Guide to the Human Genome
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Search of human proteins with 148762978

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148762978 similar to CG15216-PA [Homo sapiens]
         (976 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148762978 similar to CG15216-PA [Homo sapiens]                    2034   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    75   4e-13
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         62   3e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    61   6e-09
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               56   2e-07
gi|239755710 PREDICTED: hypothetical protein [Homo sapiens]            55   4e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   4e-06
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            52   4e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    52   4e-06
gi|118402590 myosin XV [Homo sapiens]                                  51   6e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     49   2e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      48   4e-05
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               48   4e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   5e-05
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]      47   7e-05
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                47   7e-05
gi|239757987 PREDICTED: hypothetical protein [Homo sapiens]            47   9e-05
gi|239741896 PREDICTED: hypothetical protein XP_002342335 [Homo ...    47   1e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    47   1e-04
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       47   1e-04
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       47   1e-04
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    47   1e-04
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]               47   1e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  46   1e-04
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    46   1e-04
gi|188536004 zinc finger protein 469 [Homo sapiens]                    46   1e-04
gi|40353727 synaptopodin isoform A [Homo sapiens]                      46   1e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          46   1e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          46   1e-04
gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo ...    46   2e-04

>gi|148762978 similar to CG15216-PA [Homo sapiens]
          Length = 976

 Score = 2034 bits (5270), Expect = 0.0
 Identities = 976/976 (100%), Positives = 976/976 (100%)

Query: 1   MTRTDPPDLLVSTVYQDIKVATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALD 60
           MTRTDPPDLLVSTVYQDIKVATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALD
Sbjct: 1   MTRTDPPDLLVSTVYQDIKVATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALD 60

Query: 61  GPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREA 120
           GPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREA
Sbjct: 61  GPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREA 120

Query: 121 QRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP 180
           QRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP
Sbjct: 121 QRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP 180

Query: 181 APHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPT 240
           APHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPT
Sbjct: 181 APHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPT 240

Query: 241 PSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGP 300
           PSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGP
Sbjct: 241 PSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGP 300

Query: 301 TFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRY 360
           TFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRY
Sbjct: 301 TFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRY 360

Query: 361 VPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDP 420
           VPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDP
Sbjct: 361 VPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDP 420

Query: 421 DPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREP 480
           DPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREP
Sbjct: 421 DPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREP 480

Query: 481 RGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDL 540
           RGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDL
Sbjct: 481 RGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDL 540

Query: 541 RATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASE 600
           RATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASE
Sbjct: 541 RATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASE 600

Query: 601 PAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSADED 660
           PAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSADED
Sbjct: 601 PAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSADED 660

Query: 661 DLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCR 720
           DLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCR
Sbjct: 661 DLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCR 720

Query: 721 HVLQFCRDSGPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYL 780
           HVLQFCRDSGPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYL
Sbjct: 721 HVLQFCRDSGPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYL 780

Query: 781 SLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSH 840
           SLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSH
Sbjct: 781 SLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSH 840

Query: 841 GPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFI 900
           GPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFI
Sbjct: 841 GPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFI 900

Query: 901 HIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEP 960
           HIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEP
Sbjct: 901 HIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEP 960

Query: 961 RALDWVASANLLDDIM 976
           RALDWVASANLLDDIM
Sbjct: 961 RALDWVASANLLDDIM 976


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 151/646 (23%), Positives = 196/646 (30%), Gaps = 150/646 (23%)

Query: 35   SVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESA-VPRART----------R 83
            +++ P  P   +     S  F  + D PA    P PP P+ A  P A T           
Sbjct: 823  NLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPP 882

Query: 84   EAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALA 143
            +  P     +   P+  P  TPAP   P L      + + ARA  +P+  PA P+ +   
Sbjct: 883  KETPTPSVVNLPFPKEGPA-TPAPKQAPALSMTS-SSPKKARATPAPKGIPASPSPKGAP 940

Query: 144  NELHPIKLQPQ-RGGPGRVAPLCAAAGRCA-PPEPPAGPAPHVRCRLDIKPDDAVLQHAT 201
                P    P  +GGP   +P  A     A PP P  GPA                    
Sbjct: 941  TP--PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA-------------------- 978

Query: 202  RGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGP 261
              S    PT  A  A P     G   P P+       PTP       P+      P P  
Sbjct: 979  TPSPKGAPTPPA--ATPPSPKGGPATPSPK-----GAPTPPAVTPPSPKGSPAATPFP-- 1029

Query: 262  RDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPR 321
                   + P  TPP P            +GS AA+P P      P         GP+  
Sbjct: 1030 ---KGASTPPAATPPSP------------KGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 322  RMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGR 381
             + G       T P   PPS       P   G P  P   P  P+               
Sbjct: 1075 SLKG-----APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG------------- 1116

Query: 382  YRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVP----PSDPDPLLASWHGGTGTSPPR 437
                     T PH  +    A   P P   L   P    P+ P     S  GG  T PP+
Sbjct: 1117 -------LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169

Query: 438  LATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRG--VSPEGRRPPVVVN 495
             A  +              P    P  +G       G     P+G   +P    P     
Sbjct: 1170 GAPTT--------------PAATPPSPKG-------GLATPSPKGAPTTPAATPPSPKGG 1208

Query: 496  LSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPG 555
            L+T   + A  + + T  + KG    GL            T +   A   P+A      G
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKG----GLA-----------TPSPKGAPTTPAATPPSPKG 1253

Query: 556  GRTRPPPHAAPDGPTS------GRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQ 609
            G   PPP  AP  P +      G   +          +V    P  G A+ P        
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP-------- 1305

Query: 610  LRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEP 655
                    P G+  P  A P SP  S G+     AP   A   P P
Sbjct: 1306 --------PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 151/672 (22%), Positives = 207/672 (30%), Gaps = 160/672 (23%)

Query: 21   ATPGPASKCSPCERSVARP----AEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESA 76
            ATP P    +P   +   P    A P+P            +    P   T P P    +A
Sbjct: 978  ATPSPKGAPTPPAATPPSPKGGPATPSP------------KGAPTPPAVTPPSPKGSPAA 1025

Query: 77   VPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAY 136
             P  +     P   A +  +P+  P  TP P   P  P         A    SP+  PA 
Sbjct: 1026 TPFPKGASTPP---AATPPSPKGSPAATPLPKGAPTTP---------AATLPSPKGGPAT 1073

Query: 137  PALRALANELHPIKLQPQ-RGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDA 195
            P+L+       P    P  +GGP   +P  A       P PPA   P  +  L   P   
Sbjct: 1074 PSLKGAPTP--PAATPPSPKGGPATPSPKGA-------PMPPAATPPSPKGGLATPPHKG 1124

Query: 196  VLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCD 255
                         PT  A  A P     GL  P P+    +   TP       P+     
Sbjct: 1125 A------------PTTPA--ATPPSPKGGLATPPPKGAPTTPAATPPS-----PKGGLAT 1165

Query: 256  GPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEEL 315
             P  G        + P  TPP P     T  P+G   + AA+P          P P   L
Sbjct: 1166 PPPKGAP------TTPAATPPSPKGGLATPSPKGAPTTPAATP----------PSPKGGL 1209

Query: 316  SGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFY 375
            + PSP+           T P   PPS       P   G P  P   P  P+      P  
Sbjct: 1210 ATPSPKG--------APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP-- 1259

Query: 376  TEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSD--PDPLLA---SWHGG 430
                               P+ +P      P   +     PP    P+P +    S  GG
Sbjct: 1260 -------------------PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300

Query: 431  TGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRP 490
              TSPP+ A                 P    P  +G             P    P+G   
Sbjct: 1301 PATSPPKGAPTP--------------PAATPPSPKG------------SPGTPPPKGAPT 1334

Query: 491  PVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARA 550
            P  V   T P      +L  T+ + KG       +     P  T +     A   PS + 
Sbjct: 1335 PPAV---TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK- 1390

Query: 551  WELPGGRTRPPPHAAPDG-PTSGRQRSLEQLDELITDLVID--SRPTAGQASEPAADCLG 607
                    R P   +P G PTS     L       T +  +  + P+ G  + PA   + 
Sbjct: 1391 --------RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442

Query: 608  PQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSADEDDLMTCSN 667
              L++          APA + P+  PA+  S  +P  P     +  EP A +    + S 
Sbjct: 1443 --LKK----------APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 668  ARCRRTETMFNA 679
             +   T     A
Sbjct: 1491 KKAPATPAPMGA 1502



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 147/637 (23%), Positives = 196/637 (30%), Gaps = 120/637 (18%)

Query: 21   ATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRA 80
            ATP P    +P       PA   P  K    +  F +    P   T P P    +A P  
Sbjct: 1001 ATPSPKGAPTP-------PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053

Query: 81   RTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALR 140
            +     P     S     A P L  AP  P   P     + +   A  SP+  P  PA  
Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP----PSPKGGPATPSPKGAPMPPAAT 1109

Query: 141  ALANELHPIKLQPQRGGPGRVA--PLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQ 198
               +    +   P +G P   A  P     G   P  PP G AP         P   +  
Sbjct: 1110 P-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATP--PPKG-APTTPAATPPSPKGGLAT 1165

Query: 199  HATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPL 258
               +G+    PT  A  A P     GL  P P+    +   TP       P+        
Sbjct: 1166 PPPKGA----PTTPA--ATPPSPKGGLATPSPKGAPTTPAATP-----PSPKGGLA---T 1211

Query: 259  PGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGP 318
            P P+      + P  TPP P     T  P+G   + AA+P          P P    + P
Sbjct: 1212 PSPKG---APTTPAATPPSPKGGLATPSPKGAPTTPAATP----------PSPKGGPATP 1258

Query: 319  SPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTED 378
             P+           T P   PPS       P   G P      P  P+      P     
Sbjct: 1259 PPK--------GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP----- 1305

Query: 379  FGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRL 438
                      A T P P+ SP      P+   T   V P  P         GT T  P  
Sbjct: 1306 --PKGAPTPPAATPPSPKGSPGTPP--PKGAPTPPAVTPPSPK--------GTPTL-PAT 1352

Query: 439  ATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLST 498
               S+    +  +   P P    P  +G             P    P  +R P + +   
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKG------------GPAMTPPSPKRGPAIPSPKG 1400

Query: 499  SPRRYAALSLS-----ETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWEL 553
             P   A + LS      T +T +G A    G    +TP   +T   L+     SA     
Sbjct: 1401 DPTSPAVIPLSPKKAPATPVTREGAATPSKGD---LTPP-AVTPVSLKKAPATSA----- 1451

Query: 554  PGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRL 613
                    P   P  P+S    +L          V    P    A +  A    P   + 
Sbjct: 1452 --------PKGGPATPSSKGDPTL--------PAVTPPSPKEPPAPKQVATSSSP---KK 1492

Query: 614  LDSRPAGSGAPAL-----APPRSPPASAGSAEEPAAP 645
              + PA  GAP L     + P+  PA+  S  +P AP
Sbjct: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 112/482 (23%), Positives = 152/482 (31%), Gaps = 70/482 (14%)

Query: 66   TLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAAR 125
            TLP   P     P   + +  P   A + S    P    P+P   P +P    +    A 
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407

Query: 126  AEASPRREPAYPALRALANELHPIKLQPQRGG--PGRVAP--LCAAAGRCAPPEPPAGPA 181
               SP++ PA P  R  A         P +G   P  V P  L  A    AP   PA P+
Sbjct: 1408 IPLSPKKAPATPVTREGA-------ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPS 1460

Query: 182  PHVRCRLDI------KPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMAL 235
                  L        K   A  Q AT  S    P   A     AP    +    P+   +
Sbjct: 1461 SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG--APTLPAVIPSSPKE--V 1516

Query: 236  SRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGS-- 293
              TP+      A P A       P      E    P  T P P +      P+    +  
Sbjct: 1517 PATPSSRRDPIA-PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS 1575

Query: 294  ---FAASPGPTFDAYYPRPYPSEEL-----SGPSPRRMGGYYAGEVRTFPIQEPPSRSYY 345
                ++ P  T   Y   P P E L     + PSP+        E  T P   PPS    
Sbjct: 1576 SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK--------EAPTPPAVTPPSPEKG 1627

Query: 346  GEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGR---YRERDVLAR----------TY 392
               P   G P  P   P   +   T+    T   G       + + A+            
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687

Query: 393  PHPRSSP---AWADWGPRPYRTLQVVPPSDPDPLLASWHGG---TGTSPPRL-------- 438
            P P S+P   A    GP+  ++    PP  PDP   +   G   T    P L        
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 439  ATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLST 498
                +  S S    LAP   +        ++E +L +        +P    PPV + L+ 
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS---PPVSLPLAP 1804

Query: 499  SP 500
            SP
Sbjct: 1805 SP 1806



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 51/217 (23%), Positives = 74/217 (34%), Gaps = 48/217 (22%)

Query: 56   LEALDGPAM--ETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAP----------PGL 103
            L A  GP    E L  P P  + +  A TR+    +++ + S P  P          P  
Sbjct: 1672 LPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS 1731

Query: 104  TPAPASPPVLP--------RRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQR 155
            T APA  P+LP         +G++A  + +   +P    A   L A A E          
Sbjct: 1732 TVAPA--PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE---------- 1779

Query: 156  GGPGRVAPLCAAAGRCAPPEPPA------GPAPHVRCRLDIKPDD--AVLQHATRGSRSC 207
                +V P   +A   A P PP        P P +  +    P     VL+  ++     
Sbjct: 1780 ----KVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835

Query: 208  GPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDS 244
               E      P P   G+    P    L   PTP  +
Sbjct: 1836 DEDELLPLIPPEPISGGV----PFQSVLVNMPTPKSA 1868



 Score = 30.4 bits (67), Expect = 8.4
 Identities = 20/52 (38%), Positives = 22/52 (42%), Gaps = 8/52 (15%)

Query: 825  APPGTPALPAPAPRSH-GPTVRKF-------AKVALAAGSPARPPPARSREP 868
            +P GTP LPA  P S  GPT           A      G PA  PP+  R P
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 170/677 (25%), Positives = 231/677 (34%), Gaps = 119/677 (17%)

Query: 30  SPCERSVARPAEPAPFNKRHC----------------RSFDFLEALDGPAMETLPEP--P 71
           SP  R+ +R   PAP  K                    +    + L  P  E +PEP  P
Sbjct: 200 SPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP 259

Query: 72  PPESAVPRARTRE-AEPRRRARSKSAPRAPPGLTPAPA-SPPVLPRRGREAQRAARAEAS 129
            PE    + + +E   PR R+RSKS  R     + +P+ + P    R R    + R   S
Sbjct: 260 SPEKNSKKEKEKEKTRPRSRSRSKSRSRT---RSRSPSHTRPRRRHRSRSRSYSPRRRPS 316

Query: 130 PRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLD 189
           PRR P+ P  R     + P    P R    R +P+       A     +  +   R R  
Sbjct: 317 PRRRPS-PRRRTPPRRMPP----PPRHRRSR-SPVRRRRRSSASLSGSSSSSSSSRSRSP 370

Query: 190 IKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDS-YCAD 248
            K          R +R   P+ +    R  P       P  RH     +PTP  S     
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH-----SPTPQQSNRTRK 425

Query: 249 PRAFYCDGPLPG---PRDYAERRSLPFTTP-PGPTQFFYTEEPQGFRGSFAASPGPTFDA 304
            R     G   G        E+R  P   P P   +   +EE +G  G  AA+       
Sbjct: 426 SRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG--GKMAAADSVQQRR 483

Query: 305 YYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYY--GEAPRAYGLPYGPRYVP 362
            Y R   +++ S  S    G   + E       E P RS+   GE  R            
Sbjct: 484 QYRR--QNQQSSSDS----GSSSSSE------DERPKRSHVKNGEVGRR----------- 520

Query: 363 EEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDPDP 422
              R HS +R        R +E     R     R SP+     P P R  +   P+ P  
Sbjct: 521 ---RRHSPSRSASPSPRKRQKETSPRGRR----RRSPS-----PPPTRRRRSPSPAPPPR 568

Query: 423 LLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRR-EDPLGRGRSYENLLGREVREP- 480
                   T T PPR  T S    R      +P PRR   P+ R  S      R    P 
Sbjct: 569 -----RRRTPTPPPRRRTPSPPPRRR-----SPSPRRYSPPIQRRYSPSPPPKRRTASPP 618

Query: 481 ----RGVSPEGRRPPVVVNLSTSP----RRYAALSLSETSLTEKGRAGEGLGRNWYVTPE 532
               R  SP    PP    +S SP    R          SL+ K R G    R+   T E
Sbjct: 619 PPPKRRASPS---PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRS---TRE 672

Query: 533 ITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSR 592
                 + R +  P  RA   P   + PPP       +  R++S       I  +   SR
Sbjct: 673 ARSPQPNKRHSPSPRPRA---PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRV---SR 726

Query: 593 PTAGQASEPAADCLGPQLRRLLDSRP-AGSGAPALAPPRSPPASAGSAE-----EPAAPG 646
               +  + AA      +RR+  SR  +GS  PA   P +PP+   S        PA P 
Sbjct: 727 TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPV 786

Query: 647 EAADA---SPEPSADED 660
           + A +   SP P  + D
Sbjct: 787 KKAKSPTPSPSPPRNSD 803



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 132/527 (25%), Positives = 173/527 (32%), Gaps = 140/527 (26%)

Query: 23  PGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRART 82
           P P  + SP  R+  R   P P   RH RS                      S V R R 
Sbjct: 315 PSPRRRPSPRRRTPPRRMPPPP---RHRRS---------------------RSPVRRRRR 350

Query: 83  REA------EPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRR--EP 134
             A           +RS+S P+ PP  T   +SPP      R+ +R + + + PRR   P
Sbjct: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRT---SSPP------RKTRRLSPSASPPRRRHRP 401

Query: 135 AYPALRALANELHPIKLQPQRG-------GPGRVAPLCAAAGRCAPPEPPAGPAPHVRCR 187
           + PA         P   Q  R         PGR +            E P+ PAP     
Sbjct: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS-PAP----- 455

Query: 188 LDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCA 247
              KP    L  +       G   AA   +   Q+        R    S + + S S   
Sbjct: 456 ---KPRKVELSESEEDKG--GKMAAADSVQQRRQYR-------RQNQQSSSDSGSSSSSE 503

Query: 248 D---PRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDA 304
           D    R+   +G +   R ++  RS      P P +      P+G R   + SP PT   
Sbjct: 504 DERPKRSHVKNGEVGRRRRHSPSRS----ASPSPRKRQKETSPRG-RRRRSPSPPPTRRR 558

Query: 305 YYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEE 364
             P P        P PRR         R  P   P  RS    +PR Y  P   RY P  
Sbjct: 559 RSPSP-------APPPRRRRTPTPPPRRRTPSPPPRRRS---PSPRRYSPPIQRRYSPSP 608

Query: 365 PRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPP----SDP 420
           P    TA P                   P  R+SP+     P P R +   PP    S P
Sbjct: 609 PPKRRTASP----------------PPPPKRRASPS-----PPPKRRVSHSPPPKQRSSP 647

Query: 421 -----DPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGP-RREDPLGRGRSYENLLG 474
                 P L+S H   G+SP R   ++R          +P P +R  P  R         
Sbjct: 648 VTKRRSPSLSSKH-RKGSSPSRSTREAR----------SPQPNKRHSPSPR--------- 687

Query: 475 REVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGE 521
                PR        PPV    S+SP+R  + S S   +    R  E
Sbjct: 688 -----PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 729



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 17/54 (31%), Positives = 24/54 (44%), Gaps = 8/54 (14%)

Query: 826 PPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPP 879
           PP     P+P PR   P+ R+++       SP+ PP  R+  P        PPP
Sbjct: 575 PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP--------PPP 620


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 148/629 (23%), Positives = 203/629 (32%), Gaps = 110/629 (17%)

Query: 62   PAMETLPEPPPPESA--VPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGRE 119
            P  E  P  PPPE++   P      A P   A   S P     L+P P   P+ P    E
Sbjct: 451  PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP--PPE 508

Query: 120  AQRAARAEASPRREP-AYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPA 178
            +   +  E SP   P   P   AL   L P         P   +PL        P E P 
Sbjct: 509  SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP-----PPEELPT 563

Query: 179  GPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARP-------APQFHGLTVPGPR 231
             P P    RL   P+++ +      S    P EA+    P        P       P P 
Sbjct: 564  SPPPEA-SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622

Query: 232  HMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTT--PPGPTQFFYTEEPQG 289
               LS  P P DS  + P     + P+  P + +    LP  +   P P +   +  P+ 
Sbjct: 623  ASRLS--PPPEDSPMSPPPE---ESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE- 676

Query: 290  FRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGE-- 347
                   SP P      P P  S     P            + + P++E P      E  
Sbjct: 677  ---ESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ 733

Query: 348  -APRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGP 406
              PR+ G    PR  PEEP  H + RP                   PH           P
Sbjct: 734  LCPRSEGPHLSPR--PEEP--HLSPRP-----------------EEPHLSPQAEEPHLSP 772

Query: 407  RPYRTLQVVPPSDPDPLLASWHGGTGTSPP------RLATDSRHYSR-SWDNILAP---- 455
            +P        P +P   L+    G   SP          T+  H S    +  L+P    
Sbjct: 773  QPEEPCLCAVPEEPH--LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830

Query: 456  ---GPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALS----- 507
                P+ E+P    R  E+ L  E+ +P  +SP   +PP       +P            
Sbjct: 831  SHLSPQSEEPCLSPRPEESHLSPELEKP-PLSPRPEKPPEEPGQCPAPEELPLFPPPGEP 889

Query: 508  -----LSETSLTEKGRAGEGLGRNWYVTPEITITDND--LRATERPSARAWELPGGRTRP 560
                 L E +L+E G             P ++    +  L  +  PS     +P     P
Sbjct: 890  SLSPLLGEPALSEPGE------------PPLSPLPEELPLSPSGEPSLSPQLMP-----P 932

Query: 561  PPHAAPDGP--TSGRQRSLEQLDELITDLVIDSRPTAGQA-SEPAADCLGPQLRRLLDSR 617
             P   P  P  T+    +L  L EL         P   +  S+P +    P L   +   
Sbjct: 933  DPLPPPLSPIITAAAPPALSPLGEL-------EYPFGAKGDSDPESPLAAPILETPISPP 985

Query: 618  P-AGSGAPALAPPRSPPASAGSAEEPAAP 645
            P A    P   PP   P S GS   PA+P
Sbjct: 986  PEANCTDPEPVPPMILPPSPGSPVGPASP 1014



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 109/470 (23%), Positives = 152/470 (32%), Gaps = 90/470 (19%)

Query: 38   RPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRARTREA-EPRRRARSKSA 96
            +P+ P PF K  C S D L   + P +       P  S  P   +R+A E ++     S+
Sbjct: 2237 QPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASS 2296

Query: 97   PR-APPGL------------------TPAPASPPVLPRRGREAQRAARAEASPRREPAYP 137
            P   PP L                  TP     P+ PR  +   ++      P+  P   
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQ 2356

Query: 138  ALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPE-----PPAGPAPHVRCRLDIKP 192
            AL A +   HP   +P         P      +  PPE     PP         R+   P
Sbjct: 2357 AL-APSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASP 2415

Query: 193  DDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAF 252
                 Q +++   +  P  A  +  P+P       P P     SR P+   S   DP A 
Sbjct: 2416 QS---QSSSQSPLTPRPLSAEAFC-PSPVTPRFQSPDP----YSRPPSRPQS--RDPFAP 2465

Query: 253  YCDGPLPGPRDYAERR-----------SLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPT 301
                P P P + A +              P   P GP    + + P G   +F  SPG  
Sbjct: 2466 LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGT- 2524

Query: 302  FDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPS--RSYYGEAPRAYGLPYGPR 359
              A+   P P   +    P+ +G          P   PP    S++G  P   G P    
Sbjct: 2525 -GAFVGTPSP---MRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGP-TLGKPQSTN 2579

Query: 360  YVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSD 419
            Y       H +  P                     P S      +G  P R   V+PP  
Sbjct: 2580 YTVATGNFHPSGSPL-------------------GPSSGSTGESYGLSPLRPPSVLPPPA 2620

Query: 420  PDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDP-LGRGRS 468
            PD  L           P L+    H +     I +P  +REDP  G G S
Sbjct: 2621 PDGSL-----------PYLS----HGASQRSGITSPVEKREDPGTGMGSS 2655



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 169/714 (23%), Positives = 229/714 (32%), Gaps = 142/714 (19%)

Query: 6    PPDLLVSTVYQDIKVATPGPASKCSPC--ERSVARPAEPAPFNKRHCRSFDFLEALDGPA 63
            P +L  S + + + ++ P   S  SP   E  ++ P E +PF+                 
Sbjct: 471  PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP---------------- 514

Query: 64   METLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTP----APASPPVLPRRGRE 119
            +E  P  PP ES    A      P   A   S P     L+P     P SPP  P   R 
Sbjct: 515  LEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP--PEASRL 572

Query: 120  AQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLC--AAAGRCAPP--- 174
            +     +  SP  E +  +    A+ L P   +     P   +PL     A R +PP   
Sbjct: 573  SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED 632

Query: 175  --------EPPAGPAPHVR--------CRLDIKPDDAVLQHATRGSRSCGPTEAAHWARP 218
                    E P  P P V          RL   P+++ L      S +  P EA+  + P
Sbjct: 633  SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLS-P 691

Query: 219  APQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTP--- 275
             P+    T P P     S  P P DS  + P       PLP       R   P  +P   
Sbjct: 692  PPE-DSPTSPPPEDSPAS--PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748

Query: 276  -----PGPTQFFYTEEPQGFRGSFAASP-GPTFDAYYPRPYPSEELSGP--SPRRMGGYY 327
                 P P +   +  PQ      +  P  P   A    P+ S +  GP  SP+      
Sbjct: 749  EPHLSPRPEEPHLS--PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQ------ 800

Query: 328  AGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDV 387
              E+   P  E P  S   E P     P      P+      + RP          E+  
Sbjct: 801  PEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP-EESHLSPELEKPP 859

Query: 388  LARTYPHPRSSPAWADWGPRPYRTLQVVPPSDP--DPLLASWHGGTGTSPPRLATDSRHY 445
            L+   P P   P      P P       PP +P   PLL          PP         
Sbjct: 860  LS---PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP--------- 907

Query: 446  SRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAA 505
                   L+P P  E PL          G     P+ + P+   PP+      SP   AA
Sbjct: 908  -------LSPLP-EELPLSPS-------GEPSLSPQLMPPDPLPPPL------SPIITAA 946

Query: 506  LSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAA 565
               +  +L+  G      G      PE  +           +A   E P     PPP A 
Sbjct: 947  ---APPALSPLGELEYPFGAKGDSDPESPL-----------AAPILETP---ISPPPEAN 989

Query: 566  PDGPTSGRQRSLEQLDELITDLVIDSRP--TAGQASEPAADCLGPQLRRLLDSRPAGSGA 623
               P            E +  +++   P    G AS    + L PQ   LL      S  
Sbjct: 990  CTDP------------EPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH----SLV 1033

Query: 624  PALAPPR--SPPASAGSAEEPAAP-GEAADASPEPSADEDDLMTCSNARCRRTE 674
            P  +PP   SPPA   S   P +P G+    S E    E +    S   C   E
Sbjct: 1034 PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE 1087



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 85/369 (23%), Positives = 123/369 (33%), Gaps = 77/369 (20%)

Query: 60   DGPAMETLPEPPPPESAVPR------ARTREAEPRRRARSKSAPRAPPGLTP------AP 107
            D P    L  PP   + VP       A     EPR        P APP   P      AP
Sbjct: 2154 DSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPR-------FPTAPPTYPPYPSPTGAP 2206

Query: 108  ASPPVL-----PRRGREAQRAARAEASPRREPAY--PALRALANELHPIKLQPQRGGPGR 160
            A PP+L     P  G+  +       +PR +P+   P L+     L  + + P+  G G 
Sbjct: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV-PESPGVG- 2264

Query: 161  VAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAP 220
                    G+ + P     P    R  L++K ++         S S GP        P+ 
Sbjct: 2265 -------GGKASEPLLSPPPFGESRKALEVKKEE-----LGASSPSYGPPNLGFVDSPSS 2312

Query: 221  QFH--GLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPG----PRDYAERRSLPFTT 274
              H  GL +  P       T          PRA   +   PG    P++    ++L  + 
Sbjct: 2313 GTHLGGLELKTPDVFKAPLT----------PRASQVEPQSPGLGLRPQEPPPAQALAPSP 2362

Query: 275  PPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTF 334
            P  P  F     P  +   +A  P        P+P P E      PR +       V   
Sbjct: 2363 PSHPDIF----RPGSYTDPYAQPPLTP----RPQPPPPESCCALPPRSLPSDPFSRVPAS 2414

Query: 335  PIQEPPSRSYYGEAPRAYGL----PYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLAR 390
            P  +  S+S     P +       P  PR+   +P +   +RP         + RD  A 
Sbjct: 2415 PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP---------QSRDPFAP 2465

Query: 391  TYPHPRSSP 399
             +  PR  P
Sbjct: 2466 LHKPPRPQP 2474



 Score = 33.5 bits (75), Expect = 1.00
 Identities = 29/90 (32%), Positives = 33/90 (36%), Gaps = 2/90 (2%)

Query: 805 LYEPAECFLLSVSVAVGPGTAPPGT-PALPAPAPRSHGPTVRKFAKVALAAGSPARPPPA 863
           L  P E   LS      P + PP   P  P P      P   +         SP  PPP 
Sbjct: 536 LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595

Query: 864 RSRE-PDMETLILTPPPGTAGLDQDGEAGR 892
            SR  P  E   L+PPP  + L    EA R
Sbjct: 596 ASRLFPPFEESPLSPPPEESPLSPPPEASR 625



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 91/389 (23%), Positives = 133/389 (34%), Gaps = 55/389 (14%)

Query: 291  RGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPR 350
            RG+F +   PT   YY +      LS P              T P   PP+     +   
Sbjct: 4592 RGAFGSGALPTGPDYYSQLLTKNNLSNPP-------------TPPSSLPPTPPPSVQQKM 4638

Query: 351  AYGLPYGPRYVPEEPRAHSTARPF--YTEDFGRYRERDVLAR--TYPHPRSSPAWADWGP 406
              G+      + E P+  ++AR       D    +  D+LA   T PH ++     +   
Sbjct: 4639 VNGVTPSEE-LGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDE 4697

Query: 407  RPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPG----PRREDP 462
                   +VP S P+ +L       G   PR            D  L+P     PR   P
Sbjct: 4698 DSDSPDSIVPASSPESIL-------GEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIP 4750

Query: 463  LGRGRSYENLLGREV--REPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAG 520
            +         LG EV  + P     +G+   V V L+ S    AA +L+   +       
Sbjct: 4751 VFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAA--AAKNLNGVMVA----VA 4804

Query: 521  EGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPD-GPTSGRQRSLEQ 579
            E L      + E+   ++  RA   P     E PGG+ +     +PD GP       L+Q
Sbjct: 4805 ELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPD-----WLKQ 4859

Query: 580  LDELITDLVIDSR-------PTAGQASEPAADCLGPQLRRLLDSRPAGSGAP-ALAPPRS 631
             D ++    + S+            A EP            LD R   +  P   +PP S
Sbjct: 4860 FDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS 4919

Query: 632  P--PASAGSAEEPAA--PGEAADASPEPS 656
            P  P+ A    EP    P E     P PS
Sbjct: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPS 4948



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 31/121 (25%), Positives = 41/121 (33%), Gaps = 19/121 (15%)

Query: 61   GPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREA 120
            GPA   L EP PP+ +          P+    S+ +P A P   P+P SP        + 
Sbjct: 1010 GPASPILMEPLPPQCS--PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDE 1067

Query: 121  QRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP 180
                  E     EP  PAL                  P   +PL +  G  + P P   P
Sbjct: 1068 AELHEMETEKVSEPECPALE-----------------PSATSPLPSPMGDLSCPAPSPAP 1110

Query: 181  A 181
            A
Sbjct: 1111 A 1111



 Score = 30.4 bits (67), Expect = 8.4
 Identities = 25/92 (27%), Positives = 33/92 (35%), Gaps = 10/92 (10%)

Query: 68   PEPPPPESAVPRARTREAEPRRRARSKSAPRAPPG-LTPAPASPPVLPRRGREAQRAARA 126
            PEPP   S        +   +  A     P  PP  L P+PASPP  P            
Sbjct: 4886 PEPPTQHSYTYNVSNLDVR-QLSAPPPEEPSPPPSPLAPSPASPPTEP--------LVEL 4936

Query: 127  EASPRREPAYPALRALANELHPIKLQPQRGGP 158
               P  EP  P+   LA+     + +P+   P
Sbjct: 4937 PTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 128/503 (25%), Positives = 165/503 (32%), Gaps = 106/503 (21%)

Query: 224 GLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFY 283
           GL     R       P+ +    + P  F  D    G   Y          P  P   + 
Sbjct: 106 GLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGR------LGPSEPRGIYA 159

Query: 284 TEEPQGFRGSFAASPGPT-FDAYYPR----PYPSEELSGPSPRRMGGYYAGEVRTFPIQE 338
           +E P+    +  ++P      A  PR    PYP+    G +            R  P   
Sbjct: 160 SERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTA--GGSAGPEACSSAERRARAGPFLT 217

Query: 339 P-PSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPF--YTEDFGRYRERDVLARTYPHP 395
           P P  +    +PR  G P       + P A    RP   Y     R R R    R    P
Sbjct: 218 PSPLHAVAMRSPRPCGRP-----PTDSPDAGGAGRPLDGYISALLRRRRR----RGAGQP 268

Query: 396 RSSPAWADWGPRPYRTLQVVPP-SDPDPLLA--------SWHGGTGTSPPRLATDSRHYS 446
           R+SP  AD GPR   +++  PP + P P  A           GG  TSP  L   SR ++
Sbjct: 269 RTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAAL---SRAWA 325

Query: 447 RSWDNILAPGP----------------------------------------RREDPLGRG 466
            SW++  AP P                                        R+  PL RG
Sbjct: 326 SSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRG 385

Query: 467 RSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRN 526
           RS E    RE   PR     GR         +   R A+ S SETSL  +  A    G  
Sbjct: 386 RSVEQSPPRE--RPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPS-GPP 442

Query: 527 WYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQ-RSLEQLDELIT 585
            Y T E        R   RP       P  R  P P  A     S R+ RS  ++D    
Sbjct: 443 KYPTAE--------REEPRP-------PRPRRGPAPTLAAQAAGSCRRWRSTAEID-AAD 486

Query: 586 DLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGS--GAPALAP-PRSPPASA-----G 637
              +  R  A +   P      PQ R L     + S   A  L P  R  PA       G
Sbjct: 487 GRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYG 546

Query: 638 SAEEPAAPGEAADASPEPSADED 660
            +E  A+ GE + A    S+D D
Sbjct: 547 ESESSASEGE-SPAFSSASSDSD 568



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 44/133 (33%), Positives = 52/133 (39%), Gaps = 28/133 (21%)

Query: 61  GPAMETLPEPPPPESAVPRARTREAEPRR---RARSKSAPRAPPGL----TPAPASPPVL 113
           G ++E  P    P +A  R R  EA  RR   RAR  S  ++   L    +  P+ PP  
Sbjct: 385 GRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKY 444

Query: 114 PRRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGR----VAPLCAAAG 169
           P   RE  R  R    PRR PA P L A            Q  G  R     A + AA G
Sbjct: 445 PTAEREEPRPPR----PRRGPA-PTLAA------------QAAGSCRRWRSTAEIDAADG 487

Query: 170 RCAPPEPPAGPAP 182
           R   P  PA   P
Sbjct: 488 RRVRPRAPAARVP 500



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 68/258 (26%), Positives = 91/258 (35%), Gaps = 75/258 (29%)

Query: 22  TPGPASKCSPCERSVA-RP--AEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVP 78
           +PG A      + SV  RP  A P+P + R  R          P++E +   P   +A+ 
Sbjct: 271 SPGGADGGPRRQNSVRQRPPDASPSPGSARPARE---------PSLERVGGHPTSPAALS 321

Query: 79  RARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGR--EAQRAARAEASPR----- 131
           RA     E      S++AP   P   PA  SPP  P  GR  +AQ    A+A+ R     
Sbjct: 322 RAWASSWE------SEAAPE--PAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGR 373

Query: 132 --REPAYPALRALANELHPIKLQPQRGG-PGRVA--------PLCAAAGRC--------- 171
             R    P  R  + E  P + +P+  G  GR+A        P    A R          
Sbjct: 374 AARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGR 433

Query: 172 -------------------APPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEA 212
                               PP P  GPAP +          A    + R  RS    +A
Sbjct: 434 ASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLA---------AQAAGSCRRWRSTAEIDA 484

Query: 213 AHWARPAPQFHGLTVPGP 230
           A   R  P+     VPGP
Sbjct: 485 ADGRRVRPRAPAARVPGP 502


>gi|239755710 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 402

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 72/261 (27%), Positives = 98/261 (37%), Gaps = 38/261 (14%)

Query: 68  PEPPPPESAVPRARTREAEPRRRAR---SKSAPRAPPGLTPAPASPPVLPRRGREAQRAA 124
           P P  P++        +A  R R +   S ++PR  PG     A+  V P  G+  +  +
Sbjct: 111 PGPCAPQALASLLGPGKAGCRTRLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTS 170

Query: 125 RAEASPRREPAYPALRALANELHPIKL---------QPQRGGPGRVAPLCAAAGRCAPPE 175
            A+AS  R    P L   +  L P++L          P   GPGR+      + +  PP 
Sbjct: 171 LAQAS--RSGTVPGLPPAS--LQPLRLPYLAPPGPHDPTSRGPGRLLTCEPPSRKLPPPL 226

Query: 176 PPA------GPAPHVRCRLDIKPDDAVLQHAT--RGSRSCGPTEAAHWARPAPQFHGLTV 227
           PP        P P VR RL +      L+ A   RGSR+     A    R A     LT+
Sbjct: 227 PPCRSRWVLAPPPTVRPRLRVLTPPLALRRALPERGSRTPSTRSAVLSGRVAGLGTELTL 286

Query: 228 PGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEP 287
                 A    P  S+   A  RAF    PLP P  +    SLP     G        +P
Sbjct: 287 TPSSRRAHGSHPLSSERQAAPTRAFCSADPLPRPPSFVP--SLPSPQAQGQA----VRQP 340

Query: 288 QGFRGSFA--------ASPGP 300
           +  R + A         SPGP
Sbjct: 341 RLLRAALALGAPRGRTPSPGP 361


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 78/313 (24%), Positives = 105/313 (33%), Gaps = 49/313 (15%)

Query: 66  TLPEPPPPESAVPRARTREAEPRRRARSKSA---PRAPPGLTPAPASPPVLPRRGREAQR 122
           T P   PP  A P  +   + P     S SA   P+APP L   P      P +   A  
Sbjct: 465 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524

Query: 123 AARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP-- 180
               +A P    ++P  +A  +    + + P    P +  P+ AA     PP PPA P  
Sbjct: 525 TPPLQALPSPPASFPG-QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583

Query: 181 -APH-------------VRCRLDIKPDDAVLQHATRGSRSCGPTEAAHW--ARPAPQFHG 224
            AP               R  L + P        +  S   GP  A H   A   P+   
Sbjct: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643

Query: 225 LTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPP-------- 276
               GP   A +  P  ++     P A +  GP P P  +      P   PP        
Sbjct: 644 GYDSGPEGGAAASPPPDAELAACHPAA-WSRGPAP-PLAFRGAPGAPLPWPPATGPGSAD 701

Query: 277 GPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPI 336
           G    + TE P+      +A+P P   A  P         GPSP   GG  A        
Sbjct: 702 GLCTIYETEGPE------SATPAP--GALDP---------GPSPGTSGGKAAAGAGAGAS 744

Query: 337 QEPPSRSYYGEAP 349
              P ++  GE P
Sbjct: 745 SRSPKQARLGELP 757



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 161/699 (23%), Positives = 216/699 (30%), Gaps = 139/699 (19%)

Query: 19  KVATPGPASKCSPCERSVARPAEPAPFNKRHCR-----SFDFLEALDGPAMETLPEPPPP 73
           K  +PGP S  SP   S      P P  ++  R     +    +A + P    L      
Sbjct: 107 KNTSPGPVS--SPGRASGT--TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162

Query: 74  ESAVPRARTREAEPRRRARSKSA----PRAPPGLTPAPASPPVLPRRG-REAQRAARAEA 128
           +++ P   T      RR+R+       PR  P   P P  P   PR+    A   +  E 
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEP 220

Query: 129 SP--RREPAY------PALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP 180
           SP  RR P+       PA R+L++   P+   P R GP       +A G    P  P+ P
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLS-SPARSGP-------SARGTPRAPAHPSQP 272

Query: 181 APHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPT 240
            P     L       V       + + GP  ++  A P+P      +       L  TP 
Sbjct: 273 KPK---GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP---SAALQSQAPPTLPATPH 326

Query: 241 PSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGP 300
            S   C          P P      +    P  TPP                +  +   P
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ--------------ATTSLGSP 372

Query: 301 TFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRY 360
           T  A +    PS  LS                  P+  PP      +AP A  LP  P  
Sbjct: 373 TLQATHSF-LPSPPLS------------------PLATPPP-----QAPPALALP--PLQ 406

Query: 361 VPEEPRAHSTARPFYTEDFGRYRERDV--LARTYPHPRSSPAWADWGP--RPYRTLQVVP 416
            P  P A     P  T          V  L   +  P S P  A + P   P  +    P
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466

Query: 417 PSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGRE 476
           PS   P LA        +PP     S   S        P P+   PL            +
Sbjct: 467 PSQAPPSLA--------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-------PLQ 511

Query: 477 VREPRGVSPEGRRPPVVVNLSTSPRRY---------AALSLSETSLTEKGRAGEGLGRNW 527
           + +P   +P     P +  L + P  +         A+L +S  + T   +A   L    
Sbjct: 512 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA-TPPPQAPPVLAAPL 570

Query: 528 YVTPEITITDNDLRATERPSARAWELPGGRTR----------PPPHAAPDGPTSGRQRSL 577
              P        L+A  RP     +      R          PPP  +P    SG   + 
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630

Query: 578 EQLDELITDLVI---DSRPTAGQASEPAADCLGPQLRRLLDSR-PA-------GSGAPAL 626
                  T   +   DS P  G A+ P  D           SR PA         GAP  
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 690

Query: 627 APPRSPPASA----------GSAEEPAAPGEAADASPEP 655
            PP + P SA          G      APG A D  P P
Sbjct: 691 WPPATGPGSADGLCTIYETEGPESATPAPG-ALDPGPSP 728



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 66/262 (25%), Positives = 90/262 (34%), Gaps = 37/262 (14%)

Query: 406 PRPYRTLQVVPPSDPDPL-LASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLG 464
           PRP  + +  PP  P  L +    G  G  P       R        I    PR      
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKP----LAERAGGIGGATIPESAPRAGPTRS 82

Query: 465 RGRSYENLLGREVREPRGVSPEGRRPPVVVNLS----TSPRRYAA-----------LSLS 509
            G S  N   R     RG      R P   N S    +SP R +            L +S
Sbjct: 83  AGTSSRNPASRPPASGRG-----ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137

Query: 510 ETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPS----ARAWELPGGRTRPPPHAA 565
                 +G+A E   R+         T      T  P+    +RA     G  RP P A 
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197

Query: 566 PDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPA 625
           P  PT G ++S+    E  T     + P+      P+A   G  L+R      + S  P 
Sbjct: 198 PRPPTEGPRKSVSSASEHST-----TEPSPAARRRPSA---GGGLQRPASRSLSSSATPL 249

Query: 626 LAPPRSPPASAGSAEEPAAPGE 647
            +P RS P++ G+   PA P +
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQ 271



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 95/377 (25%), Positives = 126/377 (33%), Gaps = 83/377 (22%)

Query: 311 PSEELSGPSPRRMGGYYAGEVRTFPI---------QEPPSRSYYGEAPRAYGLPYGPRYV 361
           P  + + P P    G  +G  R  P+         +E  +R    EAP+   L  G R  
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 163

Query: 362 PEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWG-PRPYRTLQVVPPSD- 419
              P    T  P              +AR     RS  A  + G PRP  + +  PP++ 
Sbjct: 164 TSGPTP-GTPSP-------------AMAR-----RSRAAGTEVGLPRPAPSARPRPPTEG 204

Query: 420 --PDPLLASWHGGTGTSPPRLATDS------RHYSRSWDNILAP--GPRREDPLGRGRSY 469
                  AS H  T  SP      S      R  SRS  +   P   P R  P  RG   
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP- 263

Query: 470 ENLLGREVREPRGVSPEGR---RPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRN 526
                R    P    P+G    RPP V    T PR+ AA +L   S +            
Sbjct: 264 -----RAPAHPSQPKPKGLQALRPPQV----TPPRKDAAPALGPLSSSPLATPSPSAALQ 314

Query: 527 WYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITD 586
               P +  T +    T      A  LP     PP  +AP         SL+ L      
Sbjct: 315 SQAPPTLPATPHSSSLT---CQLATPLP---LAPPSPSAPP--------SLQTLPS---- 356

Query: 587 LVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAP-ALAPPRSPPASA-----GSAE 640
                 P A   S+       P L+      P+   +P A  PP++PPA A         
Sbjct: 357 ------PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410

Query: 641 EPAAPGEAADASPEPSA 657
            PA+P  +  A+P P A
Sbjct: 411 PPASPPLSPLATPSPQA 427



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 142/605 (23%), Positives = 185/605 (30%), Gaps = 146/605 (24%)

Query: 96  APRAPPGLTPAPAS-----PPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIK 150
           A RAP  LTP P       PPV P   R    A      P  E A     A   E  P  
Sbjct: 18  AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP-- 75

Query: 151 LQPQRGGPGRVA----------PLCAAAGRCAPPEPPAGPAP---HVRCRLDIKPDDAVL 197
               R GP R A          P  +  G  APP     P P     R     +P     
Sbjct: 76  ----RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL-- 129

Query: 198 QHATRGSR-SCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDG 256
               +G R S   T A   A  AP+   L+    R  +     TPS +     RA   + 
Sbjct: 130 --GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187

Query: 257 PLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELS 316
            LP P   A  R      PP       TE P+  +   +AS   T +     P P+   +
Sbjct: 188 GLPRPAPSARPR------PP-------TEGPR--KSVSSASEHSTTE-----PSPA---A 224

Query: 317 GPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPE-EPRAHSTARPFY 375
              P   GG      R+      P  S     P A G P  P +  + +P+     RP  
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-- 282

Query: 376 TEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSP 435
                              P+ +P   D  P     L   P + P P  A        +P
Sbjct: 283 -------------------PQVTPPRKDAAP-ALGPLSSSPLATPSPSAAL----QSQAP 318

Query: 436 PRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVN 495
           P L   + H S     +  P P                           P    PP +  
Sbjct: 319 PTLPA-TPHSSSLTCQLATPLPL------------------------APPSPSAPPSLQT 353

Query: 496 LSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDL-------RATERPSA 548
           L + P             T   +A   LG     +P +  T + L        AT  P A
Sbjct: 354 LPSPP------------ATPPSQATTSLG-----SPTLQATHSFLPSPPLSPLATPPPQA 396

Query: 549 -RAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVID-------SRPTAGQASE 600
             A  LP  +  P P A+P  P S       Q    +   ++        S P     S 
Sbjct: 397 PPALALPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454

Query: 601 PAADCLGPQLRRLLDSRPAGSGAPAL---APPRSPPASAGSAEEPAAPGEAAD-----AS 652
           PA+  + P       + P+ +  P     +PP SPP S  +   P AP   A      A 
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514

Query: 653 PEPSA 657
           P P A
Sbjct: 515 PPPQA 519



 Score = 33.9 bits (76), Expect = 0.76
 Identities = 63/246 (25%), Positives = 82/246 (33%), Gaps = 29/246 (11%)

Query: 92  RSKSAPRAPPGLTPA---------PASPPVLPRRGREAQRAARAEASPRREPAYPALRAL 142
           R   +PR PP +TPA               L  R      A   E++PR   A P   A 
Sbjct: 28  RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR---AGPTRSAG 84

Query: 143 ANELHPIKLQPQRGGPGRVAPL-CAAAGRCAPPEPPAG---PAPHVRCRLDIKPDDAVLQ 198
            +  +P    P  G   R  P    + G  + P   +G   P P  +  L I  ++ V  
Sbjct: 85  TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV-- 142

Query: 199 HATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPL 258
              RG  +  P  +A  A       G T PG    A++R    + +    PR      P 
Sbjct: 143 --ARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199

Query: 259 P---GPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEEL 315
           P   GPR      S   TT P P        P    G     P     +    P  S   
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAA---RRRPSA--GGGLQRPASRSLSSSATPLSSPAR 254

Query: 316 SGPSPR 321
           SGPS R
Sbjct: 255 SGPSAR 260


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 92/338 (27%), Positives = 116/338 (34%), Gaps = 65/338 (19%)

Query: 27  SKCSP-----CERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRAR 81
           ++C P     C R    P+ P    +RHCR               LP+PPP +      R
Sbjct: 144 ARCLPRSVGSCVRPSVGPSLPRRHCRRHCRCH--------CRRRPLPKPPPLQ-----PR 190

Query: 82  TREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRA 141
              A P R A   +  RA P L+P        PRR R      RAE SP      P  R+
Sbjct: 191 LGSASPPRLAAPLAGSRA-PSLSP-------FPRRCRR-----RAERSPAGH-GLPLPRS 236

Query: 142 LANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHAT 201
           L+     +  + +RGG  R             P  PAGPA          P  A  + A 
Sbjct: 237 LSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPA---------APGRAGERRAA 287

Query: 202 R--GSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADP-RAFYCDGP- 257
           R    R  GP  +           G   P  R  +    P+P+      P RA +  GP 
Sbjct: 288 RQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPR 347

Query: 258 LPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSG 317
           L  P   AE        P G T    T EP   R + A S G        R  PS     
Sbjct: 348 LSAPSAEAEE------VPGGHTASNPTYEPLSSRRTKAPSEG--------RDSPS----- 388

Query: 318 PSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLP 355
            SP     Y   E     +   PSRS Y  +P +  +P
Sbjct: 389 -SPATSTHYLDRESGLGSVNSHPSRSPYNWSPPSPSVP 425



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 85/317 (26%), Positives = 97/317 (30%), Gaps = 62/317 (19%)

Query: 68  PEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAE 127
           P P  PE A     T    P   A      RAPP + PAP  PP   R    A  AA A 
Sbjct: 14  PAPGCPEVAPQPEGTDAPGP---AVCSPTARAPPPILPAPQRPPTRAREWEGAAWAAGAT 70

Query: 128 ASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCR 187
                  A P  R L     P+  +    GP   AP   A G C        P P  R  
Sbjct: 71  GVGAALLALPGSRRLGRV--PLTFREASPGPAPGAP--RARGSCG-----REPGPRRR-- 119

Query: 188 LDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCA 247
                         R   S G   AA  AR AP         PR  +L+R    S   C 
Sbjct: 120 --------------RAPSSAGKRPAAA-ARAAP---------PRQRSLARCLPRSVGSCV 155

Query: 248 DPRAFYCDGPLPGPRDYAER------RSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPT 301
            P      GP   PR +  R      R  P   PP       +  P       A S  P+
Sbjct: 156 RPSV----GP-SLPRRHCRRHCRCHCRRRPLPKPPPLQPRLGSASPPRLAAPLAGSRAPS 210

Query: 302 FDAYYPRPYPSEELSG-----PSPRRM--GGYYAGEVRTFPIQEPPSRSYYGEAPRAYGL 354
              +  R     E S      P PR +  GG   G  R    +E   R       R  G 
Sbjct: 211 LSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRG------RRQGC 264

Query: 355 PYGPRYVPEEPRAHSTA 371
             G   +P  P A   A
Sbjct: 265 ALGSPPIPAGPAAPGRA 281


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 78/313 (24%), Positives = 105/313 (33%), Gaps = 49/313 (15%)

Query: 66  TLPEPPPPESAVPRARTREAEPRRRARSKSA---PRAPPGLTPAPASPPVLPRRGREAQR 122
           T P   PP  A P  +   + P     S SA   P+APP L   P      P +   A  
Sbjct: 426 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 485

Query: 123 AARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP-- 180
               +A P    ++P  +A  +    + + P    P +  P+ AA     PP PPA P  
Sbjct: 486 TPPLQALPSPPASFPG-QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 544

Query: 181 -APH-------------VRCRLDIKPDDAVLQHATRGSRSCGPTEAAHW--ARPAPQFHG 224
            AP               R  L + P        +  S   GP  A H   A   P+   
Sbjct: 545 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604

Query: 225 LTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPP-------- 276
               GP   A +  P  ++     P A +  GP P P  +      P   PP        
Sbjct: 605 GYDSGPEGGAAASPPPDAELAACHPAA-WSRGPAP-PLAFRGAPGAPLPWPPATGPGSAD 662

Query: 277 GPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPI 336
           G    + TE P+      +A+P P   A  P         GPSP   GG  A        
Sbjct: 663 GLCTIYETEGPE------SATPAP--GALDP---------GPSPGTSGGKAAAGAGAGAS 705

Query: 337 QEPPSRSYYGEAP 349
              P ++  GE P
Sbjct: 706 SRSPKQARLGELP 718



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 85/333 (25%), Positives = 110/333 (33%), Gaps = 52/333 (15%)

Query: 62  PAMETLPEPP--PPESAVPR--ARTREA------EPRRRARSKSAPRAPPGLT------- 104
           P+++TLP PP  PP  A     + T +A       P     +   P+APP L        
Sbjct: 310 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 369

Query: 105 -PAPASPPVLPRRGREAQR----AARAEASPRREPAYPALRALANELHPIKLQPQRGGPG 159
              PASPP+ P      Q     A     +P   P  P ++A  +      + P    P 
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429

Query: 160 RVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPA 219
           +  P  AA     PP PPA P           P  A    A    +   P   A  A   
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSA---TPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486

Query: 220 PQFHGLTVPGPRHMALSRTP-TPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGP 278
           P    L  P P      + P +PS S    P A     P   P   A    +P + P  P
Sbjct: 487 PPLQAL--PSPPASFPGQAPFSPSASLPMSPLA--TPPPQAPPVLAAPLLQVPPSPPASP 542

Query: 279 TQFFYTEEP--------QGFRGSFAASPGPTFDAYYPRPYPSEELSGP-----------S 319
           T       P         G R + A +PGP      P   PS  LSGP           +
Sbjct: 543 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP---PSRSPSSTLSGPDLAGHSSSATST 599

Query: 320 PRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAY 352
           P  + GY +G         PP        P A+
Sbjct: 600 PEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 159/655 (24%), Positives = 205/655 (31%), Gaps = 108/655 (16%)

Query: 73  PESAVPRARTREAEPRRRARSKSAPRA---PPGLTPAPASPPVLPRRGREAQRAAR--AE 127
           PESA     TR + P    R + AP A    PG   +P       R G   Q+  R  AE
Sbjct: 71  PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130

Query: 128 ASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPP-AGPAPHVRC 186
            +  R  A  A +  A      +       PG  +P  A   R A  E     PAP  R 
Sbjct: 131 ETVARGKATEAPKRSALSA-GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189

Query: 187 RLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQF-HGLTVPGPRHMALSRTPTPS--- 242
           R    P     + +   +     TE +  AR  P    GL  P  R ++ S TP  S   
Sbjct: 190 R----PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245

Query: 243 --DSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPP--------GPTQFFYTEEPQGFRG 292
              S    PRA       P P+     R  P  TPP        GP        P     
Sbjct: 246 SGPSARGTPRA-PAHPSQPKPKGLQALRP-PQVTPPRKDAAPALGPLSSSPLATP----- 298

Query: 293 SFAASPGPTF-DAYYPRPYPSEELSGPSPRRMGGYYAGEVRTF-------PIQEPPSRSY 344
           S +A P P+   +    P P       +   +G        +F       P+  PP    
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP--- 355

Query: 345 YGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDV--LARTYPHPRSSPAWA 402
             +AP A  LP  P   P  P A     P  T          V  L   +  P S P  A
Sbjct: 356 --QAPPALALP--PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411

Query: 403 DWGP--RPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRRE 460
            + P   P  +    PPS   P LA        +PP     S   S        P P+  
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLA--------APPLQVPPSPPASPPMSPSATPPPQAP 463

Query: 461 DPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRY---------AALSLSET 511
            PL            ++ +P   +P     P +  L + P  +         A+L +S  
Sbjct: 464 PPLAAP-------PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516

Query: 512 SLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTR----------PP 561
           + T   +A   L       P        L+A  RP     +      R          PP
Sbjct: 517 A-TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575

Query: 562 PHAAPDGPTSGRQRSLEQLDELITDLVI---DSRPTAGQASEPAADCLGPQLRRLLDSR- 617
           P  +P    SG   +        T   +   DS P  G A+ P  D           SR 
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635

Query: 618 PA-------GSGAPALAPPRSPPASA----------GSAEEPAAPGEAADASPEP 655
           PA         GAP   PP + P SA          G      APG A D  P P
Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG-ALDPGPSP 689



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 62/248 (25%), Positives = 88/248 (35%), Gaps = 18/248 (7%)

Query: 406 PRPYRTLQVVPPSDPDPL-LASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRRED-PL 463
           PRP  + +  PP  P  L +    G  G  P          +   ++    GP R   P 
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86

Query: 464 GRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGL 523
             GR  E     +   P  VS  GR           P     L +S      +G+A E  
Sbjct: 87  ASGRG-ERAPPAKNTSPGPVSSPGRASGTT---RPGPLGQKGLRISAEETVARGKATEAP 142

Query: 524 GRNWYVTPEITITDNDLRATERPS----ARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQ 579
            R+         T      T  P+    +RA     G  RP P A P  PT G ++S+  
Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202

Query: 580 LDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSA 639
             E  T     + P+      P+A   G  L+R      + S  P  +P RS P++ G+ 
Sbjct: 203 ASEHST-----TEPSPAARRRPSA---GGGLQRPASRSLSSSATPLSSPARSGPSARGTP 254

Query: 640 EEPAAPGE 647
             PA P +
Sbjct: 255 RAPAHPSQ 262



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 92/347 (26%), Positives = 120/347 (34%), Gaps = 54/347 (15%)

Query: 348 APRAYGLPYGPRYVPEE-PRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGP 406
           A RA G+  G   +PE  PRA  T R       GR         T P P SSP  A    
Sbjct: 59  AERAGGI--GGATIPESAPRAGPT-RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115

Query: 407 RPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRG 466
           RP    Q       +  +A    G  T  P+ +  S    R       P P    P    
Sbjct: 116 RPGPLGQKGLRISAEETVAR---GKATEAPKRSALSAGARRDTSG---PTPGTPSPAMAR 169

Query: 467 RSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTE-------KGRA 519
           RS     G EV  PR       RPP      T   R +  S SE S TE       +  A
Sbjct: 170 RS--RAAGTEVGLPRPAPSARPRPP------TEGPRKSVSSASEHSTTEPSPAARRRPSA 221

Query: 520 GEGLGRNWYVTPEITITDNDLRATERPSARAW-ELPGGRTRPPPHAA----PDGPTSGRQ 574
           G GL R    +   + T     A   PSAR     P   ++P P       P   T  R+
Sbjct: 222 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281

Query: 575 RSLEQLDELITDLVIDSRPTA--GQASEPAADCL----------------GPQLRRLLDS 616
            +   L  L +  +    P+A    ++ P+   L                 P L+     
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 341

Query: 617 RPAGSGAP-ALAPPRSPPASA-----GSAEEPAAPGEAADASPEPSA 657
            P+   +P A  PP++PPA A          PA+P  +  A+P P A
Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 92/359 (25%), Positives = 115/359 (32%), Gaps = 59/359 (16%)

Query: 96  APRAPPGLTPAPAS-----PPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIK 150
           A RAP  LTP P       PPV P   R    A      P  E A     A   E  P  
Sbjct: 18  AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP-- 75

Query: 151 LQPQRGGPGRVA-PLCAAAGRCAPPEPPAGPAP---HVRCRLDIKPDDAVLQHATRGSR- 205
               R GP R + P  +  G  APP     P P     R     +P         +G R 
Sbjct: 76  ----RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL----GQKGLRI 127

Query: 206 SCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYA 265
           S   T A   A  AP+   L+    R  +     TPS +     RA   +  LP P   A
Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187

Query: 266 ERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGG 325
             R      PP       TE P+  +   +AS   T +     P P+   +   P   GG
Sbjct: 188 RPR------PP-------TEGPR--KSVSSASEHSTTE-----PSPA---ARRRPSAGGG 224

Query: 326 YYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPE-EPRAHSTARPFYTEDFGRYRE 384
                 R+      P  S     P A G P  P +  + +P+     RP           
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV-------- 276

Query: 385 RDVLARTYPHPRSSPAWADWGPRPYRT-LQVVPPSDPDPLLASWHGGTGTSPPRLATDS 442
                 T P   ++PA       P  T     PPS   P           +PP  AT S
Sbjct: 277 ------TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 121/454 (26%), Positives = 149/454 (32%), Gaps = 86/454 (18%)

Query: 83   REAEPRRRARSKSAPRAPPGLTPAP---------ASPPVLPRRGREAQRAARAEASPRRE 133
            R A+PR  ARS +  R PP   PAP          SPPV PR          +   P   
Sbjct: 629  RRAQPR--ARSSNDARRPPAPQPAPRTLSHWSALLSPPVPPR--------PPSSGPPPAP 678

Query: 134  PAYPALRALANELHPI----KLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLD 189
            P  PAL  L     P     +  P    P  V P    A   A  EPPA  +P V   L 
Sbjct: 679  PLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPP-APQASWWAFVEPPA-VSPEVPPDLL 736

Query: 190  IKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADP 249
              P     + + RGSR  G          A  F G +    R  A S   +P  S  + P
Sbjct: 737  AFPGP---RPSFRGSRRRG---------AAFGFPGASPRASRRRAWSPLASPQPSLRSSP 784

Query: 250  RAFYCDGPLPGPRDYAERRSLPFT---TPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYY 306
               YC  PL  P      R+ PF     PP        E P   R +    P  +     
Sbjct: 785  GLGYC-SPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGS 843

Query: 307  PRPYPSEELS-GPSPRRMGGYYAGEV-RTF-PIQEPPSRSY-------YGEAPR--AYGL 354
            PRP PS  L    SPRR        +  T+  + EPP+R+        +   PR  A+  
Sbjct: 844  PRP-PSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRA 902

Query: 355  PYGPRYVPEEPRAHST------ARPFYTEDF-----------GRYRERDVLARTYPHPRS 397
            P   R  P EP    T        P +  D            G    R   +R  P P  
Sbjct: 903  PLEHRESPREPEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSRRGFSRPPPVP-E 961

Query: 398  SPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGP 457
            +P     GP P  TLQ   P DP                R+     H         + GP
Sbjct: 962  NPFLQLLGPVPSPTLQ---PEDP-----------AADMTRVFLGRHHEPGPGQLTKSAGP 1007

Query: 458  RREDPLGRGRSYENLLGREVREPRGVSPEGRRPP 491
              E P       +  L  E + P    P+   PP
Sbjct: 1008 TPEKPEEEATLGDPQLPAETKPPTPAPPKDVTPP 1041



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 108/451 (23%), Positives = 146/451 (32%), Gaps = 74/451 (16%)

Query: 23   PGPASKCSPCERSVARPAEPAPFNKRH------------CRSFDFLEALDGPAMETLPEP 70
            P PA   SP    + RPA P    +RH                 +   ++ PA+   PE 
Sbjct: 674  PPPAPPLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPPAPQASWWAFVEPPAVS--PEV 731

Query: 71   PPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASP 130
            PP   A P  R      RRR  +   P A P  +   A  P+   +            SP
Sbjct: 732  PPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSP 791

Query: 131  RREPAYPALRALANELHPIKLQPQRGGPGRVAPLCA---AAGRCAPPEPPAGPAPHVRCR 187
               P+ P L        P  L P R  P  +    A   AAGR  PP  P   +P     
Sbjct: 792  LAPPS-PQLSLRTGPFQPPFLPPARR-PRSLQESPAPRRAAGRLGPPGSPLPGSPR---- 845

Query: 188  LDIKPDDAV-LQHATRGSRSCGPTEAAH-WARPAPQFHGLTVPGPRHMALSRTPTPSDSY 245
                P   + L H+ R S    P+   H W R       L+ P  R +     P     +
Sbjct: 846  ---PPSPPLGLCHSPRRSSLNLPSRLPHTWRR-------LSEPPTRAVK----PQVRLPF 891

Query: 246  CADPRAFYCDGPLP---GPRDYAERRSLPFTTPP---------GPTQFFYTEEP--QGFR 291
               PRA     PL     PR+  E    P+T PP          PTQ   +  P   G R
Sbjct: 892  HRPPRAGAWRAPLEHRESPRE-PEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSR 950

Query: 292  GSFAASP----GPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGE 347
              F+  P     P      P P P+ +   P+      +        P Q   S     E
Sbjct: 951  RGFSRPPPVPENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPE 1010

Query: 348  APRAYGLPYGPRYVPEEPRAHSTARPF-------YTEDFGRYRERDVLARTYPHPRSS-- 398
             P        P+ +P E +  + A P         T       E+  L  +  +P ++  
Sbjct: 1011 KPEEEATLGDPQ-LPAETKPPTPAPPKDVTPPKDITPPKDVLPEQKTLRPSLSYPLAACD 1069

Query: 399  ------PAWADWGPRPYRTLQVVPPSDPDPL 423
                  P W  WG  P     + P   P+PL
Sbjct: 1070 QTRATWPPWHRWGTLPQAAAPLAPIRAPEPL 1100



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 107/451 (23%), Positives = 138/451 (30%), Gaps = 72/451 (15%)

Query: 19   KVATPGPASKCSPCERS---VARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPES 75
            K  TP    +  P  RS     RP  P P      R+     AL  P +   P    P  
Sbjct: 621  KPGTPIVLRRAQPRARSSNDARRPPAPQPAP----RTLSHWSALLSPPVPPRPPSSGPPP 676

Query: 76   AVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPA 135
            A P +      PR  +   S  R PP    APA  P  P    +A   A  E        
Sbjct: 677  APPLSPALSGLPRPASPYGSLRRHPPPWA-APAHVPPAP----QASWWAFVEPPAVSPEV 731

Query: 136  YPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDA 195
             P L A        +   +RG           A R     P A P P +R    +     
Sbjct: 732  PPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSP 791

Query: 196  VLQHATRGSRSCGPTE----------AAHWARPAPQFHG--LTVPGPRHMALSRTPTPSD 243
            +   + + S   GP +           +    PAP+     L  PG       R P+P  
Sbjct: 792  LAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPL 851

Query: 244  SYCADPRAFYCDGPL-----------PGPRDYAERRSLPFTTPP------GPTQFFYT-E 285
              C  PR    + P            P  R    +  LPF  PP       P +   +  
Sbjct: 852  GLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPLEHRESPR 911

Query: 286  EPQGFRGSFAASP-GPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSY 344
            EP+     +   P  P++D   P   P++    P P   G    G  R  P+ E P    
Sbjct: 912  EPEDSETPWTVPPLAPSWDVDMP---PTQRPPSPWPGGAGS-RRGFSRPPPVPENPFLQL 967

Query: 345  YGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRE---RDVLARTYPHPRSSPAW 401
             G  P        P   PE+P A  T R F     GR+ E     +     P P      
Sbjct: 968  LGPVP-------SPTLQPEDPAADMT-RVF----LGRHHEPGPGQLTKSAGPTPEKPEEE 1015

Query: 402  ADWG----------PRPYRTLQVVPPSDPDP 422
            A  G          P P     V PP D  P
Sbjct: 1016 ATLGDPQLPAETKPPTPAPPKDVTPPKDITP 1046



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 125/520 (24%), Positives = 172/520 (33%), Gaps = 83/520 (15%)

Query: 174  PEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPT-EAAHWARPAPQFHGLTVPGPRH 232
            P P    A  ++  L  K   A L+ + + +R+ GP    A + R   +  G+    P  
Sbjct: 566  PRPATSLARFLKKTLSEKKPIARLRGSQK-ARAGGPAVREAAYKRFGYKLAGMDPEKPGT 624

Query: 233  MALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRG 292
              + R   P      D R      P P PR  +   +L   +PP P              
Sbjct: 625  PIVLRRAQPRARSSNDARR--PPAPQPAPRTLSHWSAL--LSPPVP-------------- 666

Query: 293  SFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPP--SRSYYGEAPR 350
                 P P      P P  S  LSG  PR    Y  G +R  P   PP  + ++   AP+
Sbjct: 667  -----PRPPSSGPPPAPPLSPALSG-LPRPASPY--GSLRRHP---PPWAAPAHVPPAPQ 715

Query: 351  A--YGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRP 408
            A  +     P   PE P     A P     F   R R      +  P +SP       R 
Sbjct: 716  ASWWAFVEPPAVSPEVP-PDLLAFPGPRPSFRGSRRRGA---AFGFPGASP-------RA 764

Query: 409  YRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRS---WDNILAPGPRREDPLGR 465
             R     P + P P L S  G    SP  LA  S   S     +     P  RR   L  
Sbjct: 765  SRRRAWSPLASPQPSLRSSPGLGYCSP--LAPPSPQLSLRTGPFQPPFLPPARRPRSLQE 822

Query: 466  GRSYENLLGREVREPRGVSPEGRRPPVV-VNLSTSPRRYAALSLSETSLTEKGRAGEGLG 524
              +     GR +  P    P   RPP   + L  SPRR ++L+L         R  E   
Sbjct: 823  SPAPRRAAGR-LGPPGSPLPGSPRPPSPPLGLCHSPRR-SSLNLPSRLPHTWRRLSEPPT 880

Query: 525  RNWYVTPEITIT------------------------DNDLRATERPSARAWELPGGRTRP 560
            R   V P++ +                         D++   T  P A +W++    T+ 
Sbjct: 881  RA--VKPQVRLPFHRPPRAGAWRAPLEHRESPREPEDSETPWTVPPLAPSWDVDMPPTQR 938

Query: 561  PPHAAPDGPTS--GRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRP 618
            PP   P G  S  G  R     +     L+        Q  +PAAD     L R  +  P
Sbjct: 939  PPSPWPGGAGSRRGFSRPPPVPENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGP 998

Query: 619  AGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSAD 658
             G    +  P    P    +  +P  P E    +P P  D
Sbjct: 999  -GQLTKSAGPTPEKPEEEATLGDPQLPAETKPPTPAPPKD 1037



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 58/192 (30%), Positives = 72/192 (37%), Gaps = 37/192 (19%)

Query: 482 GVSPEGRRPPVVVNLSTSPRRYAALSLSETSL------TEKGRAGEGLGRNWY------- 528
           G  PE  RP  V   +TS  R+   +LSE         ++K RAG    R          
Sbjct: 556 GFGPEFGRP--VPRPATSLARFLKKTLSEKKPIARLRGSQKARAGGPAVREAAYKRFGYK 613

Query: 529 ---VTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELIT 585
              + PE   T   LR   R   RA      R  P P  AP        R+L     L++
Sbjct: 614 LAGMDPEKPGTPIVLR---RAQPRARSSNDARRPPAPQPAP--------RTLSHWSALLS 662

Query: 586 DLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAP 645
             V    P++G    P A  L P L  L   RPA   +P  +  R PP  A  A  P AP
Sbjct: 663 PPVPPRPPSSGP---PPAPPLSPALSGL--PRPA---SPYGSLRRHPPPWAAPAHVPPAP 714

Query: 646 GEAADASPEPSA 657
             +  A  EP A
Sbjct: 715 QASWWAFVEPPA 726


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 53/158 (33%), Positives = 59/158 (37%), Gaps = 34/158 (21%)

Query: 26  ASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPP-PESAVPRARTRE 84
           A++  P  R    PA P     R  R      A   P     P PPP P +A   AR   
Sbjct: 96  AARVQPPRRGATPPAPP-----RAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARA-- 148

Query: 85  AEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALAN 144
             PR  A   +A  APP  +P PA P      G  AQRAA   A P    A PA+   A 
Sbjct: 149 --PRAAA---AAATAPP--SPGPAQP------GPRAQRAAPLAAPPPAPAAPPAVAPPA- 194

Query: 145 ELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAP 182
                       GP R  P   AA     P PP  PAP
Sbjct: 195 ------------GPRRAPPPAVAAREPPLPPPPQPPAP 220



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 40/135 (29%), Positives = 46/135 (34%), Gaps = 21/135 (15%)

Query: 150 KLQPQRGGPGRVAP------LCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRG 203
           ++QP R G    AP        AAA   APP  PA P P         P         R 
Sbjct: 98  RVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPP---------PAPVAAAAPARA 148

Query: 204 SRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRD 263
            R+     AA  A P+P   G   PGPR    +    P  +  A P      GP   P  
Sbjct: 149 PRAAA---AAATAPPSP---GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPP 202

Query: 264 YAERRSLPFTTPPGP 278
               R  P   PP P
Sbjct: 203 AVAAREPPLPPPPQP 217



 Score = 33.9 bits (76), Expect = 0.76
 Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 7/97 (7%)

Query: 790 APLGSYARELAAAGR---LYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSHGPTVRK 846
           AP G+ A   AAA        P    + + + A  P  A     A P+P P   GP  ++
Sbjct: 114 APRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQR 173

Query: 847 FAKVALAAGSPARP----PPARSREPDMETLILTPPP 879
            A +A    +PA P    PPA  R      +    PP
Sbjct: 174 AAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPP 210



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 29/88 (32%), Positives = 37/88 (42%), Gaps = 12/88 (13%)

Query: 822 PGTAPPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGT 881
           P  AP   PA+  PA    GP  R+    A+AA  P  PPP +   P  +     PPP  
Sbjct: 180 PPPAPAAPPAVAPPA----GP--RRAPPPAVAAREPPLPPPPQPPAPPQQQ---QPPPPQ 230

Query: 882 AGLDQDG---EAGRRAREVAFIHIQREL 906
                +G    AG  AR V+   + R L
Sbjct: 231 PQPPPEGGAVRAGGAARPVSLREVVRYL 258



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 16/102 (15%)

Query: 568 GPTSGRQRSLEQLDELITDLVI--------DSRPTAGQASEPAADCLGPQLRRLLDSRPA 619
           GP   R R+  +L++LI    +         S   A +   P      P   R     PA
Sbjct: 63  GPEPERTRA--ELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPA 120

Query: 620 GSGA------PALAPPRSPPASAGSAEEPAAPGEAADASPEP 655
            + A      PA  PP +P A+A  A  P A   AA A P P
Sbjct: 121 AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 38/136 (27%), Positives = 46/136 (33%), Gaps = 26/136 (19%)

Query: 20  VATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMET---LPEPPPPESA 76
           VA   PA        +   P  P P             A  GP  +    L  PPP  +A
Sbjct: 140 VAAAAPARAPRAAAAAATAPPSPGP-------------AQPGPRAQRAAPLAAPPPAPAA 186

Query: 77  VPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAY 136
            P A    A PRR      A R PP   P P  PP  P      Q+       P+  P  
Sbjct: 187 -PPAVAPPAGPRRAPPPAVAAREPP--LPPPPQPPAPP------QQQQPPPPQPQPPPEG 237

Query: 137 PALRALANELHPIKLQ 152
            A+RA      P+ L+
Sbjct: 238 GAVRA-GGAARPVSLR 252



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 27/102 (26%), Positives = 39/102 (38%), Gaps = 13/102 (12%)

Query: 560 PPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRR---LLDS 616
           PPP  AP  P +    +              + P+ G A        GP+ +R   L   
Sbjct: 127 PPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP------GPRAQRAAPLAAP 180

Query: 617 RPAGSGAPALAP----PRSPPASAGSAEEPAAPGEAADASPE 654
            PA +  PA+AP     R+PP +  + E P  P     A P+
Sbjct: 181 PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQ 222


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 81/331 (24%), Positives = 103/331 (31%), Gaps = 33/331 (9%)

Query: 20  VATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPR 79
           ++ PGP     P       P  P P   +            GP     P  PP ++    
Sbjct: 175 ISVPGPMGPSGP-RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDG 233

Query: 80  ARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASP---RREPAY 136
              +   P  R      P+   GL      P +   RG      A+ +A P   + EP  
Sbjct: 234 EAGKPGRPGERG--PPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291

Query: 137 PALRALANELHPIKLQPQRGGPGRVAPLCA-----AAGRCAPPEP--PAGPAPH---VRC 186
           P       ++ P  L  +RG PG   P  A     A G   PP P  PAGP      V  
Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA 351

Query: 187 RLDIKPDDAVLQHATRGSR-SCGPTEAAHWARPAPQFHGLTVPGPR--HMALSRTPTPSD 243
           + +  P         +G R   GP   A  A PA        PG +  + A      P  
Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411

Query: 244 SYCADPRAFYCDGPLPGPRDYAERRSLPFTT-------PPGPTQFFYTEEPQGFRGSFAA 296
                P      G  PGP+  +     P +         PGP        P G  G   A
Sbjct: 412 PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471

Query: 297 --SPGPTFDAYYPRPYPSEELSGPSPRRMGG 325
              PGPT       P P  E  GP  R   G
Sbjct: 472 RGEPGPT-----GLPGPPGERGGPGSRGFPG 497



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 74/281 (26%), Positives = 86/281 (30%), Gaps = 36/281 (12%)

Query: 92   RSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKL 151
            R  + P  PPG   AP         G      AR     R EP  P     A        
Sbjct: 763  RGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ 822

Query: 152  QPQRGGPGRVAPLCAAAGRCAPPEP--PAGPAPHVRCRLDIKPDDAVLQHATRGSR-SCG 208
               +G PG       A G   PP P  PAGP           P   V     +G+R S G
Sbjct: 823  PGAKGEPGD----AGAKGDAGPPGPAGPAGPP---------GPIGNVGAPGAKGARGSAG 869

Query: 209  PTEAAHW-------ARPAPQFHG--LTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLP 259
            P  A  +         P P  +      PGP      + P         P      GP P
Sbjct: 870  PPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV---GP-P 925

Query: 260  GPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRG--SFAASPGPTFDAYYP-RPYPSEELS 316
            GP   A  +  P     GP     T  PQG  G       PG   +  +P  P PS E  
Sbjct: 926  GPPGPAGEKGSP--GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG 983

Query: 317  GPSPRRMGGYYA--GEVRTFPIQEPPSRSYYGEAPRAYGLP 355
               P    G     G +    +  PP  S    AP A G P
Sbjct: 984  KQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP 1024



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 95/391 (24%), Positives = 121/391 (30%), Gaps = 96/391 (24%)

Query: 24   GPASKCSPCER--SVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPP-------- 73
            GP  +  P  R   V  P  P P  ++           DGPA    P  P P        
Sbjct: 908  GPRGETGPAGRPGEVGPPGPPGPAGEKGS------PGADGPA--GAPGTPGPQGIAGQRG 959

Query: 74   ---------ESAVPRARTREAEPRRRARS-KSAPRAPPGL--TPAPASPPVLPRRGREAQ 121
                     E   P       EP ++  S  S  R PPG    P  A PP     GRE  
Sbjct: 960  VVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP--GESGREG- 1016

Query: 122  RAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAP-----PEP 176
             A  AE SP R+ + P  +    E  P       G PG   P+   AG+        P  
Sbjct: 1017 -APGAEGSPGRDGS-PGAKGDRGETGPAGPPGAPGAPGAPGPV-GPAGKSGDRGETGPAG 1073

Query: 177  PAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALS 236
            PAGP   V  R    P         RG +     +     +    F GL  P        
Sbjct: 1074 PAGPVGPVGARGPAGP------QGPRGDKGETGEQGDRGIKGHRGFSGLQGP-------- 1119

Query: 237  RTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAA 296
              P P  S              PG +              GP+       P G RG   +
Sbjct: 1120 --PGPPGS--------------PGEQ--------------GPSG---ASGPAGPRGPPGS 1146

Query: 297  SPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPY 356
            +  P  D     P P   +  P PR   G  AG V       PP        P + G  +
Sbjct: 1147 AGAPGKDGLNGLPGP---IGPPGPRGRTG-DAGPVGPPGPPGPPG----PPGPPSAGFDF 1198

Query: 357  GPRYVPEEPRAHSTARPFYTEDFGRYRERDV 387
                 P + +AH   R +  +D    R+RD+
Sbjct: 1199 SFLPQPPQEKAHDGGRYYRADDANVVRDRDL 1229



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 26/72 (36%), Positives = 31/72 (43%), Gaps = 13/72 (18%)

Query: 595 AGQASEPAADCLGPQLRRLLDSRPAGSGAP----ALAP-----PRSPPASAGSAEEPAAP 645
           AG A  P AD  G    +  +  P  +GAP    A  P     P  PP   G++ EP AP
Sbjct: 382 AGPAGNPGAD--GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAP 439

Query: 646 GEAAD--ASPEP 655
           G   D  A  EP
Sbjct: 440 GSKGDTGAKGEP 451


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 84/329 (25%), Positives = 112/329 (34%), Gaps = 39/329 (11%)

Query: 22  TPGPASKCSPCERSVA---------RPAEPA----PFNKRHCRSFDFLEALDGPAMETLP 68
           TP PA+   P ++  A         +P+ P+    P    H        +    A+ T  
Sbjct: 347 TPRPAA-AQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQK 405

Query: 69  EPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLT-PAP----ASPPVLPRRGR----- 118
           + PP    VP   +R AE +   R+   PR PP  T P P    +S   +P   R     
Sbjct: 406 QVPPTSRPVPARVSRPAE-KPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKI 464

Query: 119 --EAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLC-AAAGRCAPPE 175
              A + A A  S  + P + AL + +    P   +  R     V P    +  R AP  
Sbjct: 465 TSHASKPASARTSTHKPPPFTALSS-SPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAV 523

Query: 176 PPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMAL 235
           P  G AP    +  I  + +         R   P      AR  P     T P PR    
Sbjct: 524 PTPGSAP-TGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQP 582

Query: 236 SRTPTPSDSYCADPRAFYCDGPLPGPRDYA---ERRSLPFTT---PPGPTQFFYTEEPQG 289
           S+  TP  +    P  F    P P    Y+      S PF     PPGP        P G
Sbjct: 583 SQQTTP--ALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPG 640

Query: 290 FRGSFAASPGPTFDAYYPRPYPSEELSGP 318
             G     PG       P PY +  L GP
Sbjct: 641 LPG-LPGIPGARGPRGPPGPYGNPGLPGP 668


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 83/332 (25%), Positives = 113/332 (34%), Gaps = 67/332 (20%)

Query: 62   PAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRA--PPGLTPAPASPP--VLPRRG 117
            P+    P+ PPP +A P     +  P   A    +P A  PP + P  A+PP  V P   
Sbjct: 718  PSATPPPQAPPPLAAPPL----QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773

Query: 118  REAQRAARAEASPRREPAY--PALRALANE------------LHPIKLQPQRGGPGRVAP 163
                 +  A+  P+  PA   P L+AL +                + + P    P +  P
Sbjct: 774  ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833

Query: 164  LCAAAGRCAPPEPPAGP---APH-------------VRCRLDIKPDDAVLQHATRGSRSC 207
            + AA     PP PPA P   AP               R  L + P        +  S   
Sbjct: 834  VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893

Query: 208  GPTEAAHW--ARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYA 265
            GP  A H   A   P+       GP   A +  P  ++     P A +  GP P P  + 
Sbjct: 894  GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA-WSRGPAP-PLAFR 951

Query: 266  ERRSLPFTTPP--------GPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSG 317
                 P   PP        G    + TE P+      +A+P P   A  P         G
Sbjct: 952  GAPGAPLPWPPATGPGSADGLCTIYETEGPE------SATPAP--GALDP---------G 994

Query: 318  PSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAP 349
            PSP   GG  A           P ++  GE P
Sbjct: 995  PSPGTSGGKAAAGAGAGASSRSPKQARLGELP 1026



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 77/318 (24%), Positives = 100/318 (31%), Gaps = 38/318 (11%)

Query: 21  ATPGPASKCSP-CERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPR 79
           A P P +   P    S+A P   AP             AL  P ++ LP PP    A P 
Sbjct: 571 APPSPLTTPPPETPSSIATPPPQAP------------PALASPPLQGLPSPPLSPLATPP 618

Query: 80  ARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPAL 139
               +A P        AP +PP     P SP   P        A     +P   P  P +
Sbjct: 619 P---QAPPXLALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673

Query: 140 RALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP--APHVRCRLDIKPDDAVL 197
           +A  +      + P    P +  P  AA     PP PPA P  +P         P  A  
Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733

Query: 198 QHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHM-----------ALSRTPTPSDSYC 246
                 S    P  +   A P P+   L    P  +            L++ P  +    
Sbjct: 734 PLQVPPSPPASPPMSPS-ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792

Query: 247 ADPRAFYCDGP---LPGPRDYAERRSLPFT---TPPGPTQFFYTEEPQGFRGSFAASPGP 300
           A P       P    PG   ++   SLP +   TPP                S  ASP  
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852

Query: 301 TFDAYYPRPYPSEELSGP 318
                 P P P   +SGP
Sbjct: 853 QAPRRPPTPGPDTSVSGP 870



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 66/262 (25%), Positives = 90/262 (34%), Gaps = 37/262 (14%)

Query: 406 PRPYRTLQVVPPSDPDPL-LASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLG 464
           PRP  + +  PP  P  L +    G  G  P       R        I    PR      
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKP----LAERAGGIGGATIPESAPRAGPTRS 82

Query: 465 RGRSYENLLGREVREPRGVSPEGRRPPVVVNLS----TSPRRYAA-----------LSLS 509
            G S  N   R     RG      R P   N S    +SP R +            L +S
Sbjct: 83  AGTSSRNPASRPPASGRG-----ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137

Query: 510 ETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPS----ARAWELPGGRTRPPPHAA 565
                 +G+A E   R+         T      T  P+    +RA     G  RP P A 
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197

Query: 566 PDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPA 625
           P  PT G ++S+    E  T     + P+      P+A   G  L+R      + S  P 
Sbjct: 198 PRPPTEGPRKSVSSASEHST-----TEPSPAARRRPSA---GGGLQRPASRSLSSSATPL 249

Query: 626 LAPPRSPPASAGSAEEPAAPGE 647
            +P RS P++ G+   PA P +
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQ 271



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 152/671 (22%), Positives = 216/671 (32%), Gaps = 140/671 (20%)

Query: 19  KVATPGPASKCSPCERSVARPAEPAPFNKRHCR-----SFDFLEALDGPAMETLPEPPPP 73
           K  +PGP S  SP   S      P P  ++  R     +    +A + P    L      
Sbjct: 107 KNTSPGPVS--SPGRASGT--TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162

Query: 74  ESAVPRARTREAEPRRRARSKSA----PRAPPGLTPAPASPPVLPRRG-REAQRAARAEA 128
           +++ P   T      RR+R+       PR  P   P P  P   PR+    A   +  E 
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEP 220

Query: 129 SP--RREPAY------PALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGP 180
           SP  RR P+       PA R+L++   P+   P R GP       +A G    P  P+ P
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLS-SPARSGP-------SARGTPRAPAHPSQP 272

Query: 181 APHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPT 240
            P                   +G ++  P +        P+       GP   +   TP+
Sbjct: 273 KP-------------------KGLQALRPPQVT-----PPRKDAAPALGPLSSSPLATPS 308

Query: 241 PSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGP 300
           PS +            P+P P + A    LP T PP P                 A+P P
Sbjct: 309 PSGTKAR---------PVPPPDNAA--TPLPATLPPSPP---------------LATPLP 342

Query: 301 TFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRY 360
                   P   + L  P P          + T P+Q PPS          + L      
Sbjct: 343 LAPPSPSAPPSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401

Query: 361 VPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPP-SD 419
            P  P A S+ +   T   G    +   +     PR + A      RP  T    PP   
Sbjct: 402 APPSPLALSSLQA--TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459

Query: 420 PDPLLASWHGGTGTSP---PRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGRE 476
           P  L AS    T  SP   P  +  + H  ++  ++ +  P  + PL       +L+   
Sbjct: 460 PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP--QAPL------SSLIMPP 511

Query: 477 VREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITIT 536
           +     ++P   + P   +L+T P      +L   +      A   L      TP     
Sbjct: 512 LETQSSLAPPSLQTP-PASLTTPPLE----NLPSLAPPPLQTASAPLTTPHLETPPCP-A 565

Query: 537 DNDLRATERP-SARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTA 595
              L+A   P +    E P     PPP A P                      + S P  
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPP---------------------ALASPPLQ 604

Query: 596 GQASEPAADCLGPQLRRLLDSRPAGSGAPAL----APPRSPPASAGSAEEPAAPGE---- 647
           G  S P +    P         P     P L    +PP SPP S  +   P AP      
Sbjct: 605 GLPSPPLSPLATPP-----PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659

Query: 648 --AADASPEPS 656
              A  SP PS
Sbjct: 660 LLQAPFSPPPS 670



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 139/630 (22%), Positives = 184/630 (29%), Gaps = 126/630 (20%)

Query: 62  PAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQ 121
           P   TLP  PP  + +P A               +P APP L   P+ P   P +   + 
Sbjct: 326 PLPATLPPSPPLATPLPLA-------------PPSPSAPPSLQTLPSPPATPPSQAPPSM 372

Query: 122 RAARAEASPRREP----------AYPALRALANELHPIKLQ--PQRGGPG--------RV 161
                +A P  +             P+L+A  + L    LQ     G P          +
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432

Query: 162 APLCAAAGRCAPPEPPAGP--APHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPA 219
           +P    A   +P  P + P  +P ++  L + P    LQ  T  S +  P  +     P 
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSL-PASPPLQ--TSLSPAVSPLSSPLTIHPL 489

Query: 220 PQFHGLTVPGPRH--MALSRTPTPSDSYCADPR-----AFYCDGPLPGPRDYA----ERR 268
                L    P+    +L   P  + S  A P      A     PL      A    +  
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549

Query: 269 SLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYA 328
           S P TTP   T       P     S   +P P   +    P P    +  SP   G    
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG---L 606

Query: 329 GEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDV- 387
                 P+  PP      +AP    LP  P   P  P A     P  T          V 
Sbjct: 607 PSPPLSPLATPPP-----QAPPXLALP--PLQAPPSPPASPPLSPLATPSPQAPNALAVH 659

Query: 388 -LARTYPHPRSSPAWADWGP--RPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRH 444
            L   +  P S P  A + P   P  +    PPS   P LA        +PP     S  
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA--------APPLQVPPSPP 711

Query: 445 YSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYA 504
            S        P P+   PL                P  V P     P +   +T P R  
Sbjct: 712 ASPPMSPSATPPPQAPPPL-------------AAPPLQVPPSPPASPPMSPSATPPPRVP 758

Query: 505 ALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHA 564
            L                L       P        +    +P  +A   P     PP  A
Sbjct: 759 PL----------------LAAPPLQVPPSPPASLPMSPLAKPPPQA---PPALATPPLQA 799

Query: 565 APDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAP 624
            P  P S   ++                P +  AS P +    P         P    AP
Sbjct: 800 LPSPPASFPGQA----------------PFSPSASLPMSPLATPP-----PQAPPVLAAP 838

Query: 625 ALAPPRSPPAS--AGSAEEPAAPGEAADAS 652
            L  P SPPAS    +   P  PG     S
Sbjct: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 87/373 (23%), Positives = 114/373 (30%), Gaps = 51/373 (13%)

Query: 92  RSKSAPRAPPGLTPA---------PASPPVLPRRGREAQRAARAEASPRREPAYPALRAL 142
           R   +PR PP +TPA               L  R      A   E++PR   A P   A 
Sbjct: 28  RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR---AGPTRSAG 84

Query: 143 ANELHPIKLQPQRGGPGRVAPL-CAAAGRCAPPEPPAG---PAPHVRCRLDIKPDDAVLQ 198
            +  +P    P  G   R  P    + G  + P   +G   P P  +  L I  ++ V  
Sbjct: 85  TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV-- 142

Query: 199 HATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPL 258
              RG  +  P  +A  A       G T PG    A++R    + +    PR      P 
Sbjct: 143 --ARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199

Query: 259 P---GPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEEL 315
           P   GPR      S   TT P P        P    G     P     +    P  S   
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAA---RRRPSA--GGGLQRPASRSLSSSATPLSSPAR 254

Query: 316 SGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLP--YGPRYVPEEPRAHSTARP 373
           SGPS R                  P    +   P+  GL     P+  P    A     P
Sbjct: 255 SGPSAR----------------GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298

Query: 374 FYTEDFGRYRERDVLARTYPHPRSS----PAWADWGPRPYRTLQVVPPSDPDPLLASWHG 429
             +            AR  P P ++    PA     P     L + PPS   P       
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358

Query: 430 GTGTSPPRLATDS 442
               +PP  A  S
Sbjct: 359 SPPATPPSQAPPS 371



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 146/603 (24%), Positives = 184/603 (30%), Gaps = 102/603 (16%)

Query: 96  APRAPPGLTPAPAS-----PPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIK 150
           A RAP  LTP P       PPV P   R    A      P  E A     A   E  P  
Sbjct: 18  AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP-- 75

Query: 151 LQPQRGGPGRVA----------PLCAAAGRCAPPEPPAGPAP---HVRCRLDIKPDDAVL 197
               R GP R A          P  +  G  APP     P P     R     +P     
Sbjct: 76  ----RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL-- 129

Query: 198 QHATRGSR-SCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDG 256
               +G R S   T A   A  AP+   L+    R  +     TPS +     RA   + 
Sbjct: 130 --GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187

Query: 257 PLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELS 316
            LP P   A  R      PP       TE P+  +   +AS   T +     P P+   +
Sbjct: 188 GLPRPAPSARPR------PP-------TEGPR--KSVSSASEHSTTE-----PSPA---A 224

Query: 317 GPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPE-EPRAHSTARPFY 375
              P   GG      R+      P  S     P A G P  P +  + +P+     RP  
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284

Query: 376 TEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSP 435
                R      L      P ++P+ +    RP      VPP  PD            SP
Sbjct: 285 VTP-PRKDAAPALGPLSSSPLATPSPSGTKARP------VPP--PDNAATPLPATLPPSP 335

Query: 436 PRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVV- 494
           P LAT            LAP      P     S + L       P    P    PP+   
Sbjct: 336 P-LATPLP---------LAPPSPSAPP-----SLQTLPSPPATPPSQAPPSMTTPPMQAP 380

Query: 495 -NLSTSPRRYAALSLSETSL--------TEKGRAGEGLGRNWYVTPEITITDNDLRATER 545
            +L T P      SL+  SL            +A   LG     +P +  T + L  + R
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG-----SPTLQATHSFLTMSPR 435

Query: 546 PSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADC 605
            +  +   P      P    PD P      SL     L T L     P     S P    
Sbjct: 436 QTQASLTSPS----RPASTPPDSPPLQAPLSLPASPPLQTSL----SPAVSPLSSPLTIH 487

Query: 606 LGPQLRRLLDSRPAGSGAPALAPPRSPPASAG--SAEEPAAPGEAADASPEPSADEDDLM 663
               L  L    P    +  + PP    +S    S + P A          PS     L 
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547

Query: 664 TCS 666
           T S
Sbjct: 548 TAS 550


>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
          Length = 1159

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 40/116 (34%), Positives = 51/116 (43%), Gaps = 14/116 (12%)

Query: 545 RPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAAD 604
           R  +RA + PG   R P   AP  P S R R L     L+  L++ +   AG++ EP   
Sbjct: 4   RGPSRASKGPGPTARAPSPGAPPPPRSPRSRPL-----LLLLLLLGACGAAGRSPEPGR- 57

Query: 605 CLGP--QLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSAD 658
            LGP  QL R+  S PAG   P     R          EP APG +   +P P  D
Sbjct: 58  -LGPHAQLTRVPRSPPAGRAEPGGGEDRQ-----ARGTEPGAPGPSPGPAPGPGED 107


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 88/353 (24%), Positives = 126/353 (35%), Gaps = 60/353 (16%)

Query: 11   VSTVYQDIKVATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEP 70
            ++T+ Q  + ATP      +P   S        P  ++         AL GP    +P+ 
Sbjct: 1852 LATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKT 1911

Query: 71   PPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAAR----- 125
            P       + +T+ +  R     + A R PP L  A   P    R G EA   AR     
Sbjct: 1912 PARTLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGRLG 1971

Query: 126  -----------AEASP----RREPAY----PALRALANELH--------PIKLQPQRGGP 158
                       +E+S     RR+  +    P LR   +EL         P    P+RG P
Sbjct: 1972 LVRVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESAASAPQGASPRRGRP 2031

Query: 159  GRVAP-LCAAAGRCAPPEPPAGPAPHVRCRLDI---KPDDAVLQHATRGSRSCGPTEAAH 214
               A  LC++        P  GPAP  R R       P +   +  T  S S  P  A  
Sbjct: 2032 ALPAVFLCSSRCEELRAAPRQGPAP-ARQRPPAARPSPGERPARRTTSESPSRLPVRAPA 2090

Query: 215  WARPAPQFHGLTVPGPRHMALSRTP---TPSDSYCADPRAFYCDGPLPGPRDYAERRSLP 271
             ARP       ++P   H++++R P    P+    AD      DG         E R LP
Sbjct: 2091 -ARPETVKRYASLP---HISVARRPDGAVPAAPASADAARRSSDG---------EPRPLP 2137

Query: 272  FTTPPGPTQFFYTEE--PQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRR 322
                PG T     +E  P   R +  A+  P   +      P +  +GP PR+
Sbjct: 2138 RVAAPGTTWRRIRDEDVPHILRSTLPATALPLRGS-----TPEDAPAGPPPRK 2185



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 42/145 (28%), Positives = 51/145 (35%), Gaps = 26/145 (17%)

Query: 531  PEITITDNDLRATERPSARAWELPGGRTRPPP--HAAPDGPTSGRQRSLEQLDELITDLV 588
            P    T    R +  P A   E P GR   P    AAP  P   R +           L+
Sbjct: 1519 PAAAPTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQP---------SLI 1569

Query: 589  IDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEA 648
             D  P     S  A+            S P  S  PA+ P    PA      +   PG  
Sbjct: 1570 ADETPPCYSLSSSASSL----------SEPEPSEPPAVHPRGREPA----VTKDPGPGGG 1615

Query: 649  ADASPEPSADEDDLMTC-SNARCRR 672
             D+SP P A E+ L  C S+A  RR
Sbjct: 1616 RDSSPSPRAAEELLQRCISSALPRR 1640



 Score = 37.0 bits (84), Expect = 0.090
 Identities = 38/123 (30%), Positives = 51/123 (41%), Gaps = 32/123 (26%)

Query: 75   SAVPRARTREAEPRRR---ARSKSAPRAPPGLTPAPASPPVL-----PRRGREAQRAARA 126
            SA+PRA TRE    R+   A SK+AP APP   PA   P ++     P     +  ++ +
Sbjct: 1531 SAIPRAFTRERPQGRKEAPAPSKAAPAAPP---PARTQPSLIADETPPCYSLSSSASSLS 1587

Query: 127  EASPRREPAYPALRALANELHPIKLQP---QRGGPGRVAPLCAAAGRCAPPEPPAGPAPH 183
            E  P   PA          +HP   +P   +  GPG         GR + P P A     
Sbjct: 1588 EPEPSEPPA----------VHPRGREPAVTKDPGPG--------GGRDSSPSPRAAEELL 1629

Query: 184  VRC 186
             RC
Sbjct: 1630 QRC 1632



 Score = 34.3 bits (77), Expect = 0.58
 Identities = 53/189 (28%), Positives = 65/189 (34%), Gaps = 39/189 (20%)

Query: 72   PPESAVPRART--REAEPRRRARSKSAPRAPPGLTPAPASPPVL-------------PRR 116
            P   AV R RT      P  RA+ K  P   P  TP   +PP L              +R
Sbjct: 1782 PGVPAVLRGRTVIYVPSPAPRAQPKGTPG--PRATPRKVAPPCLAQPAAPAKVPSPGQQR 1839

Query: 117  GREAQRAARAE-----ASPRREPAYPALRALANELHPIKLQP-QRGGPGRVAPLCAAAGR 170
             R   R A+       + P R    PA  A        +  P  +  P +  P+  AAG 
Sbjct: 1840 SRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAG- 1898

Query: 171  CAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPA-----PQFHGL 225
             A P P A P P    R  +       QH T+ S    P       RPA     P    +
Sbjct: 1899 -ALPGPGASPVPKTPARTLL-----AKQHKTQRS----PVRIPFMQRPARRGPPPLARAV 1948

Query: 226  TVPGPRHMA 234
              PGPR  A
Sbjct: 1949 PEPGPRGRA 1957


>gi|239757987 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 445

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 71/260 (27%), Positives = 87/260 (33%), Gaps = 48/260 (18%)

Query: 58  ALDGPAMETLPEPPPPES---------AVPRARTREAEPRRRARSKSAPRAPPGLTPAPA 108
           A  G  +   P+ PP  S         A  RA T E +       ++ P  P  L PAP 
Sbjct: 176 AAPGRRLRGEPKTPPGRSGPSGGVRSGAGHRAATAEHQLGAGFSVRNGPGPPARLPPAPP 235

Query: 109 SPPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAA 168
            PP+ P         AR      R P     R L  E    KL P         PLC + 
Sbjct: 236 GPPLRP---------ARPHNPTSRGPG----RLLTCEPPSRKLPPP-------LPLCRSR 275

Query: 169 GRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVP 228
              APP     P    R R+   P   +     RGSR+     A    R A     LT+ 
Sbjct: 276 WVLAPP-----PTVRPRLRVLTPPFTLLCALPERGSRTPSTRSAVLVDRVAGLGTELTLT 330

Query: 229 GPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQ 288
                A    P  S+   A  RAF    PLP P  +    SLP     G        +P+
Sbjct: 331 PSSRRAHGSHPLSSERQAAPTRAFCSADPLPRPPSFVP--SLPSPQAQGQA----VRQPR 384

Query: 289 GFRGSFA--------ASPGP 300
             R + A         SPGP
Sbjct: 385 LLRAALALGAPRGRTPSPGP 404



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 30/74 (40%), Positives = 34/74 (45%), Gaps = 21/74 (28%)

Query: 817 SVAVGPGT------APPGTPALPAPAPRSHGPTVRKFAKVALAAGSPAR--PPP---ARS 865
           SV  GPG       APPG P  PA   R H PT R   ++ L    P+R  PPP    RS
Sbjct: 219 SVRNGPGPPARLPPAPPGPPLRPA---RPHNPTSRGPGRL-LTCEPPSRKLPPPLPLCRS 274

Query: 866 REPDMETLILTPPP 879
           R       +L PPP
Sbjct: 275 R------WVLAPPP 282


>gi|239741896 PREDICTED: hypothetical protein XP_002342335 [Homo
           sapiens]
          Length = 347

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 66/240 (27%), Positives = 93/240 (38%), Gaps = 29/240 (12%)

Query: 51  RSFDFLEALDGPAMETLPEP--PPPESAVPRARTREAEPRR-RARSKSAPRAP------- 100
           RSF    A  G A    PEP     +S  P++R  E++P   R +S+ APR+        
Sbjct: 112 RSFTHAGARAGRAS---PEPCRRGAQSMEPQSRAWESQPADGRKQSREAPRSGYEGDGSG 168

Query: 101 PGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGR 160
            G   + A+ P   RR          +  P +E +  + R L     P         P R
Sbjct: 169 RGCRDSGATYPAGARRSLAEAERVGPKPLPEQERSGASGRCL-----PAPAAFSAAAPAR 223

Query: 161 VAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAP 220
             P C   G  AP  PP+   P +   L ++P   +     RG  S G  E       A 
Sbjct: 224 RPPACLPEGEDAPVAPPSSARPALPSFL-LRPSGYLAARRQRGPGS-GAAETGFRGSCAG 281

Query: 221 QFHGLTV---PGPRHMALSRTPTPSD--SYCADPRAFYCDG---PLPGPRDYAE-RRSLP 271
              GL +   PG  H+    + T S+  S  + PR  +  G   P P P  + E RR+LP
Sbjct: 282 CGRGLRIQSHPGTTHLHQGASFTSSEPLSGISSPRGVWASGCLAPFPQPLIHGEQRRALP 341


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 67/250 (26%), Positives = 81/250 (32%), Gaps = 40/250 (16%)

Query: 23  PGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPA-METLPEPPPPESAVPRAR 81
           PGP     P           A  N  H  +       +GPA +  LP+P  P + +    
Sbjct: 184 PGPGKPAGPGAAQTLN-GSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242

Query: 82  TREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRA 141
              A       + S P AP    PA A PP  P           A A+  R P +PA   
Sbjct: 243 FVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP-----------APATLARPPGHPAGPP 291

Query: 142 LANELHPIKLQPQRGGPGRVAPLCAAA--------GRCAPPEPPAGPAPHVRCRLDIKPD 193
            A    P     Q GG    AP  A A        G+  P    A PAP V+     +  
Sbjct: 292 TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV 351

Query: 194 DAVLQHA----------TRGSRSCGPTEAAHWARPA---PQFHGLTVPGPRHMA------ 234
            A    A          T  S   GPT       PA   P   G     P+  A      
Sbjct: 352 QAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQS 411

Query: 235 LSRTPTPSDS 244
           LSRTPT + S
Sbjct: 412 LSRTPTATTS 421



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 83/291 (28%), Positives = 99/291 (34%), Gaps = 54/291 (18%)

Query: 95  SAPRAP----PGLTPAPASPPVLPRRGREAQRAARAEASPRRE--PAYPALRALANELHP 148
           + P AP    PG  P P  PP    R            SPRR   PA PA  A   +L P
Sbjct: 73  AGPAAPAEGAPGAAPEP--PPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA--KLRP 128

Query: 149 IKLQPQRGGPGRVAPLCAAAGRCAPPEP-PAGPAPHVRCRLDIKP-DDAVLQHATRGSRS 206
               P  G  G  AP+ AAA   A PEP PAGPA         KP   A L  A R    
Sbjct: 129 ----PPEGSAGSCAPVPAAAAVAAGPEPAPAGPA---------KPAGPAAL--AARAGPG 173

Query: 207 CGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAE 266
            GP        P P       PGP   A        +   A   + +   P     +   
Sbjct: 174 PGPGPG-----PGPG------PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222

Query: 267 RRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSP------ 320
              LP   P  P     T     F G+ AA P P   +    P P+   + P P      
Sbjct: 223 AALLPLPKPAAPGTVIQTPP---FVGA-AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA 278

Query: 321 --RRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPY----GPRYVPEEP 365
              R  G+ AG     P   PP+ +  G +  A   P     GP  V  +P
Sbjct: 279 TLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP 329



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 91/369 (24%), Positives = 115/369 (31%), Gaps = 38/369 (10%)

Query: 24  GPASKCSPCERSVARPAEPAP--FNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRAR 81
           GP     P  R    PA PAP     R             PA   +   P P  A P   
Sbjct: 101 GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160

Query: 82  TREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEAS--PRREPAYPAL 139
              A    RA     P   PG  P P  P      G  A +     A+       A PA+
Sbjct: 161 AGPAALAARAGPGPGPGPGPGPGPGPGKP-----AGPGAAQTLNGSAALLNSHHAAAPAV 215

Query: 140 RALANELHPIKLQPQRGGPGRV---APLCAAAGRCAP--PEPPAGPAPHVRCRLDIKPDD 194
             + N    +   P+   PG V    P   AA   AP  P PPA PAP         P  
Sbjct: 216 SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP 275

Query: 195 AVLQHATRGSRSCGPTEAAHWARP--APQFHGL--TVPGPRHMA-----LSRTPTPSDSY 245
           A    A       GP  AA    P  A Q  G     P P   A     +S  P P  + 
Sbjct: 276 APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAA 335

Query: 246 CADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAY 305
            A         P PG +  + +R +    P   T       P     S     GPT    
Sbjct: 336 AA---------PAPGVKAESPKRVVQAAPPAAQT--LAASGPASTAASMVI--GPTMQGA 382

Query: 306 YPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEP 365
            P P      +  +P  +    AG V T  +   P+ +  G           PR +P+ P
Sbjct: 383 LPSPAAVPPPAPGTPTGLPKGAAGAV-TQSLSRTPTATTSGIRATLTPTVLAPR-LPQPP 440

Query: 366 RAHSTARPF 374
           +  +  + F
Sbjct: 441 QNPTNIQNF 449



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 142/574 (24%), Positives = 181/574 (31%), Gaps = 122/574 (21%)

Query: 119 EAQRAARAEASPRREPAYPALRALANEL---HPIKLQPQ-RGGPGRVAPLCAAAGRCAPP 174
           E+Q AA A       P  P +RA A      H +   P    G G  AP   A G  AP 
Sbjct: 30  ESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPG-AAPE 88

Query: 175 EPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMA 234
            PPAG A         +P     Q     S    P      A PAP    L  P P   A
Sbjct: 89  PPPAGRA---------RPGGGGPQRPGPPS----PRRPLVPAGPAPPAAKLR-PPPEGSA 134

Query: 235 LSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSF 294
            S  P P+        A    GP P P   A+        P GP              + 
Sbjct: 135 GSCAPVPA-------AAAVAAGPEPAPAGPAK--------PAGPAAL-----------AA 168

Query: 295 AASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGL 354
            A PGP      P P P     GP P +  G   G  +T         S++  AP    +
Sbjct: 169 RAGPGPG-----PGPGPG---PGPGPGKPAG--PGAAQTLNGSAALLNSHHAAAPAVSLV 218

Query: 355 PYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQV 414
             GP  +   P+  +      T  F         A   P   S PA     P P      
Sbjct: 219 NNGPAALLPLPKPAAPGTVIQTPPF-----VGAAAPPAPAAPSPPA----APAPAAPAAA 269

Query: 415 VPPSDPDPLLASWHGGTGTSPPRLA-----TDSRHYSRSWDNILAPGPRREDPLGRGRSY 469
            PP  P P   +   G    PP  A       +     S     AP P    P   G S 
Sbjct: 270 PPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP--AGVSG 327

Query: 470 ENLLGREVREPR-GVSPEGRR------PPVVVNLSTSPRRYAALSL-------------- 508
           +   G     P  GV  E  +      PP    L+ S     A S+              
Sbjct: 328 QPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA 387

Query: 509 --------SETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRP 560
                   + T L  KG AG  + ++   TP  T T + +RAT  P+  A  LP      
Sbjct: 388 AVPPPAPGTPTGL-PKGAAG-AVTQSLSRTP--TATTSGIRATLTPTVLAPRLP------ 437

Query: 561 PPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAG 620
                P  PT+ +   L     L+       R   GQ        L  Q++    ++P  
Sbjct: 438 ---QPPQNPTNIQNFQLPPGMVLV-------RSENGQLLMIPQQALA-QMQAQAHAQPQT 486

Query: 621 SGAPALAPPRS-PPASAGSAEEPAAPGEAADASP 653
           + AP  A P S PP    + + P  P  A   +P
Sbjct: 487 TMAPRPATPTSAPPVQISTVQAPGTPIIARQVTP 520



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 10/76 (13%)

Query: 588 VIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAE---EPAA 644
           VI + P  G A+ PA     P       + PA + APA APP  PPA A  A     PA 
Sbjct: 237 VIQTPPFVGAAAPPAPAAPSPP------AAPAPA-APAAAPPPPPPAPATLARPPGHPAG 289

Query: 645 PGEAADASPEPSADED 660
           P  AA A P P+A ++
Sbjct: 290 PPTAAPAVPPPAAAQN 305



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 39/113 (34%), Positives = 44/113 (38%), Gaps = 26/113 (23%)

Query: 546 PSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADC 605
           P+  A   P       P AAP+ P +GR                 +RP  G    P    
Sbjct: 67  PAGAAGAGPAAPAEGAPGAAPEPPPAGR-----------------ARPGGGGPQRPGP-- 107

Query: 606 LGPQLRRLLDSRPAGSGAPALAPPRSPP-ASAGS-AEEPAAPGEAADASPEPS 656
             P  RR L   PAG   PA A  R PP  SAGS A  PAA   AA   P P+
Sbjct: 108 --PSPRRPLV--PAGPAPPA-AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA 155



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 28/78 (35%), Positives = 29/78 (37%), Gaps = 13/78 (16%)

Query: 816 VSVAVGPGTAPPGTPALPAPAPRSHGPTVRKFAKVALAA--GSPARPPPARSREPDMETL 873
           V  A  P  A P  PA PAPA  +  P     A   LA   G PA PP A          
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP-------- 295

Query: 874 ILTPPPGTAGLDQDGEAG 891
              PPP  A     G AG
Sbjct: 296 -AVPPPAAA--QNGGSAG 310



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 28/74 (37%), Positives = 33/74 (44%), Gaps = 9/74 (12%)

Query: 591 SRPTAGQASEPAADCLGPQLRRLLDSRPAG--SGAPALAPPRSPPA------SAGSAEEP 642
           S P A   + PAA    P       +RP G  +G P  AP   PPA      SAG+A  P
Sbjct: 256 SPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAP 315

Query: 643 A-APGEAADASPEP 655
           A A G  A  S +P
Sbjct: 316 APAAGGPAGVSGQP 329



 Score = 30.4 bits (67), Expect = 8.4
 Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 17/90 (18%)

Query: 821 GPGTAPPGTP------------ALPAPAPRSHGPT-VRKFAKVALAAGSPARPPPARSRE 867
           GP TA P  P            A PAPAP + GP  V        AA +PA  P  ++  
Sbjct: 289 GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA--PGVKAES 346

Query: 868 PDMETLILTPPPGTAGLDQDGEAGRRAREV 897
           P  + ++   PP    L   G A   A  V
Sbjct: 347 P--KRVVQAAPPAAQTLAASGPASTAASMV 374


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 57/228 (25%), Positives = 77/228 (33%), Gaps = 50/228 (21%)

Query: 23  PGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRART 82
           PGP  +  P ++       P P  ++H      L  L  PA   LP+  P  ++ P+   
Sbjct: 472 PGPQRQGPPLQQ------RPPPQGQQH------LSGLGPPAGSPLPQRLPSPTSAPQQPA 519

Query: 83  REAEPRRRARSKSA------PRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAY 136
            +A P  + + + +      P APP   P PASP                  SP+R+   
Sbjct: 520 SQAAPPTQGQGRQSRPVAGGPGAPPAARP-PASP------------------SPQRQAGP 560

Query: 137 PALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAV 196
           P      +   P   +     PG          R  PP+ P GPA   R      P    
Sbjct: 561 PQATRQTSVSGPAPPKASGAPPG-------GQQRQGPPQKPPGPAGPTRQASQAGPVPRT 613

Query: 197 LQHATRGSRSCGPTEAAHWARPAPQF---HGLTVPGPRHMALSRTPTP 241
               T+  R  GP  A    RP PQ        VP P   A    P P
Sbjct: 614 GPPTTQQPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHP 658



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 66/259 (25%), Positives = 100/259 (38%), Gaps = 37/259 (14%)

Query: 84  EAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGRE-AQRAARAEASPRREPAYPALRAL 142
           +A PR+R R  S  R   G TP+P + P+  +  ++ A   A+    P+  P  P     
Sbjct: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG-PGP 474

Query: 143 ANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATR 202
             +  P++ +P   G   ++ L   AG    P P   P+P    +          Q   R
Sbjct: 475 QRQGPPLQQRPPPQGQQHLSGLGPPAG---SPLPQRLPSPTSAPQQPASQAAPPTQGQGR 531

Query: 203 GSRSC-----GPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGP 257
            SR        P  A   A P+PQ         R  ++S  P P  +  A P      GP
Sbjct: 532 QSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVS-GPAPPKASGAPPGGQQRQGP 590

Query: 258 ---LPGP----RDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPY 310
               PGP    R  ++   +P T PP       T++P+       + PGP   A  P+P 
Sbjct: 591 PQKPPGPAGPTRQASQAGPVPRTGPP------TTQQPR------PSGPGP---AGRPKPQ 635

Query: 311 ----PSEELSGPSPRRMGG 325
               PS+++  P+    GG
Sbjct: 636 LAQKPSQDVPPPATAAAGG 654



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 18/120 (15%)

Query: 554 PGGRTRPPPHAAPDGPTSGRQRSLEQLDELI----TDLVIDSRPTAGQ------------ 597
           P  + RPPP   P  P  G QR    L +         +    P AG             
Sbjct: 455 PPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA 514

Query: 598 ASEPAADCLGPQLRRLLDSRP--AGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEP 655
             +PA+    P   +   SRP   G GAP  A P + P+    A  P A  + + + P P
Sbjct: 515 PQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAP 574


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 57/228 (25%), Positives = 77/228 (33%), Gaps = 50/228 (21%)

Query: 23  PGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRART 82
           PGP  +  P ++       P P  ++H      L  L  PA   LP+  P  ++ P+   
Sbjct: 472 PGPQRQGPPLQQ------RPPPQGQQH------LSGLGPPAGSPLPQRLPSPTSAPQQPA 519

Query: 83  REAEPRRRARSKSA------PRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAY 136
            +A P  + + + +      P APP   P PASP                  SP+R+   
Sbjct: 520 SQAAPPTQGQGRQSRPVAGGPGAPPAARP-PASP------------------SPQRQAGP 560

Query: 137 PALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAV 196
           P      +   P   +     PG          R  PP+ P GPA   R      P    
Sbjct: 561 PQATRQTSVSGPAPPKASGAPPG-------GQQRQGPPQKPPGPAGPTRQASQAGPVPRT 613

Query: 197 LQHATRGSRSCGPTEAAHWARPAPQF---HGLTVPGPRHMALSRTPTP 241
               T+  R  GP  A    RP PQ        VP P   A    P P
Sbjct: 614 GPPTTQQPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAGGPPHP 658



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 69/274 (25%), Positives = 106/274 (38%), Gaps = 37/274 (13%)

Query: 84  EAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGRE-AQRAARAEASPRREPAYPALRAL 142
           +A PR+R R  S  R   G TP+P + P+  +  ++ A   A+    P+  P  P     
Sbjct: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG-PGP 474

Query: 143 ANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATR 202
             +  P++ +P   G   ++ L   AG    P P   P+P    +          Q   R
Sbjct: 475 QRQGPPLQQRPPPQGQQHLSGLGPPAG---SPLPQRLPSPTSAPQQPASQAAPPTQGQGR 531

Query: 203 GSRSC-----GPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGP 257
            SR        P  A   A P+PQ         R  ++S  P P  +  A P      GP
Sbjct: 532 QSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVS-GPAPPKASGAPPGGQQRQGP 590

Query: 258 ---LPGP----RDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPY 310
               PGP    R  ++   +P T PP       T++P+       + PGP   A  P+P 
Sbjct: 591 PQKPPGPAGPTRQASQAGPVPRTGPP------TTQQPR------PSGPGP---AGRPKPQ 635

Query: 311 ----PSEELSGPSPRRMGGYYAGEVRTFPIQEPP 340
               PS+++  P+    GG    +++  P Q  P
Sbjct: 636 LAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 18/120 (15%)

Query: 554 PGGRTRPPPHAAPDGPTSGRQRSLEQLDELI----TDLVIDSRPTAGQ------------ 597
           P  + RPPP   P  P  G QR    L +         +    P AG             
Sbjct: 455 PPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA 514

Query: 598 ASEPAADCLGPQLRRLLDSRP--AGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEP 655
             +PA+    P   +   SRP   G GAP  A P + P+    A  P A  + + + P P
Sbjct: 515 PQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAP 574


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 80/277 (28%), Positives = 93/277 (33%), Gaps = 54/277 (19%)

Query: 96  APRAPPGLTPAPASPPVLPRRGR--EAQRAAR---------AEASPRREPAYPALRALAN 144
           +PR P      P  PP  PR G   EA  AAR         A   P   P  P L     
Sbjct: 132 SPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLP 191

Query: 145 ELHPIKLQPQRGGPGRVA----PLCAAAGRCAPPEPPAGPAP--------HVRCRLDIKP 192
              PIK  P    PG +     P+ A    CAPP PP  P P         V     +KP
Sbjct: 192 SSSPIK-TPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKP 250

Query: 193 DDAVLQHATRGS-----RSCG-PTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYC 246
             A L              CG P   A  A PA        P P        P P  + C
Sbjct: 251 QLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP--------PLPPYASC 302

Query: 247 ADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYY 306
           + PRA     PLPG    +E      T PP P +    + P    G+  A P P      
Sbjct: 303 S-PRASLPAPPLPGVNSSSE------TPPPLPPKSPSFQAPPQKAGA-QALPAP------ 348

Query: 307 PRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRS 343
             P P         +R G   AG  +  P   PP+RS
Sbjct: 349 --PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARS 383



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 43/169 (25%), Positives = 58/169 (34%), Gaps = 35/169 (20%)

Query: 26  ASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAV-------P 78
           A++ +P   +V  P  P P                 P    LP P P  S +       P
Sbjct: 161 AARTAPPRPNVPAPPPPTP----------------PPPPPPLPPPLPSSSPIKTPLVSPP 204

Query: 79  RARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPA 138
              T+   P        AP  PP   P P +PP LP     + +A + + +P   P  P 
Sbjct: 205 GPLTKGNLPVVAPPVPCAPPPPP--PPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262

Query: 139 LRALANELHPIKLQPQRGGPG-RVAPLCAAAGRCAPPEPPAGPAPHVRC 186
                    P+ L P  G PG +  P   A     PP PP    P+  C
Sbjct: 263 ---------PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASC 302



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 51/211 (24%), Positives = 71/211 (33%), Gaps = 47/211 (22%)

Query: 6   PPDLLVSTVYQDIKVATPGPASK-----------CSPCERSVARPAEPAPFNKRHCRSFD 54
           PP L  S+  +   V+ PGP +K           C+P       P  P P       S  
Sbjct: 187 PPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDK 246

Query: 55  FLEALDGPAMETLPEPPPP-----ESAVPRARTREAEPRRRARSKSAPRAP--------- 100
            ++    P    LP  PPP         P  +   A P + A+   AP  P         
Sbjct: 247 AVKPQLAPLH--LPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSP 304

Query: 101 ---------PGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKL 151
                    PG+  +  +PP LP +    Q A   +A  +  PA PA         P   
Sbjct: 305 RASLPAPPLPGVNSSSETPPPLPPKSPSFQ-APPQKAGAQALPAPPA----PPGSQPFLQ 359

Query: 152 QPQRGGPGRVAPLCAAAGRCAPPEPPAGPAP 182
           + + G PG      A  G+  PP  P   +P
Sbjct: 360 KKRHGRPG------AGGGKLNPPPAPPARSP 384



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 12/82 (14%)

Query: 802 AGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPP 861
           +G L  PA   L + S A G     P  P +PAP P +  P              P  PP
Sbjct: 141 SGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP------------PPPLPP 188

Query: 862 PARSREPDMETLILTPPPGTAG 883
           P  S  P    L+  P P T G
Sbjct: 189 PLPSSSPIKTPLVSPPGPLTKG 210



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 23/76 (30%), Positives = 28/76 (36%), Gaps = 14/76 (18%)

Query: 826 PPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGTAGLD 885
           PP  P LP P P    P              P  PP A     D  +L    P G + L 
Sbjct: 5   PPPPPPLPPPPPPLGAP--------------PPPPPSAPPVSTDTSSLRRADPKGRSALL 50

Query: 886 QDGEAGRRAREVAFIH 901
            D + G R R+V  I+
Sbjct: 51  ADIQQGTRLRKVTQIN 66


>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
          Length = 411

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 63/209 (30%), Positives = 73/209 (34%), Gaps = 37/209 (17%)

Query: 148 PIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSC 207
           P ++  QRG   R APL  AA   AP   P+G  P        +P    L  A       
Sbjct: 30  PQRVPGQRGRGARAAPLVPAASASAPQRGPSGILPAA------EPTICSLHQAWG----- 78

Query: 208 GPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAER 267
           GP   A    PA    G   PGP        P P  +    P      GP+PGP      
Sbjct: 79  GPGCRAQKGIPAALSPG---PGP-----IPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSP 130

Query: 268 RSLPFTTP-PGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYP---SEELSGPSPRRM 323
              P   P  GP Q      P  FRG     PGP      P P P   S   SGP+P  +
Sbjct: 131 IPAPIPGPISGPVQI-----PGPFRGPI---PGPISG---PAPIPGPISGPFSGPNPGPI 179

Query: 324 GGYYAGEVR---TFPIQEPPSRSYYGEAP 349
            G   G +    + PI  P S    G  P
Sbjct: 180 PGPNPGPIPGPISGPIPGPISVPIPGPIP 208


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 65/224 (29%), Positives = 77/224 (34%), Gaps = 28/224 (12%)

Query: 65   ETLPEPPPPESAVPRARTREAEPRRRARSKSA--PRAPPGLTPAPASP------PVLPRR 116
            E  PEPPPP S            RRR  S+ A  P  PP   PA   P      P LP  
Sbjct: 1158 EAGPEPPPPLSVYHNGT---GTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPP 1214

Query: 117  GREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEP 176
              EA++ A+   SP+     P  +   +     K  P    PG  +P    A    PP  
Sbjct: 1215 EGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPL---PGPGSPEVKRAHGTPPPVS 1271

Query: 177  PAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALS 236
            P  P P        KP  AV   A   S S GP+ A   AR  P         P  +  S
Sbjct: 1272 PKPPPPPTA----PKPVKAV---AGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGAS 1324

Query: 237  RTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQ 280
                PS      P A     P   PR  A   +     PP P +
Sbjct: 1325 PAKPPS------PGAPALHVPAKPPR-AAAAAAAAAAAPPAPPE 1361



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 138/650 (21%), Positives = 202/650 (31%), Gaps = 141/650 (21%)

Query: 58   ALDGPAMETLPEPPPPESAVPRARTREAEPRRRARS-------KSAPRAPPGLTPAPASP 110
            A  GPA   +P   P     P A      P++RA S        S P     L PA A P
Sbjct: 847  AAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGP 906

Query: 111  PVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGR 170
                +R      + RA A   +       R+ +  + P K  P    P R +   A+A  
Sbjct: 907  YATVQRRVGRSHSVRAPAGADKN----VNRSQSFAVRPRKKGPPPPPPKRSSSALASANL 962

Query: 171  CAPPEPPAGP-----APHVRCRL--------------DIKPDDAVLQHATRGSRSCGPTE 211
               P P A P         +CR                +K   A+L+ ++ G        
Sbjct: 963  ADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGG------- 1015

Query: 212  AAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLP 271
                AR  P+ H    P PR      +P P           + +   PG      RR+L 
Sbjct: 1016 GGRAARRPPEGH----PTPR----PASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTL- 1066

Query: 272  FTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEV 331
                 GP          G   +    PG + D   P P+  +      PR      AG  
Sbjct: 1067 ----SGPV--------TGLLATARRGPGESAD---PGPFVEDGTGRQRPRGPSKGEAG-- 1109

Query: 332  RTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLART 391
                ++ PP       A          R +  +       +   TE        D + R 
Sbjct: 1110 ----VEGPPLAKVEASATL-------KRRIRAKQNQQENVKFILTES-------DTVKR- 1150

Query: 392  YPHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDN 451
               P++    A  GP P             P L+ +H GTGT   R A++     ++   
Sbjct: 1151 --RPKAKEREA--GPEP------------PPPLSVYHNGTGTVRRRPASE-----QAGPP 1189

Query: 452  ILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPV---VVNLSTSPRRYAALSL 508
             L P P   +P     ++   L      P G + +  +PPV    V     P+   + + 
Sbjct: 1190 ELPPPPPPAEPPPTDLAHLPPL----PPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTP 1245

Query: 509  SETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDG 568
            +   +   G     + R     P ++          +P      LP G   P P      
Sbjct: 1246 TSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSP-----A 1300

Query: 569  PTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPAL-- 626
            P+  RQ                  P A  A  P      P       ++P   GAPAL  
Sbjct: 1301 PSPARQ------------------PPAALAKPPGT----PPSLGASPAKPPSPGAPALHV 1338

Query: 627  --APPRSPPASAGSAEEPAAPGEAADASPEPSADEDDLMTCSNARCRRTE 674
               PPR+  A+A +A  P AP E A          ++   C  A  +  E
Sbjct: 1339 PAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVE 1388



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/194 (28%), Positives = 67/194 (34%), Gaps = 39/194 (20%)

Query: 39   PAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESA-------VPRAR-----TREAE 86
            PAEP P +  H      L  L  P  E      PP S        VP+ +     T +  
Sbjct: 1197 PAEPPPTDLAH------LPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKV 1250

Query: 87   PRRRARSKSAPRA---PPGLTPAPASPPVLPR--RGREAQRAARAEASPRREPAYPALRA 141
            P     S    RA   PP ++P P  PP  P+  +      +  A  SP   PA     A
Sbjct: 1251 PLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAA 1310

Query: 142  LANE--------LHPIKLQPQRGGPGRVAPL-------CAAAGRCAPPEPPAGPAPHVRC 186
            LA            P K  P  G P    P         AAA   APP PP G +P    
Sbjct: 1311 LAKPPGTPPSLGASPAK-PPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSA 1369

Query: 187  RLDIKPDDAVLQHA 200
            R  ++   A L  A
Sbjct: 1370 RQKLEETSACLAAA 1383



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 170/703 (24%), Positives = 213/703 (30%), Gaps = 150/703 (21%)

Query: 39   PAEPAPFNKRHCRSFDFLE---------ALDGPAMETLPEPPPPESAVP---RARTRE-A 85
            P EP P + +  +   F +         A+ GPA E  P    P S +P   RA TR+ +
Sbjct: 636  PPEPTPADCQSPKMTTFQDSELSDELQAAMTGPA-EVGPTTEKPSSHLPPTPRATTRQDS 694

Query: 86   EPRRRARSKSAPR-----APPGLT--------------PAPASPPVLPRRGREAQRAARA 126
                RAR  S+ +      PPG +              PAP +PP   R GR      RA
Sbjct: 695  SLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRA 754

Query: 127  EASP----RREPAYPALRALANELHPIKLQP----QRGGPGRVAPLCA-----------A 167
               P     R+   P          P K +P      GGP   AP  A            
Sbjct: 755  SVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPT 814

Query: 168  AGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRS----------CGPTEA-AHWA 216
                +P   P  P       +  +P +  +  A  G             C P EA A   
Sbjct: 815  ERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPG 874

Query: 217  RPAPQFHGLTVPGPRHMALSR----TPTPSDSYCADPRAFYCDGPL--PGPRDYAERRSL 270
            RP  + H L           R     P  +  Y    R       +  P   D    RS 
Sbjct: 875  RPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQ 934

Query: 271  PFTTPP---GPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPR-RMGGY 326
             F   P   GP        P   R S A +     D   P   P + L G   + R    
Sbjct: 935  SFAVRPRKKGP------PPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASD 988

Query: 327  YAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERD 386
             AG V T       S +   E     G   G R     P  H T RP   E     R   
Sbjct: 989  LAGSVDTGSAGSVKSIAAMLELSSIGG---GGRAARRPPEGHPTPRPASPEP---GRVAT 1042

Query: 387  VLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYS 446
            VLA         P       R  RTL                  +G     LAT  R   
Sbjct: 1043 VLASVKHKEAIGPGGEVVNRR--RTL------------------SGPVTGLLATARRGPG 1082

Query: 447  RSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSP-----EGRRPPVVVNLSTSPR 501
             S D    PGP  ED  GR R            PRG S      EG     V   +T  R
Sbjct: 1083 ESAD----PGPFVEDGTGRQR------------PRGPSKGEAGVEGPPLAKVEASATLKR 1126

Query: 502  RYAA---------LSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWE 552
            R  A           L+E+   ++    +         P +++  N      R  A    
Sbjct: 1127 RIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQA 1186

Query: 553  LPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRR 612
             P     PPP A P  PT      L  L  L         P  G+A +PA   + P+   
Sbjct: 1187 GPPELPPPPPPAEPP-PT-----DLAHLPPL--------PPPEGEARKPAKPPVSPK-PV 1231

Query: 613  LLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEP 655
            L    P   G+P     + P    GS E   A G     SP+P
Sbjct: 1232 LTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKP 1274


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 38/117 (32%), Positives = 42/117 (35%), Gaps = 25/117 (21%)

Query: 68  PEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAE 127
           P PPPP ++ P        P   AR + AP  PP   P  A PP  P R       A   
Sbjct: 289 PPPPPPHNSGP--------PPPPARGRGAPPPPPSRAPTAAPPPPPPSR----PSVAVPP 336

Query: 128 ASPRR--EPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAP 182
             P R   P  PAL + A             GP    P     G  APP PP  P P
Sbjct: 337 PPPNRMYPPPPPALPSSA-----------PSGPPPPPPSVLGVGPVAPPPPPPPPPP 382



 Score = 34.3 bits (77), Expect = 0.58
 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 15/77 (19%)

Query: 817 SVAVGPGTA----PPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPPPARSREPDMET 872
           SVAV P       PP  PALP+ AP    P       V   A  P  PPP     P    
Sbjct: 331 SVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPP---- 386

Query: 873 LILTPPPGTAGLDQDGE 889
               PPP   GL  DG+
Sbjct: 387 ----PPP---GLPSDGD 396


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 113/440 (25%), Positives = 149/440 (33%), Gaps = 78/440 (17%)

Query: 73  PESAVPRARTREAEPRRRARSKSAPRAPP--GLTPAPASPPVLPRRGREAQRAARAEASP 130
           P  A P   T + +PR+ A S   P  PP    TPA  +       G +AQ     EA P
Sbjct: 6   PRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQP 65

Query: 131 RR----EPAYPALRALANELHPIKLQPQRGGPGRVAPLCA---AAGRCAPPEPPAG---- 179
           R+    E   P+LR  A    P K    +  PGR +PL A    AGR A   PP      
Sbjct: 66  RQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGR-SPLQAPSRLAGR-AEGSPPQRYILG 123

Query: 180 -PAPHVRCRLDIKPDDAVLQHA-------TRGSRSCGPTEAA---HWARPAPQ---FHGL 225
             +   +  LD  P++  L+ A        +G  +  P         A+PA +   FH  
Sbjct: 124 IASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRC 183

Query: 226 TVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTE 285
               P     +   +PS    A PR      P PGP        L   + P         
Sbjct: 184 FQEPPSSFTSTNYTSPS----ATPRP-----PAPGPPQSRGTSPLQPGSYPEYQASGADS 234

Query: 286 EPQGFRGSFAASPGPTFDA--YYPRPYPSEELSGPSPRRMG------GYYAGEVRTFPIQ 337
            P     SF   PG  F      P P P     G SPR +         +    + FP  
Sbjct: 235 WPPAAENSF---PGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPAD 291

Query: 338 EPPSRSYYGEAPRAYGLPY----------GPRY-VPEEPRAHSTARPFYTEDFGRYRERD 386
                   G    A+  P           GP Y +P +P A S    +  +  G  R  D
Sbjct: 292 VAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQP-APSPLPCYQGQPGGLNRHSD 350

Query: 387 VLARTYPHPRSSPAWADWGPRPY---------RTLQVVPPSDPDPLLASWHGGTGTSPPR 437
           +         SSP  A   PRP+         + L   PPS  D  L S  G   + P R
Sbjct: 351 LSGAL-----SSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDG-LGSTRGPPSSLPQR 404

Query: 438 LATDSRHYSRSWDNILAPGP 457
                 + +   D   +PGP
Sbjct: 405 HFPGQAYRASGVDT--SPGP 422



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 33/120 (27%), Positives = 44/120 (36%), Gaps = 21/120 (17%)

Query: 19   KVATPGPASKCSPCE--RSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESA 76
            K   PGPA   S     R+ + P +P    ++       L     P  +  P PPP E  
Sbjct: 3791 KGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQ- 3849

Query: 77   VPRARTREAEP----RRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRR 132
                  R+AEP    R+    K+ P+  P L P        P+RG     A  AE    R
Sbjct: 3850 ------RKAEPGHTQRKDRLGKAFPQGRPLLRP--------PKRGTAVHGAEPAEPHTHR 3895


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 111/465 (23%), Positives = 156/465 (33%), Gaps = 90/465 (19%)

Query: 76  AVPRART---REAEPRRRARSKSAPRAP-PGLTPAPASPPVLPRRGREAQRAARAEASPR 131
           AVP ++T    E+  RR +R         P +TP P    ++     + ++  + E    
Sbjct: 358 AVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVE 417

Query: 132 REPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIK 191
            EP   AL A A+          R  P       AAA    P       +P ++ +   K
Sbjct: 418 EEPF--ALGAEASNFQQEPAPRDRASP-------AAAEEVVPEWASCLKSPRIQAKPKPK 468

Query: 192 PDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMA-LSRTPTPSDSYCADPR 250
           P+  + + + +G        A  +AR   +     +    H   L+R P+P+ S    P 
Sbjct: 469 PNQNLSEASGKG--------AELYARRQSRMEKYVIESSSHTPELARCPSPTMSL---PS 517

Query: 251 AFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYP-RP 309
           ++      PG    A R   P  TPP      Y  E    R      P PT    Y  RP
Sbjct: 518 SWKYPTNAPGAFRVASRS--PARTPPASLYHGYLPENGVLR------PEPTKQPPYQLRP 569

Query: 310 Y-----PSEELSGPSPRRMG-----------GYYAGEVRTFPIQEPPSRSYYGE------ 347
                 P +E +  SPR                  G +   P    PSRS  G       
Sbjct: 570 SLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQ 629

Query: 348 ---APRAYGLPYGPRYVPEEP------RAHSTARP-FYTEDFGRYRE--RDVLARTYPH- 394
               P A   PYG    P  P      RA    RP F T + G   +  R+ L  + P  
Sbjct: 630 DSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWT 689

Query: 395 ------PRSSPAWAD---WGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHY 445
                 P S   W     W P    ++   PP  P P ++        SP R  T++R  
Sbjct: 690 PGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPP 749

Query: 446 SRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRP 490
           SR    +LA            R+  N   R+   PR    E  RP
Sbjct: 750 SRQLQALLA------------RNIINAARRKSASPRSAGAENPRP 782



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 58/237 (24%), Positives = 76/237 (32%), Gaps = 35/237 (14%)

Query: 20  VATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPP------- 72
           ++   P+   SP  +   RP+    F+ R+      +EA D    E+LP  PP       
Sbjct: 645 ISPVSPSRAWSPRAKQAPRPS----FSTRNAG----IEAQD--RRESLPTSPPWTPGASR 694

Query: 73  -PESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPR 131
            P S          EP R +   S    PP L P P   P    R     R       P 
Sbjct: 695 PPSSLDGWVSPGPWEPGRGSSMSS----PPPLPPPPPMSPSWSERSVSPLRPETEARPPS 750

Query: 132 REPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIK 191
           R+      R + N        P+  G     P         PP PP  P P +R     +
Sbjct: 751 RQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAP-PPPPPPPPPPPRMRSPQPAR 809

Query: 192 PDDAVLQHAT-----RGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSD 243
           P  A +  A      R     GP+       P P         PR     R+PT SD
Sbjct: 810 PGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLP-------APPRPFLYRRSPTDSD 859



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 83/336 (24%), Positives = 113/336 (33%), Gaps = 74/336 (22%)

Query: 27  SKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRARTREAE 86
           +K SP   S A+P+           S D +  L   A+   P  P P  + P   T    
Sbjct: 581 AKVSPRAASPAKPS-----------SLDLVPNLPKGALPPSPALPRPSRSSPGLYT---S 626

Query: 87  PRRRARSKSAPRAPPGLTPAPASPP-VLPRRGREAQRA------ARAEASPRRE--PAYP 137
           P + +   +A   P G   +P SP      R ++A R       A  EA  RRE  P  P
Sbjct: 627 PGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP 686

Query: 138 ALRALANELHPIKLQ----PQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPD 193
                A+   P  L     P    PGR + + +      PP PP  P+   R    ++P+
Sbjct: 687 PWTPGASR-PPSSLDGWVSPGPWEPGRGSSMSSPPP--LPPPPPMSPSWSERSVSPLRPE 743

Query: 194 DAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFY 253
                           TEA     P+ Q   L      + A  ++ +P  +   +PR F 
Sbjct: 744 ----------------TEARP---PSRQLQALLARNIINAARRKSASPRSAGAENPRPFS 784

Query: 254 CDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSE 313
                P P         P   PP P        PQ  R   AA PG  F      P P+ 
Sbjct: 785 PPRAPPPP---------PPPPPPPPRM----RSPQPARPGSAAVPGAAFAPIPRSPLPAG 831

Query: 314 ELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAP 349
             S  SPR             P+  PP    Y  +P
Sbjct: 832 PSSCTSPRS------------PLPAPPRPFLYRRSP 855



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 41/154 (26%), Positives = 50/154 (32%), Gaps = 33/154 (21%)

Query: 65  ETLPEPPPPE-------SAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRG 117
           ET   PP  +       + +  AR + A PR        P +PP   P P  PP  P R 
Sbjct: 743 ETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRM 802

Query: 118 REAQRAARAEASPRREPAYPALRALAN-ELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEP 176
           R  Q            PA P   A+      PI   P   GP            C  P  
Sbjct: 803 RSPQ------------PARPGSAAVPGAAFAPIPRSPLPAGP----------SSCTSPRS 840

Query: 177 --PAGPAPHVRCRLDIKPDDAVLQHATRGSRSCG 208
             PA P P +  R      D  L     G++S G
Sbjct: 841 PLPAPPRPFL-YRRSPTDSDVSLDSEDSGAKSPG 873



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 52/213 (24%), Positives = 74/213 (34%), Gaps = 21/213 (9%)

Query: 453 LAPGPRREDPLGRGRSYENLLGREVREPRGVSPE--GRRPPVVVNLSTSPRRYAA----L 506
           L P P    P           G++  +P  VSP   G   PV  + + SPR   A     
Sbjct: 607 LPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSF 666

Query: 507 SLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAP 566
           S     +  + R  E L  +   TP  +   + L     P    WE   G +   P   P
Sbjct: 667 STRNAGIEAQDRR-ESLPTSPPWTPGASRPPSSLDGWVSPGP--WEPGRGSSMSSPPPLP 723

Query: 567 DGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAA-DCLGPQLRRLLDSRPAGSG--- 622
             P      S   +  L  +   ++RP + Q     A + +    R+    R AG+    
Sbjct: 724 PPPPMSPSWSERSVSPLRPET--EARPPSRQLQALLARNIINAARRKSASPRSAGAENPR 781

Query: 623 ------APALAPPRSPPASAGSAEEPAAPGEAA 649
                 AP   PP  PP     + +PA PG AA
Sbjct: 782 PFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAA 814


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 63/243 (25%), Positives = 90/243 (37%), Gaps = 31/243 (12%)

Query: 23  PGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRAR- 81
           PGPA            PA+P+   K   +    ++    P   T P   P   A P A+ 
Sbjct: 326 PGPAKP----------PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375

Query: 82  TREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRA 141
           T   +P        A   PPG+   PA  P        A+   +   +P+     P L++
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQP------GPAKPPTQQVGTPKPLAQQPGLQS 429

Query: 142 LANELHPIKLQPQRGGPGRVAPLCAAAGRCA-----PPEPPA---GPA-PHVRCRLDIKP 192
            A    P K   Q+ GPG++    A  G+ +     P +PP+   GPA P  +     KP
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489

Query: 193 DDAVLQHATRGSRSCG----PTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCAD 248
                  A   S+  G    P +    A+P+PQ  G T P P     S  P+      A 
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAK 548

Query: 249 PRA 251
           P A
Sbjct: 549 PSA 551



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 73/344 (21%), Positives = 119/344 (34%), Gaps = 53/344 (15%)

Query: 72  PPESAVPRARTREAEPRRRARSKSA---PRAPPGLTPAPASPPVLPRRGREAQRAARAEA 128
           P +    R +T++A+  R    K +   P  PP   P P  PP   + G E     +++ 
Sbjct: 273 PLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA-QQPGHE-----KSQP 326

Query: 129 SPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPP------EPPAGPAP 182
            P + PA P+         P  ++P    PG   P     G   PP      E P+   P
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386

Query: 183 HVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPS 242
             +     +P       A +   +  PT+     +P  Q  GL  P       ++ P P+
Sbjct: 387 GPKAL--AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP-------AKAPGPT 437

Query: 243 DSYCADPRAFYCDGPLPGPRDYAERRSLPFTTP---PGPTQFFYTEEPQGFRGSFAASPG 299
            +    P          GP   + +++ P   P   PGP +      PQ         PG
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAK----PPPQ--------QPG 485

Query: 300 PTFDAYYPRPYPSEELSGPSPRRMGG------YYAGEVRTFPIQEPPSRSYYGEAPRAYG 353
           P       +P P +  S   P +  G         G  +  P Q+P S     + P +  
Sbjct: 486 PA------KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP-QQPGSTKPPSQQPGS-A 537

Query: 354 LPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRS 397
            P   +  P +P A  + +P      G+  +   ++ +   P S
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 77/319 (24%), Positives = 109/319 (34%), Gaps = 59/319 (18%)

Query: 66  TLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPP----GLT------PAPASPPVLPR 115
           +LP P  P    P      A+     +S+  P  PP    GLT      P    PPV P 
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356

Query: 116 RGRE--------AQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGP--------G 159
              +        A+  A+   S +     P  +ALA      K   Q+ GP        G
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416

Query: 160 RVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSC---GPTEAAHWA 216
              PL    G  +P + P      V+      P     Q A  G  S    GPT      
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQ---QPGPGKIPAQQAGPGKTSAQQTGPT------ 467

Query: 217 RPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPP 276
           +P  Q  G   P P+    ++ P P     A P +       P P+        P    P
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAK-PPPQQPGSAKPPSQQPGSTKPPPQQ-------PGPAKP 519

Query: 277 GPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPI 336
            P Q   T+ P    GS   S          +P P++  +  S + +    +G+    P+
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSA--------QQPSPAKPSAQQSTKPVSQTGSGK----PL 567

Query: 337 QEPPSRSYYGEAPRAYGLP 355
           Q PP+ S   + P + GLP
Sbjct: 568 Q-PPTVSPSAKQPPSQGLP 585



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 79/376 (21%), Positives = 119/376 (31%), Gaps = 97/376 (25%)

Query: 60   DGPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGRE 119
            D    + L + P P+   P  +         A++K  P A     PAP   P +P    E
Sbjct: 687  DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP---SE 743

Query: 120  AQRAARAEASPRR------------------EPAYPA--LRALANELHPIKLQPQRGGPG 159
              +A  A+  P++                  +P  P+  +++ A E     L+     P 
Sbjct: 744  QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803

Query: 160  RVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCG----------- 208
            +  P      + +P +  A P P          D  ++ H    S S G           
Sbjct: 804  QSFP--PTGEKVSPFDSKAIPRP--------ASDSKIISHPGPSSESKGQKQVDPVQKKE 853

Query: 209  -PTEAAHWARPAPQFHGL-----TVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPR 262
             P +A     P P    +     T PGPR  A    PTP  S              P P+
Sbjct: 854  EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS--------------PKPQ 899

Query: 263  DYAERRSL--------PFTTPPGPTQFFYTEEPQGFRGSF----------AASPGPTFDA 304
            + + R SL        P + P  P Q   T +  GF  S           A  PGP   +
Sbjct: 900  EQSRRFSLNLGSITDAPKSQPTTP-QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958

Query: 305  -------YYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYG 357
                     P P       GP P+  G       ++ P+++        +AP A  L   
Sbjct: 959  GPGAPMKQAPAPSQPPTSQGP-PKSTGQAPPAPAKSIPVKKET------KAPAAEKLEPK 1011

Query: 358  PRYVPEEPRAHSTARP 373
                P   R  +  +P
Sbjct: 1012 AEQAPTVKRTETEKKP 1027



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 47/218 (21%), Positives = 78/218 (35%), Gaps = 13/218 (5%)

Query: 456 GPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTE 515
           GP R DPL +  + +++  ++  + +   P G   P+     T    +A L L   +   
Sbjct: 224 GPGR-DPLQQDGTPKSISSQQPEKIKS-QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281

Query: 516 KGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQR 575
           + +  + + R   V P +            P     + PG     P  A P    SG  +
Sbjct: 282 QTKQAD-IVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340

Query: 576 SLEQLDELITDLVIDSRPTAGQASEPAADCLGPQ---LRRLLDSRPAGS--GAPALAPPR 630
            L Q    +   V     T     +P A  LGP     ++    +P+    G  ALA P 
Sbjct: 341 PLAQQPGTVKPPVQPPGTT-----KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395

Query: 631 SPPASAGSAEEPAAPGEAADASPEPSADEDDLMTCSNA 668
               +      PA P      +P+P A +  L + + A
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA 433



 Score = 30.4 bits (67), Expect = 8.4
 Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 35/158 (22%)

Query: 25   PASKCSPCERSVAR-PAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRARTR 83
            PAS+      SV+  PA+P PF +          +LD  A    P PPPP    P     
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRS--------SSLDISAQPPPPPPPPPPPPPP----- 2418

Query: 84   EAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALA 143
                            PP   P P  PP  P+     ++     ASP    A P   A+ 
Sbjct: 2419 ----------------PPPPPPPPLPPPTSPKPTILPKKKLTV-ASP-VTTATPLFDAVT 2460

Query: 144  NELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPA 181
              L    +    G P  V  +C  A    PP+P + P+
Sbjct: 2461 T-LETTAVLRSNGLP--VTRICTTAPPPVPPKPSSIPS 2495


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 63/243 (25%), Positives = 90/243 (37%), Gaps = 31/243 (12%)

Query: 23  PGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRAR- 81
           PGPA            PA+P+   K   +    ++    P   T P   P   A P A+ 
Sbjct: 326 PGPAKP----------PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375

Query: 82  TREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRA 141
           T   +P        A   PPG+   PA  P        A+   +   +P+     P L++
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQP------GPAKPPTQQVGTPKPLAQQPGLQS 429

Query: 142 LANELHPIKLQPQRGGPGRVAPLCAAAGRCA-----PPEPPA---GPA-PHVRCRLDIKP 192
            A    P K   Q+ GPG++    A  G+ +     P +PP+   GPA P  +     KP
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489

Query: 193 DDAVLQHATRGSRSCG----PTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCAD 248
                  A   S+  G    P +    A+P+PQ  G T P P     S  P+      A 
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAK 548

Query: 249 PRA 251
           P A
Sbjct: 549 PSA 551



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 73/344 (21%), Positives = 119/344 (34%), Gaps = 53/344 (15%)

Query: 72  PPESAVPRARTREAEPRRRARSKSA---PRAPPGLTPAPASPPVLPRRGREAQRAARAEA 128
           P +    R +T++A+  R    K +   P  PP   P P  PP   + G E     +++ 
Sbjct: 273 PLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA-QQPGHE-----KSQP 326

Query: 129 SPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPP------EPPAGPAP 182
            P + PA P+         P  ++P    PG   P     G   PP      E P+   P
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386

Query: 183 HVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPS 242
             +     +P       A +   +  PT+     +P  Q  GL  P       ++ P P+
Sbjct: 387 GPKAL--AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP-------AKAPGPT 437

Query: 243 DSYCADPRAFYCDGPLPGPRDYAERRSLPFTTP---PGPTQFFYTEEPQGFRGSFAASPG 299
            +    P          GP   + +++ P   P   PGP +      PQ         PG
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAK----PPPQ--------QPG 485

Query: 300 PTFDAYYPRPYPSEELSGPSPRRMGG------YYAGEVRTFPIQEPPSRSYYGEAPRAYG 353
           P       +P P +  S   P +  G         G  +  P Q+P S     + P +  
Sbjct: 486 PA------KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP-QQPGSTKPPSQQPGS-A 537

Query: 354 LPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRS 397
            P   +  P +P A  + +P      G+  +   ++ +   P S
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 77/319 (24%), Positives = 109/319 (34%), Gaps = 59/319 (18%)

Query: 66  TLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPP----GLT------PAPASPPVLPR 115
           +LP P  P    P      A+     +S+  P  PP    GLT      P    PPV P 
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356

Query: 116 RGRE--------AQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGP--------G 159
              +        A+  A+   S +     P  +ALA      K   Q+ GP        G
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416

Query: 160 RVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSC---GPTEAAHWA 216
              PL    G  +P + P      V+      P     Q A  G  S    GPT      
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQ---QPGPGKIPAQQAGPGKTSAQQTGPT------ 467

Query: 217 RPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPP 276
           +P  Q  G   P P+    ++ P P     A P +       P P+        P    P
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAK-PPPQQPGSAKPPSQQPGSTKPPPQQ-------PGPAKP 519

Query: 277 GPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPI 336
            P Q   T+ P    GS   S          +P P++  +  S + +    +G+    P+
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSA--------QQPSPAKPSAQQSTKPVSQTGSGK----PL 567

Query: 337 QEPPSRSYYGEAPRAYGLP 355
           Q PP+ S   + P + GLP
Sbjct: 568 Q-PPTVSPSAKQPPSQGLP 585



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 79/376 (21%), Positives = 119/376 (31%), Gaps = 97/376 (25%)

Query: 60   DGPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGRE 119
            D    + L + P P+   P  +         A++K  P A     PAP   P +P    E
Sbjct: 687  DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP---SE 743

Query: 120  AQRAARAEASPRR------------------EPAYPA--LRALANELHPIKLQPQRGGPG 159
              +A  A+  P++                  +P  P+  +++ A E     L+     P 
Sbjct: 744  QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803

Query: 160  RVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCG----------- 208
            +  P      + +P +  A P P          D  ++ H    S S G           
Sbjct: 804  QSFP--PTGEKVSPFDSKAIPRP--------ASDSKIISHPGPSSESKGQKQVDPVQKKE 853

Query: 209  -PTEAAHWARPAPQFHGL-----TVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPR 262
             P +A     P P    +     T PGPR  A    PTP  S              P P+
Sbjct: 854  EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS--------------PKPQ 899

Query: 263  DYAERRSL--------PFTTPPGPTQFFYTEEPQGFRGSF----------AASPGPTFDA 304
            + + R SL        P + P  P Q   T +  GF  S           A  PGP   +
Sbjct: 900  EQSRRFSLNLGSITDAPKSQPTTP-QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958

Query: 305  -------YYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYG 357
                     P P       GP P+  G       ++ P+++        +AP A  L   
Sbjct: 959  GPGAPMKQAPAPSQPPTSQGP-PKSTGQAPPAPAKSIPVKKET------KAPAAEKLEPK 1011

Query: 358  PRYVPEEPRAHSTARP 373
                P   R  +  +P
Sbjct: 1012 AEQAPTVKRTETEKKP 1027



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 47/218 (21%), Positives = 78/218 (35%), Gaps = 13/218 (5%)

Query: 456 GPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTE 515
           GP R DPL +  + +++  ++  + +   P G   P+     T    +A L L   +   
Sbjct: 224 GPGR-DPLQQDGTPKSISSQQPEKIKS-QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281

Query: 516 KGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQR 575
           + +  + + R   V P +            P     + PG     P  A P    SG  +
Sbjct: 282 QTKQAD-IVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340

Query: 576 SLEQLDELITDLVIDSRPTAGQASEPAADCLGPQ---LRRLLDSRPAGS--GAPALAPPR 630
            L Q    +   V     T     +P A  LGP     ++    +P+    G  ALA P 
Sbjct: 341 PLAQQPGTVKPPVQPPGTT-----KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395

Query: 631 SPPASAGSAEEPAAPGEAADASPEPSADEDDLMTCSNA 668
               +      PA P      +P+P A +  L + + A
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA 433



 Score = 30.4 bits (67), Expect = 8.4
 Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 35/158 (22%)

Query: 25   PASKCSPCERSVAR-PAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRARTR 83
            PAS+      SV+  PA+P PF +          +LD  A    P PPPP    P     
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRS--------SSLDISAQPPPPPPPPPPPPPP----- 2418

Query: 84   EAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALA 143
                            PP   P P  PP  P+     ++     ASP    A P   A+ 
Sbjct: 2419 ----------------PPPPPPPPLPPPTSPKPTILPKKKLTV-ASP-VTTATPLFDAVT 2460

Query: 144  NELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPA 181
              L    +    G P  V  +C  A    PP+P + P+
Sbjct: 2461 T-LETTAVLRSNGLP--VTRICTTAPPPVPPKPSSIPS 2495


>gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo
           sapiens]
          Length = 398

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 68/250 (27%), Positives = 87/250 (34%), Gaps = 22/250 (8%)

Query: 79  RARTREAEPRRRARSKSAPRAPPGLT-PAPASPPVLPRRGREAQRAARAEASPRREPAYP 137
           + R + A P R+ R +  P+ PPG + P+         R   A+    A  S R  P  P
Sbjct: 123 QGRVQGAAPGRKLRGE--PKTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPP 180

Query: 138 ALRALANE---LHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPA-------GPAPHVRCR 187
           A    A     L P +         R  P C    R  PP  P         P P VR R
Sbjct: 181 ARLPPAPPGPLLRPARPPRPYFPRPRTPPTCEPPSRKLPPPLPLCRSRWVLAPPPPVRPR 240

Query: 188 LDIKPDDAVLQHAT--RGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSY 245
           L +      L+ A   RGSR+     A    R A     LT+      A       S+  
Sbjct: 241 LRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQ 300

Query: 246 CADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAY 305
            A  RAF    PLP P  +    SLP     G        +P+  R + A    P     
Sbjct: 301 AAPTRAFCSADPLPRPPSFVP--SLPSPQAQGQA----VRQPRLLRAALARG-APRGRTP 353

Query: 306 YPRPYPSEEL 315
            PRP P+  L
Sbjct: 354 SPRPGPAPAL 363


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,411,248
Number of Sequences: 37866
Number of extensions: 3695007
Number of successful extensions: 32363
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 1233
Number of HSP's that attempted gapping in prelim test: 22296
Number of HSP's gapped (non-prelim): 10168
length of query: 976
length of database: 18,247,518
effective HSP length: 112
effective length of query: 864
effective length of database: 14,006,526
effective search space: 12101638464
effective search space used: 12101638464
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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