Guide to the Human Genome
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Name: SIGLEC8 Sequence: fasta or formatted (499aa) NCBI GI: 94538343
Description:

sialic acid binding Ig-like lectin 8

Referenced in:

Lectin Families
Neutrophils, Eosinophils, and Basophils

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.8         34           2
 C cysteine            2.4         12           1
 D aspartate           4.4         22           1
 E glutamate           4.6         23           2
 F phenylalanine       2.4         12           2
 G glycine             8.8         44           2
 H histidine           2.2         11           1
 I isoleucine          2.8         14           2
 K lysine              4.0         20           2
 L leucine            10.4         52           7
 M methionine          1.2          6           1
 N asparagine          3.0         15           2
 P proline             6.8         34           3
 Q glutamine           5.2         26           1
 R arginine            5.8         29           1
 S serine             10.6         53           2
 T threonine           8.0         40           3
 V valine              6.2         31           1
 W tryptophan          2.0         10           1
 Y tyrosine            2.2         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sialic acid binding Ig-like lectin 8 
SIGLEC7               0.626   sialic acid binding Ig-like lectin 7 isoform 1 
SIGLEC9               0.611   sialic acid binding Ig-like lectin 9 
SIGLEC12              0.611   sialic acid binding immunoglobulin-like lectin-like ...
SIGLEC12              0.606   sialic acid binding immunoglobulin-like lectin-like ...
SIGLEC6               0.385   sialic acid binding Ig-like lectin 6 isoform 1 prec...
SIGLEC6               0.360   sialic acid binding Ig-like lectin 6 isoform 2 prec...
SIGLEC14              0.332   sialic acid binding Ig-like lectin 14 
SIGLEC6               0.317   sialic acid binding Ig-like lectin 6 isoform 3 prec...
SIGLEC5               0.310   sialic acid binding Ig-like lectin 5 
SIGLEC7               0.304   sialic acid binding Ig-like lectin 7 isoform 2 [Hom...
CD33                  0.284   CD33 antigen isoform 1 precursor 
SIGLEC10              0.265   sialic acid binding Ig-like lectin 10 
SIGLEC11              0.247   sialic acid binding Ig-like lectin 11 isoform 2 [Ho...
SIGLEC11              0.247   sialic acid binding Ig-like lectin 11 isoform 1 [Ho...
CD33                  0.125   CD33 antigen isoform 2 precursor 
MAG                   0.103   myelin associated glycoprotein isoform a precursor [...
MAG                   0.103   myelin associated glycoprotein isoform b precursor [...
SIGLEC1               0.071   sialoadhesin precursor 
CD22                  0.056   CD22 molecule 
CADM4                 0.049   cell adhesion molecule 4 
PXDN                  0.039   peroxidasin 
CADM1                 0.034   immunoglobulin superfamily, member 4D isoform 2 [Ho...
HSPG2                 0.032   heparan sulfate proteoglycan 2 
PVRL2                 0.031   poliovirus receptor related 2 isoform alpha precursor...
PXDNL                 0.031   peroxidasin homolog-like 
TMIGD1                0.030   transmembrane and immunoglobulin domain containing [...
LOC100289200          0.029   PREDICTED: hypothetical protein XP_002342997 
LOC100292387          0.028   PREDICTED: similar to hemicentin 2 
HMCN2                 0.028   PREDICTED: hemicentin 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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