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Search of human proteins with 147903302
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|147903302 MAP7 domain containing 3 [Homo sapiens]
(876 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|147903302 MAP7 domain containing 3 [Homo sapiens] 1700 0.0
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 176 6e-44
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 150 6e-36
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 107 4e-23
gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens] 82 2e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 68 4e-11
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 67 6e-11
gi|110349719 titin isoform N2-A [Homo sapiens] 67 9e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 65 3e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 65 3e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 65 3e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 65 3e-10
gi|116284392 mucin 2 precursor [Homo sapiens] 64 5e-10
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 63 1e-09
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 60 7e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 59 2e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 59 3e-08
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 58 3e-08
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 58 4e-08
gi|148746195 trichohyalin [Homo sapiens] 57 6e-08
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 57 7e-08
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 57 7e-08
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 57 1e-07
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 57 1e-07
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 56 1e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 56 1e-07
gi|21389509 KPL2 protein isoform 2 [Homo sapiens] 56 2e-07
gi|145699133 KPL2 protein isoform 1 [Homo sapiens] 56 2e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 54 5e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 54 6e-07
>gi|147903302 MAP7 domain containing 3 [Homo sapiens]
Length = 876
Score = 1700 bits (4402), Expect = 0.0
Identities = 876/876 (100%), Positives = 876/876 (100%)
Query: 1 MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDG 60
MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDG
Sbjct: 1 MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDG 60
Query: 61 SMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKE 120
SMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKE
Sbjct: 61 SMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKE 120
Query: 121 EQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTAN 180
EQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTAN
Sbjct: 121 EQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTAN 180
Query: 181 KRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQA 240
KRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQA
Sbjct: 181 KRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQA 240
Query: 241 ERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPK 300
ERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPK
Sbjct: 241 ERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPK 300
Query: 301 ASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDA 360
ASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDA
Sbjct: 301 ASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDA 360
Query: 361 SPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKG 420
SPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKG
Sbjct: 361 SPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKG 420
Query: 421 SAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQAL 480
SAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQAL
Sbjct: 421 SAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQAL 480
Query: 481 IPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPY 540
IPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPY
Sbjct: 481 IPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPY 540
Query: 541 KIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAAT 600
KIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAAT
Sbjct: 541 KIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAAT 600
Query: 601 KILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNE 660
KILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNE
Sbjct: 601 KILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNE 660
Query: 661 TKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMK 720
TKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMK
Sbjct: 661 TKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMK 720
Query: 721 RTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNN 780
RTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNN
Sbjct: 721 RTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNN 780
Query: 781 AKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTT 840
AKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTT
Sbjct: 781 AKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTT 840
Query: 841 KTRKADETNTTSRSSAQTKSEGFHDILPKSSDTFRQ 876
KTRKADETNTTSRSSAQTKSEGFHDILPKSSDTFRQ
Sbjct: 841 KTRKADETNTTSRSSAQTKSEGFHDILPKSSDTFRQ 876
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 176 bits (447), Expect = 6e-44
Identities = 199/718 (27%), Positives = 316/718 (44%), Gaps = 114/718 (15%)
Query: 42 RVATHSSNIRSTFKPVIDGSMLKNDIKQ-----RLARERREEKRRQQDANKETQLLEKER 96
R SS T P D K ++K+ +LA+ERREE+ + A K L EKE
Sbjct: 107 RPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWL-EKEE 165
Query: 97 KTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLA 156
K K EKQ++ER+R+L+E++ K EQRR A EE++ QK E KE++ A + R++++
Sbjct: 166 KAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWA- 224
Query: 157 DDYQQKRWSWGGSAMANSES-KTANKR-SASTEKLEQGTSALI-RQMPLSSAGLQNSVAK 213
+ +Q+RWSW G+ +S KT+ R S S L + ++I +++ SSA L NS ++
Sbjct: 225 -EIRQQRWSWAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSR 283
Query: 214 RKTDKERSSSLNRRDSN----LHSSTDKEQAERKPRVTGVTNYVMQYVTV-PLRKCTSDE 268
RS L+ +S+ L + T A + VT N Q P R T
Sbjct: 284 N-----RSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGR 338
Query: 269 LRAVM---------FPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSM 319
A + P + + + P++ SPL AP E
Sbjct: 339 AGASLARGPQPDRTHPSAAVPVCPRS-ASASPLTPCSVTRSVHRCAPAGERGE------- 390
Query: 320 EASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPK 379
P AG AP + SPV + + E S A + +
Sbjct: 391 RRKPNAGGSPAPVRRRP-------EASPVQKKEKKDKERENEKEKSALARER---SLKKR 440
Query: 380 VSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESME 439
S+ ASP A L A L + ++P S P P ++ P
Sbjct: 441 QSLPASPRARLSASTASELSPKSKAR-PSSPSTSWHRPASPCPSPGPGHTLPPKPP---- 495
Query: 440 ASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSS 499
SP ASPK + EA A KS+ +K+R S+ E S+
Sbjct: 496 -SPRGTT-ASPKGRVRRKEEAKESPSAAGPEDKSQ---------SKRRASNEKE----SA 540
Query: 500 SPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVK 559
+P + P+P T QK PP+ P + + TS P P+
Sbjct: 541 APASPAPSPAPSPTPAPPQKEQPPAETP--TDAAVLTSPPAPAPPV-------------- 584
Query: 560 KKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEE 619
+ +K AG + E AT++L E RR AREQRE+EE+
Sbjct: 585 -------------------------TPSKPMAGTTDREEATRLLAEKRRQAREQREREEQ 619
Query: 620 ERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEA-PLQ 678
ER+ + + + +++ + +A+EA +A + + +++ + ++K +QE+QE Q
Sbjct: 620 ERRLQAERDKRMREEQ-LAREA---EARAEREAEARRREEQEAREKAQAEQEEQERLQKQ 675
Query: 679 KGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETS 736
K +A+ +++EEA++++ E E+ Q QER ER+KR+EEIMKRTRK++V+ +K + S
Sbjct: 676 KEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDS 733
Score = 50.8 bits (120), Expect = 5e-06
Identities = 47/199 (23%), Positives = 88/199 (44%), Gaps = 30/199 (15%)
Query: 17 RELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERR 76
RE R++A A+E+R+++ R + R + L + + R RE
Sbjct: 596 REEATRLLAEKRRQAREQREREEQERRLQAERDKR------MREEQLAREAEARAEREAE 649
Query: 77 EEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDE 136
+R +Q+A ++ Q E+E + +LQ KQ EE + + +E E++ R EK Q+ E
Sbjct: 650 ARRREEQEAREKAQA-EQEEQERLQ--KQKEEAEARSREEAERQRLER----EKHFQQQE 702
Query: 137 AQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSAL 196
++++ R+RL + ++ R S +SK AN +S E
Sbjct: 703 QERQE---------RRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEP-------- 745
Query: 197 IRQMPLSSAGLQNSVAKRK 215
++ + S GLQ +++
Sbjct: 746 VKAVEARSPGLQKEAVQKE 764
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/262 (24%), Positives = 100/262 (38%), Gaps = 60/262 (22%)
Query: 387 EASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMV 446
E APP V PE +PEG PP + + P ++ +P AM
Sbjct: 8 ELGAGAPPAVVARTPPEP--RPSPEGDPSPPPPPMSALVP---------DTPPDTPPAMK 56
Query: 447 KASPKTSLEASMEA-SPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENAC 505
A+ L E+ S + R AP + E S S E
Sbjct: 57 NATSSKQLPLEPESPSGQVGPRPAPPQEE-----------------------SPSSEAKS 93
Query: 506 GLPSPISTN----RQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKK 561
P+P + R +++ PSP + + SP T K +H L+ K++
Sbjct: 94 RGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLA--------KER 145
Query: 562 KETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEER 621
+E R + L+ + ++ E K+ A K L E RR EQR K E+ R
Sbjct: 146 RE------ERAKYLAAKKAVWLEKEEKAKA------LREKQLQERRRRLEEQRLKAEQRR 193
Query: 622 QR-EEMQQRVIKKSKDMAKEAV 642
EE Q++ ++K+K+ + A+
Sbjct: 194 AALEERQRQKLEKNKERYEAAI 215
Score = 37.0 bits (84), Expect = 0.080
Identities = 33/153 (21%), Positives = 67/153 (43%), Gaps = 15/153 (9%)
Query: 93 EKERKTKLQYEKQMEERQRKLKERKEKEEQ-RRIAAEEKRHQKDEAQKEKFTAILYRTLE 151
++E T+L + E++R+ +E++E+EEQ RR+ AE + ++E + A R E
Sbjct: 595 DREEATRL-----LAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAE 649
Query: 152 RRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLE-QGTSALIRQMPLSSAGLQNS 210
RR + +++ A +E + + E+ E + RQ Q
Sbjct: 650 ARRREEQEAREK--------AQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQ 701
Query: 211 VAKRKTDKERSSSLNRRDSNLHSSTDKEQAERK 243
+R+ ++R + +R S K++ + K
Sbjct: 702 EQERQERRKRLEEIMKRTRKSEVSETKQKQDSK 734
Score = 36.2 bits (82), Expect = 0.14
Identities = 19/77 (24%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 68 KQRLARER---REEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRR 124
+QRL RE+ ++E+ RQ+ + +++++ RK+++ KQ ++ + E +
Sbjct: 689 RQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKA 748
Query: 125 IAAEEKRHQKDEAQKEK 141
+ A QK+ QKE+
Sbjct: 749 VEARSPGLQKEAVQKEE 765
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 150 bits (378), Expect = 6e-36
Identities = 207/863 (23%), Positives = 348/863 (40%), Gaps = 166/863 (19%)
Query: 6 AAAGAGGSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSS---NIRSTFKPVIDGSM 62
A GAGG A A + K + K++ +R A+ S N S KP +
Sbjct: 2 AELGAGGDGHRGGDGAVRSETAPDSYKVQDKKNASSRPASAISGQNNNHSGNKPD-PPPV 60
Query: 63 LKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQ 122
L+ D +QRLARERREE+ +Q A +E LE+E + + YEK +EER+++L+E+++KEE+
Sbjct: 61 LRVDDRQRLARERREEREKQLAA-REIVWLEREERARQHYEKHLEERKKRLEEQRQKEER 119
Query: 123 RRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTA--N 180
RR A EEKR Q+ E KE+ A++ RT+ER + + RWSWGGS + +A +
Sbjct: 120 RRAAVEEKRRQRLEEDKERHEAVVRRTMERSQ-KPKQKHNRWSWGGSLHGSPSIHSADPD 178
Query: 181 KRSASTEKLEQGTSALI-RQMPLSSAGLQNS---VAKRKTDKERSSSLNRRDSNLHS--S 234
+RS ST L + +I +++ SSA L NS + + SS +NR + HS +
Sbjct: 179 RRSVSTMNLSKYVDPVISKRLSSSSATLLNSPDRARRLQLSPWESSVVNRLLTPTHSFLA 238
Query: 235 TDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEK 294
K A + +M Y R ++M P +
Sbjct: 239 RSKSTAALSGEAASCSPIIMPYKAAHSR--------------NSMDRP----------KL 274
Query: 295 VETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDS 354
TPP+ S S E ++ ++ VS +
Sbjct: 275 FVTPPEGS---------------SRRRIIHGTASYKKERERENVLFLTSGTRRAVSPSNP 319
Query: 355 EMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEV---SLEALPEVSVEAAPE 411
+ A L + + L P+ + P + AP +V S + V E E
Sbjct: 320 KARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGSVKAAPAQVRPPSPGNIRPVKREVKVE 379
Query: 412 GSLEAPPKGSAEVAPKESVKGSPK--ESMEASPEAMVKASPKTSLEASMEASPKAKARDA 469
+ P K +VA + S+KG + EA+ E A P+ A A A A
Sbjct: 380 PEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPA---SA 436
Query: 470 PKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLI 529
P + A +P +S+ + S+S + + G P R
Sbjct: 437 PAPASAPAPAPVP-TPAMVSAPSSTVNASASVKTSAGTTDPEEATR-------------- 481
Query: 530 SKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKS 589
++ + L+ + ++++E + E L+QR
Sbjct: 482 ------------LLAEKRRLAREQREKEERERREQEELERQKREELAQR----------- 518
Query: 590 TAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDH 649
+ E T+ E RRL EQ ++EE+ QR QAE+
Sbjct: 519 ----VAEERTTRREEESRRLEAEQAREKEEQLQR---------------------QAEER 553
Query: 650 LKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERL 709
L++ ++ +++K ++EA +++ +++ + E +++E QERL
Sbjct: 554 -ALREREEAERAQRQK------EEEARVREEAERVRQEREKHFQREE---------QERL 597
Query: 710 ERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTG 769
ERKKR+EEIMKRTR+T+ K ++ + DI + A E SA+ T
Sbjct: 598 ERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTE----------VSALPCTTN 647
Query: 770 SPTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSR 829
+P K + +H+ + T + K+P N S+++ + +E+++
Sbjct: 648 APGNGKPVGSPHVVTSHQSKVTVESTPDLEKQP---------NENGVSVQNENFEEIINL 698
Query: 830 PSSKRMTSHTTKTRKADETNTTS 852
P +K + D TN+ S
Sbjct: 699 PIG-------SKPSRLDVTNSES 714
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 107 bits (268), Expect = 4e-23
Identities = 73/194 (37%), Positives = 111/194 (57%), Gaps = 18/194 (9%)
Query: 1 MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDG 60
M G +G G P E AR + +IA+ V T N ++P
Sbjct: 1 MERGGGGSGTGSRP---EGTARGTSLPGKIAEP-------GAVRTSQPN----YRPQGME 46
Query: 61 SMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKE 120
LK+D +QRLA+ERREE+ + A +E Q+LEK+++ +LQYEKQMEER RKL+E++++E
Sbjct: 47 GFLKSDERQRLAKERREEREKCLAA-REQQILEKQKRARLQYEKQMEERWRKLEEQRQRE 105
Query: 121 EQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGS-AMANSESKTA 179
+Q+R A EEKR QK ++E+ A++ R+LER + + +K++SWG A+
Sbjct: 106 DQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLE--LKKKYSWGAPLAIGPGGHDAC 163
Query: 180 NKRSASTEKLEQGT 193
+K S ST L + T
Sbjct: 164 DKLSTSTMSLPKPT 177
Score = 102 bits (253), Expect = 2e-21
Identities = 88/266 (33%), Positives = 128/266 (48%), Gaps = 65/266 (24%)
Query: 527 PLISK-------QSPQTSFP-YKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQ- 577
P+ISK QSP+T+ P Y P+++ L S K+K E R L+Q
Sbjct: 291 PVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQ 350
Query: 578 -----------RHMIYEESGNKS-----------------TAGIMNAEAATKILTELRRL 609
+H++ + + K TAG +A A KIL E RR
Sbjct: 351 AAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQ 410
Query: 610 AREQREKEEEERQREEMQQRVIKKS--KDMAKEAVGGQAEDHLKLKDGQQQNETKKK--- 664
AR Q+E+EE+ER +E Q R+ ++ + +E + + E + ++ ++Q E KKK
Sbjct: 411 ARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEG 470
Query: 665 --------------------KGWLDQEDQEAPL---QKGDAKIKAQEEADKRKKEHERIM 701
K +QE QE + QK A+ KA+E A++ + E E+IM
Sbjct: 471 EEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIM 530
Query: 702 LQNLQERLERKKRIEEIMKRTRKTDV 727
LQ QERLERKKRI+EIMKRTRK+DV
Sbjct: 531 LQIEQERLERKKRIDEIMKRTRKSDV 556
Score = 49.3 bits (116), Expect = 2e-05
Identities = 76/317 (23%), Positives = 130/317 (41%), Gaps = 65/317 (20%)
Query: 78 EKRRQ---QDANKETQLLEKERKTKLQYE----KQMEERQRKLKERKEKEEQRRIAAEEK 130
EKRRQ Q +E + +EKE + +L+ E K EER R +E +++EE+R+ EEK
Sbjct: 406 EKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEK 465
Query: 131 RHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLE 190
+ Q+ E E+R+ ++ ++K +E + K EK E
Sbjct: 466 KKQEGE--------------EKRKAGEEAKRK-----------AEEELLLKEKQEQEKQE 500
Query: 191 QGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVT 250
+ A+I + Q A+ K +E + + + ++E+ ERK R+ +
Sbjct: 501 K---AMIEK--------QKEAAETKA-REVAEQMRLEREQIMLQIEQERLERKKRIDEIM 548
Query: 251 NYVMQYVTVPLRKCTSDEL---RAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPP 307
+ P K ++ AV T + P K+E + L + AP
Sbjct: 549 KRTRKSDVPPQVKKEDPKVGVQPAVCVEKKTKLVVP-NKMEINGLNTCQEVNGVDHAAPE 607
Query: 308 QVNVEVFCNTSMEASPKAGV-------GMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDA 360
++F N P G+ G + + + V S+DVSPV S+ + +
Sbjct: 608 TYPQDIFSN---GLKPAGGLIHLDALDGKSNSLDDSTEEVQSMDVSPV-----SKEELIS 659
Query: 361 SPELS--IEALPKVDLE 375
PE S E +P V L+
Sbjct: 660 IPEFSPVSEMIPGVSLD 676
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 7 AAGAGGSPSLRELRARMVAA---ANEIAK---ERRKQDVVNRVATHSSNIRSTFKPVIDG 60
AA AGG + A A E AK E+R+Q + + + + ++
Sbjct: 374 AAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLER 433
Query: 61 SMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKER---K 117
LK ++ R R EE+ R+Q+ ++ Q EK+++ + K EE +RK +E K
Sbjct: 434 EELKRKAEEE--RLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLK 491
Query: 118 EKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
EK+EQ + QK+ A+ + LER ++ +Q+R
Sbjct: 492 EKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQER 537
Score = 35.4 bits (80), Expect = 0.23
Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 24/113 (21%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E +RLA+E+R EE E+ +Q++++K K + Q E + +
Sbjct: 53 ERQRLAKERR--EEREKCLAAREQQILEKQ------------------KRARLQYEKQME 92
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQER-LERKKRIE 716
+ W E+Q Q+ D K A EE K+K E L+ + R LER +++E
Sbjct: 93 ERWRKLEEQR---QREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLE 142
Score = 30.0 bits (66), Expect = 9.8
Identities = 24/101 (23%), Positives = 49/101 (48%), Gaps = 17/101 (16%)
Query: 623 REEMQQRVIKKSKDMAKEAVGGQAEDHL-KLKDGQQQNETKKKKGWLDQEDQEAPLQKGD 681
+ + +QR+ K+ ++ ++ + + + L K K + Q E + ++ W E+Q Q+ D
Sbjct: 50 KSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQR---QRED 106
Query: 682 AKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRT 722
K A EE K+K E ++R+E +M+R+
Sbjct: 107 QKRAAVEEKRKQKLREE-------------EERLEAMMRRS 134
Score = 30.0 bits (66), Expect = 9.8
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 9/74 (12%)
Query: 603 LTELRRLAREQREKEEEERQR--EEMQQRVIKKSKDMAKEAVGGQAEDHLKLK------- 653
+ E ++ AR Q EK+ EER R EE +QR +K + ++ E+ +L+
Sbjct: 76 ILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSL 135
Query: 654 DGQQQNETKKKKGW 667
+ QQ E KKK W
Sbjct: 136 ERTQQLELKKKYSW 149
>gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens]
Length = 1180
Score = 82.4 bits (202), Expect = 2e-15
Identities = 60/220 (27%), Positives = 109/220 (49%), Gaps = 5/220 (2%)
Query: 259 VPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTS 318
V L + + E P + + P+ V SP V P+A+V P+ V +
Sbjct: 38 VSLYRRRAPEAAVFHSPEAAVYHSPEATVYHSPEAAVYHSPEAAVFHSPEAAVYHSPEAA 97
Query: 319 MEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETV 377
+ SP+A V +PE + P +V SP + + S E ++ SPE ++ P+ +
Sbjct: 98 VYHSPEAAVFHSPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYRSPEAAVFRSPEAAVYRS 157
Query: 378 PKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKES 437
P+ ++ SPEA++ PE ++ PE +V +PE ++ P+ + +P+ +V P+ +
Sbjct: 158 PEAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHSPEAAVFHCPEAA 217
Query: 438 MEASPEAMVKASPKTSL----EASMEASPKAKARDAPKKS 473
+ SPEA V SP+ ++ EA++ SP+A +P+ S
Sbjct: 218 VYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEAS 257
Score = 77.4 bits (189), Expect = 5e-14
Identities = 60/206 (29%), Positives = 99/206 (48%), Gaps = 5/206 (2%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P + + P+ V SP V P+A+V P+ V ++ SP+A
Sbjct: 69 SPEAAVYHSPEAAVFHSPEAAVYHSPEAAVYHSPEAAVFHSPEAAVYHSPEAAVFHSPEA 128
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVA 384
V +PE + P +V SP + Y S E ++ SPE ++ P+ + P+ ++
Sbjct: 129 AVFHSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEAAVYR 188
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
SPEA++ PE ++ PE +V PE ++ P+ + +P+ +V P+ ++ SPEA
Sbjct: 189 SPEAAVYRSPEAAVFHSPEAAVFHCPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEA 248
Query: 445 MVKASPKTSLEASMEASPKAKARDAP 470
V SP EAS+ SP A +P
Sbjct: 249 AVYHSP----EASVFHSPGAAVFHSP 270
Score = 73.9 bits (180), Expect = 6e-13
Identities = 59/206 (28%), Positives = 99/206 (48%), Gaps = 5/206 (2%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P + + P+ V SP V P+A+V P+ V ++ SP+A
Sbjct: 85 SPEAAVYHSPEAAVYHSPEAAVFHSPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYRSPEA 144
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVA 384
V +PE + P +V SP + Y S E ++ SPE ++ P+ + P+ ++
Sbjct: 145 AVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFH 204
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
SPEA++ PE ++ PE +V +PE ++ P+ + +P+ +V SP+ S+ SP A
Sbjct: 205 SPEAAVFHCPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGA 264
Query: 445 MVKASPKTSLEASMEASPKAKARDAP 470
V SP A++ SP A +P
Sbjct: 265 AVFHSP----GAAVYHSPGAAVYHSP 286
Score = 72.8 bits (177), Expect = 1e-12
Identities = 59/206 (28%), Positives = 97/206 (47%), Gaps = 5/206 (2%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P + + P+ V SP V P+A+V P+ V ++ SP+A
Sbjct: 101 SPEAAVFHSPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYRSPEAAVFRSPEAAVYRSPEA 160
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVA 384
V +PE + P +V SP + Y S E ++ SPE ++ P+ + P+ ++
Sbjct: 161 AVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHSPEAAVFHCPEAAVYR 220
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
SPEA++ PE ++ PE +V +PE ++ P+ S +P +V SP ++ SP A
Sbjct: 221 SPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGA 280
Query: 445 MVKASPKTSLEASMEASPKAKARDAP 470
V SP A++ SP A +P
Sbjct: 281 AVYHSP----GAAVYHSPGAAVYHSP 302
Score = 70.9 bits (172), Expect = 5e-12
Identities = 59/206 (28%), Positives = 96/206 (46%), Gaps = 5/206 (2%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P + + P+ V SP V P+A+V P+ V ++ SP+A
Sbjct: 109 SPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEA 168
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVA 384
V +PE + P +V SP + Y S E ++ SPE ++ P+ + P+ ++
Sbjct: 169 AVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHSPEAAVFHCPEAAVYRSPEAAVYR 228
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
SPEA++ PE ++ PE +V +PE S+ P + +P +V SP ++ SP A
Sbjct: 229 SPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGA 288
Query: 445 MVKASPKTSLEASMEASPKAKARDAP 470
V SP A++ SP A +P
Sbjct: 289 AVYHSP----GAAVYHSPGAAVYHSP 310
Score = 63.9 bits (154), Expect = 6e-10
Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 1/197 (0%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P + + P+ V SP V P+A+V P+ V ++ SP+A
Sbjct: 117 SPEAAVFHSPEAAVFHSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEA 176
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVA 384
V +PE + P +V SP + + S E ++ PE ++ P+ + P+ ++
Sbjct: 177 AVFRSPEAAVYRSPEAAVYRSPEAAVFHSPEAAVFHCPEAAVYRSPEAAVYRSPEAAVFH 236
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
PEA++ PE ++ PE SV +P ++ P + +P +V SP ++ SP A
Sbjct: 237 CPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVYHSPGA 296
Query: 445 MVKASPKTSLEASMEAS 461
V SP ++ S A+
Sbjct: 297 AVYHSPGAAVYHSPGAA 313
Score = 60.8 bits (146), Expect = 5e-09
Identities = 50/186 (26%), Positives = 84/186 (45%), Gaps = 1/186 (0%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P + + P+ V SP V P+A+V P+ V ++ SP+A
Sbjct: 133 SPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEA 192
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVA 384
V +PE + P +V P + Y S E ++ SPE ++ P+ + P+ ++
Sbjct: 193 AVYRSPEAAVFHSPEAAVFHCPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYH 252
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
SPEAS+ P ++ P +V +P ++ P + +P +V SP ++ SP A
Sbjct: 253 SPEASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPGA 312
Query: 445 MVKASP 450
V SP
Sbjct: 313 AVFHSP 318
Score = 55.8 bits (133), Expect = 2e-07
Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 5/189 (2%)
Query: 283 PQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVS 342
P V SP V P A+V P V ++ SP A V +P + P +
Sbjct: 294 PGAAVYHSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPGAA 353
Query: 343 VDVSPVVSTYDSE-MSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEAL 401
V SP + + S ++ SP ++ P+ + P+ ++ SPEA++ PE ++
Sbjct: 354 VYHSPGAAVFRSPGAAVFRSPGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHC 413
Query: 402 PEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEAS 461
PE +V +PE ++ P+ S +P +V SP ++ SP A V SP A++ S
Sbjct: 414 PEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSP----GAAVYHS 469
Query: 462 PKAKARDAP 470
P A +P
Sbjct: 470 PGAAVYHSP 478
Score = 55.5 bits (132), Expect = 2e-07
Identities = 54/193 (27%), Positives = 86/193 (44%), Gaps = 5/193 (2%)
Query: 283 PQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVS 342
P V SP V P A+V P V ++ SP A V +P + P +
Sbjct: 302 PGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAA 361
Query: 343 VDVSPVVSTYDSE-MSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEAL 401
V SP + + S ++ SPE ++ P+ + P+ ++ SPEA++ PE ++
Sbjct: 362 VFRSPGAAVFRSPGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHS 421
Query: 402 PEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEA- 460
PE +V +PE S+ P + +P +V SP ++ SP A V SP ++ S A
Sbjct: 422 PEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHSPGAA 481
Query: 461 ---SPKAKARDAP 470
SP A +P
Sbjct: 482 VFHSPGAAVYHSP 494
Score = 53.9 bits (128), Expect = 6e-07
Identities = 53/193 (27%), Positives = 85/193 (44%), Gaps = 5/193 (2%)
Query: 283 PQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVS 342
P V SP V P A+V P V ++ SP A V +P + P +
Sbjct: 318 PGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFRSPGAAVFRSPGAA 377
Query: 343 VDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEAL 401
V SP + + S E ++ SPE ++ P+ + P+ ++ SPEA++ PE S+
Sbjct: 378 VYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHS 437
Query: 402 PEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEA- 460
P +V +P ++ P + +P +V SP ++ SP A V SP ++ S A
Sbjct: 438 PGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVYHSPGAA 497
Query: 461 ---SPKAKARDAP 470
SP A +P
Sbjct: 498 VFHSPGAAVYHSP 510
Score = 52.0 bits (123), Expect = 2e-06
Identities = 49/197 (24%), Positives = 85/197 (43%), Gaps = 1/197 (0%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P + + P+ V SP V P+A+V P+ V S+ SP+A
Sbjct: 810 SREAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPEA 869
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDSE-MSMDASPELSIEALPKVDLETVPKVSIVA 384
V +PE + P +V SP + + S ++ SP ++ P + P ++
Sbjct: 870 AVYHSPEAAVFHSPGAAVFHSPGAAVFHSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYR 929
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
SP A++ P ++ P +V +P ++ P + +P +V SP ++ SP A
Sbjct: 930 SPGAAVYRSPGAAVFRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGA 989
Query: 445 MVKASPKTSLEASMEAS 461
V SP ++ S A+
Sbjct: 990 AVYRSPGAAVFRSPGAA 1006
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/180 (26%), Positives = 81/180 (45%), Gaps = 4/180 (2%)
Query: 283 PQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVS 342
P+ V SP V P A+V P V ++ S A V + + P +
Sbjct: 750 PEAAVYRSPEAAV---PGAAVYRSPGAAVYRSRGAAVYRSRGAAVYRSRGAAVYRSPGAA 806
Query: 343 VDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEAL 401
V S + + S E ++ SPE ++ P+ + P+ ++ SPEA++ PE S+
Sbjct: 807 VYRSREAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHS 866
Query: 402 PEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEAS 461
PE +V +PE ++ P + +P +V SP ++ SP A V SP ++ S A+
Sbjct: 867 PEAAVYHSPEAAVFHSPGAAVFHSPGAAVFHSPGAAVYRSPGAAVYRSPGAAVYRSPGAA 926
Score = 49.7 bits (117), Expect = 1e-05
Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 7/140 (5%)
Query: 322 SPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVS 381
SP A V + E + P +V SP + Y SPE ++ P+ + P+ +
Sbjct: 802 SPGAAVYRSREAAVFRSPEAAVYRSPEAAVY-------RSPEAAVFHCPEAAVYHSPEAA 854
Query: 382 IVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEAS 441
+ SPEAS+ PE ++ PE +V +P ++ P + +P +V SP ++ S
Sbjct: 855 VYHSPEASVFHSPEAAVYHSPEAAVFHSPGAAVFHSPGAAVFHSPGAAVYRSPGAAVYRS 914
Query: 442 PEAMVKASPKTSLEASMEAS 461
P A V SP ++ S A+
Sbjct: 915 PGAAVYRSPGAAVYRSPGAA 934
Score = 49.3 bits (116), Expect = 2e-05
Identities = 43/150 (28%), Positives = 73/150 (48%), Gaps = 8/150 (5%)
Query: 322 SPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSE-MSMDASPELSIEALPKVDLETVPKV 380
SP+A V +PE + P +V SP + Y S ++ S ++ + P
Sbjct: 749 SPEAAVYRSPEAAV---PGAAVYRSPGAAVYRSRGAAVYRSRGAAVYRSRGAAVYRSPGA 805
Query: 381 SIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEA 440
++ S EA++ PE ++ PE +V +PE ++ P+ + +P+ +V SP+ S+
Sbjct: 806 AVYRSREAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFH 865
Query: 441 SPEAMVKASPKTSLEASMEASPKAKARDAP 470
SPEA V SP EA++ SP A +P
Sbjct: 866 SPEAAVYHSP----EAAVFHSPGAAVFHSP 891
Score = 47.8 bits (112), Expect = 5e-05
Identities = 49/197 (24%), Positives = 83/197 (42%), Gaps = 1/197 (0%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P + + P+ V SP V P+A+V P+ V S+ SP A
Sbjct: 381 SPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGA 440
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDSE-MSMDASPELSIEALPKVDLETVPKVSIVA 384
V +P + P +V SP + Y S ++ SP ++ P + P ++
Sbjct: 441 AVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFH 500
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
SP A++ P ++ P +V +P ++ P + +P +V SP ++ SP A
Sbjct: 501 SPGAAVYHSPGAAVFHSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGA 560
Query: 445 MVKASPKTSLEASMEAS 461
V SP ++ S A+
Sbjct: 561 AVFRSPGAAVYRSPGAA 577
Score = 47.8 bits (112), Expect = 5e-05
Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 1/190 (0%)
Query: 266 SDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKA 325
S E P +++ P+ V SP V P A+V P V ++ SP A
Sbjct: 850 SPEAAVYHSPEASVFHSPEAAVYHSPEAAVFHSPGAAVFHSPGAAVFHSPGAAVYRSPGA 909
Query: 326 GVGMAPEVSTDSFPVVSVDVSPVVSTYDSE-MSMDASPELSIEALPKVDLETVPKVSIVA 384
V +P + P +V SP + Y S ++ SP ++ P + P ++
Sbjct: 910 AVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVFRSPGAAVYRSPGAAVFR 969
Query: 385 SPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEA 444
SP A++ P ++ P +V +P ++ P + +P +V SP ++ PEA
Sbjct: 970 SPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVFRCPEA 1029
Query: 445 MVKASPKTSL 454
V SP+ ++
Sbjct: 1030 AVYHSPEATV 1039
Score = 37.7 bits (86), Expect = 0.047
Identities = 51/214 (23%), Positives = 85/214 (39%), Gaps = 32/214 (14%)
Query: 283 PQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVS 342
P V SP V P A+V P V ++ S A V + + +
Sbjct: 670 PGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSRGAAVYRSRGAAVYRSRGAA 729
Query: 343 VDVSPVVSTYDS-EMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAP-------- 393
V SP + Y S E ++ SPE ++ P+ VP ++ SP A++
Sbjct: 730 VYRSPGAAVYRSREAAVFRSPEAAVYRSPEA---AVPGAAVYRSPGAAVYRSRGAAVYRS 786
Query: 394 ----------------PEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKES 437
P ++ E +V +PE ++ P+ + +P+ +V P+ +
Sbjct: 787 RGAAVYRSRGAAVYRSPGAAVYRSREAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAA 846
Query: 438 MEASPEAMVKASPKTSLEASMEASPKAKARDAPK 471
+ SPEA V SP EAS+ SP+A +P+
Sbjct: 847 VYHSPEAAVYHSP----EASVFHSPEAAVYHSPE 876
Score = 33.9 bits (76), Expect = 0.68
Identities = 53/226 (23%), Positives = 82/226 (36%), Gaps = 40/226 (17%)
Query: 283 PQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVS 342
P V SP V P A+V P V ++ SP A V +P + P +
Sbjct: 923 PGAAVYRSPGAAVYRSPGAAVFRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAA 982
Query: 343 VDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALP 402
V SP + Y SP ++ P + P ++ SP A++ PE ++ P
Sbjct: 983 VFRSPGAAVY-------RSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVFRCPEAAVYHSP 1035
Query: 403 EVSVEAA-----------------------PEG-SLEAPPKGSAEVAPKESVKGSPKESM 438
E +V A P G SL + P+ P +P+
Sbjct: 1036 EATVYPAWRRGESDSAETNFQDRTPIGGPGPRGPSLRSHPRS----GPCAGKPRAPRSRG 1091
Query: 439 EASPEAMVKASPKTSLEASME---ASPKAKARDAPKKSEMDKQALI 481
A P + A+P A+ A+ARDA +SE ++A +
Sbjct: 1092 AAEPPSRRVAAPGVGTAGGANKAAATRAAQARDA--RSERPRRAFV 1135
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 67.8 bits (164), Expect = 4e-11
Identities = 133/623 (21%), Positives = 229/623 (36%), Gaps = 50/623 (8%)
Query: 241 ERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPK 300
E P++ V+ ++ ++ E V+ T +T+V E E+ E K
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQT----EETQVTEEVTEEEEKEAK 479
Query: 301 ASVDAPPQVNVEVFCNTSMEA--SPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSM 358
+ E E SP A +PE S PV SP +
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS-PVKEEAKSPAEAK------- 531
Query: 359 DASPELSIEALPKVDLETVPKVSIVASPEAS----LEAPPEVSLEALPEVSVEAAPEGSL 414
SPE EA ++++ K A EA ++P + ++ EV +
Sbjct: 532 --SPEKE-EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA 588
Query: 415 EAPPKGSAEVAPKESVKGSPKESMEASPEAM--VKASPKTSLEASMEASPKAKARDAPKK 472
+ K AE E K KE ++ EA VK K+ E K+ ++ K
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 473 SEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQ 532
E K AK + + + SPE A SP+ + + SP+ +K
Sbjct: 649 PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA---KSPVKAEAKSPEKAK-SPVKEEAKS 704
Query: 533 SPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAG 592
+ P K + S + A S VK++ +T K + + ++ + T
Sbjct: 705 PEKAKSPVK----EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760
Query: 593 IMNAEAATKILTELRRLAREQREKEE----EERQREEMQQRVIKKSKDMAKEAVGGQAED 648
+ + EA T E R A + EK + EE + E + +K+ ++ + + E
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV 820
Query: 649 HLKLKDGQQQNETKKKKGWLDQEDQEAPL-----QKGDAKIK--AQEEADKRKKEH--ER 699
+K+ ++ E K K+ E+++AP +K D+K + ++EA K K E E
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 880
Query: 700 IMLQNLQERLERKKRIEEIMKRTRKTDVNA-SKVTETSSHDIYEEAEADNEESDKDSLNE 758
+ + + ++E KK E K+ + A +KV E+ E +E D E
Sbjct: 881 AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Query: 759 MFPSAILNGTGSPTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSM 818
A +P K AKK K ++ +++ KT K +K+
Sbjct: 941 PSKPA-EKKEAAPEKKDTKEEKAKKPEEK----PKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Query: 819 KDTSIQEVVSRPSSKRMTSHTTK 841
K +S + S+P K K
Sbjct: 996 KSSSTDQKDSKPPEKATEDKAAK 1018
Score = 55.5 bits (132), Expect = 2e-07
Identities = 127/624 (20%), Positives = 219/624 (35%), Gaps = 75/624 (12%)
Query: 75 RREEKRRQ-QDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQ 133
+ EEK + + + KET ++E++ + E+ EE +++ KE + KEE+ EE+ +
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE---GGEEEEAE 495
Query: 134 KDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGT 193
E + + A + E+ + ++ + A A S K K A + E+
Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSPVKEEAK----SPAEAKSPEKEEAKSPAEVKSPEKAK 551
Query: 194 SALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTG---VT 250
S P AK +E S + S KE+A+
Sbjct: 552 S------PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605
Query: 251 NYVMQYVTVP--LRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQ 308
+ V + P + +E ++ S K TK E EK ++P K +P +
Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Query: 309 VNVEVFCNTSMEASPKAGV---GMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELS 365
V K+ V +PE + PV SP S + +A
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS--PVKEEAKSP--EKAKSPVKEEAKSPEK 721
Query: 366 IEALPKVDLETVPKVSI-----VASPEASLEAPPEVSLEA-LPEVSVEAAPEGSLEA--- 416
++ K + +T K SPE + +L+ PE A E A
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF 781
Query: 417 PPKGSA----EVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKK 472
P K + EV E K KE +A + + K S E + K ++ PKK
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK 841
Query: 473 SEMDKQALIPIAKKRLSSYTECYKWSSSP--------ENACGLPSPISTNRQIQKNCPPS 524
+E +K P +++ S E +P E A P + ++
Sbjct: 842 AEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901
Query: 525 PLPLISKQSP-QTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYE 583
+P K++P + P + T + K K+ SK + EA ++ E
Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP--SKPAEKKEAAPEKKDTKE 959
Query: 584 ESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKK-SKDMAKEAV 642
E A++ EK + E + +E + + K+ SK A++A
Sbjct: 960 EK------------------------AKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Query: 643 GGQAEDHLKLKDGQQQNETKKKKG 666
+ D K ++ E K KG
Sbjct: 996 KSSSTDQKDSKPPEKATEDKAAKG 1019
Score = 40.8 bits (94), Expect = 0.006
Identities = 36/188 (19%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
K+ +K+ + + + ++DA + + K+ + K +++ + ++ K+KE +K E+
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 124 RIAAEEKRHQKDEAQKE---KFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTAN 180
+ A K +K +++KE K A + E++ A + ++ A + K
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT 905
Query: 181 KRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTD----KERSSSLNRRDSNLHSSTD 236
+ K+E A ++ + VAK++ D KE S ++++
Sbjct: 906 PEKEAPAKVEVKEDAKPKE--------KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 957
Query: 237 KEQAERKP 244
KE+ +KP
Sbjct: 958 KEEKAKKP 965
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 67.4 bits (163), Expect = 6e-11
Identities = 120/560 (21%), Positives = 201/560 (35%), Gaps = 61/560 (10%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQ----MEERQRKLKERKEKEEQR 123
++R R+R E+ R++D +E + E+ER+ + + +K+ EE +R+ +R EK+ Q
Sbjct: 408 RERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQH 467
Query: 124 RIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRS 183
R EK +K++ + + + R A+ +++ + G E K +RS
Sbjct: 468 RDRDREKEREKEKGKPKPRS-----PQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRS 522
Query: 184 ASTEK-----LEQGTSALIRQMPLSSAGLQNS--VAKRKTDKERSSSLNRRDSNLHSSTD 236
S +K + + R+ SSA NS + R + S S R + S+
Sbjct: 523 KSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSY 582
Query: 237 KEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVE 296
++ R +G + + + P T R + PP K E ++K
Sbjct: 583 SSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGE-PAPPPGKAGEKSVKKPA 641
Query: 297 TPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFP--------VVSVDVSPV 348
PP APPQ T+ G E P +S S
Sbjct: 642 PPP-----APPQAT-----KTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGS 691
Query: 349 VSTYDSEMSMDASPELSIEALPKVDLETVPKVSI-----------VASPEASLEAPPEVS 397
S+Y S S LS+ ++ V T S +ASP +S +
Sbjct: 692 GSSYSGSSSRSRS--LSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAP 749
Query: 398 LEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVK---GSPKESMEASPEAMVKASPKTSL 454
+ E +G E K + P +S K G ++P+ P+
Sbjct: 750 AQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGT 809
Query: 455 -----EASMEASPKAKARDAPKKSE-MDKQALIPIAKKRLSSYTECYKWSSSPENACGLP 508
E + KA + + K+ E DK P KR ++ + G P
Sbjct: 810 FVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSP 869
Query: 509 SPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKT 568
P Q K P +P + SPQ+ K+ + S A+ST K T+S+
Sbjct: 870 KPERQRGQNSK-APAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSR- 927
Query: 569 TNRCEALSQRHMIYEESGNK 588
R E L Q + + K
Sbjct: 928 --REELLKQLKAVEDAIARK 945
Score = 32.3 bits (72), Expect = 2.0
Identities = 49/251 (19%), Positives = 100/251 (39%), Gaps = 33/251 (13%)
Query: 613 QREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQED 672
+RE+E E RQRE ++R +D +E + + + ++ ++ E +++K E+
Sbjct: 405 ERERERENRQRERERER----ERDRERER---RQREREREREHERDKERQRRK-----EE 452
Query: 673 QEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKV 732
E K D K + + D R+KE E+ E+ + K R + R + +
Sbjct: 453 WERERAKRDEKDRQHRDRD-REKEREK-------EKGKPKPRSPQPPSRQAEPPKKEAAT 504
Query: 733 T--ETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNNAKKMTHKLVF 790
T + D +++ ++ K + PS + N+++ + +
Sbjct: 505 TGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSY 564
Query: 791 LEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTTKTRKADETNT 850
G+S+ R +Y + ++ R S SR S+ +S + + T +
Sbjct: 565 SGSGSSRSRSRSSSYSSYSSRSSRHSSFSG-------SRSRSRSFSSSPSPS----PTPS 613
Query: 851 TSRSSAQTKSE 861
R S +TK E
Sbjct: 614 PHRPSIRTKGE 624
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 66.6 bits (161), Expect = 9e-11
Identities = 84/340 (24%), Positives = 131/340 (38%), Gaps = 46/340 (13%)
Query: 244 PRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASV 303
P+V V+ VP+ E+ P P+ KV E+ K E+PP
Sbjct: 10523 PKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVP 10582
Query: 304 DAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSP-----VVSTYDSEMSM 358
+AP +V E + P+ PE + P V V P V T E+
Sbjct: 10583 EAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPK 10642
Query: 359 DASPELSI-EALP---------------KVDLETVPKVSIVASPEASLEAPPEVSLEALP 402
A PE + EA+P +V LE P +V PE + APP+V++
Sbjct: 10643 VAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEE-PPAEVVEEPEPA--APPQVTVPPKK 10699
Query: 403 EVSVEAAPEGSLEAP-------PKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLE 455
V + AP + P P+ EV P++ V + EA P A V PK +
Sbjct: 10700 PVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA-PPAKVPEVPKEVVP 10758
Query: 456 ASMEASPK------AKARDAPKKSEMDKQALIPIAKKRLSSYTECY----KWSSSPENAC 505
A PK AK + PKK ++++ +P+ ++ S E Y + + E A
Sbjct: 10759 EKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAP 10818
Query: 506 GLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPI 545
P+ + + PP +P + P+ P K +P+
Sbjct: 10819 EEEKPVPVAEEEEPEVPPPAVP----EEPKKIIPEKKVPV 10854
Score = 60.5 bits (145), Expect = 7e-09
Identities = 102/474 (21%), Positives = 181/474 (38%), Gaps = 53/474 (11%)
Query: 261 LRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSME 320
L+K +E V P PP KV E P + E + S+ + V
Sbjct: 9815 LKKAVPEEKVPVPIPKKLK--PPPPKVPEEPKKVFEEKIRISITKREKEQV--------- 9863
Query: 321 ASPKAGVGMAPE--VSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVP 378
P A V M P+ V+ + PV +V+P V E+ + PE E + ++ T
Sbjct: 9864 TEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRV--PEVPKELEPE---EVAFEEEVVTHV 9918
Query: 379 KVSIVASPEASLEAPPEVSLEA---------LPEVSVEAAPEGSLEAPPKGSAEVAPKES 429
+ +V E + E E +PEV + PE P E AP
Sbjct: 9919 EEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKE-APPAK 9977
Query: 430 VKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLS 489
V PK+ E P + K E P AK + PKK +++ +P+ KK +
Sbjct: 9978 VPEVPKKPEEKVPVLIPKK----------EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEA 10027
Query: 490 SYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTL 549
+ + P +P P + PP+ +P + P+ P + P
Sbjct: 10028 PPAKVPEVPKKPVPEKKVPVPAPK----KVEAPPAKVP----EVPKKLIPEEKKPTPVPK 10079
Query: 550 SVQSASSTVKKKKETVS---KTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTEL 606
V++ V KK+E V E L + ++ EE ++ E ++L E
Sbjct: 10080 KVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE--EEVLPEE 10137
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETK--KK 664
+ E+ E EE + ++ V ++ + + +E V + + + + + + K +K
Sbjct: 10138 EEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEK 10197
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEI 718
K + ++++ P + + K +E+ KE E + ++ +E E EEI
Sbjct: 10198 KVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEI 10251
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/296 (24%), Positives = 108/296 (36%), Gaps = 30/296 (10%)
Query: 275 PMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEV- 333
P + KI P K + + E P K + P ++ VE E P+ PEV
Sbjct: 10443 PEISEKIIPPKKPPTKVVPRKEPPAKVP-EVPKKIVVEEKVRVPEE--PRVPPTKVPEVL 10499
Query: 334 -STDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEA 392
+ P V V P PE +P+ E VP+ + P E
Sbjct: 10500 PPKEVVPEKKVPVPPA-----------KKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEV 10548
Query: 393 P----PEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKA 448
P PEV A+PE V A E+PP E APKE V P++ + A+P +
Sbjct: 10549 PPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPE-APKEVV---PEKKVPAAPPKKPEV 10604
Query: 449 SPKTSLEASMEASPKAKAR-DAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGL 507
+P EA E P+ K PKK E+ + + K + PE+
Sbjct: 10605 TPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPES---- 10660
Query: 508 PSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKE 563
P P + P ++ + P P +P + + + A + V KK E
Sbjct: 10661 PPPEVFEEPEEVALEEPPAEVVEEPEPAAP-PQVTVPPKKPVPEKKAPAVVAKKPE 10715
Score = 46.6 bits (109), Expect = 1e-04
Identities = 110/628 (17%), Positives = 230/628 (36%), Gaps = 86/628 (13%)
Query: 36 KQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERREEKRRQQDANKETQLLEKE 95
++++V + ++ I + +ID S ++K ++E ++ ++ ++ Q + KE
Sbjct: 9006 REEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKE 9065
Query: 96 RKTKLQ-YEKQMEE----------RQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTA 144
++ ++ +E+ +E Q +E E E+ ++ A+++ H++ E E+
Sbjct: 9066 KRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQE 9125
Query: 145 ILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSS 204
R + Y + W + + + + + + ++ P
Sbjct: 9126 YYERE-------EGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPP 9178
Query: 205 AGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKC 264
++ V ++ R + K+ +KP T V V++ V VP
Sbjct: 9179 KVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIE-VKVP---- 9233
Query: 265 TSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPK 324
+ + ++ M T+ E S T P+ + + + V + +E PK
Sbjct: 9234 -AVHTKKMVISEEKMFFASHTEEEVSV-----TVPEVQKEIVTEEKIHVAISKRVEPPPK 9287
Query: 325 AGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLET-VPKVSIV 383
PE+ P +V+PV E PE+ + +P+ VPK
Sbjct: 9288 V-----PELPEKPAPE---EVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPA 9339
Query: 384 ASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEV----APKESV------KGS 433
A P+ PEV + +PE + EAPP EV +E + + S
Sbjct: 9340 APPKV-----PEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREES 9394
Query: 434 PKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQAL--IPIAKKRLSSY 491
P ++ P+ V K E P K PKK +++ +P+AKK
Sbjct: 9395 PPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKK----- 9449
Query: 492 TECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSV 551
P P ++ K ++++ + P ++ +H +S
Sbjct: 9450 ---------------APPP---RAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSA 9491
Query: 552 QSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAR 611
+ S +++E VS + R E + EE + +M + +L +++
Sbjct: 9492 EEEWS-YSEEEEGVSISVYREEEREE-----EEEAEVTEYEVMEEPEEYVVEEKLHIISK 9545
Query: 612 EQREKEEEERQREEMQQRVIKKSKDMAK 639
+ E +R+E ++++ K K AK
Sbjct: 9546 RVEAEPAEVTERQE--KKIVLKPKIPAK 9571
Score = 43.5 bits (101), Expect = 9e-04
Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 40/215 (18%)
Query: 275 PMSTMKIPPQTKV-----EESPLEKV--ETPPKASVDAP-PQVNVEV----FCNTSMEAS 322
P ++PP+ + E P E+V E PK V AP P++ +V E +
Sbjct: 10148 PPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEA 10207
Query: 323 PKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSI 382
P A V P+ V+ ++ + E+ L +E + + E + + I
Sbjct: 10208 PPAKVPEVPK---------KVEEKRIILPKEEEV-------LPVEVTEEPEEEPISEEEI 10251
Query: 383 VASPEASLEAPPEVSLEALPEVSVEAAPEG------SLEAPPKGSAEVAPKESVKGSPKE 436
P S+E EV+ +PEV +A PE +EAPP ++ P+E V P +
Sbjct: 10252 PEEPP-SIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVP-VPVQ 10309
Query: 437 SMEAS----PEAMVKASPKTSLEASMEASPKAKAR 467
EA PE K K L EA P AK R
Sbjct: 10310 KKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGR 10344
Score = 40.0 bits (92), Expect = 0.009
Identities = 78/370 (21%), Positives = 122/370 (32%), Gaps = 89/370 (24%)
Query: 275 PMSTMKIPPQTKV-----EESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGM 329
P ++PP KV + P EKV P + APP P+A V
Sbjct: 9415 PRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPP---------------PRAEVSK 9459
Query: 330 APEVSTDSFPV---VSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASP 386
V F +S V V E+S + S E E +S+
Sbjct: 9460 KTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEE-------EEGVSISVYREE 9512
Query: 387 EASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMV 446
E E EV+ + E E E L K V+ P E E + +V
Sbjct: 9513 EREEEEEAEVTEYEVMEEPEEYVVEEKLHIISK---------RVEAEPAEVTERQEKKIV 9563
Query: 447 KASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACG 506
K + A +E P AK +APKK +K+ P+ KK
Sbjct: 9564 L---KPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKK-------------------- 9600
Query: 507 LPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVS 566
+ PP +P + P+ P K +P +K ++ +
Sbjct: 9601 ------------EKVPPPKVP----EEPKKPVPEKKVP----------PKVIKMEEPLPA 9634
Query: 567 KTTNRCEALSQRHMIYEESGNKSTAGIMNA-EAATKILTELRRLAREQREKEEEERQREE 625
K T R ++Q + K E + + E + L + + +EE + E
Sbjct: 9635 KVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTE 9694
Query: 626 MQQRVIKKSK 635
++RV+K+ K
Sbjct: 9695 FRKRVVKEEK 9704
Score = 39.3 bits (90), Expect = 0.016
Identities = 50/223 (22%), Positives = 82/223 (36%), Gaps = 17/223 (7%)
Query: 275 PMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVS 334
P+ K+PP+ E PL T + +V V V T EA PKA V P+ +
Sbjct: 9615 PVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAV---TKKEAPPKARVPEEPKRA 9671
Query: 335 TDSFPVVSV----DVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEAS- 389
V+ + + P + + ++SIEA PK + + + +V+I+ E +
Sbjct: 9672 VPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEA-PKREPQPIKEVTIMEEKERAY 9730
Query: 390 ------LEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPE 443
+ E E E + E E +E + E PE
Sbjct: 9731 TLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPE 9790
Query: 444 AMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKK 486
+ P E + PKA KK+ +++ +PI KK
Sbjct: 9791 KPIPVKPVP--EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKK 9831
Score = 39.3 bits (90), Expect = 0.016
Identities = 57/234 (24%), Positives = 88/234 (37%), Gaps = 35/234 (14%)
Query: 280 KIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEV--STDS 337
K P KV E P K PP V ++F ++A PK V P+V +
Sbjct: 10864 KEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIF---QLKAIPKKKVPEKPQVPEKVEL 10920
Query: 338 FPVVSVDVSPVVSTYDSEMSMDASPELSIEAL---------PKVDLETVPKVSIVASPEA 388
P+ V E + E+ ++++ PKV+ + + KV A PE
Sbjct: 10921 TPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEP 10980
Query: 389 -------SLEAPPEVSLEA-------LPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSP 434
+E P E +PE+ A P + E PK AEV + P
Sbjct: 10981 PPPKPVEEVEVPTVTKRERKIPEPTKVPEIK-PAIPLPAPEPKPKPEAEVKTIKPPPVEP 11039
Query: 435 KESMEASPEAMVKASPKTSLEASME--ASPKAKARDAPKKS----EMDKQALIP 482
+ + A+P + K +A E A PK + PKK+ E +++ L P
Sbjct: 11040 EPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRP 11093
Score = 35.8 bits (81), Expect = 0.18
Identities = 57/244 (23%), Positives = 92/244 (37%), Gaps = 23/244 (9%)
Query: 262 RKCTSDELRAVMFPMSTMKIPPQTKVEESPL---EKVETPPKASVDAPPQVNV---EVFC 315
+K +E AV P++ PP+ +V + + ++ K S P +V V EV
Sbjct: 9432 KKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSA 9491
Query: 316 NTSMEASPKA-GVGMA-----PEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEAL 369
S + GV ++ + V +V Y E + + +EA
Sbjct: 9492 EEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISK-RVEAE 9550
Query: 370 PKVDLETVPKVSIVASPE--ASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEV--- 424
P E K IV P+ A +E PP + PE + PE + AP +V
Sbjct: 9551 PAEVTERQEK-KIVLKPKIPAKIEEPPPAKV---PEAPKKIVPEKKVPAPVPKKEKVPPP 9606
Query: 425 -APKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPI 483
P+E K P++ + M + P E M+ + + K A K E +A +P
Sbjct: 9607 KVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPE 9666
Query: 484 AKKR 487
KR
Sbjct: 9667 EPKR 9670
Score = 35.4 bits (80), Expect = 0.23
Identities = 68/292 (23%), Positives = 120/292 (41%), Gaps = 68/292 (23%)
Query: 461 SPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKN 520
+P+ K + PK+ E+ K+A+ AKK ++ P ++ +I K
Sbjct: 8971 TPEEK-KPPPKRIEVTKKAVKKDAKKVVAK-----------------PKEMTPREEIVKK 9012
Query: 521 CPPSPLPLISKQSPQT------SFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEA 574
PP P LI ++P+ + KIM I VQ V +KK+ V K
Sbjct: 9013 -PPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHK------- 9064
Query: 575 LSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKS 634
++ ES E ++ E EQ EE + EE+
Sbjct: 9065 ---EKRVFIESFE---------EPYDELEVEPYTEPFEQPYYEEPDEDYEEI-------- 9104
Query: 635 KDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRK 694
K AK+ V + E+ ++GQ+ E +++G+ + E++ + I+ Q+E +
Sbjct: 9105 KVEAKKEVHEEWEE--DFEEGQEYYE--REEGYDEGEEEWEEAYQEREVIQVQKEV--YE 9158
Query: 695 KEHERIMLQNLQE-------RLERKKRIEEIMKRTRKTD---VNASKVTETS 736
+ HER + + E ++ +K IE+I K +R+ + V +KV E S
Sbjct: 9159 ESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVS 9210
Score = 31.6 bits (70), Expect = 3.4
Identities = 39/176 (22%), Positives = 70/176 (39%), Gaps = 28/176 (15%)
Query: 94 KERKTKLQYEKQMEERQRKLKERKEKEEQRRI----------------AAEEKRHQKDEA 137
+ER + Y +Q ++RQR + ER+++E R + + EEK +K
Sbjct: 32179 RERHAQAAY-RQPKQRQRIMAEREDEELLRPVTTTQHLSEYKSELDFMSKEEKSRKKSRR 32237
Query: 138 QKEKFTAILYRTLERRRLADDYQ-QKRWSWGGSAMANSESKTANKRSASTEKLEQGTSAL 196
Q+E E + ++Y+ K S+ A+ + S + +L + S L
Sbjct: 32238 QRE--------VTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSEL 32289
Query: 197 IRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNY 252
IR P + ++ +R ER+ R S + S + ER R + Y
Sbjct: 32290 IRSRPQPAEEYEDDTERRSPTPERTRP--RSPSPVSSERSLSRFERSARFDIFSRY 32343
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 65.1 bits (157), Expect = 3e-10
Identities = 80/342 (23%), Positives = 117/342 (34%), Gaps = 33/342 (9%)
Query: 234 STDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLE 293
+T KE A P+ T T P + A +T K P T + +P
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP----TTTKEPAPTTTKSAPTT 414
Query: 294 KVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYD 353
E P + + P E T + +P AP + P + +P
Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474
Query: 354 SEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGS 413
+ +P+ + PK T P+ +PE PE PE PE
Sbjct: 475 AP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP 530
Query: 414 LEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPK----TSLEASMEASPKAKARDA 469
PK +A PKE +PKE +P+ +PK T+ + + + K A
Sbjct: 531 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 590
Query: 470 PKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLI 529
PKK + L P K +S T C P+P +T + P P P
Sbjct: 591 PKKPA--PKELAPTTTKEPTSTT------------CDKPAP-TTPKGTAPTTPKEPAPTT 635
Query: 530 SKQSPQTSFPYKIMPIQHTLSVQSASSTVKK--KKETVSKTT 569
K+ P + P P T + A +T KK KE TT
Sbjct: 636 PKE-PAPTTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTT 673
Score = 54.7 bits (130), Expect = 4e-07
Identities = 93/405 (22%), Positives = 147/405 (36%), Gaps = 58/405 (14%)
Query: 168 GSAMANSESKTANKRSASTEKLEQGTSALIRQM-PLSSAGLQNSVAKRKTDKERSSSLNR 226
GS + N + K +++T+ + TS I P++ + T KE S ++N+
Sbjct: 89 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTVNK 146
Query: 227 RDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTK 286
T E E T TN Q T K TS + + S + P +K
Sbjct: 147 E-------TTVETKE-----TTTTN--KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192
Query: 287 VEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVS 346
V P K ET K P+ +PK P+ T + ++ +
Sbjct: 193 VLAKPTPKAETTTKGPALTTPK--------EPTPTTPKEPASTTPKEPTPT----TIKSA 240
Query: 347 PVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSV 406
P + + ++P E P E P +P + E P + A P
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA-PTTPK 299
Query: 407 EAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKA 466
E AP PK A PKE +PKE +P+ P + + +PK A
Sbjct: 300 EPAP-----TTPKKPAPTTPKEPAPTTPKEPTPTTPK-----EPAPTTKEPAPTTPKEPA 349
Query: 467 RDAPKK-SEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPS- 524
APKK + + P K + T ++P+ P+P +T K+ P +
Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTT-----KSAPTTT 400
Query: 525 --PLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSK 567
P P +K +P T P + P T + + A +T K+ T K
Sbjct: 401 KEPAPTTTKSAPTT--PKEPSP---TTTKEPAPTTPKEPAPTTPK 440
Score = 52.4 bits (124), Expect = 2e-06
Identities = 81/420 (19%), Positives = 143/420 (34%), Gaps = 67/420 (15%)
Query: 216 TDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKC-TSDELRAVMF 274
T KE + + ++ + +T KE A P+ T T T P + T+ E A
Sbjct: 454 TPKEPAPTTTKKPA---PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510
Query: 275 PMSTMKIPPQTKVEESPLEKVETPPKASV-------------DAPPQVNVEVFCNTSMEA 321
P P+ +P E T PKA+ + P E T E
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570
Query: 322 SPKAGVGMAPEVSTDSFPVVSV-----DVSPVVSTYDSEMSMD----ASPELSIEALPKV 372
+P G AP + P +++P + + + D +P+ + PK
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630
Query: 373 DLETVPKVSIVASPEASL-----EAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPK 427
T PK +P+ + E P + P+ +G A PK
Sbjct: 631 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 690
Query: 428 ESVKGSPKESMEASPEAMVKASPKTSLEASMEAS-------------------PKAKARD 468
E+ +PKE +P+ +P+T + E S P+ A
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 750
Query: 469 APKKSE-MDKQALIPIAKKRLSSYTECYKWS----------SSPENACGLP----SPIST 513
PK E K+ +P K ++ E + ++PE P +T
Sbjct: 751 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 810
Query: 514 NRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCE 573
+ ++ + ++ + Q + P+KI ++ T ++T KK T ++ N+ E
Sbjct: 811 TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT--KKTITTTEIMNKPE 868
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 65.1 bits (157), Expect = 3e-10
Identities = 80/342 (23%), Positives = 117/342 (34%), Gaps = 33/342 (9%)
Query: 234 STDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLE 293
+T KE A P+ T T P + A +T K P T + +P
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP----TTTKEPAPTTTKSAPTT 455
Query: 294 KVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYD 353
E P + + P E T + +P AP + P + +P
Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515
Query: 354 SEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGS 413
+ +P+ + PK T P+ +PE PE PE PE
Sbjct: 516 AP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP 571
Query: 414 LEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPK----TSLEASMEASPKAKARDA 469
PK +A PKE +PKE +P+ +PK T+ + + + K A
Sbjct: 572 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 631
Query: 470 PKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLI 529
PKK + L P K +S T C P+P +T + P P P
Sbjct: 632 PKKPA--PKELAPTTTKEPTSTT------------CDKPAP-TTPKGTAPTTPKEPAPTT 676
Query: 530 SKQSPQTSFPYKIMPIQHTLSVQSASSTVKK--KKETVSKTT 569
K+ P + P P T + A +T KK KE TT
Sbjct: 677 PKE-PAPTTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTT 714
Score = 54.7 bits (130), Expect = 4e-07
Identities = 93/405 (22%), Positives = 147/405 (36%), Gaps = 58/405 (14%)
Query: 168 GSAMANSESKTANKRSASTEKLEQGTSALIRQM-PLSSAGLQNSVAKRKTDKERSSSLNR 226
GS + N + K +++T+ + TS I P++ + T KE S ++N+
Sbjct: 130 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTVNK 187
Query: 227 RDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTK 286
T E E T TN Q T K TS + + S + P +K
Sbjct: 188 E-------TTVETKE-----TTTTN--KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233
Query: 287 VEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVS 346
V P K ET K P+ +PK P+ T + ++ +
Sbjct: 234 VLAKPTPKAETTTKGPALTTPK--------EPTPTTPKEPASTTPKEPTPT----TIKSA 281
Query: 347 PVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSV 406
P + + ++P E P E P +P + E P + A P
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA-PTTPK 340
Query: 407 EAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKA 466
E AP PK A PKE +PKE +P+ P + + +PK A
Sbjct: 341 EPAP-----TTPKKPAPTTPKEPAPTTPKEPTPTTPK-----EPAPTTKEPAPTTPKEPA 390
Query: 467 RDAPKK-SEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPS- 524
APKK + + P K + T ++P+ P+P +T K+ P +
Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTT-----KSAPTTT 441
Query: 525 --PLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSK 567
P P +K +P T P + P T + + A +T K+ T K
Sbjct: 442 KEPAPTTTKSAPTT--PKEPSP---TTTKEPAPTTPKEPAPTTPK 481
Score = 52.4 bits (124), Expect = 2e-06
Identities = 81/420 (19%), Positives = 143/420 (34%), Gaps = 67/420 (15%)
Query: 216 TDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKC-TSDELRAVMF 274
T KE + + ++ + +T KE A P+ T T T P + T+ E A
Sbjct: 495 TPKEPAPTTTKKPA---PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551
Query: 275 PMSTMKIPPQTKVEESPLEKVETPPKASV-------------DAPPQVNVEVFCNTSMEA 321
P P+ +P E T PKA+ + P E T E
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611
Query: 322 SPKAGVGMAPEVSTDSFPVVSV-----DVSPVVSTYDSEMSMD----ASPELSIEALPKV 372
+P G AP + P +++P + + + D +P+ + PK
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671
Query: 373 DLETVPKVSIVASPEASL-----EAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPK 427
T PK +P+ + E P + P+ +G A PK
Sbjct: 672 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 731
Query: 428 ESVKGSPKESMEASPEAMVKASPKTSLEASMEAS-------------------PKAKARD 468
E+ +PKE +P+ +P+T + E S P+ A
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 791
Query: 469 APKKSE-MDKQALIPIAKKRLSSYTECYKWS----------SSPENACGLP----SPIST 513
PK E K+ +P K ++ E + ++PE P +T
Sbjct: 792 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 851
Query: 514 NRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCE 573
+ ++ + ++ + Q + P+KI ++ T ++T KK T ++ N+ E
Sbjct: 852 TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT--KKTITTTEIMNKPE 909
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 65.1 bits (157), Expect = 3e-10
Identities = 80/342 (23%), Positives = 117/342 (34%), Gaps = 33/342 (9%)
Query: 234 STDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLE 293
+T KE A P+ T T P + A +T K P T + +P
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP----TTTKEPAPTTTKSAPTT 507
Query: 294 KVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYD 353
E P + + P E T + +P AP + P + +P
Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567
Query: 354 SEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGS 413
+ +P+ + PK T P+ +PE PE PE PE
Sbjct: 568 AP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP 623
Query: 414 LEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPK----TSLEASMEASPKAKARDA 469
PK +A PKE +PKE +P+ +PK T+ + + + K A
Sbjct: 624 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 683
Query: 470 PKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLI 529
PKK + L P K +S T C P+P +T + P P P
Sbjct: 684 PKKPA--PKELAPTTTKEPTSTT------------CDKPAP-TTPKGTAPTTPKEPAPTT 728
Query: 530 SKQSPQTSFPYKIMPIQHTLSVQSASSTVKK--KKETVSKTT 569
K+ P + P P T + A +T KK KE TT
Sbjct: 729 PKE-PAPTTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTT 766
Score = 57.8 bits (138), Expect = 4e-08
Identities = 105/489 (21%), Positives = 176/489 (35%), Gaps = 72/489 (14%)
Query: 95 ERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRR 154
++KTK E + + + E +E ++ +K ++ K + R L+++
Sbjct: 101 KKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKN---SAANRELQKKL 157
Query: 155 LADDYQQKRWSW-----------GGSAMANSESKTANKRSASTEKLEQGTSALIRQM-PL 202
D ++ R GS + N + K +++T+ + TS I P+
Sbjct: 158 KVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 217
Query: 203 SSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLR 262
+ + T KE S ++N+ T E E T TN Q T
Sbjct: 218 NPR--PSLPPNSDTSKETSLTVNKE-------TTVETKE-----TTTTN--KQTSTDGKE 261
Query: 263 KCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEAS 322
K TS + + S + P +KV P K ET K P+ +
Sbjct: 262 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK--------EPTPTT 313
Query: 323 PKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSI 382
PK P+ T + ++ +P + + ++P E P E P
Sbjct: 314 PKEPASTTPKEPTPT----TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 369
Query: 383 VASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASP 442
+P + E P + A P E AP PK A PKE +PKE +P
Sbjct: 370 EPAPTTTKEPAPTTTKSA-PTTPKEPAP-----TTPKKPAPTTPKEPAPTTPKEPTPTTP 423
Query: 443 EAMVKASPKTSLEASMEASPKAKARDAPKK-SEMDKQALIPIAKKRLSSYTECYKWSSSP 501
+ P + + +PK A APKK + + P K + T ++P
Sbjct: 424 K-----EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478
Query: 502 ENACGLPSPISTNRQIQKNCPPS---PLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTV 558
+ P+P +T K+ P + P P +K +P T P + P T + + A +T
Sbjct: 479 KE----PAPTTT-----KSAPTTTKEPAPTTTKSAPTT--PKEPSP---TTTKEPAPTTP 524
Query: 559 KKKKETVSK 567
K+ T K
Sbjct: 525 KEPAPTTPK 533
Score = 52.4 bits (124), Expect = 2e-06
Identities = 81/420 (19%), Positives = 143/420 (34%), Gaps = 67/420 (15%)
Query: 216 TDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKC-TSDELRAVMF 274
T KE + + ++ + +T KE A P+ T T T P + T+ E A
Sbjct: 547 TPKEPAPTTTKKPA---PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603
Query: 275 PMSTMKIPPQTKVEESPLEKVETPPKASV-------------DAPPQVNVEVFCNTSMEA 321
P P+ +P E T PKA+ + P E T E
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 663
Query: 322 SPKAGVGMAPEVSTDSFPVVSV-----DVSPVVSTYDSEMSMD----ASPELSIEALPKV 372
+P G AP + P +++P + + + D +P+ + PK
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 723
Query: 373 DLETVPKVSIVASPEASL-----EAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPK 427
T PK +P+ + E P + P+ +G A PK
Sbjct: 724 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 783
Query: 428 ESVKGSPKESMEASPEAMVKASPKTSLEASMEAS-------------------PKAKARD 468
E+ +PKE +P+ +P+T + E S P+ A
Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 843
Query: 469 APKKSE-MDKQALIPIAKKRLSSYTECYKWS----------SSPENACGLP----SPIST 513
PK E K+ +P K ++ E + ++PE P +T
Sbjct: 844 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 903
Query: 514 NRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCE 573
+ ++ + ++ + Q + P+KI ++ T ++T KK T ++ N+ E
Sbjct: 904 TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT--KKTITTTEIMNKPE 961
Score = 37.7 bits (86), Expect = 0.047
Identities = 48/216 (22%), Positives = 81/216 (37%), Gaps = 38/216 (17%)
Query: 403 EVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPK-----------ESMEASPEAMVKASPK 451
EV +P S +APP A K + K SPK ES E + E V + +
Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124
Query: 452 TSLEASMEASPKA-----KARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACG 506
+S +S +S ++++ E+ K+ + KK + K E G
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184
Query: 507 LP----------------SPISTNRQIQKNCPPSPLPLI------SKQSPQTSFPYKIMP 544
L + +ST+ +I P +P P + SK++ T +
Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244
Query: 545 IQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHM 580
+ T + +ST K+K T +K T E S + +
Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 65.1 bits (157), Expect = 3e-10
Identities = 80/342 (23%), Positives = 117/342 (34%), Gaps = 33/342 (9%)
Query: 234 STDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLE 293
+T KE A P+ T T P + A +T K P T + +P
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP----TTTKEPAPTTTKSAPTT 548
Query: 294 KVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYD 353
E P + + P E T + +P AP + P + +P
Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608
Query: 354 SEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGS 413
+ +P+ + PK T P+ +PE PE PE PE
Sbjct: 609 AP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP 664
Query: 414 LEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPK----TSLEASMEASPKAKARDA 469
PK +A PKE +PKE +P+ +PK T+ + + + K A
Sbjct: 665 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 724
Query: 470 PKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLI 529
PKK + L P K +S T C P+P +T + P P P
Sbjct: 725 PKKPA--PKELAPTTTKEPTSTT------------CDKPAP-TTPKGTAPTTPKEPAPTT 769
Query: 530 SKQSPQTSFPYKIMPIQHTLSVQSASSTVKK--KKETVSKTT 569
K+ P + P P T + A +T KK KE TT
Sbjct: 770 PKE-PAPTTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTT 807
Score = 57.8 bits (138), Expect = 4e-08
Identities = 105/489 (21%), Positives = 176/489 (35%), Gaps = 72/489 (14%)
Query: 95 ERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRR 154
++KTK E + + + E +E ++ +K ++ K + R L+++
Sbjct: 142 KKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKN---SAANRELQKKL 198
Query: 155 LADDYQQKRWSW-----------GGSAMANSESKTANKRSASTEKLEQGTSALIRQM-PL 202
D ++ R GS + N + K +++T+ + TS I P+
Sbjct: 199 KVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 258
Query: 203 SSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLR 262
+ + T KE S ++N+ T E E T TN Q T
Sbjct: 259 NPR--PSLPPNSDTSKETSLTVNKE-------TTVETKE-----TTTTN--KQTSTDGKE 302
Query: 263 KCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEAS 322
K TS + + S + P +KV P K ET K P+ +
Sbjct: 303 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK--------EPTPTT 354
Query: 323 PKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSI 382
PK P+ T + ++ +P + + ++P E P E P
Sbjct: 355 PKEPASTTPKEPTPT----TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 410
Query: 383 VASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASP 442
+P + E P + A P E AP PK A PKE +PKE +P
Sbjct: 411 EPAPTTTKEPAPTTTKSA-PTTPKEPAP-----TTPKKPAPTTPKEPAPTTPKEPTPTTP 464
Query: 443 EAMVKASPKTSLEASMEASPKAKARDAPKK-SEMDKQALIPIAKKRLSSYTECYKWSSSP 501
+ P + + +PK A APKK + + P K + T ++P
Sbjct: 465 K-----EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 519
Query: 502 ENACGLPSPISTNRQIQKNCPPS---PLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTV 558
+ P+P +T K+ P + P P +K +P T P + P T + + A +T
Sbjct: 520 KE----PAPTTT-----KSAPTTTKEPAPTTTKSAPTT--PKEPSP---TTTKEPAPTTP 565
Query: 559 KKKKETVSK 567
K+ T K
Sbjct: 566 KEPAPTTPK 574
Score = 52.4 bits (124), Expect = 2e-06
Identities = 81/420 (19%), Positives = 143/420 (34%), Gaps = 67/420 (15%)
Query: 216 TDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKC-TSDELRAVMF 274
T KE + + ++ + +T KE A P+ T T T P + T+ E A
Sbjct: 588 TPKEPAPTTTKKPA---PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644
Query: 275 PMSTMKIPPQTKVEESPLEKVETPPKASV-------------DAPPQVNVEVFCNTSMEA 321
P P+ +P E T PKA+ + P E T E
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 704
Query: 322 SPKAGVGMAPEVSTDSFPVVSV-----DVSPVVSTYDSEMSMD----ASPELSIEALPKV 372
+P G AP + P +++P + + + D +P+ + PK
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 764
Query: 373 DLETVPKVSIVASPEASL-----EAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPK 427
T PK +P+ + E P + P+ +G A PK
Sbjct: 765 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 824
Query: 428 ESVKGSPKESMEASPEAMVKASPKTSLEASMEAS-------------------PKAKARD 468
E+ +PKE +P+ +P+T + E S P+ A
Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 884
Query: 469 APKKSE-MDKQALIPIAKKRLSSYTECYKWS----------SSPENACGLP----SPIST 513
PK E K+ +P K ++ E + ++PE P +T
Sbjct: 885 TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 944
Query: 514 NRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCE 573
+ ++ + ++ + Q + P+KI ++ T ++T KK T ++ N+ E
Sbjct: 945 TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT--KKTITTTEIMNKPE 1002
Score = 37.7 bits (86), Expect = 0.047
Identities = 48/216 (22%), Positives = 81/216 (37%), Gaps = 38/216 (17%)
Query: 403 EVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPK-----------ESMEASPEAMVKASPK 451
EV +P S +APP A K + K SPK ES E + E V + +
Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165
Query: 452 TSLEASMEASPKA-----KARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACG 506
+S +S +S ++++ E+ K+ + KK + K E G
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225
Query: 507 LP----------------SPISTNRQIQKNCPPSPLPLI------SKQSPQTSFPYKIMP 544
L + +ST+ +I P +P P + SK++ T +
Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 285
Query: 545 IQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHM 580
+ T + +ST K+K T +K T E S + +
Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 64.3 bits (155), Expect = 5e-10
Identities = 58/297 (19%), Positives = 93/297 (31%), Gaps = 9/297 (3%)
Query: 275 PMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVS 334
P +T PP T P+ TPP + +PP T+ + P +P +
Sbjct: 1425 PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPT--TTPSPPTT 1482
Query: 335 TDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPP 394
T S P + P +T + +P S LP + P + P + +PP
Sbjct: 1483 TPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542
Query: 395 EVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSL 454
+ P S P + +PP + P + P + + P P T
Sbjct: 1543 -TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPT-- 1599
Query: 455 EASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTN 514
+ + P P + PI ++ S P P P +T
Sbjct: 1600 --TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1657
Query: 515 RQIQKNCPPSPLPLISKQSPQT--SFPYKIMPIQHTLSVQSASSTVKKKKETVSKTT 569
P P+ + P T S P P T ++ + S T + TT
Sbjct: 1658 SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714
Score = 57.8 bits (138), Expect = 4e-08
Identities = 53/278 (19%), Positives = 89/278 (32%), Gaps = 23/278 (8%)
Query: 260 PLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSM 319
P+ T+ P +T PP T P TPP + +PP T+
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTT-TPSPPTTTTTTPPPTTTPSPP---------TTT 1506
Query: 320 EASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPK 379
+P A P +T S P + P +T + +P S LP + P
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566
Query: 380 VSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESME 439
+ P + +PP + + P ++ P + +PP + P + P +
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1626
Query: 440 ASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSS 499
P + P T+ SP P + +++ T
Sbjct: 1627 TPPTSTTTLPPTTT------PSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT------- 1673
Query: 500 SPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTS 537
+P SPI+T +P P + SP T+
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITT 1711
Score = 55.8 bits (133), Expect = 2e-07
Identities = 57/283 (20%), Positives = 88/283 (31%), Gaps = 19/283 (6%)
Query: 260 PLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSM 319
P+ KC + P +T PP T P +PP + PP
Sbjct: 1391 PMDKCITTPS-----PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTT-------- 1437
Query: 320 EASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPK 379
SP P +T P +S +P +T S + SP + + P T P
Sbjct: 1438 -PSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS-PPTTTTTTPP 1495
Query: 380 VSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESME 439
+ SP + P S LP + + P + PP + P + P +
Sbjct: 1496 PTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1555
Query: 440 ASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPI---AKKRLSSYTECYK 496
P P T+ +P P + P + ++ T
Sbjct: 1556 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT 1615
Query: 497 WSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFP 539
+ SP + P ST + PSP P + P T+ P
Sbjct: 1616 TTPSPPTTTPITPPTSTT-TLPPTTTPSPPPTTTTTPPPTTTP 1657
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/204 (19%), Positives = 68/204 (33%), Gaps = 7/204 (3%)
Query: 257 VTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKAS-------VDAPPQV 309
+T P T P +T PP T P TPP ++ +PP
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567
Query: 310 NVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEAL 369
T+ + P P ++T + P + P +T + SP +
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627
Query: 370 PKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKES 429
P T+P + + P + PP + + P + + P + PP + +P +
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITT 1687
Query: 430 VKGSPKESMEASPEAMVKASPKTS 453
P +M +SP T+
Sbjct: 1688 TPSPPTTTMTTPSPTTTPSSPITT 1711
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/189 (19%), Positives = 67/189 (35%), Gaps = 2/189 (1%)
Query: 275 PMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVS 334
P +T PP T P TPP + +PP T+ SP + P S
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP-SPPTTTPITPPTS 1631
Query: 335 TDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETV-PKVSIVASPEASLEAP 393
T + P + P +T + SP + P + T P + +SP + +P
Sbjct: 1632 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSP 1691
Query: 394 PEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTS 453
P ++ + ++P + P + P ++ + + P + P T+
Sbjct: 1692 PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT 1751
Query: 454 LEASMEASP 462
+ + +P
Sbjct: 1752 TSSPLTTTP 1760
Score = 40.8 bits (94), Expect = 0.006
Identities = 34/176 (19%), Positives = 60/176 (34%), Gaps = 2/176 (1%)
Query: 244 PRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASV 303
P +T T + P T+ P +T I P T P +PP +
Sbjct: 1589 PTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT 1648
Query: 304 DAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVS-TYDSEMSMDASP 362
PP T+ + P P +T S P+ + P + T S + +SP
Sbjct: 1649 TTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP 1708
Query: 363 ELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPP 418
+ + P ++ + +PP ++ LP + ++P + PP
Sbjct: 1709 ITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTT-SSPLTTTPLPP 1763
Score = 35.4 bits (80), Expect = 0.23
Identities = 26/141 (18%), Positives = 45/141 (31%)
Query: 257 VTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCN 316
+T P T P +T PP T P +PP + PP
Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPI 1685
Query: 317 TSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLET 376
T+ + P + +T S P+ + +T + +P + P T
Sbjct: 1686 TTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745
Query: 377 VPKVSIVASPEASLEAPPEVS 397
+ +SP + PP ++
Sbjct: 1746 TLPPTTTSSPLTTTPLPPSIT 1766
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 62.8 bits (151), Expect = 1e-09
Identities = 115/586 (19%), Positives = 210/586 (35%), Gaps = 80/586 (13%)
Query: 74 ERREEKRRQQDANK---ETQLLEKERKTKLQYEKQMEERQRKLK-ERKEKEEQRRIAAEE 129
ERR + RQ A K +Q E+E + R LK E +E+EE+ +E
Sbjct: 225 ERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDE 284
Query: 130 KRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKL 189
+ DE QK + IL E + + M + KT RS E L
Sbjct: 285 EEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEE-------MMDERPKT---RSQEQEVL 334
Query: 190 EQGTSALIRQMPLSSAGLQNSVAKRKTDKE--RSSSLNRRDSNLHSS---TDKEQAERKP 244
E+G R ++ +A+++ +KE +S L + + SS +K ++ P
Sbjct: 335 ERGG----RFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPP 390
Query: 245 RVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKV-EESPLEKVE------- 296
R+T V +P + + +E + PP ++ E +E +E
Sbjct: 391 RLT-EDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVL 449
Query: 297 ---TPPKASVDA----PPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVV 349
+PP D Q V++ S +SP +P V+ + +
Sbjct: 450 IQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTL 509
Query: 350 STYDSEMSMDASPELSIEALP-KVDLETVPK---VSIVASPEASLEAPPEVSLEALPEVS 405
+ Y ++ ++ + S + LP K++ + K + P + S LP
Sbjct: 510 ADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPSHR 569
Query: 406 VEAAPEGSLEAPPKGSAEVAPKES-------------VKGSPKESMEASPEAMVKASPKT 452
++ + + S S+ + S ++ ++ +A A + PK
Sbjct: 570 LKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKM 629
Query: 453 SLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPIS 512
++ E+ ++++R S K +++ +SYTE SS E A
Sbjct: 630 GSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVA-------- 681
Query: 513 TNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRC 572
PP P + + +TS + + +SA V ++ + + +C
Sbjct: 682 --------TPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKC 733
Query: 573 EALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEE 618
EA EE+ + +E T L E R+ EKEE
Sbjct: 734 EA--------EEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEE 771
Score = 40.8 bits (94), Expect = 0.006
Identities = 38/185 (20%), Positives = 82/185 (44%), Gaps = 13/185 (7%)
Query: 74 ERREEKR--RQQDANKETQLLEKER-KTKLQYEK-QMEERQRKLKERKEKEEQRRIAAEE 129
E+RE++R R+Q A +E ++ +ER +++ ++++ ++ E R +++ + R ++E
Sbjct: 1134 EQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKE 1193
Query: 130 KRHQKDEAQKEKFTAILYRTLERRRLA---------DDYQQKRWSWGGSAMANSESKTAN 180
K+ +K E +E+ A L L R+ A D Q + + A K
Sbjct: 1194 KKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRK 1253
Query: 181 KRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQA 240
++ +K + + R L + +R ++ER +R D + D+E+
Sbjct: 1254 EQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERG 1313
Query: 241 ERKPR 245
+ R
Sbjct: 1314 RERDR 1318
Score = 40.8 bits (94), Expect = 0.006
Identities = 20/89 (22%), Positives = 50/89 (56%), Gaps = 3/89 (3%)
Query: 56 PVIDGSMLKNDIKQRLARERREEKRRQQDANKETQL---LEKERKTKLQYEKQMEERQRK 112
P+ D +++ + ++ + RE++R++Q+ ++ + E+ER +L+ EK+ E + +
Sbjct: 1228 PLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRER 1287
Query: 113 LKERKEKEEQRRIAAEEKRHQKDEAQKEK 141
+ER+ + E+ R + R + E +E+
Sbjct: 1288 DRERERERERDRGDRDRDRERDRERGRER 1316
Score = 38.5 bits (88), Expect = 0.028
Identities = 35/184 (19%), Positives = 79/184 (42%), Gaps = 17/184 (9%)
Query: 67 IKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIA 126
++++ A RE +RR++ ++ +K R+ + + R+++ + KEK+ +++
Sbjct: 1142 VREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEK 1201
Query: 127 AEEKRHQK---DEAQKEKFTAILY-----------RTLERRRLADDYQQKRWSWGGSAMA 172
A+E+ K D +K K +Y + ER A + +++R
Sbjct: 1202 AQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQK 1261
Query: 173 NSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAK---RKTDKERSSSLNRRDS 229
E + +R+ E+ ++ + R ++ + R+ D+ER +RRD+
Sbjct: 1262 EREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDT 1321
Query: 230 NLHS 233
HS
Sbjct: 1322 KRHS 1325
Score = 38.5 bits (88), Expect = 0.028
Identities = 36/171 (21%), Positives = 70/171 (40%), Gaps = 22/171 (12%)
Query: 607 RRLAREQREKEEEERQREEMQQ--RVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNET--- 661
R + R +R + E E R+++++ R +S+D ++ E + K+ Q+
Sbjct: 1151 REMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKL 1210
Query: 662 -----KKKKG-----WLDQEDQEAPLQKGDAKIKAQEEADKRK-------KEHERIMLQN 704
+K K WL D + ++ + +A+E +RK KE E+ +
Sbjct: 1211 LDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERE 1270
Query: 705 LQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDS 755
+LER+KR E +R R+ + + D + E E +D+
Sbjct: 1271 RNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDT 1321
Score = 33.9 bits (76), Expect = 0.68
Identities = 24/96 (25%), Positives = 52/96 (54%), Gaps = 17/96 (17%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E + +EQ E+E++ER++E ++R ++ + +E + +H + +D +++ E ++
Sbjct: 1247 EREKRRKEQEEEEQKEREKEAERER----NRQLERE----KRREHSRERDRERERERERD 1298
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKR-KKEHER 699
+G D+ D+E ++G E D+R K H R
Sbjct: 1299 RGDRDR-DRERDRERG-------RERDRRDTKRHSR 1326
Score = 33.1 bits (74), Expect = 1.2
Identities = 36/149 (24%), Positives = 71/149 (47%), Gaps = 16/149 (10%)
Query: 583 EESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKD--MAKE 640
EE ++ + + A + TE E+ E+EEEE EE +KS++ + KE
Sbjct: 248 EEEDQETPSRNLRVRADRNLKTE----EEEEEEEEEEEDDEEEEGDDEGQKSREAPILKE 303
Query: 641 AVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADK----RKKE 696
+ E+ ++K + +E K + ++QE L++G ++QEEA K R+++
Sbjct: 304 -FKEEGEEIPRVKPEEMMDERPKTR----SQEQEV-LERGGRFTRSQEEARKSHLARQQQ 357
Query: 697 HERIMLQNLQERLERKKRIEEIMKRTRKT 725
+ + + E ER+ + + +K K+
Sbjct: 358 EKEMKTTSPLEEEEREIKSSQGLKEKSKS 386
Score = 32.7 bits (73), Expect = 1.5
Identities = 57/269 (21%), Positives = 110/269 (40%), Gaps = 28/269 (10%)
Query: 609 LAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWL 668
LAR+Q+EKE + E ++R IK S+ + KE + L +D ++ + +
Sbjct: 352 LARQQQEKEMKTTSPLEEEEREIKSSQGL-KEKSKSPSPPRL-TEDRKKASLVALPEQTA 409
Query: 669 DQEDQEAPLQKGDA-------KIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKR 721
+E+ PL +A ++ ++EE + + +++Q + R + +
Sbjct: 410 SEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQH 469
Query: 722 TRKTDVNASKVTETSSHDIYEEAEADNEES-----------DKDSLNEMFPSAILNGTGS 770
T + S ++ S AE EES D + ++ P + +
Sbjct: 470 TVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPL 529
Query: 771 PTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRP 830
P K + AK +T + + S +KE + + L + R K D+S SR
Sbjct: 530 PLKIE-ELALAKGITEECL---KQPSLEQKEGRRASHTLLPSHRLKQSADSS----SSRS 581
Query: 831 SSKRMTSHTTKTRKADETNTTSRSSAQTK 859
SS +S +++R D + + S S ++K
Sbjct: 582 SSSSSSSSRSRSRSPDSSGSRSHSPLRSK 610
Score = 32.3 bits (72), Expect = 2.0
Identities = 38/177 (21%), Positives = 70/177 (39%), Gaps = 30/177 (16%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKG 666
R L E+ E+EEEE + ++ ++ + +D +GQ+ E K
Sbjct: 265 RNLKTEEEEEEEEEEEEDDEEE----------------EGDD-----EGQKSREAPILKE 303
Query: 667 WLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTD 726
+ +E +E P ++K +E D+R K R Q + ER R R +E +++
Sbjct: 304 F-KEEGEEIP------RVKPEEMMDERPK--TRSQEQEVLERGGRFTRSQEEARKSHLAR 354
Query: 727 VNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNNAKK 783
K +T+S EE E + + K+ P + + +P A +
Sbjct: 355 QQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASE 411
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 60.5 bits (145), Expect = 7e-09
Identities = 82/380 (21%), Positives = 156/380 (41%), Gaps = 41/380 (10%)
Query: 398 LEALPEVSVEAAPEGSLEAPPKGSAEVAPKESV--KGSPKESMEASPEAMVKASPKTSLE 455
LE L V V + PP+ + VA E + + S + + ++P
Sbjct: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
Query: 456 ASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNR 515
AS +P A ++A K + D P + +R SY + ++ +
Sbjct: 419 ASSPETPSAGQQEA-KTDQADGPREPPQSARRKRSYKQAVSELDEEQHL--------EDE 469
Query: 516 QIQ---KNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKK---KKETVSKTT 569
++Q P SP P P +F + + Q ++ SA +V K K+ T +
Sbjct: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
Query: 570 NRCEALSQRHMIYEESGNKSTAGIMNA------------EAATKILTELRRL--AREQRE 615
+C + + E K A + E K LR++ ARE+ E
Sbjct: 530 PKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVE 589
Query: 616 --KEEEERQREEMQQRVIKKSKDMAKEAVGGQ-------AEDHLKLKDGQQQNETKKKKG 666
KEE+++Q E+ ++ +K++ +E + + A+ +++ ++Q E ++
Sbjct: 590 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 649
Query: 667 WLDQEDQEAPLQKGDAKIKAQEEADKRK-KEHERIMLQNLQERLERKKRIEEIMKRTRKT 725
WL QE++E Q+ K K +E+ RK E +R+ Q QER E+++R +E ++ R+
Sbjct: 650 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE 709
Query: 726 DVNASKVTETSSHDIYEEAE 745
+ + + + E E
Sbjct: 710 QERREQERQLAEQERRREQE 729
Score = 49.7 bits (117), Expect = 1e-05
Identities = 41/170 (24%), Positives = 87/170 (51%), Gaps = 14/170 (8%)
Query: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMN-AEAATKILTELRRLAREQREKE 617
K+ ++ ++ + E + + E++ K+ A M EA K E RRL Q+E
Sbjct: 597 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE-- 654
Query: 618 EEERQREEMQQRVIKKSKDMAKEA-----VGGQAEDHLKLKDGQQQNETKKKKGWLDQED 672
EEER+ +E+ Q+ ++ ++ ++A + Q E + ++ ++Q ++++ ++ +
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714
Query: 673 QEAPL-----QKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEE 717
QE L ++ +++A+ E +R+K R+ + LQ LE KK+ EE
Sbjct: 715 QERQLAEQERRREQERLQAERELQEREKA-LRLQKEQLQRELEEKKKKEE 763
Score = 48.5 bits (114), Expect = 3e-05
Identities = 35/159 (22%), Positives = 77/159 (48%), Gaps = 4/159 (2%)
Query: 556 STVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQRE 615
+ KK +E ++ EA R + EE + + + + LR+ A +R
Sbjct: 627 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ--ERLRKAAEAKRL 684
Query: 616 KEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEA 675
E+ E++R E ++R ++ + +E + E L ++ +++ E + + L + ++
Sbjct: 685 AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 744
Query: 676 PLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKR 714
LQK +++ + E K+K+E +R+ + LQE E+K +
Sbjct: 745 RLQK--EQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
Score = 48.1 bits (113), Expect = 3e-05
Identities = 52/239 (21%), Positives = 102/239 (42%), Gaps = 25/239 (10%)
Query: 16 LRELRARMVAAANEI--AKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLAR 73
L E +A+ AAA ++ + RRKQ+ R R + + ++ Q+
Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEAR--------RLRWLQQEEEERRHQELLQKKKE 669
Query: 74 ERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQ 133
E +E R+ +A + + E+ER+ + + E++ E++R+ +ER+E+E Q AE++R +
Sbjct: 670 EEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ---LAEQERRR 726
Query: 134 KDE--------AQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSAS 185
+ E ++EK + L+R ++++ + + K A + + +
Sbjct: 727 EQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGA 786
Query: 186 TEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKP 244
++ L Q P ++ R K + D N STD E RKP
Sbjct: 787 SKALNVTVDV---QSPACTSYQMTPQGHRAPPKINPDNYG-MDLNSDDSTDDEAHPRKP 841
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/192 (20%), Positives = 84/192 (43%), Gaps = 22/192 (11%)
Query: 73 RERREEKRRQQDANK-ETQLLEKERKTKLQYEK-QMEERQRK----------LKERKEKE 120
R+R E RR+++A + Q +E++++ +L+ K + EER RK +KE K+K+
Sbjct: 539 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 598
Query: 121 EQRRIA--------AEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMA 172
+++ A A+E+R +++A+K+ + RR+ ++ ++ RW
Sbjct: 599 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 658
Query: 173 NSESKTANKRSASTEKLEQGTSA--LIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSN 230
+ K+ E+L + A L Q + +R+ + R ++
Sbjct: 659 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ 718
Query: 231 LHSSTDKEQAER 242
L + + ER
Sbjct: 719 LAEQERRREQER 730
Score = 39.7 bits (91), Expect = 0.012
Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 25/185 (13%)
Query: 78 EKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR-------RIAAEEK 130
EK RQ+ N L KE +L+ +K E+++R+L+E K K E+R R E+
Sbjct: 536 EKERQRLEN----LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQM 591
Query: 131 RHQKDEAQKEKFTAILYRT--LERRRLADDYQQKRWSWGG----SAMANSESKTANKRSA 184
+ +K + ++KF I +T + RLA++ +K+ + A E + R
Sbjct: 592 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 651
Query: 185 STEKLEQGTSALIR------QMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKE 238
E+ E+ L++ Q L A +A+++ + R RR+ +E
Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ--ERREQERREQERRE 709
Query: 239 QAERK 243
Q R+
Sbjct: 710 QERRE 714
Score = 38.5 bits (88), Expect = 0.028
Identities = 26/92 (28%), Positives = 50/92 (54%), Gaps = 8/92 (8%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E R +E+RE+E E++R+ +Q ++ + + E + E L+L+ Q Q E ++K
Sbjct: 699 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 758
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKE 696
K +E+Q+ ++ + QEE +K+ KE
Sbjct: 759 K---KKEEQQRLAER-----QLQEEQEKKAKE 782
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 58.9 bits (141), Expect = 2e-08
Identities = 83/379 (21%), Positives = 143/379 (37%), Gaps = 31/379 (8%)
Query: 69 QRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERK-EKEEQRRIAA 127
+ L E +E + +E + +E + + Q E ++ E Q +E + E E+ +
Sbjct: 1923 EALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEV 1982
Query: 128 E-EKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSAST 186
E E + + EAQ E + A++ Q S G A SE + A + T
Sbjct: 1983 EVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPE-SDGVEAQPKSEGEEAQEVEGET 2041
Query: 187 EKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRV 246
+K E S G++ A+ + +E + + H ++ A+
Sbjct: 2042 QKTEGDAQP-------ESDGVEAPEAEEEA-QEAEGEVQEAEGEAHPESEDVDAQE---A 2090
Query: 247 TGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAP 306
G + V P + + + + P+T+ E P + P+A +A
Sbjct: 2091 EGEAQPESEGVEAPEAEGEAQKAEGIE--------APETEGEAQPESEGIEAPEAEGEAQ 2142
Query: 307 PQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSI 366
P+ + EA P++ A E ++ P + +P E +A PE
Sbjct: 2143 PESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAP-------EAEGEAQPESEG 2195
Query: 367 EALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPE--GSLEAPPKGSAEV 424
P+ + E P++ V +PEA EA PE PE EA PE G + KGS +V
Sbjct: 2196 IEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQV 2255
Query: 425 APKESVKGSPKESMEASPE 443
+ + ES PE
Sbjct: 2256 SLGDGQSEEASESSSPVPE 2274
Score = 53.1 bits (126), Expect = 1e-06
Identities = 87/411 (21%), Positives = 151/411 (36%), Gaps = 46/411 (11%)
Query: 74 ERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQ 133
E E ++ Q + + LE E + + + E + + + E + Q E +
Sbjct: 1907 EAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEA 1966
Query: 134 KDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGT 193
++EAQ E +E + + Q+ G A SE A + ++ E+
Sbjct: 1967 EEEAQPES------EDVEALEVEVETQEAE----GEAQPESEDVEAPEAEGEMQEAEEEA 2016
Query: 194 SALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYV 253
S G++ A+ K++ E + + T K + + +P GV
Sbjct: 2017 QP-------ESDGVE---AQPKSEGEEAQEVE-------GETQKTEGDAQPESDGVEAPE 2059
Query: 254 MQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEV 313
+ E P S + + E P + P+A +A +E
Sbjct: 2060 AEEEAQEAEG-EVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEA 2118
Query: 314 FCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVD 373
T EA P++ APE ++ P S V D+E +A PE + +
Sbjct: 2119 -PETEGEAQPESEGIEAPEAEGEAQPE-----SEGVEAQDAEG--EAQPESEGIEAQEAE 2170
Query: 374 LETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGS 433
E P++ V +PEA EA PE +EA PE EA P+ AP+ +
Sbjct: 2171 EEAQPELEGVEAPEAEGEAQPESE-------GIEA-PEAEGEAQPELEGVEAPEAEEEAQ 2222
Query: 434 PKESMEASPEAMVKASPKTSLEASME--ASPKAKARDAPKKSEMDKQALIP 482
P+ +PEA +A P++ E E SP+ D + + + +P
Sbjct: 2223 PEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVP 2273
Score = 52.0 bits (123), Expect = 2e-06
Identities = 79/328 (24%), Positives = 128/328 (39%), Gaps = 28/328 (8%)
Query: 153 RRLADDYQQKRWSWGGSAMANS-ESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSV 211
+RL D K G AMA E KT N +++ +L + +S G
Sbjct: 1750 QRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQ---EGEGISERGETGGQ 1806
Query: 212 AKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRA 271
D + + D + S E E P G + V P + + E
Sbjct: 1807 GSGHEDNLQGEAAAGGDQDPGQSDGAEGIEA-PEAEGEAQPESEGVEAPEAEGDAQEAEG 1865
Query: 272 VMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAP 331
+ P+++ E+P + E P++ P+ EV P++ AP
Sbjct: 1866 --------EAQPESEDVEAPEAEGEAQPESEDVETPEAEWEV--------QPESEGAEAP 1909
Query: 332 EVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLE 391
E ++ P + D S A + + EA + + +T P+ ++ S EA E
Sbjct: 1910 EAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEE 1969
Query: 392 APPE-VSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKES-MEASPEA-MVKA 448
A PE +EAL EV VE E EA P+ AP+ +G +E+ EA PE+ V+A
Sbjct: 1970 AQPESEDVEAL-EVEVE-TQEAEGEAQPESEDVEAPE--AEGEMQEAEEEAQPESDGVEA 2025
Query: 449 SPKTSLEASMEASPKAKARDAPKKSEMD 476
PK+ E + E + + + + E D
Sbjct: 2026 QPKSEGEEAQEVEGETQKTEGDAQPESD 2053
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/398 (19%), Positives = 154/398 (38%), Gaps = 42/398 (10%)
Query: 366 IEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVA 425
IEA P+ + E P+ V +PEA +A E EA PE APE EA P+
Sbjct: 1835 IEA-PEAEGEAQPESEGVEAPEAEGDAQ-EAEGEAQPESEDVEAPEAEGEAQPESEDVET 1892
Query: 426 PKESVKGSPKESMEASPEAMVKASPKT----SLEASMEASPKAKARDAPKKSEMDKQALI 481
P+ + P+ +PEA +A P+T +LE E P+++ +A + E ++A
Sbjct: 1893 PEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEA-- 1950
Query: 482 PIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSP--LPLISKQSPQTSFP 539
+ + PE S + +++ ++ P + + +
Sbjct: 1951 --------------EGQTQPE------SEVIESQEAEEEAQPESEDVEALEVEVETQEAE 1990
Query: 540 YKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAA 599
+ P + A +++ +E ++ EA + E + E
Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSE---GEEAQEVEGETQKTEGD 2047
Query: 600 TKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDM-AKEAVGGQAEDHLKLKDGQQQ 658
+ ++ + E +E E + +E + +S+D+ A+EA G + ++ + +
Sbjct: 2048 AQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAE 2107
Query: 659 NETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQ-------ERLER 711
E +K +G ++ + E Q I+A E + + E E + Q+ + E +E
Sbjct: 2108 GEAQKAEG-IEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEA 2166
Query: 712 KKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNE 749
++ EE + ++ + E EA+ E
Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE 2204
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 58.5 bits (140), Expect = 3e-08
Identities = 41/180 (22%), Positives = 87/180 (48%), Gaps = 24/180 (13%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
K + ++R R+R EK R+++ K+ + K+R+ + E++ +ER+++ KER+EKE ++
Sbjct: 37 KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96
Query: 124 RIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRS 183
R ++KR +K ++E+ + ER+ + +Q+R + + +R
Sbjct: 97 RKKEKKKRERKQRGRRER-----KKKKERKERERENKQRR------ERKRKKRRKKKRRK 145
Query: 184 ASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERK 243
+ E+G R+ ++K ++E+ NR++ KE+ ERK
Sbjct: 146 ERKREKERGKRERKRK------------KRKKEEREKKRERNRKERKKERER-KERRERK 192
Score = 55.1 bits (131), Expect = 3e-07
Identities = 38/152 (25%), Positives = 73/152 (48%), Gaps = 5/152 (3%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKG 666
R+ R +REK + ER++E ++R K+ K K G + E K K+ ++Q + +++K
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERE--RKRKEREKQRKERREK- 92
Query: 667 WLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTD 726
++ ++ +K + K + + E K+K+ ER + +RKKR ++ ++ RK +
Sbjct: 93 --ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 727 VNASKVTETSSHDIYEEAEADNEESDKDSLNE 758
K EE E E + K+ E
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKE 182
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/112 (26%), Positives = 63/112 (56%), Gaps = 2/112 (1%)
Query: 32 KERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARER--REEKRRQQDANKET 89
KERRK+ + R K + + + KQR R+R R +K+R+++ +E
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 90 QLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEK 141
+ ++ERK K + +++ E+++ + ++ ++KE +R+ E K+ +K E +K+K
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Score = 51.6 bits (122), Expect = 3e-06
Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 8/99 (8%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQY--------EKQMEERQRKLKE 115
K + KQR RER+++K R++ + Q E++RK + + EK+ +R+RK K+
Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162
Query: 116 RKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRR 154
RK++E +++ K +K+ +KE+ R ERR+
Sbjct: 163 RKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Score = 50.8 bits (120), Expect = 5e-06
Identities = 36/168 (21%), Positives = 77/168 (45%)
Query: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEE 618
K+K+E + ++ E G + E K E R R++ +K+
Sbjct: 45 KRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKR 104
Query: 619 EERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQ 678
E +QR +++ K+ K+ +E + K + +++ E K++K +E + +
Sbjct: 105 ERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRK 164
Query: 679 KGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTD 726
K + + K + +RKKE ER + ++ ++++R ++ K+ RKTD
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/135 (25%), Positives = 74/135 (54%), Gaps = 9/135 (6%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E R R +R+KE+++R+R++ +R KK K+ + + ++ + ++ +++ KKK
Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKE-----RERENKQRRERKRKKRRKKK 142
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEH--ERIMLQNLQERLERKK--RIEEIMK 720
+ + ++E ++ K + +EE +K+++ + ER + +ER ERKK + E K
Sbjct: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
Query: 721 RTRKTDVNASKVTET 735
+ RK D + T++
Sbjct: 203 KERKKDRKTDRQTDS 217
Score = 47.0 bits (110), Expect = 8e-05
Identities = 36/181 (19%), Positives = 79/181 (43%), Gaps = 2/181 (1%)
Query: 17 RELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERR 76
RE R E +ER K++ R R + + + K+R R++
Sbjct: 41 REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100
Query: 77 EEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDE 136
++KR ++ + + +KERK + + KQ ER+RK +R++K+ ++ E++R +++
Sbjct: 101 KKKRERKQRGRRERKKKKERKERERENKQRRERKRK--KRRKKKRRKERKREKERGKRER 158
Query: 137 AQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSAL 196
+K++ + ER R +++R + + K K ++ T +
Sbjct: 159 KRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Query: 197 I 197
+
Sbjct: 219 V 219
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/129 (21%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 611 REQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETK-----KKK 665
RE+ +KE+++R++ E + +K K+ K+ + ++ K K +++ E K ++K
Sbjct: 56 RERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERK 115
Query: 666 GWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKT 725
+++++E ++ + + + KR+KE +R + +ER +K++ EE K+ +
Sbjct: 116 KKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175
Query: 726 DVNASKVTE 734
K E
Sbjct: 176 RKERKKERE 184
Score = 38.5 bits (88), Expect = 0.028
Identities = 32/157 (20%), Positives = 63/157 (40%), Gaps = 23/157 (14%)
Query: 89 TQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYR 148
TQ + +K + + EK+ ER+++ K + K+ E+K+ +K E KE+
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKK-------EKKKRKKRERGKER------- 75
Query: 149 TLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQ 208
ER+R + Q+K E + K E+ ++G ++ +
Sbjct: 76 --ERKRKEREKQRKE-------RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Query: 209 NSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPR 245
N + + K+R R++ K + +RK R
Sbjct: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR 163
Score = 31.2 bits (69), Expect = 4.4
Identities = 29/132 (21%), Positives = 61/132 (46%), Gaps = 13/132 (9%)
Query: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEE 618
K+KK+ K R E ++ E NK E K + +R +REKE
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQ-----RRERKRKKRRKKKRRKERKREKER 153
Query: 619 EERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQ 678
+R+R+ +++ K+ ++ +E ++ K ++ +++ E KK++ +E ++ +
Sbjct: 154 GKRERKRKKRK--KEEREKKRER---NRKERKKERERKERRERKKER---KKERRKKKER 205
Query: 679 KGDAKIKAQEEA 690
K D K Q ++
Sbjct: 206 KKDRKTDRQTDS 217
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 58.2 bits (139), Expect = 3e-08
Identities = 128/585 (21%), Positives = 219/585 (37%), Gaps = 86/585 (14%)
Query: 172 ANSESKTANKRSASTEKLE-QGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSN 230
A ++ +++ +S E+ E QG A +P GL A K + SS + D
Sbjct: 78 AKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDD- 136
Query: 231 LHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEES 290
D+E +++P GV P + +SD + S + P K + +
Sbjct: 137 -----DEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSD---SDSDSSSEDEPPKNQKPKIT 188
Query: 291 PLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVS 350
P+ KA APP+ A+PK G A S+ S
Sbjct: 189 PVTV-----KAQTKAPPK---------PARAAPKIANGKAASSSSSS------------- 221
Query: 351 TYDSEMSMDASPELSIEALPKVDLETVPKVSIVA-SPEASLEAPPEVSLEALPEVSVEAA 409
S S D S E A PK +TVPK +VA +P + P S + S E
Sbjct: 222 --SSSSSSDDSEEEKAAATPK---KTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEE 276
Query: 410 PEGSLEAPPKGSAEVAPKESVKGSPKESMEASP--EAMVKASPKTSLEASMEASPKAKAR 467
+ G P S PK+S+ P +A+ K P S E S + S +
Sbjct: 277 EQKKPMKNKPGPYSSVPPPSAP-PPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEE 335
Query: 468 DA--PKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCP--- 522
+ P K+ + K P K+ + + S S E+ P T + N P
Sbjct: 336 EKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKN-SSNKPAVT 394
Query: 523 ---PSPLPLISKQSPQTSFPYKIMPIQHTLSV---QSASSTVKKKKETVSKTTNRCEALS 576
P+ P + + P K++ + S +S+SS +K K+ V+ T + A +
Sbjct: 395 TKSPAVKPAAAPKQP-VGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKA 453
Query: 577 QRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKD 636
+ +++ S ++++++ + E+ EK + +++ Q+ +
Sbjct: 454 ALSLPAKQAPQGSRDSSSDSDSSS---------SEEEEEKTSKSAVKKKPQKVAGGAAPS 504
Query: 637 MAKEAVGGQAE-DHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQE-EADKRK 694
A G+AE + D + E +K KG Q AP G + + AQ +A K
Sbjct: 505 KPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQ-APKANGTSALTAQNGKAAKNS 563
Query: 695 KEHERIMLQNLQERLERKKRIEEIMKRT----RKTDVNASKVTET 735
+E E E KK+ ++ ++ ++ A+K ET
Sbjct: 564 EEEE-----------EEKKKAAVVVSKSGSLKKRKQNEAAKEAET 597
Score = 49.7 bits (117), Expect = 1e-05
Identities = 125/615 (20%), Positives = 224/615 (36%), Gaps = 70/615 (11%)
Query: 70 RLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEE 129
+ A + E ++ ++ + + +K++ + + Q + + K+ K + ++E+
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED 177
Query: 130 KRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKL 189
+ + QK K T + T++ + A + + A S S +++ S+S +
Sbjct: 178 ---EPPKNQKPKITPV---TVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSE 231
Query: 190 EQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGV 249
E+ +A ++ + + K T R SS S+ SS+D+E+ ++KP +
Sbjct: 232 EEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSS-----SSEDSSSDEEEEQKKP----M 282
Query: 250 TNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVE-ESPLEKVETPPKASVDA--- 305
N Y +VP + S PP+ VE + P+E E S +
Sbjct: 283 KNKPGPYSSVPPPSAPPPK-------KSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEE 335
Query: 306 ---PPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMS---MD 359
PP V T + KA + +DS P +T +S
Sbjct: 336 EKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTT 395
Query: 360 ASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPK 419
SP + A PK + K+ + +S E E S + E + + +A K
Sbjct: 396 KSPAVKPAAAPKQPVGGGQKLLTRKADSSSSE---EESSSSEEEKTKKMVATTKPKATAK 452
Query: 420 GSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQA 479
+ + K++ +GS S ++ + + KTS A + K AP K K
Sbjct: 453 AALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAK-- 510
Query: 480 LIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFP 539
K + S SS E L S Q K S L + ++ + S
Sbjct: 511 -----KGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEE 565
Query: 540 YKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAA 599
+ + + V + S K+K+ +K Q I ++ N
Sbjct: 566 EEEEKKKAAVVVSKSGSLKKRKQNEAAKEAE----TPQAKKIKLQTPN------------ 609
Query: 600 TKILTELRRLAREQREKEEEERQRE---EMQQRVIKKSKDMAKEAVGG---QAEDHLKLK 653
T +R E+R R RE E+ RV S D + A G +A LK
Sbjct: 610 ----TFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFT 665
Query: 654 DGQ--QQNETKKKKG 666
G+ + +TKKK+G
Sbjct: 666 KGKSFRHEKTKKKRG 680
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 57.8 bits (138), Expect = 4e-08
Identities = 75/377 (19%), Positives = 154/377 (40%), Gaps = 39/377 (10%)
Query: 398 LEALPEVSVEAAPEGSLEAPPKGSAEVAPKESV--KGSPKESMEASPEAMVKASPKTSLE 455
LE L V V + PP+ + VA E + + S + + ++P
Sbjct: 359 LERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPA 418
Query: 456 ASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNR 515
AS +P A ++A K + D P + +R SY + ++ +
Sbjct: 419 ASSPETPSAGQQEA-KTDQADGPREPPQSARRKRSYKQAVSELDEEQHL--------EDE 469
Query: 516 QIQ---KNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTV-------------- 558
++Q P SP P P +F + + Q ++ SA +V
Sbjct: 470 ELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMD 529
Query: 559 --KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREK 616
+K+++ + + EA R EE + + + ++ L+ R ++ K
Sbjct: 530 PKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-KLKREERLRKVLQARERVEQMK 588
Query: 617 EEEERQREEMQQRVIKKSKDMAKEAVGGQ-------AEDHLKLKDGQQQNETKKKKGWLD 669
EE+++Q E+ ++ +K++ +E + + A+ +++ ++Q E ++ WL
Sbjct: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
Query: 670 QEDQEAPLQKGDAKIKAQEEADKRK-KEHERIMLQNLQERLERKKRIEEIMKRTRKTDVN 728
QE++E Q+ K K +E+ RK E +R+ Q QER E+++R +E ++ R+
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQER 708
Query: 729 ASKVTETSSHDIYEEAE 745
+ + + + E E
Sbjct: 709 REQERQLAEQERRREQE 725
Score = 49.7 bits (117), Expect = 1e-05
Identities = 41/170 (24%), Positives = 87/170 (51%), Gaps = 14/170 (8%)
Query: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMN-AEAATKILTELRRLAREQREKE 617
K+ ++ ++ + E + + E++ K+ A M EA K E RRL Q+E
Sbjct: 593 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE-- 650
Query: 618 EEERQREEMQQRVIKKSKDMAKEA-----VGGQAEDHLKLKDGQQQNETKKKKGWLDQED 672
EEER+ +E+ Q+ ++ ++ ++A + Q E + ++ ++Q ++++ ++ +
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710
Query: 673 QEAPL-----QKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEE 717
QE L ++ +++A+ E +R+K R+ + LQ LE KK+ EE
Sbjct: 711 QERQLAEQERRREQERLQAERELQEREKA-LRLQKEQLQRELEEKKKKEE 759
Score = 48.5 bits (114), Expect = 3e-05
Identities = 35/159 (22%), Positives = 77/159 (48%), Gaps = 4/159 (2%)
Query: 556 STVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQRE 615
+ KK +E ++ EA R + EE + + + + LR+ A +R
Sbjct: 623 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ--ERLRKAAEAKRL 680
Query: 616 KEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEA 675
E+ E++R E ++R ++ + +E + E L ++ +++ E + + L + ++
Sbjct: 681 AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 740
Query: 676 PLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKR 714
LQK +++ + E K+K+E +R+ + LQE E+K +
Sbjct: 741 RLQK--EQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Score = 48.1 bits (113), Expect = 3e-05
Identities = 52/239 (21%), Positives = 102/239 (42%), Gaps = 25/239 (10%)
Query: 16 LRELRARMVAAANEI--AKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLAR 73
L E +A+ AAA ++ + RRKQ+ R R + + ++ Q+
Sbjct: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEAR--------RLRWLQQEEEERRHQELLQKKKE 665
Query: 74 ERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQ 133
E +E R+ +A + + E+ER+ + + E++ E++R+ +ER+E+E Q AE++R +
Sbjct: 666 EEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ---LAEQERRR 722
Query: 134 KDE--------AQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSAS 185
+ E ++EK + L+R ++++ + + K A + + +
Sbjct: 723 EQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGA 782
Query: 186 TEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKP 244
++ L Q P ++ R K + D N STD E RKP
Sbjct: 783 SKALNVTVDV---QSPACTSYQMTPQGHRAPPKINPDNYG-MDLNSDDSTDDEAHPRKP 837
Score = 43.9 bits (102), Expect = 7e-04
Identities = 33/189 (17%), Positives = 87/189 (46%), Gaps = 9/189 (4%)
Query: 61 SMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKL-----QYEKQMEERQRKLKE 115
++ + + ++L R++ EE +R++ +E +L +ER K+ + E+ EE+++++++
Sbjct: 540 NLRRKEEAEQLRRQKVEEDKRRR--LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQ 597
Query: 116 RKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSE 175
+ + +++ A+E+R +++A+K+ + RR+ ++ ++ RW +
Sbjct: 598 KFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQ 657
Query: 176 SKTANKRSASTEKLEQGTSA--LIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHS 233
K+ E+L + A L Q + +R+ + R ++ L
Sbjct: 658 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 717
Query: 234 STDKEQAER 242
+ + ER
Sbjct: 718 QERRREQER 726
Score = 42.4 bits (98), Expect = 0.002
Identities = 53/214 (24%), Positives = 97/214 (45%), Gaps = 25/214 (11%)
Query: 45 THSSNIRSTFKPVID-GSMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYE 103
T +S RS K I + L+ D K++ R+R E RR+++A E+ R+ K++ +
Sbjct: 507 TPTSAPRSVMKSFIKRNTPLRMDPKEK-ERQRLENLRRKEEA-------EQLRRQKVEED 558
Query: 104 KQ--MEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRT--LERRRLADDY 159
K+ +EE + K +ER K Q R E+ + +K + ++KF I +T + RLA++
Sbjct: 559 KRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEK 618
Query: 160 QQKRWSWGG----SAMANSESKTANKRSASTEKLEQGTSALIR------QMPLSSAGLQN 209
+K+ + A E + R E+ E+ L++ Q L A
Sbjct: 619 AKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAK 678
Query: 210 SVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERK 243
+A+++ + R RR+ +EQ R+
Sbjct: 679 RLAEQREQERREQ--ERREQERREQERREQERRE 710
Score = 38.5 bits (88), Expect = 0.028
Identities = 26/92 (28%), Positives = 50/92 (54%), Gaps = 8/92 (8%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E R +E+RE+E E++R+ +Q ++ + + E + E L+L+ Q Q E ++K
Sbjct: 695 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKE 696
K +E+Q+ ++ + QEE +K+ KE
Sbjct: 755 K---KKEEQQRLAER-----QLQEEQEKKAKE 778
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 57.4 bits (137), Expect = 6e-08
Identities = 39/185 (21%), Positives = 91/185 (49%), Gaps = 5/185 (2%)
Query: 62 MLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEE 121
+LK + ++RL +ERRE++ +++ + QLL++E + + Q K+ E++ +L++R ++EE
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR--EQEERLEQRLKREE 606
Query: 122 QRRIAAEEKRHQ---KDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKT 178
R+ EE+R Q ++E ++E+ +L + R ++++ + E +
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 179 ANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKE 238
++ E E+ + + A + K + S + R S ++S K+
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 239 QAERK 243
+ +R+
Sbjct: 727 EGQRR 731
Score = 57.0 bits (136), Expect = 7e-08
Identities = 44/188 (23%), Positives = 88/188 (46%), Gaps = 19/188 (10%)
Query: 67 IKQRLARERREEKRRQQDANKETQLLEKERKTKL-----QYEKQMEERQRKLKERKEKEE 121
++QRL RE EE+R Q+ A +E + + K+++ Q E + + RQ K+ R K+E
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE 727
Query: 122 QRRIAAEEKRHQKDEAQKEKFTAILYRTLER-RRLADDYQQKR---WSWGGSAMANSESK 177
+R +R +++E ++ + + + ++ ER R + +Q+R W W + +
Sbjct: 728 GQR-----RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Query: 178 TANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDK 237
+ R E+ E+ A RQ Q + + + ++R R+ L ++
Sbjct: 783 RLSARPPLREQRERQLRAEERQQ-----REQRFLPEEEEKEQRRRQRREREKELQFLEEE 837
Query: 238 EQAERKPR 245
EQ +R+ R
Sbjct: 838 EQLQRRER 845
Score = 54.3 bits (129), Expect = 5e-07
Identities = 44/177 (24%), Positives = 85/177 (48%), Gaps = 8/177 (4%)
Query: 75 RREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQ-----RKLKERKEKEEQRRIAAEE 129
+ EE +RQ++ +E + L K + +L+ E+Q EE+Q R+ + R+++EE+RR EE
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320
Query: 130 KRHQKD--EAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTE 187
+R Q++ E Q+E+ L R E RR +++ + + + ++ E
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Query: 188 KLEQGTSALIRQMPL-SSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERK 243
+ + L R+ L L+ R+ + R RR+ L ++E+ E+K
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
Score = 53.9 bits (128), Expect = 6e-07
Identities = 44/182 (24%), Positives = 82/182 (45%), Gaps = 20/182 (10%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEK-ERKTKLQYEKQMEERQRKLKERKEKEEQRRIA 126
+Q L RER+EE+++QQ +E QL K E + + Q E++ E+++R+ ++ + +E+Q R
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 127 AEEKRHQ--KDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSA 184
EE+R Q + E ++E+ L R E R ++++ E + ++
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ-------QLRREQQLRREQQL 395
Query: 185 STEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKP 244
E+ + L R+ L +R+ R L R EQ R+
Sbjct: 396 RREQQLRREQQLRREQQL----------RREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 245 RV 246
R+
Sbjct: 446 RL 447
Score = 53.1 bits (126), Expect = 1e-06
Identities = 49/205 (23%), Positives = 93/205 (45%), Gaps = 38/205 (18%)
Query: 68 KQRLARERREEKRRQQDAN----------KETQLL--------EKERKTKLQYEKQMEER 109
+++L RE RE++RRQ+ KE QLL +ER+ K + E+++++
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999
Query: 110 QRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRL---------ADDYQ 160
+ +L R+E+E++RR E + +KDE Q+E+ +L E+RRL ++ Q
Sbjct: 1000 EEQLL-REEREKRRRQEWERQYRKKDELQQEE-EQLLREEREKRRLQERERQYREEEELQ 1057
Query: 161 QKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKER 220
Q+ G + ++ E+L+Q L+R+ P +R+ ++ER
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP---------EKRRRQERER 1108
Query: 221 SSSLNRRDSNLHSSTDKEQAERKPR 245
+E+ E++ R
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRR 1133
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/225 (24%), Positives = 98/225 (43%), Gaps = 26/225 (11%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKE--EQR-R 124
+QRL RE EE+RRQQ E Q E+ R+ +L+ E+Q E R+++LK +E+E EQR +
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQ--EERRQQQLRREQQ-ERREQRLKREEEEERLEQRLK 673
Query: 125 IAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSA 184
EE+R +++ A++E+ A R R+ + +W A A + R
Sbjct: 674 REHEEERREQELAEEEQEQA-------RERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 185 STEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKP 244
++ Q R+ + A R+ +E RRD +++ +
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE----QRRDFTWQWQAEEKSERGRQ 782
Query: 245 RVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEE 289
R++ PLR+ +LRA + P+ + +E
Sbjct: 783 RLS---------ARPPLREQRERQLRAEERQQREQRFLPEEEEKE 818
Score = 50.4 bits (119), Expect = 7e-06
Identities = 43/186 (23%), Positives = 87/186 (46%), Gaps = 19/186 (10%)
Query: 68 KQRLARERREEK-RRQQDANKETQLLEKERKTKLQY----EKQMEERQRKLKER-KEKEE 121
++R +ERRE++ RR+Q+ +E +L +E + +LQ E+Q+ Q + +E+ ++EE
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 122 QRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANK 181
++R+ E + + Q+E+ +L R ERR+ +Q+ E + +
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE---------RLEQRLKRE 605
Query: 182 RSASTEKLEQGTSALIRQMPLSSAGLQ----NSVAKRKTDKERSSSLNRRDSNLHSSTDK 237
E+ E+ L R+ P Q +R+ + R RR+ L ++
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 238 EQAERK 243
E+ E++
Sbjct: 666 ERLEQR 671
Score = 50.4 bits (119), Expect = 7e-06
Identities = 42/184 (22%), Positives = 83/184 (45%), Gaps = 17/184 (9%)
Query: 68 KQRLA-----RERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEE- 121
+QRL+ RE+RE + R ++ + Q E + K Q +Q ER+++L+ +E+E+
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Query: 122 QRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANK 181
QRR A++ + ++D Q+++ ERRR + + ++W W T
Sbjct: 841 QRRERAQQLQEEEDGLQEDQ---------ERRRSQEQRRDQKWRWQLEEERKRRRHTLYA 891
Query: 182 RSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAE 241
+ A E+L + L Q + +R+ ++ER + +E+ E
Sbjct: 892 KPALQEQLRKEQQLL--QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 242 RKPR 245
++ R
Sbjct: 950 KRRR 953
Score = 49.7 bits (117), Expect = 1e-05
Identities = 37/143 (25%), Positives = 77/143 (53%), Gaps = 8/143 (5%)
Query: 605 ELRRLAREQREKEEE--ERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETK 662
+LRR R+++ +EEE ++REE Q R + + +E Q + +L+ Q+ + +
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822
Query: 663 KKKGWLDQEDQEAPL-QKGDAKIKAQEE---ADKRKKEHERIMLQNLQERLERKKR--IE 716
++ L E+QE L Q+ D + +A+E+ +K ++E + + + Q+R + ++R E
Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Query: 717 EIMKRTRKTDVNASKVTETSSHD 739
E ++R +K + +V E S +
Sbjct: 1883 EHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/117 (27%), Positives = 64/117 (54%), Gaps = 16/117 (13%)
Query: 63 LKNDIKQRLARERREEKRRQQDANK----------ETQLLEKERKTKLQYEKQMEERQRK 112
L + ++ L RE RE++RRQ+ + E QLL +ER+ + + E++ + R+ K
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
Query: 113 LKERKEKE------EQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
++KE++ E+RR EK+++++E +++ +L E+RR + +Q R
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Score = 48.9 bits (115), Expect = 2e-05
Identities = 35/150 (23%), Positives = 73/150 (48%), Gaps = 10/150 (6%)
Query: 605 ELRRLAREQREK----EEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNE 660
+LR R+QRE+ EEEE+++ Q+R +K +E E+ L+ ++ QQ +
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE------EEQLQRRERAQQLQ 850
Query: 661 TKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMK 720
++ DQE + + Q+ D K + Q E +++++ H LQE+L +++++ + +
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 721 RTRKTDVNASKVTETSSHDIYEEAEADNEE 750
+ + + + EE + EE
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEE 940
Score = 48.5 bits (114), Expect = 3e-05
Identities = 52/296 (17%), Positives = 124/296 (41%), Gaps = 28/296 (9%)
Query: 558 VKKKKETVSKTTNRCEALSQRHMIYEESGNK---STAGIMNAEAATKILTE---LRRLAR 611
+++++E + R + + ++E G K + E K L E LR R
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 612 EQREKEEEERQREEMQQRVIKKSKDM----AKEAVGGQAEDHLKLKDGQQQNETKKKKG- 666
EQ+ +++ +R+ E +Q++ ++ +D ++ V Q + L++ QQ + + +K
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 667 -----WLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIM-- 719
++E+Q+ Q+ D K +E+ +R++ + Q L+ + +K +EE
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 720 --KRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMP 777
++ ++ + + + D + +++ L + L+ KF++
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLE 1584
Query: 778 FNNAKKMTHKLVFLED--------GTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQE 825
++ + F+ED G Q+R+E F D + +++ + QE
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Score = 48.1 bits (113), Expect = 3e-05
Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 14/151 (9%)
Query: 63 LKNDIKQRLARERR-----------EEKRRQQDANKETQLLEKERKTKLQYEKQMEERQR 111
L+ D ++R ++E+R E KRR+ + L E+ RK + +++ EE QR
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 112 KLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERR---RLADDYQQKRWSWGG 168
+ +E++ ++EQ R EE++ Q++E Q + R ER R QQK G
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 169 SAMANSESKTANKRSASTEKLEQGTSALIRQ 199
+ K+ E+L+Q L+R+
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Score = 47.8 bits (112), Expect = 5e-05
Identities = 42/195 (21%), Positives = 88/195 (45%), Gaps = 20/195 (10%)
Query: 67 IKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKE-RKEKEE---- 121
+K+ ER E++RR+Q ++ + +ER KL+ E++ E+++R+ ++ R+E+EE
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 122 -----------QRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSA 170
Q+R+ +E++ ++ E ++E+ L + E +RL + +++R
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQ----LLKREEEKRLEQERREQRLKREQEE 573
Query: 171 MANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSN 230
+ K +R K EQ R L+ + + K RR
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 231 LHSSTDKEQAERKPR 245
L S +E+ +++ R
Sbjct: 634 LKSEEQEERRQQQLR 648
Score = 47.4 bits (111), Expect = 6e-05
Identities = 33/155 (21%), Positives = 82/155 (52%), Gaps = 12/155 (7%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
+LRR E+RE+ + ++ EE Q+ ++ + + +E + + L ++ +++ E +++
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE--ERREQLLKREEEKRLEQERR 563
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKR--KKEHERIMLQNLQ----ERLERKKRIEEI 718
+ L +E +E + D +K +EE ++ K+E E + Q L+ ERLE+++R E+
Sbjct: 564 EQRLKREQEE----RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 719 MKRTRKTDVNASKVTETSSHDIYEEAEADNEESDK 753
+KR + ++ ++ + + + E+ ++
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Score = 47.0 bits (110), Expect = 8e-05
Identities = 51/176 (28%), Positives = 79/176 (44%), Gaps = 23/176 (13%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKER-KTKLQYEKQMEERQRKLKERKEKEEQRRIA 126
+QRL RE+ EE+R +ET+ E+ER K +L+ +++ E R+R LK +EE+RR
Sbjct: 444 EQRLKREQ-EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL---EEEERREQ 499
Query: 127 AEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSAST 186
E + Q Q+E+ L R E RL QQ+ S E + +
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERL----QQRLRSEQQLRREQEERREQLLKREEE 555
Query: 187 EKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAER 242
++LEQ R+ L KR+ ++ R L R + +EQ ER
Sbjct: 556 KRLEQER----REQRL----------KREQEERRDQLLKREEERRQQRLKREQEER 597
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 18/194 (9%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRK----LKERKEKEEQR 123
+ R E ++RRQ+ +E +L E E +++ Q + +RQR+ ++R+E +E+
Sbjct: 125 RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE 184
Query: 124 RIAAEE------KRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESK 177
AEE K H+ +E E+ RR+ ++ QQ+R E K
Sbjct: 185 ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK 244
Query: 178 TANKRSA----STEKLEQGTSALIRQMPLSSAGL----QNSVAKRKTDKERSSSLNRRDS 229
KR EKL++ R++ L + + + + ++E+ RR+
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ 304
Query: 230 NLHSSTDKEQAERK 243
L ++E+ E++
Sbjct: 305 QLRRKQEEERREQQ 318
Score = 46.6 bits (109), Expect = 1e-04
Identities = 40/187 (21%), Positives = 88/187 (47%), Gaps = 14/187 (7%)
Query: 68 KQRLARE----RREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
+Q+L RE R ++ RR+Q +E QL ++ + + + + + E R+++LK +E+EE+R
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK--REQEERR 455
Query: 124 RIAAEEKRHQKDEAQKEKFTAILYRTLERR----RLADDYQQKRWSWGGSAMANSESKTA 179
E+ ++ E ++ K + ERR +L ++ ++++ + + +
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 180 NKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQ 239
+R E+ E+ L + L + K ++E+ RR+ L +EQ
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL----KREQ 571
Query: 240 AERKPRV 246
ER+ ++
Sbjct: 572 EERRDQL 578
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/121 (26%), Positives = 68/121 (56%), Gaps = 8/121 (6%)
Query: 603 LTELRRLAREQREKEEEERQ----REEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQ 658
L ELRR RE+++++ ERQ +EE ++ K+ + KE Q E+ + ++ Q++
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 659 NETKKK--KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIE 716
E +K + L +E QE Q+ +++ +++ ++++E R + +E+ ER+++ E
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQ--QRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 717 E 717
E
Sbjct: 333 E 333
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/182 (23%), Positives = 85/182 (46%), Gaps = 25/182 (13%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKE---RKTKLQYEKQM-EERQRKLKERKEKEEQR 123
+Q+L RE+ EE+RR+Q +E QL ++ R+ +L+ E+Q+ E+Q + +++ +E+Q
Sbjct: 361 EQQLRREQ-EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 124 RIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRS 183
R + +R Q++E ++K + R + Q++R W KR
Sbjct: 420 RREQQLRREQEEERHEQK-----HEQERREQRLKREQEERRDW-------------LKRE 461
Query: 184 ASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERK 243
TE+ EQ +Q+ + + ++ER RR+ L ++ + +R
Sbjct: 462 EETERHEQERRK--QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 244 PR 245
R
Sbjct: 520 KR 521
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/186 (23%), Positives = 79/186 (42%), Gaps = 12/186 (6%)
Query: 68 KQRLARERREEKRRQQDANK----ETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
+Q+L + RE++ RQ K E QL +ER K + E+Q RQ + ++ E+E+Q
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Query: 124 RIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRS 183
R K ++++ +E+ L+R R+ ++ QQ R E ++
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
Query: 184 ASTEKLEQGTSALIRQMPL----SSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQ 239
E+ EQ RQ Q +R+ D++R R + L +++Q
Sbjct: 1516 KFLEE-EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKF---REEEQLRQEREEQQ 1571
Query: 240 AERKPR 245
R+ R
Sbjct: 1572 LSRQER 1577
Score = 45.8 bits (107), Expect = 2e-04
Identities = 25/81 (30%), Positives = 52/81 (64%), Gaps = 6/81 (7%)
Query: 64 KNDIKQRLARERREEKRRQQDANK----ETQLLEKERKTKLQYEKQMEERQRKLKERKEK 119
K+ +++L RE REEKRR+Q+ ++ E QLL++ + L+ +Q +R+ + +E + +
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR--RQERDRKFREEELRHQ 1370
Query: 120 EEQRRIAAEEKRHQKDEAQKE 140
E+ R+ EE+R ++ E +++
Sbjct: 1371 EQGRKFLEEEQRLRRQERERK 1391
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/279 (17%), Positives = 118/279 (42%), Gaps = 26/279 (9%)
Query: 593 IMNAEAATKILTELRRLAREQREK-----EEEERQREEMQQRVIKKSKDMAKEAVGGQAE 647
+ + E K L E ++L R+QR++ E++ R++E QQR + + +E Q
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
Query: 648 DHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQE-------EADKRKKEHERI 700
+ +L ++ + + ++ + +++QE + + +++ QE E D++ +E E++
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Query: 701 MLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMF 760
+ + +++L R++R + ++ + + + + HD D + +++ L +
Sbjct: 1628 LQEREEQQLHRQERDRKFLE--EEPQLRRQEREQQLRHD------RDRKFREEEQLLQEG 1679
Query: 761 PSAILNGTGSPTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKD 820
L KF+ ++ + FL++ R+E + F ++ ++
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR------EEEQLRQ 1733
Query: 821 TSIQEVVSRPSSKRMTSHTTKTRKADETNTTSRSSAQTK 859
+ QE + R R + R E R K
Sbjct: 1734 ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 15/165 (9%)
Query: 599 ATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQ 658
A L E R ++ ++EEEE QREE ++R ++ + +E E+ L+ ++ Q
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE------EEQLQQEEEQLL 944
Query: 659 NETKKKKGWLDQEDQ---EAPLQKGDAKIKAQEEADKRKKEHERIML--QNLQERLERKK 713
E ++K+ ++E Q + LQ+ + ++ +E +R++E E+ + LQ+ E+
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 714 RIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNE 758
R E +R ++ + K E EE + EE +K L E
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQ----EEEQLLREEREKRRLQE 1045
Score = 45.4 bits (106), Expect = 2e-04
Identities = 30/98 (30%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Query: 74 ERREEKRRQQDANKETQLLEKERKTK---LQYEKQMEERQRKLKERKE-----KEEQRRI 125
E++E KRR + + +E QLL +ER+ K + +++ E ++ L+ER+E +E R+
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
Query: 126 AAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
EE RHQ+ + + L R R+ + QQ R
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Score = 45.4 bits (106), Expect = 2e-04
Identities = 54/283 (19%), Positives = 117/283 (41%), Gaps = 24/283 (8%)
Query: 606 LRRLAREQREKEEEERQRE------EMQQRVIKKSKD--MAKEAVGGQAEDHLKLKDGQQ 657
LRR R+++ +EEE R +E E +QR+ ++ ++ KE E L+ ++ +Q
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE------EQQLRCQEREQ 1406
Query: 658 QNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEE 717
Q + + + +E+Q+ Q+ D K + +E+ +R++ + + + Q R ER ++ E
Sbjct: 1407 QLRQDRDRKF-REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1465
Query: 718 IMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMP 777
+ ++ + E + EE + +E D+ F L KF
Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR-----KFREQELRSQEPERKFLEE 1520
Query: 778 FNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDL-KNFRQKSM--KDTSIQEVVSRPSSKR 834
+ + FL++ R+E D + FR++ ++ Q++ + ++
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 835 MTSHTTKTRKADETNTTSRSSAQ-TKSEGFHDILPKSSDTFRQ 876
K R+ ++ Q + EG + + FR+
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE 1623
Score = 45.1 bits (105), Expect = 3e-04
Identities = 51/225 (22%), Positives = 105/225 (46%), Gaps = 22/225 (9%)
Query: 558 VKKKKETVSKTTNRCEALSQRHMIY--EESGNKSTAGIMNAEAATKILTELRRLAREQRE 615
+++++E + + L +R Y EE + ++ E T+ EL R R++ E
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 616 KEEEERQ--REEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQ-----QQNETKKKKGWL 668
++EE Q REE ++R ++ + +E Q E+ L++ + Q+ E + ++
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 669 DQEDQEAPLQKGDAKIKAQE------EADKRKKEHERIMLQNLQERL---ERKKRIEEIM 719
Q+++E L++ K + QE E ++ ++E E+++ + ++R ER+ R EE +
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Query: 720 KRTRK----TDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMF 760
+R ++ D + + E A DN+ K NE F
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Score = 45.1 bits (105), Expect = 3e-04
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQM-----------EERQRKLKE- 115
+Q L R+ REE++ +Q+ +E QL +ER K+ E+Q+ +ER RK +E
Sbjct: 1718 RQELERKFREEEQLRQETEQE-QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776
Query: 116 ---RKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMA 172
R+E+EEQ+ + E R ++E Q L + E ++L + ++ W +
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQ-------LRQEREEQQLRPQQRDGKYRWEEEQLQ 1829
Query: 173 NSESKTANKRSASTE-KLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNL 231
E + ++ + + E+ + + Q KR+ ++ER R+ ++
Sbjct: 1830 LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER----KLREEHI 1885
Query: 232 HSSTDKEQAERK 243
+EQ R+
Sbjct: 1886 RRQQKEEQRHRQ 1897
Score = 44.7 bits (104), Expect = 4e-04
Identities = 35/138 (25%), Positives = 72/138 (52%), Gaps = 10/138 (7%)
Query: 32 KERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERREEKRRQQDANKETQL 91
+E+R++ R ++ + ++ K +++R R+ REE+ QQ+ E QL
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER-ERQYREEEELQQE---EEQL 1063
Query: 92 LEKERKTKL------QYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAI 145
L +ER+T+ QY K+ E +Q + + +E+ E+RR E++ +++E +++ +
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 146 LYRTLERRRLADDYQQKR 163
L E+RR + +Q R
Sbjct: 1124 LREEREKRRRQELERQYR 1141
Score = 44.3 bits (103), Expect = 5e-04
Identities = 38/193 (19%), Positives = 88/193 (45%), Gaps = 11/193 (5%)
Query: 62 MLKNDIKQRLARERREEKRRQQDANKETQLL-----EKERKTKL--QYEKQMEERQRKLK 114
+L+ + ++R +ER + R +++ +E + L EK R+ +L QY ++ E +Q + +
Sbjct: 1093 LLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Query: 115 ERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANS 174
+E+ E+RR E++++++E +++ +L E+RR + Q +
Sbjct: 1153 LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQ 1212
Query: 175 ESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRD----SN 230
+ ++RS + E +R + G +N ++ D + +++D
Sbjct: 1213 RYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLG 1272
Query: 231 LHSSTDKEQAERK 243
D+EQ R+
Sbjct: 1273 EQQERDREQERRR 1285
Score = 43.9 bits (102), Expect = 7e-04
Identities = 30/124 (24%), Positives = 73/124 (58%), Gaps = 10/124 (8%)
Query: 605 ELRRLAREQ----REKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNE 660
+LR+L R++ R++EE+++QR +Q++ +K ++ +E Q E + + +QQ E
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ---QEERREQQERREQQEE 333
Query: 661 TKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMK 720
++++ +QE++ + + + + +E+ +R++E ER + Q R E++ R E+ ++
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLRREQEEER---REQQLRREQQLRREQQLR 390
Query: 721 RTRK 724
R ++
Sbjct: 391 REQQ 394
Score = 43.9 bits (102), Expect = 7e-04
Identities = 32/163 (19%), Positives = 85/163 (52%), Gaps = 21/163 (12%)
Query: 605 ELRRLAREQRE----KEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNE 660
+LRR E+RE +EEE+R +E +++ +K+ ++ ++ + + E+ + + ++Q E
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 661 ------TKKKKGWLDQED--------QEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQ 706
+++ L+QE+ +E ++ +K++E+ ++R+++ R + +
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Query: 707 ERLER---KKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEA 746
+RL+R ++R+E+ +KR + + ++ E E ++
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Score = 43.9 bits (102), Expect = 7e-04
Identities = 41/188 (21%), Positives = 85/188 (45%), Gaps = 7/188 (3%)
Query: 571 RCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRV 630
R E +R +E K E + E RRL +R+ EEE ++E +Q +
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 631 IKKSKDMAKEAVGGQ--AEDHLKLKDGQQQNETKKKKGWLDQEDQ---EAPLQKGDAKIK 685
++ + ++ + Q E+ L+ ++ Q E +K+ ++E Q E LQ+ + ++
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL 1124
Query: 686 AQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAE 745
+E +R++E ER + + + E ++ + E ++ R+ ++ E EE +
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ--EEEQ 1182
Query: 746 ADNEESDK 753
EE +K
Sbjct: 1183 LLREEQEK 1190
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/196 (21%), Positives = 85/196 (43%), Gaps = 32/196 (16%)
Query: 59 DGSMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKT--------KLQYEKQMEERQ 110
D L+ L R+ REEK++Q+ ++ E+E K + + EK EE
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 111 RKLKERKEKEEQ-RRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGS 169
++ +E +E+EEQ R++ +E R ++ E ++ +++RL + Q +R
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQ-----------QQQRLRREQQLRR------ 308
Query: 170 AMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDS 229
+ +R E+ EQ +Q+ + +R+ ++E RR+
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE------RREQ 362
Query: 230 NLHSSTDKEQAERKPR 245
L ++E+ E++ R
Sbjct: 363 QLRREQEEERREQQLR 378
Score = 43.5 bits (101), Expect = 9e-04
Identities = 23/120 (19%), Positives = 71/120 (59%), Gaps = 5/120 (4%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E +L + +R++ ERQ EE QQ+ +++ + + ++ + E + ++ Q++ E +++
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRK 724
+ +Q+ + ++ + +++ ++E ++R+++ R + +ER E++ R E+ ++R ++
Sbjct: 334 R--REQQLRREQEERREQQLRREQEEERREQQLRR---EQEEERREQQLRREQQLRREQQ 388
Score = 43.5 bits (101), Expect = 9e-04
Identities = 32/138 (23%), Positives = 71/138 (51%), Gaps = 11/138 (7%)
Query: 64 KNDIKQRLARERREEK--RRQQDANKETQLLEKERKTKLQYE-------KQMEERQRKLK 114
+ + ++RL + R E+ RR+Q+ +E QLL++E + +L+ E ++ EER+ +L
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERRE-QLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 115 ERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRL-ADDYQQKRWSWGGSAMAN 173
+R+E+ Q+R+ E++ + ++E+ + +RL ++ +++R +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 174 SESKTANKRSASTEKLEQ 191
E + R E+ EQ
Sbjct: 640 EERRQQQLRREQQERREQ 657
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/188 (21%), Positives = 82/188 (43%), Gaps = 31/188 (16%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQM---EERQRKLKERKEKE 120
+ +++ ER E+K Q+ + + ++ER+ L+ E++ E+ +RK + ++++E
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 121 EQRR-----IAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSE 175
E+RR + EE+R Q++ +++ L R E RR + + KR E
Sbjct: 482 EERRERWLKLEEEERREQQERREQQ-----LRREQEERR---EQRLKR---------QEE 524
Query: 176 SKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSST 235
+ +R S ++L + Q+ L+ KR + R L R
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQL------LKREEEKRLEQERREQRLKREQEERRDQL 578
Query: 236 DKEQAERK 243
K + ER+
Sbjct: 579 LKREEERR 586
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/177 (22%), Positives = 89/177 (50%), Gaps = 17/177 (9%)
Query: 560 KKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELR--RLAREQREKE 617
K++E + R + Q EE + ++ E ++ E R RL REQ E+
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQ----LLKREEEKRLEQERREQRLKREQEERR 575
Query: 618 EE--ERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQN------ETKKKKGWLD 669
++ +R+ E QQR+ ++ ++ ++ + + + L+ ++ ++Q E ++++ L
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635
Query: 670 QEDQEAPLQKGDAKIKAQ--EEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRK 724
E+QE Q+ + + + E+ KR++E ER+ Q L+ E ++R +E+ + ++
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLE-QRLKREHEEERREQELAEEEQE 691
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/187 (20%), Positives = 87/187 (46%), Gaps = 13/187 (6%)
Query: 63 LKNDIKQRLARERREEKRRQQDANK----ETQLLEKERKTKLQYEKQMEERQRKLKERKE 118
L++ + ++ R+R +E+RR Q ++ E QL +E+K + +++ +E ++ L+E +E
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE 1326
Query: 119 KEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKT 178
E++RR + K ++++ +E+ L R ER R + + + G + +
Sbjct: 1327 -EKRRRQETDRKFREEEQLLQEREEQPL-RRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384
Query: 179 ANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKE 238
+R K EQ R+ L + + +E L+R++ + +++
Sbjct: 1385 RQERERKFLKEEQQLRCQEREQQLRQ-------DRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 239 QAERKPR 245
Q R+ R
Sbjct: 1438 QVRRQER 1444
Score = 43.1 bits (100), Expect = 0.001
Identities = 40/191 (20%), Positives = 83/191 (43%), Gaps = 23/191 (12%)
Query: 75 RREEKRRQQDANKETQLLEKERKTKLQYEK-QMEERQRKLKE------RKEKEEQRRIAA 127
R EE+ RQ+ ++ E++RK +L+ +K + +E++RK E R+E ++Q R
Sbjct: 1558 REEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
Query: 128 EEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTE 187
+ K + ++ +E+ L+R R+ ++ Q R + + + K +
Sbjct: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR---KFREEEQ 1674
Query: 188 KLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERS----------SSLNRR---DSNLHSS 234
L++G +R+ + R+ ++ER L R+ + L
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE 1734
Query: 235 TDKEQAERKPR 245
T++EQ R+ R
Sbjct: 1735 TEQEQLRRQER 1745
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/126 (18%), Positives = 75/126 (59%), Gaps = 6/126 (4%)
Query: 605 ELRRLAREQREKEEEER-QREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKK 663
+LRR R+++ +EEE++ +R+E +++ +++ + + ++ + + + +L+ +Q + ++
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
Query: 664 KKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERL-----ERKKRIEEI 718
++ + ++E + + + ++E D++ +E E++ + +++L +RK R EE
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
Query: 719 MKRTRK 724
+++ R+
Sbjct: 1803 LRQERE 1808
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/171 (20%), Positives = 82/171 (47%), Gaps = 25/171 (14%)
Query: 608 RLAREQREKEEEE--RQREEMQQRVIKKSKDMAKEAVGGQA------EDHLKLK------ 653
RL + R++ +EE RQR+E Q+R +++++ ++ G E+ L+ +
Sbjct: 160 RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELR 219
Query: 654 -----DGQQQNETKKKKGWLDQED-----QEAPLQKGDAKIKAQEEADKRKKEHERIMLQ 703
+ QQQ ++ + + ++E+ +E L+K + K++ +E +R+ + E L+
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 704 NLQ-ERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDK 753
L+ + L R+++ EE ++ + + + E + EE E ++
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/94 (30%), Positives = 53/94 (56%), Gaps = 10/94 (10%)
Query: 68 KQRLARERREEKRRQQDANKETQLL--EKERKTKLQYEKQMEERQRKLKE-----RKEKE 120
+Q L R+ R+E+ QQ+ E QLL E E++ + + E+Q E + +E R+E+E
Sbjct: 1073 RQELERQYRKEEELQQE---EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE 1129
Query: 121 EQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRR 154
++RR E + +++E Q+E+ + +RRR
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 19/151 (12%)
Query: 63 LKNDIKQRLARERREEKRRQQDANK---ETQLLEKERKTKLQYEKQM-----------EE 108
L + R RE ++ RRQ+ K E Q L +ER K + E+Q+ +E
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Query: 109 RQRKLKERKE----KEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRR-LADDYQQKR 163
R RK E ++ +E R+ +E R Q+ E + + L+R +R+ L ++ Q +R
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 164 WSWGGSAMANSESKTANKRSASTEKLEQGTS 194
G + + K + E+ EQ S
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLS 1573
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/156 (22%), Positives = 72/156 (46%), Gaps = 12/156 (7%)
Query: 12 GSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRL 71
G LR+ R R ++ +ER +Q + + K + + L+ +++
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR--------KFLEEEPQLRRQEREQQ 1660
Query: 72 ARERREEKRRQQDA----NKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAA 127
R R+ K R+++ +E QL +ER K + E+Q RQ + ++ ++E+Q R
Sbjct: 1661 LRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQE 1720
Query: 128 EEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
E++ +++E +++ R ER R + +Q R
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/186 (23%), Positives = 87/186 (46%), Gaps = 17/186 (9%)
Query: 68 KQRLARE----RREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
+Q+L RE R ++ RR+Q +E QL +++ + Q ++ ++ +R+ + R+E+EE+R
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Query: 124 RIAAEEKRHQKDEAQKEKFTAILYRT-LERRRLADDYQQKRWSWGGSAMANSESKTANKR 182
E+K Q+ Q+ K R L+R + ++Q+R + + + +R
Sbjct: 434 H---EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK---QQLKRDQEEERRER 487
Query: 183 SASTEKLEQGTSALIRQMPL--SSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQA 240
E+ E+ R+ L + KR+ ++ER R + L +EQ
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR----REQE 543
Query: 241 ERKPRV 246
ER+ ++
Sbjct: 544 ERREQL 549
Score = 41.2 bits (95), Expect = 0.004
Identities = 24/118 (20%), Positives = 67/118 (56%), Gaps = 4/118 (3%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKG 666
++L REQ+ + E++ +RE+ +R + ++ +E + + + ++ + + E ++++
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEER--HEQKHEQERREQRLKREQEERRD 456
Query: 667 WLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRK 724
WL +E++ + + K Q + D+ ++ ER + +ER E+++R E+ ++R ++
Sbjct: 457 WLKREEETE--RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
Score = 40.8 bits (94), Expect = 0.006
Identities = 29/135 (21%), Positives = 64/135 (47%), Gaps = 2/135 (1%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKG 666
+RL REQ E+ E+ +REE+++ ++ ++ + + E +L ++Q E ++++
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL 647
Query: 667 WLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTD 726
+Q+++ K + + + E+ KR+ E ER + +E E+ + E I R K
Sbjct: 648 RREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR--ERIKSRIPKWQ 705
Query: 727 VNASKVTETSSHDIY 741
+ +Y
Sbjct: 706 WQLESEADARQSKVY 720
Score = 40.8 bits (94), Expect = 0.006
Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 9/99 (9%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEK---EEQRR 124
+Q+L R+ RE K Q++ Q LE++ + + Q ++ E+ Q + +ER K EEQ R
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 125 IAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
EE++ ++ E ++ +R E+ R + QQ R
Sbjct: 1757 PEREEQQLRRQERDRK------FREEEQLRQEREEQQLR 1789
Score = 40.4 bits (93), Expect = 0.007
Identities = 34/180 (18%), Positives = 80/180 (44%), Gaps = 8/180 (4%)
Query: 69 QRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKE-----RKEKEEQR 123
+ L R+R+E + R++ +E QL + ++ + + R+R+L E R+EK++QR
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230
Query: 124 RIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRS 183
R + +++E + K +L + E+ + + +Q+ + E + +
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 184 ASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERK 243
E+ +Q L R+ L + +++ +E+ +++ +EQ ER+
Sbjct: 291 QEEEQQQQ---RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
Score = 40.0 bits (92), Expect = 0.009
Identities = 38/180 (21%), Positives = 82/180 (45%), Gaps = 11/180 (6%)
Query: 577 QRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQRE--KEEEERQREEMQQRVIKKS 634
+R EE + ++ E + EL R RE+ E +EEE+ REE ++R ++
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166
Query: 635 KDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRK 694
+ +E Q E+ L++ Q++ ++++ + +E++E QK + + +++ K
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQY--REEEELQRQKRKQRYRDEDQRSDLK 1224
Query: 695 ----KEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEE 750
E E + N ++ K R E ++ + + + + H + E+ E D E+
Sbjct: 1225 WQWEPEKENAVRDN---KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ 1281
Score = 39.7 bits (91), Expect = 0.012
Identities = 40/186 (21%), Positives = 83/186 (44%), Gaps = 14/186 (7%)
Query: 68 KQRLARE----RREEKRRQQDANKETQLLEKE---RKTKLQYEKQME-ERQRKLKERKEK 119
+Q+L RE R ++ RR+Q +E QL ++ R+ +L+ E+Q+ E++ + E+K +
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439
Query: 120 EEQR-RIAAEEKRHQKDEAQKEKFTAILYRTLERRRL-ADDYQQKRWSW----GGSAMAN 173
+E+R + E+ ++D ++E+ T + +++L D +++R W
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499
Query: 174 SESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHS 233
E + R E+ EQ + L +R+ ++ R L R +
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559
Query: 234 STDKEQ 239
+EQ
Sbjct: 560 QERREQ 565
Score = 39.7 bits (91), Expect = 0.012
Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQ-----NET 661
RR RE++ +EEEE Q+EE Q ++ K +E + K + QQ+ E
Sbjct: 982 RRQEREKKYREEEELQQEEEQLLREEREKRRRQE----WERQYRKKDELQQEEEQLLREE 1037
Query: 662 KKKKGWLDQEDQ---EAPLQKGDAKIKAQEEADKRKKEHERIML--QNLQERLERKKRIE 716
++K+ ++E Q E LQ+ + ++ +E +R++E ER + LQ+ E+ R E
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 717 EIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEM 759
+R ++ + + E EE + EE +K E+
Sbjct: 1098 PEKRRRQERERQCREEEELQQ----EEEQLLREEREKRRRQEL 1136
Score = 39.3 bits (90), Expect = 0.016
Identities = 26/146 (17%), Positives = 76/146 (52%), Gaps = 3/146 (2%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E R+ R++EE+ ++ E +QR +++ ++ ++ + E + ++ +QQ + ++
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL--ERQELRRERQEEEQQQQRLRR 302
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRK 724
+ L ++ +E ++ + + + QE +++++ E+ + + +ER E++ R E+ +R R+
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER-RE 361
Query: 725 TDVNASKVTETSSHDIYEEAEADNEE 750
+ + E + E + E+
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQ 387
Score = 39.3 bits (90), Expect = 0.016
Identities = 36/168 (21%), Positives = 79/168 (47%), Gaps = 21/168 (12%)
Query: 605 ELRRLA---------REQREKEEEERQREEMQQRVIKKSKDMAKE----AVGGQAEDHLK 651
+LRR REQ+ + E++ +RE+ ++R +K + +E + D LK
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLK 459
Query: 652 LKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQE---- 707
++ +++E +++K L ++ +E ++ + +K +EE + ++E L+ QE
Sbjct: 460 REEETERHEQERRKQQLKRDQEE---ERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Query: 708 -RLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKD 754
RL+R++ E + +R R + E + E E E+ ++
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
Score = 39.3 bits (90), Expect = 0.016
Identities = 23/96 (23%), Positives = 53/96 (55%), Gaps = 5/96 (5%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKE--EQRRI 125
+++L RE E++RRQ+ +E Q E+E + + + EER+++ ++ E++ E+ +
Sbjct: 1090 EEQLLREEPEKRRRQE---RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
Query: 126 AAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQ 161
EE++ ++E +K + + + E L + +Q
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Score = 39.3 bits (90), Expect = 0.016
Identities = 23/77 (29%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 68 KQRLARERREEKRRQQDANK--ETQLLEKERKTKLQYEKQMEERQRKLKERK--EKEEQR 123
+Q+L R+ R ++RRQ K E + L +ER+ + Q +Q +R+ +L+E+K +E++R
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ-QLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 124 RIAAEEKRHQKDEAQKE 140
+ +E++ ++ E Q++
Sbjct: 1596 KFMEDEQQLRRQEGQQQ 1612
Score = 38.9 bits (89), Expect = 0.021
Identities = 31/137 (22%), Positives = 66/137 (48%), Gaps = 17/137 (12%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E +L RE++EK +ER+R+ ++ +++ K + Q D + +++N +
Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQE----------EADKRKKEHERIMLQNL------QER 708
K + + E Q D++++ ++ E +R +E ER Q +E+
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298
Query: 709 LERKKRIEEIMKRTRKT 725
LER+++ +E +R RK+
Sbjct: 1299 LEREEQ-KEAKRRDRKS 1314
Score = 38.9 bits (89), Expect = 0.021
Identities = 46/218 (21%), Positives = 95/218 (43%), Gaps = 27/218 (12%)
Query: 611 REQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQ 670
R++ EEE+ +REE Q+ K+ ++E E+ + + Q+ + +++ L Q
Sbjct: 1289 RDRHFPEEEQLEREE--QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
Query: 671 EDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNAS 730
E +E PL++ + K +EE + R +E R L+ ++RL R++R + +K ++
Sbjct: 1347 EREEQPLRRQERDRKFREE-ELRHQEQGRKFLEE-EQRLRRQERERKFLKEEQQLRCQER 1404
Query: 731 KVTETSSHD---IYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNNAKKMTHK 787
+ D EE + +E D+ KF+ ++ +
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDR-------------------KFREEEQQVRRQERE 1445
Query: 788 LVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQE 825
FLE+ Q+R+E F + + +++ + QE
Sbjct: 1446 RKFLEE-EQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Score = 38.9 bits (89), Expect = 0.021
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 13/104 (12%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLK--------ERKEK 119
+Q+L R+ R+ K R+Q+ + E ERK L+ E+Q+ +QR+ K R+E+
Sbjct: 1491 EQQLRRQERDRKFREQELRSQ----EPERKF-LEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 120 EEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
+QRR + K ++++ ++E+ L R R+ + Q+ R
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVR 1589
Score = 38.1 bits (87), Expect = 0.036
Identities = 26/136 (19%), Positives = 72/136 (52%), Gaps = 12/136 (8%)
Query: 605 ELRRLAREQREKEEEER---------QREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDG 655
+LRR E+R +++EER Q E +Q++ ++ ++ ++ + + E+ + +
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL 364
Query: 656 QQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRI 715
+++ E ++++ L +E Q L++ + Q+ +++ E+ + + Q R E++ R
Sbjct: 365 RREQEEERREQQLRREQQ---LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 716 EEIMKRTRKTDVNASK 731
E+ ++R ++ + + K
Sbjct: 422 EQQLRREQEEERHEQK 437
Score = 37.7 bits (86), Expect = 0.047
Identities = 38/191 (19%), Positives = 85/191 (44%), Gaps = 40/191 (20%)
Query: 603 LTELRRLAREQREKEEEERQ-REEMQQRVIKKSKDMAKEAVGGQAE----DHLKLKDGQQ 657
L + RR +QR E +RQ EE QR +K ++ +E G+ + + L+ +D Q+
Sbjct: 109 LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168
Query: 658 QNET--KKKKGWLDQEDQEAPLQ-----KG------------------DAKIKAQEEADK 692
++E ++++ W ++E++ A + KG + + K +EE +
Sbjct: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228
Query: 693 RKKEHERIMLQNLQE----------RLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYE 742
+++E + + Q +E R E +K EE +R R+ ++ + ++
Sbjct: 229 QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR 288
Query: 743 EAEADNEESDK 753
E + + ++ +
Sbjct: 289 ERQEEEQQQQR 299
Score = 37.7 bits (86), Expect = 0.047
Identities = 32/171 (18%), Positives = 76/171 (44%), Gaps = 24/171 (14%)
Query: 607 RRLAREQREKEEE--------ERQREEMQQRVIKKSKDMAKEAVGG-------QAEDHLK 651
RR R +RE+EEE E + E +Q + ++ ++ A+E + Q E
Sbjct: 654 RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEAD 713
Query: 652 LKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEE--ADKRKKEHE-------RIML 702
+ + + +K++G +++QE ++ +++++ QEE A ++++E E +
Sbjct: 714 ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQA 773
Query: 703 QNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDK 753
+ ER ++ ++ R+ + A + + + EE E + +
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
Score = 37.7 bits (86), Expect = 0.047
Identities = 28/106 (26%), Positives = 59/106 (55%), Gaps = 14/106 (13%)
Query: 68 KQRLARERREEKRRQQDANK----ETQLLEKERKTKLQYEKQM---EERQRKL---KERK 117
++R + R EE R Q+ K E +L +ER+ K E+Q +ER+++L ++RK
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 118 EKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
+EE+++++ R ++D +E+ + + ER+ L ++ Q ++
Sbjct: 1416 FREEEQQLS----RQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Score = 37.4 bits (85), Expect = 0.061
Identities = 50/250 (20%), Positives = 106/250 (42%), Gaps = 34/250 (13%)
Query: 17 RELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDI-----KQRL 71
R+ R R E+ +++RKQ R S+++ ++P + ++ N + +
Sbjct: 1192 RQERERQYREEEELQRQKRKQRY--RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQ 1249
Query: 72 ARERREEKRRQQDANKETQLL---------EKERKTKLQYEKQM-EERQRKLKERKEKEE 121
R+ + + R + + ++ Q L E+ER+ Q ++ EE Q + +E+KE +
Sbjct: 1250 FRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 122 QRRIAAEEK---RHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKT 178
+ R + EEK R +++E ++ + T +R E +L + +++ + +
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFR--EEEQLLQEREEQ--------PLRRQERD 1359
Query: 179 ANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTD---KERSSSLNRRDSNLHSST 235
R EQG L + L + K + +ER L R+D +
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL-RQDRDRKFRE 1418
Query: 236 DKEQAERKPR 245
+++Q R+ R
Sbjct: 1419 EEQQLSRQER 1428
Score = 36.6 bits (83), Expect = 0.10
Identities = 39/145 (26%), Positives = 69/145 (47%), Gaps = 29/145 (20%)
Query: 62 MLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTK-LQYEKQM--EERQRKLKERKE 118
+L+ +Q+L R+ R+ K R++ E QL +ER+ K LQ E+Q+ +E +RK +E ++
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREE----EQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 119 ------------KEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSW 166
+E R+I EE+ + E Q+ R ER R + +Q R
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQ-------LRRQERDRKFREEEQLRQER 1783
Query: 167 GGSAMANSESKTANKRSASTEKLEQ 191
+ + ES +++ E+L Q
Sbjct: 1784 EEQQLRSQES---DRKFREEEQLRQ 1805
Score = 36.2 bits (82), Expect = 0.14
Identities = 25/126 (19%), Positives = 72/126 (57%), Gaps = 8/126 (6%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E RR + +RE+EEE R+++ +++ ++ + + + E L+ + ++ + ++
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR 403
Query: 665 KGWLDQEDQ---EAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLER-KKRIEEIMK 720
+ L +E Q E L++ + +++ ++E ++ +++HE+ + ++RL+R ++ + +K
Sbjct: 404 EQQLRREQQLRREQQLRR-EQQLRREQEEERHEQKHEQ---ERREQRLKREQEERRDWLK 459
Query: 721 RTRKTD 726
R +T+
Sbjct: 460 REEETE 465
Score = 36.2 bits (82), Expect = 0.14
Identities = 34/157 (21%), Positives = 70/157 (44%), Gaps = 23/157 (14%)
Query: 17 RELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERR 76
R+ R R + ++ ER +Q + + + + L++ R RE
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-- 1799
Query: 77 EEKRRQQDANKETQLLEKERKTKLQYEK---QMEERQRKLK----------------ERK 117
EE+ RQ+ +E QL ++R K ++E+ Q+EE++++L+ E+
Sbjct: 1800 EEQLRQE--REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857
Query: 118 EKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRR 154
+EEQ EE++ +++ +K + I + E +R
Sbjct: 1858 RREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Score = 35.8 bits (81), Expect = 0.18
Identities = 28/142 (19%), Positives = 69/142 (48%), Gaps = 12/142 (8%)
Query: 612 EQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQE 671
EQ EE E++R + +++ ++ +++ +E E+ L +++ E ++++ W Q
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQE------EEQLL----REEREKRRRQEWERQY 1020
Query: 672 DQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASK 731
++ LQ+ + ++ +E +R +E ER + + + E ++ + E + R+ ++
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 732 VTETSSHDIYEEAEADNEESDK 753
E EE + EE +K
Sbjct: 1081 RKEEELQQ--EEEQLLREEPEK 1100
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/108 (24%), Positives = 55/108 (50%), Gaps = 15/108 (13%)
Query: 32 KERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERREEKRRQQDANKETQL 91
+E+R++ + R ++ + ++ K ++ + R EE+ +Q+ E QL
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE----EEQL 1183
Query: 92 LEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQK 139
L +E+ EK+ +ER+R+ +E +E + Q+R K+ +DE Q+
Sbjct: 1184 LREEQ------EKRRQERERQYREEEELQRQKR-----KQRYRDEDQR 1220
Score = 35.8 bits (81), Expect = 0.18
Identities = 29/132 (21%), Positives = 62/132 (46%), Gaps = 10/132 (7%)
Query: 605 ELRRLAREQREKEEEER-----QREEMQQRVIKKSKDMAKEAVGGQAE--DHLKLKDGQQ 657
EL+R R+QR ++E++R Q E ++ ++ +K K Q + +L+D Q
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263
Query: 658 QNETKKKKGWLDQEDQEAP---LQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKR 714
Q + + G + D+E Q+ D +E+ ++ +++ + + QE + +
Sbjct: 1264 QQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE 1323
Query: 715 IEEIMKRTRKTD 726
E +R ++TD
Sbjct: 1324 EREEKRRRQETD 1335
Score = 35.4 bits (80), Expect = 0.23
Identities = 35/164 (21%), Positives = 71/164 (43%), Gaps = 14/164 (8%)
Query: 14 PSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVI----DGSMLKNDIKQ 69
P LRE R R + A +E+R R K + + + + + Q
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQ 847
Query: 70 RLARERR-----EEKRRQQDANKETQL---LEKERKTKLQ--YEKQMEERQRKLKERKEK 119
+L E +E+RR Q+ ++ + LE+ERK + Y K + Q + +++ +
Sbjct: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
Query: 120 EEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
EE+ + EE+ ++ + Q+ ++ E +L + ++KR
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Score = 35.0 bits (79), Expect = 0.30
Identities = 27/147 (18%), Positives = 77/147 (52%), Gaps = 11/147 (7%)
Query: 607 RRLAREQR-----EKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNET 661
+RL REQ+ E+E E+Q E +Q+ ++ ++ +E + ++ + + +++ E
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 662 KKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKK-EHERIMLQNLQERLERKKRIEEIMK 720
++++ L +E +E ++ + +++ +++ + ++ E+ + + Q R E++ R E+ ++
Sbjct: 358 ERREQQLRREQEE---ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414
Query: 721 RTR--KTDVNASKVTETSSHDIYEEAE 745
R + + + + E H+ E E
Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQE 441
Score = 34.7 bits (78), Expect = 0.40
Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 9/74 (12%)
Query: 68 KQRLARER-REEKRRQQDANKETQLLEKERKTKLQYEKQM--EERQRKLKE----RKEKE 120
+QRL +ER R+ + +Q A +E +E + Q E+Q +ER+RKL+E R++KE
Sbjct: 1834 EQRLRQERDRQYRAEEQFATQEKS--RREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 121 EQRRIAAEEKRHQK 134
EQR E + Q+
Sbjct: 1892 EQRHRQVGEIKSQE 1905
Score = 34.3 bits (77), Expect = 0.52
Identities = 27/129 (20%), Positives = 68/129 (52%), Gaps = 14/129 (10%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKD-------MAKEAVGGQAEDHLKLKDGQQQN 659
RR +E+R +++ R++EE +++ +++ ++ + +E + E L+ + ++
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 660 ETKKKKGWLDQEDQ---EAPLQKGDAKIKAQ----EEADKRKKEHERIMLQNLQERLERK 712
+ +++ L +E Q E L++ + Q E+ +R++E ER ++ QER E++
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 713 KRIEEIMKR 721
+ E+ +R
Sbjct: 447 LKREQEERR 455
Score = 33.5 bits (75), Expect = 0.89
Identities = 32/153 (20%), Positives = 73/153 (47%), Gaps = 15/153 (9%)
Query: 603 LTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQ------AEDHLKLKDGQ 656
L E +R + +E ++R++EE Q+R + + + +E GQ E +L +G+
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEP--GQRRRQKRQEQERELAEGE 152
Query: 657 QQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERL----ERK 712
+Q+E +++ L+Q D++ ++ + + +E ++R+ E E++ E E +
Sbjct: 153 EQSEKQER---LEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
Query: 713 KRIEEIMKRTRKTDVNASKVTETSSHDIYEEAE 745
R E+++ RK + +++E E
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
Score = 33.5 bits (75), Expect = 0.89
Identities = 33/167 (19%), Positives = 79/167 (47%), Gaps = 11/167 (6%)
Query: 594 MNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLK 653
+ E ++ L+R E+ E+EE QR + ++ ++ + + K + E+ + +
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE---EQEERRQQQ 646
Query: 654 DGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKK 713
++Q E ++++ L +E++E L++ ++K + E ++R++E + +ER+ K
Sbjct: 647 LRREQQERREQR--LKREEEEERLEQ---RLKREHEEERREQELAEEEQEQARERI--KS 699
Query: 714 RIEEIM-KRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEM 759
RI + + + D SKV + + EE + +E+
Sbjct: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Score = 33.5 bits (75), Expect = 0.89
Identities = 31/129 (24%), Positives = 67/129 (51%), Gaps = 16/129 (12%)
Query: 607 RRLAREQREKE------EEERQREE--------MQQRVIKKSKDMAKEAVGGQAEDHLKL 652
RR ++EQR + EEER+R +Q+++ K+ + + +E Q E+ K
Sbjct: 862 RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR 921
Query: 653 KDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRK-KEHERIMLQNLQERLER 711
+ +Q+ + ++++ L QE+++ ++ + + + + E RK K+ ++ Q L E E+
Sbjct: 922 RRQEQERQYREEEQ-LQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Query: 712 KKRIEEIMK 720
++R E K
Sbjct: 981 RRRQEREKK 989
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 57.0 bits (136), Expect = 7e-08
Identities = 156/768 (20%), Positives = 287/768 (37%), Gaps = 159/768 (20%)
Query: 55 KPVIDGSMLKNDIKQ-RLARE----RREEKRRQQDANKETQLLEKERKTKLQYEKQMEER 109
K ID +LKN +Q +RE EE +++++ K+ + E E+ + +E R
Sbjct: 206 KAQIDPVLLKNSSQQDNSSRESPSLEDEETKKEEETPKQEEQKESEKMKSEEQPMDLENR 265
Query: 110 QRK--LKE---RKEKEEQRRIAA--------------EEKRHQKDEAQ--KEKFTAILYR 148
L+E +KEKE+++ + EEK+ K+E+ KE I
Sbjct: 266 STANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFKENVKPIKVE 325
Query: 149 TLERRRLADD----------YQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALI- 197
E R D + +R +GG+ ++ E K + TEKL+ A I
Sbjct: 326 VKECRADPKDTKSSMEKPVAQEPERIEFGGNIKSSHE--ITEKSTEETEKLKNDQQAKIP 383
Query: 198 ---RQMPLSS-------AGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVT 247
R++ LS L SV K + S+ E K V
Sbjct: 384 LKKREIKLSDDFDSPVKGPLCKSVTPTKEFLKDEIKQEEETCKRISTITALGHEGKQLVN 443
Query: 248 GVTN---YVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQ-----------TKVEESPLE 293
G + + T P+ + P I + T ++ LE
Sbjct: 444 GEVSDERVAPNFKTEPIETKFYETKEESYSPSKDRNIITEGNGTESLNSVITSMKTGELE 503
Query: 294 KVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYD 353
K P + D+ V +E+ + P PE+ T S
Sbjct: 504 KETAPLRKDADSSISV-LEIHSQKAQIEEPDP-----PEMET--------------SLDS 543
Query: 354 SEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGS 413
SEM+ D S + ++ + ++ K SP+ + P + LE L ++ E + +
Sbjct: 544 SEMAKDLSSKTALSSTESCTMKGEEK-----SPKTKKDKRPPI-LECLEKL--EKSKKTF 595
Query: 414 LEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKS 473
L+ + + + P+E K + + SPEA + P ++ + + + + + S
Sbjct: 596 LDKDAQRLSPI-PEEVPKSTLESEKPGSPEAAETSPPSNIIDHCEKLASEKEVVECQSTS 654
Query: 474 EMDKQALIPIAKKRL---SSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLIS 530
+ Q++ + + L S +T+ + G+ P T +QK+
Sbjct: 655 TVGGQSVKKVDLETLKEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQKS---------- 704
Query: 531 KQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKST 590
F YK++P + T + ++ T +++KE + K T R + ++
Sbjct: 705 ------KFKYKLVPEEETTASENTEITSERQKEGI-KLTIRISSRKKK------------ 745
Query: 591 AGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHL 650
++ K+L + +E+ EKEEE+ +R + S+ AK A
Sbjct: 746 -----PDSPPKVLEPENK--QEKTEKEEEKTNVGRTLRRSPRISRPTAKVA--------- 789
Query: 651 KLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAK-IKAQEEADKRKKEHERIMLQNLQERL 709
+++D Q+ + K+ +G + E++ LQK D K I + E D K ++
Sbjct: 790 EIRD--QKADKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSK----------VSKV 837
Query: 710 ERKKRIEEIMKRTR------KTDVNASKVTETSSHDIYEEAEADNEES 751
+ K ++ RTR D + +E SS EE E ++EE+
Sbjct: 838 KPKGKVRWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEKESEEA 885
Score = 39.7 bits (91), Expect = 0.012
Identities = 33/183 (18%), Positives = 76/183 (41%), Gaps = 12/183 (6%)
Query: 67 IKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIA 126
++Q R+ K++ D ++E + E R ++ + + + + R+ + Q+R
Sbjct: 1156 MRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQI 1215
Query: 127 AEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGS---AMANSESKTANKRS 183
++ + D +QK R + +RRL+ ++ + S +A ++ KR
Sbjct: 1216 NYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSVRKRG 1275
Query: 184 ASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERK 243
ST++ + + S + + + +TD+E S N H ++ + +
Sbjct: 1276 RSTDEYSEADEEEEEEEGKPS---RKRLHRIETDEEESC------DNAHGDANQPARDSQ 1326
Query: 244 PRV 246
PRV
Sbjct: 1327 PRV 1329
Score = 35.8 bits (81), Expect = 0.18
Identities = 26/108 (24%), Positives = 58/108 (53%), Gaps = 9/108 (8%)
Query: 617 EEEERQREEMQQRVIKKSKDMAKEAVGGQAE-DHLKLKDGQQQNETKKKKGWLDQEDQEA 675
EE++ Q + +++ ++A+ +A+ D + LK+ QQ+ + ++ L ED+E
Sbjct: 178 EEQDDQDGSSWKCIVRNRNELAETLALLKAQIDPVLLKNSSQQDNSSRESPSL--EDEET 235
Query: 676 PLQKGDAKIKAQEEADKRKKEHERIMLQN------LQERLERKKRIEE 717
++ K + Q+E++K K E + + L+N L+E +K++ +E
Sbjct: 236 KKEEETPKQEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDE 283
Score = 33.1 bits (74), Expect = 1.2
Identities = 39/223 (17%), Positives = 98/223 (43%), Gaps = 26/223 (11%)
Query: 43 VATHSSNIRSTFKPVIDGSMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQY 102
++T + + ++D +N QR A RR+++RR D + ++ L E+E + + +
Sbjct: 1052 ISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKI 1111
Query: 103 EKQMEERQRKLKERKEKEEQRRIAAEE-------KRHQKDEAQKEKFTAILYRTLERRRL 155
++ E ++ E+ + ++ +R ++ ++ + + L R +++
Sbjct: 1112 SDGSQDEFVVSDENPDESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKY 1171
Query: 156 ADDYQQKRWSWGGSAMANSE---------SKTANKRSASTEKLEQGTSALIRQMPLSSAG 206
+DD +++ S S + S+ +T +RS +K + + + S G
Sbjct: 1172 SDDDEEEE-SEENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQ-----INYKEDSESDG 1225
Query: 207 LQNSVAK----RKTDKERSSSLNRRDSNLHSSTDKEQAERKPR 245
Q S+ + R+ K R SS +S L +++ ++ ++ +
Sbjct: 1226 SQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESK 1268
Score = 32.0 bits (71), Expect = 2.6
Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 2/148 (1%)
Query: 609 LAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWL 668
L E+ +KEEE ++EE ++ KS++ + + L+ +++ E +K+ L
Sbjct: 230 LEDEETKKEEETPKQEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKL 289
Query: 669 DQ-EDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDV 727
E PL + + K +EE+D K+ + I ++ + R + K + K +
Sbjct: 290 PVIVKLEKPLPENEEKKIIKEESDSFKENVKPIKVEVKECRADPKDTKSSMEKPVAQEPE 349
Query: 728 NAS-KVTETSSHDIYEEAEADNEESDKD 754
SSH+I E++ + E+ D
Sbjct: 350 RIEFGGNIKSSHEITEKSTEETEKLKND 377
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 57.0 bits (136), Expect = 7e-08
Identities = 53/204 (25%), Positives = 101/204 (49%), Gaps = 16/204 (7%)
Query: 49 NIRSTF---KPVIDGSMLKNDIK----QRLARERREEKRRQQDANKETQLLEKERKTKLQ 101
NI+ +F K + D S+ K ++ Q L ++R E+KRR+++A +E Q E+ ++ +L+
Sbjct: 252 NIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEA-EERQRAEERKQKELE 310
Query: 102 YEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQ 161
++ +R+ KL++R++K+ R + +K+ +K +A+++K + ER+ L Q+
Sbjct: 311 ELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLL--AQR 368
Query: 162 KRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKR-KTDKER 220
S A S +K R + EQ L Q LQ + +R + +KER
Sbjct: 369 NLQSIRLIAELLSRAKAVKLR-----EQEQKEEKLRLQQQEERRRLQEAELRRVEEEKER 423
Query: 221 SSSLNRRDSNLHSSTDKEQAERKP 244
+ L R++ L +KP
Sbjct: 424 ALGLQRKERELRERLLSILLSKKP 447
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/167 (22%), Positives = 81/167 (48%), Gaps = 18/167 (10%)
Query: 582 YEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEA 641
++ + + S A I + + L EL + EQ+ +E+E +R+ ++R K+ +++ +E
Sbjct: 257 FDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERER 316
Query: 642 VGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKG-DAKIKAQEE---ADKRKKEH 697
+ E+ L+ ++ Q+Q + + ++ E +A QK KIK +E +R +
Sbjct: 317 ---KREEKLRKRE-QKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQS 372
Query: 698 ERIMLQNL----------QERLERKKRIEEIMKRTRKTDVNASKVTE 734
R++ + L QE+ E K R+++ +R R + +V E
Sbjct: 373 IRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEE 419
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 56.6 bits (135), Expect = 1e-07
Identities = 29/96 (30%), Positives = 60/96 (62%), Gaps = 6/96 (6%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAA 127
K+ +E+R+EKR++++ K+T+ EK + EK+ EE++RK K +K+KEE+ R
Sbjct: 25 KEGKRKEKRKEKRKEKEKKKKTKETEKRK------EKEEEEKKRKRKRKKKKEEEEREEE 78
Query: 128 EEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
EE+ ++ E ++++ + +RRR ++ ++K+
Sbjct: 79 EEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 47.0 bits (110), Expect = 8e-05
Identities = 25/112 (22%), Positives = 59/112 (52%)
Query: 80 RRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQK 139
++++ KET+ E+ +T+ + EK+ + ++++ ++RKEKE++++ EKR +K+E +K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 140 EKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQ 191
++ + E R ++ +++ K KR E+ E+
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
K K+ E+R+EK ++ K + +KE + + + E++ EE KE +EKEE R
Sbjct: 40 KEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE----KEEEEKEEGR 95
Query: 124 RIAAEEKRHQKDEAQKEK 141
R ++KR +K+E +++K
Sbjct: 96 RRKKKKKRRRKEEEEEKK 113
Score = 44.3 bits (103), Expect = 5e-04
Identities = 26/109 (23%), Positives = 57/109 (52%), Gaps = 9/109 (8%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKE-------- 115
K + ++ E EE+ ++ KE + +++ K K + K+ E+R+ K +E
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 116 -RKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKR 163
+K++EE+R EE+ +K+E +KE+ + RR+ ++ ++K+
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Score = 43.5 bits (101), Expect = 9e-04
Identities = 31/122 (25%), Positives = 66/122 (54%), Gaps = 11/122 (9%)
Query: 604 TELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKK 663
TE E E+EE+E +R+E ++ +K K+ K+ + E + ++ +++ + K+
Sbjct: 10 TEETEETEETEEEEEKEGKRKEKRK---EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 664 KKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTR 723
KK ++E +E ++ + K + ++E +R+K+ ++ + +E E KK+ KR R
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK---RRRKEEEEEKKK-----KRRR 118
Query: 724 KT 725
KT
Sbjct: 119 KT 120
Score = 43.1 bits (100), Expect = 0.001
Identities = 18/78 (23%), Positives = 47/78 (60%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
K K++ E E + +++ KE + EK ++ + + EK+ + ++ + ++ KE+EE++
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 124 RIAAEEKRHQKDEAQKEK 141
R +K+ +++E ++E+
Sbjct: 62 RKRKRKKKKEEEEREEEE 79
Score = 42.7 bits (99), Expect = 0.001
Identities = 19/76 (25%), Positives = 46/76 (60%)
Query: 66 DIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRI 125
+ ++R +E E+KR+++ K+ + +E + + + EK+ EE++ + +K+K+ +R+
Sbjct: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107
Query: 126 AAEEKRHQKDEAQKEK 141
EEK+ ++ K+K
Sbjct: 108 EEEEKKKKRRRKTKKK 123
Score = 42.4 bits (98), Expect = 0.002
Identities = 18/69 (26%), Positives = 43/69 (62%)
Query: 73 RERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRH 132
++++++K+ ++ + + E+E K + EK+ E+R+ K K++K KE ++R EE+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 133 QKDEAQKEK 141
++ +K+K
Sbjct: 61 KRKRKRKKK 69
Score = 41.2 bits (95), Expect = 0.004
Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 15/125 (12%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKG 666
++ +E E EE E EE ++ K K+ KE K K+ +++ +TK+ +
Sbjct: 4 KKKKKETEETEETEETEEEEEKE--GKRKEKRKE----------KRKEKEKKKKTKETEK 51
Query: 667 WLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTD 726
++E++E +K K K ++E ++R++E E + +E E +R ++ KR RK +
Sbjct: 52 RKEKEEEE---KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108
Query: 727 VNASK 731
K
Sbjct: 109 EEEKK 113
Score = 40.8 bits (94), Expect = 0.006
Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 5/97 (5%)
Query: 658 QNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEE 717
+ + KKKK + E+ E ++ + + K +E+ +++KE E+ + +E +RK++ EE
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK--KKKTKETEKRKEKEEE 58
Query: 718 IMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKD 754
KR RK K E + EE E + EE +K+
Sbjct: 59 EKKRKRK---RKKKKEEEEREEEEEEEEEEKEEEEKE 92
Score = 38.5 bits (88), Expect = 0.028
Identities = 20/78 (25%), Positives = 50/78 (64%), Gaps = 4/78 (5%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKE---RKEK-EEQR 123
K++ +++ E+ + + +E + E +RK K + +++ +E+++K KE RKEK EE++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 124 RIAAEEKRHQKDEAQKEK 141
+ + K+ +++E ++E+
Sbjct: 61 KRKRKRKKKKEEEEREEE 78
Score = 33.5 bits (75), Expect = 0.89
Identities = 24/119 (20%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 546 QHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTE 605
+ T + T +++++ + R E ++ ++ K T E K
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKE---KKKKTKETEKRKEKEEEEKKRKR 64
Query: 606 LRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
R+ +E+ E+EEEE + EE ++ K+ K+ + ++ + K +++ +TKKK
Sbjct: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 56.6 bits (135), Expect = 1e-07
Identities = 57/220 (25%), Positives = 99/220 (45%), Gaps = 15/220 (6%)
Query: 319 MEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVP 378
M+ A G AP + P S + P + +P L EA P+ E P
Sbjct: 1 MDRGAAAAQGTAPPQDGEQ-PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCP 59
Query: 379 KVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESM 438
+++ PEA+ E+ E+ E PE + E A E + E + + E A + + + +P+ +
Sbjct: 60 ELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPAT 119
Query: 439 EASPEAMVKASPKTSLEASMEASPKAKARDAPKKS-EMDKQALIPIAKKRLSSYTECYKW 497
E++PE +P+ +LE+ E +P+ AP+ + E + + +A + ++
Sbjct: 120 ESAPE----PTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRP 175
Query: 498 SSSPENACGLPSPISTNRQIQKNCP-PSPLPLISKQSPQT 536
S +P C L P+ T + K P PSP P SP+T
Sbjct: 176 SPAP---CLLQCPVDTRERGLKTSPSPSPSP-----SPRT 207
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 56.2 bits (134), Expect = 1e-07
Identities = 48/178 (26%), Positives = 79/178 (44%), Gaps = 8/178 (4%)
Query: 73 RERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRH 132
+ER EK RQ+ +E Q EKE KT+ ++ ++ ER+R+ + E E +R+ E R
Sbjct: 177 KEREREKNRQERRERERQR-EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
Query: 133 QKDEAQKEKFTAILYRTLERRRLAD---DYQQKRWSWGGSAMANSESKTANKRSASTEKL 189
+K E ++EK A R ER D + ++ R E +T KR TE+
Sbjct: 236 RKTEREREK-QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Query: 190 EQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVT 247
+ RQ +N +R+ ++ER R +KE+ ++ R T
Sbjct: 295 RETERKRERQRERERERERNRKRERERERERE---RERQRETERDREKERERKRKRQT 349
Score = 53.1 bits (126), Expect = 1e-06
Identities = 48/199 (24%), Positives = 88/199 (44%), Gaps = 21/199 (10%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQME---------------- 107
K D + R+R +E+ RQ D ++ Q EKER + + E++ E
Sbjct: 90 KRDRHRERQRDREKERERQTDRERDRQ-REKERNRQKERERETEREGERGRDRQTDGQRE 148
Query: 108 -ERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSW 166
ERQR ++ +E++ R + +R+++ E ++EK R ER+R ++ + R S
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREK-NRQERRERERQREKENKTEDRHSE 207
Query: 167 GGSAMANS-ESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLN 225
G E++T +R T++ R+ + + S + + DKER +
Sbjct: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
Query: 226 R-RDSNLHSSTDKEQAERK 243
R RD + + Q +RK
Sbjct: 268 RDRDRDRRQKERERQTDRK 286
Score = 52.4 bits (124), Expect = 2e-06
Identities = 47/211 (22%), Positives = 94/211 (44%), Gaps = 13/211 (6%)
Query: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGI-MNAEAATKILTELRRLAREQREKE 617
+K++E R E QR + S G E T+ TE +R +R+++
Sbjct: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
Query: 618 -------EEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQ 670
E++ +RE +R ++ K+ +E + D + K+ ++Q + K+++
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERD 294
Query: 671 EDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNAS 730
+ E ++ + + +E KR++E ER + Q ER + E KR R+T+++
Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Query: 731 KVTETSSHDIYEEAEADNE---ESDKDSLNE 758
+ +T + +AE + E E D+ S E
Sbjct: 355 RNRQT-GREGRRQAERERERERERDRQSARE 384
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/180 (18%), Positives = 78/180 (43%), Gaps = 9/180 (5%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAA 127
+QR RE++ ++ A++ +KER+ + ++ + RQ++ + + +++ QRR
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 128 EEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTE 187
+ + +K E Q+E+ R R+R + +++ + E + KR TE
Sbjct: 294 DRETERKRERQRERERE---RERNRKRERERERERERERQRETERDREKERERKRKRQTE 350
Query: 188 KLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVT 247
+ R G + + +R+ ++ER R D+++ + + R T
Sbjct: 351 MDRE------RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404
Score = 48.1 bits (113), Expect = 3e-05
Identities = 46/196 (23%), Positives = 89/196 (45%), Gaps = 29/196 (14%)
Query: 73 RERREEK--RRQQDANKETQL---LEKERKTKLQYEKQMEERQRKLKERK---------- 117
RERR EK R++D ++E Q E+ER+T + ++Q E+ + + KER+
Sbjct: 79 RERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERG 138
Query: 118 -------EKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSA 170
++E +R+ AE++R ++ + ++++ T R ++ R + +Q+R
Sbjct: 139 RDRQTDGQRERERQRDAEKERERQTDRERQRQTE---RNRQKEREREKNRQERRE--RER 193
Query: 171 MANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNR-RDS 229
E+KT ++ S + E+ + +RKT++ER R R S
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERD-RQRKTEREREKQAERERAS 252
Query: 230 NLHSSTDKEQAERKPR 245
+ DKE+ + R
Sbjct: 253 ERETERDKERERERDR 268
Score = 47.8 bits (112), Expect = 5e-05
Identities = 39/180 (21%), Positives = 73/180 (40%), Gaps = 1/180 (0%)
Query: 66 DIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRI 125
D ++R ++ RE +R ++ +ET + R+ K ++ K+ R+R+ KE+E Q
Sbjct: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR 111
Query: 126 AAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSAS 185
+ +R ++ QKE+ R ER R Q+ A E +T +R
Sbjct: 112 ERDRQREKERNRQKER-ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ 170
Query: 186 TEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPR 245
TE+ Q + + + KT+ S R+ + T+ E+ + R
Sbjct: 171 TERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDR 230
Score = 45.8 bits (107), Expect = 2e-04
Identities = 42/203 (20%), Positives = 86/203 (42%), Gaps = 32/203 (15%)
Query: 73 RERREEKRRQQDANKETQLLEKERKTKLQYEKQME-------------ERQRKLKERKEK 119
R+RR+++R +Q K + E++R+T+ + E+Q E ER+R+ + +++
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Query: 120 EEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTA 179
E +R E +R +K + + ++ RR+ + +++R SA E +
Sbjct: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Query: 180 NKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNR-----------RD 228
R E+ RQ G + + +R+ +K+R S R R+
Sbjct: 392 RDRDRQKER--------ERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRE 443
Query: 229 SNLHSSTDKEQAERKPRVTGVTN 251
+ TD++ ++ R T N
Sbjct: 444 RDRERQTDRQAGRQRKRSTLYVN 466
Score = 45.1 bits (105), Expect = 3e-04
Identities = 33/163 (20%), Positives = 76/163 (46%), Gaps = 11/163 (6%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKG 666
R RE++ E +RQRE+ + R ++ ++ +E G+ ++ ++Q + +K++
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERE 160
Query: 667 WLDQEDQEAPLQKGDAKIKAQEE--ADKRKKEHERIMLQNLQER-------LERKKRIEE 717
+++ ++ K + +E+ ++R++E +R ++R ER++ E
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
Query: 718 IMKRTRKTD--VNASKVTETSSHDIYEEAEADNEESDKDSLNE 758
+R R+TD + + TE E A E+++D E
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Score = 45.1 bits (105), Expect = 3e-04
Identities = 42/192 (21%), Positives = 93/192 (48%), Gaps = 16/192 (8%)
Query: 64 KNDIKQRLARERREEK-RRQQDANKET-----QLLEKERKTKLQYEKQME-ERQRKLKER 116
+ D ++ R+R ++ RRQ++ ++T + E++R+T+ + E+Q E ER+R+ +
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316
Query: 117 KEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSE- 175
+E+E +R E +R + + +KE+ R +R+ D + ++ G A E
Sbjct: 317 RERERERERERERQRETERDREKER-----ERKRKRQTEMDRERNRQTGREGRRQAERER 371
Query: 176 --SKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHS 233
+ +++SA + + RQ ++ +R+T+K+R + R+S
Sbjct: 372 ERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD-RESERGR 430
Query: 234 STDKEQAERKPR 245
+E+ ++K R
Sbjct: 431 ERGREREKQKGR 442
Score = 44.7 bits (104), Expect = 4e-04
Identities = 32/149 (21%), Positives = 72/149 (48%), Gaps = 7/149 (4%)
Query: 611 REQREKEEEERQREEMQ-QRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLD 669
RE+ ++E ER+RE+ Q +R + ++ +E +D + +D ++ + ++K
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRRE------KDRHRKRDRHRERQRDREKERER 107
Query: 670 QEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNA 729
Q D+E Q+ + + +E + ++E ER + + ER+++ + +R R+TD
Sbjct: 108 QTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRER 167
Query: 730 SKVTETSSHDIYEEAEADNEESDKDSLNE 758
+ TE + E + E +++ E
Sbjct: 168 QRQTERNRQKEREREKNRQERRERERQRE 196
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/131 (25%), Positives = 63/131 (48%), Gaps = 9/131 (6%)
Query: 604 TELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKK 663
TE R +REK +ER+ E Q+ K++D E G + E ++ + + ET++
Sbjct: 171 TERNRQKEREREKNRQERRERERQREKENKTEDRHSER-GRERE-----RERETETETER 224
Query: 664 KKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTR 723
K+ + D++ ++ K +E A +R+ E ++ + +ER + R +R R
Sbjct: 225 KRQTDRERDRQRKTEREREKQAERERASERETERDK---ERERERDRDRDRDRRQKERER 281
Query: 724 KTDVNASKVTE 734
+TD + TE
Sbjct: 282 QTDRKRQRRTE 292
Score = 44.7 bits (104), Expect = 4e-04
Identities = 32/151 (21%), Positives = 73/151 (48%), Gaps = 12/151 (7%)
Query: 611 REQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQ 670
R++R+KE ERQ + +QR ++ ++ ++ + ++ +++ E +K+ +
Sbjct: 272 RDRRQKER-ERQTDRKRQRRTERDRETERK--------RERQRERERERERNRKRERERE 322
Query: 671 EDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNAS 730
++E Q+ + + +E KRK++ E +N Q E +++ E +R R+ D ++
Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA 382
Query: 731 KVTETSSHDIYEEAEADNE---ESDKDSLNE 758
+ E D + + + E E D+D E
Sbjct: 383 REREERERDRDRDRQKERERQTEKDRDGQRE 413
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/147 (22%), Positives = 72/147 (48%), Gaps = 5/147 (3%)
Query: 604 TELRRLAREQREKE-EEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETK 662
T+ +R R +R++E E +R+R+ ++R ++++ +E + + + + ++ E +
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
Query: 663 KKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRT 722
+K+ + D+E Q G + E +R++E +R + +ER ER + + +R
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER-ERDRDRDRQKERE 401
Query: 723 RKTDVNASKVTETSSHDIYEEAEADNE 749
R+T+ + ET E E D E
Sbjct: 402 RQTEKDRDGQRETEKQ---REREKDRE 425
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/181 (21%), Positives = 77/181 (42%), Gaps = 8/181 (4%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAA 127
++R + +R A+K+ ++ER + + E++ E+RQ + +E K E+RR
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTE-RETDRKRERRR--- 83
Query: 128 EEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTE 187
E+ RH+K + +E+ R ER R D + ++ + E +T + +
Sbjct: 84 EKDRHRKRDRHRERQRD---REKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
Query: 188 KLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNR-RDSNLHSSTDKEQAERKPRV 246
+ G RQ + + +R+ ER+ R R+ N ++E+ K
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 247 T 247
T
Sbjct: 201 T 201
Score = 40.8 bits (94), Expect = 0.006
Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 12/190 (6%)
Query: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEE 618
+++KE +T + + ++R E + E K E R RE+ + E
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER-ERERERQRE 332
Query: 619 EERQREEMQQRVIKKSKDMAKE----------AVGGQAEDHLKLKDGQQQNETKKKKGWL 668
ER RE+ ++R K+ +M +E + + + +D Q E ++++
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
Query: 669 DQEDQEAPLQKGDAKIKAQEEADK-RKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDV 727
D++ Q+ ++ + Q E +K R++E +R + + ER+K+ R R+TD
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDR 452
Query: 728 NASKVTETSS 737
A + + S+
Sbjct: 453 QAGRQRKRST 462
Score = 39.3 bits (90), Expect = 0.016
Identities = 47/215 (21%), Positives = 86/215 (40%), Gaps = 27/215 (12%)
Query: 552 QSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAR 611
Q+ T +K++ K +R RH + K + E + E R
Sbjct: 70 QTERETDRKRERRREKDRHRKR---DRHRERQRDREKERERQTDRERDRQREKERNRQKE 126
Query: 612 EQREKEEE---------ERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETK 662
+RE E E + QRE +QR +K ++ + + + + +Q E +
Sbjct: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERERQTD------RERQRQTERNRQKERE 180
Query: 663 KKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRT 722
++K ++ ++E +K + K ++ +R +E ER + + ERK++ + R
Sbjct: 181 REKNRQERRERERQREKEN---KTEDRHSERGRERER--ERETETETERKRQTDRERDRQ 235
Query: 723 RKTDVNASKVTETSSHDIYEEAEADNE---ESDKD 754
RKT+ K E E E D E E D+D
Sbjct: 236 RKTEREREKQAERERAS-ERETERDKERERERDRD 269
Score = 38.5 bits (88), Expect = 0.028
Identities = 23/89 (25%), Positives = 48/89 (53%), Gaps = 8/89 (8%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKER-----KE 118
+ ++R RER ++ RQ++ ++T EK+R + + EKQ E + + ER +E
Sbjct: 379 RQSAREREERERDRDRDRQKERERQT---EKDRDGQRETEKQREREKDRESERGRERGRE 435
Query: 119 KEEQRRIAAEEKRHQKDEAQKEKFTAILY 147
+E+Q+ + +R +A +++ + LY
Sbjct: 436 REKQKGRERDRERQTDRQAGRQRKRSTLY 464
Score = 38.1 bits (87), Expect = 0.036
Identities = 22/77 (28%), Positives = 43/77 (55%), Gaps = 4/77 (5%)
Query: 68 KQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQME-ERQRKLKERKEKEEQRRIA 126
+ R + REE+ R +D +++ E+ER+T+ + Q E E+QR+ ++ +E E R
Sbjct: 377 RDRQSAREREERERDRDRDRQK---ERERQTEKDRDGQRETEKQREREKDRESERGRERG 433
Query: 127 AEEKRHQKDEAQKEKFT 143
E ++ + E +E+ T
Sbjct: 434 REREKQKGRERDRERQT 450
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 56.2 bits (134), Expect = 1e-07
Identities = 60/248 (24%), Positives = 111/248 (44%), Gaps = 22/248 (8%)
Query: 32 KERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLA---RERREEKRRQQDANKE 88
KER + + A I++ I + + +++ A RERRE + R++ +E
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEE 321
Query: 89 TQLLEKERKTKLQYEKQMEERQR-KLKERKEKEEQRRIAAEEKR----HQKDEAQKEKFT 143
+ E+ ++ K + ++ EERQR K +E++ EE++RI EEKR Q+ A++E+
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKA 381
Query: 144 AI----LYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQ 199
+ + LE ++ A Q+ G E K N++ A +KL+ T+ L +Q
Sbjct: 382 KVEEQKRNKQLEEKKHA---MQETKIKGEKVEQKIEGKWVNEKKAQEDKLQ--TAVLKKQ 436
Query: 200 MPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTD-----KEQAERKPRVTGVTNYVM 254
+Q K + DK +D + + K +RK T V +
Sbjct: 437 GEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNG 496
Query: 255 QYVTVPLR 262
+++T L+
Sbjct: 497 EFMTHKLK 504
Score = 52.4 bits (124), Expect = 2e-06
Identities = 61/312 (19%), Positives = 127/312 (40%), Gaps = 38/312 (12%)
Query: 552 QSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAR 611
+ S + ++ + R EA R E K+ A+ +I E + A+
Sbjct: 245 EQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ 304
Query: 612 EQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQE 671
E+ +E EER+R +++ + + KE AE+ ++K+ +++ ++++ + +E
Sbjct: 305 ERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR--IKEE 362
Query: 672 DQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASK 731
++ A ++ A+ EE +K K E ++ R K++EE ++T + K
Sbjct: 363 EKRAAEERQRAR---AEEEEKAKVEEQK-----------RNKQLEEKKHAMQETKIKGEK 408
Query: 732 VTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNNAK----KMTHK 787
V E+ ++K + + +A+L G K+ K K T K
Sbjct: 409 V---------EQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFK 459
Query: 788 LVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTTKTRKADE 847
++D + KEPK ++K+F + T + + + +H K +
Sbjct: 460 KEEIKDEKIKKDKEPKE----EVKSFMDRKKGFTEV-----KSQNGEFMTHKLKHTENTF 510
Query: 848 TNTTSRSSAQTK 859
+ R+S TK
Sbjct: 511 SRPGGRASVDTK 522
Score = 50.1 bits (118), Expect = 9e-06
Identities = 56/242 (23%), Positives = 100/242 (41%), Gaps = 18/242 (7%)
Query: 20 RARMVAAANEIAKERRKQDVVNR---------VATHSSNIRSTFKPVIDGSMLKNDIKQR 70
RAR+ A A+ER +++ R A I+ K + + ++R
Sbjct: 292 RARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 351
Query: 71 LARERREEKRRQQDANKETQLLEKERKTKLQYE-----KQMEERQRKLKERKEKEEQRRI 125
A ER+ K ++ A +E Q E + K + E KQ+EE++ ++E K K E+
Sbjct: 352 AAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411
Query: 126 AAEEKRHQKDEAQKEKF-TAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSA 184
E K + +AQ++K TA+L + E + ++++ E K K
Sbjct: 412 KIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD-EKIKK 470
Query: 185 STEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKP 244
E E+ S + R+ + QN K ++ +R +S D ++AE P
Sbjct: 471 DKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGG--RASVDTKEAEGAP 528
Query: 245 RV 246
+V
Sbjct: 529 QV 530
Score = 44.7 bits (104), Expect = 4e-04
Identities = 121/698 (17%), Positives = 260/698 (37%), Gaps = 105/698 (15%)
Query: 74 ERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQ 133
ERR E RRQ+ +E LE ER + Y++ ++ + +ER+ + Q R+ ++ Q
Sbjct: 5 ERRRELRRQK---REEMRLEAER---IAYQRNDDDEEEAARERRRRARQERL----RQKQ 54
Query: 134 KDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQG- 192
++E+ + + + + D + K + + E+ + + E+ ++
Sbjct: 55 EEESLGQVTDQV---EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRL 111
Query: 193 TSALIRQ-----------MPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAE 241
AL RQ + L S +QN A+ +T ++ S +R+ ++ + E
Sbjct: 112 QEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQ--------ERYEIE 163
Query: 242 RKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKA 301
VT Y R + + + +E E+ E P +
Sbjct: 164 ETETVT------KSYQKNDWRDAEEN----------------KKEDKEKEEEEEEKPKRG 201
Query: 302 SVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDAS 361
S+ + VEV S + V M+ + + +S + E +
Sbjct: 202 SIG---ENQVEVMVEEKTTESQEETVVMS---------LKNGQISSEEPKQEEEREQGSD 249
Query: 362 PELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGS 421
E + + D E + A LEA ++A + + A +EA K +
Sbjct: 250 EISHHEKMEEEDKER------AEAERARLEAEERERIKAEQDKKI-ADERARIEAEEKAA 302
Query: 422 AEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALI 481
A+ +E + +E M + + + E A + + ++ K++ ++Q +
Sbjct: 303 AQ--ERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI- 359
Query: 482 PIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYK 541
K+ E + + + E N+Q+++ I + + K
Sbjct: 360 ---KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK 416
Query: 542 IMPIQHTLSVQSASSTVKKKKE-------------TVSKTTNRCEALSQRHMIYEESGNK 588
+ + + ++ +KK+ E K T + E + + ++ +
Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476
Query: 589 STAGIMNAEAA-TKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAE 647
M+ + T++ ++ + + E R + V K + A + G+
Sbjct: 477 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 536
Query: 648 DHLKLKDGQQQNETKKKKGWLDQEDQEAPLQ------KGDAKIKAQEEADKRKKEHERIM 701
+ L+ + G+ ++E +K L Q+ QEA L+ K + + K EE ++R+K+ E
Sbjct: 537 EELRRRRGETESEEFEK---LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEAD- 592
Query: 702 LQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHD 739
+ L+E E+++ EEI +R + K+ E D
Sbjct: 593 -RKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSD 629
Score = 43.1 bits (100), Expect = 0.001
Identities = 137/709 (19%), Positives = 269/709 (37%), Gaps = 107/709 (15%)
Query: 106 MEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWS 165
M++ +R+ + R++K E+ R+ AE +Q+++ +E+ ERRR A + ++
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAAR------ERRRRARQERLRQKQ 54
Query: 166 WGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLN 225
S ++ N +++ ++ + T+ + A +A+R+
Sbjct: 55 EEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARRE---------E 105
Query: 226 RRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQT 285
RR L + ++ Q E P +T + +++P R+ +D + + ++
Sbjct: 106 RRQKRLQEALER-QKEFDPTITDAS------LSLPSRRMQNDTAEN---ETTEKEEKSES 155
Query: 286 KVEESPLEKVETPPKASV-----DAPPQVNVEVFCNTSMEASPKAG-VGMAP-EVSTDSF 338
+ E +E+ ET K+ DA + E PK G +G EV +
Sbjct: 156 RQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEK 215
Query: 339 PVVSVDVSPVVSTYDSEMSMD----------ASPELSI-EALPKVD----------LETV 377
S + + V+S + ++S + S E+S E + + D LE
Sbjct: 216 TTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAE 275
Query: 378 PKVSI-------VASPEASLEAPPEVSL-----------EALPEVSVEAAPEGS-LEAPP 418
+ I +A A +EA + + E + E AA E ++
Sbjct: 276 ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE 335
Query: 419 KGSAEVAP--KESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMD 476
K +AE KE K + +E E A + A E K + + K+ E
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Query: 477 KQAL--IPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSP 534
K A+ I +++ E KW + + +Q ++ Q
Sbjct: 396 KHAMQETKIKGEKVEQKIEG-KWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQED 454
Query: 535 QTSFPYKIMPIQHTLSVQSASSTVK-----KKKETVSKTTN---RCEALSQRHMIYEESG 586
+ +F + + + + VK KK T K+ N L + G
Sbjct: 455 KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 514
Query: 587 NKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQA 646
+++ AE A ++ R +R E E + E+++Q+ Q
Sbjct: 515 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQK---------------QQ 559
Query: 647 EDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQ 706
E L+L++ +++ E ++K L++E+Q ++ D K++ +EE + K+E ER + +
Sbjct: 560 EAALELEELKKKREERRKV--LEEEEQRRKQEEADRKLREEEEKRRLKEEIER---RRAE 614
Query: 707 ERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDS 755
+R+K E+ + +K + SS I E AE N+ K S
Sbjct: 615 AAEKRQKMPEDGLSDDKKP--FKCFTPKGSSLKIEERAEFLNKSVQKSS 661
Score = 43.1 bits (100), Expect = 0.001
Identities = 25/93 (26%), Positives = 53/93 (56%), Gaps = 7/93 (7%)
Query: 56 PVIDGSMLKNDIKQRLARERREE----KRRQQDANKETQLLEK---ERKTKLQYEKQMEE 108
P ++ ++++R EE K++QQ+A E + L+K ER+ L+ E+Q +
Sbjct: 528 PQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRK 587
Query: 109 RQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEK 141
++ ++ +E+EE+RR+ E +R + + A+K +
Sbjct: 588 QEEADRKLREEEEKRRLKEEIERRRAEAAEKRQ 620
Score = 42.7 bits (99), Expect = 0.001
Identities = 43/179 (24%), Positives = 88/179 (49%), Gaps = 18/179 (10%)
Query: 72 ARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERK---EKEEQRRIAAE 128
A +R EE RR++ E++ EK ++ + + ++EE ++K +ER+ E+EEQRR E
Sbjct: 532 AGKRLEELRRRR-GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE 590
Query: 129 EKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEK 188
R ++E +K + L +ERRR ++++ G + K + +S K
Sbjct: 591 ADRKLREEEEKRR----LKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSL-K 645
Query: 189 LEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVT 247
+E+ L + + SS G++++ +++ +++ DS L T + + + T
Sbjct: 646 IEERAEFLNKSVQKSS-GVKST--------HQAAIVSKIDSRLEQYTSAIEGTKSAKPT 695
Score = 41.2 bits (95), Expect = 0.004
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 22/155 (14%)
Query: 605 ELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKK 664
E R+A ++ + +EEE RE ++ ++ + +E GQ D +++ QN
Sbjct: 21 EAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV---NAQNSV--- 74
Query: 665 KGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERK-KRIEEIMKRTR 723
D+EA + +++ +EA L+ L R ER+ KR++E ++R +
Sbjct: 75 ------PDEEAKTTTTNTQVEGDDEA---------AFLERLARREERRQKRLQEALERQK 119
Query: 724 KTDVNASKVTETSSHDIYEEAEADNEESDKDSLNE 758
+ D + + + + A+NE ++K+ +E
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSE 154
Score = 41.2 bits (95), Expect = 0.004
Identities = 45/167 (26%), Positives = 81/167 (48%), Gaps = 13/167 (7%)
Query: 63 LKNDIKQRLARERREEKRRQQ--DANKETQLLEKERKTKLQYEK---QMEERQRKLKERK 117
LKN Q + E ++E+ R+Q D + +E+E K + + E+ + EER+R E+
Sbjct: 228 LKNG--QISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQD 285
Query: 118 EK--EEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSE 175
+K +E+ RI AEEK ++ ++E R E +R A++ Q+ + +A
Sbjct: 286 KKIADERARIEAEEKAAAQERERREAEERERMRE-EEKRAAEERQRIKEEEKRAAEERQR 344
Query: 176 SKTANKRSASTE---KLEQGTSALIRQMPLSSAGLQNSVAKRKTDKE 219
K KR+A K E+ +A RQ + + V ++K +K+
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ 391
Score = 38.5 bits (88), Expect = 0.028
Identities = 33/150 (22%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 612 EQREKEEEERQREEMQQ-RVIKKS--KDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWL 668
E+ EK E ++R E+++ + KS K+ ++A + ED K+ +++ E K K+G +
Sbjct: 148 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKED----KEKEEEEEEKPKRGSI 203
Query: 669 DQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVN 728
+ E ++ + ++QEE ++ +I + ++ ER++ +EI + + +
Sbjct: 204 GENQVEVMVE--EKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261
Query: 729 ASKVTETSSHDIYEEAEADNEESDKDSLNE 758
+ + EE E E DK +E
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADE 291
Score = 37.7 bits (86), Expect = 0.047
Identities = 47/237 (19%), Positives = 99/237 (41%), Gaps = 28/237 (11%)
Query: 615 EKEEEERQREEMQQRV---------------IKKSKDMAKEAVGGQAEDHLKLKDGQQQN 659
E+ ++E +RE+ + ++++ A+E +AE K+ D + +
Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARI 295
Query: 660 ETKKKKGWLDQEDQEA-PLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEI 718
E ++K ++E +EA ++ + K E +R KE E+ + Q E +KR E
Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 355
Query: 719 MKRTRKTDVNASKVTETSSHDIYEEAEADNEESDK--DSLNEMFPSAILNGTGSPTKFKM 776
+R ++ + A++ + + + E+A+ + ++ +K + + G K +
Sbjct: 356 RQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEG 415
Query: 777 PFNNAKKMTH--------KLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQE 825
+ N KK K E GT K K D F+++ +KD I++
Sbjct: 416 KWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK--LQEDKPTFKKEEIKDEKIKK 470
Score = 35.8 bits (81), Expect = 0.18
Identities = 43/218 (19%), Positives = 93/218 (42%), Gaps = 33/218 (15%)
Query: 559 KKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEE 618
K+++E++ + T++ E +Q + EE+ +T + + L L R
Sbjct: 53 KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLAR---------- 102
Query: 619 EERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQ 678
REE +Q+ ++++ + KE + L L + QN+T + + +E E+ +
Sbjct: 103 ----REERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158
Query: 679 K------------------GDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMK 720
+ DA+ +E+ +K ++E E+ ++ E E+ +
Sbjct: 159 RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTE 218
Query: 721 RTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNE 758
+T V + K + SS + +E E + + SD+ S +E
Sbjct: 219 SQEETVVMSLKNGQISSEEPKQEEERE-QGSDEISHHE 255
Score = 35.0 bits (79), Expect = 0.30
Identities = 43/228 (18%), Positives = 87/228 (38%), Gaps = 40/228 (17%)
Query: 26 AANEIAKERRKQDVVNRVATHSSNIRSTFKPVI-DGSM------LKNDIKQRLARERREE 78
A E +++R Q+ + R + F P I D S+ ++ND + E+ E+
Sbjct: 101 ARREERRQKRLQEALER--------QKEFDPTITDASLSLPSRRMQNDTAENETTEKEEK 152
Query: 79 KRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQ 138
+Q+ ++ E E TK + + + KE KEKEE+ EEK + +
Sbjct: 153 SESRQE---RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE----EEKPKRGSIGE 205
Query: 139 KEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIR 198
+ + +T E + M+ + +++ E+ EQG+ +
Sbjct: 206 NQVEVMVEEKTTESQEET------------VVMSLKNGQISSEEPKQEEEREQGSDEISH 253
Query: 199 QMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRV 246
+ K + + ER+ + + DK+ A+ + R+
Sbjct: 254 HEKMEEED------KERAEAERARLEAEERERIKAEQDKKIADERARI 295
>gi|21389509 KPL2 protein isoform 2 [Homo sapiens]
Length = 514
Score = 55.8 bits (133), Expect = 2e-07
Identities = 54/201 (26%), Positives = 96/201 (47%), Gaps = 38/201 (18%)
Query: 548 TLSVQSASSTVKKKKET--VSKTTNRCEALSQRHMIYEESGNKS--------TAGIMNAE 597
TL A +KKKKE V+ + EAL ++ + +ES +K+ T ++N
Sbjct: 225 TLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTY 284
Query: 598 AATKILTELRR------LAREQREK---------------EEEERQREEMQQRVIKKSKD 636
+ + + ++++ AREQREK +EE + E++ R++++S+
Sbjct: 285 SDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQ 344
Query: 637 MAKEAVGGQAEDHLKLKDGQ------QQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEA 690
+ AV H K Q +Q+E ++ K + D D+EA L K AKI +E+
Sbjct: 345 ERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAK-QAKIDFEEQF 403
Query: 691 DKRKKEHERIMLQNLQERLER 711
K K+ H++I ++ Q R E+
Sbjct: 404 LKEKRFHDQIAVERAQARYEK 424
>gi|145699133 KPL2 protein isoform 1 [Homo sapiens]
Length = 1822
Score = 55.8 bits (133), Expect = 2e-07
Identities = 54/201 (26%), Positives = 96/201 (47%), Gaps = 38/201 (18%)
Query: 548 TLSVQSASSTVKKKKET--VSKTTNRCEALSQRHMIYEESGNKS--------TAGIMNAE 597
TL A +KKKKE V+ + EAL ++ + +ES +K+ T ++N
Sbjct: 225 TLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTY 284
Query: 598 AATKILTELRR------LAREQREK---------------EEEERQREEMQQRVIKKSKD 636
+ + + ++++ AREQREK +EE + E++ R++++S+
Sbjct: 285 SDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQ 344
Query: 637 MAKEAVGGQAEDHLKLKDGQ------QQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEA 690
+ AV H K Q +Q+E ++ K + D D+EA L K AKI +E+
Sbjct: 345 ERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAK-QAKIDFEEQF 403
Query: 691 DKRKKEHERIMLQNLQERLER 711
K K+ H++I ++ Q R E+
Sbjct: 404 LKEKRFHDQIAVERAQARYEK 424
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 54.3 bits (129), Expect = 5e-07
Identities = 44/197 (22%), Positives = 91/197 (46%), Gaps = 16/197 (8%)
Query: 561 KKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEE- 619
K++ +S+ ++ ++ + EE G K E + + + RR +RE+E E
Sbjct: 273 KRDLISREISKFRDTHKK--LEEEKGKK--------EKERQEIEKERRERERERERERER 322
Query: 620 -ERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQ 678
ER+RE ++R +K K+ +E + D K +D + E + + D+
Sbjct: 323 REREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS 382
Query: 679 KGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSH 738
+ K + +E +R++E ER + +ER ER++ E +R R+ + + + E
Sbjct: 383 RSREKSRDRERERERERERER---ERERER-EREREREREREREREREKDKKRDREEDEE 438
Query: 739 DIYEEAEADNEESDKDS 755
D YE + + + +K++
Sbjct: 439 DAYERRKLERKLREKEA 455
Score = 50.4 bits (119), Expect = 7e-06
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 33/219 (15%)
Query: 28 NEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERREEKRRQQDANK 87
N I E K+D+++R S R T K +L E+ ++++ +Q+ K
Sbjct: 265 NAIEMEEDKRDLISR---EISKFRDTHK--------------KLEEEKGKKEKERQEIEK 307
Query: 88 ETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILY 147
E + E+ER+ + + ++ ER+R+ + KEKE +R E+ +D
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERE---RERDRDRD------------ 352
Query: 148 RTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGL 207
RT ER R D + + S+ N + + ++S E+ + R+
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERE 412
Query: 208 QNSVAKRKTDKERSSSLNR-RDSNLHSSTDKEQAERKPR 245
+ +R+ ++ER R R+ + + ++ + ERK R
Sbjct: 413 REREREREREREREKDKKRDREEDEEDAYERRKLERKLR 451
Score = 45.1 bits (105), Expect = 3e-04
Identities = 39/180 (21%), Positives = 83/180 (46%), Gaps = 16/180 (8%)
Query: 73 RERREEKRRQQDANKE-------TQLLEKERKTKLQYEKQME-ERQRKLKERKEKEEQRR 124
R+R ++ R D NK+ ++ E+ER+ + + E++ E ER+R+ + +E+E +R
Sbjct: 365 RDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERE 424
Query: 125 IAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSA 184
++KR ++++ + L R L + A YQ++ +W E K +
Sbjct: 425 REKDKKRDREEDEEDAYERRKLERKLREKEAA--YQERLKNW-----EIRERKKTREYEK 477
Query: 185 STEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDK-ERSSSLNRRDSNLHSSTDKEQAERK 243
E+ E+ + ++ L++ R K R S+L +R + + ++ +RK
Sbjct: 478 EAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRK 537
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/195 (21%), Positives = 84/195 (43%), Gaps = 21/195 (10%)
Query: 72 ARERREEKRRQQDANKETQL-----LEKERKTKLQYEKQMEERQRKLKERKEKEEQ--RR 124
+RE+ ++ R+++ +E + E+ER+ + + E++ E + K ++R+E EE R
Sbjct: 384 SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Query: 125 IAAEEKRHQKDEAQKEKFTAILYR----TLERRRLADDYQQKRWSWGGSAMANSESKTAN 180
E K +K+ A +E+ R T E + A+ +++R A E
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503
Query: 181 KRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRR---------DSNL 231
K +G SAL +++ ++ RK +KE + +R D+ L
Sbjct: 504 DDDRDDPKYYRG-SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAEL 562
Query: 232 HSSTDKEQAERKPRV 246
+ + R+P++
Sbjct: 563 QRMEQEAERRRQPQI 577
Score = 40.0 bits (92), Expect = 0.009
Identities = 62/297 (20%), Positives = 116/297 (39%), Gaps = 35/297 (11%)
Query: 73 RERREEKRRQQDANKETQLLEKERKTKLQYEKQMEER---QRKLKERK----------EK 119
RER E+ R+++ +E + + +++ + + E+ ER +RKL+E++ E
Sbjct: 407 REREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI 466
Query: 120 EEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMA-----NS 174
E+++ EK +++E ++ + R E DD + + GSA+
Sbjct: 467 RERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 526
Query: 175 ESKTANKRSASTEK--LEQGTSALIRQ-MPLSSAGLQNSVAKRKTDKERSSSLNRRDSNL 231
+ A++R EK LE+ L+ + P A LQ +++ ++ R + + +
Sbjct: 527 KEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR--MEQEAERRRQPQIKQEPESE 584
Query: 232 HSSTDKEQAERKPRVTGVTNYVMQYVTVPLRK-CTSDELRAVMFPMSTM----KIPPQTK 286
+K++ E K M+ P +K C LR + S P T
Sbjct: 585 EEEEEKQEKEEK------REEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTP 638
Query: 287 VEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSV 343
+ESP + P + S D S++ G V PV SV
Sbjct: 639 GDESPC-GIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSV 694
Score = 36.6 bits (83), Expect = 0.10
Identities = 41/195 (21%), Positives = 76/195 (38%), Gaps = 43/195 (22%)
Query: 607 RRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNET---KK 663
R RE+ + E ER+RE ++R +K K +E A + KL+ ++ E ++
Sbjct: 401 REREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQER 460
Query: 664 KKGWLDQE-------DQEAPLQ------------------------KGDAKIKAQEEADK 692
K W +E ++EA + + D K K
Sbjct: 461 LKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQK 520
Query: 693 RKKEHERIMLQNLQERLERKKRIEEIMKRT-----RKTDVNASKVTETSSH----DIYEE 743
R ++ E+ M + ++R K+ +EEI +R D ++ + + I +E
Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQE 580
Query: 744 AEADNEESDKDSLNE 758
E++ EE +K E
Sbjct: 581 PESEEEEEEKQEKEE 595
Score = 34.3 bits (77), Expect = 0.52
Identities = 34/198 (17%), Positives = 83/198 (41%), Gaps = 41/198 (20%)
Query: 605 ELRRLAREQREKEEEER-----------QREEMQQRVIKKSKDMAKEAVGGQAEDHLKLK 653
E R +RE+E++++ +R ++++++ +K + + + K +
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTR 473
Query: 654 DGQQQ------------NETKKKKGWLDQEDQE---------APLQKGDAKIKAQEEADK 692
+ +++ E K+ K +L+ D + + LQK + + EAD+
Sbjct: 474 EYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADE 533
Query: 693 RKKEHERIMLQNLQERL---------ERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEE 743
R ++ E+ L+ +++RL +R+E+ +R R+ + +E + E+
Sbjct: 534 RDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEK 593
Query: 744 AEADNEESDKDSLNEMFP 761
E E +++ E P
Sbjct: 594 EEKREEPMEEEEEPEQKP 611
Score = 32.3 bits (72), Expect = 2.0
Identities = 23/87 (26%), Positives = 47/87 (54%), Gaps = 18/87 (20%)
Query: 67 IKQRLARERREEKRRQQDANKETQLLEKERK-----------TKLQYEKQMEERQRK--L 113
+++RL +E + ++D +E + LE+ R+ +LQ +Q ER+R+ +
Sbjct: 518 LQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQI 577
Query: 114 KERKEKEEQRRIAAEEKRHQKDEAQKE 140
K+ E EE+ EE++ +K+E ++E
Sbjct: 578 KQEPESEEE-----EEEKQEKEEKREE 599
Score = 31.2 bits (69), Expect = 4.4
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 5/62 (8%)
Query: 66 DIKQRLARERR-----EEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKE 120
+I+QRL E E +R +Q+A + Q K+ + E++ +E++ K +E E+E
Sbjct: 545 EIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604
Query: 121 EQ 122
E+
Sbjct: 605 EE 606
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 53.9 bits (128), Expect = 6e-07
Identities = 52/243 (21%), Positives = 118/243 (48%), Gaps = 19/243 (7%)
Query: 16 LRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRL--AR 73
LR + ++ E ++RR+++ + R + R + + + + +Q+ A
Sbjct: 755 LRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 814
Query: 74 ERREEKRRQQDAN-KETQLLEKERKTKLQYEKQMEERQRKLKERKEK--EEQRRIAAEEK 130
R EE+RR+++ K+ +LL K+ + ++ ++ EE QR+L+E + + EE R+
Sbjct: 815 RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARL----- 869
Query: 131 RHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKR--SASTEK 188
RH+++E ++++ + L R+R QQ++ + + + A + S+ST
Sbjct: 870 RHEEEERKRKELEVQRQKELMRQR-----QQQQEALRRLQQQQQQQQLAQMKLPSSSTWG 924
Query: 189 LEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTG 248
+ T+A Q LS A +Q +R +++ R+ L + ++Q +++ +++G
Sbjct: 925 QQSNTTACQSQATLSLAEIQKLEEER--ERQLREEQRRQQRELMKALQQQQQQQQQKLSG 982
Query: 249 VTN 251
N
Sbjct: 983 WGN 985
Score = 48.5 bits (114), Expect = 3e-05
Identities = 33/180 (18%), Positives = 88/180 (48%), Gaps = 12/180 (6%)
Query: 64 KNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQR 123
+ + + R RE E KR+++ ++ ++L ++++ + + ++ E +RK +E ++ ++
Sbjct: 735 RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQ 794
Query: 124 RIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRS 183
IA +R +++ Q+E+ R LE RR ++ ++K+ + + + A K +
Sbjct: 795 EIALRRQREEEERQQQEE----ALRRLEERRREEEERRKQ-----EELLRKQEEEAAKWA 845
Query: 184 ASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERK 243
E+ ++ +M +A L++ +R K + + R+ + +++A R+
Sbjct: 846 REEEEAQRRLEENRLRMEEEAARLRHEEEER---KRKELEVQRQKELMRQRQQQQEALRR 902
Score = 46.2 bits (108), Expect = 1e-04
Identities = 39/170 (22%), Positives = 82/170 (48%), Gaps = 17/170 (10%)
Query: 599 ATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQ 658
A K+ E R + +EEE +++EE++++ +E + Q E+ K ++ ++
Sbjct: 728 AAKLEQERREAEMRAKREEEERKRQEELRRQ--------QEEILRRQQEEERKRREEEEL 779
Query: 659 NETKKKKGWLDQEDQEAPL--QKGDAKIKAQEEA-----DKRKKEHERIMLQNLQERLER 711
K+++ Q +QE L Q+ + + + QEEA ++R++E ER + L + E
Sbjct: 780 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 839
Query: 712 K--KRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEM 759
+ K E + R+ + N ++ E ++ +EE E +E + E+
Sbjct: 840 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL 889
Score = 39.7 bits (91), Expect = 0.012
Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 17/116 (14%)
Query: 85 ANKETQLLEKERKTKLQYEKQMEE--RQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKF 142
A ++ Q LEK + KL+ E++ E +R+ +ERK +EE RR E R Q++E +K +
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
Query: 143 TAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIR 198
L RR+ + +++R E + A +R E+ +Q AL R
Sbjct: 776 E----EELARRKQEEALRRQR-----------EQEIALRRQREEEERQQQEEALRR 816
Score = 39.7 bits (91), Expect = 0.012
Identities = 32/151 (21%), Positives = 73/151 (48%), Gaps = 8/151 (5%)
Query: 78 EKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEA 137
E+ +Q + K +L ++ R+ +++ +++ EER+R+ + R+++EE R EE+R +++E
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
Query: 138 Q--KEKFTAILYR------TLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKL 189
+ + K L R L R+R ++ QQ+ + E + K+ K
Sbjct: 778 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ 837
Query: 190 EQGTSALIRQMPLSSAGLQNSVAKRKTDKER 220
E+ + R+ + L+ + + + + R
Sbjct: 838 EEEAAKWAREEEEAQRRLEENRLRMEEEAAR 868
Score = 37.7 bits (86), Expect = 0.047
Identities = 38/182 (20%), Positives = 85/182 (46%), Gaps = 17/182 (9%)
Query: 583 EESGNKSTAGIMNAEAATKILTELRRLAREQREKEE-----EERQREEMQQRVIKKSKDM 637
EE + + + +I +R E++++EE EER+REE ++R K +++
Sbjct: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR---KQEEL 833
Query: 638 AKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKE- 696
++ Q E+ K +++ + + ++ L E++ A L+ + + K +E +R+KE
Sbjct: 834 LRK----QEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL 889
Query: 697 -HERIMLQNLQERLERKKRIEEIMKR---TRKTDVNASKVTETSSHDIYEEAEADNEESD 752
+R Q RL+++++ +++ + + T S T S AE E +
Sbjct: 890 MRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEE 949
Query: 753 KD 754
++
Sbjct: 950 RE 951
Score = 33.5 bits (75), Expect = 0.89
Identities = 38/149 (25%), Positives = 66/149 (44%), Gaps = 25/149 (16%)
Query: 558 VKKKKETVSKTTNRCEAL-------SQRHMIYEESGNKSTAGIMNAEAATKILTELRRLA 610
V+++KE + + + EAL Q+ + + + ST G + A + L LA
Sbjct: 883 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLS-LA 941
Query: 611 REQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQ 670
Q+ +EE ERQ E Q+R Q + +K QQQ + +K GW
Sbjct: 942 EIQKLEEERERQLREEQRR---------------QQRELMKALQQQQQQQQQKLSGW-GN 985
Query: 671 EDQEAPLQKGDAKIKAQEEADKRKKEHER 699
+ + K +I+ QEEA + +K+ ++
Sbjct: 986 VSKPSGTTKSLLEIQ-QEEARQMQKQQQQ 1013
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.121 0.320
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,633,872
Number of Sequences: 37866
Number of extensions: 1614038
Number of successful extensions: 37139
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 633
Number of HSP's successfully gapped in prelim test: 1283
Number of HSP's that attempted gapping in prelim test: 12176
Number of HSP's gapped (non-prelim): 13390
length of query: 876
length of database: 18,247,518
effective HSP length: 111
effective length of query: 765
effective length of database: 14,044,392
effective search space: 10743959880
effective search space used: 10743959880
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.