Search of human proteins with 153070252

Search of human proteins with 153070252

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153070252 MAGI family member, X-linked isoform c [Homo
sapiens]
         (258 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153070252 MAGI family member, X-linked isoform c [Homo sapiens]    516   e-147
gi|153070256 MAGI family member, X-linked isoform d [Homo sapiens]    498   e-141
gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]    342   2e-94
gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]    331   4e-91
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom...    54   2e-07
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]              50   1e-06
gi|218505835 membrane-associated guanylate kinase-related  3 iso...    50   2e-06
gi|155969695 membrane-associated guanylate kinase-related  3 iso...    50   2e-06
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom...    48   1e-05
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]              47   2e-05
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]              47   2e-05
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]             47   2e-05
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]              47   2e-05
gi|112363080 microtubule associated serine/threonine kinase 2 [H...    44   1e-04
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom...    44   1e-04
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]              43   2e-04
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom...    42   5e-04
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             42   5e-04
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]              42   5e-04
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]               42   5e-04
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i...    42   7e-04
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i...    42   7e-04
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i...    42   7e-04
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is...    42   7e-04
gi|5803177 basic beta 2 syntrophin [Homo sapiens]                      41   0.001
gi|150170729 microtubule associated serine/threonine kinase 3 [H...    41   0.001
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               41   0.001
gi|4507137 acidic alpha 1 syntrophin [Homo sapiens]                    40   0.002
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]              40   0.002
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    40   0.003

>gi|153070252 MAGI family member, X-linked isoform c [Homo sapiens]
          Length = 258

 Score =  516 bits (1330), Expect = e-147
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MEPRTGGAANPKGSRGSRGPSPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATLR 60
           MEPRTGGAANPKGSRGSRGPSPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATLR
Sbjct: 1   MEPRTGGAANPKGSRGSRGPSPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATLR 60

Query: 61  LRRKEAVSVLDSADIEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRA 120
           LRRKEAVSVLDSADIEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRA
Sbjct: 61  LRRKEAVSVLDSADIEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRA 120

Query: 121 GGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHP 180
           GGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHP
Sbjct: 121 GGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHP 180

Query: 181 PSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALG 240
           PSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALG
Sbjct: 181 PSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALG 240

Query: 241 VRGAAQLAQEMAAGRRRH 258
           VRGAAQLAQEMAAGRRRH
Sbjct: 241 VRGAAQLAQEMAAGRRRH 258


>gi|153070256 MAGI family member, X-linked isoform d [Homo sapiens]
          Length = 253

 Score =  498 bits (1281), Expect = e-141
 Identities = 253/258 (98%), Positives = 253/258 (98%), Gaps = 5/258 (1%)

Query: 1   MEPRTGGAANPKGSRGSRGPSPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATLR 60
           MEPRTGGAANPKGSRGSRGPSPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATLR
Sbjct: 1   MEPRTGGAANPKGSRGSRGPSPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATLR 60

Query: 61  LRRKEAVSVLDSADIEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRA 120
           LRRKEAVSVLDSADIEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRA
Sbjct: 61  LRRKEAVSVLDSADIEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRA 120

Query: 121 GGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHP 180
           GGPQLHLVIRRPLETHPGKPRGVGEPRKGV     DRSPDPGGPEVTGSRSSSTSLVQHP
Sbjct: 121 GGPQLHLVIRRPLETHPGKPRGVGEPRKGV-----DRSPDPGGPEVTGSRSSSTSLVQHP 175

Query: 181 PSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALG 240
           PSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALG
Sbjct: 176 PSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALG 235

Query: 241 VRGAAQLAQEMAAGRRRH 258
           VRGAAQLAQEMAAGRRRH
Sbjct: 236 VRGAAQLAQEMAAGRRRH 253


>gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]
          Length = 334

 Score =  342 bits (876), Expect = 2e-94
 Identities = 166/168 (98%), Positives = 167/168 (99%)

Query: 91  RPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGV 150
           R +VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGV
Sbjct: 167 RLEVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGV 226

Query: 151 VPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPE 210
           VPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPE
Sbjct: 227 VPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPE 286

Query: 211 RRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGAAQLAQEMAAGRRRH 258
           RRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGAAQLAQEMAAGRRRH
Sbjct: 287 RRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGAAQLAQEMAAGRRRH 334


>gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]
          Length = 262

 Score =  331 bits (848), Expect = 4e-91
 Identities = 182/254 (71%), Positives = 183/254 (72%), Gaps = 66/254 (25%)

Query: 66  AVSVLDSADIEVTDSRLPHATIVDHRPQ-------------------------------- 93
           AVSVLDSADIEVTDSRLPHATIVDHRPQ                                
Sbjct: 14  AVSVLDSADIEVTDSRLPHATIVDHRPQGKARSAPKPSQASGHFSVELVRGYAGFGLTLG 73

Query: 94  -----VGDLVLHING------------------------ESTQGLTHAQAVERIRAGGPQ 124
                 GD  L + G                        ESTQGLTHAQAVERIRAGGPQ
Sbjct: 74  GGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTHAQAVERIRAGGPQ 133

Query: 125 LHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRT 184
           LHLVIRRPLETHPGKPRGVGEPRKGV     DRSPDPGGPEVTGSRSSSTSLVQHPPSRT
Sbjct: 134 LHLVIRRPLETHPGKPRGVGEPRKGV-----DRSPDPGGPEVTGSRSSSTSLVQHPPSRT 188

Query: 185 TLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGA 244
           TLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGA
Sbjct: 189 TLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGA 248

Query: 245 AQLAQEMAAGRRRH 258
           AQLAQEMAAGRRRH
Sbjct: 249 AQLAQEMAAGRRRH 262


>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
            containing 2 [Homo sapiens]
          Length = 1455

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 18/180 (10%)

Query: 91   RPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR----------------PLE 134
            R +VGD ++ INGEST+ +THA+A+E I++GG ++ L+++R                P  
Sbjct: 1187 RMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYDEPAPWSSPAA 1246

Query: 135  THPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPE 194
              PG P        G+ P  P     P  P    S   +  + +    R   K+     +
Sbjct: 1247 AAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKP-KELSACGQ 1305

Query: 195  PSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGAAQLAQEMAAG 254
                        + P+R A    ++ PG  G          +RA G+  AA  A    AG
Sbjct: 1306 KKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGL-AAADAADAARAG 1364



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 12/90 (13%)

Query: 95  GDLVLHINGESTQGLTHAQAVERIR--AGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVP 152
           GDL++ IN ++ Q L+H + V+ ++    G +  L+I R          G   P K   P
Sbjct: 643 GDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSLIIHR---------GGFFSPWKTPKP 693

Query: 153 SWPDRSPDPGGPEVTGSRSSSTSLVQHPPS 182
              DR  + G P+ + S  +    +  PP+
Sbjct: 694 IM-DRWENQGSPQTSLSAPAIPQNLPFPPA 722



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 9/57 (15%)

Query: 82   LPH--ATIVDHRP-------QVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVI 129
            +PH    I+D  P       +VGD +L +NG+S   + HA  V+ I+  G  + L I
Sbjct: 950  VPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 1006



 Score = 28.1 bits (61), Expect = 7.9
 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 4/56 (7%)

Query: 89  DHRPQVGDLVLHINGESTQGLTHAQAVERIRAG--GPQLHLVIRR--PLETHPGKP 140
           D + + GD++++IN     G THA  V+  ++   G  ++LV+ R  PL   P  P
Sbjct: 464 DGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDP 519


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 45/152 (29%), Positives = 65/152 (42%), Gaps = 21/152 (13%)

Query: 94  VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR--PLETHPGKPRGVG-EPRKGV 150
           VGD VL I+GE+   LTH +A  +IRA G +L L + R  P+++ P K +    +P + +
Sbjct: 46  VGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKVQTPDKQPLRPL 105

Query: 151 VP---------SWPDRSPDPGGPEVTGSR----SSSTSLVQHPPSRTTLKKTRGSPEPSP 197
           VP         +  D  P PG  +    R     + T  +Q P      K ++      P
Sbjct: 106 VPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQ-----VP 160

Query: 198 EAAADGPTVSPPERRAEDPNDQIPGSPGPWLV 229
              A  P  S P+     P    P S  PW V
Sbjct: 161 RTEAPAPASSTPQEPWPGPTAPSPTSRPPWAV 192


>gi|218505835 membrane-associated guanylate kinase-related  3 isoform
            1 [Homo sapiens]
          Length = 1481

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 23/44 (52%), Positives = 33/44 (75%)

Query: 87   IVDHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIR 130
            I D R  VGD ++ INGE TQG+TH +A+E I+AGG ++ L++R
Sbjct: 1057 IKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLR 1100



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 93  QVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRK 148
           +VGD +  +NG+S   L+H   V+ I+  G  + L +    E H G P G    R+
Sbjct: 898 KVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAE-EEHHGPPSGTNSARQ 952



 Score = 31.2 bits (69), Expect = 0.93
 Identities = 28/109 (25%), Positives = 41/109 (37%), Gaps = 5/109 (4%)

Query: 135  THPGKPRGVGEPRKG--VVPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGS 192
            T+    + V E  KG  V       S D  G  V   + S   L Q P  +    KT   
Sbjct: 1371 TNKTTSKEVSENEKGKKVTTGETSSSNDKIGENV---QLSEKRLKQEPEEKVVSNKTEDH 1427

Query: 193  PEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALGV 241
                 EAA         +  +  P  +   +PGPW VPS  +++  +G+
Sbjct: 1428 KGKELEAADKNKETGRFKPESSSPVKKTLITPGPWKVPSGNKVTGTIGM 1476


>gi|155969695 membrane-associated guanylate kinase-related  3 isoform
            2 [Homo sapiens]
          Length = 1125

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 23/44 (52%), Positives = 33/44 (75%)

Query: 87   IVDHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIR 130
            I D R  VGD ++ INGE TQG+TH +A+E I+AGG ++ L++R
Sbjct: 1057 IKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLR 1100



 Score = 32.0 bits (71), Expect = 0.55
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 93  QVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRK 148
           +VGD +  +NG+S   L+H   V+ I+  G  + L +    E H G P G    R+
Sbjct: 898 KVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAE-EEHHGPPSGTNSARQ 952


>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
            containing 1 isoform c [Homo sapiens]
          Length = 1462

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 48/169 (28%), Positives = 71/169 (42%), Gaps = 52/169 (30%)

Query: 93   QVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR---------PLETHPGK---P 140
            ++GD +L INGE+T+ + H++A+E I+ GG ++ L ++R         P     G    P
Sbjct: 1165 RIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKRGDGSVPEYDPSSDRHGPATGP 1224

Query: 141  RGVGEPRKGVVPSWPDRSPDPG---------------------GPEVTGSRSSSTSLVQH 179
            +GV E R G     PDR   P                        +  GSR  S    +H
Sbjct: 1225 QGVPEVRAG-----PDRRQHPSLESSYPPDLHKSSPHGEKRAHARDPKGSREYSRQPNEH 1279

Query: 180  PP-SRTTLKKTRGSPEP---SPE----------AAADGPTVSPPERRAE 214
               + T+ K   G+  P   +PE          AAA+GP    PE+R E
Sbjct: 1280 HTWNGTSRKPDSGACRPKDRAPEGRRDAQAERAAAANGPKRRSPEKRRE 1328



 Score = 31.6 bits (70), Expect = 0.72
 Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 29/143 (20%)

Query: 95  GDLVLHINGESTQGLTHAQAVERI--RAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVP 152
           GDL++ +N ++ Q LTH Q V+ +     G ++ L+++R                 G +P
Sbjct: 683 GDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTLLVQR-----------------GGLP 725

Query: 153 SWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPERR 212
             P +SP     E   S++SS   V    S  T      SP  S +   + P   P E +
Sbjct: 726 V-PKKSPKSQPLERKDSQNSSQHSVSSHRSLHT-----ASPSHSTQVLPEFP---PAEAQ 776

Query: 213 AEDPNDQI-PGSPGPWLVPSEER 234
           A D  D      P P+ + ++ R
Sbjct: 777 APDQTDSSGQKKPDPFKIWAQSR 799


>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
          Length = 278

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 26/152 (17%)

Query: 89  DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRK 148
           D RP  GD+++ INGES +G+ HA+A  +IR     L L + R   T PG+  G      
Sbjct: 42  DLRP--GDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG------ 93

Query: 149 GVVPSWPDRSPDPGGPEVTGS----RSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGP 204
                  D S +       GS      S +SL     S T+L    GSP   P +++   
Sbjct: 94  -------DSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSPRAGSPFSPPPSSSSLT 146

Query: 205 TVSPPERRAEDPNDQIPGSPGPWLVPSEERLS 236
             +   R  +     +  SPG   +P+ +RLS
Sbjct: 147 GEAAISRSFQ----SLACSPG---LPAADRLS 171


>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
          Length = 366

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 26/152 (17%)

Query: 89  DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRK 148
           D RP  GD+++ INGES +G+ HA+A  +IR     L L + R   T PG+  G      
Sbjct: 42  DLRP--GDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG------ 93

Query: 149 GVVPSWPDRSPDPGGPEVTGS----RSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGP 204
                  D S +       GS      S +SL     S T+L    GSP   P +++   
Sbjct: 94  -------DSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSPRAGSPFSPPPSSSSLT 146

Query: 205 TVSPPERRAEDPNDQIPGSPGPWLVPSEERLS 236
             +   R  +     +  SPG   +P+ +RLS
Sbjct: 147 GEAAISRSFQ----SLACSPG---LPAADRLS 171


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 52/193 (26%), Positives = 85/193 (44%), Gaps = 39/193 (20%)

Query: 93  QVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR--------PLETHPGKPRGVG 144
           ++GD+VL I+G + QG+TH +A  +I+     L++ ++R        P+    G+P+ V 
Sbjct: 45  RIGDVVLSIDGINAQGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVV 104

Query: 145 EPRKGVVPSWP----------DRSPDPGG----PEVTGSRSSSTSLVQHPPSRTTLKKTR 190
           +P     P+            +++P P G    P+VT   S S++     P+  T   T 
Sbjct: 105 KPVPITSPAVSKVTSTNNMAYNKAPRPFGSVSSPKVTSIPSPSSAFT---PAHAT---TS 158

Query: 191 GSPEPSPEAAADGP--TVSPPERRAEDPNDQIPG--SPGPWL--VPSEERLSRALGVRGA 244
               PSP AA   P    S     A    DQ P   S G     VP +  ++        
Sbjct: 159 SHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTAVNVPRQPTVTSV-----C 213

Query: 245 AQLAQEMAAGRRR 257
           ++ +QE+A G+RR
Sbjct: 214 SETSQELAEGQRR 226


>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
          Length = 352

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 26/152 (17%)

Query: 89  DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRK 148
           D RP  GD+++ INGES +G+ HA+A  +IR     L L + R   T PG+  G      
Sbjct: 42  DLRP--GDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG------ 93

Query: 149 GVVPSWPDRSPDPGGPEVTGS----RSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGP 204
                  D S +       GS      S +SL     S T+L    GSP   P +++   
Sbjct: 94  -------DSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSPRAGSPFSPPPSSSSLT 146

Query: 205 TVSPPERRAEDPNDQIPGSPGPWLVPSEERLS 236
             +   R  +     +  SPG   +P+ +RLS
Sbjct: 147 GEAAISRSFQ----SLACSPG---LPAADRLS 171


>gi|112363080 microtubule associated serine/threonine kinase 2 [Homo
            sapiens]
          Length = 1798

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 52/204 (25%), Positives = 82/204 (40%), Gaps = 24/204 (11%)

Query: 21   SPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATLRLRRKEAVSVLDSADIEVTDS 80
            S  + PS+R      D  P  A  ++    ++ RAG       +     +  +D+     
Sbjct: 1078 SQSSNPSSRDSSPSRDFLP--ALGSMRPPIIIHRAGKKYGFTLRAIRVYMGDSDVYTVHH 1135

Query: 81   RLPHATIVDHRP------QVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
             + H  + D  P      + GDL+ H+NGE   GL H + VE I   G ++  +   PLE
Sbjct: 1136 MVWH--VEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELILKSGNKV-AISTTPLE 1192

Query: 135  THPGKPRGVGEPRKGVVPS-WPDRSPDPGGPEVTGSRSSST---------SLVQHPPSRT 184
                K   VG  RKG   +    RS    G +   SR  S+         SL+    S +
Sbjct: 1193 NTSIK---VGPARKGSYKAKMARRSKRSRGKDGQESRKRSSLFRKITKQASLLHTSRSLS 1249

Query: 185  TLKKTRGSPEPSPEAAADGPTVSP 208
            +L ++  S E  P +     ++SP
Sbjct: 1250 SLNRSLSSGESGPGSPTHSHSLSP 1273


>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
            containing 1 isoform b [Homo sapiens]
          Length = 1256

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 4/67 (5%)

Query: 93   QVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVP 152
            ++GD +L INGE+T+ + H++A+E I+ GG ++ L ++R      G     G      +P
Sbjct: 1194 RIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKR----GDGSVPEYGGSNYENIP 1249

Query: 153  SWPDRSP 159
            S+P  +P
Sbjct: 1250 SFPGMTP 1256



 Score = 31.6 bits (70), Expect = 0.72
 Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 29/143 (20%)

Query: 95  GDLVLHINGESTQGLTHAQAVERI--RAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVP 152
           GDL++ +N ++ Q LTH Q V+ +     G ++ L+++R                 G +P
Sbjct: 683 GDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTLLVQR-----------------GGLP 725

Query: 153 SWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPERR 212
             P +SP     E   S++SS   V    S  T      SP  S +   + P   P E +
Sbjct: 726 V-PKKSPKSQPLERKDSQNSSQHSVSSHRSLHT-----ASPSHSTQVLPEFP---PAEAQ 776

Query: 213 AEDPNDQI-PGSPGPWLVPSEER 234
           A D  D      P P+ + ++ R
Sbjct: 777 APDQTDSSGQKKPDPFKIWAQSR 799


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 47/186 (25%), Positives = 67/186 (36%), Gaps = 55/186 (29%)

Query: 94  VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR--PLETHPGK------------ 139
           VGD VL I+GE+   LTH +A  +IRA G +L L + R  P+++ P K            
Sbjct: 46  VGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYT 105

Query: 140 -----------------------PRGVGEPRKGVVP---------SWPDRSPDPGGPEVT 167
                                  P+  G+P + +VP         +  D  P PG  +  
Sbjct: 106 FAPSVSLNKTARPFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSR 165

Query: 168 GSR----SSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGS 223
             R     + T  +Q P      K ++      P   A  P  S P+     P    P S
Sbjct: 166 SFRILAHLTGTEFMQDPDEEHLKKSSQ-----VPRTEAPAPASSTPQEPWPGPTAPSPTS 220

Query: 224 PGPWLV 229
             PW V
Sbjct: 221 RPPWAV 226


>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
            containing 1 isoform a [Homo sapiens]
          Length = 1287

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 16/39 (41%), Positives = 30/39 (76%)

Query: 93   QVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR 131
            ++GD +L INGE+T+ + H++A+E I+ GG ++ L ++R
Sbjct: 1193 RIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKR 1231



 Score = 31.6 bits (70), Expect = 0.72
 Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 29/143 (20%)

Query: 95  GDLVLHINGESTQGLTHAQAVERI--RAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVP 152
           GDL++ +N ++ Q LTH Q V+ +     G ++ L+++R                 G +P
Sbjct: 683 GDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTLLVQR-----------------GGLP 725

Query: 153 SWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPERR 212
             P +SP     E   S++SS   V    S  T      SP  S +   + P   P E +
Sbjct: 726 V-PKKSPKSQPLERKDSQNSSQHSVSSHRSLHT-----ASPSHSTQVLPEFP---PAEAQ 776

Query: 213 AEDPNDQI-PGSPGPWLVPSEER 234
           A D  D      P P+ + ++ R
Sbjct: 777 APDQTDSSGQKKPDPFKIWAQSR 799


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 39/133 (29%), Positives = 50/133 (37%), Gaps = 21/133 (15%)

Query: 138 GKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQ----HPPSRTTLKKTRGSP 193
           G  R V +  +   P  PD    P GP     R + T   +     P    T   T  +P
Sbjct: 430 GPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAP 489

Query: 194 EPS---------PEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGA 244
            P          P AA++GP  SPP   AE P    P  PGP  + +E     A   R  
Sbjct: 490 SPPAPKSCLKHRPAAASEGPAASPPLAAAESP----PVEPGPGSLDAE----AAAPERPK 541

Query: 245 AQLAQEMAAGRRR 257
           A+ A+   AG  R
Sbjct: 542 AERAEAPPAGAER 554



 Score = 36.2 bits (82), Expect = 0.029
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 8/89 (8%)

Query: 146 PRKGVVPSWPDRSPDPGGP---EVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAAD 202
           P  G     PDR P+PG P      G   +  + +QH  + T   +  G P   P +   
Sbjct: 278 PSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPA 337

Query: 203 GPTVSPPER----RAEDPN-DQIPGSPGP 226
            P ++ PE     R E P+  + P +PGP
Sbjct: 338 TPELAEPESAPTLRVEPPSPPEGPPNPGP 366



 Score = 34.7 bits (78), Expect = 0.085
 Identities = 45/174 (25%), Positives = 58/174 (33%), Gaps = 38/174 (21%)

Query: 120 AGGPQLHLVIRRPLETHPG------------KPRGVGEPRKGVVPSWPDRSPDPGGPEVT 167
           A  P L      P+E  PG            K      P  G   + P+R  + GG E+ 
Sbjct: 510 AASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELR 569

Query: 168 GSRSSSTSL--------VQHPPSRTT--LKKTRGSPE-------------PSPEAAADGP 204
           G++  S S         V  P  R +  L   R  P              P P+ A  GP
Sbjct: 570 GAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGP 629

Query: 205 TVSPPERRAEDPNDQIPGSPGPWLVPSEERLSRALGVRGAAQLAQEMAAGRRRH 258
                ER  +D  D+     GP   P E   + A G R     AQE A    R+
Sbjct: 630 R-KLAERGPQDSGDRAASPAGPRKSPQE--AAAAPGTREPCPAAQEPAPSEDRN 680


>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
          Length = 977

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 38/130 (29%), Positives = 53/130 (40%), Gaps = 14/130 (10%)

Query: 101 INGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPR----GVGEPRKGVVPSWPD 156
           +NGE  Q    AQ+        P+  ++   PL      PR    G G P     PS  +
Sbjct: 414 LNGEGLQSPPRAQSAP------PEAAVLPPSPLPAPVASPRPFQPGGGAPTPA--PSIFN 465

Query: 157 RSPDPGGPEVTGSRSSSTSLVQHP--PSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAE 214
           RS  P  P + G R ++TS++  P  P R        SP P P  ++ GPT  P      
Sbjct: 466 RSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGV 525

Query: 215 DPNDQIPGSP 224
             +  + GSP
Sbjct: 526 PSHAPVSGSP 535



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 42/138 (30%), Positives = 57/138 (41%), Gaps = 14/138 (10%)

Query: 96  DLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWP 155
           D +L ING S   L+HA A+  I A G QL L ++R  +  P +     E +  V+    
Sbjct: 51  DQLLAINGVSCTNLSHASAMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQ--VLSPLS 108

Query: 156 DRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAED 215
             SP+P G  V        SL   P S     +T        ++ ADGP      RR   
Sbjct: 109 PLSPEPPGAPVPQPLQPG-SLRSPPDSEAYYGET--------DSDADGPATQEKPRR--- 156

Query: 216 PNDQIPGSPGPWLVPSEE 233
           P  + P  P P   P +E
Sbjct: 157 PRRRGPTRPTPPGAPPDE 174



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 7/105 (6%)

Query: 151 VPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPT----V 206
           VPS    S  P  P  +G  ++++SL    PSR         P   P AAA   T    +
Sbjct: 525 VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFL 584

Query: 207 SPPERRAEDPNDQIPGSPGPWLVPS--EERLSRALGVRGAAQLAQ 249
           S P R +  P    PG PG    PS  E+R+S      G  Q A+
Sbjct: 585 SAPLRPSARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEAR 628



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 34/104 (32%), Positives = 35/104 (33%), Gaps = 11/104 (10%)

Query: 120 AGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPD---PGGPEVTGSRSSSTS- 175
           A GP      RRP    P +P   G P   V  S     P    PG P    SR SS S 
Sbjct: 145 ADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSW 204

Query: 176 ---LVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSP-PERRAED 215
                  PP    L    G   P P      P V P P   AED
Sbjct: 205 EDGAALQPPPAEALLLPHGPLRPGPHLI---PMVGPVPHPVAED 245


>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
          Length = 753

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 38/130 (29%), Positives = 53/130 (40%), Gaps = 14/130 (10%)

Query: 101 INGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPR----GVGEPRKGVVPSWPD 156
           +NGE  Q    AQ+        P+  ++   PL      PR    G G P     PS  +
Sbjct: 190 LNGEGLQSPPRAQSAP------PEAAVLPPSPLPAPVASPRPFQPGGGAPTPA--PSIFN 241

Query: 157 RSPDPGGPEVTGSRSSSTSLVQHP--PSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAE 214
           RS  P  P + G R ++TS++  P  P R        SP P P  ++ GPT  P      
Sbjct: 242 RSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGV 301

Query: 215 DPNDQIPGSP 224
             +  + GSP
Sbjct: 302 PSHAPVSGSP 311



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 7/105 (6%)

Query: 151 VPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPT----V 206
           VPS    S  P  P  +G  ++++SL    PSR         P   P AAA   T    +
Sbjct: 301 VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFL 360

Query: 207 SPPERRAEDPNDQIPGSPGPWLVPS--EERLSRALGVRGAAQLAQ 249
           S P R +  P    PG PG    PS  E+R+S      G  Q A+
Sbjct: 361 SAPLRPSARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEAR 404


>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
            isoform 4 [Homo sapiens]
          Length = 2490

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)

Query: 89   DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR 131
            D R   GD VL +NG S +G TH QAVE +R  G  +HL++ +
Sbjct: 1414 DGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK 1456



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 94   VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVI-RRPLETHPGKPRGVGEPRKGVVP 152
            VGD++L +NG S +GL+  + +  +R   P++ L++ R P    P     +  P +    
Sbjct: 1555 VGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQ 1614

Query: 153  SWPDRSPDPGGPEVTGSRSSS 173
              P+ S D   P      +SS
Sbjct: 1615 VLPNSSKDSSQPSCVEQSTSS 1635



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 89   DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
            D R + GD ++ +N      +TH  AV  +RA    + LVI R LE
Sbjct: 1830 DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1875



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 27/126 (21%), Positives = 50/126 (39%), Gaps = 7/126 (5%)

Query: 75   IEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHL-VIRRPL 133
            + ++D        ++   Q+ D++ ++NG STQG+T  +    +    P L L   R  L
Sbjct: 1913 VYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDL 1972

Query: 134  ETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSST------SLVQHPPSRTTLK 187
               P   R      K    +          P +T + S ST      + + +P  + +  
Sbjct: 1973 PVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTY 2032

Query: 188  KTRGSP 193
            + +GSP
Sbjct: 2033 QIKGSP 2038



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 13/40 (32%), Positives = 24/40 (60%)

Query: 95   GDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
            GD ++ +N  S +G++H  A+E ++     + LVI +P E
Sbjct: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKE 1180


>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
            isoform 3 [Homo sapiens]
          Length = 2294

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)

Query: 89   DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR 131
            D R   GD VL +NG S +G TH QAVE +R  G  +HL++ +
Sbjct: 1218 DGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK 1260



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 94   VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVI-RRPLETHPGKPRGVGEPRKGVVP 152
            VGD++L +NG S +GL+  + +  +R   P++ L++ R P    P     +  P +    
Sbjct: 1359 VGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQ 1418

Query: 153  SWPDRSPDPGGPEVTGSRSSS 173
              P+ S D   P      +SS
Sbjct: 1419 VLPNSSKDSSQPSCVEQSTSS 1439



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 89   DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
            D R + GD ++ +N      +TH  AV  +RA    + LVI R LE
Sbjct: 1634 DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1679



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 27/126 (21%), Positives = 50/126 (39%), Gaps = 7/126 (5%)

Query: 75   IEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHL-VIRRPL 133
            + ++D        ++   Q+ D++ ++NG STQG+T  +    +    P L L   R  L
Sbjct: 1717 VYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDL 1776

Query: 134  ETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSST------SLVQHPPSRTTLK 187
               P   R      K    +          P +T + S ST      + + +P  + +  
Sbjct: 1777 PVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTY 1836

Query: 188  KTRGSP 193
            + +GSP
Sbjct: 1837 QIKGSP 1842



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 13/40 (32%), Positives = 24/40 (60%)

Query: 95  GDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
           GD ++ +N  S +G++H  A+E ++     + LVI +P E
Sbjct: 950 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKE 989


>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
            isoform 1 [Homo sapiens]
          Length = 2485

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)

Query: 89   DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR 131
            D R   GD VL +NG S +G TH QAVE +R  G  +HL++ +
Sbjct: 1409 DGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK 1451



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 94   VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVI-RRPLETHPGKPRGVGEPRKGVVP 152
            VGD++L +NG S +GL+  + +  +R   P++ L++ R P    P     +  P +    
Sbjct: 1550 VGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQ 1609

Query: 153  SWPDRSPDPGGPEVTGSRSSS 173
              P+ S D   P      +SS
Sbjct: 1610 VLPNSSKDSSQPSCVEQSTSS 1630



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 89   DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
            D R + GD ++ +N      +TH  AV  +RA    + LVI R LE
Sbjct: 1825 DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1870



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 27/126 (21%), Positives = 50/126 (39%), Gaps = 7/126 (5%)

Query: 75   IEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHL-VIRRPL 133
            + ++D        ++   Q+ D++ ++NG STQG+T  +    +    P L L   R  L
Sbjct: 1908 VYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDL 1967

Query: 134  ETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSST------SLVQHPPSRTTLK 187
               P   R      K    +          P +T + S ST      + + +P  + +  
Sbjct: 1968 PVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTY 2027

Query: 188  KTRGSP 193
            + +GSP
Sbjct: 2028 QIKGSP 2033



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 13/40 (32%), Positives = 24/40 (60%)

Query: 95   GDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
            GD ++ +N  S +G++H  A+E ++     + LVI +P E
Sbjct: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKE 1180


>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
            2 [Homo sapiens]
          Length = 2466

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%)

Query: 89   DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR 131
            D R   GD VL +NG S +G TH QAVE +R  G  +HL++ +
Sbjct: 1390 DGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK 1432



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 94   VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVI-RRPLETHPGKPRGVGEPRKGVVP 152
            VGD++L +NG S +GL+  + +  +R   P++ L++ R P    P     +  P +    
Sbjct: 1531 VGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQ 1590

Query: 153  SWPDRSPDPGGPEVTGSRSSS 173
              P+ S D   P      +SS
Sbjct: 1591 VLPNSSKDSSQPSCVEQSTSS 1611



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 89   DHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
            D R + GD ++ +N      +TH  AV  +RA    + LVI R LE
Sbjct: 1806 DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1851



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 27/126 (21%), Positives = 50/126 (39%), Gaps = 7/126 (5%)

Query: 75   IEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHL-VIRRPL 133
            + ++D        ++   Q+ D++ ++NG STQG+T  +    +    P L L   R  L
Sbjct: 1889 VYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDL 1948

Query: 134  ETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSST------SLVQHPPSRTTLK 187
               P   R      K    +          P +T + S ST      + + +P  + +  
Sbjct: 1949 PVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTY 2008

Query: 188  KTRGSP 193
            + +GSP
Sbjct: 2009 QIKGSP 2014



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 13/40 (32%), Positives = 24/40 (60%)

Query: 95   GDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLE 134
            GD ++ +N  S +G++H  A+E ++     + LVI +P E
Sbjct: 1122 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKE 1161


>gi|5803177 basic beta 2 syntrophin [Homo sapiens]
          Length = 540

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 49/179 (27%), Positives = 75/179 (41%), Gaps = 19/179 (10%)

Query: 3   PRTGGAANPKGSRGSRG---PSPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATL 59
           P  GGA +      SRG   PSP A P  R       A P   R  V V       G ++
Sbjct: 74  PNGGGAGDSLPGSPSRGLGPPSPPAPP--RGPAGEAGASPPVRRVRV-VKQEAGGLGISI 130

Query: 60  RLRRKEAVSVLDSADIEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIR 119
           +  R+  + +L S       +    A       ++GD +L +NG   +  TH QAV+ ++
Sbjct: 131 KGGRENRMPILISKIFPGLAADQSRAL------RLGDAILSVNGTDLRQATHDQAVQALK 184

Query: 120 AGGPQLHLVIR--RPLETHPGKPRGVGE-PRKGVVPSWPDRSPDPGGPEVTGSRSSSTS 175
             G ++ L ++  R +  +  KP  V + P +G  P    +SP   G E +GS     S
Sbjct: 185 RAGKEVLLEVKFIREVTPYIKKPSLVSDLPWEGAAP----QSPSFSGSEDSGSPKHQNS 239


>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
            sapiens]
          Length = 1309

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 67/254 (26%), Positives = 90/254 (35%), Gaps = 59/254 (23%)

Query: 16   GSRGP--SPLA------GPSARQLLARLDARPLAA--RAAVDVAALVRRAGATLRLRRKE 65
            GS GP  SPL+       PS+R      D  P+    R  + + +  ++ G +LR  R  
Sbjct: 911  GSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIR-- 968

Query: 66   AVSVLDSADIEVTDSRLPHATIVDHRP------QVGDLVLHINGESTQGLTHAQAVERIR 119
                +   D +V        ++ D  P      + GDL+ HINGES  GL H   VE + 
Sbjct: 969  ----VYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLL 1024

Query: 120  AGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSR--------- 170
              G ++ L     LE    K   VG  RK V      R         T  R         
Sbjct: 1025 KSGNKISL-RTTALENTSIK---VGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKIS 1080

Query: 171  --------------------SSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPE 210
                                SSS SL   P    +   T     P+P+  AD  T SPP 
Sbjct: 1081 KQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPAD-TTASPP- 1138

Query: 211  RRAEDPNDQIPGSP 224
              +  P+   P SP
Sbjct: 1139 --SASPSSSSPASP 1150



 Score = 32.7 bits (73), Expect = 0.32
 Identities = 51/231 (22%), Positives = 78/231 (33%), Gaps = 38/231 (16%)

Query: 20   PSPLAGPSARQLLARLDARPLAARAAVDVAALVRRAGATLRLRRK--EAVSV-LDSADIE 76
            P+  AG  A  L+  ++   +     +DV  L+ ++G  + LR    E  S+ +  A   
Sbjct: 991  PAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKN 1050

Query: 77   VTDSRLPHATIVDHRPQVGDL-------------VLHINGESTQGLTHAQAVERIRAGGP 123
            V   R+   +    R +  D              VLH +   + GL H+ +      G P
Sbjct: 1051 VAKGRMARRSKRSRRRETQDRRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSP 1110

Query: 124  QLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSR 183
                     L   P  P     P    VP+    SP    P  +   S + +    P S 
Sbjct: 1111 T------HSLSPSPTTPCRSPAPD---VPADTTASPPSASPSSSSPASPAAAGHTRPSSL 1161

Query: 184  TTLKKTRGSPEPS----------PEAAADGPTVSPPERRAEDPNDQIPGSP 224
              L    G P P           P +    P +S P  R+  P   +PG P
Sbjct: 1162 HGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPRSPSP---LPGHP 1209


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 70/268 (26%), Positives = 89/268 (33%), Gaps = 32/268 (11%)

Query: 7   GAANPKGSRGSRGPSPL--AGPSARQLLARLDARPLAARAAVDVAA-LVRRAGATLRLRR 63
           G + P+G   S  P  L  A PSA +++    A P +  A    A         +   RR
Sbjct: 150 GPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERR 209

Query: 64  KEAVSVLDSADIEVTDSRLPHATIVDHRPQVGDLVLHINGESTQGLTHAQAVERIRAGGP 123
             A   L  + +     R P       RP          G    G   A    R R G  
Sbjct: 210 ARAGPFLTPSPLHAVAMRSPRPC---GRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAG 266

Query: 124 QLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQ-HPPS 182
           Q          T PG   G    +  V    PD SP PG      +R  S   V  HP S
Sbjct: 267 QPR--------TSPGGADGGPRRQNSVRQRPPDASPSPGSARP--AREPSLERVGGHPTS 316

Query: 183 RTTLKK-------TRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGS-------PGPWL 228
              L +       +  +PEP+   AA  P  SP E R       IPG+       PG   
Sbjct: 317 PAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKA-QYIPGAQAATRGLPGRAA 375

Query: 229 VPSEERLSRALGVRGAAQLAQEMAAGRR 256
                 L+R   V  +    +  AAGRR
Sbjct: 376 RRKPPPLTRGRSVEQSPPRERPRAAGRR 403


>gi|4507137 acidic alpha 1 syntrophin [Homo sapiens]
          Length = 505

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 50/203 (24%), Positives = 78/203 (38%), Gaps = 21/203 (10%)

Query: 16  GSRGPSPLAGPSARQLLARLD--ARPLAARAAVDVAALVRRAGATLRLRRKEAVSVLDSA 73
           G  GP P  G    Q  A+L+  A P A    +  A L++R   T+R      + +    
Sbjct: 47  GDPGPEP--GAPREQEPAQLNGAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKG 104

Query: 74  DIE----VTDSRLPHATIVDHRPQ--VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHL 127
             E    +  S++      D      VGD +L +NGE     TH +AV+ ++  G ++ L
Sbjct: 105 GRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVL 164

Query: 128 VIRRPLETHPGKPRGVGEPRKGVVPSW--PDRSPDPGGPEVTGSRSSSTSLVQHPPSRTT 185
            ++   +  P      G    G    W  P  SP    P   G    + S  +H   +  
Sbjct: 165 EVKYMKDVSPYFKNSTG----GTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMA 220

Query: 186 LKKTRGSP-EPSPE----AAADG 203
               R +P +P P      +ADG
Sbjct: 221 YVSKRCTPNDPEPRYLEICSADG 243


>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
          Length = 222

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 26/64 (40%), Positives = 35/64 (54%), Gaps = 4/64 (6%)

Query: 94  VGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRR--PLETHPGKPR--GVGEPRKG 149
           VGD VL I+GE+   LTH +A  +IRA G +L L + R  P+++ P K        PR  
Sbjct: 46  VGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYT 105

Query: 150 VVPS 153
             PS
Sbjct: 106 FAPS 109


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 26/96 (27%), Positives = 31/96 (32%), Gaps = 4/96 (4%)

Query: 137 PGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPS 196
           P + RG   P     P+     P P  P V         +   PP         G P P 
Sbjct: 303 PARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPP 362

Query: 197 PEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSE 232
           P     GP   PP      P    PG P P  +PS+
Sbjct: 363 PSVLGVGPVAPPPPPPPPPP----PGPPPPPGLPSD 394


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,665,736
Number of Sequences: 37866
Number of extensions: 786086
Number of successful extensions: 6823
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 200
Number of HSP's successfully gapped in prelim test: 513
Number of HSP's that attempted gapping in prelim test: 4665
Number of HSP's gapped (non-prelim): 2647
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.