Search of human proteins with 148664201

Search of human proteins with 148664201

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo
sapiens]
         (683 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo s...  1345   0.0  
gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo s...  1339   0.0  
gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens]    148   2e-35
gi|87299628 biorientation of chromosomes in cell division 1-like...    44   4e-04
gi|37595553 ring finger protein 111 [Homo sapiens]                     44   6e-04
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    44   6e-04
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 43   0.001
gi|114431248 hypothetical protein LOC205717 [Homo sapiens]             42   0.002
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         41   0.003
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             41   0.004
gi|34452686 ring finger protein, LIM domain interacting [Homo sa...    40   0.005
gi|34452684 ring finger protein, LIM domain interacting [Homo sa...    40   0.005
gi|83367077 mucin 16 [Homo sapiens]                                    40   0.005
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    40   0.007
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         40   0.009
gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]             40   0.009
gi|24431975 hypothetical protein LOC26148 [Homo sapiens]               40   0.009
gi|45269141 multimerin 1 [Homo sapiens]                                39   0.016
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    39   0.021
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]                       39   0.021
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       39   0.021
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        39   0.021
gi|65507253 hypothetical protein LOC55196 [Homo sapiens]               39   0.021
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    38   0.027
gi|18379328 WW domain-containing adapter with a coiled-coil regi...    38   0.035
gi|18379332 WW domain-containing adapter with a coiled-coil regi...    38   0.035
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    37   0.060
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    37   0.060
gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens]    37   0.060
gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens]    37   0.060

>gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 683

 Score = 1345 bits (3482), Expect = 0.0
 Identities = 683/683 (100%), Positives = 683/683 (100%)

Query: 1   MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVT 60
           MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVT
Sbjct: 1   MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVT 60

Query: 61  SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 120
           SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK
Sbjct: 61  SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 120

Query: 121 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 180
           PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR
Sbjct: 121 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 180

Query: 181 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT 240
           GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT
Sbjct: 181 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT 240

Query: 241 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV 300
           KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV
Sbjct: 241 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV 300

Query: 301 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP 360
           KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP
Sbjct: 301 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP 360

Query: 361 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT 420
           KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT
Sbjct: 361 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT 420

Query: 421 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI 480
           EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI
Sbjct: 421 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI 480

Query: 481 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV 540
           IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV
Sbjct: 481 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV 540

Query: 541 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL 600
           DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL
Sbjct: 541 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL 600

Query: 601 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR 660
           QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR
Sbjct: 601 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR 660

Query: 661 ETDAFVCRPNAALCRVYYEADTT 683
           ETDAFVCRPNAALCRVYYEADTT
Sbjct: 661 ETDAFVCRPNAALCRVYYEADTT 683


>gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 682

 Score = 1339 bits (3466), Expect = 0.0
 Identities = 682/683 (99%), Positives = 682/683 (99%), Gaps = 1/683 (0%)

Query: 1   MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVT 60
           MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSS RDQRVVT
Sbjct: 1   MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSS-RDQRVVT 59

Query: 61  SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 120
           SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK
Sbjct: 60  SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 119

Query: 121 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 180
           PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR
Sbjct: 120 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 179

Query: 181 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT 240
           GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT
Sbjct: 180 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT 239

Query: 241 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV 300
           KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV
Sbjct: 240 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV 299

Query: 301 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP 360
           KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP
Sbjct: 300 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP 359

Query: 361 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT 420
           KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT
Sbjct: 360 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT 419

Query: 421 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI 480
           EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI
Sbjct: 420 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI 479

Query: 481 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV 540
           IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV
Sbjct: 480 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV 539

Query: 541 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL 600
           DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL
Sbjct: 540 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL 599

Query: 601 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR 660
           QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR
Sbjct: 600 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR 659

Query: 661 ETDAFVCRPNAALCRVYYEADTT 683
           ETDAFVCRPNAALCRVYYEADTT
Sbjct: 660 ETDAFVCRPNAALCRVYYEADTT 682


>gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens]
          Length = 745

 Score =  148 bits (373), Expect = 2e-35
 Identities = 130/504 (25%), Positives = 226/504 (44%), Gaps = 72/504 (14%)

Query: 186 SKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVST 245
           SK+ S +KP+ VK+       +     P  TK +    +   VK  +     +       
Sbjct: 287 SKVQSSKKPV-VKNIKDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPS------- 338

Query: 246 TSQNTQLVRPPIRSHHSNTRDTVKQG---ISRTSANVTIRKGPHEKELL---QSKTALSS 299
                 L++    + H N +   K     I +TS  +   K   ++  L   +  +A+ S
Sbjct: 339 ------LLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQKSKAISQRPNLTVGRFNSAIPS 392

Query: 300 VKTSSSQGIIRNKTLSRSIASEVIARPASLSN----DKLMEKSEPVDQRRHTAGKAIVDS 355
             +    G   NK  +     +     + L      +  + K+ P  Q   T       +
Sbjct: 393 TPSIRPNGTSGNKHNNNGFQQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTN 452

Query: 356 RSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDE 415
            + + K T+E+R+ +L EW+  KG+  KRPP  + T+ +   +      SFW ++ +E+E
Sbjct: 453 PNIKKKATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNI---SFWKSIEKEEE 509

Query: 416 QRL----FTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIE 471
           ++      + K+NNT +ECLNLI  G P  +IL    +++ +IP+A+K  K+WIC A + 
Sbjct: 510 EKKAQLELSSKINNTLTECLNLIEGGVPSNEIL----NILSSIPEAEKFAKFWICKAKLL 565

Query: 472 PITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVK 531
                 + +I +YE+AI  GA PI+E+R  +++IL   ++    +         S   V 
Sbjct: 566 ASKGTFD-VIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGI--------TSDSLVA 616

Query: 532 EVSIEDTGVDVDPEKLEMESKLHRNLLFQDC--EKEQDNKTKDPTHDVKTPNTETRTSCL 589
           E SI  T V+   +K+E           + C   KE++  T  P    +    E      
Sbjct: 617 ETSI--TSVEELAKKMES---------VKSCLSPKEREQVTATP----RIAKAEQHNYPG 661

Query: 590 IKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCV 649
           IK  +   P +  + +           +++KF+TPVRRS R++   S+ P+ML++H   V
Sbjct: 662 IKLQIGPIPRINGMPE----------VQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVV 711

Query: 650 SSLEQLTELGRETDAFVCRPNAAL 673
           +SL++L E+  ET  F+ R N AL
Sbjct: 712 ASLDELLEV-EETKCFIFRRNEAL 734


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 94/484 (19%), Positives = 170/484 (35%), Gaps = 111/484 (22%)

Query: 9   DLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEG 68
           D +L   QR QS  KE+  + L+  + R K     KQ+ E   SS+ +    S   ++E 
Sbjct: 485 DDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEES 544

Query: 69  T------------------KVLKLKTKMADK---------ENMKR----PAESKNNTVVG 97
           +                  KVL+ K  ++ K         EN K+      +SK      
Sbjct: 545 STKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTS 604

Query: 98  KHC------------------IPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTE----- 134
           +HC                   P KP+  L+ S  V+D +K +   +  H   T      
Sbjct: 605 EHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIM 664

Query: 135 -----------------------DDPQSQHMTLSQAFHLKNNSK---------KKQMTTE 162
                                  ++PQ Q  TL    HLK +           KK++ + 
Sbjct: 665 EGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSS 724

Query: 163 KQKQD----ANMPKKPVLGSYRGQIV-----QSKINSFRKPLQVKD--ESSAATKKLSAT 211
           K+K +     +  K  V   Y+G  +     +++++S  K L+V++  +  +   KLS+ 
Sbjct: 725 KEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSD 784

Query: 212 IPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQG 271
                K +  N   ++V           ++++  T +N +      +    +   T  + 
Sbjct: 785 DKTERKSKHRNERKLSVLGKDGK---PVSEYIIKTDENVRKENNK-KERRLSAEKTKAEH 840

Query: 272 ISRTSANVTIRKG-----PHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARP 326
            SR S++  I+K       H   L +   + S  K       + +      +  +   R 
Sbjct: 841 KSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRT 900

Query: 327 ASLSNDKLMEKSEPVDQRR-----HTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRV 381
            SL  +KL+ KS+   Q +      T  +     ++  PK   E+        K  K +V
Sbjct: 901 KSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKV 960

Query: 382 LKRP 385
             +P
Sbjct: 961 EDKP 964


>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 58/303 (19%), Positives = 110/303 (36%), Gaps = 26/303 (8%)

Query: 11  QLPPSQRAQSAFKEQRRQKLKEHLL----RRKTLFAYKQENEMLSSSRDQRVVTSEDQVQ 66
           +LP  +R       QR QK KE +L    +R+ L   K      SSS  +  ++SE    
Sbjct: 209 RLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSS 268

Query: 67  EGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQ 126
             T+         +++     +E+  N        P  PS  +    VVI+         
Sbjct: 269 SSTE--------GEEDLFVSASENHQNN-------PAVPSGSIDEDVVVIEASSTPQVTA 313

Query: 127 TPHLLLTEDDPQSQHMTLSQAFHLKNN-SKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQ 185
              + +T  D + + +T+ +++  ++     +   ++     A+ P++P   S    ++Q
Sbjct: 314 NEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQ 373

Query: 186 SKINSFRK--PLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFV 243
               +  +   L V ++        SA +        +N S+ +     S   +A T   
Sbjct: 374 PLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQ 433

Query: 244 STTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTS 303
            +T   T        + +S T  ++     RT+++     GP     L S     S    
Sbjct: 434 PSTVSETSAT----LTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGG 489

Query: 304 SSQ 306
           SSQ
Sbjct: 490 SSQ 492


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 14/164 (8%)

Query: 60  TSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTH 119
           T E Q Q   KV     +    E+  R +ESK      K+    KPS+   +S       
Sbjct: 749 TREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQ--SAA 806

Query: 120 KPKDSNQTPHLLLTEDDPQSQH----MTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPV 175
           K KD   +P   +   DP+++H     T+SQ+  LK++S   + T+   K  ++  K+  
Sbjct: 807 KEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQ-- 864

Query: 176 LGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQ 219
                 +  + K +S  K ++ K  SS++    SA    ++KP+
Sbjct: 865 ------KKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 52/253 (20%), Positives = 99/253 (39%), Gaps = 28/253 (11%)

Query: 12  LPPSQRAQSAFKEQRRQKLK------EHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQV 65
           LPPS +    + E  R  +K      E    R+ +F+  +E E+LS   +      +D+ 
Sbjct: 659 LPPSSQTPK-YPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEP-----DDRY 712

Query: 66  QEGTKV-LKLKTKMADKENMK-RPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKD 123
               K+ L L T++  K   +  P + +   V  KH    +       S      HK +D
Sbjct: 713 PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNED 772

Query: 124 SNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQI 183
            N+          P+++          KN++  K  +  +  + +   +K +L S  G  
Sbjct: 773 DNRASE----SKKPKTED---------KNSAGHKPSSNRESSKQSAAKEKDLLPSPAGP- 818

Query: 184 VQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFV 243
           V SK        + +  S +++ K S+   K T     N+SS + +       ++++K V
Sbjct: 819 VPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV 878

Query: 244 STTSQNTQLVRPP 256
              + ++    PP
Sbjct: 879 KEKAPSSSSNCPP 891


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 77/394 (19%), Positives = 161/394 (40%), Gaps = 46/394 (11%)

Query: 14   PSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLK 73
            P + ++ +  +    +LK+ +    +L   ++E ++ S S  ++    +D ++  +  L 
Sbjct: 2413 PVEESKGSLIDFSEDRLKKEMQNPTSLKISEEETKLRSVSPTEK----KDNLENRSYTLA 2468

Query: 74   LKTKMADKENMKRPAESKNNTVVGKHCIPL-KPSNELTNS---TVVIDTHKPKDSNQTPH 129
             K  +A+K+N   P E +++  +GK  I L   S EL  S    +    ++ +D N+ P 
Sbjct: 2469 EKKVLAEKQNSVAPLELRDSNEIGKTQITLGSRSTELKESKADAMPQHFYQNEDYNERPK 2528

Query: 130  LLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKIN 189
            +++  +  + +    +Q + L    K+++          +M ++  + S    + +++  
Sbjct: 2529 IIVGSEKEKGEEKE-NQVYVLSEGKKQQEHQPYSVNVAESMSRESDI-SLGHSLGETQSF 2586

Query: 190  SFRKPLQVKDESSAATKKLSATIPKA----TKPQPVNTSSVTVKSNRSSNMTATT----- 240
            S  K   V ++S A   +    I +A    T+P P+  S V V+  ++    A +     
Sbjct: 2587 SLVKATSVTEKSEAMLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLPVALSCRDEI 2646

Query: 241  KFVSTTSQNTQLVRPPIRS--HHSN------------------TRDTVKQGISRTSANVT 280
            +  S + +   ++    R    HS                   T++TVKQG    +    
Sbjct: 2647 ENHSLSQEGNLVLEKSSRDMPDHSEEKEQFRESELSKGGSVDITKETVKQGFQEKAVGTQ 2706

Query: 281  IRKGPHEKELLQ-SKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSE 339
             R     K L++ +KT L  V +   +  I N +LS+   + V+ + +    D   EK +
Sbjct: 2707 PRPLEESKVLVEKTKTFLPVVLSCHDE--IENHSLSQE-GNLVLEKSSRDMPDHSEEKEQ 2763

Query: 340  PVDQRRHTAGKAIVDSRSAQ---PKETSEERKAR 370
              +      G   +   S +   P + SE   AR
Sbjct: 2764 FKESELWKGGSVDITKESMKEGFPSKESERTLAR 2797



 Score = 33.9 bits (76), Expect = 0.51
 Identities = 56/290 (19%), Positives = 105/290 (36%), Gaps = 27/290 (9%)

Query: 8    QDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSE--DQV 65
            +DL LPPS       + +         +    + A KQ+ +       + ++ S    +V
Sbjct: 1076 EDLSLPPSTDKSEKAEIKPEIPTTSTSVSEYLILAQKQKTQAYLEPESEDLIPSHLTSEV 1135

Query: 66   QEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSN 125
            ++G +                PA+S   ++V +   P  P + L +S   I     K+  
Sbjct: 1136 EKGEREASSSVAAIPAA---LPAQS---SIVKEETKPASPHSVLPDSVPAIK----KEQE 1185

Query: 126  QTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQK---QDANMPKKPVLGSYRGQ 182
             T  L L   D Q     + +   + ++ +     ++ QK   Q  N+P+  +  S    
Sbjct: 1186 PTAALTLKAADEQMALSKVRKEEIVPDSQEATAHVSQDQKMEPQPPNVPESEMKYSVLPD 1245

Query: 183  IVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQ----------PVNTSSVTVKSNR 232
            +V       +  L +   S    +KLS   P+  KP           P   S+V ++   
Sbjct: 1246 MVDEPKKGVKPKLVLNVTSELEQRKLSKNEPEVIKPYSPLKETSLSGPEALSAVKMEMKH 1305

Query: 233  SSNMTATTKFVSTTSQNT--QLVRPPIRSHHSNTRDTVKQGISRTSANVT 280
             S +T T   + + S     Q+   P     S   + +K+ I  +S+  T
Sbjct: 1306 DSKITTTPIVLHSASSGVEKQVEHGPPALAFSALSEEIKKEIEPSSSTTT 1355


>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
          Length = 2245

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 67/303 (22%), Positives = 111/303 (36%), Gaps = 34/303 (11%)

Query: 94  TVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNN 153
           T  GKH + + P     +++    T     SNQ P  +       +    +S +      
Sbjct: 627 TFGGKHLVHILPRPSSLSASNSTQTFSVTMSNQQPQTISLNGQLFALQPVMSSSGTTNQT 686

Query: 154 SKKKQMTTEKQKQDANMPKKP--VLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSAT 211
             +    T  +  + N+       L S    I Q    S  + L +   +++ T   S T
Sbjct: 687 PMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQ-LSISQPANSQTAANSQT 745

Query: 212 IPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSN-------- 263
              A       T++  V ++ S+ + +T   VST+S NT    P ++S   N        
Sbjct: 746 TT-ANCVSLTTTAAPPVTTDSSATLASTYNLVSTSSMNTVACLPNMKSKRLNKKPGGRKH 804

Query: 264 ------------TRDTVKQGISRTSANVTIRKGPHEKELLQSKTA-LSSVKTSSSQGIIR 310
                        RD  K     T  +    + P    LL+S  A L SV  S +  +  
Sbjct: 805 LAANKSACPLNSVRDVSKLDCPNTEGSA---EPPCNDGLLESFPAVLPSVSVSQANSVSV 861

Query: 311 NKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTA---GKAIVDSRSAQP---KETS 364
           + + S  + S     P S+S  K  EKS P  Q   T+     A   S+ + P   +ETS
Sbjct: 862 SASHSLGVLSSESLIPESVSKSKSAEKSSPPSQESVTSEHFAMAAAKSKDSTPNLQQETS 921

Query: 365 EER 367
           +++
Sbjct: 922 QDK 924


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 78/389 (20%), Positives = 149/389 (38%), Gaps = 51/389 (13%)

Query: 14  PSQRAQSAFKEQRRQKLKE--HLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKV 71
           P +R+    +E++R   +   H  + ++     ++ E      +  V   E  VQE T  
Sbjct: 182 PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241

Query: 72  LKLKTKMADKENMKRPAES--KNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPH 129
             +  K+   E +  P E   + N+   K     +P +            + K  ++T  
Sbjct: 242 SDI-LKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSR----------SRSKSRSRTRS 290

Query: 130 LLLTEDDPQSQHMTLSQAFHLKNN-SKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKI 188
              +   P+ +H + S+++  +   S +++ +  ++     MP  P     R  + + + 
Sbjct: 291 RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR- 349

Query: 189 NSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQ 248
              R    +   SS+++   S + PK  KP P  TSS   K+ R S   +  +      +
Sbjct: 350 ---RSSASLSGSSSSSSSSRSRSPPK--KP-PKRTSSPPRKTRRLSPSASPPR---RRHR 400

Query: 249 NTQLVRPPIRSHHSNT--------RDTVKQGISRTSANVTIRKG------------PHEK 288
            +    PP ++ HS T        +  V     RTS  VT  KG            P + 
Sbjct: 401 PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460

Query: 289 ELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKS-----EPVDQ 343
           EL +S+        ++     R +   ++  S   +  +S S D+  ++S     E   +
Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR 520

Query: 344 RRHTAGKAIVDSRSAQPKETSEERKARLS 372
           RRH+  ++   S   + KETS   + R S
Sbjct: 521 RRHSPSRSASPSPRKRQKETSPRGRRRRS 549


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 110/579 (18%), Positives = 232/579 (40%), Gaps = 67/579 (11%)

Query: 8    QDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQEN----EMLSSSRDQRVVTSED 63
            Q  QL    + QS   +Q ++ L + +  +K      Q+     E   +  + ++  S++
Sbjct: 576  QVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKE 635

Query: 64   QVQEGTKVLKLKTKM---ADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 120
            +V +    +K KT++   A+     + A+ +N+    ++ +  K   EL   T  +D   
Sbjct: 636  KVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDK-QQELNKITTQLDQVT 694

Query: 121  PKDSNQTPHLLLTED---DPQSQHMTLSQ-------------AFHLKNNSKKKQMTTEKQ 164
             K  ++  H    E    + + ++++L Q             A  L+  + K+Q   + Q
Sbjct: 695  AKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQ 754

Query: 165  KQ---DANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDES--SAATKKLSATIPKATKPQ 219
            +Q   + ++  +    S + ++ +  ++S R  LQ K E+  S   K       K    Q
Sbjct: 755  QQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQ 814

Query: 220  PVNTSSVTVKSNRS--SNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSA 277
               T S   K      +N   TT    T  Q  ++ +  + +  S    TVK  +S+ S 
Sbjct: 815  DFETLSQETKIQHEELNNRIQTTV---TELQKVKMEKEALMTELS----TVKDKLSKVSD 867

Query: 278  NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 337
            ++   K   EKE  + K A+  ++ +  +   + +    +   E      SL  +K  E 
Sbjct: 868  SLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEK--EA 925

Query: 338  SEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAG 397
            S  +    ++  + ++ +++   +   EE++ +      G    LK+       Q E A 
Sbjct: 926  SHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQ------GNINELKQSSEQKKKQIE-AL 978

Query: 398  QNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDA 457
            Q E  +     T  E   Q+  T+      +E          KE I V  N+  K+    
Sbjct: 979  QGELKIAVLQKTELENKLQQQLTQAAQELAAE----------KEKISVLQNNYEKSQETF 1028

Query: 458  KKLVKYWI-----CLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKS-- 510
            K+L   +       LA  + + S +E  +++ ++ +++    I      I ++ T K+  
Sbjct: 1029 KQLQSDFYGRESELLATRQDLKS-VEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATL 1087

Query: 511  -QEKANLGENMEKSCASKEEV-KEVSIEDTGVDVDPEKL 547
             Q+ A   + +++ C + +++ KE S+++  +  +  KL
Sbjct: 1088 EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKL 1126


>gi|34452686 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 10/206 (4%)

Query: 166 QDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSA-TIPKATKPQPVNTS 224
           Q++    +P      G+ V++  NS R+    + ES++A    S     +A    P    
Sbjct: 150 QNSENENEPSARRSSGENVEN--NSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRG 207

Query: 225 SVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVK-------QGISRTSA 277
               +S    +     +   + S    +   P RSHHS +  T +       +G SRT  
Sbjct: 208 QRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRH 267

Query: 278 NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 337
           +VT+R+     ELL      +S   ++SQG   + T +   ++    RP ++  D  + +
Sbjct: 268 HVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRR 327

Query: 338 SEPVDQRRHTAGKAIVDSRSAQPKET 363
             P + R+  +  +   SRS  P  T
Sbjct: 328 VRPGEYRQRDSIASRTRSRSQTPNNT 353


>gi|34452684 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 10/206 (4%)

Query: 166 QDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSA-TIPKATKPQPVNTS 224
           Q++    +P      G+ V++  NS R+    + ES++A    S     +A    P    
Sbjct: 150 QNSENENEPSARRSSGENVEN--NSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRG 207

Query: 225 SVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVK-------QGISRTSA 277
               +S    +     +   + S    +   P RSHHS +  T +       +G SRT  
Sbjct: 208 QRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRH 267

Query: 278 NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 337
           +VT+R+     ELL      +S   ++SQG   + T +   ++    RP ++  D  + +
Sbjct: 268 HVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRR 327

Query: 338 SEPVDQRRHTAGKAIVDSRSAQPKET 363
             P + R+  +  +   SRS  P  T
Sbjct: 328 VRPGEYRQRDSIASRTRSRSQTPNNT 353


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 51/201 (25%), Positives = 88/201 (43%), Gaps = 37/201 (18%)

Query: 182  QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 241
            +I +  + S   P Q       +T+ +S     +T P    ++ +T+ ++ +S + ATT+
Sbjct: 7862 EISKEDVTSIPGPAQSTISPDISTRTVSWF---STSPVMTESAEITMNTH-TSPLGATTQ 7917

Query: 242  FVST--TSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHE---------KEL 290
              ST  TS  T L           T  T+ QG S +  +  +R+GP +         ++ 
Sbjct: 7918 GTSTLDTSSTTSLTM---------THSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKT 7968

Query: 291  LQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSN------DKLMEKSEPVDQR 344
              S + +SS  T+S   +  + TL  SI+S  +   + L++      D L + SEPV   
Sbjct: 7969 RPSFSLMSSPATTSPSPV--SSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPV--- 8023

Query: 345  RHTAGKAIVDSRSAQPKETSE 365
              T   A + S S +   TSE
Sbjct: 8024 --TNSPANLSSTSVEILATSE 8042



 Score = 37.0 bits (84), Expect = 0.060
 Identities = 44/183 (24%), Positives = 73/183 (39%), Gaps = 20/183 (10%)

Query: 218  PQPVNTSSVTVKSNRSSNMT---ATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISR 274
            P  V   SVT K+  S  +T     T  +++T   +   R   +S  S T   ++  IS 
Sbjct: 9238 PSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISE 9297

Query: 275  TSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKL 334
             +++ T           +  T LSSV T ++  + R + +S S  S      +++S+D  
Sbjct: 9298 ETSSAT-----------EKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTS 9346

Query: 335  MEK----SEPVDQRRHT--AGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNS 388
            ME     S P+ ++  T  A         A  + T     +  + W        +R P S
Sbjct: 9347 METITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQS 9406

Query: 389  VVT 391
            VVT
Sbjct: 9407 VVT 9409



 Score = 33.1 bits (74), Expect = 0.87
 Identities = 47/205 (22%), Positives = 87/205 (42%), Gaps = 15/205 (7%)

Query: 127 TPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKK--PVLGSYRGQIV 184
           +P   L  ++  + H T  +      N+    + T    +++ M     P LG      +
Sbjct: 408 SPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGF---TTL 464

Query: 185 QSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVS 244
            SKI   R P QV   SS  T++L  T   + + Q  +T++        +  ++T+K  S
Sbjct: 465 DSKI---RSPSQVS--SSHPTRELRTTGSTSGR-QSSSTAAHGSSDILRATTSSTSKASS 518

Query: 245 TTSQNT-QLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTS 303
            TS++T Q    P  +    T  ++K      S +V     P    +    +  +++KTS
Sbjct: 519 WTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVA---APITTSVPSVVSGFTTLKTS 575

Query: 304 SSQGIIRNKTLSRSIASEVIARPAS 328
           S++GI   +T + ++  E  A P +
Sbjct: 576 STKGIWLEETSADTLIGESTAGPTT 600



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 41/178 (23%), Positives = 76/178 (42%), Gaps = 18/178 (10%)

Query: 199  DESSAATKKLSA---TIPK---ATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQL 252
            +E+S+ +  +S+   T P    +T PQ + +S + V +  +S +  TT  + TTS  +  
Sbjct: 5330 EETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVT 5389

Query: 253  VRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNK 312
              PP  S  ++ R    +  + T A +      H      + TA+++V TS S    ++ 
Sbjct: 5390 SSPPNLSSITHERPATYKDTAHTEAAM------HH----STNTAVTNVGTSGSGHKSQSS 5439

Query: 313  TLSRSIASEV--IARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERK 368
             L+ S  S+   +    S   D  +  S P   + +        S S + +E+S   K
Sbjct: 5440 VLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEK 5497



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 46/196 (23%), Positives = 74/196 (37%), Gaps = 31/196 (15%)

Query: 124  SNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQI 183
            S  TP++  T         +LS      + S+K   TTE     + +P   +  + R +I
Sbjct: 5465 STSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEI 5524

Query: 184  VQSK--INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 241
              S+  I+   +P    D S+    +L  +        P+ T        +S+ MT TT+
Sbjct: 5525 SSSRTSISDLDRPTIAPDISTGMITRLFTS--------PIMT--------KSAEMTVTTQ 5568

Query: 242  FVSTTSQNTQLVRPPIRS---HHSNTRDTVKQGI---------SRTSANVTIRKGPHEKE 289
              +T    +Q + P   S       T  TV QG          SRT  +V+    P  +E
Sbjct: 5569 -TTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEE 5627

Query: 290  LLQSKTALSSVKTSSS 305
                 + +S   TS S
Sbjct: 5628 TSSGFSLMSPSMTSPS 5643



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 38/158 (24%), Positives = 60/158 (37%), Gaps = 19/158 (12%)

Query: 182   QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNR---SSNMTA 238
             +I  S    +R    +  ESS    +L       T  QP  TSS  +   R   S  +  
Sbjct: 10350 EITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGT 10409

Query: 239   TTKFVSTTSQNTQLVRP----------PIRSHHSNTRDTVKQGISRTSANVTIRKGPHEK 288
              T      S +T+L R           P  + H  T   VK    +TS +    KG H  
Sbjct: 10410 VTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKG--PQTSTSPASPKGLHTG 10467

Query: 289   ELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARP 326
                + +T  +++KT+++      KT SR+  +  +  P
Sbjct: 10468 GTKRMETTTTALKTTTT----ALKTTSRATLTTSVYTP 10501



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 57/282 (20%), Positives = 107/282 (37%), Gaps = 36/282 (12%)

Query: 53   SRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNS 112
            S   ++ T+ + +++  K+    T +A        +E ++ + V  +  P K ++ +  S
Sbjct: 6568 STSHKIPTTSEDIKDTEKMYP-STNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTS 6626

Query: 113  ----TVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQ--MTTEKQKQ 166
                  ++ T  P  S       +T  + +S   T S A  LK  S  +   ++TEK   
Sbjct: 6627 FNIRDTIVSTSMPGSSE------ITRIEMES---TFSLAHGLKGTSTSQDPIVSTEKSAV 6677

Query: 167  DANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSV 226
               +       S R ++  S+  S   P    D S+ +    +  IP            +
Sbjct: 6678 LHKLTTGATETS-RTEVASSRRTSIPGP----DHSTESPDISTEVIPSLP---------I 6723

Query: 227  TVKSNRSSNMTATTKF---VSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRK 283
            ++    SSNMT  T+    + +TSQ T  +  P  S  + T     Q    +     + K
Sbjct: 6724 SLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNK 6783

Query: 284  GPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIAR 325
             P   E+L      S  KTS S  ++ +  ++    S  + +
Sbjct: 6784 DP---EILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPK 6822



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 48/216 (22%), Positives = 83/216 (38%), Gaps = 24/216 (11%)

Query: 160  TTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQ 219
            +TE       MP        R +++ S   S   P Q     S  +  +S  +       
Sbjct: 9597 STETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQ-----STMSLDISDEVVTRLSTS 9651

Query: 220  PVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANV 279
            P+ T S  +       +T  T +   TSQ T L      +  S T  T+ QG+S +    
Sbjct: 9652 PIMTESAEI------TITTQTGYSLATSQVT-LPLGTSMTFLSGTHSTMSQGLSHSEMTN 9704

Query: 280  TIRKGPHE--------KELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSN 331
             + +GP           E  +S ++L+S+  ++S   + +  L  S +S +     SL  
Sbjct: 9705 LMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPV--TSLIL 9762

Query: 332  DKLMEKSEPVD--QRRHTAGKAIVDSRSAQPKETSE 365
              L++ +E +D      T+    + S S +   TSE
Sbjct: 9763 PGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSE 9798


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 70/334 (20%), Positives = 130/334 (38%), Gaps = 42/334 (12%)

Query: 54  RDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNST 113
           + Q V +SED   E           + +E  K P ++    VV K      P+ +   S+
Sbjct: 315 KQQPVESSEDSSDESDS--------SSEEEKKPPTKA----VVSKATTKPPPAKKAAESS 362

Query: 114 VVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQK-QDANMPK 172
                    DS+ +       D  +        A   KN+S K  +TT+    + A  PK
Sbjct: 363 --------SDSSDS-------DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK 407

Query: 173 KPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNR 232
           +PV G  +  ++  K +S     +        TKK+ AT    TKP+    +++++ + +
Sbjct: 408 QPVGGGQK--LLTRKADSSSSEEESSSSEEEKTKKMVAT----TKPKATAKAALSLPAKQ 461

Query: 233 SSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQ 292
           +   +  +   S +S + +      +S        V  G +  S   + +KG  E     
Sbjct: 462 APQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG-AAPSKPASAKKGKAE----S 516

Query: 293 SKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPA-SLSNDKLMEKSEPVDQRRHTAGKA 351
           S ++ S   +   +  ++ K   R  A +     A +  N K  + SE  ++ +  A  A
Sbjct: 517 SNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKA--A 574

Query: 352 IVDSRSAQPKETSEERKARLSEWKAGKGRVLKRP 385
           +V S+S   K+  +   A+ +E    K   L+ P
Sbjct: 575 VVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTP 608


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 67/309 (21%), Positives = 113/309 (36%), Gaps = 40/309 (12%)

Query: 76   TKMADKENMKRPAESKNNTVVGKHCIPLKP--------SNELTN----STVVIDTHKPKD 123
            T   +K+N  + +  K   V+  HC+  K         + EL      S + I    PKD
Sbjct: 3815 TCTTEKDNPVKVSSGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSPKD 3874

Query: 124  SNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQI 183
            +    H+  T+     Q         +  + K K +TT       +  + PV  ++R  I
Sbjct: 3875 TFPPNHMSNTKASKMKQ---------VSQSEKTKALTTSSCVDVKS--RIPVKNTHRDNI 3923

Query: 184  VQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFV 243
            +     + RK    + +      K      K     PV   S  V +  ++  T TT   
Sbjct: 3924 I-----AVRKACATQKQGQPEKGKAKQLPSKL----PVKVRSTCVTTTTTTATTTTTTTT 3974

Query: 244  STTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTS 303
            +TT+  T  VR               +GIS  +  +  R    EK++   ++ LS  + S
Sbjct: 3975 TTTTSCTVKVRKSQLKEVCKHSIEYFKGISGETLKLVDRLSEEEKKM---QSELSDEEES 4031

Query: 304  SSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKET 363
            +S    RN +LS +      +     + DK  E + P+  +   AG     SR   P+  
Sbjct: 4032 TS----RNTSLSETSRGGQPSVTTKSARDKKTE-AAPLKSKSEKAGSEKRSSRRTGPQSP 4086

Query: 364  SEERKARLS 372
             E    R++
Sbjct: 4087 CERTDIRMA 4095


>gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]
          Length = 1069

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 67/351 (19%), Positives = 133/351 (37%), Gaps = 35/351 (9%)

Query: 6   VPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQV 65
           + + L +   Q+       Q + +L+EH+  ++ L A KQ+ E+L   +       E +V
Sbjct: 59  IQKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQEV 118

Query: 66  QEGTK---VLKLKTKMADKENMKRPAESKNNT---VVGKHCIPLKPSNELTNSTVVIDTH 119
           +   +   +  L+ K   +E      E K      ++ K      P+N   +S   +  H
Sbjct: 119 ERHRREQQLPPLRGKDRGRERAVASTEVKQKLQEFLLSKSATKDTPTNGKNHS---VSRH 175

Query: 120 KPKDSNQTPHLLLTEDDP------QSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKK 173
                    H  L +  P       S   TL  A   K++   ++  +E   +  +  K+
Sbjct: 176 PKLWYTAAHHTSLDQSSPPLSGTSPSYKYTLPGAQDAKDDFPLRKTASEPNLKVRSRLKQ 235

Query: 174 PVLGSYRGQIVQSK----INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVK 229
            V       +++ K    + SF+K +    ESS     +S++ P +    P N  + +V 
Sbjct: 236 KVAERRSSPLLRRKDGNVVTSFKKRMFEVTESS-----VSSSSPGSGPSSPNNGPTGSVT 290

Query: 230 SNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKE 289
            N +S +  T       SQ   L+       H ++ + +    S +  N+T+   P    
Sbjct: 291 ENETSVLPPTPHAEQMVSQQRILI-------HEDSMNLLSLYTSPSLPNITLGL-PAVPS 342

Query: 290 LLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEP 340
            L +  +L   +   +Q + +   L       +   PAS S+  +  + +P
Sbjct: 343 QLNASNSLKEKQKCETQTLRQGVPLPGQYGGSI---PASSSHPHVTLEGKP 390


>gi|24431975 hypothetical protein LOC26148 [Homo sapiens]
          Length = 1247

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 17/183 (9%)

Query: 193  KPLQVKDESSAATKKLSATIPKA---TKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQN 249
            KP   +       K++S  +PKA   +K +    SS     N+   + A+ +  +  +  
Sbjct: 1061 KPKSTEGMKGRKGKQVSEILPKAEVQSKRKRTEGSSPPDSKNKGPTVKASKEKHADGATK 1120

Query: 250  TQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGII 309
            T   + P        RD   Q   +TS           K  +  K+A  S   S  +   
Sbjct: 1121 TPAAKRPA------ARDRSSQPPKKTSLK-------ENKVKIPKKSAGKSCPPSRKEKEN 1167

Query: 310  RNKTLSRSIASEVIARPASLSN-DKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERK 368
             NK  S+SIASE + +PA      +   + +    R+ ++GK      +  P+ ++ +RK
Sbjct: 1168 TNKRPSQSIASETLTKPAKQKGAGESSSRPQKATNRKQSSGKTRARPSTKTPESSAAQRK 1227

Query: 369  ARL 371
             +L
Sbjct: 1228 RKL 1230


>gi|45269141 multimerin 1 [Homo sapiens]
          Length = 1228

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 17/189 (8%)

Query: 413 EDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEP 472
           ED+ R F   +    S+ +N++     +E   +  ND+ + +    K V      +L E 
Sbjct: 365 EDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVS-----SLSED 419

Query: 473 ITSPIENIIAIYEKAILAGAQP----IEEMRHTIVDILTMKSQEKANLGENMEKSCASKE 528
           + S  + I  + E  +   AQ     ++E R T+ DI+ +++    N+ + M  +C  ++
Sbjct: 420 LESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRN-HIVNVRQEMTLTC--EK 476

Query: 529 EVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEK-----EQDNKTKDPTHDVKTPNTE 583
            +KE+ ++ T ++   E+    S L+   L +   K     EQ   T+  +     P  E
Sbjct: 477 PIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAE 536

Query: 584 TRTSCLIKY 592
           + ++ + +Y
Sbjct: 537 SVSNNVTEY 545


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 75/403 (18%), Positives = 144/403 (35%), Gaps = 42/403 (10%)

Query: 10  LQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGT 69
           LQ PP   A       R Q    HL   KT    K E +     +    +  + + + G+
Sbjct: 85  LQWPPIYTAA------REQTPFRHLYTSKTHLK-KAEYKKSKDEKGGTPLKKDSKKKGGS 137

Query: 70  KVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPH 129
                ++K   +E  KR  E+           PLK S+E   S     + +    +Q   
Sbjct: 138 YATNPESKQIVEEKTKRQNEADKT--------PLKSSHENEQSKKSKSSSETNPESQNSK 189

Query: 130 LLLT------EDDPQSQHMTLSQAFHLKNNSKK--KQMTTEKQKQDANMPKKPVLGSYRG 181
            +        + D ++   T ++  H KNN KK  K+  T          +  +   +  
Sbjct: 190 TVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLM 249

Query: 182 QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 241
            + QS   S      +++ S   +K  S    K TK           K N   +  A ++
Sbjct: 250 LVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKD--------TKKNAKKSSDAESE 301

Query: 242 FVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVK 301
                 ++++ V+  ++      +D  K+ + + + +     G  + E   +K     +K
Sbjct: 302 DSKDAKKDSKKVKKNVK------KDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLK 355

Query: 302 TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAI--VDSRSA- 358
               +     K    S  +E      + ++ + ++K+   D ++  A K     DS S  
Sbjct: 356 KDDKKK--DTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESEL 413

Query: 359 QPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEK 401
           + KE+ ++ K    + K    + +K    S     EP G ++K
Sbjct: 414 ESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKK 456


>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
          Length = 558

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 70/378 (18%), Positives = 144/378 (38%), Gaps = 47/378 (12%)

Query: 19  QSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQV-QEGTKVLKLKTK 77
           + A +E+RR+  +E L +       KQE E L    DQ  V +++ V  E  K     T+
Sbjct: 29  EEAARERRRRARQERLRQ-------KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 81

Query: 78  M------ADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLL 131
           +      A  E + R  E +   +  +  +  +   + T +   +     +  N T    
Sbjct: 82  VEGDDEAAFLERLARREERRQKRL--QEALERQKEFDPTITDASLSLPSRRMQNDTAENE 139

Query: 132 LTEDDPQSQHM----------TLSQAFHL---KNNSKKKQMTTEKQKQDANMPKKPVLGS 178
            TE + +S+            T+++++     ++  + K+   EK++++   PK+  +G 
Sbjct: 140 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGE 199

Query: 179 YRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTA 238
            +G+   +K+ + R+ LQ    +    +     I K  +P          K    S M  
Sbjct: 200 NQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEP----------KEEVKSFMDR 249

Query: 239 TTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKEL---LQSKT 295
              F    SQN + +   ++    +T +T  +   R S +    +G  + E    L+   
Sbjct: 250 KKGFTEVKSQNGEFMTHKLK----HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 305

Query: 296 ALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDS 355
                  S     ++ K    ++  E + +       K++E+ E   ++     K   + 
Sbjct: 306 RRRGETESEEFEKLKQKQQEAALELEELKKKRE-ERRKVLEEEEQRRKQEEADRKLREEE 364

Query: 356 RSAQPKETSEERKARLSE 373
              + KE  E R+A  +E
Sbjct: 365 EKRRLKEEIERRRAEAAE 382


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 70/378 (18%), Positives = 144/378 (38%), Gaps = 47/378 (12%)

Query: 19  QSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQV-QEGTKVLKLKTK 77
           + A +E+RR+  +E L +       KQE E L    DQ  V +++ V  E  K     T+
Sbjct: 35  EEAARERRRRARQERLRQ-------KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQ 87

Query: 78  M------ADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLL 131
           +      A  E + R  E +   +  +  +  +   + T +   +     +  N T    
Sbjct: 88  VEGDDEAAFLERLARREERRQKRL--QEALERQKEFDPTITDASLSLPSRRMQNDTAENE 145

Query: 132 LTEDDPQSQHM----------TLSQAFHL---KNNSKKKQMTTEKQKQDANMPKKPVLGS 178
            TE + +S+            T+++++     ++  + K+   EK++++   PK+  +G 
Sbjct: 146 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGE 205

Query: 179 YRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTA 238
            +G+   +K+ + R+ LQ    +    +     I K  +P          K    S M  
Sbjct: 206 NQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEP----------KEEVKSFMDR 255

Query: 239 TTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKEL---LQSKT 295
              F    SQN + +   ++    +T +T  +   R S +    +G  + E    L+   
Sbjct: 256 KKGFTEVKSQNGEFMTHKLK----HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 311

Query: 296 ALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDS 355
                  S     ++ K    ++  E + +       K++E+ E   ++     K   + 
Sbjct: 312 RRRGETESEEFEKLKQKQQEAALELEELKKKRE-ERRKVLEEEEQRRKQEEADRKLREEE 370

Query: 356 RSAQPKETSEERKARLSE 373
              + KE  E R+A  +E
Sbjct: 371 EKRRLKEEIERRRAEAAE 388


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 79/381 (20%), Positives = 139/381 (36%), Gaps = 59/381 (15%)

Query: 20   SAFKEQRRQK--LKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLK--LK 75
            S+  +QR Q   L+   +R + +  + Q  +  +S R      + D+ ++  K+ K  +K
Sbjct: 915  SSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDR------AHDENKKKAKIQKKPIK 968

Query: 76   TKMADKENMKR--------------PAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKP 121
             K  D   ++R              P + +    + K     K  +++++      + K 
Sbjct: 969  KKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKK- 1027

Query: 122  KDSNQTPHLLLTEDDPQSQHMTLSQAFHLKN----NSKKKQMTTEKQKQDANMPKKPVLG 177
            K   +TP +   E+        L +  + KN    +S+KK+ T      D ++P +  + 
Sbjct: 1028 KRGPRTPPITTKEE--------LVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVT 1079

Query: 178  SYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMT 237
                    +   S   PL             +AT   AT      T++    S  +S +T
Sbjct: 1080 EAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAA---TTAAAATSFSTSAIT 1136

Query: 238  ATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTAL 297
             +T    T + N         SH    R  V++     + +VTI    H K + Q     
Sbjct: 1137 ISTSATPTNTTNNTFANED--SHRKCHRTRVEKV---ETPHVTIEDAQHRKPMDQ----- 1186

Query: 298  SSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRS 357
               K SSS G       +RS  S    R  S SND      +    R+        D   
Sbjct: 1187 ---KRSSSLGS------NRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREK 1237

Query: 358  AQPKETSEERKARLSEWKAGK 378
             +  E + ERK+R+ + K G+
Sbjct: 1238 TKSLEITGERKSRIDQLKRGE 1258


>gi|65507253 hypothetical protein LOC55196 [Homo sapiens]
          Length = 1747

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 67/288 (23%), Positives = 111/288 (38%), Gaps = 39/288 (13%)

Query: 43  YKQENEMLSSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIP 102
           Y ++  M   S D +V+TS+    E T+ + L T+++ +   K   E  +  V     +P
Sbjct: 509 YSEKRPMPDPSHDVKVLTSKTSAVEMTQAV-LNTQLSSENVTK--VEQNSPAVCETISVP 565

Query: 103 LKPSNELTNSTVVIDTHKPKDSNQTPHLL-LTEDDPQSQHMTLSQAFHLKNNSKKKQ--- 158
              S E          +K K  N+   LL L     ++Q   L  A     +SK      
Sbjct: 566 KSMSTE---------EYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEM 616

Query: 159 ----MTTEKQKQDANMPKKPVLGSYRGQIVQSKI----NSFRKPLQVKDESSAATKKLSA 210
                 T  Q    NM + P   +  G+++ +       S  K +  K +SS + + L A
Sbjct: 617 NPNTQMTGNQLNLKNM-ETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVL-A 674

Query: 211 TIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQ 270
           T     K QP +T+         +N TA      +   N  +  P     +SN+++ +  
Sbjct: 675 TCLSLWKKQPSDTAKEKECDKLRTNTTAVG---ISKPANIHVKSPCSVVGNSNSQNKISN 731

Query: 271 GISRT----------SANVTIRKGPHEKELLQSKTALSSVKTSSSQGI 308
              +T          S+ + I KG   +  + S   LS VKT S +GI
Sbjct: 732 PSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGI 779


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 89/418 (21%), Positives = 152/418 (36%), Gaps = 38/418 (9%)

Query: 4   PAVPQDLQLP-PSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSE 62
           P+ PQ L  P  S  + SA  E             ++  +  +ENE L +   +    + 
Sbjct: 451 PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTT 510

Query: 63  DQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPK 122
           ++ Q    + K+    A  E   R  E        K       S E + S        PK
Sbjct: 511 NKWQLDNWLTKVSQPAAPPEG-PRSTEPPRRHPESKGSSDSATSQEHSESK----DPPPK 565

Query: 123 DSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRG- 181
            S++ P        P++ H            S  +Q   ++Q      PKKPV  S R  
Sbjct: 566 SSSKAPRA-----PPEAPHPGKRSC----QKSPAQQEPPQRQTVGTKQPKKPVKASARAG 616

Query: 182 --QIVQSKINSFRKPLQVKDESSAATKKLSAT-IPKA---TKPQPVNTSSVTVKSNRSSN 235
               +Q +      P   +D++S    K+     P+A    +P+P    S   K ++SS 
Sbjct: 617 SRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSS- 675

Query: 236 MTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGI------SRTSA---NVTIRKGPH 286
           + A +K +S        V      H +    T  QG       SRTS     V +++   
Sbjct: 676 LPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSR 735

Query: 287 EKEL---LQSKTALSSVK-TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVD 342
           +  L   L+    LS ++ T   Q ++   TL   + S +   P   S  +  E  +P  
Sbjct: 736 KDRLPLPLRDTKLLSPLRDTPPPQSLMVKITL--DLLSRIPQPPGKGSRQRKAEDKQPPA 793

Query: 343 QRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNE 400
            ++H++ K   DS S   K+   E +      K    + +K   +S  + H+ + + +
Sbjct: 794 GKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTK 851


>gi|18379328 WW domain-containing adapter with a coiled-coil region
           isoform 1 [Homo sapiens]
          Length = 647

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 10/134 (7%)

Query: 205 TKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVR-----PPIRS 259
           T  +S     +T+ QP N S +++ S+ SS  +  +  +ST   NT  ++     PP+ S
Sbjct: 417 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 476

Query: 260 HHSNTRDTVKQG---ISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSR 316
               +   VKQG    S T   VT  K    + +       SS + S S G   N T + 
Sbjct: 477 QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG--PNHTSNS 534

Query: 317 SIASEVIARPASLS 330
           S AS     P + S
Sbjct: 535 SNASNATVVPQNSS 548


>gi|18379332 WW domain-containing adapter with a coiled-coil region
           isoform 3 [Homo sapiens]
          Length = 544

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 10/134 (7%)

Query: 205 TKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVR-----PPIRS 259
           T  +S     +T+ QP N S +++ S+ SS  +  +  +ST   NT  ++     PP+ S
Sbjct: 314 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 373

Query: 260 HHSNTRDTVKQG---ISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSR 316
               +   VKQG    S T   VT  K    + +       SS + S S G   N T + 
Sbjct: 374 QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG--PNHTSNS 431

Query: 317 SIASEVIARPASLS 330
           S AS     P + S
Sbjct: 432 SNASNATVVPQNSS 445


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 56/293 (19%), Positives = 111/293 (37%), Gaps = 30/293 (10%)

Query: 47   NEMLSSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPS 106
            NE  + S  +     E       K +    K  + E M  P+ ++N T       P+KP+
Sbjct: 1010 NEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMT-PSANENTTPS-----PVKPT 1063

Query: 107  NE-----LTNSTVVIDTHKPKDSNQTPHLLLTEDDPQ----SQHMTLSQAFHLKNNSKKK 157
                   L N  + +    P +          +  P     ++H   + + + K  S   
Sbjct: 1064 EHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAA 1123

Query: 158  QMTTEKQKQ-DANM----PKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATI 212
            + T  + +   AN+    P +P+  + R  +   K+       QV ++S+   +K ++T 
Sbjct: 1124 ESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMT------QVTEKSTEHPEKTTSTT 1177

Query: 213  PKAT----KPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTV 268
             K T    KP   +  ++  K   +      T+ +  T+  T+ ++ P++S  +  +   
Sbjct: 1178 EKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAA 1237

Query: 269  KQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASE 321
                 + S  VT  K         +KT ++    + S  +I ++T   SI SE
Sbjct: 1238 VTKTIKPSVKVTGDKSLTTTSSHLNKTEVTHQVPTGSFTLITSRTKLSSITSE 1290


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 9/117 (7%)

Query: 198  KDESSAATKKLSATIPK--------ATKPQPVNTSSVTVKSNRSSNMTAT-TKFVSTTSQ 248
            K  +   T  +SAT+PK        +T     NT+S T+ +   +  T+T T   +T   
Sbjct: 1121 KTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFT 1180

Query: 249  NTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSS 305
             T  +        ++T D+    IS  ++  T+   P       ++T  +SV T++S
Sbjct: 1181 TTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTS 1237


>gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens]
          Length = 1173

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 50/229 (21%), Positives = 92/229 (40%), Gaps = 33/229 (14%)

Query: 19  QSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLK---LK 75
           Q+ F E+R++   +  L+            M+  +R+  +    D   +  K +K   LK
Sbjct: 329 QNKFPEKRKRNSVDSDLK-------STRESMIPKARESFLEKRPDGPHQKEKFIKHIALK 381

Query: 76  TK---MADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLL 132
           T    +  ++  K P++  + +  G     L PSN   +       H  ++S+Q      
Sbjct: 382 TPGDVLRLEDISKEPSDETDGSSAG-----LAPSNSGNSGH-----HSTRNSDQIQVAGT 431

Query: 133 TEDDPQSQHMTLSQ-------AFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQ 185
            E   Q  H+ LSQ       A +L+ N      T EK+ +   + + P  GS    +V 
Sbjct: 432 KETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGS---SLVP 488

Query: 186 SKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSS 234
               +   P+  KD+  +++K+ S    ++TK +     +    SN SS
Sbjct: 489 LNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSS 537


>gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens]
          Length = 1186

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 50/229 (21%), Positives = 92/229 (40%), Gaps = 33/229 (14%)

Query: 19  QSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLK---LK 75
           Q+ F E+R++   +  L+            M+  +R+  +    D   +  K +K   LK
Sbjct: 329 QNKFPEKRKRNSVDSDLK-------STRESMIPKARESFLEKRPDGPHQKEKFIKHIALK 381

Query: 76  TK---MADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLL 132
           T    +  ++  K P++  + +  G     L PSN   +       H  ++S+Q      
Sbjct: 382 TPGDVLRLEDISKEPSDETDGSSAG-----LAPSNSGNSGH-----HSTRNSDQIQVAGT 431

Query: 133 TEDDPQSQHMTLSQ-------AFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQ 185
            E   Q  H+ LSQ       A +L+ N      T EK+ +   + + P  GS    +V 
Sbjct: 432 KETKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGS---SLVP 488

Query: 186 SKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSS 234
               +   P+  KD+  +++K+ S    ++TK +     +    SN SS
Sbjct: 489 LNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSS 537


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.124    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,103,768
Number of Sequences: 37866
Number of extensions: 1125310
Number of successful extensions: 4569
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 216
Number of HSP's that attempted gapping in prelim test: 4263
Number of HSP's gapped (non-prelim): 521
length of query: 683
length of database: 18,247,518
effective HSP length: 109
effective length of query: 574
effective length of database: 14,120,124
effective search space: 8104951176
effective search space used: 8104951176
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.