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Search of human proteins with 94538345
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94538345 keratin 35 [Homo sapiens]
(455 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94538345 keratin 35 [Homo sapiens] 910 0.0
gi|4504927 keratin 36 [Homo sapiens] 599 e-171
gi|116488398 keratin 32 [Homo sapiens] 565 e-161
gi|14917115 keratin 31 [Homo sapiens] 562 e-160
gi|14917117 keratin 33A [Homo sapiens] 542 e-154
gi|14917119 keratin 34 [Homo sapiens] 534 e-152
gi|10337581 type I hair keratin 3B [Homo sapiens] 530 e-151
gi|125490370 type I hair keratin KA36 [Homo sapiens] 495 e-140
gi|148277620 type I hair keratin KA35 [Homo sapiens] 462 e-130
gi|15431318 keratin 38 [Homo sapiens] 457 e-128
gi|55770882 keratin 37 [Homo sapiens] 442 e-124
gi|15431310 keratin 14 [Homo sapiens] 411 e-115
gi|4557701 keratin 17 [Homo sapiens] 407 e-114
gi|24430192 keratin 16 [Homo sapiens] 402 e-112
gi|24430190 keratin 15 [Homo sapiens] 384 e-107
gi|24234699 keratin 19 [Homo sapiens] 381 e-106
gi|131412225 keratin 13 isoform a [Homo sapiens] 378 e-105
gi|131412228 keratin 13 isoform b [Homo sapiens] 375 e-104
gi|195972866 keratin 10 [Homo sapiens] 355 6e-98
gi|4557699 keratin 12 [Homo sapiens] 348 8e-96
gi|27894337 keratin 20 [Homo sapiens] 333 1e-91
gi|192807292 keratin 24 [Homo sapiens] 327 1e-89
gi|153945736 keratin 27 [Homo sapiens] 322 4e-88
gi|114431246 keratin 25D [Homo sapiens] 320 1e-87
gi|31559829 keratin 25 [Homo sapiens] 308 9e-84
gi|55956899 keratin 9 [Homo sapiens] 300 2e-81
gi|40354195 keratin 18 [Homo sapiens] 299 4e-81
gi|4557888 keratin 18 [Homo sapiens] 299 4e-81
gi|27894339 keratin 23 [Homo sapiens] 289 4e-78
gi|31559815 keratin 26 [Homo sapiens] 286 2e-77
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 910 bits (2351), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 1 MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSS 60
MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSS
Sbjct: 1 MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSS 60
Query: 61 YRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQ 120
YRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQ
Sbjct: 61 YRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQ 120
Query: 121 ENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAAD 180
ENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAAD
Sbjct: 121 ENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAAD 180
Query: 181 DFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVN 240
DFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVN
Sbjct: 181 DFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVN 240
Query: 241 SLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVV 300
SLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVV
Sbjct: 241 SLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVV 300
Query: 301 SSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMIT 360
SSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMIT
Sbjct: 301 SSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMIT 360
Query: 361 NVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYSPS 420
NVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYSPS
Sbjct: 361 NVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYSPS 420
Query: 421 KSCLPCLPAASCGPSAARTNCSPRPICVPCPGGRF 455
KSCLPCLPAASCGPSAARTNCSPRPICVPCPGGRF
Sbjct: 421 KSCLPCLPAASCGPSAARTNCSPRPICVPCPGGRF 455
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 599 bits (1545), Expect = e-171
Identities = 310/440 (70%), Positives = 358/440 (81%), Gaps = 9/440 (2%)
Query: 1 MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSS 60
MA++ FS+GS+K G +GG +RVS++ S SC++PSL+ A S+ GL
Sbjct: 1 MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLG 60
Query: 61 YRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQ 120
SCLP L + + + G GGWF EG G+EKETMQ LNDRLA YLEKVRQLE+
Sbjct: 61 ----SCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLER 116
Query: 121 ENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAAD 180
ENA LESRI+EW E Q+PY+CPDYQSYF+TIE+ Q+K L +K+ENARLV++IDNAKLAAD
Sbjct: 117 ENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAAD 176
Query: 181 DFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVN 240
DFRTKYETE+SLRQLVE+DINGLRRILD+LTLCK+DLEAQVESLKEEL+CLKKNHEEEV+
Sbjct: 177 DFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVS 236
Query: 241 SLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVV 300
LRCQLGDRLNVEVDAAPPVDLN++LE+MRCQYE LVENNRRD E W +TQ+EELNQQVV
Sbjct: 237 VLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVV 296
Query: 301 SSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMIT 360
SSSEQLQ CQ EIIELRRTVNALEIELQAQHSMR++LESTLAETEARYSSQLAQMQC+I+
Sbjct: 297 SSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLIS 356
Query: 361 NVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYS-- 418
NVEAQL+EIR DLERQNQEYQVLLDV+ARLE EI TYR LLE ED KLP PCA
Sbjct: 357 NVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPV 416
Query: 419 ---PSKSCLPCLPAASCGPS 435
PS +PC+P+ C P+
Sbjct: 417 IRVPSVPPVPCVPSVPCTPA 436
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 565 bits (1456), Expect = e-161
Identities = 309/464 (66%), Positives = 350/464 (75%), Gaps = 25/464 (5%)
Query: 1 MASKCLKAGFSSGSLKS-PGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRS 59
M S C SLKS P AS S+ V+ C P+A S C +
Sbjct: 1 MTSSCCVTNNLQASLKSCPRPASVCSSGVNCR--PELCLGYVCQPMACLPSVCLP----T 54
Query: 60 SYRATSCLP-----ALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEK 114
++R SCL + C A G + S G G W+ EG GNEKETMQ LNDRLA YL +
Sbjct: 55 TFRPASCLSKTYLSSSCQAASGISGSM-GPGSWYSEGAFNGNEKETMQFLNDRLASYLTR 113
Query: 115 VRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDN 174
VRQLEQENA LESRI+E QV M PDYQS+FRTIEELQ+K LC+KAENAR+VV IDN
Sbjct: 114 VRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDN 173
Query: 175 AKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKN 234
AKLAADDFR KYE E+++RQLVE+DINGLRRILDDLTLCK+DLEAQVESLKEEL+CLKKN
Sbjct: 174 AKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKN 233
Query: 235 HEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEE 294
HEEEV SLRCQLGDRLN+EVDAAPPVDL RVLEEMRCQYE +VE NRRD E+W + Q EE
Sbjct: 234 HEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEE 293
Query: 295 LNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQ 354
LNQQV +SSEQLQ+ Q++II+LRRTVN LEIELQAQHS+RD+LE+TL E+EARYSSQLAQ
Sbjct: 294 LNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQ 353
Query: 355 MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCA 414
MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLE EINTYR LLE+ED KLPCNPC+
Sbjct: 354 MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCS 413
Query: 415 PDYSPSKSCLPCLPAASCGPSAARTNCSPRPI---CVPCPGGRF 455
+ SC C+P+ P RT C PR + C PCP GR+
Sbjct: 414 -----TPSCTTCVPS----PCVPRTVCVPRTVGMPCSPCPQGRY 448
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 562 bits (1449), Expect = e-160
Identities = 292/399 (73%), Positives = 327/399 (81%), Gaps = 6/399 (1%)
Query: 58 RSSYRATSCLPALC----LPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLE 113
R+S + C+P C LP + WF EG G+EKETMQ LNDRLA YLE
Sbjct: 13 RTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLE 72
Query: 114 KVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEID 173
KVRQLE++NA LE+ IRE +QQ P +CP YQSYF+TIEELQ+K LC+K+ENARLVV+ID
Sbjct: 73 KVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQID 132
Query: 174 NAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKK 233
NAKLAADDFRTKY+TE+SLRQLVESDINGLRRILD+LTLCKSDLEAQVESLKEELLCLK
Sbjct: 133 NAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKS 192
Query: 234 NHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSE 293
NHE+EVN+LRCQLGDRLNVEVDAAP VDLNRVL E R QYE LVE NRR+ E W TQ+E
Sbjct: 193 NHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTE 252
Query: 294 ELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLA 353
ELN+QVVSSSEQLQS QAEIIELRRTVNALEIELQAQH++RD+LE+TL E+EARYSSQL+
Sbjct: 253 ELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLS 312
Query: 354 QMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPC 413
Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRARLECEINTYR LLESED LP NPC
Sbjct: 313 QVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPC 372
Query: 414 APDYSPSKSCLPCL--PAASCGPSAARTNCSPRPICVPC 450
A + SK PCL P SC P A T C+PRP C PC
Sbjct: 373 ATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPC 411
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 542 bits (1397), Expect = e-154
Identities = 290/414 (70%), Positives = 327/414 (78%), Gaps = 21/414 (5%)
Query: 34 SSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALC----LPAGGFATSYSGGGGWFG 89
S SC LPSLS C R+S + C+P C LP + WF
Sbjct: 2 SYSCGLPSLS--------C-----RTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFC 48
Query: 90 EGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFR 149
EG G+EKETMQ LNDRLA YLEKVRQLE++NA LE+ IRE +QQ P +C YQSYF+
Sbjct: 49 EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFK 108
Query: 150 TIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDD 209
TIEELQ+K LCSK+ENARLVV+IDNAKLA+DDFRTKYETE+SLRQLVESDINGLRRILD+
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168
Query: 210 LTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEM 269
LTLC+SDLEAQVESLKEELLCLK+NHE+EVN+LRCQLGDRLNVEVDAAP VDLN+VL E
Sbjct: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228
Query: 270 RCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQA 329
R QYE LVE NRR+ E W TQ+EELN+QVVSSSEQLQS QAEIIELRRTVNALEIELQA
Sbjct: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
Query: 330 QHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRAR 389
QH++RD+LE+TL E+EARYSSQL+Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRAR
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
Query: 390 LECEINTYRGLLESEDSKLPCNPCAPDYSPSKSCLPCLPAASCGPSAARTNCSP 443
LECEINTYR LLESED KLP NPCA + KS PC+ P R C P
Sbjct: 349 LECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCI----SNPCGLRARCGP 398
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 534 bits (1375), Expect = e-152
Identities = 276/384 (71%), Positives = 313/384 (81%), Gaps = 5/384 (1%)
Query: 48 SFSACSVGLG-RSSYRATSCLPALC----LPAGGFATSYSGGGGWFGEGILTGNEKETMQ 102
S+S C LG R+S + C+P C LP + WF EG G+EKETMQ
Sbjct: 44 SYSCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQ 103
Query: 103 SLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSK 162
LNDRLA YLEKVRQLE++NA LE I+E +QQ P +CP YQSYF+TIEELQ+K LC+K
Sbjct: 104 FLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCAK 163
Query: 163 AENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVE 222
AENARLVV IDNAKLA+DDFR+KY+TE SLR LVESDIN +RRILD+LTLCKSDLE+QVE
Sbjct: 164 AENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQVE 223
Query: 223 SLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRR 282
SL+EEL+CLKKNHEEEVN+LR QLGDRLNVEVD AP VDLN+VL E R QYE LVE NRR
Sbjct: 224 SLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINRR 283
Query: 283 DAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLA 342
+ E W TQ+EELN+QVVSSSEQLQSCQAEIIELRRTVNALEIELQAQH++RD+LE+TL
Sbjct: 284 EVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTLT 343
Query: 343 ETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLE 402
E+EA YSSQL+Q+Q +ITNVE+QLAEIR DLERQNQEYQVLLDVRARLECEINTYR LLE
Sbjct: 344 ESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLLE 403
Query: 403 SEDSKLPCNPCAPDYSPSKSCLPC 426
SED KLPCNPCA + SC PC
Sbjct: 404 SEDCKLPCNPCATTNASGNSCGPC 427
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 530 bits (1366), Expect = e-151
Identities = 279/386 (72%), Positives = 317/386 (82%), Gaps = 9/386 (2%)
Query: 58 RSSYRATSCLPALC----LPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLE 113
R+S + C+P C LP + WF EG G+EKETMQ LNDRLA YLE
Sbjct: 13 RTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLE 72
Query: 114 KVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEID 173
KVRQLE++NA LE+ IRE +QQ P +CP YQSYF+TIEELQ+K LCSK+ENARLVV+ID
Sbjct: 73 KVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQID 132
Query: 174 NAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKK 233
NAKLAADDFRTKY+TE SLRQLVESDIN LRRILD+LTLC+SDLEAQ+ESLKEELL LK+
Sbjct: 133 NAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQ 192
Query: 234 NHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSE 293
NHE+EVN+LRCQLGDRLNVEVDAAP VDLN+VL E R QYE LVE NRR+ E W TQ+E
Sbjct: 193 NHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTE 252
Query: 294 ELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLA 353
ELN+QVVSSSEQLQS QAEIIELRRTVNALEIELQAQH++R +LE+TL E+EARYSSQL+
Sbjct: 253 ELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLS 312
Query: 354 QMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPC 413
Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRARLECEINTYR LLESED KLP NPC
Sbjct: 313 QVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPC 372
Query: 414 APDYS---PSKSCL--PCLPAASCGP 434
A + P SC+ PC P + CGP
Sbjct: 373 ATTNACEKPIGSCVTNPCGPRSRCGP 398
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 495 bits (1275), Expect = e-140
Identities = 259/438 (59%), Positives = 321/438 (73%), Gaps = 20/438 (4%)
Query: 1 MASKCLKAGFSSGSLKSPGG---ASGGSTRVSAM---YSSSSCKLPSLSPVARSFSACSV 54
M S C S S + G AS S + + ++S C+ PS +R + C +
Sbjct: 1 MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLL 60
Query: 55 GLGRSSYRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEK 114
+ + CL C W +G+ T NEKETMQ LNDRLA YLEK
Sbjct: 61 PCYFTGSCNSPCLVGNC--------------AWCEDGVFTSNEKETMQFLNDRLASYLEK 106
Query: 115 VRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDN 174
VR LE+ NA LESRI+E CEQ +P +CPDYQ YF TIE+LQ+K LC+KAEN+RL V++DN
Sbjct: 107 VRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDN 166
Query: 175 AKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKN 234
KLA DDF++KYE+E+SLRQL+E+DI+ L IL++LTLCKSDLEA VESLKE+LLCLKKN
Sbjct: 167 CKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKN 226
Query: 235 HEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEE 294
HEEEVN LR QLGDRL+VE+D AP +DLNRVL+EMRCQ ET++ NNRR+AE+WL Q+EE
Sbjct: 227 HEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEE 286
Query: 295 LNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQ 354
LNQQ +SS+EQLQ CQ EI+EL+RT +ALEIELQAQ S+ ++LE T+AETEA+YSSQLAQ
Sbjct: 287 LNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQ 346
Query: 355 MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCA 414
+QC+I N+E QLAEIR DLERQNQEYQVLLDV+ARLE EINTY GLL+SEDS+L C+PC+
Sbjct: 347 IQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCS 406
Query: 415 PDYSPSKSCLPCLPAASC 432
+ S +C PC C
Sbjct: 407 TTCTSSNTCEPCSAYVIC 424
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 462 bits (1190), Expect = e-130
Identities = 236/368 (64%), Positives = 287/368 (77%), Gaps = 7/368 (1%)
Query: 87 WFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQS 146
W+GEGI NEKETMQ LN+RLA YL+KVR LE+ENA LES+I+E +++P +CPDY S
Sbjct: 87 WYGEGI-NSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLS 145
Query: 147 YFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRI 206
Y+ TIEELQ+K LC+KAEN+RLV +IDN KL ADD R KYE EVSLRQLVESD NGL++I
Sbjct: 146 YYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQI 205
Query: 207 LDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVL 266
L+ LTL K+DLEAQV+SLKEELLCLK NH+EE+NSL+CQLG+RL++EV AAP DLN+VL
Sbjct: 206 LNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVL 265
Query: 267 EEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIE 326
+EMRCQYE ++E NR+D E W +TQ EELNQQVV+SS+Q Q CQ EIIELRR+VN LE+E
Sbjct: 266 QEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVE 325
Query: 327 LQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDV 386
LQAQH MRD+ E L ETEARY++ L Q+Q +I N+EAQLAEIR LERQNQEY++LLDV
Sbjct: 326 LQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDV 385
Query: 387 RARLECEINTYRGLLESEDSKLPCNP----CAPDYSPSKSCLPCLPAASCGPSAARTNCS 442
++RLECEI TYR LLES D K PC P C P SP SC ++ + + CS
Sbjct: 386 KSRLECEITTYRSLLESSDGKRPCYPRATKCEP--SPWTSCKSGAIESTAPACTSSSPCS 443
Query: 443 PRPICVPC 450
+ C C
Sbjct: 444 LKEHCSAC 451
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 457 bits (1175), Expect = e-128
Identities = 252/450 (56%), Positives = 307/450 (68%), Gaps = 39/450 (8%)
Query: 28 VSAMYSSSSCKLP-SLSPVARSFSACSVGLGRSSY------------------------- 61
+++ YSSSSC L +++P AR+ S + +G
Sbjct: 1 MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGST 60
Query: 62 ---RATSCLPALC-----LPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLE 113
R + CLP C LP G G +GE L G+EKETMQ LNDRLA YLE
Sbjct: 61 PLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLE 120
Query: 114 KVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEID 173
KVRQLEQENA LE+ + E + +CPDYQSYF TIEELQ+K LCSKAENARL+V+ID
Sbjct: 121 KVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQID 180
Query: 174 NAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKK 233
NAKLAADDFR K E+E SLRQLVE+D G +++LDD TL K+DLEAQ ESLKEE L LK
Sbjct: 181 NAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
Query: 234 NHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSE 293
NHE+EV LR QLG++L +E+D P +DLNRVL EMR QYE ++E NR+D E W QSE
Sbjct: 241 NHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSE 300
Query: 294 ELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLA 353
++ Q +S SE+LQ CQ+EI+ELR TVNALE+E QAQH+++D L+++L E E R+ ++LA
Sbjct: 301 GISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELA 360
Query: 354 QMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPC 413
QMQ +I+NVE QL+EIRADLERQNQEYQVLLDV+ RLE EI TYR LLESED KLPCNPC
Sbjct: 361 QMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPC 420
Query: 414 APDYSPSKSCLPCLPAASCGPSAARTNCSP 443
+ SPS PC P SCGP T C P
Sbjct: 421 ST--SPSCVTAPCAPRPSCGPC---TTCGP 445
>gi|55770882 keratin 37 [Homo sapiens]
Length = 449
Score = 442 bits (1137), Expect = e-124
Identities = 245/441 (55%), Positives = 304/441 (68%), Gaps = 41/441 (9%)
Query: 28 VSAMYSSSSCKLP-SLSPVARSFSACSVGLG----RSSYRATSCL--------------- 67
+++ YS+SSC L +++P AR+ + +G + A+ CL
Sbjct: 1 MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGST 60
Query: 68 ----PALCLPAGGFA------TSYSGGG----GWFGEGILTGNEKETMQSLNDRLAGYLE 113
P+LCLP T + G G +G+ L G+EKETM+ LNDRLA YLE
Sbjct: 61 PLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLE 120
Query: 114 KVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEID 173
KVRQLEQENA LE+ + E + +CPDYQSYFRTIEELQ+K LCSKAENARL+V+ID
Sbjct: 121 KVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQID 180
Query: 174 NAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKK 233
NAKLAADDFR K E+E SL QLVE+D G +++LDD TL K+DLEAQ ESLKEE L LK
Sbjct: 181 NAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
Query: 234 NHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSE 293
NHE+EV LR QLG++ +E+D P +DLNRVL EMR QYE +VE N +D E W QSE
Sbjct: 241 NHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSE 300
Query: 294 ELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLA 353
++ Q +S SE+LQ CQ+EI+ELR TVNALE+E QAQH+++D L+++L E E RY ++LA
Sbjct: 301 GISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELA 360
Query: 354 QMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPC 413
QMQ +I+N+E QL+EIRADLERQNQEYQVLLDV+ARLE EI TYR LLESED KLPCNPC
Sbjct: 361 QMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPC 420
Query: 414 APDYSPSKSCLPCLPAASCGP 434
S SC C SCGP
Sbjct: 421 ----STPASCTSC---PSCGP 434
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 411 bits (1056), Expect = e-115
Identities = 227/425 (53%), Positives = 303/425 (71%), Gaps = 23/425 (5%)
Query: 5 CLKAGFSSGSLKSP----GGASGGSTRVSAMYSSSSCKLPS-----LSPVARSFSACSV- 54
C + SS S+K GG GGS+R+S++ + SC+ PS LS + FS+
Sbjct: 4 CSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAY 63
Query: 55 GLGRSSYRATSCLPALCLPAGGFATSYSGG---------GGWF--GEGILTGNEKETMQS 103
GLG S + GF Y GG GG F G+G+L G+EK TMQ+
Sbjct: 64 GLGGGYGGGFSSSSSSF--GSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQN 121
Query: 104 LNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKA 163
LNDRLA YL+KVR LE+ NA LE +IR+W ++Q P DY YF+TIE+L+ K L +
Sbjct: 122 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATV 181
Query: 164 ENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVES 223
+NA ++++IDNA+LAADDFRTKYETE++LR VE+DINGLRR+LD+LTL ++DLE Q+ES
Sbjct: 182 DNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIES 241
Query: 224 LKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRD 283
LKEEL LKKNHEEE+N+LR Q+G +NVE+DAAP VDL+R+L EMR QYE + E NR+D
Sbjct: 242 LKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKD 301
Query: 284 AEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAE 343
AE+W T++EELN++V ++SE +QS ++EI ELRRT+ LEIELQ+Q SM+ +LE++L E
Sbjct: 302 AEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEE 361
Query: 344 TEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLES 403
T+ RY QLAQ+Q MI +VE QLA++R ++E+QNQEY++LLDV+ RLE EI TYR LLE
Sbjct: 362 TKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEG 421
Query: 404 EDSKL 408
ED+ L
Sbjct: 422 EDAHL 426
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 407 bits (1047), Expect = e-114
Identities = 218/402 (54%), Positives = 291/402 (72%), Gaps = 20/402 (4%)
Query: 11 SSGSLKSPGGASGGSTRVSAMYS----SSSCKLPSLSPVARSFSACSVGLGRSSYRATSC 66
SS S+K G GGS+R S S + SC+L S + + LG SSY +
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGST-------LGGSSYSSCYS 62
Query: 67 LPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLE 126
+ GG+ +S+ G +G+L G EK TMQ+LNDRLA YL+KVR LE+ N LE
Sbjct: 63 FGS----GGGYGSSFGGV-----DGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELE 113
Query: 127 SRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKY 186
+IR+W ++Q P DY Y+RTIEELQ K L + +NA ++++IDNA+LAADDFRTK+
Sbjct: 114 VKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKF 173
Query: 187 ETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQL 246
ETE +LR VE+DINGLRR+LD+LTL ++DLE Q+E+LKEEL LKKNHEEE+N+LR Q+
Sbjct: 174 ETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQV 233
Query: 247 GDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQL 306
G +NVE+DAAP VDL+R+L EMR QYE + E NR+DAEDW +++EELN++V ++SE +
Sbjct: 234 GGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELV 293
Query: 307 QSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQL 366
QS ++EI ELRRT+ ALEIELQ+Q SM+ +LE LAETE RY QL+Q+Q +I +VE QL
Sbjct: 294 QSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQL 353
Query: 367 AEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKL 408
A++R ++E+QNQEY++LLDV+ RLE EI TYR LLE ED+ L
Sbjct: 354 AQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL 395
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 402 bits (1034), Expect = e-112
Identities = 220/428 (51%), Positives = 298/428 (69%), Gaps = 27/428 (6%)
Query: 5 CLKAGFSSGSLKSP----GGASGGSTRVSAMYSSSSCKLPS-----LSPVARSFSACSVG 55
C + SS S+K GG GGS+R+S++ + SC+ PS LS +R S + G
Sbjct: 4 CSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACG 63
Query: 56 LGRSSYRATSCLPALCLPAGGFATSYSGG-------------GGWF--GEGILTGNEKET 100
LG S + GF Y GG GG F G+G+L G+EK T
Sbjct: 64 LGGGYGGGFSSSSSF---GSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVT 120
Query: 101 MQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLC 160
MQ+LNDRLA YL+KVR LE+ NA LE +IR+W ++Q P DY YF+TIE+L+ K +
Sbjct: 121 MQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIA 180
Query: 161 SKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQ 220
+ ENA+ +++IDNA+LAADDFRTKYE E++LRQ VE+D+NGLRR+LD+LTL ++DLE Q
Sbjct: 181 ATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQ 240
Query: 221 VESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENN 280
+E LKEEL L+KNHEEE+ +LR Q G +NVE+DAAP VDL+R+L EMR QYE + E N
Sbjct: 241 IEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKN 300
Query: 281 RRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALEST 340
RRDAE W +++EELN++V S+SE +QS ++E+ ELRR + LEIELQ+Q SM+ +LE++
Sbjct: 301 RRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENS 360
Query: 341 LAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGL 400
L ET+ RY QL+Q+Q +I +VE QLA++R ++E+Q+QEYQ+LLDV+ RLE EI TYR L
Sbjct: 361 LEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRL 420
Query: 401 LESEDSKL 408
LE ED+ L
Sbjct: 421 LEGEDAHL 428
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 384 bits (987), Expect = e-107
Identities = 212/405 (52%), Positives = 279/405 (68%), Gaps = 21/405 (5%)
Query: 9 GFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLP 68
GF GSL S GG S + SA + SS S C G G S
Sbjct: 29 GFGGGSL-SGGGGSRSISASSARFVSSG----SGGGYGGGMRVCGFGGGAGS-------- 75
Query: 69 ALCLPAGGFATSYSGG-GGWFGEG---ILTGNEKETMQSLNDRLAGYLEKVRQLEQENAS 124
+ GGF GG GG FG G +L+GNEK TMQ+LNDRLA YL+KVR LE+ NA
Sbjct: 76 ---VFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANAD 132
Query: 125 LESRIREWCEQQVPYMCP-DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFR 183
LE +I +W ++Q P DY YF+TIEEL+ K + + +N+R+++EIDNA+LAADDFR
Sbjct: 133 LEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFR 192
Query: 184 TKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLR 243
KYE E++LRQ VE+DINGLRR+LD+LTL ++DLE Q+E L EEL LKKNHEEE+
Sbjct: 193 LKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFS 252
Query: 244 CQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSS 303
QL ++NVE+DAAP VDL RVL EMR QYE + E NRRD E W +++EELN++V S++
Sbjct: 253 SQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNT 312
Query: 304 EQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVE 363
E +Q+ + EI +LRRT+ LEIELQ+Q SM+ LE++LAETE RY++QL Q+Q +I +E
Sbjct: 313 EMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLE 372
Query: 364 AQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKL 408
AQL+E+R ++E QNQEY++LLD++ RLE EI TYR LLE +D+K+
Sbjct: 373 AQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 381 bits (978), Expect = e-106
Identities = 206/402 (51%), Positives = 279/402 (69%), Gaps = 30/402 (7%)
Query: 12 SGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALC 71
S + S GG GGS R P ++ A S S G G S
Sbjct: 9 SSATSSFGGLGGGSVRFG----------PGVAFRAPSIHGGSGGRGVS------------ 46
Query: 72 LPAGGFATSYSGG--GGWFG------EGILTGNEKETMQSLNDRLAGYLEKVRQLEQENA 123
+ + F +S S G GG +G +G+L GNEK TMQ+LNDRLA YL+KVR LE N
Sbjct: 47 VSSARFVSSSSSGAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANG 106
Query: 124 SLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFR 183
LE +IR+W ++Q P DY Y+ TI++L+ K L + EN+R+V++IDNA+LAADDFR
Sbjct: 107 ELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFR 166
Query: 184 TKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLR 243
TK+ETE +LR VE+DINGLRR+LD+LTL ++DLE Q+E LKEEL LKKNHEEE+++LR
Sbjct: 167 TKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLR 226
Query: 244 CQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSS 303
Q+G +++VEVD+AP DL ++L +MR QYE + E NR+DAE W +++EELN++V +
Sbjct: 227 GQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHT 286
Query: 304 EQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVE 363
EQLQ ++E+ +LRRT+ LEIELQ+Q SM+ ALE TLAETEAR+ +QLA +Q +I+ +E
Sbjct: 287 EQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIE 346
Query: 364 AQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESED 405
AQL ++RAD ERQNQEYQ L+D+++RLE EI TYR LLE ++
Sbjct: 347 AQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 378 bits (970), Expect = e-105
Identities = 205/380 (53%), Positives = 273/380 (71%), Gaps = 9/380 (2%)
Query: 75 GGFATSYSGGGGWFGE---GILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIRE 131
GGF ++GG FG G+LTGNEK TMQ+LNDRLA YLEKVR LE+ NA LE +IR+
Sbjct: 79 GGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRD 138
Query: 132 WCEQQVPYMCP-DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEV 190
W +Q P DY Y++TIEEL+ K L + EN R+++EIDNA+LAADDFR KYE E+
Sbjct: 139 WHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENEL 198
Query: 191 SLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRL 250
+LRQ VE+DINGLRR+LD+LTL K+DLE Q+ESL EEL +KKNHEEE+ Q+ ++
Sbjct: 199 ALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQV 258
Query: 251 NVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQ 310
NVE+DA P +DL RVL EMR QYE + E NRRDAE+W +S ELN++V +++ +Q+ +
Sbjct: 259 NVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSK 318
Query: 311 AEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIR 370
EI ELRRT+ LEIELQ+Q SM+ LE+T+AETE RY+ QL Q+Q +I+++EAQL+E+R
Sbjct: 319 TEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELR 378
Query: 371 ADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNP-CAPDYSPSKSCLPCLPA 429
+++E QNQEY++LLD++ RLE EI TYR LLE +D+K+ P A SP + + +
Sbjct: 379 SEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSS 438
Query: 430 AS----CGPSAARTNCSPRP 445
AS S RT+ RP
Sbjct: 439 ASVTTTSNASGRRTSDVRRP 458
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 375 bits (964), Expect = e-104
Identities = 194/337 (57%), Positives = 257/337 (76%), Gaps = 4/337 (1%)
Query: 75 GGFATSYSGGGGWFGE---GILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIRE 131
GGF ++GG FG G+LTGNEK TMQ+LNDRLA YLEKVR LE+ NA LE +IR+
Sbjct: 79 GGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRD 138
Query: 132 WCEQQVPYMCP-DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEV 190
W +Q P DY Y++TIEEL+ K L + EN R+++EIDNA+LAADDFR KYE E+
Sbjct: 139 WHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENEL 198
Query: 191 SLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRL 250
+LRQ VE+DINGLRR+LD+LTL K+DLE Q+ESL EEL +KKNHEEE+ Q+ ++
Sbjct: 199 ALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQV 258
Query: 251 NVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQ 310
NVE+DA P +DL RVL EMR QYE + E NRRDAE+W +S ELN++V +++ +Q+ +
Sbjct: 259 NVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSK 318
Query: 311 AEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIR 370
EI ELRRT+ LEIELQ+Q SM+ LE+T+AETE RY+ QL Q+Q +I+++EAQL+E+R
Sbjct: 319 TEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELR 378
Query: 371 ADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSK 407
+++E QNQEY++LLD++ RLE EI TYR LLE +D+K
Sbjct: 379 SEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 355 bits (910), Expect = 6e-98
Identities = 208/407 (51%), Positives = 267/407 (65%), Gaps = 25/407 (6%)
Query: 9 GFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVG---LGRSSYRATS 65
G SSG GG GGS R S Y SSS SF S G G S+
Sbjct: 68 GGSSGGYGGLGGFGGGSFRGS--YGSSSFG----GSYGGSFGGGSFGGGSFGGGSFGGGG 121
Query: 66 CLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASL 125
GGF + GG G G G+L+GNEK TMQ+LNDRLA YL+KVR LE+ N L
Sbjct: 122 ------FGGGGFGGGFGGGFGGDG-GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYEL 174
Query: 126 ESRIREWCE------QQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAA 179
E +I+EW E Q P DY Y++TI++L+ + L +NA ++++IDNA+LAA
Sbjct: 175 EGKIKEWYEKHGNSHQGEPR---DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAA 231
Query: 180 DDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEV 239
DDFR KYE EV+LRQ VE+DINGLRR+LD+LTL K+DLE Q+ESL EEL LKKNHEEE+
Sbjct: 232 DDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEM 291
Query: 240 NSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQV 299
LR +NVE++AAP VDL ++L MR QYE L E NR+DAE W + +S+EL ++
Sbjct: 292 KDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEI 351
Query: 300 VSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMI 359
++ EQ+ S ++EI ELRR V ALEIELQ+Q +++ +LE++LAETE RY QL+Q+Q I
Sbjct: 352 DNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQI 411
Query: 360 TNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDS 406
+ +E QL +IRA+ E QN EYQ LLD++ RLE EI TYR LLE E S
Sbjct: 412 SALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGS 458
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 348 bits (892), Expect = 8e-96
Identities = 196/414 (47%), Positives = 275/414 (66%), Gaps = 20/414 (4%)
Query: 1 MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSS 60
M++ + +G+ GS G + GG ++M+ SSS + S A +G G
Sbjct: 33 MSASSVGSGYG-GSAFGFGASCGGGFSAASMFGSSS----GFGGGSGSSMAGGLGAGYGR 87
Query: 61 YRATSCLPALCLPAGGFATSYSGGGGWFG------EGILTGNEKETMQSLNDRLAGYLEK 114
L + GG S GGG G G+L+G+EKETMQ+LNDRLA YL+K
Sbjct: 88 ALGGGSFGGLGMGFGG-----SPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDK 142
Query: 115 VRQLEQENASLESRIREWCEQQ----VPYMCPDYQSYFRTIEELQKKTLCSKAENARLVV 170
VR LE+ N LE++IREW E + DY Y+ IE+L+ K + + NA+L++
Sbjct: 143 VRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLL 202
Query: 171 EIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLC 230
+IDNA+LAA+DFR KYE E++LRQ VE+DINGLRR+LD+LTL ++DLE Q+ESL EEL
Sbjct: 203 QIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAY 262
Query: 231 LKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDT 290
+KKNHE+E+ S R ++VE+DAAP VDL R+L +MR QYET+ E NR+DAE W
Sbjct: 263 MKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIE 322
Query: 291 QSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSS 350
+S EL +++ +++EQLQS ++E+ +LRR LEIELQ+Q +M+ +LE +LAE E Y +
Sbjct: 323 KSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCA 382
Query: 351 QLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESE 404
QL+Q+Q +I+N+EAQL ++RAD ERQN ++Q LL+V+ARLE EI TYR LL+ E
Sbjct: 383 QLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGE 436
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 333 bits (855), Expect = 1e-91
Identities = 169/331 (51%), Positives = 239/331 (72%), Gaps = 5/331 (1%)
Query: 77 FATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQ 136
+ + +GGG F GNEK MQ+LNDRLA YLEKVR LEQ N+ LE +I++W E
Sbjct: 55 YGSDLTGGGDLF-----VGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETN 109
Query: 137 VPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLV 196
P DY +Y+R IEEL+ + ++ +NAR V++IDNAKLAA+DFR KYETE +R V
Sbjct: 110 APRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTV 169
Query: 197 ESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDA 256
E+D+ GL ++ DDLTL K+DLE Q+E L ++L LKK H+EEV+ L LG+ +NVEVDA
Sbjct: 170 EADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDA 229
Query: 257 APPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIEL 316
AP ++L ++ EMR +YE + + N ++A++ + Q+ L QQV ++E+L+ + ++ EL
Sbjct: 230 APGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTEL 289
Query: 317 RRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQ 376
RRT +LEIELQ+ SM+++LE TL ET+ARYSSQLA +Q +++++EAQL +IR+++ERQ
Sbjct: 290 RRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQ 349
Query: 377 NQEYQVLLDVRARLECEINTYRGLLESEDSK 407
N EY +LLD++ RLE EI TYR LLE ED K
Sbjct: 350 NNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 327 bits (838), Expect = 1e-89
Identities = 187/410 (45%), Positives = 260/410 (63%), Gaps = 11/410 (2%)
Query: 2 ASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSY 61
AS C +G SSG+ G GS V + +S SF S G GR S
Sbjct: 47 ASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGASGSGTGFGG-GSSFGGVS-GFGRGSG 104
Query: 62 RATSCLPALCLPAGGFATSYSGG-GGWFGEG-ILTGNEKETMQSLNDRLAGYLEKVRQLE 119
S A G SY GG GG G+G + +G EK+TMQ+LNDRLA YL+KVR LE
Sbjct: 105 FCGSS--RFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALE 162
Query: 120 QENASLESRIREWCEQQVPYMCP-----DYQSYFRTIEELQKKTLCSKAENARLVVEIDN 174
+ N LE++I+EW ++ P DY Y+ IE+L+ + + + ENA +++ IDN
Sbjct: 163 EANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDN 222
Query: 175 AKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKN 234
A+LAADDFR KYE E+ LRQ VE+DINGLR++LDDLT+ +SDLE Q+ES EEL L+KN
Sbjct: 223 ARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKN 282
Query: 235 HEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEE 294
HEEE+ +++ G + VE++AAP DL ++L +MR QYE L E NRR+AE+ + QS
Sbjct: 283 HEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSAS 342
Query: 295 LNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQ 354
L Q+ + + S + EI EL+RT+ ALEIELQ+Q +M+ +LE TLA+TEA Y +QL++
Sbjct: 343 LQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSE 402
Query: 355 MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESE 404
+Q I+ +E ++ +I + + QN EY+ LLD++ RLE EI TYR LL+ E
Sbjct: 403 IQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGE 452
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 322 bits (825), Expect = 4e-88
Identities = 183/410 (44%), Positives = 254/410 (61%), Gaps = 32/410 (7%)
Query: 10 FSSGSLKSPGGASGGSTRVSA----MYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATS 65
FSS S + GS R+S+ + ++C +P + S +C+ G G SS
Sbjct: 5 FSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIG----SGFSCAFG-GSSS----- 54
Query: 66 CLPALCLPAGGFATSYSGGGGWFG------EGILTGNEKETMQSLNDRLAGYLEKVRQLE 119
AGG+ GG G+L+GNEK TMQ+LNDRLA YLE VR LE
Sbjct: 55 --------AGGYGGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALE 106
Query: 120 QENASLESRIREWCEQQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNA 175
+ NA LE +I+ W E+ P C DY YF I+EL+ + + + NA +V++ DNA
Sbjct: 107 EANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNA 166
Query: 176 KLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNH 235
+L ADDFR K+E E++L Q VE+DINGLRR+LD+LTLC++DLE Q+E+L EEL LKKNH
Sbjct: 167 RLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNH 226
Query: 236 EEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEEL 295
EEE+ +L+C G +NVE++AAP VDL +L MR +YE L E NRRDAE W + +S L
Sbjct: 227 EEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASL 286
Query: 296 NQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQM 355
QQ+ + S + E+IE++RT+ LEIELQ+ + + +LE +L ETE+ Y +QLAQ+
Sbjct: 287 QQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQI 346
Query: 356 QCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESED 405
Q I +E QL ++R + E Q EY+ LLD++ LE EI TY L++ ED
Sbjct: 347 QAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 320 bits (821), Expect = 1e-87
Identities = 182/409 (44%), Positives = 254/409 (62%), Gaps = 33/409 (8%)
Query: 5 CLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRAT 64
CL++G +GS++ G +G + SS+C VA S +C++G G S
Sbjct: 13 CLRSG--AGSVRPLNGGAGFA-------GSSACG----GSVAGSEFSCALGGGLGS---- 55
Query: 65 SCLPALCLPAGGFATSYSGGGGWFG-----EGILTGNEKETMQSLNDRLAGYLEKVRQLE 119
+P G A G G G+L+GNEK TMQ+LNDRLA YL+ VR LE
Sbjct: 56 -------VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALE 108
Query: 120 QENASLESRIREWCEQQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNA 175
+ NA LE +I+ W E+ P C DY Y TIE+L+ K + S NA ++++IDNA
Sbjct: 109 EANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNA 168
Query: 176 KLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNH 235
+LAADDFR KYE E++L Q VE+DINGLRR+LD+LTLC++D E Q ESL EE+ LKKNH
Sbjct: 169 RLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNH 228
Query: 236 EEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEEL 295
EEE+ +L+C G +NVE++AAP VDL +L MR +YE L E NR+DAE W + +S L
Sbjct: 229 EEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASL 288
Query: 296 NQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQM 355
QQ+ S ++++ E+RRT+ LEI+LQ+ + + +LE +L ETE+ Y +QLAQ+
Sbjct: 289 QQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQI 348
Query: 356 QCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESE 404
Q I +E QL ++R + E Q EY+ LLDV+ LE EI TY L++ +
Sbjct: 349 QAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD 397
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 308 bits (788), Expect = 9e-84
Identities = 173/399 (43%), Positives = 242/399 (60%), Gaps = 27/399 (6%)
Query: 25 STRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALCLPAGGFATSYSG- 83
S R+S+ S SC P+ + S G G S + GF++++ G
Sbjct: 2 SLRLSSA-SRRSCPRPTTGSLRLYGGGTSFGTGNSC--------GISGIGSGFSSAFGGS 52
Query: 84 --GGGWFG-----------EGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIR 130
GG G G+L+GNEK TMQ+LNDRLA YL+ V LE+ NA LE +I+
Sbjct: 53 SSGGNTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIK 112
Query: 131 EWCEQQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKY 186
W E+ P C DY YF I++L+ + + S NA V++IDNA+L ADDFR KY
Sbjct: 113 GWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKY 172
Query: 187 ETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQL 246
E E++L Q VE+D+NGLRR+LD++TLC++DLE Q E+L EE+ LKKNH+EE+ L+C
Sbjct: 173 ENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAA 232
Query: 247 GDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQL 306
G +NVE++AAP VDL +L MR +YE L E NRRDAE W + +S L QQ+
Sbjct: 233 GGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGAT 292
Query: 307 QSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQL 366
S + E+ E++RT+ LEIELQ+ + + +LE +L ETE+ Y +QLAQ+Q I +E QL
Sbjct: 293 TSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQL 352
Query: 367 AEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESED 405
++R + E Q EY+ LLD++ LE EI TY L+ +D
Sbjct: 353 HQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDD 391
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 300 bits (768), Expect = 2e-81
Identities = 173/411 (42%), Positives = 249/411 (60%), Gaps = 18/411 (4%)
Query: 8 AGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCL 67
+G+ GS + G GGS S Y S S S + F S G G +S S
Sbjct: 51 SGYGGGSSRVCGRGGGGSFGYS--YGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSS 108
Query: 68 PALCL-----PAGGFATSYSGGGGWFGE----------GILTGNEKETMQSLNDRLAGYL 112
GGF Y G G FG GILT NEK TMQ LN RLA YL
Sbjct: 109 GGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYL 168
Query: 113 EKVRQLEQENASLESRIREWCEQQVPYMCP-DYQSYFRTIEELQKKTLCSKAENARLVVE 171
+KV+ LE+ N LE++I++W +++ P +Y Y+ TI++L+ + + N + +++
Sbjct: 169 DKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLD 228
Query: 172 IDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCL 231
IDN ++ DDFR K+E E +LRQ V++DINGLR++LD+LT+ KSDLE Q E+L+EEL+ L
Sbjct: 229 IDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMAL 288
Query: 232 KKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQ 291
KKNH+EE++ L Q +NVE++ AP DL + L +MR +YE L+ NR+D E+ +TQ
Sbjct: 289 KKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQ 348
Query: 292 SEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQ 351
++ +V SS +++QS E+ +LR V LEIELQ+Q S + ALE +L +T+ RY Q
Sbjct: 349 ITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQ 408
Query: 352 LAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLE 402
L +Q I+N+EAQ+ ++R ++E QNQEY +LL ++ RLE EI TY LLE
Sbjct: 409 LQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLE 459
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 299 bits (765), Expect = 4e-81
Identities = 159/337 (47%), Positives = 235/337 (69%), Gaps = 6/337 (1%)
Query: 74 AGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWC 133
+GG AT +GG G GI NEKETMQSLNDRLA YL++VR LE EN LES+IRE
Sbjct: 60 SGGLATGIAGGLAGMG-GIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHL 116
Query: 134 EQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLR 193
E++ P + D+ YF+ IE+L+ + + +NAR+V++IDNA+LAADDFR KYETE+++R
Sbjct: 117 EKKGPQV-RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMR 175
Query: 194 QLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDR-LNV 252
Q VE+DI+GLR+++DD + + LE ++E+LKEELL +KKNHEEEV L+ Q+ L V
Sbjct: 176 QSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTV 235
Query: 253 EVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAE 312
EVDA DL +++ ++R QY+ L NR + + + Q EE V + S ++ + +
Sbjct: 236 EVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETT 295
Query: 313 IIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRAD 372
+ ELRRTV +LEI+L + +++ +LE++L E EARY+ Q+ Q+ ++ ++E++LA+ RA+
Sbjct: 296 LTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAE 355
Query: 373 LERQNQEYQVLLDVRARLECEINTYRGLLE-SEDSKL 408
+RQ QEY+ LL+++ +LE EI TYR LLE ED L
Sbjct: 356 GQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNL 392
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 299 bits (765), Expect = 4e-81
Identities = 159/337 (47%), Positives = 235/337 (69%), Gaps = 6/337 (1%)
Query: 74 AGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWC 133
+GG AT +GG G GI NEKETMQSLNDRLA YL++VR LE EN LES+IRE
Sbjct: 60 SGGLATGIAGGLAGMG-GIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHL 116
Query: 134 EQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLR 193
E++ P + D+ YF+ IE+L+ + + +NAR+V++IDNA+LAADDFR KYETE+++R
Sbjct: 117 EKKGPQV-RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMR 175
Query: 194 QLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDR-LNV 252
Q VE+DI+GLR+++DD + + LE ++E+LKEELL +KKNHEEEV L+ Q+ L V
Sbjct: 176 QSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTV 235
Query: 253 EVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAE 312
EVDA DL +++ ++R QY+ L NR + + + Q EE V + S ++ + +
Sbjct: 236 EVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETT 295
Query: 313 IIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRAD 372
+ ELRRTV +LEI+L + +++ +LE++L E EARY+ Q+ Q+ ++ ++E++LA+ RA+
Sbjct: 296 LTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAE 355
Query: 373 LERQNQEYQVLLDVRARLECEINTYRGLLE-SEDSKL 408
+RQ QEY+ LL+++ +LE EI TYR LLE ED L
Sbjct: 356 GQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNL 392
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 289 bits (739), Expect = 4e-78
Identities = 165/369 (44%), Positives = 232/369 (62%), Gaps = 16/369 (4%)
Query: 48 SFSACSVGLGRSSYRATSCLPALCLPAGGFATSYS--------GGGGWFGEG----ILTG 95
SF G GR R+ P + AGG S S GG W G G +L G
Sbjct: 14 SFHGAGGGWGRP--RSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSW-GSGRSSPLLGG 70
Query: 96 NEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQ 155
N K TMQ+LNDRLA YLEKVR LE+ N LESRI +W +Q+ P DY Y I LQ
Sbjct: 71 NGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQ 130
Query: 156 KKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKS 215
++ + K NA++++ IDNA++A DDF KYE E S ++ +E ++ GLRR LD+LT+ +
Sbjct: 131 EQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTT 190
Query: 216 DLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYET 275
DLE +VE +++EL+ +KK+HE+E+ +NV+VD P DL +VLE+MR +YE
Sbjct: 191 DLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYEL 250
Query: 276 LVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRD 335
+++ RD + W QS ++Q+ S + +QS Q +I EL+RT ALEI+LQ Q+S +
Sbjct: 251 IIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQALEIDLQTQYSTKS 309
Query: 336 ALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEIN 395
ALE+ L+ET++RYS +L MQ +I++ E +L ++R +LERQN EYQVLL ++ LE EI
Sbjct: 310 ALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEIT 369
Query: 396 TYRGLLESE 404
TYR LLE E
Sbjct: 370 TYRRLLEGE 378
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 286 bits (733), Expect = 2e-77
Identities = 171/397 (43%), Positives = 236/397 (59%), Gaps = 16/397 (4%)
Query: 22 SGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALCLPAGGFATSY 81
SGGS R+ + S LS F A +V +G + + SC G F S
Sbjct: 6 SGGSRRICSRTGSGR-----LSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSG 60
Query: 82 SGGG-----GWFGE--GILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCE 134
G G G+ G +L+GNEK TMQ+LNDRLA YL+ V LE+ NA LE +I+ E
Sbjct: 61 GGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYE 120
Query: 135 QQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEV 190
+ P DY YF IE+L+++ + NA +V++ DNA+L ADDFR KYE E+
Sbjct: 121 KCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENEL 180
Query: 191 SLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRL 250
+L VE+D +GLRR+LD+LTLC +DLE Q E+L EEL LKK+HEEE+ L+ G +
Sbjct: 181 ALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNV 240
Query: 251 NVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQ 310
NVE++A P VDL +L MR +YE L E NR+DAE W + +S L QQ+ + +
Sbjct: 241 NVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAAR 300
Query: 311 AEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIR 370
E+ EL+R + LEIELQ+ +++ + E +LAETE Y +QL Q+Q I +E QL +IR
Sbjct: 301 NELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIR 360
Query: 371 ADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSK 407
+ E Q EY+ LLDV+ LE EI+ Y LL+ E+ K
Sbjct: 361 TETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,441,506
Number of Sequences: 37866
Number of extensions: 822815
Number of successful extensions: 7355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 520
Number of HSP's that attempted gapping in prelim test: 5128
Number of HSP's gapped (non-prelim): 2007
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.