Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 9955968
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9955968 ATP-binding cassette, sub-family B (MDR/TAP), member
9 isoform 2 [Homo sapiens]
(723 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9955968 ATP-binding cassette, sub-family B (MDR/TAP), member ... 1420 0.0
gi|9955966 ATP-binding cassette, sub-family B (MDR/TAP), member ... 1399 0.0
gi|45243524 ATP-binding cassette, sub-family B (MDR/TAP), member... 1399 0.0
gi|73747915 transporter 2, ATP-binding cassette, sub-family B is... 444 e-124
gi|73747917 transporter 2, ATP-binding cassette, sub-family B is... 412 e-115
gi|9665248 transporter 1, ATP-binding cassette, sub-family B [Ho... 409 e-114
gi|171184400 ATP-binding cassette, sub-family B, member 10 [Homo... 361 1e-99
gi|156105685 ATP-binding cassette, sub-family B, member 8 [Homo ... 333 3e-91
gi|21536378 ATP-binding cassette, sub-family B (MDR/TAP), member... 302 8e-82
gi|9961252 ATP-binding cassette, subfamily B, member 4 isoform C... 298 9e-81
gi|42741659 ATP-binding cassette, subfamily B, member 1 [Homo sa... 296 3e-80
gi|9961250 ATP-binding cassette, subfamily B, member 4 isoform B... 295 1e-79
gi|4505771 ATP-binding cassette, subfamily B, member 4 isoform A... 295 1e-79
gi|148612844 ATP-binding cassette, sub-family B, member 5 [Homo ... 265 9e-71
gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo sa... 219 9e-57
gi|42490749 ATP-binding cassette, sub-family B, member 7 [Homo s... 189 8e-48
gi|4557481 ATP-binding cassette, sub-family C (CFTR/MRP), member... 152 1e-36
gi|66529005 ATP-binding cassette, sub-family C, member 5 isoform... 150 3e-36
gi|134142345 ATP-binding cassette, sub-family C, member 1 isofor... 145 1e-34
gi|134142342 ATP-binding cassette, sub-family C, member 1 isofor... 145 1e-34
gi|134142340 ATP-binding cassette, sub-family C, member 1 isofor... 145 1e-34
gi|134142337 ATP-binding cassette, sub-family C, member 1 isofor... 145 1e-34
gi|25914749 ATP-binding cassette, sub-family C, member 10 [Homo ... 144 4e-34
gi|110832837 ATP-binding cassette, sub-family C, member 9 isofor... 140 4e-33
gi|239756495 PREDICTED: hypothetical protein [Homo sapiens] 135 1e-31
gi|190343023 ATP-binding cassette, sub-family C, member 6 isofor... 135 2e-31
gi|110832839 ATP-binding cassette, sub-family C, member 9 isofor... 134 3e-31
gi|110832835 ATP-binding cassette, sub-family C, member 9 isofor... 134 3e-31
gi|157502201 ATP-binding cassette, sub-family C, member 4 isofor... 134 4e-31
gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform ... 131 2e-30
>gi|9955968 ATP-binding cassette, sub-family B (MDR/TAP), member 9
isoform 2 [Homo sapiens]
Length = 723
Score = 1420 bits (3675), Expect = 0.0
Identities = 723/723 (100%), Positives = 723/723 (100%)
Query: 1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 60
MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL
Sbjct: 1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 60
Query: 61 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 120
LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF
Sbjct: 61 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 120
Query: 121 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 180
VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY
Sbjct: 121 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 180
Query: 181 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 240
TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS
Sbjct: 181 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 240
Query: 241 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 300
FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV
Sbjct: 241 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 300
Query: 301 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 360
SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA
Sbjct: 301 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 360
Query: 361 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGSVG 420
LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGSVG
Sbjct: 361 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGSVG 420
Query: 421 SVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQ 480
SVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQ
Sbjct: 421 SVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQ 480
Query: 481 NVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVIS 540
NVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVIS
Sbjct: 481 NVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVIS 540
Query: 541 LVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQL 600
LVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQL
Sbjct: 541 LVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQL 600
Query: 601 SGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLST 660
SGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLST
Sbjct: 601 SGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLST 660
Query: 661 VEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGS 720
VEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGS
Sbjct: 661 VEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGS 720
Query: 721 HKA 723
HKA
Sbjct: 721 HKA 723
>gi|9955966 ATP-binding cassette, sub-family B (MDR/TAP), member 9
isoform 1 [Homo sapiens]
Length = 766
Score = 1399 bits (3621), Expect = 0.0
Identities = 723/766 (94%), Positives = 723/766 (94%), Gaps = 43/766 (5%)
Query: 1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 60
MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL
Sbjct: 1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 60
Query: 61 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 120
LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF
Sbjct: 61 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 120
Query: 121 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 180
VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY
Sbjct: 121 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 180
Query: 181 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 240
TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS
Sbjct: 181 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 240
Query: 241 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 300
FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV
Sbjct: 241 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 300
Query: 301 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 360
SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA
Sbjct: 301 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 360
Query: 361 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSG--- 417
LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSG
Sbjct: 361 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 420
Query: 418 ----------------------------------------SVGSVYSGLMQGVGAAEKVF 437
SVGSVYSGLMQGVGAAEKVF
Sbjct: 421 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF 480
Query: 438 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 497
EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP
Sbjct: 481 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 540
Query: 498 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 557
SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI
Sbjct: 541 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 600
Query: 558 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 617
SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN
Sbjct: 601 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 660
Query: 618 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 677
PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ
Sbjct: 661 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 720
Query: 678 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 723
QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA
Sbjct: 721 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 766
>gi|45243524 ATP-binding cassette, sub-family B (MDR/TAP), member 9
isoform 1 [Homo sapiens]
Length = 766
Score = 1399 bits (3621), Expect = 0.0
Identities = 723/766 (94%), Positives = 723/766 (94%), Gaps = 43/766 (5%)
Query: 1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 60
MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL
Sbjct: 1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 60
Query: 61 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 120
LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF
Sbjct: 61 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 120
Query: 121 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 180
VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY
Sbjct: 121 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 180
Query: 181 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 240
TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS
Sbjct: 181 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 240
Query: 241 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 300
FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV
Sbjct: 241 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 300
Query: 301 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 360
SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA
Sbjct: 301 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 360
Query: 361 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSG--- 417
LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSG
Sbjct: 361 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 420
Query: 418 ----------------------------------------SVGSVYSGLMQGVGAAEKVF 437
SVGSVYSGLMQGVGAAEKVF
Sbjct: 421 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF 480
Query: 438 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 497
EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP
Sbjct: 481 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 540
Query: 498 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 557
SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI
Sbjct: 541 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 600
Query: 558 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 617
SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN
Sbjct: 601 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 660
Query: 618 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 677
PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ
Sbjct: 661 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 720
Query: 678 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 723
QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA
Sbjct: 721 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 766
>gi|73747915 transporter 2, ATP-binding cassette, sub-family B
isoform 1 [Homo sapiens]
Length = 703
Score = 444 bits (1143), Expect = e-124
Identities = 262/660 (39%), Positives = 384/660 (58%), Gaps = 74/660 (11%)
Query: 89 VCLFVGIYAMVKLLLFSEVRRP----IRDPWFWALFVWTYISLGASFLLWWLLSTVRPGT 144
+CL + ++ L+ R P PW W L + GA+ L W L + + P
Sbjct: 69 LCLATPLTVSLRALVAGASRAPPARVASAPWSWLL-----VGYGAAGLSWSLWAVLSP-- 121
Query: 145 QALEPGAATEAEGFPGSGRPPPEQASGATLQ-KLLSYTKPDVAFLVAASFFLIVAALGET 203
PG+ +Q + L +LL ++PD+ LVAA FFL++A LGET
Sbjct: 122 --------------PGAQEKEQDQVNNKVLMWRLLKLSRPDLPLLVAAFFFLVLAVLGET 167
Query: 204 FLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRN 263
+P+Y+GR ID + F++A+ +CL + GSS +AG RGG FT +R+N+R+R
Sbjct: 168 LIPHYSGRVIDILGGDFDPHAFASAIFFMCLFSFGSSLSAGCRGGCFTYTMSRINLRIRE 227
Query: 264 CLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFS 323
LF SL+ Q+ FF E +TG+L SRL+SDTT++S+ + N NV LR+ VKV G+ FM S
Sbjct: 228 QLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLS 287
Query: 324 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFAN 383
+S +L+L++ + P + +Y ++ + +E+Q+A+ARA E + ++TVRSF
Sbjct: 288 ISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGA 347
Query: 384 EEEEAEVY---LRKLQQVYKLNRKEAAAYMY----------------------------- 411
EE E Y L + +Q+Y E A Y+
Sbjct: 348 EEHEVCRYKEALEQCRQLYWRRDLERALYLLVRRVLHLGVQMLMLSCGLQQMQDGELTQG 407
Query: 412 ----YVWGSGSVGS-------VYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGR 460
++ SVGS +Y ++ VGAAEKVF ++DRQP + G+LAP L+G
Sbjct: 408 SLLSFMIYQESVGSYVQTLVYIYGDMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGV 467
Query: 461 VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRV 520
V F++V+F Y RP VL+ ++F+L PG+VTALVGP+GSGKS+ +L+N Y GG+V
Sbjct: 468 VKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Query: 521 LLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHG 580
LLD KPIS Y+H YLH + V QEPVLF+ S+ +NI+YGL + + V+ AAQ A+A
Sbjct: 528 LLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADD 587
Query: 581 FIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQ 640
FI E++ G T+ GEKG+QL+ GQKQR+A+ARALVR+P VLILDEATSALD + E +Q
Sbjct: 588 FIQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 641 AIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQML 700
+ TVL+IAHRL V+ AH I+VL +G++ + QL LY++LVQ++++
Sbjct: 648 --WNSRGDRTVLVIAHRLQAVQRAHQILVLQEGKLQKLA---QLQEGQDLYSRLVQQRLM 702
>gi|73747917 transporter 2, ATP-binding cassette, sub-family B
isoform 2 [Homo sapiens]
Length = 653
Score = 412 bits (1060), Expect = e-115
Identities = 239/595 (40%), Positives = 346/595 (58%), Gaps = 69/595 (11%)
Query: 89 VCLFVGIYAMVKLLLFSEVRRP----IRDPWFWALFVWTYISLGASFLLWWLLSTVRPGT 144
+CL + ++ L+ R P PW W L + GA+ L W L + + P
Sbjct: 69 LCLATPLTVSLRALVAGASRAPPARVASAPWSWLL-----VGYGAAGLSWSLWAVLSP-- 121
Query: 145 QALEPGAATEAEGFPGSGRPPPEQASGATLQ-KLLSYTKPDVAFLVAASFFLIVAALGET 203
PG+ +Q + L +LL ++PD+ LVAA FFL++A LGET
Sbjct: 122 --------------PGAQEKEQDQVNNKVLMWRLLKLSRPDLPLLVAAFFFLVLAVLGET 167
Query: 204 FLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRN 263
+P+Y+GR ID + F++A+ +CL + GSS +AG RGG FT +R+N+R+R
Sbjct: 168 LIPHYSGRVIDILGGDFDPHAFASAIFFMCLFSFGSSLSAGCRGGCFTYTMSRINLRIRE 227
Query: 264 CLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFS 323
LF SL+ Q+ FF E +TG+L SRL+SDTT++S+ + N NV LR+ VKV G+ FM S
Sbjct: 228 QLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLS 287
Query: 324 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFAN 383
+S +L+L++ + P + +Y ++ + +E+Q+A+ARA E + ++TVRSF
Sbjct: 288 ISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGA 347
Query: 384 EEEEAEVY---LRKLQQVYKLNRKEAAAYMY----------------------------- 411
EE E Y L + +Q+Y E A Y+
Sbjct: 348 EEHEVCRYKEALEQCRQLYWRRDLERALYLLVRRVLHLGVQMLMLSCGLQQMQDGELTQG 407
Query: 412 ----YVWGSGSVGS-------VYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGR 460
++ SVGS +Y ++ VGAAEKVF ++DRQP + G+LAP L+G
Sbjct: 408 SLLSFMIYQESVGSYVQTLVYIYGDMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGV 467
Query: 461 VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRV 520
V F++V+F Y RP VL+ ++F+L PG+VTALVGP+GSGKS+ +L+N Y GG+V
Sbjct: 468 VKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Query: 521 LLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHG 580
LLD KPIS Y+H YLH + V QEPVLF+ S+ +NI+YGL + + V+ AAQ A+A
Sbjct: 528 LLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADD 587
Query: 581 FIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESE 635
FI E++ G T+ GEKG+QL+ GQKQR+A+ARALVR+P VLILDEATSALD + E
Sbjct: 588 FIQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCE 642
>gi|9665248 transporter 1, ATP-binding cassette, sub-family B [Homo
sapiens]
Length = 808
Score = 409 bits (1050), Expect = e-114
Identities = 228/579 (39%), Positives = 349/579 (60%), Gaps = 46/579 (7%)
Query: 164 PPPEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMD 223
P + SG +++LL + L +++++LGE +P++TGR D I+ S D
Sbjct: 223 PGGQGGSGNPVRRLLGCLGSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSAD 282
Query: 224 QFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTG 283
F+ + ++ +L I S+ + GI+ ++ L+ +F +++ QET FF +N+TG
Sbjct: 283 TFTRNLTLMSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTG 342
Query: 284 DLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVS 343
+++SR+T DT+ +SD +S+N+++FL V+ ++ M S L++VT + P++ ++
Sbjct: 343 NIMSRVTEDTSTLSDSLSENLSLFLWYLVRGLCLLGIMLWGSVSLTMVTLITLPLLFLLP 402
Query: 344 NIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNR 403
GK+Y+ L +V+ +LA++S A E +SAM TVRSFANEE EA+ + KLQ++ LN+
Sbjct: 403 KKVGKWYQLLEVQVRESLAKSSQVAIEALSAMPTVRSFANEEGEAQKFREKLQEIKTLNQ 462
Query: 404 KEAAAYMYYVWG---------------------SGSVGS--------------------- 421
KEA AY W SG+V S
Sbjct: 463 KEAVAYAVNSWTTSISGMLLKVGILYIGGQLVTSGAVSSGNLVTFVLYQMQFTQAVEVLL 522
Query: 422 -VYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQ 480
+Y + + VG++EK+FE++DR P G L P HLEG V F++V+F Y RP VLQ
Sbjct: 523 SIYPRVQKAVGSSEKIFEYLDRTPRCPPSGLLTPLHLEGLVQFQDVSFAYPNRPDVLVLQ 582
Query: 481 NVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVIS 540
++F+L PG+VTALVGP+GSGKS+ +L+N Y GG++LLDGKP+ Y+H+YLHR ++
Sbjct: 583 GLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVA 642
Query: 541 LVSQEPVLFARSITDNISYGLPTVP-FEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ 599
V QEP +F RS+ +NI+YGL P E + AA K+ AH FI L GY TE E G+Q
Sbjct: 643 AVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGLPQGYDTEVDEAGSQ 702
Query: 600 LSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKH--TVLIIAHR 657
LSGGQ+Q VA+ARAL+R P VLILD+ATSALDA S+ ++Q ++ + +++ +VL+I
Sbjct: 703 LSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQH 762
Query: 658 LSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQ 696
LS VE A I+ L+ G + + GTHQQL+ + G Y +VQ
Sbjct: 763 LSLVEQADHILFLEGGAIREGGTHQQLMEKKGCYWAMVQ 801
>gi|171184400 ATP-binding cassette, sub-family B, member 10 [Homo
sapiens]
Length = 738
Score = 361 bits (926), Expect = 1e-99
Identities = 223/595 (37%), Positives = 339/595 (56%), Gaps = 57/595 (9%)
Query: 159 PGS-GRPPPEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIV 217
PG GR P A +KLL P+ L AA FL ++++ P++ G+ ID I
Sbjct: 141 PGDKGRLRPAAAGLPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIY 200
Query: 218 IQKSMDQFSTAVVIVCLLAIGSSFAAG-----IRGGIFTLIFARLNIRLRNCLFRSLVSQ 272
++D +S + +CL + + F G IR + R+ RLR LF S++ Q
Sbjct: 201 TNPTVD-YSDNLTRLCL-GLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQ 258
Query: 273 ETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVT 332
E +FFD+ RTG+LI+RL+SDT ++ V++N++ LR + + + MF +S L+
Sbjct: 259 EVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFV 318
Query: 333 FMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYL 392
P + +++ IYG+Y ++L+K Q++LA+A+ AEE I ++TVR+F E E E Y
Sbjct: 319 LSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYA 378
Query: 393 RKLQQVYKLNRKEAAA----------------------------------------YMYY 412
K+ V +L RKEA A MY
Sbjct: 379 SKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYA 438
Query: 413 VWGSGSVG---SVYSGLMQGVGAAEKVFEFIDRQPTMVHDGS--LAPDHLEGRVDFENVT 467
W S+G S YS LM+G+GA +++E ++R+P + + L +G ++F+NV
Sbjct: 439 FWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVH 498
Query: 468 FTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPI 527
F Y RP + Q+ S S+ G VTALVGPSGSGKS+ +++L Y G + LDG I
Sbjct: 499 FAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDI 558
Query: 528 SAYDHKYLHRVISLVSQEPVLFARSITDNISYGLP---TVPFEMVVEAAQKANAHGFIME 584
+ +L I VSQEP+LF+ SI +NI+YG +V E + A+ ANA FI
Sbjct: 559 RQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRN 618
Query: 585 LQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHG 644
G++T GEKG LSGGQKQR+A+ARAL++NP +L+LDEATSALDAE+EYL+Q+A+
Sbjct: 619 FPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDR 678
Query: 645 NLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQ-GGLYAKLVQRQ 698
+ TVL+IAHRLST+++A+++ VLD+G++ + G H++LL++ G+Y KL+ +Q
Sbjct: 679 LMDGRTVLVIAHRLSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNKQ 733
>gi|156105685 ATP-binding cassette, sub-family B, member 8 [Homo
sapiens]
Length = 718
Score = 333 bits (854), Expect = 3e-91
Identities = 215/603 (35%), Positives = 327/603 (54%), Gaps = 54/603 (8%)
Query: 151 AATEAEGFPGSGRPPPEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTG 210
A EAE P + P S + + P + L A + AAL +P G
Sbjct: 94 ALCEAEEAPPASSTPHVVGSRFNWKLFWQFLHPHLLVLGVAVVLALGAALVNVQIPLLLG 153
Query: 211 RAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRG----GIFTLIF---ARLNIRLRN 263
+ ++ +V + + D + + L+ G++G G L+ R+ + +R
Sbjct: 154 QLVE-VVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRR 212
Query: 264 CLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFS 323
LF SL+ Q+ +FFD N+TG L+SRLT+D I+ LR+ +V G +V +
Sbjct: 213 ALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSM 272
Query: 324 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFAN 383
LS +L+L+ + P +M V + G ++LS++ Q +ARA A+E + ++TVR+FA
Sbjct: 273 LSTRLTLLLMVATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAM 332
Query: 384 EEEEAEVYLRKLQ----QVYKLNRKEAA-------AYMYYVWGSGSVGS----------- 421
E+ E E Y +L+ + +L R A A+ V G+ +G
Sbjct: 333 EQREEERYGAELEACRCRAEELGRGIALFQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGG 392
Query: 422 ---------------------VYSGLMQGVGAAEKVFEFIDRQPTMVHDGS--LAPDHLE 458
++ +++G+ A +VFE++ P + G + + L
Sbjct: 393 DLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLR 452
Query: 459 GRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGG 518
G V F+NV F+Y RP +VL++ + +L PGK+ ALVG SG GK++ ++LE FY G
Sbjct: 453 GSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAG 512
Query: 519 RVLLDGKPISAYDHKYLH-RVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKAN 577
V+LDG+ + D +L +V+ +SQEPVLF +I +NI +G E V AA++AN
Sbjct: 513 VVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYTAAREAN 572
Query: 578 AHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYL 637
AH FI +GY+T GE+G LSGGQKQR+A+ARAL++ P VLILDEATSALDAESE +
Sbjct: 573 AHEFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERV 632
Query: 638 IQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQR 697
+Q+A+ TVL+IAHRLSTV AH IVV+ GRV + GTH++LL +GGLYA+L++R
Sbjct: 633 VQEALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLKKGGLYAELIRR 692
Query: 698 QML 700
Q L
Sbjct: 693 QAL 695
>gi|21536378 ATP-binding cassette, sub-family B (MDR/TAP), member 11
[Homo sapiens]
Length = 1321
Score = 302 bits (773), Expect = 8e-82
Identities = 192/587 (32%), Positives = 308/587 (52%), Gaps = 58/587 (9%)
Query: 164 PPPEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTG--RAIDGIVIQKS 221
P E+ A ++++L ++ P+ +++ S + AA+ T P Y I G
Sbjct: 731 PVQEEVEPAPVRRILKFSAPEWPYMLVGS---VGAAVNGTVTPLYAFLFSQILGTFSIPD 787
Query: 222 MDQFSTAVVIVCLLAIG----SSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFF 277
++ + + VCLL + S F ++G F L RLR FR+++ Q+ ++F
Sbjct: 788 KEEQRSQINGVCLLFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWF 847
Query: 278 DE--NRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMG 335
D+ N G L +RL +D + V I + + + VT ++ FS SW+LSLV
Sbjct: 848 DDLRNSPGALTTRLATDASQVQGAAGSQIGMIVNSFTNVTVAMIIAFSFSWKLSLVILCF 907
Query: 336 FPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKL 395
FP + + + + + AL E +S ++TV E E +L
Sbjct: 908 FPFLALSGATQTRMLTGFASRDKQALEMVGQITNEALSNIRTVAGIGKERRFIEALETEL 967
Query: 396 QQVYKLNRKEA-------------------AAYMYYVWGSGSVGSVYSGLMQGVGA---- 432
++ +K ++A A+Y Y + + G +S + + + A
Sbjct: 968 EKPFKTAIQKANIYGFCFAFAQCIMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLS 1027
Query: 433 --------------------AEKVFEFIDRQP--TMVHDGSLAPDHLEGRVDFENVTFTY 470
A + F+ +DRQP ++ + D+ +G++DF + FTY
Sbjct: 1028 ATALGRAFSYTPSYAKAKISAARFFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTY 1087
Query: 471 RTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAY 530
+RP +QVL +S S+SPG+ A VG SG GKS+ + +LE FY + G+V++DG
Sbjct: 1088 PSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKV 1147
Query: 531 DHKYLHRVISLVSQEPVLFARSITDNISYGLPT--VPFEMVVEAAQKANAHGFIMELQDG 588
+ ++L I +VSQEPVLFA SI DNI YG T +P E V+ AA++A H F+M L +
Sbjct: 1148 NVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEK 1207
Query: 589 YSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQK 648
Y T G +G+QLS G+KQR+A+ARA+VR+P +L+LDEATSALD ESE +Q A+ +
Sbjct: 1208 YETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREG 1267
Query: 649 HTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLV 695
T ++IAHRLST+++A +I V+ +G V+++GTH++L+AQ G Y KLV
Sbjct: 1268 RTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHEELMAQKGAYYKLV 1314
Score = 285 bits (730), Expect = 8e-77
Identities = 176/546 (32%), Positives = 279/546 (51%), Gaps = 70/546 (12%)
Query: 204 FLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRN 263
F YY G A+ ++ T + +C I + AR ++R
Sbjct: 141 FASYYAGIAVAVLI---------TGYIQICFWVIAA---------------ARQIQKMRK 176
Query: 264 CLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFS 323
FR ++ E +FD N G+L +R + D ++D ++ + +F++ + F
Sbjct: 177 FYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQRMTSTICGFLLGFF 236
Query: 324 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFAN 383
W+L+LV P+I + + G + + A A+A A+E IS+M+TV +F
Sbjct: 237 RGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVADEVISSMRTVAAFGG 296
Query: 384 EEEEAEVYLRKLQQVYKLNRKEAAAYMYY---VW-------------GS----------- 416
E+ E E Y + L + ++ ++ VW GS
Sbjct: 297 EKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYALAFWYGSTLVLDEGEYTP 356
Query: 417 -----------------GSVGSVYSGLMQGVGAAEKVFEFIDRQPTM--VHDGSLAPDHL 457
G+ G AA +FE IDR+P + + + D +
Sbjct: 357 GTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKPIIDCMSEDGYKLDRI 416
Query: 458 EGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEG 517
+G ++F NVTF Y +RP ++L +++ + PG++TALVGPSG+GKS+ + +++ FY
Sbjct: 417 KGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCE 476
Query: 518 GRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKAN 577
G V +DG I + + ++L I +V QEPVLF+ +I +NI YG E +V+AA++AN
Sbjct: 477 GMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEAN 536
Query: 578 AHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYL 637
A+ FIM+L + T GE G Q+SGGQKQRVA+ARAL+RNP +L+LD ATSALD ESE +
Sbjct: 537 AYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAM 596
Query: 638 IQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQR 697
+Q+ + HT++ +AHRLSTV A I+ + G V++GTH++LL + G+Y LV
Sbjct: 597 VQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEELLERKGVYFTLVTL 656
Query: 698 QMLGLQ 703
Q G Q
Sbjct: 657 QSQGNQ 662
>gi|9961252 ATP-binding cassette, subfamily B, member 4 isoform C
[Homo sapiens]
Length = 1232
Score = 298 bits (764), Expect = 9e-81
Identities = 186/491 (37%), Positives = 267/491 (54%), Gaps = 13/491 (2%)
Query: 214 DGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQE 273
D V Q+ + FS +I L I S F ++G F L RLR+ F++++ Q+
Sbjct: 743 DDAVKQQKCNIFS---LIFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQD 799
Query: 274 TSFFDE--NRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLV 331
S+FD+ N TG L +RL +D V + + +N + ++ F WQL+L+
Sbjct: 800 MSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGWQLTLL 859
Query: 332 TFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVY 391
PII + + K +K + L A A E I ++TV S E + +Y
Sbjct: 860 LLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMY 919
Query: 392 LRKLQQVYKLNRKEAAAYMYYVWGSGSVGSVYSGLMQGVGAAEKVFEFIDRQPTM--VHD 449
+ KL Y++ +A ++ G S + +A +F +RQP + +
Sbjct: 920 VEKLYGPYRV----FSAIVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQPLIDSYSE 975
Query: 450 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 509
L PD EG + F V F Y TR + VLQ +S + G+ ALVG SG GKS+ V +L
Sbjct: 976 EGLKPDKFEGNITFNEVVFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLL 1035
Query: 510 ENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYG--LPTVPFE 567
E FY G VLLDG+ + ++L + +VSQEP+LF SI +NI+YG V +
Sbjct: 1036 ERFYDPLAGTVLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQD 1095
Query: 568 MVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEAT 627
+V AA+ AN H FI L Y T G+KG QLSGGQKQR+A+ARAL+R P +L+LDEAT
Sbjct: 1096 EIVSAAKAANIHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEAT 1155
Query: 628 SALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQ 687
SALD ESE ++Q+A+ + T ++IAHRLST+++A LIVV GRV + GTHQQLLAQ
Sbjct: 1156 SALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQ 1215
Query: 688 GGLYAKLVQRQ 698
G+Y +V Q
Sbjct: 1216 KGIYFSMVSVQ 1226
Score = 295 bits (755), Expect = 1e-79
Identities = 176/514 (34%), Positives = 282/514 (54%), Gaps = 45/514 (8%)
Query: 235 LAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTT 294
L G AA I+ +TL R ++R F +++ QE +FD N T +L +RLT D +
Sbjct: 123 LGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDIS 182
Query: 295 MVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLS 354
+S+ + + +F + + F W+L+LV PI+ + + ++ K S
Sbjct: 183 KISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFS 242
Query: 355 KEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEA-------- 406
+ A A+A AEE + A++TV +F + +E E Y + L+ ++ K+A
Sbjct: 243 DKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISMG 302
Query: 407 -------AAYMYYVW-GS----------GSVGSVYSGLMQGV-----------------G 431
A+Y W GS G+ +V+ ++ G G
Sbjct: 303 IAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARG 362
Query: 432 AAEKVFEFIDRQPTM--VHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPG 489
AA +F+ ID P + + PD ++G ++F +V F+Y +R + ++L+ ++ + G
Sbjct: 363 AAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSG 422
Query: 490 KVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLF 549
+ ALVG SG GKS+ V +++ Y + G + +DG+ I ++ YL +I +VSQEPVLF
Sbjct: 423 QTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLF 482
Query: 550 ARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVA 609
+ +I +NI YG V + + +A ++ANA+ FIM+L + T GE+GAQLSGGQKQR+A
Sbjct: 483 STTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIA 542
Query: 610 MARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVV 669
+ARALVRNP +L+LDEATSALD ESE +Q A+ + T ++IAHRLSTV +A +I
Sbjct: 543 IARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAG 602
Query: 670 LDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQ 703
+ G +V+QG+H +L+ + G+Y KLV Q G Q
Sbjct: 603 FEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQ 636
>gi|42741659 ATP-binding cassette, subfamily B, member 1 [Homo
sapiens]
Length = 1280
Score = 296 bits (759), Expect = 3e-80
Identities = 176/522 (33%), Positives = 291/522 (55%), Gaps = 49/522 (9%)
Query: 235 LAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTT 294
+ G AA I+ + L R ++R F +++ QE +FD + G+L +RLT D +
Sbjct: 121 IGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVS 180
Query: 295 MVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLS 354
+++ + I +F ++ + F+ W+L+LV P++ + + ++ K +
Sbjct: 181 KINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFT 240
Query: 355 KEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEA-------- 406
+ A A+A AEE ++A++TV +F +++E E Y + L++ ++ K+A
Sbjct: 241 DKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIG 300
Query: 407 -------AAYMYYVW--------GSGSVG---SVYSGLMQGV-----------------G 431
A+Y W G S+G +V+ ++ G G
Sbjct: 301 AAFLLIYASYALAFWYGTTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARG 360
Query: 432 AAEKVFEFIDRQPTM--VHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPG 489
AA ++F+ ID +P++ PD+++G ++F NV F+Y +R ++L+ ++ + G
Sbjct: 361 AAYEIFKIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSG 420
Query: 490 KVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLF 549
+ ALVG SG GKS+ V +++ Y G V +DG+ I + ++L +I +VSQEPVLF
Sbjct: 421 QTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLF 480
Query: 550 ARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVA 609
A +I +NI YG V + + +A ++ANA+ FIM+L + T GE+GAQLSGGQKQR+A
Sbjct: 481 ATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIA 540
Query: 610 MARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVV 669
+ARALVRNP +L+LDEATSALD ESE ++Q A+ + T ++IAHRLSTV +A +I
Sbjct: 541 IARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAG 600
Query: 670 LDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLG----LQPAAD 707
D G +V++G H +L+ + G+Y KLV Q G L+ AAD
Sbjct: 601 FDDGVIVEKGNHDELMKEKGIYFKLVTMQTAGNEVELENAAD 642
Score = 295 bits (756), Expect = 8e-80
Identities = 188/491 (38%), Positives = 265/491 (53%), Gaps = 49/491 (9%)
Query: 257 LNIRLRNCLFRSLVSQETSFFDE--NRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKV 314
L RLR +FRS++ Q+ S+FD+ N TG L +RL +D V + + V +N +
Sbjct: 784 LTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANL 843
Query: 315 TGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISA 374
++ F WQL+L+ PII + + K + + + L + A E I
Sbjct: 844 GTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIEN 903
Query: 375 MKTVRSFANEEEEAEVYLRKLQQVYKLNRKEA----------AAYMYY------------ 412
+TV S E++ +Y + LQ Y+ + ++A A MY+
Sbjct: 904 FRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYL 963
Query: 413 ------------------VWGSGSVGSVYSGLMQGVGA---AEKVFEFIDRQPTM--VHD 449
V+G+ +VG V S A A + I++ P +
Sbjct: 964 VAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYST 1023
Query: 450 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 509
L P+ LEG V F V F Y TRP VLQ +S + G+ ALVG SG GKS+ V +L
Sbjct: 1024 EGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLL 1083
Query: 510 ENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYG--LPTVPFE 567
E FY G+VLLDGK I + ++L + +VSQEP+LF SI +NI+YG V E
Sbjct: 1084 ERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQE 1143
Query: 568 MVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEAT 627
+V AA++AN H FI L + YST+ G+KG QLSGGQKQR+A+ARALVR P +L+LDEAT
Sbjct: 1144 EIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEAT 1203
Query: 628 SALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQ 687
SALD ESE ++Q+A+ + T ++IAHRLST+++A LIVV GRV + GTHQQLLAQ
Sbjct: 1204 SALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQ 1263
Query: 688 GGLYAKLVQRQ 698
G+Y +V Q
Sbjct: 1264 KGIYFSMVSVQ 1274
>gi|9961250 ATP-binding cassette, subfamily B, member 4 isoform B
[Homo sapiens]
Length = 1286
Score = 295 bits (755), Expect = 1e-79
Identities = 176/514 (34%), Positives = 282/514 (54%), Gaps = 45/514 (8%)
Query: 235 LAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTT 294
L G AA I+ +TL R ++R F +++ QE +FD N T +L +RLT D +
Sbjct: 123 LGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDIS 182
Query: 295 MVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLS 354
+S+ + + +F + + F W+L+LV PI+ + + ++ K S
Sbjct: 183 KISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFS 242
Query: 355 KEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEA-------- 406
+ A A+A AEE + A++TV +F + +E E Y + L+ ++ K+A
Sbjct: 243 DKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISMG 302
Query: 407 -------AAYMYYVW-GS----------GSVGSVYSGLMQGV-----------------G 431
A+Y W GS G+ +V+ ++ G G
Sbjct: 303 IAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARG 362
Query: 432 AAEKVFEFIDRQPTM--VHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPG 489
AA +F+ ID P + + PD ++G ++F +V F+Y +R + ++L+ ++ + G
Sbjct: 363 AAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSG 422
Query: 490 KVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLF 549
+ ALVG SG GKS+ V +++ Y + G + +DG+ I ++ YL +I +VSQEPVLF
Sbjct: 423 QTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLF 482
Query: 550 ARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVA 609
+ +I +NI YG V + + +A ++ANA+ FIM+L + T GE+GAQLSGGQKQR+A
Sbjct: 483 STTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIA 542
Query: 610 MARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVV 669
+ARALVRNP +L+LDEATSALD ESE +Q A+ + T ++IAHRLSTV +A +I
Sbjct: 543 IARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAG 602
Query: 670 LDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQ 703
+ G +V+QG+H +L+ + G+Y KLV Q G Q
Sbjct: 603 FEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQ 636
Score = 285 bits (728), Expect = 1e-76
Identities = 194/541 (35%), Positives = 278/541 (51%), Gaps = 59/541 (10%)
Query: 214 DGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQE 273
D V Q+ + FS +I L I S F ++G F L RLR+ F++++ Q+
Sbjct: 743 DDAVKQQKCNIFS---LIFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQD 799
Query: 274 TSFFDE--NRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLV 331
S+FD+ N TG L +RL +D V + + +N + ++ F WQL+L+
Sbjct: 800 MSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGWQLTLL 859
Query: 332 TFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVY 391
PII + + K +K + L A A E I ++TV S E + +Y
Sbjct: 860 LLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMY 919
Query: 392 LRKLQQVYKLNRKEA----------AAYMYYVWGS----------------GSVGSVYSG 425
+ KL Y+ + ++A A+MY+ + V V+S
Sbjct: 920 VEKLYGPYRNSVQKAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSA 979
Query: 426 LMQGVGA-----------------AEKVFEFIDRQPTM--VHDGSLAPDHLEGRVDFENV 466
++ G A A +F +RQP + + L PD EG + F V
Sbjct: 980 IVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQPLIDSYSEEGLKPDKFEGNITFNEV 1039
Query: 467 TFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFY-PLEG------GR 519
F Y TR + VLQ +S + G+ ALVG SG GKS+ V +LE FY PL G G
Sbjct: 1040 VFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGF 1099
Query: 520 VLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYG--LPTVPFEMVVEAAQKAN 577
LLDG+ + ++L + +VSQEP+LF SI +NI+YG V + +V AA+ AN
Sbjct: 1100 QLLDGQEAKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAAN 1159
Query: 578 AHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYL 637
H FI L Y T G+KG QLSGGQKQR+A+ARAL+R P +L+LDEATSALD ESE +
Sbjct: 1160 IHPFIETLPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKV 1219
Query: 638 IQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQR 697
+Q+A+ + T ++IAHRLST+++A LIVV GRV + GTHQQLLAQ G+Y +V
Sbjct: 1220 VQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSV 1279
Query: 698 Q 698
Q
Sbjct: 1280 Q 1280
>gi|4505771 ATP-binding cassette, subfamily B, member 4 isoform A
[Homo sapiens]
Length = 1279
Score = 295 bits (755), Expect = 1e-79
Identities = 176/514 (34%), Positives = 282/514 (54%), Gaps = 45/514 (8%)
Query: 235 LAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTT 294
L G AA I+ +TL R ++R F +++ QE +FD N T +L +RLT D +
Sbjct: 123 LGAGVLVAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDIS 182
Query: 295 MVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLS 354
+S+ + + +F + + F W+L+LV PI+ + + ++ K S
Sbjct: 183 KISEGIGDKVGMFFQAVATFFAGFIVGFIRGWKLTLVIMAISPILGLSAAVWAKILSAFS 242
Query: 355 KEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEA-------- 406
+ A A+A AEE + A++TV +F + +E E Y + L+ ++ K+A
Sbjct: 243 DKELAAYAKAGAVAEEALGAIRTVIAFGGQNKELERYQKHLENAKEIGIKKAISANISMG 302
Query: 407 -------AAYMYYVW-GS----------GSVGSVYSGLMQGV-----------------G 431
A+Y W GS G+ +V+ ++ G G
Sbjct: 303 IAFLLIYASYALAFWYGSTLVISKEYTIGNAMTVFFSILIGAFSVGQAAPCIDAFANARG 362
Query: 432 AAEKVFEFIDRQPTM--VHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPG 489
AA +F+ ID P + + PD ++G ++F +V F+Y +R + ++L+ ++ + G
Sbjct: 363 AAYVIFDIIDNNPKIDSFSERGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSG 422
Query: 490 KVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLF 549
+ ALVG SG GKS+ V +++ Y + G + +DG+ I ++ YL +I +VSQEPVLF
Sbjct: 423 QTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFNVNYLREIIGVVSQEPVLF 482
Query: 550 ARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVA 609
+ +I +NI YG V + + +A ++ANA+ FIM+L + T GE+GAQLSGGQKQR+A
Sbjct: 483 STTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQKFDTLVGERGAQLSGGQKQRIA 542
Query: 610 MARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVV 669
+ARALVRNP +L+LDEATSALD ESE +Q A+ + T ++IAHRLSTV +A +I
Sbjct: 543 IARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTTIVIAHRLSTVRNADVIAG 602
Query: 670 LDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQ 703
+ G +V+QG+H +L+ + G+Y KLV Q G Q
Sbjct: 603 FEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQ 636
Score = 290 bits (742), Expect = 3e-78
Identities = 192/534 (35%), Positives = 276/534 (51%), Gaps = 52/534 (9%)
Query: 214 DGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQE 273
D V Q+ + FS +I L I S F ++G F L RLR+ F++++ Q+
Sbjct: 743 DDAVKQQKCNIFS---LIFLFLGIISFFTFFLQGFTFGKAGEILTRRLRSMAFKAMLRQD 799
Query: 274 TSFFDE--NRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLV 331
S+FD+ N TG L +RL +D V + + +N + ++ F WQL+L+
Sbjct: 800 MSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIAQNIANLGTGIIISFIYGWQLTLL 859
Query: 332 TFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVY 391
PII + + K +K + L A A E I ++TV S E + +Y
Sbjct: 860 LLAVVPIIAVSGIVEMKLLAGNAKRDKKELEAAGKIATEAIENIRTVVSLTQERKFESMY 919
Query: 392 LRKLQQVYKLNRKEA----------AAYMYYVWGS----------------GSVGSVYSG 425
+ KL Y+ + ++A A+MY+ + V V+S
Sbjct: 920 VEKLYGPYRNSVQKAHIYGITFSISQAFMYFSYAGCFRFGAYLIVNGHMRFRDVILVFSA 979
Query: 426 LMQGVGA-----------------AEKVFEFIDRQPTM--VHDGSLAPDHLEGRVDFENV 466
++ G A A +F +RQP + + L PD EG + F V
Sbjct: 980 IVFGAVALGHASSFAPDYAKAKLSAAHLFMLFERQPLIDSYSEEGLKPDKFEGNITFNEV 1039
Query: 467 TFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKP 526
F Y TR + VLQ +S + G+ ALVG SG GKS+ V +LE FY G VLLDG+
Sbjct: 1040 VFNYPTRANVPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLDGQE 1099
Query: 527 ISAYDHKYLHRVISLVSQEPVLFARSITDNISYG--LPTVPFEMVVEAAQKANAHGFIME 584
+ ++L + +VSQEP+LF SI +NI+YG V + +V AA+ AN H FI
Sbjct: 1100 AKKLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIET 1159
Query: 585 LQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHG 644
L Y T G+KG QLSGGQKQR+A+ARAL+R P +L+LDEATSALD ESE ++Q+A+
Sbjct: 1160 LPHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK 1219
Query: 645 NLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQ 698
+ T ++IAHRLST+++A LIVV GRV + GTHQQLLAQ G+Y +V Q
Sbjct: 1220 AREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1273
>gi|148612844 ATP-binding cassette, sub-family B, member 5 [Homo
sapiens]
Length = 812
Score = 265 bits (678), Expect = 9e-71
Identities = 182/585 (31%), Positives = 293/585 (50%), Gaps = 66/585 (11%)
Query: 173 TLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYT---GRAI------DGIVIQKSMD 223
+L K+L KP+ F+V + + + L T P ++ + I D ++ +
Sbjct: 232 SLLKILKLNKPEWPFVVLGT---LASVLNGTVHPVFSIIFAKIITMFGNNDKTTLKHDAE 288
Query: 224 QFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDE--NR 281
+S VI+ ++ S F G+ G I L +RLR+ F++++ Q+ ++FDE N
Sbjct: 289 IYSMIFVILGVICFVSYFMQGLFYGRAGEI---LTMRLRHLAFKAMLYQDIAWFDEKENS 345
Query: 282 TGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMM 341
TG L + L D + I V +N + V+ F W+++ + P++ +
Sbjct: 346 TGGLTTILAIDIAQIQGATGSRIGVLTQNATNMGLSVIISFIYGWEMTFLILSIAPVLAV 405
Query: 342 VSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKL 401
I + + + L A A E + ++T+ S E+ ++Y LQ ++
Sbjct: 406 TGMIETAAMTGFANKDKQELKHAGKIATEALENIRTIVSLTREKAFEQMYEEMLQTQHRN 465
Query: 402 NRKEAA----------AYMYYVWGSG----------------SVGSVYSGLMQGVGA--- 432
K+A A++Y+ + +G + V++ + G A
Sbjct: 466 TSKKAQIIGSCYAFSHAFIYFAYAAGFRFGAYLIQAGRMTPEGMFIVFTAIAYGAMAIGE 525
Query: 433 --------------AEKVFEFIDRQPTM---VHDGSLAPDHLEGRVDFENVTFTYRTRPH 475
A +F ++++P + +G PD EG ++F V+F Y RP
Sbjct: 526 TLVLAPEYSKAKSGAAHLFALLEKKPNIDSRSQEGK-KPDTCEGNLEFREVSFFYPCRPD 584
Query: 476 TQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYL 535
+L+ +S S+ GK A VG SG GKS+ V +L+ Y G+VL DG + ++L
Sbjct: 585 VFILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDAKELNVQWL 644
Query: 536 HRVISLVSQEPVLFARSITDNISYG--LPTVPFEMVVEAAQKANAHGFIMELQDGYSTET 593
I++V QEPVLF SI +NI+YG VP + + EAA AN H FI L + Y+T+
Sbjct: 645 RSQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANAANIHSFIEGLPEKYNTQV 704
Query: 594 GEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLI 653
G KGAQLSGGQKQR+A+ARAL++ P +L+LDEATSALD +SE ++Q A+ T L+
Sbjct: 705 GLKGAQLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLV 764
Query: 654 IAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQ 698
+ HRLS +++A LIVVL G++ +QGTHQ+LL +Y KLV Q
Sbjct: 765 VTHRLSAIQNADLIVVLHNGKIKEQGTHQELLRNRDIYFKLVNAQ 809
Score = 171 bits (432), Expect = 3e-42
Identities = 89/178 (50%), Positives = 124/178 (69%)
Query: 521 LLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHG 580
++D I A + ++ I +VSQEPVLF +I++NI YG V E + AA++ANA+
Sbjct: 1 MVDENDIRALNVRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTDEEMERAAREANAYD 60
Query: 581 FIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQ 640
FIME + ++T GEKGAQ+SGGQKQR+A+ARALVRNP +LILDEATSALD+ES+ +Q
Sbjct: 61 FIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQA 120
Query: 641 AIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQ 698
A+ + T +++AHRLST+ A LIV L G + ++G H +L+A+ GLY LV Q
Sbjct: 121 ALEKASKGRTTIVVAHRLSTIRSADLIVTLKDGMLAEKGAHAELMAKRGLYYSLVMSQ 178
>gi|9955963 ATP-binding cassette, sub-family B, member 6 [Homo
sapiens]
Length = 842
Score = 219 bits (557), Expect = 9e-57
Identities = 182/659 (27%), Positives = 307/659 (46%), Gaps = 81/659 (12%)
Query: 115 WFWA-----------LFVWTYISLGASFLLWWLLSTVRPGTQAL---EPGAATEAEGFPG 160
W+WA L+V Y+ G F+L +RP + L E E
Sbjct: 173 WWWARADLGQQVQFSLWVLRYVVSGGLFVLGLWAPGLRPQSYTLQVHEEDQDVERSQVRS 232
Query: 161 SGRPPPEQASGATLQKLLSYTKP------DVAFLVAASFFLIVAALGETFLPYYTGRAID 214
+ + + G L+ L Y P + L+ + AL +Y R I
Sbjct: 233 AAQQSTWRDFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFY--RNIV 290
Query: 215 GIVIQK----SMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARL----NIRLRNCLF 266
++ +K S+ T+ V + L G + + G + T ++ R+ + R+ +F
Sbjct: 291 NLLTEKAPWNSLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRRVELLIF 350
Query: 267 RSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNI-NVFLRNTVKVTGVVVF-MFSL 324
L + RTG+++ T+ V+ L+S + NV + G++ F MF
Sbjct: 351 SHLHELSLRWHLGRRTGEVLRIADRGTSSVTGLLSYLVFNVIPTLADIIIGIIYFSMFFN 410
Query: 325 SWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANE 384
+W L+ F+ + + ++ + ++ + + + A +++ +TV+ + E
Sbjct: 411 AW-FGLIVFLCMSLYLTLTIVVTEWRTKFRRAMNTQENATRARAVDSLLNFETVKYYNAE 469
Query: 385 EEEAEVYLRKLQQVYKLNRKEAAAYM---------------------------------- 410
E E Y + + L K +A+ +
Sbjct: 470 SYEVERYREAIIKYQGLEWKSSASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGD 529
Query: 411 YYVWGSGSV---------GSVYSGLMQGVGAAEKVFEFIDRQPTMVHD--GSLAPDHLEG 459
Y ++G+ + G+ Y + E +F+ + ++ T V D G+ +G
Sbjct: 530 YVLFGTYIIQLYMPLNWFGTYYRMIQTNFIDMENMFDLL-KEETEVKDLPGAGPLRFQKG 588
Query: 460 RVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGR 519
R++FENV F+Y T LQ+VSF++ PG+ ALVGPSG+GKS+ + +L FY + G
Sbjct: 589 RIEFENVHFSYADGRET--LQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGC 646
Query: 520 VLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAH 579
+ +DG+ IS L I +V Q+ VLF +I DNI YG T + V AAQ A H
Sbjct: 647 IRIDGQDISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIH 706
Query: 580 GFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQ 639
IM +GY T+ GE+G +LSGG+KQRVA+AR +++ P +++LDEATSALD +E IQ
Sbjct: 707 DAIMAFPEGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQ 766
Query: 640 QAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQ 698
++ T +++AHRLSTV +A I+V+ G +V++G H+ LL++GG+YA + Q Q
Sbjct: 767 ASLAKVCANRTTIVVAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQ 825
>gi|42490749 ATP-binding cassette, sub-family B, member 7 [Homo
sapiens]
Length = 753
Score = 189 bits (480), Expect = 8e-48
Identities = 173/602 (28%), Positives = 281/602 (46%), Gaps = 81/602 (13%)
Query: 174 LQKLLSYT----KPDVAFLVAASF-FLIVAALGETFLPYYTGRAIDGI-VIQKSMDQFST 227
++ +LSY +PD+ VA S FL A +P+ A+D + + +M S
Sbjct: 122 IKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSD 181
Query: 228 AVVIVCLLAI-----------GSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSF 276
A V +A G++F +R +F + R+ +F L + + F
Sbjct: 182 APNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGF 241
Query: 277 FDENRTGDLISRLTSDTTMVSDLVSQ---NINVFLRNTVKVTGVVVF----MFSLSWQLS 329
+TG L + T +S ++S N+ + + V+GV+ + F+L +
Sbjct: 242 HLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIMFEVMLVSGVLYYKCGAQFALVTLGT 301
Query: 330 LVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAE 389
L T+ F + + ++ R E+ A A N A +++ +TV+ F NE EA+
Sbjct: 302 LGTYTAFTVAVT------RWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNERYEAQ 355
Query: 390 VY-----------LRKLQQVYKLNRKEAAAYMY------------YVWGSGSVG------ 420
Y L+ + LN ++A + V G+ +VG
Sbjct: 356 RYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGIVAGTLTVGDLVMVN 415
Query: 421 --------------SVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPD----HLEGRVD 462
+VY Q + +F + + T + D +A V
Sbjct: 416 GLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLL-KVDTQIKDKVMASPLQITPQTATVA 474
Query: 463 FENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLL 522
F+NV F Y +VL +SF + GK A+VG SGSGKS+ V +L FY + G + L
Sbjct: 475 FDNVHFEYIEGQ--KVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYL 532
Query: 523 DGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFI 582
G+ I + L R + +V Q+ VLF +I N+ YG + E V A+ A H I
Sbjct: 533 AGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAI 592
Query: 583 MELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAI 642
+ + GY T+ GE+G +LSGG+KQRVA+ARA++++PPV++ DEATS+LD+ +E I A+
Sbjct: 593 LRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAM 652
Query: 643 HGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQ-GGLYAKLVQRQMLG 701
++ T + IAHRLSTV A I+VLD+G+V ++GTH LLA +Y+++ Q
Sbjct: 653 KDVVKHRTSIFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANPHSIYSEMWHTQSSR 712
Query: 702 LQ 703
+Q
Sbjct: 713 VQ 714
>gi|4557481 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
[Homo sapiens]
Length = 1545
Score = 152 bits (384), Expect = 1e-36
Identities = 127/508 (25%), Positives = 232/508 (45%), Gaps = 64/508 (12%)
Query: 235 LAIGSSFAAGIRGGIFTLI--------FARLNIRLRNCLFRSLVSQETSFFDENRTGDLI 286
+ +G A G+ GIF I F + L L +++ FFD TG ++
Sbjct: 1022 MRVGVYGALGLAQGIFVFIAHFWSAFGFVHASNILHKQLLNNILRAPMRFFDTTPTGRIV 1081
Query: 287 SRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIY 346
+R D + V D + Q++ ++ + + +V + + +++ I + V Y
Sbjct: 1082 NRFAGDISTVDDTLPQSLRSWITCFLGIISTLVMICMATPVFTIIVIPLGIIYVSVQMFY 1141
Query: 347 GKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEE---EEAEVYLRKLQQVY---- 399
++L + + + ET+S + +R+F +++ + EV + Q+
Sbjct: 1142 VSTSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEVRIDTNQKCVFSWI 1201
Query: 400 KLNRKEA-------------AAYMYYVW----GSGSVGSVYSGLMQ-------------- 428
NR A +A M ++ +VG V S +
Sbjct: 1202 TSNRWLAIRLELVGNLTVFFSALMMVIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTSE 1261
Query: 429 ---GVGAAEKVFEF--IDRQPTMVHDGSLAPDH-LEGRVDFENVTFTYRTRPHTQVLQNV 482
+ A E++ E+ ++ + V D PD +G++ F N YR VL+ +
Sbjct: 1262 IETNIVAVERITEYTKVENEAPWVTDKRPPPDWPSKGKIQFNNYQVRYRPELDL-VLRGI 1320
Query: 483 SFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLV 542
+ + + +VG +G+GKSS N L GG++++DG I++ L ++++
Sbjct: 1321 TCDIGSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGQIIIDGVDIASIGLHDLREKLTII 1380
Query: 543 SQEPVLFARSITDNISYGLPTVPF-----EMVVEAAQKANAHGFIMELQDGYSTETGEKG 597
Q+P+LF+ S+ N+ PF E + +A + A+ F+ LQ G S E E G
Sbjct: 1381 PQDPILFSGSLRMNLD------PFNNYSDEEIWKALELAHLKSFVASLQLGLSHEVTEAG 1434
Query: 598 AQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHR 657
LS GQ+Q + + RAL+R +L+LDEAT+A+D E++ LIQ I TV+ IAHR
Sbjct: 1435 GNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDNLIQTTIQNEFAHCTVITIAHR 1494
Query: 658 LSTVEHAHLIVVLDKGRVVQQGTHQQLL 685
L T+ + ++VLD G++++ G+ ++LL
Sbjct: 1495 LHTIMDSDKVMVLDNGKIIECGSPEELL 1522
Score = 97.8 bits (242), Expect = 3e-20
Identities = 70/238 (29%), Positives = 123/238 (51%), Gaps = 22/238 (9%)
Query: 461 VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRV 520
+ F +FT+ V ++V+ + G++ A++GP GSGKSS ++ +
Sbjct: 637 MQFSEASFTWEHDSEATV-RDVNLDIMAGQLVAVIGPVGSGKSSLISAML---------- 685
Query: 521 LLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLP--TVPFEMVVEAAQKANA 578
G+ + + H + + V Q+ + +I DNI +G ++ V+EA
Sbjct: 686 ---GEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNILFGTEFNEKRYQQVLEACALLPD 742
Query: 579 HGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEYL 637
+ L G E GEKG LSGGQKQR+++ARA +N + +LD+ SA+DA +++
Sbjct: 743 ---LEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHVGKHI 799
Query: 638 IQQAI--HGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAK 693
+ + +G L+ T L++ H + + IVVL G +V++G++ LLA+ G +AK
Sbjct: 800 FNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAKKGEFAK 857
>gi|66529005 ATP-binding cassette, sub-family C, member 5 isoform 1
[Homo sapiens]
Length = 1437
Score = 150 bits (380), Expect = 3e-36
Identities = 139/504 (27%), Positives = 228/504 (45%), Gaps = 80/504 (15%)
Query: 245 IRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNI 304
IRG +F R + RL + LFR ++ FFD TG +++R + D V +
Sbjct: 931 IRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQA 990
Query: 305 NVFLRNTVKV---TGVVVFMFSLSWQLSLV--TFMGFPIIMMVSNIYGKYYKRLSKEVQN 359
+F++N + V G++ +F W L V + F ++ +VS + + KRL Q+
Sbjct: 991 EMFIQNVILVFFCVGMIAGVFP--WFLVAVGPLVILFSVLHIVSRVLIRELKRLDNITQS 1048
Query: 360 ALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMY-------- 411
+ +I + T+ ++ +E +L + Q++ L+ +A +++
Sbjct: 1049 PFL---SHITSSIQGLATIHAYNKGQE----FLHRYQEL--LDDNQAPFFLFTCAMRWLA 1099
Query: 412 -----------------YVWGSGSVGSVYSGL---------------MQGVGAAEKVFEF 439
V G + Y+GL ++ E F
Sbjct: 1100 VRLDLISIALITTTGLMIVLMHGQIPPAYAGLAISYAVQLTGLFQFTVRLASETEARFTS 1159
Query: 440 IDR-----------QPTMVHDGSLAPDH-LEGRVDFENVTFTYRTRPHTQVLQNVSFSLS 487
++R P + + + +PD EG V FEN YR VL+ VSF++
Sbjct: 1160 VERINHYIKTLSLEAPARIKNKAPSPDWPQEGEVTFENAEMRYRENLPL-VLKKVSFTIK 1218
Query: 488 PGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPV 547
P + +VG +GSGKSS L L GG + +DG IS L +S++ QEPV
Sbjct: 1219 PKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGVRISDIGLADLRSKLSIIPQEPV 1278
Query: 548 LFARSITDNISYGLPTVPFEMVVE-----AAQKANAHGFIMELQDGYSTETGEKGAQLSG 602
LF+ ++ N+ PF E A ++ + I +L +E E G S
Sbjct: 1279 LFSGTVRSNLD------PFNQYTEDQIWDALERTHMKECIAQLPLKLESEVMENGDNFSV 1332
Query: 603 GQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVE 662
G++Q + +ARAL+R+ +LILDEAT+A+D E++ LIQ+ I T+L IAHRL TV
Sbjct: 1333 GERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVL 1392
Query: 663 HAHLIVVLDKGRVVQQGTHQQLLA 686
+ I+VL +G+VV+ T LL+
Sbjct: 1393 GSDRIMVLAQGQVVEFDTPSVLLS 1416
Score = 103 bits (257), Expect = 6e-22
Identities = 67/247 (27%), Positives = 119/247 (48%), Gaps = 18/247 (7%)
Query: 477 QVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLH 536
+ L ++ + GK+ + G GSGK+S ++ + L G + + G
Sbjct: 576 RTLHSIDLEIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISG------------ 623
Query: 537 RVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEK 596
+ V+Q+ + ++ DNI +G E + L TE GE+
Sbjct: 624 -TFAYVAQQAWILNATLRDNILFG-KEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGER 681
Query: 597 GAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEYLIQQAIHGNLQKHTVLIIA 655
GA LSGGQ+QR+++ARAL + + ILD+ SALDA ++ AI +L+ TVL +
Sbjct: 682 GANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVLFVT 741
Query: 656 HRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEP 715
H+L + ++ + +G + ++GTH++L+ G YA + +LG P + +++
Sbjct: 742 HQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLLLGETPPVEI---NSKK 798
Query: 716 VANGSHK 722
+GS K
Sbjct: 799 ETSGSQK 805
>gi|134142345 ATP-binding cassette, sub-family C, member 1 isoform 3
[Homo sapiens]
Length = 1475
Score = 145 bits (367), Expect = 1e-34
Identities = 125/483 (25%), Positives = 223/483 (46%), Gaps = 59/483 (12%)
Query: 265 LFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGV-VVFMFS 323
L S++ SFF+ +G+L++R + + V ++ + I +F+ + V G +V + +
Sbjct: 996 LLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLA 1055
Query: 324 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFAN 383
++ +G I V Y ++L + + + + ET+ + +R+F
Sbjct: 1056 TPIAAIIIPPLGL-IYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEE 1114
Query: 384 EEE---EAEVYLRKLQQVYK----LNRKEA-----------------AAYMYYVWGSGSV 419
+E ++++ + + Q+ Y NR A A + +G V
Sbjct: 1115 QERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLV 1174
Query: 420 GSVYSGLMQ-----------------GVGAAEKVFEFIDRQ---PTMVHDGSLAPDHLE- 458
G S +Q + A E++ E+ + + P + + + +
Sbjct: 1175 GLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQV 1234
Query: 459 GRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGG 518
GRV+F N YR VL++++ +++ G+ +VG +G+GKSS L G
Sbjct: 1235 GRVEFRNYCLRYR-EDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEG 1293
Query: 519 RVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPF-----EMVVEAA 573
+++DG I+ L I+++ Q+PVLF+ S+ N+ PF E V +
Sbjct: 1294 EIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD------PFSQYSDEEVWTSL 1347
Query: 574 QKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE 633
+ A+ F+ L D E E G LS GQ+Q V +ARAL+R +L+LDEAT+A+D E
Sbjct: 1348 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1407
Query: 634 SEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAK 693
++ LIQ I + TVL IAHRL+T+ ++VLDKG + + G LL Q GL+
Sbjct: 1408 TDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYS 1467
Query: 694 LVQ 696
+ +
Sbjct: 1468 MAK 1470
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/255 (20%), Positives = 97/255 (38%), Gaps = 78/255 (30%)
Query: 452 LAPDHLEGR----------VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSG 501
L PD +E R + N TFT+ R L ++FS+ G + A+VG G G
Sbjct: 625 LEPDSIERRPVKDGGGTNSITVRNATFTW-ARSDPPTLNGITFSIPEGALVAVVGQVGCG 683
Query: 502 KSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGL 561
KSS ++ L G V + G ++ V Q+ + S+ +NI +
Sbjct: 684 KSSLLSALLAEMDKVEGHVAIKGS-------------VAYVPQQAWIQNDSLRENILF-- 728
Query: 562 PTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVL 621
G QL + V A AL+ + +L
Sbjct: 729 -----------------------------------GCQLEEPYYRSVIQACALLPDLEIL 753
Query: 622 ILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTH 681
+ T + + T +++ H +S + +I+V+ G++ + G++
Sbjct: 754 PSGDRT-----------------EIGEKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSY 796
Query: 682 QQLLAQGGLYAKLVQ 696
Q+LLA+ G +A+ ++
Sbjct: 797 QELLARDGAFAEFLR 811
>gi|134142342 ATP-binding cassette, sub-family C, member 1 isoform 4
[Homo sapiens]
Length = 1416
Score = 145 bits (367), Expect = 1e-34
Identities = 125/483 (25%), Positives = 223/483 (46%), Gaps = 59/483 (12%)
Query: 265 LFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGV-VVFMFS 323
L S++ SFF+ +G+L++R + + V ++ + I +F+ + V G +V + +
Sbjct: 937 LLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLA 996
Query: 324 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFAN 383
++ +G I V Y ++L + + + + ET+ + +R+F
Sbjct: 997 TPIAAIIIPPLGL-IYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEE 1055
Query: 384 EEE---EAEVYLRKLQQVYK----LNRKEA-----------------AAYMYYVWGSGSV 419
+E ++++ + + Q+ Y NR A A + +G V
Sbjct: 1056 QERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLV 1115
Query: 420 GSVYSGLMQ-----------------GVGAAEKVFEFIDRQ---PTMVHDGSLAPDHLE- 458
G S +Q + A E++ E+ + + P + + + +
Sbjct: 1116 GLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQV 1175
Query: 459 GRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGG 518
GRV+F N YR VL++++ +++ G+ +VG +G+GKSS L G
Sbjct: 1176 GRVEFRNYCLRYR-EDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEG 1234
Query: 519 RVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPF-----EMVVEAA 573
+++DG I+ L I+++ Q+PVLF+ S+ N+ PF E V +
Sbjct: 1235 EIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD------PFSQYSDEEVWTSL 1288
Query: 574 QKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE 633
+ A+ F+ L D E E G LS GQ+Q V +ARAL+R +L+LDEAT+A+D E
Sbjct: 1289 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1348
Query: 634 SEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAK 693
++ LIQ I + TVL IAHRL+T+ ++VLDKG + + G LL Q GL+
Sbjct: 1349 TDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYS 1408
Query: 694 LVQ 696
+ +
Sbjct: 1409 MAK 1411
Score = 40.0 bits (92), Expect = 0.008
Identities = 19/69 (27%), Positives = 42/69 (60%), Gaps = 5/69 (7%)
Query: 628 SALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQ 687
SAL AE + + G++ T +++ H +S + +I+V+ G++ + G++Q+LLA+
Sbjct: 689 SALLAEMD-----KVEGHVAIKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLAR 743
Query: 688 GGLYAKLVQ 696
G +A+ ++
Sbjct: 744 DGAFAEFLR 752
Score = 38.1 bits (87), Expect = 0.029
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 11/97 (11%)
Query: 452 LAPDHLEGR----------VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSG 501
L PD +E R + N TFT+ R L ++FS+ G + A+VG G G
Sbjct: 625 LEPDSIERRPVKDGGGTNSITVRNATFTW-ARSDPPTLNGITFSIPEGALVAVVGQVGCG 683
Query: 502 KSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRV 538
KSS ++ L G V + + + + YL +V
Sbjct: 684 KSSLLSALLAEMDKVEGHVAIKTRILVTHSMSYLPQV 720
>gi|134142340 ATP-binding cassette, sub-family C, member 1 isoform 2
[Homo sapiens]
Length = 1472
Score = 145 bits (367), Expect = 1e-34
Identities = 125/483 (25%), Positives = 223/483 (46%), Gaps = 59/483 (12%)
Query: 265 LFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGV-VVFMFS 323
L S++ SFF+ +G+L++R + + V ++ + I +F+ + V G +V + +
Sbjct: 993 LLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLA 1052
Query: 324 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFAN 383
++ +G I V Y ++L + + + + ET+ + +R+F
Sbjct: 1053 TPIAAIIIPPLGL-IYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEE 1111
Query: 384 EEE---EAEVYLRKLQQVYK----LNRKEA-----------------AAYMYYVWGSGSV 419
+E ++++ + + Q+ Y NR A A + +G V
Sbjct: 1112 QERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLV 1171
Query: 420 GSVYSGLMQ-----------------GVGAAEKVFEFIDRQ---PTMVHDGSLAPDHLE- 458
G S +Q + A E++ E+ + + P + + + +
Sbjct: 1172 GLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQV 1231
Query: 459 GRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGG 518
GRV+F N YR VL++++ +++ G+ +VG +G+GKSS L G
Sbjct: 1232 GRVEFRNYCLRYR-EDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEG 1290
Query: 519 RVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPF-----EMVVEAA 573
+++DG I+ L I+++ Q+PVLF+ S+ N+ PF E V +
Sbjct: 1291 EIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD------PFSQYSDEEVWTSL 1344
Query: 574 QKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE 633
+ A+ F+ L D E E G LS GQ+Q V +ARAL+R +L+LDEAT+A+D E
Sbjct: 1345 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1404
Query: 634 SEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAK 693
++ LIQ I + TVL IAHRL+T+ ++VLDKG + + G LL Q GL+
Sbjct: 1405 TDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYS 1464
Query: 694 LVQ 696
+ +
Sbjct: 1465 MAK 1467
Score = 74.3 bits (181), Expect = 4e-13
Identities = 36/104 (34%), Positives = 67/104 (64%), Gaps = 3/104 (2%)
Query: 596 KGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEYLIQQAI--HGNLQKHTVL 652
KG LSGGQKQRV++ARA+ N + + D+ SA+DA +++ + I G L+ T +
Sbjct: 705 KGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRI 764
Query: 653 IIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQ 696
++ H +S + +I+V+ G++ + G++Q+LLA+ G +A+ ++
Sbjct: 765 LVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLR 808
Score = 37.0 bits (84), Expect = 0.064
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 11/87 (12%)
Query: 452 LAPDHLEGR----------VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSG 501
L PD +E R + N TFT+ R L ++FS+ G + A+VG G G
Sbjct: 625 LEPDSIERRPVKDGGGTNSITVRNATFTW-ARSDPPTLNGITFSIPEGALVAVVGQVGCG 683
Query: 502 KSSCVNILENFYPLEGGRVLLDGKPIS 528
KSS ++ L G V + G +S
Sbjct: 684 KSSLLSALLAEMDKVEGHVAIKGVNLS 710
>gi|134142337 ATP-binding cassette, sub-family C, member 1 isoform 1
[Homo sapiens]
Length = 1531
Score = 145 bits (367), Expect = 1e-34
Identities = 125/483 (25%), Positives = 223/483 (46%), Gaps = 59/483 (12%)
Query: 265 LFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGV-VVFMFS 323
L S++ SFF+ +G+L++R + + V ++ + I +F+ + V G +V + +
Sbjct: 1052 LLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLA 1111
Query: 324 LSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFAN 383
++ +G I V Y ++L + + + + ET+ + +R+F
Sbjct: 1112 TPIAAIIIPPLGL-IYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEE 1170
Query: 384 EEE---EAEVYLRKLQQVYK----LNRKEA-----------------AAYMYYVWGSGSV 419
+E ++++ + + Q+ Y NR A A + +G V
Sbjct: 1171 QERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLV 1230
Query: 420 GSVYSGLMQ-----------------GVGAAEKVFEFIDRQ---PTMVHDGSLAPDHLE- 458
G S +Q + A E++ E+ + + P + + + +
Sbjct: 1231 GLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQV 1290
Query: 459 GRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGG 518
GRV+F N YR VL++++ +++ G+ +VG +G+GKSS L G
Sbjct: 1291 GRVEFRNYCLRYR-EDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEG 1349
Query: 519 RVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPF-----EMVVEAA 573
+++DG I+ L I+++ Q+PVLF+ S+ N+ PF E V +
Sbjct: 1350 EIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLD------PFSQYSDEEVWTSL 1403
Query: 574 QKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE 633
+ A+ F+ L D E E G LS GQ+Q V +ARAL+R +L+LDEAT+A+D E
Sbjct: 1404 ELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLE 1463
Query: 634 SEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAK 693
++ LIQ I + TVL IAHRL+T+ ++VLDKG + + G LL Q GL+
Sbjct: 1464 TDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYS 1523
Query: 694 LVQ 696
+ +
Sbjct: 1524 MAK 1526
Score = 107 bits (266), Expect = 5e-23
Identities = 77/260 (29%), Positives = 130/260 (50%), Gaps = 32/260 (12%)
Query: 452 LAPDHLEGR----------VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSG 501
L PD +E R + N TFT+ R L ++FS+ G + A+VG G G
Sbjct: 625 LEPDSIERRPVKDGGGTNSITVRNATFTW-ARSDPPTLNGITFSIPEGALVAVVGQVGCG 683
Query: 502 KSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYG- 560
KSS ++ L G V + G ++ V Q+ + S+ +NI +G
Sbjct: 684 KSSLLSALLAEMDKVEGHVAIKGS-------------VAYVPQQAWIQNDSLRENILFGC 730
Query: 561 -LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPP 619
L + V++A + L G TE GEKG LSGGQKQRV++ARA+ N
Sbjct: 731 QLEEPYYRSVIQACALLPD---LEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNAD 787
Query: 620 VLILDEATSALDAE-SEYLIQQAI--HGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVV 676
+ + D+ SA+DA +++ + I G L+ T +++ H +S + +I+V+ G++
Sbjct: 788 IYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKIS 847
Query: 677 QQGTHQQLLAQGGLYAKLVQ 696
+ G++Q+LLA+ G +A+ ++
Sbjct: 848 EMGSYQELLARDGAFAEFLR 867
>gi|25914749 ATP-binding cassette, sub-family C, member 10 [Homo
sapiens]
Length = 1464
Score = 144 bits (362), Expect = 4e-34
Identities = 138/528 (26%), Positives = 236/528 (44%), Gaps = 79/528 (14%)
Query: 232 VCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTS 291
+C L FAAG TL R L R L++ T FF+ TG +++R +S
Sbjct: 952 LCTLLRAVLFAAGTLQAAATLH--------RRLLHRVLMAPVT-FFNATPTGRILNRFSS 1002
Query: 292 DTTMVSDLVSQNINVFLRNTVKVTGVVVFMFS-LSWQLSLVTFMGFPIIMMVSNIYGKYY 350
D D + +N+ L N + G++ + S L W L L+ P+ +M ++ ++Y
Sbjct: 1003 DVACADDSLPFILNILLANAAGLLGLLAVLGSGLPWLLLLLP----PLSIMYYHVQ-RHY 1057
Query: 351 KRLSKEVQN----ALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEA 406
+ S+E++ L+ + +T++ + +R+ E LR L+ + +
Sbjct: 1058 RASSRELRRLGSLTLSPLYSHLADTLAGLSVLRATGATYRFEEENLRLLELNQRCQFATS 1117
Query: 407 AAYMYY-----VWGSGSVGSV-------------------------------YSGLMQGV 430
A + + G+ V ++ SGL+
Sbjct: 1118 ATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLSLSYALSLTGLLSGLVSSF 1177
Query: 431 GAAEKVFEFIDR--------------QPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHT 476
E + ++R QP + G L +G V+F++V YR
Sbjct: 1178 TQTEAMLVSVERLEEYTCDLPQEPQGQPLQLGTGWLT----QGGVEFQDVVLAYRPGL-P 1232
Query: 477 QVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLH 536
L V+F + PG+ +VG +GSGKSS + +L GRVLLDG S + L
Sbjct: 1233 NALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAQLR 1292
Query: 537 RVISLVSQEPVLFARSITDNIS-YGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGE 595
++++ QEP LF+ ++ +N+ GL + + A K ++ G E GE
Sbjct: 1293 SQLAIIPQEPFLFSGTVRENLDPQGLHK---DRALWQALKQCHLSEVITSMGGLDGELGE 1349
Query: 596 KGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIA 655
G LS GQ+Q + +ARAL+ + +L +DEAT+++D +++ L+QQ I TVL IA
Sbjct: 1350 GGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIA 1409
Query: 656 HRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQ-GGLYAKLVQRQMLGL 702
HRL+T+ ++ ++VL GRVV+ + L Q L+ +L+Q G+
Sbjct: 1410 HRLNTILNSDRVLVLQAGRVVELDSPATLRNQPHSLFQQLLQSSQQGV 1457
Score = 91.7 bits (226), Expect = 2e-18
Identities = 60/198 (30%), Positives = 102/198 (51%), Gaps = 12/198 (6%)
Query: 489 GKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVL 548
G + +VG G GKSS + + G V + G L + L +QEP +
Sbjct: 598 GMLVGIVGKVGCGKSSLLAAIAGELHRLRGHVAVRG----------LSKGFGLATQEPWI 647
Query: 549 FARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRV 608
+I DNI +G T ++ E + + + L G TE GEKG LSGGQ+ R+
Sbjct: 648 QFATIRDNILFG-KTFDAQLYKEVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARI 706
Query: 609 AMARALVRNPPVLILDEATSALDAE-SEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLI 667
A+ARA+ + + +LD+ +A+DA+ + +L+ + I G L T L+ HR +E A +
Sbjct: 707 ALARAVYQEKELYLLDDPLAAVDADVANHLLHRCILGMLSYTTRLLCTHRTEYLERADAV 766
Query: 668 VVLDKGRVVQQGTHQQLL 685
++++ GR+++ G ++L
Sbjct: 767 LLMEAGRLIRAGPPSEIL 784
>gi|110832837 ATP-binding cassette, sub-family C, member 9 isoform
SUR2B [Homo sapiens]
Length = 1549
Score = 140 bits (353), Expect = 4e-33
Identities = 139/584 (23%), Positives = 242/584 (41%), Gaps = 90/584 (15%)
Query: 187 FLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQF--STAVVIVCLLAIGSSFAAG 244
+L + FFL++ + L + AID + + + +T G S G
Sbjct: 985 YLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTSEYSINNTGKADQTYYVAGFSILCG 1044
Query: 245 IRGGIFTLIFARLNIR---------LRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTM 295
GIF + L + L + L ++ FFD G +++R ++DT +
Sbjct: 1045 --AGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNI 1102
Query: 296 VSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSK 355
+ + + R+T+ + M S + + LV + + KY++ SK
Sbjct: 1103 IDQHIPPTLESLTRSTLLCLSAIG-MISYATPVFLVALLPLGVAFYFIQ---KYFRVASK 1158
Query: 356 EVQNA--------LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAA 407
++Q L S TAE + T+R+F +E R Q++ +L
Sbjct: 1159 DLQELDDSTQLPLLCHFSETAE----GLTTIRAFRHET-------RFKQRMLELTDTNNI 1207
Query: 408 AYMYY--------------------------VWGSGSVGSVYSGLMQGV----------- 430
AY++ + GS + G V GL+ +
Sbjct: 1208 AYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVR 1267
Query: 431 ---------GAAEKVFEFIDRQPTMVH---DGSLAPDHL--EGRVDFENVTFTYRTRPHT 476
GA +KV F+ + D S P+H EG + ++ Y
Sbjct: 1268 NLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKP 1327
Query: 477 QVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLH 536
VL++V + PG+ + G +GSGKSS + G++++DG IS L
Sbjct: 1328 -VLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLR 1386
Query: 537 RVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEK 596
+S++ Q+P+LF+ SI N+ + + EA + A + L G E
Sbjct: 1387 SRLSIILQDPILFSGSIRFNLDPECKCTD-DRLWEALEIAQLKNMVKSLPGGLDAVVTEG 1445
Query: 597 GAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAH 656
G S GQ+Q +ARA VR +LI+DEAT+++D +E ++Q+ + TV+ IAH
Sbjct: 1446 GENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAH 1505
Query: 657 RLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQ-GGLYAKLVQRQM 699
R+ T+ A L++V+ +G +++ T + LLAQ G++A V+ M
Sbjct: 1506 RVHTILTADLVIVMKRGNILEYDTPESLLAQENGVFASFVRADM 1549
Score = 97.8 bits (242), Expect = 3e-20
Identities = 69/211 (32%), Positives = 114/211 (54%), Gaps = 12/211 (5%)
Query: 479 LQNVSFSLSPGKVTALVGPSGSGKSSCV-NILENFYPLEGG---RVLLDGKPISAYDHKY 534
L N+ + G++T +VG G GKSS + IL LEG + + +P
Sbjct: 688 LSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSR 747
Query: 535 LHRVISLVSQEPVLFARSITDNISYGLP--TVPFEMVVEAAQKANAHGFIMELQDGYSTE 592
++ +Q+P L ++ +NI++G P ++ V +A + I L G TE
Sbjct: 748 NRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDAC---SLQPDIDLLPFGDQTE 804
Query: 593 TGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEYLIQQAIHGNLQ--KH 649
GE+G LSGGQ+QR+ +ARAL +N ++ LD+ SALD S++L+Q+ I LQ K
Sbjct: 805 IGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKR 864
Query: 650 TVLIIAHRLSTVEHAHLIVVLDKGRVVQQGT 680
T++++ H+L + HA I+ + G V+++GT
Sbjct: 865 TLVLVTHKLQYLTHADWIIAMKDGSVLREGT 895
>gi|239756495 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1312
Score = 135 bits (341), Expect = 1e-31
Identities = 137/522 (26%), Positives = 234/522 (44%), Gaps = 69/522 (13%)
Query: 233 CLLAIG--SSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLT 290
CL AIG +S AA + GG AR + L L +V SFF+ G L++R +
Sbjct: 805 CLQAIGLFASMAAVLLGG------ARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFS 858
Query: 291 SDTTMVSDLVSQNINVFLR---NTVKVTGVVVFMFSLSWQLSLVTFM---GFPIIMMVSN 344
+T V + + L ++V+ VV L+ L F+ GF + +VS+
Sbjct: 859 KETDTVDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSS 918
Query: 345 IYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRK 404
+L + + + + ET VR+F + ++ + +++
Sbjct: 919 C------QLRRLESASYSSVCSHMAETFQGSTVVRAFRTQAPFVAQNNARVDESQRISFP 972
Query: 405 EAAAYMYY-----VWGSGSV-----------GSVYSGLMQ-GVGAAEKV---FEFIDRQP 444
A + + G+G V + +GL+ V AA +V +++ R
Sbjct: 973 RLVADRWLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNW 1032
Query: 445 TMVHDGSLAPDHLE-------------------------GRVDFENVTFTYRTRPHTQV- 478
T + + ++ + ++ G+++F++ F R RP +
Sbjct: 1033 TDLENSIVSVERMQDYAWTPKEAPWRLPTCAAQPPWPQGGQIEFQD--FGLRYRPELPLA 1090
Query: 479 LQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRV 538
+Q VSF + G+ +VG +G+GKSS + L G + +DG PI+ L
Sbjct: 1091 VQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSR 1150
Query: 539 ISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGA 598
IS++ Q+P+LF S+ N+ L E + A + + L + ++G
Sbjct: 1151 ISIIPQDPILFPGSLRMNLDL-LQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGE 1209
Query: 599 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRL 658
LS GQKQ + +ARAL+R +LILDEAT+A+D +E +Q + + TVL+IAHRL
Sbjct: 1210 DLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRL 1269
Query: 659 STVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQML 700
+V ++V+DKG+V + G+ QLLAQ GL+ +L Q L
Sbjct: 1270 RSVMDCARVLVMDKGQVAESGSPAQLLAQKGLFYRLAQESGL 1311
Score = 100 bits (248), Expect = 6e-21
Identities = 79/261 (30%), Positives = 131/261 (50%), Gaps = 28/261 (10%)
Query: 461 VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRV 520
+ ++ TF + ++ L ++ ++ G + A+VGP G+GKSS ++ L G V
Sbjct: 438 ITIQSATFAW-SQESPPCLHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGELSKVEGFV 496
Query: 521 LLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVP--FEMVVEA-AQKAN 577
++G ++ V QE + S+ +N+ +G P E V+EA A + +
Sbjct: 497 SIEG-------------AVAYVPQEAWVQNTSVVENVCFGQELDPPWLERVLEACALQPD 543
Query: 578 AHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEY 636
F +G T GE+G LSGGQKQR+++ARA+ R V +LD+ +ALDA ++
Sbjct: 544 VDSF----PEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLLDDPLAALDAHVGQH 599
Query: 637 LIQQAI--HGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKL 694
+ Q I G LQ T +++ H L + A I+VL G + + G++Q+LL + G L
Sbjct: 600 VFNQVIGPGGLLQGTTRILVTHALHILPQADWIIVLANGAIAEMGSYQELLQRKGALVCL 659
Query: 695 VQRQMLGLQPAADFTAGHNEP 715
+ + QP D G EP
Sbjct: 660 LDQ---ARQP-GDRGEGETEP 676
>gi|190343023 ATP-binding cassette, sub-family C, member 6 isoform 1
[Homo sapiens]
Length = 1503
Score = 135 bits (339), Expect = 2e-31
Identities = 137/522 (26%), Positives = 233/522 (44%), Gaps = 69/522 (13%)
Query: 233 CLLAIG--SSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLT 290
CL AIG +S AA + GG AR + L L +V SFF+ G L++R +
Sbjct: 996 CLQAIGLFASMAAVLLGG------ARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFS 1049
Query: 291 SDTTMVSDLVSQNINVFLR---NTVKVTGVVVFMFSLSWQLSLVTFM---GFPIIMMVSN 344
+T V + + L ++V+ VV L+ L F+ GF + +VS+
Sbjct: 1050 KETDTVDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSS 1109
Query: 345 IYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRK 404
+L + + + + ET VR+F + ++ + +++
Sbjct: 1110 C------QLRRLESASYSSVCSHMAETFQGSTVVRAFRTQAPFVAQNNARVDESQRISFP 1163
Query: 405 EAAAYMYY-----VWGSGSV-----------GSVYSGLMQ-GVGAAEKV---FEFIDRQP 444
A + + G+G V + +GL+ V AA +V +++ R
Sbjct: 1164 RLVADRWLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNW 1223
Query: 445 TMVHDGSLAPDHLE-------------------------GRVDFENVTFTYRTRPHTQV- 478
T + + ++ + ++ G+++F + F R RP +
Sbjct: 1224 TDLENSIVSVERMQDYAWTPKEAPWRLPTCAAQPPWPQGGQIEFRD--FGLRYRPELPLA 1281
Query: 479 LQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRV 538
+Q VSF + G+ +VG +G+GKSS + L G + +DG PI+ L
Sbjct: 1282 VQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSR 1341
Query: 539 ISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGA 598
IS++ Q+P+LF S+ N+ L E + A + + L + ++G
Sbjct: 1342 ISIIPQDPILFPGSLRMNLDL-LQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGE 1400
Query: 599 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRL 658
LS GQKQ + +ARAL+R +LILDEAT+A+D +E +Q + + TVL+IAHRL
Sbjct: 1401 DLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRL 1460
Query: 659 STVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQML 700
+V ++V+DKG+V + G+ QLLAQ GL+ +L Q L
Sbjct: 1461 RSVMDCARVLVMDKGQVAESGSPAQLLAQKGLFYRLAQESGL 1502
Score = 99.4 bits (246), Expect = 1e-20
Identities = 79/261 (30%), Positives = 130/261 (49%), Gaps = 28/261 (10%)
Query: 461 VDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRV 520
+ + TF + ++ L ++ ++ G + A+VGP G+GKSS ++ L G V
Sbjct: 629 ITIHSATFAW-SQESPPCLHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGELSKVEGFV 687
Query: 521 LLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVP--FEMVVEA-AQKAN 577
++G ++ V QE + S+ +N+ +G P E V+EA A + +
Sbjct: 688 SIEG-------------AVAYVPQEAWVQNTSVVENVCFGQELDPPWLERVLEACALQPD 734
Query: 578 AHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEY 636
F +G T GE+G LSGGQKQR+++ARA+ R V +LD+ +ALDA ++
Sbjct: 735 VDSF----PEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLLDDPLAALDAHVGQH 790
Query: 637 LIQQAI--HGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKL 694
+ Q I G LQ T +++ H L + A I+VL G + + G++Q+LL + G L
Sbjct: 791 VFNQVIGPGGLLQGTTRILVTHALHILPQADWIIVLANGAIAEMGSYQELLQRKGALVCL 850
Query: 695 VQRQMLGLQPAADFTAGHNEP 715
+ + QP D G EP
Sbjct: 851 LDQ---ARQP-GDRGEGETEP 867
>gi|110832839 ATP-binding cassette, sub-family C, member 9 isoform
SUR2A-delta-14 [Homo sapiens]
Length = 1513
Score = 134 bits (337), Expect = 3e-31
Identities = 139/580 (23%), Positives = 240/580 (41%), Gaps = 90/580 (15%)
Query: 187 FLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQF--STAVVIVCLLAIGSSFAAG 244
+L + FFL++ + L + AID + + + +T G S G
Sbjct: 949 YLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTSEYSINNTGKADQTYYVAGFSILCG 1008
Query: 245 IRGGIFTLIFARLNIR---------LRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTM 295
GIF + L + L + L ++ FFD G +++R ++DT +
Sbjct: 1009 --AGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNI 1066
Query: 296 VSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSK 355
+ + + R+T+ + M S + + LV + + KY++ SK
Sbjct: 1067 IDQHIPPTLESLTRSTLLCLSAIG-MISYATPVFLVALLPLGVAFYFIQ---KYFRVASK 1122
Query: 356 EVQNA--------LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAA 407
++Q L S TAE + T+R+F +E R Q++ +L
Sbjct: 1123 DLQELDDSTQLPLLCHFSETAE----GLTTIRAFRHET-------RFKQRMLELTDTNNI 1171
Query: 408 AYMYY--------------------------VWGSGSVGSVYSGLMQGV----------- 430
AY++ + GS + G V GL+ +
Sbjct: 1172 AYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVR 1231
Query: 431 ---------GAAEKVFEFIDRQPTMVH---DGSLAPDHL--EGRVDFENVTFTYRTRPHT 476
GA +KV F+ + D S P+H EG + ++ Y
Sbjct: 1232 NLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKP 1291
Query: 477 QVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLH 536
VL++V + PG+ + G +GSGKSS + G++++DG IS L
Sbjct: 1292 -VLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLR 1350
Query: 537 RVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEK 596
+S++ Q+P+LF+ SI N+ + + EA + A + L G E
Sbjct: 1351 SRLSIILQDPILFSGSIRFNLDPECKCTD-DRLWEALEIAQLKNMVKSLPGGLDAVVTEG 1409
Query: 597 GAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAH 656
G S GQ+Q +ARA VR +LI+DEAT+++D +E ++Q+ + TV+ IAH
Sbjct: 1410 GENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAH 1469
Query: 657 RLSTVEHAHLIVVLDKGRVVQQGTHQQLLA-QGGLYAKLV 695
R+S++ A L++V +G +V+ T LLA + GL++ LV
Sbjct: 1470 RVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGLFSTLV 1509
Score = 97.8 bits (242), Expect = 3e-20
Identities = 69/211 (32%), Positives = 114/211 (54%), Gaps = 12/211 (5%)
Query: 479 LQNVSFSLSPGKVTALVGPSGSGKSSCV-NILENFYPLEGG---RVLLDGKPISAYDHKY 534
L N+ + G++T +VG G GKSS + IL LEG + + +P
Sbjct: 652 LSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSR 711
Query: 535 LHRVISLVSQEPVLFARSITDNISYGLP--TVPFEMVVEAAQKANAHGFIMELQDGYSTE 592
++ +Q+P L ++ +NI++G P ++ V +A + I L G TE
Sbjct: 712 NRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDAC---SLQPDIDLLPFGDQTE 768
Query: 593 TGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEYLIQQAIHGNLQ--KH 649
GE+G LSGGQ+QR+ +ARAL +N ++ LD+ SALD S++L+Q+ I LQ K
Sbjct: 769 IGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKR 828
Query: 650 TVLIIAHRLSTVEHAHLIVVLDKGRVVQQGT 680
T++++ H+L + HA I+ + G V+++GT
Sbjct: 829 TLVLVTHKLQYLTHADWIIAMKDGSVLREGT 859
>gi|110832835 ATP-binding cassette, sub-family C, member 9 isoform
SUR2A [Homo sapiens]
Length = 1549
Score = 134 bits (337), Expect = 3e-31
Identities = 139/580 (23%), Positives = 240/580 (41%), Gaps = 90/580 (15%)
Query: 187 FLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQF--STAVVIVCLLAIGSSFAAG 244
+L + FFL++ + L + AID + + + +T G S G
Sbjct: 985 YLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTSEYSINNTGKADQTYYVAGFSILCG 1044
Query: 245 IRGGIFTLIFARLNIR---------LRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTM 295
GIF + L + L + L ++ FFD G +++R ++DT +
Sbjct: 1045 --AGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNI 1102
Query: 296 VSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSK 355
+ + + R+T+ + M S + + LV + + KY++ SK
Sbjct: 1103 IDQHIPPTLESLTRSTLLCLSAIG-MISYATPVFLVALLPLGVAFYFIQ---KYFRVASK 1158
Query: 356 EVQNA--------LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAA 407
++Q L S TAE + T+R+F +E R Q++ +L
Sbjct: 1159 DLQELDDSTQLPLLCHFSETAE----GLTTIRAFRHET-------RFKQRMLELTDTNNI 1207
Query: 408 AYMYY--------------------------VWGSGSVGSVYSGLMQGV----------- 430
AY++ + GS + G V GL+ +
Sbjct: 1208 AYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVR 1267
Query: 431 ---------GAAEKVFEFIDRQPTMVH---DGSLAPDHL--EGRVDFENVTFTYRTRPHT 476
GA +KV F+ + D S P+H EG + ++ Y
Sbjct: 1268 NLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKP 1327
Query: 477 QVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLH 536
VL++V + PG+ + G +GSGKSS + G++++DG IS L
Sbjct: 1328 -VLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLR 1386
Query: 537 RVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEK 596
+S++ Q+P+LF+ SI N+ + + EA + A + L G E
Sbjct: 1387 SRLSIILQDPILFSGSIRFNLDPECKCTD-DRLWEALEIAQLKNMVKSLPGGLDAVVTEG 1445
Query: 597 GAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAH 656
G S GQ+Q +ARA VR +LI+DEAT+++D +E ++Q+ + TV+ IAH
Sbjct: 1446 GENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAH 1505
Query: 657 RLSTVEHAHLIVVLDKGRVVQQGTHQQLLA-QGGLYAKLV 695
R+S++ A L++V +G +V+ T LLA + GL++ LV
Sbjct: 1506 RVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGLFSTLV 1545
Score = 97.8 bits (242), Expect = 3e-20
Identities = 69/211 (32%), Positives = 114/211 (54%), Gaps = 12/211 (5%)
Query: 479 LQNVSFSLSPGKVTALVGPSGSGKSSCV-NILENFYPLEGG---RVLLDGKPISAYDHKY 534
L N+ + G++T +VG G GKSS + IL LEG + + +P
Sbjct: 688 LSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSR 747
Query: 535 LHRVISLVSQEPVLFARSITDNISYGLP--TVPFEMVVEAAQKANAHGFIMELQDGYSTE 592
++ +Q+P L ++ +NI++G P ++ V +A + I L G TE
Sbjct: 748 NRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDAC---SLQPDIDLLPFGDQTE 804
Query: 593 TGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEYLIQQAIHGNLQ--KH 649
GE+G LSGGQ+QR+ +ARAL +N ++ LD+ SALD S++L+Q+ I LQ K
Sbjct: 805 IGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKR 864
Query: 650 TVLIIAHRLSTVEHAHLIVVLDKGRVVQQGT 680
T++++ H+L + HA I+ + G V+++GT
Sbjct: 865 TLVLVTHKLQYLTHADWIIAMKDGSVLREGT 895
>gi|157502201 ATP-binding cassette, sub-family C, member 4 isoform 1
[Homo sapiens]
Length = 1325
Score = 134 bits (336), Expect = 4e-31
Identities = 136/508 (26%), Positives = 234/508 (46%), Gaps = 78/508 (15%)
Query: 261 LRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVF 320
L N +F S++ FFD N G +++R + D + DL+ F++ ++V GVV
Sbjct: 797 LHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVV-- 854
Query: 321 MFSLSWQLSLVTFMGFPIIMM--VSNIYGKYYKRLSKEVQNALARASNTA----EETISA 374
S ++++ ++ P++ + + +Y+ S++V+ + + ++
Sbjct: 855 ----SVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQG 910
Query: 375 MKTVRSFANEEEEAEVY------------LRKLQQVYKLNRKEAAAYMYYV---WGS--- 416
+ T+R++ EE E++ L + R +A M+ + +GS
Sbjct: 911 LWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLIL 970
Query: 417 ------GSVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFEN-VTFT 469
G VG S + +G +F++ RQ V + ++ + + D E +
Sbjct: 971 AKTLDAGQVGLALSYALTLMG----MFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWE 1026
Query: 470 YRTRP-----HTQVL--QNVSFSLSPG------KVTAL---------VGPSGSGKSSCVN 507
Y+ RP H V+ NV+F SPG +TAL VG +G+GKSS ++
Sbjct: 1027 YQKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLIS 1086
Query: 508 ILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPF- 566
L EG ++ +D + L + +S++ QEPVLF ++ N+ PF
Sbjct: 1087 ALFRLSEPEG-KIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLD------PFN 1139
Query: 567 ----EMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLI 622
E + A Q+ I +L TE E G+ S GQ+Q V +ARA++R +LI
Sbjct: 1140 EHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILI 1199
Query: 623 LDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQ 682
+DEAT+ +D ++ LIQ+ I TVL IAHRL+T+ + I+VLD GR+ +
Sbjct: 1200 IDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPY 1259
Query: 683 QLLA-QGGLYAKLVQRQMLGLQPAADFT 709
LL + L+ K+VQ+ LG AA T
Sbjct: 1260 VLLQNKESLFYKMVQQ--LGKAEAAALT 1285
Score = 117 bits (293), Expect = 4e-26
Identities = 133/566 (23%), Positives = 247/566 (43%), Gaps = 77/566 (13%)
Query: 186 AFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQ--FSTAVVIVCLLAIGSSFAA 243
++LV F LI + + P + G+ I+ MD +TA +L + A
Sbjct: 91 SYLVLGIFTLIEES-AKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILA 149
Query: 244 GIRGGIFTLIFA---RLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 300
+ F + RL + + + ++R + + TG +++ L++D
Sbjct: 150 ILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQ-- 207
Query: 301 SQNINVFLRNTVKVTGVVVFMFSLSWQ---LSLVTFMGFPIIMM-VSNIYGKYYKRLSKE 356
+ VFL + + +L W +S + M II++ + + +GK + L +
Sbjct: 208 ---VTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSK 264
Query: 357 VQNALARASNTAEETISAMKTVRSFANEEEEAEVY--LRKLQQVYKLNRKEAAAYM---- 410
T E I+ ++ ++ +A E+ + + LRK +++ K+ R M
Sbjct: 265 TATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRK-KEISKILRSSCLRGMNLAS 323
Query: 411 ---------------YYVWGSGSVGS-------VYSGLMQGV-----GAAEKVFEFIDR- 442
Y + GS S +Y + V A E+V E I
Sbjct: 324 FFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSI 383
Query: 443 ---QPTMVHD-----GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTAL 494
Q ++ D P + V ++ T + T LQ +SF++ PG++ A+
Sbjct: 384 RRIQTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAV 443
Query: 495 VGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSIT 554
VGP G+GKSS ++ + G V + G+ I+ VSQ+P +F+ ++
Sbjct: 444 VGPVGAGKSSLLSAVLGELAPSHGLVSVHGR-------------IAYVSQQPWVFSGTLR 490
Query: 555 DNISYG--LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMAR 612
NI +G +E V++A + L+DG T G++G LSGGQK RV +AR
Sbjct: 491 SNILFGKKYEKERYEKVIKACALKKD---LQLLEDGDLTVIGDRGTTLSGGQKARVNLAR 547
Query: 613 ALVRNPPVLILDEATSALDAE-SEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLD 671
A+ ++ + +LD+ SA+DAE S +L + I L + +++ H+L ++ A I++L
Sbjct: 548 AVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILK 607
Query: 672 KGRVVQQGTHQQLLAQGGLYAKLVQR 697
G++VQ+GT+ + L G + L+++
Sbjct: 608 DGKMVQKGTYTEFLKSGIDFGSLLKK 633
>gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform 1
[Homo sapiens]
Length = 1527
Score = 131 bits (330), Expect = 2e-30
Identities = 123/520 (23%), Positives = 222/520 (42%), Gaps = 75/520 (14%)
Query: 235 LAIGSSFAAGIRGGIFTLIFARLNIR--------LRNCLFRSLVSQETSFFDENRTGDLI 286
L +G A GI G ++ A L L + + SFFD +G ++
Sbjct: 1010 LRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRIL 1069
Query: 287 SRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIY 346
+ + D +V ++++ I + L + +V + + + ++V + +V Y
Sbjct: 1070 NCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFY 1129
Query: 347 GKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEA 406
++L + + + + ET++ +R++ N + E+ K++ +
Sbjct: 1130 AATSRQLKRLESVSRSPIYSHFSETVTGASVIRAY-NRSRDFEIISDT-----KVDANQR 1183
Query: 407 AAYMYYV---WGS---------------------------GSVG---------------- 420
+ Y Y + W S G VG
Sbjct: 1184 SCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWM 1243
Query: 421 -SVYSGLMQGVGAAEKVFEF--IDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQ 477
+ S L + A E+V E+ + + V +GS P+ R + E ++ R RP
Sbjct: 1244 IRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLD 1303
Query: 478 -VLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLH 536
VL+++S + G+ +VG +G+GKSS L G + +DG ++ L
Sbjct: 1304 LVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLR 1363
Query: 537 RVISLVSQEPVLFARSITDNISYGLPTVPFEMVVE-----AAQKANAHGFIMELQDGYST 591
++++ Q+P+LF+ ++ N+ PF E A + ++ H F+ G
Sbjct: 1364 SQLTIIPQDPILFSGTLRMNLD------PFGSYSEEDIWWALELSHLHTFVSSQPAGLDF 1417
Query: 592 ETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTV 651
+ E G LS GQ+Q V +ARAL+R +L+LDEAT+A+D E++ LIQ I TV
Sbjct: 1418 QCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTV 1477
Query: 652 LIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLY 691
L IAHRL+T+ ++VLDKG V + + L+A G++
Sbjct: 1478 LTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIAARGIF 1517
Score = 92.0 bits (227), Expect = 2e-18
Identities = 73/280 (26%), Positives = 136/280 (48%), Gaps = 28/280 (10%)
Query: 424 SGLMQGVGAAEKVFEFIDRQ---PTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQ 480
S L Q + +++ +F+ ++ P V +++P + + + TFT+ + L
Sbjct: 590 SNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGYA---ITIHSGTFTW-AQDLPPTLH 645
Query: 481 NVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVIS 540
++ + G + A+VGP G GKSS V+ L G+V + G ++
Sbjct: 646 SLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGS-------------VA 692
Query: 541 LVSQEPVLFARSITDNISYGLPTVP--FEMVVEAAQKANAHGFIMELQDGYSTETGEKGA 598
V Q+ + ++ +N+ +G P ++ +EA + L G TE GEKG
Sbjct: 693 YVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALL---ADLEMLPGGDQTEIGEKGI 749
Query: 599 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAE-SEYLIQQAI--HGNLQKHTVLIIA 655
LSGGQ+QRV++ARA+ + + +LD+ SA+D+ ++++ I G L T +++
Sbjct: 750 NLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVT 809
Query: 656 HRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLV 695
H +S + I+VL G+V + G + LL + G +A +
Sbjct: 810 HGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFL 849
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,054,819
Number of Sequences: 37866
Number of extensions: 1060511
Number of successful extensions: 3792
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 3446
Number of HSP's gapped (non-prelim): 243
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.