Guide to the Human Genome
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Search of human proteins with 89213247

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89213247 intermediate filament family orphan isoform 3 [Homo
sapiens]
         (200 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89213250 intermediate filament family orphan isoform 4 [Homo ...   402   e-112
gi|89213247 intermediate filament family orphan isoform 3 [Homo ...   402   e-112
gi|18490978 intermediate filament family orphan isoform 2 [Homo ...   395   e-111
gi|210147457 intermediate filament family orphan 2 [Homo sapiens]     210   6e-55
gi|14249342 internexin neuronal intermediate filament protein, a...    57   1e-08
gi|62414289 vimentin [Homo sapiens]                                    57   1e-08
gi|169168829 PREDICTED: similar to hCG1643231 [Homo sapiens]           54   7e-08
gi|169169468 PREDICTED: similar to hCG1643231 [Homo sapiens]           54   7e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    54   9e-08
gi|55749932 desmin [Homo sapiens]                                      54   1e-07
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     52   4e-07
gi|4504919 keratin 8 [Homo sapiens]                                    50   1e-06
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap...    50   1e-06
gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]    50   1e-06
gi|89357932 keratin 5b [Homo sapiens]                                  50   1e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     50   2e-06
gi|148612803 keratin 6 irs4 [Homo sapiens]                             49   2e-06
gi|15618995 keratin 71 [Homo sapiens]                                  49   3e-06
gi|27436951 lamin B2 [Homo sapiens]                                    49   3e-06
gi|21264345 peripherin [Homo sapiens]                                  49   4e-06
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                       48   6e-06
gi|125628636 keratin 80 isoform a [Homo sapiens]                       47   8e-06
gi|28173564 keratin 73 [Homo sapiens]                                  47   8e-06
gi|125628632 keratin 80 isoform b [Homo sapiens]                       47   8e-06
gi|153791158 keratin 75 [Homo sapiens]                                 45   3e-05
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                        45   4e-05
gi|67782365 keratin 7 [Homo sapiens]                                   45   4e-05
gi|32567786 keratin 6L [Homo sapiens]                                  45   4e-05
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                       45   4e-05
gi|148277620 type I hair keratin KA35 [Homo sapiens]                   45   5e-05

>gi|89213250 intermediate filament family orphan isoform 4 [Homo
           sapiens]
          Length = 563

 Score =  402 bits (1033), Expect = e-112
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD 60
           MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD
Sbjct: 364 MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD 423

Query: 61  SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ 120
           SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ
Sbjct: 424 SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ 483

Query: 121 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP 180
           IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP
Sbjct: 484 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP 543

Query: 181 PPPSEAEDSDRDVSSDSSMR 200
           PPPSEAEDSDRDVSSDSSMR
Sbjct: 544 PPPSEAEDSDRDVSSDSSMR 563


>gi|89213247 intermediate filament family orphan isoform 3 [Homo
           sapiens]
          Length = 200

 Score =  402 bits (1033), Expect = e-112
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD 60
           MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD
Sbjct: 1   MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD 60

Query: 61  SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ 120
           SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ
Sbjct: 61  SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ 120

Query: 121 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP 180
           IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP
Sbjct: 121 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP 180

Query: 181 PPPSEAEDSDRDVSSDSSMR 200
           PPPSEAEDSDRDVSSDSSMR
Sbjct: 181 PPPSEAEDSDRDVSSDSSMR 200


>gi|18490978 intermediate filament family orphan isoform 2 [Homo
           sapiens]
          Length = 559

 Score =  395 bits (1016), Expect = e-111
 Identities = 199/200 (99%), Positives = 199/200 (99%), Gaps = 1/200 (0%)

Query: 1   MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD 60
           MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD
Sbjct: 361 MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD 420

Query: 61  SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ 120
           SLTWEETEETLLLWEDFSGYAMAAAEAQGEQ EDSLEKVIKDTESLFKTREKEYQETIDQ
Sbjct: 421 SLTWEETEETLLLWEDFSGYAMAAAEAQGEQ-EDSLEKVIKDTESLFKTREKEYQETIDQ 479

Query: 121 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP 180
           IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP
Sbjct: 480 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP 539

Query: 181 PPPSEAEDSDRDVSSDSSMR 200
           PPPSEAEDSDRDVSSDSSMR
Sbjct: 540 PPPSEAEDSDRDVSSDSSMR 559


>gi|210147457 intermediate filament family orphan 2 [Homo sapiens]
          Length = 517

 Score =  210 bits (535), Expect = 6e-55
 Identities = 112/190 (58%), Positives = 141/190 (74%), Gaps = 6/190 (3%)

Query: 4   RKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLRE-YDFEDDCDSL 62
           +K+ERK A ++D S  + E  R  D   +E  +++I +EM+RM NQLRE +DF+DDCDSL
Sbjct: 325 KKKERKVASDDDISEQDGEVNRFSD---DEVGSMNITDEMKRMFNQLRETFDFDDDCDSL 381

Query: 63  TWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQIE 122
           TWEE E+TLLLWEDF+       + QGEQ+E+ L  +I +TES FKTR+KEYQETI QIE
Sbjct: 382 TWEENEDTLLLWEDFTN-CNPTIDLQGEQEEN-LGNLIHETESFFKTRDKEYQETIGQIE 439

Query: 123 LELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPPPP 182
           LELATAK+DMNRHLHEYMEMCSMKRGLDVQMETCRRLI  S DR SP+ ++V  SD    
Sbjct: 440 LELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGST 499

Query: 183 PSEAEDSDRD 192
               ++ +R+
Sbjct: 500 DEIQDEFERE 509


>gi|14249342 internexin neuronal intermediate filament protein,
           alpha [Homo sapiens]
          Length = 499

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 29/91 (31%), Positives = 51/91 (56%)

Query: 94  DSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQM 153
           +SLE+ I + E         YQ++I Q+E +L   K++M RHL EY ++ ++K  LD+++
Sbjct: 334 ESLERQILELEERHSAEVAGYQDSIGQLENDLRNTKSEMARHLREYQDLLNVKMALDIEI 393

Query: 154 ETCRRLITQSGDRKSPAFTAVPLSDPPPPPS 184
              R+L+     R S +  ++   +P P PS
Sbjct: 394 AAYRKLLEGEETRFSTSGLSISGLNPLPNPS 424


>gi|62414289 vimentin [Homo sapiens]
          Length = 466

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 28/88 (31%), Positives = 52/88 (59%), Gaps = 3/88 (3%)

Query: 94  DSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQM 153
           +SLE+ +++ E  F      YQ+TI +++ E+   K +M RHL EY ++ ++K  LD+++
Sbjct: 338 ESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEI 397

Query: 154 ETCRRLITQSGDRKS---PAFTAVPLSD 178
            T R+L+     R S   P F+++ L +
Sbjct: 398 ATYRKLLEGEESRISLPLPNFSSLNLRE 425


>gi|169168829 PREDICTED: similar to hCG1643231 [Homo sapiens]
          Length = 313

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 6/138 (4%)

Query: 26  QPDGDEEESTALSINEEMQRMLNQLREYD--FEDDCDSLTWEETEETLLLWEDFSGYAMA 83
           QPD   +E   L +  E+  M   + ++   ++D+ +  T E   E +L+ +D     + 
Sbjct: 91  QPDTLVQEK--LKLKAELGNMQGLVEDFKNKYKDEINKCT-EMENEFILIRKDMDDAYVN 147

Query: 84  AAEAQG-EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEM 142
            AE +G + Q  SLE  I D +   +   K+    + ++E  L  A  DM   LHEY ++
Sbjct: 148 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 207

Query: 143 CSMKRGLDVQMETCRRLI 160
            +MK  LD+++ T R+L+
Sbjct: 208 KNMKLALDIEIATYRKLL 225


>gi|169169468 PREDICTED: similar to hCG1643231 [Homo sapiens]
          Length = 315

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 6/138 (4%)

Query: 26  QPDGDEEESTALSINEEMQRMLNQLREYD--FEDDCDSLTWEETEETLLLWEDFSGYAMA 83
           QPD   +E   L +  E+  M   + ++   ++D+ +  T E   E +L+ +D     + 
Sbjct: 93  QPDTLVQEK--LKLEAELGNMQGLVEDFKNKYKDEINKCT-EMENEFILIRKDMDDAYVN 149

Query: 84  AAEAQG-EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEM 142
            AE +G + Q  SLE  I D +   +   K+    + ++E  L  A  DM   LHEY ++
Sbjct: 150 KAETEGLKSQRASLEATIADVKQRGELAIKDANTKLSKLEAALQQAMQDMAWQLHEYQKL 209

Query: 143 CSMKRGLDVQMETCRRLI 160
            +MK  LD+++ T R+L+
Sbjct: 210 KNMKLALDIEIATYRKLL 227


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 53.9 bits (128), Expect = 9e-08
 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 8/91 (8%)

Query: 93  EDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQ 152
           ++SLE+ + D E         YQ+TI Q+E EL   K +M RHL EY ++ ++K  LD++
Sbjct: 338 KESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIE 397

Query: 153 METCRRLI--------TQSGDRKSPAFTAVP 175
           +   R+L+        T +G    P +T  P
Sbjct: 398 IAAYRKLLEGEETRFSTFAGSITGPLYTHRP 428


>gi|55749932 desmin [Homo sapiens]
          Length = 470

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 24/67 (35%), Positives = 43/67 (64%)

Query: 94  DSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQM 153
           DSL + +++ E  F +    YQ+ I ++E E+   K++M RHL EY ++ ++K  LDV++
Sbjct: 343 DSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEI 402

Query: 154 ETCRRLI 160
            T R+L+
Sbjct: 403 ATYRKLL 409


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 26/81 (32%), Positives = 50/81 (61%), Gaps = 2/81 (2%)

Query: 94  DSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQM 153
           ++LEK +++ E          Q+TI+++E EL T K++M R+L EY ++ ++K  LD+++
Sbjct: 327 EALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEI 386

Query: 154 ETCRRLITQSGDRKSPAFTAV 174
              R+L+   G+    +FT+V
Sbjct: 387 AAYRKLL--EGEETRLSFTSV 405


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 1/77 (1%)

Query: 85  AEAQG-EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMC 143
           AE +G + Q  SLE  I D E   +   K+    + ++E  L  AK DM R L EY E+ 
Sbjct: 319 AEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELM 378

Query: 144 SMKRGLDVQMETCRRLI 160
           ++K  LD+++ T R+L+
Sbjct: 379 NVKLALDIEIATYRKLL 395


>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 23/73 (31%), Positives = 44/73 (60%)

Query: 94  DSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQM 153
           +SLE+ +++ E         YQE + ++E E  + K++M RHL EY ++ ++K  LD+++
Sbjct: 304 ESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEI 363

Query: 154 ETCRRLITQSGDR 166
            T R+L+    +R
Sbjct: 364 ATYRKLLEGEENR 376


>gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]
          Length = 432

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 23/73 (31%), Positives = 44/73 (60%)

Query: 94  DSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQM 153
           +SLE+ +++ E         YQE + ++E E  + K++M RHL EY ++ ++K  LD+++
Sbjct: 304 ESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEI 363

Query: 154 ETCRRLITQSGDR 166
            T R+L+    +R
Sbjct: 364 ATYRKLLEGEENR 376


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 30/84 (35%), Positives = 45/84 (53%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           ++Q  SL+  I D E   +   K+ Q  +D++E  L  AK ++ R L EY E+ S K  L
Sbjct: 347 KKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSL 406

Query: 150 DVQMETCRRLITQSGDRKSPAFTA 173
           DV++ T RRL+     R S   T+
Sbjct: 407 DVEIATYRRLLEGEECRMSGECTS 430


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 2/91 (2%)

Query: 93  EDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQ 152
           +DSLE+   + E   +     YQE I Q++ EL   K +M   L EY ++ ++K  LD++
Sbjct: 339 KDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIE 398

Query: 153 METCRRLITQSGDRKSPAFTAVPLSDPPPPP 183
           +   R+L+   G+     F  +P S P   P
Sbjct: 399 IAAYRKLL--EGEECRIGFGPIPFSLPEGLP 427


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 26/71 (36%), Positives = 41/71 (57%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           ++Q  SLE  I D E       K+ Q  +D++E  L  AK ++ R L EY E+ S+K  L
Sbjct: 376 KKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLAL 435

Query: 150 DVQMETCRRLI 160
           D+++ T R+L+
Sbjct: 436 DMEIATYRKLL 446


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 27/82 (32%), Positives = 44/82 (53%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           ++Q  +LE  I D E       K+ +  +D++E  L  AK ++ R L EY E+ S+K  L
Sbjct: 366 KKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLAL 425

Query: 150 DVQMETCRRLITQSGDRKSPAF 171
           D+++ T R+L+     R S  F
Sbjct: 426 DMEIATYRKLLESEECRMSGEF 447


>gi|27436951 lamin B2 [Homo sapiens]
          Length = 600

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 24/206 (11%)

Query: 4   RKRERKAAVEEDTSLSES---------EGPRQPDGDEEESTALSINEEMQRMLNQLR-EY 53
           R+R  +  VE D+S  +          E  R    ++     L + +  Q  L+  +   
Sbjct: 214 RRRHERRLVEVDSSRQQEYDFKMAQALEELRSQHDEQVRLYKLELEQTYQAKLDSAKLSS 273

Query: 54  DFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKE 113
           D  D   S   EE +E  +  E  S Y ++  + Q    ED     I++ E        +
Sbjct: 274 DQNDKAASAAREELKEARMRLESLS-YQLSGLQKQASAAEDR----IRELEEAMAGERDK 328

Query: 114 YQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTA 173
           +++ +D  E E+   ++ M + L EY E+  +K  LD+++   R+L+    +R       
Sbjct: 329 FRKMLDAKEQEMTEMRDVMQQQLAEYQELLDVKLALDMEINAYRKLLEGEEER------- 381

Query: 174 VPLSDPPPPPSEAEDSDRDVSSDSSM 199
             L   P P S    S    SS  S+
Sbjct: 382 --LKLSPSPSSRVTVSRATSSSSGSL 405


>gi|21264345 peripherin [Homo sapiens]
          Length = 470

 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 9/96 (9%)

Query: 94  DSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQM 153
           ++L + +++ E  F      YQ    ++E EL   K +M RHL EY E+ ++K  LD+++
Sbjct: 334 EALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEI 393

Query: 154 ETCRRLITQSGDRKSPAF---------TAVPLSDPP 180
            T R+L+     R S            T VP  +PP
Sbjct: 394 ATYRKLLEGEESRISVPVHSFASLNIKTTVPEVEPP 429


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score = 47.8 bits (112), Expect = 6e-06
 Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 4/111 (3%)

Query: 58  DCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQET 117
           D DS+  E   +    +E+ +  + A AE   + +   LE  I D E       K+ +  
Sbjct: 291 DLDSIIAEVRAQ----YEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDARAK 346

Query: 118 IDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKS 168
           +D++E  L  AK ++ R L EY E+ S+K  LD+++ T R+L+     R S
Sbjct: 347 LDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMS 397


>gi|125628636 keratin 80 isoform a [Homo sapiens]
          Length = 452

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 1/80 (1%)

Query: 96  LEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMET 155
           LE+ IK  E   +   ++ +  + Q+E  L  AK DM R L +Y E+ ++K  LD+++ T
Sbjct: 323 LEENIKTAEEQGELAFQDAKTKLAQLEAALQQAKQDMARQLRKYQELMNVKLALDIEIAT 382

Query: 156 CRRLIT-QSGDRKSPAFTAV 174
            R+L+  + G   SP+ T V
Sbjct: 383 YRKLVEGEEGRMDSPSATVV 402


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 27/83 (32%), Positives = 45/83 (54%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           ++Q  +LE  I D E       K+ +  +D++E  L  AK ++ R L EY E+ S+K  L
Sbjct: 368 KKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSL 427

Query: 150 DVQMETCRRLITQSGDRKSPAFT 172
           D+++ T R+L+     R S  +T
Sbjct: 428 DIEIATYRKLLEGEECRMSGEYT 450


>gi|125628632 keratin 80 isoform b [Homo sapiens]
          Length = 422

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 1/80 (1%)

Query: 96  LEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMET 155
           LE+ IK  E   +   ++ +  + Q+E  L  AK DM R L +Y E+ ++K  LD+++ T
Sbjct: 323 LEENIKTAEEQGELAFQDAKTKLAQLEAALQQAKQDMARQLRKYQELMNVKLALDIEIAT 382

Query: 156 CRRLIT-QSGDRKSPAFTAV 174
            R+L+  + G   SP+ T V
Sbjct: 383 YRKLVEGEEGRMDSPSATVV 402


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 5/93 (5%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           ++Q  SL+  I D E   +   K+ +  +  +E  L  AK DM R L EY E+ ++K  L
Sbjct: 385 KKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLAL 444

Query: 150 DVQMETCRRLI-----TQSGDRKSPAFTAVPLS 177
           DV++ T R+L+       SG+  SP   +V  S
Sbjct: 445 DVEIATYRKLLEGEECRLSGEGVSPVNISVVTS 477


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 26/79 (32%), Positives = 42/79 (53%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           ++Q   LE  I D E       K+ +  +D++E  L  AK ++ R L EY E+ S+K  L
Sbjct: 361 KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 420

Query: 150 DVQMETCRRLITQSGDRKS 168
           D+++ T R+L+     R S
Sbjct: 421 DMEIATYRKLLESEECRMS 439


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 23/71 (32%), Positives = 38/71 (53%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           + Q   LE  I + E   +   K+ +   +++E  L   K DM R L EY E+ S+K  L
Sbjct: 326 KNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLAL 385

Query: 150 DVQMETCRRLI 160
           D+++ T R+L+
Sbjct: 386 DIEIATYRKLL 396


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 23/79 (29%), Positives = 43/79 (54%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           ++Q   L+  I + E   +   K+ Q+ +  +++ L  AK D+ R L +Y E+ ++K  L
Sbjct: 380 KKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLAL 439

Query: 150 DVQMETCRRLITQSGDRKS 168
           DV++ T R+L+     R S
Sbjct: 440 DVEIATYRKLLESEESRMS 458


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 26/79 (32%), Positives = 42/79 (53%)

Query: 90  EQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGL 149
           ++Q   LE  I D E       K+ +  +D++E  L  AK ++ R L EY E+ S+K  L
Sbjct: 361 KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 420

Query: 150 DVQMETCRRLITQSGDRKS 168
           D+++ T R+L+     R S
Sbjct: 421 DMEIATYRKLLESEECRMS 439


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 1/91 (1%)

Query: 91  QQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLD 150
           +  DS E ++ +TE+ +     + Q  ID +E +LA  +  + R   EY  +  +K  L+
Sbjct: 331 RMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLE 390

Query: 151 VQMETCRRLITQSGDRKSPAFTAVPLSDPPP 181
            ++ T R L+ +S D K P +      +P P
Sbjct: 391 CEITTYRSLL-ESSDGKRPCYPRATKCEPSP 420


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.125    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,522,510
Number of Sequences: 37866
Number of extensions: 387607
Number of successful extensions: 3612
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 130
Number of HSP's successfully gapped in prelim test: 153
Number of HSP's that attempted gapping in prelim test: 3274
Number of HSP's gapped (non-prelim): 461
length of query: 200
length of database: 18,247,518
effective HSP length: 97
effective length of query: 103
effective length of database: 14,574,516
effective search space: 1501175148
effective search space used: 1501175148
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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