARAREREAGRP-GVLQAPPGSP 417
Query: 580 GLPLQQAEERYESQEPLAGQESPLPL------ATREAALP-ILEPVLGQEQPAAPDQPCV 632
PL + E E + + P P ATR + P P +P A +PC
Sbjct: 418 -RPLDRPEGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPC- 475
Query: 633 LFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPE 679
+ G A P ++A L E P P GPE
Sbjct: 476 ---ERAPRGPAGPAAQQAAKLFGLEP------------GRPPPTGPE 507
Score = 34.7 bits (78), Expect = 0.83
Identities = 44/215 (20%), Positives = 73/215 (33%), Gaps = 29/215 (13%)
Query: 1368 GGVSQCPEPGLRHNGSLSPGLEARDPLEARELGVGET-------------------SGPE 1408
G ++Q P PGL S +P ++ D +A + G E+ SG E
Sbjct: 2523 GDLAQEPGPGLTFEDSGNP--KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSE 2580
Query: 1409 TQGEDYSSSSLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLAASSSKAV 1468
T+GE+ + + G A S ASP + S S ++SSS +
Sbjct: 2581 TEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 1469 ARRESAASGLGGLLEEEGAGAGAAQ--------EEVLEPGRDSPPSWRPQPDGEASQTED 1520
+ S++S + + ++ +E D + P A
Sbjct: 2641 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP 2700
Query: 1521 VDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQ 1555
T + AR S P + + P P P+Q
Sbjct: 2701 TKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQ 2735
Score = 34.3 bits (77), Expect = 1.1
Identities = 37/139 (26%), Positives = 52/139 (37%), Gaps = 31/139 (22%)
Query: 699 ARRGAGAELKDTQSPSTCS----EGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQ 754
ARRG G K T +PS S G G S L S+ +T D
Sbjct: 1522 ARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGKLSSKSLLTSD----------------- 1564
Query: 755 DYGLGGASPRGDPGLGERDWTSKYGQGAGEGSTREW---------ASRCGIGQEEMEASS 805
DY LG + G E + + G G G + W S+ I +++M +
Sbjct: 1565 DYELGAGIRKRHKG-SEEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIKKKKMASDQ 1623
Query: 806 SQDQSKVSAPGVLTAQDRV 824
Q SK+ LT QD++
Sbjct: 1624 EQLASKLDKALSLTKQDKL 1642
Score = 33.9 bits (76), Expect = 1.4
Identities = 97/432 (22%), Positives = 146/432 (33%), Gaps = 61/432 (14%)
Query: 288 PGLPAEASG------SGPGSPHLHPPDKSSPCHSQLLE----------AQTPEASQASPC 331
PGL A +G S P SP P Q LE TP + SP
Sbjct: 976 PGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPP 1035
Query: 332 PAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRP-----SSPPP----EVLEPHSLDQ 382
PA P P +E + E EAP P S PP + L PH
Sbjct: 1036 PASPPPTPGITRKEEAPENVVEK-KDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRP 1094
Query: 383 PPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQD--- 439
P + L P+ G E +P L + +E + + P ++
Sbjct: 1095 YPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLA 1154
Query: 440 QEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSP 499
+ ++ + + +G L+ P L + P+ G G L++ S
Sbjct: 1155 EREVKAEVEDMDEGPTELPPLESPL------PLPAAEAMATPSPAGGCGGGLLEAQALS- 1207
Query: 500 ITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGE 559
AE +E + V E V G+ + P + D + LT + E
Sbjct: 1208 -ATGQSCAEPSECPDF-VEGPEPRVDSPGR---TEPCTAAL------DLGVQLTPETLVE 1256
Query: 560 SQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVL 619
++ + VP+ +P E P L Q ESQ L + +P E P LEP
Sbjct: 1257 AKEEPVEVPV-AVPVVEAVPEEGLAQVAPS-ESQPTLEMSDCDVPAG--EGQCPSLEP-- 1310
Query: 620 GQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPE 679
Q A P F + Q LP E+ + A A +L +A P P
Sbjct: 1311 ---QEAVPVLGSTCFLEEASSDQFLPSLEDPLA-----GMNALAAAAELPQARPLPSPGA 1362
Query: 680 SSSRWLDDLLAS 691
+ ++ L+ L A+
Sbjct: 1363 AGAQALEKLEAA 1374
Score = 33.1 bits (74), Expect = 2.4
Identities = 95/384 (24%), Positives = 124/384 (32%), Gaps = 63/384 (16%)
Query: 35 RAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGP--LAELPSARKMNMLAGPQPYGG 92
+A PP +P +P A L P P P GP LA P + + +
Sbjct: 1085 QALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRL-------SP 1137
Query: 93 SKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPA 152
SK P P E E E + G E PPL P P +A A PA
Sbjct: 1138 SKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESP----LPLPAAEAMATPSPA 1193
Query: 153 SERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRT----YGTTTAP 208
+ L+ Q E PD + G D R P T G P
Sbjct: 1194 GGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRV--DSPGRTEPCTAALDLGVQLTP 1251
Query: 209 RDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADIS 268
TL ++E PV+ P P ++P + LA+ A SE S
Sbjct: 1252 -----ETLVE--AKEEPVEVPV-------AVPVVEAVPEE-----GLAQVAPSE-----S 1287
Query: 269 KPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQA 328
+P + S G P EA P S C + + S
Sbjct: 1288 QPTLEMSDCDVPAGEGQCPSLEPQEA-----------VPVLGSTCFLEEASSDQFLPSLE 1336
Query: 329 SPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSP 388
P + A +A LP +R PSPG A GA + + VLE L S
Sbjct: 1337 DPLAGMNALAAAAELPQ--ARPLPSPG--AAGAQALEKLEAAESLVLEQSFLHGITLLS- 1391
Query: 389 RPLIEVGELLDLTRTFPSGGEEEA 412
E+ EL R+ GG E A
Sbjct: 1392 ----EIAELELERRSQEMGGAERA 1411
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 64.7 bits (156), Expect = 7e-10
Identities = 137/575 (23%), Positives = 208/575 (36%), Gaps = 70/575 (12%)
Query: 235 EHSKTPEERSLPSDLAFNGDLAKAASSELPA--DISKPWIPSSPAPSSENGGPASPGLPA 292
E PE + + A GD +A P D+ P P SE+
Sbjct: 1841 EGEAQPESEGVEAPEA-EGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEV 1899
Query: 293 EASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTP 352
+ G +P + + LE + + ++ A A AA EG
Sbjct: 1900 QPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEA--QEAEEAAQEAEGQTQPE 1957
Query: 353 SPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEA 412
S + ++ A E +P S E LE Q +P E D+ G +EA
Sbjct: 1958 SEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQP-----ESEDVEAPEAEGEMQEA 2012
Query: 413 KGDAHLRPTSLVQRRFSEG-VLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWS 471
+ +A + + SEG Q + +K G A P+ G + E+
Sbjct: 2013 EEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGD--AQPESDGVEAPEAEEEAQEAEGE 2070
Query: 472 LSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSRE-EGVSQQGQG 530
+ ++ ++ P S +A EA A+ + V + E EG +Q+ +G
Sbjct: 2071 VQEA---------------EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEG 2115
Query: 531 AGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPL-----EPLPTTEGTPGLPLQQ 585
AP G + + + + +GE+QP+ V E P +E G+ Q+
Sbjct: 2116 I-EAPETEGEAQPESEGIE---APEAEGEAQPESEGVEAQDAEGEAQPESE---GIEAQE 2168
Query: 586 AEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPD--QPCVLFADAPEPGQA 643
AEE E+Q L G E+P A P E G E P A QP + +APE +
Sbjct: 2169 AEE--EAQPELEGVEAP---EAEGEAQPESE---GIEAPEAEGEAQPELEGVEAPEAEEE 2220
Query: 644 LPVEEEAVTLARAE---TTQARTEAQDLCRASPE--------PPGPESSSRWLDDLLASP 692
E E V AE ++ E Q + SP+ ESSS +D +P
Sbjct: 2221 AQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPED-RPTP 2279
Query: 693 PPSGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSE--FGITGDPQPSSFSPSSWCQ 750
PPS GG + S S S W QKD +++ G T P S +
Sbjct: 2280 PPSPGGDTPHQRPGSQTGPSSSRASSWGNCW-QKDSENDHVLGDTRSPDAKSTGTPHAER 2338
Query: 751 GASQDYGLGGASPRGDPGLGERDWTSKYGQGAGEG 785
A++ Y S + + LG R QGA EG
Sbjct: 2339 KATRMYPESSTSEQEEAPLGSR----TPEQGASEG 2369
Score = 52.8 bits (125), Expect = 3e-06
Identities = 152/713 (21%), Positives = 253/713 (35%), Gaps = 130/713 (18%)
Query: 393 EVGELLDLTRTFPSGGE--EEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAAL 450
++ ++L R + GE E A G H PTS + +EG L P Q G +
Sbjct: 1688 DLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGL-GPGLSQ---GPGVDEG 1743
Query: 451 PQGQGSQLA---LDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAA 507
G+GSQ D G +++Q E + G SE
Sbjct: 1744 EDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAG---------------SELG 1788
Query: 508 EAAEAGNLAVSSREEGVSQQG----QGAGSAPSGSGSSWVQGD-DPSMSLTQKG------ 556
EA + G EG+S++G QG+G + G + GD DP S +G
Sbjct: 1789 EAEQEG--------EGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEA 1840
Query: 557 DGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILE 616
+GE+QP+ V P EG Q+AE
Sbjct: 1841 EGEAQPESEGV---EAPEAEG----DAQEAE----------------------------- 1864
Query: 617 PVLGQEQPAAPDQPCVLFADAPE-PGQALPVEEEAVTLARAETTQARTEAQDLCRASPEP 675
G+ QP + D +APE G+A P E+ ET +A E Q + E
Sbjct: 1865 ---GEAQPESED------VEAPEAEGEAQPESED------VETPEAEWEVQPESEGA-EA 1908
Query: 676 PGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGIT 735
P E ++ + + + G GAE ++ + + +EG + ++S+
Sbjct: 1909 PEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ-EAE 1967
Query: 736 GDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQGAGEGSTREWASRCG 795
+ QP S + G A P + D + +G + + E A
Sbjct: 1968 EEAQPESEDVEALEVEVETQEAEGEAQPESE------DVEAPEAEGEMQEAEEE-AQPES 2020
Query: 796 IGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTY 855
G E S ++ +V T D + +EA + E ++ + +
Sbjct: 2021 DGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHP 2080
Query: 856 SSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQDANE-----QGQDLG 910
S D + Q+ E + S V + E + + G A + E +G +
Sbjct: 2081 ESEDVDAQEAEGEAQP-----ESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135
Query: 911 KRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEF-GKSAWIRDYSSGGSSRT 969
+ + + S+ + QD E + + S G A E + E G A + + S
Sbjct: 2136 EAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEG 2195
Query: 970 LDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPGERGSGGLFS 1029
++A + +P G EA + +EE + + VE EG GE S
Sbjct: 2196 IEAPEAEGEAQPELEGV---EAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGS 2252
Query: 1030 PSTAHVPDGALGQRDQSSWQNSDASQE-------VGGHQERQQAGAQ-GPGSA 1074
P + + D GQ +++S +S ++ GG Q+ G+Q GP S+
Sbjct: 2253 PQVS-LGD---GQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSS 2301
Score = 37.4 bits (85), Expect = 0.13
Identities = 76/382 (19%), Positives = 132/382 (34%), Gaps = 66/382 (17%)
Query: 750 QGASQDYGLGGASPRG-----DPGLGERDWTSKYGQGAGEGSTREWASRCGIGQEEMEAS 804
QG D G G + DP LGE + + + G+ E ++ +G+ E E
Sbjct: 1736 QGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGE 1795
Query: 805 SSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEAD-VQDWEFRKRDSQGTYSSRDAELQ 863
++ + G +D + G+ A G Q ++D + E + + + S E
Sbjct: 1796 GISERGETGGQG-SGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAP 1854
Query: 864 DQEFGKRDSLGTY--SSRDVSLGDWEFGKRDSLGAYASQDANEQGQDLGKRDHHGRYSSQ 921
+ E +++ G S DV + A +A + +D+
Sbjct: 1855 EAEGDAQEAEGEAQPESEDVEAPE------------AEGEAQPESEDV------------ 1890
Query: 922 DADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRDYSSGGSSRTLD---------- 971
+ E +WE Q + G+ A E +++ ++ + + G
Sbjct: 1891 ETPEAEWEVQPE-----SEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945
Query: 972 -AQDRSFGTRP----LSSGFSPEEAQQQDEEFEKKIPSVEDSLGEG-----SRDAGRPGE 1021
AQ+ T+P + S + EEAQ + E+ E VE EG S D P
Sbjct: 1946 AAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEA 2005
Query: 1022 RGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQ----GPGSADLE 1077
G DG Q + +QEV G ++ + AQ G + + E
Sbjct: 2006 EGEMQEAEEEAQPESDGVEAQPK----SEGEEAQEVEGETQKTEGDAQPESDGVEAPEAE 2061
Query: 1078 DGEMGKRGWVGEFSLSVGPQRE 1099
+ G V E P+ E
Sbjct: 2062 EEAQEAEGEVQEAEGEAHPESE 2083
Score = 37.0 bits (84), Expect = 0.17
Identities = 116/573 (20%), Positives = 185/573 (32%), Gaps = 61/573 (10%)
Query: 991 AQQQDEEFEKKIPSVEDSLGEGSRDAGRPGERG-SGGLFSPSTAHVPDGALGQRDQSSWQ 1049
AQ+++ + S LGE ++ ERG +GG S ++ A DQ Q
Sbjct: 1769 AQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQ 1828
Query: 1050 NSDA----SQEVGGHQERQQAGAQGP---GSADLEDGEMGKRGWVGEFSLSVGPQREAAF 1102
+ A + E G + + G + P G A +GE E P+ E
Sbjct: 1829 SDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVE-----APEAEGEA 1883
Query: 1103 SPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPSSKMEGGHFVPPGKTTAGSVDWT 1162
P +D +E E ++ P S EG K +
Sbjct: 1884 QPESED------VETPEAEWEV-------------QPES--EGAEAPEAEKEAQPETESV 1922
Query: 1163 DQLGLRNLEVSSCVGSGG--SSEARESAVGQMGWSGGLSLRDMNLTGCLESGGSEEPGGI 1220
+ L + G+ + EA + A GQ + E +
Sbjct: 1923 EALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEV 1982
Query: 1221 GVGEKDWTSDVNVKSKDL------AEVGEGGGHSQARESGV-GQTDWSGVEAGEFLKSRE 1273
V ++ + +S+D+ E+ E +Q GV Q G EA E +
Sbjct: 1983 EVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQ 2042
Query: 1274 RGVGQADWTPD-LGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDPDSGG-- 1330
+ G A D + A + GE +E ++ ++ E P+S G
Sbjct: 2043 KTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVE 2102
Query: 1331 -------SQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRHNGS 1383
+Q G + + + +E A EA+ G +Q E +
Sbjct: 2103 APEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPE-- 2160
Query: 1384 LSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASPGRC 1443
S G+EA++ E + + PE +GE S P G E A
Sbjct: 2161 -SEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEE 2219
Query: 1444 PARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDS 1503
A+P P G + E A S+ + E S L G G E P +
Sbjct: 2220 EAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSL----GDGQSEEASESSSPVPED 2275
Query: 1504 PPSWRPQPDGEASQTEDVDGTWGSSAARWSDQG 1536
P+ P P G+ T G S++R S G
Sbjct: 2276 RPTPPPSPGGDTPHQRPGSQT-GPSSSRASSWG 2307
Score = 36.6 bits (83), Expect = 0.22
Identities = 165/742 (22%), Positives = 242/742 (32%), Gaps = 133/742 (17%)
Query: 172 RKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDG-STLFRGWSQEGPVKSPA 230
R E AS D S T +H+GSS +G R G R E G P S +
Sbjct: 526 RSEEGASSD---SSASTGSHEGSSEWGGRPQGCPGKARAETSQQEASEGGDPASPALSLS 582
Query: 231 ECREEHSKTPEE--------------RSLPSDLAFNGDLAKAASSELPADISKPWIPSSP 276
R + + + L L+ + D A+S+ S+
Sbjct: 583 SLRSDDLQAETQGQGTEQATGAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHR 642
Query: 277 APSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLE--AQTPE---ASQASPC 331
+ +S P+SPGL A P H + D SP S + + + PE A Q
Sbjct: 643 SRASAMSSPSSPGLGRVAPRGHPRHSH-YRKDTHSPLDSSVTKQVPRPPERRRACQDGSV 701
Query: 332 PAVTPSAPSAALPDEGSRHTPSPG-LPAE-------------------------GAPEA- 364
P + S+ S G+ PS G LP++ AP A
Sbjct: 702 PRYSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAG 761
Query: 365 ------PRPSSPPPEVLEPH-----------SLDQPPATSPRP----LIEVGELLDLTRT 403
R SP P + PH SL + +P+P +++VG
Sbjct: 762 WAGDAGSRTCSPAP--IPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGR------- 812
Query: 404 FPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRP 463
E+ A G S + ++ + PS + L G P +G R
Sbjct: 813 ----PEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCGRYCPTPP-RGRPCPQRRS 867
Query: 464 FGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEG 523
S S QS P G P P+P + A + + SR G
Sbjct: 868 SSCGSTGSSHQS----TARGPGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSR--G 921
Query: 524 VSQQGQ-GAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPL-------PTT 575
+S++ +G P G + G PS + + +P EP+ T
Sbjct: 922 LSEEKTLRSGGGPQGQEEA--SGVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADET 979
Query: 576 EGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFA 635
G G L+ E L G P +A LE GQ+ P+ + +
Sbjct: 980 TGAAGGGLRGPEVDPGDDHSLEGLGEP-----AQAGQQSLEGDPGQD--PEPEGALLGSS 1032
Query: 636 D-APEPGQALP--VEEEAVTLARAETTQARTEAQDLCRASPEP-PGPESSSRWLDDLLAS 691
D P+ G+ +P E V+ A AE R EA CR S PG S+S + L
Sbjct: 1033 DTGPQSGEGVPQGAAPEGVSEAPAEAGADR-EAPAGCRVSLRALPGRVSASTQIMRALM- 1090
Query: 692 PPPSGGGARRGAGAELKDTQSPS----TCSEGLLGWSQKDLQSEFGITGDPQPS-SFSPS 746
G+++G + + + P +CS G L LQ G P F S
Sbjct: 1091 ------GSKQGRPSSVPEVSRPMARRLSCSAGALITCLASLQLFEEDLGSPASKVRFKDS 1144
Query: 747 SWCQ---GASQDY--GLGGASPRGDPGLGERDWTSKYGQGAGEGSTREWASRCGIGQEEM 801
Q S+D G + D GL E W+ T + G +
Sbjct: 1145 PRYQELLSISKDLWPGCDVGEDQLDSGLWELTWSQALPDLGSHAMTENFTPTSSSGVDIS 1204
Query: 802 EASSSQDQSKV--SAPGVLTAQ 821
S +S V + G L Q
Sbjct: 1205 SGSGGSGESSVPCAMDGTLVTQ 1226
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 63.9 bits (154), Expect = 1e-09
Identities = 198/817 (24%), Positives = 250/817 (30%), Gaps = 146/817 (17%)
Query: 31 PGDTRAKPPVKPKPRALPAKPALPAKPS------------LLVPVGPRPPRGPLAELPSA 78
PG+ A P + PR LP + P P P GP P GP P A
Sbjct: 292 PGENGA--PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG-FPGA 348
Query: 79 RKMNMLAGPQPYGGSKRPL-----PFAPRPAVEASTGGEATQETGKEEAGKEEPP----- 128
AGPQ GS+ P P P PA A G + G P
Sbjct: 349 VGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA 408
Query: 129 PLTPPARC-AAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRL 187
P P AR + P G P P + E A + + AK E P + P G
Sbjct: 409 PGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE-PGPVGVQGPPGPAGEEG 467
Query: 188 TFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPS 247
G GP R GS F G K PA ER P
Sbjct: 468 KRGARGEP--GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG----------ERGSPG 515
Query: 248 DLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPP 307
G P + +P P G P SPG + GP P
Sbjct: 516 PAGPKGS---------PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPG 566
Query: 308 DKSSP---CHSQLLEAQTPEASQASPCPA---VTPSAPSAALP-----DEGSRHTPSPGL 356
P + ++ P+ + P A P P A P + G++ P P
Sbjct: 567 PPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG 626
Query: 357 PA-----------EGAPEAPRPSSPPPEVLEPHSLDQP-PATSPRPLIEVGELLDLTRTF 404
PA G P P+ PP E +P P +P P GE R F
Sbjct: 627 PAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE-----RGF 681
Query: 405 PSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPF 464
P GE +G P R + G +P D K P QG+ P
Sbjct: 682 P--GERGVQG-----PPGPAGPRGANG---APGNDGAKGDAGAPGAPGSQGAPGLQGMP- 730
Query: 465 GAESNWSLSQSFEWTFPTRPSGL-------GVWRLDSP--PPSPITEASEAAEAAEAGNL 515
G L P G GV L P PP P + E+ +G
Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790
Query: 516 AVSSREEGVSQQGQGAGSAPSG-SGSSWVQGDDPSMSLTQKGD----GESQPQFPAVPLE 570
+ +G+ P+G +G G + + GD G++ P PA P
Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKG--EPGDAGAKGDAGPPGPAGPAG 848
Query: 571 PLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQP 630
P P G G P + G P P AT G+ P P
Sbjct: 849 P-PGPIGNVGAP---------GAKGARGSAGP-PGATG------FPGAAGRVGPPGPS-- 889
Query: 631 CVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLA 690
+A PG P +E R ET A + P PPGP
Sbjct: 890 ----GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE---VGPPGPPGPAGEK-------G 935
Query: 691 SPPPSGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQ 750
SP GA AGA G++G + + E G G P PS
Sbjct: 936 SP-----GADGPAGAPGTPGPQGIAGQRGVVGLPGQ--RGERGFPGLPGPSGEPGKQGPS 988
Query: 751 GASQDYGLGGASPRGDPGL-GERDWTSKYGQGAGEGS 786
GAS + G G P G PGL G + + G EGS
Sbjct: 989 GASGERGPPG--PMGPPGLAGPPGESGREGAPGAEGS 1023
Score = 53.1 bits (126), Expect = 2e-06
Identities = 215/917 (23%), Positives = 276/917 (30%), Gaps = 157/917 (17%)
Query: 21 EEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGP--------- 71
++E GDT + P P P + +P +P L P GP P GP
Sbjct: 104 DQETTGVEGPKGDTGPRGP--RGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAP 161
Query: 72 -LAELPSARKMNMLAGPQPYGGS-KRPL---PFAPRPAVEASTGGEATQETGKEEAGKEE 126
L+ + ++ P P G S R L P AP P GE + G
Sbjct: 162 QLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRG 221
Query: 127 PPPLTPPAR------CAAPG--GVRKAPAP----FRPASERFAATTVEEILAKMEQPRKE 174
PP PP + PG G R P P P + + ++ + +
Sbjct: 222 PP--GPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGD 279
Query: 175 VLASPDRLWGSRLTFNHDGS-SRYGPR----TYGTTTAP-----RDEDGSTLFRG----W 220
A P G + +G+ + GPR G AP R DG+T G
Sbjct: 280 --AGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT 337
Query: 221 SQEGPVKSPAECREEHSKTPE-ERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPS 279
GP P + P+ R G+ + P P
Sbjct: 338 GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAK 397
Query: 280 SENGGP---ASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVT- 335
NG P +PG P SGP P P K + ++ ++ P P
Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ 457
Query: 336 -PSAPSAALPDEGSRHTPSP-GLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATS-PRPLI 392
P P+ G+R P P GLP PP E P S P A P
Sbjct: 458 GPPGPAGEEGKRGARGEPGPTGLP-----------GPPGERGGPGSRGFPGADGVAGPKG 506
Query: 393 EVGELLDLTRTFPSG--GEEEAKGDAHL-RPTSLVQRRFSEGV-----LQSPSQDQEKLG 444
GE P G GE G+A L L S G P+ + G
Sbjct: 507 PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPG 566
Query: 445 GSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSP-----PPSP 499
+GQ + P GA ++ E P P +G D PP P
Sbjct: 567 PPGPPGARGQAGVMGFPGPKGAAG--EPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624
Query: 500 ITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGS----GSSWVQGD----DPSMS 551
A E E AG+ QG + P G G V GD PS +
Sbjct: 625 AGPAGERGEQGPAGSPGF---------QGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGA 675
Query: 552 LTQKG-DGESQPQFPAVPLEPLPTT-----------EGTPGLPLQQAEERYESQEPLAGQ 599
++G GE Q P P P G PG P Q + G
Sbjct: 676 RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA 735
Query: 600 ES-PLPLATREAA-------LPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAV 651
P P R A P + V G P P P D E G + P
Sbjct: 736 AGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGP------ 789
Query: 652 TLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPP-----PSGGGARRGAGAE 706
A T AR D R P PPGP A PP P G AGA+
Sbjct: 790 ----AGPTGARGAPGD--RGEPGPPGPAG--------FAGPPGADGQPGAKGEPGDAGAK 835
Query: 707 LKDTQSPSTCS----EGLLG-WSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGA 761
D P G +G + G G P + F ++ G G A
Sbjct: 836 -GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP--SGNA 892
Query: 762 SPRGDPG-LGERDWTSKYGQGAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGV--- 817
P G PG G+ G+ G E G + S D APG
Sbjct: 893 GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD-GPAGAPGTPGP 951
Query: 818 --LTAQDRVVGKPAQLG 832
+ Q VVG P Q G
Sbjct: 952 QGIAGQRGVVGLPGQRG 968
Score = 43.5 bits (101), Expect = 0.002
Identities = 84/345 (24%), Positives = 107/345 (31%), Gaps = 53/345 (15%)
Query: 44 PRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSK-----RPLP 98
P+ P L P+GP P G P + + +GP G++ R P
Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPAGA----PGDKGESGPSGPAGPTGARGAPGDRGEP 805
Query: 99 FAPRPAVEASTGGEATQETGKEEAG----KEEPPPLTPPARCAAPGGVRKAPAPFRPASE 154
P PA A G Q K E G K + P P PG + AP +
Sbjct: 806 GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGAR 865
Query: 155 RFA----ATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRD 210
A AT ++ P A P GP PR
Sbjct: 866 GSAGPPGATGFPGAAGRVGPPGPSGNAGPP--------------GPPGPAGKEGGKGPRG 911
Query: 211 EDGSTLFRGWSQEGPVKSPAECREEHSKTPE-ERSLPSDLAFNGDLAKAASSELPADISK 269
E G G + GP P E+ S + P G + LP +
Sbjct: 912 ETGPAGRPG--EVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGE 969
Query: 270 PWIPSSPAPSSENGGPASPGLPAEASGSGP-GSPHL-HPPDKSSPCHSQLLEAQTPEASQ 327
P P PS E G G E GP G P L PP +S + ++
Sbjct: 970 RGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESG--------REGAPGAE 1021
Query: 328 ASPCPAVTPSAPSAALPDEGSRHTPSPGLP--AEGAPEAPRPSSP 370
SP +P A +G R P P A GAP AP P P
Sbjct: 1022 GSPGRDGSPGA-------KGDRGETGPAGPPGAPGAPGAPGPVGP 1059
Score = 42.7 bits (99), Expect = 0.003
Identities = 144/598 (24%), Positives = 185/598 (30%), Gaps = 119/598 (19%)
Query: 1017 GRPGERG----SGGLFSPSTAHVP-----------DGALGQRDQSSWQNSDASQEVGGHQ 1061
GRPGERG G P TA +P DGA G + + S G
Sbjct: 239 GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298
Query: 1062 ----------ERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSR 1111
ER + GA GP A DG G G G GP F PG
Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG----PTGPAGPPGF-PG------ 347
Query: 1112 DFCIEASERSYQFGIIGNDRVSGAGFSPSSKMEGGHFVPPGKTTAGSVDWTDQLGLRNLE 1171
+ A + G G++ G P G P G A Q G +
Sbjct: 348 --AVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADG-----QPGAKGAN 400
Query: 1172 VSSCVGSGGSSEARESAVGQMGWSG-----GLSLRDMNLTGCLESGGSEEPGGIGVGEKD 1226
+ + G G G G S ++G EPG +GV
Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460
Query: 1227 WTSDVNVKSKDLAEVGEGGGHSQARE-SGVGQTDWSGVE--AGEFLKSRERGVGQADWTP 1283
+ K E G G E G G + G + AG + ERG +P
Sbjct: 461 GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG------SP 514
Query: 1284 DLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQMD 1343
+PG PGE+ G + T P S G G G
Sbjct: 515 GPAGPKGSPGEAGRPGEAGLPGAKGL-------------TGSPGSPGPDGKTG---PPGP 558
Query: 1344 WTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEARELGV-G 1402
QD P G P G GV P P G+ A +P +A E GV G
Sbjct: 559 AGQDGRP------GPPGPPGARGQAGVMGFPGP----KGA------AGEPGKAGERGVPG 602
Query: 1403 ETSGPETQGEDYSSSSL-EPHPADPGMETGE-----ALSFGASPGRCPARPP----PSGS 1452
G+D + + P PA P E GE + F PG PA PP G
Sbjct: 603 PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG--PAGPPGEAGKPGE 660
Query: 1453 QGLLEEMLAASSSKAVARR----ESAASGLGGLLEEEGAGAGAAQEEVL-------EPGR 1501
QG+ ++ A S A R E G G GA + PG
Sbjct: 661 QGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGS 720
Query: 1502 DSPPSWRPQP-DGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGP-----PARSP 1553
P + P + A+ G G + + +D P + R GP PA +P
Sbjct: 721 QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778
Score = 41.6 bits (96), Expect = 0.007
Identities = 138/567 (24%), Positives = 180/567 (31%), Gaps = 55/567 (9%)
Query: 1016 AGRPGERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQ-EVGGHQERQQAGAQGPGSA 1074
AG PG G+ G PS P G G + S + S+ + G E G QGP
Sbjct: 406 AGAPGFPGARG---PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGP 462
Query: 1075 DLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSG 1134
E+G+ G RG G L GP E PG + + + + G G+ +G
Sbjct: 463 AGEEGKRGARGEPGPTGLP-GPPGERG-GPGSRGFPGADGVAGPKG--PAGERGSPGPAG 518
Query: 1135 AGFSPSSKMEGGHFVPPG-KTTAGSVDWTDQLGLRN----LEVSSCVGSGGSSEARESAV 1189
SP G PG K GS G G G AR A
Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA- 577
Query: 1190 GQMGWSGGL-SLRDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHS 1248
G MG+ G + + G E G PG +G KD + GE G
Sbjct: 578 GVMGFPGPKGAAGEPGKAG--ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG 635
Query: 1249 QARESGVGQTDWSGVEAGEFLKSRERGV-GQADWTPDLGLRNM-----APGAVCSPGESK 1302
A G GE K E+GV G G R G PG +
Sbjct: 636 PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695
Query: 1303 ELGVGQMDWGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEA 1362
G GN+ D P S G+ GL+G M + A L G +
Sbjct: 696 PRGANGAP-GNDGAKGDAGAPGAPGSQGAPGLQG-----MPGERGAA----GLPGPKGDR 745
Query: 1363 REHGVGGVSQCP-EPGLRH-NGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLE 1420
+ G G P + G+R G + P A P + E G +GP T E
Sbjct: 746 GDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGP-TGARGAPGDRGE 804
Query: 1421 PHPADPGMETGEALSFG-----ASPGRCPAR-----PPPSGSQGLLEEMLAASSSKAVAR 1470
P P P G + G PG A+ P P+G G + + A
Sbjct: 805 PGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGA 864
Query: 1471 RESA----ASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWG 1526
R SA A+G G G + G PP + G+ + E
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSG-----NAGPPGPPGPAGKEGGKGPRGETGPAGRP 919
Query: 1527 SSAARWSDQGPAQTSRRPSQGPPARSP 1553
GPA P PA +P
Sbjct: 920 GEVGPPGPPGPAGEKGSPGADGPAGAP 946
Score = 36.2 bits (82), Expect = 0.28
Identities = 41/129 (31%), Positives = 47/129 (36%), Gaps = 11/129 (8%)
Query: 988 PEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPGERGSGGLFSPSTAHVPDGALG------ 1041
P A E + P E S G G G+RG G P A GA G
Sbjct: 1003 PGLAGPPGESGREGAPGAEGSPGRDG-SPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAG 1061
Query: 1042 -QRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGEMGKRGWVGE--FSLSVGPQR 1098
D+ + + VG R AG QGP E GE G RG G FS GP
Sbjct: 1062 KSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPG 1121
Query: 1099 EAAFSPGQQ 1107
SPG+Q
Sbjct: 1122 PPG-SPGEQ 1129
Score = 35.0 bits (79), Expect = 0.63
Identities = 28/102 (27%), Positives = 32/102 (31%), Gaps = 17/102 (16%)
Query: 283 GGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAA 342
G P SPG + SGP P P +P L P + P P
Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP----------IGPPGPRGR 1170
Query: 343 LPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPP 384
D G P P P P P PP + L QPP
Sbjct: 1171 TGDAGPVGPPGP-------PGPPGPPGPPSAGFDFSFLPQPP 1205
Score = 34.7 bits (78), Expect = 0.83
Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 2/76 (2%)
Query: 1013 SRDAGRPGERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPG 1072
S D G G G G P A P G G R + + GH R +G QGP
Sbjct: 1063 SGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGH--RGFSGLQGPP 1120
Query: 1073 SADLEDGEMGKRGWVG 1088
GE G G G
Sbjct: 1121 GPPGSPGEQGPSGASG 1136
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 62.4 bits (150), Expect = 4e-09
Identities = 225/1115 (20%), Positives = 372/1115 (33%), Gaps = 127/1115 (11%)
Query: 661 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGL 720
+ T Q AS GP S+SR + SG G+R + + +
Sbjct: 1520 SHTTPQGRSDASHGQSGPRSASRQT----RNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQ 1575
Query: 721 LGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQD------------YGLGGASPRGDPG 768
+G + S T Q SS S +G S+D YG S R
Sbjct: 1576 VGQGE----SAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYG----SAREQSR 1627
Query: 769 LGERDWTSKYGQGAGEGSTREWASRCGIGQEEM----EASSSQDQSKVSAPGVL--TAQD 822
G R+ S A G + E + + G E +A+SSQ+Q++ S+PG +
Sbjct: 1628 HGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQAR-SSPGERHGSRHQ 1686
Query: 823 RVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTYSS----RDAELQDQEFGKRDSLGTYSS 878
+ GT R Q++ V + R S G+ +S E Q G +
Sbjct: 1687 QSADSSTDSGTGRRQDSSVVG-DSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQ 1745
Query: 879 RDVSLGDWEFGKRDSL-GAYASQDANEQ---------GQDLGKRDHHGRYSSQDADEQDW 928
+ G+R G++ Q + + G G R ++D+
Sbjct: 1746 SHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSA 1805
Query: 929 EFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSP 988
+ +D G GS Q + +S +S S T +Q+RS +S G S
Sbjct: 1806 SQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTT-SQERS----DVSRGQSG 1860
Query: 989 EEAQQQDEEFEKKIPSVEDSLGEGSR--------DAGRPGERGSGGLFSPSTAHVPDGAL 1040
+ + EK+ S + S GSR D+ R + G G P T+ ++
Sbjct: 1861 SRSVSRQTRNEKQ--SGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSV 1918
Query: 1041 GQ--------RDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGEMGKRGWVGEFSL 1092
Q D W S + +G E+ + G++ PGS + G + S
Sbjct: 1919 SQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGS---HHEDRAGHGHSADSSR 1975
Query: 1093 SVGPQREAAFSPGQ----QDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPSSK--MEGG 1146
G + + S GQ + +R E +Q + R SG G +S + G
Sbjct: 1976 QSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSG 2035
Query: 1147 HFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSLRDMNLT 1206
H G + S ++ +++ G S +ESA GQ G
Sbjct: 2036 HRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSH-KESARGQSG------------- 2081
Query: 1207 GCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDWSGVEAG 1266
ES G V + + + +S +G + QA++S G +
Sbjct: 2082 ---ESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTI 2138
Query: 1267 EFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDP 1326
RG Q R+ G+ S S+ G G + T D
Sbjct: 2139 RGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQ--GRSDASRGQSGSRSASRKTYDK 2196
Query: 1327 DSGGSQGLRGCGVGQMDWTQDLAPQNVELFG-----APSEAREHGVGGVSQCPEPGLRHN 1381
+ G G R G + + L G P +R G G +
Sbjct: 2197 EQSG-DGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSED 2255
Query: 1382 GSLSPGLEARDPL-EARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASP 1440
G +R+ A+E + P + ED + H A+ ++G + +S
Sbjct: 2256 SERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG---HSAESSRQSGTHHAENSSG 2312
Query: 1441 GRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPG 1500
G+ + + S +A ++SA S G G G A V + G
Sbjct: 2313 GQAASSHEQARS--------SAGERHGSHHQQSADSS-----RHSGIGHGQASSAVRDSG 2359
Query: 1501 -RDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSF 1559
R S S +G S+ D A Q +++R S G RS S +
Sbjct: 2360 HRGSSGSQASDSEGH-SEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ- 2417
Query: 1560 IEDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVP 1619
+ E +SA R+ + G ++G R S+ H S+ R
Sbjct: 2418 VSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSS--GGRQG 2475
Query: 1620 SSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQ 1679
S E++V+ + S T + + G S S ++ R + G+ + S+
Sbjct: 2476 SHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGS--RSASRQTRNDEQSGDGSRHSGSR 2533
Query: 1680 KESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGS 1714
A R+ S +G+ + P+ ++ GS S
Sbjct: 2534 HHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFS 2568
Score = 53.5 bits (127), Expect = 2e-06
Identities = 229/1132 (20%), Positives = 369/1132 (32%), Gaps = 187/1132 (16%)
Query: 657 ETTQARTEAQDLCRASPEPPGPESS--SRWLDDLLASPPPSGGGARRGAGAEL---KDTQ 711
+TT + E + S G SS +R + + P R+ G+ + +D++
Sbjct: 245 DTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSE 304
Query: 712 SPSTCSEGLLGWSQKDLQS---EFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPG 768
S SE G + ++ E G P S G S D + +
Sbjct: 305 GHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAE-- 362
Query: 769 LGERDWTSKYGQGAG--EGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVG 826
TS GQ A E + R G G ++ S D S+ SA G A V
Sbjct: 363 ------TSSRGQTASSHEQARSSPGERHGSGHQQ-----SADSSRHSATGRGQASSAVSD 411
Query: 827 KPAQLGTQRSQEADVQDWEFRKRDSQGTYSSRDAELQDQEFGK--RDSLGTYSSRDVSLG 884
+ G+ SQ +D + D+Q A L+ Q + R G S R S
Sbjct: 412 R-GHRGSSGSQASD-SEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGS-S 468
Query: 885 DWEFGKRDSLGAYASQDANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRA 944
++ + + + G G R SS+ + Q+ + R + G R
Sbjct: 469 LYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQ 528
Query: 945 AEPQEQEFGKSAWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPS 1004
EQ +S SG +Q RS + S S + +E+ S
Sbjct: 529 GSHHEQSVNRSG-----HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQ------S 577
Query: 1005 VEDSLGEGSR--------DAGRPGERGSGGLFSPSTAHVPDGALGQ--------RDQSSW 1048
+ + GSR D+ R + G G P T+ ++ Q D W
Sbjct: 578 GDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERW 637
Query: 1049 QNSDASQEVGGHQERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQ-- 1106
S + G QE+ + G++ P S + G + S G + S GQ
Sbjct: 638 SGSASRNHHGSAQEQSRDGSRHPRS---HHEDRAGHGHSADSSRKSGTRHTQNSSSGQAA 694
Query: 1107 --QDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPSSK--MEGGHFVPPGKTTAGSVDWT 1162
+ +R E +Q + R SG G +S + GH G S +
Sbjct: 695 SSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHS 754
Query: 1163 --------------------------DQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSG 1196
D+ G R+ S + + + ES+ G G S
Sbjct: 755 EDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPST 814
Query: 1197 GL-------SLRDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQ 1249
G+ RD + + G G G + + +S D + G G H
Sbjct: 815 GVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRS--GHSGSH-H 871
Query: 1250 ARESGVGQTDWSGVEAGEFLKSR-ERGVGQA-DWTPDLGLRNMAPGAVCSPGESKELGVG 1307
+ + G++D S ++G SR R Q+ D + G R+ + + G G
Sbjct: 872 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQG 931
Query: 1308 QMDWGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGV 1367
Q + + V+ D DS G SE E
Sbjct: 932 QSEGSRTSRRQGSSVSQDSDSEGH----------------------------SEDSERWS 963
Query: 1368 GGVSQCPEPGLRHNGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPG 1427
G S+ H GS A+E + P + ED + H AD
Sbjct: 964 GSASR------NHRGS------------AQEQSRHGSRHPRSHHEDRAGHG---HSADSS 1002
Query: 1428 METGEALSFGASPGRC-----PARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLL 1482
++G + +S G+ AR P G + A SS + R A+S +
Sbjct: 1003 RQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSG 1062
Query: 1483 EEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSR 1542
+G+ A+ E E S T+ V G + S Q +++R
Sbjct: 1063 HWGSSGSQASDSE---------------GHSEESDTQSVSGHGQDGPHQQSHQ---ESAR 1104
Query: 1543 RPSQGPPARSPSQDFSFIEDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADS 1602
S G RS S + + E +SA R+R + GR++G R S+
Sbjct: 1105 DWSGGRSGRSGSFIYQ-VSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQD 1163
Query: 1603 DAHLFQDSTEPRASRVPSSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRP 1662
S R R S E+ V+ + S T + + G S S ++ R
Sbjct: 1164 TIRAHPGSR--RGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGS--RSASRQ 1219
Query: 1663 RNRSAEEGELAESKSSQKESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGS 1714
+ + G+ + S+ A + S + +G+ E+SSGS S
Sbjct: 1220 TRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQ--------EQSSGSRTS 1263
Score = 48.5 bits (114), Expect = 6e-05
Identities = 210/1006 (20%), Positives = 328/1006 (32%), Gaps = 153/1006 (15%)
Query: 274 SSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPA 333
SS +S++G G P + G G H H D S S + S AS +
Sbjct: 2773 SSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQS 2832
Query: 334 VTPSAPSAALPDE----GSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATS-P 388
+ SA +E GSRH+ S A + R S E + +S
Sbjct: 2833 GSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVS 2892
Query: 389 RPLIEVGELLDLTRTFPS------GGEEEAKGDAHLRPTSLVQRRFSEG-----VLQSPS 437
+ G D R S G +E D P S + R G QS +
Sbjct: 2893 QDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGT 2952
Query: 438 QDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPP 497
+ + G AA Q A +R G+ S S R SG+G + S
Sbjct: 2953 RHTQTSSGGQAASSHEQARSSAGER-HGSHHQQSADSS-------RHSGIGHGQASSAVR 3004
Query: 498 SPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAG-------SAPSGSGSSWVQGDDPSM 550
++A++ + S + VS GQ SA SG +
Sbjct: 3005 DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 3064
Query: 551 SLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREA 610
++ ES + P+T G G +QA++ GQ++
Sbjct: 3065 QVSTHEQSESSHGWTG------PSTRGRQGSRHEQAQDSSRHSASQYGQDT--------- 3109
Query: 611 ALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCR 670
+ G + + Q E + + + + T +Q
Sbjct: 3110 -------IRGHPGSSRGGR------------QGYHHEHSVDSSGHSGSHHSHTTSQGRSD 3150
Query: 671 ASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGA--ELKDTQSPSTCSEGLLGWSQKDL 728
AS G S+SR + SG +R E S S+ + G S+
Sbjct: 3151 ASRGQSGSRSASR----TTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSR 3206
Query: 729 QSEFGITGDPQPSSFSPSSWCQGASQDYGL-GGASPRGDPGL-------GERDWTSKYGQ 780
+S Q SS S S +G S+D G++ R G G R S +
Sbjct: 3207 RSR------RQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHED 3260
Query: 781 GAGEGSTREWASRCGIGQEEM----EASSSQDQSKVSAPGVL--TAQDRVVGKPAQLGTQ 834
AG G + + + + G E +A+SS +Q++ S+PG + + G
Sbjct: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHEQAR-SSPGERHGSRHQQSADSSRHSGIP 3319
Query: 835 RSQEA----DVQDWEFRKRDSQGTYSSRDAELQD-QEFGKRDSLGTYS-SRDVSLGDWEF 888
R Q + D + W SQ + S +E D Q G + S S D
Sbjct: 3320 RGQASSAVRDSRHWG--SSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSG 3377
Query: 889 GKRDSLGAYASQ-DANEQGQDL--------GKRDHHGRYSSQDADEQDWEFQKRDVSLGT 939
G+ G++ Q +EQ + G+R ++D+ + +D G
Sbjct: 3378 GRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGH 3437
Query: 940 YGSRAAEPQEQEFGKSAWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFE 999
GS Q + +S +S S T +Q RS +R S S + DE+
Sbjct: 3438 PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTT-SQGRSDASRGQSGSRSASRQTRNDEQS- 3495
Query: 1000 KKIPSVEDSLGEGSR-------------DAGRPGERGSGGLFSPSTAHVPDGALGQ---- 1042
G+GSR D+ R + G G P T+ ++ Q
Sbjct: 3496 ----------GDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDS 3545
Query: 1043 ----RDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQR 1098
D W S + G QE+ + G++ P S + G E S G
Sbjct: 3546 QGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTS---HHEDRAGHGHSAESSRQSGTHH 3602
Query: 1099 EAAFSPGQQDWSRDFC-IEASER--SYQFGIIGNDRVSGAGFSPSSK--MEGGHFVPPGK 1153
S GQ S + A ER S+ + R SG G +S + GH G
Sbjct: 3603 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGS 3662
Query: 1154 TTAGSVDWTDQLGLRNLEVSSCVGSGGSS---EARESAVGQMGWSG 1196
+ S ++ +++ G S R + G+ G SG
Sbjct: 3663 QASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 3708
Score = 40.0 bits (92), Expect = 0.020
Identities = 131/618 (21%), Positives = 203/618 (32%), Gaps = 79/618 (12%)
Query: 676 PGPESSSRWLDDLLASPPPSGGGARRGAGAELKDT----QSPSTCSEGLLGWSQKDLQSE 731
PG SR A G RR A + ++D+ S S S+ + D QS
Sbjct: 1029 PGERHGSRHQQS--ADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQS- 1085
Query: 732 FGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQGAGEGSTREWA 791
++G Q S Q +++D+ GG S R + + T + + A G TR
Sbjct: 1086 --VSGHGQDGPHQQSH--QESARDWS-GGRSGRSGSFIYQVS-THEQSESA-HGRTRTST 1138
Query: 792 SRCGIGQEEMEASSSQDQSKVSAPGVLTAQ-------------DRVVGKPAQLGTQRSQE 838
R E SS+ + + A ++ V + G+ S
Sbjct: 1139 GRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHT 1198
Query: 839 ADVQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYS-SRDVSLGDWEFGKRDSLGAY 897
+ R S G SR A Q ++ + +S SR W R S
Sbjct: 1199 TS----QGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHS---- 1250
Query: 898 ASQDANEQGQDLGKRDHHGRYSSQDADEQ----DWEFQKRDVSLGTYGSRAAEPQEQEFG 953
Q EQ H G SQD+D + D E S +GS + ++
Sbjct: 1251 --QVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRH 1308
Query: 954 KSAWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGS 1013
D +S G S Q + T S G + +Q ++ S + S
Sbjct: 1309 PGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS 1368
Query: 1014 RDAGRPGERGSGGLFSP----STAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQ 1069
R +G + S + S+ + G + S Q+ A + G HQ+ + A+
Sbjct: 1369 RHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESAR 1428
Query: 1070 GPGSADLEDGEMGKRGWVGEFSLSVGPQREA-----AFSPGQQDWSRDFCIEASERSYQF 1124
G + GE R + +S Q E+ A S G + SR S R +
Sbjct: 1429 G------QSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSR-HSA 1481
Query: 1125 GIIGNDRVSGAGFSPSSKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEA 1184
G D + G P S G G SVD + G + S G S+A
Sbjct: 1482 SQDGQDTIRG---HPGSSRGGRQ----GSYHEQSVDRSGHSGYHH----SHTTPQGRSDA 1530
Query: 1185 RESAVGQMGWSGGLSLRDMNLTGCLESG----------GSEEPGGIGVGEKDWTSDVNVK 1234
G S + + G SG GS +G GE + +
Sbjct: 1531 SHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQ 1590
Query: 1235 SKDLAEVGEGGGHSQARE 1252
+++ + GHS+ E
Sbjct: 1591 GSSVSQDRDSEGHSEDSE 1608
Score = 39.7 bits (91), Expect = 0.026
Identities = 218/1034 (21%), Positives = 327/1034 (31%), Gaps = 192/1034 (18%)
Query: 635 ADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPP 694
A+ GQA E+A + A ++ D R S G SS+ + D +
Sbjct: 2307 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSA--VRD--SGHRG 2362
Query: 695 SGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEF-----GITGDPQPSSFSPSSWC 749
S G + +D+ + S + G G Q+ Q G +G + S+
Sbjct: 2363 SSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHE 2422
Query: 750 QGASQDYGLGGASPRGDPGL-------GERDWTSKYGQGAGEGSTREWAS-RCGIGQEEM 801
Q S +G G S G G R TS+ GQ G + R G E++
Sbjct: 2423 QSESA-HGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQL 2481
Query: 802 EASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTY--SSRD 859
S S S D G R D Q + + + SSR
Sbjct: 2482 VDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRA 2541
Query: 860 AELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQDANEQGQD--------LGK 911
+ G+ S G +SR+ W G+ SQD++ QG
Sbjct: 2542 DSSGHSQVGQGQSEGPRTSRN-----W--------GSSFSQDSDSQGHSEDSERWSGSAS 2588
Query: 912 RDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIR--DYSSGGSSRT 969
R+HHG Q D ++ RA + + + R SSGG + +
Sbjct: 2589 RNHHGSAQEQLRDGSRHPRSHQE-------DRAGHGHSADSSRQSGTRHTQTSSGGQAAS 2641
Query: 970 LDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPGERGSGGLFS 1029
Q RS S+G QQ + + RD+G G GS S
Sbjct: 2642 SHEQARS------SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQA--S 2693
Query: 1030 PSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGEMGKRGWVGE 1089
+ H D S Q+ A + G HQ+ Q A+G GE G G
Sbjct: 2694 DNEGHSED--------SDTQSVSAHGQAGSHQQSHQESARG------RSGETS--GHSGS 2737
Query: 1090 FSLSVGPQREAAFSPG-------QQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPSSK 1142
F V ++ S G + SR + S R + G D + G S
Sbjct: 2738 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR-HSASQDGQDTIRGHPGSSRGG 2796
Query: 1143 MEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSLRD 1202
+G H SVD + G + S S G S+A G S +
Sbjct: 2797 RQGYHH-------EHSVDSSGHSGSHH----SHTTSQGRSDASRGQSGSRSASRTTRNEE 2845
Query: 1203 MNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTD--- 1259
+ G SG E +D++ S+ + EG S+ + S V Q
Sbjct: 2846 QSGDGSRHSGSRHH-------EASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE 2898
Query: 1260 --------WSGV-------EAGEFLKSRER----------GVG-QADWTPDLGLRN---M 1290
WSG A E L+ R G G AD + G R+
Sbjct: 2899 GHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTS 2958
Query: 1291 APGAVCSPGESKELGVGQ---------MDWGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQ 1341
+ G S E G+ D + G+ + + G +G G
Sbjct: 2959 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 3018
Query: 1342 MD-WTQDLAPQNVELFG-APSEAREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEAREL 1399
+ ++D Q+V G A S + H + E H+GS + + E+
Sbjct: 3019 NEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETS-GHSGSFLYQVSTHEQSESSH- 3076
Query: 1400 GVGETSGPETQG-----------------EDYSSSSLEPHP---------------ADPG 1427
+GP T+G Y ++ HP D
Sbjct: 3077 ---GWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSS 3133
Query: 1428 METGEALSFGASPGRCPARPPPSGSQGLL-----EEMLAASSSKAVARRESAASGLGGLL 1482
+G S S GR A SGS+ EE SS +V+R A++ +
Sbjct: 3134 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTH-ADIS 3192
Query: 1483 EEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSR 1542
A G ++ + S S +G + +E W SA+R + SR
Sbjct: 3193 RHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSE----RWSGSASRNHRGSVQEQSR 3248
Query: 1543 RPSQGPPARSPSQD 1556
S+ P RS +D
Sbjct: 3249 HGSRHP--RSHHED 3260
Score = 38.9 bits (89), Expect = 0.044
Identities = 190/931 (20%), Positives = 287/931 (30%), Gaps = 157/931 (16%)
Query: 191 HDGSSRYGPRTYGTTTAPRDEDGST----LFRGWSQEGPVKSPAECREEHSKTPEERSLP 246
H GS + G + A R + GS R Q G + R + T + S
Sbjct: 3135 HSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRH 3194
Query: 247 SDLAFNGDLAKAASSELPADISKPWIPSSPAPSSEN-GGPASP---GLPAEASGSGPGSP 302
S S + +S+ + SE G AS G E S G P
Sbjct: 3195 SQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHP 3254
Query: 303 HLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAP 362
H D++ HS + Q+ A T S AA E +R +P
Sbjct: 3255 RSHHEDRAGHGHS------ADRSRQSGTRHAETSSGGQAASSHEQARSSPG--------- 3299
Query: 363 EAPRPSSPPPEVLEPH-SLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPT 421
E H S Q A S R P G A D+ +
Sbjct: 3300 -------------ERHGSRHQQSADSSRH-----------SGIPRGQASSAVRDSRHWGS 3335
Query: 422 SLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQ-LALDRPFGAESNWSLSQSFEWTF 480
S Q SEG S D + + G A P Q Q A DR G S SF +
Sbjct: 3336 SGSQASDSEG--HSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGR---SGSFLYQV 3390
Query: 481 PTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGS 540
T S T S A S SQ+GQ GS
Sbjct: 3391 STHEQ--------SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR 3442
Query: 541 SWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQE 600
QG S+ + G S T++G Q+ R S++ ++
Sbjct: 3443 RGRQGSHYEQSVDRSGHSGSHHSHT--------TSQGRSDASRGQSGSRSASRQTRNDEQ 3494
Query: 601 SPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQ 660
S G + AD+ Q+ + R Q
Sbjct: 3495 SGD----------------GSRHSWSHHHEASTQADSSRHSQSGQGQSAG---PRTSRNQ 3535
Query: 661 ARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQS----PSTC 716
+ +QD S E S RW SG +R G+ + ++ P++
Sbjct: 3536 GSSVSQD----SDSQGHSEDSERW----------SGSASRNHRGSAQEQSRDGSRHPTSH 3581
Query: 717 SEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPR-GDPGLGERDWT 775
E G S T + SS ++ +S + A R G D +
Sbjct: 3582 HEDRAGHGHSAESSRQSGTHHAENSSGGQAA----SSHEQARSSAGERHGSHHQQSADSS 3637
Query: 776 SKYGQGAGEGST--REWASRCGIGQEEMEA---SSSQDQSKVSAPGVL---------TAQ 821
G G G+ S+ R+ R G + ++ S D VSA G + +
Sbjct: 3638 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTR 3697
Query: 822 DRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDV 881
R G+ + G+ Q + + E + + R +Q + +D
Sbjct: 3698 GRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDT 3757
Query: 882 SLGDWEFGKRDSLGAYASQDANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYG 941
G + G+Y Q + G HH +SQ + D S G G
Sbjct: 3758 IRGHPGSRRGGRQGSYHEQSVDRSGHS---GSHHSHTTSQG---------RSDASHGQSG 3805
Query: 942 SRAA------EPQEQEFGKSAWIRDYSSG----GSSRTLDAQDRSFGTRPL----SSGFS 987
SR+A E Q + + + R + + S + Q S G+R SS
Sbjct: 3806 SRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQ 3865
Query: 988 PEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPGERGSGGLFSPSTAHVPDGALGQRDQSS 1047
+++ E+ E++ S + SR+ R G R G + +HV + Q D S+
Sbjct: 3866 DSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPV-QSDSST 3924
Query: 1048 WQN----SDASQEVGGHQERQQAGAQGPGSA 1074
+ S SQ+ H Q G+ S+
Sbjct: 3925 AKEHGHFSSLSQDSAYHSGIQSRGSPHSSSS 3955
Score = 36.6 bits (83), Expect = 0.22
Identities = 139/641 (21%), Positives = 212/641 (33%), Gaps = 81/641 (12%)
Query: 680 SSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQ 739
S+S++ D + P S G R+G E S + S SQ + G +G
Sbjct: 3101 SASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRS 3160
Query: 740 PSSFSPSSWCQGASQDYGLGG---ASPRGDPGLGERDWTSKYGQGAGEGSTREWASRCGI 796
S + + G S + + AS D S+ QG EGS R +
Sbjct: 3161 ASRTTRNEEQSGDSSRHSVSRHHEASTHADISRH-----SQAVQGQSEGSRRSRRQGSSV 3215
Query: 797 GQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTYS 856
Q+ S+D + S + V Q ++ E R
Sbjct: 3216 SQDSDSEGHSEDSERWSGSASRNHRGSV-----QEQSRHGSRHPRSHHEDRAGHGHSADR 3270
Query: 857 SRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQDAN-EQGQ-DLGKRD- 913
SR + + E + + S G R A +S+ + +GQ RD
Sbjct: 3271 SRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDS 3330
Query: 914 -HHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRDYSSGGSSR---- 968
H G SQ +D + + S+ +G A P +Q +SA RD S G S R
Sbjct: 3331 RHWGSSGSQASDSEGHSEESDTQSVSGHGQ--AGPHQQSHQESA--RDRSGGRSGRSGSF 3386
Query: 969 -----TLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDA--GRPG- 1020
T + + + G S+G ++Q E+ S S + +D G PG
Sbjct: 3387 LYQVSTHEQSESAHGRTRTSTG------RRQGSHHEQARDSSRHSASQEGQDTIRGHPGS 3440
Query: 1021 -ERG-SGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLED 1078
RG G + S +S SDAS+ G + A Q D
Sbjct: 3441 SRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASR---GQSGSRSASRQTRNDEQSGD 3497
Query: 1079 GEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIG----NDRVSG 1134
G E S R + GQ R + S S G ++R SG
Sbjct: 3498 GSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 3557
Query: 1135 A------GFSPSSKMEGG-HFVPPGKTTAG---SVDWTDQLGLRNLEVSSCVGSGGSSEA 1184
+ G + +G H + AG S + + Q G + E SS + S E
Sbjct: 3558 SASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQ 3617
Query: 1185 RESAVGQ---------------MGWSGGLSLRDMNLTGCLESGGSEEPGGIGVGEKDWTS 1229
S+ G+ G G + + +G S GS+ G E T
Sbjct: 3618 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQ 3677
Query: 1230 DVNVKSKDLAEVGEGGGHSQA-RESGVGQTDWSGVEAGEFL 1269
V+ G+ G H Q+ +ES G++ +G FL
Sbjct: 3678 SVSAH-------GQAGPHQQSHQESTRGRSAGRSGRSGSFL 3711
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 62.4 bits (150), Expect = 4e-09
Identities = 101/410 (24%), Positives = 139/410 (33%), Gaps = 46/410 (11%)
Query: 8 ESSAMASPLPREMEEELVPTGSEPGDTRAKP--PVKPKPRALPAKPALPAKPSLLVPVGP 65
+SSA L + PTG P + A P P P P P+ A+P + S P
Sbjct: 172 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP 231
Query: 66 RPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPF-APRPAVEASTGGEATQETGKEEAGK 124
P+ P A +P A S P P +P P ++ TG G+ A
Sbjct: 232 NQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTG-----SAGQPSAPS 286
Query: 125 EEPPPL----TPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD 180
PPL P G + + P P +P A+ + L P +
Sbjct: 287 HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG--TSPAAAYPHTSL 344
Query: 181 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPV-KSPAECREEHSKT 239
+L S+ R P P + T P+ + PA +H
Sbjct: 345 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT--------PIPQLPAPQAHKH--- 393
Query: 240 PEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAP-----SSENGGPASPGLPAEA 294
P S PS + N +L + + + +S PS+ P P+SP P
Sbjct: 394 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL 453
Query: 295 SGSG--PGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEG---SR 349
+ S P P HPP Q AQ P P P P+ PS + P G S
Sbjct: 454 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV-PGGPPPITPPTCPSTSTPPAGPGTSA 512
Query: 350 HTPSPGLPAEGAPEAPRPSSPPPEV-LEPHSLDQ--------PPATSPRP 390
P G A G A S P P V ++ +LD PP SP P
Sbjct: 513 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 562
Score = 53.9 bits (128), Expect = 1e-06
Identities = 133/579 (22%), Positives = 188/579 (32%), Gaps = 120/579 (20%)
Query: 165 LAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQ-- 222
++ + RK+ ASPD G N D S +T+ D T+ + +
Sbjct: 27 MSTLRSGRKKQPASPD---GRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVK 83
Query: 223 ---EGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPS 279
P+KS RE+ + EE S K P S+ SS + S
Sbjct: 84 EEASSPLKSNKRQREKVASDTEEADRTSSKK-----TKTQEISRPNSPSEGEGESSDSRS 138
Query: 280 SENGGPASP-GLPAEASGSGPG--SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTP 336
+ G + P + + + P SP + D S Q+L+AQ P A P
Sbjct: 139 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP----ALQAPTGVT 194
Query: 337 SAPSAALPDEGSRHTPSP-----GLPAEGAPEAPR-------PSSPPPEV---------- 374
APS+A P TP P +P +G+P A + P++P P
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 254
Query: 375 LEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSE---- 430
P S PP SP P ++ + PS + G P SL +
Sbjct: 255 QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 314
Query: 431 ----GVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSG 486
G+ SQ Q LG S AA QL A + SQ P P+
Sbjct: 315 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP------ASQSALQSQQPPREQPLPPAP 368
Query: 487 LGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGD 546
L + + PP +PI + +L+ G S A P
Sbjct: 369 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLS------GPSPFSMNANLPP----------- 411
Query: 547 DPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLA 606
P++ P PL+ +P ++ P P +Q P Q LP
Sbjct: 412 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP---------AQPPGLTQSQNLP-- 460
Query: 607 TREAALPILEPVLGQEQPAAPDQPCVLFADAP-EPGQALPVEEEAVTLARAETTQARTEA 665
P P G Q AP P FA P PG P+
Sbjct: 461 ----PPPASHPPTGLHQ-VAPQPP---FAQHPFVPGGPPPI------------------T 494
Query: 666 QDLCRASPEPP-GPESSSRWLDDLLASPPPSGGGARRGA 703
C ++ PP GP +S A PP SG A G+
Sbjct: 495 PPTCPSTSTPPAGPGTS--------AQPPCSGAAASGGS 525
Score = 45.8 bits (107), Expect = 4e-04
Identities = 81/321 (25%), Positives = 105/321 (32%), Gaps = 62/321 (19%)
Query: 278 PSSENGGPASP-GLPAEAS------GSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASP 330
P ++ GP P GLP +AS G+ P + + H + S L Q P P
Sbjct: 307 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366
Query: 331 CPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRP 390
P P TP P LPA A + P S P +L PPA P
Sbjct: 367 APLAMPHIKPPPT-------TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP-- 417
Query: 391 LIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQ-----DQEKLGG 445
L L+ P AH P L+ + S+ + SP+Q + L
Sbjct: 418 ------LSSLSTHHPP--------SAHPPPLQLMPQ--SQPLPSSPAQPPGLTQSQNLPP 461
Query: 446 SLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASE 505
A+ P Q+A PF P P G PP +P T S
Sbjct: 462 PPASHPPTGLHQVAPQPPFAQH-------------PFVPGG-------PPPITPPTCPST 501
Query: 506 AAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFP 565
+ A G +S + S GS GS +L + ES P P
Sbjct: 502 STPPAGPG----TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 557
Query: 566 AVPLEPLPTTEGTPGLPLQQA 586
P P PT TP Q A
Sbjct: 558 RSP-SPEPTVVDTPSHASQSA 577
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 62.4 bits (150), Expect = 4e-09
Identities = 101/410 (24%), Positives = 139/410 (33%), Gaps = 46/410 (11%)
Query: 8 ESSAMASPLPREMEEELVPTGSEPGDTRAKP--PVKPKPRALPAKPALPAKPSLLVPVGP 65
+SSA L + PTG P + A P P P P P+ A+P + S P
Sbjct: 726 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP 785
Query: 66 RPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPF-APRPAVEASTGGEATQETGKEEAGK 124
P+ P A +P A S P P +P P ++ TG G+ A
Sbjct: 786 NQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTG-----SAGQPSAPS 840
Query: 125 EEPPPL----TPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD 180
PPL P G + + P P +P A+ + L P +
Sbjct: 841 HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG--TSPAAAYPHTSL 898
Query: 181 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPV-KSPAECREEHSKT 239
+L S+ R P P + T P+ + PA +H
Sbjct: 899 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT--------PIPQLPAPQAHKH--- 947
Query: 240 PEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAP-----SSENGGPASPGLPAEA 294
P S PS + N +L + + + +S PS+ P P+SP P
Sbjct: 948 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL 1007
Query: 295 SGSG--PGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEG---SR 349
+ S P P HPP Q AQ P P P P+ PS + P G S
Sbjct: 1008 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV-PGGPPPITPPTCPSTSTPPAGPGTSA 1066
Query: 350 HTPSPGLPAEGAPEAPRPSSPPPEV-LEPHSLDQ--------PPATSPRP 390
P G A G A S P P V ++ +LD PP SP P
Sbjct: 1067 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 1116
Score = 53.9 bits (128), Expect = 1e-06
Identities = 133/579 (22%), Positives = 188/579 (32%), Gaps = 120/579 (20%)
Query: 165 LAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQ-- 222
++ + RK+ ASPD G N D S +T+ D T+ + +
Sbjct: 581 MSTLRSGRKKQPASPD---GRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVK 637
Query: 223 ---EGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPS 279
P+KS RE+ + EE S K P S+ SS + S
Sbjct: 638 EEASSPLKSNKRQREKVASDTEEADRTSSKK-----TKTQEISRPNSPSEGEGESSDSRS 692
Query: 280 SENGGPASP-GLPAEASGSGPG--SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTP 336
+ G + P + + + P SP + D S Q+L+AQ P A P
Sbjct: 693 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP----ALQAPTGVT 748
Query: 337 SAPSAALPDEGSRHTPSP-----GLPAEGAPEAPR-------PSSPPPEV---------- 374
APS+A P TP P +P +G+P A + P++P P
Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 808
Query: 375 LEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSE---- 430
P S PP SP P ++ + PS + G P SL +
Sbjct: 809 QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 868
Query: 431 ----GVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSG 486
G+ SQ Q LG S AA QL A + SQ P P+
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP------ASQSALQSQQPPREQPLPPAP 922
Query: 487 LGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGD 546
L + + PP +PI + +L+ G S A P
Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLS------GPSPFSMNANLPP----------- 965
Query: 547 DPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLA 606
P++ P PL+ +P ++ P P +Q P Q LP
Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP---------AQPPGLTQSQNLP-- 1014
Query: 607 TREAALPILEPVLGQEQPAAPDQPCVLFADAP-EPGQALPVEEEAVTLARAETTQARTEA 665
P P G Q AP P FA P PG P+
Sbjct: 1015 ----PPPASHPPTGLHQ-VAPQPP---FAQHPFVPGGPPPI------------------T 1048
Query: 666 QDLCRASPEPP-GPESSSRWLDDLLASPPPSGGGARRGA 703
C ++ PP GP +S A PP SG A G+
Sbjct: 1049 PPTCPSTSTPPAGPGTS--------AQPPCSGAAASGGS 1079
Score = 45.8 bits (107), Expect = 4e-04
Identities = 81/321 (25%), Positives = 105/321 (32%), Gaps = 62/321 (19%)
Query: 278 PSSENGGPASP-GLPAEAS------GSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASP 330
P ++ GP P GLP +AS G+ P + + H + S L Q P P
Sbjct: 861 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920
Query: 331 CPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRP 390
P P TP P LPA A + P S P +L PPA P
Sbjct: 921 APLAMPHIKPPPT-------TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP-- 971
Query: 391 LIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQ-----DQEKLGG 445
L L+ P AH P L+ + S+ + SP+Q + L
Sbjct: 972 ------LSSLSTHHPP--------SAHPPPLQLMPQ--SQPLPSSPAQPPGLTQSQNLPP 1015
Query: 446 SLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASE 505
A+ P Q+A PF P P G PP +P T S
Sbjct: 1016 PPASHPPTGLHQVAPQPPFAQH-------------PFVPGG-------PPPITPPTCPST 1055
Query: 506 AAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFP 565
+ A G +S + S GS GS +L + ES P P
Sbjct: 1056 STPPAGPG----TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111
Query: 566 AVPLEPLPTTEGTPGLPLQQA 586
P P PT TP Q A
Sbjct: 1112 RSP-SPEPTVVDTPSHASQSA 1131
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 62.4 bits (150), Expect = 4e-09
Identities = 101/410 (24%), Positives = 139/410 (33%), Gaps = 46/410 (11%)
Query: 8 ESSAMASPLPREMEEELVPTGSEPGDTRAKP--PVKPKPRALPAKPALPAKPSLLVPVGP 65
+SSA L + PTG P + A P P P P P+ A+P + S P
Sbjct: 726 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP 785
Query: 66 RPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPF-APRPAVEASTGGEATQETGKEEAGK 124
P+ P A +P A S P P +P P ++ TG G+ A
Sbjct: 786 NQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTG-----SAGQPSAPS 840
Query: 125 EEPPPL----TPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPD 180
PPL P G + + P P +P A+ + L P +
Sbjct: 841 HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG--TSPAAAYPHTSL 898
Query: 181 RLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPV-KSPAECREEHSKT 239
+L S+ R P P + T P+ + PA +H
Sbjct: 899 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT--------PIPQLPAPQAHKH--- 947
Query: 240 PEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAP-----SSENGGPASPGLPAEA 294
P S PS + N +L + + + +S PS+ P P+SP P
Sbjct: 948 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL 1007
Query: 295 SGSG--PGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEG---SR 349
+ S P P HPP Q AQ P P P P+ PS + P G S
Sbjct: 1008 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV-PGGPPPITPPTCPSTSTPPAGPGTSA 1066
Query: 350 HTPSPGLPAEGAPEAPRPSSPPPEV-LEPHSLDQ--------PPATSPRP 390
P G A G A S P P V ++ +LD PP SP P
Sbjct: 1067 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 1116
Score = 53.9 bits (128), Expect = 1e-06
Identities = 133/579 (22%), Positives = 188/579 (32%), Gaps = 120/579 (20%)
Query: 165 LAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQ-- 222
++ + RK+ ASPD G N D S +T+ D T+ + +
Sbjct: 581 MSTLRSGRKKQPASPD---GRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVK 637
Query: 223 ---EGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPS 279
P+KS RE+ + EE S K P S+ SS + S
Sbjct: 638 EEASSPLKSNKRQREKVASDTEEADRTSSKK-----TKTQEISRPNSPSEGEGESSDSRS 692
Query: 280 SENGGPASP-GLPAEASGSGPG--SPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTP 336
+ G + P + + + P SP + D S Q+L+AQ P A P
Sbjct: 693 VNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP----ALQAPTGVT 748
Query: 337 SAPSAALPDEGSRHTPSP-----GLPAEGAPEAPR-------PSSPPPEV---------- 374
APS+A P TP P +P +G+P A + P++P P
Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 808
Query: 375 LEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSE---- 430
P S PP SP P ++ + PS + G P SL +
Sbjct: 809 QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 868
Query: 431 ----GVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSG 486
G+ SQ Q LG S AA QL A + SQ P P+
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP------ASQSALQSQQPPREQPLPPAP 922
Query: 487 LGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGD 546
L + + PP +PI + +L+ G S A P
Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLS------GPSPFSMNANLPP----------- 965
Query: 547 DPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLA 606
P++ P PL+ +P ++ P P +Q P Q LP
Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP---------AQPPGLTQSQNLP-- 1014
Query: 607 TREAALPILEPVLGQEQPAAPDQPCVLFADAP-EPGQALPVEEEAVTLARAETTQARTEA 665
P P G Q AP P FA P PG P+
Sbjct: 1015 ----PPPASHPPTGLHQ-VAPQPP---FAQHPFVPGGPPPI------------------T 1048
Query: 666 QDLCRASPEPP-GPESSSRWLDDLLASPPPSGGGARRGA 703
C ++ PP GP +S A PP SG A G+
Sbjct: 1049 PPTCPSTSTPPAGPGTS--------AQPPCSGAAASGGS 1079
Score = 45.8 bits (107), Expect = 4e-04
Identities = 81/321 (25%), Positives = 105/321 (32%), Gaps = 62/321 (19%)
Query: 278 PSSENGGPASP-GLPAEAS------GSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASP 330
P ++ GP P GLP +AS G+ P + + H + S L Q P P
Sbjct: 861 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920
Query: 331 CPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRP 390
P P TP P LPA A + P S P +L PPA P
Sbjct: 921 APLAMPHIKPPPT-------TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP-- 971
Query: 391 LIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQ-----DQEKLGG 445
L L+ P AH P L+ + S+ + SP+Q + L
Sbjct: 972 ------LSSLSTHHPP--------SAHPPPLQLMPQ--SQPLPSSPAQPPGLTQSQNLPP 1015
Query: 446 SLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASE 505
A+ P Q+A PF P P G PP +P T S
Sbjct: 1016 PPASHPPTGLHQVAPQPPFAQH-------------PFVPGG-------PPPITPPTCPST 1055
Query: 506 AAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFP 565
+ A G +S + S GS GS +L + ES P P
Sbjct: 1056 STPPAGPG----TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111
Query: 566 AVPLEPLPTTEGTPGLPLQQA 586
P P PT TP Q A
Sbjct: 1112 RSP-SPEPTVVDTPSHASQSA 1131
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 62.0 bits (149), Expect = 5e-09
Identities = 209/976 (21%), Positives = 317/976 (32%), Gaps = 170/976 (17%)
Query: 4 STLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPV 63
+T E + SPL + +E+ + G PPV P P L + P P +
Sbjct: 798 ATPAEPRPLTSPLRQAADED------DKGMRSETPPVPPPPPYLASYPGFPENGA----P 847
Query: 64 GPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEAS--TGGEATQETGK-E 120
GP R PL E P R + G + P P P E + TG EA ++ +
Sbjct: 848 GPPISRFPLEE-PGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGV 906
Query: 121 EAGKEEPPPLTPPARCAA-----PGGVRKAPAPFRPASERFAA---------TTVEEILA 166
+G + PPP +R PG R+ P P + A T VEE+
Sbjct: 907 GSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPP 966
Query: 167 KMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQE--G 224
K + E P + ++T G + P + APR L R +S E G
Sbjct: 967 KPLEQGDET-PKPPKPDPLKITKGKLGGPKETPPNGNLSPAPR------LRRDYSYERVG 1019
Query: 225 PVKSPAECREEH--------------SKTPEERSLPSDLAFNGDLAKAASSELPADISKP 270
P R E+ + R S F GD + + P P
Sbjct: 1020 PTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAP 1079
Query: 271 WIPSSPAPSSENGG----PASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEAS 326
++ SE P +GS L P DK +P + Q P
Sbjct: 1080 RGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVP--- 1136
Query: 327 QASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPS-------SPPPEVL---E 376
A P P PS A G R G+P+ RP SPP + L +
Sbjct: 1137 LAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKK 1196
Query: 377 PHSLDQPPATSP-RPLIEVGELLDLTRTFPSGGEEEAKGDA------------------- 416
P + PP+ P + + G L + R +GG D
Sbjct: 1197 PPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPR 1256
Query: 417 --HLRPTSLVQRRFSEG------VLQSPSQDQEKLGGSLAALPQ---GQGSQLALDRPFG 465
L+ R SEG +P ++ ++A P+ + L+
Sbjct: 1257 FRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQ 1316
Query: 466 AESNW-SLSQSFEWTFPTR------------------PSGLGVWRLDSPPPSPITEASEA 506
A W + S+S ++T R P G G + P S ++ +
Sbjct: 1317 ANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAV--PGISAMSRGDLS 1374
Query: 507 AEAAEAGNLAVSSREEGVSQQGQ--GAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQF 564
A + + SS+ G+ +Q + G G SGSS G T G G+ + +
Sbjct: 1375 QRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKR-SW 1433
Query: 565 PAVPLEPLPTTEGTPGLPLQQAE---------ERYESQEPLAGQESPLPLATREAAL--P 613
P+ P E PGLPL ++ P Q++ L++R+ ++ P
Sbjct: 1434 PSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP 1493
Query: 614 ILEPVLGQEQPAAPDQPCVLFADAPEPGQ------ALPVEEEAVTLARAETTQARTEAQD 667
P P AP P EP + + P EE + R R D
Sbjct: 1494 GGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPR----D 1549
Query: 668 LCRASPEPP----GPESSSRWLDDLLASPPPSGG--GAR---RGAGAELKDT----QSPS 714
SP PP P L + PP S G G++ G AE +DT +P
Sbjct: 1550 SAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPH 1609
Query: 715 TCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDW 774
+ S+K + + +P SP G G GD +
Sbjct: 1610 IWNRLHTATSRKSYRPS---SMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPC 1666
Query: 775 TSKYG-----QGAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGK-- 827
+ + +GA EG + + E + + P + + +
Sbjct: 1667 SQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQ 1726
Query: 828 ---PAQLGTQRSQEAD 840
P +GT+RSQ D
Sbjct: 1727 PLPPGPIGTERSQRTD 1742
Score = 58.9 bits (141), Expect = 4e-08
Identities = 182/777 (23%), Positives = 252/777 (32%), Gaps = 143/777 (18%)
Query: 28 GSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPP-RGPLAELPSARKMNMLAG 86
G +P PP + P LP P P GP+ P R P + PS + +AG
Sbjct: 234 GLQPSGPPQFPPYRGMMPPFMYPPYLPFPP----PYGPQGPYRYPTPDGPS--RFPRVAG 287
Query: 87 PQPYGGSKRPLPFAPRPAV--------------EASTG---------------------G 111
P+ G R + RP++ E G G
Sbjct: 288 PRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDG 347
Query: 112 EATQETGKE------EAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL 165
+ E G E A EE PP + +P + P P +E E
Sbjct: 348 RDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNS--EPPTPKTAWAETSRPPETEPGP 405
Query: 166 AKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGP 225
+ P P WG + G P AP DED + R
Sbjct: 406 PAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKP------PAPEDEDEAWRQRRKQSSSE 459
Query: 226 VKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSE----LPADISKPWIPSSPAPSSE 281
+ E R + EER + + +AA +E L P P++
Sbjct: 460 ISLAVE-RARRRREEEERRMQEE-------RRAACAEKLKRLDEKFGAPDKRLKAEPAAP 511
Query: 282 NGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSA 341
P++P P P P PP S+P E + E +QA P + TP+ A
Sbjct: 512 PAAPSTPAPPPAVPKELPAPPA--PPPASAPTP----ETEPEEPAQAPPAQS-TPTPGVA 564
Query: 342 ALP----DEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIE-VGE 396
A P GS + S G E +P P P E EP PP T P P +E G+
Sbjct: 565 AAPTLVSGGGSTSSTSSG-SFEASP--VEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGD 621
Query: 397 LLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGS 456
+ TR PS G K L P QR+ E +L+ Q Q + QGS
Sbjct: 622 GIGPTRQPPSQGLGYPKYQKSLPPR--FQRQQQEQLLKQQQQHQWQ--------QHQQGS 671
Query: 457 QLALDRPFGAESNWSL-SQSFEWTFPTRPSGLGVWRLDSPPPSP--------ITEASEAA 507
P +L + P P L L PPP P +
Sbjct: 672 APPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVD 731
Query: 508 EAAEAGNLAVSSREEGVSQQG--QGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQ-- 563
G + GV G S GS S P+M L ++G P+
Sbjct: 732 PRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAM-LRERGTPPVDPKLA 790
Query: 564 -----FPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPV 618
F A P EP P T PL+QA + E + + + P+P P L
Sbjct: 791 WVGDVFTATPAEPRPLTS-----PLRQAAD--EDDKGMRSETPPVP-----PPPPYLASY 838
Query: 619 LGQEQPAAPDQPCVLFADAPEPG-QALPVEEEAVTLARAETTQARTEAQDLCRASPEPPG 677
G + AP P F EPG + LP + +A+ +T + EPP
Sbjct: 839 PGFPENGAPGPPISRF-PLEEPGPRPLPWPPGSDEVAKIQTPPPK----------KEPPK 887
Query: 678 PESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGI 734
E++ + P +G RG G+ + P S W + S GI
Sbjct: 888 EETAQ-------LTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGI 937
Score = 56.2 bits (134), Expect = 3e-07
Identities = 205/923 (22%), Positives = 287/923 (31%), Gaps = 201/923 (21%)
Query: 7 RESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPR 66
R + + P P EEL P E GD KPP KP P + K L GP+
Sbjct: 947 RRAGPIKKPPPPTKVEELPPKPLEQGDETPKPP-KPDPLKI-------TKGKL---GGPK 995
Query: 67 --PPRGPLAELPSARK--MNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEA 122
PP G L+ P R+ GP G R FA + GG +E
Sbjct: 996 ETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFR 1055
Query: 123 GKEEPPPLTPPARCAAPGGVRKAPAP-FRPASERFAATTVEEILAKMEQPRKEVLASPDR 181
E R GG PAP R ASE + + E + K + R
Sbjct: 1056 SYRE--FRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQR--------- 1104
Query: 182 LWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPV----------KSPAE 231
S G T+ + AP D++ T G + P+ +PA
Sbjct: 1105 ------------GSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPAR 1152
Query: 232 CREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIP--SSPAPSSENGGPASPG 289
+ R +PS G P + W P S AP GP P
Sbjct: 1153 FTARGGRVFTPRGVPSRRGRGG-------GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPS 1205
Query: 290 -------------LPAEASGSGPGS-------------PHLHPPDKSSPCHSQLLEAQTP 323
P GS GS H + P + L+ +
Sbjct: 1206 KEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERE 1265
Query: 324 EA---SQASPCPAVTPSAPS--------AALPDEGSRHTPSPGLPAEGAPEAPRPSSPPP 372
A S+ P + SAP P SP L + + +A
Sbjct: 1266 NAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETAS 1325
Query: 373 EVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGG--------EEEAKGDAHLRPTSLV 424
E + S + +P P++ + + P GG ++GD R L
Sbjct: 1326 ESSDFTSERRGDKEAPPPVLLTPKAVGT----PGGGGGGAVPGISAMSRGDLSQRAKDLS 1381
Query: 425 QRRFSEGVLQSPSQDQE--------KLGGSLAALPQGQGSQLALDRP-FGAESNWSLSQS 475
+R FS Q P +++ K G S ++ G G P G + +W ++
Sbjct: 1382 KRSFSS---QRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKN 1438
Query: 476 FEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLA--------VSSREEGVSQQ 527
RP GL + PPP P + A + N A +SSR+ V+
Sbjct: 1439 RSRPPEERPPGLPL-----PPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP 1493
Query: 528 G------QGAGSAPSGSGSSWVQGDDPSMSLTQKGDG--ESQPQFPAVPLEPLPTTEGTP 579
G G AP G P+ Q+ + S P F EP P G
Sbjct: 1494 GGHPRHKPGLPQAPQGPSPR-----PPTRYEPQRVNSGLSSDPHFE----EPGPMVRGVG 1544
Query: 580 GLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPE 639
G P A SP P RE P +P L QE+ P PE
Sbjct: 1545 GTPRDSA------------GVSPFPPKRRER--PPRKPELLQEESLPPPHSSGFLGSKPE 1590
Query: 640 -PGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGG 698
PG P E T A T S + P S W++ L SP
Sbjct: 1591 GPG---PQAESRDTGTEALTPHIWNRLH--TATSRKSYRPSSMEPWMEPL--SP------ 1637
Query: 699 ARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQ--DY 756
AG E+ + S DL + ++ P SP +GA++
Sbjct: 1638 FEDVAGTEMSQSD------------SGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPK 1685
Query: 757 GLGGASP------RGDPGLGERDWTSKYGQGAGEGSTREWASRCGIGQEEMEASSSQDQS 810
GG+SP G PG + + +G +E + + SQ
Sbjct: 1686 RPGGSSPLNAVPCEGPPG---SEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTD 1742
Query: 811 KVSAPGVLTAQDRVVGKPAQLGT 833
+ + PG + R G P Q GT
Sbjct: 1743 RGTEPGPIRPSHR-PGPPVQFGT 1764
Score = 46.2 bits (108), Expect = 3e-04
Identities = 145/638 (22%), Positives = 212/638 (33%), Gaps = 106/638 (16%)
Query: 4 STLRESSAMASPLPREMEEELVPTGSE---PGDTRAKPPVKPKPRALPAKPALPAK---- 56
S+ S ASP+ ++ + P E P T P V+PK + P++
Sbjct: 577 SSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGY 636
Query: 57 PSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQE 116
P + PR R +L ++ + Q GS P P P P + G +
Sbjct: 637 PKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQ--GSAPPTPVPPSPPQPVTLGAVPAPQ 694
Query: 117 TGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEIL-AKMEQPRKEV 175
PP PP + PG + + P P P + + + ++ Q R +
Sbjct: 695 A----------PP--PPPKALYPGALGRPP-PMPPMNFDPRWMMIPPYVDPRLLQGRPPL 741
Query: 176 LASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREE 235
P + S L S G+++ P D + R A +
Sbjct: 742 DFYPPGVHPSGLVPRERSDSG------GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDV 795
Query: 236 HSKTPEE-RSLPSDL--AFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASP--GL 290
+ TP E R L S L A + D S P P++ S P ENG P P
Sbjct: 796 FTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG-FPENGAPGPPISRF 854
Query: 291 PAEASGSGP-----GSPHLH----PPDKSSPCHSQLLEAQTPEAS-----------QASP 330
P E G P GS + PP K P + + PEA Q P
Sbjct: 855 PLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPP 914
Query: 331 CPAVTPSAPSAALPDEGS--RHTP--SPGLPAEGAPEAPRPSSP------PPEVLEPHSL 380
P + P GS R P PG P A +P P PP+ LE
Sbjct: 915 PPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGD- 973
Query: 381 DQPPATSPRPL-IEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQD 439
+ P P PL I G+L GG +E + +L P ++R +S
Sbjct: 974 ETPKPPKPDPLKITKGKL---------GGPKETPPNGNLSPAPRLRRDYS---------- 1014
Query: 440 QEKLGGSLAALPQGQGSQLALDRPF----GAESNWSLSQSFEWTFPTRPSGLGVWRLDSP 495
E++G + + +G+G A R F G + S+ F R P
Sbjct: 1015 YERVGPT-SCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGP 1073
Query: 496 PPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQK 555
P A+E G S EE ++ Q S + S + D ++
Sbjct: 1074 NHPPAPRGRTASETRSEG----SEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKE 1129
Query: 556 GDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQ 593
G VPL P P PG P A R+ ++
Sbjct: 1130 G------TLTQVPLAPPP-----PGAPPSPAPARFTAR 1156
Score = 40.0 bits (92), Expect = 0.020
Identities = 117/555 (21%), Positives = 170/555 (30%), Gaps = 165/555 (29%)
Query: 28 GSEPGDTRAKPPVKPKPRALPA-KPALPAKPSLLVP-----VGPRPPR-GPLAELPSA-- 78
G P D+ P PK R P KP L + SL P +G +P GP AE
Sbjct: 1544 GGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGT 1603
Query: 79 --------RKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPL 130
+++ + Y S P E G E +Q + +
Sbjct: 1604 EALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSS 1663
Query: 131 TPPARCAAPGGVRKAPA---PFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRL 187
P ++ ++P G K A P RP E E PR+ A
Sbjct: 1664 GPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAP--------- 1714
Query: 188 TFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKS------PAECREEHSKTPE 241
HDG + PR P + S ++ GP++ P + +
Sbjct: 1715 ---HDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDL 1771
Query: 242 ERSLPSDLAFNGDLAKAASSELPADISKPW--IPSS-----------------PAPSSE- 281
+ L +L + + +P +S+ W +PS+ P PSS
Sbjct: 1772 RLVVGDSLKAEKELTASVTEAIP--VSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSG 1829
Query: 282 -------------------NGGPASPGLPAEASGSGPGSPHLH---------PPDKSSP- 312
+GG L + G PG+P LH PP + P
Sbjct: 1830 QRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPS 1889
Query: 313 -------CHSQLLEAQTPEASQASPCPA-----------VTPSAPSAALPD----EGSRH 350
Q L+ T +A++ PA +P+ + LPD + +
Sbjct: 1890 ALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQD 1949
Query: 351 TPSP-------------------GLPAE-----------------GAPEAPRPSSPPPEV 374
PSP G PA+ P AP P+ PP +
Sbjct: 1950 LPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSL 2009
Query: 375 LEPHSLDQPP--ATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGV 432
L QPP A P P L R FP+ + G A L P L
Sbjct: 2010 LPVGPALQPPSLAVRPPPAPATRVLPSPARPFPA-----SLGRAELHPVEL--------- 2055
Query: 433 LQSPSQDQEKLGGSL 447
P QD +KL +L
Sbjct: 2056 --KPFQDYQKLSSNL 2068
Score = 33.1 bits (74), Expect = 2.4
Identities = 45/183 (24%), Positives = 61/183 (33%), Gaps = 17/183 (9%)
Query: 1376 PGLRHNGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALS 1435
PG NG+ P + +R PLE G P G D + P P + A
Sbjct: 839 PGFPENGAPGPPI-SRFPLEEP----GPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQL 893
Query: 1436 FGASPGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEE 1495
G GR PAR SG QG RRES G + G EE
Sbjct: 894 TGPEAGRKPARGVGSGGQG-----------PPPPRRESRTETRWG-PRPGSSRRGIPPEE 941
Query: 1496 VLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQ 1555
P R + P +P P + + G + P + ++ GP P+
Sbjct: 942 PGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNG 1001
Query: 1556 DFS 1558
+ S
Sbjct: 1002 NLS 1004
Score = 31.6 bits (70), Expect = 7.0
Identities = 46/192 (23%), Positives = 67/192 (34%), Gaps = 29/192 (15%)
Query: 219 GWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAK---AASSELPADIS--KPWIP 273
GW+ + P ++ PE + LP+ + K AA P S K W
Sbjct: 85 GWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQ 144
Query: 274 SSPAPSSE-NGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCP 332
+S + +GG AS L + P DK++ E ++ E S + P P
Sbjct: 145 ASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAK------ERESAEQS-SGPGP 197
Query: 333 AVTPSAPSAALPDEGSR---------------HTPSPGLPAEGAPEAPRPSSPPPEVLEP 377
++ P S D G R H P GL G P+ P P + P
Sbjct: 198 SLRPQN-STTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYP 256
Query: 378 HSLDQPPATSPR 389
L PP P+
Sbjct: 257 PYLPFPPPYGPQ 268
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 62.0 bits (149), Expect = 5e-09
Identities = 148/642 (23%), Positives = 191/642 (29%), Gaps = 122/642 (19%)
Query: 38 PPVKPKPRALPAKPALPAKPSLLV-PVGPRPPRGPLAELPSARKMNMLAG-----PQPY- 90
PP P + P +P +P V P G P P P++R G PQ Y
Sbjct: 166 PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP----PTSRMFQAPPGAPPPHPQLYP 221
Query: 91 ---GGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPA 147
GG P P+ GG A G GK+ PPP TP + + G AP
Sbjct: 222 GGTGGVLSGPPMGPK-------GGGAASSVGGPNGGKQHPPPTTPIS--VSSSGASGAPP 272
Query: 148 -------------PFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGS 194
P P F T +P ASP L L +
Sbjct: 273 TKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSP 332
Query: 195 SRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGD 254
G G P ++GP +P+ HS P S P
Sbjct: 333 HAMGQGMGGLPPGP-------------EKGPTLAPSP----HSLPPASSSAP-------- 367
Query: 255 LAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCH 314
A P S SS A SS + +S P AS + P PH PP S
Sbjct: 368 ---APPMRFPYSSSSS---SSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVS 421
Query: 315 SQLLEAQTPEA-SQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRP------ 367
+Q + P SQA P P L + H P P P+ GA P
Sbjct: 422 NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAH-PGPFPPSTGAQSTAHPPVSTHH 480
Query: 368 --------------------------SSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLT 401
S PPP PH L+ + P L L
Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL- 539
Query: 402 RTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSP-------SQDQEKLGGSLAALPQGQ 454
R +P G AHL P Q +S+ P S G + P
Sbjct: 540 RPYPPG-------PAHLPPPHS-QVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS 591
Query: 455 GSQLALDRPFGAESNWSLSQS-FEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAG 513
PF + S + T S ++ SPP P + A + A
Sbjct: 592 QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP--PYGKRAPSPGAY 649
Query: 514 NLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDP-SMSLTQKGDGESQPQFPA-VPLEP 571
A + S G+ P G+S G G G P P+ +P P
Sbjct: 650 KTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709
Query: 572 LPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALP 613
P G PL + + E E ESP+P A + P
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Score = 47.0 bits (110), Expect = 2e-04
Identities = 79/365 (21%), Positives = 119/365 (32%), Gaps = 39/365 (10%)
Query: 15 PLPREMEEEL--VPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGPL 72
P P M + + +P G E G T A P P +LP + P + P
Sbjct: 330 PSPHAMGQGMGGLPPGPEKGPTLA-----PSPHSLPPASSSAPAPPMRFPYSSSSSSSAA 384
Query: 73 AELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETG----KEEAGKEEPP 128
A S+ + A P P + P + P S + + T + + PP
Sbjct: 385 ASSSSSSSSSS-ASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP 443
Query: 129 PLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLT 188
P P R A P PF P S +T + +++ + +
Sbjct: 444 PPPPYGRLLANSNAH--PGPF-PPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQ 500
Query: 189 FNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKS--PAECREEHSKTPEERSLP 246
H G+S GP G P + S ++ + S P H P +
Sbjct: 501 QQHHGNS--GPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSY 558
Query: 247 SDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHP 306
S NG ++S+ + + S P+PS GP G+P+ P
Sbjct: 559 SQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ---GPQ-------------GAPYPFP 602
Query: 307 PDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPR 366
P + S L + +SP T S P P + PSPG P +
Sbjct: 603 PVPTVTTSSATLSTVIATVA-SSPAGYKTASPPG---PPPYGKRAPSPGAYKTATPPGYK 658
Query: 367 PSSPP 371
P SPP
Sbjct: 659 PGSPP 663
Score = 43.1 bits (100), Expect = 0.002
Identities = 120/554 (21%), Positives = 176/554 (31%), Gaps = 118/554 (21%)
Query: 127 PPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSR 186
PPPL PP+ R+ A F P + T A ME P + +P
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEP----HPSVTPTGYHAPMEPPTSRMFQAPPGAPPPH 216
Query: 187 LTFNHDGSSRY------GPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTP 240
G+ GP+ G ++ +G Q P +P +
Sbjct: 217 PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGG------KQHPPPTTPISVSSSGASGA 270
Query: 241 EERSLPSDLAFNGDLAKAASSELPADISK--PWIPSSPAPSSENGGPASP-GLPAE---- 293
P+ G+L A PA+ P +P PA N ASP GL A+
Sbjct: 271 PPTKPPTTPVGGGNLPSAPP---PANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG 327
Query: 294 ------ASGSGPG--------------SPHLHPPDKSS--------PCHSQLLEAQTPEA 325
A G G G SPH PP SS P S + +
Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASS 387
Query: 326 SQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPP- 384
S +S + +P S ALP P P + S+ PP+ +P Q
Sbjct: 388 SSSSSSSSASPFPASQALPSYPHSFPP---------PTSLSVSNQPPKYTQPSLPSQAVW 438
Query: 385 ATSPRPLIEVGELLDLTRTFP------SGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQ 438
+ P P G LL + P +G + A Q++ + Q Q
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQ 498
Query: 439 DQEKLGGSLAALPQGQGSQLALDRPFGAESN-----WSLSQSFEWTFPTRPSGLGVWRLD 493
Q++ G+ P G A P S+ +++S S P P +
Sbjct: 499 QQQQHHGNSGPPPPG-----AFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL---- 549
Query: 494 SPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLT 553
P P ++ S + ++ SS + QG S PS S QG
Sbjct: 550 ---PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS-----QG-------- 593
Query: 554 QKGDGESQPQFPAVPLEPLPT------TEGTPGLPLQQAEERYESQEPLA----GQESPL 603
PQ P P+PT T T + + Y++ P G+ +P
Sbjct: 594 --------PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645
Query: 604 PLATREAALPILEP 617
P A + A P +P
Sbjct: 646 PGAYKTATPPGYKP 659
Score = 38.5 bits (88), Expect = 0.057
Identities = 74/317 (23%), Positives = 106/317 (33%), Gaps = 51/317 (16%)
Query: 100 APRPAVE------ASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPAS 153
AP P E AS GG +T + + + + P ++ + S
Sbjct: 20 APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79
Query: 154 ERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDG 213
E ++ + E PR + + D L G L N DGSS PR D+D
Sbjct: 80 ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSL--NDDGSS--DPRDI-------DQDN 128
Query: 214 STLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADIS--KPW 271
+ G V++ ++ S+ P P L S P D + +P
Sbjct: 129 RSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF--------PPSPQPPDSTPRQPE 180
Query: 272 IPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPC 331
P PS G +P P P S P + P H QL T P
Sbjct: 181 ASFEPHPSVTPTGYHAPMEP-------PTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPM 233
Query: 332 -PAVTPSAPSAALPDEGSRHTP-----------SPGLPAEGAPEAP-----RPSSPPPEV 374
P +A S P+ G +H P + G P P P PS+PPP
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 375 LEPHSLDQPPATSPRPL 391
+ + PP + RPL
Sbjct: 294 FPHVTPNLPPPPALRPL 310
Score = 31.2 bits (69), Expect = 9.1
Identities = 36/114 (31%), Positives = 43/114 (37%), Gaps = 32/114 (28%)
Query: 27 TGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAG 86
TG+ PG PP P KP P V GP PP GP + LPS
Sbjct: 667 TGTPPGYRGTSPPAGPGT----FKPGSPT-----VGPGPLPPAGP-SGLPS--------- 707
Query: 87 PQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGK-EEPPPLTPPARCAAP 139
LP P PA AS + + +E A + E P PPAR +P
Sbjct: 708 ----------LP--PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.128 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,520,572
Number of Sequences: 37866
Number of extensions: 5699982
Number of successful extensions: 44243
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 207
Number of HSP's successfully gapped in prelim test: 1935
Number of HSP's that attempted gapping in prelim test: 25383
Number of HSP's gapped (non-prelim): 15620
length of query: 1729
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1613
effective length of database: 13,855,062
effective search space: 22348215006
effective search space used: 22348215006
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.