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Search of human proteins with 148528998
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148528998 Dmx-like 1 [Homo sapiens]
(3027 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148528998 Dmx-like 1 [Homo sapiens] 6115 0.0
gi|119120894 Dmx-like 2 [Homo sapiens] 3245 0.0
gi|19913369 transducin beta-like 3 [Homo sapiens] 57 3e-07
gi|13376840 WD repeat domain 61 [Homo sapiens] 55 1e-06
gi|26665869 WD repeat domain 51B [Homo sapiens] 54 3e-06
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 52 7e-06
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 52 7e-06
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 52 7e-06
gi|21536371 telomerase-associated protein 1 [Homo sapiens] 49 8e-05
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 49 8e-05
gi|21071067 TBP-associated factor 5 [Homo sapiens] 47 2e-04
gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens] 47 3e-04
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 46 5e-04
gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [H... 45 8e-04
gi|18874090 WD repeat domain 48 [Homo sapiens] 45 8e-04
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 45 0.001
gi|32189425 WD repeat domain 69 [Homo sapiens] 45 0.001
gi|148536855 coatomer protein complex, subunit alpha isoform 1 [... 45 0.001
gi|148536853 coatomer protein complex, subunit alpha isoform 2 [... 45 0.001
gi|23199987 WD repeat domain 5B [Homo sapiens] 45 0.001
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 45 0.001
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 45 0.001
gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [... 45 0.001
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 44 0.002
gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] 44 0.002
gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] 44 0.002
gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] 44 0.002
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 44 0.003
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 44 0.003
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 44 0.003
>gi|148528998 Dmx-like 1 [Homo sapiens]
Length = 3027
Score = 6115 bits (15865), Expect = 0.0
Identities = 3027/3027 (100%), Positives = 3027/3027 (100%)
Query: 1 MNLHQVLTGAVNPGDHCFSVGSIGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQV 60
MNLHQVLTGAVNPGDHCFSVGSIGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQV
Sbjct: 1 MNLHQVLTGAVNPGDHCFSVGSIGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQV 60
Query: 61 GCVDCSMQQGKIAASYGNVISIFEPVNLPKQKKNLELYSQWQKSGQFFLESIAHNITWDP 120
GCVDCSMQQGKIAASYGNVISIFEPVNLPKQKKNLELYSQWQKSGQFFLESIAHNITWDP
Sbjct: 61 GCVDCSMQQGKIAASYGNVISIFEPVNLPKQKKNLELYSQWQKSGQFFLESIAHNITWDP 120
Query: 121 TGSRLLTGSSYLQLWSNTNLEKPTEDENLNKTDLNFGDWKCIWHCKTASQVHLMKFSPDG 180
TGSRLLTGSSYLQLWSNTNLEKPTEDENLNKTDLNFGDWKCIWHCKTASQVHLMKFSPDG
Sbjct: 121 TGSRLLTGSSYLQLWSNTNLEKPTEDENLNKTDLNFGDWKCIWHCKTASQVHLMKFSPDG 180
Query: 181 EFFATAGKDDCLLKVWYNVENWRTAVTSPDGSSEKQSQGEIDFSFVYLAHPRAVNGFSWR 240
EFFATAGKDDCLLKVWYNVENWRTAVTSPDGSSEKQSQGEIDFSFVYLAHPRAVNGFSWR
Sbjct: 181 EFFATAGKDDCLLKVWYNVENWRTAVTSPDGSSEKQSQGEIDFSFVYLAHPRAVNGFSWR 240
Query: 241 KTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTESINLTNNFKRNA 300
KTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTESINLTNNFKRNA
Sbjct: 241 KTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTESINLTNNFKRNA 300
Query: 301 SSKERVQNALEVNLRHFRRGRRRSLALVAHTGYLPHQQDPHHVHRNTPLHANALCHFHIA 360
SSKERVQNALEVNLRHFRRGRRRSLALVAHTGYLPHQQDPHHVHRNTPLHANALCHFHIA
Sbjct: 301 SSKERVQNALEVNLRHFRRGRRRSLALVAHTGYLPHQQDPHHVHRNTPLHANALCHFHIA 360
Query: 361 ASINPATDIPLLPSITSLSLNENEEKTGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQP 420
ASINPATDIPLLPSITSLSLNENEEKTGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQP
Sbjct: 361 ASINPATDIPLLPSITSLSLNENEEKTGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQP 420
Query: 421 SSEASVEDSNQADVKSDEETDDGVDDLKINPEKKELGCDKMVPNSSFTSLSSAAIDHQIE 480
SSEASVEDSNQADVKSDEETDDGVDDLKINPEKKELGCDKMVPNSSFTSLSSAAIDHQIE
Sbjct: 421 SSEASVEDSNQADVKSDEETDDGVDDLKINPEKKELGCDKMVPNSSFTSLSSAAIDHQIE 480
Query: 481 VLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDAN 540
VLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDAN
Sbjct: 481 VLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDAN 540
Query: 541 SLCKSIMMYACTKNVDLAIQQGKQKPSGLTRSTSMLISSGHNKSSNSLKLSIFTPNVMMI 600
SLCKSIMMYACTKNVDLAIQQGKQKPSGLTRSTSMLISSGHNKSSNSLKLSIFTPNVMMI
Sbjct: 541 SLCKSIMMYACTKNVDLAIQQGKQKPSGLTRSTSMLISSGHNKSSNSLKLSIFTPNVMMI 600
Query: 601 SKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNA 660
SKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNA
Sbjct: 601 SKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNA 660
Query: 661 LRTPDVDNPEQPFDALNIEECSLTQQNKSTVDVAFQDPSAVYSELILWRVDPVGPLSFSG 720
LRTPDVDNPEQPFDALNIEECSLTQQNKSTVDVAFQDPSAVYSELILWRVDPVGPLSFSG
Sbjct: 661 LRTPDVDNPEQPFDALNIEECSLTQQNKSTVDVAFQDPSAVYSELILWRVDPVGPLSFSG 720
Query: 721 GVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAK 780
GVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAK
Sbjct: 721 GVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAK 780
Query: 781 KLLSELSNPEISKYVGEVFNIVSQQSTARPGCIIALDPITKLHGRKTQLLHVFEEDFILN 840
KLLSELSNPEISKYVGEVFNIVSQQSTARPGCIIALDPITKLHGRKTQLLHVFEEDFILN
Sbjct: 781 KLLSELSNPEISKYVGEVFNIVSQQSTARPGCIIALDPITKLHGRKTQLLHVFEEDFILN 840
Query: 841 NLEKKSLGKDSILSNAGSSPNGFSEKFYLIVIECTQDNRSLLHMWNLHLKSIPVSLDEKV 900
NLEKKSLGKDSILSNAGSSPNGFSEKFYLIVIECTQDNRSLLHMWNLHLKSIPVSLDEKV
Sbjct: 841 NLEKKSLGKDSILSNAGSSPNGFSEKFYLIVIECTQDNRSLLHMWNLHLKSIPVSLDEKV 900
Query: 901 DTKLSEAVWQPEEHYSSSPEKILSPFSQKYQACRANLQSTSRLTLFSEMVYSQELHLPEG 960
DTKLSEAVWQPEEHYSSSPEKILSPFSQKYQACRANLQSTSRLTLFSEMVYSQELHLPEG
Sbjct: 901 DTKLSEAVWQPEEHYSSSPEKILSPFSQKYQACRANLQSTSRLTLFSEMVYSQELHLPEG 960
Query: 961 VEIISIKPSAGHLSSSSIYPACSAPYLLATSCSDEKVRFWRCRVTDGESATSKNGKIDLA 1020
VEIISIKPSAGHLSSSSIYPACSAPYLLATSCSDEKVRFWRCRVTDGESATSKNGKIDLA
Sbjct: 961 VEIISIKPSAGHLSSSSIYPACSAPYLLATSCSDEKVRFWRCRVTDGESATSKNGKIDLA 1020
Query: 1021 YIWEEWPLLIEDGLQSNSSITVPGRPVEVSCAHTNRLAVAYKQPASNSRSSQDFVMHVSI 1080
YIWEEWPLLIEDGLQSNSSITVPGRPVEVSCAHTNRLAVAYKQPASNSRSSQDFVMHVSI
Sbjct: 1021 YIWEEWPLLIEDGLQSNSSITVPGRPVEVSCAHTNRLAVAYKQPASNSRSSQDFVMHVSI 1080
Query: 1081 FECESTGGSCWVLEQTIHLDELSTVLDSGISVDSNLVAYNKQDMYLSSKENITSNTKHLV 1140
FECESTGGSCWVLEQTIHLDELSTVLDSGISVDSNLVAYNKQDMYLSSKENITSNTKHLV
Sbjct: 1081 FECESTGGSCWVLEQTIHLDELSTVLDSGISVDSNLVAYNKQDMYLSSKENITSNTKHLV 1140
Query: 1141 HLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQDQTGKETLAFPLWESTKVVPLSKFVLL 1200
HLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQDQTGKETLAFPLWESTKVVPLSKFVLL
Sbjct: 1141 HLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQDQTGKETLAFPLWESTKVVPLSKFVLL 1200
Query: 1201 RSVDLVSSVDGSPPFPVSLSWVRDGILVVGMDCEMHVYCQWQPSSKQEPVITDSYSGSTP 1260
RSVDLVSSVDGSPPFPVSLSWVRDGILVVGMDCEMHVYCQWQPSSKQEPVITDSYSGSTP
Sbjct: 1201 RSVDLVSSVDGSPPFPVSLSWVRDGILVVGMDCEMHVYCQWQPSSKQEPVITDSYSGSTP 1260
Query: 1261 SITSLIKQSNSSSGLHPPKKTLTRSMTSLAQKICGKKTAFDPSVDMEDSGLFEAAHVLSP 1320
SITSLIKQSNSSSGLHPPKKTLTRSMTSLAQKICGKKTAFDPSVDMEDSGLFEAAHVLSP
Sbjct: 1261 SITSLIKQSNSSSGLHPPKKTLTRSMTSLAQKICGKKTAFDPSVDMEDSGLFEAAHVLSP 1320
Query: 1321 TLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNEAESNHERRLRSLTISASG 1380
TLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNEAESNHERRLRSLTISASG
Sbjct: 1321 TLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNEAESNHERRLRSLTISASG 1380
Query: 1381 STTRDPQAFNKAENTDYTEIDSVPPLPLYALLAADDDSCYSSLEKSSNESTLSKSNQLSK 1440
STTRDPQAFNKAENTDYTEIDSVPPLPLYALLAADDDSCYSSLEKSSNESTLSKSNQLSK
Sbjct: 1381 STTRDPQAFNKAENTDYTEIDSVPPLPLYALLAADDDSCYSSLEKSSNESTLSKSNQLSK 1440
Query: 1441 ESYDELFQTQLLMTDTHMLETDEENTKPRVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPG 1500
ESYDELFQTQLLMTDTHMLETDEENTKPRVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPG
Sbjct: 1441 ESYDELFQTQLLMTDTHMLETDEENTKPRVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPG 1500
Query: 1501 LSRMEQMSLMALADTIATTSTDIGESRDRSQGGETLDECGLKFLLAVRLHTFLTTSLPAY 1560
LSRMEQMSLMALADTIATTSTDIGESRDRSQGGETLDECGLKFLLAVRLHTFLTTSLPAY
Sbjct: 1501 LSRMEQMSLMALADTIATTSTDIGESRDRSQGGETLDECGLKFLLAVRLHTFLTTSLPAY 1560
Query: 1561 RAQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRK 1620
RAQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRK
Sbjct: 1561 RAQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRK 1620
Query: 1621 CIEKVAKAAFYRKNDPLDAAIFYLAMKKKAVIWGLYRAEKNTRMTQFFGHNFEDERWRKA 1680
CIEKVAKAAFYRKNDPLDAAIFYLAMKKKAVIWGLYRAEKNTRMTQFFGHNFEDERWRKA
Sbjct: 1621 CIEKVAKAAFYRKNDPLDAAIFYLAMKKKAVIWGLYRAEKNTRMTQFFGHNFEDERWRKA 1680
Query: 1681 ALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSAA 1740
ALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSAA
Sbjct: 1681 ALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSAA 1740
Query: 1741 YKSILRKKVLGIDSPVSELCSLNINMHHDPFLRSMAYWILEDYSGALETLIKQPIRENDD 1800
YKSILRKKVLGIDSPVSELCSLNINMHHDPFLRSMAYWILEDYSGALETLIKQPIRENDD
Sbjct: 1741 YKSILRKKVLGIDSPVSELCSLNINMHHDPFLRSMAYWILEDYSGALETLIKQPIRENDD 1800
Query: 1801 QVLSASNPTVFNFYNYLRTHPLLLRRHFGSSDTFSTHMSLTGKSGLAGTINLSERRLFFT 1860
QVLSASNPTVFNFYNYLRTHPLLLRRHFGSSDTFSTHMSLTGKSGLAGTINLSERRLFFT
Sbjct: 1801 QVLSASNPTVFNFYNYLRTHPLLLRRHFGSSDTFSTHMSLTGKSGLAGTINLSERRLFFT 1860
Query: 1861 TASAHLKAGCPMLALEVLSKMPKVIKKTRPFYRASSFLDTSKDCSPSSPLKLDAREDKSS 1920
TASAHLKAGCPMLALEVLSKMPKVIKKTRPFYRASSFLDTSKDCSPSSPLKLDAREDKSS
Sbjct: 1861 TASAHLKAGCPMLALEVLSKMPKVIKKTRPFYRASSFLDTSKDCSPSSPLKLDAREDKSS 1920
Query: 1921 AVDWSQSLINGFGSSSEGSSEKQSNSTLSFDWSQPSVVFQDDSLELKWDSDNDEENEDVP 1980
AVDWSQSLINGFGSSSEGSSEKQSNSTLSFDWSQPSVVFQDDSLELKWDSDNDEENEDVP
Sbjct: 1921 AVDWSQSLINGFGSSSEGSSEKQSNSTLSFDWSQPSVVFQDDSLELKWDSDNDEENEDVP 1980
Query: 1981 ISMKELKPLQRKTDKKLDDISSNYTESFSTLDENDLLNPSEDIIAVQLKFRACLKILTVE 2040
ISMKELKPLQRKTDKKLDDISSNYTESFSTLDENDLLNPSEDIIAVQLKFRACLKILTVE
Sbjct: 1981 ISMKELKPLQRKTDKKLDDISSNYTESFSTLDENDLLNPSEDIIAVQLKFRACLKILTVE 2040
Query: 2041 LRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDFCSDAEELQSAFGRNEDEFGLNEDA 2100
LRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDFCSDAEELQSAFGRNEDEFGLNEDA
Sbjct: 2041 LRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDFCSDAEELQSAFGRNEDEFGLNEDA 2100
Query: 2101 EDLPHQTKVKQLRENFQEKRQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQE 2160
EDLPHQTKVKQLRENFQEKRQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQE
Sbjct: 2101 EDLPHQTKVKQLRENFQEKRQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQE 2160
Query: 2161 SQQETSEPLFSSPLSEQTSVPLLFACTANAKTVVANPLLHLSNLTHDILHAIINFDSPPH 2220
SQQETSEPLFSSPLSEQTSVPLLFACTANAKTVVANPLLHLSNLTHDILHAIINFDSPPH
Sbjct: 2161 SQQETSEPLFSSPLSEQTSVPLLFACTANAKTVVANPLLHLSNLTHDILHAIINFDSPPH 2220
Query: 2221 PDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMVYQTVLLPHRPSLKTGS 2280
PDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMVYQTVLLPHRPSLKTGS
Sbjct: 2221 PDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMVYQTVLLPHRPSLKTGS 2280
Query: 2281 LDEALTPNTSPAQWPGITCLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSS 2340
LDEALTPNTSPAQWPGITCLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSS
Sbjct: 2281 LDEALTPNTSPAQWPGITCLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSS 2340
Query: 2341 NELFRIVAHPLNEKMWSAVFGGGAHVPSKEQTHSKTLPVSSLVEEGEKQNKRFRPSKMSC 2400
NELFRIVAHPLNEKMWSAVFGGGAHVPSKEQTHSKTLPVSSLVEEGEKQNKRFRPSKMSC
Sbjct: 2341 NELFRIVAHPLNEKMWSAVFGGGAHVPSKEQTHSKTLPVSSLVEEGEKQNKRFRPSKMSC 2400
Query: 2401 RESAPLTPSSAPVSQESLAVKEKFIPPELSIWDYFIAKPFLPSSQSRAEYDSEESLGSDD 2460
RESAPLTPSSAPVSQESLAVKEKFIPPELSIWDYFIAKPFLPSSQSRAEYDSEESLGSDD
Sbjct: 2401 RESAPLTPSSAPVSQESLAVKEKFIPPELSIWDYFIAKPFLPSSQSRAEYDSEESLGSDD 2460
Query: 2461 DDNDDDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLNNLKTFYPFAGHDLAELPVSS 2520
DDNDDDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLNNLKTFYPFAGHDLAELPVSS
Sbjct: 2461 DDNDDDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLNNLKTFYPFAGHDLAELPVSS 2520
Query: 2521 PLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTAEESLSAGPAILRHKALLEPTNTP 2580
PLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTAEESLSAGPAILRHKALLEPTNTP
Sbjct: 2521 PLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTAEESLSAGPAILRHKALLEPTNTP 2580
Query: 2581 FKSKHHLALSVKRLWQYLVKQEEIQETFIKNIFTKKRCLNEIEADLGYPGGKARIIHKES 2640
FKSKHHLALSVKRLWQYLVKQEEIQETFIKNIFTKKRCLNEIEADLGYPGGKARIIHKES
Sbjct: 2581 FKSKHHLALSVKRLWQYLVKQEEIQETFIKNIFTKKRCLNEIEADLGYPGGKARIIHKES 2640
Query: 2641 DIITAFAVNKANRNCIAIASSHDVQELDVSGILATQVYTWVDDDIEVETKGSEDFLVIHA 2700
DIITAFAVNKANRNCIAIASSHDVQELDVSGILATQVYTWVDDDIEVETKGSEDFLVIHA
Sbjct: 2641 DIITAFAVNKANRNCIAIASSHDVQELDVSGILATQVYTWVDDDIEVETKGSEDFLVIHA 2700
Query: 2701 RDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKKAINNVRRMTSHPTLPYYL 2760
RDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKKAINNVRRMTSHPTLPYYL
Sbjct: 2701 RDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKKAINNVRRMTSHPTLPYYL 2760
Query: 2761 TGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKC 2820
TGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKC
Sbjct: 2761 TGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKC 2820
Query: 2821 CPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVH 2880
CPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVH
Sbjct: 2821 CPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVH 2880
Query: 2881 AFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTE 2940
AFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTE
Sbjct: 2881 AFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTE 2940
Query: 2941 EYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGAD 3000
EYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGAD
Sbjct: 2941 EYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGAD 3000
Query: 3001 GTMKMRILPDQFSPLNEVLKNDVKFML 3027
GTMKMRILPDQFSPLNEVLKNDVKFML
Sbjct: 3001 GTMKMRILPDQFSPLNEVLKNDVKFML 3027
>gi|119120894 Dmx-like 2 [Homo sapiens]
Length = 3036
Score = 3245 bits (8413), Expect = 0.0
Identities = 1708/3097 (55%), Positives = 2155/3097 (69%), Gaps = 142/3097 (4%)
Query: 1 MNLHQVLTGAVNPGDHCFSVGSIGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQV 60
M+LHQVLTGAVNPGD+C+SVGS+GD FTAY SGCDIVIL +DFE +QIIPGAKHGNIQV
Sbjct: 1 MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV 60
Query: 61 GCVDCSMQQGKIAASYGNVISIFEPVNLPKQKKNLELYSQWQKSGQFFLESIAHNITWDP 120
CV+CS QQG+IAASYGN + IFEP+ + K+N +L QW K+GQFFL S+ +N+ WDP
Sbjct: 61 SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP 120
Query: 121 TGSRLLTGSSYLQLWSNTNLEKPTEDENLNKT-DLNFGDWKCIWHCKTASQVHLMKFSPD 179
+RLLT + +QLW+ + E+E ++ T DWKC+W CKT+ VHLM++SPD
Sbjct: 121 QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD 180
Query: 180 GEFFATAGKDDCLLKVWYNVENWRTAVTSPDGSSEKQSQGEIDFSFVYLAHPRAVNGFSW 239
GE+FATAGKDDCLLKVWY + W++++ D K+ Q FSFVYLAHPRAV GFSW
Sbjct: 181 GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW 240
Query: 240 RKTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTESINLTNNFKRN 299
RKTSKYMPR SVCNVLLT C D VCRLW ET LP DCLL C T SI ++
Sbjct: 241 RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSI--ASSLSHA 298
Query: 300 ASSKERVQNALEV--NLRHFRRGRRRSLALVAHTGYLPHQQDPHHVHRNTPLHANALCHF 357
K+R+Q+ALE +L++ R+G+RRS LV H +P Q H V R+ HANALCHF
Sbjct: 299 GRHKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHF 358
Query: 358 HIAASINPATDIPLLPSITSLSLNENEEKTGPFVVHWLNNKELHFTLSMEVFLQQLRK-- 415
HIAASINPATDIP + T+ ++++ G FVVHWLNNKE HFT S EVF+ QLRK
Sbjct: 359 HIAASINPATDIPNVLVGTAFNVDDGN---GGFVVHWLNNKEFHFTSSTEVFMHQLRKLS 415
Query: 416 ---------SFEQPSSEASVEDSNQA-------DVKSDEETDDGVDDLKINPEKKELGCD 459
++ E S ED + D+ D E++ G + ++E
Sbjct: 416 DKQVDHENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPR 475
Query: 460 KMVPNSSFTSLSSAAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMF 519
S L + +D +IE LL+EW+KN DMLF+IHP+DG+ LVWHV +LDEY PG+F
Sbjct: 476 TYSRLSVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIF 535
Query: 520 RQVQVSFVSRIPVAFPTGDANSLCKSIMMYACTKNVDLAIQQGKQKPSGLTRSTSMLISS 579
RQVQVSF SRIPVAFP+GDA+SL K+IMMYAC I K L M + S
Sbjct: 536 RQVQVSFSSRIPVAFPSGDASSLSKNIMMYAC-------INATKDSHHTLLHQEGMSVGS 588
Query: 580 GHNKS----SNSLKLSIFTPNVMMISKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCG 635
H S+S ++I P VMMISKH DGSLNQW V+FA++SAF+TVL++SHK RYCG
Sbjct: 589 PHGSQPHSRSHSTHMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCG 648
Query: 636 HRFHLNDLACHSVLPLLLTTSHHNALRTPDVD-------NPEQPFDALNIEECSLTQQNK 688
HRFHLNDLACHSVLPLLLT+SHHNAL TP++D + D + + S Q +
Sbjct: 649 HRFHLNDLACHSVLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLR 708
Query: 689 STVDVAFQDPSAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPS 748
+ F DP+A+YSELILWRVDP+GPLS++GGVSELARINSLH SAFSNVAWLPTLIPS
Sbjct: 709 NAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPS 768
Query: 749 YCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLSELSNPEISKYVGEVFNIVSQQSTA 808
YCLG YCNS SACFVASDG+ LRLY+AV+DA+KLL ELS+PE SK +GEVFNIVSQQSTA
Sbjct: 769 YCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTA 828
Query: 809 RPGCIIALDPITKLHGRKTQLLHVFEEDFILN------NLEKKSLGKDSILSNAGSSPNG 862
RPGCII LD IT G TQLLHVF+EDFI+ ++EKK + + G P
Sbjct: 829 RPGCIIELDAITNQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKET-EIFFQPSQGYRPPP 887
Query: 863 FSEKFYLIVIECTQDNRSLLHMWNLHLKSIPVSLDEKVDTKLSEAVWQP--EEHYSSSPE 920
FSEKF+L+VIE +N S+LHMW+LHLKS+ L + + SE++ +++ SSPE
Sbjct: 888 FSEKFFLVVIEKDSNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPE 947
Query: 921 KILSPFSQKYQACRANLQSTSRLTLFSEMVYSQELHLPEGVEIISIKPSAGHLSSSSIYP 980
S + + ANLQ+ S+L L S +VYSQ L LPE VE+I PSAGHLSSSSIYP
Sbjct: 948 TSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYP 1007
Query: 981 ACSAPYLLATSCSDEKVRFWRCRVTDGESATSKNGKIDLAYIWEEWPLLIEDGLQSNSSI 1040
C APYL+ T+CSD KVRFW+C + + K Y W+ WPL+ ++G ++S++
Sbjct: 1008 VCLAPYLVVTTCSDNKVRFWKCCMEANPECNKSDEKE--IYHWKRWPLMNDEGEDNSSTV 1065
Query: 1041 TVPGRPVEVSCAHTNRLAVAYKQPAS-NSRSSQDFVMHVSIFECESTGGSCWVLEQTIHL 1099
++ GRPV VSC++T RLAVAYKQP N S++F MHV IFECESTGGS WVLEQTIHL
Sbjct: 1066 SIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHL 1125
Query: 1100 DEL---STVLDSGISVDSNLVAYNKQDMYLSSKENITSNTKHLVHLDWMSREDGSHILTV 1156
D+L +VLDS +SVDSNL Y+K D LS + N KHLVHLDW+S+EDGSHILTV
Sbjct: 1126 DDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTV 1185
Query: 1157 GIGSKLFMYGPLAGKVQDQT----GKETLAFPLWESTKVVPLSKFVLLRSVDLVSSVDGS 1212
G+G+ +FMYG L+G V +QT G + PL S K S++VLLRS+DLVSSVDG+
Sbjct: 1186 GVGANIFMYGRLSGIVTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGT 1245
Query: 1213 PPFPVSLSWVRDGILVVGMDCEMHVYCQWQPSSKQEPVITDSYSGSTPSITSLIKQSNSS 1272
P PVSLSWVRDGILVVGMDCEMHVY QW+ + K DS SN+
Sbjct: 1246 PSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDTEADS--------------SNAE 1291
Query: 1273 SGLHPPKKTLTRSMTSLAQKICGKKTAFDPSVD-----MEDSGLFEAAHVLSPTLPQYHP 1327
T +M LA+K + TA V ++D GLFEAAHVLSPTLPQYHP
Sbjct: 1292 EAAMQDHSTFKSNM--LARKSVVEGTAISDDVFCSPTVIQDGGLFEAAHVLSPTLPQYHP 1349
Query: 1328 LQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNEAESNH-ERRLRSLTISASGSTTRDP 1386
QLLELMDLGKVRRAKAILSHLVKCIAGEV + + ++ +R S TIS SGST ++
Sbjct: 1350 TQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKET 1409
Query: 1387 QAFNKAENTDYTEIDSVPPLPLYALLAADDDSCYSSLEKSSN--ESTLSKSNQLSKESYD 1444
K DYTEIDS+PPLPLYALLAAD D+ Y E+S+ +S ++ ++ Y
Sbjct: 1410 VTVGKDGTRDYTEIDSIPPLPLYALLAADQDTSYRISEESTKIPQSYEDQTVSQPEDQYS 1469
Query: 1445 ELFQTQLLMTDTHMLETDEENTKPRVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPGLSRM 1504
ELFQ Q + TD LE ++ K +VI+LSQY P YFG EHA+VLS HL+HSSLPGL+R+
Sbjct: 1470 ELFQIQDIPTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRL 1529
Query: 1505 EQMSLMALADTIATTSTDIGESRDRS-QGGETLDECGLKFLLAVRLHTFLTTSLPA-YRA 1562
EQM L+ALADT+ATTST++ ESRD+S G +TLDECGL++LLA+RLHT L TSLP YR
Sbjct: 1530 EQMFLVALADTVATTSTELDESRDKSCSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRV 1589
Query: 1563 QLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRKCI 1622
QLLHQG+ST HFAWAFHS AEEEL+NM+PA+Q+ DP WSELRAMG+GWWVRN LR+CI
Sbjct: 1590 QLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCI 1649
Query: 1623 EKVAKAAFYRKNDPLDAAIFYLAMKKKAVIWGLYRAEKNTRMTQFFGHNFEDERWRKAAL 1682
EKVAKA+F R ND LDAA+FYL+MKKKAV+WGL+R++ + +MT FF HNF ++RWRKAAL
Sbjct: 1650 EKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAAL 1709
Query: 1683 KNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSAAYK 1742
KNAFSLLGKQRFE SAAFFLLAG L+DAIEVCLEK+ DIQLA+VIARLYESEF+TS+ Y
Sbjct: 1710 KNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSSTYI 1769
Query: 1743 SILRKKVLGIDSPVSEL-CSLNINMHHDPFLRSMAYWILEDYSGALETLIKQPIRENDDQ 1801
SIL +K+LG S C +H DPFLRS+AYW+++DY+ AL+TL++Q +E+D+
Sbjct: 1770 SILNQKILGCQKDGSGFSCK---RLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEH 1826
Query: 1802 --VLSASNPTVFNFYNYLRTHPLLLRRHFGSSDTFSTHMSLTGKSGLAGTINLSERRLFF 1859
++ + NP F+FYNYLRTHPLL+RR+ S + + L + INL ER+LFF
Sbjct: 1827 QVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFF 1886
Query: 1860 TTASAHLKAGCPMLALEVLSKMPKVIKKTRPFYRASSFLDTSKDCSPSSPLKLDAREDKS 1919
TTA+AH K GCP+LALEVLSK+PKV K +S L KD P + R D
Sbjct: 1887 TTANAHFKVGCPVLALEVLSKIPKVTK--------TSALSAKKD----QPDFISHRMD-- 1932
Query: 1920 SAVDWSQSLINGFGSSSEGSSEKQSNSTLSFDWSQPSVVFQDDSLELKWDSDND---EEN 1976
S++L +G GSS E + ++ +DWSQP V ++ L L W D+D +E
Sbjct: 1933 DVPSHSKALSDGNGSS---GIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGEDHDSALDEE 1989
Query: 1977 EDVPISMKELKPLQRKTDKKLDDISSNYTESFSTLDENDLLNPSE-DIIAVQLKFRACLK 2035
ED + + R+ DK+ D +S+ + +E+D +E D+IA QLKFRACLK
Sbjct: 1990 EDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAEQLKFRACLK 2049
Query: 2036 ILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDFCSDAEELQS-AFGRNEDEF 2094
IL ELRTL+TGYE+DGGKLR+QLY+WLEKE+ AL C+ S +E S + + E +
Sbjct: 2050 ILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESDL 2109
Query: 2095 GLNEDAEDLP-------HQTKVKQL---RENFQEKRQWLLKYQSLLRMFLSYCILHGSHG 2144
E+ D P HQ + ++L RE+ + ++ WL K Q LLR+FLSYC LHG+ G
Sbjct: 2110 LDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLSYCSLHGAQG 2169
Query: 2145 GGLASVRMELILLLQESQQETSEPLFSSPLSEQTSVPLLFACTANAKTVVANPLLHLSNL 2204
GGLASVRMEL LLQESQQET+ SPL T++PLL A A+ KTV+ANP+L+L+N
Sbjct: 2170 GGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNH 2229
Query: 2205 THDILHAIINFDSPPHPDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMV 2264
HDIL+ I+ +PPHP I+ KV+ +H+LAASLSA IYQ LC SH+YS + NQFTGM
Sbjct: 2230 IHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMA 2289
Query: 2265 YQTVLLPHRPSLKTGSLDEALTPNTSPAQWPGITCLIRLLNSSGEEAQSGLTVLLCEILT 2324
YQ +LL R L+T S++E TPN+SPAQWPG++ LI LL+S+ +E Q L +LLCE +
Sbjct: 2290 YQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNILLCEAVV 2349
Query: 2325 AVYLSLFIHGLATHSSNELFRIVAHPLNEKMWSAVFGGGAHVPSKEQTHSKTLPVSSLVE 2384
AVYLSL IH LAT+SS+ELFR+ AHPLN +MW+AVFGGG + K + S+ + ++
Sbjct: 2350 AVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSENISAPPVLS 2409
Query: 2385 EGEKQNKRFRPSKMSCRESAPLTPSSAPVSQESLAVKEKFIPPELSIWDYFIAKPFLPSS 2444
E +++R +M + PV E + KEKFIPPELS+WDYF+AKPFLP S
Sbjct: 2410 EDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLS 2469
Query: 2445 QSRAEYDSEESLGSDDDDNDDDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLNNLKT 2504
S YDS+ES+ S D++DD SD +QEH + NSYSW+L+ L MV+L L+N+K
Sbjct: 2470 DSGVIYDSDESIHS-----DEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNVKN 2524
Query: 2505 FYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTAEESLSAG 2564
F+P AG + +ELPV+SPL AV+K L+ WEQ+L +++ GPP NYI ++ + S+ AG
Sbjct: 2525 FFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAG 2584
Query: 2565 PAILRHKALLEPTNTPFKSKHHLALSVKRLWQYLVKQEEIQETFIKNIFTKKRCLNEIEA 2624
PAILR+KA+LEP NTPFKS+ A VKRLW +LVKQE +QETFI+ IFTKKR +E+EA
Sbjct: 2585 PAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEA 2644
Query: 2625 DLGYPGGKARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQVYTWVDDD 2684
DLGYPGGKA++IHKESD+I AF+VNKAN N I +AS+HDVQELDV+ +LA Q Y W+ ++
Sbjct: 2645 DLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEE 2704
Query: 2685 IEVETKGSEDFLVIHARDDLTAV--QGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKK 2742
+ E+K S+D + R T + T Y+ S P ++PWLG+ QT GASV++K+
Sbjct: 2705 YDRESKSSDD---VDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMKR 2761
Query: 2743 AINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKF 2802
++NV+RMTSHP YYLTGAQDGSVRMFEW QQ+ CFR GN+RVTR+ FN QGNK
Sbjct: 2762 NLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKC 2821
Query: 2803 GIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDN 2862
G+ D +G+LS++Q N T S PKPY++WQCH+K +DF F++SSSL+AT+G S DN
Sbjct: 2822 GVADGEGFLSIWQVN-----QTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDN 2876
Query: 2863 RNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQ 2922
RNVCLWDTL++P NSL+H FTCHD GATVL YAPK QLLISGGRKG +FD+ QRQ
Sbjct: 2877 RNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIH 2936
Query: 2923 LFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTG 2982
FQ+HDS +KA+A+DP EEYF TGSAEGNIK+W L+ GL+H+F SEHA+QSIFRNIG G
Sbjct: 2937 TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAG 2996
Query: 2983 VMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVL 3019
VMQI+ N +FSCGADGT+K R+LP+ F+ N +L
Sbjct: 2997 VMQIDIIQGNRLFSCGADGTLKTRVLPNAFNIPNRIL 3033
>gi|19913369 transducin beta-like 3 [Homo sapiens]
Length = 808
Score = 57.0 bits (136), Expect = 3e-07
Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 9/122 (7%)
Query: 2884 CHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYF 2943
CHD +A AP +LL +G + ++ L Q Q +F H + V P ++
Sbjct: 477 CHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVL 536
Query: 2944 VTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGADGTM 3003
T SA+G IK+W+L F L TF A + G + S G+DG +
Sbjct: 537 ATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRG---------TQLLSSGSDGLV 587
Query: 3004 KM 3005
K+
Sbjct: 588 KL 589
Score = 49.3 bits (116), Expect = 6e-05
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 2833 TWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVL 2892
T +CH+K N + L+AT + +R LW P L+ F+ H G +
Sbjct: 474 TQRCHDKDINSVAIAPNDKLLATG---SQDRTAKLW---ALPQCQLLGVFSGHRRGLWCV 527
Query: 2893 AYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNI 2952
++P Q+L + G ++ L + F+ HD+ V VA ++ ++G +
Sbjct: 528 QFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLV 587
Query: 2953 KIWSL 2957
K+W++
Sbjct: 588 KLWTI 592
Score = 38.5 bits (88), Expect = 0.10
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 10/99 (10%)
Query: 2877 SLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDL--CQRQQR-QLFQS------- 2926
S + T H S T LA++ ++S GR ++DL CQ + +F+S
Sbjct: 186 SCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLL 245
Query: 2927 HDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHT 2965
+ PV + V YF+T +G +++W ++ ++T
Sbjct: 246 PEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYT 284
Score = 37.0 bits (84), Expect = 0.30
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 2885 HDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAV--DPTEEY 2942
H + +A+ P LL +GG G V+D+ + F+ V VA DPT
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167
Query: 2943 FVTGSAEGNIKIWSLSTFGLLHTFVSEHA 2971
+ + + I++WSL L + ++
Sbjct: 168 LFSSATDAAIRVWSLQDRSCLAVLTAHYS 196
Score = 35.0 bits (79), Expect = 1.1
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Query: 2890 TVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQS-HDSPVKAVAVDPTEEYFVTGSA 2948
T +P +++L++ R + + +L+++ H +PV +A DPT TG
Sbjct: 70 TAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGC 129
Query: 2949 EGNIKIWSL 2957
+G +++W +
Sbjct: 130 DGAVRVWDI 138
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 54.7 bits (130), Expect = 1e-06
Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 2/122 (1%)
Query: 2878 LVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVD 2937
L+H H L ++P QLL++ G+ ++D+ H S V VA
Sbjct: 182 LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFC 241
Query: 2938 PTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPAN--HIF 2995
P + +FV+ S++ ++K+W + T +HTF + + G G + G HI+
Sbjct: 242 PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Query: 2996 SC 2997
C
Sbjct: 302 DC 303
Score = 45.1 bits (105), Expect = 0.001
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 2892 LAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGN 2951
+AY+P + L SG G +FD+ + + H P++++ P + VT S +G
Sbjct: 154 IAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGY 213
Query: 2952 IKIWSLSTFGLLHTFVSEHA 2971
IKI+ + L T +S HA
Sbjct: 214 IKIYDVQHANLAGT-LSGHA 232
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 53.5 bits (127), Expect = 3e-06
Identities = 47/174 (27%), Positives = 70/174 (40%), Gaps = 28/174 (16%)
Query: 2812 SLYQ-TNWKCCP---------VTGSMPKPYLTWQCHNKT-----------ANDFVFVSSS 2850
SLY+ T+W C V+ S K W NK AN F S
Sbjct: 139 SLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSG 198
Query: 2851 SLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFT 2910
+ IA+AG ++ V +WD V N L+ + H G +++ P LI+ G
Sbjct: 199 TCIASAG---SDQTVKVWDVRV---NKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTL 252
Query: 2911 YVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLH 2964
+ DL + + Q H PV V+ E F +G A+ + +W + F LH
Sbjct: 253 KILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWR-TNFDELH 305
Score = 43.9 bits (102), Expect = 0.002
Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Query: 2846 FVSSSSLIATAGLSTDNRNVCL--WDTLVAPANSLVHA----FTCHDSGATVLAYAPKHQ 2899
F + I + LS + + + WDT + N HA + H T + ++P
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 2900 LLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSL 2957
LL S R ++ +R + F++H +PV++V ++ T S + +IK+WS+
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
Score = 42.0 bits (97), Expect = 0.009
Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 3/106 (2%)
Query: 2860 TDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQ 2919
++++ + +WDT V+ F+ A + + P + S G V+D+ +
Sbjct: 163 SEDKTIKIWDTT---NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNK 219
Query: 2920 QRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHT 2965
Q +Q H V ++ P+ Y +T S++G +KI L L++T
Sbjct: 220 LLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYT 265
Score = 32.7 bits (73), Expect = 5.6
Identities = 38/235 (16%), Positives = 86/235 (36%), Gaps = 27/235 (11%)
Query: 2773 WGHSQQITCFRSGGNSRV-TRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPY 2831
W +R G+ V T ++F+ GN D + L+ + + +
Sbjct: 45 WNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKR---------GKF 95
Query: 2832 LTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATV 2891
++ H F + +ATA ++++++ +W +++ H
Sbjct: 96 SEFKAHTAPVRSVDFSADGQFLATA---SEDKSIKVWSMY---RQRFLYSLYRHTHWVRC 149
Query: 2892 LAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGN 2951
++P +L++S ++D +Q F V +P+ + ++
Sbjct: 150 AKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQT 209
Query: 2952 IKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPA-NHIFSCGADGTMKM 3005
+K+W + LL + GV I P+ N++ + +DGT+K+
Sbjct: 210 VKVWDVRVNKLLQHYQVHSG----------GVNCISFHPSGNYLITASSDGTLKI 254
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 52.4 bits (124), Expect = 7e-06
Identities = 46/206 (22%), Positives = 91/206 (44%), Gaps = 18/206 (8%)
Query: 2761 TGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKC 2820
+G++D +VR++ + T FR+ + V + F G F D + ++ T+ +
Sbjct: 40 SGSRDKTVRIWVPNVKGESTVFRAH-TATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 98
Query: 2821 CPVTGSMPKPYLTW-QCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLV 2879
+ S ++ W +C + + + VS+S D++ V LWD + V
Sbjct: 99 FLFSLSQ---HINWVRCAKFSPDGRLIVSAS----------DDKTVKLWDK---SSRECV 142
Query: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPT 2939
H++ H T + + P + + G V+D+ + Q +Q H + V ++ P+
Sbjct: 143 HSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPS 202
Query: 2940 EEYFVTGSAEGNIKIWSLSTFGLLHT 2965
Y +T S++ +KI L LL+T
Sbjct: 203 GNYLITASSDSTLKILDLMEGRLLYT 228
Score = 41.2 bits (95), Expect = 0.016
Identities = 21/80 (26%), Positives = 40/80 (50%)
Query: 2877 SLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAV 2936
S + FT H T + ++P LL SG R ++ + + +F++H + V++V
Sbjct: 14 SRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHF 73
Query: 2937 DPTEEYFVTGSAEGNIKIWS 2956
+ FVT S + +K+W+
Sbjct: 74 CSDGQSFVTASDDKTVKVWA 93
Score = 37.0 bits (84), Expect = 0.30
Identities = 43/234 (18%), Positives = 85/234 (36%), Gaps = 25/234 (10%)
Query: 2773 WGHSQQITCFR-SGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPY 2831
W Q +R +G VT + F+ G+ D + ++ N K
Sbjct: 8 WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK---------GES 58
Query: 2832 LTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATV 2891
++ H T F S TA +D++ V +W T + + + H +
Sbjct: 59 TVFRAHTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFLFSLSQHINWVRC 112
Query: 2892 LAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGN 2951
++P +L++S ++D R+ + H V V P+ +
Sbjct: 113 AKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNT 172
Query: 2952 IKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGADGTMKM 3005
+K+W + T LL + A + G+ +G N++ + +D T+K+
Sbjct: 173 VKVWDVRTHRLLQHYQLHSAAVN-------GLSFHPSG--NYLITASSDSTLKI 217
Score = 33.1 bits (74), Expect = 4.3
Identities = 38/159 (23%), Positives = 59/159 (37%), Gaps = 49/159 (30%)
Query: 101 WQKSGQFFLESIAHNITW------DPTGSRLLTGSS--YLQLWSNTNLEKPTEDENLNKT 152
W Q FL S++ +I W P G +++ S ++LW ++ E
Sbjct: 92 WATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRE----------- 140
Query: 153 DLNFGDWKCIW-HCKTASQVHLMKFSPDGEFFATAGKDDCLLKVWYNVENWRTAVTSPDG 211
C+ +C+ V + F P G A AG D+ +KVW D
Sbjct: 141 --------CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDN-TVKVW-------------DV 178
Query: 212 SSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRAS 250
+ + Q Y H AVNG S+ + Y+ AS
Sbjct: 179 RTHRLLQH-------YQLHSAAVNGLSFHPSGNYLITAS 210
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 52.4 bits (124), Expect = 7e-06
Identities = 46/206 (22%), Positives = 91/206 (44%), Gaps = 18/206 (8%)
Query: 2761 TGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKC 2820
+G++D +VR++ + T FR+ + V + F G F D + ++ T+ +
Sbjct: 78 SGSRDKTVRIWVPNVKGESTVFRAH-TATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136
Query: 2821 CPVTGSMPKPYLTW-QCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLV 2879
+ S ++ W +C + + + VS+S D++ V LWD + V
Sbjct: 137 FLFSLSQ---HINWVRCAKFSPDGRLIVSAS----------DDKTVKLWDK---SSRECV 180
Query: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPT 2939
H++ H T + + P + + G V+D+ + Q +Q H + V ++ P+
Sbjct: 181 HSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPS 240
Query: 2940 EEYFVTGSAEGNIKIWSLSTFGLLHT 2965
Y +T S++ +KI L LL+T
Sbjct: 241 GNYLITASSDSTLKILDLMEGRLLYT 266
Score = 43.9 bits (102), Expect = 0.002
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 2853 IATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYV 2912
I T L++ + + CL + P S + FT H T + ++P LL SG R +
Sbjct: 29 INTKQLASGSMDSCLMVWHMKP-QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 87
Query: 2913 FDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWS 2956
+ + + +F++H + V++V + FVT S + +K+W+
Sbjct: 88 WVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWA 131
Score = 37.4 bits (85), Expect = 0.23
Identities = 45/246 (18%), Positives = 91/246 (36%), Gaps = 27/246 (10%)
Query: 2761 TGAQDGSVRMFEWGHSQQITCFR-SGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWK 2819
+G+ D + + W Q +R +G VT + F+ G+ D + ++ N K
Sbjct: 36 SGSMDSCLMV--WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93
Query: 2820 CCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLV 2879
++ H T F S TA +D++ V +W T +
Sbjct: 94 ---------GESTVFRAHTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFL 138
Query: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPT 2939
+ + H + ++P +L++S ++D R+ + H V V P+
Sbjct: 139 FSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPS 198
Query: 2940 EEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGA 2999
+ +K+W + T LL + A + G+ +G N++ + +
Sbjct: 199 GTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVN-------GLSFHPSG--NYLITASS 249
Query: 3000 DGTMKM 3005
D T+K+
Sbjct: 250 DSTLKI 255
Score = 33.1 bits (74), Expect = 4.3
Identities = 38/159 (23%), Positives = 59/159 (37%), Gaps = 49/159 (30%)
Query: 101 WQKSGQFFLESIAHNITW------DPTGSRLLTGSS--YLQLWSNTNLEKPTEDENLNKT 152
W Q FL S++ +I W P G +++ S ++LW ++ E
Sbjct: 130 WATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRE----------- 178
Query: 153 DLNFGDWKCIW-HCKTASQVHLMKFSPDGEFFATAGKDDCLLKVWYNVENWRTAVTSPDG 211
C+ +C+ V + F P G A AG D+ +KVW D
Sbjct: 179 --------CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDN-TVKVW-------------DV 216
Query: 212 SSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRAS 250
+ + Q Y H AVNG S+ + Y+ AS
Sbjct: 217 RTHRLLQH-------YQLHSAAVNGLSFHPSGNYLITAS 248
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 52.4 bits (124), Expect = 7e-06
Identities = 46/206 (22%), Positives = 91/206 (44%), Gaps = 18/206 (8%)
Query: 2761 TGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKC 2820
+G++D +VR++ + T FR+ + V + F G F D + ++ T+ +
Sbjct: 78 SGSRDKTVRIWVPNVKGESTVFRAH-TATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136
Query: 2821 CPVTGSMPKPYLTW-QCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLV 2879
+ S ++ W +C + + + VS+S D++ V LWD + V
Sbjct: 137 FLFSLSQ---HINWVRCAKFSPDGRLIVSAS----------DDKTVKLWDK---SSRECV 180
Query: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPT 2939
H++ H T + + P + + G V+D+ + Q +Q H + V ++ P+
Sbjct: 181 HSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPS 240
Query: 2940 EEYFVTGSAEGNIKIWSLSTFGLLHT 2965
Y +T S++ +KI L LL+T
Sbjct: 241 GNYLITASSDSTLKILDLMEGRLLYT 266
Score = 43.9 bits (102), Expect = 0.002
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 2853 IATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYV 2912
I T L++ + + CL + P S + FT H T + ++P LL SG R +
Sbjct: 29 INTKQLASGSMDSCLMVWHMKP-QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 87
Query: 2913 FDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWS 2956
+ + + +F++H + V++V + FVT S + +K+W+
Sbjct: 88 WVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWA 131
Score = 37.4 bits (85), Expect = 0.23
Identities = 45/246 (18%), Positives = 91/246 (36%), Gaps = 27/246 (10%)
Query: 2761 TGAQDGSVRMFEWGHSQQITCFR-SGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWK 2819
+G+ D + + W Q +R +G VT + F+ G+ D + ++ N K
Sbjct: 36 SGSMDSCLMV--WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93
Query: 2820 CCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLV 2879
++ H T F S TA +D++ V +W T +
Sbjct: 94 ---------GESTVFRAHTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFL 138
Query: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPT 2939
+ + H + ++P +L++S ++D R+ + H V V P+
Sbjct: 139 FSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPS 198
Query: 2940 EEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGA 2999
+ +K+W + T LL + A + G+ +G N++ + +
Sbjct: 199 GTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVN-------GLSFHPSG--NYLITASS 249
Query: 3000 DGTMKM 3005
D T+K+
Sbjct: 250 DSTLKI 255
Score = 33.1 bits (74), Expect = 4.3
Identities = 38/159 (23%), Positives = 59/159 (37%), Gaps = 49/159 (30%)
Query: 101 WQKSGQFFLESIAHNITW------DPTGSRLLTGSS--YLQLWSNTNLEKPTEDENLNKT 152
W Q FL S++ +I W P G +++ S ++LW ++ E
Sbjct: 130 WATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRE----------- 178
Query: 153 DLNFGDWKCIW-HCKTASQVHLMKFSPDGEFFATAGKDDCLLKVWYNVENWRTAVTSPDG 211
C+ +C+ V + F P G A AG D+ +KVW D
Sbjct: 179 --------CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDN-TVKVW-------------DV 216
Query: 212 SSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRAS 250
+ + Q Y H AVNG S+ + Y+ AS
Sbjct: 217 RTHRLLQH-------YQLHSAAVNGLSFHPSGNYLITAS 248
>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
Length = 2627
Score = 48.9 bits (115), Expect = 8e-05
Identities = 36/111 (32%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
Query: 2846 FVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAF-TCHDSGATVLAYAPKHQLLISG 2904
F + +AT G +R++ WD L+H+F CH T A+ K LLIS
Sbjct: 2069 FSTDGGSLATGGR---DRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWT-KDNLLISC 2124
Query: 2905 GRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIW 2955
G ++D Q+ F H S V AVA EE+ V+ S +G +K+W
Sbjct: 2125 SSDGSVGLWDPESGQRLGQFLGHQSAVSAVAA--VEEHVVSVSRDGTLKVW 2173
Score = 34.3 bits (77), Expect = 1.9
Identities = 16/58 (27%), Positives = 29/58 (50%)
Query: 2900 LLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSL 2957
L+++ G G T ++ Q H PV+A AV T +T S +G++++W +
Sbjct: 2210 LVVTVGLDGATRLWHPLLVCQTHTLLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQV 2267
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [Homo
sapiens]
Length = 340
Score = 48.9 bits (115), Expect = 8e-05
Identities = 35/155 (22%), Positives = 63/155 (40%), Gaps = 15/155 (9%)
Query: 2846 FVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGG 2905
F+ + ++ ++G +T LWD + FT H L+ AP +L +SG
Sbjct: 151 FLDDNQIVTSSGDTT----CALWDIETGQQTT---TFTGHTGDVMSLSLAPDTRLFVSGA 203
Query: 2906 RKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHT 2965
++D+ + RQ F H+S + A+ P F TGS + +++ L L T
Sbjct: 204 CDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMT 263
Query: 2966 FVSEHARQSIFRNIGTGVMQIETGPANHIFSCGAD 3000
+ + NI G+ + + + G D
Sbjct: 264 YSHD--------NIICGITSVSFSKSGRLLLAGYD 290
Score = 33.1 bits (74), Expect = 4.3
Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 4/124 (3%)
Query: 2833 TWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVL 2892
T+ H N F + + AT +D+ L+D L A + ++ G T +
Sbjct: 221 TFTGHESDINAICFFPNGNAFATG---SDDATCRLFD-LRADQELMTYSHDNIICGITSV 276
Query: 2893 AYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNI 2952
+++ +LL++G V+D + + + HD+ V + V TGS + +
Sbjct: 277 SFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFL 336
Query: 2953 KIWS 2956
KIW+
Sbjct: 337 KIWN 340
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 47.4 bits (111), Expect = 2e-04
Identities = 48/204 (23%), Positives = 80/204 (39%), Gaps = 20/204 (9%)
Query: 2754 PTLPYYLTGAQDGSVRMFEWGHSQQITCF--RSGGNSRVTRMRFNYQGNKFGIVDADGYL 2811
P Y L+ ++DG+VR++ Q TC G N V +F+ G F D
Sbjct: 553 PDRNYLLSSSEDGTVRLWSL---QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVA 609
Query: 2812 SLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTL 2871
L+ T+ +P + H N F +S+ +AT +R V LWD L
Sbjct: 610 RLWATDHY---------QPLRIFAGHLADVNCTRFHPNSNYVATGSA---DRTVRLWDVL 657
Query: 2872 VAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPV 2931
+ V FT H L ++P + L +G G ++D+ + H V
Sbjct: 658 ---NGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTV 714
Query: 2932 KAVAVDPTEEYFVTGSAEGNIKIW 2955
++ E +GS + +++W
Sbjct: 715 CSLRFSRDGEILASGSMDNTVRLW 738
Score = 37.0 bits (84), Expect = 0.30
Identities = 14/52 (26%), Positives = 25/52 (48%)
Query: 2912 VFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLL 2963
+ D + ++ H PV + P Y ++ S +G +++WSL TF L
Sbjct: 527 IMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCL 578
Score = 36.2 bits (82), Expect = 0.51
Identities = 23/105 (21%), Positives = 41/105 (39%), Gaps = 15/105 (14%)
Query: 2859 STDNRNVCLWDTLVAPANSLVHAFTC------HDSGATVLAYAPKHQLLISGGRKGFTYV 2912
S+++ V LW + FTC H+ ++P +SGG +
Sbjct: 561 SSEDGTVRLWS---------LQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARL 611
Query: 2913 FDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSL 2957
+ Q ++F H + V P Y TGSA+ +++W +
Sbjct: 612 WATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV 656
Score = 34.7 bits (78), Expect = 1.5
Identities = 13/76 (17%), Positives = 31/76 (40%)
Query: 2882 FTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEE 2941
F H + + P + +G ++D+ ++F H P+ ++ P
Sbjct: 623 FAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGR 682
Query: 2942 YFVTGSAEGNIKIWSL 2957
+ TG+ +G + +W +
Sbjct: 683 FLATGATDGRVLLWDI 698
>gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens]
Length = 606
Score = 47.0 bits (110), Expect = 3e-04
Identities = 78/298 (26%), Positives = 123/298 (41%), Gaps = 50/298 (16%)
Query: 2742 KAINNVRRMTSHPTLPYYL-TGAQDGSVRMFEWGHSQQITCFRSGGNSR-VTRMRFNYQG 2799
K IN+V S P Y L TG+ D FE G + F G +SR V +RF+ G
Sbjct: 147 KVINSVDIKQSRP---YRLATGSDDNCAAFFE-GPPFKFK-FTIGDHSRFVNCVRFSPDG 201
Query: 2800 NKFGIVDADGYLSLY--QTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAG 2857
N+F ADG + +Y +T K C + GS K + ++ S S +T
Sbjct: 202 NRFATASADGQIYIYDGKTGEKVCALGGS------------KAHDGGIYAISWSPDSTHL 249
Query: 2858 LS-TDNRNVCLWDTLVAPANSLVHAFTCHDSGATVL------AYAPKHQLLISGGRKGFT 2910
LS + ++ +WD V NS+V F G+TVL + H L+S G+
Sbjct: 250 LSASGDKTSKIWDVSV---NSVVSTF---PMGSTVLDQQLGCLWQKDH--LLSVSLSGYI 301
Query: 2911 YVFDLCQ-RQQRQLFQSHDSPVKAVAVDPT--EEYFVTGSAEGNIKIWSLSTFGLLHTFV 2967
D + + + H ++ + V + Y +GS +G+I W T G +F
Sbjct: 302 NYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSET-GENDSFA 360
Query: 2968 SE-HARQSIFRNIGTGVMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVLKNDVK 3024
+ H Q V ++ + + SC D T++ L + V+K DV+
Sbjct: 361 GKGHTNQ---------VSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQ 409
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 46.2 bits (108), Expect = 5e-04
Identities = 32/127 (25%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Query: 2837 HNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANS-LVHAFTCHDSGATVLAYA 2895
H ++ D + + + + A S D ++ +WD AP+ + ++ T HD V++++
Sbjct: 260 HTRSVEDLQWSPTENTVF-ASCSAD-ASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS 317
Query: 2896 PKHQLLISGGRKGFTYVFDLCQRQQRQ---LFQSHDSPVKAVAVDPTEE-YFVTGSAEGN 2951
+ L+SGG G ++DL Q + F+ H +PV +V P + F A+
Sbjct: 318 RREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQ 377
Query: 2952 IKIWSLS 2958
I W L+
Sbjct: 378 ITQWDLA 384
>gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [Homo
sapiens]
Length = 340
Score = 45.4 bits (106), Expect = 8e-04
Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Query: 2846 FVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGG 2905
F+ ++++ ++G +T LWD ++ F H LA +P L ISG
Sbjct: 151 FLDDNNIVTSSGDTT----CALWDIETGQQKTV---FVGHTGDCMSLAVSPDFNLFISGA 203
Query: 2906 RKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSL 2957
++D+ + RQ F H+S + A+ P E TGS + + +++ L
Sbjct: 204 CDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDL 255
Score = 33.5 bits (75), Expect = 3.3
Identities = 14/60 (23%), Positives = 29/60 (48%)
Query: 2912 VFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHA 2971
++D+ QQ+ +F H ++AV P F++G+ + + K+W + TF +
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227
Score = 32.3 bits (72), Expect = 7.3
Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 2833 TWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVL 2892
T+ H N F + I T +D+ + L+D L A + + G T +
Sbjct: 221 TFTGHESDINAICFFPNGEAICTG---SDDASCRLFD-LRADQELICFSHESIICGITSV 276
Query: 2893 AYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNI 2952
A++ +LL +G V+D + ++ + HD+ V + V TGS + +
Sbjct: 277 AFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFL 336
Query: 2953 KIWS 2956
KIW+
Sbjct: 337 KIWN 340
>gi|18874090 WD repeat domain 48 [Homo sapiens]
Length = 677
Score = 45.4 bits (106), Expect = 8e-04
Identities = 47/214 (21%), Positives = 88/214 (41%), Gaps = 40/214 (18%)
Query: 2814 YQTNWK-----CCP----VTGSMPKPYLTWQCHN-------KTANDFV----FVSSSSLI 2853
+ T+W CC ++ S W H +T D+V + L+
Sbjct: 73 HHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV 132
Query: 2854 ATAGLSTDNRNVCLWD----TLVAPANSLVHAFTCHDSGATVLAYAPKH--QLLISGGRK 2907
A+AGL +R + LWD T + +N+ V + + ++ + A +++SG +
Sbjct: 133 ASAGL---DRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTE 189
Query: 2908 GFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFV 2967
V+D + + H VKA+ ++ ++GS++G I++WSL + T
Sbjct: 190 KVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIAT-- 247
Query: 2968 SEHARQSIFRNIGTGVMQIETGPA-NHIFSCGAD 3000
+R GV ++ A H++S G D
Sbjct: 248 --------YRVHDEGVWALQVNDAFTHVYSGGRD 273
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 45.1 bits (105), Expect = 0.001
Identities = 46/213 (21%), Positives = 81/213 (38%), Gaps = 22/213 (10%)
Query: 2758 YYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSL---Y 2814
+ +TGA D +R+F + +++ F + +S R + F + +D L +
Sbjct: 71 WVVTGADDMQIRVFNYNTLERVHMFEA--HSDYIRCIAVHPTQPFILTSSDDMLIKLWDW 128
Query: 2815 QTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAP 2874
W C V + + K N F +S+SL +R + +W +
Sbjct: 129 DKKWSCSQVFEGHTHYVMQIVINPKDNNQF---ASASL---------DRTIKVWQLGSSS 176
Query: 2875 ANSLVHAFTCHDSGATVLAY--APKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVK 2932
N + H+ G + Y LISG ++D + Q + H V
Sbjct: 177 PNFTLEG---HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVS 233
Query: 2933 AVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHT 2965
+ P +TGS +G ++IW ST+ L T
Sbjct: 234 CASFHPELPIIITGSEDGTVRIWHSSTYRLEST 266
Score = 44.7 bits (104), Expect = 0.001
Identities = 33/146 (22%), Positives = 62/146 (42%), Gaps = 14/146 (9%)
Query: 2862 NRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQR 2921
N +VC+W+ +LV F D + + +++G VF+ ++
Sbjct: 36 NGSVCVWNH---ETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERV 92
Query: 2922 QLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGT 2981
+F++H ++ +AV PT+ + +T S + IK+W + + + +F
Sbjct: 93 HMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWD---------WDKKWSCSQVFEGHTH 143
Query: 2982 GVMQIETGPA--NHIFSCGADGTMKM 3005
VMQI P N S D T+K+
Sbjct: 144 YVMQIVINPKDNNQFASASLDRTIKV 169
Score = 40.4 bits (93), Expect = 0.027
Identities = 36/166 (21%), Positives = 65/166 (39%), Gaps = 20/166 (12%)
Query: 2747 VRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFN-YQGNKFGIV 2805
+R + HPT P+ LT + D +++++W + G V ++ N N+F
Sbjct: 102 IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASA 161
Query: 2806 DADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSS---LIATAGLSTDN 2862
D + ++Q P T + H K N + S LI+ A D+
Sbjct: 162 SLDRTIKVWQL---------GSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGA----DD 208
Query: 2863 RNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKG 2908
R V +WD + V H + ++ P+ ++I+G G
Sbjct: 209 RLVKIWD---YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDG 251
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 45.1 bits (105), Expect = 0.001
Identities = 46/239 (19%), Positives = 89/239 (37%), Gaps = 40/239 (16%)
Query: 2750 MTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKF------- 2802
++ +P TG+ D + ++++ + +++ R G ++ + + FN G++
Sbjct: 183 LSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLR-GHSAEIISLSFNTSGDRIITGSFDH 241
Query: 2803 --GIVDAD------------GYLSLYQTNWKCCPV-TGSMPKPYLTWQC----------- 2836
+ DAD +S NW C + TGSM K W
Sbjct: 242 TVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTG 301
Query: 2837 HNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAP 2896
H+ D F + LIATA R A + H+ + +++ P
Sbjct: 302 HDDEILDSCFDYTGKLIATASADGTAR------IFSAATRKCIAKLEGHEGEISKISFNP 355
Query: 2897 KHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIW 2955
+ L++G ++D Q Q+ + H + + A + +TGS + +IW
Sbjct: 356 QGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 34.7 bits (78), Expect = 1.5
Identities = 14/80 (17%), Positives = 38/80 (47%)
Query: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPT 2939
H F H + L++ P+ L+ +G ++D+ ++ + H + + +++ + +
Sbjct: 171 HTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTS 230
Query: 2940 EEYFVTGSAEGNIKIWSLST 2959
+ +TGS + + +W T
Sbjct: 231 GDRIITGSFDHTVVVWDADT 250
Score = 32.0 bits (71), Expect = 9.6
Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 1/90 (1%)
Query: 2878 LVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVD 2937
L H T +A I+G ++D ++ + H + V A+A +
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 2938 -PTEEYFVTGSAEGNIKIWSLSTFGLLHTF 2966
P + TGS + K+WS+ T HTF
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTF 173
>gi|148536855 coatomer protein complex, subunit alpha isoform 1 [Homo
sapiens]
Length = 1233
Score = 45.1 bits (105), Expect = 0.001
Identities = 46/262 (17%), Positives = 98/262 (37%), Gaps = 42/262 (16%)
Query: 2744 INNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFG 2803
++ +R H P+ L+ + D ++R++ W S+ C +G N V +F+ +
Sbjct: 93 LDYIRTTFFHHEYPWILSASDDQTIRVWNW-QSRTCVCVLTGHNHYVMCAQFHPTEDLV- 150
Query: 2804 IVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNR 2863
V+ S+ + W + ++ + +D R
Sbjct: 151 -------------------VSASLDQTVRVWDISGLRKKN---------LSPGAVESDVR 182
Query: 2864 NVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQL 2923
+ D + H HD G A+ P L++SG ++ + + + ++
Sbjct: 183 GITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEV 242
Query: 2924 --FQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGT 2981
+ H + V P +E ++ S + +I++W +S + TF +H R +
Sbjct: 243 DTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWV------ 296
Query: 2982 GVMQIETGPANHIFSCGADGTM 3003
+ P ++F+ G DG M
Sbjct: 297 ----LAAHPNLNLFAAGHDGGM 314
Score = 36.6 bits (83), Expect = 0.39
Identities = 20/89 (22%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 2892 LAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGN 2951
L++ PK +++ G ++D F HD PV+ + + FV+G +
Sbjct: 15 LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
Query: 2952 IKIWSLSTFGLLHTFVS--EHARQSIFRN 2978
IK+W+ L T + ++ R + F +
Sbjct: 75 IKVWNYKLRRCLFTLLGHLDYIRTTFFHH 103
>gi|148536853 coatomer protein complex, subunit alpha isoform 2 [Homo
sapiens]
Length = 1224
Score = 45.1 bits (105), Expect = 0.001
Identities = 46/262 (17%), Positives = 98/262 (37%), Gaps = 42/262 (16%)
Query: 2744 INNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFG 2803
++ +R H P+ L+ + D ++R++ W S+ C +G N V +F+ +
Sbjct: 93 LDYIRTTFFHHEYPWILSASDDQTIRVWNW-QSRTCVCVLTGHNHYVMCAQFHPTEDLV- 150
Query: 2804 IVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNR 2863
V+ S+ + W + ++ + +D R
Sbjct: 151 -------------------VSASLDQTVRVWDISGLRKKN---------LSPGAVESDVR 182
Query: 2864 NVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQL 2923
+ D + H HD G A+ P L++SG ++ + + + ++
Sbjct: 183 GITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEV 242
Query: 2924 --FQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGT 2981
+ H + V P +E ++ S + +I++W +S + TF +H R +
Sbjct: 243 DTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWV------ 296
Query: 2982 GVMQIETGPANHIFSCGADGTM 3003
+ P ++F+ G DG M
Sbjct: 297 ----LAAHPNLNLFAAGHDGGM 314
Score = 36.6 bits (83), Expect = 0.39
Identities = 20/89 (22%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 2892 LAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGN 2951
L++ PK +++ G ++D F HD PV+ + + FV+G +
Sbjct: 15 LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYK 74
Query: 2952 IKIWSLSTFGLLHTFVS--EHARQSIFRN 2978
IK+W+ L T + ++ R + F +
Sbjct: 75 IKVWNYKLRRCLFTLLGHLDYIRTTFFHH 103
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 45.1 bits (105), Expect = 0.001
Identities = 41/191 (21%), Positives = 77/191 (40%), Gaps = 15/191 (7%)
Query: 2779 ITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHN 2838
+ C G V+ ++F+ G AD + ++ G K T HN
Sbjct: 33 LKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGA------YDGKYEK---TLYGHN 83
Query: 2839 KTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKH 2898
+D + S SS + +A +D++ + LWD + + H + + P
Sbjct: 84 LEISDVAWSSDSSRLVSA---SDDKTLKLWDVR---SGKCLKTLKGHSNYVFCCNFNPPS 137
Query: 2899 QLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLS 2958
L+ISG ++++ + + +H PV AV + + V+GS +G +IW +
Sbjct: 138 NLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAA 197
Query: 2959 TFGLLHTFVSE 2969
+ L T V +
Sbjct: 198 SGQCLKTLVDD 208
Score = 39.7 bits (91), Expect = 0.046
Identities = 28/136 (20%), Positives = 56/136 (41%), Gaps = 6/136 (4%)
Query: 2862 NRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQ-Q 2920
+ V +W+ + + H + + + L++SG G ++D Q
Sbjct: 146 DETVKIWEV---KTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCL 202
Query: 2921 RQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVS-EHARQSIFRNI 2979
+ L + PV V P +Y +T + + +K+W S L T+ ++ + IF N
Sbjct: 203 KTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANF 262
Query: 2980 G-TGVMQIETGPANHI 2994
TG I +G +++
Sbjct: 263 SVTGGKWIVSGSEDNL 278
Score = 32.7 bits (73), Expect = 5.6
Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 2901 LISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGN--IKIW 2955
++SG Y+++L ++ Q Q H V + A PTE + + E + IK+W
Sbjct: 270 IVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLW 326
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [Homo
sapiens]
Length = 340
Score = 44.7 bits (104), Expect = 0.001
Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 7/112 (6%)
Query: 2846 FVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGG 2905
F+ S ++ ++G +T LWD A + FT H L+ +P + +SG
Sbjct: 151 FLDDSQIVTSSGDTT----CALWDIETAQQTT---TFTGHSGDVMSLSLSPDMRTFVSGA 203
Query: 2906 RKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSL 2957
+ ++D+ RQ F H S + AV+ P F TGS + +++ L
Sbjct: 204 CDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDL 255
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 44.7 bits (104), Expect = 0.001
Identities = 48/227 (21%), Positives = 83/227 (36%), Gaps = 34/227 (14%)
Query: 2753 HPTLPYYLTGAQDGSVRMFEWGHSQQIT----------CFRSGG-----NSRVTRMRFNY 2797
+P +G+ D + R+ W S+ T C R GG N VT + +N
Sbjct: 178 NPVSDLLASGSGDSTARI--WNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNS 235
Query: 2798 QGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAG 2857
+G DG+ ++ + G P + + K + I +AG
Sbjct: 236 EGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKK----------GNFILSAG 285
Query: 2858 LSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQ 2917
+ ++ +WD A F H + A + + + S +V L Q
Sbjct: 286 V---DKTTIIWDAHTGEAKQ---QFPFHSAPALDVDWQ-SNNTFASCSTDMCIHVCKLGQ 338
Query: 2918 RQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLH 2964
+ + FQ H + V A+ DPT + S + +KIWS+ +H
Sbjct: 339 DRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVH 385
Score = 41.6 bits (96), Expect = 0.012
Identities = 30/147 (20%), Positives = 61/147 (41%), Gaps = 15/147 (10%)
Query: 2829 KPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSG 2888
+P T+Q H N + + +L+A+ +D+ + +W ++ VH H+
Sbjct: 340 RPIKTFQGHTNEVNAIKWDPTGNLLASC---SDDMTLKIWSM---KQDNCVHDLQAHNKE 393
Query: 2889 ATVLAYAPK---------HQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPT 2939
+ ++P + +L S ++D+ + H PV +VA P
Sbjct: 394 IYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPD 453
Query: 2940 EEYFVTGSAEGNIKIWSLSTFGLLHTF 2966
Y +GS + + IW+ T L+H++
Sbjct: 454 GRYLASGSFDKCVHIWNTQTGALVHSY 480
>gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [Homo
sapiens]
Length = 514
Score = 44.7 bits (104), Expect = 0.001
Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 9/83 (10%)
Query: 2922 QLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGT 2981
++ H V+ +AV+P ++FVTGSA+ IKIW L+ S + S+ +I T
Sbjct: 198 RVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLA---------SGKLKLSLTGHIST 248
Query: 2982 GVMQIETGPANHIFSCGADGTMK 3004
I + + ++FSCG D +K
Sbjct: 249 VRGVIVSTRSPYLFSCGEDKQVK 271
Score = 40.4 bits (93), Expect = 0.027
Identities = 39/199 (19%), Positives = 71/199 (35%), Gaps = 27/199 (13%)
Query: 2823 VTGSMPKPYLTWQC-----------HNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTL 2871
VTGS + W H T + + S + + G +++ V WD
Sbjct: 220 VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCG---EDKQVKCWDL- 275
Query: 2872 VAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPV 2931
N ++ + H S L P +L++ R ++D+ + H + V
Sbjct: 276 --EYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAV 333
Query: 2932 KAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPA 2991
V E +TGS + I++W L G ++ H + V + P
Sbjct: 334 ATVRCQAAEPQIITGSHDTTIRLWDL-VAGKTRVTLTNHKK---------SVRAVVLHPR 383
Query: 2992 NHIFSCGADGTMKMRILPD 3010
++ F+ G+ +K PD
Sbjct: 384 HYTFASGSPDNIKQWKFPD 402
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 43.9 bits (102), Expect = 0.002
Identities = 45/216 (20%), Positives = 82/216 (37%), Gaps = 25/216 (11%)
Query: 2750 MTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADG 2809
M+ P ++TG D SV+ ++ F + T+ R + + + +D D
Sbjct: 502 MSLSPDQRGFVTGGADKSVKFWD---------FELVKDENSTQKRLSVKQTRTLQLDEDV 552
Query: 2810 YLSLYQTNWKCCPVT----------GSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLS 2859
Y N K V+ K +L+ H +LIAT
Sbjct: 553 LCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSA- 611
Query: 2860 TDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQ 2919
+RNV +W + + A HD L + PK L + G+ +D + +
Sbjct: 612 --DRNVKIWGLDFGDCHKSLFA---HDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFE 666
Query: 2920 QRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIW 2955
Q + H + +AV P+ +Y V+ S + ++++W
Sbjct: 667 HIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702
Score = 39.7 bits (91), Expect = 0.046
Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
Query: 2849 SSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKG 2908
SS IA + D+ + TL + TC A + P + ++ G + G
Sbjct: 424 SSDNIAVLSAAADSIKIWNRSTL-----QCIRTMTCEY--ALCSFFVPGDRQVVIGTKTG 476
Query: 2909 FTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIW 2955
++DL + +HD + ++++ P + FVTG A+ ++K W
Sbjct: 477 KLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFW 523
Score = 35.4 bits (80), Expect = 0.86
Identities = 30/120 (25%), Positives = 48/120 (40%), Gaps = 11/120 (9%)
Query: 2886 DSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVT 2945
D ++Y+P +LL +F + + H PV + + T
Sbjct: 549 DEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIAT 608
Query: 2946 GSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHI-FSCGADGTMK 3004
GSA+ N+KIW L FG H + H VM ++ P +H+ F+ G D +K
Sbjct: 609 GSADRNVKIWGLD-FGDCHKSLFAH---------DDSVMYLQFVPKSHLFFTAGKDHKIK 658
Score = 33.1 bits (74), Expect = 4.3
Identities = 21/127 (16%), Positives = 52/127 (40%), Gaps = 6/127 (4%)
Query: 2832 LTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATV 2891
+T+ H + +A+ TD + +WD + S ++ H T
Sbjct: 101 VTFNGHKAAITTLKYDQLGGRLASGSKDTD---IIVWDVI---NESGLYRLKGHKDAITQ 154
Query: 2892 LAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGN 2951
+ + LL++ G+ +DL + + H + V + + E+ +TG+++
Sbjct: 155 ALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSE 214
Query: 2952 IKIWSLS 2958
+++W ++
Sbjct: 215 LRVWDIA 221
>gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]
Length = 919
Score = 43.9 bits (102), Expect = 0.002
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
Query: 2860 TDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYA--PKHQLLISGGRKGFTYVFDLCQ 2917
+ ++ V WD V P+ V T H +G+ V + A P +LL +G ++D+
Sbjct: 773 SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 831
Query: 2918 RQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSL 2957
+ Q + H S V++V P Y +TGS + IK+ L
Sbjct: 832 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 871
>gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]
Length = 927
Score = 43.9 bits (102), Expect = 0.002
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
Query: 2860 TDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYA--PKHQLLISGGRKGFTYVFDLCQ 2917
+ ++ V WD V P+ V T H +G+ V + A P +LL +G ++D+
Sbjct: 781 SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 839
Query: 2918 RQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSL 2957
+ Q + H S V++V P Y +TGS + IK+ L
Sbjct: 840 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 879
>gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]
Length = 920
Score = 43.9 bits (102), Expect = 0.002
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
Query: 2860 TDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYA--PKHQLLISGGRKGFTYVFDLCQ 2917
+ ++ V WD V P+ V T H +G+ V + A P +LL +G ++D+
Sbjct: 774 SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 832
Query: 2918 RQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSL 2957
+ Q + H S V++V P Y +TGS + IK+ L
Sbjct: 833 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 872
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 43.5 bits (101), Expect = 0.003
Identities = 26/110 (23%), Positives = 42/110 (38%), Gaps = 3/110 (2%)
Query: 2860 TDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQ 2919
+ + N+ LWD V + H L ++P + L S ++DL +
Sbjct: 124 SQDTNIKLWDIR---RKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
Query: 2920 QRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSE 2969
F H PV V P E +GS++ I+ W L F ++ E
Sbjct: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGE 230
Score = 42.4 bits (98), Expect = 0.007
Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 6/119 (5%)
Query: 2848 SSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRK 2907
+S L+AT G D+ V LW + N ++ + T H S + +L+++G +
Sbjct: 31 ASGRLLATGG---DDCRVNLWS--INKPNCIM-SLTGHTSPVESVRLNTPEELIVAGSQS 84
Query: 2908 GFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTF 2966
G V+DL + + H + + ++ P E+ +GS + NIK+W + G + +
Sbjct: 85 GSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY 143
Score = 40.0 bits (92), Expect = 0.035
Identities = 21/73 (28%), Positives = 36/73 (49%)
Query: 2899 QLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLS 2958
+LL +GG ++ + + H SPV++V ++ EE V GS G+I++W L
Sbjct: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE 93
Query: 2959 TFGLLHTFVSEHA 2971
+L T + A
Sbjct: 94 AAKILRTLMGHKA 106
Score = 39.7 bits (91), Expect = 0.046
Identities = 38/179 (21%), Positives = 69/179 (38%), Gaps = 16/179 (8%)
Query: 2760 LTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWK 2819
+ G+Q GS+R+++ + +I G + + + F+ G D + L+ K
Sbjct: 79 VAGSQSGSIRVWDL-EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 2820 CCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLV 2879
C ++ H++ F +A+A D+ V LWD A ++
Sbjct: 138 GC---------VFRYRGHSQAVRCLRFSPDGKWLASAA---DDHTVKLWDLT---AGKMM 182
Query: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDP 2938
F H V+ + P LL SG +DL + Q + PV++V +P
Sbjct: 183 SEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 43.5 bits (101), Expect = 0.003
Identities = 36/167 (21%), Positives = 68/167 (40%), Gaps = 17/167 (10%)
Query: 2795 FNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIA 2854
F+ G + AD L +++ TG + L + H F + IA
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAE------TG---EKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 2855 TAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAY--APKHQLLISGGRKGFTYV 2912
T + ++ V +W+++ LVH + H + + H LL +G F +
Sbjct: 674 TCSV---DKKVKIWNSMTG---ELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKL 727
Query: 2913 FDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLST 2959
+DL Q++ R H + V P ++ + SA+G +K+W ++
Sbjct: 728 WDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Score = 40.8 bits (94), Expect = 0.021
Identities = 47/218 (21%), Positives = 83/218 (38%), Gaps = 32/218 (14%)
Query: 2754 PTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSL 2813
P L Y G ++G++ + E +++ F+S + T + ++ ++ + +
Sbjct: 928 PHLQYIAFGDENGAIEILELVNNR---IFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 984
Query: 2814 YQTNW---KCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDT 2870
NW KC + G H +T DF + +S L++ + T V +W+
Sbjct: 985 QVWNWQLDKCIFLRG-----------HQETVKDFRLLKNSRLLSWSFDGT----VKVWNI 1029
Query: 2871 LVAPANSLVHAFTCHDSGATVLAYAPKHQLL----ISGGRKGFTYVFDLCQRQQRQLFQS 2926
+ F CH TVL+ H S + + FDL +
Sbjct: 1030 ITGNKEK---DFVCHQG--TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHE--LRG 1082
Query: 2927 HDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLH 2964
H+ V+ A TG G I+IW++S LLH
Sbjct: 1083 HNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1120
Score = 33.1 bits (74), Expect = 4.3
Identities = 21/89 (23%), Positives = 37/89 (41%), Gaps = 1/89 (1%)
Query: 2885 HDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFV 2944
H ++ Q + S G VF ++ ++H+ V A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 2945 TGSAEGNIKIWSLSTFGLLHTFVSEHARQ 2973
T S + +KIW+ T L+HT+ EH+ Q
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY-DEHSEQ 701
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 43.5 bits (101), Expect = 0.003
Identities = 36/167 (21%), Positives = 68/167 (40%), Gaps = 17/167 (10%)
Query: 2795 FNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIA 2854
F+ G + AD L +++ TG + L + H F + IA
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAE------TG---EKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 2855 TAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAY--APKHQLLISGGRKGFTYV 2912
T + ++ V +W+++ LVH + H + + H LL +G F +
Sbjct: 674 TCSV---DKKVKIWNSMTG---ELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKL 727
Query: 2913 FDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLST 2959
+DL Q++ R H + V P ++ + SA+G +K+W ++
Sbjct: 728 WDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATS 774
Score = 40.8 bits (94), Expect = 0.021
Identities = 47/218 (21%), Positives = 83/218 (38%), Gaps = 32/218 (14%)
Query: 2754 PTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSL 2813
P L Y G ++G++ + E +++ F+S + T + ++ ++ + +
Sbjct: 971 PHLQYIAFGDENGAIEILELVNNR---IFQSRFQHKKTVWHIQFTADEKTLISSSDDAEI 1027
Query: 2814 YQTNW---KCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDT 2870
NW KC + G H +T DF + +S L++ + T V +W+
Sbjct: 1028 QVWNWQLDKCIFLRG-----------HQETVKDFRLLKNSRLLSWSFDGT----VKVWNI 1072
Query: 2871 LVAPANSLVHAFTCHDSGATVLAYAPKHQLL----ISGGRKGFTYVFDLCQRQQRQLFQS 2926
+ F CH TVL+ H S + + FDL +
Sbjct: 1073 ITGNKEK---DFVCHQG--TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHE--LRG 1125
Query: 2927 HDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLH 2964
H+ V+ A TG G I+IW++S LLH
Sbjct: 1126 HNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLH 1163
Score = 33.1 bits (74), Expect = 4.3
Identities = 21/89 (23%), Positives = 37/89 (41%), Gaps = 1/89 (1%)
Query: 2885 HDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFV 2944
H ++ Q + S G VF ++ ++H+ V A + +
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 2945 TGSAEGNIKIWSLSTFGLLHTFVSEHARQ 2973
T S + +KIW+ T L+HT+ EH+ Q
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTY-DEHSEQ 701
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 117,298,999
Number of Sequences: 37866
Number of extensions: 5320708
Number of successful extensions: 17155
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 16081
Number of HSP's gapped (non-prelim): 1125
length of query: 3027
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2907
effective length of database: 13,703,598
effective search space: 39836359386
effective search space used: 39836359386
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.