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Search of human proteins with 153792633
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792633 hypothetical protein LOC26049 [Homo sapiens]
(670 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792633 hypothetical protein LOC26049 [Homo sapiens] 1325 0.0
gi|110624768 hypothetical protein LOC283777 [Homo sapiens] 102 9e-22
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 60 7e-09
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 60 7e-09
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 57 7e-08
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 57 7e-08
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 54 6e-07
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 54 6e-07
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 54 6e-07
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 54 6e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 52 1e-06
gi|157738619 smoothelin-like 1 [Homo sapiens] 52 2e-06
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 51 3e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 50 5e-06
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 50 7e-06
gi|157694505 LINE-1 type transposase domain containing 1 [Homo s... 50 7e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 50 7e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 50 9e-06
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 48 3e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 48 3e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 48 3e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 48 3e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 48 3e-05
gi|38261962 activating transcription factor 7 interacting protei... 47 4e-05
gi|21264343 scaffold attachment factor B [Homo sapiens] 47 6e-05
gi|24308179 CTTNBP2 N-terminal like [Homo sapiens] 46 1e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 46 1e-04
gi|190194423 SPARC-like 1 [Homo sapiens] 46 1e-04
gi|190341024 SPARC-like 1 [Homo sapiens] 46 1e-04
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 45 2e-04
>gi|153792633 hypothetical protein LOC26049 [Homo sapiens]
Length = 670
Score = 1325 bits (3430), Expect = 0.0
Identities = 670/670 (100%), Positives = 670/670 (100%)
Query: 1 MAFPVDMLENCSHEELENSAEDYMSDLRCGDPENPECFSLLNITIPISLSNVGFVPLYGG 60
MAFPVDMLENCSHEELENSAEDYMSDLRCGDPENPECFSLLNITIPISLSNVGFVPLYGG
Sbjct: 1 MAFPVDMLENCSHEELENSAEDYMSDLRCGDPENPECFSLLNITIPISLSNVGFVPLYGG 60
Query: 61 DQTQKILALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVSTLGERVVLYVLN 120
DQTQKILALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVSTLGERVVLYVLN
Sbjct: 61 DQTQKILALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVSTLGERVVLYVLN 120
Query: 121 RIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSICASFLTQSYQLPVL 180
RIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSICASFLTQSYQLPVL
Sbjct: 121 RIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSICASFLTQSYQLPVL 180
Query: 181 DTMFLRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLSSLMYTACKQYFEKYPGDHELLW 240
DTMFLRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLSSLMYTACKQYFEKYPGDHELLW
Sbjct: 181 DTMFLRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLSSLMYTACKQYFEKYPGDHELLW 240
Query: 241 EVEGVGHWYQRIPVTRALQREALKILALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSE 300
EVEGVGHWYQRIPVTRALQREALKILALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSE
Sbjct: 241 EVEGVGHWYQRIPVTRALQREALKILALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSE 300
Query: 301 MQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQT 360
MQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQT
Sbjct: 301 MQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQT 360
Query: 361 SLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEK 420
SLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEK
Sbjct: 361 SLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEK 420
Query: 421 ESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKP 480
ESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKP
Sbjct: 421 ESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKP 480
Query: 481 PEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSD 540
PEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSD
Sbjct: 481 PEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSD 540
Query: 541 GGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVP 600
GGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVP
Sbjct: 541 GGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVP 600
Query: 601 FSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHK 660
FSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHK
Sbjct: 601 FSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHK 660
Query: 661 GPAKKKAKLT 670
GPAKKKAKLT
Sbjct: 661 GPAKKKAKLT 670
>gi|110624768 hypothetical protein LOC283777 [Homo sapiens]
Length = 192
Score = 102 bits (255), Expect = 9e-22
Identities = 56/135 (41%), Positives = 84/135 (62%), Gaps = 10/135 (7%)
Query: 106 QVSTLGERVVLYVLNRIIYRKQE--MERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPT 163
+V + GERVVL++LN II+ + E ++ +++ FL HS + AKILW++G A+GFY+ K
Sbjct: 2 KVQSFGERVVLFILNAIIFGRLERNLDDDDMFFLPHSVKEQAKILWRRGAAVGFYTTKMK 61
Query: 164 GSICASFLTQSYQLPVLDTMFLRKKYRGKDFGLHMLEDFVDSFTED-ALGLRYPLSSLMY 222
G +C Y LPV DT+F+R+K+ + G ML DF ++F ED ALG+ +S MY
Sbjct: 62 GRLCGDGTGACYLLPVFDTVFIRRKHWHRGLGTAMLRDFCETFPEDEALGVSCSMSPAMY 121
Query: 223 TACKQYFEKYPGDHE 237
A +PG+ E
Sbjct: 122 QA-------HPGNSE 129
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 60.1 bits (144), Expect = 7e-09
Identities = 83/377 (22%), Positives = 149/377 (39%), Gaps = 36/377 (9%)
Query: 312 FASTSEGHDKTSVSTHTRSGNLKRPKIGK-------RFQDSEFSSSQGEDEKTSQTSLTA 364
FA + G T T S +++PK+ +F + ++ EDEK+
Sbjct: 415 FAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALT 474
Query: 365 SINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESEL 424
+I + + + E E E+E E E E+E P T P+ ++++GEKE E
Sbjct: 475 AITEELAVSMKEEKKEAAEEKEEEP---EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEE 531
Query: 425 EPMNGEIMDDSLKTSLI-----------------TEEEDSTSEVLDEELKLQPFNSSEDS 467
E D+ K+ EE ++ +E EE + + E+
Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 591
Query: 468 TNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSD-EKGHMEEK-LSLLPRKKAHLG 525
+ V E +V+ P+K + ++G S K +EEK S +P+
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651
Query: 526 SSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLE-DQGEEGVSEPQETST 584
V EE+ S + E ++ PV ++ S E +GE+ E +E
Sbjct: 652 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 711
Query: 585 ALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEV 644
A P+ +E + E+ P +K +S + EA +E + T+S + ++ ++E E
Sbjct: 712 A-PKEEKVE-KKEEKPKDVPEKKKAESPVKEEAVAEVV-TITKSVKVHLEKETKE---EG 765
Query: 645 PVVDRRNLRRKAKGHKG 661
+ + + KA G G
Sbjct: 766 KPLQQEKEKEKAGGEGG 782
Score = 51.6 bits (122), Expect = 2e-06
Identities = 78/334 (23%), Positives = 127/334 (38%), Gaps = 57/334 (17%)
Query: 343 QDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRD 402
Q+ E S E+ + L + +LES ES E L + E+ D SS +D
Sbjct: 305 QNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHN---HDLSSYQD 361
Query: 403 ARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVL--DEELKLQP 460
LE + + K + + D L + + E + L EE +
Sbjct: 362 TIQQLENELRGTKWEMARHLRE-------YQDLLNVKMALDIEIAAYRKLLEGEETRFST 414
Query: 461 FNSSEDS---TNLVPLVVESS-KPPEVDAPD-KTPRIPDSEMLMDEGTSDEKGHMEEKLS 515
F S T+ P+ + S + P+V+AP K E++ + DEK MEE L+
Sbjct: 415 FAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALT 474
Query: 516 LLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEG 575
+ ++ +A EE+ + E EE V+ SP ++ E + EEG
Sbjct: 475 AI---------TEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 525
Query: 576 VSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDS 635
E +E GQ+ + EE A S+Q ++ +EK S
Sbjct: 526 EKEEEE------------------------GQEEEEEEDEGAKSDQAEE--GGSEKEGSS 559
Query: 636 SSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKL 669
EE E E +A+G + AK++ K+
Sbjct: 560 EKEEGEQE-----EGETEAEAEGEEAEAKEEKKV 588
Score = 32.3 bits (72), Expect = 1.5
Identities = 38/172 (22%), Positives = 65/172 (37%), Gaps = 14/172 (8%)
Query: 323 SVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEF 382
SV H + K ++ ++ E + +G E+ K + +E
Sbjct: 752 SVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEE 811
Query: 383 LEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESE-------LEPMNGEIMDDS 435
+E+E +++G E+E L+ P EK+ G+K E +E + E D +
Sbjct: 812 VEQETKEKGSGREEEKG--VVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGA 869
Query: 436 LKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPD 487
T IT+ T +V + E + F ST V V + EV D
Sbjct: 870 --TKYITKSVTVTQKVEEHE---ETFEEKLVSTKKVEKVTSHAIVKEVTQSD 916
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 60.1 bits (144), Expect = 7e-09
Identities = 83/377 (22%), Positives = 149/377 (39%), Gaps = 36/377 (9%)
Query: 312 FASTSEGHDKTSVSTHTRSGNLKRPKIGK-------RFQDSEFSSSQGEDEKTSQTSLTA 364
FA + G T T S +++PK+ +F + ++ EDEK+
Sbjct: 39 FAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALT 98
Query: 365 SINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESEL 424
+I + + + E E E+E E E E+E P T P+ ++++GEKE E
Sbjct: 99 AITEELAVSMKEEKKEAAEEKEEEP---EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEE 155
Query: 425 EPMNGEIMDDSLKTSLI-----------------TEEEDSTSEVLDEELKLQPFNSSEDS 467
E D+ K+ EE ++ +E EE + + E+
Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 215
Query: 468 TNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSD-EKGHMEEK-LSLLPRKKAHLG 525
+ V E +V+ P+K + ++G S K +EEK S +P+
Sbjct: 216 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275
Query: 526 SSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLE-DQGEEGVSEPQETST 584
V EE+ S + E ++ PV ++ S E +GE+ E +E
Sbjct: 276 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 335
Query: 585 ALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEV 644
A P+ +E + E+ P +K +S + EA +E + T+S + ++ ++E E
Sbjct: 336 A-PKEEKVE-KKEEKPKDVPEKKKAESPVKEEAVAEVV-TITKSVKVHLEKETKE---EG 389
Query: 645 PVVDRRNLRRKAKGHKG 661
+ + + KA G G
Sbjct: 390 KPLQQEKEKEKAGGEGG 406
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 42/204 (20%)
Query: 468 TNLVPLVVESS-KPPEVDAPD-KTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLG 525
T+ P+ + S + P+V+AP K E++ + DEK MEE L+ +
Sbjct: 49 THRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAI-------- 100
Query: 526 SSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTA 585
++ +A EE+ + E EE V+ SP ++ E + EEG E +E
Sbjct: 101 -TEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEE---- 155
Query: 586 LPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVP 645
GQ+ + EE A S+Q ++ +EK S EE E E
Sbjct: 156 --------------------GQEEEEEEDEGAKSDQAEE--GGSEKEGSSEKEEGEQE-- 191
Query: 646 VVDRRNLRRKAKGHKGPAKKKAKL 669
+A+G + AK++ K+
Sbjct: 192 ---EGETEAEAEGEEAEAKEEKKV 212
Score = 32.3 bits (72), Expect = 1.5
Identities = 38/172 (22%), Positives = 65/172 (37%), Gaps = 14/172 (8%)
Query: 323 SVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEF 382
SV H + K ++ ++ E + +G E+ K + +E
Sbjct: 376 SVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEE 435
Query: 383 LEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESE-------LEPMNGEIMDDS 435
+E+E +++G E+E L+ P EK+ G+K E +E + E D +
Sbjct: 436 VEQETKEKGSGREEEKG--VVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGA 493
Query: 436 LKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPD 487
T IT+ T +V + E + F ST V V + EV D
Sbjct: 494 --TKYITKSVTVTQKVEEHE---ETFEEKLVSTKKVEKVTSHAIVKEVTQSD 540
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 56.6 bits (135), Expect = 7e-08
Identities = 78/338 (23%), Positives = 127/338 (37%), Gaps = 21/338 (6%)
Query: 343 QDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQR--GIEFEDESSD 400
Q SE S+ QG+D TS + ++ + E + E E E+ G + ESS
Sbjct: 145 QASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSH 204
Query: 401 RDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEE------EDSTSEVLDE 454
D E + + D + E N + +K+ E +DS L E
Sbjct: 205 GDGS---ELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLE 261
Query: 455 ELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEE-- 512
+ F S S ++ + E D T + + + D KG +E
Sbjct: 262 HPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDS 321
Query: 513 KLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPN---TTSSLE 569
K +L + ++ D ++ S++E + NS +E EE VSE+ N TTS +E
Sbjct: 322 KENLSQEESQNV---DGPSSESSQEANLSSQENS--SESQEEVVSESRGDNPDPTTSYVE 376
Query: 570 DQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSA 629
DQ + SE + T S E D S++ +S E E + + QS
Sbjct: 377 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSH 436
Query: 630 EKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKA 667
+ +S SEE E D ++ R + K +
Sbjct: 437 SSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSS 474
Score = 42.0 bits (97), Expect = 0.002
Identities = 76/354 (21%), Positives = 134/354 (37%), Gaps = 50/354 (14%)
Query: 275 RPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSV--------ST 326
R + E S PE T++++S E + S D +S +G + S
Sbjct: 166 RELDNEDRVDSKPEGGDSTQESESEEHWVGGGS--DGESSHGDGSELDDEGMQSDDPESI 223
Query: 327 HTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEE 386
+ GN + G + ++S +S Q + + + L ++ R S SEE E
Sbjct: 224 RSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSR--KIFRKSRISEEDDRSE 281
Query: 387 PEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEED 446
+ E +S + + +T Q ++D + +S+ +DS K +L EE
Sbjct: 282 LDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQ---------EDS-KENLSQEESQ 331
Query: 447 STSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDE 506
+ E + +S E+S+ VV S+ D PD P + + D+ SD
Sbjct: 332 NVDGPSSESSQEANLSSQENSSESQEEVVSESRG---DNPD-----PTTSYVEDQEDSDS 383
Query: 507 KGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTS 566
E+ L K+ S EE++D S+ FSEE SP +
Sbjct: 384 SE--EDSSHTLSHSKSE----------SREEQADSESSESL--NFSEE------SPESPE 423
Query: 567 SLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSE 620
+EG+ ++ + + S E + D S + + + S E +S E
Sbjct: 424 DENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 477
Score = 40.0 bits (92), Expect = 0.007
Identities = 54/230 (23%), Positives = 103/230 (44%), Gaps = 32/230 (13%)
Query: 293 TEDNQSSEMQ--LTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSS 350
+E++ SE+ T++ +K S D T +R G +DS+ + S
Sbjct: 274 SEEDDRSELDDNNTMEEVKSDSTENSNSRD-------TGLSQPRRDSKGDSQEDSKENLS 326
Query: 351 QGE----DEKTSQTSLTASINKLESTARPSESSEEFLEEE----PEQRGIEFED-ESSDR 401
Q E D +S++S A+++ E++ SES EE + E P+ ED E SD
Sbjct: 327 QEESQNVDGPSSESSQEANLSSQENS---SESQEEVVSESRGDNPDPTTSYVEDQEDSDS 383
Query: 402 DARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPF 461
+ T + + E++++ E + E ++ S ++ E+E+S+S+ LQ
Sbjct: 384 SEEDSSHTLSHSKSESREEQADSE--SSESLNFSEESPESPEDENSSSQE-----GLQSH 436
Query: 462 NSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHME 511
+SS +S + S+ + D+ D + DS + +S+E G ++
Sbjct: 437 SSSAESQS----EESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLK 482
Score = 38.5 bits (88), Expect = 0.020
Identities = 60/258 (23%), Positives = 98/258 (37%), Gaps = 23/258 (8%)
Query: 396 DESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEE 455
DE SD + + E+ PQ + + SE ++ E DS E DST E EE
Sbjct: 137 DEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSK-----PEGGDSTQESESEE 191
Query: 456 LKLQPFNSSE----DSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDE-GTSDEKGHM 510
+ + E D + L ++S P + + R+ + M E G + E+ +
Sbjct: 192 HWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANT 251
Query: 511 EEK--LSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSL 568
++ LL + ++ + D N+ + E + + S +T S
Sbjct: 252 QDSGGSQLLEHPSRKIFRKSRISEEDDRSELD---DNNTMEEVKSDSTENSNSRDTGLSQ 308
Query: 569 EDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNA---GQKNQSEEQSEASSEQL--- 622
+ +G S+ +++ L Q V+ SQ A Q+N SE Q E SE
Sbjct: 309 PRRDSKGDSQ-EDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDN 367
Query: 623 -DQFTQSAEKAVDSSSEE 639
D T E DS S E
Sbjct: 368 PDPTTSYVEDQEDSDSSE 385
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 56.6 bits (135), Expect = 7e-08
Identities = 78/338 (23%), Positives = 127/338 (37%), Gaps = 21/338 (6%)
Query: 343 QDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQR--GIEFEDESSD 400
Q SE S+ QG+D TS + ++ + E + E E E+ G + ESS
Sbjct: 129 QASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSH 188
Query: 401 RDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEE------EDSTSEVLDE 454
D E + + D + E N + +K+ E +DS L E
Sbjct: 189 GDGS---ELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLE 245
Query: 455 ELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEE-- 512
+ F S S ++ + E D T + + + D KG +E
Sbjct: 246 HPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDS 305
Query: 513 KLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPN---TTSSLE 569
K +L + ++ D ++ S++E + NS +E EE VSE+ N TTS +E
Sbjct: 306 KENLSQEESQNV---DGPSSESSQEANLSSQENS--SESQEEVVSESRGDNPDPTTSYVE 360
Query: 570 DQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSA 629
DQ + SE + T S E D S++ +S E E + + QS
Sbjct: 361 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSH 420
Query: 630 EKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKA 667
+ +S SEE E D ++ R + K +
Sbjct: 421 SSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSS 458
Score = 42.0 bits (97), Expect = 0.002
Identities = 76/354 (21%), Positives = 134/354 (37%), Gaps = 50/354 (14%)
Query: 275 RPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSV--------ST 326
R + E S PE T++++S E + S D +S +G + S
Sbjct: 150 RELDNEDRVDSKPEGGDSTQESESEEHWVGGGS--DGESSHGDGSELDDEGMQSDDPESI 207
Query: 327 HTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEE 386
+ GN + G + ++S +S Q + + + L ++ R S SEE E
Sbjct: 208 RSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSR--KIFRKSRISEEDDRSE 265
Query: 387 PEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEED 446
+ E +S + + +T Q ++D + +S+ +DS K +L EE
Sbjct: 266 LDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQ---------EDS-KENLSQEESQ 315
Query: 447 STSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDE 506
+ E + +S E+S+ VV S+ D PD P + + D+ SD
Sbjct: 316 NVDGPSSESSQEANLSSQENSSESQEEVVSESRG---DNPD-----PTTSYVEDQEDSDS 367
Query: 507 KGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTS 566
E+ L K+ S EE++D S+ FSEE SP +
Sbjct: 368 SE--EDSSHTLSHSKSE----------SREEQADSESSESL--NFSEE------SPESPE 407
Query: 567 SLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSE 620
+EG+ ++ + + S E + D S + + + S E +S E
Sbjct: 408 DENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 461
Score = 40.0 bits (92), Expect = 0.007
Identities = 54/230 (23%), Positives = 103/230 (44%), Gaps = 32/230 (13%)
Query: 293 TEDNQSSEMQ--LTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSS 350
+E++ SE+ T++ +K S D T +R G +DS+ + S
Sbjct: 258 SEEDDRSELDDNNTMEEVKSDSTENSNSRD-------TGLSQPRRDSKGDSQEDSKENLS 310
Query: 351 QGE----DEKTSQTSLTASINKLESTARPSESSEEFLEEE----PEQRGIEFED-ESSDR 401
Q E D +S++S A+++ E++ SES EE + E P+ ED E SD
Sbjct: 311 QEESQNVDGPSSESSQEANLSSQENS---SESQEEVVSESRGDNPDPTTSYVEDQEDSDS 367
Query: 402 DARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPF 461
+ T + + E++++ E + E ++ S ++ E+E+S+S+ LQ
Sbjct: 368 SEEDSSHTLSHSKSESREEQADSE--SSESLNFSEESPESPEDENSSSQE-----GLQSH 420
Query: 462 NSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHME 511
+SS +S + S+ + D+ D + DS + +S+E G ++
Sbjct: 421 SSSAESQS----EESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLK 466
Score = 38.5 bits (88), Expect = 0.020
Identities = 60/258 (23%), Positives = 98/258 (37%), Gaps = 23/258 (8%)
Query: 396 DESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEE 455
DE SD + + E+ PQ + + SE ++ E DS E DST E EE
Sbjct: 121 DEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSK-----PEGGDSTQESESEE 175
Query: 456 LKLQPFNSSE----DSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDE-GTSDEKGHM 510
+ + E D + L ++S P + + R+ + M E G + E+ +
Sbjct: 176 HWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANT 235
Query: 511 EEK--LSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSL 568
++ LL + ++ + D N+ + E + + S +T S
Sbjct: 236 QDSGGSQLLEHPSRKIFRKSRISEEDDRSELD---DNNTMEEVKSDSTENSNSRDTGLSQ 292
Query: 569 EDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNA---GQKNQSEEQSEASSEQL--- 622
+ +G S+ +++ L Q V+ SQ A Q+N SE Q E SE
Sbjct: 293 PRRDSKGDSQ-EDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDN 351
Query: 623 -DQFTQSAEKAVDSSSEE 639
D T E DS S E
Sbjct: 352 PDPTTSYVEDQEDSDSSE 369
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 53.5 bits (127), Expect = 6e-07
Identities = 69/350 (19%), Positives = 129/350 (36%), Gaps = 16/350 (4%)
Query: 294 EDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGE 353
+DN S+ D+ +S S +S S+ + S + DS+ S S
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD------SNSSSDSDSSDSDSS 588
Query: 354 DEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQ 413
D S +S +++ + ++ S+SS+ + + + E +SSD D++
Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Query: 414 EKQDGEKESELE-PMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVP 472
+ D S+ N DS +S + DS++ D NSSE S +
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS-DSSDSSDSSNSSESSDSS-- 705
Query: 473 LVVESSKPPEVDAPDKT-PRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVA 531
+SS D+ D + DS+ +SD + S + S + +
Sbjct: 706 ---DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762
Query: 532 TMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTS--SLEDQGEEGVSEPQETSTALPQS 589
S+ S +S + S+ S N S ++ S S + S+ ++S + +
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Query: 590 SLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEE 639
S D S N+ + S + S+ S + S+ + S S +
Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872
Score = 53.1 bits (126), Expect = 8e-07
Identities = 62/369 (16%), Positives = 131/369 (35%), Gaps = 14/369 (3%)
Query: 269 SQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHT 328
S N S + S + R++ + SS+ + DS + +S S +++S S+ +
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894
Query: 329 RSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE 388
+ +S SS +S++S ++ + ++ S+SS+
Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS------- 947
Query: 389 QRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDST 448
D S+ D+ + ++ + D + N DS +S ++ DS+
Sbjct: 948 ------SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 449 -SEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEK 507
S + ++S DS+N S D+ D + S+ +SD
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 508 GHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSS 567
+ S + S + S+ S +S ++ S+ S + S ++ SS
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 568 LEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQ 627
+ + ++ S E D S ++ + S + S++S +
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Query: 628 SAEKAVDSS 636
+ + DSS
Sbjct: 1182 DSSDSSDSS 1190
Score = 51.2 bits (121), Expect = 3e-06
Identities = 57/348 (16%), Positives = 126/348 (36%), Gaps = 11/348 (3%)
Query: 293 TEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQG 352
++ + SS+ + DS + + +S S +S S + S N DS SS+
Sbjct: 871 SDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930
Query: 353 EDEKTSQTSLTASINKLESTARPSESSEEF----LEEEPEQRGIEFEDESSDRDARPALE 408
++ +S +S ++ + ++ S+SS + + + D S+ D+ + +
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Query: 409 TQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDST 468
+ + D S+ + + S + + ++S+ D +SS+ S
Sbjct: 991 SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050
Query: 469 NLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSD 528
+ S D+ D + S+ +SD + S + S
Sbjct: 1051 S-------SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 529 NVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQ 588
+ + S+ S +S ++ S+ S + S ++ SS E + ++
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163
Query: 589 SSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS 636
S + D S N+ + S + S++S + + + DSS
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211
Score = 50.8 bits (120), Expect = 4e-06
Identities = 71/368 (19%), Positives = 134/368 (36%), Gaps = 18/368 (4%)
Query: 278 SGEYGPASVPEYEARTEDNQSSEMQLT---IDSLKDAFASTSEGHDKTSVSTHTRSGNLK 334
S G AS E++ N S DS D S S G+ + +S + K
Sbjct: 485 SSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK 544
Query: 335 RPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEF 394
K DS SS+ + +S + + S + +S + S+SS+ +
Sbjct: 545 G-KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS--SDSDSSDSSNS 601
Query: 395 EDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDE 454
D S D+ + ++ + + +SE + + + DS ++ ++S S
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 455 ELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKT--PRIPDSEMLMDEGTSDEKGHMEE 512
+ S DS++ S+ D+ D + DS D +SD
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 513 KLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSS-LEDQ 571
S + +S + + SN S +S ++ S+ S N S ++ SS D
Sbjct: 722 NSS-----DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 572 GEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEK 631
+ S S+ SS + + S N+ + S + S++ S + S++
Sbjct: 777 SDSSNSSDSNDSSNSSDSS----DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832
Query: 632 AVDSSSEE 639
+ S+S +
Sbjct: 833 SDSSNSSD 840
Score = 50.8 bits (120), Expect = 4e-06
Identities = 63/344 (18%), Positives = 123/344 (35%), Gaps = 9/344 (2%)
Query: 293 TEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQG 352
++ + SS+ + DS D+ S S+ D S S + S N DS SS+
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS-NSSDSSDNSDSSDSSNSSNSS 666
Query: 353 EDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQ 412
+ +S +S ++S + +++ S+SS+ E + +SSD +
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 413 QEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVP 472
+ + DS +S ++ DS++ + + S DS+N
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS--SDSSDSSDSSDSSDSSNSSD 784
Query: 473 LVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVAT 532
S+ D+ + + S+ +SD S SSD+ +
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Query: 533 MSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLI 592
+ + SD N + S + + S N++ S + S+ E+S + S
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS------SDSNESSNSSDSSDSS 898
Query: 593 EVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS 636
D S N+ + S S++S ++ + +SS
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Score = 50.4 bits (119), Expect = 5e-06
Identities = 62/346 (17%), Positives = 127/346 (36%), Gaps = 15/346 (4%)
Query: 293 TEDNQSSEMQLTIDSLKDAFAS-TSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQ 351
++ + SS+ + DS + +S +S+ D + S + S N DS SS+
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800
Query: 352 GEDEKTSQTSLTASINKLEST-ARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQ 410
+ +S +S ++ + +S+ + S +S + + + D S D+ + +
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860
Query: 411 PQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNL 470
+ + DS ++S ++ DS++ + + S DS+N
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN- 919
Query: 471 VPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNV 530
SS E DS D S + + + + + S N
Sbjct: 920 ------SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 531 ATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSS 590
+ S+ S +S ++ S+ S N S ++ SS D + S S+ SS
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS--DSSDSSNSSDSSNSSDSSNSS 1031
Query: 591 LIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS 636
+ D S ++ + S + S++S+ + + + DSS
Sbjct: 1032 ----DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073
Score = 50.4 bits (119), Expect = 5e-06
Identities = 60/348 (17%), Positives = 130/348 (37%), Gaps = 5/348 (1%)
Query: 293 TEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQG 352
++ N+SS + DS + + +S+ + + S + S + +S SS+
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 353 EDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDR-DARPALETQP 411
+ +S +S ++ + ++ S+SS+ + + +SSD D+ + ++
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 412 QQEKQDGEKESELE-PMNGEIMDDSLKTSLITEEEDST--SEVLDEELKLQPFNSSEDST 468
+ D S+ + DS +S ++ DS+ S+ D NSS DS+
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSS 1061
Query: 469 NLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSD 528
+ S D+ D + S+ +SD + S + S
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 529 NVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQ 588
N + S+ S +S ++ S+ S + S ++ SS + + ++
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Query: 589 SSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS 636
S + D S ++ + S + S++S + + + DSS
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Score = 50.4 bits (119), Expect = 5e-06
Identities = 61/344 (17%), Positives = 126/344 (36%), Gaps = 11/344 (3%)
Query: 293 TEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQG 352
+E + SS+ + DS + +S S +S S+++ + DS SS+
Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 353 EDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQ 412
+ +S +S ++ + +++ S+SS+ + D S+ D+ + ++
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSS-DSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 413 QEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVP 472
+ D S+ N DS +S ++ DS+ E + S DS+N
Sbjct: 1043 SDSSDSSDSSDSS--NSSDSSDSSDSSDSSDSSDSSDSSDSSES-----SDSSDSSNSSD 1095
Query: 473 LVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVAT 532
S D+ D + S+ +SD + S + S +
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS---SNSSDSSDSSESSD 1152
Query: 533 MSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLI 592
S+ S +S ++ S+ S N S ++ SS + + ++ S
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212
Query: 593 EVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS 636
+ D S ++ + S E S++S + ++ + DSS
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS 1256
Score = 49.7 bits (117), Expect = 9e-06
Identities = 61/353 (17%), Positives = 131/353 (37%), Gaps = 12/353 (3%)
Query: 293 TEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQG 352
++ + SS+ + DS + +S S D + S + S + DS SS
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 353 EDEKTSQTSLTASINKLESTARPSESSE--EFLEEEPEQRGIEFEDESSDRDARPALETQ 410
+ +S +S ++ + ++ S+SS+ + + + D S+ D+ + ++
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 411 PQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNL 470
+ D S+ + E D S ++ + S S + + S DS+N
Sbjct: 1068 DSSDSSDSSDSSD----SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 471 VPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNV 530
S D+ + + SE +SD + S + +S +
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183
Query: 531 ATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSS 590
+ S+ S +S ++ S+ S + S ++ SS D + S S+ SS
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSNESSDSSDSS 1241
Query: 591 LIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVE 643
+ D S ++ + S + + S+++ D ++S + S + + E
Sbjct: 1242 ----DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290
Score = 48.5 bits (114), Expect = 2e-05
Identities = 66/356 (18%), Positives = 125/356 (35%), Gaps = 24/356 (6%)
Query: 285 SVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQD 344
S + ++ D+ S + DS + +S S +S S+ + K D
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635
Query: 345 SEFSS-SQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDA 403
S+ S S + S + +S + S + S S + + D S D+
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Query: 404 RPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNS 463
+ E+ + D + + N D S + + ++S+ D
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD---------- 745
Query: 464 SEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAH 523
S DS+N S D+ D + S+ ++D + S ++
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Query: 524 LGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETS 583
S + + S+ + S+ +S + S+ S N S ++ SS G + S + S
Sbjct: 806 SSDSSDSSDSSDSDSSN----SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861
Query: 584 TALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEA--SSEQLDQFTQSAEKAVDSSS 637
+ SS D S N+ + S + +E+ SS+ D S + DSS+
Sbjct: 862 SNSSDSS-------DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910
Score = 47.8 bits (112), Expect = 3e-05
Identities = 61/348 (17%), Positives = 120/348 (34%), Gaps = 15/348 (4%)
Query: 293 TEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSS--S 350
++ + SS+ + DS + + +S D ++ S + S + DS SS S
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 351 QGEDEKTSQTSLTASINKLESTARPSESSE--EFLEEEPEQRGIEFEDESSDRDARPALE 408
D S S ++ + ++ S SS+ E + + S D+ +
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 409 TQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDST 468
+ D S+ N DS +S ++ DS+ + S DS+
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS-----------SDSSDSS 1001
Query: 469 NLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSD 528
N S ++ D + S +SD + S ++ S
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 529 NVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQ 588
+ + S+ S +S +E S+ S N S ++ SS + + ++
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 589 SSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS 636
+S + D S ++ + S + SE+S + + + DSS
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Score = 46.6 bits (109), Expect = 7e-05
Identities = 61/363 (16%), Positives = 130/363 (35%), Gaps = 10/363 (2%)
Query: 278 SGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPK 337
S E +S + + D+ SS+ + DS + ++S+ + ++ S ++ S +
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS--NSSDSSESSNSSDNSNSSDSSNSS 942
Query: 338 IGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDE 397
DS SS +S +S ++ N +S+ S +S + + + D
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS--DSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 398 SSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDST----SEVLD 453
S+ D+ + ++ D S+ N DS +S ++ DS+ S
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSS--NSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 454 EELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEK 513
+ + S DS++ S D+ + + S+ +SD +
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 514 LSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGE 573
S + S + + SN S +S ++ S+ S + S ++ SS
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 574 EGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAV 633
+ ++ S + D S ++ + S + S++S + + +
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 634 DSS 636
DSS
Sbjct: 1239 DSS 1241
Score = 46.2 bits (108), Expect = 1e-04
Identities = 61/344 (17%), Positives = 125/344 (36%), Gaps = 29/344 (8%)
Query: 293 TEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQG 352
++ + SS+ + DS + +S+ D ++ S + S + DS SS+
Sbjct: 735 SDSSNSSDSSDSSDSSNSS--DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 353 EDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQ 412
+ +S +S S N +S+ S + + D S+ D+ ++
Sbjct: 793 DSSDSSNSS--DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS---DSSDS 847
Query: 413 QEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVP 472
+ D + + + N DS +S ++ DS+ + NSS+ S
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD-------SNESSNSSDSS----- 895
Query: 473 LVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVAT 532
+SS + D+ D + S+ +S+ + S ++ S + +
Sbjct: 896 ---DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS---SDSSNSSDSSDSSD 949
Query: 533 MSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLI 592
SN S +S ++ S+ S++ + +S D + S S+ SS
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS-- 1007
Query: 593 EVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS 636
+ D S N+ + S + S +S + + + DSS
Sbjct: 1008 --DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Score = 41.6 bits (96), Expect = 0.002
Identities = 61/335 (18%), Positives = 118/335 (35%), Gaps = 12/335 (3%)
Query: 290 EARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSS 349
++ + D SS+ + DS + +S S +S S+ + + + S
Sbjct: 970 DSNSSD--SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027
Query: 350 SQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALET 409
S D S S +S + S + S +S + + + D S D+ + ++
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087
Query: 410 QPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTN 469
D S+ + DS +S ++ DS++ + + S DS+N
Sbjct: 1088 SDSSNSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSSNS--SDSSDSSDSSDSSDSSN 1140
Query: 470 LVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDN 529
S D+ D + S+ +SD + S + S +
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200
Query: 530 VATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQS 589
+ S+ S +S ++ S+ S++ N +S D + S S+ S
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDS--SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDS 1258
Query: 590 SLIEVELEDVPFSQN-AGQKNQSEEQSEASSEQLD 623
S + D SQ+ +G N + S++ SE D
Sbjct: 1259 SDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1293
Score = 34.3 bits (77), Expect = 0.38
Identities = 53/294 (18%), Positives = 98/294 (33%), Gaps = 22/294 (7%)
Query: 293 TEDNQSSEMQLTIDSLKDAFAS-TSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSS-- 349
++ + SS+ + DS + +S +S+ D ++ S + S + DS SS
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES 1084
Query: 350 SQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALET 409
S D S S +S + S + S S + + + D S D+ + ++
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 1144
Query: 410 QPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTN 469
E D S+ + + D S + + S S + + S DS++
Sbjct: 1145 SDSSESSDSSDSSD----SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200
Query: 470 LVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDN 529
S D+ D + S+ +SD + S + S +
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260
Query: 530 VATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETS 583
+ SN+E + S++ + N S D EG TS
Sbjct: 1261 STSDSNDE---------------SDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 53.5 bits (127), Expect = 6e-07
Identities = 66/333 (19%), Positives = 141/333 (42%), Gaps = 19/333 (5%)
Query: 349 SSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALE 408
+ +GE+E + + + A+ S + +E+ E +EEE E+ + E S+ + + E
Sbjct: 1236 AEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE 1295
Query: 409 TQPQQEKQDGEKESELEPMNGEIMDDS-LKTSLITE-EEDSTSEVLDEELKLQPF---NS 463
+P++E+ + ++ + + + DD L+++ E EE T E + EE +Q +
Sbjct: 1296 PEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDAN 1355
Query: 464 SEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKL------SLL 517
+ S + E+ E + P + +M E +E H +E+L +
Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEI 1415
Query: 518 PRKKAHLGSSDNVATMSNEERS--DGGFPN---SVIAEFSEEPVSENLSPNTTSSLEDQG 572
P + L + V +++ EE S +G + + ++ A + + ++ S +ED
Sbjct: 1416 PHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCH 1475
Query: 573 EEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKA 632
+ P + + P S+ V +VP + +G S EQ S+ + S
Sbjct: 1476 ASEHNSPISSVQSHPSQSVRSVSSPNVP-ALESGYTQISPEQGSLSAPSMQNMETSPMMD 1534
Query: 633 VDSSSEEIE--VEVPVVDRRNLRRKAKGHKGPA 663
V S S+ + V+ D ++ + ++ P+
Sbjct: 1535 VPSVSDHSQQVVDSGFSDLGSIESTTENYENPS 1567
Score = 38.5 bits (88), Expect = 0.020
Identities = 66/314 (21%), Positives = 109/314 (34%), Gaps = 47/314 (14%)
Query: 381 EFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEP-------MNGEIM- 432
E + E E FED S+R T E+++ E E+EL P + +++
Sbjct: 1036 ETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLR 1095
Query: 433 -DDSLKTSLITEEEDSTSEVLDEELKLQPF---------NSSEDSTNLVPLVVESSKPPE 482
S K EEED S+ D+ L+P NS + PL + P
Sbjct: 1096 CQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKG 1155
Query: 483 VD--------APDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPR--KKAHLGSSDNVAT 532
P + P S +M T + + E + +P+ +K + S+
Sbjct: 1156 KSRKPIHWKKRPGRKPGFKLSREIMPVST---QACVIEPIVSIPKAGRKPKIQESEETV- 1211
Query: 533 MSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLI 592
E + D P E E + + E + E+ S ++ S+
Sbjct: 1212 ---EPKEDMPLP-------EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSP 1261
Query: 593 EVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNL 652
E E ++ + + SEEQ ++ EQ Q E+ E+ E D +
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQ-----QELEEPEPEEEEDAAAETAQNDDHDA 1316
Query: 653 RRKAKGHKGPAKKK 666
+ GH KKK
Sbjct: 1317 DDEDDGHLESTKKK 1330
Score = 38.5 bits (88), Expect = 0.020
Identities = 69/301 (22%), Positives = 108/301 (35%), Gaps = 58/301 (19%)
Query: 366 INKLESTARPSESS---EEFLEEEPEQRGIEFEDESSDRDAR---------------PAL 407
I + E T P E EE EEE Q E +E + DA P
Sbjct: 1204 IQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPET 1263
Query: 408 ET-QPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSED 466
ET +P+ E+++ + E E L+ EEED+ +E N D
Sbjct: 1264 ETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQ--------NDDHD 1315
Query: 467 STNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGS 526
+ + +ES+K E++ E E +E G E L +K+
Sbjct: 1316 ADDEDDGHLESTKKKELE-----------EQPTREDVKEEPGVQESFLD-ANMQKSREKI 1363
Query: 527 SDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTAL 586
D T + E SV VSE ++ + ED + + +
Sbjct: 1364 KDKEETELDSEEEQPSHDTSV--------VSEQMAGSEDDHEEDSHTKEELIELKEEEEI 1415
Query: 587 PQSSLIEVELEDVPFSQNAGQKNQSE--------EQSEASSEQLDQFTQSAEKAVDSSSE 638
P S E++LE V Q+ Q+ SE E++ A+ + L +TQ+ E S E
Sbjct: 1416 PHS---ELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVE 1472
Query: 639 E 639
+
Sbjct: 1473 D 1473
Score = 36.6 bits (83), Expect = 0.077
Identities = 72/341 (21%), Positives = 125/341 (36%), Gaps = 61/341 (17%)
Query: 334 KRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFL---EEEPEQR 390
K K +RF D + E Q K E+T SEE L EE+P Q
Sbjct: 871 KNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQ- 929
Query: 391 GIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSE 450
D +P L P++ +G +EP G+ + + ++
Sbjct: 930 -----------DGKPDL---PKRRLSEG-----VEPWRGQ----------LKKSPEALKC 960
Query: 451 VLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHM 510
L E + P SE ++ ESS E + ++PR +L +K +
Sbjct: 961 RLTEGSERLPRRYSEGDRAVLRGFSESS---EEEEEPESPRSSSPPILTKPTLKRKKPFL 1017
Query: 511 EEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLED 570
+ + RK+ H SS T+S V+ E E+ SE P + E
Sbjct: 1018 HRRRRV--RKRKHHNSSVVTETISE--------TTEVLDEPFEDSDSERPMPRLEPTFEI 1067
Query: 571 QGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQ------ 624
EE E ++ + P+ + +DV Q++ ++ +E+ + S+ D
Sbjct: 1068 DEEE---EEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKP 1124
Query: 625 FTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKK 665
+ ++ V +S E + P L++K KG ++K
Sbjct: 1125 VSLLRKRDVKNSPLEPDTSTP------LKKKKGWPKGKSRK 1159
Score = 30.8 bits (68), Expect = 4.2
Identities = 62/246 (25%), Positives = 98/246 (39%), Gaps = 39/246 (15%)
Query: 436 LKTSLITEEEDSTSE--------VLDEELKLQPFNS-SEDSTNLVPLVVESSKPPEVDAP 486
+ S+++EEE+ +E + EL++ S S ++ VES K PEV AP
Sbjct: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
Query: 487 DKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRK-KAHLGSSDNVATMSNEERSDGGFPN 545
+ R+ + D ++ + + RK + G D+ + EE S P
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLL--EETSSA--PQ 896
Query: 546 SVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIE-VELEDVPFSQN 604
E E+ SE T S E Q+ LP+ L E VE P+
Sbjct: 897 EQYGECGEK--SEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVE----PW--- 947
Query: 605 AGQKNQSEEQSEA----SSEQLDQFTQSAEKAV-----DSSSEEIEVE------VPVVDR 649
GQ +S E + SE+L + ++AV +SS EE E E P++ +
Sbjct: 948 RGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTK 1007
Query: 650 RNLRRK 655
L+RK
Sbjct: 1008 PTLKRK 1013
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 53.5 bits (127), Expect = 6e-07
Identities = 66/333 (19%), Positives = 141/333 (42%), Gaps = 19/333 (5%)
Query: 349 SSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALE 408
+ +GE+E + + + A+ S + +E+ E +EEE E+ + E S+ + + E
Sbjct: 1236 AEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE 1295
Query: 409 TQPQQEKQDGEKESELEPMNGEIMDDS-LKTSLITE-EEDSTSEVLDEELKLQPF---NS 463
+P++E+ + ++ + + + DD L+++ E EE T E + EE +Q +
Sbjct: 1296 PEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDAN 1355
Query: 464 SEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKL------SLL 517
+ S + E+ E + P + +M E +E H +E+L +
Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEI 1415
Query: 518 PRKKAHLGSSDNVATMSNEERS--DGGFPN---SVIAEFSEEPVSENLSPNTTSSLEDQG 572
P + L + V +++ EE S +G + + ++ A + + ++ S +ED
Sbjct: 1416 PHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCH 1475
Query: 573 EEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKA 632
+ P + + P S+ V +VP + +G S EQ S+ + S
Sbjct: 1476 ASEHNSPISSVQSHPSQSVRSVSSPNVP-ALESGYTQISPEQGSLSAPSMQNMETSPMMD 1534
Query: 633 VDSSSEEIE--VEVPVVDRRNLRRKAKGHKGPA 663
V S S+ + V+ D ++ + ++ P+
Sbjct: 1535 VPSVSDHSQQVVDSGFSDLGSIESTTENYENPS 1567
Score = 38.5 bits (88), Expect = 0.020
Identities = 66/314 (21%), Positives = 109/314 (34%), Gaps = 47/314 (14%)
Query: 381 EFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEP-------MNGEIM- 432
E + E E FED S+R T E+++ E E+EL P + +++
Sbjct: 1036 ETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLR 1095
Query: 433 -DDSLKTSLITEEEDSTSEVLDEELKLQPF---------NSSEDSTNLVPLVVESSKPPE 482
S K EEED S+ D+ L+P NS + PL + P
Sbjct: 1096 CQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKG 1155
Query: 483 VD--------APDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPR--KKAHLGSSDNVAT 532
P + P S +M T + + E + +P+ +K + S+
Sbjct: 1156 KSRKPIHWKKRPGRKPGFKLSREIMPVST---QACVIEPIVSIPKAGRKPKIQESEETV- 1211
Query: 533 MSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLI 592
E + D P E E + + E + E+ S ++ S+
Sbjct: 1212 ---EPKEDMPLP-------EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSP 1261
Query: 593 EVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNL 652
E E ++ + + SEEQ ++ EQ Q E+ E+ E D +
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQ-----QELEEPEPEEEEDAAAETAQNDDHDA 1316
Query: 653 RRKAKGHKGPAKKK 666
+ GH KKK
Sbjct: 1317 DDEDDGHLESTKKK 1330
Score = 38.5 bits (88), Expect = 0.020
Identities = 69/301 (22%), Positives = 108/301 (35%), Gaps = 58/301 (19%)
Query: 366 INKLESTARPSESS---EEFLEEEPEQRGIEFEDESSDRDAR---------------PAL 407
I + E T P E EE EEE Q E +E + DA P
Sbjct: 1204 IQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPET 1263
Query: 408 ET-QPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSED 466
ET +P+ E+++ + E E L+ EEED+ +E N D
Sbjct: 1264 ETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQ--------NDDHD 1315
Query: 467 STNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGS 526
+ + +ES+K E++ E E +E G E L +K+
Sbjct: 1316 ADDEDDGHLESTKKKELE-----------EQPTREDVKEEPGVQESFLD-ANMQKSREKI 1363
Query: 527 SDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTAL 586
D T + E SV VSE ++ + ED + + +
Sbjct: 1364 KDKEETELDSEEEQPSHDTSV--------VSEQMAGSEDDHEEDSHTKEELIELKEEEEI 1415
Query: 587 PQSSLIEVELEDVPFSQNAGQKNQSE--------EQSEASSEQLDQFTQSAEKAVDSSSE 638
P S E++LE V Q+ Q+ SE E++ A+ + L +TQ+ E S E
Sbjct: 1416 PHS---ELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVE 1472
Query: 639 E 639
+
Sbjct: 1473 D 1473
Score = 36.6 bits (83), Expect = 0.077
Identities = 72/341 (21%), Positives = 125/341 (36%), Gaps = 61/341 (17%)
Query: 334 KRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFL---EEEPEQR 390
K K +RF D + E Q K E+T SEE L EE+P Q
Sbjct: 871 KNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQ- 929
Query: 391 GIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSE 450
D +P L P++ +G +EP G+ + + ++
Sbjct: 930 -----------DGKPDL---PKRRLSEG-----VEPWRGQ----------LKKSPEALKC 960
Query: 451 VLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHM 510
L E + P SE ++ ESS E + ++PR +L +K +
Sbjct: 961 RLTEGSERLPRRYSEGDRAVLRGFSESS---EEEEEPESPRSSSPPILTKPTLKRKKPFL 1017
Query: 511 EEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLED 570
+ + RK+ H SS T+S V+ E E+ SE P + E
Sbjct: 1018 HRRRRV--RKRKHHNSSVVTETISE--------TTEVLDEPFEDSDSERPMPRLEPTFEI 1067
Query: 571 QGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQ------ 624
EE E ++ + P+ + +DV Q++ ++ +E+ + S+ D
Sbjct: 1068 DEEE---EEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKP 1124
Query: 625 FTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKK 665
+ ++ V +S E + P L++K KG ++K
Sbjct: 1125 VSLLRKRDVKNSPLEPDTSTP------LKKKKGWPKGKSRK 1159
Score = 30.8 bits (68), Expect = 4.2
Identities = 62/246 (25%), Positives = 98/246 (39%), Gaps = 39/246 (15%)
Query: 436 LKTSLITEEEDSTSE--------VLDEELKLQPFNS-SEDSTNLVPLVVESSKPPEVDAP 486
+ S+++EEE+ +E + EL++ S S ++ VES K PEV AP
Sbjct: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
Query: 487 DKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRK-KAHLGSSDNVATMSNEERSDGGFPN 545
+ R+ + D ++ + + RK + G D+ + EE S P
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLL--EETSSA--PQ 896
Query: 546 SVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIE-VELEDVPFSQN 604
E E+ SE T S E Q+ LP+ L E VE P+
Sbjct: 897 EQYGECGEK--SEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVE----PW--- 947
Query: 605 AGQKNQSEEQSEA----SSEQLDQFTQSAEKAV-----DSSSEEIEVE------VPVVDR 649
GQ +S E + SE+L + ++AV +SS EE E E P++ +
Sbjct: 948 RGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTK 1007
Query: 650 RNLRRK 655
L+RK
Sbjct: 1008 PTLKRK 1013
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 53.5 bits (127), Expect = 6e-07
Identities = 66/333 (19%), Positives = 141/333 (42%), Gaps = 19/333 (5%)
Query: 349 SSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALE 408
+ +GE+E + + + A+ S + +E+ E +EEE E+ + E S+ + + E
Sbjct: 1236 AEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE 1295
Query: 409 TQPQQEKQDGEKESELEPMNGEIMDDS-LKTSLITE-EEDSTSEVLDEELKLQPF---NS 463
+P++E+ + ++ + + + DD L+++ E EE T E + EE +Q +
Sbjct: 1296 PEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDAN 1355
Query: 464 SEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKL------SLL 517
+ S + E+ E + P + +M E +E H +E+L +
Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEI 1415
Query: 518 PRKKAHLGSSDNVATMSNEERS--DGGFPN---SVIAEFSEEPVSENLSPNTTSSLEDQG 572
P + L + V +++ EE S +G + + ++ A + + ++ S +ED
Sbjct: 1416 PHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCH 1475
Query: 573 EEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKA 632
+ P + + P S+ V +VP + +G S EQ S+ + S
Sbjct: 1476 ASEHNSPISSVQSHPSQSVRSVSSPNVP-ALESGYTQISPEQGSLSAPSMQNMETSPMMD 1534
Query: 633 VDSSSEEIE--VEVPVVDRRNLRRKAKGHKGPA 663
V S S+ + V+ D ++ + ++ P+
Sbjct: 1535 VPSVSDHSQQVVDSGFSDLGSIESTTENYENPS 1567
Score = 38.5 bits (88), Expect = 0.020
Identities = 66/314 (21%), Positives = 109/314 (34%), Gaps = 47/314 (14%)
Query: 381 EFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEP-------MNGEIM- 432
E + E E FED S+R T E+++ E E+EL P + +++
Sbjct: 1036 ETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFRRLSSQDVLR 1095
Query: 433 -DDSLKTSLITEEEDSTSEVLDEELKLQPF---------NSSEDSTNLVPLVVESSKPPE 482
S K EEED S+ D+ L+P NS + PL + P
Sbjct: 1096 CQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKG 1155
Query: 483 VD--------APDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPR--KKAHLGSSDNVAT 532
P + P S +M T + + E + +P+ +K + S+
Sbjct: 1156 KSRKPIHWKKRPGRKPGFKLSREIMPVST---QACVIEPIVSIPKAGRKPKIQESEETV- 1211
Query: 533 MSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLI 592
E + D P E E + + E + E+ S ++ S+
Sbjct: 1212 ---EPKEDMPLP-------EERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSP 1261
Query: 593 EVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNL 652
E E ++ + + SEEQ ++ EQ Q E+ E+ E D +
Sbjct: 1262 ETETKEPEVEEEEEKPRVSEEQRQSEEEQ-----QELEEPEPEEEEDAAAETAQNDDHDA 1316
Query: 653 RRKAKGHKGPAKKK 666
+ GH KKK
Sbjct: 1317 DDEDDGHLESTKKK 1330
Score = 38.5 bits (88), Expect = 0.020
Identities = 69/301 (22%), Positives = 108/301 (35%), Gaps = 58/301 (19%)
Query: 366 INKLESTARPSESS---EEFLEEEPEQRGIEFEDESSDRDAR---------------PAL 407
I + E T P E EE EEE Q E +E + DA P
Sbjct: 1204 IQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPET 1263
Query: 408 ET-QPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSED 466
ET +P+ E+++ + E E L+ EEED+ +E N D
Sbjct: 1264 ETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQ--------NDDHD 1315
Query: 467 STNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGS 526
+ + +ES+K E++ E E +E G E L +K+
Sbjct: 1316 ADDEDDGHLESTKKKELE-----------EQPTREDVKEEPGVQESFLD-ANMQKSREKI 1363
Query: 527 SDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTAL 586
D T + E SV VSE ++ + ED + + +
Sbjct: 1364 KDKEETELDSEEEQPSHDTSV--------VSEQMAGSEDDHEEDSHTKEELIELKEEEEI 1415
Query: 587 PQSSLIEVELEDVPFSQNAGQKNQSE--------EQSEASSEQLDQFTQSAEKAVDSSSE 638
P S E++LE V Q+ Q+ SE E++ A+ + L +TQ+ E S E
Sbjct: 1416 PHS---ELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVE 1472
Query: 639 E 639
+
Sbjct: 1473 D 1473
Score = 36.6 bits (83), Expect = 0.077
Identities = 72/341 (21%), Positives = 125/341 (36%), Gaps = 61/341 (17%)
Query: 334 KRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFL---EEEPEQR 390
K K +RF D + E Q K E+T SEE L EE+P Q
Sbjct: 871 KNRKTQERFGDKDSKLLLEETSSAPQEQYGECGEKSEATQEQYTESEEQLVASEEQPSQ- 929
Query: 391 GIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSE 450
D +P L P++ +G +EP G+ + + ++
Sbjct: 930 -----------DGKPDL---PKRRLSEG-----VEPWRGQ----------LKKSPEALKC 960
Query: 451 VLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHM 510
L E + P SE ++ ESS E + ++PR +L +K +
Sbjct: 961 RLTEGSERLPRRYSEGDRAVLRGFSESS---EEEEEPESPRSSSPPILTKPTLKRKKPFL 1017
Query: 511 EEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLED 570
+ + RK+ H SS T+S V+ E E+ SE P + E
Sbjct: 1018 HRRRRV--RKRKHHNSSVVTETISE--------TTEVLDEPFEDSDSERPMPRLEPTFEI 1067
Query: 571 QGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQ------ 624
EE E ++ + P+ + +DV Q++ ++ +E+ + S+ D
Sbjct: 1068 DEEE---EEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKP 1124
Query: 625 FTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKK 665
+ ++ V +S E + P L++K KG ++K
Sbjct: 1125 VSLLRKRDVKNSPLEPDTSTP------LKKKKGWPKGKSRK 1159
Score = 30.8 bits (68), Expect = 4.2
Identities = 62/246 (25%), Positives = 98/246 (39%), Gaps = 39/246 (15%)
Query: 436 LKTSLITEEEDSTSE--------VLDEELKLQPFNS-SEDSTNLVPLVVESSKPPEVDAP 486
+ S+++EEE+ +E + EL++ S S ++ VES K PEV AP
Sbjct: 781 VSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAP 840
Query: 487 DKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRK-KAHLGSSDNVATMSNEERSDGGFPN 545
+ R+ + D ++ + + RK + G D+ + EE S P
Sbjct: 841 VSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLL--EETSSA--PQ 896
Query: 546 SVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIE-VELEDVPFSQN 604
E E+ SE T S E Q+ LP+ L E VE P+
Sbjct: 897 EQYGECGEK--SEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVE----PW--- 947
Query: 605 AGQKNQSEEQSEA----SSEQLDQFTQSAEKAV-----DSSSEEIEVE------VPVVDR 649
GQ +S E + SE+L + ++AV +SS EE E E P++ +
Sbjct: 948 RGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTK 1007
Query: 650 RNLRRK 655
L+RK
Sbjct: 1008 PTLKRK 1013
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 52.4 bits (124), Expect = 1e-06
Identities = 79/325 (24%), Positives = 141/325 (43%), Gaps = 42/325 (12%)
Query: 340 KRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSES-----SEEFLEEEPEQRGIEF 394
K+ D G+ EK S L+ S+N+ ++++ S S P ++
Sbjct: 226 KKALDLHLDFIVGQTEKYSDL-LSQSLNQPLTSSKAGSSPCLGSSSAASSPPPPASRLDD 284
Query: 395 ED------ESSDRDARPALETQPQQEKQDGE---KESELEPMNGEIMDDSLKTSL---IT 442
ED E + D +E + QQE D E +E EL GE+ + L SL +
Sbjct: 285 EDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLL 344
Query: 443 EEEDSTSEVL---DEELKLQPFNSSEDSTNLVPLVVESSKPPE-VDAPDKTPRIPDSEML 498
E S S+ D + + P +E+ P V+E PP V +K P PD +
Sbjct: 345 EGPSSPSQTPSSHDSDTRDGPEEGAEEEP---PQVLEIKPPPSAVTQRNKQPWHPDEDD- 400
Query: 499 MDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSE 558
+E T++E+ +E+ ++ ++ G D+ +S R ++ +++
Sbjct: 401 -EEFTANEEEAEDEEDTIAAEEQLE-GEVDHAMELSELAREGELSMEELLQQYAGA---- 454
Query: 559 NLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEAS 618
+P + SS ED+ E+ V +S P+ VE E+ P ++ Q + E++SE
Sbjct: 455 -YAPGSGSS-EDEDEDEVDA--NSSDCEPEGP---VEAEEPPQEDSSSQSDSVEDRSE-- 505
Query: 619 SEQLDQFTQSAEKAVDSSSEEIEVE 643
++ D+ ++ E + S+SEE E E
Sbjct: 506 -DEEDEHSEEEETSGSSASEESESE 529
Score = 32.7 bits (73), Expect = 1.1
Identities = 33/168 (19%), Positives = 60/168 (35%), Gaps = 11/168 (6%)
Query: 288 EYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQD--- 344
E+ A E+ + E D++ E +S R G L ++ +++
Sbjct: 402 EFTANEEEAEDEE-----DTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYA 456
Query: 345 --SEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRD 402
S S + EDE + +S +E+ P E S + E R + EDE S+ +
Sbjct: 457 PGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSS-QSDSVEDRSEDEEDEHSEEE 515
Query: 403 ARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSE 450
+ E ++ E + E DD + ++ SE
Sbjct: 516 ETSGSSASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSE 563
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 52.0 bits (123), Expect = 2e-06
Identities = 75/333 (22%), Positives = 132/333 (39%), Gaps = 53/333 (15%)
Query: 290 EARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSS 349
+A ED S+E+Q + G D+ V + +G GK ++E
Sbjct: 73 KAPAEDGMSAELQ-----------GEANGLDEVKVESQREAG-------GKEDAEAELKK 114
Query: 350 SQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALET 409
GE E+T+ S + K E+ + P E+ EE E + ++ +++A+P
Sbjct: 115 EDGEKEETTVGSQEMTGRKEETKSEPKEA------EEKESTLASEKQKAEEKEAKP---- 164
Query: 410 QPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTN 469
+K D + EP + ++ KT+ ++EE +E +P + D
Sbjct: 165 -ESGQKADANDRDKPEP-KATVEEEDAKTA--SQEETGQR----KECSTEPKEKATDE-- 214
Query: 470 LVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDN 529
ES K D P+ PD + G +E EE ++A GS
Sbjct: 215 --EAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAED---AEEAEPGSPSE 269
Query: 530 VATMSNEERSDGG---FPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTAL 586
E+ +GG P+S E+ E P E + +T + G + V+ Q TS +
Sbjct: 270 EQEQDVEKEPEGGAGVIPSSP-EEWPESPTGEGHNLST----DGLGPDCVASGQ-TSPSA 323
Query: 587 PQSSLIEVELEDVPFSQNAGQKNQSEEQSEASS 619
+SS +V + P S ++G+K + + S+
Sbjct: 324 SESSPSDVP-QSPPESPSSGEKKEKAPERRVSA 355
Score = 29.6 bits (65), Expect = 9.4
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 20/160 (12%)
Query: 269 SQNEPKRPMSGEYGPAS----VPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSV 324
+++EPK E AS E EA+ E Q ++ D K +T E D +
Sbjct: 136 TKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADAN---DRDKPEPKATVEEEDAKTA 192
Query: 325 STHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLE 384
S + + G+R + S + DE+ S A + E+ A P E +
Sbjct: 193 S---------QEETGQRKECSTEPKEKATDEEAKAESQKAVVED-EAKAEPKEPDGKEEA 242
Query: 385 EEPEQRGIEFEDESSD-RDARPALETQPQQEKQDGEKESE 423
+ + + ++E+ D +A P + ++++QD EKE E
Sbjct: 243 KHGAKEEADAKEEAEDAEEAEPG--SPSEEQEQDVEKEPE 280
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 51.2 bits (121), Expect = 3e-06
Identities = 94/442 (21%), Positives = 172/442 (38%), Gaps = 59/442 (13%)
Query: 267 ALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKD-----------AFAST 315
AL+ E + + E G + R D + + + + D S+
Sbjct: 93 ALNSQEEEEVIVTEVGQRDSEDVSKRDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSS 152
Query: 316 SEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSL-TASINKLESTAR 374
++ + T +++ ++ K+ K F +F+ + + EK L T ++ E A
Sbjct: 153 ESNLEELTQPTESQANDIGFKKVFK-FVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAG 211
Query: 375 PSESSEEFL--------EEEPEQRGIEFED----ESSDRDARPALETQPQQE--KQDGEK 420
+ + L E EP+Q + E+ E S + P E+ E K++GE+
Sbjct: 212 AGDHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEE 271
Query: 421 ESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEE-----LKLQPFNSSEDSTNLVPLVV 475
+ E EP TS +T E ST + + K F ++ V
Sbjct: 272 KQEKEPSKSA----ESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDE------V 321
Query: 476 ESSKPPEVDAPDKTPRIPD--SEMLMDEGTSDEKGHMEEKLSLL--PR-----KKAHLGS 526
E+S+ + P+K D +E+ ++ T+ E+ H +E PR +K L S
Sbjct: 322 EASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPS 381
Query: 527 SDNVA-TMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTA 585
+ V+ + E V E E E ++ S++E++ EE +E +ET+ +
Sbjct: 382 EEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGS 441
Query: 586 LPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS--SEEIEVE 643
+P L+E++ E Q A + + E D TQ A+ + D S+ E
Sbjct: 442 VPAEELVEMDAE----PQEAEPAKELVKLKETCVSGEDP-TQGADLSPDEKVLSKPPEGV 496
Query: 644 VPVVDRRNLRRKAKGHKGPAKK 665
V V+ + + + K P KK
Sbjct: 497 VSEVEMLSSQERMKVQGSPLKK 518
Score = 49.3 bits (116), Expect = 1e-05
Identities = 57/310 (18%), Positives = 125/310 (40%), Gaps = 17/310 (5%)
Query: 343 QDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRD 402
++ +F++ GED + A + +A + LE E + ++++ + D
Sbjct: 1460 KNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGE-KTTSLKWKSDEVDEQ 1518
Query: 403 ARPALETQPQQEKQDGEKES---ELEPMNGEIMDDSLKTSL--ITEEEDSTSEVLDEELK 457
E + +D E E+ ELE + +++ + ++T++ E++ +E+L EL+
Sbjct: 1519 VA-CQEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQ 1577
Query: 458 LQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLL 517
Q DS + + + P+ A D+TP E + + +S
Sbjct: 1578 TQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEA 1637
Query: 518 PRKKAHL---GSSDN-----VATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLE 569
K + GS+ N + +EE G SV + ++E + + E
Sbjct: 1638 SEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKE 1697
Query: 570 DQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSA 629
D+ + V +P+ ++AL + ++ P G K + +E ++ Q + +
Sbjct: 1698 DEKGDDVDDPENQNSALADTDASGGLTKESP--DTNGPKQKEKEDAQEVELQEGKVHSES 1755
Query: 630 EKAVDSSSEE 639
+KA+ ++E
Sbjct: 1756 DKAITPQAQE 1765
Score = 33.5 bits (75), Expect = 0.65
Identities = 56/293 (19%), Positives = 102/293 (34%), Gaps = 24/293 (8%)
Query: 286 VPEYEARTEDNQSSEM--QLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQ 343
V EA+TE ++ Q T +S + A +E + + + T ++ L K +
Sbjct: 1096 VDAQEAKTEPFTQGKVVGQTTPESFEKA-PQVTESIESSELVTTCQAETLAGVKSQEMVM 1154
Query: 344 DSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE------QRGIEFEDE 397
+ E S+T + + ++ + + EE E G E E
Sbjct: 1155 EQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAV 1214
Query: 398 SSDRDARPALETQPQQE--KQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEE 455
+ ++ PA + QE K+ + E LE + E+ +++ TE + DE+
Sbjct: 1215 PAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEK 1274
Query: 456 LKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLS 515
K PF + + + V K EV L EGT + + ++ L
Sbjct: 1275 TKDVPFFEGLEGSIDTGITVSREKVTEV-------------ALKGEGTEEAECKKDDALE 1321
Query: 516 LLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSL 568
L K+ + + E P V E E + +S + L
Sbjct: 1322 LQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQL 1374
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 50.4 bits (119), Expect = 5e-06
Identities = 60/242 (24%), Positives = 96/242 (39%), Gaps = 39/242 (16%)
Query: 365 SINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESEL 424
+IN + E EE EEE E+ +FE+E D + E ++E+++ E E E
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEE-DFEEEEEDEE-----EYFEEEEEEEEEFEEEF 935
Query: 425 EPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSS----EDSTNLVPLVVESSKP 480
E GE+ ++ EEED E EE++ F ++ E+ P + + P
Sbjct: 936 EEEEGELEEEE-------EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPP 988
Query: 481 PEVDAPDKTPRIPDSE-----MLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSN 535
PE +P K P+ E + + GT +E+G + +L P G +
Sbjct: 989 PE--SPPKVQPEPEPEPGLLLEVEEPGTEEERG-ADTAPTLAPEALPSQGEVER----EG 1041
Query: 536 EERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVE 595
E + G P ++ E P P + G + V P ET P +E E
Sbjct: 1042 ESPAAGPPPQELVEEEPSAP------PTLLEEETEDGSDKVQPPPET----PAEEEMETE 1091
Query: 596 LE 597
E
Sbjct: 1092 TE 1093
Score = 35.4 bits (80), Expect = 0.17
Identities = 54/256 (21%), Positives = 90/256 (35%), Gaps = 27/256 (10%)
Query: 343 QDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRD 402
++ E + E+E+ + E E EE EEE E+ E E+E + D
Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEED 950
Query: 403 ARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFN 462
E + ++ + G E+E G +L +L E K+QP
Sbjct: 951 EEEEEELEEVEDLEFGTAGGEVE--EGAPPPPTLPPALPPPESPP---------KVQPEP 999
Query: 463 SSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKA 522
E + L VE E D P + E L +G + +G E + P ++
Sbjct: 1000 EPEPG---LLLEVEEPGTEEERGADTAPTLA-PEALPSQGEVEREG--ESPAAGPPPQEL 1053
Query: 523 HLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQET 582
T+ EE DG + + E P E + T + E + E ++
Sbjct: 1054 VEEEPSAPPTLLEEETEDG---SDKVQPPPETPAEEEMETETEA-------EALQEKEQD 1103
Query: 583 STALPQSSLIEVELED 598
TA + I+ +D
Sbjct: 1104 DTAAMLADFIDCPPDD 1119
Score = 30.0 bits (66), Expect = 7.2
Identities = 19/88 (21%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 556 VSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVP--FSQNAGQKNQSEE 613
+ E+L+ +S +++ EE E +E + E E ED F + ++ + EE
Sbjct: 874 LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933
Query: 614 QSEASSEQLDQFTQSAEKAVDSSSEEIE 641
+ E +L++ + ++ + EE+E
Sbjct: 934 EFEEEEGELEEEEEEEDEEEEEELEEVE 961
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 50.1 bits (118), Expect = 7e-06
Identities = 94/429 (21%), Positives = 172/429 (40%), Gaps = 54/429 (12%)
Query: 269 SQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHT 328
S++ KR E S ++ T+D Q ++ + S+ ++ + T +
Sbjct: 14 SEDVSKRDSDKEMATKSAVVHDI-TDDGQEETPEII-----EQIPSSESNLEELTQPTES 67
Query: 329 RSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSL-TASINKLESTARPSESSEEFL---- 383
++ ++ K+ K F +F+ + + EK L T ++ E A + + L
Sbjct: 68 QANDIGFKKVFK-FVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGE 126
Query: 384 ----EEEPEQRGIEFED----ESSDRDARPALETQPQQE--KQDGEKESELEPMNGEIMD 433
E EP+Q + E+ E S + P E+ E K++GE++ E EP
Sbjct: 127 AASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSA--- 183
Query: 434 DSLKTSLITEEEDSTSEVLDEE-----LKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDK 488
TS +T E ST + + K F ++ VE+S+ + P+K
Sbjct: 184 -ESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDE------VEASEKKKEQEPEK 236
Query: 489 TPRIPD--SEMLMDEGTSDEKGHMEEKLSLL--PR-----KKAHLGSSDNVA-TMSNEER 538
D +E+ ++ T+ E+ H +E PR +K L S + V+ + E
Sbjct: 237 VDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEE 296
Query: 539 SDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELED 598
V E E E ++ S++E++ EE +E +ET+ ++P L+E++ E
Sbjct: 297 KPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMDAE- 355
Query: 599 VPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSS--SEEIEVEVPVVDRRNLRRKA 656
Q A + + E D TQ A+ + D S+ E V V+ + + +
Sbjct: 356 ---PQEAEPAKELVKLKETCVSGEDP-TQGADLSPDEKVLSKPPEGVVSEVEMLSSQERM 411
Query: 657 KGHKGPAKK 665
K P KK
Sbjct: 412 KVQGSPLKK 420
Score = 49.3 bits (116), Expect = 1e-05
Identities = 57/310 (18%), Positives = 125/310 (40%), Gaps = 17/310 (5%)
Query: 343 QDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRD 402
++ +F++ GED + A + +A + LE E + ++++ + D
Sbjct: 1362 KNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGE-KTTSLKWKSDEVDEQ 1420
Query: 403 ARPALETQPQQEKQDGEKES---ELEPMNGEIMDDSLKTSL--ITEEEDSTSEVLDEELK 457
E + +D E E+ ELE + +++ + ++T++ E++ +E+L EL+
Sbjct: 1421 VA-CQEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQ 1479
Query: 458 LQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLL 517
Q DS + + + P+ A D+TP E + + +S
Sbjct: 1480 TQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEA 1539
Query: 518 PRKKAHL---GSSDN-----VATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLE 569
K + GS+ N + +EE G SV + ++E + + E
Sbjct: 1540 SEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKE 1599
Query: 570 DQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSA 629
D+ + V +P+ ++AL + ++ P G K + +E ++ Q + +
Sbjct: 1600 DEKGDDVDDPENQNSALADTDASGGLTKESP--DTNGPKQKEKEDAQEVELQEGKVHSES 1657
Query: 630 EKAVDSSSEE 639
+KA+ ++E
Sbjct: 1658 DKAITPQAQE 1667
Score = 33.5 bits (75), Expect = 0.65
Identities = 56/293 (19%), Positives = 102/293 (34%), Gaps = 24/293 (8%)
Query: 286 VPEYEARTEDNQSSEM--QLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQ 343
V EA+TE ++ Q T +S + A +E + + + T ++ L K +
Sbjct: 998 VDAQEAKTEPFTQGKVVGQTTPESFEKA-PQVTESIESSELVTTCQAETLAGVKSQEMVM 1056
Query: 344 DSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE------QRGIEFEDE 397
+ E S+T + + ++ + + EE E G E E
Sbjct: 1057 EQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAV 1116
Query: 398 SSDRDARPALETQPQQE--KQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEE 455
+ ++ PA + QE K+ + E LE + E+ +++ TE + DE+
Sbjct: 1117 PAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEK 1176
Query: 456 LKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLS 515
K PF + + + V K EV L EGT + + ++ L
Sbjct: 1177 TKDVPFFEGLEGSIDTGITVSREKVTEV-------------ALKGEGTEEAECKKDDALE 1223
Query: 516 LLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSL 568
L K+ + + E P V E E + +S + L
Sbjct: 1224 LQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQL 1276
>gi|157694505 LINE-1 type transposase domain containing 1 [Homo
sapiens]
Length = 865
Score = 50.1 bits (118), Expect = 7e-06
Identities = 86/363 (23%), Positives = 134/363 (36%), Gaps = 63/363 (17%)
Query: 317 EGHDKTSVSTHTRSGN----------LKRPKIGK-------RFQDSEFSSSQGEDEKTSQ 359
E DKT + + R+G LK K+ K Q+ EFS + DE+ S
Sbjct: 334 EKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASG 393
Query: 360 TSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGE 419
+ LE EE EEE E G+E EDE+S + ++E+Q E
Sbjct: 394 MEDDEDTSGLEEEEEEPSGLEE--EEEEEASGLE-EDEASGLE---------EEEEQTSE 441
Query: 420 KESELE-------PMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVP 472
++S + EI D ++T+ I EDS SE +E SSE
Sbjct: 442 QDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEG------KSSETGK---- 491
Query: 473 LVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGH------MEEKLSLLPRKKAH--- 523
V+++ E A + IP S ++ D G H EE+ + +P +
Sbjct: 492 --VKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTP 549
Query: 524 -----LGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSE 578
L S MS++E N I+ + + T E+ +
Sbjct: 550 CLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADL 609
Query: 579 PQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSE 638
+ET L +SS+I E N + + E S + L E+ +DS +
Sbjct: 610 TEETEENL-RSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLED 668
Query: 639 EIE 641
+IE
Sbjct: 669 QIE 671
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 50.1 bits (118), Expect = 7e-06
Identities = 80/373 (21%), Positives = 142/373 (38%), Gaps = 39/373 (10%)
Query: 310 DAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGED-------EKTSQTSL 362
DA A EG S T +G+ ++G+ Q+ E S +GE E Q
Sbjct: 1766 DAMAQEREGKTHNS---ETSAGS----ELGEAEQEGEGISERGETGGQGSGHEDNLQGEA 1818
Query: 363 TASINK---LESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDG- 418
A ++ A E+ E E +PE G+E + D E QP+ E +
Sbjct: 1819 AAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEG-EAQPESEDVEAP 1877
Query: 419 EKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSS--------EDSTNL 470
E E E +P + ++ ++ + + E +E + E + QP S ED
Sbjct: 1878 EAEGEAQPESEDV--ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPES 1935
Query: 471 VPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNV 530
+ ++ +A +T P+SE++ + +E E + L + +
Sbjct: 1936 EGAEAQEAEEAAQEAEGQTQ--PESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEA 1993
Query: 531 ATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGE-EGVSEPQETSTALPQS 589
S + + AE +P S+ + S E+ E EG ++ E A P+S
Sbjct: 1994 QPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTE-GDAQPES 2052
Query: 590 SLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDR 649
+E + + G+ ++E ++ SE +D Q AE SE +E +
Sbjct: 2053 DGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD--AQEAEGEAQPESEGVEAP----EA 2106
Query: 650 RNLRRKAKGHKGP 662
+KA+G + P
Sbjct: 2107 EGEAQKAEGIEAP 2119
Score = 49.7 bits (117), Expect = 9e-06
Identities = 71/357 (19%), Positives = 123/357 (34%), Gaps = 20/357 (5%)
Query: 287 PEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSE 346
PE E E Q +S+ +A + E ++ + + + G+ +SE
Sbjct: 1901 PESEGAEAPEAEKEAQPETESV-EALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESE 1959
Query: 347 FSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPA 406
SQ +E+ S ++E + +E + E+ E E E + ++ +A+P
Sbjct: 1960 VIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPE 2019
Query: 407 LETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPF--NSS 464
+ Q K +GE+ E+E + D+ S E ++ E + E ++Q +
Sbjct: 2020 SDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAH 2079
Query: 465 EDSTNLVPLVVESSKPPE---VDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKK 521
+S ++ E PE V+AP+ +E + T E E + +
Sbjct: 2080 PESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEG 2139
Query: 522 AHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQE 581
S+ V AE +P SE + EGV P+
Sbjct: 2140 EAQPESEGVEAQD--------------AEGEAQPESEGIEAQEAEEEAQPELEGVEAPEA 2185
Query: 582 TSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSE 638
A P+S IE + E + EA E T AE SE
Sbjct: 2186 EGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESE 2242
Score = 36.2 bits (82), Expect = 0.10
Identities = 60/310 (19%), Positives = 118/310 (38%), Gaps = 49/310 (15%)
Query: 337 KIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFED 396
K + DS S G+ E Q +N +E E + EQR +
Sbjct: 1233 KTSNQRPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAE--RDSEEQRASSNLE 1290
Query: 397 ESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEE- 455
+ ++ + ++ + +E +GE L+ + EE T E L EE
Sbjct: 1291 QLAENTVQEEVQLEETKEGTEGE---------------GLQEEAVQLEETKTEEGLQEEG 1335
Query: 456 LKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEK------GH 509
++L+ +E + + +++ ++T E L +EG E+ G
Sbjct: 1336 VQLEETKETEGEG-------QQEEEAQLEEIEET----GGEGLQEEGVQLEEVKEGPEGG 1384
Query: 510 MEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLE 569
++ + K+ L +V +E S+ P+ ++ ++PV E + ++S E
Sbjct: 1385 LQGEALEEGLKEEGLPEEGSV---HGQELSEASSPDGKGSQ-EDDPVQEEEAGRASASAE 1440
Query: 570 DQGEEGVSEPQETSTALPQS----------SLIEVELEDVPFSQNAGQKNQSEEQSEASS 619
EG EP E + L ++ S +E LE P + GQ++ + ++ ++
Sbjct: 1441 PCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAA 1500
Query: 620 EQLDQFTQSA 629
E+ SA
Sbjct: 1501 ERSSSVACSA 1510
Score = 29.6 bits (65), Expect = 9.4
Identities = 21/98 (21%), Positives = 44/98 (44%), Gaps = 12/98 (12%)
Query: 569 EDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQS 628
+ G EG+ P+ A P+S +E P ++ Q+ + E Q E+ ++
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVE-----APEAEGDAQEAEGEAQPESED------VEA 1876
Query: 629 AEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKK 666
E ++ E +VE P + ++ +++G + P +K
Sbjct: 1877 PEAEGEAQPESEDVETPEAE-WEVQPESEGAEAPEAEK 1913
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 49.7 bits (117), Expect = 9e-06
Identities = 74/359 (20%), Positives = 146/359 (40%), Gaps = 27/359 (7%)
Query: 292 RTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQ 351
R + ++ + ++T+D+ ++ E + + + G+ K+ K+ + E +
Sbjct: 274 RKFEEETVKSKVTVDT--GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKE----E 327
Query: 352 GEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQP 411
E EK S A++ ++ + EE + E E+R E+ + R LE +
Sbjct: 328 KEKEKKKGPS-KATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEK 386
Query: 412 QQEKQDGEKE-SELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNL 470
++ K+ EKE E G+++ S + + E +T ++L + P S+DS
Sbjct: 387 RERKKQKEKERKERLKKEGKLLTKSQREARARAE--ATLKLLQAQGVEVP---SKDSLPK 441
Query: 471 VPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLP-----RKKAHLG 525
+ E K ++ ++ + +S L E+G E++ + P +
Sbjct: 442 KRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDA 501
Query: 526 SSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTA 585
D+ M+++E ++ N V E E P E E++ E+ SE +E
Sbjct: 502 GLDDWEAMASDEETEKVEGNKVHIEVKENPEEEE------EEEEEEEEDEESEEEEEEEG 555
Query: 586 LPQSSLIEVELEDVPFSQNAGQ---KNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIE 641
+ S + E E V +++G+ K S+E S S D E+A D + IE
Sbjct: 556 ESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIE 614
Score = 42.7 bits (99), Expect = 0.001
Identities = 75/414 (18%), Positives = 163/414 (39%), Gaps = 69/414 (16%)
Query: 269 SQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHT 328
S+++ K+ G+ S + ++ +++ S+ + T + ++ + + D +
Sbjct: 93 SKDKKKKGQKGK--KQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKA 150
Query: 329 RSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE 388
+ K K K++ SE EDE S+ S ++ S+ + S+EFL+
Sbjct: 151 KG---KAQKSNKKWDGSE------EDEDNSKKIKERS--RINSSGESGDESDEFLQSRKG 199
Query: 389 QR-------GIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLI 441
Q+ G E + D DA ++T Q++ + E+E + ++ K +
Sbjct: 200 QKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD------EEKAKLRKL 253
Query: 442 TEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDE 501
E+E+ + D+ + + E+ T + V++ P + +TP + + D+
Sbjct: 254 KEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDK 313
Query: 502 GTSD---EKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSE 558
D +KG EEK +E+ G P+ + +E +++
Sbjct: 314 KKKDKKKKKGEKEEK---------------------EKEKKKG--PSKATVKAMQEALAK 350
Query: 559 NLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEAS 618
L+++ E E +E L + E E + + +K + +E+ E
Sbjct: 351 ---------LKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERL 401
Query: 619 SEQLDQFTQSAEKAVDSSSEEIE------VEVPVVDRRNLRRKAKGHKGPAKKK 666
++ T+S +A + ++ VEVP D +L +K ++ +KK
Sbjct: 402 KKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKD--SLPKKRPIYEDKKRKK 453
Score = 38.1 bits (87), Expect = 0.027
Identities = 67/362 (18%), Positives = 127/362 (35%), Gaps = 59/362 (16%)
Query: 287 PEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPK---IGKRFQ 343
P E+ ED+ +S T+ K A E K + LK + GK+ Q
Sbjct: 210 PNIESGNEDDDASFKIKTVAQKK---AEKKERERKKRDEEKAKLRKLKEKEELETGKKDQ 266
Query: 344 DSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDA 403
+ S + +E+T ++ +T + ++ EE+ E +D D+
Sbjct: 267 SKQKESQRKFEEETVKSKVTVDTGVIPAS-----------EEKAETPTAAEDDNEGDKKK 315
Query: 404 RPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNS 463
+ + + + EK++ EKE + P + + + EEE+ +E +K
Sbjct: 316 KD--KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIK------ 367
Query: 464 SEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAH 523
R+ + E E E+ E K +K
Sbjct: 368 ---------------------------RLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Query: 524 LGSSDNVATMSNEE-RSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVS---EP 579
L + T S E R+ ++ E S++ P ED+ + + E
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460
Query: 580 QETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEE 639
+E S ++ + +EV + VP + + EE+ + LD + A D +E+
Sbjct: 461 KEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMAS---DEETEK 517
Query: 640 IE 641
+E
Sbjct: 518 VE 519
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 48.1 bits (113), Expect = 3e-05
Identities = 76/326 (23%), Positives = 130/326 (39%), Gaps = 65/326 (19%)
Query: 349 SSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALE 408
SS T + +S + ++ S+SS + EEE QR E +++ + A
Sbjct: 469 SSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAAL 528
Query: 409 TQPQQ------EKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFN 462
+QPQQ EK EK+ E E+ EE+ S+ + K N
Sbjct: 529 SQPQQNKPKKKEKDKKEKKKEKHKRKEEV------------EENKKSKAKEPPPKKTKKN 576
Query: 463 SSEDS--TNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRK 520
+S +S + P ++S PP ++ ++ P S +EK + ++ LP +
Sbjct: 577 NSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMS--------YEEKRQLSLDINKLPGE 628
Query: 521 KAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQ 580
K LG ++ S E P+ + +F E L P+T LE + + +
Sbjct: 629 K--LGRVVHI-IQSREPSLKNSNPDEIEIDF------ETLKPSTLRELERYVTSCLRKKR 679
Query: 581 ETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEI 640
+ PQ+ ++V + ++ K S +SE+SSE + S SE+
Sbjct: 680 K-----PQAEKVDV------IAGSSKMKGFSSSESESSSE-----------SSSSDSEDS 717
Query: 641 EVEVPVVDRRNLRRKAKGHKGPAKKK 666
E E+ + K KGH G +KK
Sbjct: 718 ETEMAP------KSKKKGHPGREQKK 737
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 48.1 bits (113), Expect = 3e-05
Identities = 55/274 (20%), Positives = 112/274 (40%), Gaps = 25/274 (9%)
Query: 380 EEFLEEEPEQRGIEFEDESS-DRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKT 438
++ L E PEQ + ES D++ + + + + + K + + +++ L +
Sbjct: 17 DDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSS 76
Query: 439 S------LITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKT-PR 491
S +++ + S +E +EE + N D+ + L +S+ P + P+KT R
Sbjct: 77 SVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVR 136
Query: 492 IPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEF 551
D E T D E++ L ++A S + +++EE S
Sbjct: 137 KRDPERRAKSPTPDG----SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGS----- 187
Query: 552 SEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQS 611
S + N T + E+ EE V E +E + ++ + E+ + ++ +
Sbjct: 188 ---SGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244
Query: 612 EEQSEASSEQLDQFTQ-----SAEKAVDSSSEEI 640
EE+ E ++ DQ + + +A DS SE +
Sbjct: 245 EEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/211 (24%), Positives = 85/211 (40%), Gaps = 30/211 (14%)
Query: 264 KILALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHD--- 320
K L+ S + KR +S + A+ E + E+ Q SE +D+ + S+S +
Sbjct: 72 KPLSSSVSNNKRIVSTKGKSAT----EYKNEEYQRSERNKRLDADRKIRLSSSASREPYK 127
Query: 321 ----KTSVSTHTRSGNLKRP----------KIGKRFQDSEFSSSQ-------GEDEKTSQ 359
KT V K P ++ +R S SS + G D +T
Sbjct: 128 NQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGS 187
Query: 360 TSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGE 419
+ +S + +T E EE +EE+ E EDE D D E + ++E+++ E
Sbjct: 188 SG--SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE 245
Query: 420 KESELEPMNGEIMDDSLKTSLITEEEDSTSE 450
+E E E + ++ +E DS SE
Sbjct: 246 EEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276
Score = 31.2 bits (69), Expect = 3.2
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 5/100 (5%)
Query: 369 LESTARPSESSEEFLEE-EPEQRGIEFEDESSDRDARPALETQPQQE--KQDGEKESELE 425
LE R S SS+ EE E+ G + E SS T+ ++E ++D E++ E+E
Sbjct: 157 LEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVE 216
Query: 426 PMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSE 465
E D+ + EEE+ E +EE + + + E
Sbjct: 217 EDAEE--DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
Score = 30.0 bits (66), Expect = 7.2
Identities = 47/213 (22%), Positives = 78/213 (36%), Gaps = 32/213 (15%)
Query: 249 YQRIPVTRALQREALKILALSQNEPKRPMSGEYGPASV----PEYEARTEDNQSSEMQLT 304
YQR + L +A + + LS + + P + V PE A++ SE
Sbjct: 100 YQRSERNKRL--DADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSER--- 154
Query: 305 IDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTA 364
I D AS S K V++ + + G S QG + + + +
Sbjct: 155 IGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGS-------SDEQGNNTENEEEGVEE 207
Query: 365 SINKLESTARPSESSEEF--------LEEEPEQRGIEFEDESSDRDARPALETQPQQEKQ 416
+ + E +E EE EEE E+ E E+E ++D E ++E
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD-----ERDQKEEGN 262
Query: 417 DGEKESELEPMNGE---IMDDSLKTSLITEEED 446
D + SE E D S+++ T+ D
Sbjct: 263 DYDTRSEASDSGSESVSFTDGSVRSGSGTDGSD 295
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 48.1 bits (113), Expect = 3e-05
Identities = 55/274 (20%), Positives = 112/274 (40%), Gaps = 25/274 (9%)
Query: 380 EEFLEEEPEQRGIEFEDESS-DRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKT 438
++ L E PEQ + ES D++ + + + + + K + + +++ L +
Sbjct: 17 DDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSS 76
Query: 439 S------LITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKT-PR 491
S +++ + S +E +EE + N D+ + L +S+ P + P+KT R
Sbjct: 77 SVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVR 136
Query: 492 IPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEF 551
D E T D E++ L ++A S + +++EE S
Sbjct: 137 KRDPERRAKSPTPDG----SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGS----- 187
Query: 552 SEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQS 611
S + N T + E+ EE V E +E + ++ + E+ + ++ +
Sbjct: 188 ---SGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244
Query: 612 EEQSEASSEQLDQFTQ-----SAEKAVDSSSEEI 640
EE+ E ++ DQ + + +A DS SE +
Sbjct: 245 EEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/211 (24%), Positives = 85/211 (40%), Gaps = 30/211 (14%)
Query: 264 KILALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHD--- 320
K L+ S + KR +S + A+ E + E+ Q SE +D+ + S+S +
Sbjct: 72 KPLSSSVSNNKRIVSTKGKSAT----EYKNEEYQRSERNKRLDADRKIRLSSSASREPYK 127
Query: 321 ----KTSVSTHTRSGNLKRP----------KIGKRFQDSEFSSSQ-------GEDEKTSQ 359
KT V K P ++ +R S SS + G D +T
Sbjct: 128 NQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGS 187
Query: 360 TSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGE 419
+ +S + +T E EE +EE+ E EDE D D E + ++E+++ E
Sbjct: 188 SG--SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE 245
Query: 420 KESELEPMNGEIMDDSLKTSLITEEEDSTSE 450
+E E E + ++ +E DS SE
Sbjct: 246 EEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276
Score = 31.2 bits (69), Expect = 3.2
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 5/100 (5%)
Query: 369 LESTARPSESSEEFLEE-EPEQRGIEFEDESSDRDARPALETQPQQE--KQDGEKESELE 425
LE R S SS+ EE E+ G + E SS T+ ++E ++D E++ E+E
Sbjct: 157 LEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVE 216
Query: 426 PMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSE 465
E D+ + EEE+ E +EE + + + E
Sbjct: 217 EDAEE--DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
Score = 30.0 bits (66), Expect = 7.2
Identities = 47/213 (22%), Positives = 78/213 (36%), Gaps = 32/213 (15%)
Query: 249 YQRIPVTRALQREALKILALSQNEPKRPMSGEYGPASV----PEYEARTEDNQSSEMQLT 304
YQR + L +A + + LS + + P + V PE A++ SE
Sbjct: 100 YQRSERNKRL--DADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSER--- 154
Query: 305 IDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTA 364
I D AS S K V++ + + G S QG + + + +
Sbjct: 155 IGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGS-------SDEQGNNTENEEEGVEE 207
Query: 365 SINKLESTARPSESSEEF--------LEEEPEQRGIEFEDESSDRDARPALETQPQQEKQ 416
+ + E +E EE EEE E+ E E+E ++D E ++E
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD-----ERDQKEEGN 262
Query: 417 DGEKESELEPMNGE---IMDDSLKTSLITEEED 446
D + SE E D S+++ T+ D
Sbjct: 263 DYDTRSEASDSGSESVSFTDGSVRSGSGTDGSD 295
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 47.8 bits (112), Expect = 3e-05
Identities = 84/396 (21%), Positives = 150/396 (37%), Gaps = 53/396 (13%)
Query: 269 SQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHT 328
S+ K SG +S + E +EDN+ + + + S K A + + ST
Sbjct: 1104 SKRNTKEIQSG----SSSSDAEESSEDNKKKKQRTS--SKKKAVIVKEKKRNSLRTSTKR 1157
Query: 329 RSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE 388
+ ++ D + S +G ++ +T ++ T S +E L +
Sbjct: 1158 KQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVP 1217
Query: 389 QRGIEFEDESSDRDARPA----LETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEE 444
++ +D+ +D + R A LE D + S+ EP G+ +T EE
Sbjct: 1218 VT-VDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGK-----KRTGKQNEE 1271
Query: 445 EDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTS 504
DEE K Q NS DS + E SK P R+ ++ + +G S
Sbjct: 1272 NPG-----DEEAKNQ-VNSESDSDS------EESKKPRY-----RHRLLRHKLTVSDGES 1314
Query: 505 DEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNT 564
E E+K K+ N +S+E+ D F S ++E E E P T
Sbjct: 1315 GE----EKKTKPKEHKEV---KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ-RPRT 1366
Query: 565 TSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQ 624
S+ + + EE ++ + +++++ S+N + EE+ E E+ ++
Sbjct: 1367 RSAKKAELEENQRSYKQ------KKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1420
Query: 625 FTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHK 660
+ E D S P R+ +R+ K K
Sbjct: 1421 EEEEEEDENDDSKS------PGKGRKKIRKILKDDK 1450
Score = 40.8 bits (94), Expect = 0.004
Identities = 52/237 (21%), Positives = 97/237 (40%), Gaps = 40/237 (16%)
Query: 408 ETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDS 467
+TQ + D E E E++ M+ + K + ++ +SE +E + ++
Sbjct: 771 QTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSE---DEKHSKKGMDNQGH 827
Query: 468 TNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMD-EGTSDEKGHMEEKLSLLPRKKAHLGS 526
NL K + + D R + E EGT D+ + E LP+K+ S
Sbjct: 828 KNL--------KTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAS 879
Query: 527 SDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTAL 586
+D V +S +E+S +AE E+ S++L T ++D G+S+
Sbjct: 880 TDGVDKLSGKEQSFTSLEVRKVAETKEK--SKHLKTKTCKKVQD----GLSD-------- 925
Query: 587 PQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVE 643
++ +K+QS+E SE +Q + T+ +K D + I++E
Sbjct: 926 --------------IAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKME 968
Score = 40.8 bits (94), Expect = 0.004
Identities = 47/221 (21%), Positives = 89/221 (40%), Gaps = 35/221 (15%)
Query: 269 SQNEPK--RPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVST 326
S +EP+ + +G+ + + EA+ + N S+ + +S K + H T
Sbjct: 1254 SDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSD-SEESKKPRYRHRLLRHKLTVSDG 1312
Query: 327 HTRSGNLKRPKIGKRFQDS---EFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFL 383
+ +PK K + + SS ED ++ ++ +++ E RP S +
Sbjct: 1313 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1372
Query: 384 EEEPEQRGIEF----------EDESSDRDARPALETQPQQEKQDGEKESELE-------- 425
E E QR + ED SS+ + E + ++E+++ E+E E E
Sbjct: 1373 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1432
Query: 426 --PMNGE------IMDDSLKT---SLITEEEDSTSEVLDEE 455
P G + DD L+T + + EEE+ + + E
Sbjct: 1433 KSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERE 1473
Score = 34.7 bits (78), Expect = 0.29
Identities = 77/389 (19%), Positives = 150/389 (38%), Gaps = 56/389 (14%)
Query: 333 LKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE---- 388
LK+ + + +D + S +G +EK + + K+E S E L E E
Sbjct: 931 LKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHF 990
Query: 389 QRGI--------EFEDESS---DRDARPALETQPQQEKQDGEKES-----ELEPMNGEIM 432
+GI + E +S D+ ++ E EK G+ +S + + NG
Sbjct: 991 PKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYG 1050
Query: 433 DDSLKTSLI-----TEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVE---SSKPPEVD 484
+ + L+ ++ S+S+ +K NSS+ + L SSK +
Sbjct: 1051 REKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKE 1110
Query: 485 APDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAH---LGSSDNVATMSNEERSD- 540
+ E D ++ ++K ++ KK + + A +++ SD
Sbjct: 1111 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1170
Query: 541 -GGFPNSVIAEFSEE----PVSENLSPNT-TSSLEDQGEEGVS-----------EPQETS 583
NS+ S+E PV+ENL ++ T + G+E +S + +
Sbjct: 1171 EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPE 1230
Query: 584 TALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQ--FTQSAEKAV--DSSSEE 639
+ + L+E ++ ++ ++ EE + + +Q ++ + A+ V +S S+
Sbjct: 1231 NRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDS 1290
Query: 640 IEVEVPVVDRRNLRRK---AKGHKGPAKK 665
E + P R LR K + G G KK
Sbjct: 1291 EESKKPRYRHRLLRHKLTVSDGESGEEKK 1319
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 47.8 bits (112), Expect = 3e-05
Identities = 84/396 (21%), Positives = 150/396 (37%), Gaps = 53/396 (13%)
Query: 269 SQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHT 328
S+ K SG +S + E +EDN+ + + + S K A + + ST
Sbjct: 1142 SKRNTKEIQSG----SSSSDAEESSEDNKKKKQRTS--SKKKAVIVKEKKRNSLRTSTKR 1195
Query: 329 RSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE 388
+ ++ D + S +G ++ +T ++ T S +E L +
Sbjct: 1196 KQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVP 1255
Query: 389 QRGIEFEDESSDRDARPA----LETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEE 444
++ +D+ +D + R A LE D + S+ EP G+ +T EE
Sbjct: 1256 VT-VDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGK-----KRTGKQNEE 1309
Query: 445 EDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTS 504
DEE K Q NS DS + E SK P R+ ++ + +G S
Sbjct: 1310 NPG-----DEEAKNQ-VNSESDSDS------EESKKPRY-----RHRLLRHKLTVSDGES 1352
Query: 505 DEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNT 564
E E+K K+ N +S+E+ D F S ++E E E P T
Sbjct: 1353 GE----EKKTKPKEHKEV---KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ-RPRT 1404
Query: 565 TSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQ 624
S+ + + EE ++ + +++++ S+N + EE+ E E+ ++
Sbjct: 1405 RSAKKAELEENQRSYKQ------KKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1458
Query: 625 FTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHK 660
+ E D S P R+ +R+ K K
Sbjct: 1459 EEEEEEDENDDSKS------PGKGRKKIRKILKDDK 1488
Score = 40.8 bits (94), Expect = 0.004
Identities = 52/237 (21%), Positives = 97/237 (40%), Gaps = 40/237 (16%)
Query: 408 ETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDS 467
+TQ + D E E E++ M+ + K + ++ +SE +E + ++
Sbjct: 809 QTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSE---DEKHSKKGMDNQGH 865
Query: 468 TNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMD-EGTSDEKGHMEEKLSLLPRKKAHLGS 526
NL K + + D R + E EGT D+ + E LP+K+ S
Sbjct: 866 KNL--------KTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAS 917
Query: 527 SDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTAL 586
+D V +S +E+S +AE E+ S++L T ++D G+S+
Sbjct: 918 TDGVDKLSGKEQSFTSLEVRKVAETKEK--SKHLKTKTCKKVQD----GLSD-------- 963
Query: 587 PQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVE 643
++ +K+QS+E SE +Q + T+ +K D + I++E
Sbjct: 964 --------------IAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKME 1006
Score = 40.8 bits (94), Expect = 0.004
Identities = 47/221 (21%), Positives = 89/221 (40%), Gaps = 35/221 (15%)
Query: 269 SQNEPK--RPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVST 326
S +EP+ + +G+ + + EA+ + N S+ + +S K + H T
Sbjct: 1292 SDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSD-SEESKKPRYRHRLLRHKLTVSDG 1350
Query: 327 HTRSGNLKRPKIGKRFQDS---EFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFL 383
+ +PK K + + SS ED ++ ++ +++ E RP S +
Sbjct: 1351 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1410
Query: 384 EEEPEQRGIEF----------EDESSDRDARPALETQPQQEKQDGEKESELE-------- 425
E E QR + ED SS+ + E + ++E+++ E+E E E
Sbjct: 1411 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1470
Query: 426 --PMNGE------IMDDSLKT---SLITEEEDSTSEVLDEE 455
P G + DD L+T + + EEE+ + + E
Sbjct: 1471 KSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERE 1511
Score = 34.7 bits (78), Expect = 0.29
Identities = 77/389 (19%), Positives = 150/389 (38%), Gaps = 56/389 (14%)
Query: 333 LKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE---- 388
LK+ + + +D + S +G +EK + + K+E S E L E E
Sbjct: 969 LKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHF 1028
Query: 389 QRGI--------EFEDESS---DRDARPALETQPQQEKQDGEKES-----ELEPMNGEIM 432
+GI + E +S D+ ++ E EK G+ +S + + NG
Sbjct: 1029 PKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYG 1088
Query: 433 DDSLKTSLI-----TEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVE---SSKPPEVD 484
+ + L+ ++ S+S+ +K NSS+ + L SSK +
Sbjct: 1089 REKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKE 1148
Query: 485 APDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAH---LGSSDNVATMSNEERSD- 540
+ E D ++ ++K ++ KK + + A +++ SD
Sbjct: 1149 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1208
Query: 541 -GGFPNSVIAEFSEE----PVSENLSPNT-TSSLEDQGEEGVS-----------EPQETS 583
NS+ S+E PV+ENL ++ T + G+E +S + +
Sbjct: 1209 EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPE 1268
Query: 584 TALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQ--FTQSAEKAV--DSSSEE 639
+ + L+E ++ ++ ++ EE + + +Q ++ + A+ V +S S+
Sbjct: 1269 NRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDS 1328
Query: 640 IEVEVPVVDRRNLRRK---AKGHKGPAKK 665
E + P R LR K + G G KK
Sbjct: 1329 EESKKPRYRHRLLRHKLTVSDGESGEEKK 1357
>gi|38261962 activating transcription factor 7 interacting protein
[Homo sapiens]
Length = 1270
Score = 47.4 bits (111), Expect = 4e-05
Identities = 76/332 (22%), Positives = 130/332 (39%), Gaps = 68/332 (20%)
Query: 343 QDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLE--------EEPEQRGIEF 394
+D +F G DEK Q S+++ +++EE LE + P + +
Sbjct: 312 KDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTICSDRPPENEKKV 371
Query: 395 EDE-----SSDRDARPALETQPQQEKQDGEKESEL-EPMNGEIMDDSLKTSLITEEEDS- 447
E++ + DA + Q EK + E ++L E +N +++D+ K+ I E DS
Sbjct: 372 EEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDN-KSENILENTDSM 430
Query: 448 -TSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDE 506
T E++ KL P SED E+ KT +P +DE D
Sbjct: 431 ETDEIIPILEKLAP---SED---------------ELTCFSKTSLLP-----IDETNPDL 467
Query: 507 KGHMEEKLSLLPRKKAHLGSSDNVA--TMSNEERSDGGFPNSVIAEFSEEPVSENLSPN- 563
+ ME P K+ S A +S+EE G E+ SE +S N
Sbjct: 468 EEKMESSFG-SPSKQESSESLPKEAFLVLSDEEDISG-----------EKDESEVISQNE 515
Query: 564 TTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLD 623
T S E + E ++P+E + + + +KN+ + + SE +D
Sbjct: 516 TCSPAEVESNEKDNKPEEEEQVIHED------------DERPSEKNEFSRRKRSKSEDMD 563
Query: 624 QFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRK 655
QS + E E +V + + ++ +K
Sbjct: 564 N-VQSKRRRYMEEEYEAEFQVKITAKGDINQK 594
>gi|21264343 scaffold attachment factor B [Homo sapiens]
Length = 915
Score = 47.0 bits (110), Expect = 6e-05
Identities = 80/368 (21%), Positives = 132/368 (35%), Gaps = 45/368 (12%)
Query: 301 MQLTIDSLKDAFASTSEGHDKTSVSTHTRS-GNLK----RPKIGKRFQDSEFSSS----- 350
M T+ L D+ A+ + S T TR +L+ R ++ KR DS + S
Sbjct: 1 MAETLSGLGDSGAAGAAALSSASSETGTRRLSDLRVIDLRAELRKRNVDSSGNKSVLMER 60
Query: 351 -----QGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARP 405
+ E + +T+ NK T++ S + EE E G+E D
Sbjct: 61 LKKAIEDEGGNPDEIEITSEGNK--KTSKRSSKGRKPEEEGVEDNGLEENSGDGQEDVET 118
Query: 406 ALETQPQQEKQDGEKESELEPMNGEIMD-------DSLKTSLITEEE--DSTSEVLDEEL 456
+LE + D E E NG + D D+L+ SL E + + L E+L
Sbjct: 119 SLENLQDIDIMDISVLDEAEIDNGSVADCVEDDDADNLQESLSDSRELVEGEMKELPEQL 178
Query: 457 KLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTP---RIPD--SEMLMDEGTSDEKGHME 511
+ E NL + + E++ P P +I D E E +E +E
Sbjct: 179 QEHAIEDKETINNLDTSSSDFTILQEIEEPSLEPENEKILDILGETCKSEPVKEESSELE 238
Query: 512 EKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQ 571
+ + + + +G +A E+ D P + + E + S S L
Sbjct: 239 QPFA---QDTSSVGPDRKLA--EEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVV 293
Query: 572 GEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEK 631
E +P + + E V Q + + E +EASSE+L + A
Sbjct: 294 KREPAEQPGDGE---------RTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPS 344
Query: 632 AVDSSSEE 639
S+E
Sbjct: 345 PEARDSKE 352
>gi|24308179 CTTNBP2 N-terminal like [Homo sapiens]
Length = 639
Score = 45.8 bits (107), Expect = 1e-04
Identities = 63/294 (21%), Positives = 118/294 (40%), Gaps = 46/294 (15%)
Query: 315 TSEGHDKTSVSTHTRSG-----NLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKL 369
T+EG D T + R ++ ++ K ++ + SSQ E+E++ L++ + L
Sbjct: 126 TAEGDDVTYMLEKERERLTQQLEFEKSQVKKFEKEQKKLSSQLEEERSRHKQLSSML-VL 184
Query: 370 ESTARPSESSEE-------FLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKES 422
E ++++EE L+ E E+ + +E + + L+T+ Q EKQ E +
Sbjct: 185 ECKKATNKAAEEGQKAGELSLKLEKEKSRVSKLEEELAAERKRGLQTEAQVEKQLSEFDI 244
Query: 423 ELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPE 482
E E + ++ + +T + EE +S +++ ++L+ +SS + P+ V E
Sbjct: 245 EREQLRAKLNREENRTKTLKEEMESLKKIV-KDLEASHQHSSPNEQLKKPVTVSKGTATE 303
Query: 483 VDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGG 542
MLM E P ++ H N+A M+N G
Sbjct: 304 ------------PLMLMSVFCQTES---------FPAERTH---GSNIAKMTNT-----G 334
Query: 543 FPNSVIAEFSEEPVSENLSPNTTSSLE---DQGEEGVSEPQETSTALPQSSLIE 593
P +S + + P ++ E E P+E S AL Q +E
Sbjct: 335 LPGPATPAYSYAKTNGHCDPEIQTTRELTAGNNVENQVPPREKSVALAQEKPVE 388
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 45.8 bits (107), Expect = 1e-04
Identities = 90/450 (20%), Positives = 163/450 (36%), Gaps = 53/450 (11%)
Query: 240 WEVEGVGHWYQRIPVTRALQREA-LKILALSQ---NEPKRPMSGEYGPA---SVPEYEAR 292
WE E Q I TRA R++ K+ + ++ + RP++GE G S E
Sbjct: 1018 WEKEE-----QEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE 1072
Query: 293 TEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIG--KRFQDSEFSSS 350
E+ E + + +D E ++ + + L +P+ KR +
Sbjct: 1073 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKK 1132
Query: 351 QGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQR-----GIEFEDESSDRDARP 405
+G + +S+T E+T +E + EE P + IE E++ R
Sbjct: 1133 RGRKRRRINSSVTTETIS-ETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRK 1191
Query: 406 ALETQPQQEKQDGEKESE-------LEPMNGEIMDDSLKT---SLITEEEDSTSEVLDEE 455
A + QP +++Q E+E + +P + DDS S E +V +
Sbjct: 1192 AFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKG 1251
Query: 456 LKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKG------- 508
K ++ + PPE TP PD ++ ++E +G
Sbjct: 1252 TKRGLSKWRQNKERKTGFKLNLYTPPE------TPMEPDEQVTVEEQKETSEGKTSPSPI 1305
Query: 509 HMEEKL-----SLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPN 563
+EE++ +LLP+++ + + S G P + + EE E
Sbjct: 1306 RIEEEVKETGEALLPQEE---NRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEE 1362
Query: 564 TTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLD 623
E + EEG ++ E E+ +++ + + EE+ E E
Sbjct: 1363 EEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTE--KEDSARLDDHEEEEEEDEEPSH 1420
Query: 624 QFTQSAEKAVDSSSEEIEVEVPVVDRRNLR 653
A+ DS E EVE + R + +
Sbjct: 1421 NEDHDADDEDDSHMESAEVEKEELPRESFK 1450
Score = 45.1 bits (105), Expect = 2e-04
Identities = 84/428 (19%), Positives = 155/428 (36%), Gaps = 71/428 (16%)
Query: 285 SVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNL----KRPKIGK 340
S E EA E + E + + ST ++ +++ L RP G+
Sbjct: 998 SEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGE 1057
Query: 341 RFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSD 400
R Q E S E+E+ E E EE E+E E+ E E+E +
Sbjct: 1058 RGQLLELSKESSEEEEE------------EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105
Query: 401 RDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQP 460
+ P T+PQ ++ L+ G + +S+ TE T+EVL+E P
Sbjct: 1106 IQSSPPRLTKPQSVAIKRKRPFVLKKKRGR-KRRRINSSVTTETISETTEVLNE-----P 1159
Query: 461 FNSSEDSTNLVPL-------VVESSKPPEV-----DAPDKTPRIPDSE------------ 496
F++S++ + L V E + P + P K + + E
Sbjct: 1160 FDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADP 1219
Query: 497 ---MLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSE 553
+ D+ ++ ++G + L ++ G+ ++ + GF ++
Sbjct: 1220 CRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYT---- 1275
Query: 554 EPVSENLSPNTTSSLEDQGE--EGVSEP---------QETSTALPQSSLIEVELEDVPFS 602
P + P+ ++E+Q E EG + P +ET AL E P S
Sbjct: 1276 -PPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVS 1334
Query: 603 QNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGP 662
N + E+ E+ ++ + E+ + EE E N+ + G K
Sbjct: 1335 PNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEE------GGGNVEKDPDGAKSQ 1388
Query: 663 AKKKAKLT 670
K++ +++
Sbjct: 1389 EKEEPEIS 1396
Score = 40.0 bits (92), Expect = 0.007
Identities = 80/343 (23%), Positives = 130/343 (37%), Gaps = 62/343 (18%)
Query: 294 EDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGE 353
E + Q+T++ K+ TSEG KTS S +I + +++ + E
Sbjct: 1278 ETPMEPDEQVTVEEQKE----TSEG--KTSPSPI---------RIEEEVKETGEALLPQE 1322
Query: 354 DEKTSQTSLTASINKL------ESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPAL 407
+ + +T S N + +P E EE EEE E+ E E+E +
Sbjct: 1323 ENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDP 1382
Query: 408 ETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDS 467
+ QEK++ E +E E DS + EEE+ E E ED
Sbjct: 1383 DGAKSQEKEEPEISTEKE--------DSARLDDHEEEEEEDEEPSHNE---DHDADDEDD 1431
Query: 468 TNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSS 527
+++ VE + P + + + E +D + + GH P G
Sbjct: 1432 SHMESAEVEKEELPRESFKEV---LENQETFLD--LNVQPGHSN------PEVLMDCG-V 1479
Query: 528 DNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALP 587
D A+ ++E + G P +V E EEP P + +DQ S+ +T
Sbjct: 1480 DLTASCNSEPKELAGDPEAV-PESDEEP-----PPGEQAQKQDQKN---SKEVDTEFKEG 1530
Query: 588 QSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAE 630
+ +E++ E V Q+ Q+ SSEQ D F AE
Sbjct: 1531 NPATMEIDSETVQAVQSLTQE---------SSEQDDTFQDCAE 1564
Score = 38.9 bits (89), Expect = 0.016
Identities = 84/366 (22%), Positives = 144/366 (39%), Gaps = 40/366 (10%)
Query: 324 VSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFL 383
VS +T G + K ++ E + E+E+ + +E ++S E+
Sbjct: 1333 VSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEK-- 1390
Query: 384 EEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITE 443
EEPE I E E S R L+ ++E++D E+ S E + + DDS S E
Sbjct: 1391 -EEPE---ISTEKEDSAR-----LDDHEEEEEED-EEPSHNEDHDADDEDDSHMESAEVE 1440
Query: 444 EED----STSEVLDEE-----LKLQPFNSSEDSTNL--VPLVVESSKPPEVDAPDKTPRI 492
+E+ S EVL+ + L +QP +S+ + V L + P+ A D +
Sbjct: 1441 KEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEA-V 1499
Query: 493 PDSEMLMDEGTS----DEKGHMEEKLSLLPRKKAHLG-SSDNVATMSN--EERSDGGFPN 545
P+S+ G D+K E A + S+ V + + +E S+
Sbjct: 1500 PESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTF 1559
Query: 546 SVIAEFSEEPVS------ENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDV 599
AE E S + SP ++L+D + S P + + P S+ V V
Sbjct: 1560 QDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSV 1619
Query: 600 PFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIE--VEVPVVDRRNLRRKAK 657
P +N+ S +QS S L S V S S+ + V+ D ++ +
Sbjct: 1620 PALENS-YAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTE 1678
Query: 658 GHKGPA 663
++ P+
Sbjct: 1679 NYENPS 1684
>gi|190194423 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 45.8 bits (107), Expect = 1e-04
Identities = 63/287 (21%), Positives = 117/287 (40%), Gaps = 44/287 (15%)
Query: 363 TASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPAL-----ETQPQQEKQD 417
TA ++TA PS +E EE ++ + ED+S + + ++ E+ Q +Q
Sbjct: 31 TAETVAPDNTAIPSLRAEA--EENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAEQG 88
Query: 418 GEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVES 477
EL + E D L +L + T ++ ++ + Q SE++ L P V
Sbjct: 89 KSSSQELGLKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSF 148
Query: 478 SKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEE 537
+ + ++ K +E + + +L+ R H S + N+E
Sbjct: 149 TDSNQQESITKR----------EENQEQPRNYSHHQLN---RSSKH---SQGLRDQGNQE 192
Query: 538 RSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGV-SEPQETSTALPQSSLIEVEL 596
+ PN E EE ++ GE G ++ QE T LP+ +
Sbjct: 193 QD----PNISNGEEEEE--------------KEPGEVGTHNDNQERKTELPREHANSKQE 234
Query: 597 EDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVE 643
ED +Q+ +S++ ++ S Q D+F Q ++ D+S+ E+E E
Sbjct: 235 EDN--TQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEE 279
Score = 32.7 bits (73), Expect = 1.1
Identities = 55/255 (21%), Positives = 97/255 (38%), Gaps = 31/255 (12%)
Query: 339 GKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDES 398
G + QD S+ + E+EK T + N+ T P E + EE+ Q D+
Sbjct: 189 GNQEQDPNISNGEEEEEKEPGEVGTHNDNQERKTELPREHANSKQEEDNTQ-----SDDI 243
Query: 399 SDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLK--TSLITEEEDSTSEVLDEEL 456
+ +P ++ Q+++ D + + + N E+ +++ I E E + E
Sbjct: 244 LEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEENASNVNKHIQETEWQSQEGKTGLE 303
Query: 457 KLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPR----IPDSEMLMDEGTSDEKGHMEE 512
+ +E+ T L++E + D + TPR D + D+G +D H
Sbjct: 304 AISNHKETEEKTVSEALLMEPT-----DDGNTTPRNHGVDDDGDDDGDDGGTDGPRHSAS 358
Query: 513 KLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQ- 571
+P + A + E + + E E V EN + TT E Q
Sbjct: 359 DDYFIPSQ----------AFLEAERAQSIAYHLKI--EEQREKVHENENIGTTEPGEHQE 406
Query: 572 --GEEGVSEPQETST 584
E S +ETS+
Sbjct: 407 AKKAENSSNEEETSS 421
>gi|190341024 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 45.8 bits (107), Expect = 1e-04
Identities = 63/287 (21%), Positives = 117/287 (40%), Gaps = 44/287 (15%)
Query: 363 TASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPAL-----ETQPQQEKQD 417
TA ++TA PS +E EE ++ + ED+S + + ++ E+ Q +Q
Sbjct: 31 TAETVAPDNTAIPSLRAEA--EENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAEQG 88
Query: 418 GEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVES 477
EL + E D L +L + T ++ ++ + Q SE++ L P V
Sbjct: 89 KSSSQELGLKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSF 148
Query: 478 SKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEE 537
+ + ++ K +E + + +L+ R H S + N+E
Sbjct: 149 TDSNQQESITKR----------EENQEQPRNYSHHQLN---RSSKH---SQGLRDQGNQE 192
Query: 538 RSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGV-SEPQETSTALPQSSLIEVEL 596
+ PN E EE ++ GE G ++ QE T LP+ +
Sbjct: 193 QD----PNISNGEEEEE--------------KEPGEVGTHNDNQERKTELPREHANSKQE 234
Query: 597 EDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVE 643
ED +Q+ +S++ ++ S Q D+F Q ++ D+S+ E+E E
Sbjct: 235 EDN--TQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEE 279
Score = 32.7 bits (73), Expect = 1.1
Identities = 55/255 (21%), Positives = 97/255 (38%), Gaps = 31/255 (12%)
Query: 339 GKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDES 398
G + QD S+ + E+EK T + N+ T P E + EE+ Q D+
Sbjct: 189 GNQEQDPNISNGEEEEEKEPGEVGTHNDNQERKTELPREHANSKQEEDNTQ-----SDDI 243
Query: 399 SDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLK--TSLITEEEDSTSEVLDEEL 456
+ +P ++ Q+++ D + + + N E+ +++ I E E + E
Sbjct: 244 LEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEENASNVNKHIQETEWQSQEGKTGLE 303
Query: 457 KLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPR----IPDSEMLMDEGTSDEKGHMEE 512
+ +E+ T L++E + D + TPR D + D+G +D H
Sbjct: 304 AISNHKETEEKTVSEALLMEPT-----DDGNTTPRNHGVDDDGDDDGDDGGTDGPRHSAS 358
Query: 513 KLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQ- 571
+P + A + E + + E E V EN + TT E Q
Sbjct: 359 DDYFIPSQ----------AFLEAERAQSIAYHLKI--EEQREKVHENENIGTTEPGEHQE 406
Query: 572 --GEEGVSEPQETST 584
E S +ETS+
Sbjct: 407 AKKAENSSNEEETSS 421
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 45.4 bits (106), Expect = 2e-04
Identities = 72/306 (23%), Positives = 125/306 (40%), Gaps = 34/306 (11%)
Query: 339 GKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESS-EEFLEE---EPEQRGIEF 394
G R DS +S + + S S +K+ + + + EE ++E E + G EF
Sbjct: 381 GLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEF 440
Query: 395 EDESSDRDARPALETQPQQEKQDGEKESELE---PMNGEIMDDSLKTS-----LITEEED 446
E+ +S+ +A+ E+ P++E ++G E E E P G S K S + EED
Sbjct: 441 EEGASENNAK---ESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEED 497
Query: 447 STSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDA-PDKTPRIPDSEMLMDEGTSD 505
S + E K N E++ + +K E + P K DSE DE S+
Sbjct: 498 SPKK---ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSE 554
Query: 506 EKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTT 565
++ + + + +EE S+ +V+ + EE SEN
Sbjct: 555 KQSEDGSEREF---------EENGLEKDLDEEGSEKELHENVLDKELEENDSEN------ 599
Query: 566 SSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQF 625
S ED G E V + + + + S + E ED + ++ E++ A + L+
Sbjct: 600 SEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAA 659
Query: 626 TQSAEK 631
+ AE+
Sbjct: 660 DKKAEE 665
Score = 43.1 bits (100), Expect = 8e-04
Identities = 53/252 (21%), Positives = 96/252 (38%), Gaps = 21/252 (8%)
Query: 336 PKIGKRFQDSEFSSSQG-------EDEKTSQTSLTASINKLESTARPSESSEEFLEEEPE 388
PK G S+ S +G ED ++ N E ES ++ +E E
Sbjct: 472 PKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEE 531
Query: 389 QRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDST 448
+ G E E D + + +Q + E+E E + ++ ++ E++
Sbjct: 532 EVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEG-------SEKELH 584
Query: 449 SEVLDEELKLQPFNSSE---DSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSD 505
VLD+EL+ +SE D + V S + + D+ +K E + D+ SD
Sbjct: 585 ENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDD-ESD 643
Query: 506 EK---GHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSP 562
EK + +EK KKA G +D ++++ D + + E+ ++ S
Sbjct: 644 EKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSN 703
Query: 563 NTTSSLEDQGEE 574
E+ E
Sbjct: 704 EKLFDEEEDSSE 715
Score = 36.6 bits (83), Expect = 0.077
Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 11/123 (8%)
Query: 343 QDSEFSSSQGE---DEKTSQTSLTASINKLESTARP------SESSEEFLEEEPEQRGIE 393
++SEF E DE+ S+ ++ E ES E+ EE +++G+E
Sbjct: 598 ENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLE 657
Query: 394 FEDESSDR-DARPALETQPQQEKQDGEKESELEPMNGEIM-DDSLKTSLITEEEDSTSEV 451
D+ ++ DA L + ++ + E+E + ++ DD L EEEDS+ ++
Sbjct: 658 AADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717
Query: 452 LDE 454
D+
Sbjct: 718 FDD 720
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,890,530
Number of Sequences: 37866
Number of extensions: 1241440
Number of successful extensions: 8316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 592
Number of HSP's that attempted gapping in prelim test: 5758
Number of HSP's gapped (non-prelim): 2040
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.