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Search of human proteins with 15431318
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15431318 keratin 38 [Homo sapiens]
(456 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15431318 keratin 38 [Homo sapiens] 924 0.0
gi|55770882 keratin 37 [Homo sapiens] 820 0.0
gi|14917115 keratin 31 [Homo sapiens] 495 e-140
gi|10337581 type I hair keratin 3B [Homo sapiens] 492 e-139
gi|14917117 keratin 33A [Homo sapiens] 491 e-139
gi|14917119 keratin 34 [Homo sapiens] 475 e-134
gi|116488398 keratin 32 [Homo sapiens] 463 e-130
gi|4504927 keratin 36 [Homo sapiens] 461 e-130
gi|94538345 keratin 35 [Homo sapiens] 457 e-128
gi|125490370 type I hair keratin KA36 [Homo sapiens] 413 e-115
gi|148277620 type I hair keratin KA35 [Homo sapiens] 394 e-110
gi|4557701 keratin 17 [Homo sapiens] 325 7e-89
gi|15431310 keratin 14 [Homo sapiens] 322 3e-88
gi|24430190 keratin 15 [Homo sapiens] 319 3e-87
gi|131412225 keratin 13 isoform a [Homo sapiens] 318 8e-87
gi|24430192 keratin 16 [Homo sapiens] 318 8e-87
gi|131412228 keratin 13 isoform b [Homo sapiens] 313 2e-85
gi|24234699 keratin 19 [Homo sapiens] 311 6e-85
gi|195972866 keratin 10 [Homo sapiens] 291 1e-78
gi|4557699 keratin 12 [Homo sapiens] 281 9e-76
gi|27894337 keratin 20 [Homo sapiens] 278 7e-75
gi|114431246 keratin 25D [Homo sapiens] 263 3e-70
gi|192807292 keratin 24 [Homo sapiens] 259 4e-69
gi|153945736 keratin 27 [Homo sapiens] 254 1e-67
gi|40354195 keratin 18 [Homo sapiens] 250 2e-66
gi|4557888 keratin 18 [Homo sapiens] 250 2e-66
gi|27894339 keratin 23 [Homo sapiens] 246 3e-65
gi|31559829 keratin 25 [Homo sapiens] 246 4e-65
gi|55956899 keratin 9 [Homo sapiens] 240 2e-63
gi|31559815 keratin 26 [Homo sapiens] 239 5e-63
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 924 bits (2387), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGST 60
MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGST
Sbjct: 1 MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGST 60
Query: 61 PLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLE 120
PLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLE
Sbjct: 61 PLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLE 120
Query: 121 KVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQID 180
KVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQID
Sbjct: 121 KVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQID 180
Query: 181 NAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
NAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS
Sbjct: 181 NAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
Query: 241 NHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSE 300
NHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSE
Sbjct: 241 NHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSE 300
Query: 301 GISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELA 360
GISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELA
Sbjct: 301 GISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELA 360
Query: 361 QMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPC 420
QMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPC
Sbjct: 361 QMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPC 420
Query: 421 STSPSCVTAPCAPRPSCGPCTTCGPTCGASTTGSRF 456
STSPSCVTAPCAPRPSCGPCTTCGPTCGASTTGSRF
Sbjct: 421 STSPSCVTAPCAPRPSCGPCTTCGPTCGASTTGSRF 456
>gi|55770882 keratin 37 [Homo sapiens]
Length = 449
Score = 820 bits (2119), Expect = 0.0
Identities = 412/453 (90%), Positives = 423/453 (93%), Gaps = 5/453 (1%)
Query: 1 MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGST 60
MTS YS+SSCPLGCTMAPGARNV VSPID+GCQP AEAN A MCLLANVAHANRVRVGST
Sbjct: 1 MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGST 60
Query: 61 PLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLE 120
PLGRPSLCLPPT HTACPLPGTCHIPGNIGICGAYG+NTLNGHEKETM+FLNDRLANYLE
Sbjct: 61 PLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLE 120
Query: 121 KVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQID 180
KVRQLEQENAELE TLLERSKCHESTVCPDYQSYF TIEELQQKILCSKAENARLIVQID
Sbjct: 121 KVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQID 180
Query: 181 NAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
NAKLAADDFRIKLESERSL QLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS
Sbjct: 181 NAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
Query: 241 NHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSE 300
NHEQEVKILRSQLGEK RIELDIEPTIDLNRVLGEMRAQYEAM+ETN QDVEQWFQAQSE
Sbjct: 241 NHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSE 300
Query: 301 GISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELA 360
GISLQ MSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDR+GTELA
Sbjct: 301 GISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELA 360
Query: 361 QMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPC 420
QMQSLISN+EEQLSEIRADLERQNQEYQVLLDVK RLENEIATYRNLLESEDCKLPCNPC
Sbjct: 361 QMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPC 420
Query: 421 STSPSCVTAPCAPRPSCGPCTTCGPTCGASTTG 453
ST SC + PSCGP T P+ ++ G
Sbjct: 421 STPASCTSC-----PSCGPVTGGSPSGHGASMG 448
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 495 bits (1274), Expect = e-140
Identities = 248/394 (62%), Positives = 308/394 (78%), Gaps = 20/394 (5%)
Query: 68 CLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQ 127
C+PP+CH+ C LPG C+IP N+ C + E + NG EKETMQFLNDRLA+YLEKVRQLE+
Sbjct: 21 CVPPSCHS-CTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
Query: 128 ENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAAD 187
+NAELE + ERS+ E +CP YQSYF TIEELQQKILC+K+ENARL+VQIDNAKLAAD
Sbjct: 80 DNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAAD 139
Query: 188 DFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247
DFR K ++E SLRQLVE+D G +++LD+ TL K+DLEAQ ESLKEE L LKSNHEQEV
Sbjct: 140 DFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVN 199
Query: 248 ILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDM 307
LR QLG++L +E+D PT+DLNRVL E R+QYEA++ETNR++VEQWF Q+E ++ Q +
Sbjct: 200 TLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVV 259
Query: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLIS 367
S SE+LQ Q+EI+ELR TVNALE+E QAQH L+D L+N+L E+E R+ ++L+Q+QSLI+
Sbjct: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLIT 319
Query: 368 NVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTSPSC- 426
NVE QL+EIR+DLERQNQEYQVLLDV+ RLE EI TYR+LLESEDC LP NPC+T+ +C
Sbjct: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACS 379
Query: 427 ------------------VTAPCAPRPSCGPCTT 442
PCAPRP CGPC +
Sbjct: 380 KPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNS 413
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 492 bits (1267), Expect = e-139
Identities = 247/384 (64%), Positives = 305/384 (79%), Gaps = 8/384 (2%)
Query: 68 CLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQ 127
C+PP+CH LPG C+IP N+ C + E + NG EKETMQFLNDRLA+YLEKVRQLE+
Sbjct: 21 CVPPSCH-GYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
Query: 128 ENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAAD 187
+NAELE + ERS+ E +CP YQSYF TIEELQQKILCSK+ENARL+VQIDNAKLAAD
Sbjct: 80 DNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAAD 139
Query: 188 DFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247
DFR K ++E+SLRQLVE+D +++LD+ TL ++DLEAQ ESLKEE LSLK NHEQEV
Sbjct: 140 DFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVN 199
Query: 248 ILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDM 307
LR QLG++L +E+D P +DLN+VL E R QYEA++ETNR++VEQWF Q+E ++ Q +
Sbjct: 200 TLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVV 259
Query: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLIS 367
S SE+LQ Q+EI+ELR TVNALE+E QAQH L+ L+N+L E+E R+ ++L+Q+QSLI+
Sbjct: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLIT 319
Query: 368 NVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTS---- 423
NVE QL+EIR+DLERQNQEYQVLLDV+ RLE EI TYR+LLESEDCKLP NPC+T+
Sbjct: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACE 379
Query: 424 ---PSCVTAPCAPRPSCGPCTTCG 444
SCVT PC PR CGPC T G
Sbjct: 380 KPIGSCVTNPCGPRSRCGPCNTFG 403
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 491 bits (1263), Expect = e-139
Identities = 245/384 (63%), Positives = 305/384 (79%), Gaps = 8/384 (2%)
Query: 68 CLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQ 127
C+PP+CH C LPG C+IP N+ C + E + NG EKETMQFLNDRLA+YLEKVRQLE+
Sbjct: 21 CVPPSCH-GCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
Query: 128 ENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAAD 187
+NAELE + ERS+ E VC YQSYF TIEELQQKILCSK+ENARL+VQIDNAKLA+D
Sbjct: 80 DNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASD 139
Query: 188 DFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247
DFR K E+E SLRQLVE+D G +++LD+ TL ++DLEAQ ESLKEE L LK NHEQEV
Sbjct: 140 DFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVN 199
Query: 248 ILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDM 307
LR QLG++L +E+D PT+DLN+VL E R+QYEA++ETNR++VEQWF Q+E ++ Q +
Sbjct: 200 TLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVV 259
Query: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLIS 367
S SE+LQ Q+EI+ELR TVNALE+E QAQH L+D L+N+L E+E R+ ++L+Q+Q LI+
Sbjct: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLIT 319
Query: 368 NVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTSPS-- 425
NVE QL+EIR+DLERQNQEYQVLLDV+ RLE EI TYR+LLESEDCKLP NPC+T+ +
Sbjct: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACD 379
Query: 426 -----CVTAPCAPRPSCGPCTTCG 444
C++ PC R CGPC T G
Sbjct: 380 KSTGPCISNPCGLRARCGPCNTFG 403
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 475 bits (1222), Expect = e-134
Identities = 237/380 (62%), Positives = 299/380 (78%), Gaps = 8/380 (2%)
Query: 68 CLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQ 127
C+PP+CH LPG C+IP N+ C + E + NG EKETMQFLNDRLA+YLEKVRQLE+
Sbjct: 63 CVPPSCH-GYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 121
Query: 128 ENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAAD 187
+NAELE + ERS+ E +CP YQSYF TIEELQQKILC+KAENARL+V IDNAKLA+D
Sbjct: 122 DNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASD 181
Query: 188 DFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247
DFR K ++E+SLR LVE+D +++LD+ TL K+DLE+Q ESL+EE + LK NHE+EV
Sbjct: 182 DFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVN 241
Query: 248 ILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDM 307
LRSQLG++L +E+D PT+DLN+VL E R+QYEA++E NR++VEQWF Q+E ++ Q +
Sbjct: 242 TLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVV 301
Query: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLIS 367
S SE+LQ CQ+EI+ELR TVNALE+E QAQH L+D L+N+L E+E + ++L+Q+QSLI+
Sbjct: 302 SSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLIT 361
Query: 368 NVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTSPSCV 427
NVE QL+EIR DLERQNQEYQVLLDV+ RLE EI TYR+LLESEDCKLPCNPC+T+
Sbjct: 362 NVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCATTN--- 418
Query: 428 TAPCAPRPSCGPCTTCGPTC 447
A SCGPC T C
Sbjct: 419 ----ASGNSCGPCGTSQKGC 434
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 463 bits (1191), Expect = e-130
Identities = 246/401 (61%), Positives = 299/401 (74%), Gaps = 14/401 (3%)
Query: 65 PSLCLPPT-----CHTACPLPGTCH----IPGNIGICGAYGENTLNGHEKETMQFLNDRL 115
PS+CLP T C + L +C I G++G Y E NG+EKETMQFLNDRL
Sbjct: 48 PSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRL 107
Query: 116 ANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARL 175
A+YL +VRQLEQENAELE+ + E S T+ PDYQS+F TIEELQQKILC+KAENAR+
Sbjct: 108 ASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARM 167
Query: 176 IVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQ 235
+V IDNAKLAADDFR K E+E ++RQLVEAD G +++LDD TL KADLEAQ ESLKEE
Sbjct: 168 VVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEEL 227
Query: 236 LSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWF 295
+ LK NHE+EV LR QLG++L IE+D P +DL RVL EMR QYEAM+E NR+DVE+WF
Sbjct: 228 MCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWF 287
Query: 296 QAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRF 355
Q E ++ Q + SE+LQ QS+I++LR TVN LE+E QAQH+L+D L+N+L E+E R+
Sbjct: 288 NMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARY 347
Query: 356 GTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKL 415
++LAQMQ +I+NVE QL+EIRADLERQNQEYQVLLDV+ RLE EI TYR+LLE+EDCKL
Sbjct: 348 SSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKL 407
Query: 416 PCNPCSTSPSCVT---APCAPRPSCGPCTTCGPTCGASTTG 453
PCNPCST PSC T +PC PR C P T G C G
Sbjct: 408 PCNPCST-PSCTTCVPSPCVPRTVCVP-RTVGMPCSPCPQG 446
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 461 bits (1185), Expect = e-130
Identities = 250/450 (55%), Positives = 312/450 (69%), Gaps = 23/450 (5%)
Query: 2 TSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGSTP 61
T ++S+ S C A G VS C+ + A A + + R G +
Sbjct: 7 TPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAA--------GYISSARSGLSG 58
Query: 62 LGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEK 121
LG CLP + L CH G +G G + E + NG EKETMQFLNDRLANYLEK
Sbjct: 59 LGS---CLPGSY-----LSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEK 110
Query: 122 VRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDN 181
VRQLE+ENAELE+ + E + +CPDYQSYF TIE+ QQKIL +K+ENARL++QIDN
Sbjct: 111 VRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDN 170
Query: 182 AKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSN 241
AKLAADDFR K E+E SLRQLVEAD G +++LD+ TL KADLEAQ ESLKEE + LK N
Sbjct: 171 AKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKN 230
Query: 242 HEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEG 301
HE+EV +LR QLG++L +E+D P +DLN++L +MR QYEA++E NR+DVE WF Q+E
Sbjct: 231 HEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEE 290
Query: 302 ISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQ 361
++ Q +S SE+LQCCQ+EI+ELR TVNALE+E QAQH++++ L+++L E E R+ ++LAQ
Sbjct: 291 LNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQ 350
Query: 362 MQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCS 421
MQ LISNVE QLSEIR DLERQNQEYQVLLDVK RLE EIATYR+LLE EDCKLP PC+
Sbjct: 351 MQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCA 410
Query: 422 TS-------PSCVTAPCAPRPSCGPCTTCG 444
T+ PS PC P C P G
Sbjct: 411 TACKPVIRVPSVPPVPCVPSVPCTPAPQVG 440
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 457 bits (1175), Expect = e-128
Identities = 252/450 (56%), Positives = 307/450 (68%), Gaps = 39/450 (8%)
Query: 1 MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGST 60
+++ YSSSSC L +++P AR+ S + +G
Sbjct: 28 VSAMYSSSSCKLP-SLSPVARSFSACSVGLGRSSY------------------------- 61
Query: 61 PLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLE 120
R + CLP C LP G G +GE L G+EKETMQ LNDRLA YLE
Sbjct: 62 ---RATSCLPALC-----LPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLE 113
Query: 121 KVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQID 180
KVRQLEQENA LE+ + E + +CPDYQSYF TIEELQ+K LCSKAENARL+V+ID
Sbjct: 114 KVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEID 173
Query: 181 NAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
NAKLAADDFR K E+E SLRQLVE+D G +++LDD TL K+DLEAQ ESLKEE L LK
Sbjct: 174 NAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKK 233
Query: 241 NHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSE 300
NHE+EV LR QLG++L +E+D P +DLNRVL EMR QYE ++E NR+D E W QSE
Sbjct: 234 NHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSE 293
Query: 301 GISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELA 360
++ Q +S SE+LQ CQ+EI+ELR TVNALE+E QAQH+++D L+++L E E R+ ++LA
Sbjct: 294 ELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLA 353
Query: 361 QMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPC 420
QMQ +I+NVE QL+EIRADLERQNQEYQVLLDV+ RLE EI TYR LLESED KLPCNPC
Sbjct: 354 QMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPC 413
Query: 421 ST--SPSCVTAPCAPRPSCGPC---TTCGP 445
+ SPS PC P SCGP T C P
Sbjct: 414 APDYSPSKSCLPCLPAASCGPSAARTNCSP 443
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 413 bits (1061), Expect = e-115
Identities = 225/442 (50%), Positives = 290/442 (65%), Gaps = 24/442 (5%)
Query: 1 MTSSYSSSSC-PLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGS 59
MTS SS+ C P C A G S ++ C PG A C + +R G
Sbjct: 1 MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCAT--SRCQTPSFLSRSRGLTG- 57
Query: 60 TPLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYL 119
CL P C G+C+ P +G C + +EKETMQFLNDRLA+YL
Sbjct: 58 --------CLLP-----CYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYL 104
Query: 120 EKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQI 179
EKVR LE+ NAELE+ + E+ + VCPDYQ YF+TIE+LQQKILC+KAEN+RL VQ+
Sbjct: 105 EKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQL 164
Query: 180 DNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLK 239
DN KLA DDF+ K ESE SLRQL+EAD +L++ TL K+DLEA ESLKE+ L LK
Sbjct: 165 DNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLK 224
Query: 240 SNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQS 299
NHE+EV +LR QLG++L +ELD PT+DLNRVL EMR Q E +L NR++ E+W Q+
Sbjct: 225 KNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQT 284
Query: 300 EGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTEL 359
E ++ Q +S +E+LQ CQ EILEL+ T +ALE+E QAQ +L + L+ ++ E E ++ ++L
Sbjct: 285 EELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQL 344
Query: 360 AQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNP 419
AQ+Q LI N+E QL+EIR DLERQNQEYQVLLDVK RLE EI TY LL+SED +L C+P
Sbjct: 345 AQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSP 404
Query: 420 CSTSPSCVTAPCAPRPSCGPCT 441
CST+ C +C PC+
Sbjct: 405 CSTT-------CTSSNTCEPCS 419
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 394 bits (1012), Expect = e-110
Identities = 232/458 (50%), Positives = 290/458 (63%), Gaps = 32/458 (6%)
Query: 6 SSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEA--NIAPMCLLANVAHANRVRVGSTPLG 63
+S S P C NVS + GC PG N P H R+ P
Sbjct: 10 NSPSTP--CQNCSRITNVSTISSNNGCHPGGLTVNNCQP------AGHVLRI-----PWD 56
Query: 64 RPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVR 123
+ P C L + ++ C YGE +N +EKETMQ LN+RLANYL+KVR
Sbjct: 57 QGCQPTPRFCRKPIYLMNNFNARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVR 115
Query: 124 QLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAK 183
LE+ENAELE+ + E S +CPDY SY+ TIEELQQKILC+KAEN+RL+ QIDN K
Sbjct: 116 MLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTK 175
Query: 184 LAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHE 243
L ADD R K E+E SLRQLVE+D G +++L+ TL KADLEAQ +SLKEE L LK+NH+
Sbjct: 176 LTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHK 235
Query: 244 QEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGIS 303
+E+ L+ QLGE+L IE+ P+ DLN+VL EMR QYE ++ETNR+DVEQWF Q E ++
Sbjct: 236 EEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELN 295
Query: 304 LQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQ 363
Q ++ S++ QCCQ EI+ELR +VN LEVE QAQH ++D + L E E R+ L Q+Q
Sbjct: 296 QQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQ 355
Query: 364 SLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNP---- 419
SLI N+E QL+EIR LERQNQEY++LLDVK+RLE EI TYR+LLES D K PC P
Sbjct: 356 SLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATK 415
Query: 420 CSTSP--SC------VTAP-CAPRPSCG---PCTTCGP 445
C SP SC TAP C C C+ CGP
Sbjct: 416 CEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSACGP 453
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 325 bits (832), Expect = 7e-89
Identities = 171/334 (51%), Positives = 236/334 (70%), Gaps = 6/334 (1%)
Query: 88 NIGICGAYG------ENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSK 141
+ G G YG + L G EK TMQ LNDRLA+YL+KVR LE+ N ELE + + +
Sbjct: 62 SFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQ 121
Query: 142 CHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQ 201
DY Y+ TIEELQ KIL + +NA +++QIDNA+LAADDFR K E+E++LR
Sbjct: 122 RQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRL 181
Query: 202 LVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIEL 261
VEAD G +++LD+ TLA+ADLE Q E+LKEE LK NHE+E+ LR Q+G ++ +E+
Sbjct: 182 SVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEM 241
Query: 262 DIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEIL 321
D P +DL+R+L EMR QYE M E NR+D E WF +++E ++ + + SE +Q +SEI
Sbjct: 242 DAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEIS 301
Query: 322 ELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLE 381
ELR T+ ALE+E Q+Q ++K L+ +L E E+R+ +L+Q+Q LI +VEEQL+++R ++E
Sbjct: 302 ELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEME 361
Query: 382 RQNQEYQVLLDVKTRLENEIATYRNLLESEDCKL 415
+QNQEY++LLDVKTRLE EIATYR LLE ED L
Sbjct: 362 QQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL 395
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 322 bits (826), Expect = 3e-88
Identities = 172/336 (51%), Positives = 236/336 (70%)
Query: 87 GNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHEST 146
G G A G+ L G EK TMQ LNDRLA+YL+KVR LE+ NA+LE + + +
Sbjct: 98 GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPA 157
Query: 147 VCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEAD 206
DY YF TIE+L+ KIL + +NA +++QIDNA+LAADDFR K E+E +LR VEAD
Sbjct: 158 EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEAD 217
Query: 207 KCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPT 266
G +++LD+ TLA+ADLE Q ESLKEE LK NHE+E+ LR Q+G + +E+D P
Sbjct: 218 INGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPG 277
Query: 267 IDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCT 326
+DL+R+L EMR QYE M E NR+D E+WF ++E ++ + + SE +Q +SEI ELR T
Sbjct: 278 VDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRT 337
Query: 327 VNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQE 386
+ LE+E Q+Q ++K L+NSL E + R+ +LAQ+Q +I +VEEQL+++R ++E+QNQE
Sbjct: 338 MQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQE 397
Query: 387 YQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCST 422
Y++LLDVKTRLE EIATYR LLE ED L + S+
Sbjct: 398 YKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSS 433
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 319 bits (818), Expect = 3e-87
Identities = 171/331 (51%), Positives = 237/331 (71%), Gaps = 6/331 (1%)
Query: 90 GICGAYGENT---LNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLE--RSKCHE 144
G G +G L+G+EK TMQ LNDRLA+YL+KVR LE+ NA+LE + + + +
Sbjct: 88 GFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPT 147
Query: 145 STVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVE 204
S C DY YF TIEEL+ KI+ + +N+R+I++IDNA+LAADDFR+K E+E +LRQ VE
Sbjct: 148 SPEC-DYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVE 206
Query: 205 ADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIE 264
AD G +++LD+ TLA+ DLE Q E L EE LK NHE+E+K SQL ++ +E+D
Sbjct: 207 ADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAA 266
Query: 265 PTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELR 324
P +DL RVL EMR QYEAM E NR+DVE WF +++E ++ + S +E +Q ++EI +LR
Sbjct: 267 PGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLR 326
Query: 325 CTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQN 384
T+ LE+E Q+Q ++K L+NSL E E R+ T+L Q+Q LI +E QLSE+R ++E QN
Sbjct: 327 RTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQN 386
Query: 385 QEYQVLLDVKTRLENEIATYRNLLESEDCKL 415
QEY++LLD+KTRLE EIATYR+LLE +D K+
Sbjct: 387 QEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 318 bits (814), Expect = 8e-87
Identities = 176/365 (48%), Positives = 243/365 (66%), Gaps = 3/365 (0%)
Query: 93 GAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCP--D 150
GA L G+EK TMQ LNDRLA+YLEKVR LE+ NA+LE + + +S P D
Sbjct: 93 GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWH-LKQSPASPERD 151
Query: 151 YQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGT 210
Y Y+ TIEEL+ KIL + EN R+I++IDNA+LAADDFR+K E+E +LRQ VEAD G
Sbjct: 152 YSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGL 211
Query: 211 QKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLN 270
+++LD+ TL+K DLE Q ESL EE +K NHE+E+K +Q+ ++ +E+D P IDL
Sbjct: 212 RRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLT 271
Query: 271 RVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNAL 330
RVL EMR QYEAM E NR+D E+WF A+S ++ + + + +Q ++EI ELR T+ L
Sbjct: 272 RVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGL 331
Query: 331 EVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVL 390
E+E Q+Q ++K L+N++ E E R+ +L Q+Q LIS++E QLSE+R+++E QNQEY++L
Sbjct: 332 EIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKML 391
Query: 391 LDVKTRLENEIATYRNLLESEDCKLPCNPCSTSPSCVTAPCAPRPSCGPCTTCGPTCGAS 450
LD+KTRLE EIATYR+LLE +D K+ P S + S TT G
Sbjct: 392 LDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRR 451
Query: 451 TTGSR 455
T+ R
Sbjct: 452 TSDVR 456
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 318 bits (814), Expect = 8e-87
Identities = 168/328 (51%), Positives = 229/328 (69%)
Query: 94 AYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQS 153
A G+ L G EK TMQ LNDRLA+YL+KVR LE+ NA+LE + + + + DY
Sbjct: 107 AGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSP 166
Query: 154 YFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKL 213
YF TIE+L+ KI+ + ENA+ I+QIDNA+LAADDFR K E E +LRQ VEAD G +++
Sbjct: 167 YFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRV 226
Query: 214 LDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVL 273
LD+ TLA+ DLE Q E LKEE L+ NHE+E+ LR Q G + +E+D P +DL+R+L
Sbjct: 227 LDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRIL 286
Query: 274 GEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVE 333
EMR QYE M E NR+D E WF +++E ++ + S SE +Q +SE+ ELR + LE+E
Sbjct: 287 NEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIE 346
Query: 334 RQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDV 393
Q+Q ++K L+NSL E + R+ +L+Q+Q LI +VEEQL+++R ++E+Q+QEYQ+LLDV
Sbjct: 347 LQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDV 406
Query: 394 KTRLENEIATYRNLLESEDCKLPCNPCS 421
KTRLE EIATYR LLE ED L S
Sbjct: 407 KTRLEQEIATYRRLLEGEDAHLSSQQAS 434
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 313 bits (803), Expect = 2e-85
Identities = 168/324 (51%), Positives = 232/324 (71%), Gaps = 3/324 (0%)
Query: 93 GAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCP--D 150
GA L G+EK TMQ LNDRLA+YLEKVR LE+ NA+LE + + +S P D
Sbjct: 93 GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWH-LKQSPASPERD 151
Query: 151 YQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGT 210
Y Y+ TIEEL+ KIL + EN R+I++IDNA+LAADDFR+K E+E +LRQ VEAD G
Sbjct: 152 YSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGL 211
Query: 211 QKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLN 270
+++LD+ TL+K DLE Q ESL EE +K NHE+E+K +Q+ ++ +E+D P IDL
Sbjct: 212 RRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLT 271
Query: 271 RVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNAL 330
RVL EMR QYEAM E NR+D E+WF A+S ++ + + + +Q ++EI ELR T+ L
Sbjct: 272 RVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGL 331
Query: 331 EVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVL 390
E+E Q+Q ++K L+N++ E E R+ +L Q+Q LIS++E QLSE+R+++E QNQEY++L
Sbjct: 332 EIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKML 391
Query: 391 LDVKTRLENEIATYRNLLESEDCK 414
LD+KTRLE EIATYR+LLE +D K
Sbjct: 392 LDIKTRLEQEIATYRSLLEGQDAK 415
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 311 bits (798), Expect = 6e-85
Identities = 161/326 (49%), Positives = 229/326 (70%), Gaps = 6/326 (1%)
Query: 93 GAYG------ENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHEST 146
G YG + L G+EK TMQ LNDRLA+YL+KVR LE N ELE + + +
Sbjct: 63 GGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPG 122
Query: 147 VCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEAD 206
DY Y+ TI++L+ KIL + EN+R+++QIDNA+LAADDFR K E+E++LR VEAD
Sbjct: 123 PSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEAD 182
Query: 207 KCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPT 266
G +++LD+ TLA+ DLE Q E LKEE LK NHE+E+ LR Q+G ++ +E+D P
Sbjct: 183 INGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPG 242
Query: 267 IDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCT 326
DL ++L +MR+QYE M E NR+D E WF +++E ++ + +E+LQ +SE+ +LR T
Sbjct: 243 TDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRT 302
Query: 327 VNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQE 386
+ LE+E Q+Q ++K L+++L E E RFG +LA +Q+LIS +E QL ++RAD ERQNQE
Sbjct: 303 LQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQE 362
Query: 387 YQVLLDVKTRLENEIATYRNLLESED 412
YQ L+D+K+RLE EIATYR+LLE ++
Sbjct: 363 YQRLMDIKSRLEQEIATYRSLLEGQE 388
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 291 bits (744), Expect = 1e-78
Identities = 161/327 (49%), Positives = 224/327 (68%), Gaps = 5/327 (1%)
Query: 90 GICGAYGEN--TLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHEST- 146
G G +G + L+G+EK TMQ LNDRLA+YL+KVR LE+ N ELE + E + H ++
Sbjct: 130 GFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSH 189
Query: 147 --VCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVE 204
DY Y+ TI++L+ +IL +NA +++QIDNA+LAADDFR+K E+E +LRQ VE
Sbjct: 190 QGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVE 249
Query: 205 ADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIE 264
AD G +++LD+ TL KADLE Q ESL EE LK NHE+E+K LR+ + +E++
Sbjct: 250 ADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAA 309
Query: 265 PTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELR 324
P +DL ++L MR+QYE + E NR+D E WF +S+ ++ + + E++ +SEI ELR
Sbjct: 310 PGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELR 369
Query: 325 CTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQN 384
V ALE+E Q+Q LK L+ SL E E R+ +L+Q+Q+ IS +EEQL +IRA+ E QN
Sbjct: 370 RNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQN 429
Query: 385 QEYQVLLDVKTRLENEIATYRNLLESE 411
EYQ LLD+K RLENEI TYR+LLE E
Sbjct: 430 TEYQQLLDIKIRLENEIQTYRSLLEGE 456
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 281 bits (719), Expect = 9e-76
Identities = 155/329 (47%), Positives = 217/329 (65%), Gaps = 4/329 (1%)
Query: 87 GNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLE----RSKC 142
G++GI L+G EKETMQ LNDRLA+YL+KVR LE+ N ELE + E R
Sbjct: 108 GSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTG 167
Query: 143 HESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQL 202
DY Y+ IE+L+ KI+ + NA+L++QIDNA+LAA+DFR+K E+E +LRQ
Sbjct: 168 TADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQG 227
Query: 203 VEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELD 262
VEAD G +++LD+ TL + DLE Q ESL EE +K NHE E++ R ++ +E+D
Sbjct: 228 VEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMD 287
Query: 263 IEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILE 322
P +DL R+L +MRAQYE + E NR+D E WF +S + + + +E+LQ +SE+ +
Sbjct: 288 AAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTD 347
Query: 323 LRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLER 382
LR LE+E Q+Q +K L++SL EAE + +L+Q+Q LISN+E QL ++RAD ER
Sbjct: 348 LRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAER 407
Query: 383 QNQEYQVLLDVKTRLENEIATYRNLLESE 411
QN ++Q LL+VK RLE EI TYR LL+ E
Sbjct: 408 QNVDHQRLLNVKARLELEIETYRRLLDGE 436
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 278 bits (711), Expect = 7e-75
Identities = 145/319 (45%), Positives = 215/319 (67%)
Query: 96 GENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYF 155
G + G+EK MQ LNDRLA+YLEKVR LEQ N++LE + + + + DY +Y+
Sbjct: 62 GGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYY 121
Query: 156 HTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLD 215
IEEL+ +I ++ +NAR ++QIDNAKLAA+DFR+K E+ER +R VEAD G K+ D
Sbjct: 122 RQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFD 181
Query: 216 DATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGE 275
D TL K DLE Q E L ++ LK H++EV L LG + +E+D P ++L ++ E
Sbjct: 182 DLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNE 241
Query: 276 MRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQ 335
MR +YE M + N Q+ ++ F+ Q+ + Q +EEL+ + ++ ELR T +LE+E Q
Sbjct: 242 MRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQ 301
Query: 336 AQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKT 395
+ ++K+ L+++L E + R+ ++LA +QSL+S++E QL +IR+++ERQN EY +LLD+KT
Sbjct: 302 SHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKT 361
Query: 396 RLENEIATYRNLLESEDCK 414
RLE EIATYR LLE ED K
Sbjct: 362 RLEQEIATYRRLLEGEDVK 380
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 263 bits (671), Expect = 3e-70
Identities = 152/354 (42%), Positives = 211/354 (59%), Gaps = 14/354 (3%)
Query: 79 LPGTCHIPGNIGICGAYG-----ENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELE 133
+PG H G +G G L+G+EK TMQ LNDRLA+YL+ VR LE+ NAELE
Sbjct: 56 VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELE 115
Query: 134 ATLLERSKCHESTVCP----DYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDF 189
+ + + C DY Y TIE+L+ KI+ S NA +I+QIDNA+LAADDF
Sbjct: 116 RKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDF 175
Query: 190 RIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKIL 249
R+K E+E +L Q VEAD G +++LD+ TL + D E Q ESL EE LK NHE+E+K L
Sbjct: 176 RLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKAL 235
Query: 250 RSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSC 309
+ G + +E++ P +DL +L MRA+YEA+ E NR+D E WF +S + Q
Sbjct: 236 QCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHD 295
Query: 310 SEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNV 369
S +S++ E+R T+ LE++ Q+ K L+ SL E E + T+LAQ+Q+ I +
Sbjct: 296 SGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGAL 355
Query: 370 EEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTS 423
EEQL ++R + E Q EY+ LLDVK LE EI TY L++ + N CS S
Sbjct: 356 EEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCSKS 404
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 259 bits (662), Expect = 4e-69
Identities = 142/328 (43%), Positives = 213/328 (64%), Gaps = 6/328 (1%)
Query: 90 GICGAYGENTL-NGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCH----- 143
G+ G G+ L +G EK+TMQ LNDRLANYL+KVR LE+ N +LE + E +
Sbjct: 125 GMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSG 184
Query: 144 ESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLV 203
+ DY Y+ IE+L+ +I+ + ENA +I+ IDNA+LAADDFR+K E+E LRQ V
Sbjct: 185 DGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSV 244
Query: 204 EADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDI 263
EAD G +K+LDD T+ ++DLE Q ES EE L+ NHE+E+K ++ G ++ +E++
Sbjct: 245 EADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNA 304
Query: 264 EPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILEL 323
P DL ++L +MRAQYE + E NR++ E+ F QS + Q + + ++EI EL
Sbjct: 305 APGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITEL 364
Query: 324 RCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQ 383
+ T+ ALE+E Q+Q +K L+ +L + E + +L+++Q+ IS +EE++ +I + + Q
Sbjct: 365 KRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQ 424
Query: 384 NQEYQVLLDVKTRLENEIATYRNLLESE 411
N EY+ LLD+KTRLE EI TYR LL+ E
Sbjct: 425 NAEYKQLLDIKTRLEVEIETYRRLLDGE 452
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 254 bits (648), Expect = 1e-67
Identities = 140/333 (42%), Positives = 203/333 (60%), Gaps = 7/333 (2%)
Query: 87 GNIGICGAYGENT---LNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCH 143
G C A+ N L+G+EK TMQ LNDRLA+YLE VR LE+ NA+LE + +
Sbjct: 64 GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKF 123
Query: 144 ESTVCP----DYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSL 199
C DY YF I+EL+ +I+ + NA +++Q DNA+L ADDFR+K E+E +L
Sbjct: 124 GPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183
Query: 200 RQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRI 259
Q VEAD G +++LD+ TL + DLE Q E+L EE LK NHE+E+K L+ G + +
Sbjct: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNV 243
Query: 260 ELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSE 319
E++ P +DL +L MRA+YEA+ E NR+D E WF +S + Q + ++E
Sbjct: 244 EMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNE 303
Query: 320 ILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRAD 379
++E++ T+ LE+E Q+ K L+ SL E E + +LAQ+Q+ I +EEQL ++R +
Sbjct: 304 LIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTE 363
Query: 380 LERQNQEYQVLLDVKTRLENEIATYRNLLESED 412
E Q EY+ LLD+K LE EI TY L++ ED
Sbjct: 364 TEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 250 bits (639), Expect = 2e-66
Identities = 133/315 (42%), Positives = 211/315 (66%), Gaps = 3/315 (0%)
Query: 103 HEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQ 162
+EKETMQ LNDRLA+YL++VR LE EN LE+ + E + V D+ YF IE+L+
Sbjct: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
Query: 163 QKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKA 222
+I + +NAR+++QIDNA+LAADDFR+K E+E ++RQ VE D G +K++DD + +
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
Query: 223 DLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEK-LRIELDIEPTIDLNRVLGEMRAQYE 281
LE + E+LKEE L +K NHE+EVK L++Q+ L +E+D + DL +++ ++RAQY+
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
Query: 282 AMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLK 341
+ NR+++++++ Q E + + S E+ ++ + ELR TV +LE++ + LK
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
Query: 342 DCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEI 401
L+NSL E E R+ ++ Q+ ++ ++E +L++ RA+ +RQ QEY+ LL++K +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
Query: 402 ATYRNLLE-SEDCKL 415
ATYR LLE ED L
Sbjct: 378 ATYRRLLEDGEDFNL 392
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 250 bits (639), Expect = 2e-66
Identities = 133/315 (42%), Positives = 211/315 (66%), Gaps = 3/315 (0%)
Query: 103 HEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQ 162
+EKETMQ LNDRLA+YL++VR LE EN LE+ + E + V D+ YF IE+L+
Sbjct: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
Query: 163 QKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKA 222
+I + +NAR+++QIDNA+LAADDFR+K E+E ++RQ VE D G +K++DD + +
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
Query: 223 DLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEK-LRIELDIEPTIDLNRVLGEMRAQYE 281
LE + E+LKEE L +K NHE+EVK L++Q+ L +E+D + DL +++ ++RAQY+
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
Query: 282 AMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLK 341
+ NR+++++++ Q E + + S E+ ++ + ELR TV +LE++ + LK
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
Query: 342 DCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEI 401
L+NSL E E R+ ++ Q+ ++ ++E +L++ RA+ +RQ QEY+ LL++K +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
Query: 402 ATYRNLLE-SEDCKL 415
ATYR LLE ED L
Sbjct: 378 ATYRRLLEDGEDFNL 392
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 246 bits (628), Expect = 3e-65
Identities = 134/340 (39%), Positives = 210/340 (61%), Gaps = 16/340 (4%)
Query: 76 ACPLPGTCHIPGNIGICGAYGENT----LNGHEKETMQFLNDRLANYLEKVRQLEQENAE 131
+CP PG G++G L G+ K TMQ LNDRLA+YLEKVR LE+ N +
Sbjct: 51 SCPPPG-----------GSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMK 99
Query: 132 LEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRI 191
LE+ +L+ + + DY Y I LQ++I+ K NA++I+ IDNA++A DDF +
Sbjct: 100 LESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNL 159
Query: 192 KLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRS 251
K E+E S ++ +E + G ++ LD+ T+ DLE + E +++E + +K +HEQE++
Sbjct: 160 KYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHV 219
Query: 252 QLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSE 311
+ +++D P DL +VL +MR +YE +++ +D++ W++ QS +S Q+ +
Sbjct: 220 PSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMS-QEAASPA 278
Query: 312 ELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEE 371
+Q Q +I EL+ T ALE++ Q Q++ K L+N L E + R+ +L MQ +IS+ EE
Sbjct: 279 TVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEE 338
Query: 372 QLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESE 411
+L+++R +LERQN EYQVLL +KT LE EI TYR LLE E
Sbjct: 339 ELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGE 378
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 246 bits (627), Expect = 4e-65
Identities = 134/321 (41%), Positives = 197/321 (61%), Gaps = 6/321 (1%)
Query: 100 LNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCP----DYQSYF 155
L+G+EK TMQ LNDRLA+YL+ V LE+ NA+LE + + C DY YF
Sbjct: 75 LSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYF 134
Query: 156 HTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLD 215
I++L+ +I+ S NA ++QIDNA+L ADDFR+K E+E +L Q VEAD G +++LD
Sbjct: 135 PIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLD 194
Query: 216 DATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGE 275
+ TL + DLE Q E+L EE LK NH++E+++L+ G + +E++ P +DL +L
Sbjct: 195 EITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNN 254
Query: 276 MRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQ 335
MRA+YEA+ E NR+D E WF +S + Q ++E+ E++ T+ LE+E Q
Sbjct: 255 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQ 314
Query: 336 AQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKT 395
+ K L+ SL E E + +LAQ+Q+ I +EEQL ++R + E Q EY+ LLD+K
Sbjct: 315 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKL 374
Query: 396 RLENEIATYRNLLESED--CK 414
LE EI TY L+ +D CK
Sbjct: 375 HLEKEIETYCLLIGGDDGACK 395
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 240 bits (613), Expect = 2e-63
Identities = 127/321 (39%), Positives = 204/321 (63%), Gaps = 1/321 (0%)
Query: 90 GICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLE-RSKCHESTVC 148
G G L +EK TMQ LN RLA+YL+KV+ LE+ N +LE + + K + +
Sbjct: 139 GGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQ 198
Query: 149 PDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKC 208
+Y Y++TI++L+ +I+ N + ++ IDN ++ DDFRIK E E++LRQ V+AD
Sbjct: 199 KNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADIN 258
Query: 209 GTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTID 268
G +++LD+ T+ K+DLE Q E+L+EE ++LK NH++E+ L Q + +E+++ P D
Sbjct: 259 GLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKD 318
Query: 269 LNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVN 328
L + L +MR +YE ++ NR+D+E ++ Q I + S +E+Q E+ +LR V
Sbjct: 319 LTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQ 378
Query: 329 ALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQ 388
LE+E Q+Q + K L+ SL + ++R+ +L +Q ISN+E Q++++R ++E QNQEY
Sbjct: 379 ELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYS 438
Query: 389 VLLDVKTRLENEIATYRNLLE 409
+LL +K RLE EI TY NLLE
Sbjct: 439 LLLSIKMRLEKEIETYHNLLE 459
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 239 bits (609), Expect = 5e-63
Identities = 144/380 (37%), Positives = 214/380 (56%), Gaps = 17/380 (4%)
Query: 52 ANRVRVGSTPLGRPSLCLPPTCHTA--CPLPGT------CHIPGNIGICGAYG-----EN 98
+ R+ G T ++C+ ++ C L G C+ G +G G +
Sbjct: 18 SGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHS 77
Query: 99 TLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLER-SKCHESTVCP---DYQSY 154
L+G+EK TMQ LNDRLA+YL+ V LE+ NA+LE + R KC + DY Y
Sbjct: 78 LLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRY 137
Query: 155 FHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLL 214
F IE+L+++I + NA +++Q DNA+L ADDFR+K E+E +L VEAD G +++L
Sbjct: 138 FSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVL 197
Query: 215 DDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLG 274
D+ TL DLE Q E+L EE LK +HE+E+++L+ G + +E++ P +DL +L
Sbjct: 198 DELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLN 257
Query: 275 EMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVER 334
MRA+YE + E NR+D E WF +S + Q ++E+ EL+ + LE+E
Sbjct: 258 NMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIEL 317
Query: 335 QAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVK 394
Q+ +K + SL E E + +L Q+Q I +EEQL +IR + E Q EY+ LLDVK
Sbjct: 318 QSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVK 377
Query: 395 TRLENEIATYRNLLESEDCK 414
LE EI Y NLL+ E+ K
Sbjct: 378 IFLEKEIDIYCNLLDGEERK 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,575,642
Number of Sequences: 37866
Number of extensions: 837500
Number of successful extensions: 7924
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 179
Number of HSP's successfully gapped in prelim test: 556
Number of HSP's that attempted gapping in prelim test: 5426
Number of HSP's gapped (non-prelim): 2387
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.