Search of human proteins with 148277620

Search of human proteins with 148277620

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148277620 type I hair keratin KA35 [Homo sapiens]
         (491 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148277620 type I hair keratin KA35 [Homo sapiens]                  994   0.0  
gi|4504927 keratin 36 [Homo sapiens]                                  491   e-139
gi|116488398 keratin 32 [Homo sapiens]                                467   e-131
gi|94538345 keratin 35 [Homo sapiens]                                 462   e-130
gi|14917115 keratin 31 [Homo sapiens]                                 462   e-130
gi|14917117 keratin 33A [Homo sapiens]                                455   e-128
gi|14917119 keratin 34 [Homo sapiens]                                 447   e-125
gi|10337581 type I hair keratin 3B [Homo sapiens]                     446   e-125
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  433   e-121
gi|15431318 keratin 38 [Homo sapiens]                                 394   e-109
gi|55770882 keratin 37 [Homo sapiens]                                 385   e-107
gi|4557701 keratin 17 [Homo sapiens]                                  328   9e-90
gi|15431310 keratin 14 [Homo sapiens]                                 326   3e-89
gi|24430190 keratin 15 [Homo sapiens]                                 320   2e-87
gi|24234699 keratin 19 [Homo sapiens]                                 317   2e-86
gi|131412225 keratin 13 isoform a [Homo sapiens]                      313   3e-85
gi|24430192 keratin 16 [Homo sapiens]                                 313   3e-85
gi|131412228 keratin 13 isoform b [Homo sapiens]                      310   2e-84
gi|195972866 keratin 10 [Homo sapiens]                                289   5e-78
gi|4557699 keratin 12 [Homo sapiens]                                  283   3e-76
gi|153945736 keratin 27 [Homo sapiens]                                276   3e-74
gi|192807292 keratin 24 [Homo sapiens]                                274   1e-73
gi|27894337 keratin 20 [Homo sapiens]                                 273   2e-73
gi|114431246 keratin 25D [Homo sapiens]                               271   8e-73
gi|31559829 keratin 25 [Homo sapiens]                                 271   1e-72
gi|55956899 keratin 9 [Homo sapiens]                                  270   2e-72
gi|40354195 keratin 18 [Homo sapiens]                                 261   1e-69
gi|4557888 keratin 18 [Homo sapiens]                                  261   1e-69
gi|31559815 keratin 26 [Homo sapiens]                                 248   7e-66
gi|27894339 keratin 23 [Homo sapiens]                                 225   8e-59

>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  994 bits (2570), Expect = 0.0
 Identities = 491/491 (100%), Positives = 491/491 (100%)

Query: 1   MDTKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQ 60
           MDTKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQ
Sbjct: 1   MDTKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQ 60

Query: 61  PTPRFCRKPIYLMNNFNARFSLDDCSWYGEGINSNEKETMQILNERLANYLQKVRMLERE 120
           PTPRFCRKPIYLMNNFNARFSLDDCSWYGEGINSNEKETMQILNERLANYLQKVRMLERE
Sbjct: 61  PTPRFCRKPIYLMNNFNARFSLDDCSWYGEGINSNEKETMQILNERLANYLQKVRMLERE 120

Query: 121 NAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADD 180
           NAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADD
Sbjct: 121 NAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADD 180

Query: 181 LRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINS 240
           LRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINS
Sbjct: 181 LRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINS 240

Query: 241 LQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVT 300
           LQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVT
Sbjct: 241 LQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVT 300

Query: 301 SSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDN 360
           SSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDN
Sbjct: 301 SSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDN 360

Query: 361 LEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSP 420
           LEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSP
Sbjct: 361 LEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSP 420

Query: 421 WTSCKSGAIESTAPACTSSSPCSLKEHCSACGPLSRILVKICTITKEIKDGKVISSYEHV 480
           WTSCKSGAIESTAPACTSSSPCSLKEHCSACGPLSRILVKICTITKEIKDGKVISSYEHV
Sbjct: 421 WTSCKSGAIESTAPACTSSSPCSLKEHCSACGPLSRILVKICTITKEIKDGKVISSYEHV 480

Query: 481 QPCFIIRPAKV 491
           QPCFIIRPAKV
Sbjct: 481 QPCFIIRPAKV 491


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  491 bits (1263), Expect = e-139
 Identities = 273/486 (56%), Positives = 335/486 (68%), Gaps = 28/486 (5%)

Query: 1   MDTKGCTTTNSPSTP---CQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQ 57
           M T+ CT T S  +    C     I+ VS+I S   C    L       AG    I   +
Sbjct: 1   MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSL-------AGAAGYISSAR 53

Query: 58  GCQPTPRFCRKPIYLMNNFNARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVRM 116
                   C    YL +  +    +    W+ EG  N +EKETMQ LN+RLANYL+KVR 
Sbjct: 54  SGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQ 113

Query: 117 LERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKL 176
           LERENAELES+IQE    ++P +CPDY SY+ TIE+ QQKIL TK+EN+RLV QIDN KL
Sbjct: 114 LERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKL 173

Query: 177 TADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKE 236
            ADD R KYE E+SLRQLVE+D NGL++IL+ LTL KADLEAQV+SLKEEL+CLK NH+E
Sbjct: 174 AADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEE 233

Query: 237 EINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQ 296
           E++ L+CQLG+RL++EV AAP  DLN++L++MRCQYE ++E NR+DVE WFNTQ EELNQ
Sbjct: 234 EVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQ 293

Query: 297 QVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQS 356
           QVV+SS+Q QCCQ EIIELRR+VN LE+ELQAQH MR+S E  L ETEARY++ L Q+Q 
Sbjct: 294 QVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQC 353

Query: 357 LIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKC 416
           LI N+EAQL+EIRC LERQNQEY++LLDVK+RLE EI TYR LLE  D K P  P AT C
Sbjct: 354 LISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATAC 413

Query: 417 EPSPWTSCKSGAIESTAPA-CTSSSPCSLKEHCSACGPLSRILVKICTITKEIKDGKVIS 475
           +P          + S  P  C  S PC+         P  ++  +I TIT+EI+DGKVIS
Sbjct: 414 KPVI-------RVPSVPPVPCVPSVPCT---------PAPQVGTQIRTITEEIRDGKVIS 457

Query: 476 SYEHVQ 481
           S EHVQ
Sbjct: 458 SREHVQ 463


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  467 bits (1201), Expect = e-131
 Identities = 252/430 (58%), Positives = 312/430 (72%), Gaps = 19/430 (4%)

Query: 3   TKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQPT 62
           T  C  TN+     ++C R  +V   SS   C P       CQP   +  +     C PT
Sbjct: 2   TSSCCVTNNLQASLKSCPRPASVC--SSGVNCRPELCLGYVCQPMACLPSV-----CLPT 54

Query: 63  ---PRFCRKPIYLMNNFNARF----SLDDCSWYGEG-INSNEKETMQILNERLANYLQKV 114
              P  C    YL ++  A      S+   SWY EG  N NEKETMQ LN+RLA+YL +V
Sbjct: 55  TFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRV 114

Query: 115 RMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNT 174
           R LE+ENAELES+IQE S+ ++  + PDY S++ TIEELQQKILCTKAEN+R+V  IDN 
Sbjct: 115 RQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNA 174

Query: 175 KLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNH 234
           KL ADD RAKYEAE+++RQLVE+D NGL++IL+ LTL KADLEAQV+SLKEEL+CLK NH
Sbjct: 175 KLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNH 234

Query: 235 KEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEEL 294
           +EE+ SL+CQLG+RL+IEV AAP  DL +VL+EMRCQYE ++E NR+DVE+WFN Q+EEL
Sbjct: 235 EEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEEL 294

Query: 295 NQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQI 354
           NQQV TSS+Q Q  Q +II+LRR+VNTLE+ELQAQH +RDS E  LTE+EARY++ L Q+
Sbjct: 295 NQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQM 354

Query: 355 QSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPC----Y 410
           Q +I N+EAQLAEIR  LERQNQEY++LLDV++RLE EI TYRSLLE+ D K PC     
Sbjct: 355 QCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCST 414

Query: 411 PRATKCEPSP 420
           P  T C PSP
Sbjct: 415 PSCTTCVPSP 424


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  462 bits (1190), Expect = e-130
 Identities = 236/368 (64%), Positives = 287/368 (77%), Gaps = 7/368 (1%)

Query: 87  WYGEGI-NSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLS 145
           W+GEGI   NEKETMQ LN+RLA YL+KVR LE+ENA LES+I+E   +++P +CPDY S
Sbjct: 87  WFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQS 146

Query: 146 YYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQI 205
           Y+ TIEELQ+K LC+KAEN+RLV +IDN KL ADD R KYE EVSLRQLVESD NGL++I
Sbjct: 147 YFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRI 206

Query: 206 LNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVL 265
           L+ LTL K+DLEAQV+SLKEELLCLK NH+EE+NSL+CQLG+RL++EV AAP  DLN+VL
Sbjct: 207 LDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVL 266

Query: 266 QEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVE 325
           +EMRCQYE ++E NR+D E W +TQ EELNQQVV+SS+Q Q CQ EIIELRR+VN LE+E
Sbjct: 267 EEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIE 326

Query: 326 LQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDV 385
           LQAQH MRD+ E  L ETEARY++ L Q+Q +I N+EAQLAEIR  LERQNQEY++LLDV
Sbjct: 327 LQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDV 386

Query: 386 KSRLECEITTYRSLLESSDGKRPCYPRATKCEP--SPWTSCKSGAIESTAPACTSSSPCS 443
           ++RLECEI TYR LLES D K PC P    C P  SP  SC      ++     + + CS
Sbjct: 387 RARLECEINTYRGLLESEDSKLPCNP----CAPDYSPSKSCLPCLPAASCGPSAARTNCS 442

Query: 444 LKEHCSAC 451
            +  C  C
Sbjct: 443 PRPICVPC 450


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  462 bits (1189), Expect = e-130
 Identities = 238/382 (62%), Positives = 298/382 (78%), Gaps = 3/382 (0%)

Query: 77  NARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKE 135
           N   ++ +C+W+ EG  N +EKETMQ LN+RLA+YL+KVR LER+NAELE+ I+E S ++
Sbjct: 36  NIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQ 95

Query: 136 LPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLV 195
            P+LCP Y SY+ TIEELQQKILCTK+EN+RLV QIDN KL ADD R KY+ E+SLRQLV
Sbjct: 96  EPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLV 155

Query: 196 ESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTA 255
           ESD NGL++IL+ LTL K+DLEAQV+SLKEELLCLK+NH++E+N+L+CQLG+RL++EV A
Sbjct: 156 ESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDA 215

Query: 256 APSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIEL 315
           AP+ DLN+VL E R QYE ++ETNR++VEQWF TQ EELN+QVV+SS+Q Q  Q EIIEL
Sbjct: 216 APTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIEL 275

Query: 316 RRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQ 375
           RR+VN LE+ELQAQH +RDS E  LTE+EARY++ L+Q+QSLI N+E+QLAEIR  LERQ
Sbjct: 276 RRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQ 335

Query: 376 NQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPS-PWTSCKSGAIESTAP 434
           NQEY++LLDV++RLECEI TYRSLLES D   P  P AT    S P   C S    S  P
Sbjct: 336 NQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVP 395

Query: 435 ACTSSSPCSLKEHCSACGPLSR 456
                +PC+ +  C  C    R
Sbjct: 396 P-APCTPCAPRPRCGPCNSFVR 416


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  455 bits (1171), Expect = e-128
 Identities = 233/376 (61%), Positives = 295/376 (78%), Gaps = 13/376 (3%)

Query: 77  NARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKE 135
           N   ++ +C+W+ EG  N +EKETMQ LN+RLA+YL+KVR LER+NAELE+ I+E S ++
Sbjct: 36  NIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQ 95

Query: 136 LPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLV 195
            P++C  Y SY+ TIEELQQKILC+K+EN+RLV QIDN KL +DD R KYE E+SLRQLV
Sbjct: 96  EPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLV 155

Query: 196 ESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTA 255
           ESD NGL++IL+ LTL ++DLEAQV+SLKEELLCLK NH++E+N+L+CQLG+RL++EV A
Sbjct: 156 ESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDA 215

Query: 256 APSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIEL 315
           AP+ DLNQVL E R QYE ++ETNR++VEQWF TQ EELN+QVV+SS+Q Q  Q EIIEL
Sbjct: 216 APTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIEL 275

Query: 316 RRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQ 375
           RR+VN LE+ELQAQH +RDS E  LTE+EARY++ L+Q+Q LI N+E+QLAEIR  LERQ
Sbjct: 276 RRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQ 335

Query: 376 NQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPA 435
           NQEY++LLDV++RLECEI TYRSLLES D K P  P AT           +   +ST P 
Sbjct: 336 NQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCAT----------TNACDKSTGPC 385

Query: 436 CTSSSPCSLKEHCSAC 451
              S+PC L+  C  C
Sbjct: 386 I--SNPCGLRARCGPC 399


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  447 bits (1149), Expect = e-125
 Identities = 222/339 (65%), Positives = 278/339 (82%), Gaps = 1/339 (0%)

Query: 77  NARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKE 135
           N   ++ +C+W+ EG  N +EKETMQ LN+RLA+YL+KVR LER+NAELE  IQE S ++
Sbjct: 78  NIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQ 137

Query: 136 LPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLV 195
            P+LCP Y SY+ TIEELQQKILC KAEN+RLV  IDN KL +DD R+KY+ E SLR LV
Sbjct: 138 EPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLV 197

Query: 196 ESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTA 255
           ESD N +++IL+ LTL K+DLE+QV+SL+EEL+CLK NH+EE+N+L+ QLG+RL++EV  
Sbjct: 198 ESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDT 257

Query: 256 APSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIEL 315
           AP+ DLNQVL E R QYE ++E NR++VEQWF TQ EELN+QVV+SS+Q Q CQ EIIEL
Sbjct: 258 APTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIEL 317

Query: 316 RRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQ 375
           RR+VN LE+ELQAQH +RDS E  LTE+EA Y++ L+Q+QSLI N+E+QLAEIRC LERQ
Sbjct: 318 RRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQ 377

Query: 376 NQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRAT 414
           NQEY++LLDV++RLECEI TYRSLLES D K PC P AT
Sbjct: 378 NQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCAT 416


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  446 bits (1147), Expect = e-125
 Identities = 230/376 (61%), Positives = 292/376 (77%), Gaps = 13/376 (3%)

Query: 77  NARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKE 135
           N   ++ +C+W+ EG  N +EKETMQ LN+RLA+YL+KVR LER+NAELE+ I+E S ++
Sbjct: 36  NIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQ 95

Query: 136 LPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLV 195
            P+LCP Y SY+ TIEELQQKILC+K+EN+RLV QIDN KL ADD R KY+ E SLRQLV
Sbjct: 96  EPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLV 155

Query: 196 ESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTA 255
           ESD N L++IL+ LTL ++DLEAQ++SLKEELL LK NH++E+N+L+CQLG+RL++EV A
Sbjct: 156 ESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDA 215

Query: 256 APSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIEL 315
           AP+ DLNQVL E R QYE ++ETNR++VEQWF TQ EELN+QVV+SS+Q Q  Q EIIEL
Sbjct: 216 APAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIEL 275

Query: 316 RRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQ 375
           RR+VN LE+ELQAQH +R S E  LTE+EARY++ L+Q+QSLI N+E+QLAEIR  LERQ
Sbjct: 276 RRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQ 335

Query: 376 NQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPA 435
           NQEY++LLDV++RLECEI TYRSLLES D K P  P AT           + A E    +
Sbjct: 336 NQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCAT-----------TNACEKPIGS 384

Query: 436 CTSSSPCSLKEHCSAC 451
           C  ++PC  +  C  C
Sbjct: 385 CV-TNPCGPRSRCGPC 399


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  433 bits (1114), Expect = e-121
 Identities = 224/447 (50%), Positives = 300/447 (67%), Gaps = 19/447 (4%)

Query: 3   TKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQPT 62
           T  C++T+     C   S     S+ S    C PG    + CQ    + R     GC   
Sbjct: 2   TSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCL-- 59

Query: 63  PRFCRKPIYLMNNFNARFSLDDCSWYGEGI-NSNEKETMQILNERLANYLQKVRMLEREN 121
                 P Y   + N+   + +C+W  +G+  SNEKETMQ LN+RLA+YL+KVR LE  N
Sbjct: 60  -----LPCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETN 114

Query: 122 AELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDL 181
           AELES+IQE+  +++P++CPDY  Y+ TIE+LQQKILCTKAENSRL  Q+DN KL  DD 
Sbjct: 115 AELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDF 174

Query: 182 RAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSL 241
           ++KYE+E+SLRQL+E+D + L  IL  LTL K+DLEA V+SLKE+LLCLK NH+EE+N L
Sbjct: 175 KSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLL 234

Query: 242 QCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTS 301
           + QLG+RL +E+  AP+ DLN+VL EMRCQ E ++  NR++ E+W   Q EELNQQ ++S
Sbjct: 235 REQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSS 294

Query: 302 SQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNL 361
           ++Q Q CQ EI+EL+R+ + LE+ELQAQ  + +S EC + ETEA+Y++ L QIQ LIDNL
Sbjct: 295 AEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNL 354

Query: 362 EAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPW 421
           E QLAEIRC LERQNQEY++LLDVK+RLE EI TY  LL+S D +  C P +T C  S  
Sbjct: 355 ENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSS-- 412

Query: 422 TSCKSGAIESTAPACTSSSPCSLKEHC 448
                    +T   C++   C+++  C
Sbjct: 413 ---------NTCEPCSAYVICTVENCC 430


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  394 bits (1012), Expect = e-109
 Identities = 232/458 (50%), Positives = 290/458 (63%), Gaps = 32/458 (6%)

Query: 10  NSPSTP--CQNCSRITNVSTISSNNGCHPGGLTVNNCQP------AGHVLRI-----PWD 56
           +S S P  C       NVS    + GC PG     N  P        H  R+     P  
Sbjct: 6   SSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEA--NIAPMCLLANVAHANRVRVGSTPLG 63

Query: 57  QGCQPTPRFCRKPIYLMNNFNARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVR 115
           +     P  C     L    +   ++  C  YGE  +N +EKETMQ LN+RLANYL+KVR
Sbjct: 64  RPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVR 123

Query: 116 MLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTK 175
            LE+ENAELE+ + E S      +CPDY SY+ TIEELQQKILC+KAEN+RL+ QIDN K
Sbjct: 124 QLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAK 183

Query: 176 LTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHK 235
           L ADD R K E+E SLRQLVE+D  G +++L+  TL KADLEAQ +SLKEE L LK+NH+
Sbjct: 184 LAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHE 243

Query: 236 EEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELN 295
           +E+  L+ QLGE+L IE+   P+ DLN+VL EMR QYE ++ETNR+DVEQWF  Q E ++
Sbjct: 244 QEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGIS 303

Query: 296 QQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQ 355
            Q ++ S++ QCCQ EI+ELR +VN LEVE QAQH ++D  +  L E E R+   L Q+Q
Sbjct: 304 LQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQ 363

Query: 356 SLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATK 415
           SLI N+E QL+EIR  LERQNQEY++LLDVK+RLE EI TYR+LLES D K PC P    
Sbjct: 364 SLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNP---- 419

Query: 416 CEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSACGP 453
           C  SP  SC       TAP C     C     C+ CGP
Sbjct: 420 CSTSP--SC------VTAP-CAPRPSCG---PCTTCGP 445


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  385 bits (990), Expect = e-107
 Identities = 204/353 (57%), Positives = 259/353 (73%), Gaps = 5/353 (1%)

Query: 85  CSWYGEG-INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDY 143
           C  YG+  +N +EKETM+ LN+RLANYL+KVR LE+ENAELE+ + E S      +CPDY
Sbjct: 92  CGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDY 151

Query: 144 LSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLK 203
            SY+ TIEELQQKILC+KAEN+RL+ QIDN KL ADD R K E+E SL QLVE+D  G +
Sbjct: 152 QSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQ 211

Query: 204 QILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQ 263
           ++L+  TL KADLEAQ +SLKEE L LK+NH++E+  L+ QLGE+  IE+   P+ DLN+
Sbjct: 212 KLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNR 271

Query: 264 VLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLE 323
           VL EMR QYE ++ETN +DVEQWF  Q E ++ Q ++ S++ QCCQ EI+ELR +VN LE
Sbjct: 272 VLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALE 331

Query: 324 VELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILL 383
           VE QAQH ++D  +  L E E RY   L Q+QSLI NLE QL+EIR  LERQNQEY++LL
Sbjct: 332 VERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLL 391

Query: 384 DVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKS-GAIESTAPA 435
           DVK+RLE EI TYR+LLES D K PC P +T   P+  TSC S G +   +P+
Sbjct: 392 DVKARLENEIATYRNLLESEDCKLPCNPCST---PASCTSCPSCGPVTGGSPS 441


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  328 bits (840), Expect = 9e-90
 Identities = 183/385 (47%), Positives = 247/385 (64%), Gaps = 41/385 (10%)

Query: 96  EKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQ 155
           EK TMQ LN+RLA+YL KVR LE  N ELE KI++   ++ P    DY  YY TIEELQ 
Sbjct: 84  EKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQN 143

Query: 156 KILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKAD 215
           KIL    +N+ ++ QIDN +L ADD R K+E E +LR  VE+D NGL+++L+ LTL +AD
Sbjct: 144 KILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARAD 203

Query: 216 LEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPI 275
           LE Q+++LKEEL  LK NH+EE+N+L+ Q+G  +++E+ AAP  DL+++L EMR QYE +
Sbjct: 204 LEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKM 263

Query: 276 METNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDS 335
            E NRKD E WF ++ EELN++V T+S+  Q  + EI ELRR++  LE+ELQ+Q  M+ S
Sbjct: 264 AEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKAS 323

Query: 336 QECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITT 395
            E  L ETE RY   L+QIQ LI ++E QLA++RC +E+QNQEY+ILLDVK+RLE EI T
Sbjct: 324 LEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIAT 383

Query: 396 YRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSACGPLS 455
           YR LLE  D         T+ +  P T+                                
Sbjct: 384 YRRLLEGEDA------HLTQYKKEPVTT-------------------------------- 405

Query: 456 RILVKICTITKEIKDGKVISSYEHV 480
               ++ TI +E++DGKVISS E V
Sbjct: 406 ---RQVRTIVEEVQDGKVISSREQV 427


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  326 bits (835), Expect = 3e-89
 Identities = 182/393 (46%), Positives = 255/393 (64%), Gaps = 33/393 (8%)

Query: 89  GEGIN-SNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYY 147
           G+G+   +EK TMQ LN+RLA+YL KVR LE  NA+LE KI++   ++ P    DY  Y+
Sbjct: 107 GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYF 166

Query: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207
            TIE+L+ KIL    +N+ ++ QIDN +L ADD R KYE E++LR  VE+D NGL+++L+
Sbjct: 167 KTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLD 226

Query: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267
            LTL +ADLE Q++SLKEEL  LK NH+EE+N+L+ Q+G  +++E+ AAP  DL+++L E
Sbjct: 227 ELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNE 286

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           MR QYE + E NRKD E+WF T+ EELN++V T+S+  Q  + EI ELRR++  LE+ELQ
Sbjct: 287 MRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQ 346

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +Q  M+ S E  L ET+ RY   L QIQ +I ++E QLA++RC +E+QNQEY+ILLDVK+
Sbjct: 347 SQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKT 406

Query: 388 RLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEH 447
           RLE EI TYR LLE  D                 +S  S   +S+    +SS        
Sbjct: 407 RLEQEIATYRRLLEGEDAHLS-------------SSQFSSGSQSSRDVTSSSR------- 446

Query: 448 CSACGPLSRILVKICTITKEIKDGKVISSYEHV 480
                       +I T   ++ DGKV+S++E V
Sbjct: 447 ------------QIRTKVMDVHDGKVVSTHEQV 467


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  320 bits (820), Expect = 2e-87
 Identities = 168/321 (52%), Positives = 226/321 (70%), Gaps = 3/321 (0%)

Query: 89  GEG--INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP-DYLS 145
           G+G  ++ NEK TMQ LN+RLA+YL KVR LE  NA+LE KI +   K+ P     DY  
Sbjct: 96  GDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQ 155

Query: 146 YYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQI 205
           Y+ TIEEL+ KI+ T  +NSR++ +IDN +L ADD R KYE E++LRQ VE+D NGL+++
Sbjct: 156 YFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRV 215

Query: 206 LNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVL 265
           L+ LTL + DLE Q++ L EEL  LK NH+EE+     QL  ++++E+ AAP  DL +VL
Sbjct: 216 LDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVL 275

Query: 266 QEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVE 325
            EMR QYE + E NR+DVE WF ++ EELN++V ++++  Q  + EI +LRR++  LE+E
Sbjct: 276 AEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIE 335

Query: 326 LQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDV 385
           LQ+Q  M+   E  L ETE RY   L QIQ LI  LEAQL+E+RC +E QNQEY++LLD+
Sbjct: 336 LQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDI 395

Query: 386 KSRLECEITTYRSLLESSDGK 406
           K+RLE EI TYRSLLE  D K
Sbjct: 396 KTRLEQEIATYRSLLEGQDAK 416


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  317 bits (811), Expect = 2e-86
 Identities = 164/310 (52%), Positives = 221/310 (71%)

Query: 95  NEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQ 154
           NEK TMQ LN+RLA+YL KVR LE  N ELE KI++   K+ P    DY  YYTTI++L+
Sbjct: 79  NEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLR 138

Query: 155 QKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKA 214
            KIL    ENSR+V QIDN +L ADD R K+E E +LR  VE+D NGL+++L+ LTL + 
Sbjct: 139 DKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLART 198

Query: 215 DLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEP 274
           DLE Q++ LKEEL  LK NH+EEI++L+ Q+G ++ +EV +AP  DL ++L +MR QYE 
Sbjct: 199 DLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEV 258

Query: 275 IMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRD 334
           + E NRKD E WF ++ EELN++V   ++Q Q  + E+ +LRR++  LE+ELQ+Q  M+ 
Sbjct: 259 MAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKA 318

Query: 335 SQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEIT 394
           + E  L ETEAR+ A L  IQ+LI  +EAQL ++R   ERQNQEY+ L+D+KSRLE EI 
Sbjct: 319 ALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIA 378

Query: 395 TYRSLLESSD 404
           TYRSLLE  +
Sbjct: 379 TYRSLLEGQE 388


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  313 bits (801), Expect = 3e-85
 Identities = 170/362 (46%), Positives = 239/362 (66%), Gaps = 13/362 (3%)

Query: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP-DYLSYYTTI 150
           +  NEK TMQ LN+RLA+YL+KVR LE  NA+LE KI++   K+ P     DY  YY TI
Sbjct: 100 LTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTI 159

Query: 151 EELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLT 210
           EEL+ KIL    EN+R++ +IDN +L ADD R KYE E++LRQ VE+D NGL+++L+ LT
Sbjct: 160 EELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELT 219

Query: 211 LGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRC 270
           L K DLE Q++SL EEL  +K NH+EE+     Q+  ++++E+ A P  DL +VL EMR 
Sbjct: 220 LSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMRE 279

Query: 271 QYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQH 330
           QYE + E NR+D E+WF+ +  ELN++V T++   Q  + EI ELRR++  LE+ELQ+Q 
Sbjct: 280 QYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQL 339

Query: 331 RMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLE 390
            M+   E  + ETE RY   L QIQ LI ++EAQL+E+R  +E QNQEY++LLD+K+RLE
Sbjct: 340 SMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLE 399

Query: 391 CEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSA 450
            EI TYRSLLE  D K   +P +            +G++   + + T++S  S+    +A
Sbjct: 400 QEIATYRSLLEGQDAKMIGFPSS------------AGSVSPRSTSVTTTSSASVTTTSNA 447

Query: 451 CG 452
            G
Sbjct: 448 SG 449


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  313 bits (801), Expect = 3e-85
 Identities = 169/361 (46%), Positives = 240/361 (66%), Gaps = 3/361 (0%)

Query: 89  GEGIN-SNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYY 147
           G+G+   +EK TMQ LN+RLA+YL KVR LE  NA+LE KI++   ++ P    DY  Y+
Sbjct: 109 GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYF 168

Query: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207
            TIE+L+ KI+    EN++ + QIDN +L ADD R KYE E++LRQ VE+D NGL+++L+
Sbjct: 169 KTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLD 228

Query: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267
            LTL + DLE Q++ LKEEL  L+ NH+EE+ +L+ Q G  +++E+ AAP  DL+++L E
Sbjct: 229 ELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNE 288

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           MR QYE + E NR+D E WF ++ EELN++V ++S+  Q  + E+ ELRR +  LE+ELQ
Sbjct: 289 MRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQ 348

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +Q  M+ S E  L ET+ RY   L+QIQ LI ++E QLA++RC +E+Q+QEY+ILLDVK+
Sbjct: 349 SQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKT 408

Query: 388 RLECEITTYRSLLESSDGKRPCYPRATKCEPS--PWTSCKSGAIESTAPACTSSSPCSLK 445
           RLE EI TYR LLE  D        + +   S   +TS  S +   T P     S  S  
Sbjct: 409 RLEQEIATYRRLLEGEDAHLSSQQASGQSYSSREVFTSSSSSSSRQTRPILKEQSSSSFS 468

Query: 446 E 446
           +
Sbjct: 469 Q 469


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  310 bits (794), Expect = 2e-84
 Identities = 163/317 (51%), Positives = 222/317 (70%), Gaps = 1/317 (0%)

Query: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP-DYLSYYTTI 150
           +  NEK TMQ LN+RLA+YL+KVR LE  NA+LE KI++   K+ P     DY  YY TI
Sbjct: 100 LTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTI 159

Query: 151 EELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLT 210
           EEL+ KIL    EN+R++ +IDN +L ADD R KYE E++LRQ VE+D NGL+++L+ LT
Sbjct: 160 EELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELT 219

Query: 211 LGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRC 270
           L K DLE Q++SL EEL  +K NH+EE+     Q+  ++++E+ A P  DL +VL EMR 
Sbjct: 220 LSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMRE 279

Query: 271 QYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQH 330
           QYE + E NR+D E+WF+ +  ELN++V T++   Q  + EI ELRR++  LE+ELQ+Q 
Sbjct: 280 QYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQL 339

Query: 331 RMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLE 390
            M+   E  + ETE RY   L QIQ LI ++EAQL+E+R  +E QNQEY++LLD+K+RLE
Sbjct: 340 SMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLE 399

Query: 391 CEITTYRSLLESSDGKR 407
            EI TYRSLLE  D K+
Sbjct: 400 QEIATYRSLLEGQDAKK 416


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  289 bits (739), Expect = 5e-78
 Identities = 162/321 (50%), Positives = 213/321 (66%), Gaps = 11/321 (3%)

Query: 89  GEG--INSNEKETMQILNERLANYLQKVRMLERENAELESKIQE------ESNKELPVLC 140
           G+G  ++ NEK TMQ LN+RLA+YL KVR LE  N ELE KI+E       S++  P   
Sbjct: 137 GDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEP--- 193

Query: 141 PDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDAN 200
            DY  YY TI++L+ +IL    +N+ ++ QIDN +L ADD R KYE EV+LRQ VE+D N
Sbjct: 194 RDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADIN 253

Query: 201 GLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSAD 260
           GL+++L+ LTL KADLE Q++SL EEL  LK NH+EE+  L+      +++E+ AAP  D
Sbjct: 254 GLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVD 313

Query: 261 LNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVN 320
           L Q+L  MR QYE + E NRKD E WFN + +EL  ++  + +Q    + EI ELRR+V 
Sbjct: 314 LTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQ 373

Query: 321 TLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYE 380
            LE+ELQ+Q  ++ S E  L ETE RY   L+QIQ+ I  LE QL +IR   E QN EY+
Sbjct: 374 ALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQ 433

Query: 381 ILLDVKSRLECEITTYRSLLE 401
            LLD+K RLE EI TYRSLLE
Sbjct: 434 QLLDIKIRLENEIQTYRSLLE 454


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  283 bits (723), Expect = 3e-76
 Identities = 163/389 (41%), Positives = 235/389 (60%), Gaps = 28/389 (7%)

Query: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQE----ESNKELPVLCPDYLSYY 147
           ++ +EKETMQ LN+RLA+YL KVR LE  N ELE+KI+E               DY  YY
Sbjct: 121 LSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYY 180

Query: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207
             IE+L+ KI+     N++L+ QIDN +L A+D R KYE E++LRQ VE+D NGL+++L+
Sbjct: 181 PLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLD 240

Query: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267
            LTL + DLE Q++SL EEL  +K NH++E+ S +      + +E+ AAP  DL ++L +
Sbjct: 241 ELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLND 300

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           MR QYE I E NRKD E WF  +  EL +++ T+++Q Q  + E+ +LRR+   LE+ELQ
Sbjct: 301 MRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQ 360

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +Q  M+ S E  L E E  Y A L+Q+Q LI NLEAQL ++R   ERQN +++ LL+VK+
Sbjct: 361 SQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKA 420

Query: 388 RLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEH 447
           RLE EI TYR LL+          +    E S + +      +ST    +S  P   +  
Sbjct: 421 RLELEIETYRRLLDGE-------AQGDGLEESLFVTDSKSQAQSTD---SSKDPTKTR-- 468

Query: 448 CSACGPLSRILVKICTITKEIKDGKVISS 476
                       KI T+ +E+ +G+V+SS
Sbjct: 469 ------------KIKTVVQEMVNGEVVSS 485


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  276 bits (706), Expect = 3e-74
 Identities = 147/318 (46%), Positives = 204/318 (64%), Gaps = 4/318 (1%)

Query: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147
           ++ NEK TMQ LN+RLA+YL+ VR LE  NA+LE KI+    K  P  C     DY  Y+
Sbjct: 80  LSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYF 139

Query: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207
             I+EL+ +I+     N+ +V Q DN +LTADD R K+E E++L Q VE+D NGL+++L+
Sbjct: 140 PIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLD 199

Query: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267
            LTL + DLE Q+++L EEL  LK NH+EE+ +LQC  G  +++E+ AAP  DL  +L  
Sbjct: 200 ELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNN 259

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           MR +YE + E NR+D E WFN +   L QQ+   +      + E+IE++R++ TLE+ELQ
Sbjct: 260 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQ 319

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +    + S EC LTETE+ Y A L QIQ+ I  LE QL ++R   E Q  EYE LLD+K 
Sbjct: 320 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKV 379

Query: 388 RLECEITTYRSLLESSDG 405
            LE EI TY  L++  DG
Sbjct: 380 HLEKEIETYCLLIDGEDG 397


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  274 bits (701), Expect = 1e-73
 Identities = 162/395 (41%), Positives = 234/395 (59%), Gaps = 18/395 (4%)

Query: 89  GEG--INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----- 141
           G+G   +  EK+TMQ LN+RLANYL KVR LE  N +LE+KI+E  +K  P         
Sbjct: 131 GDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGR 190

Query: 142 DYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANG 201
           DY  YY+ IE+L+ +I+    EN+ ++  IDN +L ADD R KYE E+ LRQ VE+D NG
Sbjct: 191 DYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADING 250

Query: 202 LKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADL 261
           L+++L+ LT+ ++DLE Q++S  EEL  L+ NH+EE+ ++Q   G  + +E+ AAP  DL
Sbjct: 251 LRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDL 310

Query: 262 NQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNT 321
            ++L +MR QYE + E NR++ E+ FN Q   L  Q+ T +      + EI EL+R++  
Sbjct: 311 TKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQA 370

Query: 322 LEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEI 381
           LE+ELQ+Q  M+ S E  L +TEA Y A L++IQ+ I  LE ++ +I    + QN EY+ 
Sbjct: 371 LEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQ 430

Query: 382 LLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSP 441
           LLD+K+RLE EI TYR LL+   G             + +    SG++   +    S   
Sbjct: 431 LLDIKTRLEVEIETYRRLLDGEGGGSSF---------AEFGGRNSGSVNMGSRDLVSGD- 480

Query: 442 CSLKEHCSACGPLSRILVKICTITKEIKDGKVISS 476
            S    CS  G  S       TI +E+ DGKV+SS
Sbjct: 481 -SRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSS 514


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  273 bits (699), Expect = 2e-73
 Identities = 159/393 (40%), Positives = 232/393 (59%), Gaps = 35/393 (8%)

Query: 84  DCSWYGEGINSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDY 143
           D +  G+    NEK  MQ LN+RLA+YL+KVR LE+ N++LE +I++      P    DY
Sbjct: 58  DLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDY 117

Query: 144 LSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLK 203
            +YY  IEEL+ +I   + +N+R V QIDN KL A+D R KYE E  +R  VE+D  GL 
Sbjct: 118 SAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLN 177

Query: 204 QILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQ 263
           ++ + LTL K DLE Q++ L ++L  LK  H+EE++ L   LG  +++EV AAP  +L  
Sbjct: 178 KVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGV 237

Query: 264 VLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLE 323
           ++ EMR +YE + + N ++ ++ F  Q   L QQV  ++++ +  + ++ ELRR+  +LE
Sbjct: 238 IMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLE 297

Query: 324 VELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILL 383
           +ELQ+   M++S E  L ET+ARY++ L  +QSL+ +LEAQL +IR  +ERQN EY ILL
Sbjct: 298 IELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILL 357

Query: 384 DVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCS 443
           D+K+RLE EI TYR LLE  D K   Y  +T  E           I+ T           
Sbjct: 358 DIKTRLEQEIATYRRLLEGEDVKTTEYQLSTLEERD---------IKKTR---------- 398

Query: 444 LKEHCSACGPLSRILVKICTITKEIKDGKVISS 476
                           KI T+ +E+ DGKV+SS
Sbjct: 399 ----------------KIKTVVQEVVDGKVVSS 415


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  271 bits (694), Expect = 8e-73
 Identities = 147/314 (46%), Positives = 199/314 (63%), Gaps = 4/314 (1%)

Query: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147
           ++ NEK TMQ LN+RLA+YL  VR LE  NAELE KI+    K  P  C     DY  Y+
Sbjct: 82  LSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYH 141

Query: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207
            TIE+L+ KI+ +   N+ ++ QIDN +L ADD R KYE E++L Q VE+D NGL+++L+
Sbjct: 142 LTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLD 201

Query: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267
            LTL + D E Q +SL EE+  LK NH+EE+ +LQC  G  +++E+ AAP  DL  +L  
Sbjct: 202 ELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNN 261

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           MR +YE + E NRKD E WFN +   L QQ+   S      + ++ E+RR++ TLE++LQ
Sbjct: 262 MRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQ 321

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +    + S EC LTETE+ Y   L QIQ+ I  LE QL ++R   E Q  EYE LLDVK 
Sbjct: 322 SLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKV 381

Query: 388 RLECEITTYRSLLE 401
            LE EI TY  L++
Sbjct: 382 HLEKEIETYCRLID 395


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  271 bits (692), Expect = 1e-72
 Identities = 150/344 (43%), Positives = 205/344 (59%), Gaps = 21/344 (6%)

Query: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147
           ++ NEK TMQ LN+RLA+YL  V  LE  NA+LE KI+    K  P  C     DY  Y+
Sbjct: 75  LSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYF 134

Query: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207
             I++L+ +I+ +   N+  V QIDN +LTADD R KYE E++L Q VE+D NGL+++L+
Sbjct: 135 PIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLD 194

Query: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267
            +TL + DLE Q ++L EE+  LK NHKEE+  LQC  G  +++E+ AAP  DL  +L  
Sbjct: 195 EITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNN 254

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           MR +YE + E NR+D E WFN +   L QQ+          + E+ E++R++ TLE+ELQ
Sbjct: 255 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQ 314

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +    + S EC LTETE+ Y A L QIQ+ I  LE QL ++R   E Q  EYE LLD+K 
Sbjct: 315 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKL 374

Query: 388 RLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIES 431
            LE EI TY  L+   DG                 +CKSG  +S
Sbjct: 375 HLEKEIETYCLLIGGDDG-----------------ACKSGGYKS 401


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  270 bits (691), Expect = 2e-72
 Identities = 143/316 (45%), Positives = 211/316 (66%), Gaps = 3/316 (0%)

Query: 89  GEG--INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPV-LCPDYLS 145
           G+G  + +NEK TMQ LN RLA+YL KV+ LE  N +LE+KIQ+  +K+ P  +  +Y  
Sbjct: 144 GDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSP 203

Query: 146 YYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQI 205
           YY TI++L+ +I+     N++ +  IDNT++T DD R K+E E +LRQ V++D NGL+Q+
Sbjct: 204 YYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQV 263

Query: 206 LNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVL 265
           L+ LT+ K+DLE Q ++L+EEL+ LK NHKEE++ L  Q    +++E+  AP  DL + L
Sbjct: 264 LDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTL 323

Query: 266 QEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVE 325
            +MR +YE ++  NRKD+E  + TQI ++  +V +S Q+ Q   KE+ +LR  V  LE+E
Sbjct: 324 NDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIE 383

Query: 326 LQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDV 385
           LQ+Q   + + E  L +T+ RY   L  IQ  I NLEAQ+ ++R  +E QNQEY +LL +
Sbjct: 384 LQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSI 443

Query: 386 KSRLECEITTYRSLLE 401
           K RLE EI TY +LLE
Sbjct: 444 KMRLEKEIETYHNLLE 459


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  261 bits (666), Expect = 1e-69
 Identities = 135/317 (42%), Positives = 209/317 (65%), Gaps = 2/317 (0%)

Query: 89  GEGINSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYT 148
           G G   NEKETMQ LN+RLA+YL +VR LE EN  LESKI+E   K+ P +  D+  Y+ 
Sbjct: 73  GMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFK 131

Query: 149 TIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNV 208
            IE+L+ +I     +N+R+V QIDN +L ADD R KYE E+++RQ VE+D +GL+++++ 
Sbjct: 132 IIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDD 191

Query: 209 LTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGER-LDIEVTAAPSADLNQVLQE 267
             + +  LE ++++LKEELL +K NH+EE+  LQ Q+    L +EV A  S DL +++ +
Sbjct: 192 TNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMAD 251

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           +R QY+ +   NR++++++++ QIEE    V T S +    +  + ELRR+V +LE++L 
Sbjct: 252 IRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLD 311

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +   ++ S E  L E EARY   + Q+  ++ +LE++LA+ R   +RQ QEYE LL++K 
Sbjct: 312 SMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKV 371

Query: 388 RLECEITTYRSLLESSD 404
           +LE EI TYR LLE  +
Sbjct: 372 KLEAEIATYRRLLEDGE 388


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  261 bits (666), Expect = 1e-69
 Identities = 135/317 (42%), Positives = 209/317 (65%), Gaps = 2/317 (0%)

Query: 89  GEGINSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYT 148
           G G   NEKETMQ LN+RLA+YL +VR LE EN  LESKI+E   K+ P +  D+  Y+ 
Sbjct: 73  GMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFK 131

Query: 149 TIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNV 208
            IE+L+ +I     +N+R+V QIDN +L ADD R KYE E+++RQ VE+D +GL+++++ 
Sbjct: 132 IIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDD 191

Query: 209 LTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGER-LDIEVTAAPSADLNQVLQE 267
             + +  LE ++++LKEELL +K NH+EE+  LQ Q+    L +EV A  S DL +++ +
Sbjct: 192 TNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMAD 251

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           +R QY+ +   NR++++++++ QIEE    V T S +    +  + ELRR+V +LE++L 
Sbjct: 252 IRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLD 311

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +   ++ S E  L E EARY   + Q+  ++ +LE++LA+ R   +RQ QEYE LL++K 
Sbjct: 312 SMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKV 371

Query: 388 RLECEITTYRSLLESSD 404
           +LE EI TYR LLE  +
Sbjct: 372 KLEAEIATYRRLLEDGE 388


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  248 bits (634), Expect = 7e-66
 Identities = 142/325 (43%), Positives = 193/325 (59%), Gaps = 6/325 (1%)

Query: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147
           ++ NEK TMQ LN+RLA+YL  V  LE  NA+LE KI+    K  P        DY  Y+
Sbjct: 79  LSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYF 138

Query: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207
           + IE+L+++I      N+ +V Q DN +LTADD R KYE E++L   VE+D +GL+++L+
Sbjct: 139 SVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLD 198

Query: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267
            LTL   DLE Q ++L EEL  LK +H+EE+  LQ   G  +++E+ A P  DL  +L  
Sbjct: 199 ELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNN 258

Query: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
           MR +YE + E NRKD E WFN +   L QQ+          + E+ EL+R++ TLE+ELQ
Sbjct: 259 MRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQ 318

Query: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
           +   ++ S EC L ETE  Y   L QIQ  I  +E QL +IR   E Q  EYE LLDVK 
Sbjct: 319 SLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKI 378

Query: 388 RLECEITTYRSLLESSD--GKRPCY 410
            LE EI  Y +LL+  +   K  CY
Sbjct: 379 FLEKEIDIYCNLLDGEERKSKSTCY 403


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  225 bits (573), Expect = 8e-59
 Identities = 122/330 (36%), Positives = 201/330 (60%), Gaps = 2/330 (0%)

Query: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIE 151
           +  N K TMQ LN+RLA+YL+KVR LE  N +LES+I +   +  P    DY  Y   I 
Sbjct: 68  LGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENIT 127

Query: 152 ELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTL 211
            LQ++I+  K  N++++  IDN ++  DD   KYE E S ++ +E +  GL++ L+ LT+
Sbjct: 128 HLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTI 187

Query: 212 GKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQ 271
              DLE +V+ +++EL+ +K +H++E+          ++++V   P  DL +VL++MR +
Sbjct: 188 VTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQE 247

Query: 272 YEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHR 331
           YE I++   +D++ W+  Q   ++Q+   S    Q  Q +I EL+R+   LE++LQ Q+ 
Sbjct: 248 YELIIKKKHRDLDTWYKEQSAAMSQE-AASPATVQSRQGDIHELKRTFQALEIDLQTQYS 306

Query: 332 MRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLEC 391
            + + E +L+ET++RY+  L  +Q +I + E +L ++R  LERQN EY++LL +K+ LE 
Sbjct: 307 TKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEK 366

Query: 392 EITTYRSLLE-SSDGKRPCYPRATKCEPSP 420
           EITTYR LLE  S+G R     + K   +P
Sbjct: 367 EITTYRRLLEGESEGTREESKSSMKVSATP 396


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,426,475
Number of Sequences: 37866
Number of extensions: 853577
Number of successful extensions: 5797
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 183
Number of HSP's successfully gapped in prelim test: 493
Number of HSP's that attempted gapping in prelim test: 3980
Number of HSP's gapped (non-prelim): 1689
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.