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Search of human proteins with 15529980
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15529980 leucine rich repeat containing 46 [Homo sapiens]
(321 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15529980 leucine rich repeat containing 46 [Homo sapiens] 638 0.0
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 75 1e-13
gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 72 7e-13
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 63 3e-10
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 60 2e-09
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 56 5e-08
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s... 55 1e-07
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s... 55 1e-07
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s... 55 1e-07
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s... 55 1e-07
gi|206725447 leucine rich repeat containing 23 isoform a [Homo s... 54 2e-07
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa... 54 2e-07
gi|239752518 PREDICTED: similar to leucine rich repeat containin... 54 2e-07
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 52 5e-07
gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 51 1e-06
gi|61966709 leucine rich repeat containing 67 [Homo sapiens] 51 2e-06
gi|71040111 fibromodulin precursor [Homo sapiens] 50 4e-06
gi|164607156 axonemal dynein light chain 1 [Homo sapiens] 50 4e-06
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 49 5e-06
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 49 5e-06
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 49 6e-06
gi|66472382 nischarin [Homo sapiens] 48 1e-05
gi|31377705 centrosomal protein 97kDa [Homo sapiens] 48 1e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 48 1e-05
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 47 3e-05
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 47 3e-05
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 46 4e-05
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 46 4e-05
gi|5901898 leucine rich repeat containing 23 isoform b [Homo sap... 46 4e-05
gi|4826651 hypothetical protein LOC755 [Homo sapiens] 46 4e-05
>gi|15529980 leucine rich repeat containing 46 [Homo sapiens]
Length = 321
Score = 638 bits (1645), Expect = 0.0
Identities = 321/321 (100%), Positives = 321/321 (100%)
Query: 1 MSGGKSAQGPEEGGVCITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIR 60
MSGGKSAQGPEEGGVCITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIR
Sbjct: 1 MSGGKSAQGPEEGGVCITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIR 60
Query: 61 NLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSEN 120
NLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSEN
Sbjct: 61 NLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSEN 120
Query: 121 LIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDE 180
LIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDE
Sbjct: 121 LIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDE 180
Query: 181 ASSDEEFPELSGPFCSERGFLKELEQELSRHREHRQQTALTEHLLRMEMQPTLTDLPLLP 240
ASSDEEFPELSGPFCSERGFLKELEQELSRHREHRQQTALTEHLLRMEMQPTLTDLPLLP
Sbjct: 181 ASSDEEFPELSGPFCSERGFLKELEQELSRHREHRQQTALTEHLLRMEMQPTLTDLPLLP 240
Query: 241 GVPMAGDSSPSATPAQGEETVPEAVSSPQASSPTKKPCSLIPRGHQSSFWGRKGARAATA 300
GVPMAGDSSPSATPAQGEETVPEAVSSPQASSPTKKPCSLIPRGHQSSFWGRKGARAATA
Sbjct: 241 GVPMAGDSSPSATPAQGEETVPEAVSSPQASSPTKKPCSLIPRGHQSSFWGRKGARAATA 300
Query: 301 PKASVAEAPSTTKTTAKRSKK 321
PKASVAEAPSTTKTTAKRSKK
Sbjct: 301 PKASVAEAPSTTKTTAKRSKK 321
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 74.7 bits (182), Expect = 1e-13
Identities = 63/196 (32%), Positives = 92/196 (46%), Gaps = 19/196 (9%)
Query: 45 ELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVE 104
EL+ + L + I NLE LQ L +L L N I+ IENL+C+P L L +A N + VE
Sbjct: 152 ELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVE 211
Query: 105 NLLDL-PCLQF--LDLSENLI---ETLKLDEFPQSLLILNLSGNSCTNQ-DGYRELVTEA 157
++ L CL+ LDLS N + E L + E L +LNL GN Q YR VT
Sbjct: 212 DIQHLQECLRLCVLDLSHNKLSDPEILSILESMPDLRVLNLMGNPVIRQIPNYRRTVTVR 271
Query: 158 LPLLLDLDGQPV-------VERW-----ISDEEDEASSDEEFPELSGPFCSERGFLKELE 205
L L LD +PV E W +++E+ + + +K+
Sbjct: 272 LKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERQQWESRERKKITDSIEALAMIKQRA 331
Query: 206 QELSRHREHRQQTALT 221
+E R RE +++ +T
Sbjct: 332 EERKRQRESQERGEMT 347
Score = 45.1 bits (105), Expect = 9e-05
Identities = 37/105 (35%), Positives = 46/105 (43%), Gaps = 22/105 (20%)
Query: 38 KMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAG 97
K++ T T+ L +G I NLE L L+LQ N IQ+IENL LR L L
Sbjct: 101 KLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQM 160
Query: 98 NQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGN 142
N +R++ENL L Q L LNLS N
Sbjct: 161 NLLRKIENLEPL----------------------QKLDALNLSNN 183
>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
Length = 466
Score = 72.0 bits (175), Expect = 7e-13
Identities = 65/202 (32%), Positives = 102/202 (50%), Gaps = 17/202 (8%)
Query: 17 ITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIRNLEG-LQNLHSLYLQG 75
ITE LI + + E ++ + +L+EL L ++ I + +++ ++L LYLQ
Sbjct: 4 ITEDLIRR-------NAEHNDCVIFSLEELS---LHQQEIERLEHIDKWCRDLKILYLQN 53
Query: 76 NKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLI---ETLKLDEFPQ 132
N I +IEN++ + L +L+LA N I ++ENL L LDL+ N I ++K +
Sbjct: 54 NLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKNLQHNI 113
Query: 133 SLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPV-VERWISDEEDEASSDEEFPELS 191
L L L GN C + D YRE V LP L LDG+ + I +D + + + E
Sbjct: 114 HLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEPSERIKALQDYSVIEPQIREQE 173
Query: 192 GPFCSERGFLKELEQELSRHRE 213
C +R LKE Q +H+E
Sbjct: 174 KDHCLKRAKLKEEAQR--KHQE 193
>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
sapiens]
Length = 360
Score = 63.2 bits (152), Expect = 3e-10
Identities = 45/137 (32%), Positives = 70/137 (51%), Gaps = 4/137 (2%)
Query: 38 KMFHTLDELQTVRLDREGITTIRNLEG---LQNLHSLYLQGNKIQQIENLACIPSLRFLS 94
K L+ L + + +RN+EG L L L+L NKI +IENL+ + L+ L
Sbjct: 133 KKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLE 192
Query: 95 LAGNQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELV 154
L N+IR +EN+ L L+ L L +N I L+ + +L +L++ N T +G + LV
Sbjct: 193 LGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLV 252
Query: 155 TEALPLLLDLDGQPVVE 171
L L +G V+E
Sbjct: 253 -NLRELYLSHNGIEVIE 268
Score = 63.2 bits (152), Expect = 3e-10
Identities = 51/178 (28%), Positives = 86/178 (48%), Gaps = 17/178 (9%)
Query: 43 LDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQ 102
L +LQ + L I I N++ L NL SL+L NKI +++NL + +L LS+ N++ +
Sbjct: 185 LHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTK 244
Query: 103 VENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLL 162
+E L +L L+ L LS N IE ++ E L +L+++ N + L
Sbjct: 245 IEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLT-------- 296
Query: 163 DLDGQPVVERWISDEEDEASSDEEFPELSGPFCSERGFLKELEQELSRHREHRQQTAL 220
+ E W++D E+ SD EL G E +L+ L + ++R++ L
Sbjct: 297 -----ELQEFWMNDNLLESWSD--LDELKGARSLETVYLE--RNPLQKDPQYRRKVML 345
Score = 57.4 bits (137), Expect = 2e-08
Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 25/149 (16%)
Query: 42 TLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLR---------- 91
TL L+++ L + IT ++NL+ L NL L +Q N++ +IE L + +LR
Sbjct: 206 TLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIE 265
Query: 92 ------------FLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK-LDEF--PQSLLI 136
L +A N+I+++EN+ L LQ +++NL+E+ LDE +SL
Sbjct: 266 VIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLET 325
Query: 137 LNLSGNSCTNQDGYRELVTEALPLLLDLD 165
+ L N YR V ALP + +D
Sbjct: 326 VYLERNPLQKDPQYRRKVMLALPSVRQID 354
Score = 55.8 bits (133), Expect = 5e-08
Identities = 39/106 (36%), Positives = 59/106 (55%), Gaps = 10/106 (9%)
Query: 31 EDGELSEKMFHTLD-ELQTVRLDREG---------ITTIRNLEGLQNLHSLYLQGNKIQQ 80
E GE + H L +++T+ LDR+ I I E L+ + +L L+ N I+
Sbjct: 53 ERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKC 112
Query: 81 IENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK 126
IENL + SLR L L NQI+++ENL L L+ LD+S NL+ ++
Sbjct: 113 IENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIE 158
Score = 52.4 bits (124), Expect = 5e-07
Identities = 35/103 (33%), Positives = 54/103 (52%)
Query: 40 FHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQ 99
F L +++T+ L + I I NLE LQ+L L L N+I++IENL + L L ++ N
Sbjct: 94 FEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNL 153
Query: 100 IRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGN 142
+R +E + L L+ L L N I ++ L +L L N
Sbjct: 154 LRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSN 196
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 60.5 bits (145), Expect = 2e-09
Identities = 38/110 (34%), Positives = 58/110 (52%)
Query: 44 DELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQV 103
D L+ + IT I+N+ LQ L SL L N+I++I L+ + LR L L N+I+++
Sbjct: 112 DHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKI 171
Query: 104 ENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYREL 153
NL +L L LDL N I ++ L +LNL+ N ++ D L
Sbjct: 172 SNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGL 221
Score = 58.9 bits (141), Expect = 6e-09
Identities = 48/134 (35%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Query: 42 TLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIR 101
TL L+ + L + I I NLE L++L L L GN+I +IEN+ + LR L+LA N +
Sbjct: 154 TLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLS 213
Query: 102 QVENLLDLPCLQFLDLSENLIETLK-LDEFPQSLLILNLSGNSCTNQDGYRELVTEALPL 160
V+NL L L L+L N I ++ +D P L L LS N+ ++ D L +
Sbjct: 214 HVDNLNGLDSLTELNLRHNQITFVRDVDNLP-CLQHLFLSFNNISSFDSVSCLADSSSLS 272
Query: 161 LLDLDGQPVV-ERW 173
+ DG P+ E W
Sbjct: 273 DITFDGNPIAQESW 286
Score = 54.3 bits (129), Expect = 1e-07
Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 3/133 (2%)
Query: 21 LITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQ 80
L++ +FP SE+ D L L+R+ +T + G +L L Q N I +
Sbjct: 70 LVSSSLSSFPILQRSSEEKILYSDRLS---LERQKLTVCPIINGEDHLRLLNFQHNFITR 126
Query: 81 IENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLS 140
I+N++ + L L L NQI ++ L L CL+ L L +N I+ + E +SL +L+L
Sbjct: 127 IQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLH 186
Query: 141 GNSCTNQDGYREL 153
GN T + L
Sbjct: 187 GNQITKIENINHL 199
Score = 48.9 bits (115), Expect = 6e-06
Identities = 37/103 (35%), Positives = 53/103 (51%)
Query: 43 LDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQ 102
L +L ++ L I I L L+ L L L N+I++I NL + SL L L GNQI +
Sbjct: 133 LQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITK 192
Query: 103 VENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCT 145
+EN+ L L+ L+L+ N + + SL LNL N T
Sbjct: 193 IENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT 235
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 55.8 bits (133), Expect = 5e-08
Identities = 50/136 (36%), Positives = 67/136 (49%), Gaps = 10/136 (7%)
Query: 40 FHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQ 99
+H L +L LD I I LE NL L L NKI I L +P ++ L L+ NQ
Sbjct: 214 YHALTKLI---LDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLP-IKILCLSNNQ 269
Query: 100 IRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYREL-VTEAL 158
I + L DL LQ LDLS N I +L+ E L ++NL N RE+ + L
Sbjct: 270 IEMITGLEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAE---LREIEYIKNL 326
Query: 159 PLL--LDLDGQPVVER 172
P+L L+L P+ E+
Sbjct: 327 PILRVLNLLENPIQEK 342
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 56 ITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFL 115
I+ I +L L L L GN+I++I L +L LSLA N+I + L LP ++ L
Sbjct: 205 ISEICDLSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLP-IKIL 263
Query: 116 DLSENLIETLKLDEFPQSLLILNLSGNSCTNQDG 149
LS N IE + E ++L L+LS N ++ G
Sbjct: 264 CLSNNQIEMITGLEDLKALQNLDLSHNQISSLQG 297
Score = 37.7 bits (86), Expect = 0.014
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 3/109 (2%)
Query: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVEN 105
L + + +TT N + +NL N+I +I +L+ +L L L GN+I ++
Sbjct: 173 LLELNASQNNLTTFFNFKPPKNLKKADFSHNQISEICDLSAYHALTKLILDGNEIEEISG 232
Query: 106 LLDLPCLQFLDLSENLIETLK-LDEFPQSLLILNLSGNSCTNQDGYREL 153
L L L L+ N I T+ L++ P + IL LS N G +L
Sbjct: 233 LEMCNNLIHLSLANNKITTINGLNKLP--IKILCLSNNQIEMITGLEDL 279
Score = 33.1 bits (74), Expect = 0.34
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 22/119 (18%)
Query: 64 GLQNLHSLYLQGNKIQQIENLACIP----------------------SLRFLSLAGNQIR 101
G +L L L NKI+ + ++C+P +L+ + NQI
Sbjct: 147 GYVHLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPPKNLKKADFSHNQIS 206
Query: 102 QVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPL 160
++ +L L L L N IE + E +L+ L+L+ N T +G +L + L L
Sbjct: 207 EICDLSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLPIKILCL 265
Score = 31.2 bits (69), Expect = 1.3
Identities = 31/101 (30%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 45 ELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVE 104
E + + L+ E +R + LH L G+ +Q+ L+L+G + V
Sbjct: 92 ESEMLNLEEEFDGVLREEAVAKALHHLGRSGSGTEQV--------YLNLTLSGCNLIDVS 143
Query: 105 NLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCT 145
L LQ LDLS N IE L LL LN S N+ T
Sbjct: 144 ILCGYVHLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLT 184
>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/221 (27%), Positives = 99/221 (44%), Gaps = 33/221 (14%)
Query: 31 EDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGN---KIQQIENLA-- 85
E G+L+++ ++ +++LD I I NL +NL L L N KI+ +ENLA
Sbjct: 30 EAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHL 89
Query: 86 -----------------CIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK-- 126
+ +L LSL N+I ++++L L LQ L L N I+ +
Sbjct: 90 VWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNI 149
Query: 127 --LDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDEASSD 184
L F + L L+LS N + + Y+ + LP L+ LD + + + + + EA
Sbjct: 150 IYLRRF-KCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDH--TKKLAEAKHQ 206
Query: 185 EEFPELSGPFCSERGFLKELEQELSRHRE-HRQQTALTEHL 224
EL E +LE E ++ E + +TA EHL
Sbjct: 207 YSIDELKH---QENLMQAQLEDEQAQREELEKHKTAFVEHL 244
>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/221 (27%), Positives = 99/221 (44%), Gaps = 33/221 (14%)
Query: 31 EDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGN---KIQQIENLA-- 85
E G+L+++ ++ +++LD I I NL +NL L L N KI+ +ENLA
Sbjct: 30 EAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHL 89
Query: 86 -----------------CIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK-- 126
+ +L LSL N+I ++++L L LQ L L N I+ +
Sbjct: 90 VWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNI 149
Query: 127 --LDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDEASSD 184
L F + L L+LS N + + Y+ + LP L+ LD + + + + + EA
Sbjct: 150 IYLRRF-KCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDH--TKKLAEAKHQ 206
Query: 185 EEFPELSGPFCSERGFLKELEQELSRHRE-HRQQTALTEHL 224
EL E +LE E ++ E + +TA EHL
Sbjct: 207 YSIDELKH---QENLMQAQLEDEQAQREELEKHKTAFVEHL 244
>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/221 (27%), Positives = 99/221 (44%), Gaps = 33/221 (14%)
Query: 31 EDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGN---KIQQIENLA-- 85
E G+L+++ ++ +++LD I I NL +NL L L N KI+ +ENLA
Sbjct: 30 EAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHL 89
Query: 86 -----------------CIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK-- 126
+ +L LSL N+I ++++L L LQ L L N I+ +
Sbjct: 90 VWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNI 149
Query: 127 --LDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDEASSD 184
L F + L L+LS N + + Y+ + LP L+ LD + + + + + EA
Sbjct: 150 IYLRRF-KCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDH--TKKLAEAKHQ 206
Query: 185 EEFPELSGPFCSERGFLKELEQELSRHRE-HRQQTALTEHL 224
EL E +LE E ++ E + +TA EHL
Sbjct: 207 YSIDELKH---QENLMQAQLEDEQAQREELEKHKTAFVEHL 244
>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/221 (27%), Positives = 99/221 (44%), Gaps = 33/221 (14%)
Query: 31 EDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGN---KIQQIENLA-- 85
E G+L+++ ++ +++LD I I NL +NL L L N KI+ +ENLA
Sbjct: 30 EAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHL 89
Query: 86 -----------------CIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK-- 126
+ +L LSL N+I ++++L L LQ L L N I+ +
Sbjct: 90 VWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNI 149
Query: 127 --LDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDEASSD 184
L F + L L+LS N + + Y+ + LP L+ LD + + + + + EA
Sbjct: 150 IYLRRF-KCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDH--TKKLAEAKHQ 206
Query: 185 EEFPELSGPFCSERGFLKELEQELSRHRE-HRQQTALTEHL 224
EL E +LE E ++ E + +TA EHL
Sbjct: 207 YSIDELKH---QENLMQAQLEDEQAQREELEKHKTAFVEHL 244
>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/167 (29%), Positives = 76/167 (45%), Gaps = 35/167 (20%)
Query: 46 LQTVRLDREGITTIRNL--EGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQV 103
L+T+ L I + L E L +LH++ L+GN+++ + +P L+ L LA N +++V
Sbjct: 157 LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKV 215
Query: 104 ENLLDLPCLQFLDLSENLIETLK-LDEFPQSLLILNLSG--------------------- 141
E L DL L L L +N I+TL +SL LNL G
Sbjct: 216 EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRAL 275
Query: 142 ----NSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDEASSD 184
N CT++ YR+ +P L LD + +EE+ A +D
Sbjct: 276 VLLDNPCTDETSYRQEALVQMPYLERLDKE------FYEEEERAEAD 316
>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/167 (29%), Positives = 76/167 (45%), Gaps = 35/167 (20%)
Query: 46 LQTVRLDREGITTIRNL--EGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQV 103
L+T+ L I + L E L +LH++ L+GN+++ + +P L+ L LA N +++V
Sbjct: 157 LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKV 215
Query: 104 ENLLDLPCLQFLDLSENLIETLK-LDEFPQSLLILNLSG--------------------- 141
E L DL L L L +N I+TL +SL LNL G
Sbjct: 216 EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRAL 275
Query: 142 ----NSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDEASSD 184
N CT++ YR+ +P L LD + +EE+ A +D
Sbjct: 276 VLLDNPCTDETSYRQEALVQMPYLERLDKE------FYEEEERAEAD 316
>gi|239752518 PREDICTED: similar to leucine rich repeat containing
50, partial [Homo sapiens]
Length = 489
Score = 53.5 bits (127), Expect = 2e-07
Identities = 41/129 (31%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Query: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVEN 105
L + L IT I N+ L L L L N + ++NL + SL L+L NQI V +
Sbjct: 5 LDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRD 64
Query: 106 LLDLPCLQFLDLSENLI---ETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLL 162
+ +LPCLQ L LS N I +++ SL + GN + Y+ V + + L
Sbjct: 65 VDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLR 124
Query: 163 DLDGQPVVE 171
LD + + E
Sbjct: 125 QLDMKRITE 133
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/109 (35%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 67 NLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK 126
NL L L GN+I +IEN+ + LR L+LA N + V+NL L L L+L N I ++
Sbjct: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
Query: 127 -LDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVV-ERW 173
+D P L L LS N+ ++ D L + + DG P+ E W
Sbjct: 64 DVDNLP-CLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESW 111
Score = 35.0 bits (79), Expect = 0.089
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 43 LDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACI---PSLRFLSLAGNQ 99
LD L + L IT +R+++ L L L+L N I ++++C+ SL ++ GN
Sbjct: 46 LDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNP 105
Query: 100 IRQ--------VENLLDLPCLQFLDLSE 119
I Q ++N++ L L ++E
Sbjct: 106 IAQESWYKHTVLQNMMQLRQLDMKRITE 133
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 52.4 bits (124), Expect = 5e-07
Identities = 47/129 (36%), Positives = 67/129 (51%), Gaps = 10/129 (7%)
Query: 26 NLTFPEDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLH--SLYLQGNKIQQIE- 82
NL++ + E+ F L LQ V L+ +T + +L G + H SL+LQ NKI+ +E
Sbjct: 74 NLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSL-GAASSHVVSLFLQHNKIRSVEG 132
Query: 83 -NLACIPSLRFLSLAGNQIRQVENLL--DLPCLQFLDLSENLIETLKL---DEFPQSLLI 136
L SL L L+ N I +V N P ++ L+L+ N I TL+L D +SLL
Sbjct: 133 SQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLT 192
Query: 137 LNLSGNSCT 145
L LS N T
Sbjct: 193 LRLSKNRIT 201
>gi|4504379 leucine-rich repeat-containing G protein-coupled
receptor 5 [Homo sapiens]
Length = 907
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/108 (36%), Positives = 56/108 (51%), Gaps = 5/108 (4%)
Query: 40 FHTLDELQTVRLDREG-ITTIRNLEGLQNLHSLYLQGNKIQQIENLAC--IPSLRFLSLA 96
F L EL+T+ L+ IT +L G NL SL L G +I + C +P+L+ L L+
Sbjct: 301 FQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLS 360
Query: 97 GNQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQ--SLLILNLSGN 142
N + + + LQ +DL N I +K+D F Q SL LNL+ N
Sbjct: 361 YNLLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWN 408
>gi|61966709 leucine rich repeat containing 67 [Homo sapiens]
Length = 228
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/160 (34%), Positives = 71/160 (44%), Gaps = 19/160 (11%)
Query: 17 ITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGN 76
IT + +N+ ED L + L + L I+ I NL NL LYLQ N
Sbjct: 30 ITHINFSDKNIDAIEDLSLCKN-------LSVLYLYDNCISQITNLNYATNLTHLYLQNN 82
Query: 77 KIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCL-------QFLDLSENLI-ETLKLD 128
I IENL + L L L GN I +E L L L Q L L E L+ + L
Sbjct: 83 CISCIENLRSLKKLEKLYLGGNYIAVIEGLEGLGELRELHVENQRLPLGEKLLFDPRTLH 142
Query: 129 EFPQSLLILNLSGNSCTNQDGYREL-VTEALPLLLDLDGQ 167
+SL ILN+S N N D +L + E L L+ +D Q
Sbjct: 143 SLAKSLCILNISNN---NIDDITDLELLENLNQLIAVDNQ 179
Score = 42.4 bits (98), Expect = 6e-04
Identities = 30/90 (33%), Positives = 42/90 (46%)
Query: 37 EKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLA 96
E + L ++ + + I I +L +NL LYL N I QI NL +L L L
Sbjct: 21 ETISQCLKKITHINFSDKNIDAIEDLSLCKNLSVLYLYDNCISQITNLNYATNLTHLYLQ 80
Query: 97 GNQIRQVENLLDLPCLQFLDLSENLIETLK 126
N I +ENL L L+ L L N I ++
Sbjct: 81 NNCISCIENLRSLKKLEKLYLGGNYIAVIE 110
>gi|71040111 fibromodulin precursor [Homo sapiens]
Length = 376
Score = 49.7 bits (117), Expect = 4e-06
Identities = 43/124 (34%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Query: 46 LQTVRLDREGITTIRN--LEGLQNLHSLYLQGNKIQQI-ENLACIPSLRFLSLAGNQIRQ 102
L+ + LD I+ + N LEGL+NL +LYLQ N+IQ++ ++ + SL L L+ N +R+
Sbjct: 178 LRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRK 237
Query: 103 VENLLDLPCLQFLDLSENLIETLKLDEF--PQSLLILNLSGNSCTNQDGYRELVTEALPL 160
V + L L+ L + N + T+ F LL + LS NS TN + L
Sbjct: 238 VPDGLP-SALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLL 296
Query: 161 LLDL 164
LDL
Sbjct: 297 ELDL 300
Score = 32.3 bits (72), Expect = 0.58
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 9/62 (14%)
Query: 67 NLHSLYLQGNKIQQ--------IENLACIPSLRFLSLAGNQIRQVENLLDLP-CLQFLDL 117
NL +LYLQGN+I + + ++ L+ L L GN+I++ D P CL+ L
Sbjct: 314 NLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASL 373
Query: 118 SE 119
E
Sbjct: 374 IE 375
>gi|164607156 axonemal dynein light chain 1 [Homo sapiens]
Length = 190
Score = 49.7 bits (117), Expect = 4e-06
Identities = 46/155 (29%), Positives = 77/155 (49%), Gaps = 14/155 (9%)
Query: 37 EKMFHTLDEL---QTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACI-PSLRF 92
EKM +L L + + L I I NL GL+NL L L N I+ + L + +L
Sbjct: 38 EKMDASLSMLANCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVGDTLEE 97
Query: 93 LSLAGNQIRQVENLLDLPCLQFLDLSENLI----ETLKLDEFP---QSLLILNLSGNSCT 145
L ++ N I +++ + + L+ L +S NL+ E +KL E P + + N +
Sbjct: 98 LWISYNFIEKLKGIHIMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFVGNPLEEKHS 157
Query: 146 NQDGYRELVTEALPLLLDLDGQPVVERWISDEEDE 180
++ + E T+ +P L LDG PV++ DEE++
Sbjct: 158 AENNWIEEATKRVPKLKKLDGTPVIK---GDEEED 189
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
[Homo sapiens]
Length = 1722
Score = 49.3 bits (116), Expect = 5e-06
Identities = 35/127 (27%), Positives = 65/127 (51%), Gaps = 6/127 (4%)
Query: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLAC--IPSLRFLSLAGNQIRQV 103
LQ ++L ++ + +LE L L L+L N I +E + +P L+ ++++ N + ++
Sbjct: 1015 LQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKI 1074
Query: 104 ENLLDLPCLQFLDLSENLIETLKLD----EFPQSLLILNLSGNSCTNQDGYRELVTEALP 159
L L+ LD+S N + LK + SL L+L+GN + +R+ + + LP
Sbjct: 1075 VPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLP 1134
Query: 160 LLLDLDG 166
L L+G
Sbjct: 1135 ALRILNG 1141
Score = 32.3 bits (72), Expect = 0.58
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 48 TVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLL 107
T LD+ I + LQ + ++ Q + LA +L+FLSL + + +L
Sbjct: 778 TPALDKLEILRCGPWDTLQQVTTVTFQDLPGCVLSTLAECTNLQFLSLRRCGLTSLHSLS 837
Query: 108 DLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDG 149
+ L+++D EN IE ++ + ++L ++ L+ N T+ G
Sbjct: 838 NCKKLKYIDAQENHIEAIECENL-ENLCVVLLNKNQLTSLHG 878
Score = 31.6 bits (70), Expect = 0.99
Identities = 22/71 (30%), Positives = 33/71 (46%)
Query: 84 LACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNS 143
L + +L+ L L NQ+ + L D P + +LD S N + ++ E L IL L GN
Sbjct: 965 LESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNY 1024
Query: 144 CTNQDGYRELV 154
+ LV
Sbjct: 1025 LSELPSLENLV 1035
Score = 28.9 bits (63), Expect = 6.4
Identities = 14/39 (35%), Positives = 23/39 (58%)
Query: 43 LDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQI 81
L+ L V L++ +T++ L+G N+ L L NKI +I
Sbjct: 860 LENLCVVLLNKNQLTSLHGLDGCTNIQCLELSYNKITRI 898
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2
[Homo sapiens]
Length = 1336
Score = 49.3 bits (116), Expect = 5e-06
Identities = 35/127 (27%), Positives = 65/127 (51%), Gaps = 6/127 (4%)
Query: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLAC--IPSLRFLSLAGNQIRQV 103
LQ ++L ++ + +LE L L L+L N I +E + +P L+ ++++ N + ++
Sbjct: 1015 LQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKI 1074
Query: 104 ENLLDLPCLQFLDLSENLIETLKLD----EFPQSLLILNLSGNSCTNQDGYRELVTEALP 159
L L+ LD+S N + LK + SL L+L+GN + +R+ + + LP
Sbjct: 1075 VPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLP 1134
Query: 160 LLLDLDG 166
L L+G
Sbjct: 1135 ALRILNG 1141
Score = 32.3 bits (72), Expect = 0.58
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 48 TVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLL 107
T LD+ I + LQ + ++ Q + LA +L+FLSL + + +L
Sbjct: 778 TPALDKLEILRCGPWDTLQQVTTVTFQDLPGCVLSTLAECTNLQFLSLRRCGLTSLHSLS 837
Query: 108 DLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDG 149
+ L+++D EN IE ++ + ++L ++ L+ N T+ G
Sbjct: 838 NCKKLKYIDAQENHIEAIECENL-ENLCVVLLNKNQLTSLHG 878
Score = 31.6 bits (70), Expect = 0.99
Identities = 22/71 (30%), Positives = 33/71 (46%)
Query: 84 LACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNS 143
L + +L+ L L NQ+ + L D P + +LD S N + ++ E L IL L GN
Sbjct: 965 LESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNY 1024
Query: 144 CTNQDGYRELV 154
+ LV
Sbjct: 1025 LSELPSLENLV 1035
Score = 28.9 bits (63), Expect = 6.4
Identities = 14/39 (35%), Positives = 23/39 (58%)
Query: 43 LDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQI 81
L+ L V L++ +T++ L+G N+ L L NKI +I
Sbjct: 860 LENLCVVLLNKNQLTSLHGLDGCTNIQCLELSYNKITRI 898
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 48.9 bits (115), Expect = 6e-06
Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 35/163 (21%)
Query: 40 FHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQ-QIENLA-CIPSLRFLSLAG 97
F L+ L T+ + G+T+I NL L L L L N++ +E LA P+L L+L+G
Sbjct: 41 FEELEFLSTINV---GLTSIANLPKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSG 97
Query: 98 NQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEA 157
N+I+ DLS IE LK E +SL + N TN + YRE V +
Sbjct: 98 NKIK--------------DLS--TIEPLKKLENLKSLDLFNC---EVTNLNDYRENVFKL 138
Query: 158 LPLLLDLDG---------QPVVERWIS--DEEDEASSDEEFPE 189
LP L LDG E ++ D+E+E +EE+ E
Sbjct: 139 LPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDE 181
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 48.1 bits (113), Expect = 1e-05
Identities = 36/124 (29%), Positives = 64/124 (51%), Gaps = 3/124 (2%)
Query: 4 GKSAQGPEEGGVCITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIRNLE 63
G + +GP + +AL T +L+ E+ E + + +++ + L G+ + NL+
Sbjct: 272 GTTLEGPVTAVIPTWQALTTL-DLSHNSISEIDESV-KLIPKIEFLDLSHNGLLVVDNLQ 329
Query: 64 GLQNLHSLYLQGNKIQQIENLAC-IPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLI 122
L NL L L NK+ +E L + +++ L+LAGN + + L L L LDL +N I
Sbjct: 330 HLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRI 389
Query: 123 ETLK 126
E ++
Sbjct: 390 EQME 393
Score = 43.1 bits (100), Expect = 3e-04
Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 2/90 (2%)
Query: 66 QNLHSLYLQGNKIQQI-ENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIET 124
Q L +L L N I +I E++ IP + FL L+ N + V+NL L L LDLS N + +
Sbjct: 287 QALTTLDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSS 346
Query: 125 LK-LDEFPQSLLILNLSGNSCTNQDGYREL 153
L+ L ++ LNL+GN + G +L
Sbjct: 347 LEGLHTKLGNIKTLNLAGNLLESLSGLHKL 376
>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
Length = 865
Score = 47.8 bits (112), Expect = 1e-05
Identities = 32/111 (28%), Positives = 61/111 (54%)
Query: 45 ELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVE 104
++ T+ LD+ I + NLE + L L + N++ ++ +A + LR L+L N I VE
Sbjct: 37 DIHTLILDKNQIIKLENLEKCKRLIQLSVANNRLVRMMGVAKLTLLRVLNLPHNSIGCVE 96
Query: 105 NLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVT 155
L +L L++L+L+ N ++ ++ +L L+LS N+ + +LV+
Sbjct: 97 GLKELVHLEWLNLAGNNLKAMEQINSCTALQHLDLSDNNISQIGDLSKLVS 147
Score = 37.4 bits (85), Expect = 0.018
Identities = 27/83 (32%), Positives = 46/83 (55%)
Query: 61 NLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSEN 120
NL ++H+L L N+I ++ENL L LS+A N++ ++ + L L+ L+L N
Sbjct: 31 NLPCEADIHTLILDKNQIIKLENLEKCKRLIQLSVANNRLVRMMGVAKLTLLRVLNLPHN 90
Query: 121 LIETLKLDEFPQSLLILNLSGNS 143
I ++ + L LNL+GN+
Sbjct: 91 SIGCVEGLKELVHLEWLNLAGNN 113
Score = 32.7 bits (73), Expect = 0.44
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENL-ACIP-SLRFLSLAGNQIRQV 103
LQ + L I+ I +L L +L +L L GN I + A +P SL LSLA N+IR +
Sbjct: 126 LQHLDLSDNNISQIGDLSKLVSLKTLLLHGNIITSLRMAPAYLPRSLAILSLAENEIRDL 185
Query: 104 ENLLDLPCLQFLD 116
+ L L L+
Sbjct: 186 NEISFLASLTELE 198
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 47.8 bits (112), Expect = 1e-05
Identities = 52/159 (32%), Positives = 79/159 (49%), Gaps = 15/159 (9%)
Query: 17 ITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREG---ITTIRNLEGLQNLHSLYL 73
ITEALI K LT ++ L + + + L ++G I NLE L L L
Sbjct: 83 ITEALIKK--LTKQDNLALIKSL--------NLSLSKDGGKKFKYIENLEKCVKLEVLNL 132
Query: 74 QGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK--LDEFP 131
N I +IE L + LR L+L+ N+I ++E + ++ LQ L+L+ N IE + L +
Sbjct: 133 SYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKL 192
Query: 132 QSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVV 170
+SL +LNL GN ++ +L + L L PVV
Sbjct: 193 KSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVV 231
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/154 (31%), Positives = 74/154 (48%), Gaps = 15/154 (9%)
Query: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKI-QQIENLA-CIPSLRFLSLAGNQIRQV 103
L+ + L G+ ++ NL L L L L N+I ++ LA +P+L L+L+GN+++ +
Sbjct: 44 LEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDI 103
Query: 104 ---ENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPL 160
E L L CL+ LDL E L+++ +S+ L T DGY EA
Sbjct: 104 STLEPLKKLECLKSLDLFN--CEVTNLNDYRESVFKLL---PQLTYLDGYDREDQEAPDS 158
Query: 161 LLDLDGQPVVERWIS-----DEEDEASSDEEFPE 189
++DG E DE+DE +EEF E
Sbjct: 159 DAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDE 192
Score = 45.4 bits (106), Expect = 7e-05
Identities = 49/145 (33%), Positives = 67/145 (46%), Gaps = 20/145 (13%)
Query: 62 LEGLQ----NLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLL--DLPCLQFL 115
+EGL NL L L + + NL +P L+ L L+ N+I ++L LP L L
Sbjct: 34 IEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHL 93
Query: 116 DLSENL---IETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDG------ 166
+LS N I TL+ + + L L+L TN + YRE V + LP L LDG
Sbjct: 94 NLSGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQ 153
Query: 167 -----QPVVERWISDEEDEASSDEE 186
V+ +EEDE DEE
Sbjct: 154 EAPDSDAEVDGVDEEEEDEEGEDEE 178
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 46.6 bits (109), Expect = 3e-05
Identities = 55/185 (29%), Positives = 88/185 (47%), Gaps = 33/185 (17%)
Query: 32 DGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQ-IENLA--CIP 88
+GE+ E + T EL+ + + ++++ L L L L L N I +E LA C P
Sbjct: 31 NGEI-EGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKC-P 88
Query: 89 SLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQD 148
+L +L+L+GN+I+ L ++ +NL ++L L+L TN +
Sbjct: 89 NLTYLNLSGNKIKD---------LSTVEALQNL----------KNLKSLDLFNCEITNLE 129
Query: 149 GYRELVTEALPLLLDLDG--QPVVERWISDEEDEASSDEEFPE----LSGPFCSERGFLK 202
YRE + E L + LDG Q E S+EED+ DE+ E +GP G+ +
Sbjct: 130 DYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP---PEGYEE 186
Query: 203 ELEQE 207
E E+E
Sbjct: 187 EEEEE 191
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 46.2 bits (108), Expect = 4e-05
Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 22/167 (13%)
Query: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLAC--IPSLRFLSLAGNQIRQV 103
L+ +RL G+ +I NL L L L N+I N++ +P+L L+L+G +++ +
Sbjct: 64 LEFLRLINVGLISISNLPKLPKLKKFVLSENRIFGGLNMSAEKLPNLTHLNLSGKKLKDI 123
Query: 104 ---ENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPL 160
E L L CL+ LDL E + L+++ +S+ L L +C D Y EA
Sbjct: 124 STLEPLKKLECLKSLDLFN--CEVINLNDYQESVFKL-LPQLTCL--DTYDPEDQEA--- 175
Query: 161 LLDLDGQPVVERWISDEEDEASSDEEFPELSGPFCSERGFLKELEQE 207
D D Q V+ +EEDE DE+ E +E G +EL++E
Sbjct: 176 -PDSDAQ--VDGVDKEEEDEEGEDEKDXE------NEDGEEEELDEE 213
>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 46.2 bits (108), Expect = 4e-05
Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 22/167 (13%)
Query: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLAC--IPSLRFLSLAGNQIRQV 103
L+ +RL G+ +I NL L L L N+I N++ +P+L L+L+G +++ +
Sbjct: 64 LEFLRLINVGLISISNLPKLPKLKKFVLSENRIFGGLNMSAEKLPNLTHLNLSGKKLKDI 123
Query: 104 ---ENLLDLPCLQFLDLSENLIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPL 160
E L L CL+ LDL E + L+++ +S+ L L +C D Y EA
Sbjct: 124 STLEPLKKLECLKSLDLFN--CEVINLNDYQESVFKL-LPQLTCL--DTYDPEDQEA--- 175
Query: 161 LLDLDGQPVVERWISDEEDEASSDEEFPELSGPFCSERGFLKELEQE 207
D D Q V+ +EEDE DE+ E +E G +EL++E
Sbjct: 176 -PDSDAQ--VDGVDKEEEDEEGEDEKDXE------NEDGEEEELDEE 213
>gi|5901898 leucine rich repeat containing 23 isoform b [Homo
sapiens]
Length = 312
Score = 46.2 bits (108), Expect = 4e-05
Identities = 35/97 (36%), Positives = 54/97 (55%), Gaps = 4/97 (4%)
Query: 46 LQTVRLDREGITTIRNL--EGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQV 103
L+T+ L I + L E L +LH++ L+GN+++ + +P L+ L LA N +++V
Sbjct: 157 LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKV 215
Query: 104 ENLLDLPCLQFLDLSENLIETLK-LDEFPQSLLILNL 139
E L DL L L L +N I+TL +SL LNL
Sbjct: 216 EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNL 252
>gi|4826651 hypothetical protein LOC755 [Homo sapiens]
Length = 256
Score = 46.2 bits (108), Expect = 4e-05
Identities = 44/150 (29%), Positives = 65/150 (43%), Gaps = 7/150 (4%)
Query: 49 VRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLD 108
++L R+ + T L ++ L G+++ I +PSL ++L+ N I +E +
Sbjct: 1 MKLTRKMVLTRAKASELHSVRKLNCWGSRLTDISICQEMPSLEVITLSVNSISTLEPVSR 60
Query: 109 LPCLQFLDLSENLIETLK----LDEFPQSLLILNLSGNSC--TNQDGYRELVTEALPLLL 162
L L L N I +L L P+ L +L L+ N C T+ YR V LP L
Sbjct: 61 CQRLSELYLRRNRIPSLAELFYLKGLPR-LRVLWLAENPCCGTSPHRYRMTVLRTLPRLQ 119
Query: 163 DLDGQPVVERWISDEEDEASSDEEFPELSG 192
LD Q V E +S E PE G
Sbjct: 120 KLDNQAVTEEELSRALSEGEEITAAPEREG 149
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,922,860
Number of Sequences: 37866
Number of extensions: 639092
Number of successful extensions: 3789
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 3408
Number of HSP's gapped (non-prelim): 560
length of query: 321
length of database: 18,247,518
effective HSP length: 102
effective length of query: 219
effective length of database: 14,385,186
effective search space: 3150355734
effective search space used: 3150355734
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.