Search of human proteins with 15431310

Search of human proteins with 15431310

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15431310 keratin 14 [Homo sapiens]
         (472 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15431310 keratin 14 [Homo sapiens]                                 920   0.0  
gi|24430192 keratin 16 [Homo sapiens]                                 768   0.0  
gi|4557701 keratin 17 [Homo sapiens]                                  639   0.0  
gi|24430190 keratin 15 [Homo sapiens]                                 559   e-159
gi|131412225 keratin 13 isoform a [Homo sapiens]                      547   e-156
gi|131412228 keratin 13 isoform b [Homo sapiens]                      539   e-153
gi|195972866 keratin 10 [Homo sapiens]                                493   e-139
gi|24234699 keratin 19 [Homo sapiens]                                 484   e-137
gi|4557699 keratin 12 [Homo sapiens]                                  468   e-132
gi|192807292 keratin 24 [Homo sapiens]                                444   e-125
gi|4504927 keratin 36 [Homo sapiens]                                  444   e-125
gi|55956899 keratin 9 [Homo sapiens]                                  436   e-122
gi|153945736 keratin 27 [Homo sapiens]                                427   e-119
gi|114431246 keratin 25D [Homo sapiens]                               421   e-117
gi|94538345 keratin 35 [Homo sapiens]                                 411   e-115
gi|31559829 keratin 25 [Homo sapiens]                                 403   e-112
gi|27894337 keratin 20 [Homo sapiens]                                 394   e-109
gi|14917115 keratin 31 [Homo sapiens]                                 382   e-106
gi|14917117 keratin 33A [Homo sapiens]                                380   e-105
gi|31559815 keratin 26 [Homo sapiens]                                 378   e-105
gi|10337581 type I hair keratin 3B [Homo sapiens]                     377   e-104
gi|116488398 keratin 32 [Homo sapiens]                                373   e-103
gi|14917119 keratin 34 [Homo sapiens]                                 371   e-103
gi|40354195 keratin 18 [Homo sapiens]                                 351   9e-97
gi|4557888 keratin 18 [Homo sapiens]                                  351   9e-97
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  343   3e-94
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  326   3e-89
gi|15431318 keratin 38 [Homo sapiens]                                 322   4e-88
gi|55770882 keratin 37 [Homo sapiens]                                 316   3e-86
gi|27894339 keratin 23 [Homo sapiens]                                 311   1e-84

>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  920 bits (2377), Expect = 0.0
 Identities = 472/472 (100%), Positives = 472/472 (100%)

Query: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSG 60
           MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSG
Sbjct: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSG 60

Query: 61  GAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQ 120
           GAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQ
Sbjct: 61  GAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQ 120

Query: 121 NLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTAT 180
           NLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTAT
Sbjct: 121 NLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTAT 180

Query: 181 VDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIE 240
           VDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIE
Sbjct: 181 VDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIE 240

Query: 241 SLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK 300
           SLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK
Sbjct: 241 SLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK 300

Query: 301 DAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLE 360
           DAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLE
Sbjct: 301 DAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLE 360

Query: 361 ETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE 420
           ETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE
Sbjct: 361 ETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE 420

Query: 421 GEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQVLRTKN 472
           GEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQVLRTKN
Sbjct: 421 GEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQVLRTKN 472


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  768 bits (1984), Expect = 0.0
 Identities = 400/458 (87%), Positives = 423/458 (92%), Gaps = 11/458 (2%)

Query: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSG 60
           MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSS RFSSG
Sbjct: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSS-RFSSG 59

Query: 61  GAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGG----FGGGFAGGDGLLVGSEK 116
           GA GLGGGYGGGFSSSSS FGSGFGGGYGGGLGAG GGG    FGGGFAGGDGLLVGSEK
Sbjct: 60  GACGLGGGYGGGFSSSSS-FGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEK 118

Query: 117 VTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKI 176
           VTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRP+EIKDYSPYFKTIEDLRNKI
Sbjct: 119 VTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKI 178

Query: 177 LTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLE 236
           + AT++NA  +LQIDNARLAADDFRTKYE EL LR +VEAD+NGLRRVLDELTLAR DLE
Sbjct: 179 IAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLE 238

Query: 237 MQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAE 296
           MQIE LKEELAYL+KNHEEEM ALRGQ GGDVNVEMDAAPGVDLSRILNEMRDQYE+MAE
Sbjct: 239 MQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAE 298

Query: 297 KNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLE 356
           KNR+DAE WF +KTEELN+EVA+NSELVQS +SE++ELRR +Q LEIELQSQLSMKASLE
Sbjct: 299 KNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLE 358

Query: 357 NSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYR 416
           NSLEETKGRYCMQL+QIQ +IGSVEEQLAQLRCEMEQQ+QEY+ILLDVKTRLEQEIATYR
Sbjct: 359 NSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYR 418

Query: 417 RLLEGEDAHLSSSQFSSGSQSSRDV-----TSSSRQIR 449
           RLLEGEDAHLSS Q S  S SSR+V     +SSSRQ R
Sbjct: 419 RLLEGEDAHLSSQQASGQSYSSREVFTSSSSSSSRQTR 456


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  639 bits (1647), Expect = 0.0
 Identities = 346/470 (73%), Positives = 376/470 (80%), Gaps = 40/470 (8%)

Query: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSG 60
           MTT  RQFTSSSS+KGS G+GGG    S R+S  L  GSCR                  G
Sbjct: 1   MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL-----------------G 43

Query: 61  GAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQ 120
            A GLG   GG   SS  SFGSG              GG+G  F G DGLL G EK TMQ
Sbjct: 44  SAGGLGSTLGGSSYSSCYSFGSG--------------GGYGSSFGGVDGLLAGGEKATMQ 89

Query: 121 NLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTAT 180
           NLNDRLASYLDKVRALEEAN +LEVKIRDWYQRQ P   +DYS Y++TIE+L+NKILTAT
Sbjct: 90  NLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTAT 149

Query: 181 VDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIE 240
           VDNAN+LLQIDNARLAADDFRTK+ETE  LR+SVEADINGLRRVLDELTLARADLEMQIE
Sbjct: 150 VDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIE 209

Query: 241 SLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK 300
           +LKEELAYLKKNHEEEMNALRGQVGG++NVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK
Sbjct: 210 NLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRK 269

Query: 301 DAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLE 360
           DAE+WFF+KTEELNREVATNSELVQSGKSEISELRRTMQ LEIELQSQLSMKASLE +L 
Sbjct: 270 DAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLA 329

Query: 361 ETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE 420
           ET+ RYC+QL+QIQ +IGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE
Sbjct: 330 ETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE 389

Query: 421 GEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQVLRT 470
           GEDAHL+             VT  +RQ+RT V +V DGKV+S+ EQV +T
Sbjct: 390 GEDAHLT-------QYKKEPVT--TRQVRTIVEEVQDGKVISSREQVHQT 430


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  559 bits (1441), Expect = e-159
 Identities = 302/473 (63%), Positives = 353/473 (74%), Gaps = 26/473 (5%)

Query: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGG-----LSVSSS 55
           MTT   Q +SS+            GGGS+R  S+LAGG      +  GG     +S SS+
Sbjct: 1   MTTTFLQTSSST-----------FGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSA 49

Query: 56  RFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDG-LLVGS 114
           RF S G+   GGGYGGG       FG G G  +GGG G G+GGGFGGGF GGDG LL G+
Sbjct: 50  RFVSSGS---GGGYGGGMRVCG--FGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGN 104

Query: 115 EKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIK-DYSPYFKTIEDLR 173
           EK+TMQNLNDRLASYLDKVRALEEANADLEVKI DWYQ+Q P   + DYS YFKTIE+LR
Sbjct: 105 EKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELR 164

Query: 174 NKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARA 233
           +KI+  T+DN+ V+L+IDNARLAADDFR KYE EL LR  VEADINGLRRVLDELTLAR 
Sbjct: 165 DKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLART 224

Query: 234 DLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEK 293
           DLEMQIE L EELAYLKKNHEEEM     Q+ G VNVEMDAAPGVDL+R+L EMR+QYE 
Sbjct: 225 DLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEA 284

Query: 294 MAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKA 353
           MAEKNR+D E WFF+KTEELN+EVA+N+E++Q+ K+EI++LRRTMQ LEIELQSQLSMKA
Sbjct: 285 MAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKA 344

Query: 354 SLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIA 413
            LENSL ET+ RY  QL QIQ +IG +E QL++LRCEME QNQEYK+LLD+KTRLEQEIA
Sbjct: 345 GLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIA 404

Query: 414 TYRRLLEGEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQ 466
           TYR LLEG+DA ++       S        SS      V +  DG+VVS+H++
Sbjct: 405 TYRSLLEGQDAKMAGIGIREASSGG---GGSSSNFHINVEESVDGQVVSSHKR 454


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  547 bits (1410), Expect = e-156
 Identities = 292/451 (64%), Positives = 346/451 (76%), Gaps = 33/451 (7%)

Query: 17  SCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFS-- 74
           S   GGG GGGS ++     GG        G G+S  S+RF SGG+    GGYGGG S  
Sbjct: 9   SASYGGGFGGGSCQL-----GG--------GRGVSTCSTRFVSGGS---AGGYGGGVSCG 52

Query: 75  ---SSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGG--------DGLLVGSEKVTMQNLN 123
               + S FG G+GGG GGG G GLGGGFGGGFAGG         GLL G+EK+TMQNLN
Sbjct: 53  FGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLN 112

Query: 124 DRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEI-KDYSPYFKTIEDLRNKILTATVD 182
           DRLASYL+KVRALEEANADLEVKIRDW+ +Q PA   +DYSPY+KTIE+LR+KILTAT++
Sbjct: 113 DRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIE 172

Query: 183 NANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESL 242
           N  V+L+IDNARLAADDFR KYE EL LR SVEADINGLRRVLDELTL++ DLEMQIESL
Sbjct: 173 NNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESL 232

Query: 243 KEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDA 302
            EELAY+KKNHEEEM     QV G VNVEMDA PG+DL+R+L EMR+QYE MAE+NR+DA
Sbjct: 233 NEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDA 292

Query: 303 EEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEET 362
           EEWF  K+ ELN+EV+TN+ ++Q+ K+EI+ELRRT+Q LEIELQSQLSMKA LEN++ ET
Sbjct: 293 EEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAET 352

Query: 363 KGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE 422
           + RY +QL QIQ +I S+E QL++LR EME QNQEYK+LLD+KTRLEQEIATYR LLEG+
Sbjct: 353 ECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQ 412

Query: 423 DAHLSSSQFSSGSQSSRD---VTSSSRQIRT 450
           DA +     S+GS S R     T+SS  + T
Sbjct: 413 DAKMIGFPSSAGSVSPRSTSVTTTSSASVTT 443


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  539 bits (1389), Expect = e-153
 Identities = 283/422 (67%), Positives = 333/422 (78%), Gaps = 30/422 (7%)

Query: 17  SCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFS-- 74
           S   GGG GGGS ++     GG        G G+S  S+RF SGG+    GGYGGG S  
Sbjct: 9   SASYGGGFGGGSCQL-----GG--------GRGVSTCSTRFVSGGS---AGGYGGGVSCG 52

Query: 75  ---SSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGG--------DGLLVGSEKVTMQNLN 123
               + S FG G+GGG GGG G GLGGGFGGGFAGG         GLL G+EK+TMQNLN
Sbjct: 53  FGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLN 112

Query: 124 DRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEI-KDYSPYFKTIEDLRNKILTATVD 182
           DRLASYL+KVRALEEANADLEVKIRDW+ +Q PA   +DYSPY+KTIE+LR+KILTAT++
Sbjct: 113 DRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIE 172

Query: 183 NANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESL 242
           N  V+L+IDNARLAADDFR KYE EL LR SVEADINGLRRVLDELTL++ DLEMQIESL
Sbjct: 173 NNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESL 232

Query: 243 KEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDA 302
            EELAY+KKNHEEEM     QV G VNVEMDA PG+DL+R+L EMR+QYE MAE+NR+DA
Sbjct: 233 NEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDA 292

Query: 303 EEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEET 362
           EEWF  K+ ELN+EV+TN+ ++Q+ K+EI+ELRRT+Q LEIELQSQLSMKA LEN++ ET
Sbjct: 293 EEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAET 352

Query: 363 KGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE 422
           + RY +QL QIQ +I S+E QL++LR EME QNQEYK+LLD+KTRLEQEIATYR LLEG+
Sbjct: 353 ECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQ 412

Query: 423 DA 424
           DA
Sbjct: 413 DA 414


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  493 bits (1269), Expect = e-139
 Identities = 277/445 (62%), Positives = 318/445 (71%), Gaps = 33/445 (7%)

Query: 11  SSSMKGSCGIGGGIGGG----SSRISSVLA--GGSCRAPSTYGGGLSVSSSRF-----SS 59
           SSS  G  G GGG GGG    S RISS     GG   +    GG  S  SS       SS
Sbjct: 12  SSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSS 71

Query: 60  GGAYGLGGGYGGGFSSS--SSSFGSGFGGGYGGGL-----------------GAGLGGGF 100
           GG  GLGG  GG F  S  SSSFG  +GG +GGG                  G G GGGF
Sbjct: 72  GGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGF 131

Query: 101 GGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQ---RPA 157
           GGGF G  GLL G+EKVTMQNLNDRLASYLDKVRALEE+N +LE KI++WY++       
Sbjct: 132 GGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQG 191

Query: 158 EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEAD 217
           E +DYS Y+KTI+DL+N+IL  T DNAN+LLQIDNARLAADDFR KYE E+ LR SVEAD
Sbjct: 192 EPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEAD 251

Query: 218 INGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPG 277
           INGLRRVLDELTL +ADLEMQIESL EELAYLKKNHEEEM  LR    GDVNVEM+AAPG
Sbjct: 252 INGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPG 311

Query: 278 VDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRT 337
           VDL+++LN MR QYE++AE+NRKDAE WF  K++EL  E+  N E + S KSEI+ELRR 
Sbjct: 312 VDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRN 371

Query: 338 MQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQE 397
           +Q LEIELQSQL++K SLE SL ET+GRYC+QL+QIQ  I ++EEQL Q+R E E QN E
Sbjct: 372 VQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTE 431

Query: 398 YKILLDVKTRLEQEIATYRRLLEGE 422
           Y+ LLD+K RLE EI TYR LLEGE
Sbjct: 432 YQQLLDIKIRLENEIQTYRSLLEGE 456



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 47/102 (46%), Positives = 54/102 (52%), Gaps = 13/102 (12%)

Query: 9   TSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYG---L 65
           +S    +G    GGG GGGSS       GGS  +   +GGG   SS     GG+ G    
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSS------GGGS--SGGGHGGGHGGSSGGGYGGGSSGGGSS 509

Query: 66  GGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGG 107
           GGGYGGG  SSS   G    GGYGGG   G GGG+GGG +GG
Sbjct: 510 GGGYGGG--SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGG 549



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 39/77 (50%), Positives = 42/77 (54%), Gaps = 10/77 (12%)

Query: 21  GGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLG--GGYGGGFSSSSS 78
           GGG GGGSS       GGS  +   YGGG S      SS G YG G  GG GGG+   SS
Sbjct: 496 GGGYGGGSS------GGGS--SGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSS 547

Query: 79  SFGSGFGGGYGGGLGAG 95
             GS  GGGYGGG  +G
Sbjct: 548 GGGSSSGGGYGGGSSSG 564



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 32/60 (53%), Positives = 34/60 (56%), Gaps = 4/60 (6%)

Query: 58  SSGGAYG---LGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGS 114
           S GG  G    GGGYGGG S   SS G G GGG+GG  G G GGG  GG + G G   GS
Sbjct: 459 SGGGGRGGGSFGGGYGGGSSGGGSS-GGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS 517



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 21/42 (50%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 70  GGGFSSSSSSFGSGFGGGYGGGL--GAGLGGGFGGGFAGGDG 109
           G G S      G  FGGGYGGG   G   GGG GGG  G  G
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSG 496



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/70 (47%), Positives = 33/70 (47%), Gaps = 10/70 (14%)

Query: 16  GSCGIGGGIGGGSSR------ISSVLAGGSCRAPST-YGGGLSVSSSRFSSGGAYGLGGG 68
           G    GGG GGGSS        S    GGS       YGGG S   S  SSGG YG GG 
Sbjct: 505 GGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGS--SSGGGYG-GGS 561

Query: 69  YGGGFSSSSS 78
             GG  SSSS
Sbjct: 562 SSGGHKSSSS 571



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 3/44 (6%)

Query: 69  YGGGFSSSSSSFGSGFGGG-YGGGLGAGL--GGGFGGGFAGGDG 109
           Y        SS G G GGG +GGG G G   GG  GGG  GG G
Sbjct: 449 YRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHG 492



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 30/73 (41%), Positives = 30/73 (41%), Gaps = 25/73 (34%)

Query: 16  GSCGIGGGI-GGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFS 74
           GS G GGG  GGGSS                 GGG        SSGG YG G   GG  S
Sbjct: 533 GSSGGGGGGYGGGSS-----------------GGG-------SSSGGGYGGGSSSGGHKS 568

Query: 75  SSSSSFGSGFGGG 87
           SSS S G     G
Sbjct: 569 SSSGSVGESSSKG 581


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  484 bits (1246), Expect = e-137
 Identities = 263/433 (60%), Positives = 327/433 (75%), Gaps = 45/433 (10%)

Query: 1   MTTCS-RQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGG----GLSVSSS 55
           MT+ S RQ +++SS        GG+GGGS R      G + RAPS +GG    G+SVSS+
Sbjct: 1   MTSYSYRQSSATSSF-------GGLGGGSVRFGP---GVAFRAPSIHGGSGGRGVSVSSA 50

Query: 56  RFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSE 115
           RF S              SSSS ++G                GG+GG     DGLL G+E
Sbjct: 51  RFVS--------------SSSSGAYG----------------GGYGGVLTASDGLLAGNE 80

Query: 116 KVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNK 175
           K+TMQNLNDRLASYLDKVRALE AN +LEVKIRDWYQ+Q P   +DYS Y+ TI+DLR+K
Sbjct: 81  KLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDK 140

Query: 176 ILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADL 235
           IL AT++N+ ++LQIDNARLAADDFRTK+ETE  LRMSVEADINGLRRVLDELTLAR DL
Sbjct: 141 ILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDL 200

Query: 236 EMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMA 295
           EMQIE LKEELAYLKKNHEEE++ LRGQVGG V+VE+D+APG DL++IL++MR QYE MA
Sbjct: 201 EMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMA 260

Query: 296 EKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASL 355
           E+NRKDAE WF ++TEELNREVA ++E +Q  +SE+++LRRT+Q LEIELQSQLSMKA+L
Sbjct: 261 EQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAAL 320

Query: 356 ENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATY 415
           E++L ET+ R+  QLA IQ +I  +E QL  +R + E+QNQEY+ L+D+K+RLEQEIATY
Sbjct: 321 EDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATY 380

Query: 416 RRLLEGEDAHLSS 428
           R LLEG++ H ++
Sbjct: 381 RSLLEGQEDHYNN 393


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  468 bits (1205), Expect = e-132
 Identities = 261/462 (56%), Positives = 326/462 (70%), Gaps = 23/462 (4%)

Query: 27  GSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSS-SSSFGSGFG 85
           G  R  S  + GS    S +G G S     FS+   +G   G+GGG  SS +   G+G+G
Sbjct: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGG-FSAASMFGSSSGFGGGSGSSMAGGLGAGYG 86

Query: 86  GGYGGGLGAGLGGGFGGGFAGGD---------GLLVGSEKVTMQNLNDRLASYLDKVRAL 136
              GGG   GLG GFGG   GG          GLL GSEK TMQNLNDRLASYLDKVRAL
Sbjct: 87  RALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRAL 146

Query: 137 EEANADLEVKIRDWYQRQ----RPAEIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDN 192
           EEAN +LE KIR+WY+ +      A   DYS Y+  IEDLRNKI++A++ NA +LLQIDN
Sbjct: 147 EEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDN 206

Query: 193 ARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKN 252
           ARLAA+DFR KYE EL LR  VEADINGLRRVLDELTL R DLEMQIESL EELAY+KKN
Sbjct: 207 ARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKN 266

Query: 253 HEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEE 312
           HE+E+ + R    G+V+VEMDAAPGVDL+R+LN+MR QYE +AE+NRKDAE WF  K+ E
Sbjct: 267 HEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGE 326

Query: 313 LNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQ 372
           L +E++TN+E +QS KSE+++LRR  QNLEIELQSQL+MK SLE+SL E +G YC QL+Q
Sbjct: 327 LRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQ 386

Query: 373 IQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE--DAHLSSSQ 430
           +Q++I ++E QL Q+R + E+QN +++ LL+VK RLE EI TYRRLL+GE     L  S 
Sbjct: 387 VQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESL 446

Query: 431 FSSGSQSSRDVTSSS------RQIRTKVMDVHDGKVVSTHEQ 466
           F + S+S    T SS      R+I+T V ++ +G+VVS+  Q
Sbjct: 447 FVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQ 488


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  444 bits (1143), Expect = e-125
 Identities = 263/497 (52%), Positives = 335/497 (67%), Gaps = 50/497 (10%)

Query: 10  SSSSMKGSCGIGG----GIGGGSSRISSVLAGGSCRA-PSTYGGGLSVSSSRFSSGGAYG 64
           SS S    CG+GG    G  GG+S  S  L+GGS  A   ++GGG    S     GGA G
Sbjct: 25  SSFSSGSRCGLGGSSAQGFRGGASSCS--LSGGSSGAFGGSFGGGFGSCSVGGGFGGASG 82

Query: 65  LGGGYGGGFSSSSSSFG--SGFGGGYG----GGLGAGLGGGF---GGGFAGG---DGLLV 112
            G G+GGG     SSFG  SGFG G G        +G  GGF   GGG  GG    GL  
Sbjct: 83  SGTGFGGG-----SSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFS 137

Query: 113 GSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEI-----KDYSPYFK 167
           G EK TMQNLNDRLA+YLDKVRALEEAN DLE KI++WY +  P        +DYS Y+ 
Sbjct: 138 GGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYS 197

Query: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
            IEDLRN+I+ ATV+NA ++L IDNARLAADDFR KYE EL LR SVEADINGLR+VLD+
Sbjct: 198 IIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDD 257

Query: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
           LT+ R+DLEMQIES  EELAYL+KNHEEEM  ++G  GG+V VEM+AAPG DL+++LN+M
Sbjct: 258 LTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDM 317

Query: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
           R QYE++AE+NR++AEE F  ++  L  +++T++    S K+EI+EL+RT+Q LEIELQS
Sbjct: 318 RAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQS 377

Query: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
           QL+MK+SLE +L +T+  Y  QL++IQ  I ++EE++ Q+  E + QN EYK LLD+KTR
Sbjct: 378 QLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTR 437

Query: 408 LEQEIATYRRLLEGEDAHLSSSQF---SSGS--QSSRDV----------------TSSSR 446
           LE EI TYRRLL+GE    S ++F   +SGS    SRD+                +S +R
Sbjct: 438 LEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTR 497

Query: 447 QIRTKVMDVHDGKVVST 463
             +T V ++ DGKVVS+
Sbjct: 498 VTKTIVEELVDGKVVSS 514


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  444 bits (1143), Expect = e-125
 Identities = 256/482 (53%), Positives = 324/482 (67%), Gaps = 41/482 (8%)

Query: 3   TCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGA 62
           TC+  F S+ S+KG CG  GGI    SR+SS+ + GSCR PS  G    +SS+R    G 
Sbjct: 5   TCTPTF-STGSIKGLCGTAGGI----SRVSSIRSVGSCRVPSLAGAAGYISSAR---SGL 56

Query: 63  YGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQNL 122
            GLG    G + SS     SGF G              GG F   +G   GSEK TMQ L
Sbjct: 57  SGLGSCLPGSYLSSECHT-SGFVGS-------------GGWFC--EGSFNGSEKETMQFL 100

Query: 123 NDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATVD 182
           NDRLA+YL+KVR LE  NA+LE +I++WY+ Q P    DY  YFKTIED + KIL    +
Sbjct: 101 NDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSE 160

Query: 183 NANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESL 242
           NA ++LQIDNA+LAADDFRTKYETEL+LR  VEADINGLRR+LDELTL +ADLE Q+ESL
Sbjct: 161 NARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESL 220

Query: 243 KEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDA 302
           KEEL  LKKNHEEE++ LR Q+G  +NVE+DAAP VDL++IL +MR QYE + E NR+D 
Sbjct: 221 KEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDV 280

Query: 303 EEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEET 362
           E WF T+TEELN++V ++SE +Q  ++EI ELRRT+  LEIELQ+Q SM+ SLE++L ET
Sbjct: 281 EAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAET 340

Query: 363 KGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE 422
           + RY  QLAQ+Q +I +VE QL+++RC++E+QNQEY++LLDVK RLE EIATYR LLEGE
Sbjct: 341 EARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGE 400

Query: 423 DAHLSSSQFSSGSQSSRDVTS-----------------SSRQIRTKVMDVHDGKVVSTHE 465
           D  L     ++  +    V S                    QIRT   ++ DGKV+S+ E
Sbjct: 401 DCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSRE 460

Query: 466 QV 467
            V
Sbjct: 461 HV 462


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  436 bits (1120), Expect = e-122
 Identities = 241/442 (54%), Positives = 298/442 (67%), Gaps = 20/442 (4%)

Query: 6   RQFTSSSSMKGSCGIGG------GIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSS 59
           R   S  S  G  G GG      G GGGSSR+     GGS     +YGGG     S  S 
Sbjct: 29  RSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY--SYGGGSGGGFSASSL 86

Query: 60  GGAYGLG----GGYGGGFSSSSSSFGSGFGGGYGGGLGAGLG------GGFGGGFAGGDG 109
           GG +G G    GG  GG  SSS  FG GFGGG GGG G G G      GGFGGG  GGDG
Sbjct: 87  GGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDG 146

Query: 110 -LLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEI-KDYSPYFK 167
            +L  +EK TMQ LN RLASYLDKV+ALEEAN DLE KI+DWY ++ PA I K+YSPY+ 
Sbjct: 147 GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYN 206

Query: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
           TI+DL+++I+  TV N   LL IDN R+  DDFR K+E E NLR  V+ADINGLR+VLD 
Sbjct: 207 TIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDN 266

Query: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
           LT+ ++DLEMQ E+L+EEL  LKKNH+EEM+ L GQ  GDVNVE++ APG DL++ LN+M
Sbjct: 267 LTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDM 326

Query: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
           R +YE++  KNRKD E  + T+  ++  EV+++ + VQS   E+++LR  +Q LEIELQS
Sbjct: 327 RQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQS 386

Query: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
           QLS KA+LE SLE+TK RYC QL  IQE I ++E Q+  +R E+E QNQEY +LL +K R
Sbjct: 387 QLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMR 446

Query: 408 LEQEIATYRRLLEGEDAHLSSS 429
           LE+EI TY  LLEG      SS
Sbjct: 447 LEKEIETYHNLLEGGQEDFESS 468



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 48/107 (44%), Positives = 55/107 (51%), Gaps = 3/107 (2%)

Query: 8   FTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGG 67
           F SS + K   G  GG GG   R S   +GGS     + GG    S SR  SGG+YG G 
Sbjct: 465 FESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGS 524

Query: 68  GYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGS 114
           G GGG   S   +G G GGG+ GG G G  GG GG + GG G   GS
Sbjct: 525 GSGGG---SGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS 568



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 50/105 (47%), Positives = 53/105 (50%), Gaps = 16/105 (15%)

Query: 11  SSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYG 70
           S    G  G GGG GGGS       +GGS      YGGG   S S   SGG Y  GGG G
Sbjct: 493 SGGSYGGGGSGGGYGGGSGSRGG--SGGS------YGGG---SGSGGGSGGGY--GGGSG 539

Query: 71  GGFS-SSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGS 114
           GG S  S      G GG YGG  G+G GGG GGG+ GG G   GS
Sbjct: 540 GGHSGGSGGGHSGGSGGNYGG--GSGSGGGSGGGYGGGSGSRGGS 582



 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 45/99 (45%), Positives = 48/99 (48%), Gaps = 17/99 (17%)

Query: 19  GIGGGIGGGSSRISSVLAGGSCRAPS--TYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSS 76
           G GGG GGGS    S  +GG     S   YGGG         SG   G GGGYGGG  S 
Sbjct: 529 GSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG---------SGSGGGSGGGYGGGSGSR 579

Query: 77  SSSFGS-GFGGGYGGGLGAGLGG-----GFGGGFAGGDG 109
             S GS G G G+GG  G   GG     G GGG+ GG G
Sbjct: 580 GGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 34/84 (40%), Positives = 43/84 (51%), Gaps = 14/84 (16%)

Query: 33  SVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLG--GGYGGGFSSSSSSFGSGFGGGYGG 90
           ++L GG     S+  G + +   R  SGG+YG G  GG GG +       G G GGGYGG
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGG-RGGSGGSYGRGSRGGSGGSYG------GGGSGGGYGG 508

Query: 91  GLGA--GLGGGFGGG---FAGGDG 109
           G G+  G GG +GGG     G  G
Sbjct: 509 GSGSRGGSGGSYGGGSGSGGGSGG 532



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 33/69 (47%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 45  TYGGGLSVSSSRFSSGGA--YGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGG 102
           TY   L      F S GA   GLGG  G G S    S G G GG YGGG   G GGG+GG
Sbjct: 453 TYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRG-GSGGSYGGG---GSGGGYGG 508

Query: 103 GF--AGGDG 109
           G    GG G
Sbjct: 509 GSGSRGGSG 517



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/68 (42%), Positives = 32/68 (47%), Gaps = 18/68 (26%)

Query: 19  GIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYG-------LGGGYGG 71
           G GGG GGGS       +GGS    S +GG          SGG+YG        GGGYGG
Sbjct: 567 GSGGGYGGGSGSRGG--SGGSHGGGSGFGG---------ESGGSYGGGEEASGSGGGYGG 615

Query: 72  GFSSSSSS 79
           G   SS S
Sbjct: 616 GSGKSSHS 623


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  427 bits (1098), Expect = e-119
 Identities = 245/474 (51%), Positives = 318/474 (67%), Gaps = 35/474 (7%)

Query: 5   SRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYG 64
           S +F+S+S   GSCG     G GS R+SS  AG        +G G        ++ G  G
Sbjct: 2   SVRFSSTSRRLGSCG-----GTGSVRLSSGGAG--------FGAG--------NTCGVPG 40

Query: 65  LGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGD-GLLVGSEKVTMQNLN 123
           +G G+   F  SSS+      GGYGGGLG G        F G + GLL G+EKVTMQNLN
Sbjct: 41  IGSGFSCAFGGSSSA------GGYGGGLGGGSASC--AAFTGNEHGLLSGNEKVTMQNLN 92

Query: 124 DRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIK----DYSPYFKTIEDLRNKILTA 179
           DRLASYL+ VRALEEANADLE KI+ WY++  P   +    DYS YF  I++L+N+I++A
Sbjct: 93  DRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISA 152

Query: 180 TVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQI 239
           T  NA+V+LQ DNARL ADDFR K+E EL L  SVEADINGLRRVLDELTL R DLE+Q+
Sbjct: 153 TTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQL 212

Query: 240 ESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNR 299
           E+L EELAYLKKNHEEEM AL+   GG+VNVEM+AAPGVDL+ +LN MR +YE +AE+NR
Sbjct: 213 ETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNR 272

Query: 300 KDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSL 359
           +DAE WF  K+  L ++++ ++    S ++E+ E++RT+Q LEIELQS L+ K SLE SL
Sbjct: 273 RDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSL 332

Query: 360 EETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLL 419
            ET+  YC QLAQIQ  IG++EEQL Q+R E E Q  EY+ LLD+K  LE+EI TY  L+
Sbjct: 333 TETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLI 392

Query: 420 EGEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHD-GKVVSTHEQVLRTKN 472
           +GED   S S+   G  +    +S +  ++T V ++   GKV+S+    +  K+
Sbjct: 393 DGEDGSCSKSKGYGGPGNQTKDSSKTTIVKTVVEEIDPRGKVLSSRVHTVEEKS 446


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  421 bits (1081), Expect = e-117
 Identities = 236/424 (55%), Positives = 297/424 (70%), Gaps = 19/424 (4%)

Query: 66  GGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGG---------FAGGDG-LLVGSE 115
           G G+ G  +   S  GS F    GGGLG+  GG   GG         FAG +G LL G+E
Sbjct: 27  GAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGGLLSGNE 86

Query: 116 KVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIK----DYSPYFKTIED 171
           KVTMQNLNDRLASYLD VRALEEANA+LE KI+ WY++  P   +    DYS Y  TIED
Sbjct: 87  KVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIED 146

Query: 172 LRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLA 231
           L+NKI+++T  NANV+LQIDNARLAADDFR KYE EL L  +VEADINGLRRVLDELTL 
Sbjct: 147 LKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLC 206

Query: 232 RADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQY 291
           R D E+Q ESL EE+ YLKKNHEEEM AL+   GG+VNVEM+AAPGVDL+ +LN MR +Y
Sbjct: 207 RTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEY 266

Query: 292 EKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSM 351
           E +AE+NRKDAE WF  K+  L ++++ +S      +S+++E+RRT+Q LEI+LQS ++ 
Sbjct: 267 EALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMAT 326

Query: 352 KASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQE 411
           K SLE SL ET+  YC QLAQIQ  IG++EEQL Q+R E E Q  EY+ LLDVK  LE+E
Sbjct: 327 KHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKE 386

Query: 412 IATYRRLLEGEDAHLSSSQ-FSSGS--QSSRDVTSSSRQIRTKVMDVHD-GKVVSTHEQV 467
           I TY RL++G+    S S+ F SGS   SS+D+ S +  ++T V ++   GKV+S+    
Sbjct: 387 IETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDL-SKTTLVKTVVEELDQRGKVLSSRIHS 445

Query: 468 LRTK 471
           +  K
Sbjct: 446 IEEK 449


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  411 bits (1056), Expect = e-115
 Identities = 227/425 (53%), Positives = 303/425 (71%), Gaps = 23/425 (5%)

Query: 4   CSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAY 63
           C +   SS S+K      GG  GGS+R+S++ +  SC+ PS     LS  +  FS+    
Sbjct: 5   CLKAGFSSGSLKSP----GGASGGSTRVSAMYSSSSCKLPS-----LSPVARSFSACSV- 54

Query: 64  GLGGGYGGGFSSSSSSF--GSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQN 121
           GLG       S   +      GF   Y GG         GG F  G+G+L G+EK TMQ+
Sbjct: 55  GLGRSSYRATSCLPALCLPAGGFATSYSGG---------GGWF--GEGILTGNEKETMQS 103

Query: 122 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATV 181
           LNDRLA YL+KVR LE+ NA LE +IR+W ++Q P    DY  YF+TIE+L+ K L +  
Sbjct: 104 LNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKA 163

Query: 182 DNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIES 241
           +NA ++++IDNA+LAADDFRTKYETE++LR  VE+DINGLRR+LD+LTL ++DLE Q+ES
Sbjct: 164 ENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVES 223

Query: 242 LKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKD 301
           LKEEL  LKKNHEEE+N+LR Q+G  +NVE+DAAP VDL+R+L EMR QYE + E NR+D
Sbjct: 224 LKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRD 283

Query: 302 AEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEE 361
           AE+W  T++EELN++V ++SE +QS ++EI ELRRT+  LEIELQ+Q SM+ +LE++L E
Sbjct: 284 AEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAE 343

Query: 362 TKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEG 421
           T+ RY  QLAQ+Q MI +VE QLA++R ++E+QNQEY++LLDV+ RLE EI TYR LLE 
Sbjct: 344 TEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLES 403

Query: 422 EDAHL 426
           ED+ L
Sbjct: 404 EDSKL 408


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  403 bits (1036), Expect = e-112
 Identities = 232/459 (50%), Positives = 298/459 (64%), Gaps = 27/459 (5%)

Query: 28  SSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGG 87
           S R+SS  +  SC  P+T  G L +          YG G  +G G S   S  GSGF   
Sbjct: 2   SLRLSSA-SRRSCPRPTT--GSLRL----------YGGGTSFGTGNSCGISGIGSGFSSA 48

Query: 88  YGGGLGAGLGGGFG--GGFAGGD-GLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLE 144
           +GG    G  GG     GF   + GLL G+EKVTMQNLNDRLASYLD V ALEEANADLE
Sbjct: 49  FGGSSSGGNTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLE 108

Query: 145 VKIRDWYQRQRPAEIK----DYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDF 200
            KI+ WY++  P   +    DYS YF  I+DL+N+I+ +T  NAN +LQIDNARL ADDF
Sbjct: 109 QKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDF 168

Query: 201 RTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNAL 260
           R KYE EL L  SVEAD+NGLRRVLDE+TL R DLE+Q E+L EE+ YLKKNH+EEM  L
Sbjct: 169 RLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVL 228

Query: 261 RGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATN 320
           +   GG+VNVEM+AAPGVDL+ +LN MR +YE +AE+NR+DAE WF  K+  L ++++ +
Sbjct: 229 QCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISED 288

Query: 321 SELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSV 380
                S ++E++E++RT+Q LEIELQS L+ K SLE SL ET+  YC QLAQIQ  IG++
Sbjct: 289 VGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGAL 348

Query: 381 EEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRD 440
           EEQL Q+R E E Q  EY+ LLD+K  LE+EI TY  L+ G+D    S  + S    S +
Sbjct: 349 EEQLHQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGN 408

Query: 441 VTSSSRQ-----IRTKVMDVHD--GKVVSTHEQVLRTKN 472
           V S  +      +  KV++  D   K+++T    L  K+
Sbjct: 409 VGSQVKDPAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  394 bits (1011), Expect = e-109
 Identities = 204/383 (53%), Positives = 280/383 (73%), Gaps = 10/383 (2%)

Query: 88  YGGGLGAGLG-------GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEAN 140
           YGG  G G+          +G    GG  L VG+EK+ MQNLNDRLASYL+KVR LE++N
Sbjct: 36  YGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSN 95

Query: 141 ADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDF 200
           + LEV+I+ WY+   P   +DYS Y++ IE+LR++I  A + NA  +LQIDNA+LAA+DF
Sbjct: 96  SKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDF 155

Query: 201 RTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNAL 260
           R KYETE  +R++VEAD+ GL +V D+LTL + DLE+QIE L ++LA LKK H+EE++ L
Sbjct: 156 RLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGL 215

Query: 261 RGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATN 320
              +G  VNVE+DAAPG++L  I+NEMR +YE MA+KN ++A+E F  +T  L ++V  N
Sbjct: 216 HKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVN 275

Query: 321 SELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSV 380
           +E ++  + +++ELRRT Q+LEIELQS LSMK SLE++LEETK RY  QLA +Q ++ S+
Sbjct: 276 TEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSL 335

Query: 381 EEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRD 440
           E QL Q+R  ME+QN EY ILLD+KTRLEQEIATYRRLLEGED  + ++++   +   RD
Sbjct: 336 EAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGED--VKTTEYQLSTLEERD 393

Query: 441 VTSSSRQIRTKVMDVHDGKVVST 463
           +   +R+I+T V +V DGKVVS+
Sbjct: 394 I-KKTRKIKTVVQEVVDGKVVSS 415


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  382 bits (981), Expect = e-106
 Identities = 195/334 (58%), Positives = 260/334 (77%)

Query: 108 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFK 167
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108

Query: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
           TIE+L+ KIL    +NA +++QIDNA+LAADDFRTKY+TEL+LR  VE+DINGLRR+LDE
Sbjct: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168

Query: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
           LTL ++DLE Q+ESLKEEL  LK NHE+E+N LR Q+G  +NVE+DAAP VDL+R+LNE 
Sbjct: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228

Query: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
           R QYE + E NR++ E+WF T+TEELN++V ++SE +QS ++EI ELRRT+  LEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
           Q +++ SLEN+L E++ RY  QL+Q+Q +I +VE QLA++R ++E+QNQEY++LLDV+ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 408 LEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRDV 441
           LE EI TYR LLE ED +L S+  ++ +  S+ +
Sbjct: 349 LECEINTYRSLLESEDCNLPSNPCATTNACSKPI 382


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  380 bits (977), Expect = e-105
 Identities = 194/322 (60%), Positives = 255/322 (79%)

Query: 108 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFK 167
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFK 108

Query: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
           TIE+L+ KIL +  +NA +++QIDNA+LA+DDFRTKYETEL+LR  VE+DINGLRR+LDE
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168

Query: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
           LTL R+DLE Q+ESLKEEL  LK+NHE+E+N LR Q+G  +NVE+DAAP VDL+++LNE 
Sbjct: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228

Query: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
           R QYE + E NR++ E+WF T+TEELN++V ++SE +QS ++EI ELRRT+  LEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
           Q +++ SLEN+L E++ RY  QL+Q+Q +I +VE QLA++R ++E+QNQEY++LLDV+ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 408 LEQEIATYRRLLEGEDAHLSSS 429
           LE EI TYR LLE ED  L S+
Sbjct: 349 LECEINTYRSLLESEDCKLPSN 370


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  378 bits (971), Expect = e-105
 Identities = 217/408 (53%), Positives = 272/408 (66%), Gaps = 16/408 (3%)

Query: 35  LAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGL-- 92
           L+GGS R  S  G G      R S GG   + G    G S + SSF     G   GG   
Sbjct: 5   LSGGSRRICSRTGSG------RLSGGGTGFVAGNVCVG-SGARSSFSCTLEGISSGGSFC 57

Query: 93  --GAGLGGGFGGGFAGGD-GLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRD 149
             G GLG G   GF G +  LL G+EKVTMQNLNDRLASYLD V ALEEANADLE KI+ 
Sbjct: 58  NSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKG 117

Query: 150 WYQRQRPAEIK----DYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYE 205
            Y++  P   +    DYS YF  IEDL+ +I +AT+ NA+++LQ DNARL ADDFR KYE
Sbjct: 118 RYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYE 177

Query: 206 TELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVG 265
            EL L  SVEAD +GLRRVLDELTL   DLE+Q E+L EEL YLKK+HEEEM  L+   G
Sbjct: 178 NELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAG 237

Query: 266 GDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQ 325
           G+VNVEM+A PGVDL+ +LN MR +YE +AE+NRKDAE WF  ++  L ++++ +     
Sbjct: 238 GNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAAT 297

Query: 326 SGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLA 385
           + ++E++EL+R +Q LEIELQS +++K S E SL ET+G YC QL QIQ+ IG +EEQL 
Sbjct: 298 AARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQ 357

Query: 386 QLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSS 433
           Q+R E E Q  EY+ LLDVK  LE+EI  Y  LL+GE+    S+ + S
Sbjct: 358 QIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKS 405


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  377 bits (967), Expect = e-104
 Identities = 193/336 (57%), Positives = 260/336 (77%)

Query: 108 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFK 167
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108

Query: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
           TIE+L+ KIL +  +NA +++QIDNA+LAADDFRTKY+TE +LR  VE+DIN LRR+LDE
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDE 168

Query: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
           LTL R+DLE Q+ESLKEEL  LK+NHE+E+N LR Q+G  +NVE+DAAP VDL+++LNE 
Sbjct: 169 LTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNET 228

Query: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
           R+QYE + E NR++ E+WF T+TEELN++V ++SE +QS ++EI ELRRT+  LEIELQ+
Sbjct: 229 RNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
           Q +++ SLEN+L E++ RY  QL+Q+Q +I +VE QLA++R ++E+QNQEY++LLDV+ R
Sbjct: 289 QHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 408 LEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRDVTS 443
           LE EI TYR LLE ED  L S+  ++ +   + + S
Sbjct: 349 LECEINTYRSLLESEDCKLPSNPCATTNACEKPIGS 384


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  373 bits (958), Expect = e-103
 Identities = 195/342 (57%), Positives = 256/342 (74%)

Query: 94  AGLGGGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQR 153
           +G+ G  G G    +G   G+EK TMQ LNDRLASYL +VR LE+ NA+LE +I++    
Sbjct: 75  SGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHS 134

Query: 154 QRPAEIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMS 213
           Q      DY  +F+TIE+L+ KIL    +NA +++ IDNA+LAADDFR KYE EL +R  
Sbjct: 135 QVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQL 194

Query: 214 VEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMD 273
           VEADINGLRR+LD+LTL +ADLE Q+ESLKEEL  LKKNHEEE+ +LR Q+G  +N+E+D
Sbjct: 195 VEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVD 254

Query: 274 AAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISE 333
           AAP VDL+R+L EMR QYE M E NR+D EEWF  + EELN++VAT+SE +Q+ +S+I +
Sbjct: 255 AAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIID 314

Query: 334 LRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQ 393
           LRRT+  LEIELQ+Q S++ SLEN+L E++ RY  QLAQ+Q MI +VE QLA++R ++E+
Sbjct: 315 LRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLER 374

Query: 394 QNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSGS 435
           QNQEY++LLDV+ RLE EI TYR LLE ED  L  +  S+ S
Sbjct: 375 QNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPS 416


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  371 bits (953), Expect = e-103
 Identities = 186/319 (58%), Positives = 250/319 (78%)

Query: 108 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFK 167
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  I++  Q+Q P     Y  YFK
Sbjct: 91  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFK 150

Query: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
           TIE+L+ KIL A  +NA +++ IDNA+LA+DDFR+KY+TE +LR+ VE+DIN +RR+LDE
Sbjct: 151 TIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDE 210

Query: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
           LTL ++DLE Q+ESL+EEL  LKKNHEEE+N LR Q+G  +NVE+D AP VDL+++LNE 
Sbjct: 211 LTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNET 270

Query: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
           R QYE + E NR++ E+WF T+TEELN++V ++SE +QS ++EI ELRRT+  LEIELQ+
Sbjct: 271 RSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQA 330

Query: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
           Q +++ SLEN+L E++  Y  QL+Q+Q +I +VE QLA++RC++E+QNQEY++LLDV+ R
Sbjct: 331 QHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRAR 390

Query: 408 LEQEIATYRRLLEGEDAHL 426
           LE EI TYR LLE ED  L
Sbjct: 391 LECEINTYRSLLESEDCKL 409


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  351 bits (900), Expect = 9e-97
 Identities = 204/427 (47%), Positives = 287/427 (67%), Gaps = 18/427 (4%)

Query: 38  GSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLG 97
           GS +APS   G   VSS+     GA       GG  S  S S  + F GG G G   GL 
Sbjct: 17  GSVQAPSY--GARPVSSAASVYAGA-------GGSGSRISVSRSTSFRGGMGSG---GLA 64

Query: 98  GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPA 157
            G  GG AG  G  + +EK TMQ+LNDRLASYLD+VR+LE  N  LE KIR+  +++ P 
Sbjct: 65  TGIAGGLAGMGG--IQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP- 121

Query: 158 EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEAD 217
           +++D+S YFK IEDLR +I   TVDNA ++LQIDNARLAADDFR KYETEL +R SVE D
Sbjct: 122 QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEND 181

Query: 218 INGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGD-VNVEMDAAP 276
           I+GLR+V+D+  + R  LE +IE+LKEEL ++KKNHEEE+  L+ Q+    + VE+DA  
Sbjct: 182 IHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPK 241

Query: 277 GVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRR 336
             DL++I+ ++R QY+++A KNR++ ++++  + EE    V T S  V + ++ ++ELRR
Sbjct: 242 SQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRR 301

Query: 337 TMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQ 396
           T+Q+LEI+L S  ++KASLENSL E + RY +Q+ Q+  ++  +E +LAQ R E ++Q Q
Sbjct: 302 TVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQ 361

Query: 397 EYKILLDVKTRLEQEIATYRRLLE-GEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVM-D 454
           EY+ LL++K +LE EIATYRRLLE GED +L  +  SS S  +   T++ R +  KV+ +
Sbjct: 362 EYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSE 421

Query: 455 VHDGKVV 461
            +D KV+
Sbjct: 422 TNDTKVL 428


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  351 bits (900), Expect = 9e-97
 Identities = 204/427 (47%), Positives = 287/427 (67%), Gaps = 18/427 (4%)

Query: 38  GSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLG 97
           GS +APS   G   VSS+     GA       GG  S  S S  + F GG G G   GL 
Sbjct: 17  GSVQAPSY--GARPVSSAASVYAGA-------GGSGSRISVSRSTSFRGGMGSG---GLA 64

Query: 98  GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPA 157
            G  GG AG  G  + +EK TMQ+LNDRLASYLD+VR+LE  N  LE KIR+  +++ P 
Sbjct: 65  TGIAGGLAGMGG--IQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP- 121

Query: 158 EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEAD 217
           +++D+S YFK IEDLR +I   TVDNA ++LQIDNARLAADDFR KYETEL +R SVE D
Sbjct: 122 QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEND 181

Query: 218 INGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGD-VNVEMDAAP 276
           I+GLR+V+D+  + R  LE +IE+LKEEL ++KKNHEEE+  L+ Q+    + VE+DA  
Sbjct: 182 IHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPK 241

Query: 277 GVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRR 336
             DL++I+ ++R QY+++A KNR++ ++++  + EE    V T S  V + ++ ++ELRR
Sbjct: 242 SQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRR 301

Query: 337 TMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQ 396
           T+Q+LEI+L S  ++KASLENSL E + RY +Q+ Q+  ++  +E +LAQ R E ++Q Q
Sbjct: 302 TVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQ 361

Query: 397 EYKILLDVKTRLEQEIATYRRLLE-GEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVM-D 454
           EY+ LL++K +LE EIATYRRLLE GED +L  +  SS S  +   T++ R +  KV+ +
Sbjct: 362 EYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSE 421

Query: 455 VHDGKVV 461
            +D KV+
Sbjct: 422 TNDTKVL 428


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  343 bits (879), Expect = 3e-94
 Identities = 176/331 (53%), Positives = 245/331 (74%)

Query: 108 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFK 167
           DG+   +EK TMQ LNDRLASYL+KVR+LEE NA+LE +I++  ++  P    DY  YF 
Sbjct: 82  DGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFN 141

Query: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
           TIEDL+ KIL    +N+ + +Q+DN +LA DDF++KYE+EL+LR  +EADI+ L  +L+E
Sbjct: 142 TIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEE 201

Query: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
           LTL ++DLE  +ESLKE+L  LKKNHEEE+N LR Q+G  ++VE+D AP +DL+R+L+EM
Sbjct: 202 LTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEM 261

Query: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
           R Q E +   NR++AEEW   +TEELN++  +++E +Q  + EI EL+RT   LEIELQ+
Sbjct: 262 RCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQA 321

Query: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
           Q S+  SLE ++ ET+ +Y  QLAQIQ +I ++E QLA++RC++E+QNQEY++LLDVK R
Sbjct: 322 QQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKAR 381

Query: 408 LEQEIATYRRLLEGEDAHLSSSQFSSGSQSS 438
           LE EI TY  LL+ ED+ LS S  S+   SS
Sbjct: 382 LEGEINTYWGLLDSEDSRLSCSPCSTTCTSS 412


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  326 bits (835), Expect = 3e-89
 Identities = 182/393 (46%), Positives = 255/393 (64%), Gaps = 33/393 (8%)

Query: 107 GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYF 166
           G+G+   +EK TMQ LN+RLA+YL KVR LE  NA+LE KI++   ++ P    DY  Y+
Sbjct: 89  GEGIN-SNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYY 147

Query: 167 KTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLD 226
            TIE+L+ KIL    +N+ ++ QIDN +L ADD R KYE E++LR  VE+D NGL+++L+
Sbjct: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207

Query: 227 ELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNE 286
            LTL +ADLE Q++SLKEEL  LK NH+EE+N+L+ Q+G  +++E+ AAP  DL+++L E
Sbjct: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267

Query: 287 MRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQ 346
           MR QYE + E NRKD E+WF T+ EELN++V T+S+  Q  + EI ELRR++  LE+ELQ
Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327

Query: 347 SQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKT 406
           +Q  M+ S E  L ET+ RY   L QIQ +I ++E QLA++RC +E+QNQEY+ILLDVK+
Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387

Query: 407 RLEQEIATYRRLLEGEDAHLS-------------SSQFSSGSQSSRDVTSSSR------- 446
           RLE EI TYR LLE  D                 +S  S   +S+    +SS        
Sbjct: 388 RLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEH 447

Query: 447 ------------QIRTKVMDVHDGKVVSTHEQV 467
                       +I T   ++ DGKV+S++E V
Sbjct: 448 CSACGPLSRILVKICTITKEIKDGKVISSYEHV 480


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  322 bits (826), Expect = 4e-88
 Identities = 172/336 (51%), Positives = 236/336 (70%)

Query: 98  GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPA 157
           G  G   A G+  L G EK TMQ LNDRLA+YL+KVR LE+ NA+LE  + +  +     
Sbjct: 87  GNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHEST 146

Query: 158 EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEAD 217
              DY  YF TIE+L+ KIL +  +NA +++QIDNA+LAADDFR K E+E +LR  VEAD
Sbjct: 147 VCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEAD 206

Query: 218 INGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPG 277
             G +++LD+ TLA+ADLE Q ESLKEE   LK NHE+E+  LR Q+G  + +E+D  P 
Sbjct: 207 KCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPT 266

Query: 278 VDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRT 337
           +DL+R+L EMR QYE M E NR+D E+WF  ++E ++ +  + SE +Q  +SEI ELR T
Sbjct: 267 IDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCT 326

Query: 338 MQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQE 397
           +  LE+E Q+Q ++K  L+NSL E + R+  +LAQ+Q +I +VEEQL+++R ++E+QNQE
Sbjct: 327 VNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQE 386

Query: 398 YKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSS 433
           Y++LLDVKTRLE EIATYR LLE ED  L  +  S+
Sbjct: 387 YQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCST 422


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  316 bits (810), Expect = 3e-86
 Identities = 168/336 (50%), Positives = 232/336 (69%)

Query: 98  GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPA 157
           G  G   A G   L G EK TM+ LNDRLA+YL+KVR LE+ NA+LE  + +  +     
Sbjct: 87  GNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHEST 146

Query: 158 EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEAD 217
              DY  YF+TIE+L+ KIL +  +NA +++QIDNA+LAADDFR K E+E +L   VEAD
Sbjct: 147 VCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEAD 206

Query: 218 INGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPG 277
             G +++LD+ TLA+ADLE Q ESLKEE   LK NHE+E+  LR Q+G    +E+D  P 
Sbjct: 207 KCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPT 266

Query: 278 VDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRT 337
           +DL+R+L EMR QYE M E N +D E+WF  ++E ++ +  + SE +Q  +SEI ELR T
Sbjct: 267 IDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCT 326

Query: 338 MQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQE 397
           +  LE+E Q+Q ++K  L+NSL E + RY  +LAQ+Q +I ++EEQL+++R ++E+QNQE
Sbjct: 327 VNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQE 386

Query: 398 YKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSS 433
           Y++LLDVK RLE EIATYR LLE ED  L  +  S+
Sbjct: 387 YQVLLDVKARLENEIATYRNLLESEDCKLPCNPCST 422


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  311 bits (796), Expect = 1e-84
 Identities = 178/415 (42%), Positives = 258/415 (62%), Gaps = 15/415 (3%)

Query: 53  SSSRFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGL------GGGFGGGFAG 106
           S S+  S   +G GGG+G   S   +    G  GG    L          GG +G G + 
Sbjct: 6   SFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSS 65

Query: 107 GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYF 166
              LL G+ K TMQNLNDRLASYL+KVRALEEAN  LE +I  W+Q++ P   KDYS Y 
Sbjct: 66  P--LLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYE 123

Query: 167 KTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLD 226
           + I  L+ +I+   + NA ++L IDNAR+A DDF  KYE E + +  +E ++ GLRR LD
Sbjct: 124 ENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLD 183

Query: 227 ELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNE 286
            LT+   DLE ++E +++EL  +KK+HE+EM         +VNV++D  P  DL ++L +
Sbjct: 184 NLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLED 243

Query: 287 MRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQ 346
           MR +YE + +K  +D + W+  ++  +++E A+ +  VQS + +I EL+RT Q LEI+LQ
Sbjct: 244 MRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQALEIDLQ 302

Query: 347 SQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKT 406
           +Q S K++LEN L ET+ RY  +L  +QE+I   EE+L QLR E+E+QN EY++LL +KT
Sbjct: 303 TQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKT 362

Query: 407 RLEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVV 461
            LE+EI TYRRLLEGE     S      S+SS  V S++ +I+    +  +G++V
Sbjct: 363 HLEKEITTYRRLLEGE-----SEGTREESKSSMKV-SATPKIKAITQETINGRLV 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,629,292
Number of Sequences: 37866
Number of extensions: 768651
Number of successful extensions: 20283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 464
Number of HSP's successfully gapped in prelim test: 663
Number of HSP's that attempted gapping in prelim test: 6399
Number of HSP's gapped (non-prelim): 6048
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.