BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo sapiens] (682 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo s... 1344 0.0 gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo s... 1339 0.0 gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens] 148 2e-35 gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 44 6e-04 gi|87299628 biorientation of chromosomes in cell division 1-like... 43 0.001 gi|37595553 ring finger protein 111 [Homo sapiens] 42 0.002 gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 42 0.002 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 41 0.004 gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 41 0.004 gi|34452686 ring finger protein, LIM domain interacting [Homo sa... 40 0.005 gi|34452684 ring finger protein, LIM domain interacting [Homo sa... 40 0.005 gi|83367077 mucin 16 [Homo sapiens] 40 0.005 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 40 0.007 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 40 0.007 gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 40 0.009 gi|24431975 hypothetical protein LOC26148 [Homo sapiens] 40 0.009 gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 39 0.012 gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 39 0.012 gi|45269141 multimerin 1 [Homo sapiens] 39 0.016 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 39 0.016 gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens] 38 0.027 gi|18379328 WW domain-containing adapter with a coiled-coil regi... 38 0.035 gi|18379332 WW domain-containing adapter with a coiled-coil regi... 38 0.035 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 38 0.035 gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 37 0.060 gi|11225260 DNA topoisomerase I [Homo sapiens] 37 0.079 gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 37 0.079 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 37 0.079 gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens] 37 0.079 gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens] 37 0.079 >gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo sapiens] Length = 682 Score = 1344 bits (3478), Expect = 0.0 Identities = 682/682 (100%), Positives = 682/682 (100%) Query: 1 MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTS 60 MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTS Sbjct: 1 MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTS 60 Query: 61 EDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKP 120 EDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKP Sbjct: 61 EDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKP 120 Query: 121 KDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRG 180 KDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRG Sbjct: 121 KDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRG 180 Query: 181 QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 240 QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK Sbjct: 181 QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 240 Query: 241 FVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVK 300 FVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVK Sbjct: 241 FVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVK 300 Query: 301 TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPK 360 TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPK Sbjct: 301 TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPK 360 Query: 361 ETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTE 420 ETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTE Sbjct: 361 ETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTE 420 Query: 421 KVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENII 480 KVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENII Sbjct: 421 KVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENII 480 Query: 481 AIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVD 540 AIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVD Sbjct: 481 AIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVD 540 Query: 541 VDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQ 600 VDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQ Sbjct: 541 VDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQ 600 Query: 601 SVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRE 660 SVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRE Sbjct: 601 SVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRE 660 Query: 661 TDAFVCRPNAALCRVYYEADTT 682 TDAFVCRPNAALCRVYYEADTT Sbjct: 661 TDAFVCRPNAALCRVYYEADTT 682 >gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo sapiens] Length = 683 Score = 1339 bits (3466), Expect = 0.0 Identities = 682/683 (99%), Positives = 682/683 (99%), Gaps = 1/683 (0%) Query: 1 MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSS-RDQRVVT 59 MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSS RDQRVVT Sbjct: 1 MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVT 60 Query: 60 SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 119 SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK Sbjct: 61 SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 120 Query: 120 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 179 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR Sbjct: 121 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 180 Query: 180 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT 239 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT Sbjct: 181 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT 240 Query: 240 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV 299 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV Sbjct: 241 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV 300 Query: 300 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP 359 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP Sbjct: 301 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP 360 Query: 360 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT 419 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT Sbjct: 361 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT 420 Query: 420 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI 479 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI Sbjct: 421 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI 480 Query: 480 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV 539 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV Sbjct: 481 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV 540 Query: 540 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL 599 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL Sbjct: 541 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL 600 Query: 600 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR 659 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR Sbjct: 601 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR 660 Query: 660 ETDAFVCRPNAALCRVYYEADTT 682 ETDAFVCRPNAALCRVYYEADTT Sbjct: 661 ETDAFVCRPNAALCRVYYEADTT 683 >gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens] Length = 745 Score = 148 bits (373), Expect = 2e-35 Identities = 130/504 (25%), Positives = 226/504 (44%), Gaps = 72/504 (14%) Query: 185 SKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVST 244 SK+ S +KP+ VK+ + P TK + + VK + + Sbjct: 287 SKVQSSKKPV-VKNIKDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPS------- 338 Query: 245 TSQNTQLVRPPIRSHHSNTRDTVKQG---ISRTSANVTIRKGPHEKELL---QSKTALSS 298 L++ + H N + K I +TS + K ++ L + +A+ S Sbjct: 339 ------LLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQKSKAISQRPNLTVGRFNSAIPS 392 Query: 299 VKTSSSQGIIRNKTLSRSIASEVIARPASLSN----DKLMEKSEPVDQRRHTAGKAIVDS 354 + G NK + + + L + + K+ P Q T + Sbjct: 393 TPSIRPNGTSGNKHNNNGFQQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTN 452 Query: 355 RSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDE 414 + + K T+E+R+ +L EW+ KG+ KRPP + T+ + + SFW ++ +E+E Sbjct: 453 PNIKKKATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNI---SFWKSIEKEEE 509 Query: 415 QRL----FTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIE 470 ++ + K+NNT +ECLNLI G P +IL +++ +IP+A+K K+WIC A + Sbjct: 510 EKKAQLELSSKINNTLTECLNLIEGGVPSNEIL----NILSSIPEAEKFAKFWICKAKLL 565 Query: 471 PITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVK 530 + +I +YE+AI GA PI+E+R +++IL ++ + S V Sbjct: 566 ASKGTFD-VIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGI--------TSDSLVA 616 Query: 531 EVSIEDTGVDVDPEKLEMESKLHRNLLFQDC--EKEQDNKTKDPTHDVKTPNTETRTSCL 588 E SI T V+ +K+E + C KE++ T P + E Sbjct: 617 ETSI--TSVEELAKKMES---------VKSCLSPKEREQVTATP----RIAKAEQHNYPG 661 Query: 589 IKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCV 648 IK + P + + + +++KF+TPVRRS R++ S+ P+ML++H V Sbjct: 662 IKLQIGPIPRINGMPE----------VQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVV 711 Query: 649 SSLEQLTELGRETDAFVCRPNAAL 672 +SL++L E+ ET F+ R N AL Sbjct: 712 ASLDELLEV-EETKCFIFRRNEAL 734 >gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] Length = 1163 Score = 43.5 bits (101), Expect = 6e-04 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 14/164 (8%) Query: 59 TSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTH 118 T E Q Q KV + E+ R +ESK K+ KPS+ +S Sbjct: 749 TREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQ--SAA 806 Query: 119 KPKDSNQTPHLLLTEDDPQSQH----MTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPV 174 K KD +P + DP+++H T+SQ+ LK++S + T+ K ++ K+ Sbjct: 807 KEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQ-- 864 Query: 175 LGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQ 218 + + K +S K ++ K SS++ SA ++KP+ Sbjct: 865 ------KKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902 Score = 31.6 bits (70), Expect = 2.5 Identities = 52/252 (20%), Positives = 99/252 (39%), Gaps = 27/252 (10%) Query: 12 LPPSQRAQSAFKEQRRQKLK------EHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQ 65 LPPS + + E R +K E R+ +F+ +E E+LS + +D+ Sbjct: 659 LPPSSQTPK-YPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSE----PDDRYP 713 Query: 66 EGTKV-LKLKTKMADKENMK-RPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDS 123 K+ L L T++ K + P + + V KH + S HK +D Sbjct: 714 LIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDD 773 Query: 124 NQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIV 183 N+ P+++ KN++ K + + + + +K +L S G V Sbjct: 774 NRASE----SKKPKTED---------KNSAGHKPSSNRESSKQSAAKEKDLLPSPAGP-V 819 Query: 184 QSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVS 243 SK + + S +++ K S+ K T N+SS + + ++++K V Sbjct: 820 PSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVK 879 Query: 244 TTSQNTQLVRPP 255 + ++ PP Sbjct: 880 EKAPSSSSNCPP 891 >gi|87299628 biorientation of chromosomes in cell division 1-like [Homo sapiens] Length = 3051 Score = 42.7 bits (99), Expect = 0.001 Identities = 81/422 (19%), Positives = 155/422 (36%), Gaps = 68/422 (16%) Query: 24 EQRRQKLKEHLLRRKTL---FAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADK 80 E + ++KE L RK L A ++ + S + + Q +E +K ++ +K Sbjct: 550 EPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEK 609 Query: 81 ENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTE------- 133 E + E K+ V P KP+ L+ S V+D +K + + H T Sbjct: 610 EKISSSKELKH---VHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEG 666 Query: 134 ---------------------DDPQSQHMTLSQAFHLKNNSK---------KKQMTTEKQ 163 ++PQ Q TL HLK + KK++ + K+ Sbjct: 667 VQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKE 726 Query: 164 KQD----ANMPKKPVLGSYRGQIV-----QSKINSFRKPLQVKD--ESSAATKKLSATIP 212 K + + K V Y+G + +++++S K L+V++ + + KLS+ Sbjct: 727 KPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDK 786 Query: 213 KATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGIS 272 K + N ++V ++++ T +N + + + T + S Sbjct: 787 TERKSKHRNERKLSVLGKDGK---PVSEYIIKTDENVRKENNK-KERRLSAEKTKAEHKS 842 Query: 273 RTSANVTIRKG-----PHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPAS 327 R S++ I+K H L + + S K + + + + R S Sbjct: 843 RRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKS 902 Query: 328 LSNDKLMEKSEPVDQRR-----HTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLK 382 L +KL+ KS+ Q + T + ++ PK E+ K K +V Sbjct: 903 LLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVED 962 Query: 383 RP 384 +P Sbjct: 963 KP 964 >gi|37595553 ring finger protein 111 [Homo sapiens] Length = 986 Score = 42.0 bits (97), Expect = 0.002 Identities = 54/301 (17%), Positives = 111/301 (36%), Gaps = 23/301 (7%) Query: 11 QLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEG--- 67 +LP +R QR QK KE +L ++ ++ E+L+ R ++ S E Sbjct: 209 RLPCRKRFVKNNSSQRTQKQKERILMQR------KKREVLARRKYALLPSSSSSSENDLS 262 Query: 68 TKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTP 127 ++ + +++ +E+ N P PS + VVI+ Sbjct: 263 SESSSSSSTEGEEDLFVSASENHQNN-------PAVPSGSIDEDVVVIEASSTPQVTANE 315 Query: 128 HLLLTEDDPQSQHMTLSQAFHLKNN-SKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSK 186 + +T D + + +T+ +++ ++ + ++ A+ P++P S ++Q Sbjct: 316 EINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPL 375 Query: 187 INSFRK--PLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVST 244 + + L V ++ SA + +N S+ + S +A T + Sbjct: 376 RQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPS 435 Query: 245 TSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSS 304 T T + +S T ++ RT+++ GP L S S SS Sbjct: 436 TVSETSAT----LTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSS 491 Query: 305 Q 305 Q Sbjct: 492 Q 492 >gi|114431248 hypothetical protein LOC205717 [Homo sapiens] Length = 2245 Score = 41.6 bits (96), Expect = 0.002 Identities = 67/303 (22%), Positives = 111/303 (36%), Gaps = 34/303 (11%) Query: 93 TVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNN 152 T GKH + + P +++ T SNQ P + + +S + Sbjct: 627 TFGGKHLVHILPRPSSLSASNSTQTFSVTMSNQQPQTISLNGQLFALQPVMSSSGTTNQT 686 Query: 153 SKKKQMTTEKQKQDANMPKKP--VLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSAT 210 + T + + N+ L S I Q S + L + +++ T S T Sbjct: 687 PMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQ-LSISQPANSQTAANSQT 745 Query: 211 IPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSN-------- 262 A T++ V ++ S+ + +T VST+S NT P ++S N Sbjct: 746 TT-ANCVSLTTTAAPPVTTDSSATLASTYNLVSTSSMNTVACLPNMKSKRLNKKPGGRKH 804 Query: 263 ------------TRDTVKQGISRTSANVTIRKGPHEKELLQSKTA-LSSVKTSSSQGIIR 309 RD K T + + P LL+S A L SV S + + Sbjct: 805 LAANKSACPLNSVRDVSKLDCPNTEGSA---EPPCNDGLLESFPAVLPSVSVSQANSVSV 861 Query: 310 NKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTA---GKAIVDSRSAQP---KETS 363 + + S + S P S+S K EKS P Q T+ A S+ + P +ETS Sbjct: 862 SASHSLGVLSSESLIPESVSKSKSAEKSSPPSQESVTSEHFAMAAAKSKDSTPNLQQETS 921 Query: 364 EER 366 +++ Sbjct: 922 QDK 924 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 40.8 bits (94), Expect = 0.004 Identities = 109/579 (18%), Positives = 233/579 (40%), Gaps = 68/579 (11%) Query: 8 QDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEM-----LSSRDQRVVTSED 62 Q QL + QS +Q ++ L + + +K Q+ + ++ + ++ S++ Sbjct: 576 QVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKE 635 Query: 63 QVQEGTKVLKLKTKM---ADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 119 +V + +K KT++ A+ + A+ +N+ ++ + K EL T +D Sbjct: 636 KVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDK-QQELNKITTQLDQVT 694 Query: 120 PKDSNQTPHLLLTED---DPQSQHMTLSQ-------------AFHLKNNSKKKQMTTEKQ 163 K ++ H E + + ++++L Q A L+ + K+Q + Q Sbjct: 695 AKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQ 754 Query: 164 KQ---DANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDES--SAATKKLSATIPKATKPQ 218 +Q + ++ + S + ++ + ++S R LQ K E+ S K K Q Sbjct: 755 QQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQ 814 Query: 219 PVNTSSVTVKSNRS--SNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSA 276 T S K +N TT T Q ++ + + + S TVK +S+ S Sbjct: 815 DFETLSQETKIQHEELNNRIQTTV---TELQKVKMEKEALMTELS----TVKDKLSKVSD 867 Query: 277 NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 336 ++ K EKE + K A+ ++ + + + + + E SL +K E Sbjct: 868 SLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEK--EA 925 Query: 337 SEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAG 396 S + ++ + ++ +++ + EE++ + G LK+ Q E A Sbjct: 926 SHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQ------GNINELKQSSEQKKKQIE-AL 978 Query: 397 QNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDA 456 Q E + T E Q+ T+ +E KE I V N+ K+ Sbjct: 979 QGELKIAVLQKTELENKLQQQLTQAAQELAAE----------KEKISVLQNNYEKSQETF 1028 Query: 457 KKLVKYWI-----CLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKS-- 509 K+L + LA + + S +E +++ ++ +++ I I ++ T K+ Sbjct: 1029 KQLQSDFYGRESELLATRQDLKS-VEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATL 1087 Query: 510 -QEKANLGENMEKSCASKEEV-KEVSIEDTGVDVDPEKL 546 Q+ A + +++ C + +++ KE S+++ + + KL Sbjct: 1088 EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKL 1126 >gi|62241003 cardiomyopathy associated 5 [Homo sapiens] Length = 4069 Score = 40.8 bits (94), Expect = 0.004 Identities = 76/393 (19%), Positives = 158/393 (40%), Gaps = 45/393 (11%) Query: 14 PSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKL 73 P + ++ + + +LK+ + +L ++E ++ R +D ++ + L Sbjct: 2413 PVEESKGSLIDFSEDRLKKEMQNPTSLKISEEETKL---RSVSPTEKKDNLENRSYTLAE 2469 Query: 74 KTKMADKENMKRPAESKNNTVVGKHCIPL-KPSNELTNS---TVVIDTHKPKDSNQTPHL 129 K +A+K+N P E +++ +GK I L S EL S + ++ +D N+ P + Sbjct: 2470 KKVLAEKQNSVAPLELRDSNEIGKTQITLGSRSTELKESKADAMPQHFYQNEDYNERPKI 2529 Query: 130 LLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINS 189 ++ + + + +Q + L K+++ +M ++ + S + +++ S Sbjct: 2530 IVGSEKEKGEEKE-NQVYVLSEGKKQQEHQPYSVNVAESMSRESDI-SLGHSLGETQSFS 2587 Query: 190 FRKPLQVKDESSAATKKLSATIPKA----TKPQPVNTSSVTVKSNRSSNMTATT-----K 240 K V ++S A + I +A T+P P+ S V V+ ++ A + + Sbjct: 2588 LVKATSVTEKSEAMLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLPVALSCRDEIE 2647 Query: 241 FVSTTSQNTQLVRPPIRS--HHSN------------------TRDTVKQGISRTSANVTI 280 S + + ++ R HS T++TVKQG + Sbjct: 2648 NHSLSQEGNLVLEKSSRDMPDHSEEKEQFRESELSKGGSVDITKETVKQGFQEKAVGTQP 2707 Query: 281 RKGPHEKELLQ-SKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEP 339 R K L++ +KT L V + + I N +LS+ + V+ + + D EK + Sbjct: 2708 RPLEESKVLVEKTKTFLPVVLSCHDE--IENHSLSQE-GNLVLEKSSRDMPDHSEEKEQF 2764 Query: 340 VDQRRHTAGKAIVDSRSAQ---PKETSEERKAR 369 + G + S + P + SE AR Sbjct: 2765 KESELWKGGSVDITKESMKEGFPSKESERTLAR 2797 Score = 33.9 bits (76), Expect = 0.51 Identities = 40/183 (21%), Positives = 72/183 (39%), Gaps = 10/183 (5%) Query: 36 RRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVV 95 ++ LF+ ++E L S ++ + S +V E L L K+ S+N + Sbjct: 1494 KQDLLFSTVCDSERLVSSQKKSLMSTSEVLEPEHELPLSLWGEIKKKETELPSSQNVSPA 1553 Query: 96 GKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKK 155 KH IP E +S+ ++ S P LLL DD + +S S+K Sbjct: 1554 SKHIIPKGKDEETASSSPELEN---LASGLAPTLLLLSDDKNKPAVEVSSTAQGDFPSEK 1610 Query: 156 K-----QMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSAT 210 + +++ E +K+D P +P+ G S + + K S T+ + Sbjct: 1611 QDVALAELSLEPEKKD--KPHQPLELPNAGSEFSSDLGRQSGSIGTKQAKSPITETEDSV 1668 Query: 211 IPK 213 + K Sbjct: 1669 LEK 1671 Score = 32.7 bits (73), Expect = 1.1 Identities = 55/287 (19%), Positives = 101/287 (35%), Gaps = 22/287 (7%) Query: 8 QDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEG 67 +DL LPPS + + + + A KQ+ + + + E Sbjct: 1076 EDLSLPPSTDKSEKAEIKPEIPTTSTSVSEYLILAQKQKTQAYLEPESEDLIPSHLTSEV 1135 Query: 68 TKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTP 127 K + + PA+S ++V + P P + L +S I K+ T Sbjct: 1136 EKGEREASSSVAAIPAALPAQS---SIVKEETKPASPHSVLPDSVPAIK----KEQEPTA 1188 Query: 128 HLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQK---QDANMPKKPVLGSYRGQIVQ 184 L L D Q + + + ++ + ++ QK Q N+P+ + S +V Sbjct: 1189 ALTLKAADEQMALSKVRKEEIVPDSQEATAHVSQDQKMEPQPPNVPESEMKYSVLPDMVD 1248 Query: 185 SKINSFRKPLQVKDESSAATKKLSATIPKATKPQ----------PVNTSSVTVKSNRSSN 234 + L + S +KLS P+ KP P S+V ++ S Sbjct: 1249 EPKKGVKPKLVLNVTSELEQRKLSKNEPEVIKPYSPLKETSLSGPEALSAVKMEMKHDSK 1308 Query: 235 MTATTKFVSTTSQNT--QLVRPPIRSHHSNTRDTVKQGISRTSANVT 279 +T T + + S Q+ P S + +K+ I +S+ T Sbjct: 1309 ITTTPIVLHSASSGVEKQVEHGPPALAFSALSEEIKKEIEPSSSTTT 1355 >gi|34452686 ring finger protein, LIM domain interacting [Homo sapiens] Length = 624 Score = 40.4 bits (93), Expect = 0.005 Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 10/206 (4%) Query: 165 QDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSA-TIPKATKPQPVNTS 223 Q++ +P G+ V++ NS R+ + ES++A S +A P Sbjct: 150 QNSENENEPSARRSSGENVEN--NSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRG 207 Query: 224 SVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVK-------QGISRTSA 276 +S + + + S + P RSHHS + T + +G SRT Sbjct: 208 QRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRH 267 Query: 277 NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 336 +VT+R+ ELL +S ++SQG + T + ++ RP ++ D + + Sbjct: 268 HVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRR 327 Query: 337 SEPVDQRRHTAGKAIVDSRSAQPKET 362 P + R+ + + SRS P T Sbjct: 328 VRPGEYRQRDSIASRTRSRSQTPNNT 353 >gi|34452684 ring finger protein, LIM domain interacting [Homo sapiens] Length = 624 Score = 40.4 bits (93), Expect = 0.005 Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 10/206 (4%) Query: 165 QDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSA-TIPKATKPQPVNTS 223 Q++ +P G+ V++ NS R+ + ES++A S +A P Sbjct: 150 QNSENENEPSARRSSGENVEN--NSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRG 207 Query: 224 SVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVK-------QGISRTSA 276 +S + + + S + P RSHHS + T + +G SRT Sbjct: 208 QRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRH 267 Query: 277 NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 336 +VT+R+ ELL +S ++SQG + T + ++ RP ++ D + + Sbjct: 268 HVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRR 327 Query: 337 SEPVDQRRHTAGKAIVDSRSAQPKET 362 P + R+ + + SRS P T Sbjct: 328 VRPGEYRQRDSIASRTRSRSQTPNNT 353 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 40.4 bits (93), Expect = 0.005 Identities = 51/201 (25%), Positives = 88/201 (43%), Gaps = 37/201 (18%) Query: 181 QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 240 +I + + S P Q +T+ +S +T P ++ +T+ ++ +S + ATT+ Sbjct: 7862 EISKEDVTSIPGPAQSTISPDISTRTVSWF---STSPVMTESAEITMNTH-TSPLGATTQ 7917 Query: 241 FVST--TSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHE---------KEL 289 ST TS T L T T+ QG S + + +R+GP + ++ Sbjct: 7918 GTSTLDTSSTTSLTM---------THSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKT 7968 Query: 290 LQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSN------DKLMEKSEPVDQR 343 S + +SS T+S + + TL SI+S + + L++ D L + SEPV Sbjct: 7969 RPSFSLMSSPATTSPSPV--SSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPV--- 8023 Query: 344 RHTAGKAIVDSRSAQPKETSE 364 T A + S S + TSE Sbjct: 8024 --TNSPANLSSTSVEILATSE 8042 Score = 37.0 bits (84), Expect = 0.060 Identities = 44/183 (24%), Positives = 73/183 (39%), Gaps = 20/183 (10%) Query: 217 PQPVNTSSVTVKSNRSSNMT---ATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISR 273 P V SVT K+ S +T T +++T + R +S S T ++ IS Sbjct: 9238 PSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISE 9297 Query: 274 TSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKL 333 +++ T + T LSSV T ++ + R + +S S S +++S+D Sbjct: 9298 ETSSAT-----------EKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTS 9346 Query: 334 MEK----SEPVDQRRHT--AGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNS 387 ME S P+ ++ T A A + T + + W +R P S Sbjct: 9347 METITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQS 9406 Query: 388 VVT 390 VVT Sbjct: 9407 VVT 9409 Score = 33.1 bits (74), Expect = 0.87 Identities = 47/205 (22%), Positives = 87/205 (42%), Gaps = 15/205 (7%) Query: 126 TPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKK--PVLGSYRGQIV 183 +P L ++ + H T + N+ + T +++ M P LG + Sbjct: 408 SPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGF---TTL 464 Query: 184 QSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVS 243 SKI R P QV SS T++L T + + Q +T++ + ++T+K S Sbjct: 465 DSKI---RSPSQVS--SSHPTRELRTTGSTSGR-QSSSTAAHGSSDILRATTSSTSKASS 518 Query: 244 TTSQNT-QLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTS 302 TS++T Q P + T ++K S +V P + + +++KTS Sbjct: 519 WTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVA---APITTSVPSVVSGFTTLKTS 575 Query: 303 SSQGIIRNKTLSRSIASEVIARPAS 327 S++GI +T + ++ E A P + Sbjct: 576 STKGIWLEETSADTLIGESTAGPTT 600 Score = 32.3 bits (72), Expect = 1.5 Identities = 41/178 (23%), Positives = 76/178 (42%), Gaps = 18/178 (10%) Query: 198 DESSAATKKLSA---TIPK---ATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQL 251 +E+S+ + +S+ T P +T PQ + +S + V + +S + TT + TTS + Sbjct: 5330 EETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVT 5389 Query: 252 VRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNK 311 PP S ++ R + + T A + H + TA+++V TS S ++ Sbjct: 5390 SSPPNLSSITHERPATYKDTAHTEAAM------HH----STNTAVTNVGTSGSGHKSQSS 5439 Query: 312 TLSRSIASEV--IARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERK 367 L+ S S+ + S D + S P + + S S + +E+S K Sbjct: 5440 VLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEK 5497 Score = 32.3 bits (72), Expect = 1.5 Identities = 46/196 (23%), Positives = 74/196 (37%), Gaps = 31/196 (15%) Query: 123 SNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQI 182 S TP++ T +LS + S+K TTE + +P + + R +I Sbjct: 5465 STSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEI 5524 Query: 183 VQSK--INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 240 S+ I+ +P D S+ +L + P+ T +S+ MT TT+ Sbjct: 5525 SSSRTSISDLDRPTIAPDISTGMITRLFTS--------PIMT--------KSAEMTVTTQ 5568 Query: 241 FVSTTSQNTQLVRPPIRS---HHSNTRDTVKQGI---------SRTSANVTIRKGPHEKE 288 +T +Q + P S T TV QG SRT +V+ P +E Sbjct: 5569 -TTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEE 5627 Query: 289 LLQSKTALSSVKTSSS 304 + +S TS S Sbjct: 5628 TSSGFSLMSPSMTSPS 5643 Score = 31.6 bits (70), Expect = 2.5 Identities = 58/284 (20%), Positives = 108/284 (38%), Gaps = 36/284 (12%) Query: 50 LSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELT 109 L S ++ T+ + +++ K+ T +A +E ++ + V + P K ++ + Sbjct: 6566 LGSTSHKIPTTSEDIKDTEKMYP-STNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMV 6624 Query: 110 NS----TVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQ--MTTEKQ 163 S ++ T P S +T + +S T S A LK S + ++TEK Sbjct: 6625 TSFNIRDTIVSTSMPGSSE------ITRIEMES---TFSLAHGLKGTSTSQDPIVSTEKS 6675 Query: 164 KQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTS 223 + S R ++ S+ S P D S+ + + IP Sbjct: 6676 AVLHKLTTGATETS-RTEVASSRRTSIPGP----DHSTESPDISTEVIPSLP-------- 6722 Query: 224 SVTVKSNRSSNMTATTKF---VSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTI 280 +++ SSNMT T+ + +TSQ T + P S + T Q + + Sbjct: 6723 -ISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVM 6781 Query: 281 RKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIAR 324 K P E+L S KTS S ++ + ++ S + + Sbjct: 6782 NKDP---EILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPK 6822 Score = 31.2 bits (69), Expect = 3.3 Identities = 69/329 (20%), Positives = 125/329 (37%), Gaps = 38/329 (11%) Query: 47 NEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKE-NMKRPAESKNNTVVGKHCIPLKPS 105 +E L++ T V E T ++T A +E P S+ V+ P+ S Sbjct: 9497 DESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVIS----PVVTS 9552 Query: 106 NELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQ 165 + + ++ ++ T P S +T + +S +L+ S+ +TE Sbjct: 9553 SSIRDN--MVSTTMPGSSG------ITRIEIESMS-SLTPGLRETRTSQDITSSTETSTV 9603 Query: 166 DANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSV 225 MP R +++ S S P Q S + +S + P+ T S Sbjct: 9604 LYKMPSGATPEVSRTEVMPSSRTSIPGPAQ-----STMSLDISDEVVTRLSTSPIMTESA 9658 Query: 226 TVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPH 285 + +T T + TSQ T L + S T T+ QG+S + + +GP Sbjct: 9659 EI------TITTQTGYSLATSQVT-LPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPE 9711 Query: 286 E--------KELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKS 337 E +S ++L+S+ ++S + + L S +S + SL L++ + Sbjct: 9712 SLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPV--TSLILPGLVKTT 9769 Query: 338 EPVD--QRRHTAGKAIVDSRSAQPKETSE 364 E +D T+ + S S + TSE Sbjct: 9770 EVLDTSSEPKTSSSPNLSSTSVEIPATSE 9798 Score = 31.2 bits (69), Expect = 3.3 Identities = 38/158 (24%), Positives = 60/158 (37%), Gaps = 19/158 (12%) Query: 181 QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNR---SSNMTA 237 +I S +R + ESS +L T QP TSS + R S + Sbjct: 10350 EITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGT 10409 Query: 238 TTKFVSTTSQNTQLVRP----------PIRSHHSNTRDTVKQGISRTSANVTIRKGPHEK 287 T S +T+L R P + H T VK +TS + KG H Sbjct: 10410 VTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKG--PQTSTSPASPKGLHTG 10467 Query: 288 ELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARP 325 + +T +++KT+++ KT SR+ + + P Sbjct: 10468 GTKRMETTTTALKTTTT----ALKTTSRATLTTSVYTP 10501 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 40.0 bits (92), Expect = 0.007 Identities = 70/334 (20%), Positives = 130/334 (38%), Gaps = 42/334 (12%) Query: 53 RDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNST 112 + Q V +SED E + +E K P ++ VV K P+ + S+ Sbjct: 315 KQQPVESSEDSSDESDS--------SSEEEKKPPTKA----VVSKATTKPPPAKKAAESS 362 Query: 113 VVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQK-QDANMPK 171 DS+ + D + A KN+S K +TT+ + A PK Sbjct: 363 --------SDSSDS-------DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK 407 Query: 172 KPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNR 231 +PV G + ++ K +S + TKK+ AT TKP+ +++++ + + Sbjct: 408 QPVGGGQK--LLTRKADSSSSEEESSSSEEEKTKKMVAT----TKPKATAKAALSLPAKQ 461 Query: 232 SSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQ 291 + + + S +S + + +S V G + S + +KG E Sbjct: 462 APQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG-AAPSKPASAKKGKAE----S 516 Query: 292 SKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPA-SLSNDKLMEKSEPVDQRRHTAGKA 350 S ++ S + + ++ K R A + A + N K + SE ++ + A A Sbjct: 517 SNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKA--A 574 Query: 351 IVDSRSAQPKETSEERKARLSEWKAGKGRVLKRP 384 +V S+S K+ + A+ +E K L+ P Sbjct: 575 VVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTP 608 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 40.0 bits (92), Expect = 0.007 Identities = 77/405 (19%), Positives = 149/405 (36%), Gaps = 47/405 (11%) Query: 10 LQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVT---SEDQVQE 66 LQ PP A R Q HL KT + ++ E S+D++ T + + + Sbjct: 85 LQWPPIYTAA------REQTPFRHLYTSKT---HLKKAEYKKSKDEKGGTPLKKDSKKKG 135 Query: 67 GTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQT 126 G+ ++K +E KR E+ PLK S+E S + + +Q Sbjct: 136 GSYATNPESKQIVEEKTKRQNEADKT--------PLKSSHENEQSKKSKSSSETNPESQN 187 Query: 127 PHLLLT------EDDPQSQHMTLSQAFHLKNNSKK--KQMTTEKQKQDANMPKKPVLGSY 178 + + D ++ T ++ H KNN KK K+ T + + + Sbjct: 188 SKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDF 247 Query: 179 RGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTAT 238 + QS S +++ S +K S K TK K N + A Sbjct: 248 LMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKD--------TKKNAKKSSDAE 299 Query: 239 TKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSS 298 ++ ++++ V+ ++ +D K+ + + + + G + E +K Sbjct: 300 SEDSKDAKKDSKKVKKNVK------KDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKK 353 Query: 299 VKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAI--VDSRS 356 +K + K S +E + ++ + ++K+ D ++ A K DS S Sbjct: 354 LKKDDKKK--DTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSES 411 Query: 357 A-QPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEK 400 + KE+ ++ K + K + +K S EP G ++K Sbjct: 412 ELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKK 456 >gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] Length = 4377 Score = 39.7 bits (91), Expect = 0.009 Identities = 67/309 (21%), Positives = 113/309 (36%), Gaps = 40/309 (12%) Query: 75 TKMADKENMKRPAESKNNTVVGKHCIPLKP--------SNELTN----STVVIDTHKPKD 122 T +K+N + + K V+ HC+ K + EL S + I PKD Sbjct: 3815 TCTTEKDNPVKVSSGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSPKD 3874 Query: 123 SNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQI 182 + H+ T+ Q + + K K +TT + + PV ++R I Sbjct: 3875 TFPPNHMSNTKASKMKQ---------VSQSEKTKALTTSSCVDVKS--RIPVKNTHRDNI 3923 Query: 183 VQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFV 242 + + RK + + K K PV S V + ++ T TT Sbjct: 3924 I-----AVRKACATQKQGQPEKGKAKQLPSKL----PVKVRSTCVTTTTTTATTTTTTTT 3974 Query: 243 STTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTS 302 +TT+ T VR +GIS + + R EK++ ++ LS + S Sbjct: 3975 TTTTSCTVKVRKSQLKEVCKHSIEYFKGISGETLKLVDRLSEEEKKM---QSELSDEEES 4031 Query: 303 SSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKET 362 +S RN +LS + + + DK E + P+ + AG SR P+ Sbjct: 4032 TS----RNTSLSETSRGGQPSVTTKSARDKKTE-AAPLKSKSEKAGSEKRSSRRTGPQSP 4086 Query: 363 SEERKARLS 371 E R++ Sbjct: 4087 CERTDIRMA 4095 >gi|24431975 hypothetical protein LOC26148 [Homo sapiens] Length = 1247 Score = 39.7 bits (91), Expect = 0.009 Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 17/183 (9%) Query: 192 KPLQVKDESSAATKKLSATIPKA---TKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQN 248 KP + K++S +PKA +K + SS N+ + A+ + + + Sbjct: 1061 KPKSTEGMKGRKGKQVSEILPKAEVQSKRKRTEGSSPPDSKNKGPTVKASKEKHADGATK 1120 Query: 249 TQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGII 308 T + P RD Q +TS K + K+A S S + Sbjct: 1121 TPAAKRPA------ARDRSSQPPKKTSLK-------ENKVKIPKKSAGKSCPPSRKEKEN 1167 Query: 309 RNKTLSRSIASEVIARPASLSN-DKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERK 367 NK S+SIASE + +PA + + + R+ ++GK + P+ ++ +RK Sbjct: 1168 TNKRPSQSIASETLTKPAKQKGAGESSSRPQKATNRKQSSGKTRARPSTKTPESSAAQRK 1227 Query: 368 ARL 370 +L Sbjct: 1228 RKL 1230 >gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] Length = 558 Score = 39.3 bits (90), Expect = 0.012 Identities = 64/367 (17%), Positives = 142/367 (38%), Gaps = 28/367 (7%) Query: 16 QRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKT 75 +R + A +E+ RQK +E L + T + + + T+ QV EG Sbjct: 34 ERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV-EGDDEAAFLE 92 Query: 76 KMADKENMKRPA-------ESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPH 128 ++A +E ++ + + + + + L PS + N T +T + ++ +++ Sbjct: 93 RLARREERRQKRLQEALERQKEFDPTITDASLSL-PSRRMQNDTAENETTEKEEKSESRQ 151 Query: 129 LLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKIN 188 ++ ++ + Q ++ + K+ EK++++ PK+ +G +G+ +K+ Sbjct: 152 ERYEIEETETVTKSY-QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQ 210 Query: 189 SFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQN 248 + R+ LQ + + I K +P K S M F SQN Sbjct: 211 AKREKLQEDKPTFKKEEIKDEKIKKDKEP----------KEEVKSFMDRKKGFTEVKSQN 260 Query: 249 TQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKEL---LQSKTALSSVKTSSSQ 305 + + ++ +T +T + R S + +G + E L+ S Sbjct: 261 GEFMTHKLK----HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 316 Query: 306 GIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEE 365 ++ K ++ E + + K++E+ E ++ K + + KE E Sbjct: 317 EKLKQKQQEAALELEELKKKRE-ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIER 375 Query: 366 RKARLSE 372 R+A +E Sbjct: 376 RRAEAAE 382 >gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] Length = 564 Score = 39.3 bits (90), Expect = 0.012 Identities = 64/367 (17%), Positives = 142/367 (38%), Gaps = 28/367 (7%) Query: 16 QRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKT 75 +R + A +E+ RQK +E L + T + + + T+ QV EG Sbjct: 40 ERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV-EGDDEAAFLE 98 Query: 76 KMADKENMKRPA-------ESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPH 128 ++A +E ++ + + + + + L PS + N T +T + ++ +++ Sbjct: 99 RLARREERRQKRLQEALERQKEFDPTITDASLSL-PSRRMQNDTAENETTEKEEKSESRQ 157 Query: 129 LLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKIN 188 ++ ++ + Q ++ + K+ EK++++ PK+ +G +G+ +K+ Sbjct: 158 ERYEIEETETVTKSY-QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQ 216 Query: 189 SFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQN 248 + R+ LQ + + I K +P K S M F SQN Sbjct: 217 AKREKLQEDKPTFKKEEIKDEKIKKDKEP----------KEEVKSFMDRKKGFTEVKSQN 266 Query: 249 TQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKEL---LQSKTALSSVKTSSSQ 305 + + ++ +T +T + R S + +G + E L+ S Sbjct: 267 GEFMTHKLK----HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 322 Query: 306 GIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEE 365 ++ K ++ E + + K++E+ E ++ K + + KE E Sbjct: 323 EKLKQKQQEAALELEELKKKRE-ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIER 381 Query: 366 RKARLSE 372 R+A +E Sbjct: 382 RRAEAAE 388 >gi|45269141 multimerin 1 [Homo sapiens] Length = 1228 Score = 38.9 bits (89), Expect = 0.016 Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 17/189 (8%) Query: 412 EDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEP 471 ED+ R F + S+ +N++ +E + ND+ + + K V +L E Sbjct: 365 EDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVS-----SLSED 419 Query: 472 ITSPIENIIAIYEKAILAGAQP----IEEMRHTIVDILTMKSQEKANLGENMEKSCASKE 527 + S + I + E + AQ ++E R T+ DI+ +++ N+ + M +C ++ Sbjct: 420 LESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRN-HIVNVRQEMTLTC--EK 476 Query: 528 EVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEK-----EQDNKTKDPTHDVKTPNTE 582 +KE+ ++ T ++ E+ S L+ L + K EQ T+ + P E Sbjct: 477 PIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAE 536 Query: 583 TRTSCLIKY 591 + ++ + +Y Sbjct: 537 SVSNNVTEY 545 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 38.9 bits (89), Expect = 0.016 Identities = 79/389 (20%), Positives = 150/389 (38%), Gaps = 52/389 (13%) Query: 14 PSQRAQSAFKEQRRQKLKEHLLRRKTLF---AYKQENEMLSSRDQRVVTSEDQVQEGTKV 70 P +R+ +E++R + R K+ A +++ + + V E VQE T Sbjct: 182 PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241 Query: 71 LKLKTKMADKENMKRPAES--KNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPH 128 + K+ E + P E + N+ K +P + + K ++T Sbjct: 242 SDI-LKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSR----------SRSKSRSRTRS 290 Query: 129 LLLTEDDPQSQHMTLSQAFHLKNN-SKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKI 187 + P+ +H + S+++ + S +++ + ++ MP P R + + + Sbjct: 291 RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR- 349 Query: 188 NSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQ 247 R + SS+++ S + PK KP P TSS K+ R S + + + Sbjct: 350 ---RSSASLSGSSSSSSSSRSRSPPK--KP-PKRTSSPPRKTRRLSPSASPPR---RRHR 400 Query: 248 NTQLVRPPIRSHHSNT--------RDTVKQGISRTSANVTIRKG------------PHEK 287 + PP ++ HS T + V RTS VT KG P + Sbjct: 401 PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460 Query: 288 ELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKS-----EPVDQ 342 EL +S+ ++ R + ++ S + +S S D+ ++S E + Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR 520 Query: 343 RRHTAGKAIVDSRSAQPKETSEERKARLS 371 RRH+ ++ S + KETS + R S Sbjct: 521 RRHSPSRSASPSPRKRQKETSPRGRRRRS 549 >gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens] Length = 1069 Score = 38.1 bits (87), Expect = 0.027 Identities = 67/351 (19%), Positives = 133/351 (37%), Gaps = 36/351 (10%) Query: 6 VPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSS----RDQRVVTSE 61 + + L + Q+ Q + +L+EH+ ++ L A KQ+ E+L QR Sbjct: 59 IQKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQEV 118 Query: 62 DQVQEGTKVLKLKTKMADKENMKRPAESKNNT---VVGKHCIPLKPSNELTNSTVVIDTH 118 ++ + ++ L+ K +E E K ++ K P+N +S + H Sbjct: 119 ERHRREQQLPPLRGKDRGRERAVASTEVKQKLQEFLLSKSATKDTPTNGKNHS---VSRH 175 Query: 119 KPKDSNQTPHLLLTEDDP------QSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKK 172 H L + P S TL A K++ ++ +E + + K+ Sbjct: 176 PKLWYTAAHHTSLDQSSPPLSGTSPSYKYTLPGAQDAKDDFPLRKTASEPNLKVRSRLKQ 235 Query: 173 PVLGSYRGQIVQSK----INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVK 228 V +++ K + SF+K + ESS +S++ P + P N + +V Sbjct: 236 KVAERRSSPLLRRKDGNVVTSFKKRMFEVTESS-----VSSSSPGSGPSSPNNGPTGSVT 290 Query: 229 SNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKE 288 N +S + T SQ L+ H ++ + + S + N+T+ P Sbjct: 291 ENETSVLPPTPHAEQMVSQQRILI-------HEDSMNLLSLYTSPSLPNITLGL-PAVPS 342 Query: 289 LLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEP 339 L + +L + +Q + + L + PAS S+ + + +P Sbjct: 343 QLNASNSLKEKQKCETQTLRQGVPLPGQYGGSI---PASSSHPHVTLEGKP 390 >gi|18379328 WW domain-containing adapter with a coiled-coil region isoform 1 [Homo sapiens] Length = 647 Score = 37.7 bits (86), Expect = 0.035 Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 10/134 (7%) Query: 204 TKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVR-----PPIRS 258 T +S +T+ QP N S +++ S+ SS + + +ST NT ++ PP+ S Sbjct: 417 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 476 Query: 259 HHSNTRDTVKQG---ISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSR 315 + VKQG S T VT K + + SS + S S G N T + Sbjct: 477 QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG--PNHTSNS 534 Query: 316 SIASEVIARPASLS 329 S AS P + S Sbjct: 535 SNASNATVVPQNSS 548 >gi|18379332 WW domain-containing adapter with a coiled-coil region isoform 3 [Homo sapiens] Length = 544 Score = 37.7 bits (86), Expect = 0.035 Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 10/134 (7%) Query: 204 TKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVR-----PPIRS 258 T +S +T+ QP N S +++ S+ SS + + +ST NT ++ PP+ S Sbjct: 314 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 373 Query: 259 HHSNTRDTVKQG---ISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSR 315 + VKQG S T VT K + + SS + S S G N T + Sbjct: 374 QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG--PNHTSNS 431 Query: 316 SIASEVIARPASLS 329 S AS P + S Sbjct: 432 SNASNATVVPQNSS 445 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 37.7 bits (86), Expect = 0.035 Identities = 75/371 (20%), Positives = 135/371 (36%), Gaps = 41/371 (11%) Query: 16 QRAQSAFKEQRRQKLKEHLLR-----RKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKV 70 QR Q+ E R + ++ + R+T EN+ + ++ + + + G + Sbjct: 920 QREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIER 979 Query: 71 LKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLL 130 ++T D + P + + + K K +++++ + K K +TP + Sbjct: 980 GNIETTSEDGQVFS-PKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKK-KRGPRTPPIT 1037 Query: 131 LTEDDPQSQHMTLSQAFHLKN----NSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSK 186 E+ L + + KN +S+KK+ T D ++P + + + Sbjct: 1038 TKEE--------LVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATT 1089 Query: 187 INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTS 246 S PL +AT AT T++ S +S +T +T T + Sbjct: 1090 PGSTPSPLSSLLPPPPPVATATATTVPATLAA---TTAAAATSFSTSAITISTSATPTNT 1146 Query: 247 QNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQG 306 N SH R V++ + +VTI H K + Q K SSS G Sbjct: 1147 TNNTFANED--SHRKCHRTRVEKV---ETPHVTIEDAQHRKPMDQ--------KRSSSLG 1193 Query: 307 IIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEER 366 +RS S R S SND + R+ D + E + ER Sbjct: 1194 S------NRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGER 1247 Query: 367 KARLSEWKAGK 377 K+R+ + K G+ Sbjct: 1248 KSRIDQLKRGE 1258 >gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical region 1 [Homo sapiens] Length = 1400 Score = 37.0 bits (84), Expect = 0.060 Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 9/117 (7%) Query: 197 KDESSAATKKLSATIPK--------ATKPQPVNTSSVTVKSNRSSNMTAT-TKFVSTTSQ 247 K + T +SAT+PK +T NT+S T+ + + T+T T +T Sbjct: 1121 KTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFT 1180 Query: 248 NTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSS 304 T + ++T D+ IS ++ T+ P ++T +SV T++S Sbjct: 1181 TTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTS 1237 >gi|11225260 DNA topoisomerase I [Homo sapiens] Length = 765 Score = 36.6 bits (83), Expect = 0.079 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%) Query: 119 KPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSY 178 K KD ++ H D + +H + H K+ S +K K + ++ V S Sbjct: 40 KEKDREKSKHSNSEHKDSEKKHKEKEKTKH-KDGSSEKHKDKHKDRDKEKRKEEKVRASG 98 Query: 179 RGQIVQSKINSFRKPLQVKDE 199 +I + K N F P Q+KDE Sbjct: 99 DAKIKKEKENGFSSPPQIKDE 119 >gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] Length = 3664 Score = 36.6 bits (83), Expect = 0.079 Identities = 105/575 (18%), Positives = 217/575 (37%), Gaps = 72/575 (12%) Query: 79 DKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQS 138 D+++ +RP E + V + P P + + + P DS + L D Sbjct: 714 DRDHERRPIERSQSPVHLRR--PQSPGASPSQAERL-----PSDSER--RLYSRSSDRSG 764 Query: 139 QHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKD 198 +LS + K + + + T+ +K D P + V+ + RK KD Sbjct: 765 SCSSLSPPRYEKLDKSRLERYTKNEKTDKERTFDP-------ERVERERRLIRKEKVEKD 817 Query: 199 ESSAATKKLSATIP--KATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPI 256 ++ +K P ++++ N + + RS N + K +L P Sbjct: 818 KTDKQKRKGKVHSPSSQSSETDQENEREQSPEKPRSCNKLSREKADKEGIAKNRLELMPC 877 Query: 257 RSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRS 316 TR K+G V K + + ++S ++ S ++ + + S Sbjct: 878 VVL---TRVKEKEGKVIDHTPVEKLKAKLDNDTVKSSALDQKLQVSQTEPAKSDLSKLES 934 Query: 317 IASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAG 376 + +V S+ +++EK + R+H + D SA E E RK R ++ Sbjct: 935 VRMKVPKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGVSAVDLEKLEARKRRFAD---- 990 Query: 377 KGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEG 436 N + +P + P E ++ R+ ++K + S + L+ EG Sbjct: 991 --------SNLKAEKQKPEVKKSSP---------EMEDARVLSKKQPDVSSREVILLREG 1033 Query: 437 CPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEE 496 + + +++K ++KK I L + + SP ++ + ++ +G++P + Sbjct: 1034 --EAERKPVRKEILKR--ESKK-----IKLDRLNTVASP-KDCQELASISVGSGSRPSSD 1083 Query: 497 MRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNL 556 ++ + + + + N +K SK ++K++ + D D PE+ + +N Sbjct: 1084 LQARLGE---LAGESVENQEVQSKKPIPSKPQLKQLQVLD---DQGPER----EDVRKNY 1133 Query: 557 LFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFK 616 E + ++ +H V NTE + I + S ++ ++K Q + K Sbjct: 1134 CSLRDETPERKSGQEKSHSV---NTEEKIGIDIDHTQSYRKQMEQSRRKQQME--MEIAK 1188 Query: 617 ELKFLTPVR-----RSRRLQEKTSKLPDMLKDHYP 646 KF +P + R L + K P + D P Sbjct: 1189 SEKFGSPKKDVDEYERRSLVHEVGKPPQDVTDDSP 1223 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 36.6 bits (83), Expect = 0.079 Identities = 66/300 (22%), Positives = 115/300 (38%), Gaps = 32/300 (10%) Query: 120 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 179 PK S++ P P++ H S +Q ++Q PKKPV S R Sbjct: 564 PKSSSKAPRA-----PPEAPHPGKRSC----QKSPAQQEPPQRQTVGTKQPKKPVKASAR 614 Query: 180 G---QIVQSKINSFRKPLQVKDESSAATKKLSAT-IPKA---TKPQPVNTSSVTVKSNRS 232 +Q + P +D++S K+ P+A +P+P S K ++S Sbjct: 615 AGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKS 674 Query: 233 SNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGI------SRTSA---NVTIRKG 283 S + A +K +S V H + T QG SRTS V +++ Sbjct: 675 S-LPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQED 733 Query: 284 PHEKEL---LQSKTALSSVK-TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEP 339 + L L+ LS ++ T Q ++ TL + S + P S + E +P Sbjct: 734 SRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITL--DLLSRIPQPPGKGSRQRKAEDKQP 791 Query: 340 VDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNE 399 ++H++ K DS S K+ E + K + +K +S + H+ + + + Sbjct: 792 PAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTK 851 >gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens] Length = 1173 Score = 36.6 bits (83), Expect = 0.079 Identities = 50/227 (22%), Positives = 95/227 (41%), Gaps = 30/227 (13%) Query: 19 QSAFKEQRRQKLKEHLLR--RKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTK 76 Q+ F E+R++ + L+ R+++ +E+ + D Q ++ K + LKT Sbjct: 329 QNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPD-----GPHQKEKFIKHIALKTP 383 Query: 77 ---MADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTE 133 + ++ K P++ + + G L PSN + H ++S+Q E Sbjct: 384 GDVLRLEDISKEPSDETDGSSAG-----LAPSNSGNSGH-----HSTRNSDQIQVAGTKE 433 Query: 134 DDPQSQHMTLSQ-------AFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSK 186 Q H+ LSQ A +L+ N T EK+ + + + P GS +V Sbjct: 434 TKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGS---SLVPLN 490 Query: 187 INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSS 233 + P+ KD+ +++K+ S ++TK + + SN SS Sbjct: 491 AKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSS 537 >gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens] Length = 1186 Score = 36.6 bits (83), Expect = 0.079 Identities = 50/227 (22%), Positives = 95/227 (41%), Gaps = 30/227 (13%) Query: 19 QSAFKEQRRQKLKEHLLR--RKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTK 76 Q+ F E+R++ + L+ R+++ +E+ + D Q ++ K + LKT Sbjct: 329 QNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPD-----GPHQKEKFIKHIALKTP 383 Query: 77 ---MADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTE 133 + ++ K P++ + + G L PSN + H ++S+Q E Sbjct: 384 GDVLRLEDISKEPSDETDGSSAG-----LAPSNSGNSGH-----HSTRNSDQIQVAGTKE 433 Query: 134 DDPQSQHMTLSQ-------AFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSK 186 Q H+ LSQ A +L+ N T EK+ + + + P GS +V Sbjct: 434 TKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGS---SLVPLN 490 Query: 187 INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSS 233 + P+ KD+ +++K+ S ++TK + + SN SS Sbjct: 491 AKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSS 537 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.124 0.341 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,077,034 Number of Sequences: 37866 Number of extensions: 1123247 Number of successful extensions: 4593 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 212 Number of HSP's that attempted gapping in prelim test: 4310 Number of HSP's gapped (non-prelim): 498 length of query: 682 length of database: 18,247,518 effective HSP length: 109 effective length of query: 573 effective length of database: 14,120,124 effective search space: 8090831052 effective search space used: 8090831052 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.