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Search of human proteins with 153945736
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153945736 keratin 27 [Homo sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153945736 keratin 27 [Homo sapiens] 907 0.0
gi|31559829 keratin 25 [Homo sapiens] 717 0.0
gi|114431246 keratin 25D [Homo sapiens] 697 0.0
gi|31559815 keratin 26 [Homo sapiens] 635 0.0
gi|192807292 keratin 24 [Homo sapiens] 469 e-132
gi|195972866 keratin 10 [Homo sapiens] 460 e-129
gi|4557699 keratin 12 [Homo sapiens] 447 e-125
gi|15431310 keratin 14 [Homo sapiens] 427 e-119
gi|4557701 keratin 17 [Homo sapiens] 421 e-118
gi|24430192 keratin 16 [Homo sapiens] 421 e-118
gi|131412225 keratin 13 isoform a [Homo sapiens] 418 e-117
gi|24430190 keratin 15 [Homo sapiens] 415 e-116
gi|131412228 keratin 13 isoform b [Homo sapiens] 415 e-116
gi|24234699 keratin 19 [Homo sapiens] 387 e-107
gi|55956899 keratin 9 [Homo sapiens] 342 4e-94
gi|4504927 keratin 36 [Homo sapiens] 340 2e-93
gi|27894337 keratin 20 [Homo sapiens] 329 4e-90
gi|94538345 keratin 35 [Homo sapiens] 322 4e-88
gi|116488398 keratin 32 [Homo sapiens] 310 1e-84
gi|14917117 keratin 33A [Homo sapiens] 306 3e-83
gi|14917115 keratin 31 [Homo sapiens] 300 2e-81
gi|10337581 type I hair keratin 3B [Homo sapiens] 298 9e-81
gi|14917119 keratin 34 [Homo sapiens] 288 5e-78
gi|125490370 type I hair keratin KA36 [Homo sapiens] 286 3e-77
gi|27894339 keratin 23 [Homo sapiens] 284 1e-76
gi|40354195 keratin 18 [Homo sapiens] 281 1e-75
gi|4557888 keratin 18 [Homo sapiens] 281 1e-75
gi|148277620 type I hair keratin KA35 [Homo sapiens] 276 3e-74
gi|55770882 keratin 37 [Homo sapiens] 256 2e-68
gi|15431318 keratin 38 [Homo sapiens] 254 1e-67
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 907 bits (2344), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGG 60
MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGG
Sbjct: 1 MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGG 60
Query: 61 GLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY 120
GLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY
Sbjct: 61 GLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY 120
Query: 121 EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE 180
EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE
Sbjct: 121 EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE 180
Query: 181 LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN 240
LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN
Sbjct: 181 LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN 240
Query: 241 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA 300
VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA
Sbjct: 241 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA 300
Query: 301 RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 360
RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV
Sbjct: 301 RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 360
Query: 361 RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGNQTKDSSKTTI 420
RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGNQTKDSSKTTI
Sbjct: 361 RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGNQTKDSSKTTI 420
Query: 421 VKTVVEEIDPRGKVLSSRVHTVEEKSTKVNNKNEQRVSS 459
VKTVVEEIDPRGKVLSSRVHTVEEKSTKVNNKNEQRVSS
Sbjct: 421 VKTVVEEIDPRGKVLSSRVHTVEEKSTKVNNKNEQRVSS 459
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 717 bits (1852), Expect = 0.0
Identities = 366/452 (80%), Positives = 397/452 (87%), Gaps = 11/452 (2%)
Query: 1 MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGG 60
MS+R SS SRR TGS+RL GG FG GN+CG+ GIGSGFS AFGGSSS G GG
Sbjct: 1 MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG 60
Query: 61 GLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY 120
G CA FT NE GLLSGNEKVTMQNLNDRLASYL++V ALEEANADLEQKIKGWY
Sbjct: 61 G-----NPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWY 115
Query: 121 EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE 180
EKFGPGSCRGLDHDYSRYFPIID+LKNQII++TTSNA+ VLQ DNARLTADDFRLK+ENE
Sbjct: 116 EKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENE 175
Query: 181 LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN 240
LALHQSVEAD+NGLRRVLDE+TLCRTDLEIQ ETLSEE+ YLKKNH+EEM+ LQCAAGGN
Sbjct: 176 LALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGN 235
Query: 241 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA 300
VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQIS+D GATTSA
Sbjct: 236 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSA 295
Query: 301 RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 360
RNEL EMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV
Sbjct: 296 RNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 355
Query: 361 RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSC------SKSKGYGGPGNQTKD 414
RTETEGQKLEYEQLLDIK+HLEKEIETYCLLI G+DG+C SK G G G+Q KD
Sbjct: 356 RTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKD 415
Query: 415 SSKTTIVKTVVEEIDPRGKVLSSRVHTVEEKS 446
+K +VK V+EE+D R K+L++R+H++EEKS
Sbjct: 416 PAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 697 bits (1798), Expect = 0.0
Identities = 356/462 (77%), Positives = 400/462 (86%), Gaps = 5/462 (1%)
Query: 1 MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGS--SSAGGY 58
MS++FS+ SR + G GSVR +GGAGF + CG GS FSCA GG S GG
Sbjct: 1 MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60
Query: 59 GGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKG 118
G G+A+C F G+E GLLSGNEKVTMQNLNDRLASYL+NVRALEEANA+LE+KIKG
Sbjct: 61 HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120
Query: 119 WYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFE 178
WYEK+GPGSCRGLDHDYSRY I++LKN+IIS+TT+NA+V+LQ DNARL ADDFRLK+E
Sbjct: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180
Query: 179 NELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAG 238
NEL LHQ+VEADINGLRRVLDELTLCRTD E+Q E+LSEE+ YLKKNHEEEMKALQCAAG
Sbjct: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240
Query: 239 GNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATT 298
GNVNVEMNAAPGVDL VLLNNMRAEYEALAEQNR+DAEAWFNEKSASLQQQIS D+GA T
Sbjct: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300
Query: 299 SARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLH 358
AR++L EM+RTLQTLEI+LQSL+ATKHSLECSLTETESNYC QLAQIQAQIGALEEQLH
Sbjct: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360
Query: 359 QVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGY--GGPGNQTKDSS 416
QVRTETEGQKLEYE LLD+KVHLEKEIETYC LIDG+ SCSKSKG+ G PGN +KD S
Sbjct: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLS 420
Query: 417 KTTIVKTVVEEIDPRGKVLSSRVHTVEEKSTKV-NNKNEQRV 457
KTT+VKTVVEE+D RGKVLSSR+H++EEK++K+ N K EQRV
Sbjct: 421 KTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRV 462
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 635 bits (1638), Expect = 0.0
Identities = 339/469 (72%), Positives = 374/469 (79%), Gaps = 14/469 (2%)
Query: 1 MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGY-- 58
MS R S SRR+ C TGS RLS GG GF AGN C G S FSC G SS G +
Sbjct: 1 MSFRLSGGSRRI--CSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCN 58
Query: 59 -GGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIK 117
GGGLG G+ CA F GNEH LLSGNEKVTMQNLNDRLASYL++V ALEEANADLEQKIK
Sbjct: 59 SGGGLGSGA--CAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIK 116
Query: 118 GWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKF 177
G YEK PGS R DHDYSRYF +I++LK QI SAT NA +VLQNDNARLTADDFRLK+
Sbjct: 117 GRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKY 176
Query: 178 ENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAA 237
ENELALH SVEAD +GLRRVLDELTLC TDLEIQ ETLSEEL YLKK+HEEEM+ LQ A
Sbjct: 177 ENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTA 236
Query: 238 GGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGAT 297
GGNVNVEMNA PGVDLTVLLNNMRAEYE LAEQNR+DAEAWFNE+SA+LQQQISD GA
Sbjct: 237 GGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAA 296
Query: 298 TSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQL 357
T+ARNEL E+KR LQTLEIELQSL+A KHS ECSL ETE NYC QL QIQ QIG +EEQL
Sbjct: 297 TAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQL 356
Query: 358 HQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED----GSCSKSKGYG--GPGNQ 411
Q+RTETEGQKLEYEQLLD+K+ LEKEI+ YC L+DGE+ +C KSKGY GNQ
Sbjct: 357 QQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQ 416
Query: 412 TKDSSKTTIVKTVVEEIDPRGKVLSSRVHTVEEKSTKVNNKN-EQRVSS 459
KDS++ TIVKTVVEE+D G +LS RVH+VEEKS+K++N EQRV S
Sbjct: 417 AKDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPS 465
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 469 bits (1208), Expect = e-132
Identities = 268/467 (57%), Positives = 329/467 (70%), Gaps = 41/467 (8%)
Query: 13 GSCG-GTGSVRLSSGGAGFGAGNTCGVP---GIGSGFSCAFGGSSSAGG----YGGGLGG 64
GSC G G S G GFG G++ G G GSGF + SS A G YGGG+GG
Sbjct: 69 GSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGG 128
Query: 65 GSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFG 124
G + GL SG EK TMQNLNDRLA+YL+ VRALEEAN DLE KIK WY+K+G
Sbjct: 129 GVG--------DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG 180
Query: 125 PGSCRG-LDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183
PGS G DYS+Y+ II++L+NQII+AT NA ++L DNARL ADDFRLK+ENEL L
Sbjct: 181 PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL 240
Query: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNV 243
QSVEADINGLR+VLD+LT+ R+DLE+Q+E+ +EELAYL+KNHEEEMK +Q ++GG V V
Sbjct: 241 RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV 300
Query: 244 EMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNE 303
EMNAAPG DLT LLN+MRA+YE LAEQNRR+AE FN++SASLQ QIS DAGA TSA+NE
Sbjct: 301 EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE 360
Query: 304 LIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTE 363
+ E+KRTLQ LEIELQS LA K SLE +L +TE+ Y AQL++IQ QI ALEE++ Q+ E
Sbjct: 361 ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE 420
Query: 364 TEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGN------------- 410
T+ Q EY+QLLDIK LE EIETY L+DGE G S ++ +GG +
Sbjct: 421 TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAE-FGGRNSGSVNMGSRDLVSG 479
Query: 411 ---------QTKDSSKTTIVKTVVEEIDPRGKVLSSRVHTVEEKSTK 448
Q +DSSKT + KT+VEE+ GKV+SS+V ++ E K
Sbjct: 480 DSRSGSCSGQGRDSSKTRVTKTIVEEL-VDGKVVSSQVSSISEVKVK 525
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 460 bits (1183), Expect = e-129
Identities = 256/422 (60%), Positives = 304/422 (72%), Gaps = 20/422 (4%)
Query: 5 FSSTSRRLGSCGGTGSVRLSSGG----AGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGG 60
FS S GS GG G SSGG GFG G+ G G S F ++GGS G +GG
Sbjct: 52 FSGGSFSRGSSGG-GCFGGSSGGYGGLGGFGGGSFRGSYG-SSSFGGSYGGSFGGGSFGG 109
Query: 61 G-LGGGSASCAAFTGN------------EHGLLSGNEKVTMQNLNDRLASYLENVRALEE 107
G GGGS F G + GLLSGNEKVTMQNLNDRLASYL+ VRALEE
Sbjct: 110 GSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEE 169
Query: 108 ANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNAR 167
+N +LE KIK WYEK G S +G DYS+Y+ ID+LKNQI++ TT NA+++LQ DNAR
Sbjct: 170 SNYELEGKIKEWYEKHG-NSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNAR 228
Query: 168 LTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHE 227
L ADDFRLK+ENE+AL QSVEADINGLRRVLDELTL + DLE+Q+E+L+EELAYLKKNHE
Sbjct: 229 LAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHE 288
Query: 228 EEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQ 287
EEMK L+ + G+VNVEMNAAPGVDLT LLNNMR++YE LAEQNR+DAEAWFNEKS L
Sbjct: 289 EEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELT 348
Query: 288 QQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQ 347
+I ++ +S ++E+ E++R +Q LEIELQS LA K SLE SL ETE YC QL+QIQ
Sbjct: 349 TEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQ 408
Query: 348 AQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGG 407
AQI ALEEQL Q+R ETE Q EY+QLLDIK+ LE EI+TY L++GE S +G G
Sbjct: 409 AQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGS 468
Query: 408 PG 409
G
Sbjct: 469 FG 470
Score = 47.8 bits (112), Expect = 2e-05
Identities = 30/66 (45%), Positives = 38/66 (57%), Gaps = 4/66 (6%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
G GG S SSGG G+G G++ G G G S +GG SS GG GGG GGGS+ +
Sbjct: 497 GGYGGGSSGGGSSGG-GYGGGSSSG--GHGGSSSGGYGGGSSGGG-GGGYGGGSSGGGSS 552
Query: 73 TGNEHG 78
+G +G
Sbjct: 553 SGGGYG 558
Score = 42.4 bits (98), Expect = 9e-04
Identities = 28/62 (45%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
GS GG G S GG G+G G++ G G G GGSS GGYGGG GG +S +
Sbjct: 457 GSSGGGGRGGGSFGG-GYGGGSSGGGSS-GGGHGGGHGGSSG-GGYGGGSSGGGSSGGGY 513
Query: 73 TG 74
G
Sbjct: 514 GG 515
Score = 42.4 bits (98), Expect = 9e-04
Identities = 29/69 (42%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGL---GGGSASC 69
G GG+ S GG G G G + G G G G S GG SS GGYGGG G G +S
Sbjct: 472 GYGGGSSGGGSSGGGHGGGHGGSSG-GGYGGGSS---GGGSSGGGYGGGSSSGGHGGSSS 527
Query: 70 AAFTGNEHG 78
+ G G
Sbjct: 528 GGYGGGSSG 536
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/59 (45%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 13 GSCGGTGSVRLSSGG------AGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGG 65
GS GG SSGG G+G G++ G G G G + GGSSS GGYGGG G
Sbjct: 507 GSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGG-GYGGGSSGGGSSSGGGYGGGSSSG 564
Score = 40.4 bits (93), Expect = 0.003
Identities = 27/59 (45%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCA--FGGSSSAGG-YGGGLGGGSAS 68
G G GS GG G G++ G G G G S +GG SS GG GGG GGGS+S
Sbjct: 461 GGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSS 519
Score = 33.9 bits (76), Expect = 0.32
Identities = 20/43 (46%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 40 GIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAFTGNEHGLLSG 82
G GS GG S GGYGGG GG +S G HG SG
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGH-GGGHGGSSG 496
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 447 bits (1149), Expect = e-125
Identities = 244/445 (54%), Positives = 322/445 (72%), Gaps = 18/445 (4%)
Query: 14 SCGG---TGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAG---GYGGGLGGGSA 67
SCGG S+ SS G G G+G++ G+G+G+ A GG S G G+GG GGGS
Sbjct: 52 SCGGGFSAASMFGSSSGFGGGSGSSMA-GGLGAGYGRALGGGSFGGLGMGFGGSPGGGSL 110
Query: 68 SCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGS 127
+GN+ GLLSG+EK TMQNLNDRLASYL+ VRALEEAN +LE KI+ WYE G G+
Sbjct: 111 GI--LSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGT 168
Query: 128 CRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSV 187
DYS+Y+P+I++L+N+IISA+ NA ++LQ DNARL A+DFR+K+ENELAL Q V
Sbjct: 169 ADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGV 228
Query: 188 EADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNA 247
EADINGLRRVLDELTL RTDLE+Q+E+L+EELAY+KKNHE+E+++ + G V+VEM+A
Sbjct: 229 EADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDA 288
Query: 248 APGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEM 307
APGVDLT LLN+MRA+YE +AEQNR+DAEAWF EKS L+++IS + S+++E+ ++
Sbjct: 289 APGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDL 348
Query: 308 KRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQ 367
+R Q LEIELQS LA K SLE SL E E +YCAQL+Q+Q I LE QL QVR + E Q
Sbjct: 349 RRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQ 408
Query: 368 KLEYEQLLDIKVHLEKEIETYCLLIDGE---DG-----SCSKSKGYGGPGNQTKDSSKTT 419
+++++LL++K LE EIETY L+DGE DG + SK + +KD +KT
Sbjct: 409 NVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTR 468
Query: 420 IVKTVVEEIDPRGKVLSSRVHTVEE 444
+KTVV+E+ G+V+SS+V +EE
Sbjct: 469 KIKTVVQEM-VNGEVVSSQVQEIEE 492
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 427 bits (1098), Expect = e-119
Identities = 245/474 (51%), Positives = 318/474 (67%), Gaps = 35/474 (7%)
Query: 2 SVRFSSTSRRLGSCG-----GTGSVRLSSGGAG--------FGAG--------NTCGVPG 40
S +F+S+S GSCG G GS R+SS AG +G G ++ G G
Sbjct: 5 SRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYG 64
Query: 41 IGSGFSCAFGGSSSA------GGYGGGLGGGSASC--AAFTGNEHGLLSGNEKVTMQNLN 92
+G G+ F SSS+ GGYGGGLG G F G + GLL G+EKVTMQNLN
Sbjct: 65 LGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGD-GLLVGSEKVTMQNLN 123
Query: 93 DRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISA 152
DRLASYL+ VRALEEANADLE KI+ WY++ P + DYS YF I++L+N+I++A
Sbjct: 124 DRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIK----DYSPYFKTIEDLRNKILTA 179
Query: 153 TTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQL 212
T NA+V+LQ DNARL ADDFR K+E EL L SVEADINGLRRVLDELTL R DLE+Q+
Sbjct: 180 TVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQI 239
Query: 213 ETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNR 272
E+L EELAYLKKNHEEEM AL+ GG+VNVEM+AAPGVDL+ +LN MR +YE +AE+NR
Sbjct: 240 ESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNR 299
Query: 273 RDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSL 332
+DAE WF K+ L ++++ ++ S ++E+ E++RT+Q LEIELQS L+ K SLE SL
Sbjct: 300 KDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSL 359
Query: 333 TETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLI 392
ET+ YC QLAQIQ IG++EEQL Q+R E E Q EY+ LLD+K LE+EI TY L+
Sbjct: 360 EETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLL 419
Query: 393 DGEDGSCSKSKGYGGPGNQTKDSSKTTIVKTVVEEIDPRGKVLSSRVHTVEEKS 446
+GED S S+ G + +S + ++T V ++ GKV+S+ + K+
Sbjct: 420 EGEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHD-GKVVSTHEQVLRTKN 472
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 421 bits (1082), Expect = e-118
Identities = 238/439 (54%), Positives = 303/439 (69%), Gaps = 25/439 (5%)
Query: 4 RFSSTSRRLGSCG-GTGSVRLS---SGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYG 59
+F+S+S GS G G GS R S SGG G G+ G+GS GGSS + Y
Sbjct: 7 QFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGS----TLGGSSYSSCYS 62
Query: 60 GGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGW 119
G GGG S G GLL+G EK TMQNLNDRLASYL+ VRALEEAN +LE KI+ W
Sbjct: 63 FGSGGGYGSSF---GGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDW 119
Query: 120 YEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFEN 179
Y++ PG R DYS+Y+ I+EL+N+I++AT NA+++LQ DNARL ADDFR KFE
Sbjct: 120 YQRQAPGPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFET 175
Query: 180 ELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGG 239
E AL SVEADINGLRRVLDELTL R DLE+Q+E L EELAYLKKNHEEEM AL+ GG
Sbjct: 176 EQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGG 235
Query: 240 NVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTS 299
+NVEM+AAPGVDL+ +LN MR +YE +AE+NR+DAE WF K+ L ++++ ++ S
Sbjct: 236 EINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQS 295
Query: 300 ARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQ 359
++E+ E++RT+Q LEIELQS L+ K SLE +L ETE+ YC QL+QIQ IG++EEQL Q
Sbjct: 296 GKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQ 355
Query: 360 VRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGNQTKDSSKTT 419
+R E E Q EY+ LLD+K LE+EI TY L++GED ++ K K+ T
Sbjct: 356 LRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYK---------KEPVTTR 406
Query: 420 IVKTVVEEIDPRGKVLSSR 438
V+T+VEE+ GKV+SSR
Sbjct: 407 QVRTIVEEVQD-GKVISSR 424
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 421 bits (1082), Expect = e-118
Identities = 238/436 (54%), Positives = 298/436 (68%), Gaps = 36/436 (8%)
Query: 2 SVRFSSTSRRLGSCG-----GTGSVRLSSGGAG------------------FGAGNTCGV 38
S +F+S+S GSCG G GS R+SS AG F +G CG+
Sbjct: 5 SRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGL 64
Query: 39 PG-IGSGFSCAFG-GSSSAGGYGGGLGGG------SASCAAFTGNEHGLLSGNEKVTMQN 90
G G GFS + GS GGYGGGLG G + F G + GLL G+EKVTMQN
Sbjct: 65 GGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGD-GLLVGSEKVTMQN 123
Query: 91 LNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQII 150
LNDRLASYL+ VRALEEANADLE KI+ WY++ P + DYS YF I++L+N+II
Sbjct: 124 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIK----DYSPYFKTIEDLRNKII 179
Query: 151 SATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEI 210
+AT NA +LQ DNARL ADDFR K+E+ELAL Q+VEAD+NGLRRVLDELTL RTDLE+
Sbjct: 180 AATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEM 239
Query: 211 QLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQ 270
Q+E L EELAYL+KNHEEEM AL+ GG+VNVEM+AAPGVDL+ +LN MR +YE +AE+
Sbjct: 240 QIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK 299
Query: 271 NRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLEC 330
NRRDAE WF K+ L ++++ ++ S+R+E+ E++R LQ LEIELQS L+ K SLE
Sbjct: 300 NRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLEN 359
Query: 331 SLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCL 390
SL ET+ YC QL+QIQ IG++EEQL Q+R E E Q EY+ LLD+K LE+EI TY
Sbjct: 360 SLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRR 419
Query: 391 LIDGEDGSCSKSKGYG 406
L++GED S + G
Sbjct: 420 LLEGEDAHLSSQQASG 435
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 418 bits (1074), Expect = e-117
Identities = 240/444 (54%), Positives = 302/444 (68%), Gaps = 30/444 (6%)
Query: 1 MSVRFSSTSRRLG------SC---GGTG----SVRLSSGGA--GFGAGNTCGVPG-IGSG 44
MS+R S+S G SC GG G S R SGG+ G+G G +CG G GSG
Sbjct: 1 MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60
Query: 45 FSCAFGGSSSAGGYGGGLGGGSASCAA-----FTGNEHGLLSGNEKVTMQNLNDRLASYL 99
F +GG GGYGGGLGGG A F + GLL+GNEK+TMQNLNDRLASYL
Sbjct: 61 FGGGYGGGLG-GGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYL 119
Query: 100 ENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHV 159
E VRALEEANADLE KI+ W+ K P S + DYS Y+ I+EL+++I++AT N V
Sbjct: 120 EKVRALEEANADLEVKIRDWHLKQSPASP---ERDYSPYYKTIEELRDKILTATIENNRV 176
Query: 160 VLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEEL 219
+L+ DNARL ADDFRLK+ENELAL QSVEADINGLRRVLDELTL +TDLE+Q+E+L+EEL
Sbjct: 177 ILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEEL 236
Query: 220 AYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWF 279
AY+KKNHEEEMK G VNVEM+A PG+DLT +L MR +YEA+AE+NRRDAE WF
Sbjct: 237 AYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWF 296
Query: 280 NEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNY 339
+ KSA L +++S + +++ E+ E++RTLQ LEIELQS L+ K LE ++ ETE Y
Sbjct: 297 HAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRY 356
Query: 340 CAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSC 399
QL QIQ I ++E QL ++R+E E Q EY+ LLDIK LE+EI TY L++G+D
Sbjct: 357 ALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQD--- 413
Query: 400 SKSKGYGGPGNQTKDSSKTTIVKT 423
+K G P + S ++T V T
Sbjct: 414 --AKMIGFPSSAGSVSPRSTSVTT 435
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 415 bits (1067), Expect = e-116
Identities = 240/466 (51%), Positives = 298/466 (63%), Gaps = 44/466 (9%)
Query: 1 MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCG---------------VPGIGSGF 45
M+ F TS G T L +GG GFG G+ G G G G+
Sbjct: 1 MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGY 60
Query: 46 S-----CAFGGSSSA---GGYGGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLAS 97
C FGG + + GG+GGG+GGG F G + GLLSGNEK+TMQNLNDRLAS
Sbjct: 61 GGGMRVCGFGGGAGSVFGGGFGGGVGGGFGG--GFGGGDGGLLSGNEKITMQNLNDRLAS 118
Query: 98 YLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNA 157
YL+ VRALEEANADLE KI WY+K P S + DYS+YF I+EL+++I++ T N+
Sbjct: 119 YLDKVRALEEANADLEVKIHDWYQKQTPTSP---ECDYSQYFKTIEELRDKIMATTIDNS 175
Query: 158 HVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSE 217
V+L+ DNARL ADDFRLK+ENELAL Q VEADINGLRRVLDELTL RTDLE+Q+E L+E
Sbjct: 176 RVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNE 235
Query: 218 ELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEA 277
ELAYLKKNHEEEMK G VNVEM+AAPGVDLT +L MR +YEA+AE+NRRD EA
Sbjct: 236 ELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEA 295
Query: 278 WFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETES 337
WF K+ L ++++ + +++ E+ +++RT+Q LEIELQS L+ K LE SL ETE
Sbjct: 296 WFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETEC 355
Query: 338 NYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED- 396
Y QL QIQ IG LE QL ++R E E Q EY+ LLDIK LE+EI TY L++G+D
Sbjct: 356 RYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDA 415
Query: 397 -----GSCSKSKGYGGPGNQTKDSSKTTIVKTVVEEIDPRGKVLSS 437
G S G GG S + V E +D G+V+SS
Sbjct: 416 KMAGIGIREASSGGGG--------SSSNFHINVEESVD--GQVVSS 451
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 415 bits (1066), Expect = e-116
Identities = 233/417 (55%), Positives = 291/417 (69%), Gaps = 25/417 (5%)
Query: 1 MSVRFSSTSRRLG------SC---GGTG----SVRLSSGGA--GFGAGNTCGVPG-IGSG 44
MS+R S+S G SC GG G S R SGG+ G+G G +CG G GSG
Sbjct: 1 MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60
Query: 45 FSCAFGGSSSAGGYGGGLGGGSASCAA-----FTGNEHGLLSGNEKVTMQNLNDRLASYL 99
F +GG GGYGGGLGGG A F + GLL+GNEK+TMQNLNDRLASYL
Sbjct: 61 FGGGYGGGLG-GGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYL 119
Query: 100 ENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHV 159
E VRALEEANADLE KI+ W+ K P S + DYS Y+ I+EL+++I++AT N V
Sbjct: 120 EKVRALEEANADLEVKIRDWHLKQSPASP---ERDYSPYYKTIEELRDKILTATIENNRV 176
Query: 160 VLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEEL 219
+L+ DNARL ADDFRLK+ENELAL QSVEADINGLRRVLDELTL +TDLE+Q+E+L+EEL
Sbjct: 177 ILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEEL 236
Query: 220 AYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWF 279
AY+KKNHEEEMK G VNVEM+A PG+DLT +L MR +YEA+AE+NRRDAE WF
Sbjct: 237 AYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWF 296
Query: 280 NEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNY 339
+ KSA L +++S + +++ E+ E++RTLQ LEIELQS L+ K LE ++ ETE Y
Sbjct: 297 HAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRY 356
Query: 340 CAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
QL QIQ I ++E QL ++R+E E Q EY+ LLDIK LE+EI TY L++G+D
Sbjct: 357 ALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQD 413
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 387 bits (993), Expect = e-107
Identities = 214/396 (54%), Positives = 275/396 (69%), Gaps = 13/396 (3%)
Query: 2 SVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCA-FGGSSSAGGYGG 60
S R SS + G GG GSVR G A G G G S A F SSS+G YGG
Sbjct: 5 SYRQSSATSSFGGLGG-GSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGG 63
Query: 61 GLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY 120
G GG T ++ GLL+GNEK+TMQNLNDRLASYL+ VRALE AN +LE KI+ WY
Sbjct: 64 GYGG------VLTASD-GLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWY 116
Query: 121 EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE 180
+K GPG R DYS Y+ I +L+++I+ AT N+ +VLQ DNARL ADDFR KFE E
Sbjct: 117 QKQGPGPSR----DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETE 172
Query: 181 LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN 240
AL SVEADINGLRRVLDELTL RTDLE+Q+E L EELAYLKKNHEEE+ L+ GG
Sbjct: 173 QALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQ 232
Query: 241 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA 300
V+VE+++APG DL +L++MR++YE +AEQNR+DAEAWF ++ L ++++ +
Sbjct: 233 VSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMS 292
Query: 301 RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 360
R+E+ +++RTLQ LEIELQS L+ K +LE +L ETE+ + AQLA IQA I +E QL V
Sbjct: 293 RSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDV 352
Query: 361 RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
R ++E Q EY++L+DIK LE+EI TY L++G++
Sbjct: 353 RADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 342 bits (877), Expect = 4e-94
Identities = 195/409 (47%), Positives = 249/409 (60%), Gaps = 23/409 (5%)
Query: 5 FSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGG 64
F SR G G G G GFG G+ G G G+ FGG GG+GGG GG
Sbjct: 90 FGGGSRGFGGASGGGYSSSGGFGGGFGGGSG---GGFGGGYGSGFGGF---GGFGGGAGG 143
Query: 65 GSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFG 124
G G+L+ NEK TMQ LN RLASYL+ V+ALEEAN DLE KI+ WY+K G
Sbjct: 144 GDG----------GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKG 193
Query: 125 PGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALH 184
P + + +YS Y+ ID+LK+QI+ T N +L DN R+T DDFR+KFE E L
Sbjct: 194 PAA---IQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLR 250
Query: 185 QSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVE 244
Q V+ADINGLR+VLD LT+ ++DLE+Q ETL EEL LKKNH+EEM L G+VNVE
Sbjct: 251 QGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVE 310
Query: 245 MNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNEL 304
+N APG DLT LN+MR EYE L +NR+D E + + ++ ++S S+ E+
Sbjct: 311 INVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEV 370
Query: 305 IEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTET 364
+++ +Q LEIELQS L+ K +LE SL +T++ YC QL IQ QI LE Q+ VR E
Sbjct: 371 TQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEI 430
Query: 365 EGQKLEYEQLLDIKVHLEKEIETYCLLIDGE----DGSCSKSKGYGGPG 409
E Q EY LL IK+ LEKEIETY L++G + S + G GG G
Sbjct: 431 ECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRG 479
Score = 45.8 bits (107), Expect = 8e-05
Identities = 34/71 (47%), Positives = 38/71 (53%), Gaps = 5/71 (7%)
Query: 16 GGTGSVRLSSGG--AGFGAGNTCGVPGIGSGFSCAF--GGSSSAGGYGGGLGGGSASCAA 71
GG+GS S GG G G G++ G G SG S GGS S GG GGG GGGS S
Sbjct: 522 GGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGG 581
Query: 72 FTGNEHGLLSG 82
+G HG SG
Sbjct: 582 -SGGSHGGGSG 591
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/54 (53%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGS 66
GS GG+G GG+G G G G G GSG S GGS S GG GGG GGGS
Sbjct: 488 GSRGGSGG-SYGGGGSGGGYGGGSGSRG-GSGGSYG-GGSGSGGGSGGGYGGGS 538
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/58 (46%), Positives = 32/58 (55%), Gaps = 7/58 (12%)
Query: 16 GGTGSVRLSSGGAGFGAGNTCGVPGI---GSGFSC----AFGGSSSAGGYGGGLGGGS 66
GG+GS S GG G G+G+ G G GSGF ++GG A G GGG GGGS
Sbjct: 560 GGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGS 617
Score = 42.7 bits (99), Expect = 7e-04
Identities = 31/71 (43%), Positives = 36/71 (50%), Gaps = 8/71 (11%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
GS GG GS GG G G+G+ G G G S + GG S GGYGGG GGG + +
Sbjct: 495 GSYGGGGS----GGGYGGGSGSRGGSGGSYGGGSGSGGG--SGGGYGGGSGGGHSGGSG- 547
Query: 73 TGNEHGLLSGN 83
G G GN
Sbjct: 548 -GGHSGGSGGN 557
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/76 (36%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSA-GGYGGGLGGGSASCAA 71
G GG S G +G GN G G G G +GG S + GG GG GGGS
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGS----G 591
Query: 72 FTGNEHGLLSGNEKVT 87
F G G G E+ +
Sbjct: 592 FGGESGGSYGGGEEAS 607
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/66 (42%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
GS GG+G G+G G+G G G G G S GG S GG GG GGGS S
Sbjct: 511 GSRGGSGGSYGGGSGSGGGSGGGYG-GGSGGGHSGGSGGGHS-GGSGGNYGGGSGSGGGS 568
Query: 73 TGNEHG 78
G G
Sbjct: 569 GGGYGG 574
Score = 37.7 bits (86), Expect = 0.022
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 9/79 (11%)
Query: 13 GSCGGTGSVRLSSGGAG--FGAGNTCGVPGIGSGFSCAFGGS---SSAGGYGGGLG---G 64
GS GG G S GG+G +G G+ G G G G+ GG S GG+ GG G G
Sbjct: 501 GSGGGYGGGSGSRGGSGGSYGGGSGSG-GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYG 559
Query: 65 GSASCAAFTGNEHGLLSGN 83
G + +G +G SG+
Sbjct: 560 GGSGSGGGSGGGYGGGSGS 578
Score = 36.2 bits (82), Expect = 0.064
Identities = 27/66 (40%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAF 72
GS G G S GG+G G G G G GSG S GG S GG GG GG +
Sbjct: 553 GSGGNYGGGSGSGGGSGGGYGGGSGSRG-GSGGS--HGGGSGFGGESGGSYGGGEEASGS 609
Query: 73 TGNEHG 78
G G
Sbjct: 610 GGGYGG 615
Score = 35.0 bits (79), Expect = 0.14
Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 13 GSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAG-GYGGGLGG--GSASC 69
G GG+G GG+G G G+ G G GSG GGS G G+GG GG G
Sbjct: 549 GHSGGSGGNY--GGGSGSGGGSGGGYGG-GSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605
Query: 70 AAFTGNEHGLLSG 82
A+ +G +G SG
Sbjct: 606 ASGSGGGYGGGSG 618
Score = 34.7 bits (78), Expect = 0.19
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 6 SSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYG-GGLGG 64
SS + ++G G GS G+ G+G + G G G G+ G +GG GG G
Sbjct: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS 526
Query: 65 GSASCAAFTGNEHGLLSG 82
G S + G G SG
Sbjct: 527 GGGSGGGYGGGSGGGHSG 544
Score = 30.4 bits (67), Expect = 3.5
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Query: 24 SSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAG-GYGGGLGGGSASCAAFTGNEHGLLSG 82
SSG G G G G S G S G G GGG GGGS S +G +G SG
Sbjct: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG-SGGSYGGGSG 525
Query: 83 N 83
+
Sbjct: 526 S 526
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 340 bits (871), Expect = 2e-93
Identities = 189/389 (48%), Positives = 251/389 (64%), Gaps = 17/389 (4%)
Query: 11 RLGSCGGTGSVRLSS--GGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGG-LGGGSA 67
R+ S GS R+ S G AG+ + G+ G+GS C G S+ + G +G G
Sbjct: 27 RVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGS---CLPGSYLSSECHTSGFVGSGGW 83
Query: 68 SCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGS 127
C G +G+EK TMQ LNDRLA+YLE VR LE NA+LE +I+ WYE P
Sbjct: 84 FC-------EGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYI 136
Query: 128 CRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSV 187
C DY YF I++ + +I+ + NA +VLQ DNA+L ADDFR K+E EL+L Q V
Sbjct: 137 CP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLV 192
Query: 188 EADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNA 247
EADINGLRR+LDELTLC+ DLE Q+E+L EEL LKKNHEEE+ L+C G +NVE++A
Sbjct: 193 EADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDA 252
Query: 248 APGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEM 307
AP VDL +L +MR +YEAL E NRRD EAWFN ++ L QQ+ + + E+IE+
Sbjct: 253 APPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIEL 312
Query: 308 KRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQ 367
+RT+ LEIELQ+ + ++SLE +L ETE+ Y +QLAQ+Q I +E QL ++R + E Q
Sbjct: 313 RRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQ 372
Query: 368 KLEYEQLLDIKVHLEKEIETYCLLIDGED 396
EY+ LLD+K LE EI TY L++GED
Sbjct: 373 NQEYQVLLDVKARLEGEIATYRHLLEGED 401
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 329 bits (843), Expect = 4e-90
Identities = 192/412 (46%), Positives = 260/412 (63%), Gaps = 19/412 (4%)
Query: 33 GNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLN 92
G T V G G S YG L GG L GNEK+ MQNLN
Sbjct: 30 GTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGGG-----------DLFVGNEKMAMQNLN 78
Query: 93 DRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISA 152
DRLASYLE VR LE++N+ LE +IK WYE P + R DYS Y+ I+EL++QI A
Sbjct: 79 DRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGR----DYSAYYRQIEELRSQIKDA 134
Query: 153 TTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQL 212
NA VLQ DNA+L A+DFRLK+E E + +VEAD+ GL +V D+LTL +TDLEIQ+
Sbjct: 135 QLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQI 194
Query: 213 ETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNR 272
E L+++LA LKK H+EE+ L G VNVE++AAPG++L V++N MR +YE +A++N
Sbjct: 195 EELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNL 254
Query: 273 RDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSL 332
++A+ F ++A LQQQ++ + +L E++RT Q+LEIELQS L+ K SLE +L
Sbjct: 255 QEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTL 314
Query: 333 TETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLI 392
ET++ Y +QLA +Q+ + +LE QL Q+R+ E Q EY LLDIK LE+EI TY L+
Sbjct: 315 EETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLL 374
Query: 393 DGEDGSCSKSKGYGGPGNQTKDSSKTTIVKTVVEEIDPRGKVLSSRVHTVEE 444
+GED K+ Y + +D KT +KTVV+E+ GKV+SS V VEE
Sbjct: 375 EGED---VKTTEYQLSTLEERDIKKTRKIKTVVQEV-VDGKVVSSEVKEVEE 422
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 322 bits (825), Expect = 4e-88
Identities = 183/410 (44%), Positives = 254/410 (61%), Gaps = 32/410 (7%)
Query: 5 FSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIG----SGFSCAFG-GSSS----- 54
FSS S + GS R+S+ + ++C +P + S +C+ G G SS
Sbjct: 10 FSSGSLKSPGGASGGSTRVSA----MYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATS 65
Query: 55 --------AGGYGGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALE 106
AGG+ GG G+L+GNEK TMQ+LNDRLA YLE VR LE
Sbjct: 66 CLPALCLPAGGFATSYSGGGGWFG------EGILTGNEKETMQSLNDRLAGYLEKVRQLE 119
Query: 107 EANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNA 166
+ NA LE +I+ W E+ P C DY YF I+EL+ + + + NA +V++ DNA
Sbjct: 120 QENASLESRIREWCEQQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNA 175
Query: 167 RLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNH 226
+L ADDFR K+E E++L Q VE+DINGLRR+LD+LTLC++DLE Q+E+L EEL LKKNH
Sbjct: 176 KLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNH 235
Query: 227 EEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASL 286
EEE+ +L+C G +NVE++AAP VDL +L MR +YE L E NRRDAE W + +S L
Sbjct: 236 EEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEEL 295
Query: 287 QQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQI 346
QQ+ + S + E+IE++RT+ LEIELQ+ + + +LE +L ETE+ Y +QLAQ+
Sbjct: 296 NQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQM 355
Query: 347 QAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
Q I +E QL ++R + E Q EY+ LLD++ LE EI TY L++ ED
Sbjct: 356 QCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESED 405
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 310 bits (795), Expect = 1e-84
Identities = 164/343 (47%), Positives = 228/343 (66%), Gaps = 11/343 (3%)
Query: 54 SAGGYGGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLE 113
+A G G +G GS G +GNEK TMQ LNDRLASYL VR LE+ NA+LE
Sbjct: 73 AASGISGSMGPGS-------WYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELE 125
Query: 114 QKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDF 173
+I ++ + DY +F I+EL+ +I+ NA +V+ DNA+L ADDF
Sbjct: 126 SRI----QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDF 181
Query: 174 RLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKAL 233
R K+E ELA+ Q VEADINGLRR+LD+LTLC+ DLE Q+E+L EEL LKKNHEEE+ +L
Sbjct: 182 RAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSL 241
Query: 234 QCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDD 293
+C G +N+E++AAP VDLT +L MR +YEA+ E NRRD E WFN + L QQ++
Sbjct: 242 RCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATS 301
Query: 294 AGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGAL 353
+ + ++++I+++RT+ TLEIELQ+ + + SLE +LTE+E+ Y +QLAQ+Q I +
Sbjct: 302 SEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNV 361
Query: 354 EEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
E QL ++R + E Q EY+ LLD++ LE EI TY L++ ED
Sbjct: 362 EAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENED 404
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 306 bits (783), Expect = 3e-83
Identities = 172/387 (44%), Positives = 242/387 (62%), Gaps = 24/387 (6%)
Query: 35 TCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGS------ASCAAFTGNEHGLLSGNEKVTM 88
+CG+P + SC+ +G L G ++C F G +G+EK TM
Sbjct: 4 SCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFC---EGSFNGSEKETM 60
Query: 89 QNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQ 148
Q LNDRLASYLE VR LE NA+LE I+ ++ P C Y YF I+EL+ +
Sbjct: 61 QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCAS----YQSYFKTIEELQQK 116
Query: 149 IISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDL 208
I+ + + NA +V+Q DNA+L +DDFR K+E EL+L Q VE+DINGLRR+LDELTLCR+DL
Sbjct: 117 ILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDL 176
Query: 209 EIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALA 268
E Q+E+L EEL LK+NHE+E+ L+C G +NVE++AAP VDL +LN R++YEAL
Sbjct: 177 EAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALV 236
Query: 269 EQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSL 328
E NRR+ E WF ++ L +Q+ + S + E+IE++RT+ LEIELQ+ + SL
Sbjct: 237 ETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSL 296
Query: 329 ECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETY 388
E +LTE+E+ Y +QL+Q+Q I +E QL ++R++ E Q EY+ LLD++ LE EI TY
Sbjct: 297 ENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTY 356
Query: 389 CLLIDGED-----------GSCSKSKG 404
L++ ED +C KS G
Sbjct: 357 RSLLESEDCKLPSNPCATTNACDKSTG 383
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 300 bits (767), Expect = 2e-81
Identities = 157/319 (49%), Positives = 219/319 (68%), Gaps = 4/319 (1%)
Query: 78 GLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 137
G +G+EK TMQ LNDRLASYLE VR LE NA+LE I+ ++ P C Y
Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105
Query: 138 YFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRV 197
YF I+EL+ +I+ + NA +V+Q DNA+L ADDFR K++ EL+L Q VE+DINGLRR+
Sbjct: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165
Query: 198 LDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLL 257
LDELTLC++DLE Q+E+L EEL LK NHE+E+ L+C G +NVE++AAP VDL +L
Sbjct: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225
Query: 258 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIE 317
N R++YEAL E NRR+ E WF ++ L +Q+ + S + E+IE++RT+ LEIE
Sbjct: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
Query: 318 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 377
LQ+ + SLE +LTE+E+ Y +QL+Q+Q+ I +E QL ++R++ E Q EY+ LLD+
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345
Query: 378 KVHLEKEIETYCLLIDGED 396
+ LE EI TY L++ ED
Sbjct: 346 RARLECEINTYRSLLESED 364
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 298 bits (762), Expect = 9e-81
Identities = 156/319 (48%), Positives = 219/319 (68%), Gaps = 4/319 (1%)
Query: 78 GLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 137
G +G+EK TMQ LNDRLASYLE VR LE NA+LE I+ ++ P C Y
Sbjct: 50 GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105
Query: 138 YFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRV 197
YF I+EL+ +I+ + + NA +V+Q DNA+L ADDFR K++ E +L Q VE+DIN LRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRI 165
Query: 198 LDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLL 257
LDELTLCR+DLE Q+E+L EEL LK+NHE+E+ L+C G +NVE++AAP VDL +L
Sbjct: 166 LDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVL 225
Query: 258 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIE 317
N R +YEAL E NRR+ E WF ++ L +Q+ + S + E+IE++RT+ LEIE
Sbjct: 226 NETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
Query: 318 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 377
LQ+ ++SLE +LTE+E+ Y +QL+Q+Q+ I +E QL ++R++ E Q EY+ LLD+
Sbjct: 286 LQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345
Query: 378 KVHLEKEIETYCLLIDGED 396
+ LE EI TY L++ ED
Sbjct: 346 RARLECEINTYRSLLESED 364
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 288 bits (738), Expect = 5e-78
Identities = 162/368 (44%), Positives = 232/368 (63%), Gaps = 13/368 (3%)
Query: 35 TCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGS------ASCAAFTGNEHGLLSGNEKVTM 88
+C +P +G SC+ +G L G ++C F G +G+EK TM
Sbjct: 46 SCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFC---EGSFNGSEKETM 102
Query: 89 QNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQ 148
Q LNDRLASYLE VR LE NA+LE+ I+ ++ P C Y YF I+EL+ +
Sbjct: 103 QFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPS----YQSYFKTIEELQQK 158
Query: 149 IISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDL 208
I+ A NA +V+ DNA+L +DDFR K++ E +L VE+DIN +RR+LDELTLC++DL
Sbjct: 159 ILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDL 218
Query: 209 EIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALA 268
E Q+E+L EEL LKKNHEEE+ L+ G +NVE++ AP VDL +LN R++YEAL
Sbjct: 219 ESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALV 278
Query: 269 EQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSL 328
E NRR+ E WF ++ L +Q+ + S + E+IE++RT+ LEIELQ+ + SL
Sbjct: 279 EINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSL 338
Query: 329 ECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETY 388
E +LTE+E++Y +QL+Q+Q+ I +E QL ++R + E Q EY+ LLD++ LE EI TY
Sbjct: 339 ENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTY 398
Query: 389 CLLIDGED 396
L++ ED
Sbjct: 399 RSLLESED 406
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 286 bits (732), Expect = 3e-77
Identities = 161/358 (44%), Positives = 222/358 (62%), Gaps = 13/358 (3%)
Query: 65 GSASCAAFTGN----EHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY 120
GS + GN E G+ + NEK TMQ LNDRLASYLE VR+LEE NA+LE +I+
Sbjct: 66 GSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQC 125
Query: 121 EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE 180
E+ P C DY RYF I++L+ +I+ N+ + +Q DN +L DDF+ K+E+E
Sbjct: 126 EQDIPMVCP----DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESE 181
Query: 181 LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN 240
L+L Q +EADI+ L +L+ELTLC++DLE +E+L E+L LKKNHEEE+ L+ G
Sbjct: 182 LSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDR 241
Query: 241 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA 300
++VE++ AP +DL +L+ MR + E + NRR+AE W ++ L QQ A
Sbjct: 242 LSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGC 301
Query: 301 RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 360
+ E++E+KRT LEIELQ+ + SLEC++ ETE+ Y +QLAQIQ I LE QL ++
Sbjct: 302 QMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEI 361
Query: 361 RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGNQTKDSSKT 418
R + E Q EY+ LLD+K LE EI TY L+D ED S S P + T SS T
Sbjct: 362 RCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCS-----PCSTTCTSSNT 414
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 284 bits (727), Expect = 1e-76
Identities = 171/432 (39%), Positives = 249/432 (57%), Gaps = 40/432 (9%)
Query: 41 IGSGFSCAFGGSSSAGGYGGGLG---------------GGSASCAAFT------------ 73
+ SG S + S+S G GGG G GG+ +FT
Sbjct: 1 MNSGHSFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWG 60
Query: 74 -GNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLD 132
G LL GN K TMQNLNDRLASYLE VRALEEAN LE +I W+++ PGS +
Sbjct: 61 SGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKK--- 117
Query: 133 HDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADIN 192
DYS+Y I L+ QI+ +NA ++L DNAR+ DDF LK+ENE + + +E ++
Sbjct: 118 -DYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVE 176
Query: 193 GLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVD 252
GLRR LD LT+ TDLE ++E + +EL +KK+HE+EM+ + NVNV+++ P D
Sbjct: 177 GLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPRED 236
Query: 253 LTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQ 312
L +L +MR EYE + ++ RD + W+ E+SA++ Q+ + A S + ++ E+KRT Q
Sbjct: 237 LIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQ 295
Query: 313 TLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYE 372
LEI+LQ+ +TK +LE L+ET+S Y +L +Q I EE+L Q+R E E Q EY+
Sbjct: 296 ALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQ 355
Query: 373 QLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGNQTKDSSKTTIVKTVVEEIDPRG 432
LL IK HLEKEI TY L++GE S+G + S T +K + +E G
Sbjct: 356 VLLGIKTHLEKEITTYRRLLEGE------SEGTREESKSSMKVSATPKIKAITQE-TING 408
Query: 433 KVLSSRVHTVEE 444
+++ +V+ +++
Sbjct: 409 RLVLCQVNEIQK 420
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 281 bits (718), Expect = 1e-75
Identities = 184/448 (41%), Positives = 249/448 (55%), Gaps = 32/448 (7%)
Query: 5 FSSTSRRLGSCGGTG-SVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLG 63
FS+ R LGS R S A AG I S +F G +GG G+
Sbjct: 9 FSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIA 68
Query: 64 GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKF 123
GG A NEK TMQ+LNDRLASYL+ VR+LE N LE KI+ EK
Sbjct: 69 GGLAGMGGIQ---------NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKK 119
Query: 124 GPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183
GP D+S YF II++L+ QI + T NA +VLQ DNARL ADDFR+K+E ELA+
Sbjct: 120 GPQV-----RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAM 174
Query: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQC-AAGGNVN 242
QSVE DI+GLR+V+D+ + R LE ++E L EEL ++KKNHEEE+K LQ A +
Sbjct: 175 RQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLT 234
Query: 243 VEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARN 302
VE++A DL ++ ++RA+Y+ LA +NR + + +++++ ++ + +A
Sbjct: 235 VEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAET 294
Query: 303 ELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRT 362
L E++RT+Q+LEI+L S+ K SLE SL E E+ Y Q+ Q+ + LE +L Q R
Sbjct: 295 TLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRA 354
Query: 363 ETEGQKLEYEQLLDIKVHLEKEIETY-CLLIDGEDGSCSKSKGYGGPGNQTKDSSKTTIV 421
E + Q EYE LL+IKV LE EI TY LL DGED + + +S TI
Sbjct: 355 EGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDA--------LDSSNSMQTIQ 406
Query: 422 KTVVEEIDPRGKVLSSRVHTVEEKSTKV 449
KT I GKV+S E TKV
Sbjct: 407 KTTTRRI-VDGKVVS------ETNDTKV 427
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 281 bits (718), Expect = 1e-75
Identities = 184/448 (41%), Positives = 249/448 (55%), Gaps = 32/448 (7%)
Query: 5 FSSTSRRLGSCGGTG-SVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLG 63
FS+ R LGS R S A AG I S +F G +GG G+
Sbjct: 9 FSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIA 68
Query: 64 GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKF 123
GG A NEK TMQ+LNDRLASYL+ VR+LE N LE KI+ EK
Sbjct: 69 GGLAGMGGIQ---------NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKK 119
Query: 124 GPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183
GP D+S YF II++L+ QI + T NA +VLQ DNARL ADDFR+K+E ELA+
Sbjct: 120 GPQV-----RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAM 174
Query: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQC-AAGGNVN 242
QSVE DI+GLR+V+D+ + R LE ++E L EEL ++KKNHEEE+K LQ A +
Sbjct: 175 RQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLT 234
Query: 243 VEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARN 302
VE++A DL ++ ++RA+Y+ LA +NR + + +++++ ++ + +A
Sbjct: 235 VEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAET 294
Query: 303 ELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRT 362
L E++RT+Q+LEI+L S+ K SLE SL E E+ Y Q+ Q+ + LE +L Q R
Sbjct: 295 TLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRA 354
Query: 363 ETEGQKLEYEQLLDIKVHLEKEIETY-CLLIDGEDGSCSKSKGYGGPGNQTKDSSKTTIV 421
E + Q EYE LL+IKV LE EI TY LL DGED + + +S TI
Sbjct: 355 EGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDA--------LDSSNSMQTIQ 406
Query: 422 KTVVEEIDPRGKVLSSRVHTVEEKSTKV 449
KT I GKV+S E TKV
Sbjct: 407 KTTTRRI-VDGKVVS------ETNDTKV 427
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 276 bits (706), Expect = 3e-74
Identities = 147/318 (46%), Positives = 204/318 (64%), Gaps = 4/318 (1%)
Query: 80 LSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYF 139
++ NEK TMQ LN+RLA+YL+ VR LE NA+LE KI+ K P C DY Y+
Sbjct: 92 INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147
Query: 140 PIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLD 199
I+EL+ +I+ N+ +V Q DN +LTADD R K+E E++L Q VE+D NGL+++L+
Sbjct: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207
Query: 200 ELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNN 259
LTL + DLE Q+++L EEL LK NH+EE+ +LQC G +++E+ AAP DL +L
Sbjct: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267
Query: 260 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQ 319
MR +YE + E NR+D E WFN + L QQ+ + + E+IE++R++ TLE+ELQ
Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
Query: 320 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKV 379
+ + S EC LTETE+ Y A L QIQ+ I LE QL ++R E Q EYE LLD+K
Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
Query: 380 HLEKEIETYCLLIDGEDG 397
LE EI TY L++ DG
Sbjct: 388 RLECEITTYRSLLESSDG 405
>gi|55770882 keratin 37 [Homo sapiens]
Length = 449
Score = 256 bits (655), Expect = 2e-68
Identities = 141/333 (42%), Positives = 202/333 (60%), Gaps = 7/333 (2%)
Query: 64 GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKF 123
G C A+ N L+G+EK TM+ LNDRLA+YLE VR LE+ NA+LE + +
Sbjct: 87 GNIGICGAYGKNT---LNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCH 143
Query: 124 GPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183
C DY YF I+EL+ +I+ + NA +++Q DNA+L ADDFR+K E+E +L
Sbjct: 144 ESTVCP----DYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSL 199
Query: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNV 243
HQ VEAD G +++LD+ TL + DLE Q E+L EE LK NHE+E+K L+ G +
Sbjct: 200 HQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRI 259
Query: 244 EMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNE 303
E++ P +DL +L MRA+YEA+ E N +D E WF +S + Q + ++E
Sbjct: 260 ELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSE 319
Query: 304 LIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTE 363
++E++ T+ LE+E Q+ K L+ SL E E Y +LAQ+Q+ I LEEQL ++R +
Sbjct: 320 ILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRAD 379
Query: 364 TEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
E Q EY+ LLD+K LE EI TY L++ ED
Sbjct: 380 LERQNQEYQVLLDVKARLENEIATYRNLLESED 412
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 254 bits (648), Expect = 1e-67
Identities = 140/333 (42%), Positives = 203/333 (60%), Gaps = 7/333 (2%)
Query: 64 GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKF 123
G C A+ N L+G+EK TMQ LNDRLA+YLE VR LE+ NA+LE + +
Sbjct: 87 GNIGICGAYGENT---LNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCH 143
Query: 124 GPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183
C DY YF I+EL+ +I+ + NA +++Q DNA+L ADDFR+K E+E +L
Sbjct: 144 ESTVCP----DYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSL 199
Query: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNV 243
Q VEAD G +++LD+ TL + DLE Q E+L EE LK NHE+E+K L+ G + +
Sbjct: 200 RQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRI 259
Query: 244 EMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNE 303
E++ P +DL +L MRA+YEA+ E NR+D E WF +S + Q + ++E
Sbjct: 260 ELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSE 319
Query: 304 LIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTE 363
++E++ T+ LE+E Q+ K L+ SL E E + +LAQ+Q+ I +EEQL ++R +
Sbjct: 320 ILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRAD 379
Query: 364 TEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
E Q EY+ LLD+K LE EI TY L++ ED
Sbjct: 380 LERQNQEYQVLLDVKTRLENEIATYRNLLESED 412
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,820,468
Number of Sequences: 37866
Number of extensions: 788041
Number of successful extensions: 9327
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 445
Number of HSP's that attempted gapping in prelim test: 4411
Number of HSP's gapped (non-prelim): 2872
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.