Search of human proteins with 150378537

Search of human proteins with 150378537

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|150378537 hypothetical protein LOC55184 [Homo sapiens]
         (752 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|150378537 hypothetical protein LOC55184 [Homo sapiens]            1548   0.0  
gi|62988328 ankyrin repeat domain 50 [Homo sapiens]                    51   3e-06
gi|18252778 ankyrin repeat and SOCS box-containing protein 2 [Ho...    50   8e-06
gi|157743284 ankyrin repeat domain 52 [Homo sapiens]                   49   2e-05
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    49   2e-05
gi|20270347 ankyrin repeat domain 54 [Homo sapiens]                    48   4e-05
gi|55742857 ankyrin repeat domain 6 [Homo sapiens]                     47   7e-05
gi|89363047 death-associated protein kinase 1 [Homo sapiens]           47   9e-05
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo...    47   9e-05
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]     47   9e-05
gi|38327522 cardiac ankyrin repeat protein [Homo sapiens]              46   1e-04
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi...    45   2e-04
gi|103471993 huntingtin interacting protein 14 [Homo sapiens]          45   2e-04
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       44   4e-04
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       44   4e-04
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       44   4e-04
gi|239757617 PREDICTED: similar to hCG1793014 [Homo sapiens]           44   7e-04
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       43   0.001
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       43   0.001
gi|41327752 diabetes related ankyrin repeat protein [Homo sapiens]     43   0.001
gi|67906195 ankyrin repeat and sterile alpha motif domain contai...    42   0.002
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  42   0.002
gi|4502753 cyclin-dependent kinase inhibitor 2D [Homo sapiens]         42   0.003
gi|17981702 cyclin-dependent kinase inhibitor 2D [Homo sapiens]        42   0.003
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         42   0.003
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ...    42   0.003
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]                     42   0.003
gi|223634006 hypothetical protein LOC441869 [Homo sapiens]             41   0.004
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    41   0.004
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    41   0.004

>gi|150378537 hypothetical protein LOC55184 [Homo sapiens]
          Length = 752

 Score = 1548 bits (4008), Expect = 0.0
 Identities = 752/752 (100%), Positives = 752/752 (100%)

Query: 1   MTAGSVCVPQIIPLRVPQPGKANHEIDNNTLLEMKSDTPDVNIYYTLDGSKPEFLKRIGY 60
           MTAGSVCVPQIIPLRVPQPGKANHEIDNNTLLEMKSDTPDVNIYYTLDGSKPEFLKRIGY
Sbjct: 1   MTAGSVCVPQIIPLRVPQPGKANHEIDNNTLLEMKSDTPDVNIYYTLDGSKPEFLKRIGY 60

Query: 61  GENNTFKYIKPITLPDGKIQVKAIAVSKDCRQSGIVTKVFHVDYEPPNIVSPEDNVENVL 120
           GENNTFKYIKPITLPDGKIQVKAIAVSKDCRQSGIVTKVFHVDYEPPNIVSPEDNVENVL
Sbjct: 61  GENNTFKYIKPITLPDGKIQVKAIAVSKDCRQSGIVTKVFHVDYEPPNIVSPEDNVENVL 120

Query: 121 KDSSRQEFKNGFVGSKLKKKYKNSENQRSWNVNLRKFPESPLEIPAYGGGSGSRPPTRQS 180
           KDSSRQEFKNGFVGSKLKKKYKNSENQRSWNVNLRKFPESPLEIPAYGGGSGSRPPTRQS
Sbjct: 121 KDSSRQEFKNGFVGSKLKKKYKNSENQRSWNVNLRKFPESPLEIPAYGGGSGSRPPTRQS 180

Query: 181 QSPGFAHVSGQKCLTSTEIMRIQRETDFLKCAHCLAPRPSDPFARFCQECGSPVPPIFGC 240
           QSPGFAHVSGQKCLTSTEIMRIQRETDFLKCAHCLAPRPSDPFARFCQECGSPVPPIFGC
Sbjct: 181 QSPGFAHVSGQKCLTSTEIMRIQRETDFLKCAHCLAPRPSDPFARFCQECGSPVPPIFGC 240

Query: 241 RLPPPEGAQMGLCAECRSLVPMNTPICVVCEAPLALQLQPQASLHLKEKVICRACGTGNP 300
           RLPPPEGAQMGLCAECRSLVPMNTPICVVCEAPLALQLQPQASLHLKEKVICRACGTGNP
Sbjct: 241 RLPPPEGAQMGLCAECRSLVPMNTPICVVCEAPLALQLQPQASLHLKEKVICRACGTGNP 300

Query: 301 AHLRYCVTCEGALPSSQESMCSGDKAPPPPTQKGGTISCYRCGRWNLWEASFCGWCGAML 360
           AHLRYCVTCEGALPSSQESMCSGDKAPPPPTQKGGTISCYRCGRWNLWEASFCGWCGAML
Sbjct: 301 AHLRYCVTCEGALPSSQESMCSGDKAPPPPTQKGGTISCYRCGRWNLWEASFCGWCGAML 360

Query: 361 GIPAGCSVCPKCGASNHLSARFCGSCGICVKSLVKLSLDRSLALAAEEPRPFSESLNIPL 420
           GIPAGCSVCPKCGASNHLSARFCGSCGICVKSLVKLSLDRSLALAAEEPRPFSESLNIPL
Sbjct: 361 GIPAGCSVCPKCGASNHLSARFCGSCGICVKSLVKLSLDRSLALAAEEPRPFSESLNIPL 420

Query: 421 PRSDVGTKRDIGTQTVGLFYPSGKLLAKKEQELASQKQRQEKMSDHKPLLTAISPGRGYW 480
           PRSDVGTKRDIGTQTVGLFYPSGKLLAKKEQELASQKQRQEKMSDHKPLLTAISPGRGYW
Sbjct: 421 PRSDVGTKRDIGTQTVGLFYPSGKLLAKKEQELASQKQRQEKMSDHKPLLTAISPGRGYW 480

Query: 481 RRQLDHISAHLRCYAQNNPEFRALIAEPRMGKLISATVHEDGCEVSIRLNYSQVSNKNLY 540
           RRQLDHISAHLRCYAQNNPEFRALIAEPRMGKLISATVHEDGCEVSIRLNYSQVSNKNLY
Sbjct: 481 RRQLDHISAHLRCYAQNNPEFRALIAEPRMGKLISATVHEDGCEVSIRLNYSQVSNKNLY 540

Query: 541 LNKAVNFSDHLLSSAAEGDGGLCGSRSSWVSDYSQSTSDTIEKIKRIKNFKTKTFQEKKE 600
           LNKAVNFSDHLLSSAAEGDGGLCGSRSSWVSDYSQSTSDTIEKIKRIKNFKTKTFQEKKE
Sbjct: 541 LNKAVNFSDHLLSSAAEGDGGLCGSRSSWVSDYSQSTSDTIEKIKRIKNFKTKTFQEKKE 600

Query: 601 QLIPENRLLLKEVGPTGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVL 660
           QLIPENRLLLKEVGPTGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVL
Sbjct: 601 QLIPENRLLLKEVGPTGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVL 660

Query: 661 VQRGADIDQQWGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNT 720
           VQRGADIDQQWGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNT
Sbjct: 661 VQRGADIDQQWGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNT 720

Query: 721 GDDLVTSLFAAKFGQGLEDQLAQTRSLSLDDC 752
           GDDLVTSLFAAKFGQGLEDQLAQTRSLSLDDC
Sbjct: 721 GDDLVTSLFAAKFGQGLEDQLAQTRSLSLDDC 752


>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
          Length = 1429

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 32/109 (29%), Positives = 54/109 (49%), Gaps = 5/109 (4%)

Query: 615 PTGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPL 674
           P  +G  SV+  L+D GA+ + CD+D    + VA    H + + +L++ GAD+D      
Sbjct: 722 PASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNG 781

Query: 675 RNTALHEATLLGLAGRESTA-TLLGCNASIQKKNAGGQTAYDLALNTGD 722
           R   L  A++    G  S   TLL   A++   ++ G+T   +A   G+
Sbjct: 782 RTPLLAAASM----GHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGN 826



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 36/112 (32%), Positives = 50/112 (44%), Gaps = 11/112 (9%)

Query: 620 RVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTAL 679
           R   I  LLD GA  N CD + R ++  A  +   + + +LV RGAD++ +         
Sbjct: 524 REDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIE-------DA 576

Query: 680 HEATLLGLAGRES----TATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTS 727
           H  T L LA R+        L+GC A+I   +  G TA   A   G   V S
Sbjct: 577 HGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVS 628



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 8/95 (8%)

Query: 618  EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
            EG + V++ LL+ GADPN  D+  R  + VA  N H + I +L + GA       P    
Sbjct: 1055 EGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGCSPSPVH 1114

Query: 678  ALHEATLLGLAGRESTATLLGCNASIQKKNAGGQT 712
             + +  L  L+ +  + T+        K N+ G T
Sbjct: 1115 TMEQKPLQSLSSKVQSLTI--------KSNSSGST 1141



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 6/130 (4%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           EG   + E L+++GA  N  D D R    +A    H++ + +L++  ++IDQ+    RN 
Sbjct: 857 EGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRN- 915

Query: 678 ALHEATLLGLAGRESTATLLGCNASIQKKNAGGQ-TAYDLALNTGDDLVTSLFAAKFGQG 736
           AL  A L G   R+    L    A +  K+A G+ T Y LAL   + L  + +  + G  
Sbjct: 916 ALRVAALEG--HRDIVELLFSHGADVNCKDADGRPTLYILALE--NQLTMAEYFLENGAN 971

Query: 737 LEDQLAQTRS 746
           +E   A+ R+
Sbjct: 972 VEASDAEGRT 981



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G   V+  LL  G   +C D D+R  +  A    H + +  L+Q GA++++     R TA
Sbjct: 622 GHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGR-TA 680

Query: 679 LHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLA 717
           L  A  +G   RE    LL   A +  ++  G+TA  +A
Sbjct: 681 LIAAAYMG--HREIVEHLLDHGAEVNHEDVDGRTALSVA 717



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 34/137 (24%), Positives = 56/137 (40%), Gaps = 12/137 (8%)

Query: 601  QLIPENRLLLKEVGPTG---------EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMN 651
            Q++ EN+  + + G  G         EG   ++E L   GAD NC D D RP + +  + 
Sbjct: 897  QILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALE 956

Query: 652  KHHEAIPVLVQRGADIDQQWGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQ 711
                     ++ GA+++      R TALH +   G    E    L+  +A +   +   +
Sbjct: 957  NQLTMAEYFLENGANVEASDAEGR-TALHVSCWQG--HMEMVQVLIAYHADVNAADNEKR 1013

Query: 712  TAYDLALNTGDDLVTSL 728
            +A   A   G   V  L
Sbjct: 1014 SALQSAAWQGHVKVVQL 1030



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 19/55 (34%), Positives = 30/55 (54%), Gaps = 5/55 (9%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVM-----NKHHEAIPVLVQRGADID 668
           G   ++E LLD GA+ N  D D R  ++VA +       H   + +L+ RGA++D
Sbjct: 688 GHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVD 742



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 3/104 (2%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           +G   V+  L+  GA+ N  D+D    +  A    H E +  L+  G  +D      R T
Sbjct: 588 QGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSR-T 646

Query: 678 ALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTG 721
           AL  A   G    +    LL   A + K +  G+TA   A   G
Sbjct: 647 ALRAAAWGG--HEDIVLNLLQHGAEVNKADNEGRTALIAAAYMG 688



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 12/115 (10%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ----WGPL 674
           G + V+  L+  GAD    D      +T+A    H + +  L+  GA+I+      W  L
Sbjct: 556 GSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTAL 615

Query: 675 RNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTG-DDLVTSL 728
           R+ A    T       E  + LL     +   +A  +TA   A   G +D+V +L
Sbjct: 616 RSAAWGGHT-------EVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNL 663


>gi|18252778 ankyrin repeat and SOCS box-containing protein 2 [Homo
           sapiens]
          Length = 587

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 12/141 (8%)

Query: 616 TGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ----W 671
           T  G +  +  LL  GA+P+  ++     +  A   K+ EA+ +LVQ  AD + +    W
Sbjct: 132 TCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGW 191

Query: 672 GPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAA 731
                TALHE+  +     E    L+   A ++ KNA G T   +A  +G  L    F A
Sbjct: 192 -----TALHES--VSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSG-QLEALRFLA 243

Query: 732 KFGQGLEDQLAQTRSLSLDDC 752
           K+G  +  Q +   S   + C
Sbjct: 244 KYGADINTQASDNASALYEAC 264



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 7/117 (5%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQ--QWGPLRN 676
           G++  +  L   GAD N    DN   +  A  N+H E +  L+ +GAD ++  + G L  
Sbjct: 234 GQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLL-- 291

Query: 677 TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAAKF 733
             LH A+  G         LL   +  + + +G    +  A    D+++ +L +A+F
Sbjct: 292 -PLHIASKKG--NYRIVQMLLPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARF 345


>gi|157743284 ankyrin repeat domain 52 [Homo sapiens]
          Length = 1076

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 36/110 (32%), Positives = 51/110 (46%), Gaps = 9/110 (8%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADI---DQQWGPLR 675
           G +  +  LL++GA  N CD+  R  +  A    H E + +LV RGAD+   D++   L 
Sbjct: 151 GHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLL 210

Query: 676 NTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLV 725
           +TA     +      E    LL   A I + NA G TA  +A   G D V
Sbjct: 211 HTAAASGQI------EVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAV 254



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 8/111 (7%)

Query: 619 GRVSVIEQLLDEG--AD-PNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLR 675
           G    +  L+D G  AD  +  D   +  + +A+MN H + + +L+++G+  D     LR
Sbjct: 663 GHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADA--ADLR 720

Query: 676 -NTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLV 725
             TALH   + G    +  A LL  +A +  ++  G+T   LA   G   V
Sbjct: 721 GRTALHRGAVTGC--EDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAV 769



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 5/65 (7%)

Query: 624 IEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADID--QQWGPLRNTALHE 681
           +E L++ GAD N   ++ +  + +A ++       +L+Q G++ID   ++G   NT LH 
Sbjct: 289 LELLVNNGADVNYQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKFG---NTPLHV 345

Query: 682 ATLLG 686
           A   G
Sbjct: 346 AARYG 350


>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
           polymerase 2 [Homo sapiens]
          Length = 1166

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 47/140 (33%), Positives = 62/140 (44%), Gaps = 11/140 (7%)

Query: 617 GEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGA--DIDQQWGPL 674
           G  RVSV+E LL  GAD +  D+     +  A    H+E   +LV+ GA  ++   W   
Sbjct: 535 GYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLW--- 591

Query: 675 RNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLF---AA 731
           + T LHEA   G    E    LL   A   KKN  G T  DL +  GD  +  L    AA
Sbjct: 592 KFTPLHEAAAKG--KYEICKLLLQHGADPTKKNRDGNTPLDL-VKDGDTDIQDLLRGDAA 648

Query: 732 KFGQGLEDQLAQTRSLSLDD 751
                 +  LA+ + LS  D
Sbjct: 649 LLDAAKKGCLARVKKLSSPD 668



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 7/103 (6%)

Query: 617 GEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADID--QQWGPL 674
           G GR  V+E LL  GA+    D+     +  A    H E + +L++ GAD +    W   
Sbjct: 67  GFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNW--- 123

Query: 675 RNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLA 717
             T LHEA + G    +    LL   A    +N  G+TA DLA
Sbjct: 124 NYTPLHEAAIKGKI--DVCIVLLQHGAEPTIRNTDGRTALDLA 164



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 7/103 (6%)

Query: 617 GEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ--WGPL 674
           G  RV +++ LL  GAD +  D+ +   +  A    H+E   +LV+ GA ++    W   
Sbjct: 220 GYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLW--- 276

Query: 675 RNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLA 717
           + T LHEA        E  + LL   A     N   ++A DLA
Sbjct: 277 QFTPLHEAASKNRV--EVCSLLLSYGADPTLLNCHNKSAIDLA 317



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 7/80 (8%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G   V+  LL  GADPN  D  N   +  A +    +   VL+Q GA+       +RNT 
Sbjct: 102 GHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAE-----PTIRNT- 155

Query: 679 LHEATLLGLAGRESTATLLG 698
               T L LA   + A L G
Sbjct: 156 -DGRTALDLADPSAKAVLTG 174


>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
          Length = 300

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 17/121 (14%)

Query: 611 KEVGPTGE--------------GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEA 656
           + +GPTG+                V  ++QLL++GADP   D+  R  +  A  N + + 
Sbjct: 99  RRLGPTGKEVHALKRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQI 158

Query: 657 IPVLVQRGADIDQQWGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDL 716
           + +L+  GAD +Q+ G L NT LH A            TLL   A +   +  G+T   L
Sbjct: 159 VQLLLDHGADPNQRDG-LGNTPLHLAACTNHV--PVITTLLRGGARVDALDRAGRTPLHL 215

Query: 717 A 717
           A
Sbjct: 216 A 216


>gi|55742857 ankyrin repeat domain 6 [Homo sapiens]
          Length = 722

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           +G + V++ LL  G D +  D+ ++  +  A +  + E I  L+  G  +D+Q     NT
Sbjct: 52  KGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQ-DKDGNT 110

Query: 678 ALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLA 717
           ALHEA+  G +  +S   L+   A++  KN  G TA  LA
Sbjct: 111 ALHEASWHGFS--QSAKLLVKAGANVLAKNKAGNTALHLA 148


>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
          Length = 1430

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 33/106 (31%), Positives = 46/106 (43%), Gaps = 3/106 (2%)

Query: 616 TGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLR 675
           +  G   ++E L + GAD N CD+D    + +AV     E I  L+ +G  +D Q     
Sbjct: 519 SARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQ-DRHG 577

Query: 676 NTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTG 721
           NT LH A   G         L   N ++   N  G+T   LA N G
Sbjct: 578 NTPLHVACKDG--NMPIVVALCEANCNLDISNKYGRTPLHLAANNG 621


>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
           polymerase [Homo sapiens]
          Length = 1327

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 38/110 (34%), Positives = 49/110 (44%), Gaps = 7/110 (6%)

Query: 617 GEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADID--QQWGPL 674
           G  RVSV+E LL  GAD +  D+     +  A    H+E   +LV+ GA ++    W   
Sbjct: 693 GYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLW--- 749

Query: 675 RNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDL 724
           + T LHEA   G    E    LL   A   KKN  G T  DL      D+
Sbjct: 750 KFTPLHEAAAKG--KYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDI 797



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 7/103 (6%)

Query: 617 GEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADID--QQWGPL 674
           G GR  V+E LL  GA+ +  D+     +  A    H E + +L+ +GAD +    W   
Sbjct: 225 GFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNW--- 281

Query: 675 RNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLA 717
             T LHEA + G    +    LL   A    +N  G++A DLA
Sbjct: 282 NYTPLHEAAIKGKI--DVCIVLLQHGADPNIRNTDGKSALDLA 322



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 37/117 (31%), Positives = 50/117 (42%), Gaps = 9/117 (7%)

Query: 617 GEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADID--QQWGPL 674
           G   + V E LL+ GAD N  D+     +  A    H +   +L++    ++   +W   
Sbjct: 846 GYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWA-- 903

Query: 675 RNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAA 731
             T LHEA   G    +  A LL   A    KN  GQT  DLA  T DD+   L  A
Sbjct: 904 -FTPLHEAAQKGRT--QLCALLLAHGADPTMKNQEGQTPLDLA--TADDIRALLIDA 955



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 7/103 (6%)

Query: 617 GEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ--WGPL 674
           G  RV +++ LL  GAD +  D+     +  A    H+E   +L++ GA ++    W   
Sbjct: 378 GYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLW--- 434

Query: 675 RNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLA 717
           + T LHEA        E  + LL   A     N  G++A D+A
Sbjct: 435 QFTPLHEAASKNRV--EVCSLLLSHGADPTLVNCHGKSAVDMA 475



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 7/80 (8%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G   V+  LL +GADPN  D  N   +  A +    +   VL+Q GAD +     +RNT 
Sbjct: 260 GHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPN-----IRNTD 314

Query: 679 LHEATLLGLAGRESTATLLG 698
              A  L LA   + A L G
Sbjct: 315 GKSA--LDLADPSAKAVLTG 332



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 620 RVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTAL 679
           R  V E LL +GA+ N  ++D    + VA    H++ + VL + GA ++     L  TAL
Sbjct: 537 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMN-ALDTLGQTAL 595

Query: 680 HEATLLG 686
           H A L G
Sbjct: 596 HRAALAG 602


>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
          Length = 1050

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           +G   V++ LLD  A PN  D      +  A    HHE + +L+Q GA I+       NT
Sbjct: 787 QGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINAS-NNKGNT 845

Query: 678 ALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLA 717
           ALHEA +           L G  AS+Q  N   +TA D A
Sbjct: 846 ALHEAVIEKHVFVVELLLLHG--ASVQVLNKRQRTAVDCA 883


>gi|38327522 cardiac ankyrin repeat protein [Homo sapiens]
          Length = 319

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 3/141 (2%)

Query: 581 IEKIKRIKNFKTKTFQEKKEQLIPENRLLLKEVGPTGEGRVSVIEQLLDEGADPNCCDED 640
           ++K K+ +  K    +E + ++I E   +   +    E ++ V+E+ L +  +P+ CDE 
Sbjct: 93  LKKRKKYRKTKVPVVKEPEPEIITEPVDVPTFLKAALENKLPVVEKFLSDKNNPDVCDEY 152

Query: 641 NRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTALHEATLLGLAGRESTATLLGCN 700
            R  +  A +  H   +  L++ GA I+ +   L +TA+H A+  G    +    LL   
Sbjct: 153 KRTALHRACLEGHLAIVEKLMEAGAQIEFR-DMLESTAIHWASRGG--NLDVLKLLLNKG 209

Query: 701 ASIQKKNAGGQTAYDLALNTG 721
           A I  ++    TA  +A+ TG
Sbjct: 210 AKISARDKLLSTALHVAVRTG 230



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 3/101 (2%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G + V++ LL++GA  +  D+     + VAV   H+E    L+   AD++ +     +T 
Sbjct: 197 GNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAK-DREGDTP 255

Query: 679 LHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALN 719
           LH+A  L          + G + +I  KN  G+T  DL L+
Sbjct: 256 LHDAVRLNRYKMIRLLIMYGADLNI--KNCAGKTPMDLVLH 294


>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
           sapiens]
          Length = 1771

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 37/129 (28%), Positives = 55/129 (42%), Gaps = 4/129 (3%)

Query: 617 GEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRN 676
           G G   ++  LL  GA  NC D+     +  A    H E +  L+  GAD+DQ+ G    
Sbjct: 146 GRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLAMGADVDQE-GANSM 204

Query: 677 TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTG-DDLVTSLFAAKFGQ 735
           TAL  A   G    +S   +L  N ++   +  G TA  +A   G  ++V  L  A    
Sbjct: 205 TALIVAVKGGYT--QSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYV 262

Query: 736 GLEDQLAQT 744
            + D+   T
Sbjct: 263 NIPDRSGDT 271



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 3/95 (3%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           EG   +++ LLD G   N  D     V+  AV   H E +  L+Q+ ADID + G    T
Sbjct: 246 EGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIR-GQDNKT 304

Query: 678 ALHEATLLGLAGRESTATLLGCNASIQKKNAGGQT 712
           AL+ A   G A       +L CN   +     G+T
Sbjct: 305 ALYWAVEKGNA--TMVRDILQCNPDTEICTKDGET 337


>gi|103471993 huntingtin interacting protein 14 [Homo sapiens]
          Length = 632

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 36/136 (26%), Positives = 54/136 (39%), Gaps = 36/136 (26%)

Query: 616 TGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQ------ 669
           T +G +S++ QL+  GADP+  D +    I +A    H   +  L+ +G D+D       
Sbjct: 132 TRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGM 191

Query: 670 ---QWGPLR-------------------------NTALHEATLLGLAGRESTATLLGCNA 701
               W   R                         NTALH A L G       + LL   A
Sbjct: 192 TPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAG--NTTVISLLLEAGA 249

Query: 702 SIQKKNAGGQTAYDLA 717
           ++  +N  G++A DLA
Sbjct: 250 NVDAQNIKGESALDLA 265



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 29/113 (25%), Positives = 51/113 (45%), Gaps = 3/113 (2%)

Query: 626 QLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTALHEATLL 685
           +L++ G D    D++N  ++  A +N   + +   + +GA +DQ  G L +T LH AT  
Sbjct: 75  ELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQ 134

Query: 686 GLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAAKFGQGLE 738
           G           G + S+   +  G +   LA   G   + +   AK GQ ++
Sbjct: 135 GHLSMVVQLMKYGADPSL--IDGEGCSCIHLAAQFGHTSIVAYLIAK-GQDVD 184


>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1363

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 36/104 (34%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGA--DIDQQWGPLRN 676
           GRV V+  LLD     N CD  NR  +  AV  +      +L++RGA  +I   +G   N
Sbjct: 178 GRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYG---N 234

Query: 677 TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNT 720
           TALH A      G      LL  +A+I+  N  G T    A+N+
Sbjct: 235 TALHYAVY--NEGTSLAERLLSHHANIEALNKEGNTPLLFAINS 276


>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1366

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 36/104 (34%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGA--DIDQQWGPLRN 676
           GRV V+  LLD     N CD  NR  +  AV  +      +L++RGA  +I   +G   N
Sbjct: 207 GRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYG---N 263

Query: 677 TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNT 720
           TALH A      G      LL  +A+I+  N  G T    A+N+
Sbjct: 264 TALHYAVY--NEGTSLAERLLSHHANIEALNKEGNTPLLFAINS 305


>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1139

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 36/104 (34%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGA--DIDQQWGPLRN 676
           GRV V+  LLD     N CD  NR  +  AV  +      +L++RGA  +I   +G   N
Sbjct: 207 GRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYG---N 263

Query: 677 TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNT 720
           TALH A      G      LL  +A+I+  N  G T    A+N+
Sbjct: 264 TALHYAVY--NEGTSLAERLLSHHANIEALNKEGNTPLLFAINS 305


>gi|239757617 PREDICTED: similar to hCG1793014 [Homo sapiens]
          Length = 251

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 7/116 (6%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGAD--IDQQWGPLRN 676
           GR  V+  L+D     +  D +NR  +  AV  +      +L+  GAD  I   +G   N
Sbjct: 83  GRAEVVTLLVDRKCQLDILDGENRTTLMKAVQCQREVCANILIDSGADPNIVDVYG---N 139

Query: 677 TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAAK 732
           TA+H A L+G       A LL C A I+ KN  G T   L +    + +      K
Sbjct: 140 TAVHYA-LIG-ENLSVVAKLLSCGADIEVKNKTGHTPLLLVMRKRSEQIVEFLLTK 193



 Score = 33.5 bits (75), Expect = 0.75
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 7/104 (6%)

Query: 627 LLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTALHEATLLG 686
           L+D GADPN  D      +  A++ ++   +  L+  GADI+     ++N   H   LL 
Sbjct: 124 LIDSGADPNIVDVYGNTAVHYALIGENLSVVAKLLSCGADIE-----VKNKTGHTPLLLV 178

Query: 687 LAGRESTAT--LLGCNASIQKKNAGGQTAYDLALNTGDDLVTSL 728
           +  R       LL  NA+    +    TA  LA+  G   +  +
Sbjct: 179 MRKRSEQIVEFLLTKNANANAVDKFKCTALMLAMCHGSSEIVGM 222


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 12/106 (11%)

Query: 619 GRVSVIEQLLD--------EGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ 670
           GR+ V + LL+        EG   + CD +    + +A  N H E I  L++ G +I++Q
Sbjct: 77  GRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQ 136

Query: 671 WGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDL 716
                 TALHEA L G    E    LL     +  +N   QTA D+
Sbjct: 137 --TKTGTALHEAALYGKT--EVVRLLLEGGVDVNIRNTYNQTALDI 178


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 12/106 (11%)

Query: 619 GRVSVIEQLLD--------EGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ 670
           GR+ V + LL+        EG   + CD +    + +A  N H E I  L++ G +I++Q
Sbjct: 159 GRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQ 218

Query: 671 WGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDL 716
                 TALHEA L G    E    LL     +  +N   QTA D+
Sbjct: 219 --TKTGTALHEAALYGKT--EVVRLLLEGGVDVNIRNTYNQTALDI 260


>gi|41327752 diabetes related ankyrin repeat protein [Homo sapiens]
          Length = 305

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 3/99 (3%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G + +++QLL++GA  N  D+     + VAV  +H + +  L++ GA ++ Q     +TA
Sbjct: 188 GHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQ-DKEGDTA 246

Query: 679 LHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLA 717
           LHEA   G    ++   LL   A +  +NA   T   LA
Sbjct: 247 LHEAVRHG--SYKAMKLLLLYGAELGVRNAASVTPVQLA 283



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 7/91 (7%)

Query: 585 KRIKNFKTKTFQEKKEQLI-PENRLLLKEVG------PTGEGRVSVIEQLLDEGADPNCC 637
           +R K  + +    K E L+ P+++  ++ VG         E +  +I++ L +G DPN  
Sbjct: 81  RRKKRLRHRVPPRKPEPLVKPQSQAQVEPVGLEMFLKAAAENQEYLIDKYLTDGGDPNAH 140

Query: 638 DEDNRPVITVAVMNKHHEAIPVLVQRGADID 668
           D+ +R  +  A +  H + +  L+  GA +D
Sbjct: 141 DKLHRTALHWACLKGHSQLVNKLLVAGATVD 171


>gi|67906195 ankyrin repeat and sterile alpha motif domain
           containing 6 [Homo sapiens]
          Length = 871

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/158 (27%), Positives = 72/158 (45%), Gaps = 18/158 (11%)

Query: 579 DTIEKIKRIKNFKTKTFQEKKEQLIPENRLLLKEVGPTGEGRVSVIEQLLDEGADP---N 635
           D ++ +  +   + KT +EK+    P+    LK       G   +++++ DE  DP   N
Sbjct: 272 DLVDYLDPLTTVRPKTDEEKRR---PDIFHALKM------GNFQLVKEIADE--DPSHVN 320

Query: 636 CCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTALHEATLLGLAGRESTAT 695
             + D    + +A +      + +LV+R AD+D+Q      TAL +AT  G   +E    
Sbjct: 321 LVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHG--NKEIVKY 378

Query: 696 LLGCNASIQKKNAGGQTAYDLA--LNTGDDLVTSLFAA 731
           LL   A +  +   G TA+DL   LN  D  +  L A+
Sbjct: 379 LLNQGADVTLRAKNGYTAFDLVMLLNDPDTELVRLLAS 416



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 20/50 (40%), Positives = 27/50 (54%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADID 668
           G VSV   LLD GAD N  +     V+TVA    H   + +L++ GA +D
Sbjct: 122 GHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVD 171


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 12/106 (11%)

Query: 619 GRVSVIEQLLD--------EGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ 670
           GRV V++ LL         E    +  D +    + +A  N H + I +L+Q G DI++Q
Sbjct: 159 GRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQ 218

Query: 671 WGPLRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDL 716
                 TALHEA L G    E    LL    +   +N   QTA D+
Sbjct: 219 --TKSGTALHEAALCGKT--EVVRLLLDSGINAHVRNTYSQTALDI 260


>gi|4502753 cyclin-dependent kinase inhibitor 2D [Homo sapiens]
          Length = 166

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 5/111 (4%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G  ++  +LL +GA PN  D      +  A      + + VLV+ GAD++   G    T 
Sbjct: 52  GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDG----TG 107

Query: 679 LHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTG-DDLVTSL 728
                L    G  +  + L   + + +++A G T  +LAL  G  DLV  L
Sbjct: 108 ALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 158


>gi|17981702 cyclin-dependent kinase inhibitor 2D [Homo sapiens]
          Length = 166

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 5/111 (4%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G  ++  +LL +GA PN  D      +  A      + + VLV+ GAD++   G    T 
Sbjct: 52  GSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDG----TG 107

Query: 679 LHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTG-DDLVTSL 728
                L    G  +  + L   + + +++A G T  +LAL  G  DLV  L
Sbjct: 108 ALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDIL 158


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 4/91 (4%)

Query: 620 RVSVIEQLLD---EGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRN 676
           R   +E+ LD    G D N C+++    + +A    H E +  L+QR A++D       N
Sbjct: 50  RAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAA-TKKGN 108

Query: 677 TALHEATLLGLAGRESTATLLGCNASIQKKN 707
           TALH A+L G A         G N + Q +N
Sbjct: 109 TALHIASLAGQAEVVKVLVTNGANVNAQSQN 139



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 3/109 (2%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G V+++ QL+  GA PN  +      + +A  +   E +  LVQ GA ++ +      T 
Sbjct: 444 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAK-AKDDQTP 502

Query: 679 LHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTS 727
           LH +  LG A  +    LL   AS       G T   L+   G + V +
Sbjct: 503 LHISARLGKA--DIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAA 549



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 11/115 (9%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           EG V V+ +LL   A+ +   +     + +A +    E + VLV  GA+++ Q       
Sbjct: 84  EGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ------- 136

Query: 678 ALHEATLLGLAGRES----TATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSL 728
           + +  T L +A +E+       LL   AS       G T   +AL  G D V SL
Sbjct: 137 SQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSL 191



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 7/111 (6%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           E  + V++ LLD GA  +   ED    + VA+   H + + +L++         G +R  
Sbjct: 150 ENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTK-----GKVRLP 204

Query: 678 ALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSL 728
           ALH A        ++ A LL  + +   ++  G T   +A + G+  V +L
Sbjct: 205 ALHIAARKD--DTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATL 253



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 38/166 (22%), Positives = 62/166 (37%), Gaps = 24/166 (14%)

Query: 567 SSWVSDYSQSTSDTIEKIKRIKNFKTKTFQEKKEQLIPENRLLLKEVGPTGEGRVS---- 622
           ++++ D+  S S T +K      F       K  +L   N LL K   P   G+      
Sbjct: 548 AAFLLDHGASLSITTKK-----GFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPL 602

Query: 623 ----------VIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWG 672
                     V   LLD+GA P+   ++    + +A      +    L++ GAD +    
Sbjct: 603 HVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN---- 658

Query: 673 PLRNTALHEATLLGLAGR-ESTATLLGCNASIQKKNAGGQTAYDLA 717
            +    +    L    G  +  + LLG NA++   N  G T   LA
Sbjct: 659 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLA 704



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 12/49 (24%), Positives = 23/49 (46%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADI 667
           G+  +++QLL +GA PN         + ++    H +    L+  GA +
Sbjct: 510 GKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASL 558



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 3/103 (2%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G   V + LLD+ A+PN    +    + +A      + + +L++ GA I Q       T 
Sbjct: 378 GHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASI-QAVTESGLTP 436

Query: 679 LHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTG 721
           +H A  +G       + L+   AS    N  G+TA  +A  +G
Sbjct: 437 IHVAAFMGHV--NIVSQLMHHGASPNTTNVRGETALHMAARSG 477



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 27/104 (25%), Positives = 40/104 (38%), Gaps = 3/104 (2%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           EG V ++  LL   A+ N  ++     + +A          VLV +GA +D Q   +  T
Sbjct: 674 EGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQ-TKMGYT 732

Query: 678 ALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTG 721
            LH     G    +    LL  +A +  K   G T    A   G
Sbjct: 733 PLHVGCHYG--NIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQG 774


>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 2542

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 4/96 (4%)

Query: 619  GRVSVIEQLLDEGADPNCCDEDNRPV--ITVAVMNKHHEAIPVLVQRGADIDQQWGPLRN 676
            G V++I+ LL+ GA+ N        +  + +A MN H  A+ +L+  G+DI+ Q    RN
Sbjct: 1166 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN 1225

Query: 677  TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQT 712
            TAL  A   G A  E  + LL   A+++ +   G T
Sbjct: 1226 TALTLACFQGRA--EVVSLLLDRKANVEHRAKTGLT 1259



 Score = 37.7 bits (86), Expect = 0.040
 Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 17/128 (13%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADI----DQQWGP 673
           +G V V   LLD GA  N   +     +T+A    H E   +L++RGA++    D+ + P
Sbjct: 415 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTP 474

Query: 674 LRNTALHEATLLGLAGRESTATLL---GCNASIQKKNAGGQTAYDLALNTGDDLVTSLFA 730
           L   A          G E    LL   G N + Q +    +TA  LA   G   V   F 
Sbjct: 475 LMEAARE--------GHEEMVALLLAQGANINAQTEET-QETALTLACCGGFSEVAD-FL 524

Query: 731 AKFGQGLE 738
            K G  +E
Sbjct: 525 IKAGADIE 532



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 16/53 (30%), Positives = 28/53 (52%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ 670
           EG + +++ LL  GA+ +         +T A  N H +   VL+Q GAD++ +
Sbjct: 545 EGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHE 597



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 12/118 (10%)

Query: 619  GRVSVIEQLLDEGADPNCCDEDNRPV-ITVAVMNKHHEAIPVLVQRGADIDQQ----WGP 673
            G V V+E LLD+G D     E  +   +++A      E + +L+ RGA+ + +    + P
Sbjct: 1099 GHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTP 1158

Query: 674  LRNTA----LHEATLLGLAGRE---STATLLGCNASIQKKNAGGQTAYDLALNTGDDL 724
            L   A    ++   +L  AG E    T + LG +  +     G   A  L L+ G D+
Sbjct: 1159 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 1216



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 619  GRVSVIEQLLDEGADPNC--CDEDNRPVITVAVMNKHHEAIPVLVQRGADID 668
            G   V   LLD+GAD N           +T+A    H++   +L+ RGA ID
Sbjct: 1268 GYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHID 1319


>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
          Length = 2617

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/96 (33%), Positives = 50/96 (52%), Gaps = 4/96 (4%)

Query: 619  GRVSVIEQLLDEGADPNCCDEDNRPV--ITVAVMNKHHEAIPVLVQRGADIDQQWGPLRN 676
            G V++I+ LL+ GA+ N        +  + +A MN H  A+ +L+  G+DI+ Q    RN
Sbjct: 1166 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRN 1225

Query: 677  TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQT 712
            TAL  A   G A  E  + LL   A+++ +   G T
Sbjct: 1226 TALTLACFQGRA--EVVSLLLDRKANVEHRAKTGLT 1259



 Score = 37.7 bits (86), Expect = 0.040
 Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 17/128 (13%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADI----DQQWGP 673
           +G V V   LLD GA  N   +     +T+A    H E   +L++RGA++    D+ + P
Sbjct: 415 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTP 474

Query: 674 LRNTALHEATLLGLAGRESTATLL---GCNASIQKKNAGGQTAYDLALNTGDDLVTSLFA 730
           L   A          G E    LL   G N + Q +    +TA  LA   G   V   F 
Sbjct: 475 LMEAARE--------GHEEMVALLLAQGANINAQTEET-QETALTLACCGGFSEVAD-FL 524

Query: 731 AKFGQGLE 738
            K G  +E
Sbjct: 525 IKAGADIE 532



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 16/53 (30%), Positives = 28/53 (52%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQ 670
           EG + +++ LL  GA+ +         +T A  N H +   VL+Q GAD++ +
Sbjct: 545 EGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHE 597



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 12/118 (10%)

Query: 619  GRVSVIEQLLDEGADPNCCDEDNRPV-ITVAVMNKHHEAIPVLVQRGADIDQQ----WGP 673
            G V V+E LLD+G D     E  +   +++A      E + +L+ RGA+ + +    + P
Sbjct: 1099 GHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTP 1158

Query: 674  LRNTA----LHEATLLGLAGRE---STATLLGCNASIQKKNAGGQTAYDLALNTGDDL 724
            L   A    ++   +L  AG E    T + LG +  +     G   A  L L+ G D+
Sbjct: 1159 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 1216



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 619  GRVSVIEQLLDEGADPNC--CDEDNRPVITVAVMNKHHEAIPVLVQRGADID 668
            G   V   LLD+GAD N           +T+A    H++   +L+ RGA ID
Sbjct: 1268 GYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHID 1319


>gi|223634006 hypothetical protein LOC441869 [Homo sapiens]
          Length = 399

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 7/81 (8%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           GR   IE LL  GADP   D   R  +  A    H  A+ +LV +GA++D +   L  T 
Sbjct: 247 GRSQDIEVLLGHGADPGIRDRHGRSALHRAAARGHLLAVQLLVTQGAEVDAR-DTLGLTP 305

Query: 679 LHEATLLGLAGRESTATLLGC 699
           LH A+      RE    + GC
Sbjct: 306 LHHAS------REGHVEVAGC 320



 Score = 37.0 bits (84), Expect = 0.067
 Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 3/118 (2%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTA 678
           G   ++ QLL +GA     D   R  + +AV+  H   + +L+QRGA +         TA
Sbjct: 52  GPAGLVTQLLRQGASVEERDHAGRTPLHLAVLRGHAPLVRLLLQRGAPVGAV-DRAGRTA 110

Query: 679 LHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGDDLVTSLFAAKFGQG 736
           LHEA   G +       LL   AS   ++  G T    A   G  L+ +      G G
Sbjct: 111 LHEAAWHGHS--RVAELLLQRGASAAARSGTGLTPLHWAAALGHTLLAARLLEAPGPG 166


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 6/97 (6%)

Query: 619  GRVSVIEQLLDEGADPNCCDEDNRPV--ITVAVMNKHHEAIPVLVQRGADIDQQWGPLRN 676
            G V++I+ LL+ GA+ N        +  + +A MN H  A+ +L+  G+DI+ Q    RN
Sbjct: 1194 GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRN 1253

Query: 677  TALHEATLLGLAGR-ESTATLLGCNASIQKKNAGGQT 712
            TAL   TL    GR E  + LL   A+++ +   G T
Sbjct: 1254 TAL---TLACFQGRTEVVSLLLDRKANVEHRAKTGLT 1287



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 39/126 (30%), Positives = 53/126 (42%), Gaps = 13/126 (10%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADI----DQQWGP 673
           +G V V   LLD GA  N   +     +T+A    H E   +L++RGA +    D+ + P
Sbjct: 444 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTP 503

Query: 674 LRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQ-TAYDLALNTGDDLVTSLFAAK 732
           L   A            E  A LLG  A+I  +    Q TA  LA   G  L  + F  K
Sbjct: 504 LMEAARE-------GHEEMVALLLGQGANINAQTEETQETALTLAC-CGGFLEVADFLIK 555

Query: 733 FGQGLE 738
            G  +E
Sbjct: 556 AGADIE 561



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 6/116 (5%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           EG + +++ LL  GA+ +         +T A  N H +   VL+Q GAD++ +    R  
Sbjct: 574 EGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTP 633

Query: 678 ALHEATLLGLAGRESTAT-LLGCNASIQKKNAGG-QTAYDLALNTGDDLVTSLFAA 731
            +  A     AG   T   L+   A++ +  A    T   LA   G   V  L  A
Sbjct: 634 LMKAAR----AGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLA 685



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 12/118 (10%)

Query: 619  GRVSVIEQLLDEGADPNCCDEDNRPV-ITVAVMNKHHEAIPVLVQRGADIDQQ----WGP 673
            G V V+E LLD GAD     E  +   +++A      E + +L+ RGA+ + +    + P
Sbjct: 1127 GHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTP 1186

Query: 674  LRNTA----LHEATLLGLAGRE---STATLLGCNASIQKKNAGGQTAYDLALNTGDDL 724
            L   A    ++   +L  AG E    T + LG +  +     G   A  L L+ G D+
Sbjct: 1187 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 1244



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 4/116 (3%)

Query: 618  EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPL-RN 676
            +GR  V+  LLD  A+     +     +  A    + E   VL+ +GAD++    P  R+
Sbjct: 1262 QGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRD 1321

Query: 677  TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGD-DLVTSLFAA 731
            TAL  A   G    +    L+G  A I  +N  G T   LA N G  D+V  L  A
Sbjct: 1322 TALTIAADKG--HYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQA 1375


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 6/97 (6%)

Query: 619  GRVSVIEQLLDEGADPNCCDEDNRPV--ITVAVMNKHHEAIPVLVQRGADIDQQWGPLRN 676
            G V++I+ LL+ GA+ N        +  + +A MN H  A+ +L+  G+DI+ Q    RN
Sbjct: 943  GYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRN 1002

Query: 677  TALHEATLLGLAGR-ESTATLLGCNASIQKKNAGGQT 712
            TAL   TL    GR E  + LL   A+++ +   G T
Sbjct: 1003 TAL---TLACFQGRTEVVSLLLDRKANVEHRAKTGLT 1036



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 39/126 (30%), Positives = 53/126 (42%), Gaps = 13/126 (10%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADI----DQQWGP 673
           +G V V   LLD GA  N   +     +T+A    H E   +L++RGA +    D+ + P
Sbjct: 444 DGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTP 503

Query: 674 LRNTALHEATLLGLAGRESTATLLGCNASIQKKNAGGQ-TAYDLALNTGDDLVTSLFAAK 732
           L   A            E  A LLG  A+I  +    Q TA  LA   G  L  + F  K
Sbjct: 504 LMEAARE-------GHEEMVALLLGQGANINAQTEETQETALTLAC-CGGFLEVADFLIK 555

Query: 733 FGQGLE 738
            G  +E
Sbjct: 556 AGADIE 561



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 6/116 (5%)

Query: 618 EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNT 677
           EG + +++ LL  GA+ +         +T A  N H +   VL+Q GAD++ +    R  
Sbjct: 574 EGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTP 633

Query: 678 ALHEATLLGLAGRESTAT-LLGCNASIQKKNAGG-QTAYDLALNTGDDLVTSLFAA 731
            +  A     AG   T   L+   A++ +  A    T   LA   G   V  L  A
Sbjct: 634 LMKAAR----AGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLA 685



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 12/118 (10%)

Query: 619 GRVSVIEQLLDEGADPNCCDEDNRPV-ITVAVMNKHHEAIPVLVQRGADIDQQ----WGP 673
           G V V+E LLD GAD     E  +   +++A      E + +L+ RGA+ + +    + P
Sbjct: 876 GHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTP 935

Query: 674 LRNTA----LHEATLLGLAGRE---STATLLGCNASIQKKNAGGQTAYDLALNTGDDL 724
           L   A    ++   +L  AG E    T + LG +  +     G   A  L L+ G D+
Sbjct: 936 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 993



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 4/116 (3%)

Query: 618  EGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPL-RN 676
            +GR  V+  LLD  A+     +     +  A    + E   VL+ +GAD++    P  R+
Sbjct: 1011 QGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRD 1070

Query: 677  TALHEATLLGLAGRESTATLLGCNASIQKKNAGGQTAYDLALNTGD-DLVTSLFAA 731
            TAL  A   G    +    L+G  A I  +N  G T   LA N G  D+V  L  A
Sbjct: 1071 TALTIAADKG--HYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQA 1124


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,583,505
Number of Sequences: 37866
Number of extensions: 1767303
Number of successful extensions: 6326
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 5658
Number of HSP's gapped (non-prelim): 726
length of query: 752
length of database: 18,247,518
effective HSP length: 110
effective length of query: 642
effective length of database: 14,082,258
effective search space: 9040809636
effective search space used: 9040809636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.