Search of human proteins with 145312251

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
         (1130 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145312251 EPH receptor A6 isoform a [Homo sapiens]                2328   0.0  
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi...  1290   0.0  
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...  1253   0.0  
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...  1243   0.0  
gi|4758282 ephrin receptor EphA7 [Homo sapiens]                      1219   0.0  
gi|4758280 ephrin receptor EphA4 [Homo sapiens]                      1218   0.0  
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi...  1147   0.0  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...  1082   0.0  
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...  1078   0.0  
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]            1070   0.0  
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]           1035   0.0  
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                      940   0.0  
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                  896   0.0  
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]                 870   0.0  
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                     743   0.0  
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]           729   0.0  
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi...   728   0.0  
gi|27734955 EPH receptor A6 isoform b [Homo sapiens]                  596   e-170
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi...   548   e-155
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]                308   1e-83
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]   216   1e-55
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]   216   1e-55
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]              210   7e-54
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]       207   5e-53
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...   206   8e-53
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...   206   8e-53
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]      204   5e-52
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]     203   9e-52
gi|4503787 fyn-related kinase [Homo sapiens]                          201   4e-51
gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]      197   4e-50

>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
          Length = 1130

 Score = 2328 bits (6032), Expect = 0.0
 Identities = 1130/1130 (100%), Positives = 1130/1130 (100%)

Query: 1    MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE 60
            MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE
Sbjct: 1    MQFPSPPAARSSPAPQAASSSEAAAPATGQPGPSCPVPGTSRRGRPGTPPAGRVEEEEEE 60

Query: 61   EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD 120
            EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD
Sbjct: 61   EEEDVDKDPHPTQNTCLRCRHFSLRERKREPRRTMGGCEVREFLLQFGFFLPLLTAWPGD 120

Query: 121  CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW 180
            CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW
Sbjct: 121  CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW 180

Query: 181  LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT 240
            LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT
Sbjct: 181  LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT 240

Query: 241  KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK 300
            KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK
Sbjct: 241  KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK 300

Query: 301  CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS 360
            CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS
Sbjct: 301  CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS 360

Query: 361  TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM 420
            TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM
Sbjct: 361  TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM 420

Query: 421  ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL 480
            ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL
Sbjct: 421  ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL 480

Query: 481  RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI 540
            RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI
Sbjct: 481  RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI 540

Query: 541  GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK 600
            GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK
Sbjct: 541  GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK 600

Query: 601  PATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILT 660
            PATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILT
Sbjct: 601  PATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILT 660

Query: 661  LFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEI 720
            LFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEI
Sbjct: 661  LFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEI 720

Query: 721  DPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQ 780
            DPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQ
Sbjct: 721  DPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQ 780

Query: 781  FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRP 840
            FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRP
Sbjct: 781  FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRP 840

Query: 841  VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV 900
            VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV
Sbjct: 841  VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV 900

Query: 901  NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM 960
            NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM
Sbjct: 901  NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM 960

Query: 961  WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDI 1020
            WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDI
Sbjct: 961  WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDI 1020

Query: 1021 VSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG 1080
            VSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG
Sbjct: 1021 VSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG 1080

Query: 1081 FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV 1130
            FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
Sbjct: 1081 FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV 1130


>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapiens]
          Length = 983

 Score = 1290 bits (3339), Expect = 0.0
 Identities = 621/996 (62%), Positives = 771/996 (77%), Gaps = 55/996 (5%)

Query: 126  NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185
            +N+V LLD+ T+ GELGW +YP +GW+ I+ +DEH  PI TYQVCNVM+ +QNNWLRTNW
Sbjct: 27   SNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNW 86

Query: 186  ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245
            + R++AQKIYVE+KFTLRDCNSIP VLGTCKETFNL+YMESD+ HG+KF+ +Q+TKIDTI
Sbjct: 87   VPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTI 146

Query: 246  AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305
            AADESFTQMDLGDRILKLNTEIREVGP+ +KGFYLAFQD+GAC+ALVSVRV++KKCPFTV
Sbjct: 147  AADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTV 206

Query: 306  RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365
            +NLAMFPDT+P +DS SLVEVRGSCV +++E D P++YC  +G+WLVP+G+C C+ GYEE
Sbjct: 207  KNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEE 265

Query: 366  IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
                C ACRPGFYKA  GN KC+KCPPHS T  + +  C+CE  YFRA+KDPPSMACTRP
Sbjct: 266  RGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRP 325

Query: 426  PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
            PS+PRNV+ NINET++IL+WS P DTGGRKD+T+++ICKKCG +  QCE C   +RF+PR
Sbjct: 326  PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385

Query: 486  HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
              GL N +V V D ++H NYTFEI+A+NGVSELS  P+ F A+++TT+Q APS +  ++K
Sbjct: 386  QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKK 445

Query: 546  DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
            D  S+NSI+LSWQ P   NG ILDYE+KYYEK+ ++ +Y+  R++  +V I+ LKP T Y
Sbjct: 446  DRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIY 505

Query: 606  VFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLI 665
            VF IR RTA GY   S+KFEFET  ++  ++ E  Q+++IA +A     LL +  + +++
Sbjct: 506  VFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTV--VIYVL 563

Query: 666  TGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRI 725
             GR   Y K+K  ++EKR  H  NGHL+ PG++TY+DP TYEDP+ AVHEFAKE+D + I
Sbjct: 564  IGRFCGY-KSKHGADEKRL-HFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNI 621

Query: 726  RIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPN 785
             I++V+GAGEFGEVCSGRLK P K+EI VAIKTLK G+ ++QRRDFL EASIMGQFDHPN
Sbjct: 622  SIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 681

Query: 786  IIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVV 845
            IIRLEGVVTK                                           +PVMIV 
Sbjct: 682  IIRLEGVVTK------------------------------------------SKPVMIVT 699

Query: 846  EYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLV 905
            EYMENGSLDSFLRKHD  FTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNIL+NSNLV
Sbjct: 700  EYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLV 759

Query: 906  CKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMS 965
            CKVSDFGLSRVLEDDPEAAYTT GGKIPIRWT+PEAIAYRKF+SASD WSYGIV+WEVMS
Sbjct: 760  CKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMS 819

Query: 966  YGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLD 1025
            YGERPYWEMSNQDVI +++EGYRLP PM CPA+L+QLML CWQK+RN+RPKF  IVS LD
Sbjct: 820  YGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879

Query: 1026 KLIRNPSALHTLVE-----DILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG 1080
            KLIRNP +L  +         L++ +S  ++     F T GDWL+ +     K  F    
Sbjct: 880  KLIRNPGSLKIITSAAARPSNLLLDQSNVDI---TTFRTTGDWLNGVWTAHCKEIFTGVE 936

Query: 1081 FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTL 1116
            +++ D I+++S DD++++GV ++G Q++I+SSI+ L
Sbjct: 937  YSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKAL 972


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
          Length = 1015

 Score = 1253 bits (3242), Expect = 0.0
 Identities = 605/1002 (60%), Positives = 766/1002 (76%), Gaps = 54/1002 (5%)

Query: 126  NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185
            +N+V LLD+ TV+G+LGW  +P NGW+ I E+DE+  PIHTYQVC VME NQNNWL T+W
Sbjct: 58   SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSW 117

Query: 186  ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245
            IS + A +I++E+KFTLRDCNS+P  LGTCKETFN++Y ESD+ +G   K NQY KIDTI
Sbjct: 118  ISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTI 177

Query: 246  AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305
            AADESFT++DLGDR++KLNTE+R+VGP+ +KGFYLAFQD+GACIALVSVRV+YKKCP  V
Sbjct: 178  AADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVV 237

Query: 306  RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365
            R+LA+FPDTI   DSS L+EV GSCV  +   + PK++C A+G+WLVP+G+C+C  GYEE
Sbjct: 238  RHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEE 297

Query: 366  IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
              G+C  CRPGF+KA      C KCPPHS T+ EA++ C CEK YFR E DPP+MACTRP
Sbjct: 298  KNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRP 357

Query: 426  PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
            PSAPRN + N+NET++ LEW PP+DTGGRKD++Y + CKKC      CE+CGG +R++PR
Sbjct: 358  PSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPR 417

Query: 486  HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
             +GL N SV+++D ++H NYTFEIEA+NGVS+LS   + + ++ VTT+Q APS +  V+K
Sbjct: 418  QSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKK 477

Query: 546  DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
               ++NSI+LSWQ P   NG IL+YEIKY+EK+ E  +Y+  +SK  ++   GLKPA+ Y
Sbjct: 478  GKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTIIKSKETTITAEGLKPASVY 536

Query: 606  VFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLI 665
            VF IR RTA GY  +S++FEFET       +++Q QI VIA +   G  LL ++ +  L+
Sbjct: 537  VFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIAVSVTVGVILLAVV-IGVLL 594

Query: 666  TGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRI 725
            +GR   Y KAK   EE++  H  NGH++ PG++TYIDP TYEDP+ AVHEFAKEI+ S I
Sbjct: 595  SGRRCGYSKAKQDPEEEKM-HFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCI 653

Query: 726  RIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPN 785
             IERVIGAGEFGEVCSGRLK PGKRE+PVAIKTLK G+ ++QRRDFL EASIMGQFDHPN
Sbjct: 654  TIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 713

Query: 786  IIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVV 845
            II LEGVVTK                                           +PVMIV 
Sbjct: 714  IIHLEGVVTK------------------------------------------SKPVMIVT 731

Query: 846  EYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLV 905
            EYMENGSLD+FL+K+DG FTVIQLVGMLRGI++GMKYLSDMGYVHRDLAARNIL+NSNLV
Sbjct: 732  EYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLV 791

Query: 906  CKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMS 965
            CKVSDFGLSRVLEDDPEAAYTT GGKIPIRWTAPEAIA+RKF+SASD WSYGIVMWEV+S
Sbjct: 792  CKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVS 851

Query: 966  YGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLD 1025
            YGERPYWEM+NQDVI ++EEGYRLP+PM CPA+L+QLML CWQKERN RPKF +IV+ LD
Sbjct: 852  YGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 911

Query: 1026 KLIRNPSALHTLVE-----DILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAG 1080
            KLIRNPS+L TLV        L+   SP     Y    +VG+WL++IKMG+Y   F+  G
Sbjct: 912  KLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYR---SVGEWLEAIKMGRYTEIFMENG 968

Query: 1081 FTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMH 1122
            +++ D +++++++D+RR+GV L+GHQ++I++S+Q +++ +++
Sbjct: 969  YSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVN 1010


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
          Length = 1037

 Score = 1243 bits (3217), Expect = 0.0
 Identities = 606/1024 (59%), Positives = 767/1024 (74%), Gaps = 76/1024 (7%)

Query: 126  NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185
            +N+V LLD+ TV+G+LGW  +P NGW+ I E+DE+  PIHTYQVC VME NQNNWL T+W
Sbjct: 58   SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSW 117

Query: 186  ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245
            IS + A +I++E+KFTLRDCNS+P  LGTCKETFN++Y ESD+ +G   K NQY KIDTI
Sbjct: 118  ISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTI 177

Query: 246  AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305
            AADESFT++DLGDR++KLNTE+R+VGP+ +KGFYLAFQD+GACIALVSVRV+YKKCP  V
Sbjct: 178  AADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVV 237

Query: 306  RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365
            R+LA+FPDTI   DSS L+EV GSCV  +   + PK++C A+G+WLVP+G+C+C  GYEE
Sbjct: 238  RHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEE 297

Query: 366  IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
              G+C  CRPGF+KA      C KCPPHS T+ EA++ C CEK YFR E DPP+MACTRP
Sbjct: 298  KNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRP 357

Query: 426  PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
            PSAPRN + N+NET++ LEW PP+DTGGRKD++Y + CKKC      CE+CGG +R++PR
Sbjct: 358  PSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPR 417

Query: 486  HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
             +GL N SV+++D ++H NYTFEIEA+NGVS+LS   + + ++ VTT+Q APS +  V+K
Sbjct: 418  QSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKK 477

Query: 546  DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
               ++NSI+LSWQ P   NG IL+YEIKY+EK+ E  +Y+  +SK  ++   GLKPA+ Y
Sbjct: 478  GKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTIIKSKETTITAEGLKPASVY 536

Query: 606  VFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLI 665
            VF IR RTA GY  +S++FEFET       +++Q QI VIA +   G  LL ++ +  L+
Sbjct: 537  VFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIAVSVTVGVILLAVV-IGVLL 594

Query: 666  TGRC-------------------QW---YIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDP 703
            +G C                    W   Y KAK   EE++  H  NGH++ PG++TYIDP
Sbjct: 595  SGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKM-HFHNGHIKLPGVRTYIDP 653

Query: 704  DTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGH 763
             TYEDP+ AVHEFAKEI+ S I IERVIGAGEFGEVCSGRLK PGKRE+PVAIKTLK G+
Sbjct: 654  HTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGY 713

Query: 764  MDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPH 823
             ++QRRDFL EASIMGQFDHPNII LEGVVTK                            
Sbjct: 714  TEKQRRDFLGEASIMGQFDHPNIIHLEGVVTK---------------------------- 745

Query: 824  PVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYL 883
                           +PVMIV EYMENGSLD+FL+K+DG FTVIQLVGMLRGI++GMKYL
Sbjct: 746  --------------SKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYL 791

Query: 884  SDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIA 943
            SDMGYVHRDLAARNIL+NSNLVCKVSDFGLSRVLEDDPEAAYTT GGKIPIRWTAPEAIA
Sbjct: 792  SDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA 851

Query: 944  YRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLM 1003
            +RKF+SASD WSYGIVMWEV+SYGERPYWEM+NQDVI ++EEGYRLP+PM CPA+L+QLM
Sbjct: 852  FRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLM 911

Query: 1004 LHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVE-----DILVMPESPGEVPEYPLFV 1058
            L CWQKERN RPKF +IV+ LDKLIRNPS+L TLV        L+   SP     Y    
Sbjct: 912  LDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYR--- 968

Query: 1059 TVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRL 1118
            +VG+WL++IKMG+Y   F+  G+++ D +++++++D+RR+GV L+GHQ++I++S+Q +++
Sbjct: 969  SVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKV 1028

Query: 1119 HMMH 1122
             +++
Sbjct: 1029 QLVN 1032


>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
          Length = 998

 Score = 1219 bits (3154), Expect = 0.0
 Identities = 586/1014 (57%), Positives = 746/1014 (73%), Gaps = 58/1014 (5%)

Query: 128  QVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWIS 187
            +V+LLD+     EL W + P NGW+ I+ +DE+  PI TYQVC VMEPNQNNWLRTNWIS
Sbjct: 32   EVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNWIS 91

Query: 188  RDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTIAA 247
            +  AQ+I+VE+KFTLRDCNS+P VLGTCKETFNL+Y E+D   G   + N Y KIDTIAA
Sbjct: 92   KGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDTIAA 151

Query: 248  DESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVRN 307
            DESFTQ DLG+R +KLNTE+RE+GP+ +KGFYLAFQD+GACIALVSV+V+YKKC   + N
Sbjct: 152  DESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIEN 211

Query: 308  LAMFPDTIPRVDSSSLVEVRGSCVKSAEER--DTPKLYCGADGDWLVPLGRCICSTGYEE 365
            LA+FPDT+   + SSLVEVRG+CV SAEE   + P+++C A+G+WLVP+G+CIC  GY++
Sbjct: 212  LAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAGYQQ 271

Query: 366  IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
               +C  C  GFYK+ + + +CS+CP HS +  E +S C+CE GY+RA  DPP +ACTRP
Sbjct: 272  KGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVACTRP 331

Query: 426  PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
            PSAP+N++FNIN+T + LEWSPP+D GGR D+TY ++CK+C  +  +C  CG  + ++P+
Sbjct: 332  PSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQ 391

Query: 486  HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
             TGL +N V V+D ++H NYTFE+EA+NGVS+LS S + F A+++TT Q APS +  V K
Sbjct: 392  QTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMK 451

Query: 546  DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
            +   Q S+ LSWQ P   NG I +YEIKYYEK+  + TYS+ ++K+ S  I  LKP T Y
Sbjct: 452  ERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPGTVY 511

Query: 606  VFHIRVRTATGYSGYSQKFEFETGDETSD-------MAAEQGQILVIATAAVGGFTLLVI 658
            VF IR  TA GY  YS + +  T +E +        +++EQ  +++IA  AV G  +LV 
Sbjct: 512  VFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTIILVF 571

Query: 659  LTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAK 718
            +   F+I  R   Y KA  + +E+        H +FPG KTYIDP+TYEDP+ AVH+FAK
Sbjct: 572  MVFGFIIGRRHCGYSKADQEGDEE-----LYFHFKFPGTKTYIDPETYEDPNRAVHQFAK 626

Query: 719  EIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIM 778
            E+D S I+IERVIGAGEFGEVCSGRLK PGKR++ VAIKTLK G+ ++QRRDFL EASIM
Sbjct: 627  ELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIM 686

Query: 779  GQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAG 838
            GQFDHPN++ LEGVVT+                                          G
Sbjct: 687  GQFDHPNVVHLEGVVTR------------------------------------------G 704

Query: 839  RPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNI 898
            +PVMIV+E+MENG+LD+FLRKHDG FTVIQLVGMLRGIA+GM+YL+DMGYVHRDLAARNI
Sbjct: 705  KPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNI 764

Query: 899  LVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGI 958
            LVNSNLVCKVSDFGLSRV+EDDPEA YTTTGGKIP+RWTAPEAI YRKF+SASD WSYGI
Sbjct: 765  LVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGI 824

Query: 959  VMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFT 1018
            VMWEVMSYGERPYW+MSNQDVI +IEEGYRLPAPM CPA LHQLML CWQKER  RPKF 
Sbjct: 825  VMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFE 884

Query: 1019 DIVSFLDKLIRNPSALHTLVEDIL--VMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNF 1076
             IV  LDK+IRNP++L T +      + P      P++  F +VG+WL +IKM +YK+NF
Sbjct: 885  QIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNF 944

Query: 1077 VAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV 1130
             AAG+ + + ++RM+I+D+  +G+ L+GHQ++I+SSIQT+R  M+H+   G  V
Sbjct: 945  TAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV 998


>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
          Length = 986

 Score = 1218 bits (3152), Expect = 0.0
 Identities = 602/1029 (58%), Positives = 746/1029 (72%), Gaps = 68/1029 (6%)

Query: 109  FFLPLLTAWPGDCSHVSN------NQVVLLDTTTVLGELGWKTYPLNG-WDAITEMDEHN 161
            F+  L +   G C  V+       N+V LLD+ +V GELGW   PL G W+ ++ MDE N
Sbjct: 5    FYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKN 64

Query: 162  RPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNL 221
             PI TYQVCNVMEP+QNNWLRT+WI+R+ AQ++Y+E+KFTLRDCNS+P V+GTCKETFNL
Sbjct: 65   TPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNL 124

Query: 222  FYMESDESHGIKFKPNQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLA 281
            +Y ESD       + NQ+ KIDTIAADESFTQ+D+GDRI+KLNTEIR+VGP+ +KGFYLA
Sbjct: 125  YYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLA 184

Query: 282  FQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPK 341
            FQD+GACIALVSVRVFYKKCP TVRNLA FPDTI   D+SSLVEVRGSCV ++EE+D PK
Sbjct: 185  FQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPK 244

Query: 342  LYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEAT 401
            +YCGADG+WLVP+G C+C+ G+EE  G C AC+ G+YKA + +  C+KCPPHS +  E  
Sbjct: 245  MYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGA 304

Query: 402  SVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSV 461
            + C C++G+FRA+ D  SM CTRPPSAP N++ N+NET++ LEWS P +TGGR+D++Y+V
Sbjct: 305  TSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNV 364

Query: 462  ICKKCGL-DTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSF 520
            +CKKCG  D S+C  CG G+ + P+  GL    V + D ++H NYTFEI A+NGVS+ + 
Sbjct: 365  VCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNP 424

Query: 521  SPKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHE 580
            +P    ++TVTT+Q APS I +V+    ++ S+AL+W  P   NG IL+YE+KYYEK+  
Sbjct: 425  NPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQN 484

Query: 581  QLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQG 640
            + +Y   R+ A +  I GL P T YVFH+R RTA GY  +S+  E  T    S +  +  
Sbjct: 485  ERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGA 544

Query: 641  QILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTY 700
               V+  +  G   L+VIL   F+I+ R   Y KAK +++E++  HL        G++TY
Sbjct: 545  NSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEK--HLNQ------GVRTY 596

Query: 701  IDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLK 760
            +DP TYEDP+ AV EFAKEID S I+IE+VIG GEFGEVCSGRLK PGKREI VAIKTLK
Sbjct: 597  VDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLK 656

Query: 761  GGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQ 820
             G+ D+QRRDFL EASIMGQFDHPNII LEGVVTK           C             
Sbjct: 657  AGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTK-----------C------------- 692

Query: 821  APHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGM 880
                              +PVMI+ EYMENGSLD+FLRK+DG FTVIQLVGMLRGI SGM
Sbjct: 693  ------------------KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGM 734

Query: 881  KYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPE 940
            KYLSDM YVHRDLAARNILVNSNLVCKVSDFG+SRVLEDDPEAAYTT GGKIPIRWTAPE
Sbjct: 735  KYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPE 794

Query: 941  AIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLH 1000
            AIAYRKF+SASD WSYGIVMWEVMSYGERPYW+MSNQDVI +IEEGYRLP PM CP +LH
Sbjct: 795  AIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALH 854

Query: 1001 QLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSAL------HTLVEDILVMPESPGEVPEY 1054
            QLML CWQKER+ RPKF  IV+ LDKLIRNP++L       +     L+ P S    PE+
Sbjct: 855  QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSS----PEF 910

Query: 1055 PLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQ 1114
               V+VGDWL +IKM +YK+NF AAG+TT + +  ++ +D+ RIG+  I HQ +I+SS+Q
Sbjct: 911  SAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQ 970

Query: 1115 TLRLHMMHI 1123
             +R  M  +
Sbjct: 971  AMRTQMQQM 979


>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
          Length = 1005

 Score = 1147 bits (2968), Expect = 0.0
 Identities = 557/1039 (53%), Positives = 723/1039 (69%), Gaps = 86/1039 (8%)

Query: 121  CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW 180
            C   +  +V LLDT+T+ G+ GW TYP +GWD+I E+DE  +PIHTYQVCNVM PNQNNW
Sbjct: 24   CVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNW 83

Query: 181  LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT 240
            LRT+W+ RD A+++Y E+KFTLRDCNS+P VLGTCKETFNL+Y+ESD   G   + +Q+ 
Sbjct: 84   LRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFL 143

Query: 241  KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK 300
            KIDTIAADESFT  DLG R LKLNTE+R VGP+ ++GFYLAFQDIGAC+A++S+R++YKK
Sbjct: 144  KIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKK 203

Query: 301  CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS 360
            CP  VRNLA F + +   DSSSLVEVRG CV+ +EERDTPK+YC A+G+WLVP+G+C+CS
Sbjct: 204  CPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCS 263

Query: 361  TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM 420
             GYEE   +C AC  GFYK+  G+  C++CPPHS +   A   C C+  Y+RA  DPPS 
Sbjct: 264  AGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323

Query: 421  ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL 480
            ACTRPPSAP N++ ++N T++ LEW+PP D GGR D+TY+ +C++C    S+CE CG G 
Sbjct: 324  ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383

Query: 481  RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLI 540
            RF+P+ T L+  S++V + ++H+NY+F IEA+NGVS+LS  P+    + +TT+Q APS +
Sbjct: 384  RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQV 443

Query: 541  GVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLK 600
             V+R++ A Q S++L WQ P   NG IL+YEIKYYEK+ E  +YS+ ++      ++GLK
Sbjct: 444  VVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLK 503

Query: 601  PATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILT 660
            P T+YVF +R RT+ G   +SQ  E ETG        +   I+ I    + G   LV+L 
Sbjct: 504  PGTRYVFQVRARTSAGCGRFSQAMEVETGKPRP--RYDTRTIVWICLTLITG---LVVLL 558

Query: 661  LFFLITGRCQWYIKAKMKSEEKRRNHLQNGHL-------------RFPGIKTYIDPDTYE 707
            L  +   R   Y KA   S+E++  H QNG               + P  + Y +P TYE
Sbjct: 559  LLLICKKRHCGYSKAFQDSDEEKM-HYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYE 617

Query: 708  DPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQ 767
            +P  A   F +EI+ SRI IE++IG+G+ GEVC GRL+ PG+R++PVAIK LK G+ +RQ
Sbjct: 618  EPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQ 677

Query: 768  RRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPG 827
            RRDFL EASIMGQFDHPNIIRLEGVVT+                                
Sbjct: 678  RRDFLSEASIMGQFDHPNIIRLEGVVTR-------------------------------- 705

Query: 828  GGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMG 887
                      GR  MIV EYMENGSLD+FLR HDG FT++QLVGMLRG+ +GM+YLSD+G
Sbjct: 706  ----------GRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLG 755

Query: 888  YVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKF 947
            YVHRDLAARN+LV+SNLVCKVSDFGLSRVLEDDP+AAYTTTGGKIPIRWTAPEAIA+R F
Sbjct: 756  YVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTF 815

Query: 948  SSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCW 1007
            SSASD WS+G+VMWEV++YGERPYW M+N+DVI S+EEGYRLPAPMGCP +LHQLML CW
Sbjct: 816  SSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCW 875

Query: 1008 QKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFV--------- 1058
             K+R  RP+F+ IVS LD LIR+P +L          P         P FV         
Sbjct: 876  HKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPP---------PAFVRSCFDLRGG 926

Query: 1059 -------TVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVS 1111
                   TVGDWLDSI+MG+Y+++F A G+++  ++ RM+  D+R +G+ L+GHQ++I+ 
Sbjct: 927  SGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILG 986

Query: 1112 SIQTLRLHMMHIQEKGFHV 1130
            SIQT+R  +   Q    H+
Sbjct: 987  SIQTMRAQLTSTQGPRRHL 1005


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapiens]
          Length = 987

 Score = 1082 bits (2798), Expect = 0.0
 Identities = 537/1006 (53%), Positives = 704/1006 (69%), Gaps = 57/1006 (5%)

Query: 131  LLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDA 190
            L+D+TT   ELGW  +P +GW+ ++  DE+   I TYQVCNV E +QNNWLRT +I R  
Sbjct: 23   LMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIRRRG 82

Query: 191  AQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPN----QYTKIDTIA 246
            A +I+VEMKF++RDC+SIP V G+CKETFNL+Y E+D     K  PN     + K+DTIA
Sbjct: 83   AHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVDTIA 142

Query: 247  ADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVR 306
            ADESF+Q+DLG R++K+NTE+R  GP+ R GFYLAFQD G C++L++VRVFY+KCP  ++
Sbjct: 143  ADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPRIIQ 202

Query: 307  NLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTP-KLYCGADGDWLVPLGRCICSTGYEE 365
            N A+F +T+   +S+SLV  RGSC+ +AEE D P KLYC  DG+WLVP+GRC+C  G+E 
Sbjct: 203  NGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEA 262

Query: 366  IEGS--CHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACT 423
            +E    C  C  G +KA  G+  C+ CP +S T  E  + C C  GY+RA+ DP  M CT
Sbjct: 263  VENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCT 322

Query: 424  RPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFI 483
              PSAP+ V+ ++NET+L+LEW+PP D+GGR+DL Y++ICK CG     C  CG  +++ 
Sbjct: 323  TIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYA 382

Query: 484  PRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELS-FSPKPFTAITVTTDQDAPSLIGV 542
            PR  GL    + + D ++H  YTFEI+A+NGV++ S FSP+ F ++ +TT+Q APS + +
Sbjct: 383  PRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQ-FASVNITTNQAAPSAVSI 441

Query: 543  VRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPA 602
            + +   + +SI LSW  P   NG ILDYE++YYEKE  +   ++ +S   +V + GLK  
Sbjct: 442  MHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAG 501

Query: 603  TKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLF 662
              YVF +R RT  GY  YS K  F+T  E     + Q ++ +I  ++  G   L+ + + 
Sbjct: 502  AIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVI 561

Query: 663  FLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDP 722
             ++  R + + +A  +  +K + H  +GH+  PG+K YIDP TYEDP+ AV EFAKEID 
Sbjct: 562  AIVCNRRRGFERADSEYTDKLQ-HYTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEIDI 619

Query: 723  SRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFD 782
            S ++IE+VIGAGEFGEVCSG LK PGKREI VAIKTLK G+ ++QRRDFL EASIMGQFD
Sbjct: 620  SCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFD 679

Query: 783  HPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVM 842
            HPN+I LEGVVTK +                                          PVM
Sbjct: 680  HPNVIHLEGVVTKST------------------------------------------PVM 697

Query: 843  IVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNS 902
            I+ E+MENGSLDSFLR++DG FTVIQLVGMLRGIA+GMKYL+DM YVHRDLAARNILVNS
Sbjct: 698  IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 757

Query: 903  NLVCKVSDFGLSRVLEDD-PEAAYTTT-GGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM 960
            NLVCKVSDFGLSR LEDD  +  YT+  GGKIPIRWTAPEAI YRKF+SASD WSYGIVM
Sbjct: 758  NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 817

Query: 961  WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDI 1020
            WEVMSYGERPYW+M+NQDVI +IE+ YRLP PM CP++LHQLML CWQK+RNHRPKF  I
Sbjct: 818  WEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQI 877

Query: 1021 VSFLDKLIRNPSALHTL--VEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVA 1078
            V+ LDK+IRNP++L  +  +   + +P     +P+Y  F TV +WL++IKMGQYK +F  
Sbjct: 878  VNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFAN 937

Query: 1079 AGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQ 1124
            AGFT+FD++S+M ++DI R+GV L GHQ++I++SIQ +R  M  IQ
Sbjct: 938  AGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQ 983


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sapiens]
          Length = 986

 Score = 1078 bits (2789), Expect = 0.0
 Identities = 537/1006 (53%), Positives = 704/1006 (69%), Gaps = 58/1006 (5%)

Query: 131  LLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDA 190
            L+D+TT   ELGW  +P +GW+ ++  DE+   I TYQVCNV E +QNNWLRT +I R  
Sbjct: 23   LMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIRRRG 82

Query: 191  AQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPN----QYTKIDTIA 246
            A +I+VEMKF++RDC+SIP V G+CKETFNL+Y E+D     K  PN     + K+DTIA
Sbjct: 83   AHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVDTIA 142

Query: 247  ADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVR 306
            ADESF+Q+DLG R++K+NTE+R  GP+ R GFYLAFQD G C++L++VRVFY+KCP  ++
Sbjct: 143  ADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPRIIQ 202

Query: 307  NLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTP-KLYCGADGDWLVPLGRCICSTGYEE 365
            N A+F +T+   +S+SLV  RGSC+ +AEE D P KLYC  DG+WLVP+GRC+C  G+E 
Sbjct: 203  NGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEA 262

Query: 366  IEGS--CHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACT 423
            +E    C  C  G +KA  G+  C+ CP +S T  E  + C C  GY+RA+ DP  M CT
Sbjct: 263  VENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCT 322

Query: 424  RPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFI 483
              PSAP+ V+ ++NET+L+LEW+PP D+GGR+DL Y++ICK CG     C  CG  +++ 
Sbjct: 323  TIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYA 382

Query: 484  PRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELS-FSPKPFTAITVTTDQDAPSLIGV 542
            PR  GL    + + D ++H  YTFEI+A+NGV++ S FSP+ F ++ +TT+Q APS + +
Sbjct: 383  PRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQ-FASVNITTNQAAPSAVSI 441

Query: 543  VRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPA 602
            + +   + +SI LSW  P   NG ILDYE++YYEKE  +   ++ +S   +V + GLK  
Sbjct: 442  MHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAG 501

Query: 603  TKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLF 662
              YVF +R RT  GY  YS K  F+T  E     + Q ++ +I  ++  G   L+ + + 
Sbjct: 502  AIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVI 561

Query: 663  FLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDP 722
             ++  R + + +A  +  +K + H  +GH+  PG+K YIDP TYEDP+ AV EFAKEID 
Sbjct: 562  AIVCNR-RGFERADSEYTDKLQ-HYTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEIDI 618

Query: 723  SRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFD 782
            S ++IE+VIGAGEFGEVCSG LK PGKREI VAIKTLK G+ ++QRRDFL EASIMGQFD
Sbjct: 619  SCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFD 678

Query: 783  HPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVM 842
            HPN+I LEGVVTK +                                          PVM
Sbjct: 679  HPNVIHLEGVVTKST------------------------------------------PVM 696

Query: 843  IVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNS 902
            I+ E+MENGSLDSFLR++DG FTVIQLVGMLRGIA+GMKYL+DM YVHRDLAARNILVNS
Sbjct: 697  IITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNS 756

Query: 903  NLVCKVSDFGLSRVLEDD-PEAAYTTT-GGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM 960
            NLVCKVSDFGLSR LEDD  +  YT+  GGKIPIRWTAPEAI YRKF+SASD WSYGIVM
Sbjct: 757  NLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVM 816

Query: 961  WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDI 1020
            WEVMSYGERPYW+M+NQDVI +IE+ YRLP PM CP++LHQLML CWQK+RNHRPKF  I
Sbjct: 817  WEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQI 876

Query: 1021 VSFLDKLIRNPSALHTL--VEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVA 1078
            V+ LDK+IRNP++L  +  +   + +P     +P+Y  F TV +WL++IKMGQYK +F  
Sbjct: 877  VNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFAN 936

Query: 1079 AGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQ 1124
            AGFT+FD++S+M ++DI R+GV L GHQ++I++SIQ +R  M  IQ
Sbjct: 937  AGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQ 982


>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
          Length = 984

 Score = 1070 bits (2766), Expect = 0.0
 Identities = 538/1010 (53%), Positives = 694/1010 (68%), Gaps = 57/1010 (5%)

Query: 122  SHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWL 181
            S V+  +  L+DT T   ELGW   P +GW+ ++  DE+   I TYQVCNV EPNQNNWL
Sbjct: 13   SAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWL 72

Query: 182  RTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIK----FKPN 237
             T +I+R  A +IY EM+FT+RDC+S+P V G+CKETFNL+Y E+D     K    +   
Sbjct: 73   LTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEA 132

Query: 238  QYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVF 297
             Y K+DTIAADESF+Q+D G R++K+NTE+R  GP+ R GFYLAFQD GAC++L+SVRVF
Sbjct: 133  PYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVF 192

Query: 298  YKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTP-KLYCGADGDWLVPLGR 356
            +KKCP  V+N A+FP+T+   +S+SLV  RG+C+ +AEE D P KLYC  DG+W+VP+GR
Sbjct: 193  FKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGR 252

Query: 357  CICSTGYE-EIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEK 415
            C C  GYE E   +C AC  G +KA      CS CP +S +  EA+ +C C  GY+RA+ 
Sbjct: 253  CTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADF 312

Query: 416  DPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCED 475
            DPP +ACT  PS PRNV+  +NET++ILEW PP +TGGR D+TY++ICKKC  D   C  
Sbjct: 313  DPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSR 372

Query: 476  CGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQD 535
            C   + F+PR  GL    V +    +H  YTF+I+A+NGVS  S  P    ++ +TT+Q 
Sbjct: 373  CDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQA 432

Query: 536  APSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVI 595
            APS + ++ +  A+  SI LSW  P   NG ILDYEI+YYEKEH +   S  RS+  +  
Sbjct: 433  APSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTAR 492

Query: 596  ITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTL 655
            I GL+P   YV  +R RT  GY  +S K  F+T  +    +  + Q+ +IA +A  G   
Sbjct: 493  IDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVF 552

Query: 656  LVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHE 715
            +V L    ++  R + Y K  + S++ +      G    PG+K YIDP TYEDP+ AV E
Sbjct: 553  VVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGS---PGMKIYIDPFTYEDPNEAVRE 609

Query: 716  FAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREA 775
            FAKEID S ++IE VIGAGEFGEV  GRLK PGKREI VAIKTLK G+ ++QRRDFL EA
Sbjct: 610  FAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEA 669

Query: 776  SIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRI 835
            SIMGQFDHPNIIRLEGVVTK                                        
Sbjct: 670  SIMGQFDHPNIIRLEGVVTK---------------------------------------- 689

Query: 836  PAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAA 895
               RPVMI+ E+MENG+LDSFLR++DG FTVIQLVGMLRGIA+GMKYL++M YVHRDLAA
Sbjct: 690  --SRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAA 747

Query: 896  RNILVNSNLVCKVSDFGLSRVLEDD-PEAAYTTT-GGKIPIRWTAPEAIAYRKFSSASDA 953
            RNILVNSNLVCKVSDFGLSR L+DD  +  YT++ GGKIP+RWTAPEAIAYRKF+SASD 
Sbjct: 748  RNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDV 807

Query: 954  WSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNH 1013
            WSYGIVMWEVMS+GERPYW+MSNQDVI +IE+ YRLP PM CPA+LHQLML CWQK+RN 
Sbjct: 808  WSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNS 867

Query: 1014 RPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESP---GEVPEYPLFVTVGDWLDSIKMG 1070
            RP+F +IV+ LDK+IRNP++L T V  I  +P  P     +P++  F TV DWL +IKM 
Sbjct: 868  RPRFAEIVNTLDKMIRNPASLKT-VATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMV 926

Query: 1071 QYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHM 1120
            QY+++F+ AGFT+  L+++M+ +D+ RIG+ L GHQ++I++SI ++R+ +
Sbjct: 927  QYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQI 976


>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score = 1035 bits (2677), Expect = 0.0
 Identities = 541/1024 (52%), Positives = 682/1024 (66%), Gaps = 73/1024 (7%)

Query: 111  LPLLTAWPGDCSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVC 170
            LPLL   P  C  +      L+DT  V  EL W ++P +GW+ ++  DE   PI TYQVC
Sbjct: 26   LPLLLL-PAGCRALEET---LMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVC 81

Query: 171  NVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESH 230
            NV E +QNNWLRT +I R   Q++YVE+KFT+RDCNSIP + G+CKETFNLFY E+D   
Sbjct: 82   NVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDV 141

Query: 231  GIKFKP----NQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIG 286
                 P    N Y K+DTIA DESF+++D G    ++NT++R  GP+ + GFYLAFQD G
Sbjct: 142  ASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQG 197

Query: 287  ACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTP-KLYCG 345
            AC++L+SVR FYKKC  T    A+FP+T+   + +SLV   G+C+ +A E   P KLYC 
Sbjct: 198  ACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCN 257

Query: 346  ADGDWLVPLGRCICSTGYEEI--EGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSV 403
             DG+W+VP+G C C+TG+E    E  C  C PG YKA  G   C  CPP+S T   A S+
Sbjct: 258  GDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASI 317

Query: 404  CQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVIC 463
            C C   ++RA+ D    ACT  PS PR V+ N+NET+LILEWS P D GGR DL Y+VIC
Sbjct: 318  CTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVIC 377

Query: 464  KKC--GLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFS 521
            KKC      S C  C   + F+PR  GL    V +   ++H  YTFE++A+NGVS  S  
Sbjct: 378  KKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPL 437

Query: 522  PKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQ 581
            P  + A+ +TT+Q APS +  +R   +S +S+ LSW  P   NG ILDYE+KY+EK    
Sbjct: 438  PPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEG- 496

Query: 582  LTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAE-QG 640
               S+  S+  SV + GL+P  +YV  +R RT  GY  YS+  EFET  E    A + Q 
Sbjct: 497  -IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQE 555

Query: 641  QILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTY 700
            Q+ +I  +A  G   +V + +  ++  R Q +  +  +  EK + ++       PG+K Y
Sbjct: 556  QLPLIVGSATAGLVFVVAVVVIAIVCLRKQRH-GSDSEYTEKLQQYIA------PGMKVY 608

Query: 701  IDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLK 760
            IDP TYEDP+ AV EFAKEID S ++IE VIGAGEFGEVC GRLK PG+RE+ VAIKTLK
Sbjct: 609  IDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLK 668

Query: 761  GGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQ 820
             G+ +RQRRDFL EASIMGQFDHPNIIRLEGVVTK                         
Sbjct: 669  VGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTK------------------------- 703

Query: 821  APHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGM 880
                              RPVMI+ E+MEN +LDSFLR +DG FTVIQLVGMLRGIA+GM
Sbjct: 704  -----------------SRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746

Query: 881  KYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EAAYTTT-GGKIPIRWTA 938
            KYLS+M YVHRDLAARNILVNSNLVCKVSDFGLSR LEDDP +  YT++ GGKIPIRWTA
Sbjct: 747  KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806

Query: 939  PEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPAS 998
            PEAIAYRKF+SASD WSYGIVMWEVMSYGERPYW+MSNQDVI ++E+ YRLP PM CP +
Sbjct: 807  PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTA 866

Query: 999  LHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTL--VEDILVMPESPGEVPEYPL 1056
            LHQLML CW ++RN RPKF+ IV+ LDKLIRN ++L  +   +  +  P     VP+Y  
Sbjct: 867  LHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTT 926

Query: 1057 FVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTL 1116
            F TVGDWLD+IKMG+YK +FV+AGF +FDL+++M+ +D+ RIGV L GHQ++I+SSIQ +
Sbjct: 927  FTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDM 986

Query: 1117 RLHM 1120
            RL M
Sbjct: 987  RLQM 990


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score =  940 bits (2430), Expect = 0.0
 Identities = 491/999 (49%), Positives = 648/999 (64%), Gaps = 69/999 (6%)

Query: 128  QVVLLDTTTVLGELGWKTYPLN-GWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWI 186
            +VVLLD     GELGW T+P   GWD +  +  ++ PI+ Y VCNVM  +Q+NWLRTNW+
Sbjct: 28   EVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPIYMYSVCNVMSGDQDNWLRTNWV 86

Query: 187  SRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTIA 246
             R  A++I++E+KFT+RDCNS P    +CKETFNL+Y ESD  +G  F+   +TKIDTIA
Sbjct: 87   YRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIA 146

Query: 247  ADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVR 306
             DE     D   R +KLN E R VGP+ RKGFYLAFQDIGAC+AL+SVRV+YKKCP  ++
Sbjct: 147  PDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQ 206

Query: 307  NLAMFPDTIPRVDSSSLVEVRGSCVKSA---EERDTPKLYCGADGDWLVPLGRCICSTGY 363
             LA FP+TI   D+ SL  V G+CV  A      + P+++C  DG+WLVP+G+C+C  GY
Sbjct: 207  GLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGY 266

Query: 364  EEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACT 423
            E++E +C AC PGF+K  A  + C +CP H+L   E  + C+CE+G+FRA +DP SM CT
Sbjct: 267  EKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCT 326

Query: 424  RPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFI 483
            RPPSAP  +        + L W+PP D+GGR+D+ YSV C++C  ++ +C  C   +R+ 
Sbjct: 327  RPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYS 386

Query: 484  PRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVV 543
                GL   SV V D   H+NYTF +EA NGVS L  S + F   +V+ +Q  P     V
Sbjct: 387  EPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RSFRTASVSINQTEPP---KV 442

Query: 544  RKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPAT 603
            R +  S  S+++SW  P      +  YE+  Y K+ +  +Y+  R++  SV +  L P T
Sbjct: 443  RLEGRSTTSLSVSWSIPPPQQSRVWKYEVT-YRKKGDSNSYNVRRTEGFSVTLDDLAPDT 501

Query: 604  KYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFF 663
             Y+  ++  T  G    S+  EF+T           G + VI   AVG   LLV+  + F
Sbjct: 502  TYLVQVQALTQEGQGAGSKVHEFQTLSPEG-----SGNLAVIGGVAVGVVLLLVLAGVGF 556

Query: 664  LITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPS 723
             I  R     +   ++ +   +   +   +   +KTY+DP TYEDP+ AV +F  EI PS
Sbjct: 557  FIHRR-----RKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPS 611

Query: 724  RIRIERVIGAGEFGEVCSGRLKT-PGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFD 782
             +  ++VIGAGEFGEV  G LKT  GK+E+PVAIKTLK G+ ++QR DFL EA IMGQF 
Sbjct: 612  CVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFS 671

Query: 783  HPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVM 842
            H NIIRLEGV++K                                           +P+M
Sbjct: 672  HHNIIRLEGVISKY------------------------------------------KPMM 689

Query: 843  IVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNS 902
            I+ EYMENG+LD FLR+ DG F+V+QLVGMLRGIA+GMKYL++M YVHRDLAARNILVNS
Sbjct: 690  IITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNS 749

Query: 903  NLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWE 962
            NLVCKVSDFGLSRVLEDDPEA YTT+GGKIPIRWTAPEAI+YRKF+SASD WS+GIVMWE
Sbjct: 750  NLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWE 809

Query: 963  VMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVS 1022
            VM+YGERPYWE+SN +V+ +I +G+RLP PM CP++++QLM+ CWQ+ER  RPKF DIVS
Sbjct: 810  VMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVS 869

Query: 1023 FLDKLIRNPSALHTLVE----DILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVA 1078
             LDKLIR P +L TL +      + +P + G   E   F TV +WL+SIKM QY  +F+A
Sbjct: 870  ILDKLIRAPDSLKTLADFDPRVSIRLPSTSGS--EGVPFRTVSEWLESIKMQQYTEHFMA 927

Query: 1079 AGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLR 1117
            AG+T  + + +M+ DDI+RIGV L GHQ+RI  S+  L+
Sbjct: 928  AGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLK 966


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score =  896 bits (2315), Expect = 0.0
 Identities = 484/1009 (47%), Positives = 640/1009 (63%), Gaps = 81/1009 (8%)

Query: 131  LLDTTTVLGELGWKTYP-LNG-WDAITEMDEHNRPIHTYQVCNVME-PNQNNWLRTNWIS 187
            LL+T     +L W T+P ++G W+ ++ +DE    + TY+VC+V   P Q +WLRT W+ 
Sbjct: 20   LLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLRTGWVP 79

Query: 188  RDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKP----NQYTKID 243
            R  A  +Y  ++FT+ +C S+P    +CKETF +FY ESD        P    N Y K+D
Sbjct: 80   RRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENPYIKVD 139

Query: 244  TIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPF 303
            T+AA+    +    +   K+N +   +GP+ + GFYLAFQD GAC+AL+S+ +FYKKC  
Sbjct: 140  TVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKKCAQ 199

Query: 304  TVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERD--TPKLYCGADGDWLV-PLGRCICS 360
               NL  FP+T+PR     +V V GSCV  A      +P LYC  DG W   P+  C C+
Sbjct: 200  LTVNLTRFPETVPR---ELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCSCA 256

Query: 361  TGYEEIEGS--CHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPP 418
             G+E  EG+  C AC  G +K  +G   C  CP +S +    ++VCQC  GYFRA  DP 
Sbjct: 257  PGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTDPR 316

Query: 419  SMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGG 478
               CT PPSAPR+VV  +N ++L LEWS P ++GGR+DLTY++ C++C    S C  CGG
Sbjct: 317  GAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGS-CAPCGG 375

Query: 479  GLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPS 538
             L F P    L+   V+V        YTFE+ A+NGVS L+  P PF  + VTTD++ P 
Sbjct: 376  DLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREVPP 435

Query: 539  LIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQ------LTYSSTRSKAP 592
             +  +R   +S +S++L+W  P   +GA+LDYE+KY+EK  E       L  S  R++  
Sbjct: 436  AVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAE-- 493

Query: 593  SVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGG 652
               + GLK    Y+  +R R+  GY  + Q+   +T  + S+   EQ   L+  TA VG 
Sbjct: 494  ---LRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQ-LALIAGTAVVGV 549

Query: 653  FTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLA 712
              +LV++ +  L        ++ +    E   +     +L   G K YIDP TYEDP+ A
Sbjct: 550  VLVLVVIVVAVLC-------LRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEA 602

Query: 713  VHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFL 772
            V EFAKEID S ++IE VIGAGEFGEVC GRLK PGK+E  VAIKTLKGG+ +RQRR+FL
Sbjct: 603  VREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFL 662

Query: 773  REASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLP 832
             EASIMGQF+HPNIIRLEGVVT                      NS+             
Sbjct: 663  SEASIMGQFEHPNIIRLEGVVT----------------------NSM------------- 687

Query: 833  PRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRD 892
                   PVMI+ E+MENG+LDSFLR +DG FTVIQLVGMLRGIASGM+YL++M YVHRD
Sbjct: 688  -------PVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRD 740

Query: 893  LAARNILVNSNLVCKVSDFGLSRVLEDD-PEAAYTTT-GGKIPIRWTAPEAIAYRKFSSA 950
            LAARNILVNSNLVCKVSDFGLSR LE++  +  YT++ GGKIPIRWTAPEAIA+RKF+SA
Sbjct: 741  LAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSA 800

Query: 951  SDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKE 1010
            SDAWSYGIVMWEVMS+GERPYW+MSNQDVI +IE+ YRLP P  CP SLHQLML CWQK+
Sbjct: 801  SDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKD 860

Query: 1011 RNHRPKFTDIVSFLDKLIRNPSALHTLVEDI--LVMPESPGEVPEYPLFVTVGDWLDSIK 1068
            RN RP+F  +VS LDK+IRNP++L  +  +      P      P Y  F +VG+WL +IK
Sbjct: 861  RNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIK 920

Query: 1069 MGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLR 1117
            MG+Y+ +F AAGF +F+L+S++S +D+ RIGV L GHQ++I++S+Q ++
Sbjct: 921  MGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMK 969


>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
          Length = 1008

 Score =  870 bits (2248), Expect = 0.0
 Identities = 457/1055 (43%), Positives = 645/1055 (61%), Gaps = 80/1055 (7%)

Query: 100  VREFLLQFGFFLPLLTA-W-PGDCSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEM 157
            +R FL +    L LL   W PG        +V+LLD+     ELGW   P NGW+ I+ +
Sbjct: 10   LRLFLCRMQLCLALLLGPWRPGTAE-----EVILLDSKASQAELGWTALPSNGWEEISGV 64

Query: 158  DEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKE 217
            DEH+RPI TYQVCNV+EPNQ+NWL+T WISR   Q+I+VE++FTLRDC+SIP   GTCKE
Sbjct: 65   DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124

Query: 218  TFNLFYMESDESHG---IKFKPNQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIE 274
            TFN++Y+E++   G    +   ++  KIDTIAADESFTQ DLG+R +KLNTE+RE+GP+ 
Sbjct: 125  TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184

Query: 275  RKGFYLAFQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCV--K 332
            R+GF+LAFQD+GAC+ALVSVRV+YK+C  TVR LA FP T      S+LVEV G+CV   
Sbjct: 185  RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244

Query: 333  SAEERDTPKLYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPP 392
              E    P+++CGADG+WLVP+GRC CS G++E    C AC PGFYK       CS CP 
Sbjct: 245  EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPE 304

Query: 393  HSLTYMEATSVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALI--LEWSPPSD 450
            HS     A++ C C+  Y R+  DPPS +CTRPPSAPR++ ++++ + L+  L W PP+D
Sbjct: 305  HSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPAD 364

Query: 451  TGGRKDLTYSVICKKCGLD--TSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFE 508
            +GGR D+TYS++C +CG +     CE CG  + F+PR  GL   +  +L       YT  
Sbjct: 365  SGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVR 424

Query: 509  IEAMNGVS-ELSFSPKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQ--APAFSNG 565
            + A+NGVS   + +   +  +TV+T   AP     +R+D     S++LSW+   PA + G
Sbjct: 425  VAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPG 484

Query: 566  A-ILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKF 624
            A   +YEI+YYEK   + TYS  ++ AP+V +T LKPAT+YVF IR   + G S  +Q F
Sbjct: 485  ANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRA-ASPGPSWEAQSF 543

Query: 625  ----EFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSE 680
                E +T  E +  + +Q   +V+    +    +L  +     I  R   Y K    + 
Sbjct: 544  NPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAH 603

Query: 681  EKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVC 740
            ++   +    H + P  +T++DP +  D   AVH FAKE+D   + +ER +G G FGE+C
Sbjct: 604  DEEELYF---HFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELC 660

Query: 741  SGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 800
             G L+ PG++E+ VA+  L+    D QR  FL EA  +GQFDH +I+RLEGVVT+     
Sbjct: 661  CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTR----- 715

Query: 801  IGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 860
                                                 G  +MIV EYM +G+LD FLR+H
Sbjct: 716  -------------------------------------GSTLMIVTEYMSHGALDGFLRRH 738

Query: 861  DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDD 920
            +G     QL+G+L G+AS MKYLS+MGYVHR LAAR++LV+S+LVCK+S FG  R   D 
Sbjct: 739  EGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPRDR 796

Query: 921  PEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVI 980
             EA YTT  G+ P  W APE + +  FSSASD WS+GI+MWEVM++GERPYW+MS QDVI
Sbjct: 797  SEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVI 856

Query: 981  LSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVED 1040
             ++E+G+RLP P  CP  LH+LML CWQK+   RP+F+ I S L K++++P         
Sbjct: 857  KAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCA--- 913

Query: 1041 ILVMPESPGEVPE-----YPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDI 1095
            +   P  P  + +     +P F +VG WL+++ + +YK++F AAG+ + + ++ M+  D+
Sbjct: 914  LTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDL 973

Query: 1096 RRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV 1130
              +G+ L  H+  ++S I  L+  ++ +Q +G  V
Sbjct: 974  VSLGISLAEHREALLSGISALQARVLQLQGQGVQV 1008


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score =  743 bits (1919), Expect = 0.0
 Identities = 423/1009 (41%), Positives = 596/1009 (59%), Gaps = 85/1009 (8%)

Query: 128  QVVLLDTTTVLGELGWKTYP-LNGWDAITEMDEHNRPIHTYQVCNVM-EPNQNNWLRTNW 185
            +V L+DT+   GELGW   P  +GW    ++  +  P++ YQ C +    + ++WLR+NW
Sbjct: 27   EVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQDCPMQGRRDTDHWLRSNW 85

Query: 186  ISR-DAAQKIYVEMKFTLRDCNSIPWVLGT--CKETFNLFYMESDESHGIKFKPNQYTKI 242
            I R + A +++VE++FT+RDC S P   G   CKETFNL YMESD+  GI+ +   + K+
Sbjct: 86   IYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLFQKV 145

Query: 243  DTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCP 302
             T+AAD+SFT  DL    +KLN E   +G + R+G YLAF + GAC+ALVSVRVFY++CP
Sbjct: 146  TTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCP 205

Query: 303  FTVRNLAMFPDTIPRVDSSSLVEVRGSCV----KSAEERDTPKLYCGADGDWLVPLGRCI 358
             T+  LA FPDT+P    + LVEV G+C+     S      P+++C  DG+WLVP+GRC 
Sbjct: 206  ETLNGLAQFPDTLP--GPAGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCH 263

Query: 359  CSTGYEE--IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKD 416
            C  GYEE     +C AC  G Y+       C  CP  S    E  ++C CE G++RA  +
Sbjct: 264  CEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRAPGE 323

Query: 417  PPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKC---GLDTSQC 473
             P +ACT PPSAPRN+ F+ + T L L W PP+DTGGR+D+ YSV C +C     D   C
Sbjct: 324  GPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPC 383

Query: 474  EDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTD 533
            + CG G+ F P   GL   +V V     + NYTF +EA NGVS L  S    T+++++  
Sbjct: 384  QPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMG 443

Query: 534  QDAPSLIGV-VRKDWASQNSIALSWQ-APAFSNGAILDYEIKYYEKEHEQLTYSSTRSKA 591
              A SL G+ +R        + L+W  +   S GA L YE+    ++ E+  Y       
Sbjct: 444  H-AESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLTYELHVLNQDEER--YQMVLE-- 498

Query: 592  PSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVG 651
            P V++T L+P T Y+  +R+ T  G   +S   EF T    S      G+I+ +    + 
Sbjct: 499  PRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVS-RGLTGGEIVAVIFGLLL 557

Query: 652  GFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSL 711
            G  LL+ + +F     R +   + + + +  R   +      +  +K Y+D   YEDP+ 
Sbjct: 558  GAALLLGILVF-----RSRRAQRQRQQRQRDRATDVDREDKLW--LKPYVDLQAYEDPAQ 610

Query: 712  AVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDF 771
               +F +E+DP+ + ++ VIG GEFGEV  G L+ P +    VAIKTLK      Q  +F
Sbjct: 611  GALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNF 670

Query: 772  LREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSL 831
            LREA+IMGQF HP+I+ LEGVVTKR                                   
Sbjct: 671  LREATIMGQFSHPHILHLEGVVTKR----------------------------------- 695

Query: 832  PPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHR 891
                   +P+MI+ E+MENG+LD+FLR+ +      QLV ML+GIASGM YLS+  YVHR
Sbjct: 696  -------KPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHR 748

Query: 892  DLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSAS 951
            DLAARNILVN NL CKVSDFGL+R+L DD +  Y T GGKIPIRWTAPEAIA+R F++AS
Sbjct: 749  DLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTAS 807

Query: 952  DAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKER 1011
            D WS+GIVMWEV+S+G++PY EMSNQ+V+ SIE+GYRLP P+ CPA L++LM +CW  +R
Sbjct: 808  DVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDR 867

Query: 1012 NHRPKFTDIVSFLDKLIRNPSALHTLV----EDILVMPESPGE--VPEYPLFVTVGDWLD 1065
              RP F  + + L++L+ NP +L T+        L +P   G   +P    + TV +WL+
Sbjct: 868  ARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIP----YRTVSEWLE 923

Query: 1066 SIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQ 1114
            SI+M +Y  +F +AG  T + +  ++ +D+ ++G+ L GHQ+RI+ SIQ
Sbjct: 924  SIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQ 972


>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
          Length = 1021

 Score =  729 bits (1881), Expect = 0.0
 Identities = 405/1054 (38%), Positives = 581/1054 (55%), Gaps = 138/1054 (13%)

Query: 130  VLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEP----NQNNWLRTNW 185
            VLLDTT    E+GW TYP  GWD ++ +D+  R   T++ C+V        Q+NWL+T++
Sbjct: 35   VLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHF 94

Query: 186  ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHG----IKFKPNQYTK 241
            + R  AQ+ ++ + F++R C+S+    GTC+ETF L+Y +++E         +   ++TK
Sbjct: 95   VERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTK 154

Query: 242  IDTIAADESFTQMD-----------------LGDRI-LKLNTEIREVGPIERKGFYLAFQ 283
            +DTIAADESF                      G R  L+LN + R  GP+ ++GFY+AFQ
Sbjct: 155  VDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQ 214

Query: 284  DIGACIALVSVRVFYKKCPFTVRNLAMFPDT-IPRVDSSSLVEVRGSCVKSAEERDT--- 339
            D GAC+ALV+VR+F   CP  +R+ A FP+T       +SLV   G+CV  AE  +    
Sbjct: 215  DTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVG 274

Query: 340  -------PKLYCGADGDWLVPLGRCICSTGYEEIEG--SCHACRPGFYKAFAGNTKCSKC 390
                   P+L+C  +G W+V +G C C  GY+   G  +C AC  G YK+ AGN  CS C
Sbjct: 275  GQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPC 334

Query: 391  PPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSD 450
            P  S     A  VC C +G++RA  DPP   CT PPSAP+ + F +  +AL+L W  P +
Sbjct: 335  PARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRE 394

Query: 451  TGGRKDLTYSVICKKC-------GLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHV 503
             GGR DL ++V+CK+C             C  C   + F PR  GL  + V+V    +HV
Sbjct: 395  LGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHV 454

Query: 504  NYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFS 563
             Y  E++A+NGVSELS  P    AI V+T  + PS + VV +   + NSI +SW  P  +
Sbjct: 455  PYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQT 514

Query: 564  NGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQK 623
            NG ILDY+++YY++  ++    +  S+  +  +T L P   Y F +R RTA G+  Y  K
Sbjct: 515  NGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGK 574

Query: 624  FEFET--GDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEE 681
              F+T    E S    E+  +++ +      F LL  +T+  ++  R             
Sbjct: 575  VYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQR------------- 621

Query: 682  KRRN-----HLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEF 736
            KRR       LQ       G+K YIDP TYEDP  A+ E A+E+DP+ I+IE VIG G F
Sbjct: 622  KRRGTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSF 681

Query: 737  GEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKR 796
            GEV  GRL+  G+RE  VAI+ L  G  +  +  FL  A+++GQF HPNI+RLEGVVTK 
Sbjct: 682  GEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTK- 740

Query: 797  SFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSF 856
                                                      RP+M++ E+ME G LDSF
Sbjct: 741  -----------------------------------------SRPLMVLTEFMELGPLDSF 759

Query: 857  LRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRV 916
            LR+ +G F+ +QLV M RG+A+ M+YLS   +VHR L+A ++LVNS+LVCKV+  G    
Sbjct: 760  LRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG---- 815

Query: 917  LEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSN 976
                    ++  G    +RW APE IA+ K +++SD WS+GI+MWEVMSYGERPYW+MS 
Sbjct: 816  --------HSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSE 867

Query: 977  QDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHT 1036
            Q+V+ +IE+ +RLP P GCP  LH LML  WQK+R  RP F  +V+  DK+IR P     
Sbjct: 868  QEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKP----- 922

Query: 1037 LVEDILVMPESPGEVP----------EYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDL 1086
               D L     PGE P          ++P   +   WL +I +  Y++NF   G  TF  
Sbjct: 923  ---DTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSD 979

Query: 1087 ISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHM 1120
            ++++S++D+  +G+ L GHQ++++  IQ L+ H+
Sbjct: 980  VAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHL 1013


>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
           sapiens]
          Length = 539

 Score =  728 bits (1879), Expect = 0.0
 Identities = 330/506 (65%), Positives = 414/506 (81%), Gaps = 1/506 (0%)

Query: 126 NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185
           +N+V LLD+ T+ GELGW +YP +GW+ I+ +DEH  PI TYQVCNVM+ +QNNWLRTNW
Sbjct: 27  SNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNW 86

Query: 186 ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245
           + R++AQKIYVE+KFTLRDCNSIP VLGTCKETFNL+YMESD+ HG+KF+ +Q+TKIDTI
Sbjct: 87  VPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTI 146

Query: 246 AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305
           AADESFTQMDLGDRILKLNTEIREVGP+ +KGFYLAFQD+GAC+ALVSVRV++KKCPFTV
Sbjct: 147 AADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTV 206

Query: 306 RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365
           +NLAMFPDT+P +DS SLVEVRGSCV +++E D P++YC  +G+WLVP+G+C C+ GYEE
Sbjct: 207 KNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEE 265

Query: 366 IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
               C ACRPGFYKA  GN KC+KCPPHS T  + +  C+CE  YFRA+KDPPSMACTRP
Sbjct: 266 RGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRP 325

Query: 426 PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
           PS+PRNV+ NINET++IL+WS P DTGGRKD+T+++ICKKCG +  QCE C   +RF+PR
Sbjct: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385

Query: 486 HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
             GL N +V V D ++H NYTFEI+A+NGVSELS  P+ F A+++TT+Q APS +  ++K
Sbjct: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKK 445

Query: 546 DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
           D  S+NSI+LSWQ P   NG ILDYE+KYYEK+ ++ +Y+  R++  +V I+ LKP T Y
Sbjct: 446 DRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIY 505

Query: 606 VFHIRVRTATGYSGYSQKFEFETGDE 631
           VF IR RTA GY   S+KFEFET  +
Sbjct: 506 VFQIRARTAAGYGTNSRKFEFETSPD 531


>gi|27734955 EPH receptor A6 isoform b [Homo sapiens]
          Length = 334

 Score =  596 bits (1536), Expect = e-170
 Identities = 298/308 (96%), Positives = 302/308 (98%), Gaps = 2/308 (0%)

Query: 621 SQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSE 680
           ++K++F      SDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSE
Sbjct: 15  NEKWDFIAS--ASDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSE 72

Query: 681 EKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVC 740
           EKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVC
Sbjct: 73  EKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVC 132

Query: 741 SGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 800
           SGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA
Sbjct: 133 SGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 192

Query: 801 IGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 860
           IGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH
Sbjct: 193 IGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 252

Query: 861 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDD 920
           DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDD
Sbjct: 253 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDD 312

Query: 921 PEAAYTTT 928
           PEAAYTTT
Sbjct: 313 PEAAYTTT 320


>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
           sapiens]
          Length = 495

 Score =  548 bits (1411), Expect = e-155
 Identities = 240/414 (57%), Positives = 318/414 (76%)

Query: 121 CSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNW 180
           C   +  +V LLDT+T+ G+ GW TYP +GWD+I E+DE  +PIHTYQVCNVM PNQNNW
Sbjct: 24  CVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNW 83

Query: 181 LRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYT 240
           LRT+W+ RD A+++Y E+KFTLRDCNS+P VLGTCKETFNL+Y+ESD   G   + +Q+ 
Sbjct: 84  LRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFL 143

Query: 241 KIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKK 300
           KIDTIAADESFT  DLG R LKLNTE+R VGP+ ++GFYLAFQDIGAC+A++S+R++YKK
Sbjct: 144 KIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKK 203

Query: 301 CPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICS 360
           CP  VRNLA F + +   DSSSLVEVRG CV+ +EERDTPK+YC A+G+WLVP+G+C+CS
Sbjct: 204 CPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCS 263

Query: 361 TGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSM 420
            GYEE   +C AC  GFYK+  G+  C++CPPHS +   A   C C+  Y+RA  DPPS 
Sbjct: 264 AGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSS 323

Query: 421 ACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGL 480
           ACTRPPSAP N++ ++N T++ LEW+PP D GGR D+TY+ +C++C    S+CE CG G 
Sbjct: 324 ACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGT 383

Query: 481 RFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQ 534
           RF+P+ T L+  S++V + ++H+NY+F IEA+NGVS+LS  P+    + +TT+Q
Sbjct: 384 RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQ 437


>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
          Length = 295

 Score =  308 bits (790), Expect = 1e-83
 Identities = 153/278 (55%), Positives = 198/278 (71%), Gaps = 12/278 (4%)

Query: 100 VREFLLQFGFFLPLLTA-W-PGDCSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEM 157
           +R FL +    L LL   W PG        +V+LLD+     ELGW   P NGW+ I+ +
Sbjct: 10  LRLFLCRMQLCLALLLGPWRPGTAE-----EVILLDSKASQAELGWTALPSNGWEEISGV 64

Query: 158 DEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKE 217
           DEH+RPI TYQVCNV+EPNQ+NWL+T WISR   Q+I+VE++FTLRDC+SIP   GTCKE
Sbjct: 65  DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124

Query: 218 TFNLFYMESDESHG---IKFKPNQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIE 274
           TFN++Y+E++   G    +   ++  KIDTIAADESFTQ DLG+R +KLNTE+RE+GP+ 
Sbjct: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184

Query: 275 RKGFYLAFQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCV--K 332
           R+GF+LAFQD+GAC+ALVSVRV+YK+C  TVR LA FP T      S+LVEV G+CV   
Sbjct: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244

Query: 333 SAEERDTPKLYCGADGDWLVPLGRCICSTGYEEIEGSC 370
             E    P+++CGADG+WLVP+GRC CS G++E    C
Sbjct: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFC 282


>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
          Length = 1074

 Score =  216 bits (549), Expect = 1e-55
 Identities = 121/332 (36%), Positives = 175/332 (52%), Gaps = 49/332 (14%)

Query: 702  DPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKG 761
            + DTY  PS   +E  +E    RI + R IG G+FG+V  G   +P    + VAIKT K 
Sbjct: 425  EEDTYTMPSTRDYEIQRE----RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKN 480

Query: 762  GHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQA 821
               D  R  FL+EA  M QFDHP+I++L GV+T+                          
Sbjct: 481  CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN------------------------- 515

Query: 822  PHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMK 881
                              PV I++E    G L SFL+       +  L+     +++ + 
Sbjct: 516  ------------------PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA 557

Query: 882  YLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEA 941
            YL    +VHRD+AARN+LV+SN   K+ DFGLSR +ED     Y  + GK+PI+W APE+
Sbjct: 558  YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPES 615

Query: 942  IAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQ 1001
            I +R+F+SASD W +G+ MWE++ +G +P+  + N DVI  IE G RLP P  CP +L+ 
Sbjct: 616  INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 675

Query: 1002 LMLHCWQKERNHRPKFTDIVSFLDKLIRNPSA 1033
            LM  CW  + + RP+FT++ + L  ++    A
Sbjct: 676  LMTKCWAYDPSRRPRFTELKAQLSTILEEEKA 707


>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
          Length = 1052

 Score =  216 bits (549), Expect = 1e-55
 Identities = 121/332 (36%), Positives = 175/332 (52%), Gaps = 49/332 (14%)

Query: 702  DPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKG 761
            + DTY  PS   +E  +E    RI + R IG G+FG+V  G   +P    + VAIKT K 
Sbjct: 403  EEDTYTMPSTRDYEIQRE----RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKN 458

Query: 762  GHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQA 821
               D  R  FL+EA  M QFDHP+I++L GV+T+                          
Sbjct: 459  CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN------------------------- 493

Query: 822  PHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMK 881
                              PV I++E    G L SFL+       +  L+     +++ + 
Sbjct: 494  ------------------PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA 535

Query: 882  YLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEA 941
            YL    +VHRD+AARN+LV+SN   K+ DFGLSR +ED     Y  + GK+PI+W APE+
Sbjct: 536  YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPES 593

Query: 942  IAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQ 1001
            I +R+F+SASD W +G+ MWE++ +G +P+  + N DVI  IE G RLP P  CP +L+ 
Sbjct: 594  INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 653

Query: 1002 LMLHCWQKERNHRPKFTDIVSFLDKLIRNPSA 1033
            LM  CW  + + RP+FT++ + L  ++    A
Sbjct: 654  LMTKCWAYDPSRRPRFTELKAQLSTILEEEKA 685


>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
          Length = 543

 Score =  210 bits (534), Expect = 7e-54
 Identities = 126/310 (40%), Positives = 168/310 (54%), Gaps = 52/310 (16%)

Query: 717  AKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREAS 776
            A EI    +R+E  +G G FGEV  G      K    VAIKTLK G M  +   FL+EA 
Sbjct: 269  AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTMMPEA--FLQEAQ 322

Query: 777  IMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIP 836
            IM +  H  ++ L  VV++                                         
Sbjct: 323  IMKKLRHDKLVPLYAVVSEE---------------------------------------- 342

Query: 837  AGRPVMIVVEYMENGSLDSFLRKHDGHFTVI-QLVGMLRGIASGMKYLSDMGYVHRDLAA 895
               P+ IV E+M  GSL  FL++ DG +  + QLV M   IA GM Y+  M Y+HRDL A
Sbjct: 343  ---PIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRA 399

Query: 896  RNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWS 955
             NILV  NLVCK++DFGL+R++ED+   A    G K PI+WTAPEA  Y +F+  SD WS
Sbjct: 400  ANILVGENLVCKIADFGLARLIEDNEYTA--RQGAKFPIKWTAPEAALYGRFTIKSDVWS 457

Query: 956  YGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRP 1015
            +GI+  E+++ G  PY  M N++V+  +E GYR+P P GCP SLH+LM  CW+K+ + RP
Sbjct: 458  FGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERP 517

Query: 1016 KFTDIVSFLD 1025
             F  I SFL+
Sbjct: 518  TFEYIQSFLE 527


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score =  207 bits (527), Expect = 5e-53
 Identities = 117/308 (37%), Positives = 168/308 (54%), Gaps = 52/308 (16%)

Query: 719  EIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIM 778
            EI    +++ + +G G+FGEV  G      K    VAIKTLK G M  +   FL EA IM
Sbjct: 265  EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318

Query: 779  GQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAG 838
             +  H  +++L  VV++                                           
Sbjct: 319  KKLKHDKLVQLYAVVSEE------------------------------------------ 336

Query: 839  RPVMIVVEYMENGSLDSFLRKHDGHFTVI-QLVGMLRGIASGMKYLSDMGYVHRDLAARN 897
             P+ IV EYM  GSL  FL+  +G    +  LV M   +A+GM Y+  M Y+HRDL + N
Sbjct: 337  -PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSAN 395

Query: 898  ILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYG 957
            ILV + L+CK++DFGL+R++ED+   A    G K PI+WTAPEA  Y +F+  SD WS+G
Sbjct: 396  ILVGNGLICKIADFGLARLIEDNEYTA--RQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 453

Query: 958  IVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKF 1017
            I++ E+++ G  PY  M+N++V+  +E GYR+P P  CP SLH+LM+HCW+K+   RP F
Sbjct: 454  ILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513

Query: 1018 TDIVSFLD 1025
              + SFL+
Sbjct: 514  EYLQSFLE 521


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sapiens]
          Length = 536

 Score =  206 bits (525), Expect = 8e-53
 Identities = 125/310 (40%), Positives = 165/310 (53%), Gaps = 52/310 (16%)

Query: 717  AKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREAS 776
            A EI    +R+E  +G G FGEV  G      +    VAIKTLK G M  +   FL+EA 
Sbjct: 262  AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTMSPEA--FLQEAQ 315

Query: 777  IMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIP 836
            +M +  H  +++L  VV++                                         
Sbjct: 316  VMKKLRHEKLVQLYAVVSEE---------------------------------------- 335

Query: 837  AGRPVMIVVEYMENGSLDSFLRKHDGHFTVI-QLVGMLRGIASGMKYLSDMGYVHRDLAA 895
               P+ IV EYM  GSL  FL+   G +  + QLV M   IASGM Y+  M YVHRDL A
Sbjct: 336  ---PIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRA 392

Query: 896  RNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWS 955
             NILV  NLVCKV+DFGL+R++ED+   A    G K PI+WTAPEA  Y +F+  SD WS
Sbjct: 393  ANILVGENLVCKVADFGLARLIEDNEYTA--RQGAKFPIKWTAPEAALYGRFTIKSDVWS 450

Query: 956  YGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRP 1015
            +GI++ E+ + G  PY  M N++V+  +E GYR+P P  CP SLH LM  CW+KE   RP
Sbjct: 451  FGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERP 510

Query: 1016 KFTDIVSFLD 1025
             F  + +FL+
Sbjct: 511  TFEYLQAFLE 520


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapiens]
          Length = 536

 Score =  206 bits (525), Expect = 8e-53
 Identities = 125/310 (40%), Positives = 165/310 (53%), Gaps = 52/310 (16%)

Query: 717  AKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREAS 776
            A EI    +R+E  +G G FGEV  G      +    VAIKTLK G M  +   FL+EA 
Sbjct: 262  AWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTMSPEA--FLQEAQ 315

Query: 777  IMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIP 836
            +M +  H  +++L  VV++                                         
Sbjct: 316  VMKKLRHEKLVQLYAVVSEE---------------------------------------- 335

Query: 837  AGRPVMIVVEYMENGSLDSFLRKHDGHFTVI-QLVGMLRGIASGMKYLSDMGYVHRDLAA 895
               P+ IV EYM  GSL  FL+   G +  + QLV M   IASGM Y+  M YVHRDL A
Sbjct: 336  ---PIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRA 392

Query: 896  RNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWS 955
             NILV  NLVCKV+DFGL+R++ED+   A    G K PI+WTAPEA  Y +F+  SD WS
Sbjct: 393  ANILVGENLVCKVADFGLARLIEDNEYTA--RQGAKFPIKWTAPEAALYGRFTIKSDVWS 450

Query: 956  YGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRP 1015
            +GI++ E+ + G  PY  M N++V+  +E GYR+P P  CP SLH LM  CW+KE   RP
Sbjct: 451  FGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERP 510

Query: 1016 KFTDIVSFLD 1025
             F  + +FL+
Sbjct: 511  TFEYLQAFLE 520


>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
          Length = 534

 Score =  204 bits (518), Expect = 5e-52
 Identities = 117/310 (37%), Positives = 167/310 (53%), Gaps = 52/310 (16%)

Query: 717  AKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREAS 776
            A E+    + +E+ +G G F EV  G      K    VAIKTLK G M  +   FL EA 
Sbjct: 260  AWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQ 313

Query: 777  IMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIP 836
            IM +  H  +++L  VV++                                         
Sbjct: 314  IMKKLKHDKLVQLYAVVSEE---------------------------------------- 333

Query: 837  AGRPVMIVVEYMENGSLDSFLRKHDGHFTVI-QLVGMLRGIASGMKYLSDMGYVHRDLAA 895
               P+ IV EYM  GSL  FL+  +G    +  LV M   +A+GM Y+  M Y+HRDL +
Sbjct: 334  ---PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRS 390

Query: 896  RNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWS 955
             NILV + L+CK++DFGL+R++ED+   A    G K PI+WTAPEA  Y +F+  SD WS
Sbjct: 391  ANILVGNGLICKIADFGLARLIEDNEYTA--RQGAKFPIKWTAPEAALYGRFTIKSDVWS 448

Query: 956  YGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRP 1015
            +GI++ E+++ G  PY  M+N++V+  +E GYR+P P  CP SLH+LM+HCW+K+   RP
Sbjct: 449  FGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERP 508

Query: 1016 KFTDIVSFLD 1025
             F  + SFL+
Sbjct: 509  TFEYLQSFLE 518


>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
          Length = 526

 Score =  203 bits (516), Expect = 9e-52
 Identities = 115/310 (37%), Positives = 165/310 (53%), Gaps = 52/310 (16%)

Query: 717  AKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREAS 776
            A EI    +++E+ +GAG+FGEV         K    VA+KT+K G M  +   FL EA+
Sbjct: 254  AWEIPRESLKLEKKLGAGQFGEVWMATYNKHTK----VAVKTMKPGSMSVEA--FLAEAN 307

Query: 777  IMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIP 836
            +M    H  +++L  VVTK                                         
Sbjct: 308  VMKTLQHDKLVKLHAVVTKE---------------------------------------- 327

Query: 837  AGRPVMIVVEYMENGSLDSFLRKHDGHFTVI-QLVGMLRGIASGMKYLSDMGYVHRDLAA 895
               P+ I+ E+M  GSL  FL+  +G    + +L+     IA GM ++    Y+HRDL A
Sbjct: 328  ---PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRA 384

Query: 896  RNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWS 955
             NILV+++LVCK++DFGL+RV+ED+   A    G K PI+WTAPEAI +  F+  SD WS
Sbjct: 385  ANILVSASLVCKIADFGLARVIEDNEYTA--REGAKFPIKWTAPEAINFGSFTIKSDVWS 442

Query: 956  YGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRP 1015
            +GI++ E+++YG  PY  MSN +VI ++E GYR+P P  CP  L+ +M+ CW+     RP
Sbjct: 443  FGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERP 502

Query: 1016 KFTDIVSFLD 1025
             F  I S LD
Sbjct: 503  TFEYIQSVLD 512


>gi|4503787 fyn-related kinase [Homo sapiens]
          Length = 505

 Score =  201 bits (510), Expect = 4e-51
 Identities = 118/303 (38%), Positives = 158/303 (52%), Gaps = 54/303 (17%)

Query: 719  EIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIM 778
            EID + I++ + +G+G+FGEV  G          PVA+KTLK G MD    DFLREA IM
Sbjct: 228  EIDRNSIQLLKRLGSGQFGEVWEGLWNNT----TPVAVKTLKPGSMDPN--DFLREAQIM 281

Query: 779  GQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAG 838
                HP +I+L  V T                                            
Sbjct: 282  KNLRHPKLIQLYAVCTLED----------------------------------------- 300

Query: 839  RPVMIVVEYMENGSLDSFLRKHDG---HFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAA 895
             P+ I+ E M +GSL  +L+   G   H T  Q V M   +ASGM YL    Y+HRDLAA
Sbjct: 301  -PIYIITELMRHGSLQEYLQNDTGSKIHLT--QQVDMAAQVASGMAYLESRNYIHRDLAA 357

Query: 896  RNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGG-KIPIRWTAPEAIAYRKFSSASDAW 954
            RN+LV  + + KV+DFGL+RV + D E  Y +    K+P++WTAPEAI   KFS  SD W
Sbjct: 358  RNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVW 417

Query: 955  SYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHR 1014
            S+GI+++E+++YG+ PY  M+   VI  + + YRLP P  CP   + +ML CW  E   R
Sbjct: 418  SFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKER 477

Query: 1015 PKF 1017
            P F
Sbjct: 478  PTF 480


>gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]
          Length = 482

 Score =  197 bits (502), Expect = 4e-50
 Identities = 107/273 (39%), Positives = 152/273 (55%), Gaps = 48/273 (17%)

Query: 754  VAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRA 813
            VAIKTLK G M  +   FL EA IM +  H  +++L  VV++                  
Sbjct: 241  VAIKTLKPGTMSPE--SFLEEAQIMKKLKHDKLVQLYAVVSEE----------------- 281

Query: 814  GFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVI-QLVGM 872
                                      P+ IV EYM  GSL  FL+  +G    +  LV M
Sbjct: 282  --------------------------PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDM 315

Query: 873  LRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKI 932
               +A+GM Y+  M Y+HRDL + NILV + L+CK++DFGL+R++ED+   A    G K 
Sbjct: 316  AAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTA--RQGAKF 373

Query: 933  PIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAP 992
            PI+WTAPEA  Y +F+  SD WS+GI++ E+++ G  PY  M+N++V+  +E GYR+P P
Sbjct: 374  PIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 433

Query: 993  MGCPASLHQLMLHCWQKERNHRPKFTDIVSFLD 1025
              CP SLH+LM+HCW+K+   RP F  + SFL+
Sbjct: 434  QDCPISLHELMIHCWKKDPEERPTFEYLQSFLE 466


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,252,624
Number of Sequences: 37866
Number of extensions: 2493683
Number of successful extensions: 23813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 646
Number of HSP's successfully gapped in prelim test: 553
Number of HSP's that attempted gapping in prelim test: 17570
Number of HSP's gapped (non-prelim): 5386
length of query: 1130
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1017
effective length of database: 13,968,660
effective search space: 14206127220
effective search space used: 14206127220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.