Guide to the Human Genome
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Search of human proteins with 7662322

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662322 thymus high mobility group box protein TOX [Homo
sapiens]
         (526 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662322 thymus high mobility group box protein TOX [Homo sapi...  1095   0.0  
gi|149408144 TOX high mobility group box family member 2 isoform...   397   e-110
gi|226054295 TOX high mobility group box family member 3 isoform...   380   e-105
gi|149408141 TOX high mobility group box family member 2 isoform...   369   e-102
gi|14249636 TOX high mobility group box family member 2 isoform ...   369   e-102
gi|226246533 TOX high mobility group box family member 3 isoform...   365   e-101
gi|149408146 TOX high mobility group box family member 2 isoform...   328   1e-89
gi|7662274 epidermal Langerhans cell protein LCP1 [Homo sapiens]      287   1e-77
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]           82   1e-15
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]           82   1e-15
gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]           82   1e-15
gi|4504425 high-mobility group box 1 [Homo sapiens]                    80   5e-15
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]             77   3e-14
gi|194688135 high-mobility group box 2 [Homo sapiens]                  76   9e-14
gi|194688133 high-mobility group box 2 [Homo sapiens]                  76   9e-14
gi|11321591 high-mobility group box 2 [Homo sapiens]                   76   9e-14
gi|4507241 structure specific recognition protein 1 [Homo sapiens]     75   1e-13
gi|56806673 high-mobility group box 1-like 1 [Homo sapiens]            74   3e-13
gi|83715964 high-mobility group 20B [Homo sapiens]                     71   2e-12
gi|71143137 high-mobility group box 3 [Homo sapiens]                   71   3e-12
gi|169168462 PREDICTED: similar to high mobility group box 3 [Ho...    70   5e-12
gi|169168166 PREDICTED: similar to high mobility group box 3 [Ho...    70   5e-12
gi|239742753 PREDICTED: similar to high mobility group box 3 iso...    70   5e-12
gi|113416897 PREDICTED: similar to high mobility group box 3 iso...    70   5e-12
gi|57232750 HMG2 like isoform 1 [Homo sapiens]                         65   2e-10
gi|57232748 HMG2 like isoform 2 [Homo sapiens]                         65   2e-10
gi|169184027 PREDICTED: similar to high mobility group box 3 [Ho...    64   4e-10
gi|113421073 PREDICTED: similar to high mobility group box 3 [Ho...    64   4e-10
gi|113420668 PREDICTED: similar to high mobility group box 3 [Ho...    64   4e-10
gi|8922633 high-mobility group 20A [Homo sapiens]                      63   6e-10

>gi|7662322 thymus high mobility group box protein TOX [Homo
           sapiens]
          Length = 526

 Score = 1095 bits (2831), Expect = 0.0
 Identities = 526/526 (100%), Positives = 526/526 (100%)

Query: 1   MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG 60
           MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG
Sbjct: 1   MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG 60

Query: 61  PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQNMDLPEITV 120
           PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQNMDLPEITV
Sbjct: 61  PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQNMDLPEITV 120

Query: 121 SNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLT 180
           SNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLT
Sbjct: 121 SNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLT 180

Query: 181 TINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPA 240
           TINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPA
Sbjct: 181 TINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPA 240

Query: 241 SDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWD 300
           SDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWD
Sbjct: 241 SDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWD 300

Query: 301 GLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFH 360
           GLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFH
Sbjct: 301 GLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFH 360

Query: 361 GPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP 420
           GPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP
Sbjct: 361 GPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP 420

Query: 421 LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTS 480
           LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTS
Sbjct: 421 LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTS 480

Query: 481 TAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT 526
           TAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT
Sbjct: 481 TAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT 526


>gi|149408144 TOX high mobility group box family member 2 isoform a
           [Homo sapiens]
          Length = 506

 Score =  397 bits (1020), Expect = e-110
 Identities = 246/544 (45%), Positives = 323/544 (59%), Gaps = 56/544 (10%)

Query: 1   MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG 60
           MDVR YP      A P A   G +  LD Y+  KFDG++ Y+ M++ + + +  SQ+Y G
Sbjct: 1   MDVRLYPSAPAVGARPGAEPAGLAH-LDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNG 59

Query: 61  PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHP-QNMDLPEIT 119
            S  +ED+ IPPITPP+LP+ SL+HL + E+ YHSLCH +  NGLLP +  Q MDLP I 
Sbjct: 60  QSENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIM 119

Query: 120 VSNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQL 179
           VSNML QD  LLS  +  + ++ + E   Y S          G+P  +  +P M+    +
Sbjct: 120 VSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDS----------GRPGPLLGRPAMLA-SHM 168

Query: 180 TTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRP 239
           + ++QSQL +Q+G+    S++ H+SPSPPGSKSATPSPSSS  E+E +   KI+G EKRP
Sbjct: 169 SALSQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISG-EKRP 224

Query: 240 ASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMW 299
           ++D GKK K PKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNP+ATFG+VSKIVASMW
Sbjct: 225 SADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMW 284

Query: 300 DGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQ---PPQLINSKP 356
           D LGEEQKQ YK+KTEAAKKEYLK LAAYRASLVSKS  +  + K++Q   P +++  K 
Sbjct: 285 DSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQ 344

Query: 357 SVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVS 416
            ++  P  A S L  S     + G +P       SL R +  K          +  ++ S
Sbjct: 345 PMYAMPGLA-SFLTPSDLQAFRSGASP------ASLARTLGSKS--------LLPGLSAS 389

Query: 417 PPPP--LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQT 474
           PPPP    +SP LHQ L++  H    +  P     P+ +  A   P +     LQ   Q 
Sbjct: 390 PPPPPSFPLSPTLHQQLSLPPHAQGALLSP-----PVSMSPAPQPPVLPTPMALQ--VQL 442

Query: 475 IINPTSTAAQVVTQAMEYVRS--GCRNPPPQPV---DWNNDYCSS-------GGMQRDKA 522
            ++P+    Q      E+  S   C   P  P    DW++ Y S          + RDK+
Sbjct: 443 AMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLPRDKS 502

Query: 523 LYLT 526
           LYLT
Sbjct: 503 LYLT 506


>gi|226054295 TOX high mobility group box family member 3 isoform 1
           [Homo sapiens]
          Length = 576

 Score =  380 bits (976), Expect = e-105
 Identities = 242/494 (48%), Positives = 305/494 (61%), Gaps = 48/494 (9%)

Query: 1   MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPAS-QSYP 59
           MDVRFYP     AAA D   L  + CL  Y  +KF   N YM+M E +  +  AS Q++ 
Sbjct: 1   MDVRFYP-----AAAGDPASLDFAQCLGYYGYSKFGNNNNYMNMAEANNAFFAASEQTFH 55

Query: 60  GPSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNG---LLPFHPQNMDLP 116
            PSL  E+F IPPITPP   D +L  + +V   + +L  P+   G      F PQ++DLP
Sbjct: 56  TPSLGDEEFEIPPITPPPESDPAL-GMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLP 114

Query: 117 EITVS-NMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMP 175
            IT+S N++ QDG L S+ + +  D  + + +QY   P +  MR      D  +  G+MP
Sbjct: 115 SITISRNLVEQDGVLHSSGLHM--DQSHTQVSQYRQDPSLI-MRSIVHMTDAARS-GVMP 170

Query: 176 HGQLTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGG 235
             QLTTINQSQLSAQLGLN+GG+++PH SPSPP SKSATPSPSSS++E++ D+ ++  G 
Sbjct: 171 PAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIG- 229

Query: 236 EKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIV 295
           EKR A D GKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIV
Sbjct: 230 EKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIV 289

Query: 296 ASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSK 355
           ASMWD LGEEQKQVYK+KTEAAKKEYLK LAAYRASLVSK+ +E  + +T +  Q   + 
Sbjct: 290 ASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLAS 349

Query: 356 PSVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPK------PNNQMPVTVS 409
            ++        S+L L++   Q   ++     +  SLPR+IAPK      P NQ+  +V+
Sbjct: 350 TNL-------TSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVT 402

Query: 410 I-ANM---------------AVSPPPPLQISPPL--HQH-LNMQQHQPLTMQQPLGNQLP 450
           I ANM                V   P  Q+SP +   QH + +QQ Q    QQ    Q  
Sbjct: 403 IAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQ 462

Query: 451 MQVQSALHSPTMQQ 464
              Q  +H    QQ
Sbjct: 463 QLQQHQMHQQIQQQ 476


>gi|149408141 TOX high mobility group box family member 2 isoform c
           [Homo sapiens]
          Length = 464

 Score =  369 bits (948), Expect = e-102
 Identities = 228/501 (45%), Positives = 300/501 (59%), Gaps = 55/501 (10%)

Query: 44  MTEPSQDYVPASQSYPGPSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHN 103
           M++ + + +  SQ+Y G S  +ED+ IPPITPP+LP+ SL+HL + E+ YHSLCH +  N
Sbjct: 1   MSDGNPELLSTSQTYNGQSENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPN 60

Query: 104 GLLPFHP-QNMDLPEITVSNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRG 162
           GLLP +  Q MDLP I VSNML QD  LLS  +  + ++ + E   Y S          G
Sbjct: 61  GLLPAYSYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDS----------G 110

Query: 163 QPADIRQQPGMMPHGQLTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVH 222
           +P  +  +P M+    ++ ++QSQL +Q+G+    S++ H+SPSPPGSKSATPSPSSS  
Sbjct: 111 RPGPLLGRPAMLA-SHMSALSQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQ 166

Query: 223 EDEGDDTSKINGGEKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQ 282
           E+E +   KI+G EKRP++D GKK K PKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQ
Sbjct: 167 EEESEVHFKISG-EKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQ 225

Query: 283 NPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVD 342
           NP+ATFG+VSKIVASMWD LGEEQKQ YK+KTEAAKKEYLK LAAYRASLVSKS  +  +
Sbjct: 226 NPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGE 285

Query: 343 VKTSQ---PPQLINSKPSVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPK 399
            K++Q   P +++  K  ++  P  A S L  S     + G +P       SL R +  K
Sbjct: 286 TKSTQANPPAKMLPPKQPMYAMPGLA-SFLTPSDLQAFRSGASP------ASLARTLGSK 338

Query: 400 PNNQMPVTVSIANMAVSPPPP--LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSAL 457
                     +  ++ SPPPP    +SP LHQ L++  H    +  P     P+ +  A 
Sbjct: 339 S--------LLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSP-----PVSMSPAP 385

Query: 458 HSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAMEYVRS--GCRNPPPQPV---DWNNDYC 512
             P +     LQ   Q  ++P+    Q      E+  S   C   P  P    DW++ Y 
Sbjct: 386 QPPVLPTPMALQ--VQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYP 443

Query: 513 SS-------GGMQRDKALYLT 526
           S          + RDK+LYLT
Sbjct: 444 SGECGISTCSLLPRDKSLYLT 464


>gi|14249636 TOX high mobility group box family member 2 isoform c
           [Homo sapiens]
          Length = 464

 Score =  369 bits (948), Expect = e-102
 Identities = 228/501 (45%), Positives = 300/501 (59%), Gaps = 55/501 (10%)

Query: 44  MTEPSQDYVPASQSYPGPSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHN 103
           M++ + + +  SQ+Y G S  +ED+ IPPITPP+LP+ SL+HL + E+ YHSLCH +  N
Sbjct: 1   MSDGNPELLSTSQTYNGQSENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPN 60

Query: 104 GLLPFHP-QNMDLPEITVSNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRG 162
           GLLP +  Q MDLP I VSNML QD  LLS  +  + ++ + E   Y S          G
Sbjct: 61  GLLPAYSYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDS----------G 110

Query: 163 QPADIRQQPGMMPHGQLTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVH 222
           +P  +  +P M+    ++ ++QSQL +Q+G+    S++ H+SPSPPGSKSATPSPSSS  
Sbjct: 111 RPGPLLGRPAMLA-SHMSALSQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQ 166

Query: 223 EDEGDDTSKINGGEKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQ 282
           E+E +   KI+G EKRP++D GKK K PKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQ
Sbjct: 167 EEESEVHFKISG-EKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQ 225

Query: 283 NPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVD 342
           NP+ATFG+VSKIVASMWD LGEEQKQ YK+KTEAAKKEYLK LAAYRASLVSKS  +  +
Sbjct: 226 NPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGE 285

Query: 343 VKTSQ---PPQLINSKPSVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPK 399
            K++Q   P +++  K  ++  P  A S L  S     + G +P       SL R +  K
Sbjct: 286 TKSTQANPPAKMLPPKQPMYAMPGLA-SFLTPSDLQAFRSGASP------ASLARTLGSK 338

Query: 400 PNNQMPVTVSIANMAVSPPPP--LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSAL 457
                     +  ++ SPPPP    +SP LHQ L++  H    +  P     P+ +  A 
Sbjct: 339 S--------LLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSP-----PVSMSPAP 385

Query: 458 HSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAMEYVRS--GCRNPPPQPV---DWNNDYC 512
             P +     LQ   Q  ++P+    Q      E+  S   C   P  P    DW++ Y 
Sbjct: 386 QPPVLPTPMALQ--VQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYP 443

Query: 513 SS-------GGMQRDKALYLT 526
           S          + RDK+LYLT
Sbjct: 444 SGECGISTCSLLPRDKSLYLT 464


>gi|226246533 TOX high mobility group box family member 3 isoform 2
           [Homo sapiens]
          Length = 571

 Score =  365 bits (937), Expect = e-101
 Identities = 226/460 (49%), Positives = 288/460 (62%), Gaps = 42/460 (9%)

Query: 34  KFDGENMYMSMTEPSQDYVPASQSYPGPSLESEDFNIPPITPPSLPDHSLVHLNEVESGY 93
           KF   N YM+M E +  +  AS+++  PSL  E+F IPPITPP   D +L  + +V   +
Sbjct: 25  KFGNNNNYMNMAEANNAFFAASETFHTPSLGDEEFEIPPITPPPESDPAL-GMPDVLLPF 83

Query: 94  HSLCHPMNHNG---LLPFHPQNMDLPEITVS-NMLGQDGTLLSNSISVMPDIRNPEGTQY 149
            +L  P+   G      F PQ++DLP IT+S N++ QDG L S+ + +  D  + + +QY
Sbjct: 84  QALSDPLPSQGSEFTPQFPPQSLDLPSITISRNLVEQDGVLHSSGLHM--DQSHTQVSQY 141

Query: 150 SSHPQMAAMRPRGQPADIRQQPGMMPHGQLTTINQSQLSAQLGLNMGGSNVPHNSPSPPG 209
              P +  MR      D  +  G+MP  QLTTINQSQLSAQLGLN+GG+++PH SPSPP 
Sbjct: 142 RQDPSLI-MRSIVHMTDAARS-GVMPPAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPA 199

Query: 210 SKSATPSPSSSVHEDEGDDTSKINGGEKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYA 269
           SKSATPSPSSS++E++ D+ ++  G EKR A D GKKPKTPKKKKKKDPNEPQKPVSAYA
Sbjct: 200 SKSATPSPSSSINEEDADEANRAIG-EKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYA 258

Query: 270 LFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYR 329
           LFFRDTQAAIKGQNPNATFGEVSKIVASMWD LGEEQKQVYK+KTEAAKKEYLK LAAYR
Sbjct: 259 LFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYR 318

Query: 330 ASLVSKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMH 389
           ASLVSK+ +E  + +T +  Q   +  ++        S+L L++   Q   ++     + 
Sbjct: 319 ASLVSKAAAESAEAQTIRSVQQTLASTNL-------TSSLLLNTPLSQHGTVSASPQTLQ 371

Query: 390 PSLPRNIAPK------PNNQMPVTVSI-ANM---------------AVSPPPPLQISPPL 427
            SLPR+IAPK      P NQ+  +V+I ANM                V   P  Q+SP +
Sbjct: 372 QSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSV 431

Query: 428 --HQH-LNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQ 464
              QH + +QQ Q    QQ    Q     Q  +H    QQ
Sbjct: 432 QTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQ 471


>gi|149408146 TOX high mobility group box family member 2 isoform b
           [Homo sapiens]
          Length = 488

 Score =  328 bits (840), Expect = 1e-89
 Identities = 209/516 (40%), Positives = 283/516 (54%), Gaps = 76/516 (14%)

Query: 26  CLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPGPSLESEDFNIPPITPPSLPDHSLVH 85
           C+   +  KFDG++ Y+ M++ + + +  SQ+Y G S  +ED+ IPPITPP+LP+ SL+H
Sbjct: 34  CIAGVFPQKFDGDSAYVGMSDGNPELLSTSQTYNGQSENNEDYEIPPITPPNLPEPSLLH 93

Query: 86  LNEVESGYHSLCHPMNHNGLLPFHP-QNMDLPEITVSNMLGQDGTLLSNSISVMPDIRNP 144
           L + E+ YHSLCH +  NGLLP +  Q MDLP I VSNML QD  LLS  +  + ++ + 
Sbjct: 94  LGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHS 153

Query: 145 EGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLTTINQSQLSAQLGLNMGGSNVPHNS 204
           E   Y S          G+P  +  +P M+    ++ ++QSQL +Q+G+    S++ H+S
Sbjct: 154 EVAAYDS----------GRPGPLLGRPAMLA-SHMSALSQSQLISQMGIR---SSIAHSS 199

Query: 205 PSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPASDMGKKPKTPKKKKKKDPNEPQKP 264
           PSPPGSKSATPSPSSS  E+E +   KI+G EKRP++D GKK K PKKKKKKDPNEPQKP
Sbjct: 200 PSPPGSKSATPSPSSSTQEEESEVHFKISG-EKRPSADPGKKAKNPKKKKKKDPNEPQKP 258

Query: 265 VSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQ 324
           VSAYALFFRDTQAAIKGQNP+ATFG+VSKIVASMWD LGEEQKQ                
Sbjct: 259 VSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQS--------------- 303

Query: 325 LAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSALYLSSHYHQQPGMNPH 384
                    S    E    + + P +++  K  ++  P  A S L  S     + G +P 
Sbjct: 304 ---------SPDQGETKSTQANPPAKMLPPKQPMYAMPGLA-SFLTPSDLQAFRSGASP- 352

Query: 385 LTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP--LQISPPLHQHLNMQQHQPLTMQ 442
                 SL R +  K          +  ++ SPPPP    +SP LHQ L++  H    + 
Sbjct: 353 -----ASLARTLGSKS--------LLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALL 399

Query: 443 QPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAMEYVRS--GCRNP 500
            P     P+ +  A   P +     LQ   Q  ++P+    Q      E+  S   C   
Sbjct: 400 SP-----PVSMSPAPQPPVLPTPMALQ--VQLAMSPSPPGPQDFPHISEFPSSSGSCSPG 452

Query: 501 PPQPV---DWNNDYCSS-------GGMQRDKALYLT 526
           P  P    DW++ Y S          + RDK+LYLT
Sbjct: 453 PSNPTSSGDWDSSYPSGECGISTCSLLPRDKSLYLT 488


>gi|7662274 epidermal Langerhans cell protein LCP1 [Homo sapiens]
          Length = 621

 Score =  287 bits (735), Expect = 1e-77
 Identities = 208/600 (34%), Positives = 295/600 (49%), Gaps = 133/600 (22%)

Query: 37  GENMYMSMTEPSQDYVPASQSYPGPSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSL 96
           G + Y+++T PS  ++  ++++  PSL  E+F IPPI+  S P    + +++V   +  L
Sbjct: 6   GNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPS---LAVSDVVGHFDDL 62

Query: 97  CHPMNHNG---LLPFHPQNMDLPEITVSNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHP 153
             P +         +  Q +D+P      ++ Q G LLS  +++  D+ +  GTQYS++P
Sbjct: 63  ADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTM--DLDHSIGTQYSANP 120

Query: 154 QMAAMRPRGQPADIRQQPGMMPHGQLTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSA 213
            +    P           G+M H QLTTI+QS+LS+QLGL++GG  +   + SP    S 
Sbjct: 121 PVTIDVPMTDMTS-----GLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLST 175

Query: 214 TPSPSSSVHEDEGDDTSKINGGEKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFR 273
           TPSP+SS+HED  +D  +    +K    + GKK K PKK+KKKDPNEPQKPVSAYALFFR
Sbjct: 176 TPSPTSSLHEDGVEDFRRQLPSQKTVVVEAGKKQKAPKKRKKKDPNEPQKPVSAYALFFR 235

Query: 274 DTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLV 333
           DTQAAIKGQNPNATFGEVSKIVASMWD LGEEQKQVYK+KTEAAKKEYLK LAAY+ +  
Sbjct: 236 DTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQE 295

Query: 334 SKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSA------------------LYLSSHY 375
            ++  E V++  + P Q  +  P     P+    A                   Y+++  
Sbjct: 296 CQATVETVELDPAPPSQTPSPPPMATVDPASPAPASIEPPALSPSIVVNSTLSSYVANQA 355

Query: 376 HQQPGMNPHLTAM---HPSLPRNIAPKPNNQ---MPVTV--------------------- 408
               G  P++T +      LP +I          +P TV                     
Sbjct: 356 SSGAGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQ 415

Query: 409 ----------------SIANMAVSP----PPPLQ--ISPPLHQHLN-MQQHQPL-TMQQP 444
                           + A+M + P    PPPLQ    PP  Q +  +QQ  PL  MQQP
Sbjct: 416 AQIVTRSVLQAAAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQP 475

Query: 445 LGNQL---------PMQVQSALHSPTMQQGFTL---------------QPDYQTIINPT- 479
              ++         P+Q++S +  PT++   TL                P+  T+  P+ 
Sbjct: 476 PPQKVRINLQQQPPPLQIKS-VPLPTLKMQTTLVPPTVESSPERPMNNSPEAHTVEAPSP 534

Query: 480 STAAQVVTQAM-------------------------EYVRSGCRNPPPQPVDWNNDYCSS 514
            T  +++T  +                           VRSGC NPP    DW+N+YCS+
Sbjct: 535 ETICEMITDVVPEVESPSQMDVELVSGSPVALSPQPRCVRSGCENPPIVSKDWDNEYCSN 594


>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 488

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 37/84 (44%), Positives = 55/84 (65%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK   KKK KDPN P++P SA+ L+F +    IKG+ P  +FG+V+K +  MW+    + 
Sbjct: 217 PKGETKKKFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADD 276

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRA 330
           KQ Y+K++   K++Y K +AAYRA
Sbjct: 277 KQPYEKRSAKLKEKYEKDIAAYRA 300


>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 487

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 37/84 (44%), Positives = 55/84 (65%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK   KKK KDPN P++P SA+ L+F +    IKG+ P  +FG+V+K +  MW+    + 
Sbjct: 217 PKGETKKKFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADD 276

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRA 330
           KQ Y+K++   K++Y K +AAYRA
Sbjct: 277 KQPYEKRSAKLKEKYEKDIAAYRA 300


>gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]
          Length = 486

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 37/84 (44%), Positives = 55/84 (65%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK   KKK KDPN P++P SA+ L+F +    IKG+ P  +FG+V+K +  MW+    + 
Sbjct: 217 PKGETKKKFKDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADD 276

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRA 330
           KQ Y+K++   K++Y K +AAYRA
Sbjct: 277 KQPYEKRSAKLKEKYEKDIAAYRA 300


>gi|4504425 high-mobility group box 1 [Homo sapiens]
          Length = 215

 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 37/84 (44%), Positives = 54/84 (64%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK   KKK KDPN P++P SA+ LF  + +  IKG++P  + G+V+K +  MW+    + 
Sbjct: 81  PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADD 140

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRA 330
           KQ Y+KK    K++Y K +AAYRA
Sbjct: 141 KQPYEKKAAKLKEKYEKDIAAYRA 164



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 2/76 (2%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPNAT--FGEVSKIVASMWDGLGEEQKQVYKK 312
           K DP +P+  +S+YA F +  +   K ++P+A+  F E SK  +  W  +  ++K  ++ 
Sbjct: 3   KGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFED 62

Query: 313 KTEAAKKEYLKQLAAY 328
             +A K  Y +++  Y
Sbjct: 63  MAKADKARYEREMKTY 78


>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
          Length = 879

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 52/84 (61%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK  KKKK KDPN P++P  A+ LF  + +  IKG++P  +  +V K +A MW+      
Sbjct: 755 PKGEKKKKFKDPNAPKRPPLAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAAD 814

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRA 330
           KQ Y+KK    K++Y K +AAYRA
Sbjct: 815 KQFYEKKAAKLKEKYKKDIAAYRA 838


>gi|194688135 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 4/108 (3%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK  KK KKKDPN P++P SA+ LF  + +  IK ++P  + G+ +K +  MW     + 
Sbjct: 81  PKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKD 140

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRASLVS----KSYSEPVDVKTSQPPQ 350
           KQ Y++K    K++Y K +AAYRA   S    K    P   K    P+
Sbjct: 141 KQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPE 188



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 24/140 (17%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPNAT--FGEVSKIVASMWDGLGEEQKQVYKK 312
           K DPN+P+  +S+YA F +  +   K ++P+++  F E SK  +  W  +  ++K  ++ 
Sbjct: 3   KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFED 62

Query: 313 KTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSALYLS 372
             ++ K  Y +++         K+Y  P   K          K    + P +  SA +L 
Sbjct: 63  MAKSDKARYDREM---------KNYVPPKGDK--------KGKKKDPNAPKRPPSAFFLF 105

Query: 373 SHYHQQPGMNPHLTAMHPSL 392
              H+     P + + HP L
Sbjct: 106 CSEHR-----PKIKSEHPGL 120


>gi|194688133 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 4/108 (3%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK  KK KKKDPN P++P SA+ LF  + +  IK ++P  + G+ +K +  MW     + 
Sbjct: 81  PKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKD 140

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRASLVS----KSYSEPVDVKTSQPPQ 350
           KQ Y++K    K++Y K +AAYRA   S    K    P   K    P+
Sbjct: 141 KQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPE 188



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 24/140 (17%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPNAT--FGEVSKIVASMWDGLGEEQKQVYKK 312
           K DPN+P+  +S+YA F +  +   K ++P+++  F E SK  +  W  +  ++K  ++ 
Sbjct: 3   KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFED 62

Query: 313 KTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSALYLS 372
             ++ K  Y +++         K+Y  P   K          K    + P +  SA +L 
Sbjct: 63  MAKSDKARYDREM---------KNYVPPKGDK--------KGKKKDPNAPKRPPSAFFLF 105

Query: 373 SHYHQQPGMNPHLTAMHPSL 392
              H+     P + + HP L
Sbjct: 106 CSEHR-----PKIKSEHPGL 120


>gi|11321591 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 4/108 (3%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK  KK KKKDPN P++P SA+ LF  + +  IK ++P  + G+ +K +  MW     + 
Sbjct: 81  PKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKD 140

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRASLVS----KSYSEPVDVKTSQPPQ 350
           KQ Y++K    K++Y K +AAYRA   S    K    P   K    P+
Sbjct: 141 KQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPE 188



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 24/140 (17%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPNAT--FGEVSKIVASMWDGLGEEQKQVYKK 312
           K DPN+P+  +S+YA F +  +   K ++P+++  F E SK  +  W  +  ++K  ++ 
Sbjct: 3   KGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFED 62

Query: 313 KTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSALYLS 372
             ++ K  Y +++         K+Y  P   K          K    + P +  SA +L 
Sbjct: 63  MAKSDKARYDREM---------KNYVPPKGDK--------KGKKKDPNAPKRPPSAFFLF 105

Query: 373 SHYHQQPGMNPHLTAMHPSL 392
              H+     P + + HP L
Sbjct: 106 CSEHR-----PKIKSEHPGL 120


>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
          Length = 709

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 43/164 (26%), Positives = 81/164 (49%), Gaps = 1/164 (0%)

Query: 212 SATPSPSSSVHEDEGDDTSKINGGEKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALF 271
           +A+ S SS+  + + D+  +    + + A D   + K  + KK KDPN P++P+SAY L+
Sbjct: 498 NASASSSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNAPKRPMSAYMLW 557

Query: 272 FRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRAS 331
              ++  IK  +P  +  ++SK    +W G+ +E+K+ + +K E A+++Y K +  Y   
Sbjct: 558 LNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARRDYEKAMKEYEGG 617

Query: 332 LVSKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSALYLSSHY 375
              +S       K  +    +  K +   G S   S+  LS  +
Sbjct: 618 R-GESSKRDKSKKKKKVKVKMEKKSTPSRGSSSKSSSRQLSESF 660


>gi|56806673 high-mobility group box 1-like 1 [Homo sapiens]
          Length = 211

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 35/84 (41%), Positives = 52/84 (61%)

Query: 247 PKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQ 306
           PK   KKK KDPN P++P SA+ LF  +    IKG++P  + G+V+K +  MW+    + 
Sbjct: 81  PKGETKKKFKDPNAPKRPPSAFFLFCSEYHPKIKGEHPGLSIGDVAKKLGEMWNNTAADD 140

Query: 307 KQVYKKKTEAAKKEYLKQLAAYRA 330
           KQ  +KK    K++Y K +AAY+A
Sbjct: 141 KQPGEKKAAKLKEKYEKDIAAYQA 164



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 33/143 (23%), Positives = 58/143 (40%), Gaps = 30/143 (20%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPNAT--FGEVSKIVASMWDGLGEEQKQVYKK 312
           K DP +P+  +S+YA F +  +   K ++ +A+  F E S   +  W  +  ++K  ++ 
Sbjct: 3   KGDPKKPRGKMSSYAFFVQTCREEHKKKHSDASVNFSEFSNKCSERWKTMSAKEKGKFED 62

Query: 313 KTEAAKKEYLKQLAAY--RASLVSKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSALY 370
             +A K  Y +Q+  Y        K + +P                   + P +  SA +
Sbjct: 63  MAKADKTHYERQMKTYIPPKGETKKKFKDP-------------------NAPKRPPSAFF 103

Query: 371 L-SSHYHQQPGMNPHLTAMHPSL 392
           L  S YH      P +   HP L
Sbjct: 104 LFCSEYH------PKIKGEHPGL 120


>gi|83715964 high-mobility group 20B [Homo sapiens]
          Length = 317

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 43/151 (28%), Positives = 72/151 (47%), Gaps = 9/151 (5%)

Query: 203 NSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPASDMGKKPKTP---------KKK 253
           + P  PG+ +A     +         T K   GE   A + G   + P         KK+
Sbjct: 3   HGPKQPGAAAAPAGGKAPGQHGGFVVTVKQERGEGPRAGEKGSHEEEPVKKRGWPKGKKR 62

Query: 254 KKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKK 313
           KK  PN P+ PV+ Y  F  + +  I+ ++P+  F E++K++ + W  L   +KQ Y  +
Sbjct: 63  KKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPTEKQRYLDE 122

Query: 314 TEAAKKEYLKQLAAYRASLVSKSYSEPVDVK 344
            E  K++Y+K+L AY+ S   K  +E +  K
Sbjct: 123 AEREKQQYMKELRAYQQSEAYKMCTEKIQEK 153


>gi|71143137 high-mobility group box 3 [Homo sapiens]
          Length = 200

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 39/111 (35%), Positives = 59/111 (53%), Gaps = 12/111 (10%)

Query: 232 INGGEKRPASDMGKKPKT----------PKK--KKKKDPNEPQKPVSAYALFFRDTQAAI 279
           ++G EK    +M K  K           P K  KKKKDPN P++P S + LF  + +  I
Sbjct: 52  MSGKEKSKFDEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKI 111

Query: 280 KGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRA 330
           K  NP  + G+V+K +  MW+ L + +KQ Y  K    K++Y K +A Y++
Sbjct: 112 KSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKS 162



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPN--ATFGEVSKIVASMWDGLGEEQKQVYKK 312
           K DP +P+  +SAYA F +  +   K +NP     F E SK  +  W  +  ++K  + +
Sbjct: 3   KGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDE 62

Query: 313 KTEAAKKEYLKQLAAYRASLVSKSYSEP 340
             +A K  Y +++  Y  +   K   +P
Sbjct: 63  MAKADKVRYDREMKDYGPAKGGKKKKDP 90


>gi|169168462 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 204

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 37/103 (35%), Positives = 57/103 (55%), Gaps = 2/103 (1%)

Query: 226 GDDTSKINGGEKRPASDMGKKPKTPKK--KKKKDPNEPQKPVSAYALFFRDTQAAIKGQN 283
           G + SK +   K       ++ K P K  KKKKDP+ P++P S + LF  + +  IK  N
Sbjct: 51  GKEKSKFDEMAKTDKVHCDREMKGPAKGGKKKKDPSAPKRPPSGFFLFSSEIRPKIKSTN 110

Query: 284 PNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLA 326
           P  + G+V+K +  MW+ L + +KQ Y  KT   K++Y K +A
Sbjct: 111 PGISIGDVAKKLGEMWNNLNDSEKQPYITKTAKLKEKYEKDVA 153



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKT 314
           K DP +P+  +SAY  F +  +   K +NP   F E SK  +  W  +  ++K  + +  
Sbjct: 3   KGDPKKPKGKMSAYVFFVQTCREECKKKNP-VNFAEFSKKCSERWKTMSGKEKSKFDEMA 61

Query: 315 EAAK 318
           +  K
Sbjct: 62  KTDK 65


>gi|169168166 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 204

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 37/103 (35%), Positives = 57/103 (55%), Gaps = 2/103 (1%)

Query: 226 GDDTSKINGGEKRPASDMGKKPKTPKK--KKKKDPNEPQKPVSAYALFFRDTQAAIKGQN 283
           G + SK +   K       ++ K P K  KKKKDP+ P++P S + LF  + +  IK  N
Sbjct: 51  GKEKSKFDEMAKTDKVHCDREMKGPAKGGKKKKDPSAPKRPPSGFFLFSSEIRPKIKSTN 110

Query: 284 PNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLA 326
           P  + G+V+K +  MW+ L + +KQ Y  KT   K++Y K +A
Sbjct: 111 PGISIGDVAKKLGEMWNNLNDSEKQPYITKTAKLKEKYEKDVA 153



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKT 314
           K DP +P+  +SAY  F +  +   K +NP   F E SK  +  W  +  ++K  + +  
Sbjct: 3   KGDPKKPKGKMSAYVFFVQTCREECKKKNP-VNFAEFSKKCSERWKTMSGKEKSKFDEMA 61

Query: 315 EAAK 318
           +  K
Sbjct: 62  KTDK 65


>gi|239742753 PREDICTED: similar to high mobility group box 3
           isoform 2 [Homo sapiens]
          Length = 183

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 37/103 (35%), Positives = 57/103 (55%), Gaps = 2/103 (1%)

Query: 226 GDDTSKINGGEKRPASDMGKKPKTPKK--KKKKDPNEPQKPVSAYALFFRDTQAAIKGQN 283
           G + SK +   K       ++ K P K  KKKKDP+ P++P S + LF  + +  IK  N
Sbjct: 33  GKEKSKFDEMAKTDKVHCDREMKGPAKGGKKKKDPSAPKRPPSGFFLFSSEIRPKIKSTN 92

Query: 284 PNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLA 326
           P  + G+V+K +  MW+ L + +KQ Y  KT   K++Y K +A
Sbjct: 93  PGISIGDVAKKLGEMWNNLNDSEKQPYITKTAKLKEKYEKDVA 135


>gi|113416897 PREDICTED: similar to high mobility group box 3
           isoform 1 [Homo sapiens]
          Length = 201

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 37/103 (35%), Positives = 57/103 (55%), Gaps = 2/103 (1%)

Query: 226 GDDTSKINGGEKRPASDMGKKPKTPKK--KKKKDPNEPQKPVSAYALFFRDTQAAIKGQN 283
           G + SK +   K       ++ K P K  KKKKDP+ P++P S + LF  + +  IK  N
Sbjct: 51  GKEKSKFDEMAKTDKVHCDREMKGPAKGGKKKKDPSAPKRPPSGFFLFSSEIRPKIKSTN 110

Query: 284 PNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLA 326
           P  + G+V+K +  MW+ L + +KQ Y  KT   K++Y K +A
Sbjct: 111 PGISIGDVAKKLGEMWNNLNDSEKQPYITKTAKLKEKYEKDVA 153



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKT 314
           K DP +P+  +SAY  F +  +   K +NP   F E SK  +  W  +  ++K  + +  
Sbjct: 3   KGDPKKPKGKMSAYVFFVQTCREECKKKNP-VNFAEFSKKCSERWKTMSGKEKSKFDEMA 61

Query: 315 EAAK 318
           +  K
Sbjct: 62  KTDK 65


>gi|57232750 HMG2 like isoform 1 [Homo sapiens]
          Length = 186

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 27/79 (34%), Positives = 49/79 (62%)

Query: 251 KKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVY 310
           KK++K+DP EP++P S++ LF +D  A +K +NPN +  +V+K    MW    + +K  Y
Sbjct: 83  KKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSVVQVAKATGKMWSTATDLEKHPY 142

Query: 311 KKKTEAAKKEYLKQLAAYR 329
           +++    + +Y ++L  YR
Sbjct: 143 EQRVALLRAKYFEELELYR 161



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 19/127 (14%)

Query: 260 EPQKPVSAYALFFRDTQAAIKGQNPNATFG--EVSKIVASMWDGLGEEQKQVYKKKTEAA 317
           +P+  VS+Y  F  + +   K Q PN   G  E S+  +  W  + + +K  Y+   +  
Sbjct: 8   KPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKYEALAKLD 67

Query: 318 KKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFHGPSQAHSALYLSSHYHQ 377
           K  Y +++  Y    V K        +  + PQ     PS F         L+   HY Q
Sbjct: 68  KARYQEEMMNY----VGKRKK-----RRKRDPQEPRRPPSSF--------LLFCQDHYAQ 110

Query: 378 QPGMNPH 384
               NP+
Sbjct: 111 LKRENPN 117


>gi|57232748 HMG2 like isoform 2 [Homo sapiens]
          Length = 112

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 27/79 (34%), Positives = 49/79 (62%)

Query: 251 KKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVY 310
           KK++K+DP EP++P S++ LF +D  A +K +NPN +  +V+K    MW    + +K  Y
Sbjct: 9   KKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSVVQVAKATGKMWSTATDLEKHPY 68

Query: 311 KKKTEAAKKEYLKQLAAYR 329
           +++    + +Y ++L  YR
Sbjct: 69  EQRVALLRAKYFEELELYR 87


>gi|169184027 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 29/75 (38%), Positives = 44/75 (58%)

Query: 251 KKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVY 310
           K  KKKDPN P++P S + LF  + +  IK  NP  + G+V+K +  MW+ L + +KQ Y
Sbjct: 82  KGGKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPY 141

Query: 311 KKKTEAAKKEYLKQL 325
             K    K++Y K +
Sbjct: 142 VTKAAKLKEKYEKDV 156



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPN--ATFGEVSKIVASMWDGLGEEQKQVYKK 312
           K DP +PQ  +SAYA   +      K +NP     F E SK  +  W  +  ++K  + +
Sbjct: 3   KGDPKKPQGKMSAYAFSVQTCCKEHKKKNPEVLVNFAEFSKKCSGRWKTMSSKEKFKFGE 62

Query: 313 KTEAAKKEYLKQLAAY 328
             +A +  Y +++  Y
Sbjct: 63  MAKADEVCYDREMKDY 78


>gi|113421073 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 29/75 (38%), Positives = 44/75 (58%)

Query: 251 KKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVY 310
           K  KKKDPN P++P S + LF  + +  IK  NP  + G+V+K +  MW+ L + +KQ Y
Sbjct: 82  KGGKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPY 141

Query: 311 KKKTEAAKKEYLKQL 325
             K    K++Y K +
Sbjct: 142 VTKAAKLKEKYEKDV 156



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPN--ATFGEVSKIVASMWDGLGEEQKQVYKK 312
           K DP +PQ  +SAYA   +      K +NP     F E SK  +  W  +  ++K  + +
Sbjct: 3   KGDPKKPQGKMSAYAFSVQTCCKEHKKKNPEVPVNFAEFSKKCSGRWKTMSSKEKFKFGE 62

Query: 313 KTEAAKKEYLKQLAAY 328
             +A +  Y +++  Y
Sbjct: 63  MAKADEVCYDREMKDY 78


>gi|113420668 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 29/75 (38%), Positives = 44/75 (58%)

Query: 251 KKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVY 310
           K  KKKDPN P++P S + LF  + +  IK  NP  + G+V+K +  MW+ L + +KQ Y
Sbjct: 82  KGGKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPY 141

Query: 311 KKKTEAAKKEYLKQL 325
             K    K++Y K +
Sbjct: 142 VTKAAKLKEKYEKDV 156



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 255 KKDPNEPQKPVSAYALFFRDTQAAIKGQNPN--ATFGEVSKIVASMWDGLGEEQKQVYKK 312
           K DP +PQ  +SAYA   +      K +NP     F E SK  +  W  +  ++K  + +
Sbjct: 3   KGDPKKPQGKMSAYAFSVQTCCKEHKKKNPEVPVNFAEFSKKCSGRWKTMSSKEKFKFGE 62

Query: 313 KTEAAKKEYLKQLAAY 328
             +A +  Y +++  Y
Sbjct: 63  MAKADEVCYDREMKDY 78


>gi|8922633 high-mobility group 20A [Homo sapiens]
          Length = 347

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 37/149 (24%), Positives = 71/149 (47%), Gaps = 13/149 (8%)

Query: 203 NSPSPPGSKSATPSPSSSVHEDE--------GDDTSKINGGEKRPASDMGKK----PKTP 250
           N P  P S  AT S ++    ++         + ++   G E+R   +   K     K  
Sbjct: 32  NHPEVPYSSGATSSTNNPEFVEDLSQGQLLQSESSNAAEGNEQRHEDEQRSKRGGWSKGR 91

Query: 251 KKKKK-KDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQV 309
           K+KK  +D N P+ P++ Y  F  + +  ++ + P   F E+++++ + W  L  E+KQ 
Sbjct: 92  KRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQR 151

Query: 310 YKKKTEAAKKEYLKQLAAYRASLVSKSYS 338
           Y  + +  K+ Y+K+L  Y+ +   K +S
Sbjct: 152 YLDEADRDKERYMKELEQYQKTEAYKVFS 180


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,435,173
Number of Sequences: 37866
Number of extensions: 1477959
Number of successful extensions: 9059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 390
Number of HSP's that attempted gapping in prelim test: 7737
Number of HSP's gapped (non-prelim): 1586
length of query: 526
length of database: 18,247,518
effective HSP length: 107
effective length of query: 419
effective length of database: 14,195,856
effective search space: 5948063664
effective search space used: 5948063664
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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