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Search of human proteins with 89063265
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 761 0.0
gi|17986001 major histocompatibility complex, class I, B precurs... 500 e-142
gi|24797067 major histocompatibility complex, class I, A precurs... 498 e-141
gi|52630342 major histocompatibility complex, class I, C precurs... 494 e-140
gi|62912479 major histocompatibility complex, class I, E precurs... 482 e-136
gi|4504415 major histocompatibility complex, class I, G precurso... 474 e-134
gi|149158702 major histocompatibility complex, class I, F isofor... 457 e-129
gi|149158698 major histocompatibility complex, class I, F isofor... 455 e-128
gi|149158700 major histocompatibility complex, class I, F isofor... 258 5e-69
gi|4504417 major histocompatibility complex, class I-related [Ho... 226 2e-59
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 210 2e-54
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 197 1e-50
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 193 2e-49
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 185 6e-47
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 166 2e-41
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 150 1e-36
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 150 1e-36
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 150 2e-36
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 140 2e-33
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 140 2e-33
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 119 3e-27
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 119 3e-27
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 110 3e-24
gi|110618224 CD1A antigen precursor [Homo sapiens] 95 1e-19
gi|4502649 CD1D antigen precursor [Homo sapiens] 76 5e-14
gi|110618227 CD1C antigen precursor [Homo sapiens] 75 1e-13
gi|4502645 CD1B antigen precursor [Homo sapiens] 73 5e-13
gi|4504399 major histocompatibility complex, class II, DM beta p... 71 2e-12
gi|239758095 PREDICTED: similar to major histocompatibility comp... 68 1e-11
gi|239740749 PREDICTED: similar to major histocompatibility comp... 68 1e-11
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 761 bits (1965), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MERDKSPLRPPGPITSDPGPDPAPRGGRARSHPSPPPGSHSLRYFYTAVSRPGLGEPRFI 60
MERDKSPLRPPGPITSDPGPDPAPRGGRARSHPSPPPGSHSLRYFYTAVSRPGLGEPRFI
Sbjct: 1 MERDKSPLRPPGPITSDPGPDPAPRGGRARSHPSPPPGSHSLRYFYTAVSRPGLGEPRFI 60
Query: 61 SVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYWDEQTRIVKDTAQSFRVGLNTLRG 120
SVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYWDEQTRIVKDTAQSFRVGLNTLRG
Sbjct: 61 SVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYWDEQTRIVKDTAQSFRVGLNTLRG 120
Query: 121 YYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQIT 180
YYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQIT
Sbjct: 121 YYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQIT 180
Query: 181 KRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRC 240
KRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRC
Sbjct: 181 KRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRC 240
Query: 241 WALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQH 300
WALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQH
Sbjct: 241 WALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQH 300
Query: 301 EGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGREGREGSEFSCHN 360
EGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGREGREGSEFSCHN
Sbjct: 301 EGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGREGREGSEFSCHN 360
Query: 361 GVSVRA 366
GVSVRA
Sbjct: 361 GVSVRA 366
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 500 bits (1287), Expect = e-142
Identities = 244/325 (75%), Positives = 272/325 (83%), Gaps = 4/325 (1%)
Query: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
GSHS+RYFYT+VSRPG GEPRFISVGYVDDTQFVRFDSD+A+PREEPRAPW+EQEGPEYW
Sbjct: 25 GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYW 84
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
D T+I K AQ+ R L LRGYYNQSEAGSHTLQ MYGCDVGPDGR LRG Q AYDG
Sbjct: 85 DRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDG 144
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
+DYIALNEDLRSWTAADTAAQIT+RK EAA AE++R YLEG CVE LRRYLE GKD L
Sbjct: 145 KDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLE 204
Query: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
RADPPK HVTHHPIS+ E TLRCWALGFYP EI+LTWQR+GEDQTQD ELVETRP+GD T
Sbjct: 205 RADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRT 264
Query: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEP-PQTSFLIMGIIVGLVLL---VVA 333
FQKWAA+VVPSGEEQRYTC VQHEGL +PLTLRWEP Q++ I+GI+ GL +L V+
Sbjct: 265 FQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIG 324
Query: 334 LVAGAVIWRKKRSGREGREGSEFSC 358
V AV+ R+K SG +G S+ +C
Sbjct: 325 AVVAAVMCRRKSSGGKGGSYSQAAC 349
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 498 bits (1282), Expect = e-141
Identities = 239/317 (75%), Positives = 270/317 (85%), Gaps = 4/317 (1%)
Query: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
GSHS+RYF+T+VSRPG GEPRFI+VGYVDDTQFVRFDSD+A+ R EPRAPW+EQEGPEYW
Sbjct: 25 GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYW 84
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
D++TR VK +Q+ RV L TLRGYYNQSEAGSHT+Q+MYGCDVG DGRFLRG+ QDAYDG
Sbjct: 85 DQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYGCDVGSDGRFLRGYRQDAYDG 144
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
+DYIALNEDLRSWTAAD AAQITKRK EAA AE+ R YL+G CVE LRRYLE GK+ L
Sbjct: 145 KDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAYLDGTCVEWLRRYLENGKETLQ 204
Query: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
R DPPK H+THHPIS+ E TLRCWALGFYP EI+LTWQR+GEDQTQD ELVETRP+GDGT
Sbjct: 205 RTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT 264
Query: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLL---VVA 333
FQKWAA+VVPSGEEQRYTC VQHEGL +PLTLRWE Q + I+GII GLVLL +
Sbjct: 265 FQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITG 324
Query: 334 LVAGAVIWRKKRSGREG 350
V AV+WR+K S R+G
Sbjct: 325 AVVAAVMWRRKSSDRKG 341
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 494 bits (1271), Expect = e-140
Identities = 241/327 (73%), Positives = 271/327 (82%), Gaps = 5/327 (1%)
Query: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYWD 98
SHS+RYF TAVSRPG GEPRFISVGYVDDTQFVRFDSD+A+PR EPRAPW+EQEGPEYWD
Sbjct: 26 SHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWD 85
Query: 99 EQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGR 158
+T+ K AQ+ RV L LRGYYNQSE GSHTLQ M GCD+GPDGR LRG+ Q AYDG+
Sbjct: 86 RETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGK 145
Query: 159 DYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALLR 218
DYIALNEDLRSWTAADTAAQIT+RK EAA AAE+ R YLEG CVE LRRYLE GK+ L R
Sbjct: 146 DYIALNEDLRSWTAADTAAQITQRKLEAARAAEQLRAYLEGTCVEWLRRYLENGKETLQR 205
Query: 219 ADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTF 278
A+PPK HVTHHP+S+ E TLRCWALGFYP EI+LTWQR+GEDQTQD ELVETRP+GDGTF
Sbjct: 206 AEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTF 265
Query: 279 QKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEP-PQTSFLIMGIIVGLVLLVVALVAG 337
QKWAA+VVPSG+EQRYTC +QHEGLQEPLTL WEP Q + IMGI+ GL +LVV V G
Sbjct: 266 QKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLG 325
Query: 338 AVI----WRKKRSGREGREGSEFSCHN 360
AV+ R+K SG +G S+ +C N
Sbjct: 326 AVVTAMMCRRKSSGGKGGSCSQAACSN 352
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 482 bits (1240), Expect = e-136
Identities = 231/317 (72%), Positives = 262/317 (82%), Gaps = 4/317 (1%)
Query: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
GSHSL+YF+T+VSRPG GEPRFISVGYVDDTQFVRFD+D+A+PR PRAPWMEQEG EYW
Sbjct: 22 GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYW 81
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
D +TR +DTAQ FRV L TLRGYYNQSEAGSHTLQ M+GC++GPDGRFLRG+ Q AYDG
Sbjct: 82 DRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDG 141
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
+DY+ LNEDLRSWTA DTAAQI+++K A AE QR YLE CVE L +YLE GK+ LL
Sbjct: 142 KDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLL 201
Query: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
+PPK HVTHHPIS+ E TLRCWALGFYP EI+LTWQ++GE TQD ELVETRP+GDGT
Sbjct: 202 HLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGT 261
Query: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPP-QTSFLIMGIIVGLVLL---VVA 333
FQKWAA+VVPSGEEQRYTC VQHEGL EP+TLRW+P Q + I+GII GLVLL V
Sbjct: 262 FQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSG 321
Query: 334 LVAGAVIWRKKRSGREG 350
V AVIWRKK SG +G
Sbjct: 322 AVVAAVIWRKKSSGGKG 338
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 474 bits (1219), Expect = e-134
Identities = 230/313 (73%), Positives = 257/313 (82%), Gaps = 4/313 (1%)
Query: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
GSHS+RYF AVSRPG GEPRFI++GYVDDTQFVRFDSDSA PR EPRAPW+EQEGPEYW
Sbjct: 25 GSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQEGPEYW 84
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
+E+TR K AQ+ R+ L TLRGYYNQSEA SHTLQ M GCD+G DGR LRG+ Q AYDG
Sbjct: 85 EEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCDLGSDGRLLRGYEQYAYDG 144
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
+DY+ALNEDLRSWTAADTAAQI+KRK EAA AE++R YLEG CVE L RYLE GK+ L
Sbjct: 145 KDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAYLEGTCVEWLHRYLENGKEMLQ 204
Query: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
RADPPK HVTHHP+ + E TLRCWALGFYP EI LTWQR+GEDQTQD+ELVETRP+GDGT
Sbjct: 205 RADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQRDGEDQTQDVELVETRPAGDGT 264
Query: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFL-IMGIIVGLVLL---VVA 333
FQKWAA+VVPSGEEQRYTC VQHEGL EPL LRW+ + IMGI+ GLV+L V
Sbjct: 265 FQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTG 324
Query: 334 LVAGAVIWRKKRS 346
AV+WRKK S
Sbjct: 325 AAVAAVLWRKKSS 337
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 457 bits (1177), Expect = e-129
Identities = 227/330 (68%), Positives = 258/330 (78%), Gaps = 4/330 (1%)
Query: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
GSHSLRYF TAVSRPG GEPR+I+V YVDDTQF+RFDSD+A PR EPR PW+EQEGP+YW
Sbjct: 22 GSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYW 81
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
+ T K AQ+ RV L L YNQSEAGSHTLQ M GCD+GPDGR LRG+ Q AYDG
Sbjct: 82 EWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDG 141
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
+DYI+LNEDLRSWTAADT AQIT+R EA AE R YLEG C+E LRRYLE GK+ L
Sbjct: 142 KDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQ 201
Query: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
RADPPKAHV HHPIS+ E TLRCWALGFYP EI+LTWQR+GE+QTQD ELVETRP+GDGT
Sbjct: 202 RADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGT 261
Query: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLL---VVA 333
FQKWAA+VVP GEEQRYTC VQHEGL +PL LRWE PQ + I+GI+ GLV+L V
Sbjct: 262 FQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTG 321
Query: 334 LVAGAVIWRKKRSGREGREGSEFSCHNGVS 363
V AV+WRKK S R S+ + ++ VS
Sbjct: 322 AVVAAVMWRKKSSDRNRGSYSQAAAYSVVS 351
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 455 bits (1171), Expect = e-128
Identities = 224/315 (71%), Positives = 251/315 (79%), Gaps = 4/315 (1%)
Query: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
GSHSLRYF TAVSRPG GEPR+I+V YVDDTQF+RFDSD+A PR EPR PW+EQEGP+YW
Sbjct: 22 GSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYW 81
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
+ T K AQ+ RV L L YNQSEAGSHTLQ M GCD+GPDGR LRG+ Q AYDG
Sbjct: 82 EWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDG 141
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
+DYI+LNEDLRSWTAADT AQIT+R EA AE R YLEG C+E LRRYLE GK+ L
Sbjct: 142 KDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQ 201
Query: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
RADPPKAHV HHPIS+ E TLRCWALGFYP EI+LTWQR+GE+QTQD ELVETRP+GDGT
Sbjct: 202 RADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGT 261
Query: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLL---VVA 333
FQKWAA+VVP GEEQRYTC VQHEGL +PL LRWE PQ + I+GI+ GLV+L V
Sbjct: 262 FQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTG 321
Query: 334 LVAGAVIWRKKRSGR 348
V AV+WRKK S R
Sbjct: 322 AVVAAVMWRKKSSDR 336
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 258 bits (660), Expect = 5e-69
Identities = 128/183 (69%), Positives = 144/183 (78%)
Query: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
GSHSLRYF TAVSRPG GEPR+I+V YVDDTQF+RFDSD+A PR EPR PW+EQEGP+YW
Sbjct: 22 GSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQEGPQYW 81
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
+ T K AQ+ RV L L YNQSEAGSHTLQ M GCD+GPDGR LRG+ Q AYDG
Sbjct: 82 EWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDG 141
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
+DYI+LNEDLRSWTAADT AQIT+R EA AE R YLEG C+E LRRYLE GK+ L
Sbjct: 142 KDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQ 201
Query: 218 RAD 220
RA+
Sbjct: 202 RAE 204
Score = 37.4 bits (85), Expect = 0.021
Identities = 22/51 (43%), Positives = 29/51 (56%), Gaps = 3/51 (5%)
Query: 301 EGLQEPLTLRWEPPQTSFLIMGIIVGLVLL---VVALVAGAVIWRKKRSGR 348
E +E L + PQ + I+GI+ GLV+L V V AV+WRKK S R
Sbjct: 194 ENGKETLQRAEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDR 244
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 226 bits (577), Expect = 2e-59
Identities = 126/315 (40%), Positives = 180/315 (57%), Gaps = 9/315 (2%)
Query: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWM-EQEGPEYW 97
+HSLRYF VS P G P FISVGYVD +DS ++EPRAPWM E P++W
Sbjct: 24 THSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTRQKEPRAPWMAENLAPDHW 81
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
+ T++++ Q F+V L L+ +YN S GSHT Q M GC++ DG GF+Q AYDG
Sbjct: 82 ERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELLEDGS-TTGFLQYAYDG 138
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREA-AGAAERQRNYLEGRCVEGLRRYLETGKDAL 216
+D++ N+D SW A D A K+ EA Q+N+LE C+ L+R+LE GKD L
Sbjct: 139 QDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTL 198
Query: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDG 276
R +PP V L C A GFYP EI +TW + GE+ Q+++ + PSGDG
Sbjct: 199 QRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDG 258
Query: 277 TFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALV- 335
T+Q WA++ + Y+C V+H G+ L + E +T L+M + G ++LV+ L
Sbjct: 259 TYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVLAG 317
Query: 336 AGAVIWRKKRSGREG 350
G ++WR++ + G
Sbjct: 318 VGVLVWRRRPREQNG 332
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 210 bits (534), Expect = 2e-54
Identities = 122/319 (38%), Positives = 177/319 (55%), Gaps = 9/319 (2%)
Query: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97
SHSL Y + S LG F ++GYVDD FV +D +S R EPR PW+ + W
Sbjct: 27 SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
+ ++ +K F V T+ +N S+ SHTLQ++ GC++ D G+ + YDG
Sbjct: 85 LQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDG 142
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQ-RNYLEGRCVEGLRRYLETGKDAL 216
+D++ D W AA+ A TK + E RQ R YLE C L++ LE G+ L
Sbjct: 143 QDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVL 202
Query: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGD 275
+ PP VTHH ++ TLRC AL +YP+ I++ W ++ + ++ E + P+GD
Sbjct: 203 DQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 261
Query: 276 GTFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALV 335
GT+Q W L VP GEEQRYTC+V+H GL +PL + WEP + L++G+I G+ + VV L
Sbjct: 262 GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILF 321
Query: 336 AGAV-IWRKKRSGREGREG 353
G + I +KR G G G
Sbjct: 322 IGILFIILRKRQGSRGAMG 340
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 197 bits (501), Expect = 1e-50
Identities = 114/300 (38%), Positives = 168/300 (56%), Gaps = 9/300 (3%)
Query: 58 RFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYWDEQTRIVKDTAQSFRVGLN 116
R + +GYVDD FV +D +S R EPR PW+ + W + ++ +K F V
Sbjct: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
Query: 117 TLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTA 176
T+ +N S+ SHTLQ++ GC++ D G+ + YDG+D++ D W AA+
Sbjct: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
Query: 177 AQITKRKREAAGAAERQ-RNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISERE 235
A TK + E RQ R YLE C L++ LE G+ L + PP VTHH ++
Sbjct: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
Query: 236 VTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRY 294
TLRC AL +YP+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRY
Sbjct: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
Query: 295 TCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353
TC+V+H GL +PL + WEP + L++G+I G+ + VV L G + I +KR G G G
Sbjct: 258 TCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 317
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 193 bits (491), Expect = 2e-49
Identities = 116/319 (36%), Positives = 170/319 (53%), Gaps = 23/319 (7%)
Query: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97
SHSL Y + S LG F ++GYVDD FV +D +S R EPR PW+ + W
Sbjct: 27 SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
+ ++ +K F V T+ +N S+ SHTLQ++ GC++ D G+ + YDG
Sbjct: 85 LQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDG 142
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQ-RNYLEGRCVEGLRRYLETGKDAL 216
+D++ D W AA+ A TK + E RQ R YLE C L++ LE G+ L
Sbjct: 143 QDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVL 202
Query: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGD 275
++ TLRC AL +YP+ I++ W ++ + ++ E + P+GD
Sbjct: 203 ---------------DQQVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 247
Query: 276 GTFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALV 335
GT+Q W L VP GEEQRYTC+V+H GL +PL + WEP + L++G+I G+ + VV L
Sbjct: 248 GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILF 307
Query: 336 AGAV-IWRKKRSGREGREG 353
G + I +KR G G G
Sbjct: 308 IGILFIILRKRQGSRGAMG 326
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 185 bits (469), Expect = 6e-47
Identities = 102/276 (36%), Positives = 150/276 (54%), Gaps = 6/276 (2%)
Query: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
G +SL Y YT +S+ P F ++G ++D QF R++S + +P W + EG E W
Sbjct: 26 GRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDR--KSQPMGLWRQVEGMEDW 83
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
+ +++ K F L + YYN S GSH LQ +GC++ + R F + YDG
Sbjct: 84 KQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI-ENNRSSGAFWKYYYDG 141
Query: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGA-AERQRNYLEGRCVEGLRRYLETGKDAL 216
+DYI N+++ +W D AAQITK+K EA +R + YLE C LR+YL+ K+ L
Sbjct: 142 KDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNIL 201
Query: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDG 276
R DPP VT H + L+C A FYP +I + W R GE Q ++ + +G+G
Sbjct: 202 DRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELR-GDVLHNGNG 260
Query: 277 TFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE 312
T+Q W + VP + Y+C VQH L +PL + WE
Sbjct: 261 TYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWE 296
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 166 bits (421), Expect = 2e-41
Identities = 91/228 (39%), Positives = 132/228 (57%), Gaps = 5/228 (2%)
Query: 129 SHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQITKRKREAAG 188
SHTLQ++ GC++ D G+ + YDG+D++ D W AA+ A TK + E
Sbjct: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 189 AAERQ-RNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRCWALGFYP 247
RQ R YLE C L++ LE G+ L + PP VTHH ++ TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
Query: 248 EEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGLQEP 306
+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRYTC+V+H GL +P
Sbjct: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
Query: 307 LTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353
L + WEP + L++G+I G+ + VV L G + I +KR G G G
Sbjct: 205 LIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 252
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 150 bits (380), Expect = 1e-36
Identities = 102/312 (32%), Positives = 159/312 (50%), Gaps = 18/312 (5%)
Query: 41 SLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWM-EQEGPEYWDE 99
SL Y TAVS P G P F G++ Q++ ++S EP W+ E + YW++
Sbjct: 29 SLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRGEAEPCGAWVWENQVSWYWEK 86
Query: 100 QTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRD 159
+T ++ + F L G G +TLQ + GC++GPD + + A +G +
Sbjct: 87 ETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCELGPDNTSVPT-AKFALNGEE 139
Query: 160 YIALNEDLRSWTAADT---AAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDAL 216
+ +N DL+ T A I++R ++ AA ++ +L C LR +LE G+ L
Sbjct: 140 F--MNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNL 197
Query: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDG 276
+PP + P S L C A FYP E+ L + R G + P+ DG
Sbjct: 198 EWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQG--DFGPNSDG 255
Query: 277 TFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLLVVALV 335
+F ++L V SG+E Y C VQH GL +PL + E P ++S L++GI++G++LL A V
Sbjct: 256 SFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAV 315
Query: 336 AGAVIWRKKRSG 347
GA++WR+ RSG
Sbjct: 316 GGALLWRRMRSG 327
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 150 bits (380), Expect = 1e-36
Identities = 102/312 (32%), Positives = 159/312 (50%), Gaps = 18/312 (5%)
Query: 41 SLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWM-EQEGPEYWDE 99
SL Y TAVS P G P F G++ Q++ ++S EP W+ E + YW++
Sbjct: 29 SLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRGEAEPCGAWVWENQVSWYWEK 86
Query: 100 QTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRD 159
+T ++ + F L G G +TLQ + GC++GPD + + A +G +
Sbjct: 87 ETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCELGPDNTSVPT-AKFALNGEE 139
Query: 160 YIALNEDLRSWTAADT---AAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDAL 216
+ +N DL+ T A I++R ++ AA ++ +L C LR +LE G+ L
Sbjct: 140 F--MNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNL 197
Query: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDG 276
+PP + P S L C A FYP E+ L + R G + P+ DG
Sbjct: 198 EWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQG--DFGPNSDG 255
Query: 277 TFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLLVVALV 335
+F ++L V SG+E Y C VQH GL +PL + E P ++S L++GI++G++LL A V
Sbjct: 256 SFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAV 315
Query: 336 AGAVIWRKKRSG 347
GA++WR+ RSG
Sbjct: 316 GGALLWRRMRSG 327
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 150 bits (378), Expect = 2e-36
Identities = 85/228 (37%), Positives = 125/228 (54%), Gaps = 19/228 (8%)
Query: 129 SHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQITKRKREAAG 188
SHTLQ++ GC++ D G+ + YDG+D++ D W AA+ A TK + E
Sbjct: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 189 AAERQ-RNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRCWALGFYP 247
RQ R YLE C L++ LE G+ L ++ TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVL---------------DQQVTTLRCRALNYYP 130
Query: 248 EEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGLQEP 306
+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRYTC+V+H GL +P
Sbjct: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
Query: 307 LTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353
L + WEP + L++G+I G+ + VV L G + I +KR G G G
Sbjct: 191 LIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 238
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 140 bits (353), Expect = 2e-33
Identities = 97/342 (28%), Positives = 165/342 (48%), Gaps = 28/342 (8%)
Query: 29 ARSHPSPPPGS----HSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEP 84
A + P PP + HSLRY +S+ G + F++ G++D F+R+D R +P
Sbjct: 11 AVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR--RAKP 68
Query: 85 RAPWMEQE-GPEYWDEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPD 143
+ W E G + WD +T + + Q R L ++ + G H+LQ + C++ D
Sbjct: 69 QGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIK----DQKGGLHSLQEIRVCEIHED 124
Query: 144 GRFLRGFMQDAYDGRDYIALNEDLRSWT------AADTAAQITKRKREAAGAAERQRNYL 197
RG YDG +++ N + + T A A +T +E A + +
Sbjct: 125 SS-TRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAM 183
Query: 198 EGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQRE 257
+ C++ L+RYL++G A+ R PP +VT +SE +T+ C A FYP I+LTW+++
Sbjct: 184 QADCLQKLQRYLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQD 242
Query: 258 GEDQTQD-MELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEG------LQEPLTLR 310
G + + + + P G+GT+Q W A + GEEQR+TC ++H G + L
Sbjct: 243 GVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALV 302
Query: 311 WEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGREGRE 352
+ +T F + + ++++ L +KK S EG E
Sbjct: 303 LQSQRTDFPYVSAAMPCFVIIIILCVPCC--KKKTSAAEGPE 342
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 140 bits (352), Expect = 2e-33
Identities = 99/342 (28%), Positives = 157/342 (45%), Gaps = 36/342 (10%)
Query: 33 PSPPPGS----HSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPW 88
P PPG+ HSLRY T +S G + F++ ++D F+R D R +P+ W
Sbjct: 15 PFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC--RAKPQGQW 72
Query: 89 MEQE-GPEYWDEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFL 147
E G + WD +TR + + R+ L + + G H+LQ + C++ D
Sbjct: 73 AEDVLGNKTWDRETRDLTGNGKDLRMTL----AHIKDQKEGLHSLQEIRVCEIHEDNS-T 127
Query: 148 RGFMQDAYDGRDYIALNEDLRSWT------AADTAAQITKRKREAAGAAERQRNYLEGRC 201
R YDG +++ N + + WT A A + +E A + + + C
Sbjct: 128 RSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC 187
Query: 202 VEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ 261
++ LRRYL++G L R PP +VT SE +T+ C A GFYP I+L+W+++G
Sbjct: 188 LQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSL 246
Query: 262 TQD-MELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGLQEP----------LTLR 310
+ D + + P G+GT+Q W A + GEEQR+TC ++H G L
Sbjct: 247 SHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSH 306
Query: 311 WEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGREGRE 352
W+ S + I +++ V +KK S EG E
Sbjct: 307 WQTFHVSAVAAAAIFVIIIFYVRCC------KKKTSAAEGPE 342
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 119 bits (299), Expect = 3e-27
Identities = 58/135 (42%), Positives = 84/135 (62%), Gaps = 3/135 (2%)
Query: 221 PPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQ 279
PP VTHH ++ TLRC AL +YP+ I++ W ++ + ++ E + P+GDGT+Q
Sbjct: 27 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 280 KWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV 339
W L VP GEEQRYTC+V+H GL +PL + WEP + L++G+I G+ + VV L G +
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
Query: 340 -IWRKKRSGREGREG 353
I +KR G G G
Sbjct: 146 FIILRKRQGSRGAMG 160
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 119 bits (299), Expect = 3e-27
Identities = 58/135 (42%), Positives = 84/135 (62%), Gaps = 3/135 (2%)
Query: 221 PPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQ 279
PP VTHH ++ TLRC AL +YP+ I++ W ++ + ++ E + P+GDGT+Q
Sbjct: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
Query: 280 KWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV 339
W L VP GEEQRYTC+V+H GL +PL + WEP + L++G+I G+ + VV L G +
Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 233
Query: 340 -IWRKKRSGREGREG 353
I +KR G G G
Sbjct: 234 FIILRKRQGSRGAMG 248
Score = 53.1 bits (126), Expect = 4e-07
Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97
SHSL Y + S LG F ++GYVDD FV +D +S R EPR PW+ + W
Sbjct: 27 SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSE 126
+ ++ +K F V T+ +N S+
Sbjct: 85 LQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 110 bits (274), Expect = 3e-24
Identities = 52/119 (43%), Positives = 76/119 (63%), Gaps = 2/119 (1%)
Query: 237 TLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYT 295
TLRC AL +YP+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRYT
Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
Query: 296 CRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353
C+V+H GL +PL + WEP + L++G+I G+ + VV L G + I +KR G G G
Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
Score = 53.1 bits (126), Expect = 4e-07
Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97
SHSL Y + S LG F ++GYVDD FV +D +S R EPR PW+ + W
Sbjct: 27 SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84
Query: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSE 126
+ ++ +K F V T+ +N S+
Sbjct: 85 LQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 94.7 bits (234), Expect = 1e-19
Identities = 82/293 (27%), Positives = 134/293 (45%), Gaps = 25/293 (8%)
Query: 63 GYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYWDEQTRIVK-DTAQSFRVGLNTLRG 120
G++ D Q +DS+S+ PW E W E + + T +SF +R
Sbjct: 47 GWLSDLQTHTWDSNSSTIVF--LCPWSRGNFSNEEWKELETLFRIRTIRSFE----GIRR 100
Query: 121 YYNQSEAG-SHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQI 179
Y ++ + +Q+ GC++ G+ F+Q AY G D+++ + SW A +
Sbjct: 101 YAHELQFEYPFEIQVTGGCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNM 157
Query: 180 TKRKREAAGAAERQR----NYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI-SER 234
K + + + N L C + L+ GK L R P+A ++H P
Sbjct: 158 AKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPG 217
Query: 235 EVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRY 294
+ L C GFYP+ + + W R GE + Q + + PS DGT+ A L V +GE
Sbjct: 218 HLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADL 276
Query: 295 TCRVQHEGLQ-EPLTLRWE-PPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKR 345
+CRV+H L+ + + L WE F+I+ +IV L+LL+ G +W +KR
Sbjct: 277 SCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLI-----GLALWFRKR 324
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 75.9 bits (185), Expect = 5e-14
Identities = 62/225 (27%), Positives = 100/225 (44%), Gaps = 11/225 (4%)
Query: 132 LQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQITKRKREAAGAAE 191
LQ+ GC+V P G F A+ G+D ++ SW A + +
Sbjct: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
Query: 192 RQRN----YLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI-SEREVTLRCWALGFY 246
R L G C + + LE+GK L + PKA ++ P + L C GFY
Sbjct: 171 WTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFY 230
Query: 247 PEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGLQ-E 305
P+ + + W R GE + Q + + P+ D T+ A L V +GE +CRV+H L+ +
Sbjct: 231 PKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQ 289
Query: 306 PLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGREG 350
+ L W TS ++ + V L L+ L+ G K+++ +G
Sbjct: 290 DIVLYWGGSYTSMGLIALAV-LACLLFLLIVGFTSRFKRQTSYQG 333
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 74.7 bits (182), Expect = 1e-13
Identities = 60/223 (26%), Positives = 106/223 (47%), Gaps = 21/223 (9%)
Query: 132 LQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQITKR-----KREA 186
+Q+ GC++ G+ GF Q A++G D ++ +W + + + +
Sbjct: 114 VQVKAGCELH-SGKSPEGFFQVAFNGLDLLSFQNT--TWVPSPGCGSLAQSVCHLLNHQY 170
Query: 187 AGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHP-ISEREVTLRCWALGF 245
G E N + C L L+ GK + R P+A ++ P + ++ L C A GF
Sbjct: 171 EGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGF 230
Query: 246 YPEEISLTWQREGEDQ--TQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGL 303
YP+ + +TW R ++Q T+ +++ P+ DGT+ L V S E +CRV+H L
Sbjct: 231 YPKPVWVTWMRNEQEQLGTKHGDIL---PNADGTWYLQVILEVASEEPAGLSCRVRHSSL 287
Query: 304 -QEPLTLRW-EPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKK 344
+ + L W +++ + +IV LV+L+V V+W KK
Sbjct: 288 GGQDIILYWGHHFSMNWIALVVIVPLVILIV-----LVLWFKK 325
>gi|4502645 CD1B antigen precursor [Homo sapiens]
Length = 333
Score = 72.8 bits (177), Expect = 5e-13
Identities = 76/296 (25%), Positives = 129/296 (43%), Gaps = 30/296 (10%)
Query: 63 GYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYWDEQTRIVKDTAQSFRVGLNTLRGYY 122
G++DD Q +DSDS PW + + D++ V + + FRV + G+
Sbjct: 48 GWLDDLQIHGWDSDSGTAIF--LKPWSKGN---FSDKE---VAELEEIFRV---YIFGFA 96
Query: 123 NQSEAGSHTLQLMY--------GCDVGPDGRFLRGFMQDAYDGRDYIALNED--LRSWTA 172
+ + + Q+ Y GC++ G + F++ A G D++++ + S
Sbjct: 97 REVQDFAGDFQMKYPFEIQGIAGCELHSGGAIV-SFLRGALGGLDFLSVKNASCVPSPEG 155
Query: 173 ADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI- 231
A + + G E R L C L L GK L R P+A ++ P
Sbjct: 156 GSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSP 215
Query: 232 SEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEE 291
+ L C GFYP+ + + W R GE + Q +L + P+ + T+ A L V GE
Sbjct: 216 GPGRLQLVCHVSGFYPKPVWVMWMR-GEQEQQGTQLGDILPNANWTWYLRATLDVADGEA 274
Query: 292 QRYTCRVQHEGLQ-EPLTLRW-EPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKR 345
+CRV+H L+ + + L W P +++ IIV +LL++ L +W +R
Sbjct: 275 AGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCL----ALWYMRR 326
>gi|4504399 major histocompatibility complex, class II, DM beta
precursor [Homo sapiens]
Length = 263
Score = 70.9 bits (172), Expect = 2e-12
Identities = 42/132 (31%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 218 RADPPKAHVTHH-PISERE-VTLRCWALGFYPEEISLTWQREGEDQTQDMELVET-RPSG 274
R PP V P + RE V L C+ GFYP E+++TW++ G+ +T +P+G
Sbjct: 111 RTRPPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNG 170
Query: 275 DGTFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVAL 334
D T+Q + L + YTC V+H G EP+ W P + + + V V L + L
Sbjct: 171 DWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLKVSVSAVTLGLGL 230
Query: 335 V---AGAVIWRK 343
+ G + WR+
Sbjct: 231 IIFSLGVISWRR 242
>gi|239758095 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 68.2 bits (165), Expect = 1e-11
Identities = 51/179 (28%), Positives = 76/179 (42%), Gaps = 15/179 (8%)
Query: 179 ITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTL 238
I +RKR A R LE LR L+ + + P + +H L
Sbjct: 99 ILERKRAAVDRVCRHNYQLE------LRTTLQRRVEPTVTISPSRTEALNH-----HNLL 147
Query: 239 RCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRV 298
C FYP +I + W R G+++T + +GD TFQ L + YTC V
Sbjct: 148 VCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHV 207
Query: 299 QHEGLQEPLTLRWEPPQTS--FLIMGIIVGLVLLVVALVAGAVIWRKKRSGRE--GREG 353
+H LQ P+T+ W S ++ I G VL ++ L G +I + + G E G+ G
Sbjct: 208 EHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQGKRG 266
>gi|239740749 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 68.2 bits (165), Expect = 1e-11
Identities = 51/179 (28%), Positives = 76/179 (42%), Gaps = 15/179 (8%)
Query: 179 ITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISEREVTL 238
I +RKR A R LE LR L+ + + P + +H L
Sbjct: 99 ILERKRAAVDRVCRHNYQLE------LRTTLQRRVEPTVTISPSRTEALNH-----HNLL 147
Query: 239 RCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRV 298
C FYP +I + W R G+++T + +GD TFQ L + YTC V
Sbjct: 148 VCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHV 207
Query: 299 QHEGLQEPLTLRWEPPQTS--FLIMGIIVGLVLLVVALVAGAVIWRKKRSGRE--GREG 353
+H LQ P+T+ W S ++ I G VL ++ L G +I + + G E G+ G
Sbjct: 208 EHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQGKRG 266
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,561,290
Number of Sequences: 37866
Number of extensions: 965452
Number of successful extensions: 6500
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 5854
Number of HSP's gapped (non-prelim): 694
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.