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Search of human proteins with 150456460
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
(1008 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 2061 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 1078 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 934 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 926 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 923 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 896 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 870 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 869 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 822 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 813 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 810 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 803 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 760 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 731 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 701 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 671 0.0
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 591 e-168
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 521 e-147
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 424 e-118
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 202 2e-51
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 202 2e-51
gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isofo... 187 3e-47
gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isofo... 187 3e-47
gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like... 186 7e-47
gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isofo... 184 3e-46
gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isofor... 184 3e-46
gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isofo... 184 3e-46
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 183 6e-46
gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens] 182 1e-45
gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens] 182 1e-45
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 2061 bits (5340), Expect = 0.0
Identities = 1008/1008 (100%), Positives = 1008/1008 (100%)
Query: 1 METCAGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEE 60
METCAGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEE
Sbjct: 1 METCAGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEE 60
Query: 61 ISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAG 120
ISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAG
Sbjct: 61 ISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAG 120
Query: 121 TCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREI 180
TCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREI
Sbjct: 121 TCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREI 180
Query: 181 GPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTC 240
GPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTC
Sbjct: 181 GPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTC 240
Query: 241 VAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCS 300
VAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCS
Sbjct: 241 VAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCS 300
Query: 301 PCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWL 360
PCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWL
Sbjct: 301 PCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWL 360
Query: 361 PPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGAR 420
PPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGAR
Sbjct: 361 PPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGAR 420
Query: 421 YTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPA 480
YTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPA
Sbjct: 421 YTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPA 480
Query: 481 GAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEA 540
GAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEA
Sbjct: 481 GAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEA 540
Query: 541 QSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGG 600
QSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGG
Sbjct: 541 QSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGG 600
Query: 601 DAHDEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELC 660
DAHDEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELC
Sbjct: 601 DAHDEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELC 660
Query: 661 CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLM 720
CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLM
Sbjct: 661 CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLM 720
Query: 721 IVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSS 780
IVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSS
Sbjct: 721 IVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSS 780
Query: 781 DLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVM 840
DLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVM
Sbjct: 781 DLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVM 840
Query: 841 AFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL 900
AFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
Sbjct: 841 AFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL 900
Query: 901 SKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYG 960
SKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYG
Sbjct: 901 SKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYG 960
Query: 961 SLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQLQGQGVQV 1008
SLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQLQGQGVQV
Sbjct: 961 SLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQLQGQGVQV 1008
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 1078 bits (2787), Expect = 0.0
Identities = 531/985 (53%), Positives = 707/985 (71%), Gaps = 25/985 (2%)
Query: 33 AEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGW 92
A+EV+LLDSKA Q EL W + P NGWEEISG+DE+ PIRTYQVC V+EPNQ+NWL+T W
Sbjct: 30 AKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNW 89
Query: 93 ISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKI 152
IS+G QRIFVEL+FTLRDC+S+PG GTCKETFN+YY ET+ D GR + + KI
Sbjct: 90 ISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRN---IRENLYVKI 146
Query: 153 DTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCR 212
DTIAADESFTQGDLGERKMKLNTEVREIGPLS++GF+LAFQDVGAC+ALVSV+VYYK+C
Sbjct: 147 DTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCW 206
Query: 213 ATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCS 272
+ + LA FP T S FS+LVEV GTCV+ +E E + PRMHC A+GEWLVP+G+C C
Sbjct: 207 SIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICK 266
Query: 273 AGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSA 332
AG+Q++GD CE C GFYK S + CS CP HS + + S+ C C+D Y R+P+DPP
Sbjct: 267 AGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYV 326
Query: 333 SCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPC 392
+CTRPPSAP++L ++++++ + L W PPAD+GGR+DVTY +LC RC E G C PC
Sbjct: 327 ACTRPPSAPQNLIFNINQT--TVSLEWSPPADNGGRNDVTYRILCKRCSWE--QGECVPC 382
Query: 393 GPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPG 452
G + ++P+Q GL + T++ L A YT V A+NGVS + + +A V+++TG
Sbjct: 383 GSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVS-DLSRSQRLFAAVSITTGQA 441
Query: 453 APWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAP 512
AP + + ++RV +SV LSW+EP P TEYEI+YYEK Q E+TYS VKT +
Sbjct: 442 APSQVSGVMKERVLQRSVELSWQEP---EHPNGVITEYEIKYYEKDQRERTYSTVKTKST 498
Query: 513 TVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLG-------EAASGSRDQSPA 565
+ ++ NLKP T YVFQIRA + +++P ++V TL EA + S +Q+P
Sbjct: 499 SASINNLKPGTVYVFQIRAFTAA---GYGNYSPRLDVATLEEATGKMFEATAVSSEQNPV 555
Query: 566 IVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFHFKVPTRRTFLDPQS 625
I++ VV ++ ++L ++ I RR C Y K D +EELYFHFK P +T++DP++
Sbjct: 556 IIIAVVAVAGTIILVFMVFGFIIGRRHCGYSK--ADQEGDEELYFHFKFPGTKTYIDPET 613
Query: 626 CGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASD 685
D +AVH FAKELDA + +ER +G G FGE+C G L+LPG++++ VA+ L+ ++
Sbjct: 614 YEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTE 673
Query: 686 SQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAG 745
QR FL EA +GQFDH ++V LEGVVTRG +MIV E+M +GALD FLR+H+GQ
Sbjct: 674 KQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVI 733
Query: 746 QLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTT 803
QL+G+L G+A+ M+YL++MGYVHR LAAR++LV+S+LVCK+S FG R D EAVYTT
Sbjct: 734 QLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTT 793
Query: 804 MSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGF 863
G+ P W APE +Q+ F+SASDVWS+GI+MWEVM++GERPYWDMS QDVIKA+E+G+
Sbjct: 794 TGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 853
Query: 864 RLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTP 923
RLP P +CP LH+LMLDCWQK+ ERP+F QI IL KM+++P K L TC RP +P
Sbjct: 854 RLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISP 913
Query: 924 LADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEH 983
L D+ F +F SVG WL+A+ + RYKD+F AAGY SLE+VA MT +D++SLGI+L H
Sbjct: 914 LLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGH 973
Query: 984 REALLSGISALQARVLQLQGQGVQV 1008
++ ++S I ++A++L L G G+QV
Sbjct: 974 QKKIMSSIQTMRAQMLHLHGTGIQV 998
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 934 bits (2414), Expect = 0.0
Identities = 478/1000 (47%), Positives = 665/1000 (66%), Gaps = 28/1000 (2%)
Query: 5 AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGV 64
+ P L+ C + LC AL P + EV LLDS+ +LGW A P NGWEEI V
Sbjct: 33 SAPRRAPLWTCLL-LCAALRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEV 89
Query: 65 DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124
DE+ PI TYQVC V+E NQ+NWL T WIS RIF+EL+FTLRDC+S+PG GTCKE
Sbjct: 90 DENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKE 149
Query: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184
TFN+YY E++ GR + ++ KIDTIAADESFT+ DLG+R MKLNTEVR++GPLS
Sbjct: 150 TFNMYYFESDDQNGRN---IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLS 206
Query: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244
++GF+LAFQDVGAC+ALVSVRVYYK+C + VR LA FP T + S L+EV+G+CV HS
Sbjct: 207 KKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS 266
Query: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPE 304
+ PP+MHC A+GEWLVP+G+C C AG++E+ C+ C PGF+K SP C CP
Sbjct: 267 VTD--EPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPP 324
Query: 305 HSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPAD 364
HS E AST CVC+ Y R +DPP+ +CTRPPSAPR+ +++ + + L W+PPAD
Sbjct: 325 HSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLE--WIPPAD 382
Query: 365 SGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVR 424
+GGR DV+Y + C +C AG CE CG V +LPRQ+GL+ + ++ L YT
Sbjct: 383 TGGRKDVSYYIACKKCNSH--AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFE 440
Query: 425 VAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPG 484
+ A+NGVS + A Y V V+T AP +++ ++ S+SLSW+EP P
Sbjct: 441 IEAVNGVSDLSPGA-RQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEP---DRPN 496
Query: 485 ANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFN 544
EYEI+Y+EK Q E +Y+++K+ T+T LKPA+ YVFQIRA + F+
Sbjct: 497 GIILEYEIKYFEKDQ-ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGV---FS 552
Query: 545 PSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHD 604
E +T A+ S DQS V+ V +++L V+ VL RR C Y K D +
Sbjct: 553 RRFEFETTPVFAASS-DQSQIPVIAVSVTVGVILLAVVIGVLLSGRR-CGYSKAKQDP-E 609
Query: 605 EEELYFH---FKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCC 661
EE+++FH K+P RT++DP + D QAVH FAKE++A +T+ER +G G FGE+C
Sbjct: 610 EEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCS 669
Query: 662 GCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMI 721
G L+LPG++EL VA+ L+ ++ QR FL EA +GQFDH +I+ LEGVVT+ +MI
Sbjct: 670 GRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMI 729
Query: 722 VTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSD 781
VTEYM +G+LD FL++++GQ QL+G+L G+++ MKYLS+MGYVHR LAAR++L++S+
Sbjct: 730 VTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSN 789
Query: 782 LVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEV 839
LVCK+S FG R D EA YTT G+ P W APE + F F+SASDVWS+GI+MWEV
Sbjct: 790 LVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEV 849
Query: 840 MAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSI 899
+++GERPYW+M+ QDVIKAVE+G+RLP P +CP L++LMLDCWQK+ RP+F +I ++
Sbjct: 850 VSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNM 909
Query: 900 LSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGY 959
L K++++P K + R LA+ + ++ SVG WLEA+ + RY + F GY
Sbjct: 910 LDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGY 969
Query: 960 GSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVL 999
S++AVA++T +DL LG++L H++ +++ + ++ +++
Sbjct: 970 SSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLV 1009
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 926 bits (2394), Expect = 0.0
Identities = 481/1022 (47%), Positives = 668/1022 (65%), Gaps = 50/1022 (4%)
Query: 5 AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGV 64
+ P L+ C + LC AL P + EV LLDS+ +LGW A P NGWEEI V
Sbjct: 33 SAPRRAPLWTCLL-LCAALRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEV 89
Query: 65 DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124
DE+ PI TYQVC V+E NQ+NWL T WIS RIF+EL+FTLRDC+S+PG GTCKE
Sbjct: 90 DENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKE 149
Query: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184
TFN+YY E++ GR + ++ KIDTIAADESFT+ DLG+R MKLNTEVR++GPLS
Sbjct: 150 TFNMYYFESDDQNGRN---IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLS 206
Query: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244
++GF+LAFQDVGAC+ALVSVRVYYK+C + VR LA FP T + S L+EV+G+CV HS
Sbjct: 207 KKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS 266
Query: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPE 304
+ PP+MHC A+GEWLVP+G+C C AG++E+ C+ C PGF+K SP C CP
Sbjct: 267 VTD--EPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPP 324
Query: 305 HSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPAD 364
HS E AST CVC+ Y R +DPP+ +CTRPPSAPR+ +++ + + L W+PPAD
Sbjct: 325 HSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLE--WIPPAD 382
Query: 365 SGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVR 424
+GGR DV+Y + C +C AG CE CG V +LPRQ+GL+ + ++ L YT
Sbjct: 383 TGGRKDVSYYIACKKCNSH--AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFE 440
Query: 425 VAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPG 484
+ A+NGVS + A Y V V+T AP +++ ++ S+SLSW+EP P
Sbjct: 441 IEAVNGVSDLSPGA-RQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEP---DRPN 496
Query: 485 ANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFN 544
EYEI+Y+EK Q E +Y+++K+ T+T LKPA+ YVFQIRA + F+
Sbjct: 497 GIILEYEIKYFEKDQ-ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGV---FS 552
Query: 545 PSIEVQTLGE-AASGSRDQSP--AIVVTVVTISALLVLGSVMSVLA-------------- 587
E +T AAS + Q P A+ VTV I +V+G ++S
Sbjct: 553 RRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAV 612
Query: 588 -----IWRRPCSYGKGGGDAHDEEELYFH---FKVPTRRTFLDPQSCGDLLQAVHLFAKE 639
IWR C Y K D +EE+++FH K+P RT++DP + D QAVH FAKE
Sbjct: 613 AHPSLIWR--CGYSKAKQDP-EEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKE 669
Query: 640 LDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLG 699
++A +T+ER +G G FGE+C G L+LPG++EL VA+ L+ ++ QR FL EA +G
Sbjct: 670 IEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMG 729
Query: 700 QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMK 759
QFDH +I+ LEGVVT+ +MIVTEYM +G+LD FL++++GQ QL+G+L G+++ MK
Sbjct: 730 QFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMK 789
Query: 760 YLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPET 817
YLS+MGYVHR LAAR++L++S+LVCK+S FG R D EA YTT G+ P W APE
Sbjct: 790 YLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEA 849
Query: 818 LQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHR 877
+ F F+SASDVWS+GI+MWEV+++GERPYW+M+ QDVIKAVE+G+RLP P +CP L++
Sbjct: 850 IAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQ 909
Query: 878 LMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGS 937
LMLDCWQK+ RP+F +I ++L K++++P K + R LA+ + ++ S
Sbjct: 910 LMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRS 969
Query: 938 VGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQAR 997
VG WLEA+ + RY + F GY S++AVA++T +DL LG++L H++ +++ + ++ +
Sbjct: 970 VGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQ 1029
Query: 998 VL 999
++
Sbjct: 1030 LV 1031
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 923 bits (2386), Expect = 0.0
Identities = 471/994 (47%), Positives = 663/994 (66%), Gaps = 36/994 (3%)
Query: 18 QLCLALLL--------GPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDR 69
QL + LLL G P + EV LLDSK Q ELGW + PS+GWEEISGVDEH
Sbjct: 4 QLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYT 63
Query: 70 PIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVY 129
PIRTYQVCNV++ +Q+NWL+T W+ R Q+I+VEL+FTLRDC+SIP GTCKETFN+Y
Sbjct: 64 PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLY 123
Query: 130 YLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFH 189
Y+E++ D G + + KIDTIAADESFTQ DLG+R +KLNTE+RE+GP++++GF+
Sbjct: 124 YMESDDDHG---VKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Query: 190 LAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPG 249
LAFQDVGACVALVSVRVY+K+C TV+ LA FP T + S LVEV G+CV +S+ E
Sbjct: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQS-LVEVRGSCVNNSKEE-- 237
Query: 250 SPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRAL 309
PPRM+C +GEWLVP+G+CSC+AG++ERG C+AC PGFYK C+ CP HS
Sbjct: 238 DPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQ 297
Query: 310 ENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRS 369
E+ S C C+++Y R+ DPPS +CTRPPS+PR++ +++ + ++L W P D+GGR
Sbjct: 298 EDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSW--PLDTGGRK 355
Query: 370 DVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALN 429
DVT++++C +CG CEPC P V FLPRQ GL T+ L YT + A+N
Sbjct: 356 DVTFNIICKKCGWN--IKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
Query: 430 GVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTE 489
GVS ++ +A V+++T AP I++DR S+SLSW+EP P +
Sbjct: 414 GVS-ELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEP---EHPNGIILD 469
Query: 490 YEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRA-ASPGPSWEAQSFNPSIE 548
YE++YYEK + E +Y++++ VT+++LKP T YVFQIRA + G ++ F E
Sbjct: 470 YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKF----E 525
Query: 549 VQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEEL 608
+T ++ S S + S +++ + A+++L V+ VL R C Y G DE+ L
Sbjct: 526 FETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVLI--GRFCGYKSKHGA--DEKRL 581
Query: 609 YF---HFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQ 665
+F H K+P RT++DP + D QAVH FAKELDA ++++++ +G G FGE+C G L+
Sbjct: 582 HFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLK 641
Query: 666 LPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEY 725
LP ++E+ VA+ L+ ++ QR FL EA +GQFDH +I+RLEGVVT+ +MIVTEY
Sbjct: 642 LPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEY 701
Query: 726 MSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCK 785
M +G+LD FLR+H+ Q QL+G+L G+AS MKYLS+MGYVHR LAAR++L++S+LVCK
Sbjct: 702 MENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCK 761
Query: 786 ISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFG 843
+S FG R D EA YTT G+ P W +PE + + F+SASDVWS+GI++WEVM++G
Sbjct: 762 VSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYG 821
Query: 844 ERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKM 903
ERPYW+MS QDVIKAV++G+RLPPP +CP L++LMLDCWQKD RP+F QI SIL K+
Sbjct: 822 ERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
Query: 904 VQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLE 963
+++P K + RP L D++ +F + G WL + K+ F Y S +
Sbjct: 882 IRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCD 941
Query: 964 AVAEMTAQDLVSLGISLAEHREALLSGISALQAR 997
+A+++ D+ +G+++ ++ ++S I AL+ +
Sbjct: 942 TIAKISTDDMKKVGVTVVGPQKKIISSIKALETQ 975
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 896 bits (2316), Expect = 0.0
Identities = 464/1007 (46%), Positives = 656/1007 (65%), Gaps = 25/1007 (2%)
Query: 5 AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALP-SNGWEEISG 63
AG LF C +C A+ P A EV LLDS++ Q ELGW A P GWEE+S
Sbjct: 2 AGIFYFALFSCLFGICDAVTGSRVYP--ANEVTLLDSRSVQGELGWIASPLEGGWEEVSI 59
Query: 64 VDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCK 123
+DE + PIRTYQVCNV+EP+Q+NWL+T WI+R QR+++E++FTLRDC+S+PG GTCK
Sbjct: 60 MDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCK 119
Query: 124 ETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPL 183
ETFN+YY E++ D R + ++ KIDTIAADESFTQ D+G+R MKLNTE+R++GPL
Sbjct: 120 ETFNLYYYESDNDKERF---IRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPL 176
Query: 184 SRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAH 243
S++GF+LAFQDVGAC+ALVSVRV+YK+C TVR LA FP T + S+LVEV G+CV +
Sbjct: 177 SKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNN 236
Query: 244 SEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCP 303
SE + P+M+CGADGEWLVP+G C C+AG +ER C+AC G+YK C+ CP
Sbjct: 237 SEEK--DVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCP 294
Query: 304 EHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPA 363
HS ++ +T C C + R+ D S CTRPPSAP +L +++ + + L W P
Sbjct: 295 PHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSV--NLEWSSPQ 352
Query: 364 DSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTV 423
++GGR D++Y+++C +CG P+ C PCG V + P+Q GL+ ++ L YT
Sbjct: 353 NTGGRQDISYNVVCKKCGAGDPS-KCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTF 411
Query: 424 RVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAP 483
+ A+NGVS + + VTV+T AP ++ V SV+L+W EP P
Sbjct: 412 EIWAVNGVSKYNPNPDQSVS-VTVTTNQAAPSSIALVQAKEVTRYSVALAWLEP---DRP 467
Query: 484 GANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSF 543
EYE++YYEK Q+E++Y +V+T A + L P T YVF +RA + + F
Sbjct: 468 NGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGD---F 524
Query: 544 NPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAH 603
+ +EV T + D + + V+ V +++++ +++ I RR Y K +A
Sbjct: 525 SEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEAD 584
Query: 604 DEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGC 663
+E+ L RT++DP + D QAV FAKE+DA + +E+ +G G FGE+C G
Sbjct: 585 EEKHLNQGV-----RTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGR 639
Query: 664 LQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVT 723
L++PG++E+ VA+ L+ +D QR FL+EA +GQFDH +I+ LEGVVT+ +MI+T
Sbjct: 640 LKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIIT 699
Query: 724 EYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLV 783
EYM +G+LD FLR+++G+ QL+G+L G+ S MKYLS+M YVHR LAAR++LV+S+LV
Sbjct: 700 EYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLV 759
Query: 784 CKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMA 841
CK+S FG R D EA YTT G+ P W APE + + F+SASDVWS+GI+MWEVM+
Sbjct: 760 CKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
Query: 842 FGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILS 901
+GERPYWDMS QDVIKA+E+G+RLPPP +CP LH+LMLDCWQK+ +RP+F QI ++L
Sbjct: 820 YGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879
Query: 902 KMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGS 961
K++++P K T RP T L D + F + SVG WL+A+ + RYKD+F AAGY +
Sbjct: 880 KLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTT 939
Query: 962 LEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQLQGQGVQV 1008
LEAV + +DL +GI+ H+ +LS + A++ ++ Q+ G+ V V
Sbjct: 940 LEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV 986
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 870 bits (2248), Expect = 0.0
Identities = 457/1055 (43%), Positives = 645/1055 (61%), Gaps = 80/1055 (7%)
Query: 10 LRLFLCRMQLCLALLLGPWRPGTAE-----EVILLDSKASQAELGWTALPSNGWEEISGV 64
+R FL + L LL W PG +V+LLD+ ELGW P NGW+ I+ +
Sbjct: 100 VREFLLQFGFFLPLLTA-W-PGDCSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEM 157
Query: 65 DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124
DEH+RPI TYQVCNV+EPNQ+NWL+T WISR Q+I+VE++FTLRDC+SIP GTCKE
Sbjct: 158 DEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKE 217
Query: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184
TFN++Y+E++ G + ++ KIDTIAADESFTQ DLG+R +KLNTE+RE+GP+
Sbjct: 218 TFNLFYMESDESHG---IKFKPNQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIE 274
Query: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244
R+GF+LAFQD+GAC+ALVSVRV+YK+C TVR LA FP T S+LVEV G+CV
Sbjct: 275 RKGFYLAFQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCV--K 332
Query: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPE 304
E P+++CGADG+WLVP+GRC CS G++E C AC PGFYK CS CP
Sbjct: 333 SAEERDTPKLYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPP 392
Query: 305 HSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPAD 364
HS A++ C C+ Y R+ DPPS +CTRPPSAPR++ ++++ + L+ L W PP+D
Sbjct: 393 HSLTYMEATSVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALI--LEWSPPSD 450
Query: 365 SGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVR 424
+GGR D+TYS++C +CG + CE CG + F+PR GL + +L YT
Sbjct: 451 TGGRKDLTYSVICKKCGLD--TSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFE 508
Query: 425 VAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPG 484
+ A+NGVS + + + +TV+T AP +R+D S++LSW+ PA + G
Sbjct: 509 IEAMNGVS-ELSFSPKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQ--APAFSNG 565
Query: 485 ANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRA-ASPGPSWEAQSF 543
A +YEI+YYEK + TYS ++ AP+V +T LKPAT+YVF IR + G S +Q F
Sbjct: 566 A-ILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKF 624
Query: 544 NPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAH 603
E +T E + + +Q +V+ + +L + I R Y K +
Sbjct: 625 ----EFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSE 680
Query: 604 DEEELYF---HFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELC 660
++ + H + P +T++DP + D AVH FAKE+D + +ER +G G FGE+C
Sbjct: 681 EKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVC 740
Query: 661 CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTR----- 715
G L+ PG++E+ VA+ L+ D QR FL EA +GQFDH +I+RLEGVVT+
Sbjct: 741 SGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 800
Query: 716 -------------------------------------GSTLMIVTEYMSHGALDGFLRRH 738
G +MIV EYM +G+LD FLR+H
Sbjct: 801 IGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 860
Query: 739 EGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPRDR 796
+G QL+G+L G+AS MKYLS+MGYVHR LAAR++LV+S+LVCK+S FG R D
Sbjct: 861 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDD 920
Query: 797 SEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVI 856
EA YTT G+ P W APE + + FSSASD WS+GI+MWEVM++GERPYW+MS QDVI
Sbjct: 921 PEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVI 980
Query: 857 KAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCA--- 913
++E+G+RLP P CP LH+LML CWQK+ RP+F+ I S L K++++P
Sbjct: 981 LSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVED 1040
Query: 914 LTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDL 973
+ P P + + +P F +VG WL+++ + +YK++F AAG+ + + ++ M+ D+
Sbjct: 1041 ILVMPESPGEVPE-----YPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDI 1095
Query: 974 VSLGISLAEHREALLSGISALQARVLQLQGQGVQV 1008
+G+ L H+ ++S I L+ ++ +Q +G V
Sbjct: 1096 RRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV 1130
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
Length = 1005
Score = 869 bits (2246), Expect = 0.0
Identities = 454/994 (45%), Positives = 631/994 (63%), Gaps = 49/994 (4%)
Query: 35 EVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWIS 94
EV LLD+ + GW P++GW+ I+ VDE +PI TYQVCNV+ PNQ+NWL+T W+
Sbjct: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
Query: 95 RGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDT 154
R +R++ E++FTLRDC+S+PG GTCKETFN+YYLE++ DLG S+ KIDT
Sbjct: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQE---SQFLKIDT 147
Query: 155 IAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRAT 214
IAADESFT DLG R++KLNTEVR +GPLS+RGF+LAFQD+GAC+A++S+R+YYK+C A
Sbjct: 148 IAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAM 207
Query: 215 VRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAG 274
VR LA F + S+LVEV G CV HSE P+M+C A+GEWLVP+G+C CSAG
Sbjct: 208 VRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIGKCVCSAG 265
Query: 275 FQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASC 334
++ER D C AC GFYK +P LC+ CP HS + A+ C C SY R+ DPPS++C
Sbjct: 266 YEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSAC 325
Query: 335 TRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGP 394
TRPPSAP +L S++ + + L W PP D GGRSD+TY+ +C RC CE CG
Sbjct: 326 TRPPSAPVNLISSVNGTSVTLE--WAPPLDPGGRSDITYNAVCRRC--PWALSRCEACGS 381
Query: 395 RVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAP 454
F+P+Q L + + + +L Y+ + A+NGVS + A V ++T AP
Sbjct: 382 GTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRA-AVVNITTNQAAP 440
Query: 455 WEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTV 514
+ IR++R SVSL W+EP P EYEI+YYEK + Q+YS +K
Sbjct: 441 SQVVVIRQERAGQTSVSLLWQEP---EQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRA 497
Query: 515 TVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTIS 574
TV+ LKP TRYVFQ+RA + S F+ ++EV+T + + T+V I
Sbjct: 498 TVSGLKPGTRYVFQVRART---SAGCGRFSQAMEVET-------GKPRPRYDTRTIVWIC 547
Query: 575 ALLVLGSVMSVLAIW--RRPCSYGKGGGDAHDEEELYFHF----------------KVPT 616
L+ G V+ +L + +R C Y K D+ DEE++++ K+P
Sbjct: 548 LTLITGLVVLLLLLICKKRHCGYSKAFQDS-DEEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
Query: 617 RRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAV 676
+ + +P + + +A F +E++A + +E+ +G G GE+C G L++PG++++ VA+
Sbjct: 607 PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
Query: 677 HMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLR 736
L+ ++ QR FL+EA +GQFDH +I+RLEGVVTRG MIVTEYM +G+LD FLR
Sbjct: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
Query: 737 RHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPR 794
H+GQ QL+G+L G+ + M+YLS++GYVHR LAAR+VLV S+LVCK+S FG R
Sbjct: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
Query: 795 DRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQD 854
D +A YTT G+ P W APE + F FSSASDVWSFG++MWEV+A+GERPYW+M+ +D
Sbjct: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
Query: 855 VIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCAL 914
VI +VE+G+RLP P CP+ LH+LMLDCW KD +RPRFSQI S+L +++ PE +
Sbjct: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
Query: 915 TTCPRPPTPLADRAFSTFPSFG-----SVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMT 969
T PP F G +VG WL+++ + RY+D FAA GY SL V M
Sbjct: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
Query: 970 AQDLVSLGISLAEHREALLSGISALQARVLQLQG 1003
AQD+ +LGI+L H++ +L I ++A++ QG
Sbjct: 967 AQDVRALGITLMGHQKKILGSIQTMRAQLTSTQG 1000
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 822 bits (2124), Expect = 0.0
Identities = 424/976 (43%), Positives = 618/976 (63%), Gaps = 22/976 (2%)
Query: 33 AEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGW 92
A E L+D++ + AELGWTA P++GWEE+SG DE+ IRTYQVCNV EPNQ+NWL T +
Sbjct: 17 AMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTF 76
Query: 93 ISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPR-K 151
I+R RI+ E++FT+RDCSS+P G+CKETFN+YY ET++ + + P K
Sbjct: 77 INRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLK 136
Query: 152 IDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQC 211
+DTIAADESF+Q D G R MK+NTEVR GPL+R GF+LAFQD GAC++L+SVRV++K+C
Sbjct: 137 VDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKC 196
Query: 212 RATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSC 271
+ V+ A FP T + ++LV GTC+ ++E E P +++C DGEW+VP+GRC+C
Sbjct: 197 PSIVQNFAVFPETMTGAESTSLVIARGTCIPNAE-EVDVPIKLYCNGDGEWMVPIGRCTC 255
Query: 272 SAGFQ-ERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPP 330
G++ E C+ACP G +K S CS CP +SR+ AS C C+ Y R+ DPP
Sbjct: 256 KPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPP 315
Query: 331 SASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACE 390
+CT PS PR++ ++ + ++L W PP ++GGR DVTY+++C +C + +C
Sbjct: 316 EVACTSVPSGPRNVISIVNETSIILE--WHPPRETGGRDDVTYNIICKKCRAD--RRSCS 371
Query: 391 PCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTG 450
C V F+PRQ GL E ++ L YT + A+NGVS + + V ++T
Sbjct: 372 RCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFP-PQHVSVNITTN 430
Query: 451 PGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTG 510
AP + + +S++LSW +P P +YEIRYYEK +E SM ++
Sbjct: 431 QAAPSTVPIMHQVSATMRSITLSWPQP---EQPNGIILDYEIRYYEKEHNEFNSSMARSQ 487
Query: 511 APTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTL--GEAASGSRDQSPAIVV 568
T + L+P YV Q+RA + + F+ + QTL + S R+Q P I
Sbjct: 488 TNTARIDGLRPGMVYVVQVRARTVAGYGK---FSGKMCFQTLTDDDYKSELREQLPLIAG 544
Query: 569 TVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFHFKVPTRRTFLDPQSCGD 628
+ + ++ + S++++ + R +Y K + + P + ++DP + D
Sbjct: 545 SAA--AGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYED 602
Query: 629 LLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQR 688
+AV FAKE+D V +E +G G FGE+ G L+LPG++E+ VA+ L+ S+ QR
Sbjct: 603 PNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQR 662
Query: 689 LGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLM 748
FL+EA +GQFDH +I+RLEGVVT+ +MI+TE+M +GALD FLR+++GQ QL+
Sbjct: 663 RDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLV 722
Query: 749 GLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRG---PRDRSEAVYTT-M 804
G+L G+A+ MKYL+EM YVHR LAAR++LV+S+LVCK+S FG D S+ YT+ +
Sbjct: 723 GMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSL 782
Query: 805 SGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFR 864
G+ P W APE + + F+SASDVWS+GI+MWEVM+FGERPYWDMS QDVI A+E +R
Sbjct: 783 GGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYR 842
Query: 865 LPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTPL 924
LPPP +CP LH+LMLDCWQKD RPRF++I + L KM+++P K T P PL
Sbjct: 843 LPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPL 902
Query: 925 ADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHR 984
DR+ F +F +V WL A+ + +Y+DSF AG+ SL+ V +MT++DL+ +GI+LA H+
Sbjct: 903 LDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQ 962
Query: 985 EALLSGISALQARVLQ 1000
+ +L+ I +++ ++ Q
Sbjct: 963 KKILNSIHSMRVQISQ 978
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapiens]
Length = 987
Score = 813 bits (2101), Expect = 0.0
Identities = 423/993 (42%), Positives = 621/993 (62%), Gaps = 22/993 (2%)
Query: 18 QLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVC 77
+L ALLL P A E L+DS + AELGW P +GWEE+SG DE+ IRTYQVC
Sbjct: 5 RLGAALLLLPLL--AAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVC 62
Query: 78 NVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADL 137
NV E +Q+NWL+T +I R RI VE++F++RDCSSIP G+CKETFN+YY E + D
Sbjct: 63 NVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDS 122
Query: 138 G-RGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVG 196
+ P + K+DTIAADESF+Q DLG R MK+NTEVR GP+SR GF+LAFQD G
Sbjct: 123 ATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYG 182
Query: 197 ACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHC 256
C++L++VRV+Y++C ++ A F T + + ++LV G+C+A++E E P +++C
Sbjct: 183 GCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAE-EVDVPIKLYC 241
Query: 257 GADGEWLVPVGRCSCSAGFQ--ERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENAST 314
DGEWLVP+GRC C AGF+ E G C CP G +K + C+ CP +SR +T
Sbjct: 242 NGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGAT 301
Query: 315 FCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYS 374
CVC++ Y R+ DP CT PSAP+ + S++ + L+L W PP DSGGR D+ Y+
Sbjct: 302 NCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLE--WTPPRDSGGREDLVYN 359
Query: 375 LLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGP 434
++C CG GAC CG V + PRQ GL E + L +YT + A+NGV+
Sbjct: 360 IICKSCG--SGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQ 417
Query: 435 AAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRY 494
+ + +A V ++T AP + + S++LSW +P P +YE++Y
Sbjct: 418 SPFS-PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQP---DQPNGVILDYELQY 473
Query: 495 YEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGE 554
YEK SE + +K+ TVTV LK YVFQ+RA + ++ + QT+ E
Sbjct: 474 YEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGR---YSGKMYFQTMTE 530
Query: 555 AASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFH-FK 613
A + Q ++ + + L+ L +V+ + + R + + + D+ + Y
Sbjct: 531 AEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHM 590
Query: 614 VPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELL 673
P + ++DP + D +AV FAKE+D V +E+ +G G FGE+C G L+LPG++E+
Sbjct: 591 TPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIF 650
Query: 674 VAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDG 733
VA+ L+ ++ QR FL+EA +GQFDH +++ LEGVVT+ + +MI+TE+M +G+LD
Sbjct: 651 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 710
Query: 734 FLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRG- 792
FLR+++GQ QL+G+L G+A+ MKYL++M YVHR LAAR++LV+S+LVCK+S FG
Sbjct: 711 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSR 770
Query: 793 --PRDRSEAVYTT-MSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWD 849
D S+ YT+ + G+ P W APE +Q+ F+SASDVWS+GI+MWEVM++GERPYWD
Sbjct: 771 FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 830
Query: 850 MSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEP 909
M+ QDVI A+E +RLPPP +CP+ LH+LMLDCWQKD RP+F QI + L KM+++P
Sbjct: 831 MTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNS 890
Query: 910 PKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMT 969
K PL DR + SF +V WLEA+ + +YK+SFA AG+ S + V++M
Sbjct: 891 LKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMM 950
Query: 970 AQDLVSLGISLAEHREALLSGISALQARVLQLQ 1002
+D++ +G++LA H++ +L+ I ++A++ Q+Q
Sbjct: 951 MEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQ 983
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sapiens]
Length = 986
Score = 810 bits (2092), Expect = 0.0
Identities = 423/993 (42%), Positives = 621/993 (62%), Gaps = 23/993 (2%)
Query: 18 QLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVC 77
+L ALLL P A E L+DS + AELGW P +GWEE+SG DE+ IRTYQVC
Sbjct: 5 RLGAALLLLPLL--AAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVC 62
Query: 78 NVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADL 137
NV E +Q+NWL+T +I R RI VE++F++RDCSSIP G+CKETFN+YY E + D
Sbjct: 63 NVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDS 122
Query: 138 G-RGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVG 196
+ P + K+DTIAADESF+Q DLG R MK+NTEVR GP+SR GF+LAFQD G
Sbjct: 123 ATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYG 182
Query: 197 ACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHC 256
C++L++VRV+Y++C ++ A F T + + ++LV G+C+A++E E P +++C
Sbjct: 183 GCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAE-EVDVPIKLYC 241
Query: 257 GADGEWLVPVGRCSCSAGFQ--ERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENAST 314
DGEWLVP+GRC C AGF+ E G C CP G +K + C+ CP +SR +T
Sbjct: 242 NGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGAT 301
Query: 315 FCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYS 374
CVC++ Y R+ DP CT PSAP+ + S++ + L+L W PP DSGGR D+ Y+
Sbjct: 302 NCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLE--WTPPRDSGGREDLVYN 359
Query: 375 LLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGP 434
++C CG GAC CG V + PRQ GL E + L +YT + A+NGV+
Sbjct: 360 IICKSCG--SGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQ 417
Query: 435 AAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRY 494
+ + +A V ++T AP + + S++LSW +P P +YE++Y
Sbjct: 418 SPFS-PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQP---DQPNGVILDYELQY 473
Query: 495 YEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGE 554
YEK SE + +K+ TVTV LK YVFQ+RA + ++ + QT+ E
Sbjct: 474 YEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGR---YSGKMYFQTMTE 530
Query: 555 AASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFH-FK 613
A + Q ++ + + L+ L +V+ + + R + + + D+ + Y
Sbjct: 531 AEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRR-GFERADSEYTDKLQHYTSGHM 589
Query: 614 VPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELL 673
P + ++DP + D +AV FAKE+D V +E+ +G G FGE+C G L+LPG++E+
Sbjct: 590 TPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIF 649
Query: 674 VAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDG 733
VA+ L+ ++ QR FL+EA +GQFDH +++ LEGVVT+ + +MI+TE+M +G+LD
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 734 FLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRG- 792
FLR+++GQ QL+G+L G+A+ MKYL++M YVHR LAAR++LV+S+LVCK+S FG
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSR 769
Query: 793 --PRDRSEAVYTT-MSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWD 849
D S+ YT+ + G+ P W APE +Q+ F+SASDVWS+GI+MWEVM++GERPYWD
Sbjct: 770 FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 829
Query: 850 MSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEP 909
M+ QDVI A+E +RLPPP +CP+ LH+LMLDCWQKD RP+F QI + L KM+++P
Sbjct: 830 MTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNS 889
Query: 910 PKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMT 969
K PL DR + SF +V WLEA+ + +YK+SFA AG+ S + V++M
Sbjct: 890 LKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMM 949
Query: 970 AQDLVSLGISLAEHREALLSGISALQARVLQLQ 1002
+D++ +G++LA H++ +L+ I ++A++ Q+Q
Sbjct: 950 MEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQ 982
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 803 bits (2073), Expect = 0.0
Identities = 431/1001 (43%), Positives = 616/1001 (61%), Gaps = 27/1001 (2%)
Query: 7 PHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDE 66
P P L L L L LLL P EE L+D+K +EL WT+ P +GWEE+SG DE
Sbjct: 12 PPPGLLPLLPPLLLLPLLLLPAGCRALEET-LMDTKWVTSELAWTSHPESGWEEVSGYDE 70
Query: 67 HDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETF 126
PIRTYQVCNV E +Q+NWL+TG+I R QR++VEL+FT+RDC+SIP G+CKETF
Sbjct: 71 AMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETF 130
Query: 127 NVYYLETEADLGRGRPRLGGSRPR-KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSR 185
N++Y E ++D+ P K+DTIA DESF++ D G ++NT+VR GPLS+
Sbjct: 131 NLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSK 186
Query: 186 RGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSE 245
GF+LAFQD GAC++L+SVR +YK+C +T G A FP T + ++LV GTC+ ++
Sbjct: 187 AGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAV 246
Query: 246 GEPGSPPRMHCGADGEWLVPVGRCSCSAGFQE--RGDFCEACPPGFYKVSPRRPLCSPCP 303
E P +++C DGEW+VPVG C+C+ G + + C CPPG YK C PCP
Sbjct: 247 -EVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCP 305
Query: 304 EHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPA 363
+SR A++ C C +++ R+ +D ++CT PS PR + +++ + L+L W P
Sbjct: 306 PNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILE--WSEPR 363
Query: 364 DSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTV 423
D GGR D+ Y+++C +C G A AC C V F+PRQ GL ER + HL RYT
Sbjct: 364 DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423
Query: 424 RVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAP 483
V A+NGVSG + YA V ++T AP E +R S++LSW P P
Sbjct: 424 EVQAVNGVSGKSPLP-PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPP---ERP 479
Query: 484 GANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSF 543
+YE++Y+EK SE S V + +V + L+P RYV Q+RA + + +
Sbjct: 480 NGVILDYEMKYFEK--SEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQ---Y 534
Query: 544 NPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAH 603
+ E +T E SG++ + + V + +A LV + V+AI C + G
Sbjct: 535 SRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAI---VCLRKQRHGSDS 591
Query: 604 DEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGC 663
+ E + P + ++DP + D +AV FAKE+D V +E +G G FGE+C G
Sbjct: 592 EYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGR 651
Query: 664 LQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVT 723
L+ PGR+E+ VA+ L+ ++ QR FL+EA +GQFDH +I+RLEGVVT+ +MI+T
Sbjct: 652 LKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILT 711
Query: 724 EYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLV 783
E+M + ALD FLR ++GQ QL+G+L G+A+ MKYLSEM YVHR LAAR++LV+S+LV
Sbjct: 712 EFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLV 771
Query: 784 CKISGFGRG---PRDRSEAVYTT-MSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEV 839
CK+S FG D S+ YT+ + G+ P W APE + + F+SASDVWS+GI+MWEV
Sbjct: 772 CKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEV 831
Query: 840 MAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSI 899
M++GERPYWDMS QDVI AVE +RLPPP +CP LH+LMLDCW +D RP+FSQI +
Sbjct: 832 MSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNT 891
Query: 900 LSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGY 959
L K++++ K + PL DR + +F +VG WL+A+ + RYK+SF +AG+
Sbjct: 892 LDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGF 951
Query: 960 GSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQ 1000
S + VA+MTA+DL+ +G++LA H++ +LS I ++ ++ Q
Sbjct: 952 ASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQ 992
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 760 bits (1962), Expect = 0.0
Identities = 419/992 (42%), Positives = 589/992 (59%), Gaps = 44/992 (4%)
Query: 20 CLALLLGPWRPGTA----EEVILLDSKASQAELGWTALP-SNGWEEISGVDEHDRPIRTY 74
C ALL G A +EV+LLD A+ ELGW P GW+ + + +D PI Y
Sbjct: 9 CFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPIYMY 67
Query: 75 QVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETE 134
VCNV+ +QDNWL+T W+ RG +RIF+EL+FT+RDC+S PG A +CKETFN+YY E++
Sbjct: 68 SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESD 127
Query: 135 ADLGRG-RPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQ 193
D G + RL KIDTIA DE D R +KLN E R +GPL+R+GF+LAFQ
Sbjct: 128 LDYGTNFQKRLF----TKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQ 183
Query: 194 DVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSP-P 252
D+GACVAL+SVRVYYK+C ++GLA FP T A S +L VAGTCV H+ PG P
Sbjct: 184 DIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEP 243
Query: 253 RMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENA 312
RMHC DGEWLVP+G+C C AG+++ D C+AC PGF+K C CPEH+
Sbjct: 244 RMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEG 303
Query: 313 STFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVT 372
+T C C++ + R+P DP S CTRPPSAP L + + LRW PP DSGGR D+
Sbjct: 304 ATSCECEEGFFRAPQDPASMPCTRPPSAPHYL--TAVGMGAKVELRWTPPQDSGGREDIV 361
Query: 373 YSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVS 432
YS+ C +C E +G C PC V + GL + T+ L P YT V A NGVS
Sbjct: 362 YSVTCEQCWPE--SGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVS 419
Query: 433 GPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEI 492
G + A V+++ E ++R + S+S+SW P P + +YE+
Sbjct: 420 GLVTSRSFRTASVSINQT-----EPPKVRLEGRSTTSLSVSWSIPPPQQS---RVWKYEV 471
Query: 493 RYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSI-EVQT 551
Y +KG S +Y++ +T +VT+ +L P T Y+ Q++A + E Q + E QT
Sbjct: 472 TYRKKGDSN-SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQ----EGQGAGSKVHEFQT 526
Query: 552 LGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFH 611
L SG+ + V VV + L +G I RR K E++YF
Sbjct: 527 LSPEGSGNLAVIGGVAVGVVLLLVLAGVG-----FFIHRRR----KNQRARQSPEDVYFS 577
Query: 612 FKVPTR--RTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLP-G 668
+ +T++DP + D QAV F E+ VT ++ +G G FGE+ G L+ G
Sbjct: 578 KSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSG 637
Query: 669 RQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSH 728
++E+ VA+ L+ ++ QR+ FL EA +GQF H +I+RLEGV+++ +MI+TEYM +
Sbjct: 638 KKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMEN 697
Query: 729 GALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISG 788
GALD FLR +G+ QL+G+L G+A+ MKYL+ M YVHR LAAR++LV+S+LVCK+S
Sbjct: 698 GALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSD 757
Query: 789 FG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERP 846
FG R D EA YTT G+ P W APE + + F+SASDVWSFGI+MWEVM +GERP
Sbjct: 758 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERP 817
Query: 847 YWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQD 906
YW++S +V+KA+ DGFRLP P +CP+ +++LM+ CWQ++ RP+F+ I SIL K+++
Sbjct: 818 YWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRA 877
Query: 907 PEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVA 966
P+ K PR L + S F +V WLE++ + +Y + F AAGY ++E V
Sbjct: 878 PDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVV 937
Query: 967 EMTAQDLVSLGISLAEHREALLSGISALQARV 998
+MT D+ +G+ L H++ + + L+ +V
Sbjct: 938 QMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQV 969
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 731 bits (1887), Expect = 0.0
Identities = 410/1003 (40%), Positives = 576/1003 (57%), Gaps = 49/1003 (4%)
Query: 10 LRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPS--NGWEEISGVDEH 67
LR+ LC L AL E LL++K A+L W P WEE+SG+DE
Sbjct: 3 LRVLLCWASLAAAL-----------EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEE 51
Query: 68 DRPIRTYQVCNVLE-PNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETF 126
+RTY+VC+V P Q +WL+TGW+ R ++ L+FT+ +C S+P A +CKETF
Sbjct: 52 QHSVRTYEVCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETF 111
Query: 127 NVYYLETEADLGRGRPRLGGSRPR-KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSR 185
V+Y E++AD P K+DT+AA+ + E K+N + +GPLS+
Sbjct: 112 TVFYYESDADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSK 171
Query: 186 RGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSE 245
GF+LAFQD GAC+AL+S+ ++YK+C L FP T +V VAG+CV +
Sbjct: 172 AGFYLAFQDQGACMALLSLHLFYKKCAQLTVNLTRFPETVPREL---VVPVAGSCVVDAV 228
Query: 246 GEPGSPPRMHCGADGEWLV-PVGRCSCSAGFQ--ERGDFCEACPPGFYKVSPRRPLCSPC 302
PG P ++C DG+W PV CSC+ GF+ E C AC G +K C PC
Sbjct: 229 PAPGPSPSLYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPC 288
Query: 303 PEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPP 362
P +S + S C C+ Y R+ TDP A CT PPSAPR + L+ S L L W P
Sbjct: 289 PANSHSNTIGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSL--HLEWSAP 346
Query: 363 ADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYT 422
+SGGR D+TY+L C C P G+C PCG + F P L E + LRP YT
Sbjct: 347 LESGGREDLTYALRCRECR---PGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYT 403
Query: 423 VRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGA 482
V ALNGVS A + V V+T P +IR R P S+SL+W P A
Sbjct: 404 FEVTALNGVSS-LATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVP---RA 459
Query: 483 PGANDTEYEIRYYEKG-QSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASP---GPSW 538
P +YE++Y+EKG + + +KT + LK Y+ Q+RA S GP
Sbjct: 460 PSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGP-- 517
Query: 539 EAQSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKG 598
F QT + + G R+Q I T V L+++ V++VL + ++
Sbjct: 518 ----FGQEHHSQTQLDESEGWREQLALIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAE 573
Query: 599 GGDAHDEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGE 658
D H + + KV ++DP + D +AV FAKE+D V +E +G G FGE
Sbjct: 574 YSDKHGQYLIGHGTKV-----YIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
Query: 659 LCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGST 718
+C G L+ PG++E VA+ L+ ++ QR FL+EA +GQF+H +I+RLEGVVT
Sbjct: 629 VCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMP 688
Query: 719 LMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLV 778
+MI+TE+M +GALD FLR ++GQ QL+G+L G+AS M+YL+EM YVHR LAAR++LV
Sbjct: 689 VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILV 748
Query: 779 SSDLVCKISGFGRG---PRDRSEAVYTT-MSGRSPALWAAPETLQFGHFSSASDVWSFGI 834
+S+LVCK+S FG + S+ YT+ + G+ P W APE + F F+SASD WS+GI
Sbjct: 749 NSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGI 808
Query: 835 IMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFS 894
+MWEVM+FGERPYWDMS QDVI A+E +RLPPP +CP LH+LMLDCWQKD RPRF
Sbjct: 809 VMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFP 868
Query: 895 QIHSILSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSF 954
Q+ S L KM+++P K PL D+ + +FGSVG WL A+ + RY++SF
Sbjct: 869 QVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESF 928
Query: 955 AAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQAR 997
AAAG+GS E V++++A+DL+ +G++LA H++ +L+ + ++++
Sbjct: 929 AAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQ 971
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 701 bits (1809), Expect = 0.0
Identities = 409/990 (41%), Positives = 571/990 (57%), Gaps = 45/990 (4%)
Query: 23 LLLGPWRPGT-AEEVILLDSKASQAELGWTA-LPSNGWEEISGVDEHDRPIRTYQVCNVL 80
LL P PG A+EV L+D+ +Q ELGW P +GW E + + P+ YQ C +
Sbjct: 14 LLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQDCPMQ 72
Query: 81 -EPNQDNWLQTGWISRGR-GQRIFVELQFTLRDCSSIPGAAGT--CKETFNVYYLETEAD 136
+ D+WL++ WI RG R+ VELQFT+RDC S PG AG CKETFN+ Y+E++ D
Sbjct: 73 GRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQD 132
Query: 137 LGRGRPRLGGSRP--RKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQD 194
+G + RP +K+ T+AAD+SFT DL +KLN E +G L+RRG +LAF +
Sbjct: 133 VG-----IQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHN 187
Query: 195 VGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEP--GSPP 252
GACVALVSVRV+Y++C T+ GLA FP T A LVEVAGTC+ H+ P P
Sbjct: 188 PGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPA--GLVEVAGTCLPHARASPRPSGAP 245
Query: 253 RMHCGADGEWLVPVGRCSCSAGFQE--RGDFCEACPPGFYKVSPRRPLCSPCPEHSRALE 310
RMHC DGEWLVPVGRC C G++E G+ C ACP G Y++ P C CP+ S A
Sbjct: 246 RMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAES 305
Query: 311 NASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSD 370
+T C C+ + R+P + P +CT PPSAPR+L +S S + L LRW PPAD+GGR D
Sbjct: 306 EGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQL--SLRWEPPADTGGRQD 363
Query: 371 VTYSLLCLRC-GREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALN 429
V YS+ C +C G G C+PCG V F P GL A + L P A YT V A N
Sbjct: 364 VRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQN 423
Query: 430 GVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTE 489
GVSG ++G V++S G +R + EP+ + L+W P +PGAN T
Sbjct: 424 GVSG-LGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPR-SPGANLT- 480
Query: 490 YEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASP-GPSWEAQSFNPSIE 548
YE+ Q E+ Y MV P V +T L+P T Y+ ++R +P GP F+P E
Sbjct: 481 YELHVLN--QDEERYQMVLE--PRVLLTELQPDTTYIVRVRMLTPLGPG----PFSPDHE 532
Query: 549 VQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVM--SVLAIWRRPCSYGKGGGDAHDEE 606
+T + G V+ + + A L+LG ++ S A +R D E+
Sbjct: 533 FRTSPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDRED 592
Query: 607 ELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQL 666
+L+ + ++D Q+ D Q F +ELD + ++ +G G FGE+ G L+L
Sbjct: 593 KLWL-------KPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRL 645
Query: 667 PGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYM 726
P + VA+ L+D++ Q FL EA +GQF H HI+ LEGVVT+ +MI+TE+M
Sbjct: 646 PSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFM 705
Query: 727 SHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKI 786
+GALD FLR E QLV GQL+ +L G+AS M YLS YVHR LAAR++LV+ +L CK+
Sbjct: 706 ENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKV 765
Query: 787 SGFGRGPR-DRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGER 845
S FG D + Y T G+ P W APE + F++ASDVWSFGI+MWEV++FG++
Sbjct: 766 SDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDK 825
Query: 846 PYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905
PY +MS Q+V+K++EDG+RLPPP +CP L+ LM +CW D RP F ++ + L +++
Sbjct: 826 PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLA 885
Query: 906 DPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAV 965
+P + PR L + S + +V WLE++ + RY F +AG ++E V
Sbjct: 886 NPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECV 945
Query: 966 AEMTAQDLVSLGISLAEHREALLSGISALQ 995
E+TA+DL +GI+L H++ +L I +
Sbjct: 946 LELTAEDLTQMGITLPGHQKRILCSIQGFK 975
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 671 bits (1730), Expect = 0.0
Identities = 395/1017 (38%), Positives = 563/1017 (55%), Gaps = 81/1017 (7%)
Query: 33 AEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEP----NQDNWL 88
A E +LLD+ +E+GW P GW+E+S +D+ R RT++ C+V QDNWL
Sbjct: 31 ALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGAPPGTGQDNWL 90
Query: 89 QTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEA-DLGRGRPRLGGS 147
QT ++ R QR + L F++R CSS+ + GTC+ETF +YY + E D
Sbjct: 91 QTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPDSPDSVSSWHLK 150
Query: 148 RPRKIDTIAADESFTQGD-----------------LGERK-MKLNTEVREIGPLSRRGFH 189
R K+DTIAADESF G+R ++LN + R GPL++RGF+
Sbjct: 151 RWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSFGPLTQRGFY 210
Query: 190 LAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAF-STLVEVAGTCVAHSEGEP 248
+AFQD GAC+ALV+VR++ C A +R A+FP T A A ++LV GTCVAH+E E
Sbjct: 211 VAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGTCVAHAEPEE 270
Query: 249 --------GSPPRMHCGADGEWLVPVGRCSCSAGFQE-RGD-FCEACPPGFYKVSPRRPL 298
GSPPR+HC +G+W+V VG C C G+Q RGD C+ACP G YK S
Sbjct: 271 DGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLYKSSAGNAP 330
Query: 299 CSPCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLR 358
CSPCP S A A+ C C + + R+ +DPP A CT PPSAP++L + + S L+L
Sbjct: 331 CSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQGSALMLH-- 388
Query: 359 WLPPADSGGRSDVTYSLLCLRC-GREGPA----GACEPCGPRVAFLPRQAGLRERAATLL 413
W P + GGR D+ ++++C C GR+ PA G C C V F PRQ GL E +
Sbjct: 389 WRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTESRVLVG 448
Query: 414 HLRPGARYTVRVAALNGVSG-----PAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQ 468
LR Y + V A+NGVS P AAA + VST P + +
Sbjct: 449 GLRAHVPYILEVQAVNGVSELSPDPPQAAA------INVSTSHEVPSAVPVVHQVSRASN 502
Query: 469 SVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQ 528
S+++SW +P N +Y++RYY++ + E + + T TVT L P Y FQ
Sbjct: 503 SITVSWPQP---DQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQ 559
Query: 529 IRA---ASPGPSWEAQSFNPSIEVQTL--GEAASGSRDQSPAIVVTVVTISALLVLGSVM 583
+RA A GP + + QTL GE +S ++ ++ +++ A L+L ++
Sbjct: 560 VRARTAAGHGP------YGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAIT 613
Query: 584 SVLAIWRRPCSYGKGGGDAHDEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAK 643
+ +++R K G + E+ + + ++DP + D QA+ A+E+D
Sbjct: 614 VLAVVFQR-----KRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPA 668
Query: 644 SVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDH 703
+ +E +G G FGE+ G LQ GR+E VA+ L ++S ++ FL A LGQF H
Sbjct: 669 YIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQH 728
Query: 704 SHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSE 763
+I+RLEGVVT+ LM++TE+M G LD FLR+ EGQ + QL+ + G+A+AM+YLS
Sbjct: 729 PNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSS 788
Query: 764 MGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFGHF 823
+VHR L+A VLV+S LVCK++ G P+ S + WAAPE + G
Sbjct: 789 FAFVHRSLSAHSVLVNSHLVCKVARLGHSPQGPSCLLR----------WAAPEVIAHGKH 838
Query: 824 SSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCW 883
+++SDVWSFGI+MWEVM++GERPYWDMS Q+V+ A+E FRLPPP CP LH LMLD W
Sbjct: 839 TTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTW 898
Query: 884 QKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLE 943
QKD RP F Q+ + KM++ P+ + RP L FP S AWL
Sbjct: 899 QKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLS 958
Query: 944 ALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQ 1000
A+ L Y+D+F+ G + VA+++ +DL +LGI+LA H++ LL I LQ + Q
Sbjct: 959 AIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQ 1015
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 591 bits (1523), Expect = e-168
Identities = 283/283 (100%), Positives = 283/283 (100%)
Query: 1 METCAGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEE 60
METCAGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEE
Sbjct: 1 METCAGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEE 60
Query: 61 ISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAG 120
ISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAG
Sbjct: 61 ISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAG 120
Query: 121 TCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREI 180
TCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREI
Sbjct: 121 TCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREI 180
Query: 181 GPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTC 240
GPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTC
Sbjct: 181 GPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTC 240
Query: 241 VAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCE 283
VAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCE
Sbjct: 241 VAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCE 283
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 521 bits (1343), Expect = e-147
Identities = 263/522 (50%), Positives = 355/522 (68%), Gaps = 22/522 (4%)
Query: 18 QLCLALLL--------GPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDR 69
QL + LLL G P + EV LLDSK Q ELGW + PS+GWEEISGVDEH
Sbjct: 4 QLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYT 63
Query: 70 PIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVY 129
PIRTYQVCNV++ +Q+NWL+T W+ R Q+I+VEL+FTLRDC+SIP GTCKETFN+Y
Sbjct: 64 PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLY 123
Query: 130 YLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFH 189
Y+E++ D G + + KIDTIAADESFTQ DLG+R +KLNTE+RE+GP++++GF+
Sbjct: 124 YMESDDDHG---VKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Query: 190 LAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPG 249
LAFQDVGACVALVSVRVY+K+C TV+ LA FP T + +LVEV G+CV +S+ E
Sbjct: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDS-QSLVEVRGSCVNNSKEE-- 237
Query: 250 SPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRAL 309
PPRM+C +GEWLVP+G+CSC+AG++ERG C+AC PGFYK C+ CP HS
Sbjct: 238 DPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQ 297
Query: 310 ENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRS 369
E+ S C C+++Y R+ DPPS +CTRPPS+PR++ +++ + ++L W P D+GGR
Sbjct: 298 EDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSW--PLDTGGRK 355
Query: 370 DVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALN 429
DVT++++C +CG CEPC P V FLPRQ GL T+ L YT + A+N
Sbjct: 356 DVTFNIICKKCGWN--IKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
Query: 430 GVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTE 489
GVS ++ +A V+++T AP I++DR S+SLSW+EP P +
Sbjct: 414 GVS-ELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEP---EHPNGIILD 469
Query: 490 YEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRA 531
YE++YYEK + E +Y++++ VT+++LKP T YVFQIRA
Sbjct: 470 YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 424 bits (1090), Expect = e-118
Identities = 204/398 (51%), Positives = 271/398 (68%), Gaps = 9/398 (2%)
Query: 35 EVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWIS 94
EV LLD+ + GW P++GW+ I+ VDE +PI TYQVCNV+ PNQ+NWL+T W+
Sbjct: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
Query: 95 RGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDT 154
R +R++ E++FTLRDC+S+PG GTCKETFN+YYLE++ DLG S+ KIDT
Sbjct: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQE---SQFLKIDT 147
Query: 155 IAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRAT 214
IAADESFT DLG R++KLNTEVR +GPLS+RGF+LAFQD+GAC+A++S+R+YYK+C A
Sbjct: 148 IAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAM 207
Query: 215 VRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAG 274
VR LA F + S+LVEV G CV HSE P+M+C A+GEWLVP+G+C CSAG
Sbjct: 208 VRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER--DTPKMYCSAEGEWLVPIGKCVCSAG 265
Query: 275 FQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASC 334
++ER D C AC GFYK +P LC+ CP HS + A+ C C SY R+ DPPS++C
Sbjct: 266 YEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSAC 325
Query: 335 TRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGP 394
TRPPSAP +L S++ + + L W PP D GGRSD+TY+ +C RC CE CG
Sbjct: 326 TRPPSAPVNLISSVNGTSVT--LEWAPPLDPGGRSDITYNAVCRRC--PWALSRCEACGS 381
Query: 395 RVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVS 432
F+P+Q L + + + +L Y+ + A+NGVS
Sbjct: 382 GTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVS 419
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 202 bits (513), Expect = 2e-51
Identities = 106/268 (39%), Positives = 155/268 (57%), Gaps = 1/268 (0%)
Query: 639 ELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTL 698
E+ + + L R +G G+FG++ G P L VA+ ++ SDS R FL EALT+
Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 497
Query: 699 GQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAM 758
QFDH HIV+L GV+T + + I+ E + G L FL+ + L L+ L++A+
Sbjct: 498 RQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 556
Query: 759 KYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETL 818
YL +VHR +AAR+VLVSS+ K+ FG Y G+ P W APE++
Sbjct: 557 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI 616
Query: 819 QFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRL 878
F F+SASDVW FG+ MWE++ G +P+ + DVI +E+G RLP P NCP L+ L
Sbjct: 617 NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSL 676
Query: 879 MLDCWQKDPGERPRFSQIHSILSKMVQD 906
M CW DP RPRF+++ + LS ++++
Sbjct: 677 MTKCWAYDPSRRPRFTELKAQLSTILEE 704
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 202 bits (513), Expect = 2e-51
Identities = 106/268 (39%), Positives = 155/268 (57%), Gaps = 1/268 (0%)
Query: 639 ELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTL 698
E+ + + L R +G G+FG++ G P L VA+ ++ SDS R FL EALT+
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475
Query: 699 GQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAM 758
QFDH HIV+L GV+T + + I+ E + G L FL+ + L L+ L++A+
Sbjct: 476 RQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
Query: 759 KYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETL 818
YL +VHR +AAR+VLVSS+ K+ FG Y G+ P W APE++
Sbjct: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI 594
Query: 819 QFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRL 878
F F+SASDVW FG+ MWE++ G +P+ + DVI +E+G RLP P NCP L+ L
Sbjct: 595 NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSL 654
Query: 879 MLDCWQKDPGERPRFSQIHSILSKMVQD 906
M CW DP RPRF+++ + LS ++++
Sbjct: 655 MTKCWAYDPSRRPRFTELKAQLSTILEE 682
>gi|65506745 neurotrophic tyrosine kinase, receptor, type 2 isoform
c precursor [Homo sapiens]
Length = 822
Score = 187 bits (476), Expect = 3e-47
Identities = 104/286 (36%), Positives = 159/286 (55%), Gaps = 18/286 (6%)
Query: 636 FAKELDAKSVTLERSLGGGRFGELCCG-CLQL-PGRQELLVAVHMLRDSASDSQRLGFLA 693
F + + ++ L+R LG G FG++ C L P + ++LVAV L+D ASD+ R F
Sbjct: 529 FVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKD-ASDNARKDFHR 587
Query: 694 EALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRH--------EG----Q 741
EA L H HIV+ GV G L++V EYM HG L+ FLR H EG +
Sbjct: 588 EAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTE 647
Query: 742 LVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVY 801
L Q++ + +A+ M YL+ +VHR LA R+ LV +L+ KI FG RD Y
Sbjct: 648 LTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMS-RDVYSTDY 706
Query: 802 TTMSGRS--PALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAV 859
+ G + P W PE++ + F++ SDVWS G+++WE+ +G++P++ +S +VI+ +
Sbjct: 707 YRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECI 766
Query: 860 EDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905
G L PR CP ++ LML CWQ++P R IH++L + +
Sbjct: 767 TQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAK 812
>gi|21361306 neurotrophic tyrosine kinase, receptor, type 2 isoform
a precursor [Homo sapiens]
Length = 838
Score = 187 bits (476), Expect = 3e-47
Identities = 104/286 (36%), Positives = 159/286 (55%), Gaps = 18/286 (6%)
Query: 636 FAKELDAKSVTLERSLGGGRFGELCCG-CLQL-PGRQELLVAVHMLRDSASDSQRLGFLA 693
F + + ++ L+R LG G FG++ C L P + ++LVAV L+D ASD+ R F
Sbjct: 545 FVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKD-ASDNARKDFHR 603
Query: 694 EALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRH--------EG----Q 741
EA L H HIV+ GV G L++V EYM HG L+ FLR H EG +
Sbjct: 604 EAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTE 663
Query: 742 LVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVY 801
L Q++ + +A+ M YL+ +VHR LA R+ LV +L+ KI FG RD Y
Sbjct: 664 LTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMS-RDVYSTDY 722
Query: 802 TTMSGRS--PALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAV 859
+ G + P W PE++ + F++ SDVWS G+++WE+ +G++P++ +S +VI+ +
Sbjct: 723 YRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECI 782
Query: 860 EDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905
G L PR CP ++ LML CWQ++P R IH++L + +
Sbjct: 783 TQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAK 828
>gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like
domains 1 [Homo sapiens]
Length = 1138
Score = 186 bits (473), Expect = 7e-47
Identities = 154/537 (28%), Positives = 244/537 (45%), Gaps = 66/537 (12%)
Query: 408 RAATLLHLRPGARYTVRVAALN-GVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVE 466
R A L L PG Y + V + + GPA+ + +GP AP + +
Sbjct: 603 RTALLTGLTPGTHYQLDVQLYHCTLLGPASPPAHV---LLPPSGPPAP---RHLHAQALS 656
Query: 467 PQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTN-LKPATRY 525
+ L+W+ P PG G + + V T T+ L +TRY
Sbjct: 657 DSEIQLTWKHP--EALPGPISKYVVEVQVAGGAGDPLWIDVDRPEETSTIIRGLNASTRY 714
Query: 526 VFQIRAASPGPSWEAQSFNPSIEVQTLGE-------------AASGSRDQSPAIVVTVVT 572
+F++RA+ G ++ ++E TLG A G Q VV V+
Sbjct: 715 LFRMRASIQGLG----DWSNTVEESTLGNGLQAEGPVQESRAAEEGLDQQLILAVVGSVS 770
Query: 573 ISALLVLGSVMSVLAIWRRPC-------SYGKGGGDAHDEEELYFHFKVPTRRTFLDPQS 625
+ L +L ++++++ I RR C +Y G G EE F T P+
Sbjct: 771 ATCLTILAALLTLVCI-RRSCLHRRRTFTYQSGSG-----EETILQFSSGTLTLTRRPK- 823
Query: 626 CGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASD 685
LQ L L+ + +T E +G G FG++ ++ G + + A+ ML++ AS+
Sbjct: 824 ----LQPEPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLK-MNAAIKMLKEYASE 878
Query: 686 SQRLGFLAEALTLGQFDHS-HIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHE----- 739
+ F E L + H +I+ L G L I EY +G L FLR+
Sbjct: 879 NDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLETD 938
Query: 740 ----------GQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGF 789
L + QL+ A+ M+YLSE ++HR LAAR+VLV +L KI+ F
Sbjct: 939 PAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADF 998
Query: 790 GRGPRDRSEAVYTTMS-GRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYW 848
G R E VY + GR P W A E+L + +++ SDVWSFG+++WE+++ G PY
Sbjct: 999 GLS---RGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYC 1055
Query: 849 DMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905
M+ ++ + + G+R+ PRNC + ++ LM CW+ P ERP F+QI L +M++
Sbjct: 1056 GMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLE 1112
>gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isoform
1 [Homo sapiens]
Length = 790
Score = 184 bits (468), Expect = 3e-46
Identities = 106/284 (37%), Positives = 156/284 (54%), Gaps = 22/284 (7%)
Query: 643 KSVTLERSLGGGRFGELC---CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLG 699
+ + L+ LG G FG++ C L LP + ++LVAV L++ AS+S R F EA L
Sbjct: 502 RDIVLKWELGEGAFGKVFLAECHNL-LPEQDKMLVAVKALKE-ASESARQDFQREAELLT 559
Query: 700 QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRH--------------EGQLVAG 745
H HIVR GV T G L++V EYM HG L+ FLR H G L G
Sbjct: 560 MLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLG 619
Query: 746 QLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMS 805
QL+ + +A+ M YL+ + +VHR LA R+ LV LV KI FG RD Y +
Sbjct: 620 QLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS-RDIYSTDYYRVG 678
Query: 806 GRS--PALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGF 863
GR+ P W PE++ + F++ SDVWSFG+++WE+ +G++P++ +S + I + G
Sbjct: 679 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 738
Query: 864 RLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDP 907
L PR CP ++ +M CWQ++P +R +H+ L + Q P
Sbjct: 739 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAP 782
>gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isoform 2
[Homo sapiens]
Length = 796
Score = 184 bits (468), Expect = 3e-46
Identities = 106/284 (37%), Positives = 156/284 (54%), Gaps = 22/284 (7%)
Query: 643 KSVTLERSLGGGRFGELC---CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLG 699
+ + L+ LG G FG++ C L LP + ++LVAV L++ AS+S R F EA L
Sbjct: 508 RDIVLKWELGEGAFGKVFLAECHNL-LPEQDKMLVAVKALKE-ASESARQDFQREAELLT 565
Query: 700 QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRH--------------EGQLVAG 745
H HIVR GV T G L++V EYM HG L+ FLR H G L G
Sbjct: 566 MLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLG 625
Query: 746 QLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMS 805
QL+ + +A+ M YL+ + +VHR LA R+ LV LV KI FG RD Y +
Sbjct: 626 QLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS-RDIYSTDYYRVG 684
Query: 806 GRS--PALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGF 863
GR+ P W PE++ + F++ SDVWSFG+++WE+ +G++P++ +S + I + G
Sbjct: 685 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 744
Query: 864 RLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDP 907
L PR CP ++ +M CWQ++P +R +H+ L + Q P
Sbjct: 745 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAP 788
>gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isoform
3 [Homo sapiens]
Length = 760
Score = 184 bits (468), Expect = 3e-46
Identities = 106/284 (37%), Positives = 156/284 (54%), Gaps = 22/284 (7%)
Query: 643 KSVTLERSLGGGRFGELC---CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLG 699
+ + L+ LG G FG++ C L LP + ++LVAV L++ AS+S R F EA L
Sbjct: 472 RDIVLKWELGEGAFGKVFLAECHNL-LPEQDKMLVAVKALKE-ASESARQDFQREAELLT 529
Query: 700 QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRH--------------EGQLVAG 745
H HIVR GV T G L++V EYM HG L+ FLR H G L G
Sbjct: 530 MLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLG 589
Query: 746 QLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMS 805
QL+ + +A+ M YL+ + +VHR LA R+ LV LV KI FG RD Y +
Sbjct: 590 QLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS-RDIYSTDYYRVG 648
Query: 806 GRS--PALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGF 863
GR+ P W PE++ + F++ SDVWSFG+++WE+ +G++P++ +S + I + G
Sbjct: 649 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 708
Query: 864 RLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDP 907
L PR CP ++ +M CWQ++P +R +H+ L + Q P
Sbjct: 709 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAP 752
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 183 bits (465), Expect = 6e-46
Identities = 102/266 (38%), Positives = 154/266 (57%), Gaps = 10/266 (3%)
Query: 637 AKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEAL 696
A E+ +S+ LE+ LG G+FGE+ + VAV ++ + + FLAEA
Sbjct: 254 AWEIPRESLKLEKKLGAGQFGEVWMATYN----KHTKVAVKTMKPGSMSVE--AFLAEAN 307
Query: 697 TLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEG-QLVAGQLMGLLPGLA 755
+ H +V+L VVT+ + I+TE+M+ G+L FL+ EG + +L+ +A
Sbjct: 308 VMKTLQHDKLVKLHAVVTK-EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIA 366
Query: 756 SAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSG-RSPALWAA 814
M ++ + Y+HR L A ++LVS+ LVCKI+ FG R + YT G + P W A
Sbjct: 367 EGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLA-RVIEDNEYTAREGAKFPIKWTA 425
Query: 815 PETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNL 874
PE + FG F+ SDVWSFGI++ E++ +G PY MS +VI+A+E G+R+P P NCP
Sbjct: 426 PEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEE 485
Query: 875 LHRLMLDCWQKDPGERPRFSQIHSIL 900
L+ +M+ CW+ P ERP F I S+L
Sbjct: 486 LYNIMMRCWKNRPEERPTFEYIQSVL 511
>gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens]
Length = 694
Score = 182 bits (462), Expect = 1e-45
Identities = 105/266 (39%), Positives = 146/266 (54%), Gaps = 6/266 (2%)
Query: 640 LDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLG 699
L+ + + L +G G FGE+ G L+ LVAV R++ + FL EA L
Sbjct: 428 LNHEDLVLGEQIGRGNFGEVFSGRLRA---DNTLVAVKSCRETLPPDLKAKFLQEARILK 484
Query: 700 QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMK 759
Q+ H +IVRL GV T+ + IV E + G FLR +L L+ ++ A+ M+
Sbjct: 485 QYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGME 544
Query: 760 YLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSG--RSPALWAAPET 817
YL +HR LAAR+ LV+ V KIS FG R+ ++ VY G + P W APE
Sbjct: 545 YLESKCCIHRDLAARNCLVTEKNVLKISDFGMS-REEADGVYAASGGLRQVPVKWTAPEA 603
Query: 818 LQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHR 877
L +G +SS SDVWSFGI++WE + G PY ++S Q + VE G RLP P CP+ + R
Sbjct: 604 LNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 663
Query: 878 LMLDCWQKDPGERPRFSQIHSILSKM 903
LM CW +PG+RP FS I+ L +
Sbjct: 664 LMEQCWAYEPGQRPSFSTIYQELQSI 689
>gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens]
Length = 752
Score = 182 bits (462), Expect = 1e-45
Identities = 105/266 (39%), Positives = 146/266 (54%), Gaps = 6/266 (2%)
Query: 640 LDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLG 699
L+ + + L +G G FGE+ G L+ LVAV R++ + FL EA L
Sbjct: 486 LNHEDLVLGEQIGRGNFGEVFSGRLRA---DNTLVAVKSCRETLPPDLKAKFLQEARILK 542
Query: 700 QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMK 759
Q+ H +IVRL GV T+ + IV E + G FLR +L L+ ++ A+ M+
Sbjct: 543 QYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGME 602
Query: 760 YLSEMGYVHRGLAARHVLVSSDLVCKISGFGRGPRDRSEAVYTTMSG--RSPALWAAPET 817
YL +HR LAAR+ LV+ V KIS FG R+ ++ VY G + P W APE
Sbjct: 603 YLESKCCIHRDLAARNCLVTEKNVLKISDFGMS-REEADGVYAASGGLRQVPVKWTAPEA 661
Query: 818 LQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHR 877
L +G +SS SDVWSFGI++WE + G PY ++S Q + VE G RLP P CP+ + R
Sbjct: 662 LNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 721
Query: 878 LMLDCWQKDPGERPRFSQIHSILSKM 903
LM CW +PG+RP FS I+ L +
Sbjct: 722 LMEQCWAYEPGQRPSFSTIYQELQSI 747
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,729,390
Number of Sequences: 37866
Number of extensions: 2311308
Number of successful extensions: 9365
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 299
Number of HSP's successfully gapped in prelim test: 565
Number of HSP's that attempted gapping in prelim test: 7225
Number of HSP's gapped (non-prelim): 1764
length of query: 1008
length of database: 18,247,518
effective HSP length: 112
effective length of query: 896
effective length of database: 14,006,526
effective search space: 12549847296
effective search space used: 12549847296
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.