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Search of human proteins with 148491080
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
sapiens]
(1723 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 3616 0.0
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 3528 0.0
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s... 1662 0.0
gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] 919 0.0
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ... 767 0.0
gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s... 724 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 109 2e-23
gi|57864582 hornerin [Homo sapiens] 87 1e-16
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 84 2e-15
gi|62122917 filaggrin family member 2 [Homo sapiens] 75 4e-13
gi|60097902 filaggrin [Homo sapiens] 75 7e-13
gi|161016767 mucin 21 [Homo sapiens] 66 3e-10
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 66 3e-10
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 64 1e-09
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 64 2e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 64 2e-09
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 63 3e-09
gi|11761629 fibrinogen, alpha polypeptide isoform alpha prepropr... 63 3e-09
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop... 63 3e-09
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 62 5e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 59 4e-08
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 59 5e-08
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 59 5e-08
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 58 9e-08
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa... 56 3e-07
gi|93141033 PAX interacting protein 1 [Homo sapiens] 55 5e-07
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 55 5e-07
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 55 5e-07
gi|226246533 TOX high mobility group box family member 3 isoform... 55 6e-07
gi|226054295 TOX high mobility group box family member 3 isoform... 55 6e-07
>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
sapiens]
Length = 1723
Score = 3616 bits (9376), Expect = 0.0
Identities = 1723/1723 (100%), Positives = 1723/1723 (100%)
Query: 1 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60
MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP
Sbjct: 1 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60
Query: 61 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120
SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG
Sbjct: 61 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120
Query: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180
GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS
Sbjct: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180
Query: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240
PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG
Sbjct: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240
Query: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300
KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS
Sbjct: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300
Query: 301 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360
NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS
Sbjct: 301 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360
Query: 361 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420
GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG
Sbjct: 361 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420
Query: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480
SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST
Sbjct: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480
Query: 481 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540
GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN
Sbjct: 481 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540
Query: 541 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600
QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC
Sbjct: 541 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600
Query: 601 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660
QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT
Sbjct: 601 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660
Query: 661 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720
KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS
Sbjct: 661 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720
Query: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780
SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI
Sbjct: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780
Query: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840
GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW
Sbjct: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840
Query: 841 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900
GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN
Sbjct: 841 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900
Query: 901 SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWE 960
SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWE
Sbjct: 901 SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWE 960
Query: 961 EEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLS 1020
EEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLS
Sbjct: 961 EEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLS 1020
Query: 1021 QTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGP 1080
QTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGP
Sbjct: 1021 QTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGP 1080
Query: 1081 YFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGL 1140
YFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGL
Sbjct: 1081 YFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGL 1140
Query: 1141 SPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQE 1200
SPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQE
Sbjct: 1141 SPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQE 1200
Query: 1201 QQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPG 1260
QQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPG
Sbjct: 1201 QQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPG 1260
Query: 1261 YGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRG 1320
YGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRG
Sbjct: 1261 YGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRG 1320
Query: 1321 GSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQ 1380
GSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQ
Sbjct: 1321 GSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQ 1380
Query: 1381 NIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDN 1440
NIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDN
Sbjct: 1381 NIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDN 1440
Query: 1441 SFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKP 1500
SFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKP
Sbjct: 1441 SFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKP 1500
Query: 1501 SSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQ 1560
SSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQ
Sbjct: 1501 SSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQ 1560
Query: 1561 HGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQA 1620
HGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQA
Sbjct: 1561 HGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQA 1620
Query: 1621 QPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGA 1680
QPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGA
Sbjct: 1621 QPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGA 1680
Query: 1681 SLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1723
SLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI
Sbjct: 1681 SLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1723
>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
sapiens]
Length = 1833
Score = 3528 bits (9149), Expect = 0.0
Identities = 1710/1833 (93%), Positives = 1712/1833 (93%), Gaps = 110/1833 (6%)
Query: 1 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60
MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP
Sbjct: 1 MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSP 60
Query: 61 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120
SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG
Sbjct: 61 SPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGG 120
Query: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180
GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS
Sbjct: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180
Query: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240
PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG
Sbjct: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240
Query: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300
KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS
Sbjct: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFS 300
Query: 301 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360
NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS
Sbjct: 301 NFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVS 360
Query: 361 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420
GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG
Sbjct: 361 GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG 420
Query: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480
SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST
Sbjct: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRST 480
Query: 481 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540
GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN
Sbjct: 481 GGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDN 540
Query: 541 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600
QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC
Sbjct: 541 QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDC 600
Query: 601 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660
QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT
Sbjct: 601 QAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQT 660
Query: 661 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720
KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS
Sbjct: 661 KNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720
Query: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780
SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI
Sbjct: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780
Query: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840
GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW
Sbjct: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840
Query: 841 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900
GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN
Sbjct: 841 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPN 900
Query: 901 SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSAS------------------------- 935
SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSAS
Sbjct: 901 SYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSP 960
Query: 936 ----------------------------DSKSMQDGWGESDGPVTGARHPSWEEEEDGGV 967
+SKSMQDGWGESDGPVTGARHPSWEEEEDGGV
Sbjct: 961 GWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGV 1020
Query: 968 WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS 1027
WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS
Sbjct: 1021 WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS 1080
Query: 1028 SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK--- 1084
SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK
Sbjct: 1081 SKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTL 1140
Query: 1085 --GGSHGLFG--------------------------------------NSTAQSRGLH-- 1102
G G N A+ G H
Sbjct: 1141 PFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGL 1200
Query: 1103 ------------TPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ 1150
TPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ
Sbjct: 1201 FGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQ 1260
Query: 1151 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1210
LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL
Sbjct: 1261 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320
Query: 1211 QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM 1270
QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM
Sbjct: 1321 QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGM 1380
Query: 1271 DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII 1330
DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII
Sbjct: 1381 DYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDII 1440
Query: 1331 PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV 1390
PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV
Sbjct: 1441 PGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV 1500
Query: 1391 TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA 1450
TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA
Sbjct: 1501 TPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSA 1560
Query: 1451 KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR 1510
KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR
Sbjct: 1561 KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPR 1620
Query: 1511 SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN 1570
SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN
Sbjct: 1621 SVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLN 1680
Query: 1571 LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS 1630
LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS
Sbjct: 1681 LTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPS 1740
Query: 1631 APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS 1690
APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS
Sbjct: 1741 APAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSGADLAGASLWGPPNYSS 1800
Query: 1691 SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1723
SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI
Sbjct: 1801 SLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI 1833
>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
sapiens]
Length = 1029
Score = 1662 bits (4305), Expect = 0.0
Identities = 816/903 (90%), Positives = 827/903 (91%), Gaps = 25/903 (2%)
Query: 828 QPPPPQPEASGSWGGPPPPPPGNVRPSNSSWS-------SGPQPATPKDEEPSGWEEPSP 880
QPPPP G GPPP P+N+ + SG P K P+
Sbjct: 145 QPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAP------ 198
Query: 881 QSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSM 940
D+GTSAWG+PN + + + G N P + +SKSM
Sbjct: 199 ---------DNGTSAWGEPNE---SSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSM 246
Query: 941 QDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGG 1000
QDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGG
Sbjct: 247 QDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGG 306
Query: 1001 NNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRK 1060
NNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRK
Sbjct: 307 NNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRK 366
Query: 1061 DRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP 1120
DRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP
Sbjct: 367 DRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPP 426
Query: 1121 QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 1180
QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ
Sbjct: 427 QFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQ 486
Query: 1181 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 1240
QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM
Sbjct: 487 QQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNM 546
Query: 1241 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 1300
VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA
Sbjct: 547 VPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVA 606
Query: 1301 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 1360
TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK
Sbjct: 607 TQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSK 666
Query: 1361 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 1420
SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN
Sbjct: 667 SSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSN 726
Query: 1421 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 1480
SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI
Sbjct: 727 SSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHI 786
Query: 1481 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 1540
SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL
Sbjct: 787 SSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWL 846
Query: 1541 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 1600
VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN
Sbjct: 847 VLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGN 906
Query: 1601 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 1660
TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST
Sbjct: 907 TTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGST 966
Query: 1661 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1720
GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS
Sbjct: 967 GLGQWSSSAGGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGS 1026
Query: 1721 DSI 1723
DSI
Sbjct: 1027 DSI 1029
Score = 325 bits (833), Expect = 2e-88
Identities = 185/302 (61%), Positives = 206/302 (68%), Gaps = 33/302 (10%)
Query: 2 REKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 61
+EKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS
Sbjct: 38 QEKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPS 97
Query: 62 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 121
PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG
Sbjct: 98 PPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGG 157
Query: 122 AGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSP 181
AGPPPCTAPGANPNNAQVTGALLQSESGTAP + A + S WG S+ G
Sbjct: 158 AGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG--- 214
Query: 182 NPIHIWDKVIVDGSDMEEW---PCIASKDTESSSENTTDN--------NSASNPGSEKST 230
W ++ G+ W P A + +S++ D A +P E+
Sbjct: 215 -----WGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEE 269
Query: 231 LPG--STTSNKGKGSQCQSASSGN------ECNLGVWKSD----PKAKSVQSSN--STTE 276
G +TT ++G S SAS G +C+L +D P AK + S TE
Sbjct: 270 DGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTE 329
Query: 277 NN 278
+N
Sbjct: 330 DN 331
Score = 45.1 bits (105), Expect = 6e-04
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 27/122 (22%)
Query: 633 VWDIEEVPRPE------GKSDKGTEGWESAATQTKNSGGWGDAPS--------QSNQMKS 678
VW P P+ G+ ++ + GW ++ GWG+ P+ S M+
Sbjct: 189 VWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQD 248
Query: 679 GWGELSAST------EWKDPKNTGGWN------DYKNNNSSNWG-GGRPDEKTPSSWNEN 725
GWGE W++ ++ G WN ++NS++WG GG+ K N
Sbjct: 249 GWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNN 308
Query: 726 PS 727
S
Sbjct: 309 DS 310
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 9/111 (8%)
Query: 684 SASTEWKDPKNTG-GWNDYKNNNSSNWGGGRPDEKTPSSWNENP-SKDQGWGGGRQPNQG 741
+ ++ W +P + GW + + +S G G P++ N S GWG P G
Sbjct: 200 NGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTG 259
Query: 742 WSSGKNGWGEEVD----QTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788
+ W EE D T S +S+ S WG+GG+ ++ GGN
Sbjct: 260 --ARHPSWEEEEDGGVWNTTGSQGSASSHNSAS-WGQGGKKQMKCSLKGGN 307
Score = 39.3 bits (90), Expect = 0.033
Identities = 56/250 (22%), Positives = 84/250 (33%), Gaps = 43/250 (17%)
Query: 670 PSQSNQMKSGWGELSASTEWKDPKN---TGGWNDYKNNNSSNWGGGRPD--EKTPSSWNE 724
P + G G + +P N TG ++ + W P + S+W E
Sbjct: 148 PPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGE 207
Query: 725 NPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWG 784
GWG + G S+ GWG N+ +S S GWGE
Sbjct: 208 PNESSPGWG--EMDDTGAST--TGWGNTPANAPNAMKPNSKSMQ-DGWGE---------- 252
Query: 785 NGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPP 844
+ G + A WE+ + WN TG Q ++ + AS GG
Sbjct: 253 SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN---------------SASWGQGGKK 297
Query: 845 PPPPGNVRPSNSSWS-------SGPQPATPKDEEPSGWEEPSPQSIS-RKMDIDDGTSAW 896
+N SW S + ++ PS + S S+S +K D+D
Sbjct: 298 QMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNL 357
Query: 897 GDPNSYNYKN 906
GD N K+
Sbjct: 358 GDFNDIMRKD 367
Score = 32.0 bits (71), Expect = 5.3
Identities = 39/160 (24%), Positives = 60/160 (37%), Gaps = 7/160 (4%)
Query: 295 PGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG 354
P G N +P S+P P V GT+ ++TD + + +T G S S
Sbjct: 681 PWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTD--HQLLRDNTTGSNSSLNTSLPSPGA 738
Query: 355 VNFVVSGREQAQIHNTDG--PKNGNTNSLNLSSPNP--MENKGMPFGMGLGNTSRSTDAP 410
+ S +H+T P +T S + NP + NK + NT+ P
Sbjct: 739 WPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPP 798
Query: 411 SQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNG 450
T + K S S A R G T + S + ++G
Sbjct: 799 PGLT-NPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDG 837
>gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
Length = 1962
Score = 919 bits (2375), Expect = 0.0
Identities = 708/2018 (35%), Positives = 963/2018 (47%), Gaps = 378/2018 (18%)
Query: 7 EREEQLMEDKKRKKEDKKKKEATQK-VTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVN 65
+ EEQLME+KK+KK+DKKKKEA QK TEQK KVPE KPS+SQP A+ + S +
Sbjct: 22 QEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANS-NNGTSTATS 80
Query: 66 GGNNAKRVAVPNGQP------------------------------PSAARYMPREVPPRF 95
NNAKR N QP P A PREVPPRF
Sbjct: 81 TNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRF 140
Query: 96 RCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQV--TGALLQSESGTAPD 153
R Q+HK LLKRGQ P LG + + N Q G + S++ + +
Sbjct: 141 R-HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDIN 199
Query: 154 STLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSE 213
+ G S+Y NS G +S TS + + + V+ D S+ E WP D E +SE
Sbjct: 200 HSTSG---SHYENSQRGPVSS----TSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASE 252
Query: 214 NTTDNNSASNPGSEKSTL---PGSTTSNK-------GKGSQ------CQSASSGNECNLG 257
D +SAS+ SE++ G+T K G GSQ S + G+ + G
Sbjct: 253 -CMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTG 311
Query: 258 VWKSDPKA------KSVQSSNSTTEN-NNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSA 310
W A SV + S +E+ NN + W VS G S N SN A
Sbjct: 312 PWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNP--STLNSASNHGA 369
Query: 311 WPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG---------------- 354
WP L G + KG + + +S + Q ST+GQ Q + +G
Sbjct: 370 WPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCES 429
Query: 355 -------VNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPN---------PMENKG----- 393
V+F SG+ Q GP N TN + S PN P N G
Sbjct: 430 EVSGTQKVSF--SGQPQNITTEMTGPNN-TTNFMTSSLPNSGSVQNNELPSSNTGAWRVS 486
Query: 394 ------MPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNG 447
M G+ TS S S G+ K+G GS+G G G S S +G
Sbjct: 487 TMNHPQMQAPSGMNGTSLS----HLSNGESKSG--GSYGTTWGAYG----SNYSGDKCSG 536
Query: 448 NNGKEREDSWKGASVQKST-GSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506
NG+ D+ +Q G ++ N GG W G +S WG GN SG
Sbjct: 537 PNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGG 596
Query: 507 SQGEWKQP---TGSDELKIGEWSG-PNQPNSSTGAWDNQKGHPL------PENQGNA--- 553
S+ W P TG++ L EW+ P+ +S+ A N K E+QG+A
Sbjct: 597 SRRGWGTPAQNTGTN-LPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQ 655
Query: 554 ---QAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSR 610
Q+ W ++ + S+ +STG + G+ +S + RR D +LQ++++R
Sbjct: 656 TNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKI-----DQHTLLQSIVNR 710
Query: 611 TDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAP 670
TDLDPRVLSN+GWGQT IKQ+T WD E PR E K+D GTE W S+ATQT NSG D
Sbjct: 711 TDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKT 770
Query: 671 SQSNQ---MKSGWGELSASTEWKDPKNT---GGWNDYKNNN----SSNWGGGRPDEKTPS 720
S + SGWG+ + W D K + GGW D S+ WG + ++ +
Sbjct: 771 SPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEK---A 827
Query: 721 SWNENPSKDQGWGGGRQPNQGWS----------SGKNGWGEEVDQTKNSNWESSASKPVS 770
+WN++ QGWG G++ +QGWS S N WGE K+S+ S + + VS
Sbjct: 828 AWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEA--NKKSSSGGSDSDRSVS 885
Query: 771 GWGEGGQNEIGTWGNGGNASLAS----------KGGWED---CKRSPAWNETGRQPNS-- 815
GW E G+ TWGN N + +S GW D +S W ++ + +S
Sbjct: 886 GWNELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPD 945
Query: 816 WNKQHQQQQPPQQPPPP-QPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPK-----D 869
WNKQ PP +P +G GGP P P P+ W P P + + D
Sbjct: 946 WNKQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEEEPTG--WEE-PSPESIRRKMEID 1002
Query: 870 EEPSGWEEPS--------------------------------PQSISRKMDIDDGTS--- 894
+ S W +PS P S + G+
Sbjct: 1003 DGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGE 1062
Query: 895 AWGDPNSYNY---KNVNLWDKNSQGGPAPREPNLPTPMTSKSASDS-----------KSM 940
WG+P++ + W K GP+ EP TS S S KSM
Sbjct: 1063 PWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKSM 1122
Query: 941 QDGWGESDGPVTGARHPSWEEEEDG--GVWNTTGSQGSASSHN-------SASWGQGGKK 991
QDGW D P+ G R WEEEED G+WN+ SQ SS N +S G GKK
Sbjct: 1123 QDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKK 1182
Query: 992 QMK--CSLKGGNN--DSWMNPLAKQFSNMGLL--SQTEDNPSSKMDLSVGSLSDKKFDVD 1045
+ + +KGGN ++W+NP KQFSN+ S E+ S+KMDLS G L DK+ ++D
Sbjct: 1183 RRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEID 1242
Query: 1046 KRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK--------------------- 1084
K ++N+GD+N + K G RP SK+ + + PYF+K
Sbjct: 1243 KHSLNIGDYNRTVGKG-PGSRPQISKE-SSMERNPYFDKDGIVADESQNMQFMSSQSMKL 1300
Query: 1085 ----------------------------GGSHGLFG--NSTAQSRGLHTP-VQPLNSS-P 1112
G+ +FG N+ AQ RG+ P QPL+SS P
Sbjct: 1301 PPSNSALPNQALGSIAGLGMQNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQP 1360
Query: 1113 SLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLAC 1172
+LRAQVPP +SPQV S+LK PN+G + P PQQ+AML+QL Q+ Q
Sbjct: 1361 NLRAQVPPPLLSPQVPVSLLKYAPNNG------GLNPLFGPQQVAMLNQLSQLNQLSQIS 1414
Query: 1173 QL--LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQ----------QQRQ 1220
QL LL QQQ+ Q +QR + R QQ+QQ R +S QQ QQ +Q+
Sbjct: 1415 QLQRLLAQQQRAQ---SQRSVPSGNRPQQDQQ-GRPLSVQQQMMQQSRQLDPNLLVKQQT 1470
Query: 1221 PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIP-----GYGSGFSSGGMDYGMV 1275
P + P H K LDN++P+ P+LQ KGP P + G +S ++ M
Sbjct: 1471 PPSQQQPLHQPAMKSFLDNVMPHTT----PELQ-KGPSPINAFSNFPIGLNSN-LNVNMD 1524
Query: 1276 GGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTL 1335
+SR ++WT++ + + + + N K+GAI + G SP+ +D + T
Sbjct: 1525 MNSIKEPQSRLRKWTTV-DSISVNTSLDQNSSKHGAI-SSGFRLEESPFVPYDFMNSSTS 1582
Query: 1336 -GGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGS 1394
G GD W AKSP + SS+ +WPPEF+PG PWKG NIDPE+DPYVTPGS
Sbjct: 1583 PASPPGSIGDGWPRAKSP------NGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGS 1636
Query: 1395 VLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNS----FTNVHSTSA 1450
V+ + + + + DH LRD +GS+SSLNT+LPS AW + N + STSA
Sbjct: 1637 VINNLSINTVREVDH--LRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSA 1694
Query: 1451 KFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPS-SPWSSTAP 1509
+ D K TWSP + + T L++++WK + +N T RPPPGLT KP S W ++
Sbjct: 1695 RNSDSKLTWSPGSVTN--TSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPL 1752
Query: 1510 RSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHL 1569
R GWG D+R S+W + S R + WLVL NLTPQIDGSTLRT+CMQHGPL+TFHL
Sbjct: 1753 RIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHL 1812
Query: 1570 NLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATP 1629
NL G AL+RYS+K+E KAQ +LHMCVLGNTTILAEFA+++E+SRF AQ+Q T
Sbjct: 1813 NLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLT----- 1867
Query: 1630 SAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSA-GGSSGADLAGASLWGPPNY 1688
P+ GWQSL + Q++ + + F T L W+ + G++ DL G SLWG P+Y
Sbjct: 1868 --PSPGWQSLGSSQSRLGSL-DCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWGTPHY 1924
Query: 1689 SSSLWGVPTVEDPHRMGSPAPL---LPGDLLGGGSDSI 1723
S+SLWG P+ DP + SP+P+ L D LGGG +S+
Sbjct: 1925 STSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM 1962
>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
sapiens]
Length = 1726
Score = 767 bits (1981), Expect = 0.0
Identities = 628/1804 (34%), Positives = 820/1804 (45%), Gaps = 383/1804 (21%)
Query: 208 TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267
T+ ++ N N + S +S L ++ G ++ ++G+ L S
Sbjct: 14 TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66
Query: 268 VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
V + + G G +N G G N NPN+NP+AWP L EGT G
Sbjct: 67 VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121
Query: 328 DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370
+ S+ + VS +GQ Q +S + VS Q Q NT
Sbjct: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181
Query: 371 DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415
DGP N TN +N SSPNP+ N GM GMG G + + SQ +G
Sbjct: 182 DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238
Query: 416 DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474
G S WG + G T G SNSG + NG D+ A K GS S
Sbjct: 239 GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288
Query: 475 NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530
S G +W+ GP WG G N + G W P+ S + GEW P
Sbjct: 289 QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346
Query: 531 PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578
PN + + N KG P +Q P W +++SS + G S GS NH
Sbjct: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406
Query: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638
GS+ +G R Q +Q L R DLDPRVLSNTGWGQT +KQ+T W+ EE
Sbjct: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464
Query: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690
PR E K+D GTE W AATQ NSGG D S + SGW + A+T W
Sbjct: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524
Query: 691 D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734
D P G W D ++ + + W G E +W E P K Q WG
Sbjct: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584
Query: 735 GRQPNQGWSSGKNGWGEEV-------DQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786
G++ N WS+G W + D KN S W++ +++ SGW + ++ WGN
Sbjct: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644
Query: 787 GNASLASKGGW-EDCKRSPA--WNETGRQPNSWN-----------------------KQH 820
N W E K P W + N N K
Sbjct: 645 TNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDS 704
Query: 821 QQQQPPQQPPPPQ-------PEASGSWGGP------------------------------ 843
+ ++P PP + + +WG P
Sbjct: 705 SEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTT 764
Query: 844 -------------PPPPPGNVR--------PSNSSWSSGPQPATPKDEEPSGWEEPSPQS 882
PPP + P +S W P + + + W EPS S
Sbjct: 765 TTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTE---NSWGEPSSPS 821
Query: 883 ISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNL-------PTPMTSKSAS 935
+D+GT+AWG P S S G P EP + P ++
Sbjct: 822 TL----VDNGTAAWGKPPS----------SGSGWGDHPAEPPVAFGRAGAPVAASALCKP 867
Query: 936 DSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKC 995
SKSMQ+GWG S G WE+EE G VWN SQ S SS +SWG KK ++
Sbjct: 868 ASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAASQESTSS--CSSWGNAPKKGLQK 923
Query: 996 SLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP----SSKMDLSVGSLSDKKFDVDKRA 1048
+K G +++W M+ L KQ ++MG + + + +D ++ +L +KK DVDKR
Sbjct: 924 GMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRG 983
Query: 1049 MNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGG---------------------S 1087
+ + D N + K G RPP SK+ + D + +K G S
Sbjct: 984 LGVTDHNGMAAKP-LGCRPPISKE-SSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLS 1041
Query: 1088 H-------------------------------GLFGNS-TAQSRGL----HTPVQPLNSS 1111
H G+FGNS AQ+R + PVQPLNSS
Sbjct: 1042 HSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSS 1101
Query: 1112 -PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQ 1169
PSLRAQV PQF+SPQV A +L+ N GL+P L ++PQ + ML+QL Q+ Q
Sbjct: 1102 QPSLRAQV-PQFLSPQVQAQLLQFAAKNIGLNPALLT--SPINPQHMTMLNQLYQL---Q 1155
Query: 1170 LACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQ--------- 1220
LA Q L Q QQQ+LQ QR +S ++R QQEQQ+AR ++ LQQQ QQ QRQ
Sbjct: 1156 LAYQRL---QIQQQMLQAQRNVSGSMR-QQEQQVARTITNLQQQIQQHQRQLAQALLVKQ 1211
Query: 1221 ----PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG-----------PIPGYGSGF 1265
P H HP K +D+ + GLPDLQTK P+ G
Sbjct: 1212 PPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNM 1271
Query: 1266 SSGGMDYGMVGG----KEAGTESRFKQWT--SMMEGLPSVATQ-EANMHKNGAIVA---- 1314
+ MD M GG + ++SR QWT + M+ LPS A+ E N K+GAI
Sbjct: 1272 NVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSI 1329
Query: 1315 --PGKTRGGSPYNQFDIIP-GDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQ 1371
PGK+ Y ++D+I ++ SW AKS ++KI S S+ +WPPEF
Sbjct: 1330 GPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKS-DSDKI-SNGSSINWPPEFH 1387
Query: 1372 PGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSP 1430
PGVPWKG+QNIDPE+DP VTPGSV G T + I D + LL+ + SS N +LPS
Sbjct: 1388 PGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSS 1447
Query: 1431 GAWP-----YSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNT 1485
AWP YS+S +S + S + K D KSTWS P H LS+++WK RN+
Sbjct: 1448 SAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHELWK---VPRNS 1504
Query: 1486 TPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNL 1545
T RPPPGLTNPKPSS W + S GW S +S S WS S R S WLVL NL
Sbjct: 1505 TAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWSTDTSGRTSSWLVLRNL 1557
Query: 1546 TPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILA 1605
TPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKAQ +LHMCVLGNTTILA
Sbjct: 1558 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA 1617
Query: 1606 EFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGL--- 1662
EFA ++EV+RFLAQ Q A P P + WQS P L+ G S GL
Sbjct: 1618 EFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ------PRLSAAGSSHGLVRS 1664
Query: 1663 --GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHRMGSPAP---LLPGDLL 1716
G W++ G G + LW G P YSSSLWG P+ +D +GSP P LLPGDLL
Sbjct: 1665 DAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLL 1721
Query: 1717 GGGS 1720
G S
Sbjct: 1722 SGES 1725
Score = 43.9 bits (102), Expect = 0.001
Identities = 96/497 (19%), Positives = 178/497 (35%), Gaps = 86/497 (17%)
Query: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186
C A A+ + + G+++ S + ++ + A+ AN+ WG +N +P+ +
Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536
Query: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
W I W A+++ +S + + + G + + P +
Sbjct: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594
Query: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293
G G S+S + N W +D +++T N+G GN N
Sbjct: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649
Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344
NP +N W ++ G + A + ++N S ++V QT
Sbjct: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697
Query: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396
+Q+ E G + ++ DG P N N ++N+ N N +
Sbjct: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754
Query: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454
T+ +T S +T +T G R P SG G N + E
Sbjct: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGW---GEMPNVHSKTE 811
Query: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514
+SW G ST N G+ +G S+ + WG+ + V+ G P
Sbjct: 812 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 858
Query: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563
S ++ G SG ++ N ST W++++G + + + WG ++
Sbjct: 859 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 917
Query: 564 STGSEVGGQSTGSNHKA 580
G + G +++G +A
Sbjct: 918 KKGLQKGMKTSGKQDEA 934
>gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo
sapiens]
Length = 1690
Score = 724 bits (1870), Expect = 0.0
Identities = 619/1805 (34%), Positives = 804/1805 (44%), Gaps = 421/1805 (23%)
Query: 208 TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267
T+ ++ N N + S +S L ++ G ++ ++G+ L S
Sbjct: 14 TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66
Query: 268 VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
V + + G G +N G G N NPN+NP+AWP L EGT G
Sbjct: 67 VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121
Query: 328 DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370
+ S+ + VS +GQ Q +S + VS Q Q NT
Sbjct: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181
Query: 371 DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415
DGP N TN +N SSPNP+ N GM GMG G + + SQ +G
Sbjct: 182 DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238
Query: 416 DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474
G S WG + G T G SNSG + NG D+ A K GS S
Sbjct: 239 GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288
Query: 475 NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530
S G +W+ GP WG G N + G W P+ S + GEW P
Sbjct: 289 QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346
Query: 531 PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578
PN + + N KG P +Q P W +++SS + G S GS NH
Sbjct: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406
Query: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638
GS+ +G R Q +Q L R DLDPRVLSNTGWGQT +KQ+T W+ EE
Sbjct: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464
Query: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690
PR E K+D GTE W AATQ NSGG D S + SGW + A+T W
Sbjct: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524
Query: 691 D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734
D P G W D ++ + + W G E +W E P K Q WG
Sbjct: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584
Query: 735 GRQPNQGWSSG------------------KNGWGEEVDQTK------------NSNWESS 764
G++ N WS+G KNG G + D + NS W +S
Sbjct: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644
Query: 765 AS---KPVSGWGE----GGQ---------NEIGTWGNGGNASLASKG------------- 795
+ P + WGE G Q N + WG + G
Sbjct: 645 TNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDS 704
Query: 796 ----GWEDCKR------------SPAW----NETGRQPNSWNKQHQQQQPPQ-------- 827
GWE+ + AW N + N W++ + Q
Sbjct: 705 SEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTT 764
Query: 828 -----------QPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWE 876
+ PPP +A P PG R +S W P + + + W
Sbjct: 765 TTTTSNTTHRVETPPPH-QAGTQLNRSPLLGPG--RKVSSGWGEMPNVHSKTE---NSWG 818
Query: 877 EPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNL-------PTPM 929
EPS S +D+GT+AWG P S S G P EP + P
Sbjct: 819 EPSSPSTL----VDNGTAAWGKPPS----------SGSGWGDHPAEPPVAFGRAGAPVAA 864
Query: 930 TSKSASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGG 989
++ SKSMQ+GWG S G WE+EE G VWN SQ S SS +SWG
Sbjct: 865 SALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAASQESTSS--CSSWGNAP 920
Query: 990 KKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP----SSKMDLSVGSLSDKKF 1042
KK ++ +K G +++W M+ L KQ ++MG + + + +D ++ +L +KK
Sbjct: 921 KKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKV 980
Query: 1043 DVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGG---------------- 1086
DVDKR + + D N + K G RPP SK+ + D + +K G
Sbjct: 981 DVDKRGLGVTDHNGMAAKP-LGCRPPISKE-SSVDRPTFLDKDGGLVEEPTPSPFLPSPS 1038
Query: 1087 -----SH-------------------------------GLFGNS-TAQSRGL----HTPV 1105
SH G+FGNS AQ+R + PV
Sbjct: 1039 LKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPV 1098
Query: 1106 QPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQLSPQQIAMLSQLP 1163
QPLNSS PSLRAQV PQF+SPQV A +L+ N GL+P L ++PQ + ML+QL
Sbjct: 1099 QPLNSSQPSLRAQV-PQFLSPQVQAQLLQFAAKNIGLNPALLT--SPINPQHMTMLNQLY 1155
Query: 1164 QIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQ--- 1220
Q+ QLA Q L Q QQQ+LQ QR +S ++R QQEQQ+AR ++ LQQQ QQ QRQ
Sbjct: 1156 QL---QLAYQRL---QIQQQMLQAQRNVSGSMR-QQEQQVARTITNLQQQIQQHQRQLAQ 1208
Query: 1221 ----------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG-----------PIP 1259
P H HP K +D+ + GLPDLQTK P+
Sbjct: 1209 ALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLA 1268
Query: 1260 GYGSGFSSGGMDYGMVGG----KEAGTESRFKQWT--SMMEGLPSVATQ-EANMHKNGAI 1312
G + MD M GG + ++SR QWT + M+ LPS A+ E N K+GAI
Sbjct: 1269 GLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAI 1326
Query: 1313 VA------PGKTRGGSPYNQFDIIP-GDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNAS 1365
PGK+ Y ++D+I ++ SW AKS ++KI S S+ +
Sbjct: 1327 PGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKS-DSDKI-SNGSSIN 1384
Query: 1366 WPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQLLRDNTTGSNSSLN 1424
WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T + I D + LL+
Sbjct: 1385 WPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLK----------- 1433
Query: 1425 TSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRN 1484
+ K D KSTWS P H LS+++WK RN
Sbjct: 1434 -----------------------SGGKLSDIKSTWSSGPTSHTQASLSHELWK---VPRN 1467
Query: 1485 TTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHN 1544
+T RPPPGLTNPKPSS W + S GW S +S S WS S R S WLVL N
Sbjct: 1468 STAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWSTDTSGRTSSWLVLRN 1520
Query: 1545 LTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTIL 1604
LTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKAQ +LHMCVLGNTTIL
Sbjct: 1521 LTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTIL 1580
Query: 1605 AEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGL-- 1662
AEFA ++EV+RFLAQ Q A P P + WQS P L+ G S GL
Sbjct: 1581 AEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ------PRLSAAGSSHGLVR 1627
Query: 1663 ---GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHRMGSPAP---LLPGDL 1715
G W++ G G + LW G P YSSSLWG P+ +D +GSP P LLPGDL
Sbjct: 1628 SDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDL 1684
Query: 1716 LGGGS 1720
L G S
Sbjct: 1685 LSGES 1689
Score = 44.3 bits (103), Expect = 0.001
Identities = 95/497 (19%), Positives = 177/497 (35%), Gaps = 83/497 (16%)
Query: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186
C A A+ + + G+++ S + ++ + A+ AN+ WG +N +P+ +
Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536
Query: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
W I W A+++ +S + + + G + + P +
Sbjct: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594
Query: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293
G G S+S + N W +D +++T N+G GN N
Sbjct: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649
Query: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344
NP +N W ++ G + A + ++N S ++V QT
Sbjct: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697
Query: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396
+Q+ E G + ++ DG P N N ++N+ N N +
Sbjct: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754
Query: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454
T+ +T S +T +T G R P S G N + E
Sbjct: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTE 814
Query: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514
+SW G ST N G+ +G S+ + WG+ + V+ G P
Sbjct: 815 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 861
Query: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563
S ++ G SG ++ N ST W++++G + + + WG ++
Sbjct: 862 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 920
Query: 564 STGSEVGGQSTGSNHKA 580
G + G +++G +A
Sbjct: 921 KKGLQKGMKTSGKQDEA 937
Score = 32.7 bits (73), Expect = 3.1
Identities = 64/273 (23%), Positives = 90/273 (32%), Gaps = 43/273 (15%)
Query: 1466 HNPTHLSNKMWKNHISSRNTTPLPRPPPGLT-NPKPSSPWSSTAP-RSVRGWGTQDSRLA 1523
++ T N W N S NT P G T P P W+S +V WG S
Sbjct: 631 NDTTRSGNSGWGN---STNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQ 687
Query: 1524 SASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTAL----IR 1579
+ + W GG V Q D S P + + + GT+
Sbjct: 688 TGTGWI-GGPVP----------VKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSN 736
Query: 1580 YSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSL 1639
Y+ K ++M N I + T+ + + TP AG Q
Sbjct: 737 YNNK--------TVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQL- 787
Query: 1640 ETGQNQSDPVGPALNLFGG--------STGLGQWSSSAGGSSGADLAGASLWGPPNYSSS 1691
N+S +GP + G S W + S+ D G + WG P S S
Sbjct: 788 ----NRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVD-NGTAAWGKPPSSGS 842
Query: 1692 LWGVPTVEDPHRMG-SPAPLLPGDLLGGGSDSI 1723
WG E P G + AP+ L S S+
Sbjct: 843 GWGDHPAEPPVAFGRAGAPVAASALCKPASKSM 875
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 109 bits (273), Expect = 2e-23
Identities = 154/839 (18%), Positives = 305/839 (36%), Gaps = 45/839 (5%)
Query: 146 SESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIAS 205
S+S A D + +N ++S G+G NNG N K D SD + S
Sbjct: 505 SDSKGAEDDDSDSTSDTNNSDSN-GNG---NNGNDDNDKSDSGKGKSDSSDSDSSDSSNS 560
Query: 206 KDTESSSEN-TTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
D+ SS++ ++D+NS+S+ S S S+ S+ S +S ++ + SD
Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD-- 618
Query: 265 AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGA 324
+ +S +S +E+++ + ++ S S S+ + +SN S S +
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 325 LETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLS 384
+D+SNSS + ++ + S + + ++D + N+NS +
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESS-----------DSSDSSDSDSSDSSDSSNSNSSDSD 727
Query: 385 SPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSG 444
S N ++ ++S S+++ S + S S ++ +D S S+
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD--SSNSSDS 785
Query: 445 NNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTS 504
N+ +N + DS + S+ S + S +++ S+ S + DS+D+ + +S
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 505 GVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSS 564
S GSD N +SS + + + N + S SS
Sbjct: 846 DSSD-------GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898
Query: 565 TGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWG 624
S+ S+ S++ + SSDS NS S D + S D SN+
Sbjct: 899 NSSD--SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 625 QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684
D + SD S ++ + +S D+ SN S + S
Sbjct: 957 SNSSDSSNSSDSSD----SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS--SDSS 1010
Query: 685 ASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSS 744
S++ + ++ +D N++ S+ D S +++ + SS
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 745 GKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSP 804
+ + D +++S+ S++ S + + + ++ + D S
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 805 AWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQP 864
+++ NS + + ++S S + SNSS SS
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD--SSNSSDSSDSSD 1188
Query: 865 ATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPN 924
++ + + S D D + + +S + + N +S + N
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248
Query: 925 LPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSA 983
S +SDS S + +S + + + D S+GS S+H+++
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD--------SEGSDSNHSTS 1299
Score = 103 bits (258), Expect = 1e-21
Identities = 144/821 (17%), Positives = 293/821 (35%), Gaps = 62/821 (7%)
Query: 133 NPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192
N NN S G + S + +SN ++S+ S + S++ S + D
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588
Query: 193 DGSDMEEWPCIASKDTESSSE--NTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASS 250
D SD + S D+ SS+ +++D++ +S+ S+ S ++ + K S SS
Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Query: 251 GNECNLGVWKSDPKAKSVQSSNST-TENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPS 309
+ N S + S SS+S+ + +++ + N S S S + +S+ S
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 310 AWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHN 369
+ +S + ++D+SNSS + + S N+ + S + +
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 370 TDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAAR 429
+ +++S N S N N+S S+D+ + S + S S ++
Sbjct: 769 DSSDSSDSSDSSNSSDSNDS-----------SNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Query: 430 GPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQ 489
S + S S+ ++ +N + DS + S S N++ S+ S +
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 490 DSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPEN 549
DS+D+ + N+ ++ + + SD + S + + S+ + D+ + +N
Sbjct: 878 DSSDS--SDSNESSNSSDSSDSSNSSDSDS---SDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 550 QGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLS 609
++ SS+S+ S S+ S+ + SSDS NS S
Sbjct: 933 SNSSD------SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS----------------D 970
Query: 610 RTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDA 669
D SN+ D + SD S ++ + NS ++
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 670 PSQSNQM-KSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSK 728
S+ S + S S++ D N+ +D +++ S+ D S +++
Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090
Query: 729 DQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788
+ SS + + D + +SN S+ S N + + +
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150
Query: 789 ASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPP 848
+ + D S +++ +S N ++S S
Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS--------- 1201
Query: 849 GNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVN 908
S+SS SS ++ + + + D D + + NS + +
Sbjct: 1202 -----SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD-- 1254
Query: 909 LWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDG 949
+S + + N + SKS + + + D +S+G
Sbjct: 1255 ----SSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG 1291
Score = 101 bits (252), Expect = 5e-21
Identities = 148/863 (17%), Positives = 291/863 (33%), Gaps = 53/863 (6%)
Query: 144 LQSESGTAPDSTLGGAAASNYA--NSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWP 201
+Q + + D + G A++ + NS+ AS N+ S + + D + D +
Sbjct: 460 MQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTS 519
Query: 202 CIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKS 261
+ D+ + N D+N S+ G KS S +S+ S S SS ++ + S
Sbjct: 520 DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD-SSDSSDSDSSDSNSSS 578
Query: 262 DPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSR 321
D + SS+S+ +++ N + S S S+ + + + S+ +
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638
Query: 322 KGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSL 381
K NS+ S+ S +S S + + S +++D + ++++
Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698
Query: 382 NLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQS 441
+ SS + + + S S+D+ S ++ D S S + S + S S
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 442 NSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNK 501
+ +N ++ + DS S + + +DS D++N S + SN + + +
Sbjct: 759 SDSSNSSDSSDSSDS----SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814
Query: 502 MTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRS 561
+ S SD S + + S+ D+ + + + + S
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD----S 870
Query: 562 SSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNT 621
S S+ S S+ SN + SSDS +S S D D SN+
Sbjct: 871 SDSSNSSDSSDSSDSNESSNSSDSSDSSNSS-------------------DSDSSDSSNS 911
Query: 622 GWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWG 681
D + S+ S ++ + NS D+ SN S
Sbjct: 912 S------------DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 682 ELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQG 741
S+++ N+ +D N++ S+ D S + + N
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 742 WSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCK 801
SS + D + +S+ S+ S N + + ++ + D
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 802 RSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSG 861
S +++ NS + ++S S SNSS SS
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS-----------SNSSDSSD 1128
Query: 862 PQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPR 921
++ + + + S D D + + +S + + + +S +
Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188
Query: 922 EPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN 981
+ S +SDS D SD + S + + +++ S S+ S N
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248
Query: 982 SASWGQGGKKQMKCSLKGGNNDS 1004
S+ S +DS
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDS 1271
Score = 100 bits (250), Expect = 9e-21
Identities = 133/680 (19%), Positives = 262/680 (38%), Gaps = 57/680 (8%)
Query: 133 NPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIV 192
N +++ + + S+S + DS+ +++S+ +NS+ S +S ++ +S +
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSS-DSSSSSDSSNSSDSSDSSDSSNSSESS--------- 702
Query: 193 DGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGN 252
D SD + +S ++SS+ N++D++S+++ S S+ ++ + + S+ S +
Sbjct: 703 DSSDSSDSD--SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760
Query: 253 ECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWP 312
N SD S S +S + N++ + N S S SN + +S+ S
Sbjct: 761 SSN----SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS--- 813
Query: 313 ALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDG 372
+ + + +D+SNSS S +S S + G + S R + +++D
Sbjct: 814 ----DSSDSDSSNSSDSSNSS-DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS-NSSDS 867
Query: 373 PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPS 432
+ ++++ + SS + N+ N+S S+D+ + S D S S + S
Sbjct: 868 SDSSDSSNSSDSSDSSDSNES-------SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920
Query: 433 GTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKN--------DSWDNNNRSTGGSW 484
+ S S+ +N ++ DS + S+ S N DS D+N+ + S
Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980
Query: 485 NFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH 544
N + + + S S SD + S + ++S+ + D+
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 545 PLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604
++ ++ + SS S+ S S+ S+ + SSDS S S D
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100
Query: 605 QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664
+ S D S++ D + SD S ++ + +S
Sbjct: 1101 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160
Query: 665 GWGDAPSQSNQM-------------KSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGG 711
D+ S+ S + S S++ D ++ +D +++ S+
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Query: 712 GRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWES-SASKPVS 770
D S NE+ N SS + + D T +SN ES S SK +
Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSN---SSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277
Query: 771 GWGEGGQNEIGTWGNGGNAS 790
G G ++ + G+ N S
Sbjct: 1278 GNNNGSDSDSDSEGSDSNHS 1297
Score = 98.2 bits (243), Expect = 6e-20
Identities = 112/616 (18%), Positives = 233/616 (37%), Gaps = 28/616 (4%)
Query: 146 SESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIAS 205
S+S + +S + +SN ++S+ S +S ++ +S + D S+ + +
Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772
Query: 206 KDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLG-VWKSDPK 264
S S N++D+N +SN + S +SN S +S + N S
Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832
Query: 265 AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGA 324
+ S SS+S+ +++ G+ + S + S S+ + +SN S S +
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 325 LETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLS 384
+D+SNSS S+ S + ++ + ++ N+ N + +S +
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSS---------DSSESSNSSDNSNSSDSSNSSD 943
Query: 385 SPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSG 444
S + ++ ++S S+D+ ++ D S S + S + S S++
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Query: 445 NNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTS 504
++ ++ + DS + S+ S N S +++ + S + + + + S
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Query: 505 GVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSS 564
S SD E S + ++S+ + D+ ++ ++ + SS+S
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 565 TGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWG 624
+ S S+ S+ + SSDS +S S D + S D SN+
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-- 1181
Query: 625 QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684
D + SD S ++ + +S D+ S+ S + S
Sbjct: 1182 ----------DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS--SDSS 1229
Query: 685 ASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSS 744
S E D ++ +D N++ S+ + + S+ + N D G N G S
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSS----DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285
Query: 745 GKNGWGEEVDQTKNSN 760
+ G + + + + +
Sbjct: 1286 DSDSEGSDSNHSTSDD 1301
Score = 91.7 bits (226), Expect = 6e-18
Identities = 166/893 (18%), Positives = 304/893 (34%), Gaps = 47/893 (5%)
Query: 207 DTESSSENTTDNNSASNPGSEK---STLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP 263
D +SS +D+ +P ++ + + G TS + S +G++ K +
Sbjct: 290 DHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNH 349
Query: 264 KAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKG 323
+ + T E+ G + GP SG N EG KG
Sbjct: 350 RESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKG------NEGKEDKG 403
Query: 324 --ALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSL 381
+ N Q V Q+S+ N V N+DG + + +
Sbjct: 404 QHGMILGKGNVKTQGEVVNIEGPGQKSEPGNK-----VGHSNTGSDSNSDGYDSYDFDDK 458
Query: 382 NLSSPNPME----NKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTV 437
++ +P N N S S S ++ + K GS +D+
Sbjct: 459 SMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDST 518
Query: 438 SGQSNS-----GNNGNNGKEREDSWKGASVQKSTGS-----KNDSWDNNNRSTGGSWNFG 487
S +NS GNNGN+ ++ DS KG S + S +DS D+++ + S +
Sbjct: 519 SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578
Query: 488 PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547
DS+D+ + + S S SD + S + S + ++
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD--S 636
Query: 548 ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTL 607
+++ ++ SS ++ S S+ S+ + SSDS +S S D +
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 608 LSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWG 667
S D S++ + ++ + SD S ++ + NS
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 668 DAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPS 727
D+ SN S + S S++ D N+ ND N++ S+ + + SS + N S
Sbjct: 757 DSSDSSNSSDS--SDSSDSSDSSDSSNSSDSNDSSNSSDSS-------DSSNSSDSSNSS 807
Query: 728 KDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGG 787
+ SS + + D + NS+ S +S G N + +
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSD-SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 788 NASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP 847
++ + D S NE+ +S + + + S
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 848 PGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNV 907
+ SNSS SS ++ + + + + S D D S+ +S N +
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS-DSSDSSNSSDS 985
Query: 908 NLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGV 967
+ +S + N S +SDS + D SD + S + +
Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045
Query: 968 WNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPS 1027
+++ S S++S +S+ S ++DS + + SN S + D+ S
Sbjct: 1046 SDSSDSSDSSNSSDSSD-SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS-S 1103
Query: 1028 SKMDLSVGSLSDKKFDVDKR--AMNLGDFNDIMRKDRSGFRPPNSKDMGTTDS 1078
D S S S D + + D +D S +S+ ++DS
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDS 1156
Score = 85.1 bits (209), Expect = 5e-16
Identities = 175/919 (19%), Positives = 303/919 (32%), Gaps = 135/919 (14%)
Query: 184 IHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGS 243
+ + D++ G+ E + D ENT D + GS+ + + G + S
Sbjct: 42 VSVQDELNASGTIKESGVLVHEGD-RGRQENTQDGHKGEGNGSKWAEVGGKSFST----- 95
Query: 244 QCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGL-GNWRNVSGQDRIGPGSGFSNF 302
S + E N+ W D + + T ++G+ G N++ G S N
Sbjct: 96 --YSTLANEEGNIEGWNGD-------TGKAETYGHDGIHGKEENITANGIQGQVSIIDN- 145
Query: 303 NPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGR 362
GA N+N + +T Q + +AG N
Sbjct: 146 -------------------AGATNRSNTNGNTDKNT-------QNGDVGDAGHN------ 173
Query: 363 EQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSV 422
E + DGP+ +N+ + +EN GNTS T + K V
Sbjct: 174 EDVAVVQEDGPQVAGSNNSTDNEDEIIENSCR----NEGNTSEITPQINSKRNGTKEAEV 229
Query: 423 GSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGG 482
+G D S+ +GN E ED G + G+ DS NN++ G
Sbjct: 230 TPG------TGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDS-SNNSKGQEG 282
Query: 483 SWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQK 542
+ G +D +D+ G+ + E+ P G ++ N+ + + +
Sbjct: 283 Q-DHGKEDDHDSSIGQNS------DSKEYYDPEGKED-------PHNEVDGDKTSKSEEN 328
Query: 543 GHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQA 602
+PE+ G+ + + + V + T + S + G P+ +
Sbjct: 329 SAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNI 388
Query: 603 VLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKN 662
+ + + G+ +K T ++ + P KS+ G + S N
Sbjct: 389 TKEVGKGNEGKEDKGQHGMILGKGNVK--TQGEVVNIEGPGQKSEPGNKVGHSNTGSDSN 446
Query: 663 SGGWGDAPSQSNQMKSGWGELSASTEWKDPKNT--GGWNDYKNNNSSNWGGGRPDEKTPS 720
S G+ M+ DP ++ ND N+ S N R D +
Sbjct: 447 SDGYDSYDFDDKSMQG-----------DDPNSSDESNGNDDANSESDNNSSSRGD----A 491
Query: 721 SWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEI 780
S+N + SKD G G S K ++ D T ++N S +G G G ++
Sbjct: 492 SYNSDESKDNGNG---------SDSKGAEDDDSDSTSDTNNSDS-----NGNGNNGNDDN 537
Query: 781 GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW 840
+G S +S D S +++ +S + ++ S
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS- 596
Query: 841 GGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDID-DGTSAWGDP 899
SNSS SS ++ + + S S S D D S D
Sbjct: 597 -----------DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS 645
Query: 900 NSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSW 959
NS + + NS + N S +SDS S D SD + S
Sbjct: 646 NSSDSSD------NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS 699
Query: 960 EEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLL 1019
E + ++ S S SS++++S S ++DS + + S+
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSS-------DSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 1020 SQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSG 1079
S + D+ S SD D + N D ND S +S ++DS
Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSD--SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810
Query: 1080 PYFEKGGSHGLFGNSTAQS 1098
+ S + ++ S
Sbjct: 811 DSSDSSDSDSSNSSDSSNS 829
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 87.4 bits (215), Expect = 1e-16
Identities = 194/963 (20%), Positives = 325/963 (33%), Gaps = 121/963 (12%)
Query: 157 GGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTT 216
G + +Y GSG SS++G GS + K + S T
Sbjct: 899 GSGQSPSYGRHGSGSGRSSSSGRH-------------GSGSGQSSGFGHKSSSGQSSGYT 945
Query: 217 DNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTE 276
+ S S G S + S + S+ +SSG+ + G S S S
Sbjct: 946 QHGSGS--GHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSG-------SRQSLGH 996
Query: 277 NNNGLGNWRNVS-GQDRIGPGSG-FSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSA 334
+G G+ ++ S + R G GSG S++ P + S W +S +G E+ + +SS
Sbjct: 997 GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW-------SSSRGPYESGSGHSS- 1048
Query: 335 QVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGM 394
G RE +S +++G S + H G +G ++S G
Sbjct: 1049 -----GLGHRESRSG-QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG--------QHGA 1094
Query: 395 PFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKERE 454
G + + + SQS+G + GS G G+ + S + +G+
Sbjct: 1095 SSGQSSSHGQHGSGS-SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1153
Query: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514
G+ + +S+G + ++ S+G Q S+ ++ G G+ +SG Q +
Sbjct: 1154 SGQHGSGLGESSG-----FGHHESSSG-------QSSSYSQHGSGSGHSSGYGQHGSRSG 1201
Query: 515 TGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQST 574
S + G SG + G+ Q + G+ +P GR GS +G S+
Sbjct: 1202 QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRH----GSGLGHSSS 1257
Query: 575 GSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVW 634
H +GS S + G R H ++ + + S +G +Q + +
Sbjct: 1258 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1317
Query: 635 DIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKS----GWGELSASTEWK 690
EG S + + + + S G+G + S Q S G G S+ +
Sbjct: 1318 GQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGS-GHSSSYG 1376
Query: 691 DPKNTGGWNDYKNNNSSNWGGGRP-DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGW 749
+ GW+ + S G SSW + G G G SS
Sbjct: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGH------SSSYEQH 1430
Query: 750 GEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNET 809
G Q+ S+S S +G+ G + G+G + S +
Sbjct: 1431 GSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGS-----------------GS 1473
Query: 810 GRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKD 869
G+ P+ +H P SG W P S SS SSG +
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSG-WSSSRGP-----YESGSSHSSGLGHRESRS 1527
Query: 870 EEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQG--GPAPREPNLPT 927
+ SG+ + S G+++ G +S + +S G G + +
Sbjct: 1528 GQSSGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 1586
Query: 928 PMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQ 987
S S Q G G P G G + + S H+ +S GQ
Sbjct: 1587 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQ 1646
Query: 988 GGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLS----VGSLSDKKFD 1043
+ G+ + + S G S+ E + SS S GS S +
Sbjct: 1647 SSSYS-----QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSG 1701
Query: 1044 VDKRAMNLGDFNDIMRKDRSGFRPPNSKDMG--------TTDSGPYFEKGGSHGLFGNST 1095
++ G + R G +S G ++ GPY + G +FG
Sbjct: 1702 HGRQGSGSGQSPS---RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1758
Query: 1096 AQS 1098
+ S
Sbjct: 1759 SGS 1761
Score = 87.4 bits (215), Expect = 1e-16
Identities = 220/1046 (21%), Positives = 358/1046 (34%), Gaps = 146/1046 (13%)
Query: 108 GQPPPPSCMLLGGGAGPPPCTAP-GANPNNAQVTGALLQSESGTAPDSTLGGAAASNYAN 166
GQ P PS G G+G +P G+ + G ESG++ S LG + + +
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPY---ESGSSHSSGLGHRESRSGQS 1530
Query: 167 STWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGS 226
S +G SS+ +S + H GS + +S +S + ++ GS
Sbjct: 1531 SGYGQHGSSSGHSSTHGQH--------GSTSGQ---SSSCGQHGASSGQSSSHGQHGSGS 1579
Query: 227 EKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWK---SDPKAKSVQSSNSTTENNNGLGN 283
+S+ G S G+ SG+ + + ++ S S ++G G+
Sbjct: 1580 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 1639
Query: 284 WRNVSGQD----RIGPGSGFSN-FNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVST 338
+ SGQ + G GSG S+ + + + S G S +G +S SS++
Sbjct: 1640 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRS--------GQSSRGERHGSSSRSSSRYGQ 1691
Query: 339 VGQTSREQQSK-MENAGVNFVVS-GREQAQIHNTDGPKNGNTNSLNLSSPNPMENKG--- 393
G SR+ + +G S GR + + ++ + S SS P E++
Sbjct: 1692 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHS 1751
Query: 394 MPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKER 453
FG + S+ +G S G G+ G S T G S++G + ++G+
Sbjct: 1752 SVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG-SSTGQSSSHGQHG 1810
Query: 454 EDSWKGASV-QKSTGS-KNDSWDNNNRSTGGSWNFGPQ------DSNDNKWGEGNKMTSG 505
S + +S Q+ +GS ++ S + +G S ++G S+ + G G+ +SG
Sbjct: 1811 SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG 1870
Query: 506 VSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSST 565
E S + G SG + G+ Q + + +G+ S +
Sbjct: 1871 FGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGS 1930
Query: 566 GSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQ 625
+G GS +G S S + GR +G GQ
Sbjct: 1931 RQSLGHGQHGSG--SGQSPSPSRGRH----------------------------GSGSGQ 1960
Query: 626 TQIKQDTVWDIEEVPRPEGKSDKGTEGWESA----ATQTKNSGGWGDAPSQSNQMKSGWG 681
+ G G+ GW S+ + + +S G G S+S Q SG+G
Sbjct: 1961 SS--------------SYGPYGSGS-GWSSSRGPYESGSGHSSGLGHRESRSGQ-SSGYG 2004
Query: 682 ELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKD--------QGWG 733
+ +S+ +T G + + SS+ G SS ++ S QG G
Sbjct: 2005 QHGSSS---GHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 2061
Query: 734 GGRQPNQGW---------SSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWG 784
G+ P G S G++G G + + G E + ++
Sbjct: 2062 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYS 2121
Query: 785 NGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPP 844
G+ S S G + RS + R +S + Q Q G G
Sbjct: 2122 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQ--HGSGSRQSSGHGRQGSGS 2179
Query: 845 PPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904
P R + S S S P S G ++Y+
Sbjct: 2180 GHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQ 2239
Query: 905 KNVNLWDKNSQG--GPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEE 962
SQG G + + S + S Q G G S G ++
Sbjct: 2240 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG------QQG 2293
Query: 963 EDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQT 1022
G + G GS S H S+S+GQ G+ W + + S G S
Sbjct: 2294 SGSGQSPSRGRHGSGSGH-SSSYGQ-----------HGSGSGWSSSSGRHGSGSGQSSGF 2341
Query: 1023 EDNPSSKMDLS----VGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDS 1078
+ SS S GS S ++ G + R +R G +S G S
Sbjct: 2342 GHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS---RGERHGSSSGSSSSYGQHGS 2398
Query: 1079 GPYFEKG-GSHGL-FGNSTAQSRGLH 1102
G G G HG G S + SRG H
Sbjct: 2399 GSRQSLGHGQHGSGSGQSPSPSRGRH 2424
Score = 84.0 bits (206), Expect = 1e-15
Identities = 196/941 (20%), Positives = 328/941 (34%), Gaps = 132/941 (14%)
Query: 119 GGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNG 178
G G+G P + G + + + + Q SG+ S+ G + + +S +G S +
Sbjct: 1706 GSGSGQSP--SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 1763
Query: 179 TSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
+S H GS + C + +S +++T + S+ G S + S+
Sbjct: 1764 SSAYSQH--------GSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 1814
Query: 239 KGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGN-WRNVSGQDRIGPGS 297
+ Q + SG + G S S +S++ +G G+ W + SG R G GS
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSG-------SGHSSSYGQHGSGSGWSSSSG--RHGSGS 1865
Query: 298 GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQ---SKMENAG 354
G S+ + S+W + G ++ G+ +S+ S GQ+SR +Q S ++
Sbjct: 1866 GQSSGFGHHESSSWQS---SGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSS 1922
Query: 355 VNFVVSGREQAQIHNTDGPKNGNTNSLNLS---SPNPMENKGMPFGMGLGNTSRSTDAPS 411
SG Q+ H G +G + S + S + + P+G G G +S S
Sbjct: 1923 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYES 1982
Query: 412 ----------------QSTGDRKTGSV-------GSWGAARGPS----------GTDTVS 438
QS+G + GS G G+A G S G +
Sbjct: 1983 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042
Query: 439 GQSNSGNNGNNGKEREDSWKGASV---QKSTGSKND-SWDNNNRSTGGSWNFGP------ 488
GQ SG++ ++G R+ S G S Q+ +GS+ S+ + +G S + G
Sbjct: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLG 2102
Query: 489 -------------QDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSST 535
Q S+ ++ G G+ +SG Q + S + G SG +
Sbjct: 2103 ESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQH 2162
Query: 536 GAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRP 595
G+ Q + G+ +P GR GS G S+ H +GS S + G R
Sbjct: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRH----GSGSGHSSSHGQHGSGSGRSSSRGPYESRS 2218
Query: 596 THPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIK------QDTVWDIEEVPRPEGKSDKG 649
H ++ + + S +G +Q + Q + +D +E S G
Sbjct: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD-QEGSSTGQSSSHG 2277
Query: 650 TEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNW 709
G S ++Q+ + G G QS S+ + + GW+ + S
Sbjct: 2278 QHG--SGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 2335
Query: 710 GGGRP-DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKP 768
G SSW + G G G SS G Q+ S+S
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGH------SSSYEQHGSRSGQSSRGERHGSSSGS 2389
Query: 769 VSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQ 828
S +G+ G + G+G + S +G+ P+ +H
Sbjct: 2390 SSSYGQHGSGSRQSLGHGQHGS-----------------GSGQSPSPSRGRHGSGSGQSS 2432
Query: 829 PPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMD 888
P SG W P S S SSG + + SG+ + S
Sbjct: 2433 SYSPYGSGSG-WSSSRGP-----YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2486
Query: 889 IDDGTSAWGDPNSYNYKNVNLWDKNSQG--GPAPREPNLPTPMTSKSASDSKSMQDGWGE 946
G+++ G +S + +S G G + + S S Q G G
Sbjct: 2487 GQHGSTS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
Query: 947 SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQ 987
P G G + + S H+ +S GQ
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQ 2586
Score = 83.2 bits (204), Expect = 2e-15
Identities = 190/962 (19%), Positives = 325/962 (33%), Gaps = 178/962 (18%)
Query: 157 GGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTT 216
G + NY GSG SS+N T GS + + + S +
Sbjct: 198 GSGQSPNYGQHGSGSGQSSSNDT-------------HGSGSGQSSGFSQHKSSSGQSSGY 244
Query: 217 DNNSASNPGSEKSTLPGSTTSNKGKGSQCQSAS----------SGNECNLGVWKSDPKAK 266
+ + + S GS + +G + +S+S SG+ +LG + ++
Sbjct: 245 SQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSR 304
Query: 267 SVQ--------SSNSTTENNNGLGNWRNVS-GQDRIGPG--SGFSNFNPNSNPSAWPALV 315
S +S++ +G G+ + S G G G SGF S S+ +
Sbjct: 305 QSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKH 364
Query: 316 QEGTSRKGALETDNSNSSAQVSTVGQ---TSREQQSKMENAGVNFVVSGREQAQIHNTDG 372
G+ + + + ++S Q S+ GQ +SR+ S ++ + SGR Q +
Sbjct: 365 GSGSGHSSS-QGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQS 423
Query: 373 PKNGNTNSLNLSSPNPMEN--------------KGMPFGMGLGNTSRSTDAPS----QST 414
P +G S + SP+ ++ G + G G+ S++ S +
Sbjct: 424 PGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
Query: 415 GDRKTGSVGSWGAARGPS----------GTDTVSGQSNSGNNGNNGKEREDSWKGASVQK 464
G + G G+ G S G+ + GQ SG+ + G R S G S
Sbjct: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
Query: 465 STG------SKNDSWDNNNRSTGGSWNFGPQDS-NDNKWGEGNKMT-SGVSQGEWKQPTG 516
S G ++ S+ + +G S + GP +S + + G G++ + SG S G + +
Sbjct: 544 SRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSS 603
Query: 517 SDELKI-----------------GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWG 559
S G SG + + G+ +Q + G+ Q+P G
Sbjct: 604 SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRG 663
Query: 560 RSSSSTG---------------------SEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHP 598
R S G V GQS+G HK+GS S + +H
Sbjct: 664 RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH- 722
Query: 599 DCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAAT 658
++G+ R G + E +
Sbjct: 723 ---------------------SSGY-----------------RKHGSRSGQSSRSEQHGS 744
Query: 659 QTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKT 718
+ S +G S S+Q SG G + + + G + +++ G G +
Sbjct: 745 SSGLSSSYGQHGSGSHQ-SSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803
Query: 719 PSSWNENPSKDQGWGGGRQ-PNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQ 777
+ + G+G QG+S + G Q ++ + +S SG +
Sbjct: 804 CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSS--SGQHDSSS 861
Query: 778 NEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQ----PPPPQ 833
+ ++G +AS + G R + +G+ P + Q P +
Sbjct: 862 GQSSSYGQHESASHHASG------RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGR 915
Query: 834 PEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGT 893
+SG G G S+S SSG S +E+ +S G+
Sbjct: 916 SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGS 975
Query: 894 SAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQ--------DGWG 945
S+ G +SY G P+P + S S GW
Sbjct: 976 SS-GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWS 1034
Query: 946 ESDGPV-TGARHPS--WEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNN 1002
S GP +G+ H S E G + G GS+S H S++ GQ G + S G +
Sbjct: 1035 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH-SSTHGQHGSTSGQSSSCGQHG 1093
Query: 1003 DS 1004
S
Sbjct: 1094 AS 1095
Score = 76.6 bits (187), Expect = 2e-13
Identities = 162/727 (22%), Positives = 271/727 (37%), Gaps = 126/727 (17%)
Query: 119 GGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNG 178
G G+G P + G + + + + + Q SG+ S+ G + + +S +G S +
Sbjct: 2176 GSGSGHSP--SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233
Query: 179 TSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
+S H GS + C + +S +++T + S+ G S + S+
Sbjct: 2234 SSAYSQH--------GSGSGHF-CSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 2284
Query: 239 KGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGN-WRNVSGQDRIGPGS 297
+ Q + SG + G S S +S++ +G G+ W + SG R G GS
Sbjct: 2285 QSSSYGQQGSGSGQSPSRGRHGSG-------SGHSSSYGQHGSGSGWSSSSG--RHGSGS 2335
Query: 298 GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQ---SKMENAG 354
G S+ + S+W + G ++ G+ +S+ S GQ+SR ++ S ++
Sbjct: 2336 GQSSGFGHHESSSWQS---SGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 2392
Query: 355 VNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQST 414
SG Q+ H G +G SP+P + G G G QS+
Sbjct: 2393 YGQHGSGSRQSLGHGQHGSGSGQ-------SPSPSRGR---HGSGSG----------QSS 2432
Query: 415 GDRKTGSVGSWGAARGP----SGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKN 470
GS W ++RGP SG + G S + ++G + S G S ST ++
Sbjct: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS---STHGQH 2489
Query: 471 DSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQ 530
S + S G Q S+ + G G+ +SG +Q +GS G+ G Q
Sbjct: 2490 GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG----RQGSGS-----GQSPGHGQ 2540
Query: 531 PNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHN--- 587
S G+ Q+P +GR S +G GS S H+
Sbjct: 2541 RGS-----------------GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESS 2583
Query: 588 SGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSD 647
SG+ S H ++G+GQ + E G S
Sbjct: 2584 SGQSSSYSQHGSGSG----------------HSSGYGQHGSRSGQSSRGERHGSSSGSSS 2627
Query: 648 K-GTEGWESAATQTKNSGGWGDAPSQS-NQMKSGWGELSASTEWKDPKNTG-----GWND 700
G G S + Q+ G G QS ++ + G G +S+ + +G G +
Sbjct: 2628 HYGQHG--SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 2685
Query: 701 YKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSN 760
+ +SS +G S+++++ G G G +QG +G DQ +S
Sbjct: 2686 SRLGHSSVFGQHESGSGHSSAYSQH-----GSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2740
Query: 761 WESSA-------SKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQP 813
+SS+ S SG+G G G+G + S G S + +G
Sbjct: 2741 GQSSSYGHRGSGSSQSSGYGRHGA------GSGQSLSHGRHGSGSGQSSSYGQHGSGSGQ 2794
Query: 814 NSWNKQH 820
+S QH
Sbjct: 2795 SSGYSQH 2801
Score = 74.3 bits (181), Expect = 9e-13
Identities = 187/910 (20%), Positives = 321/910 (35%), Gaps = 106/910 (11%)
Query: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206
ESG+ S LG + + +S +G SS+ +S + H + + C
Sbjct: 575 ESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQH-------GSTSGQSSSCGQHG 627
Query: 207 DTESSSENTTDNNSASNPGS---EKSTLPGSTTSNKGKGSQCQSASSGNECNLGV-WKSD 262
T S + + S S+ S ++ + G + S GS +SS + G W S
Sbjct: 628 ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS- 686
Query: 263 PKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRK 322
S S + ++G G+ ++ SGQ SG+S S+ S+ G +
Sbjct: 687 ----SNGPHGSVSGQSSGFGH-KSGSGQS-----SGYSQHGSGSSHSS-------GYRKH 729
Query: 323 GALETDNSNSSAQVSTVGQTSREQQS-----KMENAGVNFVVSGREQAQI-------HNT 370
G+ +S S S+ G +S Q + G SG +++ H++
Sbjct: 730 GSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSS 789
Query: 371 DGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNT----------SRSTDAPSQSTGDRKTG 420
++G+ S + S + G G G + S S SQ +G
Sbjct: 790 SHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSG 849
Query: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASV---QKSTGS-KNDSWDNN 476
S G SG + GQ S ++ +G+ R S G S Q+ +GS ++ S+ +
Sbjct: 850 QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909
Query: 477 NRSTGGSWNFGPQDSNDNKW-GEGNKMTSGVSQGEWKQPTGSDEL--------KIGEWSG 527
+G S + G S + G G+K +SG S G + +GS + G+ S
Sbjct: 910 GSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969
Query: 528 PNQPNSSTGAWDNQKGHPLPENQ---------GNAQAPCWGRSSSSTGSEVGGQSTGSNH 578
Q SS+G+ + H Q G+ Q+P R +GS G S+ +
Sbjct: 970 SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS--GQSSSYGPY 1027
Query: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638
++GS S + G H ++ ++ + S++G T + +
Sbjct: 1028 RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS 1087
Query: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGW 698
G S + + + S G+G S S Q G G+ + + G
Sbjct: 1088 SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ-SPGHGQRGSGSRQSPSYGRHGS 1146
Query: 699 NDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKN 758
++++S G G E + +E+ S G SSG G Q+
Sbjct: 1147 GSGRSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 1205
Query: 759 SNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNK 818
S+S S +G+ G + G+G +G S + +G +S +
Sbjct: 1206 GERHGSSSGSSSHYGQHGSGSRQSSGHG------RQGSGSGHSPSRGRHGSGLGHSSSHG 1259
Query: 819 QHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGW--- 875
QH P SG +V + S SG A + SG
Sbjct: 1260 QHGSGSGRSSSRGPYESRSGH---------SSVFGQHES-GSGHSSAYSQHGSGSGHFCS 1309
Query: 876 EEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQG------GPAPREPNLPTPM 929
+ + + D S+ G +SY ++ + G G +P +
Sbjct: 1310 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGS 1369
Query: 930 TSKSASDSKSMQDGWGESDG-PVTGARHPSWEEEEDGGVWNTTG--SQGSASSHNSASWG 986
S+ GW S G +G+ S + W ++G GS S H S+S+
Sbjct: 1370 GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGH-SSSYE 1428
Query: 987 QGGKKQMKCS 996
Q G + + S
Sbjct: 1429 QHGSRSGQSS 1438
Score = 72.0 bits (175), Expect = 5e-12
Identities = 208/1012 (20%), Positives = 340/1012 (33%), Gaps = 218/1012 (21%)
Query: 108 GQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANS 167
GQ P PS G G+G P + + + ESG+ S LG + + +S
Sbjct: 1004 GQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRG--PYESGSGHSSGLGHRESRSGQSS 1061
Query: 168 TWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSE 227
+G SS+ +S + H GS +S ++++ ++ G
Sbjct: 1062 GYGQHGSSSGHSSTHGQH--------GS--------------TSGQSSSCGQHGASSGQS 1099
Query: 228 KSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNV 287
S + S++ G Q + SG G + S S + +G G+ R+
Sbjct: 1100 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHG-------QRGSGSRQSPSYGRHGSGSGRSS 1152
Query: 288 SGQDR---IGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSR 344
S +G SGF + +S S+ S+ G+ +S S GQ+SR
Sbjct: 1153 SSGQHGSGLGESSGFGHHESSSGQSS-------SYSQHGSGSGHSSGYGQHGSRSGQSSR 1205
Query: 345 EQQSKMENAGVNFVV---SGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLG 401
++ + + SG Q+ H G +G++ S G GLG
Sbjct: 1206 GERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRH------------GSGLG 1253
Query: 402 NTSRSTDAPSQSTGDRKTGSVGSWGAARGP----SGTDTVSGQSNSGNNGNNGKEREDSW 457
++S S G +GS S ++RGP SG +V GQ SG+ ++ + S
Sbjct: 1254 HSS--------SHGQHGSGSGRS--SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 1303
Query: 458 KGASVQK----STGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQ 513
G + ST ++ ++D STG S ++G + S ++ + +G Q +
Sbjct: 1304 SGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRG 1363
Query: 514 PTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSST-------- 565
GS G S Q S +G W + G G+ Q+ +G SS+
Sbjct: 1364 RHGSGS---GHSSSYGQHGSGSG-WSSSSGR---HGSGSGQSSGFGHHESSSWQSSGCTQ 1416
Query: 566 --------------GSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRT 611
GS G S G H + S S + G+ + ++
Sbjct: 1417 HGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1476
Query: 612 DLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAA----TQTKNSGGWG 667
R +G GQ+ P G GW S+ + + +S G G
Sbjct: 1477 PSPSRGRHGSGSGQSSSYS-----------PYGSGS----GWSSSRGPYESGSSHSSGLG 1521
Query: 668 DAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPS 727
S+S Q SG+G+ +S+ +T G + + SS+ G SS ++ S
Sbjct: 1522 HRESRSGQ-SSGYGQHGSSS---GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 1577
Query: 728 KD--------QGWGGGRQPNQGW---------SSGKNGWGEEVDQTKNSNWESSASKPVS 770
QG G G+ P G S G++G G ++ +S S S
Sbjct: 1578 GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS--GRSSSSGQHGSGLGESS 1635
Query: 771 GWG--EGGQNEIGTWGNGGNASLASKGGWEDCKRS---PAWNETGRQPNSWNKQHQQQQP 825
G+G E + ++ G+ S S G + RS G S ++ Q
Sbjct: 1636 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSG 1695
Query: 826 PQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWS------------------SGPQPATP 867
+Q + SGS P G+ +SS SG
Sbjct: 1696 SRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1755
Query: 868 KDEEPSGWEEPSPQSIS----------------RKMDIDDGTSAWGDPNSYNYKNVNLWD 911
+ E SG Q S + D S+ G +S+
Sbjct: 1756 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQ 1815
Query: 912 KNSQG------GPAPREPNLPTPMTSKSASDSKSMQDGW-------GESDGPVTGARH-- 956
+S G G +P + S+ GW G G +G H
Sbjct: 1816 SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE 1875
Query: 957 -------------------PSWEEEEDGGVWNTTGSQGSASSHNSASWGQGG 989
S+E+ ++ G Q +SS +S+S+GQ G
Sbjct: 1876 SSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG 1927
Score = 71.6 bits (174), Expect = 6e-12
Identities = 149/721 (20%), Positives = 250/721 (34%), Gaps = 68/721 (9%)
Query: 411 SQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNS--GNNGNNGKEREDSWKGASVQKSTGS 468
S S R + G+ +R S SGQ NS G + + G++ DS + +S + GS
Sbjct: 139 SYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQ-SSGRGQCGS 197
Query: 469 KNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGP 528
+ N + GS G SND G G+ +SG SQ + S + G SG
Sbjct: 198 GSGQSPNYGQHGSGS---GQSSSNDTH-GSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGH 253
Query: 529 NQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNS 588
+ G+ Q + + +G+ S + +G GS + S +
Sbjct: 254 SSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHG 313
Query: 589 GRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEG-KSD 647
+ +H + SR + +G+GQ + + G S
Sbjct: 314 SGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSS 373
Query: 648 KGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSS 707
+G G S + Q +SG G + QS S +G+ +++ +++ G + + +
Sbjct: 374 QGQHG--STSGQASSSGQHGSSSRQS----SSYGQHESAS-----RHSSGRGQHSSGSGQ 422
Query: 708 NWGGGRPDEKTPSSWNENPSKDQ-GWGGGRQPNQG----WSSGKNGWGEEVDQTKNSN-- 760
+ G G + S ++PS Q G G GR + G S +G+G +++S+
Sbjct: 423 SPGHG----QRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGY 478
Query: 761 -WESSASKPVSGWGE---------GGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETG 810
S S SG G+ G+ + + G+ + G + S + +G
Sbjct: 479 TQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSG 538
Query: 811 RQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDE 870
+ P+ +H+ P SG P S S SSG +
Sbjct: 539 QSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGP------YESGSGHSSGLGHQESRSG 592
Query: 871 EPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMT 930
+ SG+ + S G+++ G +S +S G
Sbjct: 593 QSSGYGQHGSSSGHSSTHGQHGSTS-GQSSSCGQHGATSGQSSSHGQHG----------- 640
Query: 931 SKSASDSKSMQDGWGESDGPVTGARH-------PSWEEEEDGGVWNTT-GSQGSASSHNS 982
S S+ S+ Q G G P G RH S+ + G W+++ G GS S +S
Sbjct: 641 SGSSQSSRYGQQGSGSGQSPSRG-RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSS 699
Query: 983 ASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSK-MDLSVGSLSDKK 1041
+ G Q + G+ S + K S G S++E + SS + S G
Sbjct: 700 GFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGS 759
Query: 1042 FDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGL 1101
+ R G +S G SG H G+ A G
Sbjct: 760 HQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQ 819
Query: 1102 H 1102
H
Sbjct: 820 H 820
Score = 66.6 bits (161), Expect = 2e-10
Identities = 157/782 (20%), Positives = 262/782 (33%), Gaps = 72/782 (9%)
Query: 249 SSGNECNLGVWKSDPKAKSVQSS--NSTTENNNGLGNWRNVSGQDRI--GPGSGFSNFNP 304
SS + + ++D +++V+ S T + L R+ SGQ G S + N
Sbjct: 125 SSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNS 184
Query: 305 NSNPSAWPALVQEGTSRK------GALETDNSNSSAQVSTVGQTSREQQSKM---ENAGV 355
+S+ S+ G+ + G+ +S++ S GQ+S Q K +++G
Sbjct: 185 DSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGY 244
Query: 356 NFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTG 415
+ SG + + G ++G ++ G RS+ S S G
Sbjct: 245 SQHGSGSGHSSGYGQHGSRSGQSSR--------------------GERHRSSSGSSSSYG 284
Query: 416 DRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDN 475
+GS S G R SG+ G+ + G+S S G +S
Sbjct: 285 QHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRG-HYESGSG 343
Query: 476 NNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSST 535
G + Q S +K G G+ +S SQG+ +G G+ ++ +SS
Sbjct: 344 QTSGFGQHESGSGQSSGYSKHGSGSGHSS--SQGQHGSTSGQAS-SSGQHGSSSRQSSSY 400
Query: 536 GAWDNQKGHPLPENQ---GNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRS 592
G ++ H Q G+ Q+P G+ S +G G+ SS
Sbjct: 401 GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSG 460
Query: 593 YRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEG 652
Y ++ + T ++G GQ + G+S +G
Sbjct: 461 YSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSR-------------SGQSSRGERQ 507
Query: 653 WESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDP---KNTGGWNDYKNNNSSNW 709
SA +S +G S S Q S S + P ++ G + +
Sbjct: 508 GSSAG----SSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGY 563
Query: 710 GGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPV 769
G GR + P E+ S G ++ G SSG G + S S
Sbjct: 564 GSGRSSSRGP---YESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 620
Query: 770 SGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQP 829
S G+ G + +G + S +S+ + S + R + + H
Sbjct: 621 SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGS 680
Query: 830 PPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDI 889
++G G G S S SSG SG+ + +S
Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740
Query: 890 DDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMT--SKSASDSKSMQDGWGES 947
G+S+ G +SY + G + P+ + S S S Q G G S
Sbjct: 741 QHGSSS-GLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTS 799
Query: 948 DGP-----VTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNN 1002
+G+ S + + G GSAS H S S G+ G + S G ++
Sbjct: 800 CSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFS-SQGRHGSTSGQSSSSGQHD 858
Query: 1003 DS 1004
S
Sbjct: 859 SS 860
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 83.6 bits (205), Expect = 2e-15
Identities = 195/955 (20%), Positives = 303/955 (31%), Gaps = 186/955 (19%)
Query: 107 RGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPD-------STLGGA 159
RG P + G P NPN GA + T P TL GA
Sbjct: 917 RGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLPGA 976
Query: 160 AASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNN 219
NS S A + T + +V S E P +K +S+ +
Sbjct: 977 RNKVKGNSNVVSKAGAREDTMGSA----QPQVVANSQRETLPGARNKVKGNSNAISKAEA 1032
Query: 220 SASNPGS---------EKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270
A GS + LPG+ +G + A +G + V + P+A +
Sbjct: 1033 GAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADT---VGSAQPQAVANSQ 1089
Query: 271 SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALV--QEGTSRKGALETD 328
S + N + N + G G+G + SA P +V +G + GA +
Sbjct: 1090 SETLLGARNKVKG--NTIAVPKAGTGAG-------TRHSAQPQIVAGSQGETLPGARDKS 1140
Query: 329 NSNSSAQVSTVGQTSREQQSKM-----ENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNL 383
S S A+ + + + +++ G + Q IH D NG +
Sbjct: 1141 MSTSEAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIH--DYYWNGIGVEDWI 1198
Query: 384 SSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSG---TDTVSGQ 440
++ ++ + N+ D D S+GSW A +G + V+
Sbjct: 1199 AAERWIKFRFQTMDGDWENSVSWAD-------DENEASIGSWSGASDKAGIIRSWAVACD 1251
Query: 441 SNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGN 500
S SW GA + G G+W + ++ W G
Sbjct: 1252 ETSVK----------SWAGARAENVVGI-------------GTWARAGEQASGGLWAGGQ 1288
Query: 501 KMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGR 560
S+G W D+ G W+G +S G+W L NQ A W
Sbjct: 1289 -----TSEGTW----AGDKASGGAWTGAEN-QASGGSW------ALAGNQ--AIGELWAA 1330
Query: 561 SSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSN 620
+S GS GGQ++G + + + + + +S V+
Sbjct: 1331 GQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQ 1390
Query: 621 TGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESA-ATQTKNSGGWGDAPSQSNQMKSG 679
G G W G SD+ G + Q G W A Q+ SG
Sbjct: 1391 AGGGS--------W--------AGTSDQSGGGSKPRFEDQASGEGSWAGAGGQA----SG 1430
Query: 680 WGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPN 739
L +D + W D + S G D+ + +W + G R N
Sbjct: 1431 GSMLGP----EDQSSGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFEN 1486
Query: 740 Q-----GWSS--GKNGWGEEV---DQTKNSNWESSASKPVSGWGEG--GQNEIGTWGNGG 787
Q W+ G+ G G +V DQ+ +W +S + G+ G Q G+W G
Sbjct: 1487 QTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAG 1546
Query: 788 NAS-----------LASKGGWEDCKRS---------------PAWNETGRQPNSWNKQHQ 821
+ + ++ +G W D + +W TG Q + W
Sbjct: 1547 HPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVC- 1605
Query: 822 QQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQ 881
P GSWGG G RP ++ SS W+ P Q
Sbjct: 1606 ---------PGSQTNGGSWGGASGQDVGGSRPGPTNQSSA-----------GSWDSPGSQ 1645
Query: 882 SISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQ 941
+ T A + D+ GG P + + + D S
Sbjct: 1646 -----VSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGI 1700
Query: 942 DGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCS 996
WG + G V G P ++ GG W TG+Q S SW G + + CS
Sbjct: 1701 GSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQSS-----GRSWIGPGDQAVDCS 1750
Score = 68.6 bits (166), Expect = 5e-11
Identities = 176/812 (21%), Positives = 286/812 (35%), Gaps = 115/812 (14%)
Query: 122 AGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGG--AAASNYANSTWGSGASSNNGT 179
AG T PGA + + A TA D A A + S GSG + T
Sbjct: 1126 AGSQGETLPGARDKSMSTSEA-----EATAEDEAYAKPEAEAMPTSESEGGSGTQACRKT 1180
Query: 180 SPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDN---NSASNPGSEKSTLPGSTT 236
PN IH + +G +E+W IA++ T D NS S E GS +
Sbjct: 1181 QPN-IHDY---YWNGIGVEDW--IAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWS 1234
Query: 237 SNKGKGSQCQS-ASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGP 295
K +S A + +E ++ W + + EN G+G W Q G
Sbjct: 1235 GASDKAGIIRSWAVACDETSVKSW-----------AGARAENVVGIGTWARAGEQASGGL 1283
Query: 296 GSGFSNFN-----PNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350
+G ++ AW + + AL + + ++ GQ S
Sbjct: 1284 WAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALA--GNQAIGELWAAGQASDGSWPGG 1341
Query: 351 ENAGVNFV---------VSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLG 401
+ +GV++V QA + G GN +S++ + + G G G
Sbjct: 1342 QASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGG---GSWAG 1398
Query: 402 NTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGAS 461
+ +S D+ +G GSW A G + ++ G + + SW +
Sbjct: 1399 TSDQSGGGSKPRFEDQASGE-GSWAGAGGQASGGSMLGPEDQSSG--------RSWADTA 1449
Query: 462 VQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELK 521
Q S GS+ D +S+GG+W G D + G S+ ++ T +
Sbjct: 1450 DQASGGSRLGHVD---QSSGGAW-AGTLD-----------QSGGGSKPRFENQTTEE--- 1491
Query: 522 IGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEV-GGQSTGSNHKA 580
G W+G G PE+Q + GRS +++G ++ GG G +A
Sbjct: 1492 -GSWAG-------AGGQAGGGSKVGPEDQSS------GRSWANSGDQISGGFLVGIVDQA 1537
Query: 581 GSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVP 640
+G + P + + S D +V+ ++ G W
Sbjct: 1538 NGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSW------ 1591
Query: 641 RPEGKSDKGTEGWESAATQTKNSGG-WGDAPSQS-NQMKSGWGELSASTEWKDPKNTGGW 698
G D+ + GW ++ +GG WG A Q + G S++ W P +
Sbjct: 1592 --AGTGDQAS-GWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSG 1648
Query: 699 NDYKNNNSSNWGGG--RP--DEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754
+ + + + GG +P +++ + DQ GG R ++ SSG WG
Sbjct: 1649 SCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGG 1708
Query: 755 QTKNSNWESSASKPVSG-W-GEGGQNEIGTW-GNGGNASLASKGGWED-CKRSPAWNETG 810
Q A + G W G G Q+ +W G G A SK +ED +W G
Sbjct: 1709 QVLGGARPGPADQSSGGSWAGTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAG 1768
Query: 811 RQPN--SW--NKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT 866
Q + SW ++ + + GSW G + S ++
Sbjct: 1769 SQASGESWAGSRPGNEAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFG 1828
Query: 867 PKDEEPSG---WEEPSPQSISRKMDIDDGTSA 895
P E G W E +SR D D+ T+A
Sbjct: 1829 PGAEAVIGSWCWTEEKADIVSRPDDKDEATTA 1860
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 75.5 bits (184), Expect = 4e-13
Identities = 139/608 (22%), Positives = 228/608 (37%), Gaps = 85/608 (13%)
Query: 225 GSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNW 284
GS +S+ G S G+ S Q +S ++ + + S + + G G +
Sbjct: 599 GSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQY 658
Query: 285 RNVSGQDR--------IGPGSGFSNFNPNSNPSAWPALVQEGT-SRKGALETDNSNSSAQ 335
+ SGQ G SGF S S++ Q G S + + + +SS Q
Sbjct: 659 GSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYG---QHGFGSSQSSGYGQHGSSSGQ 715
Query: 336 VSTVGQ--TSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTN------SLNLSSPN 387
S GQ S Q S G SG Q+ G +G ++ S + S
Sbjct: 716 TSGFGQHELSSGQSSSFGQHG-----SGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770
Query: 388 PMENKGMPFGMGLG-NTSRSTDAPSQ-STGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
+ G G G + SR T Q +G ++ G +G+ G S G S SG
Sbjct: 771 GQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHG-SGSGQ 829
Query: 446 NGNNGKEREDSWKGASVQKSTGSKNDS-WDNNNRSTGGSWNFGPQDSNDNKW-GEGNKMT 503
+ G+ S + + Q +GS S + + S+G + FG S+ ++ G G +
Sbjct: 830 SSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGS 889
Query: 504 -SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSS 562
SG S G + TGS G++SG Q S + +Q + G++Q+ +G+
Sbjct: 890 GSGQSSGFGQHGTGS-----GQYSGFGQHESRS----HQSSYG-QHGSGSSQSSGYGQHG 939
Query: 563 SSTGSEVG--------GQSTG-SNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDL 613
SS+G G GQS+G H +GS S G+ ++ S+++
Sbjct: 940 SSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNY 999
Query: 614 DPR---VLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAP 670
++G+GQ G S T G+ + + G+G
Sbjct: 1000 GQHGSGSSQSSGYGQ-----------------HGSSSGQTTGFGQHRSSSGQYSGFGQHG 1042
Query: 671 SQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSN----WGGGRPDEKTPSSWNENP 726
S S+Q SG+G+ + + G+ Y++ + + G G N
Sbjct: 1043 SGSDQ-SSGFGQHGTGS-----GQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNS 1096
Query: 727 SKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE----GGQNEIGT 782
+ G+G R P G SSG +G Q+ S + SG+ + GQ+ G
Sbjct: 1097 GQTSGFGQHR-PGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQ 1155
Query: 783 WGNGGNAS 790
G G + S
Sbjct: 1156 HGTGSSQS 1163
Score = 66.2 bits (160), Expect = 3e-10
Identities = 191/889 (21%), Positives = 295/889 (33%), Gaps = 146/889 (16%)
Query: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTS 180
G P C P +NP + + + P + G + +S G S + +
Sbjct: 332 GGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSC 391
Query: 181 PNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKG 240
N H + + + SSS N GS +ST + G
Sbjct: 392 SNGQHEYGS--------------CGRFSNSSSSNEFSKCDQYGSGSSQST----SFEQHG 433
Query: 241 KGSQCQSASSGNECNLGVWKSDPKAKSVQS-----SNSTTENNNGLGNWRNVSGQDRIGP 295
G S + C G ++ S QS S++ +G G + SGQ
Sbjct: 434 TGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQS---- 489
Query: 296 GSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGV 355
SGF S S+ G + G++ +S S GQ+S Q + +
Sbjct: 490 -SGFGQCGSGSGQSS-------GFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQS 541
Query: 356 NFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGM-GLGNTSRSTDAPSQST 414
++ G +G++ S E G FG GLG+ QST
Sbjct: 542 SYGQHG-------------SGSSQSSGYGQYGSRETSG--FGQHGLGS--------GQST 578
Query: 415 GDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASV--QKSTGSKNDS 472
G G +G+ SG + GQ SG+ ++G + +S G S Q S+GS S
Sbjct: 579 G------FGQYGSG---SGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSS 629
Query: 473 W--DNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQ 530
+ +R T G G S +G+ SG S G + +GS G+ SG Q
Sbjct: 630 GYGQHGSRQTSGFGQHGSGSSQSTGFGQYGS-GSGQSSGFGQHVSGS-----GQSSGFGQ 683
Query: 531 PNSSTGAWD-NQKGHPLPENQGNAQAPCWGRSSSSTGSEVG-GQSTGSNHKAGSSDSHNS 588
S +G Q G G++Q+ +G+ SS+G G GQ S+ ++ S H S
Sbjct: 684 HESRSGHSSYGQHGF------GSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGS 737
Query: 589 G--RRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKS 646
G + S H ++G+GQ + + + S
Sbjct: 738 GSGQSSGFGQHGSGSG----------------QSSGFGQHESRSGQSSYGQHSSGSSQSS 781
Query: 647 DKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNS 706
G G + QT G G SQS +G+G+ + + + G+ + + +
Sbjct: 782 GYGQHG----SRQTSGFGQHGSGSSQS----TGFGQYGSGSG-----QSAGFGQHGSGSG 828
Query: 707 SNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSAS 766
+ G G+ + ++ S S Q G Q SSG G QT S+S
Sbjct: 829 QSSGFGQHESRSHQS-----SYGQHGSGSSQ-----SSGYGQHGSSSGQTSGFGQHRSSS 878
Query: 767 KPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPP 826
SG+G+ G G+G ++ G +E+ +S+ QH
Sbjct: 879 GQYSGFGQHGS------GSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYG-QHGSGSSQ 931
Query: 827 QQPPPPQPEASGSWGGPPPPPPGNVRPS---NSSWSSGPQPATPKDEEPSGWEEPSPQSI 883
+SG G G+ + S SG + E SG Q
Sbjct: 932 SSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHE 991
Query: 884 SRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDG 943
SR + G G S Y Q G + + S S S Q G
Sbjct: 992 SRSSQSNYGQHGSGSSQSSGY---------GQHGSSSGQTTGFGQHRSSSGQYSGFGQHG 1042
Query: 944 WGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQ 992
G G + G + + Q S H S S G Q
Sbjct: 1043 SGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQ 1091
Score = 55.1 bits (131), Expect = 6e-07
Identities = 136/677 (20%), Positives = 241/677 (35%), Gaps = 75/677 (11%)
Query: 145 QSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIA 204
+ ES T D S Y +S+W G +G S G C
Sbjct: 110 EEESETEEDEEDTPGHKSGYRHSSWSEG--EEHGYS------------SGHSRGTVKCRH 155
Query: 205 SKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
++ ++S + GS+K S+ + G + + SS E + KS
Sbjct: 156 GSNSRRLGRQGNLSSSGNQEGSQKR-YHRSSCGHSWSGGKDRHGSSSVELRERINKSHIS 214
Query: 265 AKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQE---GTSR 321
+ S E+ +G +W G + G S NS S ++E G+S
Sbjct: 215 PS--RESGEEYESGSGSNSWER-KGHGGLSCGLETSGHESNSTQSR----IREQKLGSSC 267
Query: 322 KGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSL 381
G+ ++ + + S R Q + F G + + I ++G + +
Sbjct: 268 SGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYI------QSGCQSGI 321
Query: 382 NLSSPNPMENKGMPFGMGLGNTSRSTDAPSQ-STGDRKTGSVGSWGAA-RGPSGTDTVSG 439
+ + G P G G ++ + + SQ G R+ G + G R S + G
Sbjct: 322 KGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCG 381
Query: 440 QSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEG 499
Q SG + + + + G+ + S S ++ + ++ GS Q ++ + G G
Sbjct: 382 QYGSGGSQSCSNGQHEY--GSCGRFSNSSSSNEFSKCDQYGSGS----SQSTSFEQHGTG 435
Query: 500 NKMTSGVSQGEWK--QPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPC 557
+SG Q Q G E + G +Q SS+G H Q + C
Sbjct: 436 LSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQC 495
Query: 558 WGRSSSSTG----SEVGGQSTG-SNHKAGSSDSHNSGR---RSYRPTHPDCQAVLQTLLS 609
S S+G V GQS+G H + S S G+ RS + ++ +
Sbjct: 496 GSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSG 555
Query: 610 RTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDA 669
R +G+GQ + + G+S G+ + + S G+G
Sbjct: 556 YGQYGSR--ETSGFGQHGLGSGQSTGFGQYGSGSGQS----SGFGQHGSGSGQSSGFGQH 609
Query: 670 PSQSNQMKSGWGELSASTEWKD------PKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWN 723
S+S Q S +G+ S+ + + T G+ + + +S + G G+ + S
Sbjct: 610 ESRSGQ--SSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSG 667
Query: 724 -----ENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE---- 774
+ G+G + S G++G+G Q+ S+S SG+G+
Sbjct: 668 FGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGS--SQSSGYGQHGSSSGQTSGFGQHELS 725
Query: 775 -GGQNEIGTWGNGGNAS 790
G + G G+G S
Sbjct: 726 SGQSSSFGQHGSGSGQS 742
Score = 49.7 bits (117), Expect = 2e-05
Identities = 141/715 (19%), Positives = 242/715 (33%), Gaps = 85/715 (11%)
Query: 121 GAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWG---SGASSNN 177
G+G + G + +++ T Q SG+ S G + + +S +G SG+ ++
Sbjct: 926 GSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSS 985
Query: 178 GTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTS 237
G + + SS + T S+ G + S
Sbjct: 986 GFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGS 1045
Query: 238 NKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGS 297
++ G SG G ++S + S S + ++G G + SGQ S
Sbjct: 1046 DQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQT-----S 1100
Query: 298 GFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNF 357
GF P S S+ G + G+ +S S G++S Q +
Sbjct: 1101 GFGQHRPGSGQSS-------GFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYR------ 1147
Query: 358 VVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDR 417
SG+ H T G++ S FG + + + + +
Sbjct: 1148 --SGQSSYGQHGT-----GSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSG 1200
Query: 418 KTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNN 477
++ G +G+ G S T G+S +G+ R+++ G ++ +T + S +
Sbjct: 1201 QSTGFGQYGSGSGQS-TGLGQGESQQVESGSTVHGRQETTHGQTI--NTTRHSQSGQGQS 1257
Query: 478 RSTGGSWNFGPQDS-NDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTG 536
TG + S ++N E + S GS K G Q G
Sbjct: 1258 TQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQ-----G 1312
Query: 537 AWDNQKGHPLPE-NQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNS-GRRSYR 594
Q+G + G+ Q S+ TGS G+ S+ A S+ H+ R +
Sbjct: 1313 TTHGQRGDTTRHGHSGHGQ-------STQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHS 1365
Query: 595 PTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWE 654
QA Q S + + R T +GQT G G
Sbjct: 1366 QEQTHSQAGSQHGESESTVHER--HETTYGQT-------------GEATGHGHSGHGQST 1410
Query: 655 SAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRP 714
++T G G + S +++ SG S E T G ++ S + GR
Sbjct: 1411 QRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQE-----QTHGQAGSQHGESGSTVHGR- 1464
Query: 715 DEKTPSSWNENPSKDQGWGGGRQPNQGWS-SGKNGWGEEVDQTKNSNWESSASKPVSGWG 773
T + ++ + G+ +G S +G+ G G ++ +S S S SG
Sbjct: 1465 -HGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGH--SESSDSEVHSGGSHTHSGHT 1521
Query: 774 EG------GQNEI-------GTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNS 815
G G++E T G G+ + S G E ++ + TGRQ S
Sbjct: 1522 HGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGS-RTTGRQRTS 1575
Score = 47.0 bits (110), Expect = 2e-04
Identities = 83/418 (19%), Positives = 148/418 (35%), Gaps = 65/418 (15%)
Query: 194 GSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASS--- 250
GS E I + ++ T D + S G +ST GS+T+ + + +S+ S
Sbjct: 1830 GSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVH 1889
Query: 251 --GNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNP 308
G+ + G S +++ +S ++ + + + GQ G + +P+
Sbjct: 1890 SGGSHTHSGHTHSQARSQHGESESTVHKRH------QTTHGQT----GDTTEHGHPSHGQ 1939
Query: 309 SAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIH 368
+ +Q G+ G + +S S G + AG ++ SG + +H
Sbjct: 1940 T-----IQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESG---SSVH 1991
Query: 369 NTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTG------SV 422
G +G T G +ST S++TG R +G S
Sbjct: 1992 ERHGTTHGQTADTTRH--------------GHSGHGQSTQRGSRTTGRRASGHSEYSDSE 2037
Query: 423 GSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRS--T 480
G G + SG S G +G++ ER + G + + + + + R T
Sbjct: 2038 GHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRT 2097
Query: 481 GGSWNFGPQDSNDNKWGEGNKMT-SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWD 539
G G +S+D++ G T SG + G+ + G I G +
Sbjct: 2098 AGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRH 2157
Query: 540 NQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTH 597
Q GH G+S+ + G ++TG + S S + PTH
Sbjct: 2158 GQSGH--------------GQST-----QTGSRTTGRQRSSHSESSDSEVHSEASPTH 2196
Score = 35.0 bits (79), Expect = 0.63
Identities = 88/456 (19%), Positives = 157/456 (34%), Gaps = 34/456 (7%)
Query: 158 GAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTD 217
G+ S Y++S SG S + H + GS E + ++ T D
Sbjct: 1952 GSGHSEYSDSEGPSGVSHTHSG-----HTHGQA---GSHYPESGSSVHERHGTTHGQTAD 2003
Query: 218 NNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTEN 277
+ G +ST GS T+ G+ + S S +E + GV + Q+ + E+
Sbjct: 2004 TTRHGHSGHGQSTQRGSRTT--GRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGES 2061
Query: 278 NNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVS 337
+ + +R G G + S Q G+ G + +S SS
Sbjct: 2062 GSSV--------HERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEV 2113
Query: 338 TVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFG 397
G + A SG + IH G +G T ++ + G
Sbjct: 2114 HSGVSHTHSGHTYGQARSQHGESG---SAIHGRQGTIHGQTGD---TTRHGQSGHGQSTQ 2167
Query: 398 MGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNGKEREDSW 457
G T R + S+S+ D + S S G + + S SG++G+ +
Sbjct: 2168 TGSRTTGRQRSSHSESS-DSEVHSEAS-PTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQ 2225
Query: 458 KGASVQKSTGSKNDSWDNNNRSTG--GSWNFGPQDSNDNKWGEGNKM--TSGVSQGEWKQ 513
G + + + S +R+TG GS + DS + WG G + + +Q
Sbjct: 2226 TGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQ 2285
Query: 514 PTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQS 573
P + ++ G + G G+ G+ + S S+ + G S
Sbjct: 2286 PGSTVHGRLETTHGQTGDTTRHG----HSGYGQSTQTGSRSSRASHFQSHSSERQRHGSS 2341
Query: 574 TGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLS 609
H + ++ G Y P+ +++ + LS
Sbjct: 2342 QVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLS 2377
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 74.7 bits (182), Expect = 7e-13
Identities = 195/920 (21%), Positives = 325/920 (35%), Gaps = 156/920 (16%)
Query: 152 PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211
P S+ GG S + S SG S + + P + D S + P AS+ T +
Sbjct: 1493 PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTP-----QGRSDASHGQSGPRSASRQTRNE 1547
Query: 212 SENTTDNNSASNPGSEKSTLPGSTT-SNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270
++ + + + E ST GS+ S G+G S +S + + D + S S
Sbjct: 1548 EQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDS 1607
Query: 271 ---SNSTTENNNGLGNWRNVSG--------QDRIGPG--------SGFSNFNPNSNPSAW 311
S S + N+ G ++ G +DR G SG + +S A
Sbjct: 1608 ERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQA- 1666
Query: 312 PALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTD 371
+ ++ S G SA ST T R Q S + N SG +Q +++
Sbjct: 1667 ASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSG---SQASDSE 1723
Query: 372 G-PKNGNTNSLNL---SSPNPMENKGMPFGMGLGNTSRS--------TDAPSQSTGDRKT 419
G + +T S++ + P+ ++ G + RS T S+S R
Sbjct: 1724 GHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTG 1783
Query: 420 GSVGSWGAAR------------GPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTG 467
S G +R G DT+ G S G G E S + S
Sbjct: 1784 PSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHH 1843
Query: 468 SKNDSWDNNNRSTG--GSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEW 525
S S + ++ S G GS + Q N+ + G+G++ + + S ++G+
Sbjct: 1844 SHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQG 1903
Query: 526 --SGP----NQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNH- 578
SGP NQ +S + D+Q GH + + A S+ S G + GS+H
Sbjct: 1904 QSSGPRTSRNQGSSVSQDSDSQ-GHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHE 1962
Query: 579 -KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIE 637
+AG S +S R+S R ++ GQ +
Sbjct: 1963 DRAGHGHSADSSRQS---------------------GTRHTESSSRGQAASSHE------ 1995
Query: 638 EVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGG 697
+ +S G + G S + SG G AS+ +D + G
Sbjct: 1996 -----QARSSAG-----------ERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRG- 2038
Query: 698 WNDYKNNNSSNWGGGRPDEKTPSSWNENPS--KDQGWGGGRQPNQGWSSGKNG-WGEEVD 754
Y + +S+ G D T S + + Q + G SSG++G + +V
Sbjct: 2039 ---YSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVS 2095
Query: 755 QTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPN 814
+ S S P +G +G + + AS+ G + + P + GRQ +
Sbjct: 2096 THEQSESTHGQSAPSTGGRQGSHYD---QAQDSSRHSASQEGQDTIRGHPGPSRGGRQGS 2152
Query: 815 SWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPK--DEEP 872
HQ+Q + SG G R S SG + A+ K D+E
Sbjct: 2153 -----HQEQSV---------DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQ 2198
Query: 873 SGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPA---PREPNLPTPM 929
SG + S S S + S+W D + ++ L + GP PR ++
Sbjct: 2199 SG--DGSRHSGSHHHE----ASSWADSSRHS-----LVGQGQSSGPRTSRPRGSSVSQDS 2247
Query: 930 TSKSASDSKSMQDGWGE-------SDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHN- 981
S+ S+ + G + G+RHP E+ G ++ S + +H+
Sbjct: 2248 DSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHA 2307
Query: 982 -SASWGQGGKKQMKCSLKGG 1000
++S GQ + G
Sbjct: 2308 ENSSGGQAASSHEQARSSAG 2327
Score = 62.4 bits (150), Expect = 4e-09
Identities = 173/925 (18%), Positives = 308/925 (33%), Gaps = 117/925 (12%)
Query: 120 GGAGPPPCTAPGANPNNAQVTGALLQSESGTA-----PDSTLGGAAASNYANSTWGSGAS 174
G GP G+ AQ + S+ G P S+ GG ++ +S SG S
Sbjct: 2753 GWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS 2812
Query: 175 SNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGS 234
++ + H + D S + AS+ T + ++ + + + E ST
Sbjct: 2813 GSHHS-----HTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADI 2867
Query: 235 TTSNKGKGSQCQSASSGNECNLGVWK-SDPKAKSVQS---SNSTTENNNGLGNWRNVSGQ 290
+ ++ Q + + V + SD + S S S S + N++G S Q
Sbjct: 2868 SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHG-------SAQ 2920
Query: 291 DRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350
+++ GS +P S+ + G + Q S+ GQ + +
Sbjct: 2921 EQLRDGSR----HPRSHQED-----RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2971
Query: 351 ENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAP 410
+AG ++ A G +G +S S + +G N S D+
Sbjct: 2972 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH----RGYSGSQASDNEGHSEDSD 3027
Query: 411 SQSTGDRKTGSVGSWG-----AARGPSGTDTVSGQSNSGNNGNNGKEREDS---WKGASV 462
+QS G GS +ARG SG SG S S + E+ +S W G S
Sbjct: 3028 TQSVSAH--GQAGSHQQSHQESARGRSGE--TSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
Query: 463 QKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKI 522
+ GS+++ +++R + + QD+ G
Sbjct: 3084 RGRQGSRHEQAQDSSRHSASQYG---QDTIRGHPGSSR---------------------- 3118
Query: 523 GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGS 582
G G + +S + + H +QG + A S +GS ++T + ++G
Sbjct: 3119 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA-----SRGQSGSRSASRTTRNEEQSGD 3173
Query: 583 SDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRP 642
S H+ R TH D Q + +++ R S D+ E+ R
Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRR--SRRQGSSVSQDSDSEGHSEDSERW 3231
Query: 643 EGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYK 702
G + + G S Q+++ P ++ ++G G + + ++ + +
Sbjct: 3232 SGSASRNHRG--SVQEQSRHGSRH---PRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQ 3286
Query: 703 NNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNW- 761
+S P E+ S ++ + G R WG Q +S
Sbjct: 3287 AASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH 3346
Query: 762 -ESSASKPVSGWGEGGQN-----EIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNS 815
E S ++ VSG G+ G + E +GG + + ++ + + GR S
Sbjct: 3347 SEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTS 3406
Query: 816 WNKQ---HQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEP 872
++ H +Q E + G P S G Q + +
Sbjct: 3407 TGRRQGSHHEQARDSSRHSASQEGQDTIRGHP-----------GSSRRGRQGSHYEQSVD 3455
Query: 873 SGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSK 932
S S + D + S + + N + Q G R S
Sbjct: 3456 RSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRN----DEQSGDGSRHSWSHHHEAST 3511
Query: 933 SASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQ 992
A S+ Q G G+S GP T + V + SQG S +S W +
Sbjct: 3512 QADSSRHSQSGQGQSAGPRT-------SRNQGSSVSQDSDSQG--HSEDSERWSGSASRN 3562
Query: 993 MKCSLKGGNNDSWMNPLAKQFSNMG 1017
+ S + + D +P + G
Sbjct: 3563 HRGSAQEQSRDGSRHPTSHHEDRAG 3587
Score = 62.0 bits (149), Expect = 5e-09
Identities = 165/868 (19%), Positives = 303/868 (34%), Gaps = 150/868 (17%)
Query: 210 SSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQ 269
S E + D + S +T G + +++G+ S +SAS K+ K +S
Sbjct: 2152 SHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ-SGSRSASR---------KTYDKEQSGD 2201
Query: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329
S + +++ +W + S +G G + P ++ ++ Q+ S + +++
Sbjct: 2202 GSRHSGSHHHEASSWADSSRHSLVGQGQ---SSGPRTSRPRGSSVSQDSDSEGHSEDSER 2258
Query: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389
+ SA + G S ++QS+ G + H+ D +G++ + S
Sbjct: 2259 RSGSASRNHHG--SAQEQSR----------DGSRHPRSHHEDRAGHGHSAESSRQS---- 2302
Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNN 449
G + S+ + S+ ++ S G + D+ S S G+ +
Sbjct: 2303 ---------GTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS-SRHSGIGHGQAS 2352
Query: 450 GKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGP------QDSNDNKWGEGNKMT 503
R+ +G+S +++ S+ S D++ +S GP + + G +
Sbjct: 2353 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 2412
Query: 504 SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQK------------GHPLPENQG 551
S + Q + + S + G +G Q + A D+ + GHP + G
Sbjct: 2413 SFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGG 2472
Query: 552 -------------------NAQAPCWGRSSSS---TGSEVGGQSTGSNHKAGSSDSHNSG 589
++ GRS +S +GS + T ++ ++G H+
Sbjct: 2473 RQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGS 2532
Query: 590 RRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKG 649
R + D Q +++ PR N G +Q D+ E+ R G + +
Sbjct: 2533 RHHEASSRADSSGHSQVGQGQSE-GPRTSRNWGSSFSQ-DSDSQGHSEDSERWSGSASRN 2590
Query: 650 TEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNT----GGWNDYKNNN 705
G SA Q ++ P + ++G G + S+ ++T GG +
Sbjct: 2591 HHG--SAQEQLRDG---SRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQ 2645
Query: 706 SSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSA 765
+ + G R S + S+ G G G+ + SG G+ + E S
Sbjct: 2646 ARSSAGERHGSHHQQS--ADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 2703
Query: 766 SKPVSGWGEGG----QNEIGTWGNGGNAS------LASKGGWEDCKRSPAW---NETGRQ 812
++ VS G+ G ++ G G S L E + S W + GRQ
Sbjct: 2704 TQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQ 2763
Query: 813 PNSW-----NKQHQQQQPPQQPPPPQP----------------EASGSWGGPPPPPPGNV 851
+ + +H Q Q P ++SG G
Sbjct: 2764 GSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQG 2823
Query: 852 RPSNSSWSSGPQPA--TPKDEEPSG----------WEEPSPQSISRKMDIDDGTSAWGDP 899
R S SG + A T ++EE SG E + ISR G S G
Sbjct: 2824 RSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSE-GSR 2882
Query: 900 NSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHP-S 958
S + D +S+G E + + S + ++D G+RHP S
Sbjct: 2883 RSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRD----------GSRHPRS 2932
Query: 959 WEEEEDGGVWNTTGSQGSASSHNSASWG 986
+E+ G + S+ S + H S G
Sbjct: 2933 HQEDRAGHGHSADSSRQSGTRHTQTSSG 2960
Score = 59.7 bits (143), Expect = 2e-08
Identities = 156/826 (18%), Positives = 264/826 (31%), Gaps = 97/826 (11%)
Query: 206 KDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKA 265
+D+E SE+ S + GS GS GS+ + + + G A
Sbjct: 301 RDSEGHSED-----SERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHG-----HSA 350
Query: 266 KSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGAL 325
S + S + + G + Q R PG + + S S+ + G +
Sbjct: 351 DSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVS 410
Query: 326 ETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSG------REQAQIHNTDGPKNGNTN 379
+ + SS G + + + EN+ V SG R+Q+ +T G ++G +
Sbjct: 411 DRGHRGSS------GSQASDSEGHSENSDTQSV-SGHGKAGLRQQSHQESTRG-RSGERS 462
Query: 380 SLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSG 439
+ SS + P G T ST S ++ S + G DT+ G
Sbjct: 463 GRSGSSLYQVSTHEQP-DSAHGRTGTSTGGRQGSHHEQARDSSRH---SASQEGQDTIRG 518
Query: 440 QSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTG--GSWNFGPQDSNDNKWG 497
S G G E S + S S S ++ S G GS + Q N+ + G
Sbjct: 519 HPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSG 578
Query: 498 EGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPC 557
+G + + Q S ++G+ G NQG++ +
Sbjct: 579 DGTRHSGSRHHEASSQADSSRHSQVGQ--------------GQSSGPRTSRNQGSSVSQD 624
Query: 558 WGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRV 617
S SE S NH + + G R R H D + S R
Sbjct: 625 SDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRH 684
Query: 618 LSNTGWGQTQIKQDTVWDI--------EEVPRPEGKSDKGTEGWESAATQTKNSGGWGDA 669
N+ GQ + ++ + GT G A++ ++SG G +
Sbjct: 685 TQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGT-GHGQASSAVRDSGHRGSS 743
Query: 670 PSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS-----SWNE 724
SQ+ + G E + T+ G + + S+ G ++ S S ++
Sbjct: 744 GSQATDSE-GHSE-DSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHK 801
Query: 725 NPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWG 784
GW G P+ G G + NS +S + G G + G G
Sbjct: 802 QSESSHGWTG---PSTGVRQGSH----HEQARDNSRHSASQDGQDTIRGHPGSSRRGRQG 854
Query: 785 N------------GGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPP 832
+ G + S + G D R + + + + + Q + +
Sbjct: 855 SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTT--RNEEQSRDGSRHSGSR 912
Query: 833 QPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDG 892
EAS G + S S + +D + G E S + G
Sbjct: 913 HHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG 972
Query: 893 TSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMT-SKSASDSKSMQDGWGESDGPV 951
++ + + + D+ G A TP + S + S + S G
Sbjct: 973 SAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGER 1032
Query: 952 TGARHPSWEEEE---------------DGGVWNTTGSQGSASSHNS 982
G+RH + D G W ++GSQ S S +S
Sbjct: 1033 HGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHS 1078
Score = 57.0 bits (136), Expect = 2e-07
Identities = 179/891 (20%), Positives = 297/891 (33%), Gaps = 128/891 (14%)
Query: 152 PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211
P S+ GG S+Y SG S ++ + H + D S AS+ T +
Sbjct: 2466 PGSSSGGRQGSHYEQLVDRSGHSGSHHS-----HTTSQGRSDASHGHSGSRSASRQTRND 2520
Query: 212 SENTTDN-NSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270
++ + +S S S S S G+G +S N + SD + S S
Sbjct: 2521 EQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS 2580
Query: 271 ---SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
S S + N++G S Q+++ GS +P S+ + G
Sbjct: 2581 ERWSGSASRNHHG-------SAQEQLRDGSR----HPRSHQED-----RAGHGHSADSSR 2624
Query: 328 DNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPN 387
+ Q S+ GQ + + +AG ++ A G +G +S S +
Sbjct: 2625 QSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH 2684
Query: 388 PMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWG-----AARGPSG--------- 433
+G N S D+ +QS G GS +ARG SG
Sbjct: 2685 ----RGYSGSQASDNEGHSEDSDTQSVSAH--GQAGSHQQSHQESARGRSGETSGHSGSF 2738
Query: 434 ---------TDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSW 484
+++ G + G G E + + S ++ + S GG
Sbjct: 2739 LYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQ 2798
Query: 485 NFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH 544
+ + S D+ G+ + SQG G + + N+ S G+ + H
Sbjct: 2799 GYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRH 2858
Query: 545 PLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604
++ + A S + G G + + + S DS + G H +
Sbjct: 2859 ----HEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEG-------HSEDSERW 2907
Query: 605 QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664
SR ++ G Q Q++ + G +S T+ S
Sbjct: 2908 SGSASR--------NHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSS 2959
Query: 665 GWGDAPSQSNQMKSGWGELSAS--TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSW 722
G G A S Q +S GE S + D G + +++ G R + +S
Sbjct: 2960 G-GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 3018
Query: 723 NENPSKD--------QGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSA---SKPVSG 771
NE S+D G G Q + S + GE + + ++ S S+ G
Sbjct: 3019 NEGHSEDSDTQSVSAHGQAGSHQQSH-QESARGRSGETSGHSGSFLYQVSTHEQSESSHG 3077
Query: 772 W----GEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQ 827
W G Q + AS+ G + + P + GRQ ++ +H
Sbjct: 3078 WTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQ--GYHHEH------- 3128
Query: 828 QPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPA--TPKDEEPSGWEEPSPQSISR 885
++SG G R S SG + A T ++EE SG + S S+SR
Sbjct: 3129 -----SVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSG--DSSRHSVSR 3181
Query: 886 KMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWG 945
+ S D + ++ S+G R S S S+ + G
Sbjct: 3182 HHE----ASTHADISRHS----QAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSG 3233
Query: 946 ESD----GPVT-----GARHP-SWEEEEDGGVWNTTGSQGSASSHNSASWG 986
+ G V G+RHP S E+ G + S+ S + H S G
Sbjct: 3234 SASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSG 3284
Score = 53.1 bits (126), Expect = 2e-06
Identities = 182/888 (20%), Positives = 306/888 (34%), Gaps = 119/888 (13%)
Query: 152 PDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESS 211
P S GG S++ S SG S ++ + H + D S + AS+ T
Sbjct: 1169 PGSRRGGRQGSHHEQSVDRSGHSGSHHS-----HTTSQGRSDASHGQSGSRSASRQTRKD 1223
Query: 212 SENTTDN-NSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQS 270
++ + +S S S S S G+ S +S ++ + SD + S S
Sbjct: 1224 KQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDS 1283
Query: 271 ---SNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
S S + N++G S +++ GS F+ S + + + + G T
Sbjct: 1284 ERLSGSASRNHHG-------SSREQSRDGSRHPGFHQEDRASHGHSA--DSSRQSGTHHT 1334
Query: 328 DNSNSSAQVSTVGQT---------SREQQS--KMENAGVNFVVSGREQAQIHNTDGPKNG 376
++S+ VS+ Q SR QQS ++G+ G QA D G
Sbjct: 1335 ESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI-----GHRQASSAVRDSGHRG 1389
Query: 377 N-----TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGP 431
+ TNS S + ++ G S A QS G+ S
Sbjct: 1390 SSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQS-GESSGRSRSFLYQVSSH 1448
Query: 432 SGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDS 491
+++ GQ+ G G E + + S ++ + S GG + S
Sbjct: 1449 EQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQS 1508
Query: 492 NDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQG 551
D G + QG G + N+ S G+ + H P
Sbjct: 1509 VDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPST-- 1566
Query: 552 NAQAPCWGRSSSSTGSEVG-GQSTGS--NHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLL 608
R+ SS S+VG G+S GS + + GSS S + D + +
Sbjct: 1567 --------RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDR----------DSEGHSEDSE 1608
Query: 609 SRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGD 668
R++ R + Q++ +E G S E + T+ + G
Sbjct: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHS---AESSRQSGTRHAETSSGGQ 1665
Query: 669 APSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWG--GGRPDEKTPSSWNENP 726
A S Q +S GE S + ++ + +SS G G R + +S +E
Sbjct: 1666 AASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH 1725
Query: 727 SKD--------QGWGGGRQPN-----QGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWG 773
S++ G G Q + +G S ++G +++ +S ++ +G
Sbjct: 1726 SEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPS 1785
Query: 774 EGG-QNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPP 832
GG Q + AS+ G + + P + GRQ + H +Q
Sbjct: 1786 TGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGS-----HYEQ--------- 1831
Query: 833 QPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPAT--PKDEEPSG----------WEEPSP 880
++SG G R S SG + + ++E+ SG E S
Sbjct: 1832 SVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSR 1891
Query: 881 QSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSM 940
SR + G S+ G S N + D +SQG E S SAS +
Sbjct: 1892 ADSSRHSQVGQGQSS-GPRTSRNQGSSVSQDSDSQGHSEDSE------RWSGSAS-RNHL 1943
Query: 941 QDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQG 988
W +S G+RHP E+ G ++ S + + ++ S +G
Sbjct: 1944 GSAWEQSR---DGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRG 1988
Score = 50.8 bits (120), Expect = 1e-05
Identities = 145/797 (18%), Positives = 261/797 (32%), Gaps = 141/797 (17%)
Query: 204 ASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDP 263
++ + S T N+S+ S S G Q QSA S G
Sbjct: 673 SADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTG------ 726
Query: 264 KAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKG 323
Q+S++ ++ + R SG + T +G
Sbjct: 727 ---HGQASSAVRDSGH-----RGSSG--------------------------SQATDSEG 752
Query: 324 ALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNL 383
E ++ S VS GQ QQS E+A R + +S
Sbjct: 753 HSEDSDTQS---VSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGW 809
Query: 384 SSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNS 443
+ P+ +G N+ S Q T GS + RG G+ S
Sbjct: 810 TGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGS-----SRRGRQGSHHEQSVDRS 864
Query: 444 GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMT 503
G++G++ + + + +GS++ S N + S D G++
Sbjct: 865 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE----------EQSRDGSRHSGSRHH 914
Query: 504 SGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSS 563
S + + + + + + + SS + +GH + + A R S+
Sbjct: 915 EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSA 974
Query: 564 STGSEVGGQSTGSNH--KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNT 621
S G + S+H +AG S +S R+S P H + + Q S
Sbjct: 975 QEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTP-HAETSSGGQAASSHEQARSSPGERH 1033
Query: 622 GWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWG 681
G Q + +PR A++ ++SG WG + SQ++
Sbjct: 1034 GSRHQQSADSS--RHSGIPR------------RQASSAVRDSGHWGSSGSQAS------- 1072
Query: 682 ELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQG 741
+ +E D ++ G G P +++ ++ ++D W GGR
Sbjct: 1073 DSEGHSEESDTQSVSG-----------HGQDGPHQQS----HQESARD--WSGGR----- 1110
Query: 742 WSSGKNG-WGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDC 800
SG++G + +V + S ++ +G +G +E + AS+ G +
Sbjct: 1111 --SGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHE---QARDSSRHSASQEGQDTI 1165
Query: 801 KRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSS 860
+ P GRQ H+Q + SG G R S S
Sbjct: 1166 RAHPGSRRGGRQ----GSHHEQ----------SVDRSGHSGSHHSHTTSQGRSDASHGQS 1211
Query: 861 GPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAP 920
G + A+ + + + S S SR + ++W D + ++ + + S G
Sbjct: 1212 GSRSASRQTRKDKQSGDGSRHSGSRHHE----AASWADSSRHS----QVGQEQSSGSRTS 1263
Query: 921 REPNLPTPMTSKS---------ASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTT 971
R S S S S S + G+RHP + +E+ ++
Sbjct: 1264 RHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSA 1323
Query: 972 GSQGSASSHNSASWGQG 988
S + +H++ S G
Sbjct: 1324 DSSRQSGTHHTESSSHG 1340
Score = 50.4 bits (119), Expect = 1e-05
Identities = 147/715 (20%), Positives = 236/715 (33%), Gaps = 98/715 (13%)
Query: 319 TSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG-------VNFVVSGREQAQIHNTD 371
+SR+ ++S Q ++ + +R + +G +GR QA +D
Sbjct: 352 SSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSD 411
Query: 372 GPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGP 431
G++ S S EN G G + +ST R G G++
Sbjct: 412 RGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ 471
Query: 432 SGT----DTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFG 487
T D+ G++ + G G E + + S ++ + S GG
Sbjct: 472 VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 531
Query: 488 PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547
+ S + G+ + SQG G + N+ S G + H
Sbjct: 532 HEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRH--- 588
Query: 548 ENQGNAQAPCWGRSSSSTGSEVG-GQSTG--SNHKAGSSDSHNSGRRSYRPTHPDCQAVL 604
++ ++QA SS S+VG GQS+G ++ GSS S +S + H +
Sbjct: 589 -HEASSQA------DSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQG----HSEDSERW 637
Query: 605 QTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSG 664
SR ++ G Q Q + + G +S T+NS
Sbjct: 638 SGSASR--------NHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSS 689
Query: 665 GWGDAPSQSNQMKSGWGELSAS---TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSS 721
G A S Q +S GE S + D G + +++ G R + ++
Sbjct: 690 S-GQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQAT 748
Query: 722 WNENPSKD------QGWG-GGRQPNQGWSSGKNGWGE----------EVDQTKNSNWESS 764
+E S+D G G G S ++ GE +V K S
Sbjct: 749 DSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHG 808
Query: 765 ASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQ 824
+ P +G +G +E + AS+ G + + P + GRQ H+Q
Sbjct: 809 WTGPSTGVRQGSHHE---QARDNSRHSASQDGQDTIRGHPGSSRRGRQ----GSHHEQ-- 859
Query: 825 PPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPA--TPKDEEPS--------- 873
+ SG G R S SG + A T ++EE S
Sbjct: 860 --------SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGS 911
Query: 874 -GWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSK 932
E S ISR G S G S + D +S+G S+
Sbjct: 912 RHHEASSHADISRHSQAGQGQSE-GSRTSRRQGSSVSQDSDSEGHSE----------DSE 960
Query: 933 SASDSKSMQDGWGESDGPVTGARHP-SWEEEEDGGVWNTTGSQGSASSHNSASWG 986
S S S + G+RHP S E+ G + S+ S + H S G
Sbjct: 961 RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSG 1015
Score = 48.1 bits (113), Expect = 7e-05
Identities = 153/793 (19%), Positives = 272/793 (34%), Gaps = 119/793 (15%)
Query: 196 DMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPG---STTSNKGKGSQCQSASSGN 252
D E W AS++ S + + + S +P S G S ++ G++ SSG
Sbjct: 3227 DSERWSGSASRNHRGSVQEQSRHGSR-HPRSHHEDRAGHGHSADRSRQSGTRHAETSSGG 3285
Query: 253 ECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWP 312
+ A S + + S+ +G + ++ G G ++ + + W
Sbjct: 3286 QA----------ASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQAS-SAVRDSRHWG 3334
Query: 313 ALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDG 372
+ + + +G E ++ S VS GQ QQS E+A + G
Sbjct: 3335 SSGSQASDSEGHSEESDTQS---VSGHGQAGPHQQSHQESA--------------RDRSG 3377
Query: 373 PKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSR------------STDAPSQSTGDRKTG 420
++G + S L + E G +T R S + SQ D G
Sbjct: 3378 GRSGRSGSF-LYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRG 3436
Query: 421 SVGSWGAARGPSGTDTVSGQSNSGNNGNN-----GKEREDSWKGASVQKSTGSKNDSWDN 475
GS + RG G+ SG++G++ + R D+ +G S +S + + +
Sbjct: 3437 HPGS--SRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQ 3494
Query: 476 NNRSTGGSWNFGPQ------DSNDNKWGEG--------NKMTSGVSQGEWKQPTGSDELK 521
+ + SW+ + S ++ G+G S VSQ Q D +
Sbjct: 3495 SGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSER 3554
Query: 522 IGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSSSTG-----SEVGGQS 573
WSG N A + + HP ++ A SS +G + GGQ+
Sbjct: 3555 ---WSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQA 3611
Query: 574 TGSNHKAGSSDSHNSGRRSYRPT---------HPDCQAVLQTLLSRTDLDPRVLSNTGWG 624
S+ +A SS G + H + ++ R + + G
Sbjct: 3612 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHS 3671
Query: 625 QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELS 684
+ Q + P + + T G +A ++ SG + S Q +S G
Sbjct: 3672 EDSDTQSVSAHGQAGPHQQSHQE-STRG--RSAGRSGRSGSFLYQVSTHEQSESAHGRAG 3728
Query: 685 ASTEWKDPKNTGGWNDYKNNNSSNWG----GGRPDEK---TPSSWNENPSKDQGWGGGR- 736
ST + D +++S G G P + S++E G G
Sbjct: 3729 PSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHH 3788
Query: 737 -----QPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASL 791
Q S G++G +T+N S+ SG +E T + S
Sbjct: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRH-SG---SRHHEASTQADSSRHSQ 3844
Query: 792 ASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGP--PPPPPG 849
+ +G +RS RQ +S ++ + P+ AS + G G
Sbjct: 3845 SGQGESAGSRRS------RRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDG 3898
Query: 850 NVRPSNS--SWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDP---NSYNY 904
+ P +S +S Q + + + + E S+S+ G + G P +SY+Y
Sbjct: 3899 SRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHY 3958
Query: 905 KNVNLWDKNSQGG 917
++ + Q G
Sbjct: 3959 QSEGTERQKGQSG 3971
Score = 45.8 bits (107), Expect = 4e-04
Identities = 187/958 (19%), Positives = 321/958 (33%), Gaps = 123/958 (12%)
Query: 210 SSSENTTDNNSASNPGSEKSTLPGSTTSNKGK-GSQCQSASSGNECNLGVWKSDPKAKSV 268
S E + D + S +T G + +++G+ GS+ S ++ NE ++
Sbjct: 855 SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHH 914
Query: 269 Q-SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
+ SS++ ++ G ++ + GS S + + S E + R +
Sbjct: 915 EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHS-------EDSERWSGSAS 967
Query: 328 DNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNT-NSLNLSSP 386
N SAQ + + + + AG Q+ + + G +S +
Sbjct: 968 RNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARS 1027
Query: 387 NPMENKGMPFGMGLGNTSRSTDAPSQ--STGDRKTGSVGSWGAARGPS-------GTDTV 437
+P E G ++SR + P + S+ R +G GS G+ S T +V
Sbjct: 1028 SPGERHGSRHQQS-ADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSV 1086
Query: 438 SGQSNSGNNGNNGKEREDSWKGAS--------VQKSTGSKNDSWDNNNR-STG---GSWN 485
SG G + + +E W G Q ST +++S R STG GS +
Sbjct: 1087 SGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHH 1146
Query: 486 FGPQDSNDNKWGEGNKMT-----------------------SGVSQGEWKQPTGSDELKI 522
+DS+ + + + T SG S T
Sbjct: 1147 EQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA 1206
Query: 523 GEWSGPNQPNSSTGAWDNQKGH-PLPENQGNAQAPCWGRSS--SSTGSEVGGQSTGSNHK 579
++ S D Q G + +A W SS S G E S S H+
Sbjct: 1207 SHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQ 1266
Query: 580 AGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDL-DPRVLSNTGWGQTQIKQDTVWDIEE 638
S + R H D L SR R S G Q+
Sbjct: 1267 GSSVSQDSDSER-----HSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQED--RASH 1319
Query: 639 VPRPEGKSDKGTEGWESAA--------TQTKNSGG--WGDAPSQS--NQMKSGWGELSAS 686
+ GT ES++ Q ++S G G QS + SG G AS
Sbjct: 1320 GHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQAS 1379
Query: 687 TEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGK 746
+ +D + G N+ + D ++ S+ + Q + G SSG+
Sbjct: 1380 SAVRDSGHRGSSGSQVTNSEGH--SEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437
Query: 747 N-GWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPA 805
+ + +V + S + P +G +G ++E + AS+ G + + P
Sbjct: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHE---QARNSSRHSASQDGQDTIRGHPG 1494
Query: 806 WNETGRQPNSWNKQ------HQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWS 859
+ GRQ S+++Q H P + +AS GP R ++
Sbjct: 1495 SSRGGRQ-GSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGP--------RSASRQTR 1545
Query: 860 SGPQPATPKDEEPSGWEEPSPQS-ISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGP 918
+ Q S EPS ++ SR + G SA G S + D++S+G
Sbjct: 1546 NEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESA-GSKTSRRQGSSVSQDRDSEGHS 1604
Query: 919 APREPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHP-SWEEEEDGGVWNTTGSQGSA 977
S+ S+S S + G+R+P S +E+ + S+ S
Sbjct: 1605 E----------DSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSG 1654
Query: 978 SSH-NSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGS 1036
+ H ++S GQ Q + G + + S T+ + D SV
Sbjct: 1655 TRHAETSSGGQAASSQEQARSSPGERHGSRHQQSAD-------SSTDSGTGRRQDSSVVG 1707
Query: 1037 LSDKKFDVDKRAMNL---GDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLF 1091
S + +A + + +D G P+ + + G E+ G G F
Sbjct: 1708 DSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSF 1765
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 66.2 bits (160), Expect = 3e-10
Identities = 70/343 (20%), Positives = 128/343 (37%), Gaps = 15/343 (4%)
Query: 146 SESGTAPDSTLGGAAASNYANSTWGSGAS--SNNGTSPNPIHIWDKVIVDGSDMEEWPCI 203
SES T ++ G + A+N +ST SGAS +N+ +S D S
Sbjct: 108 SESST---TSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAST 164
Query: 204 AS---KDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWK 260
A+ T SS +T N+ +S S ST S +S G+ + S + G
Sbjct: 165 ATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGT 224
Query: 261 SDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTS 320
+ S SS ++T N + S G G+ ++ + ++ A A E ++
Sbjct: 225 ATNSESSTTSSGASTATN-------SESSTPSSGAGTATNSESSTTSSGAGTATNSESST 277
Query: 321 RKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNS 380
+ T ++ S+ S+ T+ +S ++G N + N +++
Sbjct: 278 VSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESST 337
Query: 381 LNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQ 440
+ + ++ G + S + + S T S S ++ + T + S
Sbjct: 338 TSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESST 397
Query: 441 SNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGS 483
++SG + E GAS ++ S S N + GS
Sbjct: 398 TSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGS 440
Score = 58.9 bits (141), Expect = 4e-08
Identities = 83/471 (17%), Positives = 167/471 (35%), Gaps = 25/471 (5%)
Query: 141 GALLQSESGTAPDSTLGGAAASNYANSTWGSGASS--NNGTSPNPIHIWDKVIVDGSDME 198
G LL E+ T + T + ++N +S SGAS+ N+G+S + I S
Sbjct: 13 GLLLHLEAATNSNET---STSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTS 69
Query: 199 EWPCIASKD---TESSSENTTDNNSASN--------PGSEKSTLPGSTTSNKGKGSQCQS 247
I + T SS +T N+ S SE ST ++ S S
Sbjct: 70 NGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPS 129
Query: 248 ASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSN 307
+ + N + A + +S+S+T ++ + S G + ++ + +
Sbjct: 130 SGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVS 189
Query: 308 PSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQI 367
A A E ++ T ++ S S T+ +S ++G + +
Sbjct: 190 SRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPS 249
Query: 368 HNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGA 427
N +++ + + ++ G+ + S + S + T S S +
Sbjct: 250 SGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTS 309
Query: 428 ARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFG 487
+ + T++ S ++SG + E + GAS ++ S S + + GS
Sbjct: 310 SGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTS 369
Query: 488 PQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547
S E + ++SG S + S G + N +S+ + G
Sbjct: 370 SGTSTATN-SESSTVSSGASTATTSE---SSTTSSGASTATNSESSTVSS-----GASTA 420
Query: 548 ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHP 598
N ++ +++++GS V +G+ G + +S + P
Sbjct: 421 TNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKP 471
Score = 38.5 bits (88), Expect = 0.057
Identities = 34/141 (24%), Positives = 57/141 (40%), Gaps = 11/141 (7%)
Query: 140 TGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEE 199
+GA + S ++ S+ G + A+N +ST SGAS+ + + S
Sbjct: 310 SGANTATNSDSSTTSS-GASTATNSESSTTSSGASTATNSESSTT----------SSGAS 358
Query: 200 WPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVW 259
+ T SS +T N+ +S S ST S +S G+ + S + + G
Sbjct: 359 TATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGAS 418
Query: 260 KSDPKAKSVQSSNSTTENNNG 280
+ S SS + T N+G
Sbjct: 419 TATNSESSTTSSGANTATNSG 439
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 65.9 bits (159), Expect = 3e-10
Identities = 55/137 (40%), Positives = 73/137 (53%), Gaps = 22/137 (16%)
Query: 1097 QSRGLHTPV-----QPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQL 1151
Q+ GL +P +PL S+ A + PQ I+PQ +L+Q LSP L
Sbjct: 69 QTSGLKSPKSSDKQRPLQVPVSV-AMMTPQVITPQQMQQILQQ---QVLSPQQLQA---L 121
Query: 1152 SPQQIAMLSQLPQIPQF------QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLAR 1205
QQ A++ Q Q+ +F QL QLL QQQQQQQ Q Q++ Q +QQQ+QQ +
Sbjct: 122 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 181
Query: 1206 MVSALQQQQQQQQRQPG 1222
QQQQQQQQ+ PG
Sbjct: 182 Q----QQQQQQQQQHPG 194
Score = 31.2 bits (69), Expect = 9.1
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 1150 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1209
Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + +
Sbjct: 177 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 235
Query: 1210 LQQQ 1213
LQ+Q
Sbjct: 236 LQRQ 239
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 64.3 bits (155), Expect = 1e-09
Identities = 48/113 (42%), Positives = 62/113 (54%), Gaps = 16/113 (14%)
Query: 1116 AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF------Q 1169
A + PQ I+PQ +L+Q LSP L QQ A++ Q Q+ +F Q
Sbjct: 117 AMMTPQVITPQQMQQILQQ---QVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQ 170
Query: 1170 LACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 1222
L QLL QQQQQQQ Q Q++ Q +QQQ+QQ + QQQQQQQQ+ PG
Sbjct: 171 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPG 219
Score = 40.4 bits (93), Expect = 0.015
Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 19/123 (15%)
Query: 1108 LNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQ 1167
L S S Q P Q + P+ + G F V P +AM++ PQ
Sbjct: 73 LKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAV-----PVSVAMMTPQVITPQ 127
Query: 1168 F--QLACQLLLQQQQQQQLLQNQRKISQAVRQQQE--------QQLARMVSALQQQQQQQ 1217
Q+ Q +L QQ Q LLQ Q QAV QQ+ QQ + LQQQQQQQ
Sbjct: 128 QMQQILQQQVLSPQQLQALLQQQ----QAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ 183
Query: 1218 QRQ 1220
Q+Q
Sbjct: 184 QQQ 186
Score = 31.2 bits (69), Expect = 9.1
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 1150 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1209
Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + +
Sbjct: 202 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 260
Query: 1210 LQQQ 1213
LQ+Q
Sbjct: 261 LQRQ 264
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 63.5 bits (153), Expect = 2e-09
Identities = 69/230 (30%), Positives = 92/230 (40%), Gaps = 13/230 (5%)
Query: 1000 GNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMR 1059
G W + +Q L+SQ ED S D + V +A ++ ++
Sbjct: 5 GQETDWRSTAFRQ----KLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
Query: 1060 KDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPV----QPLNSSPSLR 1115
+ FR ++K + S P L G A + G+ P Q L SL
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPM---NALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLG 117
Query: 1116 AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLL 1175
A P +S Q P+S QL QQ+A L Q Q QFQ Q
Sbjct: 118 AMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVA-LQQQQQQQQFQQQQQAA 176
Query: 1176 LQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKH 1225
LQQQQQQQ Q Q + Q+ QQQ Q + + LQQQQQQQQ + H
Sbjct: 177 LQQQQQQQQ-QQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Score = 42.7 bits (99), Expect = 0.003
Identities = 82/310 (26%), Positives = 112/310 (36%), Gaps = 47/310 (15%)
Query: 1144 LFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQL 1203
L + Q QQ L ++ Q+ Q Q QQQQQQQ LQ Q I Q QQ +
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 1204 ARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGS 1263
++ AL QQ QQ M H+ H P+P + N + P QT+ P+
Sbjct: 283 SQ---ALPQQLQQ------MHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ-PLVSQAQ 332
Query: 1264 GFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGA--IVAPG----- 1316
G M Y K R P V Q+ + A +VAPG
Sbjct: 333 AL-PGQMLYTQPPLKFV----RAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMIT 387
Query: 1317 --KTRGG-------SPYNQFDIIPGDTLGGHTGP---AGDSWLPAKSPPT--NKIGSKSS 1362
+GG P IP ++ P S LP S P+ ++ + S
Sbjct: 388 EALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQS 447
Query: 1363 NASWP-PEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNS 1421
P P QPG P N + S P +P S L + P + + +
Sbjct: 448 MPPPPQPSPQPGQP-SSQPNSNVSSGPAPSPSSFLPSPSPQP---------SQSPVTART 497
Query: 1422 SLNTSLPSPG 1431
N S+PSPG
Sbjct: 498 PQNFSVPSPG 507
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 10/66 (15%)
Query: 821 QQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSP 880
Q Q P PPPPQP P P P + NS+ SSGP P +P PS +PS
Sbjct: 441 QVQTPQSMPPPPQP-------SPQPGQPSS--QPNSNVSSGPAP-SPSSFLPSPSPQPSQ 490
Query: 881 QSISRK 886
++ +
Sbjct: 491 SPVTAR 496
Score = 32.7 bits (73), Expect = 3.1
Identities = 52/199 (26%), Positives = 77/199 (38%), Gaps = 54/199 (27%)
Query: 853 PSNSSWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDK 912
P SS S G Q TP+ P +PSPQ G P+S NV+
Sbjct: 431 PMLSSPSPGQQVQTPQSMPPP--PQPSPQP--------------GQPSSQPNSNVS---- 470
Query: 913 NSQGGPAPREPNL---PTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWN 969
GPAP + P+P S+S +++ Q+ S GP+ +PS V +
Sbjct: 471 ---SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPS-------SVMS 520
Query: 970 TTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSK 1029
GS Q ++Q LK ++ PL + ++++ + N K
Sbjct: 521 PAGS------------SQAEEQQYLDKLK--QLSKYIEPLRR------MINKIDKNEDRK 560
Query: 1030 MDLS-VGSLSDKKFDVDKR 1047
DLS + SL D D KR
Sbjct: 561 KDLSKMKSLLDILTDPSKR 579
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 63.5 bits (153), Expect = 2e-09
Identities = 69/230 (30%), Positives = 92/230 (40%), Gaps = 13/230 (5%)
Query: 1000 GNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMR 1059
G W + +Q L+SQ ED S D + V +A ++ ++
Sbjct: 5 GQETDWRSTAFRQ----KLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA 60
Query: 1060 KDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPV----QPLNSSPSLR 1115
+ FR ++K + S P L G A + G+ P Q L SL
Sbjct: 61 RLIIHFRDIHNKKSQASVSDPM---NALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLG 117
Query: 1116 AQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLL 1175
A P +S Q P+S QL QQ+A L Q Q QFQ Q
Sbjct: 118 AMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVA-LQQQQQQQQFQQQQQAA 176
Query: 1176 LQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKH 1225
LQQQQQQQ Q Q + Q+ QQQ Q + + LQQQQQQQQ + H
Sbjct: 177 LQQQQQQQQ-QQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Score = 41.6 bits (96), Expect = 0.007
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 1144 LFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQL 1203
L + Q QQ L ++ Q+ Q Q QQQQQQQ LQ Q I Q QQ +
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 1204 ARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTK 1255
++ AL QQ QQ M H+ H P+P + N + P QT+
Sbjct: 283 SQ---ALPQQLQQ------MHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ 325
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 10/66 (15%)
Query: 821 QQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSP 880
Q Q P PPPPQP P P P + NS+ SSGP P +P PS +PS
Sbjct: 401 QVQTPQSMPPPPQP-------SPQPGQPSS--QPNSNVSSGPAP-SPSSFLPSPSPQPSQ 450
Query: 881 QSISRK 886
++ +
Sbjct: 451 SPVTAR 456
Score = 36.6 bits (83), Expect = 0.22
Identities = 60/235 (25%), Positives = 88/235 (37%), Gaps = 60/235 (25%)
Query: 823 QQPPQQPPPPQPEAS------GSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWE 876
QQPP QP Q + + P + P SS S G Q TP+ P
Sbjct: 355 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPP--P 412
Query: 877 EPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNL---PTPMTSKS 933
+PSPQ G P+S NV+ GPAP + P+P S+S
Sbjct: 413 QPSPQP--------------GQPSSQPNSNVS-------SGPAPSPSSFLPSPSPQPSQS 451
Query: 934 ASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQM 993
+++ Q+ S GP+ +PS V + GS Q ++Q
Sbjct: 452 PVTARTPQNFSVPSPGPLNTPVNPS-------SVMSPAGS------------SQAEEQQY 492
Query: 994 KCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLS-VGSLSDKKFDVDKR 1047
LK ++ PL + ++++ + N K DLS + SL D D KR
Sbjct: 493 LDKLK--QLSKYIEPLRR------MINKIDKNEDRKKDLSKMKSLLDILTDPSKR 539
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 62.8 bits (151), Expect = 3e-09
Identities = 47/109 (43%), Positives = 60/109 (55%), Gaps = 16/109 (14%)
Query: 1120 PQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQF------QLACQ 1173
PQ I+PQ +L+Q LSP L QQ A++ Q Q+ +F QL Q
Sbjct: 4 PQVITPQQMQQILQQ---QVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 57
Query: 1174 LLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPG 1222
LL QQQQQQQ Q Q++ Q +QQQ+QQ + QQQQQQQQ+ PG
Sbjct: 58 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPG 102
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/79 (40%), Positives = 37/79 (46%), Gaps = 9/79 (11%)
Query: 1150 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1209
Q QQ Q Q Q Q Q QQQQQQQ Q Q QA QQQ+QQ + ++A
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120
Query: 1210 ---------LQQQQQQQQR 1219
LQ QQ QQQ+
Sbjct: 121 QQLVFQQQLLQMQQLQQQQ 139
Score = 31.2 bits (69), Expect = 9.1
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 1150 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSA 1209
Q QQ Q Q P Q A + QQQQQQQL Q Q + Q Q+ Q + + +
Sbjct: 85 QQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 143
Query: 1210 LQQQ 1213
LQ+Q
Sbjct: 144 LQRQ 147
>gi|11761629 fibrinogen, alpha polypeptide isoform alpha
preproprotein [Homo sapiens]
Length = 644
Score = 62.8 bits (151), Expect = 3e-09
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 32/173 (18%)
Query: 401 GNTSRSTDAPSQSTGDRKTGSVGSWGA-ARGPSGTDTVSGQSNSGNNGNNGKEREDSWK- 458
G+TS T + ++S R S GSW + + GP T G N G++G G +WK
Sbjct: 273 GSTSYGTGSETESP--RNPSSAGSWNSGSSGPGST----GNRNPGSSGTGGTA---TWKP 323
Query: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518
G+S STGS W++ + TG + N P S G W P S+
Sbjct: 324 GSSGPGSTGS----WNSGSSGTGSTGNQNPGSPRPG------------STGTWN-PGSSE 366
Query: 519 ELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQA----PCWGRSSSSTGS 567
G W+ + + STG W ++ G P++ G+ A P WG +G+
Sbjct: 367 RGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419
Score = 53.1 bits (126), Expect = 2e-06
Identities = 50/152 (32%), Positives = 64/152 (42%), Gaps = 23/152 (15%)
Query: 458 KGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGS 517
+G S TGS+ +S N S+ GSWN G S G N +SG +P S
Sbjct: 271 RGGSTSYGTGSETES--PRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSS 326
Query: 518 DELKIGEWSGPNQPNSSTGAWDNQK-GHPLPENQGNAQAPCWGRSSSSTGS--------E 568
G W N +S TG+ NQ G P P + G W SS GS
Sbjct: 327 GPGSTGSW---NSGSSGTGSTGNQNPGSPRPGSTGT-----WNPGSSERGSAGHWTSESS 378
Query: 569 VGGQSTGSNH-KAGSSDSHNSGRRSYRPTHPD 599
V G STG H ++GS + G + RP +PD
Sbjct: 379 VSG-STGQWHSESGSFRPDSPGSGNARPNNPD 409
Score = 47.4 bits (111), Expect = 1e-04
Identities = 52/206 (25%), Positives = 73/206 (35%), Gaps = 40/206 (19%)
Query: 667 GDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDE--KTPSS--- 721
G+ SQ ++ W L+ + + G N+ S+++G G E + PSS
Sbjct: 235 GNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGS 294
Query: 722 WNENPSKDQGWGGGRQPNQG-------WSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE 774
WN S G G R P W G +G G S+ S G
Sbjct: 295 WNSG-SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPR 353
Query: 775 GGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQP 834
G GTW N G++ S G W S TG+ W+ +
Sbjct: 354 PGST--GTW-NPGSSERGSAGHWTS--ESSVSGSTGQ----WHSE--------------- 389
Query: 835 EASGSWGGPPPPPPGNVRPSNSSWSS 860
SGS+ P P GN RP+N W +
Sbjct: 390 --SGSFR-PDSPGSGNARPNNPDWGT 412
Score = 37.0 bits (84), Expect = 0.17
Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 13/141 (9%)
Query: 644 GKSDKGTEGWESAATQTKNSGGWGDA---PSQSNQMKSGWGELSASTEWKD----PKNTG 696
G + GT + ++G W P + G + WK P +TG
Sbjct: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332
Query: 697 GWNDYKNNNSS--NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNG-WGEEV 753
WN + S N G P + +W NP + G ++ SG G W E
Sbjct: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTW--NPGSSERGSAGHWTSESSVSGSTGQWHSES 390
Query: 754 DQTKNSNWESSASKPVS-GWG 773
+ + S ++P + WG
Sbjct: 391 GSFRPDSPGSGNARPNNPDWG 411
Score = 36.6 bits (83), Expect = 0.22
Identities = 47/206 (22%), Positives = 76/206 (36%), Gaps = 41/206 (19%)
Query: 345 EQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTS 404
+ + ++E G N + G G + T S S NP G ++
Sbjct: 256 QMRMELERPGGNEITRG----------GSTSYGTGSETESPRNPSSAGSWNSGSSGPGST 305
Query: 405 RSTDAPSQSTGDRKT--------GSVGSWGAARGPSGTDTVS---------GQSNSGNNG 447
+ + S TG T GS GSW + G SGT + G + + N G
Sbjct: 306 GNRNPGSSGTGGTATWKPGSSGPGSTGSWNS--GSSGTGSTGNQNPGSPRPGSTGTWNPG 363
Query: 448 NNGKEREDSWKG-ASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506
++ + W +SV STG + + + GS N P N+ WG +++ V
Sbjct: 364 SSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARP---NNPDWGTFEEVSGNV 420
Query: 507 SQGEWKQ--------PTGSDELKIGE 524
S G ++ G EL+ G+
Sbjct: 421 SPGTRREYHTEKLVTSKGDKELRTGK 446
Score = 35.8 bits (81), Expect = 0.37
Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 9/123 (7%)
Query: 1417 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMW 1476
TGS + + S G+W +S T + + +TW P G T N
Sbjct: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNS-- 336
Query: 1477 KNHISSRNTTPLPRPPPGLTNPKPSSPWS--STAPRSVRGWGTQDSRLASASTW-SDGGS 1533
S T PG P + W+ S+ S W ++ S S W S+ GS
Sbjct: 337 ----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392
Query: 1534 VRP 1536
RP
Sbjct: 393 FRP 395
Score = 34.7 bits (78), Expect = 0.82
Identities = 46/176 (26%), Positives = 65/176 (36%), Gaps = 37/176 (21%)
Query: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329
S + N + G+W + S GPGS N NP S+ + A + G+S G+ + N
Sbjct: 281 SETESPRNPSSAGSWNSGSS----GPGST-GNRNPGSSGTGGTATWKPGSSGPGSTGSWN 335
Query: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389
S SS ST Q N P+ G+T + N P
Sbjct: 336 SGSSGTGSTGNQ---------------------------NPGSPRPGSTGTWN---PGSS 365
Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
E + S ST +G + S GS G AR P+ D + + SGN
Sbjct: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS-GNAR-PNNPDWGTFEEVSGN 419
Score = 33.9 bits (76), Expect = 1.4
Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 38/215 (17%)
Query: 89 REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA--GPPPCTAPGANPNNAQVTGALLQS 146
++VPP ++ D + + P + + GG G T NP++A G+
Sbjct: 242 QKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSA---GSWNSG 298
Query: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206
SG ++ +TW G+S T S
Sbjct: 299 SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST------------------------GSW 334
Query: 207 DTESSSENTTDNNS--ASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
++ SS +T N + + PGS + PGS+ +S+ SG + G W S+
Sbjct: 335 NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG---STGQWHSESG 391
Query: 265 AKSVQS--SNSTTENNNGLGNWRNVSGQDRIGPGS 297
+ S S + NN G + VSG + PG+
Sbjct: 392 SFRPDSPGSGNARPNNPDWGTFEEVSG--NVSPGT 424
>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
preproprotein [Homo sapiens]
Length = 866
Score = 62.8 bits (151), Expect = 3e-09
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 32/173 (18%)
Query: 401 GNTSRSTDAPSQSTGDRKTGSVGSWGA-ARGPSGTDTVSGQSNSGNNGNNGKEREDSWK- 458
G+TS T + ++S R S GSW + + GP T G N G++G G +WK
Sbjct: 273 GSTSYGTGSETESP--RNPSSAGSWNSGSSGPGST----GNRNPGSSGTGGTA---TWKP 323
Query: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518
G+S STGS W++ + TG + N P S G W P S+
Sbjct: 324 GSSGPGSTGS----WNSGSSGTGSTGNQNPGSPRPG------------STGTWN-PGSSE 366
Query: 519 ELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQA----PCWGRSSSSTGS 567
G W+ + + STG W ++ G P++ G+ A P WG +G+
Sbjct: 367 RGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419
Score = 53.1 bits (126), Expect = 2e-06
Identities = 50/152 (32%), Positives = 64/152 (42%), Gaps = 23/152 (15%)
Query: 458 KGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGS 517
+G S TGS+ +S N S+ GSWN G S G N +SG +P S
Sbjct: 271 RGGSTSYGTGSETES--PRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSS 326
Query: 518 DELKIGEWSGPNQPNSSTGAWDNQK-GHPLPENQGNAQAPCWGRSSSSTGS--------E 568
G W N +S TG+ NQ G P P + G W SS GS
Sbjct: 327 GPGSTGSW---NSGSSGTGSTGNQNPGSPRPGSTGT-----WNPGSSERGSAGHWTSESS 378
Query: 569 VGGQSTGSNH-KAGSSDSHNSGRRSYRPTHPD 599
V G STG H ++GS + G + RP +PD
Sbjct: 379 VSG-STGQWHSESGSFRPDSPGSGNARPNNPD 409
Score = 47.4 bits (111), Expect = 1e-04
Identities = 52/206 (25%), Positives = 73/206 (35%), Gaps = 40/206 (19%)
Query: 667 GDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDE--KTPSS--- 721
G+ SQ ++ W L+ + + G N+ S+++G G E + PSS
Sbjct: 235 GNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGS 294
Query: 722 WNENPSKDQGWGGGRQPNQG-------WSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE 774
WN S G G R P W G +G G S+ S G
Sbjct: 295 WNSG-SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPR 353
Query: 775 GGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQP 834
G GTW N G++ S G W S TG+ W+ +
Sbjct: 354 PGST--GTW-NPGSSERGSAGHWTS--ESSVSGSTGQ----WHSE--------------- 389
Query: 835 EASGSWGGPPPPPPGNVRPSNSSWSS 860
SGS+ P P GN RP+N W +
Sbjct: 390 --SGSFR-PDSPGSGNARPNNPDWGT 412
Score = 37.0 bits (84), Expect = 0.17
Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 13/141 (9%)
Query: 644 GKSDKGTEGWESAATQTKNSGGWGDA---PSQSNQMKSGWGELSASTEWKD----PKNTG 696
G + GT + ++G W P + G + WK P +TG
Sbjct: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332
Query: 697 GWNDYKNNNSS--NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNG-WGEEV 753
WN + S N G P + +W NP + G ++ SG G W E
Sbjct: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTW--NPGSSERGSAGHWTSESSVSGSTGQWHSES 390
Query: 754 DQTKNSNWESSASKPVS-GWG 773
+ + S ++P + WG
Sbjct: 391 GSFRPDSPGSGNARPNNPDWG 411
Score = 36.6 bits (83), Expect = 0.22
Identities = 47/206 (22%), Positives = 76/206 (36%), Gaps = 41/206 (19%)
Query: 345 EQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTS 404
+ + ++E G N + G G + T S S NP G ++
Sbjct: 256 QMRMELERPGGNEITRG----------GSTSYGTGSETESPRNPSSAGSWNSGSSGPGST 305
Query: 405 RSTDAPSQSTGDRKT--------GSVGSWGAARGPSGTDTVS---------GQSNSGNNG 447
+ + S TG T GS GSW + G SGT + G + + N G
Sbjct: 306 GNRNPGSSGTGGTATWKPGSSGPGSTGSWNS--GSSGTGSTGNQNPGSPRPGSTGTWNPG 363
Query: 448 NNGKEREDSWKG-ASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506
++ + W +SV STG + + + GS N P N+ WG +++ V
Sbjct: 364 SSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARP---NNPDWGTFEEVSGNV 420
Query: 507 SQGEWKQ--------PTGSDELKIGE 524
S G ++ G EL+ G+
Sbjct: 421 SPGTRREYHTEKLVTSKGDKELRTGK 446
Score = 35.8 bits (81), Expect = 0.37
Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 9/123 (7%)
Query: 1417 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMW 1476
TGS + + S G+W +S T + + +TW P G T N
Sbjct: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNS-- 336
Query: 1477 KNHISSRNTTPLPRPPPGLTNPKPSSPWS--STAPRSVRGWGTQDSRLASASTW-SDGGS 1533
S T PG P + W+ S+ S W ++ S S W S+ GS
Sbjct: 337 ----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392
Query: 1534 VRP 1536
RP
Sbjct: 393 FRP 395
Score = 34.7 bits (78), Expect = 0.82
Identities = 46/176 (26%), Positives = 65/176 (36%), Gaps = 37/176 (21%)
Query: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329
S + N + G+W + S GPGS N NP S+ + A + G+S G+ + N
Sbjct: 281 SETESPRNPSSAGSWNSGSS----GPGST-GNRNPGSSGTGGTATWKPGSSGPGSTGSWN 335
Query: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389
S SS ST Q N P+ G+T + N P
Sbjct: 336 SGSSGTGSTGNQ---------------------------NPGSPRPGSTGTWN---PGSS 365
Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
E + S ST +G + S GS G AR P+ D + + SGN
Sbjct: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS-GNAR-PNNPDWGTFEEVSGN 419
Score = 33.9 bits (76), Expect = 1.4
Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 38/215 (17%)
Query: 89 REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA--GPPPCTAPGANPNNAQVTGALLQS 146
++VPP ++ D + + P + + GG G T NP++A G+
Sbjct: 242 QKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSA---GSWNSG 298
Query: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206
SG ++ +TW G+S T S
Sbjct: 299 SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST------------------------GSW 334
Query: 207 DTESSSENTTDNNS--ASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
++ SS +T N + + PGS + PGS+ +S+ SG + G W S+
Sbjct: 335 NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG---STGQWHSESG 391
Query: 265 AKSVQS--SNSTTENNNGLGNWRNVSGQDRIGPGS 297
+ S S + NN G + VSG + PG+
Sbjct: 392 SFRPDSPGSGNARPNNPDWGTFEEVSG--NVSPGT 424
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 62.0 bits (149), Expect = 5e-09
Identities = 99/434 (22%), Positives = 138/434 (31%), Gaps = 105/434 (24%)
Query: 619 SNTGWGQ-----TQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQS 673
SN+GW I D+ W P G S GW S S W PS S
Sbjct: 32 SNSGWASPSASGASIPSDSGW---ASPSASGASTPSNSGWASF------SASWASIPSDS 82
Query: 674 NQMKSGWGELSASTEWKDPKNTGGWNDYKNNNS---SNWGGGRPD---EKTPSSWNENPS 727
GW SAS W + GW + + S+ G P PS++ +PS
Sbjct: 83 -----GWASPSAS--WASTPSDSGWASPSASGASIPSDSGWASPSVSGASIPSAFWASPS 135
Query: 728 KDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGG 787
G + GW+S W + +S W S P + W + + +G
Sbjct: 136 AS---GASTPSDSGWASPSASW---ASTSSDSGWAS----PSASWTSPSASCASSSASG- 184
Query: 788 NASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPP 847
AS S GW S W S SW P
Sbjct: 185 -ASTPSDSGW--ASPSVFW---------------------------VSPSTSWASSPSDF 214
Query: 848 PGNVRPSNSSWSS------GPQPATPKDEEPSGWEEPSPQ--SISRKMDIDDGTSAWGDP 899
PS+S W+S P + SGW PS S S S W
Sbjct: 215 GWASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWAS- 273
Query: 900 NSYNYKNVN----------LWDKNSQG-GPAPREPNLPTPMTSKSASDSKSMQDGWGESD 948
+S ++ ++ W +S AP + +P S++++ S S GW
Sbjct: 274 SSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVS---GWASFS 330
Query: 949 GPVTGARHPS---WEEEEDGGVWNTTG------SQGSASSHNSASWGQGGKKQMKCSLKG 999
+GA PS W GV T+ S AS+ + + W S G
Sbjct: 331 --ASGASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPSASG 388
Query: 1000 GNNDS---WMNPLA 1010
+ S W +P A
Sbjct: 389 ASTPSDSGWASPSA 402
Score = 60.1 bits (144), Expect = 2e-08
Identities = 90/411 (21%), Positives = 136/411 (33%), Gaps = 56/411 (13%)
Query: 431 PSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTG-----------SKNDSWDNNNRS 479
PSG+ S ++ + +N S GAS+ +G N W S
Sbjct: 15 PSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGW----AS 70
Query: 480 TGGSWNFGPQDSNDNKWGEGN-KMTSGVSQGEWKQP--TGSDELKIGEWSGPNQPNSS-- 534
SW P DS W + S S W P +G+ W+ P+ +S
Sbjct: 71 FSASWASIPSDSG---WASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSGASIP 127
Query: 535 TGAW--DNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRS 592
+ W + G P + G A S+SS ++ ++ A + S SG +
Sbjct: 128 SAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGAST 187
Query: 593 YRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEV----PRPEGKSDK 648
P+ + +S + S+ GW T D+ W P G S
Sbjct: 188 --PSDSGWASPSVFWVSPSTSWASSPSDFGWAST--PSDSGWASSSASCISPSASGASTS 243
Query: 649 GTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGW---NDYKNNN 705
GW S S W + S G S+S W + GW + ++
Sbjct: 244 SDSGWASP------SASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASS 297
Query: 706 SSNWGGGRPD--EKTPSSWNENPSKDQGW------GGGRQPNQGWSSGKNGWGEEVDQTK 757
S++W D +PS + GW G + GW+S V T
Sbjct: 298 SASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHS---ASGVSTTS 354
Query: 758 NSNWES-SASKPVSGWGEGGQNEIGTWG--NGGNASLASKGGWEDCKRSPA 805
+S W S SAS + G + +W + AS S GW S A
Sbjct: 355 DSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGA 405
Score = 44.7 bits (104), Expect = 8e-04
Identities = 94/469 (20%), Positives = 172/469 (36%), Gaps = 71/469 (15%)
Query: 121 GAGPPPCTAPGAN-PNNA-----QVTGALLQSESGTAPDSTLGGAAASNYA----NSTWG 170
G+G +A GA+ P+N+ +GA + S+SG A S G + SN +++W
Sbjct: 17 GSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWA 76
Query: 171 SGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKST 230
S S + SP+ W D W + + S + +D+ AS P ++
Sbjct: 77 SIPSDSGWASPSA--SWASTPSDSG----W----ASPSASGASIPSDSGWAS-PSVSGAS 125
Query: 231 LPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQ 290
+P + ++ + SG W S + + SS+S + + +W + S
Sbjct: 126 IPSAFWASPSASGASTPSDSG-------WASPSASWASTSSDSGWASPS--ASWTSPSAS 176
Query: 291 DRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKM 350
SG S P+ + A P++ S A + S G S S
Sbjct: 177 CASSSASGAS--TPSDSGWASPSVFWVSPSTSWA---------SSPSDFGWASTPSDSGW 225
Query: 351 ENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAP 410
++ + + A + G + + + ++ S+ + G ++S S D+
Sbjct: 226 ASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSS----DSGWASSSASWDSI 281
Query: 411 SQSTG-----DRKTGSVGSWGAARGPSGTD--TVSGQSNSGNNGNNGKEREDSWKGASVQ 463
+ +G S SW +A SG+ +VS S +G W S
Sbjct: 282 TSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSG---------WASFSAS 332
Query: 464 KSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKM-TSGVSQGEWKQPTGSDELKI 522
++ + W +++ S G ++D+ W + S S W P+ S
Sbjct: 333 GASAPSDSGWTSHSAS-------GVSTTSDSGWASPSASGASTSSDSGWASPSAS--WAS 383
Query: 523 GEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGG 571
SG + P+ S A + G +P C+ + ++ TG V G
Sbjct: 384 PSASGASTPSDSGWASPSASGASMPSAPSLCPGSCFPQLTARTGFTVVG 432
Score = 37.4 bits (85), Expect = 0.13
Identities = 65/303 (21%), Positives = 98/303 (32%), Gaps = 43/303 (14%)
Query: 436 TVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNK 495
+ SG S ++G SW S S + SW + + S S G +D+
Sbjct: 135 SASGASTPSDSG--WASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSG 192
Query: 496 WGE--------GNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLP 547
W S S W T SD + P++S + + G P
Sbjct: 193 WASPSVFWVSPSTSWASSPSDFGWAS-TPSDSGWASSSASCISPSASGASTSSDSGWASP 251
Query: 548 ENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSH--------NSGRRSYRPTHPD 599
+A S +ST S+ G S+ ++ + +SDS S S+ D
Sbjct: 252 ----SASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSD 307
Query: 600 CQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQ 659
+ ++ SR LS +GW + SD G ++
Sbjct: 308 SGSSSPSV-SRAS----TLSVSGWASFSASGASA-----------PSDSGWTSHSASGVS 351
Query: 660 TKNSGGWGD--APSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEK 717
T + GW A S SGW SAS W P +G + +S G
Sbjct: 352 TTSDSGWASPSASGASTSSDSGWASPSAS--WASPSASGASTPSDSGWASPSASGASMPS 409
Query: 718 TPS 720
PS
Sbjct: 410 APS 412
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 58.9 bits (141), Expect = 4e-08
Identities = 47/120 (39%), Positives = 61/120 (50%), Gaps = 22/120 (18%)
Query: 1149 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQR---------KISQAVRQQQ 1199
P+LS Q + L QL Q Q QL Q LQQQQQQQL Q Q+ + Q ++QQQ
Sbjct: 3887 PKLSAQPMGSLQQLQQ--QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQ 3944
Query: 1200 EQQLARMVSALQQQQQQQQ---------RQPGMKHSPSHPVGPKPHLDNMVPNALNVGLP 1250
+QQL + LQQQQQQQQ +Q G+ + + P+ V AL G+P
Sbjct: 3945 QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV--ALGPGMP 4002
Score = 54.7 bits (130), Expect = 8e-07
Identities = 46/131 (35%), Positives = 61/131 (46%), Gaps = 15/131 (11%)
Query: 1150 QLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLA----- 1204
QL QQ+ Q Q+ Q Q Q LQQQQQQ Q Q++ Q +QQQ+QQ+
Sbjct: 3925 QLQQQQLQQQQQQQQLQQQQ---QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981
Query: 1205 -RMVSALQQQQQQQQRQPGMKHSP----SHP--VGPKPHLDNMVPNALNVGLPDLQTKGP 1257
++S QQQQQQ PGM P S P +GP L N ++ + T+GP
Sbjct: 3982 RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGP 4041
Query: 1258 IPGYGSGFSSG 1268
G + G
Sbjct: 4042 STHQGGPLAIG 4052
Score = 44.3 bits (103), Expect = 0.001
Identities = 54/179 (30%), Positives = 77/179 (43%), Gaps = 26/179 (14%)
Query: 1084 KGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPG 1143
+G G G G+ P QP P L + Q + P+ G PG
Sbjct: 3645 QGPPGGQAGGLRLTPGGMALPGQP--GGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPG 3702
Query: 1144 LFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQL 1203
L+ + + S+L Q Q QL QQQ+ QL Q K+ Q +QQQ+QQ
Sbjct: 3703 ------NLALRSLGPDSRLLQERQLQL-------QQQRMQLAQ---KLQQQQQQQQQQQH 3746
Query: 1204 ARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYG 1262
A+QQQQQQ PG++ + +GPKP ++P + + GL +Q P P G
Sbjct: 3747 LLGQVAIQQQQQQ---GPGVQ--TNQALGPKP--QGLMPPSSHQGLL-VQQLSPQPPQG 3797
Score = 41.6 bits (96), Expect = 0.007
Identities = 50/180 (27%), Positives = 72/180 (40%), Gaps = 36/180 (20%)
Query: 1149 PQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVS 1208
P+ +++ ++++ Q QL Q+ QQ++ L+ R +QQQ+QQ
Sbjct: 3557 PEADAEKLKLVTEQQSKIQKQLD-QVRKQQKEHTNLMAEYRN-----KQQQQQQ------ 3604
Query: 1209 ALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSG--FS 1266
QQQQQQQQ + SPS P L +P L G +GP G G +
Sbjct: 3605 --QQQQQQQQHSAVLALSPSQ----SPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLT 3658
Query: 1267 SGGMDY-GMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYN 1325
GGM G GG T ++A Q+ H GA G + G P N
Sbjct: 3659 PGGMALPGQPGGPFLNT---------------ALAQQQQQQHSGGAGSLAGPSGGFFPGN 3703
Score = 40.4 bits (93), Expect = 0.015
Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 11/86 (12%)
Query: 1148 GPQ--LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLA- 1204
GPQ L P Q+A+L Q Q L Q +Q L+ R +S QQ Q L
Sbjct: 3797 GPQGMLGPAQVAVLQQ-------QHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMG 3849
Query: 1205 -RMVSALQQQQQQQQRQPGMKHSPSH 1229
R+V+A QQQQQQQ +Q G SH
Sbjct: 3850 HRLVTAQQQQQQQQHQQQGSMAGLSH 3875
Score = 40.0 bits (92), Expect = 0.020
Identities = 95/379 (25%), Positives = 140/379 (36%), Gaps = 41/379 (10%)
Query: 1085 GGSHGLFGN--STAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSP 1142
GGSHG G+ S+ S H QP S + + PQ ML++ + P
Sbjct: 4113 GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQ--QPMLERPMQNNTGP 4170
Query: 1143 GLFNVGPQL-SPQQIAMLSQLPQIPQFQLACQLLL-----------QQQQQQQLLQNQRK 1190
GP L S Q + + +P + Q + Q +L QQQQQ Q L QR+
Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230
Query: 1191 I--SQAVRQQQE-QQLARMVSALQQQ---QQQQQRQPGMKHSPSHPVGPKPHLDN----- 1239
+ SQAVRQ Q+ S LQ Q Q PG + P +G P
Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290
Query: 1240 MVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGTESRF---KQWTSMMEGL 1296
P AL+ G P L P P S + TE++ T +G
Sbjct: 4291 APPGALSTG-PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG- 4348
Query: 1297 PSVATQEANMHKNGAIVAPGK-TRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTN 1355
P++ + A +A ++G P++ P D L P S +P N
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWD-----PPDNLAETQKPEQSSLVPGHLDQVN 4403
Query: 1356 -KIGSKSSNASWPPEFQPGVPWKGIQNIDPES--DPYVTPGSVLGGTATSPIVDTDHQLL 1412
++ ++S S E + G Q++ E+ +P PG+ P + H LL
Sbjct: 4404 GQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLL 4463
Query: 1413 RDNTTGSNSSLNTSLPSPG 1431
+ N L+T S G
Sbjct: 4464 QKLLRAKNVQLSTGRGSEG 4482
Score = 33.9 bits (76), Expect = 1.4
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 19/128 (14%)
Query: 1105 VQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQ 1164
VQ L+ P Q P + P A + +Q P + +GPQ P + +++Q
Sbjct: 3787 VQQLSPQPP---QGPQGMLGPAQVAVLQQQHPGA--------LGPQ-GPHRQVLMTQSRV 3834
Query: 1165 IPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMK 1224
+ QLA QQ Q L+ ++ +Q +QQQ+ Q ++ L QQ G
Sbjct: 3835 LSSPQLA-------QQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQP 3887
Query: 1225 HSPSHPVG 1232
+ P+G
Sbjct: 3888 KLSAQPMG 3895
Score = 32.3 bits (72), Expect = 4.1
Identities = 50/194 (25%), Positives = 76/194 (39%), Gaps = 14/194 (7%)
Query: 1075 TTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQ 1134
T +G + G G ST +S GL +P++P PS+ P P +S ++
Sbjct: 2581 TVATGNFHPSGSPLGPSSGSTGESYGL-SPLRP----PSVLPPPAPDGSLPYLSHGASQR 2635
Query: 1135 FPNSGL-SPGLFNVGPQLSPQQIAMLSQLP--QIPQFQLACQLLLQQQQQQQLLQNQRKI 1191
SG+ SP P ++LP Q P Q L++Q+Q+Q L+
Sbjct: 2636 ---SGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIR 2692
Query: 1192 SQAVRQ--QQEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGL 1249
Q R +QE++ A + +P G P ++L VGL
Sbjct: 2693 QQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSL-VGL 2751
Query: 1250 PDLQTKGPIPGYGS 1263
P + GPI G GS
Sbjct: 2752 PPSKLSGPILGPGS 2765
Score = 31.6 bits (70), Expect = 7.0
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 18/78 (23%)
Query: 823 QQPPQQPPPPQPEASGSWGGP--PPPPPGNVR-PSNSSWSSGP-------------QPAT 866
Q PP+ P PP ++G GP P PPP + + P S P P T
Sbjct: 4284 QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343
Query: 867 PKDEEPSGWEEPSPQSIS 884
PK + P+ EP P +S
Sbjct: 4344 PKPQGPT--LEPPPGRVS 4359
Score = 31.2 bits (69), Expect = 9.1
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 18/82 (21%)
Query: 1182 QQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQ-----PG------MKHSPSHP 1230
+ LL++++K Q++QQL+ + QQQQQQQQ+ PG + H S P
Sbjct: 3250 EDLLEHEKK-----ELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSP 3304
Query: 1231 --VGPKPHLDNMVPNALNVGLP 1250
G + L + A GLP
Sbjct: 3305 SLAGSQQQLSLGLAGARQPGLP 3326
>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
isoform d [Homo sapiens]
Length = 756
Score = 58.5 bits (140), Expect = 5e-08
Identities = 67/247 (27%), Positives = 90/247 (36%), Gaps = 52/247 (21%)
Query: 705 NSSNWGGGRPDEKTPSSWNENPSKDQGWGGG--RQPNQGWSSGKNGWGEEVDQTKNSNWE 762
N G P EK + + +G GGG R N+G G G +
Sbjct: 495 NEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNR--------- 545
Query: 763 SSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQ 822
G GG N G + G S+ W + R N S+N+ QQ
Sbjct: 546 -------GGGSGGGGNYRGGFNRSGGGGY-SQNRWGNNNRD---NNNSNNRGSYNRAPQQ 594
Query: 823 QQPPQQPPPPQPEASGSWGGPPPPP---PGNVRPSNSSW--SSGPQPATPKDEEPSGWEE 877
Q PPQQPPPPQP PPPPP P P S++ +S ++ P+
Sbjct: 595 QPPPQQPPPPQPPPQ----QPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSY 650
Query: 878 PSPQSISRKMDIDDGTSAWG---------DPNSYNYKNVNLWDKNSQGG--PAPREPNLP 926
PQ + + G + G P +YNY S GG PAP P P
Sbjct: 651 SPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNY--------GSYGGYNPAPYTP--P 700
Query: 927 TPMTSKS 933
P T+++
Sbjct: 701 PPPTAQT 707
Score = 38.9 bits (89), Expect = 0.044
Identities = 36/171 (21%), Positives = 62/171 (36%), Gaps = 16/171 (9%)
Query: 695 TGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754
+GG +Y+ + + GGG + ++ +N + + R P Q + +
Sbjct: 549 SGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPP 608
Query: 755 Q--TKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQ 812
Q ++ + + P + N G+ N +++S + P +N+ G
Sbjct: 609 QQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYS 668
Query: 813 PNSWNKQHQQQQPPQQPPPPQPEASGSWGG-------PPPPPPGNVRPSNS 856
PP PPPP GS+GG PPPPP P S
Sbjct: 669 QG-------YTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPS 712
Score = 34.7 bits (78), Expect = 0.82
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 429 RGPSGTDTVSGQSNSGNNGNNGKER---EDSWKGASVQKSTGSKNDSWDNNNRSTGGSWN 485
RGP G + Q+ G +G G R S G Q G+ N DNNN + GS+N
Sbjct: 532 RGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNR--DNNNSNNRGSYN 589
Query: 486 FGPQ 489
PQ
Sbjct: 590 RAPQ 593
>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
isoform a [Homo sapiens]
Length = 856
Score = 58.5 bits (140), Expect = 5e-08
Identities = 67/247 (27%), Positives = 90/247 (36%), Gaps = 52/247 (21%)
Query: 705 NSSNWGGGRPDEKTPSSWNENPSKDQGWGGG--RQPNQGWSSGKNGWGEEVDQTKNSNWE 762
N G P EK + + +G GGG R N+G G G +
Sbjct: 595 NEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNR--------- 645
Query: 763 SSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQ 822
G GG N G + G S+ W + R N S+N+ QQ
Sbjct: 646 -------GGGSGGGGNYRGGFNRSGGGGY-SQNRWGNNNRD---NNNSNNRGSYNRAPQQ 694
Query: 823 QQPPQQPPPPQPEASGSWGGPPPPP---PGNVRPSNSSW--SSGPQPATPKDEEPSGWEE 877
Q PPQQPPPPQP PPPPP P P S++ +S ++ P+
Sbjct: 695 QPPPQQPPPPQPPPQ----QPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSY 750
Query: 878 PSPQSISRKMDIDDGTSAWG---------DPNSYNYKNVNLWDKNSQGG--PAPREPNLP 926
PQ + + G + G P +YNY S GG PAP P P
Sbjct: 751 SPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNY--------GSYGGYNPAPYTP--P 800
Query: 927 TPMTSKS 933
P T+++
Sbjct: 801 PPPTAQT 807
Score = 38.9 bits (89), Expect = 0.044
Identities = 36/171 (21%), Positives = 62/171 (36%), Gaps = 16/171 (9%)
Query: 695 TGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVD 754
+GG +Y+ + + GGG + ++ +N + + R P Q + +
Sbjct: 649 SGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPP 708
Query: 755 Q--TKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQ 812
Q ++ + + P + N G+ N +++S + P +N+ G
Sbjct: 709 QQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYS 768
Query: 813 PNSWNKQHQQQQPPQQPPPPQPEASGSWGG-------PPPPPPGNVRPSNS 856
PP PPPP GS+GG PPPPP P S
Sbjct: 769 QG-------YTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPS 812
Score = 34.7 bits (78), Expect = 0.82
Identities = 23/64 (35%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Query: 429 RGPSGTDTVSGQSNSGNNGNNGKER---EDSWKGASVQKSTGSKNDSWDNNNRSTGGSWN 485
RGP G + Q+ G +G G R S G Q G+ N DNNN + GS+N
Sbjct: 632 RGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNR--DNNNSNNRGSYN 689
Query: 486 FGPQ 489
PQ
Sbjct: 690 RAPQ 693
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 57.8 bits (138), Expect = 9e-08
Identities = 50/196 (25%), Positives = 73/196 (37%), Gaps = 16/196 (8%)
Query: 654 ESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGR 713
E + + + N G G+ + +Q SG + P N G + + + G+
Sbjct: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYM--------PMNNWGSGNGRGSGGGQGSNGQ 510
Query: 714 PDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWG 773
S N+ + QG GG+ N G SG N + T + +P G G
Sbjct: 511 GSSSHSSGGNQCSGEGQGSRGGQGSN-GQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHG 569
Query: 774 EGGQNEIGTW-GNGGNASLASKGGWEDCKRSPAWNETGRQPNSWN------KQHQQQQPP 826
GG G G+GG + G K S E G+ + + QQQ PP
Sbjct: 570 SGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPP 629
Query: 827 QQPPPPQPEASGSWGG 842
PPPP P +G GG
Sbjct: 630 PPPPPPPPPPAGGTGG 645
Score = 41.2 bits (95), Expect = 0.009
Identities = 40/130 (30%), Positives = 47/130 (36%), Gaps = 26/130 (20%)
Query: 479 STGGSWNFG----PQDSND-----------NKWGEGNKMTSGVSQGEWKQPTGSDELKIG 523
S GS NFG PQ D N WG GN SG QG Q + S
Sbjct: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
Query: 524 EWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGS- 582
+ SG Q S G N +G G Q G+ ++ GGQ G H +G
Sbjct: 521 QCSGEGQ-GSRGGQGSNGQG------SGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGG 573
Query: 583 ---SDSHNSG 589
D H SG
Sbjct: 574 QGPGDGHGSG 583
Score = 39.7 bits (91), Expect = 0.026
Identities = 45/169 (26%), Positives = 61/169 (36%), Gaps = 19/169 (11%)
Query: 428 ARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTG-GSWNF 486
A P+ +S + + +GN G+E K + GS D NN +G G +
Sbjct: 447 AEAPNNGARLSSEVSGSGSGNFGEEGNPQGK----EDQEGSGGDYMPMNNWGSGNGRGSG 502
Query: 487 GPQDSN---DNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKG 543
G Q SN + G SG QG + GS+ G+ SG NQ S G
Sbjct: 503 GGQGSNGQGSSSHSSGGNQCSGEGQGS-RGGQGSN----GQGSGGNQ--CSRDGQGTAGG 555
Query: 544 HPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRS 592
H G Q P G S G +G +G SG+ S
Sbjct: 556 H----GSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGS 600
Score = 38.9 bits (89), Expect = 0.044
Identities = 103/474 (21%), Positives = 159/474 (33%), Gaps = 66/474 (13%)
Query: 388 PMENKGMPFGMGL--GNTSRSTDAPSQSTGDRK-----TGSVGSWGAARGPSGTDTVS-- 438
PM N G G G G S + S S+G + GS G G+ SG + S
Sbjct: 489 PMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRD 548
Query: 439 GQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGE 498
GQ +G +G+ G +R G+ + G + S +++GG G +D
Sbjct: 549 GQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGS--GGGKNSGGGKGSGSGKGSDGDGER 606
Query: 499 GNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGH---PLPENQGNAQA 555
G + G+ Q P P TG G ++G A
Sbjct: 607 GKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRG-ATK 665
Query: 556 PCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDP 615
C + +E+ + H+A + D Y P P V L+S +D P
Sbjct: 666 EC-KEAKEVKDAEIPEGAARGPHRARAFDEDEDD--PYVPMRP---GVATPLVSSSDYMP 719
Query: 616 RVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQ 675
N + + + D + A T D S+S+
Sbjct: 720 MAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDY 779
Query: 676 MKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNEN-------PSK 728
M G A K+P+N G + K + SS + P +P N+N P K
Sbjct: 780 MFMAPG---AGAIPKNPRNPQGGSSSK-SWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGK 835
Query: 729 DQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGN 788
G G ++ + W + D + E S SKP G+GG+
Sbjct: 836 FLGRGLDKEVSYNW--------DPKDAASKPSGEGSFSKP---------------GDGGS 872
Query: 789 ASLASKGGWEDCKRSPAWNETGRQPNSWN---KQHQQQQPPQQPPPPQPEASGS 839
S S P N+ ++PN + K ++ + PQ+P Q EA S
Sbjct: 873 PSKPS-------DHEPPKNK-AKRPNRLSFITKGYKIKPKPQKPTHEQREADSS 918
Score = 34.3 bits (77), Expect = 1.1
Identities = 48/236 (20%), Positives = 77/236 (32%), Gaps = 20/236 (8%)
Query: 643 EGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYK 702
+G + +G+ S Q G SN SG + S + + G
Sbjct: 505 QGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRP 564
Query: 703 NNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGR----QPNQGWSSGKNGWGEEVDQTKN 758
+ GG P + S +N +G G G+ +G S K + ++ Q+K
Sbjct: 565 GGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQ 624
Query: 759 SNWESSASKPVSGWGEGGQNEIGTWGNGGNASL---ASKGGWEDCKRSPAWNE------T 809
P GG G +GG L +G ++CK + +
Sbjct: 625 QQMPPPPPPPPPPPPAGGTG--GKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGA 682
Query: 810 GRQPN---SWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGP 862
R P+ ++++ P +P P S S P P NV S S P
Sbjct: 683 ARGPHRARAFDEDEDDPYVPMRPGVATPLVSSS--DYMPMAPQNVSASKKRHSRSP 736
Score = 33.5 bits (75), Expect = 1.8
Identities = 43/197 (21%), Positives = 69/197 (35%), Gaps = 30/197 (15%)
Query: 846 PPPGNVRPSNSSWSSGPQPATPKDEEPSG--WEEPSPQSISRKMDIDDGTSAWGDPNSYN 903
P P R + ++G + ++ SG EE +PQ +D + GD
Sbjct: 438 PSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGK------EDQEGSGGD----- 486
Query: 904 YKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSMQDGWGES---------------- 947
Y +N W + G + + +S S+ ++ +G G
Sbjct: 487 YMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCS 546
Query: 948 -DGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSWM 1006
DG T H S + GG + G QG H S G + S KG + D
Sbjct: 547 RDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGER 606
Query: 1007 NPLAKQFSNMGLLSQTE 1023
K+ S G L+Q++
Sbjct: 607 GKSLKKRSYFGKLTQSK 623
>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
sapiens]
Length = 1067
Score = 56.2 bits (134), Expect = 3e-07
Identities = 105/471 (22%), Positives = 167/471 (35%), Gaps = 108/471 (22%)
Query: 405 RSTDAPSQSTGDRKTGS---VGSWGAARGPSGT-DTVSGQSNSGNNGN------NGKERE 454
RSTDA S+ D SW G G + G+S N+G +G
Sbjct: 438 RSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGGHDN 497
Query: 455 DSWK-----GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQG 509
SW G +++ G S D N+ + G S+ N +G+ ++ G +
Sbjct: 498 SSWSDRYGVGGHYEENRGH---SLDANSGGRSPDTHSGGHSSSSNSYGQSHRY-GGEGRY 553
Query: 510 EWK---QPTGSDELKIGEWSGPNQPNSST------GAWDNQKGHPLPENQGNAQAPCW-- 558
E++ S +SG + +S + G ++ +G L N G +
Sbjct: 554 EYRGRSHDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSG 613
Query: 559 GRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVL 618
G SSS GG ++ S D+++ GR PD + D +
Sbjct: 614 GHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRS------PDAYS------GGHDSSGQSN 661
Query: 619 SNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWG----------- 667
G G+ + + + D G+S G +++Q+ GG G
Sbjct: 662 CYGGGGRYEEYRGRLLDANS----GGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLD 717
Query: 668 ---------------DAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGG 712
D+ SQS+ G L A++ + P G +D + + GGG
Sbjct: 718 ANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSHRYGGGG 777
Query: 713 RPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGW 772
R +E S + N GGR PN +S G N SS + P G
Sbjct: 778 RYEEYRGRSLDAN-------SGGRSPN-AYSGGHN--------------SSSRNDPCRG- 814
Query: 773 GEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGR--QPNSWNKQHQ 821
GG+ E N G++ A+ GG SP GR NS+++ H+
Sbjct: 815 --GGRYE----ENRGHSLDANSGG-----HSPNAYSGGRDSSSNSYDRSHR 854
Score = 51.6 bits (122), Expect = 7e-06
Identities = 105/462 (22%), Positives = 167/462 (36%), Gaps = 74/462 (16%)
Query: 405 RSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNN------GKEREDSWK 458
RS+ + S DR G G + RG S D SG NS +N G+ R + ++
Sbjct: 370 RSSSSNGYSRSDRY-GEEGCYEEYRGRS-PDAHSGGRNSSSNSYGQSHHYGGEGRYEEYR 427
Query: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518
G S + +G + S D ++R G DS+ W + G + E Q D
Sbjct: 428 GRSHEARSGGR--STDAHSRGRSDDAYSGGHDSSS--WSD---CCGGGGRYEEYQGRSLD 480
Query: 519 ELKIG----EWSGPNQPNSST------GAWDNQKGHPLPENQGNAQAPCWGRS--SSSTG 566
G +SG + +S + G ++ +GH L N G GRS + S G
Sbjct: 481 ANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSG-------GRSPDTHSGG 533
Query: 567 SEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQT 626
S G +H+ G + RS+ C A D + G G
Sbjct: 534 HSSSSNSYGQSHRYGGEGRYEYRGRSHDAHSGGCSA--DAYSGGHDSSSQSNRYGGGGCY 591
Query: 627 QIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSAS 686
+ + D G+S G +++ + GG G + L A+
Sbjct: 592 EEYRGRSLDANS----GGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGR------SLDAN 641
Query: 687 TEWKDPKNTGGWNDYKNNNSSNWGGGRPDE------------KTPSSW-----NENPSKD 729
+ + P G +D ++ GGGR +E ++P ++ + + S
Sbjct: 642 SGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNR 701
Query: 730 QGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEG-GQNEIG----TWG 784
G GG + +G S N G D + SS S G G N G +
Sbjct: 702 YGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYS 761
Query: 785 NGGNASLASK-----GGWEDCK-RSPAWNETGRQPNSWNKQH 820
G ++S S G +E+ + RS N GR PN+++ H
Sbjct: 762 GGHDSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAYSGGH 803
Score = 49.3 bits (116), Expect = 3e-05
Identities = 88/450 (19%), Positives = 160/450 (35%), Gaps = 60/450 (13%)
Query: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWG-------------AARGPSGTDT 436
EN+G G S T + S+ G +G A G D
Sbjct: 512 ENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRYEYRGRSHDAHSGGCSADA 571
Query: 437 VSG--QSNSGNNGNNGKEREDSWKGASVQKSTGSKN-DSWDNNNRSTGGSWNFGPQDSND 493
SG S+S +N G + ++G S+ ++G ++ +++ + S+ S +G +
Sbjct: 572 YSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYE 631
Query: 494 NKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNA 553
G SG + G D SG + G ++ +G L N G
Sbjct: 632 EYRGRSLDANSGGRSPD-AYSGGHDS------SGQSNCYGGGGRYEEYRGRLLDANSGGR 684
Query: 554 QAPCW--GRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRT 611
+ G SSS + GG ++ S D+++ GR PD + S++
Sbjct: 685 SPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGR------SPDTYSRGHDSSSQS 738
Query: 612 DLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPS 671
D + G G + ++ G+ G +++++ GG G
Sbjct: 739 D-------HYGGGGRSLDANS----------SGRLPDAYSGGHDSSSRSHRYGGGGRYEE 781
Query: 672 QSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPS--KD 729
+ L A++ + P G ++ + N GGGR +E S + N
Sbjct: 782 YRGR------SLDANSGGRSPNAYSGGHNSSSRNDPCRGGGRYEENRGHSLDANSGGHSP 835
Query: 730 QGWGGGR--QPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGG 787
+ GGR N S + G G ++ + + ++ S+ S G + + G
Sbjct: 836 NAYSGGRDSSSNSYDRSHRYGGGGHYEEYRGRSHDTH-SRGRSPDAHSGDHYTEAYSRGR 894
Query: 788 NASLASKGGWEDCKRSPAWNE-TGRQPNSW 816
++ S G + R + E GR PN++
Sbjct: 895 DSFSNSYGRSDHYGRGGCYEEYQGRSPNAY 924
Score = 42.4 bits (98), Expect = 0.004
Identities = 85/392 (21%), Positives = 143/392 (36%), Gaps = 32/392 (8%)
Query: 234 STTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSV-QSSNSTTENNNGLGNWRNVSGQDR 292
S+ SN+ G C G + P A S S+S + G G + G+
Sbjct: 579 SSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSL 638
Query: 293 IGPGSGFS-NFNPNSNPSAWPALVQEGTSR----KGALETDNSNSSAQVSTVGQTSREQQ 347
G S + + S+ + G R +G L NS + + G Q
Sbjct: 639 DANSGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQ 698
Query: 348 SKMENAGVNFVVSGREQAQIHNTD---GPKNGNTNSLNLSSPNPMENKGMPF-GMGLGNT 403
S G + E+ + H+ D G ++ +T S S + ++ G + ++
Sbjct: 699 SNRYGGGGRY-----EEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSS 753
Query: 404 SRSTDAPS----QSTGDRKTGSVGSWGAARGPSGTDTVSGQS-NSGNNGNNGKEREDSWK 458
R DA S S+ + G G + RG S G+S N+ + G+N R D +
Sbjct: 754 GRLPDAYSGGHDSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPCR 813
Query: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWK---QPT 515
G + ++ S D N+ + G +DS+ N + ++ G E++ T
Sbjct: 814 GGGRYEE--NRGHSLDANSGGHSPNAYSGGRDSSSNSYDRSHRYGGGGHYEEYRGRSHDT 871
Query: 516 GSDELKIGEWSGPNQPNSSTGAWD---NQKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQ 572
S SG + + + D N G +G GRS ++ G G
Sbjct: 872 HSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDHYGRGGCYEEYQGRSPNAYGGGRGLN 931
Query: 573 STGSNHKAGSSDSHNSGRR--SYRPTHPDCQA 602
S+ ++H G S + G R YR PD +
Sbjct: 932 SSNNSH--GRSHRYGGGGRYEEYRGPSPDAHS 961
Score = 41.6 bits (96), Expect = 0.007
Identities = 105/494 (21%), Positives = 164/494 (33%), Gaps = 119/494 (24%)
Query: 555 APCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLD 614
AP WG T GG ++ S D+ + GR S VL SR D
Sbjct: 314 APVWG-----TPPSYGGGCRYEEYQGNSPDACSEGRSSEA-----LPVVLPDAYSR-DHS 362
Query: 615 PRVLSN--TGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAAT----QTKNSGGWG- 667
P+ S + + D + G+S G ++++ Q+ + GG G
Sbjct: 363 PKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGR 422
Query: 668 --DAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEK-------- 717
+ +S++ +SG A + + G +D + + GGGR +E
Sbjct: 423 YEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDAN 482
Query: 718 ----TPSSW-----NENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKP 768
+P ++ N + S G GG + N+G S N G D T + SS++
Sbjct: 483 SGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPD-THSGGHSSSSNSY 541
Query: 769 VSGWGEGGQNEIGTWG------NGGNASLASKGGWEDCKRSPAW---------------- 806
GG+ G +GG ++ A GG + +S +
Sbjct: 542 GQSHRYGGEGRYEYRGRSHDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDA 601
Query: 807 NETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSW------GGPPPPPPGNVRPSNSSWSS 860
N GR PN+++ H S SW GG G +NS
Sbjct: 602 NSGGRSPNAYSGGHD---------------SSSWSHRYGGGGRYEEYRGRSLDANSGGR- 645
Query: 861 GPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAP 920
SP + S D ++ +G Y L D NS G
Sbjct: 646 ------------------SPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGG---- 683
Query: 921 REPNLPTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWE----EEEDGGVWNTTGSQGS 976
+P DS S + +G G R+ + + GG T S+G
Sbjct: 684 -----RSPDAYSGGHDSSSQSNRYG------GGGRYEEYRGHSLDANSGGRSPDTYSRGH 732
Query: 977 ASSHNSASWGQGGK 990
SS S +G GG+
Sbjct: 733 DSSSQSDHYGGGGR 746
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 55.5 bits (132), Expect = 5e-07
Identities = 49/121 (40%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 1104 PVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPG--LFNVGPQLSP--QQIAML 1159
P QP + P + Q Q P + QFP L P L QL P QQ A+
Sbjct: 441 PQQPPH--PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQ 498
Query: 1160 SQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQR 1219
Q Q+ Q QL Q L Q QQQ LLQ Q++ +Q Q+QQL RM QQQQQQQ
Sbjct: 499 QQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQ-----QQIQQQQLQRM----HQQQQQQQM 549
Query: 1220 Q 1220
Q
Sbjct: 550 Q 550
Score = 37.4 bits (85), Expect = 0.13
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query: 1154 QQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQA-----VRQQQEQQLARMVS 1208
QQ Q Q P L Q ++Q QQQQQ +Q+ Q +QQQ+QQ A
Sbjct: 403 QQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQ 462
Query: 1209 ALQQQ---QQQQQRQPGMKHSPSHPVGP 1233
QQQ QQQ P H P + P
Sbjct: 463 FSQQQLQFPQQQLHPPQQLHRPQQQLQP 490
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/56 (41%), Positives = 26/56 (46%), Gaps = 8/56 (14%)
Query: 1175 LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPSHP 1230
+LQQQQQ Q Q Q + QQ + LQQQQQQQ Q P HP
Sbjct: 400 MLQQQQQAQQQQQQHPVLHLQPQQ--------IMQLQQQQQQQISQQPYPQQPPHP 447
Score = 36.2 bits (82), Expect = 0.28
Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 9/73 (12%)
Query: 1158 MLSQLPQIPQFQLACQLLLQQQQQQQ--LLQNQRKISQAVRQQQEQQLARMV-------S 1208
+ SQ+ P+ + Q QQQQQQ +L Q + ++QQQ+QQ+++
Sbjct: 388 LFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHP 447
Query: 1209 ALQQQQQQQQRQP 1221
QQQQQQQQ P
Sbjct: 448 FSQQQQQQQQAHP 460
Score = 34.7 bits (78), Expect = 0.82
Identities = 34/98 (34%), Positives = 42/98 (42%), Gaps = 27/98 (27%)
Query: 1150 QLSPQQIAMLSQ----LPQIPQFQLACQLLL-------QQQQQQQLLQNQRKISQAVRQQ 1198
QL QQ+A L Q L Q Q Q+ Q L QQQ Q Q + + SQA++ Q
Sbjct: 508 QLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQ 567
Query: 1199 QEQQLARMVSALQQQQQQQQRQPGMKHSPSHPVGPKPH 1236
Q Q QQQQQ+QP P P+ H
Sbjct: 568 VPPQ--------QPPQQQQQQQP--------PPSPQQH 589
Score = 31.6 bits (70), Expect = 7.0
Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 10/89 (11%)
Query: 1151 LSPQQIAMLSQ-----LPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQ---- 1201
L PQQI L Q + Q P Q QQQQQQQ + Q ++ Q+Q
Sbjct: 419 LQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPP 478
Query: 1202 -QLARMVSALQQQQQQQQRQPGMKHSPSH 1229
QL R LQ QQQ Q H
Sbjct: 479 QQLHRPQQQLQPFQQQHALQQQFHQLQQH 507
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 55.5 bits (132), Expect = 5e-07
Identities = 137/654 (20%), Positives = 218/654 (33%), Gaps = 142/654 (21%)
Query: 643 EGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTE--WKDPKNTGGWND 700
+G +D ++ W +AA + G A +S+ G + + P+ + +
Sbjct: 327 KGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQ 386
Query: 701 YKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSN 760
+GG P S+ QG G P QG +G + Q
Sbjct: 387 MGKMRPQPYGGTNPY-----------SQQQGPPSG--PQQGHGYPGQPYGSQTPQRYPMT 433
Query: 761 WESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQH 820
+ A + G Q I +G G + +G ++P +N+ P
Sbjct: 434 MQGRAQSAMGGLSYTQQ--IPPYGQQGPSGYGQQG------QTPYYNQQSPHP------- 478
Query: 821 QQQQPP--QQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGP-QPATPKDEEPSGWEE 877
QQQQPP QQPP P A S+ P P ++ S +S P QP P + P+
Sbjct: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP--PHQQSPA---- 532
Query: 878 PSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAP----REPNLPTPMTSKS 933
P P S + P + + + + PAP ++ P P + +S
Sbjct: 533 PYPSQQSTTQQHPQSQPPYSQPQAQ-----SPYQQQQPQQPAPSTLSQQAAYPQPQSQQS 587
Query: 934 ASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQM 993
+ S Q R P +E ++ GSQ ASS S + +GG++ M
Sbjct: 588 QQTAYSQQ-------------RFPPPQELSQ----DSFGSQ--ASSAPSMTSSKGGQEDM 628
Query: 994 KCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGD 1053
SL + PSS DLS GS+ D +
Sbjct: 629 NLSL-------------------------QSRPSSLPDLS-GSIDDLPMGTE-------- 654
Query: 1054 FNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPS 1113
G P G + S +++ G+ P SP+
Sbjct: 655 ----------GALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPA 704
Query: 1114 LRAQVPPQFISP-QVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAM----LSQLPQIPQF 1168
AQ +SP V + + P SG S + + P ++ IA + + PQ+PQ+
Sbjct: 705 SVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMH--PSMNQSSIAQDRGYMQRNPQMPQY 762
Query: 1169 QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPS 1228
Q + + RQ Q+ + + QQ G ++ P
Sbjct: 763 S----------------SPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQ 806
Query: 1229 HPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGT 1282
+P+ N +PNA P G I G +GG +G G GT
Sbjct: 807 GGYPRQPNY-NALPNA---NYPSAGMAGGINPMG----AGGQMHGQPGIPPYGT 852
Score = 40.8 bits (94), Expect = 0.011
Identities = 77/359 (21%), Positives = 127/359 (35%), Gaps = 50/359 (13%)
Query: 822 QQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSN-SSWSSGPQPATPKDEEPSGWEE--P 878
QQ P QPP QP+A + P P PS S ++ PQP + + ++ + ++ P
Sbjct: 542 QQHPQSQPPYSQPQAQSPYQQQQPQQPA---PSTLSQQAAYPQPQSQQSQQTAYSQQRFP 598
Query: 879 SPQSISRKMDIDDGTSAWGDPNSYNYK------NVNLWDKNS---------QGGPAPREP 923
PQ +S+ G+ A P+ + K N++L + S P E
Sbjct: 599 PPQELSQD---SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEG 655
Query: 924 NLPTPMTSKSASDSKSMQDGWGESD-GPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNS 982
L +++ S S+ Q +S P T P V + S S S
Sbjct: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLS 715
Query: 983 ASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFS---NMGLLSQTEDNPSSKMDLSVGSLSD 1039
+ G QM G +DS M+P Q S + G + + P +LS
Sbjct: 716 PAAVPG--NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSP 773
Query: 1040 KKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGG-----SHGLFGNS 1094
++ + +G + NS G Y +GG ++ N+
Sbjct: 774 RQPSGGQIHTGMGSYQQ------------NSMGSYGPQGGQYGPQGGYPRQPNYNALPNA 821
Query: 1095 TAQSRGLHTPVQPLNSSPSLRAQ--VPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQL 1151
S G+ + P+ + + Q +PP P S N P + N+ PQ+
Sbjct: 822 NYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSH-ASMGNRPYGPNMANMPPQV 879
Score = 37.4 bits (85), Expect = 0.13
Identities = 74/306 (24%), Positives = 98/306 (32%), Gaps = 43/306 (14%)
Query: 1211 QQQQQQQQR------QPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPG---- 1260
QQQQQQQQR Q + +PS P N P T GP P
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGP-PAKRHE 1385
Query: 1261 ---YGSGFSSGGMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGK 1317
Y +S+G A + +Q + V Q N + A A +
Sbjct: 1386 GEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATER 1445
Query: 1318 TRGGSPYNQFDIIPG-DTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPW 1376
G P NQF G D + G PP G ++A Q G W
Sbjct: 1446 RPAGGPQNQFPFQFGRDRVSAPPGTNAQQ----NMPPQMMGGPIQASAE---VAQQGTMW 1498
Query: 1377 KGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYS 1436
+G ++ + GS G A + TD L D G+WP
Sbjct: 1499 QGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHE----------GSWP-- 1546
Query: 1437 ASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISS-RNTTPLPRPPPGL 1495
S + + SA P P P + P +NHI + PLPRP
Sbjct: 1547 -SHGTRQPPYGPSAPVPPMT---RPPPSNYQPP----PSMQNHIPQVSSPAPLPRPMENR 1598
Query: 1496 TNPKPS 1501
T+P S
Sbjct: 1599 TSPSKS 1604
Score = 32.3 bits (72), Expect = 4.1
Identities = 33/140 (23%), Positives = 46/140 (32%), Gaps = 17/140 (12%)
Query: 834 PEASGSWGGPPPPPPGNVRPSNSSW--SSGPQPA-----------TPKDEEPSGWEEPSP 880
P A+ S G PPPPPP ++ + +G + A +E G P
Sbjct: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66
Query: 881 QSISRKMD---IDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDS 937
Q + +++ +G G S KNS G PR P L +T
Sbjct: 67 QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR-PALNNNLTEPPGGGG 125
Query: 938 KSMQDGWGESDGPVTGARHP 957
DG G A P
Sbjct: 126 GGSSDGVGAPPHSAAAALPP 145
Score = 32.0 bits (71), Expect = 5.3
Identities = 71/323 (21%), Positives = 106/323 (32%), Gaps = 44/323 (13%)
Query: 821 QQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPA-TPKDEEPSGWEEPS 879
++ QP QPP P SGS GP P + + P PA TP + P P
Sbjct: 1124 KKSQPKIQPP--SPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIP-----PL 1176
Query: 880 P-QSISRKMDIDDGTSAWGD----------PNSYNYKNVNL--------WDKNSQGGPAP 920
P S S + I D + D PN ++N ++ N +
Sbjct: 1177 PGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSM 1236
Query: 921 REPNLPTPMTSKSASDSKSMQDGWGESDGPVTG--ARHPSWEEEEDGGVWNTTGSQGSAS 978
R+ P S + M D + + GP G A P + GG ++ ++
Sbjct: 1237 RKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPR-QHYPYGGPYDRVRTEPGIG 1295
Query: 979 SHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLS 1038
+ S G + +L N DS M ++ Q + + G+ S
Sbjct: 1296 PEGNMSTG-----APQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS 1350
Query: 1039 DKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQS 1098
F + M + R + PP + G S PY G Q
Sbjct: 1351 GSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYST--------GQGQPQQ 1402
Query: 1099 RGLHTPVQPLNSSPSLRAQVPPQ 1121
+ L P QP +S AQ PQ
Sbjct: 1403 QQL-PPAQPQPASQQQAAQPSPQ 1424
Score = 31.2 bits (69), Expect = 9.1
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 8/63 (12%)
Query: 946 ESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSW 1005
ES+GP G P +E +DG N G G A G GG + LK N ++
Sbjct: 57 ESEGPAVGPPQPLGKELQDGAESNGGGGGGGA--------GSGGGPGAEPDLKNSNGNAG 108
Query: 1006 MNP 1008
P
Sbjct: 109 PRP 111
Score = 31.2 bits (69), Expect = 9.1
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 13/111 (11%)
Query: 762 ESSASKPVSGWGEGGQNEIG-TWGNGGNASLASKG-GWEDCKRSPAWNETGRQPN---SW 816
++SA G G+N++ + N + A +G + R+ T ++ N SW
Sbjct: 1486 QASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSW 1545
Query: 817 NKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATP 867
H +QPP P P P + PPP N +P S + PQ ++P
Sbjct: 1546 -PSHGTRQPPYGPSAPVPPMTR-------PPPSNYQPPPSMQNHIPQVSSP 1588
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 55.5 bits (132), Expect = 5e-07
Identities = 137/654 (20%), Positives = 218/654 (33%), Gaps = 142/654 (21%)
Query: 643 EGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGELSASTE--WKDPKNTGGWND 700
+G +D ++ W +AA + G A +S+ G + + P+ + +
Sbjct: 327 KGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQ 386
Query: 701 YKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSN 760
+GG P S+ QG G P QG +G + Q
Sbjct: 387 MGKMRPQPYGGTNPY-----------SQQQGPPSG--PQQGHGYPGQPYGSQTPQRYPMT 433
Query: 761 WESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQH 820
+ A + G Q I +G G + +G ++P +N+ P
Sbjct: 434 MQGRAQSAMGGLSYTQQ--IPPYGQQGPSGYGQQG------QTPYYNQQSPHP------- 478
Query: 821 QQQQPP--QQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGP-QPATPKDEEPSGWEE 877
QQQQPP QQPP P A S+ P P ++ S +S P QP P + P+
Sbjct: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQP--PHQQSPA---- 532
Query: 878 PSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAP----REPNLPTPMTSKS 933
P P S + P + + + + PAP ++ P P + +S
Sbjct: 533 PYPSQQSTTQQHPQSQPPYSQPQAQ-----SPYQQQQPQQPAPSTLSQQAAYPQPQSQQS 587
Query: 934 ASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQM 993
+ S Q R P +E ++ GSQ ASS S + +GG++ M
Sbjct: 588 QQTAYSQQ-------------RFPPPQELSQ----DSFGSQ--ASSAPSMTSSKGGQEDM 628
Query: 994 KCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGD 1053
SL + PSS DLS GS+ D +
Sbjct: 629 NLSL-------------------------QSRPSSLPDLS-GSIDDLPMGTE-------- 654
Query: 1054 FNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGNSTAQSRGLHTPVQPLNSSPS 1113
G P G + S +++ G+ P SP+
Sbjct: 655 ----------GALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPA 704
Query: 1114 LRAQVPPQFISP-QVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAM----LSQLPQIPQF 1168
AQ +SP V + + P SG S + + P ++ IA + + PQ+PQ+
Sbjct: 705 SVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMH--PSMNQSSIAQDRGYMQRNPQMPQY 762
Query: 1169 QLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQPGMKHSPS 1228
Q + + RQ Q+ + + QQ G ++ P
Sbjct: 763 S----------------SPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQ 806
Query: 1229 HPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSGGMDYGMVGGKEAGT 1282
+P+ N +PNA P G I G +GG +G G GT
Sbjct: 807 GGYPRQPNY-NALPNA---NYPSAGMAGGINPMG----AGGQMHGQPGIPPYGT 852
Score = 40.8 bits (94), Expect = 0.011
Identities = 77/359 (21%), Positives = 127/359 (35%), Gaps = 50/359 (13%)
Query: 822 QQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSN-SSWSSGPQPATPKDEEPSGWEE--P 878
QQ P QPP QP+A + P P PS S ++ PQP + + ++ + ++ P
Sbjct: 542 QQHPQSQPPYSQPQAQSPYQQQQPQQPA---PSTLSQQAAYPQPQSQQSQQTAYSQQRFP 598
Query: 879 SPQSISRKMDIDDGTSAWGDPNSYNYK------NVNLWDKNS---------QGGPAPREP 923
PQ +S+ G+ A P+ + K N++L + S P E
Sbjct: 599 PPQELSQD---SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEG 655
Query: 924 NLPTPMTSKSASDSKSMQDGWGESD-GPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNS 982
L +++ S S+ Q +S P T P V + S S S
Sbjct: 656 ALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLS 715
Query: 983 ASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFS---NMGLLSQTEDNPSSKMDLSVGSLSD 1039
+ G QM G +DS M+P Q S + G + + P +LS
Sbjct: 716 PAAVPG--NQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSP 773
Query: 1040 KKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGG-----SHGLFGNS 1094
++ + +G + NS G Y +GG ++ N+
Sbjct: 774 RQPSGGQIHTGMGSYQQ------------NSMGSYGPQGGQYGPQGGYPRQPNYNALPNA 821
Query: 1095 TAQSRGLHTPVQPLNSSPSLRAQ--VPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQL 1151
S G+ + P+ + + Q +PP P S N P + N+ PQ+
Sbjct: 822 NYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSH-ASMGNRPYGPNMANMPPQV 879
Score = 32.3 bits (72), Expect = 4.1
Identities = 33/140 (23%), Positives = 46/140 (32%), Gaps = 17/140 (12%)
Query: 834 PEASGSWGGPPPPPPGNVRPSNSSW--SSGPQPA-----------TPKDEEPSGWEEPSP 880
P A+ S G PPPPPP ++ + +G + A +E G P
Sbjct: 7 PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66
Query: 881 QSISRKMD---IDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPTPMTSKSASDS 937
Q + +++ +G G S KNS G PR P L +T
Sbjct: 67 QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPR-PALNNNLTEPPGGGG 125
Query: 938 KSMQDGWGESDGPVTGARHP 957
DG G A P
Sbjct: 126 GGSSDGVGAPPHSAAAALPP 145
Score = 32.0 bits (71), Expect = 5.3
Identities = 48/250 (19%), Positives = 83/250 (33%), Gaps = 44/250 (17%)
Query: 1293 MEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSP 1352
M+G + + ++M + G + P T +P++Q +PG + G D++
Sbjct: 1141 MQGPQTPQSTSSSMAEGGDLKPP--TPASTPHSQIPPLPGMSRSNSVG-IQDAFNDGSDS 1197
Query: 1353 PTNKIGSKSSNASWPPE-----------FQPGVPWKGIQNIDPESDPYVTPGSV------ 1395
K S + N + P ++P G P SDP+++ G
Sbjct: 1198 TFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMG 1257
Query: 1396 ----------LGGTATSPIVDTDH-----QLLRDNTTGSNSSLNTSLPSPGAWP------ 1434
LG A P + ++ + G +++T P P P
Sbjct: 1258 DPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSG 1317
Query: 1435 -YSASDNSFTNVHSTSAKFPDYKSTWSPD--PIGHNPTHLSNKMWKNHISSRNTTPLPRP 1491
YS S + Y + +S P G M++ + PLPRP
Sbjct: 1318 MYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRP 1377
Query: 1492 PPGLTNPKPS 1501
T+P S
Sbjct: 1378 MENRTSPSKS 1387
Score = 31.2 bits (69), Expect = 9.1
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 8/63 (12%)
Query: 946 ESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKGGNNDSW 1005
ES+GP G P +E +DG N G G A G GG + LK N ++
Sbjct: 57 ESEGPAVGPPQPLGKELQDGAESNGGGGGGGA--------GSGGGPGAEPDLKNSNGNAG 108
Query: 1006 MNP 1008
P
Sbjct: 109 PRP 111
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 55.1 bits (131), Expect = 6e-07
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 1101 LHTPVQPLNSSPSLRAQVPPQFISPQVSA---SMLKQFPNSGLSPGLFNVGPQ--LSPQQ 1155
+ P+ + +S ++ A +P +P +S+ +M+ P++ +SP + Q L QQ
Sbjct: 385 MRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQ 444
Query: 1156 IAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQ 1215
Q+ Q+ Q QL + QQ QQQ Q+ + Q QQQ+Q L + ++ Q QQQ
Sbjct: 445 QQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQ 504
Query: 1216 QQQR-QPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGS 1263
QQR Q H P P + V + Q PIP GS
Sbjct: 505 LQQRLQLQQLQHMQHQSQPSPRQHSPVAS---------QITSPIPAIGS 544
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 55.1 bits (131), Expect = 6e-07
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 1101 LHTPVQPLNSSPSLRAQVPPQFISPQVSA---SMLKQFPNSGLSPGLFNVGPQ--LSPQQ 1155
+ P+ + +S ++ A +P +P +S+ +M+ P++ +SP + Q L QQ
Sbjct: 390 MRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQ 449
Query: 1156 IAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQ 1215
Q+ Q+ Q QL + QQ QQQ Q+ + Q QQQ+Q L + ++ Q QQQ
Sbjct: 450 QQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQ 509
Query: 1216 QQQR-QPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGS 1263
QQR Q H P P + V + Q PIP GS
Sbjct: 510 LQQRLQLQQLQHMQHQSQPSPRQHSPVAS---------QITSPIPAIGS 549
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.125 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,415,782
Number of Sequences: 37866
Number of extensions: 5473078
Number of successful extensions: 45644
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 398
Number of HSP's successfully gapped in prelim test: 1069
Number of HSP's that attempted gapping in prelim test: 24668
Number of HSP's gapped (non-prelim): 13957
length of query: 1723
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1607
effective length of database: 13,855,062
effective search space: 22265084634
effective search space used: 22265084634
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.