Guide to the Human Genome
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Search of human proteins with 14917117

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14917117 keratin 33A [Homo sapiens]
         (404 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14917117 keratin 33A [Homo sapiens]                                810   0.0  
gi|10337581 type I hair keratin 3B [Homo sapiens]                     756   0.0  
gi|14917115 keratin 31 [Homo sapiens]                                 750   0.0  
gi|14917119 keratin 34 [Homo sapiens]                                 697   0.0  
gi|94538345 keratin 35 [Homo sapiens]                                 542   e-154
gi|4504927 keratin 36 [Homo sapiens]                                  534   e-152
gi|116488398 keratin 32 [Homo sapiens]                                528   e-150
gi|15431318 keratin 38 [Homo sapiens]                                 491   e-139
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  476   e-134
gi|55770882 keratin 37 [Homo sapiens]                                 470   e-132
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  455   e-128
gi|15431310 keratin 14 [Homo sapiens]                                 380   e-106
gi|24430192 keratin 16 [Homo sapiens]                                 374   e-103
gi|4557701 keratin 17 [Homo sapiens]                                  373   e-103
gi|24430190 keratin 15 [Homo sapiens]                                 360   e-99 
gi|24234699 keratin 19 [Homo sapiens]                                 360   1e-99
gi|131412225 keratin 13 isoform a [Homo sapiens]                      354   9e-98
gi|131412228 keratin 13 isoform b [Homo sapiens]                      350   1e-96
gi|195972866 keratin 10 [Homo sapiens]                                332   4e-91
gi|4557699 keratin 12 [Homo sapiens]                                  331   6e-91
gi|27894337 keratin 20 [Homo sapiens]                                 313   2e-85
gi|153945736 keratin 27 [Homo sapiens]                                306   3e-83
gi|114431246 keratin 25D [Homo sapiens]                               300   2e-81
gi|192807292 keratin 24 [Homo sapiens]                                297   1e-80
gi|40354195 keratin 18 [Homo sapiens]                                 293   1e-79
gi|4557888 keratin 18 [Homo sapiens]                                  293   1e-79
gi|31559829 keratin 25 [Homo sapiens]                                 291   5e-79
gi|55956899 keratin 9 [Homo sapiens]                                  270   2e-72
gi|27894339 keratin 23 [Homo sapiens]                                 268   6e-72
gi|31559815 keratin 26 [Homo sapiens]                                 267   1e-71

>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  810 bits (2091), Expect = 0.0
 Identities = 404/404 (100%), Positives = 404/404 (100%)

Query: 1   MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60
           MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETM
Sbjct: 1   MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCS 120
           QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCS
Sbjct: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCS 120

Query: 121 KSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQV 180
           KSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQV
Sbjct: 121 KSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQV 180

Query: 181 ESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNR 240
           ESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNR
Sbjct: 181 ESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNR 240

Query: 241 REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300
           REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL
Sbjct: 241 REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300

Query: 301 TESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360
           TESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL
Sbjct: 301 TESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360

Query: 361 ESEDCKLPSNPCATTNACDKSTGPCISNPCGLRARCGPCNTFGY 404
           ESEDCKLPSNPCATTNACDKSTGPCISNPCGLRARCGPCNTFGY
Sbjct: 361 ESEDCKLPSNPCATTNACDKSTGPCISNPCGLRARCGPCNTFGY 404


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  756 bits (1953), Expect = 0.0
 Identities = 379/404 (93%), Positives = 389/404 (96%)

Query: 1   MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60
           M Y+  LPSLSCRTSCSSRPCVPPSCHG TLPGACNIPANVSNCNWFCEGSFNGSEKETM
Sbjct: 1   MPYNFCLPSLSCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCS 120
           QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPL+C SYQSYFKTIEELQQKILCS
Sbjct: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCS 120

Query: 121 KSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQV 180
           KSENARLVVQIDNAKLA+DDFRTKY+TE SLRQLVESDIN LRRILDELTLCRSDLEAQ+
Sbjct: 121 KSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQM 180

Query: 181 ESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNR 240
           ESLKEELL LKQNHEQEVNTLRCQLGDRLNVEVDAAP VDLNQVLNETR+QYEALVETNR
Sbjct: 181 ESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNR 240

Query: 241 REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300
           REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR SLENTL
Sbjct: 241 REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTL 300

Query: 301 TESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360
           TESEARYSSQLSQVQ LITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL
Sbjct: 301 TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360

Query: 361 ESEDCKLPSNPCATTNACDKSTGPCISNPCGLRARCGPCNTFGY 404
           ESEDCKLPSNPCATTNAC+K  G C++NPCG R+RCGPCNTFGY
Sbjct: 361 ESEDCKLPSNPCATTNACEKPIGSCVTNPCGPRSRCGPCNTFGY 404


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  750 bits (1936), Expect = 0.0
 Identities = 378/414 (91%), Positives = 387/414 (93%), Gaps = 12/414 (2%)

Query: 1   MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60
           M Y+  LPSLSCRTSCSSRPCVPPSCH CTLPGACNIPANVSNCNWFCEGSFNGSEKETM
Sbjct: 1   MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCS 120
           QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPL+C SYQSYFKTIEELQQKILC+
Sbjct: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCT 120

Query: 121 KSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQV 180
           KSENARLVVQIDNAKLA+DDFRTKY+TELSLRQLVESDINGLRRILDELTLC+SDLEAQV
Sbjct: 121 KSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQV 180

Query: 181 ESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNR 240
           ESLKEELLCLK NHEQEVNTLRCQLGDRLNVEVDAAPTVDLN+VLNETRSQYEALVETNR
Sbjct: 181 ESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNR 240

Query: 241 REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300
           REVEQWF TQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL
Sbjct: 241 REVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300

Query: 301 TESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360
           TESEARYSSQLSQVQ LITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL
Sbjct: 301 TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360

Query: 361 ESEDCKLPSNPCATTNACDKSTGPCISN------------PCGLRARCGPCNTF 402
           ESEDC LPSNPCATTNAC K  GPC+SN            PC  R RCGPCN+F
Sbjct: 361 ESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSF 414


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  697 bits (1799), Expect = 0.0
 Identities = 351/385 (91%), Positives = 364/385 (94%)

Query: 1   MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60
           MSYSC LPSL CRTSCSSRPCVPPSCHG TLPGACNIPANVSNCNWFCEGSFNGSEKETM
Sbjct: 43  MSYSCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETM 102

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCS 120
           QFLNDRLASYLEKVRQLERDNAELE LI+ERSQQQEPL+C SYQSYFKTIEELQQKILC+
Sbjct: 103 QFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCA 162

Query: 121 KSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQV 180
           K+ENARLVV IDNAKLASDDFR+KY+TE SLR LVESDIN +RRILDELTLC+SDLE+QV
Sbjct: 163 KAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQV 222

Query: 181 ESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNR 240
           ESL+EEL+CLK+NHE+EVNTLR QLGDRLNVEVD APTVDLNQVLNETRSQYEALVE NR
Sbjct: 223 ESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINR 282

Query: 241 REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300
           REVEQWFATQTEELNKQVVSSSEQLQS QAEIIELRRTVNALEIELQAQHNLRDSLENTL
Sbjct: 283 REVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTL 342

Query: 301 TESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360
           TESEA YSSQLSQVQ LITNVESQLAEIR DLERQNQEYQVLLDVRARLECEINTYRSLL
Sbjct: 343 TESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLL 402

Query: 361 ESEDCKLPSNPCATTNACDKSTGPC 385
           ESEDCKLP NPCATTNA   S GPC
Sbjct: 403 ESEDCKLPCNPCATTNASGNSCGPC 427


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  542 bits (1397), Expect = e-154
 Identities = 290/414 (70%), Positives = 327/414 (78%), Gaps = 21/414 (5%)

Query: 2   SYSCGLPSLS--------C-----RTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFC 48
           S SC LPSLS        C     R+S  +  C+P  C    LP      +      WF 
Sbjct: 34  SSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALC----LPAGGFATSYSGGGGWFG 89

Query: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFK 108
           EG   G+EKETMQ LNDRLA YLEKVRQLE++NA LE+ IRE  +QQ P +C  YQSYF+
Sbjct: 90  EGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFR 149

Query: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168
           TIEELQ+K LCSK+ENARLVV+IDNAKLA+DDFRTKYETE+SLRQLVESDINGLRRILD+
Sbjct: 150 TIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDD 209

Query: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228
           LTLC+SDLEAQVESLKEELLCLK+NHE+EVN+LRCQLGDRLNVEVDAAP VDLN+VL E 
Sbjct: 210 LTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEM 269

Query: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R QYE LVE NRR+ E W  TQ+EELN+QVVSSSEQLQS QAEIIELRRTVNALEIELQA
Sbjct: 270 RCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQA 329

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           QH++RD+LE+TL E+EARYSSQL+Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRAR
Sbjct: 330 QHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRAR 389

Query: 349 LECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCI----SNPCGLRARCGP 398
           LECEINTYR LLESED KLP NPCA   +  KS  PC+      P   R  C P
Sbjct: 390 LECEINTYRGLLESEDSKLPCNPCAPDYSPSKSCLPCLPAASCGPSAARTNCSP 443


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  534 bits (1375), Expect = e-152
 Identities = 279/376 (74%), Positives = 317/376 (84%), Gaps = 5/376 (1%)

Query: 4   SCGLPSLSCRTSCSSRPCVPPSCHGCTLPGA-----CNIPANVSNCNWFCEGSFNGSEKE 58
           SC +PSL+      S      S  G  LPG+     C+    V +  WFCEGSFNGSEKE
Sbjct: 36  SCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKE 95

Query: 59  TMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKIL 118
           TMQFLNDRLA+YLEKVRQLER+NAELE+ I+E  + Q P +C  YQSYFKTIE+ QQKIL
Sbjct: 96  TMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKIL 155

Query: 119 CSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEA 178
            +KSENARLV+QIDNAKLA+DDFRTKYETELSLRQLVE+DINGLRRILDELTLC++DLEA
Sbjct: 156 LTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEA 215

Query: 179 QVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVET 238
           QVESLKEEL+CLK+NHE+EV+ LRCQLGDRLNVEVDAAP VDLN++L + R QYEALVE 
Sbjct: 216 QVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVEN 275

Query: 239 NRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLEN 298
           NRR+VE WF TQTEELN+QVVSSSEQLQ  Q EIIELRRTVNALEIELQAQH++R+SLE+
Sbjct: 276 NRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLES 335

Query: 299 TLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRS 358
           TL E+EARYSSQL+Q+Q LI+NVE+QL+EIR DLERQNQEYQVLLDV+ARLE EI TYR 
Sbjct: 336 TLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRH 395

Query: 359 LLESEDCKLPSNPCAT 374
           LLE EDCKLP  PCAT
Sbjct: 396 LLEGEDCKLPPQPCAT 411


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  528 bits (1361), Expect = e-150
 Identities = 271/392 (69%), Positives = 323/392 (82%), Gaps = 10/392 (2%)

Query: 7   LPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDR 66
           LP+     SC S+  +  SC       A  I  ++   +W+ EG+FNG+EKETMQFLNDR
Sbjct: 52  LPTTFRPASCLSKTYLSSSCQA-----ASGISGSMGPGSWYSEGAFNGNEKETMQFLNDR 106

Query: 67  LASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENAR 126
           LASYL +VRQLE++NAELE+ I+E S  Q   +   YQS+F+TIEELQQKILC+K+ENAR
Sbjct: 107 LASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENAR 166

Query: 127 LVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEE 186
           +VV IDNAKLA+DDFR KYE EL++RQLVE+DINGLRRILD+LTLC++DLEAQVESLKEE
Sbjct: 167 MVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEE 226

Query: 187 LLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQW 246
           L+CLK+NHE+EV +LRCQLGDRLN+EVDAAP VDL +VL E R QYEA+VE NRR+VE+W
Sbjct: 227 LMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEW 286

Query: 247 FATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAR 306
           F  Q EELN+QV +SSEQLQ+YQ++II+LRRTVN LEIELQAQH+LRDSLENTLTESEAR
Sbjct: 287 FNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEAR 346

Query: 307 YSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCK 366
           YSSQL+Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRARLE EINTYRSLLE+EDCK
Sbjct: 347 YSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCK 406

Query: 367 LPSNPCATTNACDKSTGPCISNPCGLRARCGP 398
           LP NPC+T      S   C+ +PC  R  C P
Sbjct: 407 LPCNPCST-----PSCTTCVPSPCVPRTVCVP 433


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  491 bits (1263), Expect = e-139
 Identities = 245/384 (63%), Positives = 305/384 (79%), Gaps = 8/384 (2%)

Query: 21  CVPPSCH-GCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
           C+PP+CH  C LPG C+IP N+  C  + E + NG EKETMQFLNDRLA+YLEKVRQLE+
Sbjct: 68  CLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQ 127

Query: 80  DNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASD 139
           +NAELE  + ERS+  E  VC  YQSYF TIEELQQKILCSK+ENARL+VQIDNAKLA+D
Sbjct: 128 ENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAAD 187

Query: 140 DFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVN 199
           DFR K E+E SLRQLVE+D  G +++LD+ TL ++DLEAQ ESLKEE L LK NHEQEV 
Sbjct: 188 DFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247

Query: 200 TLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVV 259
            LR QLG++L +E+D  PT+DLN+VL E R+QYEA++ETNR++VEQWF  Q+E ++ Q +
Sbjct: 248 ILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDM 307

Query: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLIT 319
           S SE+LQ  Q+EI+ELR TVNALE+E QAQH L+D L+N+L E+E R+ ++L+Q+Q LI+
Sbjct: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLIS 367

Query: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACD 379
           NVE QL+EIR+DLERQNQEYQVLLDV+ RLE EI TYR+LLESEDCKLP NPC+T+ +  
Sbjct: 368 NVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTSPS-- 425

Query: 380 KSTGPCISNPCGLRARCGPCNTFG 403
                C++ PC  R  CGPC T G
Sbjct: 426 -----CVTAPCAPRPSCGPCTTCG 444


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  476 bits (1224), Expect = e-134
 Identities = 245/393 (62%), Positives = 304/393 (77%), Gaps = 11/393 (2%)

Query: 4   SCGLPSLSCRTSCSSRPCVPPS-------CHGCTLP----GACNIPANVSNCNWFCEGSF 52
           SC + +     +C++  C  PS         GC LP    G+CN P  V NC W  +G F
Sbjct: 26  SCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWCEDGVF 85

Query: 53  NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEE 112
             +EKETMQFLNDRLASYLEKVR LE  NAELE+ I+E+ +Q  P+VC  YQ YF TIE+
Sbjct: 86  TSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIED 145

Query: 113 LQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLC 172
           LQQKILC+K+EN+RL VQ+DN KLA+DDF++KYE+ELSLRQL+E+DI+ L  IL+ELTLC
Sbjct: 146 LQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLC 205

Query: 173 RSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQY 232
           +SDLEA VESLKE+LLCLK+NHE+EVN LR QLGDRL+VE+D APT+DLN+VL+E R Q 
Sbjct: 206 KSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQC 265

Query: 233 EALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNL 292
           E ++  NRRE E+W A QTEELN+Q +SS+EQLQ  Q EI+EL+RT +ALEIELQAQ +L
Sbjct: 266 ETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSL 325

Query: 293 RDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECE 352
            +SLE T+ E+EA+YSSQL+Q+Q LI N+E+QLAEIR DLERQNQEYQVLLDV+ARLE E
Sbjct: 326 TESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGE 385

Query: 353 INTYRSLLESEDCKLPSNPCATTNACDKSTGPC 385
           INTY  LL+SED +L  +PC+TT     +  PC
Sbjct: 386 INTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPC 418


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  470 bits (1209), Expect = e-132
 Identities = 239/381 (62%), Positives = 299/381 (78%), Gaps = 4/381 (1%)

Query: 21  CVPPSCH-GCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
           C+PP+ H  C LPG C+IP N+  C  + + + NG EKETM+FLNDRLA+YLEKVRQLE+
Sbjct: 68  CLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQ 127

Query: 80  DNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASD 139
           +NAELE  + ERS+  E  VC  YQSYF+TIEELQQKILCSK+ENARL+VQIDNAKLA+D
Sbjct: 128 ENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAAD 187

Query: 140 DFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVN 199
           DFR K E+E SL QLVE+D  G +++LD+ TL ++DLEAQ ESLKEE L LK NHEQEV 
Sbjct: 188 DFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247

Query: 200 TLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVV 259
            LR QLG++  +E+D  PT+DLN+VL E R+QYEA+VETN ++VEQWF  Q+E ++ Q +
Sbjct: 248 ILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAM 307

Query: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLIT 319
           S SE+LQ  Q+EI+ELR TVNALE+E QAQH L+D L+N+L E+E RY ++L+Q+Q LI+
Sbjct: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLIS 367

Query: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACD 379
           N+E QL+EIR+DLERQNQEYQVLLDV+ARLE EI TYR+LLESEDCKLP NPC+T  +C 
Sbjct: 368 NLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPASCT 427

Query: 380 K--STGPCI-SNPCGLRARCG 397
              S GP    +P G  A  G
Sbjct: 428 SCPSCGPVTGGSPSGHGASMG 448


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  455 bits (1171), Expect = e-128
 Identities = 233/376 (61%), Positives = 295/376 (78%), Gaps = 13/376 (3%)

Query: 36  NIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQ 95
           N   ++ +C+W+ EG  N +EKETMQ LN+RLA+YL+KVR LER+NAELE+ I+E S ++
Sbjct: 77  NARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKE 135

Query: 96  EPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLV 155
            P++C  Y SY+ TIEELQQKILC+K+EN+RLV QIDN KL +DD R KYE E+SLRQLV
Sbjct: 136 LPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLV 195

Query: 156 ESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDA 215
           ESD NGL++IL+ LTL ++DLEAQV+SLKEELLCLK NH++E+N+L+CQLG+RL++EV A
Sbjct: 196 ESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTA 255

Query: 216 APTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIEL 275
           AP+ DLNQVL E R QYE ++ETNR++VEQWF TQ EELN+QVV+SS+Q Q  Q EIIEL
Sbjct: 256 APSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIEL 315

Query: 276 RRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQ 335
           RR+VN LE+ELQAQH +RDS E  LTE+EARY++ L+Q+Q LI N+E+QLAEIR  LERQ
Sbjct: 316 RRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQ 375

Query: 336 NQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCAT----------TNACDKSTGPC 385
           NQEY++LLDV++RLECEI TYRSLLES D K P  P AT           +   +ST P 
Sbjct: 376 NQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPA 435

Query: 386 I--SNPCGLRARCGPC 399
              S+PC L+  C  C
Sbjct: 436 CTSSSPCSLKEHCSAC 451


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  380 bits (977), Expect = e-106
 Identities = 194/322 (60%), Positives = 255/322 (79%)

Query: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFK 108
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 108 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFK 167

Query: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168
           TIE+L+ KIL +  +NA +++QIDNA+LA+DDFRTKYETEL+LR  VE+DINGLRR+LDE
Sbjct: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227

Query: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228
           LTL R+DLE Q+ESLKEEL  LK+NHE+E+N LR Q+G  +NVE+DAAP VDL+++LNE 
Sbjct: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287

Query: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R QYE + E NR++ E+WF T+TEELN++V ++SE +QS ++EI ELRRT+  LEIELQ+
Sbjct: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++ SLEN+L E++ RY  QL+Q+Q +I +VE QLA++R ++E+QNQEY++LLDV+ R
Sbjct: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407

Query: 349 LECEINTYRSLLESEDCKLPSN 370
           LE EI TYR LLE ED  L S+
Sbjct: 408 LEQEIATYRRLLEGEDAHLSSS 429


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  374 bits (959), Expect = e-103
 Identities = 192/321 (59%), Positives = 249/321 (77%)

Query: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFK 108
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 110 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFK 169

Query: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168
           TIE+L+ KI+ +  ENA+ ++QIDNA+LA+DDFRTKYE EL+LRQ VE+D+NGLRR+LDE
Sbjct: 170 TIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDE 229

Query: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228
           LTL R+DLE Q+E LKEEL  L++NHE+E+  LR Q G  +NVE+DAAP VDL+++LNE 
Sbjct: 230 LTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEM 289

Query: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R QYE + E NRR+ E WF ++TEELNK+V S+SE +QS ++E+ ELRR +  LEIELQ+
Sbjct: 290 RDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQS 349

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++ SLEN+L E++ RY  QLSQ+Q LI +VE QLA++R ++E+Q+QEYQ+LLDV+ R
Sbjct: 350 QLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTR 409

Query: 349 LECEINTYRSLLESEDCKLPS 369
           LE EI TYR LLE ED  L S
Sbjct: 410 LEQEIATYRRLLEGEDAHLSS 430


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  373 bits (958), Expect = e-103
 Identities = 209/384 (54%), Positives = 269/384 (70%), Gaps = 25/384 (6%)

Query: 4   SCGLPSLSCRTSCS-SRPCVPPSCH-------GCTLPGACNIPANVSNCNWF-------- 47
           S GL   S RTSC  S      SC        G TL G+     + S+C  F        
Sbjct: 17  SSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGS-----SYSSCYSFGSGGGYGS 71

Query: 48  ----CEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASY 103
                +G   G EK TMQ LNDRLASYL+KVR LE  N ELE  IR+  Q+Q P     Y
Sbjct: 72  SFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDY 131

Query: 104 QSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLR 163
             Y++TIEELQ KIL +  +NA +++QIDNA+LA+DDFRTK+ETE +LR  VE+DINGLR
Sbjct: 132 SQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLR 191

Query: 164 RILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQ 223
           R+LDELTL R+DLE Q+E+LKEEL  LK+NHE+E+N LR Q+G  +NVE+DAAP VDL++
Sbjct: 192 RVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSR 251

Query: 224 VLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALE 283
           +LNE R QYE + E NR++ E WF ++TEELN++V ++SE +QS ++EI ELRRT+ ALE
Sbjct: 252 ILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALE 311

Query: 284 IELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLL 343
           IELQ+Q +++ SLE  L E+E RY  QLSQ+Q LI +VE QLA++R ++E+QNQEY++LL
Sbjct: 312 IELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILL 371

Query: 344 DVRARLECEINTYRSLLESEDCKL 367
           DV+ RLE EI TYR LLE ED  L
Sbjct: 372 DVKTRLEQEIATYRRLLEGEDAHL 395


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  360 bits (925), Expect = e-99
 Identities = 184/319 (57%), Positives = 246/319 (77%), Gaps = 1/319 (0%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVC-ASYQSYFK 108
           G  +G+EK TMQ LNDRLASYL+KVR LE  NA+LE  I +  Q+Q P      Y  YFK
Sbjct: 99  GLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFK 158

Query: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168
           TIEEL+ KI+ +  +N+R++++IDNA+LA+DDFR KYE EL+LRQ VE+DINGLRR+LDE
Sbjct: 159 TIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDE 218

Query: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228
           LTL R+DLE Q+E L EEL  LK+NHE+E+     QL  ++NVE+DAAP VDL +VL E 
Sbjct: 219 LTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEM 278

Query: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R QYEA+ E NRR+VE WF ++TEELNK+V S++E +Q+ + EI +LRRT+  LEIELQ+
Sbjct: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++  LEN+L E+E RY++QL Q+Q LI  +E+QL+E+R ++E QNQEY++LLD++ R
Sbjct: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398

Query: 349 LECEINTYRSLLESEDCKL 367
           LE EI TYRSLLE +D K+
Sbjct: 399 LEQEIATYRSLLEGQDAKM 417


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  360 bits (924), Expect = 1e-99
 Identities = 179/316 (56%), Positives = 249/316 (78%)

Query: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFK 108
           +G   G+EK TMQ LNDRLASYL+KVR LE  N ELE  IR+  Q+Q P     Y  Y+ 
Sbjct: 73  DGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYT 132

Query: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168
           TI++L+ KIL +  EN+R+V+QIDNA+LA+DDFRTK+ETE +LR  VE+DINGLRR+LDE
Sbjct: 133 TIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDE 192

Query: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228
           LTL R+DLE Q+E LKEEL  LK+NHE+E++TLR Q+G +++VEVD+AP  DL ++L++ 
Sbjct: 193 LTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDM 252

Query: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           RSQYE + E NR++ E WF ++TEELN++V   +EQLQ  ++E+ +LRRT+  LEIELQ+
Sbjct: 253 RSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQS 312

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++ +LE+TL E+EAR+ +QL+ +Q LI+ +E+QL ++R+D ERQNQEYQ L+D+++R
Sbjct: 313 QLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSR 372

Query: 349 LECEINTYRSLLESED 364
           LE EI TYRSLLE ++
Sbjct: 373 LEQEIATYRSLLEGQE 388


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  354 bits (908), Expect = 9e-98
 Identities = 183/337 (54%), Positives = 251/337 (74%), Gaps = 2/337 (0%)

Query: 48  CEGSF-NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCA-SYQS 105
           C+G    G+EK TMQ LNDRLASYLEKVR LE  NA+LE  IR+   +Q P      Y  
Sbjct: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154

Query: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165
           Y+KTIEEL+ KIL +  EN R++++IDNA+LA+DDFR KYE EL+LRQ VE+DINGLRR+
Sbjct: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214

Query: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225
           LDELTL ++DLE Q+ESL EEL  +K+NHE+E+     Q+  ++NVE+DA P +DL +VL
Sbjct: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274

Query: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
            E R QYEA+ E NRR+ E+WF  ++ ELNK+V +++  +Q+ + EI ELRRT+  LEIE
Sbjct: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+Q +++  LENT+ E+E RY+ QL Q+Q LI+++E+QL+E+RS++E QNQEY++LLD+
Sbjct: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394

Query: 346 RARLECEINTYRSLLESEDCKLPSNPCATTNACDKST 382
           + RLE EI TYRSLLE +D K+   P +  +   +ST
Sbjct: 395 KTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRST 431


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  350 bits (898), Expect = 1e-96
 Identities = 181/326 (55%), Positives = 245/326 (75%), Gaps = 2/326 (0%)

Query: 48  CEGSF-NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCA-SYQS 105
           C+G    G+EK TMQ LNDRLASYLEKVR LE  NA+LE  IR+   +Q P      Y  
Sbjct: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154

Query: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165
           Y+KTIEEL+ KIL +  EN R++++IDNA+LA+DDFR KYE EL+LRQ VE+DINGLRR+
Sbjct: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214

Query: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225
           LDELTL ++DLE Q+ESL EEL  +K+NHE+E+     Q+  ++NVE+DA P +DL +VL
Sbjct: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274

Query: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
            E R QYEA+ E NRR+ E+WF  ++ ELNK+V +++  +Q+ + EI ELRRT+  LEIE
Sbjct: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+Q +++  LENT+ E+E RY+ QL Q+Q LI+++E+QL+E+RS++E QNQEY++LLD+
Sbjct: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394

Query: 346 RARLECEINTYRSLLESEDCKLPSNP 371
           + RLE EI TYRSLLE +D K    P
Sbjct: 395 KTRLEQEIATYRSLLEGQDAKKRQPP 420


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  332 bits (851), Expect = 4e-91
 Identities = 179/320 (55%), Positives = 233/320 (72%), Gaps = 9/320 (2%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE------RSQQQEPLVCASY 103
           G  +G+EK TMQ LNDRLASYL+KVR LE  N ELE  I+E       S Q EP     Y
Sbjct: 140 GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEP---RDY 196

Query: 104 QSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLR 163
             Y+KTI++L+ +IL   ++NA +++QIDNA+LA+DDFR KYE E++LRQ VE+DINGLR
Sbjct: 197 SKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLR 256

Query: 164 RILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQ 223
           R+LDELTL ++DLE Q+ESL EEL  LK+NHE+E+  LR      +NVE++AAP VDL Q
Sbjct: 257 RVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQ 316

Query: 224 VLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALE 283
           +LN  RSQYE L E NR++ E WF  +++EL  ++ ++ EQ+ SY++EI ELRR V ALE
Sbjct: 317 LLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALE 376

Query: 284 IELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLL 343
           IELQ+Q  L+ SLE +L E+E RY  QLSQ+Q  I+ +E QL +IR++ E QN EYQ LL
Sbjct: 377 IELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLL 436

Query: 344 DVRARLECEINTYRSLLESE 363
           D++ RLE EI TYRSLLE E
Sbjct: 437 DIKIRLENEIQTYRSLLEGE 456


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  331 bits (849), Expect = 6e-91
 Identities = 173/318 (54%), Positives = 236/318 (74%), Gaps = 4/318 (1%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE----RSQQQEPLVCASYQS 105
           G  +GSEKETMQ LNDRLASYL+KVR LE  N ELEN IRE    R         + Y  
Sbjct: 119 GLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSK 178

Query: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165
           Y+  IE+L+ KI+ +   NA+L++QIDNA+LA++DFR KYE EL+LRQ VE+DINGLRR+
Sbjct: 179 YYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRV 238

Query: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225
           LDELTL R+DLE Q+ESL EEL  +K+NHE E+ + R      ++VE+DAAP VDL ++L
Sbjct: 239 LDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLL 298

Query: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
           N+ R+QYE + E NR++ E WF  ++ EL K++ +++EQLQS ++E+ +LRR    LEIE
Sbjct: 299 NDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIE 358

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+Q  ++ SLE++L E+E  Y +QLSQVQ+LI+N+E+QL ++R+D ERQN ++Q LL+V
Sbjct: 359 LQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNV 418

Query: 346 RARLECEINTYRSLLESE 363
           +ARLE EI TYR LL+ E
Sbjct: 419 KARLELEIETYRRLLDGE 436


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  313 bits (801), Expect = 2e-85
 Identities = 159/328 (48%), Positives = 235/328 (71%)

Query: 52  FNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIE 111
           F G+EK  MQ LNDRLASYLEKVR LE+ N++LE  I++  +   P     Y +Y++ IE
Sbjct: 66  FVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIE 125

Query: 112 ELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTL 171
           EL+ +I  ++ +NAR V+QIDNAKLA++DFR KYETE  +R  VE+D+ GL ++ D+LTL
Sbjct: 126 ELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTL 185

Query: 172 CRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQ 231
            ++DLE Q+E L ++L  LK+ H++EV+ L   LG+ +NVEVDAAP ++L  ++NE R +
Sbjct: 186 HKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQK 245

Query: 232 YEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHN 291
           YE + + N +E ++ F  QT  L +QV  ++E+L+  + ++ ELRRT  +LEIELQ+  +
Sbjct: 246 YEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLS 305

Query: 292 LRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLEC 351
           +++SLE+TL E++ARYSSQL+ +Q L++++E+QL +IRS++ERQN EY +LLD++ RLE 
Sbjct: 306 MKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQ 365

Query: 352 EINTYRSLLESEDCKLPSNPCATTNACD 379
           EI TYR LLE ED K      +T    D
Sbjct: 366 EIATYRRLLEGEDVKTTEYQLSTLEERD 393


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  306 bits (783), Expect = 3e-83
 Identities = 172/387 (44%), Positives = 242/387 (62%), Gaps = 24/387 (6%)

Query: 4   SCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFC---EGSFNGSEKETM 60
           +CG+P +    SC+         +G  L G        ++C  F     G  +G+EK TM
Sbjct: 35  TCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGS------ASCAAFTGNEHGLLSGNEKVTM 88

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCAS----YQSYFKTIEELQQK 116
           Q LNDRLASYLE VR LE  NA+LE  I+   ++  P  C      Y  YF  I+EL+ +
Sbjct: 89  QNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQ 148

Query: 117 ILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDL 176
           I+ + + NA +V+Q DNA+L +DDFR K+E EL+L Q VE+DINGLRR+LDELTLCR+DL
Sbjct: 149 IISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDL 208

Query: 177 EAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALV 236
           E Q+E+L EEL  LK+NHE+E+  L+C  G  +NVE++AAP VDL  +LN  R++YEAL 
Sbjct: 209 EIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALA 268

Query: 237 ETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSL 296
           E NRR+ E WF  ++  L +Q+   +    S + E+IE++RT+  LEIELQ+    + SL
Sbjct: 269 EQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSL 328

Query: 297 ENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTY 356
           E +LTE+E+ Y +QL+Q+Q  I  +E QL ++R++ E Q  EY+ LLD++  LE EI TY
Sbjct: 329 ECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETY 388

Query: 357 RSLLESEDCKLPSNPCATTNACDKSTG 383
             L++ ED            +C KS G
Sbjct: 389 CLLIDGED-----------GSCSKSKG 404


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  300 bits (768), Expect = 2e-81
 Identities = 162/338 (47%), Positives = 224/338 (66%), Gaps = 15/338 (4%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCAS----YQS 105
           G  +G+EK TMQ LNDRLASYL+ VR LE  NAELE  I+   ++  P  C      Y  
Sbjct: 80  GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139

Query: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165
           Y  TIE+L+ KI+ S + NA +++QIDNA+LA+DDFR KYE EL+L Q VE+DINGLRR+
Sbjct: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199

Query: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225
           LDELTLCR+D E Q ESL EE+  LK+NHE+E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259

Query: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
           N  R++YEAL E NR++ E WF  ++  L +Q+   S      ++++ E+RRT+  LEI+
Sbjct: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q  I  +E QL ++R++ E Q  EY+ LLDV
Sbjct: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379

Query: 346 RARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTG 383
           +  LE EI TY  L++ +            N+C KS G
Sbjct: 380 KVHLEKEIETYCRLIDGDG-----------NSCSKSKG 406


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  297 bits (761), Expect = 1e-80
 Identities = 156/319 (48%), Positives = 220/319 (68%), Gaps = 5/319 (1%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVC-----ASYQ 104
           G F+G EK+TMQ LNDRLA+YL+KVR LE  N +LEN I+E   +  P          Y 
Sbjct: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193

Query: 105 SYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRR 164
            Y+  IE+L+ +I+ +  ENA +++ IDNA+LA+DDFR KYE EL LRQ VE+DINGLR+
Sbjct: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253

Query: 165 ILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQV 224
           +LD+LT+ RSDLE Q+ES  EEL  L++NHE+E+  ++   G  + VE++AAP  DL ++
Sbjct: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313

Query: 225 LNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEI 284
           LN+ R+QYE L E NRRE E+ F  Q+  L  Q+ + +    S + EI EL+RT+ ALEI
Sbjct: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373

Query: 285 ELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLD 344
           ELQ+Q  ++ SLE TL ++EA Y +QLS++Q  I+ +E ++ +I  + + QN EY+ LLD
Sbjct: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433

Query: 345 VRARLECEINTYRSLLESE 363
           ++ RLE EI TYR LL+ E
Sbjct: 434 IKTRLEVEIETYRRLLDGE 452


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  293 bits (751), Expect = 1e-79
 Identities = 152/315 (48%), Positives = 228/315 (72%), Gaps = 3/315 (0%)

Query: 55  SEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQ 114
           +EKETMQ LNDRLASYL++VR LE +N  LE+ IRE  +++ P V   +  YFK IE+L+
Sbjct: 79  NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137

Query: 115 QKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRS 174
            +I  +  +NAR+V+QIDNA+LA+DDFR KYETEL++RQ VE+DI+GLR+++D+  + R 
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197

Query: 175 DLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNQVLNETRSQYE 233
            LE ++E+LKEELL +K+NHE+EV  L+ Q+    L VEVDA  + DL +++ + R+QY+
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257

Query: 234 ALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
            L   NR E++++++ Q EE    V + S ++ + +  + ELRRTV +LEI+L +  NL+
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317

Query: 294 DSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
            SLEN+L E EARY+ Q+ Q+  ++ ++ES+LA+ R++ +RQ QEY+ LL+++ +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377

Query: 354 NTYRSLLE-SEDCKL 367
            TYR LLE  ED  L
Sbjct: 378 ATYRRLLEDGEDFNL 392


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  293 bits (751), Expect = 1e-79
 Identities = 152/315 (48%), Positives = 228/315 (72%), Gaps = 3/315 (0%)

Query: 55  SEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQ 114
           +EKETMQ LNDRLASYL++VR LE +N  LE+ IRE  +++ P V   +  YFK IE+L+
Sbjct: 79  NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137

Query: 115 QKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRS 174
            +I  +  +NAR+V+QIDNA+LA+DDFR KYETEL++RQ VE+DI+GLR+++D+  + R 
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197

Query: 175 DLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNQVLNETRSQYE 233
            LE ++E+LKEELL +K+NHE+EV  L+ Q+    L VEVDA  + DL +++ + R+QY+
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257

Query: 234 ALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
            L   NR E++++++ Q EE    V + S ++ + +  + ELRRTV +LEI+L +  NL+
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317

Query: 294 DSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
            SLEN+L E EARY+ Q+ Q+  ++ ++ES+LA+ R++ +RQ QEY+ LL+++ +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377

Query: 354 NTYRSLLE-SEDCKL 367
            TYR LLE  ED  L
Sbjct: 378 ATYRRLLEDGEDFNL 392


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  291 bits (746), Expect = 5e-79
 Identities = 154/323 (47%), Positives = 217/323 (67%), Gaps = 6/323 (1%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCAS----YQS 105
           G  +G+EK TMQ LNDRLASYL+ V  LE  NA+LE  I+   ++  P  C      Y  
Sbjct: 73  GLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 132

Query: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165
           YF  I++L+ +I+ S + NA  V+QIDNA+L +DDFR KYE EL+L Q VE+D+NGLRR+
Sbjct: 133 YFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRV 192

Query: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225
           LDE+TLCR+DLE Q E+L EE+  LK+NH++E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 193 LDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLL 252

Query: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
           N  R++YEAL E NRR+ E WF  ++  L +Q+        S + E+ E++RT+  LEIE
Sbjct: 253 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIE 312

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q  I  +E QL ++R++ E Q  EY+ LLD+
Sbjct: 313 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 372

Query: 346 RARLECEINTYRSLLESED--CK 366
           +  LE EI TY  L+  +D  CK
Sbjct: 373 KLHLEKEIETYCLLIGGDDGACK 395


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  270 bits (689), Expect = 2e-72
 Identities = 137/313 (43%), Positives = 214/313 (68%), Gaps = 1/313 (0%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPL-VCASYQSYFK 108
           G    +EK TMQ LN RLASYL+KV+ LE  N +LEN I++   ++ P  +  +Y  Y+ 
Sbjct: 147 GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYN 206

Query: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168
           TI++L+ +I+     N + ++ IDN ++  DDFR K+E E +LRQ V++DINGLR++LD 
Sbjct: 207 TIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDN 266

Query: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228
           LT+ +SDLE Q E+L+EEL+ LK+NH++E++ L  Q    +NVE++ AP  DL + LN+ 
Sbjct: 267 LTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDM 326

Query: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R +YE L+  NR+++E  + TQ  ++  +V SS +++QS   E+ +LR  V  LEIELQ+
Sbjct: 327 RQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQS 386

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q + + +LE +L +++ RY  QL  +Q  I+N+E+Q+ ++R ++E QNQEY +LL ++ R
Sbjct: 387 QLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMR 446

Query: 349 LECEINTYRSLLE 361
           LE EI TY +LLE
Sbjct: 447 LEKEIETYHNLLE 459


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  268 bits (685), Expect = 6e-72
 Identities = 137/310 (44%), Positives = 210/310 (67%), Gaps = 1/310 (0%)

Query: 54  GSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEEL 113
           G+ K TMQ LNDRLASYLEKVR LE  N +LE+ I +  QQ++P     Y  Y + I  L
Sbjct: 70  GNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHL 129

Query: 114 QQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCR 173
           Q++I+  K  NA++++ IDNA++A DDF  KYE E S ++ +E ++ GLRR LD LT+  
Sbjct: 130 QEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVT 189

Query: 174 SDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYE 233
           +DLE +VE +++EL+ +K++HEQE+          +NV+VD  P  DL +VL + R +YE
Sbjct: 190 TDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYE 249

Query: 234 ALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
            +++   R+++ W+  Q+  ++++  S +  +QS Q +I EL+RT  ALEI+LQ Q++ +
Sbjct: 250 LIIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQALEIDLQTQYSTK 308

Query: 294 DSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
            +LEN L+E+++RYS +L  +Q +I++ E +L ++R +LERQN EYQVLL ++  LE EI
Sbjct: 309 SALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEI 368

Query: 354 NTYRSLLESE 363
            TYR LLE E
Sbjct: 369 TTYRRLLEGE 378


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  267 bits (683), Expect = 1e-71
 Identities = 159/374 (42%), Positives = 224/374 (59%), Gaps = 22/374 (5%)

Query: 25  SCHGCTLPGA------CNIPANVSN--CNWFCEGS---FNGSEKETMQFLNDRLASYLEK 73
           S   CTL G       CN    + +  C  F        +G+EK TMQ LNDRLASYL+ 
Sbjct: 41  SSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDH 100

Query: 74  VRQLERDNAELENLIRERSQQQEPLVCAS----YQSYFKTIEELQQKILCSKSENARLVV 129
           V  LE  NA+LE  I+ R ++ EP         Y  YF  IE+L+++I  +   NA +V+
Sbjct: 101 VHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVL 160

Query: 130 QIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLC 189
           Q DNA+L +DDFR KYE EL+L   VE+D +GLRR+LDELTLC +DLE Q E+L EEL  
Sbjct: 161 QNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTY 220

Query: 190 LKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFAT 249
           LK++HE+E+  L+   G  +NVE++A P VDL  +LN  R++YE L E NR++ E WF  
Sbjct: 221 LKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNE 280

Query: 250 QTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSS 309
           ++  L +Q+        + + E+ EL+R +  LEIELQ+   ++ S E +L E+E  Y +
Sbjct: 281 RSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCN 340

Query: 310 QLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPS 369
           QL Q+Q  I  +E QL +IR++ E Q  EY+ LLDV+  LE EI+ Y +LL+ E+ K   
Sbjct: 341 QLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK--- 397

Query: 370 NPCATTNACDKSTG 383
               + + C KS G
Sbjct: 398 ----SKSTCYKSKG 407


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,332,213
Number of Sequences: 37866
Number of extensions: 616877
Number of successful extensions: 6730
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 218
Number of HSP's successfully gapped in prelim test: 596
Number of HSP's that attempted gapping in prelim test: 4192
Number of HSP's gapped (non-prelim): 2216
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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