Guide to the Human Genome
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Search of human proteins with 142976757

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|142976757 immediate early response 5 [Homo sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|142976757 immediate early response 5 [Homo sapiens]                687   0.0  
gi|148727370 immediate early response 5-like [Homo sapiens]            91   1e-18
gi|48675811 immediate early response 2 [Homo sapiens]                  83   3e-16
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    58   1e-08
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      57   2e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    57   2e-08
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             55   1e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   1e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  54   2e-07
gi|122937321 UNC homeobox [Homo sapiens]                               52   9e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    51   1e-06
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              51   2e-06
gi|153792074 proline rich 12 [Homo sapiens]                            49   6e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    49   8e-06
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    48   1e-05
gi|30795231 brain abundant, membrane attached signal protein 1 [...    48   1e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   1e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   1e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    48   1e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    48   1e-05
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    48   1e-05
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       48   1e-05
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       48   1e-05
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       47   2e-05
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       47   2e-05
gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo sap...    47   3e-05
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       47   3e-05
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       47   3e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     47   3e-05
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 46   4e-05

>gi|142976757 immediate early response 5 [Homo sapiens]
          Length = 327

 Score =  687 bits (1772), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGP 60
           MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGP
Sbjct: 1   MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGP 60

Query: 61  AGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVA 120
           AGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVA
Sbjct: 61  AGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVA 120

Query: 121 TVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPL 180
           TVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPL
Sbjct: 121 TVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPL 180

Query: 181 GGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLK 240
           GGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLK
Sbjct: 181 GGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLK 240

Query: 241 KPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPE 300
           KPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPE
Sbjct: 241 KPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPE 300

Query: 301 AAEPGQICCDKPVLRDMNPWSTAIVAF 327
           AAEPGQICCDKPVLRDMNPWSTAIVAF
Sbjct: 301 AAEPGQICCDKPVLRDMNPWSTAIVAF 327


>gi|148727370 immediate early response 5-like [Homo sapiens]
          Length = 404

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 90/275 (32%), Positives = 111/275 (40%), Gaps = 79/275 (28%)

Query: 1   MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGP 60
           ME  L+A  ++SISL KI++SR QRGGIKLHKNLLVS VLR+ARQ+YLS+    LY    
Sbjct: 1   MECALDAQSLISISLRKIHSSRTQRGGIKLHKNLLVSYVLRNARQLYLSERYAELYRRQQ 60

Query: 61  AGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVA 120
                 PP  Q    A      +  P  PA+ A +                         
Sbjct: 61  QQQQQQPPHHQHQHLA------YAAPGMPASAADF------------------------- 89

Query: 121 TVTGVGDVFQGGEADATEAA---------------------WSRVEGPRQAAAREAEGT- 158
              G   +  GG+A+A E A                       +   PR  AA  A G  
Sbjct: 90  ---GPLQLGGGGDAEAREPAARHQLHQLHQLHQLHLQQQLHQHQHPAPRGCAAAAAAGAP 146

Query: 159 AGGWGVFPEV--SRAARRPCGCPLGGED-PPGTPAATPRAACCCAPQPAEDEPPAPPAVC 215
           AGG G   E+    A + P G P  G+   P  P          AP P    PPAP A+C
Sbjct: 147 AGGAGALSELPGCAALQPPHGAPHRGQPLEPLQPGP--------APLPLPLPPPAPAALC 198

Query: 216 PR-----KRCAAGVGGGPAGC-------PAPGSTP 238
           PR       C+A  G  P          PAP S+P
Sbjct: 199 PRDPRAPAACSAPPGAAPPAAAASPPASPAPASSP 233



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 78/277 (28%), Positives = 100/277 (36%), Gaps = 61/277 (22%)

Query: 59  GPAGTPAPPPQQQPG-----EPAAGPPAGWGEPP---PPAARASWPETEPQPERSSVSDA 110
           GPA  P P P   P      +P A  PA    PP   PPAA AS P   P P     S  
Sbjct: 181 GPAPLPLPLPPPAPAALCPRDPRA--PAACSAPPGAAPPAAAAS-PPASPAP----ASSP 233

Query: 111 PRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSR 170
                  P  +  G+    Q    D      + VE                 G   +   
Sbjct: 234 GFYRGAYPTPSDFGLHCSSQTTVLDLDTHVVTTVEN----------------GYLHQDCC 277

Query: 171 AARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAG 230
           A+     CP  G+  PG P     A C     P ++E          +  A G+G  P  
Sbjct: 278 ASAH---CPCCGQGAPG-PGLASAAGCKRKYYPGQEEEEDD------EEDAGGLGAEP-- 325

Query: 231 CPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGRE 290
              PG  P    +R   +        DA      N++NLISIFGS FSGL+ + P     
Sbjct: 326 ---PGGAPFAPCKRARFEDFCPDSSPDAS-----NISNLISIFGSGFSGLVSRQP----- 372

Query: 291 EEEGEESGPEAAEPGQICCDKPVLRDMNPWSTAIVAF 327
            +  E+  P     GQ+C  K  L  +  W+ AIVAF
Sbjct: 373 -DSSEQPPP---LNGQLCA-KQALASLGAWTRAIVAF 404


>gi|48675811 immediate early response 2 [Homo sapiens]
          Length = 223

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 65/213 (30%), Positives = 100/213 (46%), Gaps = 17/213 (7%)

Query: 1   MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGL--YLA 58
           ME + EA RI+++S+ K+Y+SR+QRGG++LH++L +SLV+RSAR++YLS     L   ++
Sbjct: 1   MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVEALEPEVS 60

Query: 59  GPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVP 118
            PA  P+ P    P E  +       +   P       +  P  E +S   APR      
Sbjct: 61  LPAALPSDPRLHPPREAESTAETATPDGEHPFPEPMDTQEAPTAEETSACCAPR---PAK 117

Query: 119 VATVTGVGDVFQGGEADATEAAWSRVE-------GPRQAAAREAEGTAGGWGVFPEVSRA 171
           V+       +  GG+A    +  +R+E          + A R     A   G FP ++R 
Sbjct: 118 VSRKRRSSSLSDGGDAGLVPSKKARLEEKEEEEGASSEVADRLQPPPAQAEGAFPNLARV 177

Query: 172 ARRPCGCPLGGEDPPGTPAATPRAACCCAPQPA 204
            +R     L       +PAA P A   C  +PA
Sbjct: 178 LQRRFSGLLN-----CSPAAPPTAPPACEAKPA 205



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 49/191 (25%), Positives = 73/191 (38%), Gaps = 43/191 (22%)

Query: 143 RVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQ 202
           R+  PR+A +     T  G   FPE           P+  ++ P         + CCAP+
Sbjct: 70  RLHPPREAESTAETATPDGEHPFPE-----------PMDTQEAP----TAEETSACCAPR 114

Query: 203 PAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEME 262
           PA+        V  ++R ++   GG AG       P KK R   ++   G   + A+ ++
Sbjct: 115 PAK--------VSRKRRSSSLSDGGDAGL-----VPSKKARLEEKEEEEGASSEVADRLQ 161

Query: 263 ------TGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAEPGQICCDKPVLRD 316
                  G   NL  +    FSGLL  SP           + P A E    C  +P    
Sbjct: 162 PPPAQAEGAFPNLARVLQRRFSGLLNCSPA-------APPTAPPACEAKPAC--RPADSM 212

Query: 317 MNPWSTAIVAF 327
           +N    A+VAF
Sbjct: 213 LNVLVRAVVAF 223


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 63/212 (29%), Positives = 74/212 (34%), Gaps = 33/212 (15%)

Query: 53  PGLYLAGPAGT-PAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAP 111
           PG   +GP    P PPP QQ  +P   PP    +PPP       P   PQP +      P
Sbjct: 49  PGPGQSGPKPPIPPPPPHQQQQQP---PPQ---QPPPQQPPPHQPPPHPQPHQQQQPPPP 102

Query: 112 RVGDEVPVATVTGVGDVFQG-GEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSR 170
                 PV        V QG G A    +A      P  ++A  A     G    P  S 
Sbjct: 103 PQDSSKPV--------VAQGPGPAPGVGSA-----PPASSSAPPATPPTSG---APPGSG 146

Query: 171 AARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPA- 229
               P   P     PPG P  TP ++      P    PP PPA  P        G GP  
Sbjct: 147 PGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGG 206

Query: 230 -------GCPAPGSTP-LKKPRRNLEQPPSGG 253
                  G P PG  P L  P  + + P  GG
Sbjct: 207 PKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 30/81 (37%), Positives = 35/81 (43%), Gaps = 7/81 (8%)

Query: 51  PCPGLYLAGPAGTPAPP--PQQQPGEPAAGPPAGWGEPPPPAARASWP-ETEPQPERSSV 107
           P PG+  A PA + APP  P      P +GP  G    PPPA  ++ P    P P  S V
Sbjct: 117 PAPGVGSAPPASSSAPPATPPTSGAPPGSGP--GPTPTPPPAVTSAPPGAPPPTPPSSGV 174

Query: 108 SDAP--RVGDEVPVATVTGVG 126
              P    G   P A V G G
Sbjct: 175 PTTPPQAGGPPPPPAAVPGPG 195


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 64/212 (30%), Positives = 73/212 (34%), Gaps = 31/212 (14%)

Query: 59  GPAGTPAPPPQQQPGEPAA-----GPPAGWGEPPPP--AARASWPETEPQP-ERSSVSDA 110
           GPAG P    +  P  PA      G P   GEP PP  A  A  P  + QP  +    DA
Sbjct: 773 GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA 832

Query: 111 PRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSR 170
              GD  P       G     G   A          P    AR + G  G  G FP  + 
Sbjct: 833 GAKGDAGPPGPAGPAGPPGPIGNVGA----------PGAKGARGSAGPPGATG-FPGAAG 881

Query: 171 AARRPCGCPLGGEDPPGTPAAT-------PRAACCCAPQPAEDEPPAPPAVCPRKRCAAG 223
               P   P G   PPG P          PR     A +P E  PP PP   P     + 
Sbjct: 882 RVGPPG--PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG--PAGEKGSP 937

Query: 224 VGGGPAGCP-APGSTPLKKPRRNLEQPPSGGE 254
              GPAG P  PG   +   R  +  P   GE
Sbjct: 938 GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGE 969



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 56/186 (30%), Positives = 61/186 (32%), Gaps = 16/186 (8%)

Query: 57  LAGPAGTP-APPPQQQPGEP----AAGPPAGWGEPPPPA---ARASWPETEPQPERSSVS 108
           L G  G P AP P    G      AAGPP   G   PP    A  +  E  PQ  R S  
Sbjct: 306 LPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEG 365

Query: 109 DAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEV 168
                G+  P       G     G AD    A      P  A A    G  G     P  
Sbjct: 366 PQGVRGEPGPPGPAGAAGPAGNPG-ADGQPGAKGANGAPGIAGAPGFPGARG-----PSG 419

Query: 169 SRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGP 228
            +    P G P G    PG P +         P P   + P  PA    KR A G   GP
Sbjct: 420 PQGPGGPPG-PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARG-EPGP 477

Query: 229 AGCPAP 234
            G P P
Sbjct: 478 TGLPGP 483



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 54/207 (26%), Positives = 65/207 (31%), Gaps = 26/207 (12%)

Query: 57  LAGPAGTPAPP----PQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPR 112
           L GP G P P     P  +PGEP A  P G   PP P  +        +P R      P 
Sbjct: 189 LPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG 248

Query: 113 VGDEVPVATVTGVGDV-----FQGGEADATEAAWSRVEG-PRQAAAREAEGTAGGWGVFP 166
                 +    G+  +     F G +    +A  +  +G P       A G  G  G+  
Sbjct: 249 PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308

Query: 167 EVSR-AARRPCGC--------------PLGGEDPPGTPAATPRAACCCAPQPAEDEPPAP 211
           E  R  A  P G               P G   PPG P A           P   E P  
Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG 368

Query: 212 PAVCPRKRCAAGVGGGPAGCPAPGSTP 238
               P     AG   GPAG P     P
Sbjct: 369 VRGEPGPPGPAG-AAGPAGNPGADGQP 394



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 54/193 (27%), Positives = 65/193 (33%), Gaps = 34/193 (17%)

Query: 59  GPAGTPAPP-PQQQPGEPAA-GPPAGWGEPPPPAARASWPETEPQPERSSVS----DAPR 112
           GP G   PP P  + G+  A G P   G P PP  R   P +   P    V+     A  
Sbjct: 452 GPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGG-PGSRGFPGADGVAGPKGPAGE 510

Query: 113 VGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAA 172
            G   P       G+  + GEA                 A+   G+ G  G  P+     
Sbjct: 511 RGSPGPAGPKGSPGEAGRPGEAGL-------------PGAKGLTGSPGSPG--PDGKTGP 555

Query: 173 RRPCGCPLGGEDPPGTPAATPRAACCCAPQP--AEDEP--------PAPP-AVCPRKRCA 221
             P G   G   PPG P A  +A     P P  A  EP        P PP AV P  +  
Sbjct: 556 PGPAGQD-GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDG 614

Query: 222 AGVGGGPAGCPAP 234
                GP G   P
Sbjct: 615 EAGAQGPPGPAGP 627



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 63/219 (28%), Positives = 74/219 (33%), Gaps = 40/219 (18%)

Query: 59  GPAGTPA----PPPQQQPGEPAA----GPPAGWGEPPPPAARASWPETEPQPERSSVSDA 110
           GPAG+P     P P   PGE       G P   G P P  AR         P    V   
Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE----RGFPGERGVQGP 690

Query: 111 PRVGDEVPVATVTGVGDVFQGGEADATEAAWSR-------VEGPRQAAA----REAEGTA 159
           P  G   P       G+    G+A A  A  S+       + G R AA     +   G A
Sbjct: 691 P--GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA 748

Query: 160 GGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKR 219
           G  G      +   R    P+G   PPG PA         AP    +  P+ PA     R
Sbjct: 749 GPKGADGSPGKDGVRGLTGPIG---PPG-PAG--------APGDKGESGPSGPAGPTGAR 796

Query: 220 CAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDA 258
            A G  G P     PG      P     QP + GE  DA
Sbjct: 797 GAPGDRGEPG---PPGPAGFAGPPGADGQPGAKGEPGDA 832



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 61/229 (26%), Positives = 69/229 (30%), Gaps = 36/229 (15%)

Query: 57   LAGPAGTPAPP-PQQQPGE---PAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPR 112
            L GP+G P    P    GE   P    P G   PP  + R   P  E  P R     A  
Sbjct: 975  LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034

Query: 113  VGDEVPVATVTGV-------GDVFQGGEA-DATEAAWSRVEGP-RQAAAREAEGTAGGWG 163
               E   A   G        G V   G++ D  E   +   GP     AR   G  G  G
Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRG 1094

Query: 164  VFPEVSRAARRPCGCPLGG---EDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRC 220
               E      R      G    + PPG P +        A  PA    P   A  P K  
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDG 1154

Query: 221  AAGVGG--------------GPAGCPAPGSTPLKKPRRNLEQPPSGGED 255
              G+ G              GP G P P   P          PPS G D
Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPP------GPPGPPSAGFD 1197



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 53/203 (26%), Positives = 65/203 (32%), Gaps = 32/203 (15%)

Query: 54  GLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPP-----PPAARASWPETEPQPERSSVS 108
           G+ + GP G   P  +  PG P A  P G+  PP     P A+    P   P P   +  
Sbjct: 174 GISVPGPMGPSGP--RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGD 231

Query: 109 DAP-----RVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAARE-AEGTAGGW 162
           D       R G+  P           QG       A    ++G R  +  + A+G AG  
Sbjct: 232 DGEAGKPGRPGERGPPGP--------QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPA 283

Query: 163 GVFPEVSRAARR-------PCGCP--LGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPA 213
           G   E              P G P   G    PG   A        A  P     PA P 
Sbjct: 284 GPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP 343

Query: 214 VCPRKRCAAGVGG--GPAGCPAP 234
             P    A G  G  GP G   P
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGP 366



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 58   AGPAGTPAPP-PQQQPGEPAAGPPAGWGEPPPPAARA 93
            AGP G P PP P   PG P+AG    +  P PP  +A
Sbjct: 1174 AGPVGPPGPPGPPGPPGPPSAGFDFSF-LPQPPQEKA 1209


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 61/222 (27%), Positives = 78/222 (35%), Gaps = 30/222 (13%)

Query: 49   SDPCPGLYLAGPAGTPAPP-PQQQPGEPAAGPPAGWGEPPPPAAR-ASWPE--TEPQPER 104
            S P        P G PA P P+  P  PAA PP+  G P  P+ + A  P   T P P+ 
Sbjct: 916  SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975

Query: 105  SSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGV 164
               + +P+     P AT        +GG A  +       +G     A       G    
Sbjct: 976  GPATPSPKGAPTPPAATPPSP----KGGPATPSP------KGAPTPPAVTPPSPKGSPAA 1025

Query: 165  FPEVSRAARRPCGCPLGGEDPPGTPAATPR--------AACCCAPQPAEDEP-----PAP 211
             P    A+  P   P     P G+PAATP         AA   +P+     P     P P
Sbjct: 1026 TPFPKGASTPPAATP---PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082

Query: 212  PAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGG 253
            PA  P           P G P P +     P+  L  PP  G
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 59/213 (27%), Positives = 75/213 (35%), Gaps = 37/213 (17%)

Query: 62   GTPAPPPQQQPGEPAAGPPA---GWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVP 118
            G   PPP+  P  PAA PP+   G   PPP  A  +   T P P+    + +P+     P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198

Query: 119  VATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGC 178
             AT        +GG A  +       +G     A       GG    P    A   P   
Sbjct: 1199 AATPPSP----KGGLATPSP------KGAPTTPAATPPSPKGGLAT-PSPKGAPTTPAAT 1247

Query: 179  PLGGEDPPGTP----AATPRAAC-------------CCAPQPAEDEPPAP---PAVCPRK 218
            P   +  P TP    A TP AA                AP PA   PP+P   PA  P K
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307

Query: 219  RCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPS 251
                     P   P+P  +P   P +    PP+
Sbjct: 1308 GAPTPPAATP---PSPKGSPGTPPPKGAPTPPA 1337



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 57/212 (26%), Positives = 71/212 (33%), Gaps = 24/212 (11%)

Query: 60   PAGTPAPP-PQQQPGEPAAGPPA---GWGEPPPPAARASWPETEPQPERSSVSDAPRVGD 115
            P G PA P P+  P  PAA PP+   G   PP   A  +   T P P+    +  P+   
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149

Query: 116  EVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRP 175
              P AT        +GG A          +G     A       GG    P    A   P
Sbjct: 1150 TTPAATPPSP----KGGLATPPP------KGAPTTPAATPPSPKGGLAT-PSPKGAPTTP 1198

Query: 176  CGCP---LGG------EDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGG 226
               P    GG      +  P TPAATP +       P+    P  PA  P          
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP 1258

Query: 227  GPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDA 258
             P G P P +      +  L  PP  G  + A
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 57/225 (25%), Positives = 72/225 (32%), Gaps = 43/225 (19%)

Query: 51   PCPGLYLAGPAGTPAPP---PQQQPGEPAAGPPAGWGEPPP-----PAARASWPETEPQP 102
            P  G   + P G P PP   P    G P   PP G   PP      P    + P T P  
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS 1356

Query: 103  ERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGW 162
            +    + + + G   P AT +  G                   GP         G A   
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHKG-------------------GPAMTPPSPKRGPA--- 1394

Query: 163  GVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAA 222
               P        P   PL  +  P TP     AA      P++ +   PPAV P     A
Sbjct: 1395 --IPSPKGDPTSPAVIPLSPKKAPATPVTREGAA-----TPSKGD-LTPPAVTPVSLKKA 1446

Query: 223  GVGGGPAGCPAPGSTPLKK--PRRNLEQPPSGGEDDDAEEMETGN 265
                 P G PA   TP  K  P      PPS  E    +++ T +
Sbjct: 1447 PATSAPKGGPA---TPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 58/215 (26%), Positives = 70/215 (32%), Gaps = 27/215 (12%)

Query: 53   PGLYLAGPAGTPAPPPQQ-QPGEPAAGPPA---GWGEPPPPAARASWPETEPQPERSSVS 108
            P   L  P G PA P  +  P  PAA PP+   G   P P  A      T P P+    +
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119

Query: 109  DAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFP-- 166
               +     P AT        +GG A          +G     A       GG    P  
Sbjct: 1120 PPHKGAPTTPAATPPSP----KGGLATPPP------KGAPTTPAATPPSPKGGLATPPPK 1169

Query: 167  --EVSRAARRPCGCPLGG------EDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRK 218
                + AA  P   P GG      +  P TPAATP +       P+    P  PA  P  
Sbjct: 1170 GAPTTPAATPP--SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227

Query: 219  RCAAGVGGGPAGCP-APGSTPLKKPRRNLEQPPSG 252
                     P G P  P +TP          PP G
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 53/200 (26%), Positives = 70/200 (35%), Gaps = 23/200 (11%)

Query: 58   AGPAGTPAPPPQQ-QPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDE 116
            + P G PA P  +  P  PA  PP+   EPP P   A+    +  P   +   AP +   
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSP-KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508

Query: 117  VPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPC 176
            +P +            +  A  A     + P   A +EA          P+ + A   P 
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568

Query: 177  GCPL--GGEDPPGTPAATPRAACCCAPQPAE------------DEPPAPPAVCPRKRCAA 222
              P     ++    PA TP +    AP P E             E P PPAV P      
Sbjct: 1569 EAPATPSSKEASSPPAVTP-STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP-----P 1622

Query: 223  GVGGGPAGCPAPGSTPLKKP 242
                GPA  PAP  TP   P
Sbjct: 1623 SPEKGPA-TPAPKGTPTSPP 1641



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 42/177 (23%), Positives = 58/177 (32%), Gaps = 29/177 (16%)

Query: 79   PPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATE 138
            PP+  G P P A     P+    P +           E P  +V  +    +G    A  
Sbjct: 858  PPSPKGAPTPSAVTPLSPKGVTLPPK-----------ETPTPSVVNLPFPKEGPATPA-- 904

Query: 139  AAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGG--EDPPGTPAATPRAA 196
                    P+QA A     ++      P+ +RA   P G P     +  P  PAATP + 
Sbjct: 905  --------PKQAPALSMTSSS------PKKARATPAPKGIPASPSPKGAPTPPAATPPSP 950

Query: 197  CCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGG 253
                  P+    P PPA  P           P G P P +     P+     P   G
Sbjct: 951  KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)

Query: 47   YLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSS 106
            Y   P P   L  PA T +P P++ P  PA  PP+    P  PA + +   T P    SS
Sbjct: 1590 YKGAPSPKELLIPPAVT-SPSPKEAPTPPAVTPPSPEKGPATPAPKGT--PTSPPVTPSS 1646

Query: 107  VSDAP--------RVGDEVPVAT 121
            + D+P        ++G  VP A+
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQAS 1669



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 14/76 (18%)

Query: 59   GPAGTPAPPP----QQQPGEPAAGPPAGW---GEPPPPAARASWPETE-------PQPER 104
            GP  T AP P    Q+   + A G  A     G   PP ++AS P T        P+PE 
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES 1787

Query: 105  SSVSDAPRVGDEVPVA 120
            +SVS AP     +P+A
Sbjct: 1788 ASVSAAPSPPVSLPLA 1803



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 45/198 (22%), Positives = 59/198 (29%), Gaps = 41/198 (20%)

Query: 60   PAGTPAPPPQQQPGEPAAGP-----PAGWGEPPPPAARASWPETEPQPERSSVSDAPRVG 114
            PA T +P P    G P         P G   PP      S     P P+    + AP+  
Sbjct: 850  PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL-PFPKEGPATPAPK-- 906

Query: 115  DEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARR 174
             + P  ++T                       P++A A  A     G    P    A   
Sbjct: 907  -QAPALSMTS--------------------SSPKKARATPAPK---GIPASPSPKGAPTP 942

Query: 175  PCGCPLGGEDPPGTP---------AATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVG 225
            P   P   +  P TP         AATP +       P+    P PPA  P         
Sbjct: 943  PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002

Query: 226  GGPAGCPAPGSTPLKKPR 243
              P G P P +     P+
Sbjct: 1003 PSPKGAPTPPAVTPPSPK 1020



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 11/73 (15%)

Query: 60   PAGTP-----APPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVG 114
            PA TP     AP P++    PA   P+    P PPA       T P PE+   + AP+  
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAV------TPPSPEKGPATPAPKGT 1636

Query: 115  DEVPVATVTGVGD 127
               P  T + + D
Sbjct: 1637 PTSPPVTPSSLKD 1649


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 80/290 (27%), Positives = 99/290 (34%), Gaps = 43/290 (14%)

Query: 57  LAGPAGTPA---PPPQQQPGEPAAGPPAGW--GEPPP--PAARASWPETE----PQPERS 105
           LA P   P     PP    G P  GP  G   GE PP  P A A+    E    P+   S
Sbjct: 341 LAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVAS 400

Query: 106 SVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGT------- 158
               A   GD  P  T           +  AT  A S  +GP ++  +EAE T       
Sbjct: 401 PFPTAIPEGDTTPPET-----------DPAATSEAPSARDGPERSVPKEAEPTPPVLPDE 449

Query: 159 -AGGWGVFPEVSRAARRPCGCPLG------GEDPPGTPAATPRAACCC---APQPAEDEP 208
             G  G  PE  R A        G      G +P   PA +P A   C    P  A + P
Sbjct: 450 EKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGP 509

Query: 209 PAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVAN 268
            A P +   +  +  V  GP    A  + P +      E PP+G E    E       A 
Sbjct: 510 AASPPLAAAE--SPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAE 567

Query: 269 LISIFGSSFSGL-LRKSPGGGREEEEGEESGPEAAEPGQICCDKPVLRDM 317
           L      S S    R  PG  R  E      P  A  G +   +  L D+
Sbjct: 568 LRGAKKFSVSSCRARPRPGVSRPLERASGRLP-LARSGPVWRSEAALDDL 616



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 71/282 (25%), Positives = 98/282 (34%), Gaps = 58/282 (20%)

Query: 67  PPQQQPGEPAAGPPAGWGEPPPPAARASWPE--TEPQPERSSVSDAPRVGDEVPVATVTG 124
           P +  P E    PP    E   P   A  PE   E +PER + ++  R+G E   A    
Sbjct: 431 PERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTA---- 486

Query: 125 VGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGED 184
                    A +  A  S ++  R AAA E      G    P ++ A           E 
Sbjct: 487 --------PAPSPPAPKSCLK-HRPAAASE------GPAASPPLAAA-----------ES 520

Query: 185 PPGTPAATPRAACCCAPQ-PAEDEPPAPPAVCPR-------KRCAAGVGGGP----AGC- 231
           PP  P      A   AP+ P  +   APPA   R       +R  A + G      + C 
Sbjct: 521 PPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCR 580

Query: 232 --PAPG-STPLKKPRRNLEQPPSG------GEDDDAEEMETGNVA----NLISIFGSSFS 278
             P PG S PL++    L    SG         DD + +     A      ++  G   S
Sbjct: 581 ARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDS 640

Query: 279 GLLRKSPGGGREEEEGEESGPEAAEPGQICCDKPVLRDMNPW 320
           G    SP G R+  +   + P   EP     +     D NP+
Sbjct: 641 GDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPF 682


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 66/225 (29%), Positives = 82/225 (36%), Gaps = 32/225 (14%)

Query: 53  PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAAR------ASWPETEPQ--PER 104
           PGL    P G+P PPP   P        AG     P A R      A+ PE+ P+  P R
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 105 SSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAARE--AEGTAGGW 162
           +S   A   G+  P A  T  G V   G A  T       +   + +A E  A G A   
Sbjct: 82  TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141

Query: 163 GVFPEVSRAARRPCGCPLGGEDPP---------GTPAATPRAACCCAPQP---------- 203
                +S  ARR    P  G   P         GT    PR A    P+P          
Sbjct: 142 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 201

Query: 204 -AEDEPPAPPAVCPRKRCAAGVG-GGPAGCPAPGS-TPLKKPRRN 245
            A +     P+   R+R +AG G   PA      S TPL  P R+
Sbjct: 202 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 47/202 (23%), Positives = 68/202 (33%), Gaps = 21/202 (10%)

Query: 53  PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPER-SSVSDAP 111
           P    A P   P  PP   P  P+A PP    + PPP A       +P P+   +++  P
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQLAKPPPQAPPALATPP 488

Query: 112 RVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRA 171
                 P A+  G            +  A    + P   AA   +         P  S  
Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS-----PPASPT 543

Query: 172 ARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGC 231
            + P   P  G   P T  + PR     AP      PP PP+  P    ++ + G     
Sbjct: 544 LQAPRRPPTPG---PDTSVSGPRLTLALAP-----GPPPPPSRSP----SSTLSGPDLAG 591

Query: 232 PAPGSTPLKKPRRNLEQPPSGG 253
            +  +T   +  R  +  P GG
Sbjct: 592 HSSSATSTPEELRGYDSGPEGG 613



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 57/223 (25%), Positives = 67/223 (30%), Gaps = 44/223 (19%)

Query: 57  LAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASW-------PETEPQPERSSVSD 109
           L  P   P  PP Q P  P A PP      PP  A  S        P + P     S S 
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 456

Query: 110 APRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFP--- 166
            P      P+A             A   + A    + P   A    +        FP   
Sbjct: 457 TPPPQAPPPLA-------------APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 503

Query: 167 EVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPA----VCPRKRCAA 222
             S +A  P   PL    PP  P A P  A      P    PP+PPA      PR+    
Sbjct: 504 PFSPSASLPMS-PLA--TPP--PQAPPVLAA-----PLLQVPPSPPASPTLQAPRRPPTP 553

Query: 223 GVGGGPAG-------CPAPGSTPLKKPRRNLEQPPSGGEDDDA 258
           G     +G        P P   P + P   L  P   G    A
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 596



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 42/149 (28%), Positives = 49/149 (32%), Gaps = 41/149 (27%)

Query: 56  YLAGPAGTPA--PPPQQQPGEPAAGPPAGW--GEPPP------PAARASWPETEPQPERS 105
           Y +GP G  A  PPP     E AA  PA W  G  PP      P A   WP         
Sbjct: 606 YDSGPEGGAAASPPPD---AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 662

Query: 106 SV-----SDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAARE------ 154
            +     ++ P      P A   G      GG+A A   A +    P+QA   E      
Sbjct: 663 GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 722

Query: 155 -----------------AEGTAGGWGVFP 166
                            AEG AGG G  P
Sbjct: 723 QASVVQHLLSRTLLLAAAEGAAGGSGGGP 751



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 46/173 (26%), Positives = 64/173 (36%), Gaps = 21/173 (12%)

Query: 84  GEPPPPAARASWPE-TEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWS 142
           G P P  AR S    TE    R + S  PR   E P  +V+   +      + A     S
Sbjct: 161 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 220

Query: 143 RVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQ 202
              G ++ A+R    +A        +S  AR        G    GTP A    +    P+
Sbjct: 221 AGGGLQRPASRSLSSSA------TPLSSPAR-------SGPSARGTPRAPAHPS---QPK 264

Query: 203 PAEDEPPAPPAVCP-RKRCAAGVG---GGPAGCPAPGSTPLKKPRRNLEQPPS 251
           P   +   PP V P RK  A  +G     P   P+P + P      +L+  PS
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 52/198 (26%), Positives = 67/198 (33%), Gaps = 21/198 (10%)

Query: 56  YLAGPAGTP-APPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVG 114
           +L  P  +P A PP Q P  PA   P     P PPA+    P   P P+      AP   
Sbjct: 341 FLPSPPLSPLATPPPQAP--PALALPPLQAPPSPPASPPLSPLATPSPQ------APN-- 390

Query: 115 DEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARR 174
                  V  +   F    +   +A +S    P  + +      A      P +      
Sbjct: 391 ----ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446

Query: 175 PCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCP-- 232
           P   P+     P   A  P AA     Q A+  P APPA+      A  +   PA  P  
Sbjct: 447 PASPPMSPSATPPPQAPPPLAA--PPLQLAKPPPQAPPALATPPLQA--LPSPPASFPGQ 502

Query: 233 APGSTPLKKPRRNLEQPP 250
           AP S     P   L  PP
Sbjct: 503 APFSPSASLPMSPLATPP 520



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 24/76 (31%), Positives = 25/76 (32%), Gaps = 13/76 (17%)

Query: 188 TPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVG-----------GGPAGCPAPGS 236
           TPAA  RA     P+P     P PP      R     G           GG  G   P S
Sbjct: 16  TPAA--RAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 237 TPLKKPRRNLEQPPSG 252
            P   P R    P SG
Sbjct: 74  APRAGPTRTSRPPASG 89


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 75/265 (28%), Positives = 91/265 (34%), Gaps = 60/265 (22%)

Query: 53   PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPR 112
            P    AGP   P PPP   P EP     A     PPP   A  P   P      VS  P 
Sbjct: 1181 PASEQAGPPELPPPPP---PAEPPPTDLAHLPPLPPPEGEARKPAKPP------VSPKPV 1231

Query: 113  VGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAA 172
            +   VP           QG     ++     + GP     + A GT       P     A
Sbjct: 1232 LTQPVP---------KLQGSPTPTSKKV--PLPGPGSPEVKRAHGTPPPVSPKPPPPPTA 1280

Query: 173  RRP----CGCPLG--GEDPPGTPAATPRAACCCAP--------QPAEDEPPAPPAV-CPR 217
             +P     G P G  G  P  +PA  P AA    P         PA+   P  PA+  P 
Sbjct: 1281 PKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPA 1340

Query: 218  K--RCAAGVGGGPAGCPAP--GSTPLKKPRRNLE------------------QPPSGGED 255
            K  R AA      A  PAP  G++P    R+ LE                  Q  + G  
Sbjct: 1341 KPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPR 1400

Query: 256  DDAEEMETGNVANLISIFGSSFSGL 280
            D A E  TG++ + I   GS F  L
Sbjct: 1401 DSAAEKSTGSILDDI---GSMFDDL 1422



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 5/36 (13%)

Query: 58  AGPAGTPAPPPQQQPGEPAAGPPAG-----WGEPPP 88
           +GP  +PA PP+   G   + PP       +GE PP
Sbjct: 427 SGPGDSPAKPPEGSAGVARSQPPVAHAGQVYGEQPP 462


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 68/238 (28%), Positives = 89/238 (37%), Gaps = 37/238 (15%)

Query: 53  PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPR 112
           PG + +G AGT AP P   PGEP   P  G  +P    ++ S    +P+P R +  DA  
Sbjct: 257 PGAHASGAAGT-APAP---PGEP---PAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAAS 309

Query: 113 VGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAA 172
            G    VA V             + E+  S     R+AA+  A   A G    P +  A 
Sbjct: 310 CGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAP 369

Query: 173 RR----------PCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAA 222
           R           P   PLG   P    A    A    AP+ A   P  PPA  P  + + 
Sbjct: 370 RTLIGKGHFLLYPITQPLGFLVPQA--ALKGGAGLEPAPKDAPPAPAVPPA--PPAQASF 425

Query: 223 GVGGGPAGCP-------------APGS-TPLKKPRRNLEQPPS--GGEDDDAEEMETG 264
           G   GP G P             +PG+  P   P R+L    +  GG  D A+    G
Sbjct: 426 GAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAG 483



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 45/167 (26%), Positives = 53/167 (31%), Gaps = 50/167 (29%)

Query: 50  DPCPGLYLAGPAGTPAPPPQQQPGE---PAAGPPAGWGEPPPPA-ARASWPETEPQPERS 105
           +P P      PA  PAPP Q   G    P   P + +    P A A    P   P P R 
Sbjct: 403 EPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRD 462

Query: 106 SVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVF 165
             S A                   +GG  D  +A                 GTAG     
Sbjct: 463 LASAAAT-----------------EGGGGDCADA-----------------GTAGP---- 484

Query: 166 PEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPP 212
                A   P   P  G  PP +PA  P  A C  P+P     P+PP
Sbjct: 485 -----APPPPAPSPRPGPRPP-SPAEEP--ATCGVPEPGAAAGPSPP 523



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 21/49 (42%), Positives = 22/49 (44%), Gaps = 8/49 (16%)

Query: 58  AGPAGTPAPPPQQQPGEPAAGPPAGWGEP-------PPPAARASWPETE 99
           AG AG PAPPP      P   PP+   EP       P  AA  S PE E
Sbjct: 479 AGTAG-PAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGE 526



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 45/176 (25%), Positives = 58/176 (32%), Gaps = 45/176 (25%)

Query: 53  PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPR 112
           P   L G AG   P P+  P  PA  PPA    PP  A+  ++      P+ +    +P 
Sbjct: 392 PQAALKGGAGLE-PAPKDAPPAPAV-PPA----PPAQASFGAFSGPGGAPDSAFARRSP- 444

Query: 113 VGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAA 172
                               +A A+  A +    P +  A  A  T GG G   +   A 
Sbjct: 445 --------------------DAVASPGAPAPAPAPFRDLA-SAAATEGGGGDCADAGTAG 483

Query: 173 RRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGP 228
             P         PP  PA +PR      P P    P   PA C      A  G  P
Sbjct: 484 PAP---------PP--PAPSPR------PGPRPPSPAEEPATCGVPEPGAAAGPSP 522


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 68/280 (24%), Positives = 89/280 (31%), Gaps = 39/280 (13%)

Query: 53  PGLYLAGPAGTPAPP-------PQQQPGEPAAGPPAGWGEP--PPPAARASWPETEPQPE 103
           P L    P G P+P        P   PG+P   PP G  +P  PPP  +   P     P 
Sbjct: 29  PSLIAGNPQG-PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-----PP 82

Query: 104 RSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWG 163
           +   S +PR     P       G+  QG      +      +G  +       G   G  
Sbjct: 83  QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142

Query: 164 VFPEVSRAARRPCG-----CPLGGEDPPGTP-------AATPRAACCCAPQPAEDEPPAP 211
              + SR+ R P G      P GG  P G P          P+        P   +P  P
Sbjct: 143 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP 202

Query: 212 PAVCPRKRCAAGVGGGPAGCPAPGST----PLKKPRRNLEQPPSGGEDDDAEE---METG 264
           P    + R +    G P G P  G      P   P +    PP GG             G
Sbjct: 203 PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 262

Query: 265 NVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAEP 304
             A      G S S   R  PG  +   + E + P+   P
Sbjct: 263 PPAQ-----GGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 297



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 51/189 (26%), Positives = 67/189 (35%), Gaps = 28/189 (14%)

Query: 60  PAGTPAPPPQQ----------QPGEPAAGPPAGWGEP--PPPAARASWPETEPQPERSSV 107
           P G P  PP Q           PG+P   PP G  +P  PPP  +   P  +    RSS 
Sbjct: 154 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ 213

Query: 108 SDAPRVGDEVPVATVTGVGDVFQGGEADATEA-AWSRVEGPRQAAAREAEGTAGGWGVFP 166
           S   +     P       G     G+         ++ +GP      +     GG     
Sbjct: 214 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG----- 268

Query: 167 EVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPA---EDEPPAPPAVCPRKRCAAG 223
             S++AR P G P G   PP      P+      P PA     +P APPA  P+      
Sbjct: 269 SKSQSARSPPGKPQG---PPQQEGNNPQG----PPPPAGGNPQQPQAPPAGQPQGPPRPP 321

Query: 224 VGGGPAGCP 232
            GG P+  P
Sbjct: 322 QGGRPSRPP 330


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 58/203 (28%), Positives = 73/203 (35%), Gaps = 27/203 (13%)

Query: 51   PCPGLYLAG-----PAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERS 105
            P P  YLA        G P PP  + P E     P  W       A+   P  + +P + 
Sbjct: 829  PPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKE 888

Query: 106  SVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVF 165
                A   G E       GVG   QG      E+      GPR  ++R         G+ 
Sbjct: 889  ET--AQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRR--------GIP 938

Query: 166  PEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAE--DEPPAPPAVCPRKRCAAG 223
            PE   A  R  G P+    PP      P       P+P E  DE P PP   P K    G
Sbjct: 939  PEEPGAPPRRAG-PIKKPPPPTKVEELP-------PKPLEQGDETPKPPKPDPLK-ITKG 989

Query: 224  VGGGPAGCPAPGS-TPLKKPRRN 245
              GGP   P  G+ +P  + RR+
Sbjct: 990  KLGGPKETPPNGNLSPAPRLRRD 1012



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 72/254 (28%), Positives = 89/254 (35%), Gaps = 52/254 (20%)

Query: 50  DPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSD 109
           DP  GL    P+G P  PP +    P   PP     P PP      P   P P+    S 
Sbjct: 230 DPRGGLQ---PSGPPQFPPYRGMMPPFMYPPY---LPFPPPYGPQGPYRYPTPD--GPSR 281

Query: 110 APRV----GDEVPVATVTGVG---------------------DVFQGG--EADATEAA-W 141
            PRV    G   P+  V  VG                     D + G   E D TE   +
Sbjct: 282 FPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKF 341

Query: 142 SRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAP 201
           S  E  R +    AEG           S   R P      G  P   P  TP+ A     
Sbjct: 342 SDEEDGRDSDEEGAEGHRDS----QSASGEERPPEADGKKGNSPNSEPP-TPKTAWAETS 396

Query: 202 QPAEDEP--PAP-PAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDA 258
           +P E EP  PAP P + P  R  AG  G P   P  G  P K        PP+  ++D+A
Sbjct: 397 RPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCK--------PPAPEDEDEA 448

Query: 259 EEMETGNVANLISI 272
                   ++ IS+
Sbjct: 449 WRQRRKQSSSEISL 462



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 41/155 (26%), Positives = 55/155 (35%), Gaps = 18/155 (11%)

Query: 58  AGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEV 117
           A PA  PA P    P  P A P      P PP A A  PETEP+      + AP      
Sbjct: 506 AEPAAPPAAP--STPAPPPAVPKELPAPPAPPPASAPTPETEPE----EPAQAP-PAQST 558

Query: 118 PVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCG 177
           P   V     +  GG + ++ ++ S    P +      EG        PE       P  
Sbjct: 559 PTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEG--------PEPPEEVPPPTT 610

Query: 178 CPLGGEDPPGT---PAATPRAACCCAPQPAEDEPP 209
            P+   +P G    P   P +     P+  +  PP
Sbjct: 611 PPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPP 645



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 62/246 (25%), Positives = 79/246 (32%), Gaps = 50/246 (20%)

Query: 62  GTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVAT 121
           G PAP P   P  P  GP   WG P     R   P   P PE           DE     
Sbjct: 404 GPPAPKPPLPP--PHRGPAGNWGPPGDYPDRGGPPCKPPAPE-----------DE----- 445

Query: 122 VTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLG 181
                + ++     ++      VE  R+    E             +    R  C   L 
Sbjct: 446 ----DEAWRQRRKQSSSEISLAVERARRRREEEER----------RMQEERRAACAEKLK 491

Query: 182 GEDPP-GTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLK 240
             D   G P    +A    A  PA    PAPP   P++  A      PA  PA   TP  
Sbjct: 492 RLDEKFGAPDKRLKAE--PAAPPAAPSTPAPPPAVPKELPAP-----PAPPPASAPTPET 544

Query: 241 KPRRNLEQPPSGGEDDDAEEMETGNVA---NLISIFGSSFSGLLRKSPGGGREEEEGEES 297
           +P    + PP       A+   T  VA    L+S  GS+ S           E +   + 
Sbjct: 545 EPEEPAQAPP-------AQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKE 597

Query: 298 GPEAAE 303
           GPE  E
Sbjct: 598 GPEPPE 603



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 20/45 (44%), Positives = 21/45 (46%), Gaps = 2/45 (4%)

Query: 60   PAGTPAPPP-QQQPGEPAAGPPAGWGEPPP-PAARASWPETEPQP 102
            PA  PAPPP    P  PA  PP+    PPP PA R       P P
Sbjct: 1998 PAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFP 2042


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 61/219 (27%), Positives = 78/219 (35%), Gaps = 38/219 (17%)

Query: 33  NLLVSLVLRSARQVYLSDPCPGLY-LAGPAGTPAPPPQQQPGEPAA-----GPPAGWGEP 86
           NLL S    SA         P LY  +G A  P PP +  P +         P +    P
Sbjct: 246 NLLAS---SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPP 302

Query: 87  PPPAARA---------SWPETEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADAT 137
           PPP A A         S+P       R++++ +P  G E       G G+  + G + AT
Sbjct: 303 PPPPAHALQHYLSCGGSYPS---MGHRANLACSPLGGGEPS----PGAGEPSKAGPSGAT 355

Query: 138 EAAWSRVEGPRQAAAREAEGTAGGWGVFPEVS----RAARRPCGCPLGGEDPPGTPAATP 193
             A  R  GP  A    A G  GG G  P +     +  +   G   GG   P  P +T 
Sbjct: 356 AGASGRATGPEAAGGGGAGG--GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTA 413

Query: 194 RAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCP 232
              C     PA        A    K   AG  GG A  P
Sbjct: 414 TPKCQSLGGPA-------AAYATGKASGAGGAGGQAYSP 445



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 66/273 (24%), Positives = 106/273 (38%), Gaps = 37/273 (13%)

Query: 60   PAGTPAPPPQQQP---GEPAAGPPAGWGEPPPPAAR--------ASWPETEPQPERSSVS 108
            P G P   P + P   G  +A  P    + P    R        A     EP        
Sbjct: 1170 PRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKL 1229

Query: 109  DAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSR--VEGP-RQAAAREAEGTAGGWGVF 165
              P+ G+ +     T  GD   G + ++ +++ +R  +E   ++   ++ E  +G    F
Sbjct: 1230 SVPKAGEGLG----TSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASF 1285

Query: 166  PEVSRAARRPCGCPLGGEDPP-GTPAATPRAACCCAPQPAEDEPPAPPAVC-PRKRCAAG 223
             +  ++ +R       G  PP   P + P +      QP   +PPA PAV  P    A G
Sbjct: 1286 LDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQP---QPPATPAVPHPPPSGAFG 1342

Query: 224  VGGG---------PAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVANLISIFG 274
            +GG            GCP+P     ++ +RNLE  PS   D++    +  ++   IS   
Sbjct: 1343 LGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESIS--- 1399

Query: 275  SSFSGLLRKSPGGGREEE--EGEESGPEAAEPG 305
            S+ S L      G ++    +G    P AA PG
Sbjct: 1400 SAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG 1432



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 58/233 (24%), Positives = 79/233 (33%), Gaps = 43/233 (18%)

Query: 53   PGLYLAGPAGTPAPPPQQQPGEPAAG----PPAGWGEPPPPAARA-------SWPETE-- 99
            P LY AG     +PP    P  PA G    PPA    P PP + A          E+E  
Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGL 1355

Query: 100  ----PQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEA-DATEAAWSRVEGPRQAAARE 154
                P P +    +  R  + +P  +      V +  +  ++  +A S ++ P  A  ++
Sbjct: 1356 GLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKD 1415

Query: 155  AEGTAGGWGVFPEVSRAARRPCGCPLGG----------------EDPPGTPAATPRAACC 198
                 G     P ++ AA  P   PL G                E PP TP   P     
Sbjct: 1416 TSTPDG-----PPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ-- 1468

Query: 199  CAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPS 251
              PQP    PP  PA+       A     P   P P   P   P      PP+
Sbjct: 1469 --PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPA 1519



 Score = 36.6 bits (83), Expect = 0.031
 Identities = 23/65 (35%), Positives = 24/65 (36%), Gaps = 13/65 (20%)

Query: 51   PCPGLYLAGPAGTPAPP-------------PQQQPGEPAAGPPAGWGEPPPPAARASWPE 97
            P PGL  A   GTP PP             P  QP  P   PP     P PP   A  P 
Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPS 1494

Query: 98   TEPQP 102
            + P P
Sbjct: 1495 SPPPP 1499



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 38/143 (26%), Positives = 46/143 (32%), Gaps = 25/143 (17%)

Query: 51   PCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDA 110
            P P L    P   P P     P  P   PPA    PPPP   A+     P+   +   + 
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537

Query: 111  PRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPE--- 167
            P + D  P+            GE D                  E  G +GG G+F E   
Sbjct: 1538 PELPDTRPLHLAKKQETAAVCGETD------------------EEAGESGGEGIFRERDE 1579

Query: 168  -VSRAARRP---CGCPLGGEDPP 186
             V RA   P        G E PP
Sbjct: 1580 FVIRAEDIPSLKLALQTGREPPP 1602



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 43/164 (26%), Positives = 60/164 (36%), Gaps = 14/164 (8%)

Query: 64   PAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPE---RSSVSDAPRVGDEVPVA 120
            P PP    PG+   GPP   G+ P  A R+  P+    P     +S+     +  +   +
Sbjct: 889  PLPPA---PGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERS 945

Query: 121  TVTGVGDVFQGGEA-DATEAAWSRVEGPRQAAAREAEGTAG--GWGVF--PEVSRAARRP 175
                + ++F GG A D  +A     EG  +A A    G      +G +     S A    
Sbjct: 946  FFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPET 1005

Query: 176  CGCPLGGEDPPGTPA---ATPRAACCCAPQPAEDEPPAPPAVCP 216
             G  L    PP  P+   A P       P  A   PP PP   P
Sbjct: 1006 PGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPP 1049



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 40/157 (25%), Positives = 54/157 (34%), Gaps = 31/157 (19%)

Query: 58   AGPAGTPAPPPQQQPGE-------PAAGPPAGWGEPPPPAARASWPETEPQPERSSVS-- 108
            A P   PAPPP+ +  E       P   P     EPP P   +     E + E+  V+  
Sbjct: 1691 APPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRG 1750

Query: 109  DAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSR-----VEGP---RQAAAREAEG--T 158
            + P  G+       T        G+   +    +R      E P   R+   +EA G  T
Sbjct: 1751 ERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNAT 1810

Query: 159  AGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRA 195
            AGG             P G     E  PG P+   RA
Sbjct: 1811 AGG------------GPPGSSSDSESSPGAPSEDERA 1835



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 5/54 (9%)

Query: 49   SDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPP--PPAARASWPETEP 100
            S P P L    P   P+PPP   P  PAA P A   E P  P       P+T P
Sbjct: 1495 SPPPPPLPPPPPPAMPSPPP---PPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 46/209 (22%), Positives = 58/209 (27%), Gaps = 70/209 (33%)

Query: 57   LAGPAGTPAPPPQQQPGEPAAGPPAGWGEPP-----PPAARASWPETEPQPERSSVSDAP 111
            LA  A  P PPP   PG P+A    G  EPP     PP      P  +PQP        P
Sbjct: 1424 LAPAAAVPGPPPL--PGLPSANSN-GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQP 1480

Query: 112  RVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRA 171
             +    P+                                                V+  
Sbjct: 1481 ALPSPPPL------------------------------------------------VAPT 1492

Query: 172  ARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGC 231
               P   PL    PP  P+  P      AP  A  E PA P+              P   
Sbjct: 1493 PSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS--------------PEDP 1538

Query: 232  PAPGSTPLKKPRRNLEQPPSGGEDDDAEE 260
              P + PL   ++       G  D++A E
Sbjct: 1539 ELPDTRPLHLAKKQETAAVCGETDEEAGE 1567



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 2/35 (5%)

Query: 54   GLYLAGP--AGTPAPPPQQQPGEPAAGPPAGWGEP 86
            GL  +GP  A  P PPP   P  PA+ P  G   P
Sbjct: 1028 GLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 32/125 (25%), Positives = 38/125 (30%), Gaps = 32/125 (25%)

Query: 185 PPGTPAATPRAACCCA----PQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLK 240
           PP    A PR          P  A+  PP PPA   +   + G           GS P  
Sbjct: 275 PPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCG-----------GSYPSM 323

Query: 241 KPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPE 300
             R NL   P GG +      E                   +  P G      G  +GPE
Sbjct: 324 GHRANLACSPLGGGEPSPGAGEPS-----------------KAGPSGATAGASGRATGPE 366

Query: 301 AAEPG 305
           AA  G
Sbjct: 367 AAGGG 371



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 44/175 (25%), Positives = 62/175 (35%), Gaps = 38/175 (21%)

Query: 66   PPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDE--VPVATVT 123
            P P ++ G+      AG    PPP A A  P+ E  PE+++    P    E  +P     
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPE-TPEKTTSEKPPEQTPETAMPEPPAP 1729

Query: 124  GVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGE 183
                + +  E +  +   +R E P +      E    G    PE S A  +P    L   
Sbjct: 1730 EKPSLLRPVEKEKEKEKVTRGERPLR-----GERATSGRQTRPERSLATGQPATSRL--- 1781

Query: 184  DPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCA--------AGVGGGPAG 230
                     P+A     P   + EPP      P+KR          A  GGGP G
Sbjct: 1782 ---------PKA----RPTKVKAEPP------PKKRKKWLKEAGGNATAGGGPPG 1817


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 48/170 (28%), Positives = 58/170 (34%), Gaps = 32/170 (18%)

Query: 58  AGPAGTPAPPPQ------QQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAP 111
           A PA  P PPP       + PG PA GPP      PPPAA  +       P     + AP
Sbjct: 264 AAPAAAPPPPPPAPATLARPPGHPA-GPPTAAPAVPPPAAAQNGGSAGAAP-----APAP 317

Query: 112 RVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQA-----------AAREAEGTAG 160
             G    V+   G       G A A  A   + E P++            AA     TA 
Sbjct: 318 AAGGPAGVSGQPG------PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAA 371

Query: 161 GWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPA 210
              + P +  A   P   P      PGTP   P+ A     Q     P A
Sbjct: 372 SMVIGPTMQGALPSPAAVP---PPAPGTPTGLPKGAAGAVTQSLSRTPTA 418



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 54/199 (27%), Positives = 66/199 (33%), Gaps = 22/199 (11%)

Query: 64  PAPPPQQQPGEPAA-GPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATV 122
           P PP  ++P  PA   PPA    PPP  +  S     P P  ++V+  P      P    
Sbjct: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS---CAPVPAAAAVAAGPEPAPAGPAKPA 161

Query: 123 TGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVF--------PEVSRAARR 174
                  + G             GP + A   A  T  G            P VS     
Sbjct: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221

Query: 175 PCG-CPLGGEDPPGTPAATPR-AACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCP 232
           P    PL     PGT   TP        P PA   PPA PA       AA     P   P
Sbjct: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAP------AAPAAAPPPPPP 275

Query: 233 APGSTPLKKPRRNLEQPPS 251
           AP +  L +P  +   PP+
Sbjct: 276 APAT--LARPPGHPAGPPT 292



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 60/231 (25%), Positives = 67/231 (29%), Gaps = 74/231 (32%)

Query: 60  PAGTPAPPPQ----------QQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSD 109
           P   P PPP           Q+PG P+   P     P PPAA+       P PE S+ S 
Sbjct: 83  PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL-----RPPPEGSAGSC 137

Query: 110 APRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWG------ 163
           AP     VP A     G        +   A  ++  GP   AAR   G   G G      
Sbjct: 138 AP-----VPAAAAVAAGP-------EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185

Query: 164 -------------------------VFPEVSRAARRPCGC-PLGGEDPPGTPAATPRAAC 197
                                      P VS     P    PL     PGT   TP    
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245

Query: 198 CCAPQ---------------PAEDEPPAPPAVCPRKRCAAGVGGGPAGCPA 233
             AP                PA   PP PPA     R      G P   PA
Sbjct: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPA 296



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 60/207 (28%), Positives = 70/207 (33%), Gaps = 27/207 (13%)

Query: 58  AGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETE--PQPERSSVSDAPRVGD 115
           AGP   P P P   PG    G PAG G        A+   +     P  S V++ P    
Sbjct: 170 AGPGPGPGPGPGPGPGP---GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALL 226

Query: 116 EVPVATVTGV---GDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAA 172
            +P     G       F G  A    AA S    P  AA   A          P      
Sbjct: 227 PLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP------PPAPATL 280

Query: 173 RRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGP---- 228
            RP G P G   P   PA  P AA            PAP A  P     AGV G P    
Sbjct: 281 ARPPGHPAG--PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP-----AGVSGQPGPGA 333

Query: 229 -AGCPAPGSTPLKKPRRNLEQPPSGGE 254
            A  PAPG    + P+R ++  P   +
Sbjct: 334 AAAAPAPG-VKAESPKRVVQAAPPAAQ 359



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 48/173 (27%), Positives = 55/173 (31%), Gaps = 19/173 (10%)

Query: 59  GPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVP 118
           G A  PAP     P  PA   PA    PPPPA     P T  +P     +  P     VP
Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA-----PATLARPP-GHPAGPPTAAPAVP 298

Query: 119 VATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTA------GGWGVFPEVSRAA 172
                       GG A A  A      GP   + +   G A      G     P+    A
Sbjct: 299 PPAAAQ-----NGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA 353

Query: 173 RRPCGCPLGGEDPPGTPAATPRAACC--CAPQPAEDEPPAPPAVCPRKRCAAG 223
             P    L    P  T A+           P PA   PPAP       + AAG
Sbjct: 354 APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAG 406



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 55/161 (34%), Positives = 58/161 (36%), Gaps = 46/161 (28%)

Query: 110 APRVGDEVPVATVTGVGD-VFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEV 168
           APR   EV  A    +G+ V  G  A A  A      GP    A  AEG  G     P  
Sbjct: 44  APRT-PEVRAAAAGALGNHVVSGSPAGAAGA------GP----AAPAEGAPGAAPEPPPA 92

Query: 169 SRAARRPCGCPLGGEDPPGTPA----------ATPRA---------ACCCAPQPAE---- 205
            RA  RP G   GG   PG P+          A P A         A  CAP PA     
Sbjct: 93  GRA--RPGG---GGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVA 147

Query: 206 --DEP----PAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLK 240
              EP    PA PA        AG G GP   P PG  P K
Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 63/232 (27%), Positives = 79/232 (34%), Gaps = 32/232 (13%)

Query: 52   CPGLYLAGPAGTPAPPPQQQPGEPAAGP-PAGWGEPPPPAARAS---WPETE--PQPERS 105
            C     A P   P PPPQ  P      P PA    P  P  RAS   W  T+    P  +
Sbjct: 896  CCSAEAAPPPAKPPPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGA 955

Query: 106  SVSDA--PRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWG 163
             ++D      G   P     G+G+        A   A  R   P   AA+  +     + 
Sbjct: 956  GLADGFHRYYGPIEPQGLGLGLGEA-----RAAPRGAAGRPLSP--PAAQPPQKPPPSYF 1008

Query: 164  VFPEVSRAARRPCGCPLGGEDPPGTPAATPRAA--CCCAPQPAEDEPPAP---------- 211
                    A  P G   G   PP  PAA   A     C     ++ PPAP          
Sbjct: 1009 AIVRDKEPAEPPAGAFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAPARWPRSDPES 1068

Query: 212  -PAVCPRKRCAAGVGGGPAGCPAP----GSTPLKKPRRNLEQPPSGGEDDDA 258
             P + P    A G GG   G PA      + P   P  +LE  PS  ED ++
Sbjct: 1069 QPLLGPGAGGAGGTGGAGGGAPAAPPPCRAAPPPCPYLDLEPSPSDSEDSES 1120



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 42/155 (27%), Positives = 47/155 (30%), Gaps = 30/155 (19%)

Query: 67   PPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVG 126
            PP +       G   GW  PPPP   A      P P R +    PR     P A      
Sbjct: 1190 PPPRHLSCSHDGLDGGWWAPPPPPWAAG-----PLPRRRARCGCPRSHPHRPRA------ 1238

Query: 127  DVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFP--EVSRAARRPCGCPLGGED 184
                   +  T AA      P     R A   AGGW + P    SR+      CP     
Sbjct: 1239 -------SHRTPAA----AAPHHHRHRRA---AGGWDLPPPAPTSRSLEDLSSCPRAA-- 1282

Query: 185  PPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKR 219
             P      P       P  A   PP P A   R R
Sbjct: 1283 -PARRLTGPSRHARRCPHAAHWGPPLPTASHRRHR 1316


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 51/191 (26%), Positives = 69/191 (36%), Gaps = 24/191 (12%)

Query: 70  QQPGEPAAGPPAGWGEPPPPAARASWPETEPQ---PERSSVSDAPRVGDEVPVATVTGVG 126
           ++ G P    P    EP         P+ + +    E+    DA    +E P A      
Sbjct: 32  EEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKA------ 85

Query: 127 DVFQGGEADATEAAWSRVEGPRQAAARE--AEGTAGGWGVFPEVSRAARRPC--GCPLGG 182
                 E + TE A      P +A  +E  A G A G G  P+ + AA  P     P  G
Sbjct: 86  ------EPEKTEGAAEAKAEPPKAPEQEQAAPGPAAG-GEAPKAAEAAAAPAESAAPAAG 138

Query: 183 EDPP---GTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTP- 238
           E+P    G P  T   A   A +   D  PA  +       A      PA   AP STP 
Sbjct: 139 EEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPK 198

Query: 239 LKKPRRNLEQP 249
            + P  + E+P
Sbjct: 199 AQGPAASAEEP 209



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 46/148 (31%), Positives = 54/148 (36%), Gaps = 27/148 (18%)

Query: 59  GPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVP 118
           G A   A PP+    E AA  PA  GE P  A  A+ P         + S AP  G+E  
Sbjct: 92  GAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAP---------AESAAPAAGEEPS 142

Query: 119 VATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGT-AGGWGVFPEVSRAARRPCG 177
                      + GE   TEA       P   AA+E +   A      P  S AA     
Sbjct: 143 K----------EEGEPKKTEA-------PAAPAAQETKSDGAPASDSKPGSSEAAPSSKE 185

Query: 178 CPLGGEDPPGTPAATPRAACCCAPQPAE 205
            P   E P  TP A   AA    P+P E
Sbjct: 186 TPAATEAPSSTPKAQGPAASAEEPKPVE 213


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 67/234 (28%), Positives = 82/234 (35%), Gaps = 41/234 (17%)

Query: 53  PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAAR------ASWPETEPQ--PER 104
           PGL    P G+P PPP   P        AG     P A R      A+ PE+ P+  P R
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 105 S---------SVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAARE- 154
           S         S   A   G+  P A  T  G V   G A  T       +   + +A E 
Sbjct: 82  SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141

Query: 155 -AEGTAGGWGVFPEVSRAARRPCGCPLGGEDPP---------GTPAATPRAACCCAPQP- 203
            A G A        +S  ARR    P  G   P         GT    PR A    P+P 
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201

Query: 204 ----------AEDEPPAPPAVCPRKRCAAGVG-GGPAGCPAPGS-TPLKKPRRN 245
                     A +     P+   R+R +AG G   PA      S TPL  P R+
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 47/202 (23%), Positives = 68/202 (33%), Gaps = 21/202 (10%)

Query: 53  PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPER-SSVSDAP 111
           P    A P   P  PP   P  P+A PP    + PPP A       +P P+   +++  P
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQLAKPPPQAPPALATPP 527

Query: 112 RVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRA 171
                 P A+  G            +  A    + P   AA   +         P  S  
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS-----PPASPT 582

Query: 172 ARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGC 231
            + P   P  G   P T  + PR     AP      PP PP+  P    ++ + G     
Sbjct: 583 LQAPRRPPTPG---PDTSVSGPRLTLALAP-----GPPPPPSRSP----SSTLSGPDLAG 630

Query: 232 PAPGSTPLKKPRRNLEQPPSGG 253
            +  +T   +  R  +  P GG
Sbjct: 631 HSSSATSTPEELRGYDSGPEGG 652



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 57/223 (25%), Positives = 67/223 (30%), Gaps = 44/223 (19%)

Query: 57  LAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASW-------PETEPQPERSSVSD 109
           L  P   P  PP Q P  P A PP      PP  A  S        P + P     S S 
Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 495

Query: 110 APRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFP--- 166
            P      P+A             A   + A    + P   A    +        FP   
Sbjct: 496 TPPPQAPPPLA-------------APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 542

Query: 167 EVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPA----VCPRKRCAA 222
             S +A  P   PL    PP  P A P  A      P    PP+PPA      PR+    
Sbjct: 543 PFSPSASLPMS-PLA--TPP--PQAPPVLAA-----PLLQVPPSPPASPTLQAPRRPPTP 592

Query: 223 GVGGGPAG-------CPAPGSTPLKKPRRNLEQPPSGGEDDDA 258
           G     +G        P P   P + P   L  P   G    A
Sbjct: 593 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 42/149 (28%), Positives = 49/149 (32%), Gaps = 41/149 (27%)

Query: 56  YLAGPAGTPA--PPPQQQPGEPAAGPPAGW--GEPPP------PAARASWPETEPQPERS 105
           Y +GP G  A  PPP     E AA  PA W  G  PP      P A   WP         
Sbjct: 645 YDSGPEGGAAASPPPD---AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701

Query: 106 SV-----SDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAARE------ 154
            +     ++ P      P A   G      GG+A A   A +    P+QA   E      
Sbjct: 702 GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 761

Query: 155 -----------------AEGTAGGWGVFP 166
                            AEG AGG G  P
Sbjct: 762 QASVVQHLLSRTLLLAAAEGAAGGSGGGP 790



 Score = 32.0 bits (71), Expect = 0.77
 Identities = 52/198 (26%), Positives = 67/198 (33%), Gaps = 21/198 (10%)

Query: 56  YLAGPAGTP-APPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVG 114
           +L  P  +P A PP Q P  PA   P     P PPA+    P   P P+      AP   
Sbjct: 380 FLPSPPLSPLATPPPQAP--PALALPPLQAPPSPPASPPLSPLATPSPQ------APN-- 429

Query: 115 DEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARR 174
                  V  +   F    +   +A +S    P  + +      A      P +      
Sbjct: 430 ----ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485

Query: 175 PCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCP-- 232
           P   P+     P   A  P AA     Q A+  P APPA+      A  +   PA  P  
Sbjct: 486 PASPPMSPSATPPPQAPPPLAA--PPLQLAKPPPQAPPALATPPLQA--LPSPPASFPGQ 541

Query: 233 APGSTPLKKPRRNLEQPP 250
           AP S     P   L  PP
Sbjct: 542 APFSPSASLPMSPLATPP 559


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 67/234 (28%), Positives = 82/234 (35%), Gaps = 41/234 (17%)

Query: 53  PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAAR------ASWPETEPQ--PER 104
           PGL    P G+P PPP   P        AG     P A R      A+ PE+ P+  P R
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 105 S---------SVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAARE- 154
           S         S   A   G+  P A  T  G V   G A  T       +   + +A E 
Sbjct: 82  SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141

Query: 155 -AEGTAGGWGVFPEVSRAARRPCGCPLGGEDPP---------GTPAATPRAACCCAPQP- 203
            A G A        +S  ARR    P  G   P         GT    PR A    P+P 
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201

Query: 204 ----------AEDEPPAPPAVCPRKRCAAGVG-GGPAGCPAPGS-TPLKKPRRN 245
                     A +     P+   R+R +AG G   PA      S TPL  P R+
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 54/195 (27%), Positives = 66/195 (33%), Gaps = 20/195 (10%)

Query: 64  PAPPPQQQPGEPAAGP----PAGWGEPPP--PAARASWP-ETEPQPERSSVSDAPRVGDE 116
           PAP P Q P  P   P    P+    PPP  P A AS P +  P P  S ++  P     
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP----- 618

Query: 117 VPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPC 176
            P A         Q   +       S +  P   A              P  S   + P 
Sbjct: 619 -PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677

Query: 177 GCPLGGEDPPGTPAATPRA-ACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPG 235
             P     PP +P+ATP + A      P    PP+PPA  P    A      P    AP 
Sbjct: 678 SPP---ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP- 733

Query: 236 STPLKKPRRNLEQPP 250
             PL+ P      PP
Sbjct: 734 --PLQVPPSPPASPP 746



 Score = 36.6 bits (83), Expect = 0.031
 Identities = 57/229 (24%), Positives = 74/229 (32%), Gaps = 38/229 (16%)

Query: 51  PCPGLYLAGPAGTPAP--------PPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQP 102
           PCP      P  TP P        PP Q P  PA   P   G P PP +  + P  +  P
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAP--PALASPPLQGLPSPPLSPLATPPPQAPP 623

Query: 103 ERS-----SVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEG 157
             +     +    P      P+AT +      Q   A A     +    P     +    
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPSP-----QAPNALAVHLLQAPFSPPPSPPVQAPFS 678

Query: 158 TAGGWGVFPEVSRAARRP---CGCPLGGEDPPGTPAATPRAACCCAP--------QPAED 206
                 V P  +  ++ P      PL  + PP  PA+ P +     P         P   
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPL--QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736

Query: 207 EPPAPPAVCPRKRCAAGVGGGP---AGCP--APGSTPLKKPRRNLEQPP 250
            PP+PPA  P    A      P   A  P   P S P   P   L +PP
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 50/210 (23%), Positives = 65/210 (30%), Gaps = 26/210 (12%)

Query: 58  AGPAGTPA--PPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGD 115
           A P  +P+  PPPQ  P  P A PP     P PPA+    P   P P    +  AP +  
Sbjct: 712 ASPPMSPSATPPPQAPP--PLAAPPL-QVPPSPPASPPMSPSATPPPRVPPLLAAPPL-- 766

Query: 116 EVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRP 175
           +VP +    +        A     A   +  P   A      +  G   F   +     P
Sbjct: 767 QVPPSPPASLP---MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823

Query: 176 CGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAG----- 230
              P     PP  P           P P    P +P    PR+    G     +G     
Sbjct: 824 LATP-----PPQAPPVLAAPLLQVPPSP----PASPTLQAPRRPPTPGPDTSVSGPRLTL 874

Query: 231 --CPAPGSTPLKKPRRNLEQPPSGGEDDDA 258
              P P   P + P   L  P   G    A
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 42/149 (28%), Positives = 49/149 (32%), Gaps = 41/149 (27%)

Query: 56   YLAGPAGTPA--PPPQQQPGEPAAGPPAGW--GEPPP------PAARASWPETEPQPERS 105
            Y +GP G  A  PPP     E AA  PA W  G  PP      P A   WP         
Sbjct: 914  YDSGPEGGAAASPPPD---AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 970

Query: 106  SV-----SDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAARE------ 154
             +     ++ P      P A   G      GG+A A   A +    P+QA   E      
Sbjct: 971  GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 1030

Query: 155  -----------------AEGTAGGWGVFP 166
                             AEG AGG G  P
Sbjct: 1031 QASVVQHLLSRTLLLAAAEGAAGGSGGGP 1059



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 64/253 (25%), Positives = 84/253 (33%), Gaps = 37/253 (14%)

Query: 57   LAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQ--PERSSVSDAPRVG 114
            L  P   P P P      P        G PPPP+   S   + P      SS +  P   
Sbjct: 852  LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE-- 909

Query: 115  DEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARR 174
                   + G     +GG      AA S       AA   A      W   P    A R 
Sbjct: 910  ------ELRGYDSGPEGG------AAASPPPDAELAACHPA-----AWSRGPAPPLAFRG 952

Query: 175  PCGCPLGGEDPPGTPAATPRAACCC-APQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPA 233
              G PL    PP T   +    C     +  E   PAP A+ P    + G  GG A   A
Sbjct: 953  APGAPLPW--PPATGPGSADGLCTIYETEGPESATPAPGALDPGP--SPGTSGGKAAAGA 1008

Query: 234  PGSTPLKKPRR-NLEQPPSGGEDDDAEEMETGNVANLIS--IFGSSFSGLLRKSPGG-GR 289
                  + P++  L + P G        ++   V +L+S  +  ++  G    S GG G 
Sbjct: 1009 GAGASSRSPKQARLGELPLGA-------LQASVVQHLLSRTLLLAAAEGAAGGSGGGPGG 1061

Query: 290  EEEEGEESGPEAA 302
             E  G   G  AA
Sbjct: 1062 AEGGGVTGGARAA 1074



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 6/60 (10%)

Query: 53  PGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWP-ETEPQPERSSVSDAP 111
           P L  A P   P  PP   P  P A PP     P  P A A+ P +  P P  S    AP
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPP-----PQAPPALATPPLQALPSPPASFPGQAP 812



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 43/159 (27%), Positives = 58/159 (36%), Gaps = 21/159 (13%)

Query: 84  GEPPPPAARASWPE-TEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWS 142
           G P P  AR S    TE    R + S  PR   E P  +V+   +      + A     S
Sbjct: 170 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229

Query: 143 RVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQ 202
              G ++ A+R    +A        +S  AR        G    GTP A    +    P+
Sbjct: 230 AGGGLQRPASRSLSSSA------TPLSSPAR-------SGPSARGTPRAPAHPS---QPK 273

Query: 203 PAEDEPPAPPAVCP-RKRCAAGVG---GGPAGCPAPGST 237
           P   +   PP V P RK  A  +G     P   P+P  T
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT 312


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/83 (37%), Positives = 39/83 (46%), Gaps = 8/83 (9%)

Query: 44  RQVYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWG--EPPPPAAR-----ASWP 96
           R + LS   P L   G +G   PPP ++P  P   PP   G   PPPP +R      + P
Sbjct: 337 RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396

Query: 97  ETEPQPERSSVSDAPRVGDEVPV 119
            T   P RS V D+PR G   P+
Sbjct: 397 ATPQLPSRSGV-DSPRSGPRPPL 418



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 7/153 (4%)

Query: 64  PAPPPQQ-QPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATV 122
           P PPPQ  +P  P+   P+   + PPP    S P   P P  SS +D      +  ++  
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342

Query: 123 TGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGG 182
           +    +   G +       S    P     R+  G +G     P VSR        P   
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPP---PVRDPPGRSGPLPPPPPVSRNGSTSRALPATP 399

Query: 183 EDPPGTPAATPRAA---CCCAPQPAEDEPPAPP 212
           + P  +   +PR+         +P+   PP PP
Sbjct: 400 QLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 54/227 (23%), Positives = 75/227 (33%), Gaps = 48/227 (21%)

Query: 58  AGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSS---VSDAPRVG 114
           +GP   P P P  + G P    P     PPP     S P++ P P  S+   +  +P   
Sbjct: 145 SGPGRFPVPSPGHRSGPPE---PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNR 201

Query: 115 DEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEV-----S 169
              PV           GG    +        GP         GTA G G   +      S
Sbjct: 202 GSPPVP----------GGPRQPSP-------GPTPPPFPGNRGTALGGGSIRQSPLSSSS 244

Query: 170 RAARRPCGCP-----LGGEDPPGTPAATPRAA----CCCAPQPAEDEPPAPPAVCPRKRC 220
             + RP   P     L  + PP  P    R +        P P  ++PP P    PR   
Sbjct: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST--PRPSA 302

Query: 221 AAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVA 267
           ++     P     PG  PL         PPS   +D+   +   N++
Sbjct: 303 SSQAPPPPPPPSRPGPPPL---------PPSSSGNDETPRLPQRNLS 340



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 48/188 (25%), Positives = 59/188 (31%), Gaps = 51/188 (27%)

Query: 58  AGPAGTPAPPPQQQPGEPAAGPPAGWGE-----------------PPPPAARASWPETEP 100
           A     P PPP  +PG P   PP+  G                  PP P+   S P   P
Sbjct: 302 ASSQAPPPPPPPSRPGPPPL-PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360

Query: 101 QPER--SSVSDAP-RVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEG 157
             ER    V D P R G   P   V+  G   +   A     + S V+ PR         
Sbjct: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS-------- 412

Query: 158 TAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAP-----------QPAED 206
                G  P +      P   P  G  PP  P+ + R     +P            P  D
Sbjct: 413 -----GPRPPL------PPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISD 461

Query: 207 EPPAPPAV 214
            PP  P V
Sbjct: 462 LPPPEPYV 469


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/83 (37%), Positives = 39/83 (46%), Gaps = 8/83 (9%)

Query: 44  RQVYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWG--EPPPPAAR-----ASWP 96
           R + LS   P L   G +G   PPP ++P  P   PP   G   PPPP +R      + P
Sbjct: 337 RNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396

Query: 97  ETEPQPERSSVSDAPRVGDEVPV 119
            T   P RS V D+PR G   P+
Sbjct: 397 ATPQLPSRSGV-DSPRSGPRPPL 418



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 7/153 (4%)

Query: 64  PAPPPQQ-QPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATV 122
           P PPPQ  +P  P+   P+   + PPP    S P   P P  SS +D      +  ++  
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342

Query: 123 TGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGG 182
           +    +   G +       S    P     R+  G +G     P VSR        P   
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPP---PVRDPPGRSGPLPPPPPVSRNGSTSRALPATP 399

Query: 183 EDPPGTPAATPRAA---CCCAPQPAEDEPPAPP 212
           + P  +   +PR+         +P+   PP PP
Sbjct: 400 QLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 54/227 (23%), Positives = 75/227 (33%), Gaps = 48/227 (21%)

Query: 58  AGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSS---VSDAPRVG 114
           +GP   P P P  + G P    P     PPP     S P++ P P  S+   +  +P   
Sbjct: 145 SGPGRFPVPSPGHRSGPPE---PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNR 201

Query: 115 DEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEV-----S 169
              PV           GG    +        GP         GTA G G   +      S
Sbjct: 202 GSPPVP----------GGPRQPSP-------GPTPPPFPGNRGTALGGGSIRQSPLSSSS 244

Query: 170 RAARRPCGCP-----LGGEDPPGTPAATPRAA----CCCAPQPAEDEPPAPPAVCPRKRC 220
             + RP   P     L  + PP  P    R +        P P  ++PP P    PR   
Sbjct: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST--PRPSA 302

Query: 221 AAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVA 267
           ++     P     PG  PL         PPS   +D+   +   N++
Sbjct: 303 SSQAPPPPPPPSRPGPPPL---------PPSSSGNDETPRLPQRNLS 340



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 48/188 (25%), Positives = 59/188 (31%), Gaps = 51/188 (27%)

Query: 58  AGPAGTPAPPPQQQPGEPAAGPPAGWGE-----------------PPPPAARASWPETEP 100
           A     P PPP  +PG P   PP+  G                  PP P+   S P   P
Sbjct: 302 ASSQAPPPPPPPSRPGPPPL-PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360

Query: 101 QPER--SSVSDAP-RVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEG 157
             ER    V D P R G   P   V+  G   +   A     + S V+ PR         
Sbjct: 361 PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS-------- 412

Query: 158 TAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAP-----------QPAED 206
                G  P +      P   P  G  PP  P+ + R     +P            P  D
Sbjct: 413 -----GPRPPL------PPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISD 461

Query: 207 EPPAPPAV 214
            PP  P V
Sbjct: 462 LPPPEPYV 469


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 69/228 (30%), Positives = 81/228 (35%), Gaps = 39/228 (17%)

Query: 53   PGLYLAGPAGT------PA-PPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPER- 104
            PG+   G   T      PA PP Q     PA   P   GEP    A  +  E E  PE  
Sbjct: 2171 PGVINGGDVSTVVAEEPPALPPDQASTRLPAELEPEPSGEPKLDVALEAAVEAETVPEER 2230

Query: 105  ------SSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAA-WSRVEGPRQAAAREAEG 157
                  SSV  AP   ++ P+    G GD  QG EA+   AA     +GP      +A+ 
Sbjct: 2231 ARGDPDSSVEPAPVPPEQRPL----GSGD--QGAEAEGPPAASLCAPDGPAPNTVAQAQA 2284

Query: 158  TAG-GWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAP----- 211
              G G     E SRAA          E PPG     P AA    P+P  + P AP     
Sbjct: 2285 ADGAGPEDDTEASRAA-------APAEGPPG--GIQPEAA---EPKPTAEAPKAPRVEEI 2332

Query: 212  PAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAE 259
            P    R R          G P         P         G EDDDA+
Sbjct: 2333 PQRMTRNRAQMLANQSKQGPPPSEKECAPTPAPVTRAKARGSEDDDAQ 2380


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 48  LSDPCPGLYLAGPAGTPAPP-PQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSS 106
           LS P PG  +  P   P PP P  QPG+P++ P +     P P+  +  P   PQP +S 
Sbjct: 433 LSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP 492

Query: 107 VS 108
           V+
Sbjct: 493 VT 494


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 48  LSDPCPGLYLAGPAGTPAPP-PQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSS 106
           LS P PG  +  P   P PP P  QPG+P++ P +     P P+  +  P   PQP +S 
Sbjct: 393 LSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP 452

Query: 107 VS 108
           V+
Sbjct: 453 VT 454


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 60/228 (26%), Positives = 77/228 (33%), Gaps = 50/228 (21%)

Query: 51  PCPGLYLAG------PAGTPA---PPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQ 101
           P PG    G      PAG PA   PPPQ  P +P  GP     + PP   R       PQ
Sbjct: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQR---QGPPLQQR-----PPPQ 488

Query: 102 PERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGG 161
            ++      P  G  +P    +            A +   S+   P Q   R++   AGG
Sbjct: 489 GQQHLSGLGPPAGSPLPQRLPS---------PTSAPQQPASQAAPPTQGQGRQSRPVAGG 539

Query: 162 WG----VFPEVSRAARRPCGCP-------LGGEDPPGTPAATPRAACCCAPQPAEDEPPA 210
            G      P  S + +R  G P       + G  PP    A P        Q  +  P  
Sbjct: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP------GGQQRQGPPQK 593

Query: 211 PPAVCPRKRCAAGVGGGPAGCP-------APGSTPLKKPRRNLEQPPS 251
           PP      R A+  G  P   P         G  P  +P+  L Q PS
Sbjct: 594 PPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPS 641



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 27/202 (13%)

Query: 51  PCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEP---PPPAARASWPETEPQPERSSV 107
           P PG    GP     PPPQ Q      GPPAG   P   P P +    P ++  P     
Sbjct: 470 PGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529

Query: 108 SDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPE 167
               R     PVA   G     +   + + +    R  GP QA  + +            
Sbjct: 530 GRQSR-----PVAGGPGAPPAARPPASPSPQ----RQAGPPQATRQTSVS---------- 570

Query: 168 VSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGG 227
              A  +  G P GG+   G P   P  A     + A    P P    P  +     G G
Sbjct: 571 -GPAPPKASGAPPGGQQRQGPPQKPPGPA--GPTRQASQAGPVPRTGPPTTQQPRPSGPG 627

Query: 228 PAGCPAPGSTPLKKPRRNLEQP 249
           PAG P P     +KP +++  P
Sbjct: 628 PAGRPKPQLA--QKPSQDVPPP 647



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 27/78 (34%), Positives = 32/78 (41%), Gaps = 12/78 (15%)

Query: 59  GPAGTPAPPPQQQPGEPAAGP-PAGWGEPPPPAARASWPET------EPQPERSSVSDAP 111
           GPAG P P   Q+P +    P  A  G PP P    S   T      EP P R S+S   
Sbjct: 627 GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQ-- 684

Query: 112 RVGDEVPVATVTGVGDVF 129
              DEV   T+  +   F
Sbjct: 685 ---DEVKAETIRSLRKSF 699



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 57/252 (22%), Positives = 78/252 (30%), Gaps = 61/252 (24%)

Query: 32  KNLLVSLVLRSARQVY----LSDPCPGLYLAGPAGTP-APPPQQQPGEPAAGPPAGWGEP 86
           K L+V LV+    Q        D  PG    G   +P A P  +Q  +  AGPPA   + 
Sbjct: 403 KQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ--QR 460

Query: 87  PPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEG 146
           PPP  +   P+  P P+R                                        +G
Sbjct: 461 PPP--QGGPPQPGPGPQR----------------------------------------QG 478

Query: 147 PRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAED 206
           P        +G     G+ P       +    P      P + AA P        +P   
Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAG 538

Query: 207 EPPAPPA----VCPRKRCAAGVG--------GGPAGCPAPGSTPLKKPRRNLEQPPSGGE 254
            P APPA      P  +  AG           GPA   A G+ P  + R+   Q P G  
Sbjct: 539 GPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPA 598

Query: 255 DDDAEEMETGNV 266
               +  + G V
Sbjct: 599 GPTRQASQAGPV 610



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 12/77 (15%)

Query: 41  RSARQVYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARA-----SW 95
           ++ RQ  +S P P      P  + APP  QQ   P   PP   G P   A++A     + 
Sbjct: 562 QATRQTSVSGPAP------PKASGAPPGGQQRQGPPQKPPGPAG-PTRQASQAGPVPRTG 614

Query: 96  PETEPQPERSSVSDAPR 112
           P T  QP  S    A R
Sbjct: 615 PPTTQQPRPSGPGPAGR 631


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 60/228 (26%), Positives = 77/228 (33%), Gaps = 50/228 (21%)

Query: 51  PCPGLYLAG------PAGTPA---PPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQ 101
           P PG    G      PAG PA   PPPQ  P +P  GP     + PP   R       PQ
Sbjct: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQR---QGPPLQQR-----PPPQ 488

Query: 102 PERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGG 161
            ++      P  G  +P    +            A +   S+   P Q   R++   AGG
Sbjct: 489 GQQHLSGLGPPAGSPLPQRLPS---------PTSAPQQPASQAAPPTQGQGRQSRPVAGG 539

Query: 162 WG----VFPEVSRAARRPCGCP-------LGGEDPPGTPAATPRAACCCAPQPAEDEPPA 210
            G      P  S + +R  G P       + G  PP    A P        Q  +  P  
Sbjct: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP------GGQQRQGPPQK 593

Query: 211 PPAVCPRKRCAAGVGGGPAGCP-------APGSTPLKKPRRNLEQPPS 251
           PP      R A+  G  P   P         G  P  +P+  L Q PS
Sbjct: 594 PPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPS 641



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 27/202 (13%)

Query: 51  PCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEP---PPPAARASWPETEPQPERSSV 107
           P PG    GP     PPPQ Q      GPPAG   P   P P +    P ++  P     
Sbjct: 470 PGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529

Query: 108 SDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPE 167
               R     PVA   G     +   + + +    R  GP QA  + +            
Sbjct: 530 GRQSR-----PVAGGPGAPPAARPPASPSPQ----RQAGPPQATRQTSVS---------- 570

Query: 168 VSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGG 227
              A  +  G P GG+   G P   P  A     + A    P P    P  +     G G
Sbjct: 571 -GPAPPKASGAPPGGQQRQGPPQKPPGPA--GPTRQASQAGPVPRTGPPTTQQPRPSGPG 627

Query: 228 PAGCPAPGSTPLKKPRRNLEQP 249
           PAG P P     +KP +++  P
Sbjct: 628 PAGRPKPQLA--QKPSQDVPPP 647



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 57/252 (22%), Positives = 78/252 (30%), Gaps = 61/252 (24%)

Query: 32  KNLLVSLVLRSARQVY----LSDPCPGLYLAGPAGTP-APPPQQQPGEPAAGPPAGWGEP 86
           K L+V LV+    Q        D  PG    G   +P A P  +Q  +  AGPPA   + 
Sbjct: 403 KQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ--QR 460

Query: 87  PPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEG 146
           PPP  +   P+  P P+R                                        +G
Sbjct: 461 PPP--QGGPPQPGPGPQR----------------------------------------QG 478

Query: 147 PRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAED 206
           P        +G     G+ P       +    P      P + AA P        +P   
Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAG 538

Query: 207 EPPAPPA----VCPRKRCAAGVG--------GGPAGCPAPGSTPLKKPRRNLEQPPSGGE 254
            P APPA      P  +  AG           GPA   A G+ P  + R+   Q P G  
Sbjct: 539 GPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPA 598

Query: 255 DDDAEEMETGNV 266
               +  + G V
Sbjct: 599 GPTRQASQAGPV 610



 Score = 32.7 bits (73), Expect = 0.45
 Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)

Query: 59  GPAGTPAPPPQQQPGEPAAGP-PAGWGEPPPPAARASWPETEP 100
           GPAG P P   Q+P +    P  A  G PP P  +AS  + +P
Sbjct: 627 GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 12/77 (15%)

Query: 41  RSARQVYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARA-----SW 95
           ++ RQ  +S P P      P  + APP  QQ   P   PP   G P   A++A     + 
Sbjct: 562 QATRQTSVSGPAP------PKASGAPPGGQQRQGPPQKPPGPAG-PTRQASQAGPVPRTG 614

Query: 96  PETEPQPERSSVSDAPR 112
           P T  QP  S    A R
Sbjct: 615 PPTTQQPRPSGPGPAGR 631


>gi|154759423 Cdk5 and Abl enzyme substrate 1 isoform 2 [Homo
           sapiens]
          Length = 633

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 60/205 (29%), Positives = 78/205 (38%), Gaps = 48/205 (23%)

Query: 54  GLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRV 113
           G   AG +G   PPPQ QP +PAA  PA   +PPP   R   P  +P+  ++++S    +
Sbjct: 19  GTDAAGASGLQQPPPQPQP-QPAAAAPA---QPPPEPPRK--PRMDPRRRQAALSFLTNI 72

Query: 114 GDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAAR 173
             +               G     +A W    G    AA+   G A G      +  AA 
Sbjct: 73  SLD---------------GRLPPQDAEWG--GGEEGGAAKPGAGGACGARTRFSLLAAAE 115

Query: 174 RPCGCPLGGEDPPGTPAATPRAAC-CCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCP 232
           R     L     PGTPAA   A    C PQP+   P  P              GG A   
Sbjct: 116 RGGCIALAA---PGTPAAGLAAGSGPCLPQPSSLPPLIP--------------GGHATVS 158

Query: 233 APG-----STPLKKPRRNLE--QPP 250
            PG     ++PL   R + E  QPP
Sbjct: 159 GPGVARGFASPLGAGRASGEQWQPP 183


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 87/334 (26%), Positives = 104/334 (31%), Gaps = 103/334 (30%)

Query: 50  DPCPGLYLAGPAGTPAPP------------------PQQQPGEPAAGPPAG--WG---EP 86
           DP P      P GT  PP                  PQ  P  PA GPP G  W      
Sbjct: 641 DPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLA 700

Query: 87  PPPAARASWPETEPQPERSSVS---DAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSR 143
            PPA     P   P+P+R S S     P  GD                            
Sbjct: 701 GPPAT----PPDPPRPKRRSHSLSRPGPTEGD---------------------------- 728

Query: 144 VEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPA---ATPRAACCCA 200
                  A  EAEG  G        +   RRP    L    P  TP     TPR+     
Sbjct: 729 -------AEGEAEGPVG--STLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFAL 779

Query: 201 PQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKK----PRRNLEQPPSG---- 252
               +  PP PP     KR ++  G  P   P   S   K+    PRR     P+G    
Sbjct: 780 RARRKGPPPPPP-----KRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEP 834

Query: 253 -------GEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAE-- 303
                  G   D EE E G      S  GSS  GL     G    ++  + +GP   E  
Sbjct: 835 PGPPAPAGPASDTEEEEPGPEGTPPS-RGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETP 893

Query: 304 --PG--------QICCDKPVLRDMNPWSTAIVAF 327
             PG             +P  R+  P  TA++AF
Sbjct: 894 VPPGLDFNLTESDTVKRRPKCREREPLQTALLAF 927



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 20/72 (27%), Positives = 26/72 (36%)

Query: 67  PPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVG 126
           P  + P  P    P     P PPA     P T  Q  R  +S     GD   V +   VG
Sbjct: 270 PAARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVG 329

Query: 127 DVFQGGEADATE 138
            +   G   ++E
Sbjct: 330 SIRSAGSGQSSE 341



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 34/118 (28%), Positives = 45/118 (38%), Gaps = 19/118 (16%)

Query: 60   PAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPE-----TEPQPERSSVSD----- 109
            PA  P  PP   PG  ++      GE  PPAA A+  +     T P+P   + +      
Sbjct: 975  PAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSG 1034

Query: 110  ---APRVGDE-VPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAA-----AREAEGT 158
               APR+G   VP       G V  G      E   S +    +AA      +E EGT
Sbjct: 1035 PKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGT 1092



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 43/166 (25%), Positives = 63/166 (37%), Gaps = 23/166 (13%)

Query: 51   PCPGLYLAGPAGTPAPPPQQQP-GEPAAGPPAGWGEP--PPPAARASWPETEPQPERSSV 107
            P P   L  P    +PP    P  EP++ P  G   P  P PA +   P   P P   S 
Sbjct: 934  PGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPC-PGPGLESS 992

Query: 108  SDAPRVGDEVPVAT------VTGVGDVFQGGEADATEAAWSRVE-----GPRQA--AARE 154
            + +   G+  P A       V G G   +      T+ A+S  +     GPR       E
Sbjct: 993  AASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPE 1052

Query: 155  AEGTAGGWGVFPEVSR------AARRPCGCPLGGEDPPGTPAATPR 194
            + GT G       + +      AA R     +G ++  GTP+A+ +
Sbjct: 1053 STGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTK 1098


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 87/334 (26%), Positives = 104/334 (31%), Gaps = 103/334 (30%)

Query: 50   DPCPGLYLAGPAGTPAPP------------------PQQQPGEPAAGPPAG--WG---EP 86
            DP P      P GT  PP                  PQ  P  PA GPP G  W      
Sbjct: 723  DPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLA 782

Query: 87   PPPAARASWPETEPQPERSSVS---DAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSR 143
             PPA     P   P+P+R S S     P  GD                            
Sbjct: 783  GPPAT----PPDPPRPKRRSHSLSRPGPTEGD---------------------------- 810

Query: 144  VEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPA---ATPRAACCCA 200
                   A  EAEG  G        +   RRP    L    P  TP     TPR+     
Sbjct: 811  -------AEGEAEGPVG--STLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFAL 861

Query: 201  PQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKK----PRRNLEQPPSG---- 252
                +  PP PP     KR ++  G  P   P   S   K+    PRR     P+G    
Sbjct: 862  RARRKGPPPPPP-----KRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEP 916

Query: 253  -------GEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAE-- 303
                   G   D EE E G      S  GSS  GL     G    ++  + +GP   E  
Sbjct: 917  PGPPAPAGPASDTEEEEPGPEGTPPS-RGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETP 975

Query: 304  --PG--------QICCDKPVLRDMNPWSTAIVAF 327
              PG             +P  R+  P  TA++AF
Sbjct: 976  VPPGLDFNLTESDTVKRRPKCREREPLQTALLAF 1009



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 20/72 (27%), Positives = 26/72 (36%)

Query: 67  PPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVG 126
           P  + P  P    P     P PPA     P T  Q  R  +S     GD   V +   VG
Sbjct: 352 PAARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVG 411

Query: 127 DVFQGGEADATE 138
            +   G   ++E
Sbjct: 412 SIRSAGSGQSSE 423



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 34/118 (28%), Positives = 45/118 (38%), Gaps = 19/118 (16%)

Query: 60   PAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPE-----TEPQPERSSVSD----- 109
            PA  P  PP   PG  ++      GE  PPAA A+  +     T P+P   + +      
Sbjct: 1057 PAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSG 1116

Query: 110  ---APRVGDE-VPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAA-----AREAEGT 158
               APR+G   VP       G V  G      E   S +    +AA      +E EGT
Sbjct: 1117 PKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGT 1174



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 43/166 (25%), Positives = 63/166 (37%), Gaps = 23/166 (13%)

Query: 51   PCPGLYLAGPAGTPAPPPQQQP-GEPAAGPPAGWGEP--PPPAARASWPETEPQPERSSV 107
            P P   L  P    +PP    P  EP++ P  G   P  P PA +   P   P P   S 
Sbjct: 1016 PGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPC-PGPGLESS 1074

Query: 108  SDAPRVGDEVPVAT------VTGVGDVFQGGEADATEAAWSRVE-----GPRQA--AARE 154
            + +   G+  P A       V G G   +      T+ A+S  +     GPR       E
Sbjct: 1075 AASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPE 1134

Query: 155  AEGTAGGWGVFPEVSR------AARRPCGCPLGGEDPPGTPAATPR 194
            + GT G       + +      AA R     +G ++  GTP+A+ +
Sbjct: 1135 STGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTK 1180


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 65/250 (26%), Positives = 87/250 (34%), Gaps = 52/250 (20%)

Query: 60  PAGTPAPPPQQQPGEPAAGPPAGWGEPPPP-----AARASWPETEPQPERSSVSDAPRVG 114
           P G P  PP Q   +P   PP G  + PPP     +  A  P  +PQ       + P+ G
Sbjct: 197 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ-G 255

Query: 115 DEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARR 174
              P     G     QGG         ++ +GP      +     GG       SR++R 
Sbjct: 256 PPPPPGKPQGPPP--QGG---------NKPQGPPPPGKPQGPPPQGG-----SKSRSSRS 299

Query: 175 PCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAP 234
           P G P G   PP      P+      P P   +P  PP   P+       G  P G P P
Sbjct: 300 PPGKPQG---PPPQGGNQPQG-----PPPPPGKPQGPP---PQG------GNKPQGPPPP 342

Query: 235 GSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEG 294
           G     KP+     PP GG    +     G         G++  G     P GG  +   
Sbjct: 343 G-----KPQ---GPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQG--PPPPAGGNPQ--- 389

Query: 295 EESGPEAAEP 304
           +   P A +P
Sbjct: 390 QPQAPPAGQP 399



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 64/269 (23%), Positives = 86/269 (31%), Gaps = 40/269 (14%)

Query: 60  PAGTPAPPPQQ----------QPGEPAAGPPAGWGEP--PPPAARASWPETEPQPERSSV 107
           P G P  PP Q           PG+P   PP G  +P  PPP  +   P     P +   
Sbjct: 53  PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-----PPQGDK 107

Query: 108 SDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEG---TAGGWGV 164
           S +PR     P       G+  QG           + +GP      + +G        G 
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPP-----GKPQGPPPQGGNKPQGPPPPGKPQGP 162

Query: 165 FPE---VSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCA 221
            P+    SR++R P G P G   PP      P+      P P   +P  PP     K   
Sbjct: 163 PPQGDNKSRSSRSPPGKPQG---PPPQGGNQPQ-----GPPPPPGKPQGPPPQGGNKPQG 214

Query: 222 AGVGGGPAGCPAPGSTPLKK----PRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSF 277
               G P G P  G    +     P +    PP GG          G         G+  
Sbjct: 215 PPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 274

Query: 278 SGLLRKSPGGGREEEEGEESGPEAAEPGQ 306
            G        G   + G +S    + PG+
Sbjct: 275 QGPPPPGKPQGPPPQGGSKSRSSRSPPGK 303



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 50/179 (27%), Positives = 65/179 (36%), Gaps = 28/179 (15%)

Query: 60  PAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEV-- 117
           P G P  PP Q   +P   PP G  + PPP    S   +   P        P+ G++   
Sbjct: 259 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-GSKSRSSRSPPGKPQGPPPQGGNQPQG 317

Query: 118 -PVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPC 176
            P       G   QGG         ++ +GP      +     GG       SR+AR P 
Sbjct: 318 PPPPPGKPQGPPPQGG---------NKPQGPPPPGKPQGPPPQGG-----SKSRSARSPP 363

Query: 177 GCPLGGEDPPGTPAATPRAACCCAPQPA---EDEPPAPPAVCPRKRCAAGVGGGPAGCP 232
           G P G   PP      P+      P PA     +P APPA  P+       GG P+  P
Sbjct: 364 GKPQG---PPQQEGNNPQG----PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 38/148 (25%), Positives = 53/148 (35%), Gaps = 23/148 (15%)

Query: 60  PAGTPAPPPQQ----------QPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSD 109
           P G P  PP Q           PG+P   PP G  +P  P      P+  P    +    
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 338

Query: 110 APRVGDEVPVATVTGVGDVFQGG-EADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEV 168
            P  G           G   QGG ++ +  +   + +GP Q      +G     G  P+ 
Sbjct: 339 PPPPGKP--------QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 390

Query: 169 SRAARRPCGCPLGGEDPP--GTPAATPR 194
            +A   P G P G   PP  G P+  P+
Sbjct: 391 PQAP--PAGQPQGPPRPPQGGRPSRPPQ 416


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 53/204 (25%), Positives = 62/204 (30%), Gaps = 36/204 (17%)

Query: 46  VYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERS 105
           VY      G+    P G   PPP    G+P   PP   G  PP   +   P   P P  S
Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQP---PPPPSGPLPPWQQQQQQPPPPPPPSSS 516

Query: 106 SVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVF 165
             S  P    +    T T  G          +   W +    +QAAA  + G     G  
Sbjct: 517 MASSTPLPWQQNTTTTTTSAG--------TGSIPPWQQ----QQAAAAASPGAPQMQG-- 562

Query: 166 PEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDE-------PPAPPAVCPRK 218
                    P   PL    PPG     P  A    P P           PP PP      
Sbjct: 563 --------NPTMVPL----PPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPS 610

Query: 219 RCAAGVGGGPAGCPAPGSTPLKKP 242
                +G G AG P  G  P   P
Sbjct: 611 NFVTMMGMGVAGMPPFGMPPAPPP 634



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 19/55 (34%), Positives = 22/55 (40%), Gaps = 14/55 (25%)

Query: 49  SDPCPGLYLAGPAGTPAPP---PQQQP-------GEPAA----GPPAGWGEPPPP 89
           S P  G++  GP G    P   P   P       G P      GPP  W +PPPP
Sbjct: 376 SRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP 430


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.134    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,168,076
Number of Sequences: 37866
Number of extensions: 1406566
Number of successful extensions: 19551
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 374
Number of HSP's successfully gapped in prelim test: 1313
Number of HSP's that attempted gapping in prelim test: 10234
Number of HSP's gapped (non-prelim): 7260
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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